LOCUS       DBMDUW010000001       144460 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_152_length_144460_cov_5.099807, whole genome shotgun sequence.
ACCESSION   DBMDUW010000001 DBMDUW010000000
VERSION     DBMDUW010000001.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 144460)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 144460)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..144460
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_152_length_144460_cov_5.099807"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(195..283)
                     /locus_tag="ACZPCR_00005"
     tRNA            complement(195..283)
                     /locus_tag="ACZPCR_00005"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(247..249),aa:Ser,seq:gga)
     gene            complement(319..404)
                     /locus_tag="ACZPCR_00010"
     tRNA            complement(319..404)
                     /locus_tag="ACZPCR_00010"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(367..369),aa:Ser,seq:tga)
     gene            complement(737..1867)
                     /locus_tag="ACZPCR_00015"
     CDS             complement(737..1867)
                     /locus_tag="ACZPCR_00015"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HIR1229306.1"
                     /translation="MGEMQECYRSGEKIEYPEQMFSEGFSRQQEEECCRLIARLARGE
                     ILSRDEWILLLSVRTGKTAGLLFRTARRVREHFYGKRVFLRGAAELGSFSQNGGLQEE
                     YLMKQAVASACRDGKQAGLRSFVLQKSQEKSREKEQEGGLLADLIKQIKAACPDCAVT
                     LAAGIYPEETVHMWRQAGADRYLVRLERSEAAGRAGDSSRKALEQEKSGRKRYLNFLK
                     KTGWQTGGEISAASFAGFPERLAEELMFLCALQPEIVEINPFLFGDSVQTAEAREDAL
                     KMTLYLMGIARLLLPRVLLPVSEILEKSLPDGRRLGLLCGANVLMMDLLPGSGGSGPY
                     MGCSTAQEKAKLRRLVEAIGYEMVAERGDCYGFSRSGCSEKA"
     gene            complement(1915..2625)
                     /gene="ispD"
                     /locus_tag="ACZPCR_00020"
     CDS             complement(1915..2625)
                     /gene="ispD"
                     /locus_tag="ACZPCR_00020"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002601510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HIR1229307.1"
                     /translation="MKRQTCAIVLAAGQGKRMGTRIQKQFLDLGGYPVLFYSLNAFEK
                     SQVDQVILVTGKQEMEFCRQDLVERYGFSKVKAVVAGGAERYHSVCEGLKQVPASSAI
                     VLIHDGARPFVDSEIIDRTIEAAEQFGACAAGMPSKDTVKIADENGFAASTPDRSRVW
                     MVQTPQAFSRSLICQAYETMMEDESLQQGVTDDAMVVERLTGVPVRLVEGSYENIKVT
                     TPEDMEVAAAVLKRRGMI"
     gene            complement(2659..3696)
                     /gene="tsaD"
                     /locus_tag="ACZPCR_00025"
     CDS             complement(2659..3696)
                     /gene="tsaD"
                     /locus_tag="ACZPCR_00025"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HIR1229308.1"
                     /translation="MNRQETNEDVLILAIESSCDETAASVVKNGREVLSNVISSQIAL
                     HTLYGGVVPEIASRKHIEKINQVIESALAEADVTLEEITAIAVTYGPGLVGALLVGVA
                     EAKALAYAAKKPLVGVHHIEGHVSANFIENPDLEPPFVCLIVSGGHTHLVIVKDYGEF
                     EIIGHTRDDAAGEAFDKVARAVGLGYPGGPKVDKAAREGNPHAIEFPRAKVGDNPYDF
                     SFSGLKSAVLNYINHAKMTGEEICVPDLAASFQNAVVESLVSRAIMAAKEYGYDKLAI
                     AGGVASNSALREGMKAACEKEGIRFYHPSPIYCTDNAAMIGAAAYYEYQKGARSGWDL
                     NAVPNLKLGER"
     gene            complement(3717..4628)
                     /locus_tag="ACZPCR_00030"
     CDS             complement(3717..4628)
                     /locus_tag="ACZPCR_00030"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity
                     producing 5'-phosphomonoesters, hydrolytic mechanism
                     [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HIR1229309.1"
                     /translation="MLDVCLLGTGGMMPLPYRWLTSLMTRCDGSNLLIDCGEGTQVAL
                     KEKGWSPKPIDIICFTHYHADHISGLPGLLLTMGNAERTEPVTMIGPKGLERVVGALR
                     TIAPELPFELRFIELTEQREQLQIGPYIIDAYRVNHNVICYGYAVSIPRKGKFDVDRA
                     REQDIPQRFWNRLQKGETIEEEGRLLTPDMVLGPARRGIKVVYCTDTRPVPVIAEYAR
                     EADLFICEGMYGEDGKEAKAREYKHMTFQEAAGLAKEAQPKEMWLTHYSPSLTRPDEY
                     ADKARAIFARAKTARDGWSAELGFDED"
     gene            complement(4812..5144)
                     /locus_tag="ACZPCR_00035"
     CDS             complement(4812..5144)
                     /locus_tag="ACZPCR_00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009244322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS biosynthesis protein"
                     /protein_id="HIR1229310.1"
                     /translation="MVIEHNPKELAAMAEFHKGNRAQGLKLQEEFASEFREEYKDKDH
                     CPCKKACRYHGNCKECVAIHRAHQEHVPNCMRPVLNQKIKLLSELTEHTIAGEIEMPK
                     EVLRKEFQ"
     gene            complement(5241..5483)
                     /locus_tag="ACZPCR_00040"
     CDS             complement(5241..5483)
                     /locus_tag="ACZPCR_00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229311.1"
                     /translation="MRKYKGKGELESVWCNWCGKRLIVKDGILREGSAHFELTWDYFS
                     EKDGEVHSFDLCESCYDELTNQFKISVQVKERTELL"
     gene            complement(5647..6204)
                     /gene="rimI"
                     /locus_tag="ACZPCR_00045"
     CDS             complement(5647..6204)
                     /gene="rimI"
                     /locus_tag="ACZPCR_00045"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007707489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 - protein-N-terminal-alanine
                     acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HIR1229312.1"
                     /translation="MNRTGNGDRKEGSGNMNRSETGFSLRPMEERDLAAAAELERLSF
                     SAPWSEAILQESLESRLDFLWVLEPADNRTGGDCGQEKEGGHCGRGLAGYCNLRVIAG
                     EGELMRIAVHPELRGRGLSRKLMDQLEETAREKGAEALTLEVRKSNRTAIELYKSYGF
                     GEEAVRKNYYENPAEDALIMWLYFS"
     gene            complement(6224..6976)
                     /gene="tsaB"
                     /locus_tag="ACZPCR_00050"
     CDS             complement(6224..6976)
                     /gene="tsaB"
                     /locus_tag="ACZPCR_00050"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009533475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HIR1229313.1"
                     /translation="MRVLGIESSSLVASVAIVTDGILTAEYTVNLKKTHSQTLLPMID
                     EVIRMLEIELDTIDAIAVSGGPGSFTGLRIGSATAKGLGLAMKKPLIHVPTVDAMAYN
                     LYGTDALICPIMDARRNQVYTGLYHFREEFEIVKEQQPADIKELVEELNGRGERVIFL
                     GDGVPPYQAVIEELIKVPHRFAPAHVNRQRAASVAALGSVYLAEGKTETAMEHKPDYL
                     RKSQAERERELAERQGELDKLAAGIQVVEKQA"
     gene            complement(6973..7404)
                     /gene="tsaE"
                     /locus_tag="ACZPCR_00055"
     CDS             complement(6973..7404)
                     /gene="tsaE"
                     /locus_tag="ACZPCR_00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007869185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HIR1229314.1"
                     /translation="MKIIETYSPEETFQAGKRLGEQAGKGQVYCLDGDLGVGKTVFTQ
                     GFAKGLGIQSDVNSPTFTIIQQYEEGRLPLYHFDVYRIGDISEMDEIGYEDCFYGEGV
                     CLIEWASLVEEIIPETAIEIRIEKDLEKGFDYRKITVEERQ"
     gene            complement(7561..8637)
                     /gene="prfA"
                     /locus_tag="ACZPCR_00060"
     CDS             complement(7561..8637)
                     /gene="prfA"
                     /locus_tag="ACZPCR_00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HIR1229315.1"
                     /translation="MFDRLDDLLIRYEELMEELNNPYVVEDQKKFRKLMKEQADLAPI
                     VEAYKNYKQAHQDVEDSVALLEEESDEEMRELAKEELADAKKRIEELEQELKILLLPK
                     DPNDDKNVMVEIRAGAGGDEAALFASELYRMYVRYAERQRWKTEIVSLNENGIGGFKE
                     VVFMVTGQGAYSKLKYESGVHRVQRVPETESGGRIHTSTATVAVMPEAEDVDIEIDMN
                     DCRIDVMRASGNGGQCVNTTDSAVRLTHMPTGIVIYSQTEKSQLQNKEKAFRLLRSKL
                     YDLELERRQNEESEARRSQIGTGDRSEKIRTYNFPQGRVTEHRIKLTLYKIDSVMDGD
                     LDELIDSLIAADQAAKLAKLNEEI"
     gene            complement(8666..9733)
                     /locus_tag="ACZPCR_00065"
     CDS             complement(8666..9733)
                     /locus_tag="ACZPCR_00065"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003509632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N5-glutamine methyltransferase family protein"
                     /protein_id="HIR1229316.1"
                     /translation="MNRTVTACLFEGPFEELPTWQEMLDAGAGRLSAAGVAEAELDAW
                     YLLSDSFSVDRVHFLMDRNRTVHPGTFEKGWPVFAERIGRRALRIPLQQILGCQEFMG
                     LSFQVNDQVLIPRQDTETLVEEILKDCQNRDVEILDLCTGSGCIGLSLAVLGRYRSVS
                     AADISEGALKIALKNARNLFMIQKNVIRSQSKKVSDQPWRMELSVWTGEAEKGRNGAG
                     IFGNRPRTGRPLEVEERSFSLFQSDLFSADDGRLYDVIVSNPPYIPSAVVDSLEPEVR
                     EHEPRLALDGREDGLYFYRRLAEECGRHLKPGGRVYFEIGHDQGAAVTALLEENGYRN
                     IQVIKDAPGLDRVVKAEAAGR"
     gene            complement(9730..10731)
                     /locus_tag="ACZPCR_00070"
     CDS             complement(9730..10731)
                     /locus_tag="ACZPCR_00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016360331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HIR1229317.1"
                     /translation="MKYSGIGGQAVIEGIMMMNRNDYAVAVRKPDQEIEVKRDRYISI
                     TQKVKLFSLPFVRGVFRFADSMIVGMKTLTYSASFFEDDEDSEPGKIEQFLNRVLGEK
                     LESALMALVMVLSFVMAIGIFMLLPLFIAGLFSSVIESERLMAVLEGIIRILIFIAYI
                     KLVSRMEDIRRTFMYHGAEHKCINCVEHGLPLTVENVRNSSKEHKRCGTSFILIVMVI
                     SILFFMVVRVDNVWMRFASRIVLVPVIAGVSYEILQLAGRSNSRFMDLVSRPGMWMQG
                     LTTREPDDSMIEVAIAATEAVFDWKAYLRENFPDTDLSAFEDSEDSQEKEEALRRDA"
     gene            complement(10814..11020)
                     /gene="rpmE"
                     /locus_tag="ACZPCR_00075"
     CDS             complement(10814..11020)
                     /gene="rpmE"
                     /locus_tag="ACZPCR_00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002568352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HIR1229318.1"
                     /translation="MKEGIHPAYYQAKVVCNCGNEFVTGSTKKDIHVEVCSKCHSFYT
                     GQQKAAAARGRIDKFNRKYGISAN"
     gene            complement(11225..12991)
                     /gene="rho"
                     /locus_tag="ACZPCR_00080"
     CDS             complement(11225..12991)
                     /gene="rho"
                     /locus_tag="ACZPCR_00080"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: protein motif:HMM:TIGR00767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HIR1229319.1"
                     /translation="MREKLQTLPLVQLRELAKTQGIKGVTTLKKAELIERLCEKTDDK
                     TPDKAVDKAAVHMPERAGEGESYRERPAEPAREKTPEQEERPARTYQQRNYGRNENNS
                     NYRGSQNYRGNNYRNSSGRSYPQNNSGVHAGSQEGGCQQGADRSDVRNEGRAQESRYQ
                     DGRMQDARYQDSRVQENRYQQGRIQESGYQENRIHEYRENTVEDVKADLQELDSGIEA
                     KGILEVMSDGFGFIRCENFLPGDNDVYVAPSQIRRFNLKTGDIVQGSRRIKTATEKFA
                     ALLYIETINGYPTSVVERRPNFESLTPIFPDERLHMEMPGTRNSTAMRVLDLLSPIGK
                     GQRGMIVSPPKAGKTTLLKQVAKAVTVNHPDMHLMILLIDERPEEVTDIKEAITGPNV
                     EVIYSTFDELPDRHKRVSEMVIERAKRLVEHGRDVMILLDSITRLARAYNLVVPASGR
                     TLSGGLDPAALHMPKRFFGAARNIREGGSLTILATALIDTGSRMDDVIYEEFKGTGNM
                     EIVLDRKLSEKRIFPAIDILKSGTRRDDLLLNPLETEAVDIIHKATNTAKPEESVERI
                     LDLFARTKNNREFVDMVKKVRI"
     gene            13393..13857
                     /locus_tag="ACZPCR_00085"
     CDS             13393..13857
                     /locus_tag="ACZPCR_00085"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008723942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HIR1229320.1"
                     /translation="MDYLTMTIGKQKNIALIAHDQKKRELIDWCNAHKEVLKHHFLCG
                     TGTTARMITEATELPVKGYNSGPLGGDQQIGAKVVEGRVDFIVFFSDPLTAQPHDPDV
                     KALLRIAQVYDIPIANNKATADFLITSSYMNSEYEHRVINFQENIAKRAKSL"
     gene            complement(13947..14642)
                     /gene="rplA"
                     /locus_tag="ACZPCR_00090"
     CDS             complement(13947..14642)
                     /gene="rplA"
                     /locus_tag="ACZPCR_00090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007869556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HIR1229321.1"
                     /translation="MKRGKRYVEAAKLVDRTNLYEASEAISIVKKAAGAKFDETIEAH
                     IRTGCDGRHADQQIRGAVVLPHGTGKTVRILVFAKGPKADEAQAAGADFVGAEELIPK
                     IQNEGWLDFDVVVATPDMMGVVGRLGRVLGPKGLMPNPKAGTVTMDVTKAINDIKAGK
                     IEYRLDKTNIIHVPVGKASFTEEQLADNFQTLIDAVLKAKPATLKGAYFKSVTLTSTM
                     GPGVKLNVAKLTN"
     gene            complement(14729..15154)
                     /gene="rplK"
                     /locus_tag="ACZPCR_00095"
     CDS             complement(14729..15154)
                     /gene="rplK"
                     /locus_tag="ACZPCR_00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016293571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HIR1229322.1"
                     /translation="MAKKVTGYIKLQIPAGKATPAPPVGPALGQHGVNIVQFTKEFNA
                     RTADQGDLVIPVVITVYADRSFSFITKTPPAAVLLKKACKLKSGSATPNKTKVATISK
                     DEVRKIAELKMPDLNAANVEAAMSMIAGTARSMGITVEE"
     gene            complement(15229..15744)
                     /gene="nusG"
                     /locus_tag="ACZPCR_00100"
     CDS             complement(15229..15744)
                     /gene="nusG"
                     /locus_tag="ACZPCR_00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HIR1229323.1"
                     /translation="MSEANWYVVHTYSGYENKVKVDIEKTIENRGLQDQILEVSVPMQ
                     DVVEIKNGAQKQVAKKMFPGYVLINMVMNDDTWYVVRNTRGVTGFVGPGSKPVPLTED
                     EMANLGFKPAGVVVDYEVGDAVVVISGAWKDTVGVIKSINDNKQTLEITVEMFGRETP
                     VELDFTEVKKM"
     gene            complement(15770..15973)
                     /gene="secE"
                     /locus_tag="ACZPCR_00105"
     CDS             complement(15770..15973)
                     /gene="secE"
                     /locus_tag="ACZPCR_00105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003502674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HIR1229324.1"
                     /translation="MGETGNTAKAPKKSFWKGLKAEYKKIIWPDKATLQKQTAAVISG
                     AVALGLIIAALDTAIVFLLHYII"
     gene            complement(16030..16179)
                     /gene="rpmG"
                     /locus_tag="ACZPCR_00110"
     CDS             complement(16030..16179)
                     /gene="rpmG"
                     /locus_tag="ACZPCR_00110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013271142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HIR1229325.1"
                     /translation="MRTRITLACTECKQRNYNMTKDKKTHPDRMETKKYCRFCKRHTM
                     HKETK"
     gene            complement(16483..16854)
                     /locus_tag="ACZPCR_00115"
     CDS             complement(16483..16854)
                     /locus_tag="ACZPCR_00115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HIR1229326.1"
                     /translation="MGCLGNILWFIFGGCISGLSWCLAGCLWCVTIIGIPVGLQCFKL
                     ASLSFFPFGKEVRYGGGAVSFLVNLIWLVLSGLPLALEHALIGLLLCVTVIGIPFGLQ
                     QFKLAKLALMPFGAECVRTQI"
     gene            complement(16906..17820)
                     /locus_tag="ACZPCR_00120"
     CDS             complement(16906..17820)
                     /locus_tag="ACZPCR_00120"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229327.1"
                     /translation="MKRKVWVGMVGMLAASALCTGCQAEQADETRTAAETQMRTEETA
                     QGQEEDMHAVSIIGGADGPASVFVAGKMTDAEEISGCPSFSGQAQELLIDPDKTGRVY
                     LDSVHSYLQLTDENGEQLTNPEERTAAVIHGLWGTAVLARQEGESVWRTGTAADMKAV
                     EDSYMKDEQSTEVFANNGTVFVYQMENGNIEKEYHIVMETGQLFARDVSEEDAGEKLA
                     FYEMLREIRDEEENRKPAAEADREERLNRLKEEQEITNVWDRTVTADGAEVFLCSRGE
                     KLKDLCLAWEDPESGTWKVGTIVWNQES"
     gene            complement(18078..18569)
                     /locus_tag="ACZPCR_00125"
     CDS             complement(18078..18569)
                     /locus_tag="ACZPCR_00125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002601784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HIR1229328.1"
                     /translation="MKIRPAVQEDVREMMEIFNYEVRNSTASFAITEQSYEERLAWFW
                     SHGGERHPLIAAEQDGRVAGYACLSDYRPYEAYKGTAELSVYVSRDFRRQGIGEALMR
                     ELLDMARSCGKLHTVISVITGNNEASIRLHEKMGFSYCGTMHRAGEKFGQLLDIVNYE
                     FLI"
     gene            complement(18575..19336)
                     /locus_tag="ACZPCR_00130"
     CDS             complement(18575..19336)
                     /locus_tag="ACZPCR_00130"
                     /inference="COORDINATES: protein motif:HMM:NF025675.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcxB family protein"
                     /protein_id="HIR1229329.1"
                     /translation="MKEYTYQLEKDDYREWIQWNIKKHDQKKVRYITVGVMMALLAMT
                     LIGNLSSGAPLAAAVGSSIMFLGLGAIMLYFTSPQNQERMIYKKSGLKKMEKTGFPTV
                     NLVLREDGFDLYGSNRAEEQMHYQYTALSEILELERLILLKTADGGYQFVAKKAFASQ
                     EEQEAFKTFLQEKMEDAKAHPENYKLENEEDEAERERSSRVWEEGYVVRNKNTEGLGK
                     IGQMAHILAPSDGEEESSGTEEPAAPETAEIQEEE"
     gene            complement(19475..20224)
                     /locus_tag="ACZPCR_00135"
     CDS             complement(19475..20224)
                     /locus_tag="ACZPCR_00135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006778603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HIR1229330.1"
                     /translation="MNDKHSNHIKAFLEYSCRTAADLLFPRRCPVCGGVAMPKGRLIC
                     PACLKQLSFVSSPACMKCGKEIGSREQEYCADCIRRKKSFTRGFALLNYDSRAAVSMA
                     AVKYHNKREYLDFYARAAALRFEKQFRQAGIQVIVPVPVHASRLKTRGFNQAAVLAEK
                     LSAELGIPWEELLIRVKKTDPQKSLGSAERLKNLRGAFEAEQEAGKWERVLLVDDIYT
                     TGSTAEICSRALLKTGVKQVFVFAVCIGHGA"
     gene            complement(20241..22619)
                     /gene="recD2"
                     /locus_tag="ACZPCR_00140"
     CDS             complement(20241..22619)
                     /gene="recD2"
                     /locus_tag="ACZPCR_00140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SF1B family DNA helicase RecD2"
                     /protein_id="HIR1229331.1"
                     /translation="MASVKGFVEKIKYRNEENGYTVLSLTGSDDGEEYILVGNFSFIG
                     EGELLEASGHMTEHPVYGEQLSVESYEIKPPEDTVSMERYLGSGAIKGIGAALASRIV
                     KKFKKDTFRIMEEEPERLAEIKGISEKMAMSIGEQIEEKRDMRQAMMFLQDYGVSMNL
                     AAKIYREYGPAMYGIIKQNPYKLADDIPGVGFKMADEIAARAGILTDSDFRIKSGILY
                     TLFRASGNGHTYLPKEILTAQAAELLGVDPEEIENRLMDMQMEKRLVVKRSREETGRE
                     QAAHEEPAKEAEELPGSLDGDGEAWEEQTDQGRQLVYASQYYYTELNTAKMLHDLNIT
                     GDQPEESIRKSLKTIQEQEHIELDELQVQAVIEAVNCGLLIITGGPGTGKTTTINTII
                     RYFELGGLDILLAAPTGRAAKRMTEATGFEARTIHRLLELSGAPVEEKTGDAGERSKM
                     ANAGMRFERNEENPLDADVIIIDEMSMVDIHLMHSLLRAVSVGTRLILVGDVDQLPSV
                     GPGNVLRDMIESQCFHVVKLTRIFRQAAQSDIVVNAHRINEGGQIPLGKRSQDFLFIR
                     QEDPNAIVRSIITLVREKLPGYVHADTFDIQIMTPMRKGALGVERLNEILQKYLNPPS
                     PEKKEKESGGTIFRTGDKVMQIKNNYQMEWELRNRYGVPVDKGSGVFNGDVGIIREIN
                     TFSELMTVEFDEGKMAEYSFKQLEELELAYAITIHKSQGSEYPAVVLPIYPGPRMLMT
                     RNLIYTAVTRAKSCVCLVGIPQVFQSMVDNASQQKRYCGLKDRIQEIEESLI"
     gene            complement(22628..23632)
                     /gene="mreB"
                     /locus_tag="ACZPCR_00145"
     CDS             complement(22628..23632)
                     /gene="mreB"
                     /locus_tag="ACZPCR_00145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003502652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreB"
                     /protein_id="HIR1229332.1"
                     /translation="MMMPTDIGIDLGTASILVYIKGKGVVLKEPSVVAIDRDKNEIKA
                     IGEEARLMIGRTPGNIVAVRPLRQGVISDYTVTEKMLKYFINKAVGKRTLRKPRISVC
                     IPSGATEVERKAVEDATYQAGARDVTIIEEPVAAAIGAGIDISKACGNMIVDIGGGTA
                     DIAVISLGGTVVSTSIKIAGDDFDEALVRYMRKKHNLLIGERTAEEIKINIGAAYQRP
                     EMLTMEVRGRNLVTGLPKTIVVTSDETLEALREPALQIVDAVHNVLERTPPELAADIF
                     DRGIVLTGGGALLSGLDALIEEKTGITTMIAEDPLTAVAIGTGKFIEFLHGEGSKNFD
                     "
     gene            complement(24033..25061)
                     /locus_tag="ACZPCR_00150"
     CDS             complement(24033..25061)
                     /locus_tag="ACZPCR_00150"
                     /EC_number="3.5.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004067 - asparaginase activity [Evidence
                     IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HIR1229333.1"
                     /translation="MKRILLIATGGTIASVQTENGLAPASTAEELLSYIPEAGKFCEV
                     SVRQLFSLDSTNVQPEHWIRISQEIREEYSRFDGFVITHGTDTMAYSAAALSYLIQNS
                     EKPIILTGSQKPISVPITDARKNLMDSLRFASRDGVRGVYLVFDGKAILGTRARKIRS
                     KSYSAFESINYPVAAFIDENRIIQYVDGESRDGTVRFYENLKPSVFVLKLIPGMEPEI
                     LQYIGERYDAIIIESYGVGGIPFYNKRNFLSGLENLTKKGKIVVIATQVMLEGSDAEV
                     YEVGYKAVNSYNVLQAYDMTVEAAAVKLMWIMGQTRDFETVKKMFYTKVSQDILAGAL
                     PGETAGAP"
     gene            complement(25058..26206)
                     /locus_tag="ACZPCR_00155"
     CDS             complement(25058..26206)
                     /locus_tag="ACZPCR_00155"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229334.1"
                     /translation="MQKKICPICERPLTGSGYCRLCRKLVFKPLIREVDYYLNETRPG
                     QQTALNERNGGRSQTALEVSEKDFREKTADFYQDMKQKSGRGAQKQKTSRPPQKASGK
                     KETVWNEPLQEKSAKKADGKGSKMKPGIVAAFLIILGVAVQFISWSVDFMADRGGGSR
                     LVQEEEPQNDVWDWEAEIQEEDVWDDGEITIEEDTGSLEWEELDDEEVKAAGVRCNGE
                     THFEIRFIDVENLVKEEAYALGLEPHMSLDSYNNRYDEGGEIREFYDTYRTYAMWDEN
                     KELELAVTISSDTATGEVHFIAVNSHNEASNQAAVQMMTALADLAAGQEGTLSENELS
                     DALDSLEYVEKPEYNYYIFADIYIGEDSAYSLQIGPLYNWDEEEGNIV"
     gene            complement(26270..27829)
                     /locus_tag="ACZPCR_00160"
     CDS             complement(26270..27829)
                     /locus_tag="ACZPCR_00160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004222789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HIR1229335.1"
                     /translation="MSILNVEHLSHGFGDRAIFHDVSFRLLKGEHIGLIGANGEGKST
                     FMNIITGKLQPDEGRVEWAKRVRVGYLDQHAVLEKGMTVREVLKNAFSFLFELEEQMN
                     GICDRLGEAPEGEMESMMEELGTIQDLLMVHDFYTIDAKVDEVGRALGLADIGMEKDV
                     TELSGGQRTKVLLGKLLLEKPDILLLDEPTNYLDEQHIEWLKRYLQEYENAFILISHD
                     IPFLNSVINIIYHMENQRLDRYVGDYDKFREVYEVKKAQLEAAYKRQQQEIAELQDFV
                     ARNKARVSTRNMAMSRQKKLDKMDVIELAKEKPKPEFHFLEARAAGKCIFETEDLVIG
                     YDQNEPLSKPLNLYMERGEKIALVGANGIGKTTLLKSILGLIPALSGKAVLGDYLEIG
                     YFEQEMAPGNTTTCIEEIWKEFPSYTQYQVRSALAKCGLTTKHIESQVRVLSGGEQAK
                     VRLCKLINRETNLLLLDEPTNHLDVDAKDELKRALKEYRGSILLICHEPEFYSDVVTK
                     VWDCREWSLRI"
     gene            complement(27902..29032)
                     /gene="nspC"
                     /locus_tag="ACZPCR_00165"
     CDS             complement(27902..29032)
                     /gene="nspC"
                     /locus_tag="ACZPCR_00165"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004844802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0045312 - nor-spermidine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HIR1229336.1"
                     /translation="MKRETAVKTPYFLVDEERLVKNLELLKEIQEETDCRILLAQKAF
                     SGFFAYPLMRRYLAGTTASGLCEARLGKEEFGGETHVFSPAYREDEFEELLSYADHFV
                     FNSPAQLRRHAGRAKQAGKSVGLRVNPECSTQEGHAIYDPCAPGSRLGTVKEQFDEEL
                     LPLLDGLHFHTLCEQNSDDLETTAQAFEEKFGRYLGQMKWVNFGGGHHITREDYDVER
                     LKRVIRHFREQYDVEVYLEPGEAVVLNAGFLVSSVLETMKNGMNIAILDTSAACHMPD
                     VLEMPYRPPVLSSGMPGEKEYTYRLAGPTCLAGDVIGDYSFDHPLAEGEQVVFGDMAL
                     YTMVKTNTFNGMLLPSIVWKNRDGEEILIKEFGYEDFKGRLG"
     gene            complement(29169..30371)
                     /locus_tag="ACZPCR_00170"
     CDS             complement(29169..30371)
                     /locus_tag="ACZPCR_00170"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA];
                     GO_process: GO:0009085 - lysine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HIR1229337.1"
                     /translation="MGKALIIGCGGVASVAVHKCCQNSGVFEEICIASRTKSKCDALK
                     EKLQRTTSTKITTAQVDANDVDALIALINEVKPDVVLNLALPYQDLTIMDACLATKTH
                     YVDTANYEPEDTAKFEYSWQWAYREKFEQAGITALLGSGFDPGVTSVFSAYALKHEFD
                     EINYIDILDCNGGDHGYPFATNFNPEINIREVSAKGSYWEDGHWVETEPMEIKRVYNF
                     EEVGEKDMYLLHHEEIESLALNIPGIKRIRFFMTFGQSYLTHLKCLENVGMTSIEPIM
                     YEGKEIIPLQFLKAVLPDPSSLGPRTKGKTNIGCIFRGKKDGKDKTYYLYNICDHQEC
                     YKEVGSQAVAYTTGVPAMIGAMMVMTGKWQKPGVYNMEEFDPDPFMDALNKWGLPWRE
                     SHDLVLVD"
     gene            complement(30413..31315)
                     /gene="speB"
                     /locus_tag="ACZPCR_00175"
     CDS             complement(30413..31315)
                     /gene="speB"
                     /locus_tag="ACZPCR_00175"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008783 - agmatinase activity [Evidence
                     IEA];
                     GO_process: GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HIR1229338.1"
                     /translation="MSEEKRQAGTLSPNVSVYMGFDAEFEEADTVLFGAPFDSTTSFR
                     PGTRFGSEAIRRESYGLETYSPYQDRDLEDSFIMDSGDLELRFGDPKQALADIEERTA
                     FILEAGKRPFMLGGEHLVTLGSFRAVHKKYPDAAIIHFDAHTDLREDYLGEPLSHACV
                     IRRCWDLTGDGSIFQFGIRSGERWEFQWAKEHTFLNPFDFTGLEETLERLRGRPVYFT
                     VDLDVMDPSVFPGTGTPEPGGVTFDQLRRAVTLVCDRANIVGCDVNELSPHYDLSGAS
                     TAAACKIVREMALALQRQDQEKHR"
     gene            complement(31417..32268)
                     /gene="speE"
                     /locus_tag="ACZPCR_00180"
     CDS             complement(31417..32268)
                     /gene="speE"
                     /locus_tag="ACZPCR_00180"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008974988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HIR1229339.1"
                     /translation="MEYWFSEEQTPNVKLSIRVDRQLYSGKSEFQRIDVFDSPEFGRF
                     LTLDGYMMLTEKDEFIYHEMITHVPMAVHPAVKNVLVIGAGDGGVIRELTRYPEIEHI
                     DLVEIDELVVEVCKKYLPKTSCRLDDPRLSIHYEDGVRFVRSCEDKYDLIIVDSTDPF
                     GPGEGLFTREFYGSCFKALHEDGIMVNQHESPFYPADAVACQRAHKRIVESFPISRVY
                     QAHIPTYPSGHWLFGFASKKYHPLKDLREAAWNLKGLSCNYYTTTLHKGAFYLPAYVE
                     QMLEEVE"
     gene            complement(32325..33782)
                     /locus_tag="ACZPCR_00185"
     CDS             complement(32325..33782)
                     /locus_tag="ACZPCR_00185"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018594872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HIR1229340.1"
                     /translation="MRELTQDNAPIFEALERFKHMRVVPFDVPGHKRGRGNPELVNLL
                     GEKCVGIDVNSMKPLDNLCHPVSVIAEAERLAAEAFGAAHAFLMVGGTTSAVQSMILS
                     VVKRGDKIILPRNVHRSVVGALILCGAVPVYVNPECDMRLGIPLGMKVEQVEKAIKEN
                     PDAKAVLVNNPTYYGICSNLREIVRLAHSHGMLCLADEAHGTHFYFGENLPVSAMAAG
                     ADMAAVSMHKSGGSLTQSSLLLIGPAMNEGHVRQIINLTQTTSGSYLLLSSLDISRRN
                     LALRGKEAFAGVVRMADDARKEINAIGGYYAFSKELINGDSIYDFDVTKLSVHTLDIG
                     LAGIEVYDLLRDEYDIQIEFGDLGNLLAYLSIGDRQRDIERLVSALAEIRRRFGTTGT
                     GMAVPEYIDPQVAVSPQDAFYADKISLPIEETAGYICSEFVMCYPPGIPILAPGERIT
                     EEILAYIAFAKEKGCTMTGPEDADILRLNVIKGSN"
     gene            complement(33827..34597)
                     /gene="speD"
                     /locus_tag="ACZPCR_00190"
     CDS             complement(33827..34597)
                     /gene="speD"
                     /locus_tag="ACZPCR_00190"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004014 - adenosylmethionine decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HIR1229341.1"
                     /translation="MGEKMKLYGFNNLTKSLSFNIYDVCYAKTAREQKDYIAYIDEQY
                     NSERLTNILTSLTDMIGARVLNIAKQDYEPQGASVTILIAEKTMVPAGDMQLAHLDKS
                     HVTVHTYPEYHPETCLATFRVDIDVATCGEITPLSTLDYLIRSFDSDIITMDYRVRGF
                     TRDVDGRKLFMDHHVASIQDYIDPEIMRRYDAVDINVYEANLFHTKMMVKEVDLQNYL
                     FKTDIYELPPTVRLEIMHSLRREMIEIFSGRNIYHPGL"
     gene            complement(35251..36510)
                     /locus_tag="ACZPCR_00195"
     CDS             complement(35251..36510)
                     /locus_tag="ACZPCR_00195"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003509687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HIR1229342.1"
                     /translation="MNRDYPVNNKEDFVIELPSQVEWILKKLRDRGYEAFAVGGCVRD
                     TILNRKPGDWDITTSARPEQVKAVFGKTVDTGLQHGTVTVIRDHVGYEITTYRIDGEY
                     EDGRHPKEVEFTADLREDLHRRDFTINAMAYSHETGLVDIFGGLEDLKAGRIRCVGNA
                     MERFTEDALRIMRAVRFAAQLNFTIEEETWRALSAIAPNLSHVSKERIQTELTKTLLS
                     GNPQGVLAMEKTGMSPYMTQSFPDIFSEAQSLGIYLEERLRRSAELPAEKYFRYGALL
                     AHLGEKKTETILRELKLDNHTIRSAKTLAAFSGLPLPTEEGAVRRTMSQMEDWLFDAF
                     LIFERNLLPEKREQAEQAEKLCRRIRERGDCVRMKDMKVTGNDLMEAGVKPGKTVGET
                     LAGLFAEVLEDPQKNSREELLSMALSR"
     gene            complement(36526..37008)
                     /locus_tag="ACZPCR_00200"
     CDS             complement(36526..37008)
                     /locus_tag="ACZPCR_00200"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004845963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1229343.1"
                     /translation="MVLRAYRPSDCSEVLRLFYDTVHTVNARDYTEEQLDAWADGKPD
                     AAKWNESLCAHFSLAAEADGILAGFGDIDETGYLDRLYVHRDFQGMGVGTALCQALEQ
                     EAVRAVRQTKPDASVCITTHASITARPFFEARGYQVQREQQVERKGVLLTNYIMEKRV
                     "
     gene            complement(37415..38848)
                     /gene="proS"
                     /locus_tag="ACZPCR_00205"
     CDS             complement(37415..38848)
                     /gene="proS"
                     /locus_tag="ACZPCR_00205"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HIR1229344.1"
                     /translation="MAKDKKLVEAITSMDVDFAQWYTDVVKKAELIDYSSVKGCMVIK
                     PAGYAIWENIQRELDRRFKETGVQNVYMPMFIPESLLQKEKDHVEGFAPEVAWVTHGG
                     LEPLQERMCVRPTSETLFCDFYAKDIQSYRDLPKLYNQWCSVVRWEKTTRPFLRSREF
                     LWQEGHTAHATAEEAEERTEQMLNLYADFCEEVLAMPVVRGRKTDKEKFAGAEATYTI
                     EALMHDGKALQSGTSHNFGDGFAKAFGIQFSDKDNKLKYVHQTSWGMTTRLIGAIIMV
                     HGDDNGLVLPPRIAPTQVVIVPIRQQAEGVLDKAYQLKDVLSGFSVKVDDSDKSPGWK
                     FSESEMRGIPVRVEIGPKDLENNQAVLVRRDTHEKMTVSLDEIKEKVTELLDTIQHDM
                     FERARAHRDAHTYTAVNLDEMKDLADNKPGFIRAMWCGCQECEDKLKEIAGVTSRCMP
                     FKQEKVADTCVCCGKPAAKMVYWGKAY"
     gene            39461..40597
                     /gene="alr"
                     /locus_tag="ACZPCR_00210"
     CDS             39461..40597
                     /gene="alr"
                     /locus_tag="ACZPCR_00210"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: protein motif:HMM:TIGR00492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HIR1229345.1"
                     /translation="MDLTCYNSYYEVNLSVLEENFKKISRFIAPAQVIPVLKADAYGM
                     GALEIARVLTERCGCRTLACSQTYEGLVLREGGITDAEILIMGPVLHDTLPHAVRWDM
                     QIPLFTPERVRSLSREAARQGKTVKAQIKIETGLNRIGAWPGKQLQEVIDALHQCPNI
                     QVVGAFTHFAQAETPEDAFTKEQFAVFKEGVAQLEEAGFHLSYIHCCNTGASEWYREA
                     LDFSTHIRAGSLVLGYSDIADGSNPMGLREMLSWRTTVSFIRHVEPGETVSYDRLFKA
                     EKPTDIAVVSVGFADGILCAMARSHGPVLVNDQRAHYVDTCMDQCFVDVTGLDCRVGD
                     PVTLWGYSPSGRAFLSPQELSKYGQVYTAYTSQRPNRIGRIYIG"
     gene            40616..41428
                     /gene="yqeC"
                     /locus_tag="ACZPCR_00215"
     CDS             40616..41428
                     /gene="yqeC"
                     /locus_tag="ACZPCR_00215"
                     /inference="COORDINATES: protein motif:HMM:TIGR03172.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium cofactor biosynthesis protein YqeC"
                     /protein_id="HIR1229346.1"
                     /translation="MPSSFVIAAVGSGGKTTALKELARQAALRNQNGSVLLAASTHMY
                     PVLPPESRVFLRDPDEKTLRRELAEPGIVCAGRTARDQKISALEPELFSAALQTASVI
                     LCEADGSRRLPLKLHSEREPVLPARTDVCLITAGLSALGKEAGSCIHRYELNPVWKSR
                     PDTRIGGEELALCVLDAVSSVMLPTEQDGRLCAPKSRGFGVRLSKKRIRILLNQDDCL
                     FCPESNGSSLAALRKEASAAVRMLEEHGLSCRMGSLLEDSSFLWDWIVSSGR"
     gene            complement(41425..42633)
                     /gene="yqeB"
                     /locus_tag="ACZPCR_00220"
     CDS             complement(41425..42633)
                     /gene="yqeB"
                     /locus_tag="ACZPCR_00220"
                     /inference="COORDINATES: protein motif:HMM:TIGR03309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent molybdenum cofactor
                     biosynthesis protein YqeB"
                     /protein_id="HIR1229347.1"
                     /translation="MKKQLNVQSSIRLKGDQKAFGPGIASLLEGVARLGSLRKSAADM
                     DMSYSKAWTMIKNCERELGISLLNKKIGGKGGGGADLTGEAESLLKRYRAFEREAAVR
                     LDTLAGKYFPEYIKNTENTKFFEAGPWILVRGAGDLATGVILRLYRSGFRVAALECKN
                     PSAIRRRASFCEAVWTGETQVEGVSCRLAQTPEQAEKIWAQGQIPLLIDETAACVHKL
                     HPAAVIDVILAKRNLGTSRSMAPITIGAGPGFTAGQDVDAVVETMRGHFLGRVIWEGQ
                     AIPNTGIPGKIQGFGAERVIHAPEEGRLSFVKDESGNMVEIGAMVKKGQTIAMIEGTP
                     VKASLDGVLRGLIQEGFPVKKGLKIADIDPRPEQAAFCGTVSDKANAVAGGVLEALLG
                     LAASRQIRLF"
     gene            complement(42630..43457)
                     /locus_tag="ACZPCR_00225"
     CDS             complement(42630..43457)
                     /locus_tag="ACZPCR_00225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002601803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HIR1229348.1"
                     /translation="MDLYTWYQWLTFFYFYSFLGWIFESSYVSVKQRRLVNRGFLRIP
                     LLPLYGSGALMMLIVSRPFQDSLLLTWLSGFTGATVLEYGAGWAMEQLFKVRYWDYSS
                     QRFNFHGYICLSSSVAWGFLTIFMTDLIHRPIEKLVCGIPVILDLLLILPVTAVFLQD
                     AFASIREALDFGHSLERANQIRQELDGLRVQTALLKMDAGDRIEEKRAELESWLKERE
                     EALLAIRDRRKQFLQSALRANPTMVSHKYAEELKEMMKGLSENGKNRSSQRGRRKEQ"
     gene            43704..44729
                     /locus_tag="ACZPCR_00230"
     CDS             43704..44729
                     /locus_tag="ACZPCR_00230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HIR1229349.1"
                     /translation="MKLMRTEDAAGQVLCHDITQIIKGVTKDAVFRKGHIIQPEDIPV
                     LLSVGKEHIYIWENDETMLHENEAAGILCQLCQGPGMRASEPKEGKIELTAKHDGLFL
                     ADVERLRRINSLGEMMIASRPGGFPVKAGDRLCGTRVIPLVIKKEAMERARQAAGPKP
                     LFSLLPFKKKSFGVVTTGSEIFHGRIQDTFTPVIEEKLAEYGCAMEAHEICDDREEEI
                     IKAIQTMADRGIDMIFCTGGMSVDPDDRTPSAIRKSGASIVSYGAPVLPGAMFLVSYL
                     PDGRPVCGLPGCVMYARRTIFDLVLPRLLADVPVTSQWLAGLGHGGLCLSCPECHFPN
                     CGFGKGV"
     gene            44806..45318
                     /gene="moaC"
                     /locus_tag="ACZPCR_00235"
     CDS             44806..45318
                     /gene="moaC"
                     /locus_tag="ACZPCR_00235"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012199507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0061799 - cyclic pyranopterin
                     monophosphate synthase activity [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HIR1229350.1"
                     /translation="MNFTHIDHQGNAVMVDVSQKAFTARTASACGRIRMSRECYQAVE
                     SGTAKKGDVLGAAQIAGIMGAKQTADLIPLCHRLNLSKASVSFRLLPELPGVEAVCTV
                     KCTGQTGVEMEALTGVNIALLTIYDMCKAIDKRMVMKDIHLVEKHGGKSGDFSFDGER
                     KDGAAEASYV"
     gene            45311..46300
                     /gene="moaA"
                     /locus_tag="ACZPCR_00240"
     CDS             45311..46300
                     /gene="moaA"
                     /locus_tag="ACZPCR_00240"
                     /EC_number="4.1.99.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009267884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HIR1229351.1"
                     /translation="MCNSICGSLRDSYGRTIDYLRISITDQCNLRCRYCMPGQDGISS
                     PCRLMTFGEILAAARAAARLGIRSVKITGGEPLCRPGCPDLIGRLKEIPGIRQVTMTT
                     NGLLVSRYLDELLNAGLDGINISLDTLNEEQFRQITRRNFPLSQVLEAIKRCSEKLPT
                     KINAVLLPETEDQLIPLARLACFLPVSVRFIEQMPLGGERPSKASRGWDSVLARLKKE
                     WPDLSPVPERRGNGPAVYYSAPEFSEAVGLIEAVSHSFCSGCNRIRLTCEGQLKPCLC
                     YGDSLDLTPALKSKNEEELLALFLKAVRNKPKAHCFREASEVSERRYMSQIGG"
     gene            46340..47317
                     /locus_tag="ACZPCR_00245"
     CDS             46340..47317
                     /locus_tag="ACZPCR_00245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004077673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HIR1229352.1"
                     /translation="MGTVLAVCRSSVRGIQKTNEQSGWFETEWGIRGDAHAGRWHRQV
                     SLLSADRIARFNEKGAGVGPGDFGENLVVEGIDFSSLPVGTWLRCGDVLLEITQIGKE
                     CHSHCAIYHKMGDCIMPREGVFARVLEAGQISIGDQMSVVPRKEPLPFQAAVITLSDR
                     CSSGEREDESGPAIEKRLIEEGYQIIERLVLPDDRAALEKELIRLCDQRTPDLILTTG
                     GTGFSSRDITPEATLAVAERPAPGIAEAIRAASMEITRRAMLSRAVSVIRGKTLIVNL
                     PGSPKACMESMDVFMDQLPHGLSLLRGSVMDCGRRQEAPDAGRGRSGRI"
     gene            47361..48185
                     /gene="modA"
                     /locus_tag="ACZPCR_00250"
     CDS             47361..48185
                     /gene="modA"
                     /locus_tag="ACZPCR_00250"
                     /inference="COORDINATES: protein motif:HMM:NF024921.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA];
                     GO_function: GO:0030973 - molybdate ion binding [Evidence
                     IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HIR1229353.1"
                     /translation="MKISKKRLMFPLLLAAAAAVFSGCSSLLSGDPDGSSSESSELTV
                     FAAASLTEALEEIAEEYQKAEPDVSLIFNFDSSGTLKTQIREGAVCDLFLSASPKQMD
                     QLETESHSLLPESRIDLLENQVVLVTPKENEKNVDSFDSLAEHLKAGDILLAMGNSDV
                     PAGQYAEKLLSWYGLDMRELESKGLVTYGSNVKEVAAQVSEGSADAGIIYSTDAFSAG
                     LPVLDRASEEMCGKVVYPASVLKSSGCQKEAQDFLDFLSGPKAQAVFERIGFSMAE"
     gene            48196..48888
                     /gene="modB"
                     /locus_tag="ACZPCR_00255"
     CDS             48196..48888
                     /gene="modB"
                     /locus_tag="ACZPCR_00255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HIR1229354.1"
                     /translation="MDWYPLWNSLRIAAVSSVLVFFSGIGAAYYAAKLPRLLKGFLDV
                     FLTLPMVLPPTVVGYFLLLLVGNRRPLGMALENLGLQLVMDWKGGILAAFAVSFPLMY
                     RTARGAFESFDETLAQAGKTLGLSNAFIFWRIRMPVCRQGILAGAVLAFARALGEYGA
                     TSMLIGYTPGRTATISTTVYQMWRTGDDRQAFLWVFVNLAISAAVLLAVNGLEQKDRQ
                     KKKGAPVAECND"
     gene            48869..49906
                     /locus_tag="ACZPCR_00260"
     CDS             48869..49906
                     /locus_tag="ACZPCR_00260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018597434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015419 - ABC-type sulfate transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HIR1229355.1"
                     /translation="MLSVTIEKRLGNFLLKTDFETEEPITGLLGASGCGKSLTLKCIA
                     GLEQPDRGRILLDGVVLFDSDAGICLPPQKRQVGYLFQSCALFPHMTVKQNILCGMQK
                     EKDRSRRQESLCRLSRLLRLESVMDLKPGSLSGGQAQRTAIARILASRPRLLLLDEPF
                     AALDSYLREQLQAELKELLLSLECQTVLVTHSRDEAFLLCSRLAVMDRGTISAAGGVK
                     ELFDRPKTVAAARLTGCKNIAAARKTGDFTVEVPGWGICLTASSPIPDGLRAVGVRAH
                     SFNPGIATNRFPAVLCSRMEEPFEQLFLFRFQGQSPDSPPLWWRLPKEQAPDFFPAAL
                     GVSLEQVLLLT"
     gene            49992..50990
                     /locus_tag="ACZPCR_00265"
     CDS             49992..50990
                     /locus_tag="ACZPCR_00265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="XdhC family protein"
                     /protein_id="HIR1229356.1"
                     /translation="MIKDIISSAAGGRPLVLVSVVSSKGSTPRSAGAMMTVDESGLLA
                     GTIGGGALEGRCLEEAVSFLKRLGSGGKKARPSGFLRSFSLNNSQAGDLGMICGGSTD
                     VLFTPVLPEDRGAFREALSCMEAGEASFLLLPLDGSAPAFQRQPGDGSQSLRKPCLCT
                     ADSRSCLSIPLTASSRIFLLGGGHVSLDLSLLLDRLEFPYFVIDDREEFASRERFQKA
                     AKTIVIPLEPALLSEALTKTLAPRETDAFCIMTRGHSGDEAALRFALSTKASYIGLMG
                     SRKKREAIFSRLEQDGFPDVRSRIITPIGLDIRAQTPAEIAVSVAAQLIAWRAGLS"
     gene            complement(50983..51252)
                     /locus_tag="ACZPCR_00270"
     CDS             complement(50983..51252)
                     /locus_tag="ACZPCR_00270"
                     /EC_number="3.6.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009214389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003998 - acylphosphatase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HIR1229357.1"
                     /translation="MVRKHIFFSGWVQGVGFRYRALYAARAMGLTGWVQNLWDGRVEM
                     EVQGEPEKIERLIARLKEGTFIVIDSMTMADVPLKEGEGEFRVFS"
     gene            complement(51245..51856)
                     /locus_tag="ACZPCR_00275"
     CDS             complement(51245..51856)
                     /locus_tag="ACZPCR_00275"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012514.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016817 - hydrolase activity, acting on
                     acid anhydrides [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HIR1229358.1"
                     /translation="MKSLKNRIPRPVGWNARRDCAVVIPIIREQGQYAVLFERRAGSL
                     KTQPGEICFPGGSMEPGESPWEAALRELSEELLIQPDQAEFLMACDYLEIPAGFSVYP
                     FLAELKGYQGTFSEEETEEIIKIPLQWFFDHAPLHRTAKILTVPEEPFPYDLIPQGRD
                     YRWREGRYEVLFYQYGDLVIWGMTAKMMKSCVDTLQEEGILHG"
     gene            complement(51853..52584)
                     /locus_tag="ACZPCR_00280"
     CDS             complement(51853..52584)
                     /locus_tag="ACZPCR_00280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016298615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HIR1229359.1"
                     /translation="MKIKLHYEEKGTGQPMVLLHGNGEDSSYFKNQIEYFSKKYRVIA
                     VDTRGHGKSERGTAPFTLRQFARDLKSFLDEMGLRRIILLGFSDGGNIALIFTILHPQ
                     YVDRLLLNGANLNPWGMKAGVFKNIYLAYWKACLRIAKGERKKHKTEDDRYLLEKARK
                     KKELMGLMIKEPHIRPVYLKTMRKPVLVIAGTKDMIRTGHTKKIHRLIPGSRLCLLNG
                     THFIASENSLEFNQAAEWFLEGGNR"
     gene            complement(52581..53675)
                     /locus_tag="ACZPCR_00285"
     CDS             complement(52581..53675)
                     /locus_tag="ACZPCR_00285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003502591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HIR1229360.1"
                     /translation="MPELSKKQRKALVILSVTGGVYISFKYFLPLILPFAAAYLAALV
                     LRPGAAWIEKRLQINIRGRRYSVPIGVIGGAELLLLAAAAGLLLFCGSRRLMEEANEM
                     IHAAPGWMMRLDQWLTSLCRTAEVFCRLREGALVQAAREMITAMTRTLRQAAMSSLAV
                     NSVAALSFCARAFVMAAVFFMAAVLSLQEMDEMKRRRRQSMFSREFALFGRRLIMTGS
                     AWLRTQLVIMLVTACLCALGLLLIRNPYSILLGAVIGVLDALPLFGAGAVLIPWSVVA
                     MAQGHFYQGGVLALLFLICCLTREFLEARLMGGKMGLSPLETLTAIYVGMKLFGILGM
                     LLGPIGLLIIEDLVEEYGEKRADAQKEDER"
     gene            complement(54008..54787)
                     /locus_tag="ACZPCR_00290"
     CDS             complement(54008..54787)
                     /locus_tag="ACZPCR_00290"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006778564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HIR1229361.1"
                     /translation="MIKILYEDDAVLVAVKPAGLESQASRKLEPDMVSEIKNYLLRSR
                     RRKERQEGRGLSTTMSTNSSTQAQEPYVGVIHRLDKPVSGVMVYAKTKEAAAFLSKEV
                     QAHRVTKIYHAVICGKPVDNVGNFVDKLSMNRENNYSRIVDNSDPEGKTAELSYRVIG
                     ENKEKGLTLVEIHLKTGRHHQIRVQFAGHGLPLWGDAKYNPAVSMEGGKGPLALAAVS
                     LSFTHPVTKEPVTFSMKPQGGAFRLFPAASCQPGESSAVSQ"
     gene            54988..55656
                     /gene="trhA"
                     /locus_tag="ACZPCR_00295"
     CDS             54988..55656
                     /gene="trhA"
                     /locus_tag="ACZPCR_00295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013271119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PAQR family membrane homeostasis protein TrhA"
                     /protein_id="HIR1229362.1"
                     /translation="MKCIADLHIKDPGSALTHFIAFVGSAAAAAPLLMKAAAEPDASR
                     LQIAALAVFIVSMILLYAASTVYHTLDISEKVNRLLRKLDHMMIFILIAGTYTPICLI
                     VLGNRSGFLLLALVWAIAAAGILINAFWISCPKWFSSLIYISMGWVCVTAFREIISAL
                     PPAAFSWLLAGGIIYTAGGVIYALKLPIFNSRHKNFGSHEIFHLFVMGGSLCHYVVMY
                     AFVA"
     gene            complement(55634..56518)
                     /gene="larE"
                     /locus_tag="ACZPCR_00300"
     CDS             complement(55634..56518)
                     /gene="larE"
                     /locus_tag="ACZPCR_00300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HIR1229363.1"
                     /translation="MDFTANQNKKQQLQEKEKQLAAVMDEYGKEPVCLAFSGGVDSSL
                     LLKLACAAARRHGTKVWAVTFDTMLHPVCDLENARKVAKEMDADHVVLSVDELEQEEL
                     RNNPVNRCYLCKRRLFLRLQEFAGEKGCSLLLDGTNADDLEEYRPGLAALRELGVKSP
                     LASCGLTKKEVKALAGKYGISAASRPSAPCMATRLPYGARLDYDLLKRIEEGEEFLNR
                     ELFSEEKPGNVRLRVHGDTARLETDAGQFAAVLEKRERIAKRLKELGFTYITLDLEGF
                     RSGSMDVKVRASTPQTHT"
     gene            complement(56535..57989)
                     /gene="larC"
                     /locus_tag="ACZPCR_00305"
     CDS             complement(56535..57989)
                     /gene="larC"
                     /locus_tag="ACZPCR_00305"
                     /EC_number="4.99.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003502568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
                     /protein_id="HIR1229364.1"
                     /translation="MEKEKILYLECYSGISGDMTVGALLDLGASRERLMKELEKLGIG
                     GYHLHFGRTQKCGIDAYDFDVHLEEEEHDHGHDHDHNHHHDHEEHDHGHSHAHDHHED
                     HDHDHHHHGDHGRHHHEDHSHTHDHGHGHDHHHSHVHRNVHDIYQIIDRLEDEEARRL
                     AKEMFRLVAEAESRAHGLPVEQVHFHEVGAVDSIVDIVGTAVCIRDLGISRVAVSPLS
                     EGRGYVKCQHGVMPVPVPATAGIAAACGLTLRLTDNEGEMVTPTGAAIAGCLRTEQEL
                     PERYIIEKIGVGAGTKDFKNANILRAMILVPEEEEQTEKEQKQSGKAEPGFSGTQEPD
                     SMYVIETNIDDCSGEALGFLMECLLEEGAADVWYTPAVMKKSRPAYVLHTLCRRAQIE
                     DMEGLIFSHTTTIGIRRYPVERTVLNRRVEEMDLPLGKLAVKMCSFRGEERFYPEYES
                     IARISRETGMGFAEVYHLARSQAEEAAGKHEHRN"
     gene            complement(58059..58817)
                     /gene="larB"
                     /locus_tag="ACZPCR_00310"
     CDS             complement(58059..58817)
                     /gene="larB"
                     /locus_tag="ACZPCR_00310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009460973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HIR1229365.1"
                     /translation="MDIKEMLHQVRDGALSVEEAEKQLKNLPYEDLGYAKLDLHRKLR
                     SGFPETVFCQGKPDEFLAEIFKKLYQENGEVFGTRASKEQYELVKKAVPQIEYDPISR
                     ILSASRPESRRQQTGCVAVCTGGTADIPVAEEAARTAEFFGCRAERIYDVGVAGIHRL
                     LAQRERLAKANCIIAVAGMEGALGTVIAGLVENPVIAVPTSVGYGASFHGLSALLTMI
                     NSCANGIAAVNIDNGYGAGYLAAQINRLAERKAE"
     gene            complement(58857..59456)
                     /locus_tag="ACZPCR_00315"
     CDS             complement(58857..59456)
                     /locus_tag="ACZPCR_00315"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002600813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1229366.1"
                     /translation="MKLKAEGISFRYEKRGRQILTDCSIEVDSGERIGLMARSGSGKT
                     TLCKILAGYEKPEGGSVTLDGAPLSSFRGRCPVQMVFQHPEQSVNPRWRMKEVLREGG
                     VSPGEMTERLGIREEWLTRYPDELSGGELQRFCIARALGEETRFLLADEITAMLDLAS
                     QKEIWLFLLEELERRNIGLIAVSHSEKLLEEVCHRVIGW"
     gene            complement(59446..60285)
                     /locus_tag="ACZPCR_00320"
     CDS             complement(59446..60285)
                     /locus_tag="ACZPCR_00320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HIR1229367.1"
                     /translation="MNEKRKPLLAVKNLSVSFQEERGFKKRQIQPIRDLSLEICAGEI
                     TALAGASGSGKSLLAQAVMGILPEQAAAEGTIEFQGQELTKEYLRALRGREIALIPQG
                     VNGLDPLMRAGNQIRKGRKDLASFKRMEELLDRYGLPGETADKYPFELSGGMARRVLT
                     AGAMMEGPRLVIADEPTPGLDAEAALQVMGHFREMADQGVGVFVITHDLELALQTADR
                     ILIFYEGTVAEELQMAKDEAGRPLGTLAAPPSHLYARRLFDAVPGQGKPWREEIRRKT
                     DEA"
     gene            complement(60346..61128)
                     /locus_tag="ACZPCR_00325"
     CDS             complement(60346..61128)
                     /locus_tag="ACZPCR_00325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006783096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1229368.1"
                     /translation="MWNIVISASVLLFITAAGAALSEQAGAADFARKNLPPQAGFLFG
                     TDWLGRDMFARTLAGLSLSIRLGLVTAFLSALAALVLGTASAMGKWADRAVSGLIDLI
                     MGIPHMLLLILISYACGKGFTGAAAGIALTHWPSLARVIRAEALQIRESQYVKISARL
                     GMSRLQIIRKHIAPQLLSQFMTGLILTFPHAVLHEASITFLGFGLPPEEPSVGMILSE
                     SMRYLITGKWWLALLPGLALTGTVLLFESMGRQWGRKRRIWR"
     gene            complement(61336..62319)
                     /locus_tag="ACZPCR_00330"
                     /pseudo
     CDS             complement(61336..62319)
                     /locus_tag="ACZPCR_00330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002600816.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(62341..63975)
                     /locus_tag="ACZPCR_00335"
     CDS             complement(62341..63975)
                     /locus_tag="ACZPCR_00335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003502550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIR1229369.1"
                     /translation="MKLKTWGLYLIMTVFLIGGCRHKQGGQEIEHAGNHTAELEGNQE
                     IEKTSAVVVMTTESEPESGFDPAYGWGAGEHVHEPLIQSTLTVTKEDLTIGYDLATEM
                     DVSEDGLTWTVDIRTDAVFTDGEPLTAEDVAFTYNTLKETSSVNDFTMLDRAEAEDED
                     TVVFHMKHPYSIWPYTMASTGIVPEHAYGPDYGMHPIGSGRYVMKQWDKGQQVIFEAN
                     PDYYGEAPKLKKLTVLFMEEDAAFAAVLAGQADVAYTAASYGEQEVSGYRLMACESVD
                     NRGFNLPAVPAYTDENGVKRGNDFTSDVRVRQVINLGIDRQAMIDHVLNGFGSPAYSV
                     CDKLPWYNPEAETDFDPEQAARLLDEAGWTEGADGIREKDGTRAELEILYPADDSVRQ
                     ALAMDTSNQLASLGIQASVRGVGWDTAYTDALSQPLMWGWGAHTPMELYNIYHTDEAL
                     GTAQYSPYSNETVDAYMEQALESSDLEESYELWKKAQWDGGTGASGIGDAPWIWLVNV
                     DHLYWVRDGLNTGEQKIQPHGHGWSVVNNADQWFWE"
     gene            64412..65626
                     /locus_tag="ACZPCR_00340"
     CDS             64412..65626
                     /locus_tag="ACZPCR_00340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015501 - glutamate:sodium symporter
                     activity [Evidence IEA];
                     GO_process: GO:0015813 - L-glutamate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HIR1229370.1"
                     /translation="MNFDPATSTLTLDLLATTGFGCVMVYLGKGIVRRVKAFQDWSLP
                     APVIGGLIVALILSFLKSRGIFTVQWTSTLSSHLMNLFFTCVGFGFSRTLLDRGKKFC
                     AGIALSVLLLVLLQGILGIAVASALGMHPLMGIQIGTGALAGGVGTTSAFGPVYESMG
                     AVGATEIGVAAATLGMIIGSLTGGPLAVLLIKRHNLKSDPNESAFEEDSESVFPLNAK
                     TLLSSVCMITIIAACGIPIYLLLSQIPYIEMPYFIGCLFAGAIARNVLEALHVEIRPQ
                     EVETIEHVSLDIFLAITIMTMDLTKIAGSAGPMLATLVIVSIATLLFTYFIGFRMYKS
                     DYNAACMCAGLIGMGMGSGSNAVANERAVMEKYGYSHIAWILYPAFSVLCVDIFNPLF
                     MSFAPGLMGFGG"
     gene            complement(65691..66506)
                     /locus_tag="ACZPCR_00345"
     CDS             complement(65691..66506)
                     /locus_tag="ACZPCR_00345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1229371.1"
                     /translation="MNYYTSLFKGIIEKRKLIWDLSKADFKKRFVGSYFGVIWMFIQP
                     LVTILIYAFLFGEYGFKSPPPVPGASYVIWMVPGIVPWFYFSEALNTGTNCLQEYHYL
                     VKKVVFQVEMLPIIKMISCFMVHACFLVIMVGLYLVGGHFPIITWIQVLYYSFAASML
                     ALAVTYLTSSIQVFFKDMAQIVGICLQFGMWLTPIMYHESMFTNAHPWLLPLFKLNPF
                     YYISTGFRDSMLEGHWFFERPTLTLYFWGVTFILMFLGLKVFRKLRPHFSDVM"
     gene            complement(66535..67089)
                     /gene="rfbC"
                     /locus_tag="ACZPCR_00350"
     CDS             complement(66535..67089)
                     /gene="rfbC"
                     /locus_tag="ACZPCR_00350"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002577448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HIR1229372.1"
                     /translation="MGKIKVTPCDIKGLYVIEPTVFKDERGYFVETYNQNDFKEAGLD
                     MVFVQDNQSMSVKGVLRGLHYQKQYPQGKLVRAIRGTVFDVAVDLRADSETYGKWFGV
                     VLSAENKKQFYIPEGFAHGFLVLSDEAEFAYKCTDFYHPGDEGGLAWDDPEIGVEWPI
                     EEGMELIISEKDQKWGGFKDTFRF"
     gene            complement(67342..67701)
                     /locus_tag="ACZPCR_00355"
     CDS             complement(67342..67701)
                     /locus_tag="ACZPCR_00355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HIR1229373.1"
                     /translation="MTLLLRIVLIVASVLTTVLILRKIRQSKLQIEDSLFWIGFSFML
                     ILFSVFPIVPTVLAELAGTYSTSNFIFLFVIFLLIVKLFHMTIKQSQMETRLRELVQK
                     MAIDEKEERDRAKEKED"
     gene            complement(67717..68409)
                     /locus_tag="ACZPCR_00360"
     CDS             complement(67717..68409)
                     /locus_tag="ACZPCR_00360"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009663985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1229374.1"
                     /translation="MSDLLIVIPAYNEESNIEKVVDRLIKGFPQYDYLVINDGSRDRT
                     GEICRARGYEFLDLPVNLGLAGGFQAGLKYAAKKGYRYAVQLDGDGQHRPEYLEAMMK
                     KMEEGYDIVIGSRFVGAKKPLSMRMIGSRLIEWAIRLTTGVTIKDPTSGLRMFNQNMI
                     REFAGGLNYGPEPDTVSYLIKAGARVAEIPVIMDERVQGASYLTPVKSVFYMAKILLS
                     ILLIQSFRKREG"
     gene            complement(68443..69408)
                     /locus_tag="ACZPCR_00365"
     CDS             complement(68443..69408)
                     /locus_tag="ACZPCR_00365"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HIR1229375.1"
                     /translation="MEQGTIKTVDAVIPVYRPGKSFEELLKRLSQQEYPLRRVIIMNT
                     EEQYWNTEYETAFLAAGEGKGPKLQVYHLSKAEFDHGATRDRGIRLSDADVCICMTHD
                     AVPGDARLVGNLVKALEAGEDIAAAYARQLPFEDCSVIETYTRSFNYPETSRIKSMAD
                     LKELGIKTYFCSNVCAAYRTDIYRKLGGFIKKTIFNEDMIYAAGAMKQGYRIAYAADA
                     VVFHSHNYTALEQLRRNFDLAVSQADHPEVFAGISSEGEGIRLVKRTAAFLLRKGKWY
                     LIPQLAVHSGFKYMGYFLGKRYRRLPKKVVMGLTMNKAYWDKPGI"
     gene            complement(69444..70265)
                     /locus_tag="ACZPCR_00370"
     CDS             complement(69444..70265)
                     /locus_tag="ACZPCR_00370"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009101 - glycoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family A protein"
                     /protein_id="HIR1229376.1"
                     /translation="MIEKKERKLHTFAICAYGDSPYLEECMASLACQRQKSEIICCTS
                     TPSPYIEELAEKYRIPLYVREGESGIREDWLFAYKKASGDLVTIAHQDDRYEKRYAET
                     LFSMYEKYPDMTVFCSDYATLRMERETEAPKLQLVNAVWLVKKLLRLPLRFKGLSDRK
                     AVKRAALLFGNSVCCPSCTYNKQLIGDRLFESDFEFALDWDNLYQLACRPGRFVCSER
                     PLIFYRVHPGATTKQCIEDNRRKNDETAMFRKMWPESMVKLFMHFYKKAYRAYEK"
     gene            complement(70278..72323)
                     /locus_tag="ACZPCR_00375"
     CDS             complement(70278..72323)
                     /locus_tag="ACZPCR_00375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HIR1229377.1"
                     /translation="MNSKTELKTEPEAEVKADSGTDSKAGFKTASGAGGRRRRLLKAG
                     AWTVFVFFFGLLLELFCNLSLFQNEKEGNFPIPLSEVEYEGFRLDQGERLLLTEDAGT
                     IRIPVGAYVGEVACSYDYDGLLNMTVRAYVENEYGEVRERDAEIFLDKNPKTIQTAWI
                     PVGKETDCVELSVSRGDLYEPGLSYIDFASMPLSFTGFEAVTEAAVNPFRLCFFWCAA
                     GTVIFLIVCRSWIGRHAEAGFLVLALTGGLLLSLSLPANKVGFDEEIHFEQSCWIAHY
                     RDPVQLSPSVFQEFSAGIDTWPLNQPGGLREQRELNRYLDQTGDYRNGSICWSADLNK
                     TTFTGYLGQAALLKAGEIFRLPFSMLFKLGRLGNLLIYALAMALAIRKTPVGKGMLAF
                     IGLMPAPMMLAGVYSYDPTVTAFTALSCAYILEAVLNPERRLSWREFAIIIGAFFWGC
                     RIKAVYAPLILMGFLIPADRFETKKKKNWMRAGFAAMFLLMMASFVLPVLISPSETGD
                     LRGGATSEAGQMAYVLGQPLAYAAVLFKNIFSSFPSYVLGERALGTLGHLGVVSFPWL
                     LYAASAAVILTDTRSSCGKTLTKIQRLWIFLLSGACAVLVWTSMYIAFTPPGNTYIEG
                     VQGRYYLPFLFLVWLAVSPSCVQVKLKNSVYYPLVLALAGTVFYAVYAVDVLSALCL"
     gene            complement(72313..73101)
                     /locus_tag="ACZPCR_00380"
     CDS             complement(72313..73101)
                     /locus_tag="ACZPCR_00380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="HIR1229378.1"
                     /translation="MRALILAAGRGTRISRYLSGKPKCTVDIGNGLCLIWYTVELLKS
                     RGISEIGIVLGYRAQVIRDVLKDCSVKFYVNPFYDVTNSIASAWFAGSFVEEAAQAGE
                     DLMIMNGDVYMEEALLDQILAEKKSPVMFADETRKETADYKFFYENGVLKKYGKELSG
                     DDITGEYIGIGRFSASFLPCFTERMNQMIGEQQHSVWWENVLYEMTRERDVYVQDVGG
                     RFWAEVDYIEDYERILEHRNIERIIPAQLEILRPGNQERSENEF"
     gene            complement(73098..74189)
                     /locus_tag="ACZPCR_00385"
     CDS             complement(73098..74189)
                     /locus_tag="ACZPCR_00385"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008399272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-phosphate-dependent aminotransferase
                     family protein"
                     /protein_id="HIR1229379.1"
                     /translation="MINFAVGPVMMDEEIRSLGAQEIPYFRTPEFSALMKENETLMKR
                     FVRAGDGARALFLTGSGTAAMEAAVLNLFTEKDRVLVVNGGSFGARFEKLCQVLQIPH
                     ETIYLESGKALKKEHLDAYEGKNFTGFLVNVHETSTGVYYDMDLISDFCRRNGLVLLV
                     DAISSFLADDFFMEKWGVDLVLTGSQKALALPPGLSVLVLGERAVERVKEHAVRSIYF
                     DLKDYLKDGERGQTPYTPAVSVLIQLNRRLRRIEEQGLSAELERIRRQAEDFREKIKS
                     LPFEIVSESLSFGETPLHPTGQGADKTPVSAYRIFEILKDEYDIFVCPNGGALADRIF
                     RVGHMGHLTEADNDSLISALKDMQNRGLL"
     gene            complement(74186..75496)
                     /locus_tag="ACZPCR_00390"
     CDS             complement(74186..75496)
                     /locus_tag="ACZPCR_00390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007706548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140327 - flippase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HIR1229380.1"
                     /translation="MKLLRRLLIGSNENIEQRNMIWNMIGSFLYAFASMMLTIAVIQV
                     VGEDQGGDFTFAFTTFGQHMFMVAYFGIRPFHITDTRQRYTFGEYLRLRFITCGAALA
                     FGLLYVAAHGGTYTREKALVVFLMVGYKVIDGFADAYEAEFQRDGRLYLTGKSNTFRT
                     LLSVICFMGSLMATENLVFSCLVAVAAQVLGVLLFNVSVIGCISGVDWRVRKQKTWWL
                     FRDNFLLFLSVIIDFYVFSASKYAVDANMASRDMSVFGAIFMPTSFINLVAGFVIRPY
                     LTKLSASWGKREFSGYLVVVKQLAAIIAGLTVFAVGAAWFLGIPVLSLLYPKLGYALK
                     DCRTALLLIILGGAGNAYVNLFYYSLVIMQKQPFIFIGYTVVGVLAVCLSSPFVRAAG
                     ILGGALSYFILMAALAACFGLTAVFFYRREKKARNMPGEQEGSR"
     gene            complement(75493..76356)
                     /locus_tag="ACZPCR_00395"
     CDS             complement(75493..76356)
                     /locus_tag="ACZPCR_00395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006428601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HIR1229381.1"
                     /translation="MEHLEFYEPETLKRLQGEILSILDDFMAVCDKYHLEYFGIAGTG
                     IGAVRHKGFIPWDDDIDIAMPRHDFDKFIKIIQKTMGDKYLVLNGKNYPGYPLMTTRL
                     VKRGTVFAEKVMKDVDCPFGIFLDLYVLDNVSDNPVLYQIQSWEAWFYSKLLILRSIP
                     EPTLAQKGMKAKLIWSVCRMVHKGLLLLSIKPEGIRFRCEQACRRYRKQQTRRMAFLP
                     DTSPYWNVVDREKCYPLQKLEFEGRMLNFPANLDEMLRSMYGDYMVLPPVEKRKTHYP
                     YRLQFSEETSE"
     gene            complement(76358..77455)
                     /gene="glf"
                     /locus_tag="ACZPCR_00400"
     CDS             complement(76358..77455)
                     /gene="glf"
                     /locus_tag="ACZPCR_00400"
                     /EC_number="5.4.99.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013274405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008767 - UDP-galactopyranose mutase
                     activity [Evidence IEA];
                     GO_process: GO:0009273 - peptidoglycan-based cell wall
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
                     /protein_id="HIR1229382.1"
                     /translation="MKQYDYLLVGSGLYCAVFAFMARKQGKTCLVLEKRDHIGGNIYC
                     EETEGIRVHRYGAHIFHTSDREVWDFVNQFTEFNRYTNSPVANYKGQIYNMPFNMNTF
                     SRMWNISTPEEAREIIERQRSVIQGEPKNLEEQAISLVGTDIYEKLVKGYTEKQWGRD
                     CRDLPGFIIRRLPVRYTYDNNYFNDPYQGIPVDGYNALIERLFEGCEIRTGVDYLEHR
                     QEYENAAERIVYAGTIDGYFGYQFGNLEYRSLRFETETLNTDNYQGVAVVNYTDRETP
                     FTRIIEHKHFEFGTQEKTVITREYPVNWKPGMEPYYPVNDEKNQALYEKYRALAEKEE
                     RVIFGGRLAEYRYYDMDKVIRSALDRAKEEL"
     gene            complement(77675..81091)
                     /locus_tag="ACZPCR_00405"
     CDS             complement(77675..81091)
                     /locus_tag="ACZPCR_00405"
                     /inference="COORDINATES: protein motif:HMM:NF012772.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HIR1229383.1"
                     /translation="MDQRQKRGSDGRRGKAVFLAGSISELAVGQKTDSLTGLWNYDKF
                     LEDMTECLRQSGGYLMVLGIDNFKSINVKNGRTFGNYILKTITETLENLSETPLQLYR
                     LAGDCFAVNFPGKYREDVLDFYDLVKREMEKYCTISAGVAIYSCGDEMDGGQVYQYAE
                     NALDRAKREGKNTLVFFSSDDYQKNLEKIALQDEMRASVRNGCNGFYLCYQPQIDSRD
                     YRLYGAEALLRYESPSRGMVGPGEFIPLLEQSGMICEVGMWVLQTAVSQCREWRKKLP
                     DFHISVNISYVQLRQKGIEEAVLALLQQMDLPGEALTLEVTESMQLQDYSYFNKIFYE
                     WKRYGIQISIDDFGTGYSSLSYLKSIEVDETKIDRCFVSRIQHNAYNYRLLSNMIELA
                     HSARIKVCCEGVETEEELLALKELKPDVLQGFLFAKPYKKEEFERIYICEETKEYQKR
                     EKREAKLRRLDSDTEDRMLENLRQEEIGTIAEGMDEIIYVSDVETYELYYMNAQGRKI
                     TGIYDYKGRKCYEVLQGKENPCEFCTNGKLCKSKFHVWERNNAFLGSRYILKDRLISW
                     QGRKARLEMAINMEEWETLDHQRQAYLMEKGEFGRSGYCRSCLFDSQYAEILDNTNLG
                     LWEIRLDPETEKGEMYADPVMRRIMGITEDITPEECYTHWYSRINAGYYHYINMAVEN
                     CISTGKIIQVEYTWNHPAKGEVTVRCMTVRAADKEGKICLEGYHRIISELERPDFLPD
                     GVKSEMFEYNEKKRTIYFHTDRTMLAGSQVREEDFPESWIRTQMVHPHFAGEFRELFR
                     DVHKKEDPDSREMLFRVKEGEYKWFKVKTRHLSSKAEDLYTIAVLMDLADEERAMELE
                     YMRKTDFYEALLSETVAYAEVDVESEKVMQSGGLWEHYKAENQEQGYTFDEIIRRQID
                     RVVCQEDRDSYQNSINLHYIKEMYKNGIATQEMSFRRMVNGQQCWMKLVFHVFQDRYT
                     ENMYALMYMKNIDAEKRREMAQERADRRDPLTNVYNRKIFESEVREFMTSEKDRKGTL
                     IILDLDDFKKVNDQFGHLTGDELLKSLAEILRSTFRSHDLIGRLGGDEFLVFVKDVTD
                     KEILDRRMTQLFERLRSANSAPLSCSAGISLIEGKIFLFHLKSPKIFPRA"
     gene            complement(80986..81393)
                     /locus_tag="ACZPCR_00410"
     CDS             complement(80986..81393)
                     /locus_tag="ACZPCR_00410"
                     /inference="COORDINATES: protein motif:HMM:NF020036.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HIR1229384.1"
                     /translation="MDVNKELQLYKKTVRFFSESANDYLYVLDLVNRRIHIADKICGK
                     YPLPLPGEEGIPLECWEGIVHHRDRRQLQKEIEEIAQGRKDRHAMNYRLTDRDGHRVW
                     INAKSEVQTDDGGKRSFWREAFLSWRWARRRTA"
     gene            complement(81617..83293)
                     /gene="leuA"
                     /locus_tag="ACZPCR_00415"
     CDS             complement(81617..83293)
                     /gene="leuA"
                     /locus_tag="ACZPCR_00415"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013274411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HIR1229385.1"
                     /translation="MLNYKKYKRVPVVDFPERQWPGRQIEKAPIWCSVDLRDGNQALI
                     EPMVVEEKMEMFRLLVKMGFKEIEIGFPAASQIEFDFLRQLVERRMIPDDVTVQVLTQ
                     CREHLIRRTFEAIQGVKKAIVHIYNSTSTLQRDVVFHKEREEIKEIAVEGVRLVKKYM
                     QAHDGEVILEYSPESFTGTELDFALDICTAVQEEWQPTPEKKMIINLPATVEMTTPNV
                     YADQIEWMNHHFKDRDSIILSIHPHNDRGTGIAATELALLAGAERVEGTLLGNGERTG
                     NVDILNIAYNMFSQGINPELEIENIREIVDVCERCTKMPVDPRHPYAGKLVFTAFSGS
                     HQDAISKGMQALSKRTDGIWEVPYLPIDPSDIGREYEPVVRINSQSGKGGVAFVMDTF
                     YGFKLPKGMHKEFADIIQKIAEAQGEVDPEQIFAEFQKNYIERKEPVHFRKCQITDRE
                     MDEGEFATVADVIYTEHGQEKRFEGVGNGPIDAIQRGLEDTLGVEIRVLDYTEHALRS
                     GSGAQAASYIHLLDVKSGRTTYGVGISSNITRASIRGIFSAVNRLFYTEN"
     gene            complement(83667..84701)
                     /locus_tag="ACZPCR_00420"
     CDS             complement(83667..84701)
                     /locus_tag="ACZPCR_00420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006568766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HIR1229386.1"
                     /translation="MRFRKKETKTKRRTGQTAVLALAAAAALSGMTLTGCSQPGGQKD
                     EEVVIYSNADDEAVEAMKKTLDQNGYEGKYIFQTFGTSELGGKVMAEGTDMEADLITL
                     STFYIDSAQETQQMFQKLNFDFELLNQEEQKDYCAPITSQEGTMIVNTEMIKENHLDM
                     PESLKDLTKPEYKDLISVTDVKSSSTAWLLIQALVDAYGEDGAKETLTGIYENAGPHI
                     ETSGSAPLKKVRAGEVAVGFGLRQQAVADKAKGLPIDFVDPTEGNFSLTESVAVVDKG
                     EKTNPLAQEMAECIIIKGRSELQSYYPNAVYAGETTNPENSSAYPKTFPEPLTVELLK
                     KHEELSESCK"
     gene            complement(84761..86380)
                     /locus_tag="ACZPCR_00425"
     CDS             complement(84761..86380)
                     /locus_tag="ACZPCR_00425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018595330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HIR1229387.1"
                     /translation="MTGRKEYEIKTIYCAVVAVFAFFLAVPVLRLLAESFASEAGAGI
                     ANYISVLTGKGFLTALGHSAAVSIASAVTATAIAFFLAYTIQYTNVPPVFKSLIRTLA
                     TLPMLLPTITYGFAIIYSFGKQGLLTRLFGRQIFEIYGFGGLLFGYVIYTLPVSFLLI
                     LNTMRYIDKKFSVVSRVMGDKPLKTFLQTVARPLLGTLAASMVQCFFLCFTDYGIPAS
                     VGGRYDVVATVLYNEMLGSVPDFNRGAVVAMMMLIPSAVSIALLRWLEKYNIRYSKIS
                     TVEIRKNRLRDGVFFAGSSVFLLGLLSVFAVIFVVPLVSEWPYQTSFTLEHVISTLTD
                     RSLTDVYQNSLFVAVCTAAGGLLVTYGSALATARSGLNSRLKAVIDGIALVTNTIPGM
                     VVGIAFLFIFTGTPLQNTLILIIICNIVHFFSTPYLMMKNSLSKLNSSWEATASLMGD
                     SWFKTIVRIITPNMASTLLEVFGYYFVNAMVTVSAVIFIAGARTMVITTKIKELQYYT
                     KFNEVFVLSLLILFTNLAVKGLLAALKKRMK"
     gene            complement(86382..87200)
                     /locus_tag="ACZPCR_00430"
     CDS             complement(86382..87200)
                     /locus_tag="ACZPCR_00430"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007709616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1229388.1"
                     /translation="MLELKHIKKSYDGVTILSDINLEIQDGEIVSILGPSGCGKTTLL
                     NLILGLTDADEGQILFDGQEMTRLPMEKRGFNIVFQDYALFPNLNVYQNITYGLKNRP
                     GISTKQEVEELIDLLGLREHLAKKIEQLSGGQKQRAALARTMVMKPKILLLDEPLSAL
                     DGVIKESIKEKIRQIARDYHLTTIIVTHDPEEALTLSDKVLIVNQGGISQYGTPEEIV
                     FQPGNQFVKDFILNQLEIKRKNIFRLFNRTVDSLDRSFQEAGAGAEVCVREQAV"
     gene            complement(87438..87653)
                     /locus_tag="ACZPCR_00435"
     CDS             complement(87438..87653)
                     /locus_tag="ACZPCR_00435"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229389.1"
                     /translation="MQYLYVDICESVGRLKSFLRVRDTSEAHREAREKHQAGIPCLAV
                     DDQVILVKNAEHMRELIEEYQLAAENA"
     gene            complement(87655..87861)
                     /locus_tag="ACZPCR_00440"
     CDS             complement(87655..87861)
                     /locus_tag="ACZPCR_00440"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229390.1"
                     /translation="MCNALRELFAEEIEEGKQRGKAEGKIEGKIEGKIEGKCEGERKD
                     EKNYFIWNSLLTGLSAGERGSFPE"
     gene            complement(88258..90852)
                     /gene="clpB"
                     /locus_tag="ACZPCR_00445"
     CDS             complement(88258..90852)
                     /gene="clpB"
                     /locus_tag="ACZPCR_00445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008399253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HIR1229391.1"
                     /translation="MNINKFTQKSLEAVQRTEKLAYEYGNQQIDQEHLLYSLLTIDDS
                     LILKLLTKMGVQENQFLNEVQGAIEKLPKVSGGQVYFSQDANKVLVSAEDEAKSMGDE
                     YVSVEHLFLSMVKQPNRAVKELFKLYNITREGFLQALSTVRGNQRVVSDNPEATYDTL
                     SKYGYDLVERAREQKLDPVIGRDGEIRNVVRILSRKTKNNPVLIGEPGVGKTAVVEGL
                     AQRIVRGDVPEGLKDKKLFALDMGALVAGAKYRGEFEERLKAVLEEVKKSEGQIILFI
                     DELHTIVGAGKTEGSMDAGNMLKPMLARGELHCIGATTLDEYRKYIEKDPALERRFQP
                     VHVDEPTVEDTISILRGLKDRYEVYHGVKITDSALVSAAVLSDRYISDRFLPDKAIDL
                     VDEACAMIKTELDSLPTELDEKARRIMQLEIEEAALKKETDRLSQDRLADLQKELAEL
                     RDEFAAQKAQWENEKASVDKLSKLREEIEHLNGEIQAAQQRYDLNKAAELQYGKLPEL
                     KKQLAEEEERVKNKDLSLVHESVTEEEIARIISKWTGIPVAKLTESERSKTLHMDDIL
                     HRRVIGQDEAVTKVTEAIIRSKAGIKDPSKPIGSFLFLGPTGVGKTELAKALAESLFD
                     DENSMVRIDMSEYMEKHSVSRLIGAPPGYVGYDEGGQLTEAVRRKPYSVVLFDEVEKA
                     HPDVFNVLLQVLDDGRITDSTGKTVDFKNTILIMTSNIGSQYLLEGIDEDGNITEAAD
                     NMAMNDLRAHFRPEFLNRLDEIIMFKPLTKGNIGGIIGLLVEDVNKRLADRELSIALT
                     DSAKQFIVENGYDPVYGARPLKRYLQKHVETLAARLILADGVRAGDVIQIDEQNGKLT
                     ASAVHTEE"
     gene            91221..92576
                     /locus_tag="ACZPCR_00450"
     CDS             91221..92576
                     /locus_tag="ACZPCR_00450"
                     /inference="COORDINATES: protein motif:HMM:NF018513.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HIR1229392.1"
                     /translation="MGIVAFLVYIIFVMIWYLMLKRSIAEAMLLGLVIVCAFNGVDVL
                     PQTFASSLTKALTQDVMAAIILFTVMASIMTQTGIITRLVSILNSILGRFRGGPAYVS
                     ACASAMFGMVSGASSANAATVGSITIPWMTESGWPKEVAATMNTGNAGLGICIPPSSS
                     MFLMLGLPVVAGSVAAGDLYIALMCGGLWSLAYRLLLTRYYVSKYNIPAVPKDRIVSL
                     SSALKEGGTSLTMFLGIIVPLVVITGPVGNFLKTLPAFGEDGVDAMNIIIWVPVLIMF
                     ICIIEGRKLLPKTASGWGKLLSSTAKTCCSCGAVSLFAMAGSNALTATGFGDDLTALL
                     SAMDMPKFLMILIIGFVIALVAGPLNATSTTVSLGPVAYSAMVAVGVSPVTAIVSFLI
                     FASTEGASPPMSSPIFVSSSIAGVEDVSVMFKALIFHYVIPIVLVGALIAMGFLPIIG
                     G"
     gene            92580..92804
                     /locus_tag="ACZPCR_00455"
     CDS             92580..92804
                     /locus_tag="ACZPCR_00455"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229393.1"
                     /translation="MKKLLNYLFIACAALALLLAFGYVAVEMAAVITGNGSLTIWAES
                     HLEAPVCIMCSLTAIVSFIMSYVFRWTSGD"
     gene            complement(92812..93774)
                     /locus_tag="ACZPCR_00460"
     CDS             complement(92812..93774)
                     /locus_tag="ACZPCR_00460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003502746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HIR1229394.1"
                     /translation="MNLKSIEYFLAAAEEMNITRAAERLFISQQALSSHLKRLEDEYG
                     VPLFERRPSLRLTMFGEQMAFYGRQIIQAEANMRGAFSDISKNHRGTLRLGISRLRGK
                     TFFPVIWDFYHASHPNISIELIHGNSNTFEDLLQSGKIDLYIGVDVVENANRKIYELT
                     KEKVQCCFSEELLKTYYPEEWEQILGDFKQGADLKRLLRLPFITVRQGNRLRKGIDAF
                     FSSCRLPQYIFECDEQELIYDMARKGSGAGLLSPVVCWKNYHAQRKTGKPFHVFPVIN
                     EIPENTVSLVYRKDYPLPEYARDFIRDAGMVFQNYSRSIHRHFG"
     gene            93893..94903
                     /locus_tag="ACZPCR_00465"
     CDS             93893..94903
                     /locus_tag="ACZPCR_00465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004462087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta/alpha barrel domain-containing protein"
                     /protein_id="HIR1229395.1"
                     /translation="MDQLTLMDCTLRDGGNVVGKGFPADITDMVLDGLTACHVSIIEL
                     GNSGGIGAYEVAGFTDALTDMEYLEIAKKYMNRGSELGMFLNAKRYREKNVDLAAEHG
                     LSFLRVGADAGDGDIALTAIADMKKRNLKAFYSAMKAYLLTPAELAEEAKKLEAAGLD
                     EYTIMDSAGTMLPDQAAAYTEALADALSIPVAFHCHNNLGLSAANALAAAQNGAKILD
                     CGLMGMARSAGNLPTEVCVAMMQRHGQMMDVDLFGMLDFIENRLQPAMETHNYHNPIT
                     PTDLTLGFSGCHSSFLKLFRQTATEKKVNLFRLITEVSAVNQKNPSAQLIEETADRLL
                     SE"
     gene            94936..95904
                     /locus_tag="ACZPCR_00470"
     CDS             94936..95904
                     /locus_tag="ACZPCR_00470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003509616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HIR1229396.1"
                     /translation="MKKVILAGTYPAHTFEKLRAMLPEEEFELKAVDTPEAYDAMTDA
                     EFMILRIFKAPRPVIERNPNLKMILRWGAGFDSVDIQAAGEHGVCVTNTPGANAGAVS
                     ELAVLLMLAVGRKLLCHTESLAKGEWSKNTFLNGSFCLNGKTLGVIGAGNIGRQVARK
                     AQAFGAVTNYYDPFRLSPEMEAEYHLSYLPLKELLASSDLITLHVPLTEENRHMIGAE
                     EIASMKDHAILINTSRGGLVDDKALAEAVASGKLLGAGLDVVEEEPLPAGHPLLTNPN
                     IVVTPHIGGGTADIGDVIMPMLAEDIKTMAAGNLPIHTVNKEYLNK"
     gene            complement(95969..96502)
                     /locus_tag="ACZPCR_00475"
     CDS             complement(95969..96502)
                     /locus_tag="ACZPCR_00475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005610382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036094 - small molecule binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3H domain-containing protein"
                     /protein_id="HIR1229397.1"
                     /translation="MTGTDRRNEIVKIIQKSPSPVPARSLAASCKVSRQVIVQDIALL
                     RAAGYDIISTNRGYILNSLSQVERVFKVRHTNEQMEEELNAIVDMGGCVKDVAVNHRI
                     YGRMEAELNISSRRKIALFLEDIKHGSSSPLSSITSGYHYHTVSADSRETLDAIEEML
                     RQRGFLVEERKEDSRHK"
     gene            complement(96552..97421)
                     /gene="nadC"
                     /locus_tag="ACZPCR_00480"
     CDS             complement(96552..97421)
                     /gene="nadC"
                     /locus_tag="ACZPCR_00480"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD+ biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HIR1229398.1"
                     /translation="MFNSITMKLQADHLIMEALKEDISSEDVSTNSVMKQAVKGTVDL
                     LCKEDGIIAGLDVFKRVFELLDPATECEFFCADGDEVKAGQLMGKLTGDIRVLLSGER
                     VALNYLQRMSGIATYTHSVAELLKGSKVKLLDTRKTTPNMRIFEKYAVRAGGGHNHRY
                     NLSDGVMLKDNHIGAAGGVANAVRMAKEYAPFVRRIEVEVENLDMVKEAVEAGADIIM
                     LDNMSPEDMKKAVQLIDGRAETECSGNVTKENIARYIDCGVDYISSGALTHSAPILDI
                     SLKHLHPVEQPTV"
     gene            complement(97469..98638)
                     /locus_tag="ACZPCR_00485"
     CDS             complement(97469..98638)
                     /locus_tag="ACZPCR_00485"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009249419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008734 - L-aspartate oxidase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD+ biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HIR1229399.1"
                     /translation="MKTETDIVIVGTGVSGLFAALNLPRDRRITMITKSDAESSDSFL
                     AQGGICVLRDDEDYDSYFEDTMRAGHYENRKESVDIMIRSSREIIEDLIGFGVEFEKQ
                     DGELAYTREGAHSRPRILYHEDITGKEITSKLLAAVRKCPNVEIREFTEMTDIIEENG
                     RCAGITARCGDELLEIRAEFTVFASGGIGGRYKHSTNYPHLTGDALTVAEKHGIRLEH
                     LDYVQIHPTTLYSEKPGRRFLISESVRGEGALLYNKKGERFVDELLPRDVVTNAIRKQ
                     MEADGTDHVWLSLEPIPKETILSHFPNICQRCLEEGYDVTKEWIPVVPAQHYFMGGIW
                     VDSESRTTMDRLYAVGETSCNGVHGANRLASNSLLESLVFAKRAAGDMKRKLGEQ"
     gene            complement(98718..99629)
                     /gene="nadA"
                     /locus_tag="ACZPCR_00490"
     CDS             complement(98718..99629)
                     /gene="nadA"
                     /locus_tag="ACZPCR_00490"
                     /EC_number="2.5.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005610388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008987 - quinolinate synthetase A
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD+ biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HIR1229400.1"
                     /translation="MTRNIAEEIKRLKEEKNAVLLAHYYVRPEVQEIADYIGDSFYLS
                     KLAVGLEAQTIVMCGVSFMGESVKILNPEKTVLLPDASADCAMAHMASVETIEQMRKT
                     WDDLAVVCYINSTAELKRHSDVCVTSANAVKIVKALPNKNIFFIPDRNLARFVAEQAP
                     EKHFVFNEGFCPVHEELKLKELQALKEQHPEAEVLTHPECGEAVCRESDYIGSTSGII
                     AHAEASGAKEFIICTENGVRFELGKRCPGKKFYFTATEPVCGDMKLITLEKILRVLET
                     GENEVLADPSMVEEAGKPLEEMLRLAK"
     gene            complement(99760..101355)
                     /locus_tag="ACZPCR_00495"
     CDS             complement(99760..101355)
                     /locus_tag="ACZPCR_00495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006859914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HIR1229401.1"
                     /translation="MAQIQAKNLSFRYDGGEDVFTDMSFSIGTDWKLGLVGRNGKGKT
                     TLLRLFMGEYEYEGRILSSEPFEYFPYHVPDPDKNTIDVLDEVCPDGEFWMLLREMNL
                     LELREETLFRPFSSLSRGEQTKALLAALFCREGRFLLIDEPTNHLDAEGRRLVSRYLN
                     RKKGFILVSHDRSFLDGCIDHVMALNRESVEIVQGNFSAWRENRDRRDAFERQENEKL
                     KKEIGRLQASAAAACAWADRSEGMKIGTGSFVGGKFIGTRSYLGEKSRKMQQRRKNLE
                     QRQERAIQEKEKLLRDVEEEQPLKILPLTHWKKELIRVRDLRLSYQPGEEAGSGLSAR
                     KKGQGLSFVLEQGQRIALTGGNGSGKSSVIREILKTAAQETQEAFKEAQADGPERGAC
                     GLIRLSGELSLPSDLKISYVPQDASFLKGDLTAFAREQEVDRSLFLTVLRKLDIPREL
                     FHKPMEQYSEGQKKKVLLAKSLCQQAHVYVWDEPLNYIDVFSRMQIEEVIRSNRLTML
                     LVEHDQAFLKAVEAEEVPAGIAL"
     gene            complement(101412..101630)
                     /locus_tag="ACZPCR_00500"
     CDS             complement(101412..101630)
                     /locus_tag="ACZPCR_00500"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229402.1"
                     /translation="MAEQKYGILFVDSISYEAGKPLFPAPVLRLQAGLKPENKSRRAD
                     AGGIDLRYQYSWKGCRRFSASFFCFTGR"
     gene            complement(101821..102453)
                     /locus_tag="ACZPCR_00505"
     CDS             complement(101821..102453)
                     /locus_tag="ACZPCR_00505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015544253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229403.1"
                     /translation="MKKTGKMAAAVLLAASVAALASGCGQKEAQEISAPESTVSQTEE
                     SASQAEETESLEEENQSGAVSVMTGTVLDAAMNSIVIQNEEYPQGLIFSKENSASSFS
                     EGLTLDMNVTLFYTGETDGEDTTKTEVILVRESRDSDSTLTAGSVSGTVSEVTSEAVV
                     IETEDGEKISVARGHELSETEKEPEAGDQLTVYYSCPGGDESVKEAELIR"
     gene            complement(102484..103986)
                     /gene="malQ"
                     /locus_tag="ACZPCR_00510"
     CDS             complement(102484..103986)
                     /gene="malQ"
                     /locus_tag="ACZPCR_00510"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HIR1229404.1"
                     /translation="MAKTMLKRGAGILMPVSSLPSPYGIGTFGACAYEFADKLVKARQ
                     SYWQVLPLGPTSYGDSPYQSFSAFAGNPYFIDLDVLKEEGLLTKEEIESCYWCDREDE
                     VKYDAVCYYRFPLLKKAFERSRFRETKEYETFCQENSGWLEDYALYMALKGHFNQEEW
                     LNWEEPIRRREPEAVAAYKAELSEEMDYWKFLQFKFYGQWDKLRAYVNEKGIQIIGDI
                     PIYVALDSADVWVHPELFQLDPETLKPLKVAGVPPDAFSETGQLWGNPLYDWNSLEKT
                     DFAWWRDRMKAAARLYDVVRIDHFIGVVQYYSIPYGAEDGRTGEWRKGPGEKLTKAVN
                     EAAGKTKIIAEDLGVFCPEVKELLQKTGYPGMKIIEFAFSGDRFNEHLPHCYEPNSVV
                     YGGTHDNETLIGYFKPEKRQWWELQYIADYLGAAHREEVPDRVFRAAYGSVASVAIFQ
                     MQDVLKLDNDARMNTPGTVGGNWKWRMKPGAFGDSETGYLAFLVDTFGRF"
     gene            complement(104116..104841)
                     /locus_tag="ACZPCR_00515"
     CDS             complement(104116..104841)
                     /locus_tag="ACZPCR_00515"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HIR1229405.1"
                     /translation="MRENGNLRYTTLLFDVDNTLLNFDASEEEAFKSLLLHFGMEPKD
                     SLLQEYHQINRSCWELFEEGKMEKEEVLLRRFEIFFSRHNCQADGKEAEAFYRERLGD
                     SAILIPGALELCRDLSRKYDLYVVTNGVADTQYRRLKSSGLDPYFKGIFVSEEAKSPK
                     PQKEFFEYCFEQMRLLGVERPKERRREMLLIGDSLTSDMRGGENAGVDTCWYNPKKLS
                     NDKDVSVTMEVSSYEEIREILLF"
     gene            complement(104841..106127)
                     /locus_tag="ACZPCR_00520"
     CDS             complement(104841..106127)
                     /locus_tag="ACZPCR_00520"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HIR1229406.1"
                     /translation="MIIKNGRVIDPKSGFDGIADIIIKDGKIKKILKKAEASEVQEAL
                     PETGEEVIDASGLIVAPGLIDVHVHFRDPGLTYKEDIETGAAAAKAGGFTTVVMMGNT
                     KPVIDNEETLRYVLEKGEQTGIHVLSAANITKGMKGKELTDMEALRAQGAAGFTDDGV
                     PIMDVKLLMKAMETAKKLDVPLSFHEEDPGFIINNGINRGAVSEALGIDGSPRVAEDS
                     LVARDCMIALYTGACVNVQHISSKNAVAAVALAKKLGADVWAEVTPHHLTLDETAVLE
                     FGSLAKMNPPLRTKEDREALIAALKDGTIDMIATDHAPHSKEEKEKPLTEAPSGIIGL
                     ETSLPLCVTELVKKGHLSYVELFEKMCLNPARLYRLDSGYLAEGGPADLVIFDDQEEF
                     AAGPFESKSSNSPFTGRKMFGKVKTTICSGKAVYQG"
     gene            complement(106145..106522)
                     /locus_tag="ACZPCR_00525"
     CDS             complement(106145..106522)
                     /locus_tag="ACZPCR_00525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009242305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HIR1229407.1"
                     /translation="MTFTFAHNNFNVIDLEKSLKFYEEALGLKEVRRKEAADGSFILV
                     YLGDGETPHQLELTWLRDWEKDSYNLGDNEFHLAFEVDDMEAAHKKHEEMGCICYENP
                     SMGIYFIADPDNYWLEVVPKKMK"
     gene            complement(106519..107223)
                     /locus_tag="ACZPCR_00530"
     CDS             complement(106519..107223)
                     /locus_tag="ACZPCR_00530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HIR1229408.1"
                     /translation="MKVIYIHHSAVSVETEHSILLFDYFKGELPDFDPGKPLFVFASH
                     FHEDHYSPVIFERFREREGVSYILSDDIKGRRIPKEALPLIHFVKPGQTLELGEVKIQ
                     TYKSTDEGCAFWVSLEGLELYHAGDLNNWWWEGEDKAWNHNMAANYRREVEKIAADHP
                     EGADAAFIPLDPRQEQWFYLGMDDFLKKVEAKAVFPIHFWGDFGVSGRMKALPCSGPY
                     RDRIMEIQREGEEFEL"
     gene            complement(107266..107667)
                     /locus_tag="ACZPCR_00535"
     CDS             complement(107266..107667)
                     /locus_tag="ACZPCR_00535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008399202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HIR1229409.1"
                     /translation="MLEAGIKGREEVMVTEANSAAAMGSGLLPVFATPAMVALMEQTS
                     WKSVAPYLNEGEGTVGTSLNISHSAATPLGMKVWCESELTEVDRRRLVFHVTCYDEAG
                     VIGEGTHERFIIGNEKFLAKAEQKKNASKGE"
     gene            complement(107716..108093)
                     /locus_tag="ACZPCR_00540"
     CDS             complement(107716..108093)
                     /locus_tag="ACZPCR_00540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HIR1229410.1"
                     /translation="MIFIGGISSAVKQLEYLKTVICSVCGGYGRYQVFMTYTYFSFFF
                     IPLFKWNRKFYVKMTCCGSVYELNRETGMKILRGQAADIGESDLSLVQRGAGNLAGEG
                     SCPDCGCRLSEDFSYCPQCGRKL"
     gene            108271..108891
                     /locus_tag="ACZPCR_00545"
     CDS             108271..108891
                     /locus_tag="ACZPCR_00545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002575249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HIR1229411.1"
                     /translation="MKREEKNQQMRRRIMDSALAEFSGQSYGASSVNNICSAQGISKG
                     IIYHYFKTKDELFLACVKECFSLLTAYISERMQQGEGTARERLEQYFTCRMAFFASHP
                     IYQRLFCEAIVSPPEHLSAEIQNCRREFDALNIGILEQILAQLPLRKDHTKEEIIEIF
                     RQFQDFINARYSAADLQGSEFELHENQCRKALHILLFGIIDHSVSE"
     gene            109133..110083
                     /locus_tag="ACZPCR_00550"
     CDS             109133..110083
                     /locus_tag="ACZPCR_00550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007714577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA glycosylase"
                     /protein_id="HIR1229412.1"
                     /translation="MIKPILKSFTCMDLRQIADSGQCFRMTELSDMPGRFSVISQEHY
                     LEIAQLECDWKQTDETRFEAKTFAFYCKKEELSFWERYFDLDQDYEAYINSVRKRDSY
                     LQHAAQAGSGIRILNQDPWEMILTFVISQQKTIPKIREAVEALSRQFGTEHRSAVLRG
                     SQEKEITWHSFPTPSQLAEVSEETLRALKLGYRAKYIVRLCQDAAGGRLNLDAFKTMG
                     YEEAMAYLKSFYGIGEKVANCICLFGLHHIEAFPVDTWIEQILMQEYYRKKKKKYDAL
                     PKSRLYSEIIHDYFGIYQGYAGVMQQYIFYYERVQRGKVR"
     gene            complement(110210..110644)
                     /locus_tag="ACZPCR_00555"
     CDS             complement(110210..110644)
                     /locus_tag="ACZPCR_00555"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229413.1"
                     /translation="MKHKKTAAQLLLVIAAILSMTMTAFAGPQKRVDPRWSYFTTVVG
                     DLDISSSGKATAMATVSANRNKVDSVKVTCNLQRLEGSTWKTIKSWSEESEAGAPHIV
                     MMEKTYYVVEGYSYRIQVHSKAYMDGALKESITSTFDYGYFH"
     gene            complement(110708..111469)
                     /locus_tag="ACZPCR_00560"
     CDS             complement(110708..111469)
                     /locus_tag="ACZPCR_00560"
                     /inference="COORDINATES: protein motif:HMM:NF025643.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4367 domain-containing protein"
                     /protein_id="HIR1229414.1"
                     /translation="MKTREKRDKMLLTLALLEQLEQDEELKEFESCERRENRKGNKGA
                     QSGAAHVFSRQHEERMEQLFKMAALQEKKKKRRRRMRKAAAGLAACLAVSVYMGFTSS
                     AFRTPVLNFFTEVRETYSELLVEKDDRKGVTEHFQEYEPEYTVKGFYVSLVKEKEGEF
                     VISYVAEEGQWYDFYYYKEPYNSQVDTEDLVETEVEINGRQGMLYQKEDYSQTVVRST
                     AGQFGVVGNISALEEEKVLESVKIQAIELKNKNFY"
     gene            complement(111466..112002)
                     /locus_tag="ACZPCR_00565"
     CDS             complement(111466..112002)
                     /locus_tag="ACZPCR_00565"
                     /inference="COORDINATES: protein motif:HMM:NF019265.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1229415.1"
                     /translation="MLKEPGELSKFQALYALYSGSMYAAAYKILNQAEDAEDAVQLSL
                     IKVIRNLDRVTAEEMSDIRTKNFLMTITRNTAIDMYRKRQKQPISSEEIEMEIAPFAP
                     STEEIFFDRVSVTDLAAAISQLDQKYKDVLRLYYINELSSKEIGELLNLSQFTVNSRL
                     QRARGKLGKIIKEREEGV"
     gene            complement(112220..113092)
                     /locus_tag="ACZPCR_00570"
     CDS             complement(112220..113092)
                     /locus_tag="ACZPCR_00570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HIR1229416.1"
                     /translation="MRYEGIVYRPPSEARSLIVQVTIGCAHNTCTFCNMYKAKDFRVR
                     SMEEIMEDLKEAHNSYGAYVQKVFLADGDALVLQTEKLLEILKAVRELFPNCTRVASY
                     GTAQDILRKSEEELKSLQKAGLGIVYVGAESGDDEILASICKGVTAEELKAAGQKLKR
                     CGIQTSVTLISGLGGRSKVEEHARSCAELISAMNPEYASFLTLRLYEGTPMYDDVVTG
                     RFERITADEIVDEMKIFLEHVDSPGTVFRTNHASNYVVLAGNLNEDIPSMLAQLDEAK
                     KTHHYRRFRETGDL"
     gene            complement(113089..114768)
                     /locus_tag="ACZPCR_00575"
     CDS             complement(113089..114768)
                     /locus_tag="ACZPCR_00575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008399188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HIR1229417.1"
                     /translation="MKENHGRGGSMKPEKDRQQAVKLLLYLAEIAVLTAAVFLVVRFL
                     PGGGRPWNRLPESGTLAETLPELSKPQEESGAADASRPENETESGAEKEENGEADSVP
                     AFSQNGSGQKEGEEPEEPPYEPPYFIIASDLHYQSPLMTDFGEAFQNFVRNDDGKVVE
                     YVDSITDAFLAETAEKQPDALILSGDLTQNGEKVNHEELAKKLRLLESQGVPVVVIPG
                     NHDINHPSAASFEGTEKKKADNINAEEFYSIYREFGYDEAMDRDEKSLSYIYQADERY
                     WLMMLDSCQYDPENKIGGRIRKETLLWMEKWLERAREEQVMVIPVAHHNLLKESTLYP
                     EDCTLENAVQVIDLLEQYGLPVYISGHLHLQRVKKHGNGGPSQAEESYGIYEIVSDSM
                     VIPPCQYGELRWQEDGSVQYETCPVDVAGWAASQGITDENLLNFPQYSGDFLIETVQN
                     QVYGALSAIPDDRKFHMAKLYGQINSAYCAGTAVNRRDVKENQMYFYWNRYLGTSEWY
                     ENLQAMIKDTGKDHNSLILQAGEDFPDWYKQEEIETAEKPADHTEKGEELR"
     gene            complement(114781..116280)
                     /locus_tag="ACZPCR_00580"
     CDS             complement(114781..116280)
                     /locus_tag="ACZPCR_00580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1229418.1"
                     /translation="MNIKRAKQEIKDCIEAYLLKDERGEYVIPPVRQRPLFLIGPPGI
                     GKTQIMEQVARECRVGLVSYTITHHTRQSAIGLPVIEKKNYGGREYQATEYTMSEIVA
                     SVYDKIQETGIPEGILFIDEINCVSETLAPAMLQFLQCKTFGNHQIPEGFIIVAAGNP
                     PEYNKSVREFDIATLDRIRRIQVEADFEVWKGYAVNAAVHPAVISYLEARKEHFYRIE
                     STVSGKQFATPRGWEDLARLIEVYEKLGKTVDREVTAQYIENPRIAKDFAAYLELYYK
                     YQSEYQIGAILSGTVSESVISRASRAAFDERFSVVNLILSHLNGEFREAGKREEMISL
                     LFGRLKEIRDERDLSLLERLARELDEEAEKQRKAGLIDREQEYLMRSAAERLEKYAGI
                     LKKEGGTEFEPGFERVRELFLKDREAYESFCDETLQKLERGFDFLEAAFGDSQEMVLF
                     VTGLTASRSGVGFLREHECERYYEYNRRLLFEDQESGILERLNRLEERG"
     gene            complement(116280..117605)
                     /locus_tag="ACZPCR_00585"
     CDS             complement(116280..117605)
                     /locus_tag="ACZPCR_00585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vWA domain-containing protein"
                     /protein_id="HIR1229419.1"
                     /translation="MEKSPIFLEQEKAQELCDICGEILRNARNELYLNLRFMDTALSA
                     LLFSPDTQRRGVATDGFCLRFQPEDLVLLYRRGRVYVNRIYLHMVLHCIFLHMDTRRG
                     REKNLWDLSCDIAAEALIDGFLIKALRLPPSPARREMYERLKKQTAVMNAQSIYDALE
                     KEAFSEGRLKRIAAEFYADSHDLWEDDRKPNRSRERQNRWEEIRQTMETEMETFSKMP
                     SGEAGDLRTQIHIENREKTDYREFLRQFSVMRETMQVDMDAFDYIYYDYGLRTYGNMP
                     LIEPLETKEIKKIQEFVIVIDTSMSCSGDLVKKFLSQTYQVLSESESFFTQVNVRILQ
                     CDEKVQSDRKIENQKDLARYMDQMEILGQGGTDFRPAFEYVNQLILEGEFTNLKGLIY
                     FTDGYGPFPVKMLPYETAFVFMREDYSDADVPPWAIKLILGPEELEGES"
     gene            complement(117609..118625)
                     /locus_tag="ACZPCR_00590"
     CDS             complement(117609..118625)
                     /locus_tag="ACZPCR_00590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HIR1229420.1"
                     /translation="MFDGKEYVYAVYEEKSFSKAAQKLYITQPALSTAIKKVEKKIGS
                     PIFDRSTSPIGLTPSGEVYIDAIEKLFALEQNTINQLNNLNGLLAGKLTIGGTVFLTS
                     YILPSLLAEFSRRYPQIKIELVEGTTSQLTDKLFSEEIDLLIDNSEMDDKNYDKYYYS
                     TERIVLAVPSGFEINQELNQYRLSRESIESGAYQSREFPELPLPLLKKTPFIFLKEEN
                     SIYKRGVKMCSRQNYTPNIILKPDQVITAFNMASKGMGATFIPDALVSSVPFDVPLCY
                     YKMDDGLAIRNVYFYKKRNKYMTKAMEEFLKVSLGKNGAMPVPVPAAERPSGKDHAGR
                     TKEA"
     gene            complement(118748..119818)
                     /locus_tag="ACZPCR_00595"
     CDS             complement(118748..119818)
                     /locus_tag="ACZPCR_00595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat protein"
                     /protein_id="HIR1229421.1"
                     /translation="MGLELLYEKKEDSVKILRCFGETDEIWLPDQIEGLPVAELGDYI
                     FSEGMRTEPKGLLWRENGEDEEISAPPVCGPSLRSVRLPAFLKRLGRYAFYNCDGLKR
                     LAFPSAIRDIGAGAFNGCRKIEELTVEADPREKSCLKEILSELNETVAVHYRERGEIG
                     KKTLLAELLFPAFYEEAVENTPARITETHVHGCGHRYRYCFENTQLLFREYDSLFPYM
                     KAQENVPEAVKLAADRLRFPLRLSREAESAYKFYLLDHLDETGEYIASLSDAAEWDWL
                     VNQCFGIKRVEHAAAVWLGNEGLAGRAHEEYSNIKEPVLGKTGFDKLVETAGRLNQTE
                     AVGILMEAGRRAFPPKRRTFEL"
     gene            complement(119861..120547)
                     /locus_tag="ACZPCR_00600"
     CDS             complement(119861..120547)
                     /locus_tag="ACZPCR_00600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008399178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HIR1229422.1"
                     /translation="MTGTIVNVGAIVAASLIGSRVKKGIKEEYQGAMFNAMGLAALML
                     GVHSAAGGMSDSRYPVLFIASLALGSLAGTLLDLDGRFQRMMASFHASQLGEGLSTAI
                     LLCCVGTMSILGPIESAIYGNNTYLYTNATLDFVTFIALSSTYGIGIALAAAVLFCWQ
                     GSIYLGASALSGFLSEPLMAEISIVGGVLIAASGLSILKIKDCKTMNMLPSLLVPPVW
                     FLIVKALGLG"
     gene            complement(120544..121026)
                     /locus_tag="ACZPCR_00605"
     CDS             complement(120544..121026)
                     /locus_tag="ACZPCR_00605"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003505953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HIR1229423.1"
                     /translation="MREKSQLTTLCYIEQDEKYLMLHRVKKEKDVNKDKWIGIGGHFE
                     EGESPEECLLREAEEETGLTLTSWRFRGLVTFLAEGWPTEYMCLFTADGFEGTIKECS
                     EGTLEWVDKTRLDQLNLWEGDKIFFRLLEENRPFFSLKLEYSGDRLIRWSLDGEEGKA
                     "
     gene            complement(121078..122544)
                     /locus_tag="ACZPCR_00610"
     CDS             complement(121078..122544)
                     /locus_tag="ACZPCR_00610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HIR1229424.1"
                     /translation="MRKRKAAAFAIAAGLCLTVSGCQKTAQTGQEAQTSEAQTKPSES
                     QNAGRETEESKEEAPETGESLEETTEEETQAETGEEPLYEIVLATDIHYLAEDLAGNR
                     CQSFINYVYGGDGRVLLYSWEILDAFIEDMKEKDPDLLLLSGDLTLNGEKASHEELAV
                     LLEELDEEGITTLVIPGNHDINNPNAKKFSGTNSYPVDSITAEEFEDIYAEFGYVAAD
                     SRDPNSLSYLYKVDSSLWLLMLDSCQYDPVNQVGGMIQSGTYKWMEPILYEAWENDTE
                     VITVSHHNLLEQSGVSDAFYDDCTIEHSEELLQMLSDNEVRLHLSGHLHLQHYMEEDD
                     VAEVVTGSLVMAPCRYGVMDLYEDGSITYHTETVNVEKWARENSYKNPDLADFFHYSE
                     NFLHQISYEHAVSDLERQNRKGTLHLSGDEIETMSQFYAKLCVYYYGGKMYEIADEVK
                     DDPAARLWDKYQYASELSDFLRRILEDEAKDFGKLYLD"
     gene            complement(122587..123738)
                     /locus_tag="ACZPCR_00615"
     CDS             complement(122587..123738)
                     /locus_tag="ACZPCR_00615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015559427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HIR1229425.1"
                     /translation="MITLLERIFIKQGKDERRAYGILCGTLGIALNLLLFAGKYLAGF
                     LSGSIAVMADAFNNLSDAGSSVITLLGFQFAGQAADEEHPFGHGRIEYLSGLAVSIAI
                     IVMGVELGRSSIEKIIHPEAVDTGVLSMAILLASVAVKLYMSFYNRRIGAKIDSAAMK
                     ATAMDSLSDALATSMVLISMLIMKFTGVNVDGWCGVLVAVFILKAGYEAAKETLNPLL
                     GQAPEPEFIEEIQNIVLSRPEIIGIHDLVVHDYGPGHRMVSLHGEVDGSQDIFELHDA
                     IDGVEMELQERLGCQAVIHMDPVNLKDPEMKEKKAMVEQIVKAVDSRLTIHDFRLVHG
                     GGVTKLLFDVVMPFEMKMGEEELKKQVQDQVCETMPCCCAIIQIDHSYV"
     gene            complement(123735..124493)
                     /gene="yaaA"
                     /locus_tag="ACZPCR_00620"
     CDS             complement(123735..124493)
                     /gene="yaaA"
                     /locus_tag="ACZPCR_00620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HIR1229426.1"
                     /translation="MKLIVSPAKRMQVKCDDMPWRAAPVFQKEAGELLRTLQGFSEAE
                     LKALFKANDAITHENYLRYQTMRLDQGLTPAVLAYVGIQYQYMAPQIFTKEQWEYVCS
                     HLRILSGFYGVLRADDGVVPYRLEMQARLKIGLHKDLYGWWGDKIYRELSEGRPAVIL
                     NLASKEYSRAVEPYLASGDRFVTCVFGTLSEGKVKVKATEAKMARGEMVRFLAERGAE
                     TPEEAKAFDRMGFSFCPERSSDCEYVFLKEAETK"
     gene            complement(124560..124982)
                     /locus_tag="ACZPCR_00625"
                     /pseudo
     CDS             complement(124560..124982)
                     /locus_tag="ACZPCR_00625"
                     /inference="COORDINATES: protein motif:HMM:NF013691.6"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
     gene            complement(124995..126851)
                     /locus_tag="ACZPCR_00630"
     CDS             complement(124995..126851)
                     /locus_tag="ACZPCR_00630"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007863744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease"
                     /protein_id="HIR1229427.1"
                     /translation="MRFTRIRIKNFKSIRDMELSDIDSALILVGKNNTGKTSVLDAVR
                     LMTGGREVLDGDFDESGQNIEIETELKIEEEDLLLFHSQAVVSAYRRFEIWKRDFEKK
                     LPSFQNGILSFTFLVNREGRKRFFDGFRKHNPYIAQVIPKLHYIDTERELNAFQSDLF
                     LLGDSRLMNQMRNGACLFDSGRACSHCFQCIGLINQKKPEELNALEAQKLFEYKLYQL
                     NLGRVAERINENFEKNGGFDEIRYRLQGNLTELFSVQAELYSKERGTVSPVSQMSRGM
                     RCIYMLSLLETYVEEESQLPSIIVVEYPELFLHPRLQKTASEILYRLSKKNQVIFSTH
                     SPQLLLNFTSRQIRQVVLDEEFSSVVRSQVDIGEILDDLGYGAGDAMNVDFVFIVEGR
                     QDKSRLPLLLKKYYSEVYKEDGSLSRVSIITTNSCTNIKTYANLKYMNQVHFKDQFLM
                     IRDGDGKDRGELKRQLCRYYEEQGKRDVDHLPRVTEKNVLILRYYSFENYFLNPEIMT
                     KLSVVPSEEVFYDILYEKWREYLCRLTSGKKFKAALGRDLKSPEDLKEHMDLFKIHLR
                     GHNLFDIFYGRYKKQETELLSRYIDLAPREDFADILDSIDQFLYFDSRKKKN"
     gene            complement(126973..128529)
                     /locus_tag="ACZPCR_00635"
     CDS             complement(126973..128529)
                     /locus_tag="ACZPCR_00635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002589397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 and LysM peptidoglycan-binding
                     domain-containing protein"
                     /protein_id="HIR1229428.1"
                     /translation="MELMKNNIHMNRQKGTAVSQITLDDDFIVPDTMDDVSAVLLGNG
                     DIQIESSRAQGDRVLIRGKLSFAVLYRRESGGLQSLKGEIPFEETVNVPELEEKDSFQ
                     VSWNLEDLNTGMINSRKLNIKAVVMLEVRVESLYDAEAAVDVKTDDGRVEIQRRDIDV
                     AAIAVRRKDTYRIREELSLSANKPNMETILWREMKLRGVSCSPVQGAVHLEGELLIFV
                     IYSGEGEHTPVQWVEESIPFSGEVELSEAEESMIPFVPVRLLHQEIEMKPDSDGEMRV
                     LLADAVLELDMKLYEEQHVELLSDMYSTGCELVLDTGTACFDRLLTKNICKCKTAEKL
                     NLRQPERILQICHSTGEVKLDAAEPKEDGLHLEGVLEVGLLYLTDDDAAPVGYAEEMV
                     PFRCTAEASGMDENSVYQLNMGLEQLTAVMLGSESVEVKAVITADLLALQPVCEQVIT
                     GARTEPLDLKKLQEMPGIVGYIVQPGDSLWKIAKKFHTTVDHVMEANGLERGEARPGE
                     RLVLVKEISQ"
     gene            complement(128728..129225)
                     /locus_tag="ACZPCR_00640"
     CDS             complement(128728..129225)
                     /locus_tag="ACZPCR_00640"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229429.1"
                     /translation="MKQWSMILMIAGLICIAEGLVRLKKPDLRFFQIRQTEELEPEQR
                     REYIRKGAVSSICLGAVCLLGAGLYGRIGDMKVLILLLGGILLFLIYSLWLNKKYLGN
                     FTLLSGAGKKERMLYILVVVVLYAVIYWGFYQYAGLLNHSLAMFLITAGILLAAQMIL
                     FRKKK"
     gene            complement(129260..130132)
                     /locus_tag="ACZPCR_00645"
     CDS             complement(129260..130132)
                     /locus_tag="ACZPCR_00645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002601844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine biosynthesis TtcA family
                     protein"
                     /protein_id="HIR1229430.1"
                     /translation="MVKLQDNETVRDNQKKPADRCRDIEKSVIKQFRKEIWRPFVKAL
                     NEYDMIQEGDNIAVCISGGKDSMLLAKCMQEILRHGKMEFGLHFLVMDPGYNPENRKM
                     IEENAKIMGIPITVFESDIFNVVVDVDQSPCYLCARMRRGHLYANAKRLGCNKIALGH
                     HFDDVIETILMSMLYGAQVNTMMPKLHSTNFEGMELIRPLYLVKEADIEAWRDFNNLR
                     FLQCACRFTEAISREEEAHMSKRQEMKELIAKFRTINPHIETNIFKSVENVNLDACIG
                     YVKGKERHHFLEEY"
     gene            complement(130113..130808)
                     /gene="cysE"
                     /locus_tag="ACZPCR_00650"
     CDS             complement(130113..130808)
                     /gene="cysE"
                     /locus_tag="ACZPCR_00650"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HIR1229431.1"
                     /translation="MILKDIWLDVKAVKERDPAARSALEVLLLYQGVHALIWHRIAHW
                     FYQKRMFFIARLISQIARFFTLIEIHPGAQLGHGILIDHGAGVVIGETAVVGDNCTIY
                     QGVTLGGVGTKKGKRHPTLGNNVTVGSGAKILGSFQVGDNCSIAANAVLLQPLEENIT
                     AVGIPARPVKKDGVKIQKKEKVVLGEHDRKLVEQIEALKGENKQLKRELRRMERELDE
                     KDKGEKKDGKIAG"
     gene            complement(130924..131295)
                     /locus_tag="ACZPCR_00655"
     CDS             complement(130924..131295)
                     /locus_tag="ACZPCR_00655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012741985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HIR1229432.1"
                     /translation="MSKTLKEYLAMAYRMEVVEDKEEGGFVVSYPDLPGCITCGETVE
                     SAVANALDAKKAWLEAALEDGVAIQEPDSLEDYSGQFKLRIPRSLHRLLAEHSQREGI
                     SMNQYCVYLLSRNDAIFSRQG"
     gene            complement(131288..131533)
                     /locus_tag="ACZPCR_00660"
     CDS             complement(131288..131533)
                     /locus_tag="ACZPCR_00660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012741984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin HicA"
                     /protein_id="HIR1229433.1"
                     /translation="MSQWDKLIMRINRLSKDLRFDELRKILESYGYEMNAPRGGSSHY
                     TFRKQGCAPITIPKQEPIKKVYVEMVRQVVESEAKNE"
     gene            complement(131699..132232)
                     /locus_tag="ACZPCR_00665"
     CDS             complement(131699..132232)
                     /locus_tag="ACZPCR_00665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002568936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HIR1229434.1"
                     /translation="MIRKAAVFAANAHKGAVRKGGNIPYITHPLDTALIVSSLTEDEE
                     LIAAAILHDTIEDAGVTFSEIEGEFGRRVAELVAGETEDKSRSWRERKQATIDRLKGA
                     GRDEKILALGDKLSNLRNTARDYLLDGDAVFERFNMKEKRWQGWYYTSMAEAFKELES
                     FPEYREYVRLCQMVFGE"
     gene            complement(132237..133154)
                     /locus_tag="ACZPCR_00670"
     CDS             complement(132237..133154)
                     /locus_tag="ACZPCR_00670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009244822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HIR1229435.1"
                     /translation="MIFLSTPTQETDAISALGEDLKELQEFGKPDVLMDALKGWVPDL
                     IRFGLNLLVILVIFIVGRKIIRLLLKMARHSFERAGMEIGVTKFIGSLLKFSLNALLI
                     FIIAGQLGIDSASIVAILGSAGLAIGLALQESLKNFAGGILILVMKPFKVGDYIVMPN
                     AEGTVSVIGLVYTILVTIDNKTISIPNGTLSNSIVTNVTAMEKRRLDLTVGIGYQSDL
                     RKAKEIMDRIYRQHPSVLKEEPIVTYVDSLGDDSVVLGARGWTKSEDYWAARWDITEK
                     IKLAFDEEGIEIPYRQMDVHITGSVQDGE"
     gene            complement(133155..135770)
                     /gene="glgB"
                     /locus_tag="ACZPCR_00675"
     CDS             complement(133155..135770)
                     /gene="glgB"
                     /locus_tag="ACZPCR_00675"
                     /EC_number="2.4.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HIR1229436.1"
                     /translation="MDKLLYDLMDWAGIEELVYSESPDPHRILGAHLTENGMLVQAFI
                     PTARNITVRLSGTGKTYPMEMADEAGFFAALIPRKTLTDYTLQVFYDNGTLGEIHDPY
                     SFAPQFTESDLKKFAAGIHYSVYSKMGAHPMTIKGVDGVYFAVWAPCAMRVSVVGDFN
                     FWDGRRHQMRRLGDSGVFELFIPGLSKGAVYKYEIKFRNGDPALKADPYANYAELRPN
                     TASIVWDLNGYEWTDAKWMKERAVSDSKKRPMSIYEVHLGSWKRKEFSLDEAGEAVPG
                     SEFYNYRELAPELAAYVKEMGYTHIELLPVMEHPLDASWGYQVTGYYAPTSRYGTPDD
                     FMYFMDYMHSQGIGVILDWVPAHFPRDSWGMAQFDGTCVYEHKDPRQGAHPHWGTLIY
                     NYGRPQVSNFLIANAMFWADKYHADGIRFDAVASMLYLDYGKNPGEWVANMYGGHENL
                     EAVEFLKHLNSVFKGRKDGAVLIAEESTAWPKVTGNVKEDGLGFDYKWNMGWMNDFLG
                     YMKCDPYFRCHHYGELTFSMIYAYSEDFILVFSHDEVVHGKGSMVNKMPGETFEAKFA
                     NLRAAYGFMTGHPGKKLLFMGQEFGQMDEWNENKSLEWELLEYPIHKNMQSYVKALNF
                     LYREHPALYEEDYMPDGFEWINCMDSANNIAAFLRKTDKPEETLLFVCNFAPVEHEKY
                     KVGVPFPGKYKEIFNSESKNFGGCGIVNPRVKSSKAEECDGREESITVHIAPLGISVF
                     SCTPVKRVKKAARTAGKTAKSKAAGTGRASAAGRSSGAAGGRRTTSAQEKVPESNVIA
                     FKADKSLYGTLADLREDDEAKEALKQAMDGQKKERDESQRKTAQESREKENKNPVVTV
                     IKGAQKALQTGRRSK"
     gene            135955..136578
                     /gene="lepB"
                     /locus_tag="ACZPCR_00680"
     CDS             135955..136578
                     /gene="lepB"
                     /locus_tag="ACZPCR_00680"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015544820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HIR1229437.1"
                     /translation="MENKEKHLGSVRREEAPKSRKRDEEKEPFSWKKEILSWIQILAA
                     AAVIAYVLTTYIIANSTVPTGSMENTIMSHSRVLGSRLTYKFSEPERGDIAIFRYPDD
                     KEEGITTYYVKRIIGLPGETVDIVDGKIYINGSDTPLDEPYLHEEMDMYGKDHLHYNV
                     PEGHYFMLGDNRNNSNDARFWKNKYVPEEDLIAKVYLEYFPNPHFLH"
     gene            136658..137977
                     /locus_tag="ACZPCR_00685"
     CDS             136658..137977
                     /locus_tag="ACZPCR_00685"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HIR1229438.1"
                     /translation="MNKVVKFGGSSLASAKQFKKVKDIIMADKSRRYVIPSAPGKRTT
                     NDEKVTDLLYACYSAASEGRSYKKIFDAITARYEQIITGLDLNVNLDFEFKTIEENFL
                     AKKGRDYAASRGEYLNGIIMAAYLGYEFIDAADVICFDADGSFLSEKTNQELAARLSK
                     VSKAVIPGFYGSMPDGSVKTFSRGGSDITGSLVARAVHADLYENWTDVSGFLVADPRI
                     VDNPEPIETITYRELRELSYMGASVLHEEAIFPVRKEGIPINIRNTNRPSDPGTMIVE
                     STLKRPHYTITGIAGRKGFCAVNIEKAMMNAEIGFGRKVLDVFEKYGISFEHMPSGID
                     TMSIFVQQSLFEEHEQSVIAGIHRAVEPDHIELDSDLALIAVVGRGMKSARGTAGRIF
                     SALAHARVNVKMIDQGSSELNIIVGVRNEDFETAVKAVYDIFVTAEI"
     gene            138114..138674
                     /locus_tag="ACZPCR_00690"
     CDS             138114..138674
                     /locus_tag="ACZPCR_00690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229439.1"
                     /translation="MILNLAAFFIIPGYTLLFIRNFNLFSLNFSVIGNMLGRKRGFCL
                     WGMMTGWYFFWVLSRVSAHLKLSRGVRYLVHTALFLLFCAVTTPYLPEELPFKAFLHI
                     VFAMAAALCLCLYLFLAAWRLRKEDRTAGLVTLWCLAGILLVSAVLLILVGIVSSALE
                     IFFTFSTVFLSRYLYGRTKRLISQSP"
     gene            complement(138655..139092)
                     /gene="rpiB"
                     /locus_tag="ACZPCR_00695"
     CDS             complement(138655..139092)
                     /gene="rpiB"
                     /locus_tag="ACZPCR_00695"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007719500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HIR1229440.1"
                     /translation="MKIAIGNDHSAVELKNIIKEFVESKGYEVINMGTDSTESCDYPV
                     YGEKVGRAVASGEADLGITICGTGVGISLAANKVKGIRACVCSDPYTAKLSRMHNNTN
                     VLAFGARVVGSELAKMITEEWLDAEFEGGRHQRRVDMIMEIEK"
     gene            complement(139197..140144)
                     /locus_tag="ACZPCR_00700"
     CDS             complement(139197..140144)
                     /locus_tag="ACZPCR_00700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006782696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HIR1229441.1"
                     /translation="MKYIGQFHDGMHISDVYLCKKKQIALTKNGKEYGALTLQDKTGT
                     VDAKIWDLGSPGVGNFETLDYVYIDGDITVFQGANQVNVRRIRRADEGEYTESDYLPV
                     SSRDVKAMYQELRALIESMKNPYLKKLASSYYVEDSDFVRRFCFHSAAKSVHHGFVGG
                     LLEHTLSVMKLCDYFAAVYPRLNRDLLLTGALFHDIGKTRELSAFPENDYTDDGQLLG
                     HIIIGTEMVSERIREIPGFPEKLAAELKHCILAHHGELEYGSPKKPALFEAVALSLAD
                     NADAKLETMNEIIAGAGDNNGWLGYNRLLESNVRKTTEF"
     gene            complement(140205..141473)
                     /locus_tag="ACZPCR_00705"
     CDS             complement(140205..141473)
                     /locus_tag="ACZPCR_00705"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1C family serine protease"
                     /protein_id="HIR1229442.1"
                     /translation="MREKIVKPPLTRRQIAARAAVFLLAAAAFGAVSALSFTAVRSWS
                     KDRWEDSSRGESTAIEFNRDDPEAQPEESGSVQESGGLEETVPVDEAVKAYMETYEFT
                     SEDLKSMYDSVRAVEQQADRGIVTVHSGMQQTDLFGNPIETSGYCAGAVIARTSSSYI
                     ILTRSSAVSQADSICVEFFDGTEAPASVLQNDSVTGMAVVLADAAAVDSELRGEIQVI
                     PLGNSYSVKAGDMVIGVGAPAGMVHSSVYGAITYVARNVPVTDGVSRILFTDLTSNGD
                     AGTFILNLNGEMIGWTDNSLKGENSIVSESVMSISDYKGILEKMTNGAETAYFGIKGQ
                     EVSETMQAEGIPKGVYITDAVSGGPAYEAGLQNGDIIVQFDGRDVATLKELSTQIASF
                     QLGNAAAVTVMRKGRDGYTSLEYQVTVRGR"
     gene            141639..141740
                     /locus_tag="ACZPCR_00710"
                     /pseudo
     CDS             141639..141740
                     /locus_tag="ACZPCR_00710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008708342.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
     gene            complement(142233..142736)
                     /locus_tag="ACZPCR_00715"
     CDS             complement(142233..142736)
                     /locus_tag="ACZPCR_00715"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229443.1"
                     /translation="MEEIRKLLEAPDDTKDEFWDSGELIWIDWRDFDDSIINYFNKKL
                     PDEDKIQFECVESEKERGIDIFLKKDGVSRSVPYGDDCTDRDTTLKSIQEYVSPKYQI
                     RWYMESLGSDTLAFCIGLTSQWEQLEQEFGAENVAFYFSPVQADSAMFEMDMDEVFEQ
                     LEQRGEA"
     gene            complement(142804..143211)
                     /locus_tag="ACZPCR_00720"
     CDS             complement(142804..143211)
                     /locus_tag="ACZPCR_00720"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229444.1"
                     /translation="MEKLIILAGSAVINVLFSKGIALGLVLILFWIKGRQLKFNSEEW
                     DNYFLELSQEKVIKIALGIAGSAIAASALISYAILGRAEFHHPFLIAAALFCCSVLWF
                     CHKWRGEKGKAYLLRRFAEIPPVILEKREREKK"
     gene            complement(143199..143414)
                     /locus_tag="ACZPCR_00725"
     CDS             complement(143199..143414)
                     /locus_tag="ACZPCR_00725"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229445.1"
                     /translation="MNRKSFWHSISGSVLILIWTVYYYGMRRTGGVADKTDAVICGIA
                     GFLCAVVIAKKTIEFLKTHKGNKSWKN"
     gene            complement(143416..143886)
                     /locus_tag="ACZPCR_00730"
     CDS             complement(143416..143886)
                     /locus_tag="ACZPCR_00730"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229446.1"
                     /translation="MAFAAVYIITILVVTALFAAAVYFGVKSGRLQYFFEKHSQLPGI
                     LLMGYIIFAGCFVFPIRSEPFPLDFSGVYLLVSSYGVIALASAGIFGPGRGRKVYITT
                     FLITAIGMGCRYLLEFGEVSNTYNFTLFNIVSYLALIPAGTAAAYCWIVRKMRR"
     gene            complement(143909..144244)
                     /locus_tag="ACZPCR_00735"
     CDS             complement(143909..144244)
                     /locus_tag="ACZPCR_00735"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229447.1"
                     /translation="MKKKQLILCIAAILTAAVFLHIGIQRNYTFTLTGSDGGIKSEQI
                     QPLFGTVKVSGDCDTSVLFTDVETGERYEIGYITPGAPEKIRLEKGRWYTAAGAGNLT
                     IGPVRVRIE"
     gene            complement(144241..>144460)
                     /locus_tag="ACZPCR_00740"
     CDS             complement(144241..>144460)
                     /locus_tag="ACZPCR_00740"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229448.1"
                     /translation="VIYGSLYVIALKTGFDFYSYKRYPDIYAAYSAPWYTEALLYGIL
                     SFAVIMACVIVRIIIFRKLAKDTEQVTQ"
BASE COUNT        31656 a        42797 c        32639 g        37368 t
ORIGIN      
        1 taaagttttg attccagtcc aaaacttagc ttggctaatt tttaaaccgt tttactgttt
       61 ttaggttgtt ctgaatgttc tctcgaactt caaggctcct gtgccttttg ttcttagaat
      121 tttcagggtt ttacatactg ttcagttttc aaggttctga tattctcagc cgtttggctt
      181 ctttgaatat ccagcgcaga aggagggatt tgaaccctcg cgccgctact aacgacctac
      241 tccctttcca ggggagcccc ttcagccact tgggtacttc tgctgattga cattttatat
      301 ttaattatct gtcaagagcg gagagagtgg gattcgaacc cacgcgccct tgcggacaaa
      361 cggttttcaa gaccgcctcg ttatgaccac ttcgatatct ctccaaacgt gctcagctat
      421 tatatcacgc tgtttttcat ttgtcaagaa cttttttatt tttctttttg aattttctct
      481 gtttcttcat taaagaaaaa tctttcaaag ccgtcacatt caggctgttt cttttgttct
      541 cagctgccgt tctcagcggc aacgaaaggt attctatcac tgttttcgac agaagtcaac
      601 tgtttttttc aagtttttta tttttttcct gacaaatctg caggagagag aaattcacgt
      661 ctttctccct ctggcagacc tgccttttgg gcatatgaaa gcgccagaac gtgcaggtac
      721 cttctctgct ctgacactac gccttctctg agcagccgct ccgggaaaat ccatagcagt
      781 ctccccgttc cgccaccatt tcatatccta tcgcctctac cagacggcgc agttttgctt
      841 tctcctgcgc tgtactgcat cccatatatg gaccactgcc gccggaacca ggaagaagat
      901 ccatcatcag cacgttagct ccgcacaaaa gccctagtct gcgcccatcg ggaagggatt
      961 tttccagtat ttcagagaca gggagaagta cacggggaag aagaaggcgc gcgatcccca
     1021 tcagatacag cgtcattttt aaagcatcct ctctcgcctc ggccgtctga acactatccc
     1081 cgaaaagaaa tggattaatt tctactattt ctggctgcag ggcacagaga aacatgagct
     1141 cctcagccag gcgctccgga aagccggcaa aggaagccgc acttatctct ccgcccgtct
     1201 gccagccagt tttctttaaa aagtttaagt acctttttct cccgcttttt tcctgctcca
     1261 aagctttcct ggagctgtct cctgcccggc ctgcagcttc agaccgttcc aagcggacaa
     1321 ggtatcgatc tgctcccgcc tgcctccaca tatgaaccgt ttcttccgga tagattcctg
     1381 ccgccagcgt tactgcacag tcagggcagg ctgccttaat ctgttttatc agatctgcca
     1441 gaagcccgcc ctcctgctcc ttctcccggc tcttttcctg gctcttctga agcacgaagc
     1501 tgcgaagacc tgcctgcttt ccatcccggc aggctgaagc cacggcctgt ttcatcaaat
     1561 attcctcctg caaaccgccg ttttgtgaaa aggaacccag ctctgccgcg ccccgcaaaa
     1621 atactctttt cccatagaaa tgttctctga cgcggcgggc tgtacgaaat aaaagaccag
     1681 ctgtttttcc tgttctcacg gaaagcagaa ggatccattc gtctctgctc aaaatctctc
     1741 cgcgggccag ccttgcaatg agccggcagc actcttcctc ctgctgccgg ctgaacccct
     1801 cagaaaacat ctgttccgga tattctattt tctccccaga cctgtaacac tcctgcattt
     1861 ctcccactgg cactgcctcc cccttcaagc tttccagctc ccttttccaa aaggttaaat
     1921 catgccgcgg cgttttaaaa cagccgcagc cacctccata tcctccggcg ttgtcacctt
     1981 aatattttca taggaacctt ctaccagacg caccggaact cctgtcaacc tctccacaac
     2041 catggcgtcg tccgtgaccc cctgctgcag agactcgtcc tccatcatgg tctcataggc
     2101 ctggcagatc aaagaccttg aaaacgcctg aggcgtctgc accatccata ccctggagcg
     2161 atccggagtg gaagctgcaa agccgttttc atctgcaatt tttaccgtgt cctttgacgg
     2221 cataccggcg gcgcaggctc caaattgctc cgccgcctca atggttctgt ctattatttc
     2281 tgaatcaacg aacggacggg ccccgtcatg gatcagcaca atagctgaag aagccggaac
     2341 ctgcttcagt ccctcgcaga cggaatggta gcgttctgca cctccagcca ccactgcctt
     2401 cactttagaa aagccgtacc gctccactag atcctgtctg cagaactcca tctcctgttt
     2461 tcctgtaacc agaatcacct gatccacctg gcttttctca aatgcattta agctgtaaaa
     2521 gagaaccgga taacctccca aatctaaaaa ctgcttctgt attctggttc ccatccgctt
     2581 tccctgcccc gctgccagaa cgatggcgca cgtttgtctc ttcatgacgt cactcccttt
     2641 ccagactttc cagaacctct acctctcccc cagctttaag ttcggaaccg cgtttaaatc
     2701 ccagcctgag cgggcgccct tctgatattc atagtaagct gccgctccta tcatagccgc
     2761 attgtcggtg caataaatag gagacggatg ataaaaccgg attccctcct tctcgcaggc
     2821 ggccttcatg ccctcgcgca gagccgaatt ggaagccacg cctccggcaa tggccagctt
     2881 gtcgtagccg tactccttcg cagccatgat cgctctggat accaaagact ctaccacggc
     2941 gttctggaaa gaagcggcca gatccggcac gcagatctcc tcccccgtca ttttggcatg
     3001 attaatgtaa ttcagcactg ctgattttaa gccgctgaag ctgaaatcat aaggattgtc
     3061 ccctactttt gcccgcggga attcgatggc atgaggattt ccctctctgg cggccttgtc
     3121 caccttggga ccgcccgggt atcccagtcc cacggctctg gccaccttgt caaaggcctc
     3181 ccccgccgcg tcatccctgg tatgaccaat gatctcaaac tcgccatagt ccttcacaat
     3241 gaccagatgc gtatgtccgc ctgagacaat caggcagaca aagggcggtt ccaaatctgg
     3301 attttcaata aaattagccg acacatggcc ttcaatatga tgtacgccca ctaacggctt
     3361 cttggccgcg taggccagcg ccttggcttc cgccactccc accagaagag ctcctacaag
     3421 ccccggtcca tatgtaacgg ctatggctgt aatctcctcc agcgtcacat ccgcctccgc
     3481 aagagcgctc tcaatcacct ggttaatctt ctcaatgtgc tttctcgacg caatctcagg
     3541 aaccactccg ccataaaggg tgtggagggc aatctgagaa gaaatcacat tggaaagcac
     3601 ctctcttcca tttttcacca cagaggcagc cgtctcgtcg caggagctct ctatggccag
     3661 aatcaaaacg tcctcgtttg tctcttgtct attcatgttt cactctctcc taacagctaa
     3721 tcttcatcaa agcccagttc tgcgctccag ccgtctctgg ccgtcttggc gcgggcaaag
     3781 attgctctgg ccttatcagc atactcgtcc ggtctcgtca gggaagggct gtaatgagtc
     3841 agccacattt ccttcggctg cgcctccttg gccaggccgg ccgcctcctg aaaagtcata
     3901 tgcttatact ctctggcctt ggcttccttg ccgtcctccc cgtacattcc ctcgcagata
     3961 aacagatccg cttcccttgc atactctgca attaccggaa ccggcctggt atctgtacag
     4021 tagaccacct tgattcctct tctggccggc cccagaacca tatcaggcgt cagaagacgc
     4081 ccttcctcct caatggtttc tcccttctga agacggttcc agaatctctg gggaatatcc
     4141 tgctccctgg ctctgtccac atcaaacttt ccttttctgg gaatagacac cgcatagcca
     4201 tagcagatca cattgtggtt gacgcggtaa gcgtctatga tgtaaggacc tatctgaagc
     4261 tgttctctct gctctgtcag ctcaataaac cggagttcaa agggcagttc cggcgcaatg
     4321 gtcctgagag cgcctactac acgttccagc cccttaggtc ctatcatggt caccggctct
     4381 gtccgctctg cgtttcccat ggtaagaaga agccccggaa gaccgctgat atgatctgca
     4441 tggtaatgag taaagcagat aatatcaatg ggcttgggac tccacccctt ctcctttaag
     4501 gccacctggg ttccctctcc gcagtcgatc agaagattgc ttccgtcgca ccgggtcatc
     4561 agggatgtga gccaccggta gggaagaggc atcatccccc ctgtacctaa cagacaaaca
     4621 tctaacatat aaaaaaattc ctctctgttt tctttttcgg ttctgcagtt ttgactttac
     4681 atgaaacgaa acgtttctat aaagcgaaaa agaacgaaga accctgccgc gcaggattct
     4741 tcgcctgatt ttcaaaatca tgccgcctgg ttttaccccg caggctcatc cggcgccgcc
     4801 ggctggcata actactgaaa ttcctttcga aggacttcct ttggcatctc tatctcgcct
     4861 gcaatcgtat gctccgtcag ttcagacagc agtttgattt tctggttcag aacaggccgc
     4921 atacagttcg gcacatgctc ctggtgcgct ctgtggattg ctacgcattc cttacaattc
     4981 ccatgatagc ggcaggcctt tttgcatgga caatgatcct tatccttgta ctcctctcta
     5041 aattcagagg caaactcttc ctgcagctta aggccctgcg cacggtttcc cttgtgaaat
     5101 tccgccatcg ccgcaagctc ctttggatta tgttcaatca ccatcacagt tcctcctatc
     5161 cggcagttct tttctcttac agttccttct tatttatcat atcacaaaga aaaatttttt
     5221 tctatcctgg agcttagatt ctacaaaagt tccgtccgct cttttacctg aacagaaatt
     5281 ttaaattgat tggtcagctc gtcataacac gattcgcaga gatcaaagct gtggacttct
     5341 ccgtcttttt ccgaaaaata atcccaggta agctcaaaat gagcgcttcc ctcccgcaaa
     5401 attccatcct tcacaatcag gcgctttccg caccagttgc accacaccga ttccagctct
     5461 cccttgcctt tgtattttct catgtttcct cacctttctt ctatcgccga acgtttcccc
     5521 gtttcctgtt aagcggactt ttcatttcgt ccagatggaa ctcctatgaa atgaaaaacg
     5581 gggcatccga aacggatacc cctaaattat aatcgttctt atgcctgttt ttaagtggta
     5641 attatttcaa gaaaaataga gccacataat gagagcgtcc tcagccggat tctcataata
     5701 attctttctg accgcttcct ccccgaaacc ataggattta taaagctcaa tagccgtccg
     5761 gttggatttt ctcacctcca gggtgagggc ctctgcgccc ttttctctgg cagtctcctc
     5821 cagctgatcc atcagttttc tggataatcc tctgccgcgg agctctggat gcacagcaat
     5881 ccgcatcagc tcgccctctc cggcaatcac ccgcagattg cagtagccgg ccagacccct
     5941 gccgcaatgg ccgccttctt tttcctgtcc gcagtccccg ccggttctgt tatctgccgg
     6001 ttccagaacc cagagaaaat ccagccggct ctccagactc tcctgcagga tcgcctcaga
     6061 ccatggcgct gaaaagctta accgttccag ctctgccgca gcggccagat ctctctcctc
     6121 cataggccgc agggaaaatc ctgtctctga tcgattcatg tttccgcttc cctctttcct
     6181 gtctccgttt cctgttctgt tcatatccgc gcgatgtttc tgcctacgcc tgcttttcca
     6241 ctacctgaat tccggcagcc agcttgtcca gctctccctg gcgctccgcc agttcccgtt
     6301 ctctctccgc ctgggatttt ctcaggtaat ccggcttgtg ctccatggca gtttccgtct
     6361 ttccctccgc caggtaaacg ctgccaaggg ctgccacaga agcggctctc tgccggttta
     6421 catgagctgg ggcaaacctg tggggaacct ttatcagctc ttcgataacc gcctgataag
     6481 gaggcactcc gtctcccagg aatatcaccc gctctccccg gccgtttaac tcctccacaa
     6541 gctctttaat atccgctggc tgctgctcct tcacgatctc aaactcttcc cggaaatgat
     6601 acagtcctgt gtaaacctga tttcttctgg cgtccataat cgggcagatt aaagcgtccg
     6661 taccgtagag attgtacgcc atagcgtcca cggtgggaac gtggatcagg ggctttttca
     6721 tggcgagccc cagccccttg gccgtagcag atccgatgcg cagtcctgta aaagaaccgg
     6781 ggccgccgga tacggcgatg gcgtcgatgg tatccagctc tatctccagc atccggatca
     6841 cctcgtcaat catgggaagc agggtctggg aatgagtttt ctttaaattt accgtatatt
     6901 ctgccgtcaa aattccatct gtcacaatgg ccacggaagc caccagcgac gagctttcaa
     6961 ttcctaatac tctcattgtc tctcctccac cgttattttc cggtaatcaa agcccttttc
     7021 cagatccttc tcaatcctga tttcaatggc tgtctccgga atgatctcct ccaccaggga
     7081 ggcccactcg atcaagcaca caccttctcc gtaaaagcag tcctcatatc cgatttcatc
     7141 catctcgctg atatctccaa tccggtagac gtcgaaatgg tagagcggaa ggcgcccctc
     7201 ctcgtactgc tgaatgattg tgaaggtggg actgttcaca tcactctgaa ttcccagtcc
     7261 ctttgcaaag ccctgggtga ataccgtttt tcccacgccg agatcgccgt ctaagcagta
     7321 aacctgcccc ttccctgcct gctctcccag ccgtttcccc gcctgaaagg tctcttcggg
     7381 gctgtatgtt tcaatgattt tcataatccg gttcctttcc tgtttctgca tttaatctta
     7441 ctatcctaga cgccggtatg tcaaccggaa cagaaagaag ggctgcgcca ggcagccgat
     7501 ttctcagccc cagatcgcag ccctcctgct gtattataca taatttccag ccagcgtccc
     7561 ttatatctcc tcgttcagct tcgccagctt agcggcctga tcagccgcaa tcaggctgtc
     7621 gatcagctcg tctaaatctc cgtccataac cgagtcaatc ttgtagagcg tcagcttgat
     7681 tctgtgctct gtgacacggc cctgcgggaa attgtaggta cggatcttct cagaacggtc
     7741 tcccgttcca atctggcttc ttctggcctc agactcctcg ttctggcgtc tctccagctc
     7801 taaatcgtac agcttggagc gcagaaggcg gaaggccttc tccttattct gaagctgtga
     7861 tttctctgtc tggctgtaga ttacgatacc ggtaggcata tgagtcagac gcactgcaga
     7921 gtcagtcgtg ttgacgcact gtccgccgtt tcctgacgcg cgcataacgt caatgcggca
     7981 gtcgttcata tcgatctcaa tatccacgtc ctctgcctcc ggcatcacgg ctacagtggc
     8041 tgtagaggtg tggatacggc cgccggactc tgtctccggc acacgctgta cccggtgtac
     8101 gccgctctcg tacttgagct tggagtaagc gccctggcct gttaccatga acactacctc
     8161 cttgaaacca ccgattccat tctcgttcag gctgacaatc tcagtcttcc agcgctggcg
     8221 ctctgcatag cgcacataca tacggtacag ctcggaggca aacagagccg cctcgtctcc
     8281 gcctgcgcct gcgcggattt ccaccataac gttcttgtca tcgttgggat cctttggaag
     8341 caggagaatt ttcagttcct gctccagctc ttcgattctc tttttcgcgt cagccagctc
     8401 ttccttggct aactctctca tctcctcgtc agactcttcc tccagaaggg caacgctgtc
     8461 ctccacgtcc tgatgagcct gcttgtaatt cttatatgcc tctacaatcg gagccagatc
     8521 cgcctgctcc ttcataagtt ttctaaattt cttctgatcc tcaaccacat atgggttgtt
     8581 gagttcttcc atcagttcct cgtatcggat cagcaaatcg tctaaacgat caaacatggc
     8641 aacctcctgt tttactattc cttccttaac gtccggcagc ttccgctttc actacccggt
     8701 ccagccccgg cgcatctttt atcacctgta tattcctgta accattctcc tcaagaagcg
     8761 ctgtcacagc cgccccctgg tcgtgtccaa tttcaaaata aacccgtcct cccggcttca
     8821 gatggcgtcc gcactcttct gccagacgcc tgtaaaaata caggccgtcc tcccggccgt
     8881 caagcgccag ccggggctcg tgttcccgca cctctggttc caggctgtcc acaaccgccg
     8941 acggaatgta ggggggattc gacacaatca catcatagag acgcccgtca tccgctgaga
     9001 acagatcgct ctgaaacagg gaaaagctcc gctcctccac ctccagagga cgtcctgtcc
     9061 tcggtctgtt tccgaatatt ccggctccat ttcggccctt ctccgcctcc ccggtccaaa
     9121 cggacagttc catcctccag ggctgatcag acactttttt cgactgggag cggataacat
     9181 tcttctgtat cataaaaaga tttctggcgt tcttcagggc aattttcaaa gctccttctg
     9241 agatgtctgc cgccgaaacg ctcctatatc ttccaagcac cgccagactc agcccgatac
     9301 agccgctccc ggtgcacaga tcgagaattt ccacgtcgcg gttctgacag tcttttaaaa
     9361 tctcctccac cagagtctct gtatcctgcc tgggaatcag cacctggtca ttgacctgga
     9421 aggaaagccc cataaactcc tggcagccca aaatctgctg aagaggaatt ctgagagccc
     9481 gtctcccaat gcgctctgca aaaactggcc accctttttc aaaggttccc ggatgcacag
     9541 ttctgtttct gtccatcagg aaatgcactc tgtctacgga aaagctgtcg gaaagcaggt
     9601 accaggcgtc cagctcggcc tccgccactc ctgccgctga aagtcttccc gccccggcgt
     9661 ccagcatctc ctgccaggtt ggcagttctt caaaaggccc ttcaaaaagg catgctgtca
     9721 ctgtacggtt catgcgtccc tcctgagagc ttcctctttc tcctggctgt cttccgaatc
     9781 ttcaaaagcg ctcagatcgg tatccgggaa attctccctc agatacgcct tccagtcaaa
     9841 cacagcctcc gtggcggcga tagccacctc tatcatggaa tcgtccggtt ccctagtcgt
     9901 aaggccctgc atccacatac ccggacggct caccagatcc ataaatcttg aattgctccg
     9961 gccggccagc tgcagaatct cgtaggacac tccggcaatc accggaacca gcacaatgcg
    10021 gctggcaaaa cgcatccaga cattgtccac tctgactacc atgaaaaaca gaatgctgat
    10081 gaccatgaca atcaggataa aactggttcc gcagcgcttg tgctccttgg aactgtttct
    10141 gacattttcc acagtcagcg gaaggccgtg ctccacgcag ttaatgcact tgtgctccgc
    10201 tccgtggtac ataaacgtcc gcctgatatc ctccatacgg gaaacaagct taatataggc
    10261 aatgaaaata agaatgcgga ttatgccctc cagcactgcc atcaggcgtt ccgactcaat
    10321 cacgctggaa aacagccctg cgataaaaag cggaagcagc atgaaaatcc cgatagccat
    10381 gacaaaagac agaaccatga cgagagccat cagggcgctc tccagcttct cccccagcac
    10441 ccggttcaga aattgctcta tctttcccgg ctccgaatcc tcgtcgtcct caaagaagct
    10501 ggcggaatag gtcagcgtct tcatacccac aatcatggaa tccgcaaagc ggaatacgcc
    10561 tctgacaaag ggcagggaga acagcttcac cttttgggta atgctgatat accgatccct
    10621 tttaacctct atttcctggt ccggtttcct gactgccacc gcataatcgt tccggttcat
    10681 catcatgatc ccctcgatga cagcctgtcc tccgattcct gaatatttca tatgatttca
    10741 tttctcctta tgaaaaccaa aaaggctggg tttcatgtct ccattaaaac ccaaccctta
    10801 tttagccaag ctattagttt gcgctgatgc cgtacttgcg gttgaactta tcaatacgtc
    10861 cgcgggcagc tgcagccttc tgctgtcctg tgtagaaaga atggcacttg gagcaaacct
    10921 ccacgtggat gtccttcttt gtagaacctg ttacgaactc gttgccgcag ttgcagacaa
    10981 cctttgcctg ataataagct ggatggattc cttccttcat gattttcacc tctcaatttt
    11041 tcttctgtgg tttccgacca cacgtacaaa tgtaccaaaa ttttctgccg cgcagtgtgc
    11101 ggctctctgt ctgccgtgca gtaattctac gatacacagc ttacacagta tagcacagaa
    11161 agccctctat tgcaagggat tttttcgttt ccccaagaga aaacgccaga aaaacacggc
    11221 ggttctaaat ccgcactttt ttcaccatat ccacaaattc cctgttgttc ttcgttctgg
    11281 caaacaggtc taaaatccgc tctaccgatt cctccggctt cgccgtattg gtggccttgt
    11341 ggataatatc caccgcctcg gtctccagag gattcaaaag cagatcgtcg cgtctggttc
    11401 cggattttaa aatgtcgata gccgggaaaa tccgcttctc ggacagcttt ctgtccagga
    11461 caatctccat atttcccgtt cccttaaact cctcatagat cacgtcgtcc atacggcttc
    11521 ccgtatcaat cagggcggta gccagaatgg tcaggcttcc tccctccctg atatttctgg
    11581 ctgcgccgaa gaagcgcttg ggcatgtgaa gagcagccgg atccagaccg cccgacaggg
    11641 tgcggccgct ggcgggcact accaggttgt aggctctggc cagacgggta atgctgtcga
    11701 ggagaatcat aacgtcgcgt ccatgctcca ccaggcgctt cgcccgctca atcaccatct
    11761 cggacaccct cttgtggcgg tccggcagct cgtcaaaggt agagtaaatc acctccacat
    11821 tcggccccgt gatggcctcc ttgatatcgg ttacctcctc cggacgctcg tcaattaaca
    11881 gaatcatcag atgcatatcc ggatgattga cagttaccgc cttggccacc tgctttaaaa
    11941 gagtagtctt tcccgctttc ggcggagaca caatcatgcc tctctgtccc ttgccaatcg
    12001 gcgacagcag atccagcacc cgcatggctg tggaatttct cgttcccggc atctccatat
    12061 gaagcctctc gtccgggaaa atcggcgtca ggctttcgaa attaggcctg cgctctacca
    12121 cgctggtggg atatccgttg attgtctcaa tatataaaag cgccgcaaat ttctctgtag
    12181 ctgtcttgat cctcctgctt ccctggacaa tatcgcctgt cttcaggtta aagcggcgga
    12241 tctgggatgg ggccacatag acgtcgttat ctccgggcag gaaattttcg cagcggataa
    12301 agccaaatcc gtcggacata acctccagaa ttccttttgc ctcgattccg ctgtccagtt
    12361 cctgcagatc agccttcaca tcctccactg tattttccct gtactcgtga attctgttct
    12421 cttgatatcc gctctcctgg attctcccct gctgataccg gttttcctga accctgctgt
    12481 cctggtaacg ggcgtcctgc attctgccgt cctggtagcg gctctcctgg gctcttccct
    12541 catttctcac atcgcttctg tctgccccct gctggcagcc gccttcctgg cttcctgcat
    12601 gaacaccgga gttgttctgc ggataactgc gtccggaaga attcctgtaa ttgtttcctc
    12661 tgtaattctg gctgcctcta taattagaat tgttttcgtt tcttccatag tttctctgct
    12721 ggtaagtcct ggccgggcgc tcctcctgct ccggcgtttt ttccctggca ggttctgccg
    12781 gacgttccct gtaagactcg ccttctccag ctctctccgg catatggaca gccgccttat
    12841 caactgcctt atcaggcgtt ttgtcgtccg ttttttcgca caaacgctca atcaactctg
    12901 cttttttcag agttgtcact cctttaatcc cctgggtctt tgcaagctct ctgagctgaa
    12961 caagaggcag agtctgaagt ttctctctca tataccactt ctccttattc tgttattcac
    13021 gctgatgttt gtcattctgt tatggtttct tactgattcc tgccactccg gctgtatttt
    13081 ttgatctttg tacgccaaaa acagcggctg cattgaattt atacgattac tttctttctg
    13141 gggattgtat agaattaaga cgggttccca gcttcagcat acggaaatct gcctctgtcc
    13201 cttcccggca gagtcttcct tttatgcttt tgcacaaaat tattatatac cattctattt
    13261 ggaattgcaa agattttata tttttttcac atctcgtctg cgcaaatgtg gtatgatagc
    13321 agaagggaag cgcaggaatc ccctgtcccc cgacagaaaa caaacgacat ttcagtgaaa
    13381 ggaatggtga ctatggatta tttgacaatg accattggaa aacagaaaaa cattgccctg
    13441 attgcccacg atcagaaaaa gcgcgagctg atcgactggt gcaatgcaca taaagaagtg
    13501 ttgaagcatc attttctctg cggaaccggg accacggccc gcatgatcac agaggccacg
    13561 gagcttcccg tgaagggcta caacagcggt cctctgggcg gcgatcagca gatcggagcc
    13621 aaggtagtgg agggacgggt ggatttcatc gtcttctttt ccgatcccct gacagcccag
    13681 ccccacgatc cggacgtgaa agctttgctc cgcatcgctc aggtatacga catccccatc
    13741 gccaacaata aggcgactgc cgatttcctc attacctcca gctatatgaa ttcagagtac
    13801 gagcaccggg tcattaattt ccaggaaaac atcgcaaagc gagcgaaaag cctgtaaatt
    13861 tcacaggaga ccattttcta tgacgtcaaa agagccctct cccgaatttc ttcaggagag
    13921 ggctccaatt tttatatctg ccgcaattaa tttgtcagct ttgctacgtt taacttcaca
    13981 cctggtccca tagtggatgt cagtgttacg ctcttgaagt aagcgccctt taatgtagct
    14041 ggctttgcct tcagaactgc gtcgataagc gtctggaagt tgtccgctaa ctgctcctct
    14101 gtgaaagaag cttttcctac tggcacgtgg ataatgtttg ttttatcaag tctgtactca
    14161 atcttaccgg ccttgatatc gttgatagcc tttgtaacgt ccatagtaac tgttccagcc
    14221 ttcgggtttg gcattaagcc cttcggtccg agtacacgtc ctaaacgtcc tacaacgccc
    14281 atcatgtctg gtgtagctac aactacgtcg aaatcaagcc atccctcgtt ctggatcttc
    14341 ggaattaact cctctgctcc tacgaaatca gcgcctgctg cctgagcctc gtcagccttc
    14401 ggtcccttgg caaatacaag gattctgaca gtcttacctg ttccgtgagg aagaactaca
    14461 gcgccgcgga tctgctgatc agcgtgacgt ccgtcacaac cggttctgat atgagcttca
    14521 attgtctcgt caaatttagc acctgctgcc ttcttaacga tagagatggc ttcggatgct
    14581 tcgtaaagat ttgtacggtc tactaactta gcagcctcta cgtatctttt tcctcttttc
    14641 attataaata acctcctagt ggtattgtcg gggattgccc tcccacgttt ctaattcaac
    14701 atctcgttct gcagacagta aggaatcctt actcctctac tgtgataccc atacttcttg
    14761 cagttccggc gatcatgctc atagctgctt ctacgtttgc tgcgtttaag tctggcatct
    14821 tgagctcagc gatctttctg acctcatcct tggagatggt agctaccttt gtcttatttg
    14881 gtgttgcaga gccggatttc agcttgcatg ccttctttaa taaaacggca gccggcggag
    14941 tctttgtaat aaagctgaag cttctgtcag catatacagt gataacaacc gggataacca
    15001 ggtcgccctg atctgctgtt ctagcgttga actcttttgt aaactgtacg atatttacac
    15061 cgtgctgtcc aagagccgga ccaactggcg gagctggtgt tgctttacca gcaggaatct
    15121 gtaatttaat atatcctgtt actttctttg ccatgataag gcacctccta atattgtggt
    15181 aatggcggga tgaaccctcc cacgagcctg cgaaacacag gccgcatctt acatcttctt
    15241 aacttctgtg aagtccagtt caaccggtgt ctcacggccg aacatctcca cggtaatttc
    15301 aagtgtctgc ttgttatcgt tgatggactt gataacacca acggtatcct tccaggcacc
    15361 ggagataacg acaaccgcat ctccaacctc gtaatcaacg actactccgg ctggtttgaa
    15421 gccgagattt gccatctcgt cctctgttaa aggaaccggc ttggatcccg ggccaacaaa
    15481 acctgttaca ccgcgggtat tacgcactac ataccatgtg tcatcgttca taaccatgtt
    15541 aataagcaca tatccgggga acatcttttt ggcaacctgc ttctgggctc cattcttaat
    15601 ctcgactaca tcctgcatgg gaacggatac ttccaggatc tgatcctgaa ggcctctgtt
    15661 ctcaatggtc ttctcaatgt cgacctttac tttgttttca tagcctgagt aagtgtgaac
    15721 tacataccaa ttcgcttctg acataatctc accctatccc ttgtgtgtgt tagatgatat
    15781 agtgcagcag gaacacaatc gctgtgtcta aggctgcaat gatcagacct aaagcgacag
    15841 ctcccgagat aacggctgcc gtctgcttct gaagggttgc tttgtcaggc cagattatct
    15901 tcttgtactc agccttgagg cctttccaaa agctcttctt gggggccttt gcggtattcc
    15961 ctgtttcacc cattctttgt cctccaaaat gttcaagcga acgcctgatc ctttatactg
    16021 gcacgaagat tattttgtct ccttgtgcat agtatgtctc ttgcagaatc tgcagtactt
    16081 cttagtctcc attctgtccg gatgagtctt cttatccttg gtcatgttgt agttacgctg
    16141 tttgcattct gtacatgcca gtgtgattct tgtgcgcacg acttccacct ccacttaaat
    16201 tcaaattttt tcaggcttct cctcatgctt ttgagcataa aaaaaagacc tagctcttcc
    16261 attcgcccgt ctactatacc ataaaactct ggattcgtca atattttgtt ttgaaatttc
    16321 gcgctggaag atataccttc ttaaatcgat gcacgaagaa aaaatttcct tgttccaccg
    16381 aaagtcaccg gaaatttttc ctcgtgcata ctttttggca gcttccagcg gaacaaaaaa
    16441 tggaacaaga aaatttttcc cctggacata ctttcccggc ctctatatct gcgttctgac
    16501 gcactccgct ccaaagggca tcagggccag cttggccagc ttgaactgct ggaggccaaa
    16561 gggaatgccg atgacggtca cgcagagcag aaggcctatc agagcgtgct ccagagccag
    16621 aggaagccct gacagcacca gccagattaa gtttaccaga aatgaaactg cgcctccgcc
    16681 gtatctgacc tctttcccaa aggggaaaaa gctcagggaa gccagcttaa agcactgaag
    16741 ccccaccgga attcctatga ttgtcacgca ccacaggcac ccggccagac accagctgag
    16801 gccgctgata cagccgccga agataaacca caaaatattt cccagacatc ccatcgtttc
    16861 atttctccct tcttctcatc tgctttcact ctgctgccgg ccgctttatg attcctggtt
    16921 ccatacaatg gttcccactt tccacgttcc gctctccgga tcctcccaag ccaggcacag
    16981 gtccttcagt ttctccccgc ggctgcagag aaatacctcc gcaccgtctg ccgtcaccgt
    17041 ccgatcccag acatttgtta tctcctgttc ctctttcagc cgattcaaac gctcttcccg
    17101 atccgcctct gctgccggct ttctgttctc ctcttcgtct ctgatttcac gaagcatctc
    17161 gtaaaaggca agtttctctc ctgcatcctc ttctgacaca tcccgggcaa acagctgtcc
    17221 cgtttccatc acaatgtgat actctttttc tatattcccg ttctccatct ggtatacaaa
    17281 aaccgttcca ttgtttgcaa acacttccgt cgactgttcg tccttcatat aagaatcctc
    17341 aactgccttc atatccgccg ccgtccctgt gcgccacaca gattctccct cctggcgggc
    17401 cagcacagcc gtaccccaga ggccatgaat caccgctgcc gtccgttcct ccggattcgt
    17461 cagctgctct ccgttttcgt cggtcagctg cagatagctg tgtacgctgt ccaggtaaac
    17521 gcggcctgtt ttgtccgggt caatcagaag ctcctgcgcc tgtccggaaa aagacgggca
    17581 gccggaaatc tcctctgcat ctgtcatttt tcccgccaca aaaacggagg cagggccgtc
    17641 tgctccgccg ataatactga cggcatgcat atcttcctcc tgtccttgcg ccgtctcctc
    17701 tgtcctcatc tgcgtctctg ccgcagtcct cgtttcatct gcctgttctg cctgacagcc
    17761 agtgcagaga gcagacgcag caagcattcc caccattccc acccagactt tccgtttcat
    17821 cctgtctctc ctctcggtat tcttctgctt atcatctgcg aaacccatat ttcccaccgt
    17881 ttaacagtta tcccatattc ccggggctgt acgcaggaag ccccccgccc ccccggctca
    17941 atggttctga ttgtaatgta gcacacggaa agcagaaact gcaaggatca aatttcttac
    18001 attttccgat atttccagaa agaaaaaacc tctgccggct gtcctgtatg ctccggcaaa
    18061 ggttctcttc caagatatca aattaaaaat tcgtagttga ctatgtctaa cagctgcccg
    18121 aacttctcgc ctgcccggtg catggttccg cagtaggaaa agcccatttt ttcatgcaga
    18181 cggatgctgg cttcgttatt tcccgtgata acggatatga cagtgtgaag cttcccgcag
    18241 ctgcgggcca tatcaaggag ttccctcatc agcgcttctc cgattccctg tcttctgaaa
    18301 tcccgtgaaa catagacgga aagctccgca gtccctttgt aagcctcgta agggcggtag
    18361 tctgacaggc aggcgtagcc cgccacgcgg ccatcctgct ctgctgcgat taaaggatga
    18421 cgttctccgc cgtgagacca aaaccacgcc agacgttcct cataggattg ttctgtaatg
    18481 gcgaaggagg cggtggaatt tctcacctca taattaaaaa tttccatcat ttcccttacg
    18541 tcctcctgga cagccgggcg tattttcata tggatcactc ctcttcctga atctcagccg
    18601 tctcaggtgc agccggttcc tctgtcccgg aactctcctc ctctccatcc gacggagcta
    18661 agatatgggc catctggccg atttttccga ggccttccgt atttttattt ctcactacgt
    18721 agccttcctc ccagacgcgg ctgcttctct ccctctccgc ctcgtcctct tcgttttcca
    18781 gcttatagtt ctccggatga gccttggcgt cctccatctt ttcctggaga aatgttttaa
    18841 acgcttcctg ctcttcctgg cttgcaaatg ccttcttcgc cacaaactga tatccgccgt
    18901 cagctgtctt taacagaatc aggcgttcca gctccagaat ctcagacaga gctgtgtact
    18961 ggtaatgcat ctgctcttcc gcccggttgg aaccgtacag gtcaaagccg tcctccctga
    19021 gaaccaggtt taccgtagga aagcctgttt tctccatctt tttcagcccg cttttcttat
    19081 aaatcattct ctcctgattc tgcggagagg taaaatagag catgatagct cccaggccca
    19141 gaaacatgat ggaggaacca accgccgctg ccagaggcgc gccggaggaa agatttccta
    19201 tcagagtcat tgccagaagc gccatcatga cgcccaccgt aatatagcgc acttttttct
    19261 gatcatgctt tttgatgttc cactgaatcc actctctgta atcatctttt tcaagctgat
    19321 acgtatattc cttcatttct agctccttcc ggagaccttt tcccccattg cggcgggaac
    19381 tgtctccaaa tttttgactt atctatcatc atatcgtatt tttctgtctg tgtccaatgc
    19441 aaatggcaga aaatcacaga gtgggcgcag gaatttatgc tccatgtccg atgcagacgg
    19501 caaatacaaa cacctgcttc acccccgttt taagaagggc tctggagcag atctccgccg
    19561 tgctccccgt agtatagata tcgtccacca gaaggacccg ttcccatttt cccgcctcct
    19621 gctccgcctc gaatgctccc ctcagatttt tcaggcgctc tgcagagccc aggcttttct
    19681 ggggatctgt cttttttaca cggatcagca gctcctccca tggaattcca agctcagccg
    19741 aaagcttctc agccagcacg gccgcctgat tgaaccccct cgtcttcagc ctggaagcgt
    19801 ggacgggaac tggcacaatc acctggattc ccgcctgcct gaactgcttt tcaaaccgca
    19861 gagccgccgc cctggcgtag aaatccagat actctctctt attgtgatat ttgacggcag
    19921 ccatggacac ggcggccctg ctgtcgtaat tgagcagggc gaaccccctc gtaaagctct
    19981 ttttccggcg gatgcagtcc gcgcagtatt cctgctctct gcttccgatt tccttgccgc
    20041 acttcatgca ggctggggac gatacaaatg ataactgttt gagacatgcc gggcagatca
    20101 gacgcccttt cggcatcgcc acgccgccgc acaccgggca gcggcgcgga aagagaagat
    20161 ccgccgctgt ccggcaggaa tactcaagaa atgctttgat gtgatttgaa tgcttgtcat
    20221 tcatagaaat gcagattctc ctatataaga ctttcctcta tctcctgaat tctgtccttt
    20281 aatccacaat atctcttctg ctgggacgcg ttatccacca tggactgaaa tacctgtgga
    20341 attcccacca ggcagacgca ggacttggct ctggtcacgg ctgtgtaaat tagattcctg
    20401 gtcatcagca tcctggggcc tggataaatg ggcagaacta ccgccggata ctcgcttccc
    20461 tgggatttgt ggatggtgat ggcgtaggcc agctccagct cctccagctg cttaaagctg
    20521 tattctgcca ttttcccctc gtcgaactcc acggtcatga gctcggaaaa tgtattaatc
    20581 tcccggataa tgcccacatc tccgttgaac acgccggagc ctttatccac cggcacgccg
    20641 tacctgtttc taagctccca ctccatctga taattgttct taatctgcat caccttgtcg
    20701 ccggtgcgga aaatcgtccc gccgctctcc ttctcctttt tctccggaga cggagggttc
    20761 agatacttct ggagaatctc attgagccgc tctactccca gagcgccctt tcgcataggc
    20821 gtcataatct ggatgtcaaa ggtgtccgcg tgaacgtagc ccggcagctt ttcccggacc
    20881 agagtgataa tcgaacggac aatggcattt ggatcctctt ggcggataaa gaggaaatcc
    20941 tggctcctct tgcccagagg aatctgtcct ccctcgttaa tcctgtgggc gttcaccacg
    21001 atatcgctct gggccgcctg gcggaaaatc ctggtcagct tcaccacatg aaagcactga
    21061 gactctatca tgtcgcggag cacattgccc ggtcccacgc tgggcagctg atccacgtcc
    21121 cccaccagaa tcaggcgggt tcccacgctc accgcccgca gaagggaatg catcagatgt
    21181 atgtccacca tggacatctc gtcgatgatg atcacatccg cgtccagcgg gttttcctca
    21241 ttccgctcaa accgcattcc tgcgttggcc atcttgctcc gctctcccgc gtcgcctgtc
    21301 ttctcctcca caggggctcc ggaaagctcc agaaggcggt ggatcgtcct ggcctcaaag
    21361 ccggtggctt ccgtcatgcg cttggccgcc cggcctgtgg gagccgccag caggatatcc
    21421 aggccgccca gctcaaaata gcggataatg gtattgatcg tcgtcgtctt tcctgttccg
    21481 gggccgcctg tgataataag gaggccgcag ttgaccgctt ctatgaccgc ctgcacctga
    21541 agctcgtcca gctcaatgtg ctcctgctcc tgaatcgtct tcaggctctt tcggatggac
    21601 tcctctggct gatcccccgt gatattcaga tcgtgaagca ttttggccgt gttcagctct
    21661 gtgtagtaat actgggaggc gtaaaccagc tgtcttccct gatccgtctg ttcctcccag
    21721 gcttccccgt ctccatccag gcttcccgga agctcttctg cctctttggc aggttcttcg
    21781 tgcgcagcct gttccctgcc ggtttcctcc ctggatcgtt tcaccaccag acgcttttcc
    21841 atctgcatgt ccatgaggcg gttctcaatt tcctccggat ccacgcccaa aagctccgcg
    21901 gcctgggctg tcaaaatctc cttcggaagg tatgtatggc cgtttcccga cgccctgaaa
    21961 agcgtataca gaattccgct cttgattctg aaatcggagt ccgtcagaat tccggccctg
    22021 gcggcaatct catccgccat cttaaagccg actcccggaa tgtcgtccgc cagcttgtag
    22081 ggattctgct taataatccc gtacatggcc gggccgtatt cccggtagat tttcgccgcc
    22141 agattcatgg acacgccgta gtcctgaagg aacatcatgg cctggcgcat atcccgcttt
    22201 tcctcgatct gctccccgat ggacatggcc atcttttcgc tgatcccctt gatctctgcc
    22261 agacgctccg gctcctcctc catgattcgg aaggtgtctt tcttaaattt tttaactatc
    22321 cttgaagcta aagcagcccc gatgcctttg atggcaccgg agcctaagta gcgttccatg
    22381 gatacagtgt cctcgggagg cttaatctca tagctctcca cagacagctg ttccccgtaa
    22441 acgggatgtt ccgtcatatg gccggacgcc tccagaagct ctccctctcc aatgaaagaa
    22501 aaattcccaa ccaggatata ttcctccccg tcgtcggagc ctgtgaggct aagaaccgta
    22561 taaccgttct cctcgttccg gtatttaatt ttctcaacaa aacctttcac tgaagccata
    22621 tctgctccta gtcaaaattt ttggaaccct ctccgtgaag gaactcaata aactttcctg
    22681 ttccgatagc caccgctgtc agaggatcct cggcaatcat ggtcgtaatt cccgtcttct
    22741 cctcaatcag ggcgtccagg ccgctcagca gcgctccgcc tcctgtcagc acaatgcccc
    22801 ggtcgaaaat atcggcggcc agctccggcg gagtccgctc cagcacgttg tggacagcgt
    22861 ccacaatctg cagggccggc tctctcaacg cctctaaggt ctcgtcggaa gtaaccacaa
    22921 tggtcttcgg aagtcctgtc accaggtttc ttcccctgac ctccatcgtc agcatctccg
    22981 gtctctggta agcggcgccg atattgatct taatctcctc ggcggttctc tcaccgatta
    23041 acaggttgtg cttcttcctc atgtagcgca ccagcgcctc gtcaaagtcg tctccggcaa
    23101 tcttaatgga agtgctgaca accgtgcctc ccagggaaat cactgcaata tccgccgtac
    23161 cgcctccgat atctacaatc atgtttccgc aggccttgga aatatcaatt ccagctccga
    23221 tagcggccgc taccggctcc tcgataatgg ttacgtctct ggctccagcc tggtaggtgg
    23281 cgtcctctac tgcctttctc tccacctcag tggctccgct ggggatacac acgctgattc
    23341 tgggctttct caaggttctc tttcccactg ccttattaat gaaatatttc aacatcttct
    23401 ctgtgactgt atagtcagag attacgccct ggcggagagg acggaccgct acgatattgc
    23461 ccggcgttct tccgatcatc agacgggctt cctctccgat ggccttgatc tcgttcttgt
    23521 cacgatcgat cgcaactacg gacggctcct tcagcacaac gcccttaccc ttgatgtaca
    23581 caagaatgct ggcagtaccc aagtcgattc caatgtcagt cggcatcatc atcttctttt
    23641 tcctcctgtt tttttgccat ttatctatct aaaaacgata ttctggtttg taagcaaact
    23701 ataccactta ctattatata caacttcccc cgctttttaa agggtttttt ctttttttat
    23761 gatctttatt ctttttttat ggagccgtca cactttcttc acaattatac tctatactgt
    23821 aaccatgtta tccgaaagga tgacaggcct ttgtttcaag tattgcttga aataaaaaaa
    23881 gctttttcat actcataccg gacggtgaag agccgtccgg cccccctaag ccaatttctt
    23941 ttttatatat acctaccatt cccaatttaa caaacaaaac gcccgccggt ttttgagccg
    24001 acgggcgttt tgtttatatt tttttctgtc ctctacggtg cgcccgccgt ctcccccggc
    24061 agagctcccg ccaaaatatc ctggctgacc ttggtataga acatcttttt cacagtctcg
    24121 aagtctctgg tctgccccat aatccacatg agtttgacag ccgcggcctc caccgtcatg
    24181 tcgtaggcct gcaggacatt gtagctattg accgccttat agcccacctc ataaacctcg
    24241 gcgtcgcttc cctccagcat gacctgggtg gcaatcacca caattttccc ttttttcgtc
    24301 agattctcca gaccgctgag gaaattcctc ttattataga aaggaatgcc tcccacgccg
    24361 tagctttcga tgataatagc atcgtaccgc tctccgatgt actggagaat ctccggctcc
    24421 attcccggaa tcagcttcag cacaaacacg ctgggcttta aattttcgta aaaccgcaca
    24481 gttccgtctc tgctctcccc gtccacgtac tggataatcc tgttctcatc aataaaggcc
    24541 gctaccggat aattgatgct ctcaaaggcg ctgtagcttt tggagcggat tttcctggct
    24601 ctcgtcccca gaatcgcctt cccgtcaaag accaggtaaa ctcccctcac cccgtctcgg
    24661 gatgcaaagc gcagactgtc catgagattt ttcctggcgt ctgtgatggg aacgctgata
    24721 ggcttctggg aaccagtgag gataatgggc ttctccgaat tctgaatcag gtaggagagg
    24781 gccgccgccg agtaggccat ggtgtcggtt ccgtgagtaa tgacaaagcc gtcgaagcgg
    24841 ctgtactcct ctctaatctc ctggctgatg cggatccagt gctccggctg aacgttggtg
    24901 ctgtccaggc tgaacagctg cctcacagaa acctcacaaa atttcccggc ttccggaata
    24961 tagcttaaca gctcctccgc cgtggaggcg ggagccagtc cgttctccgt ctggacagag
    25021 gcgatggttc cccctgtggc tatcagcaag attcgtttca tacgatattt ccttcctcct
    25081 catcccagtt gtacagcggc cctatctgca gggagtatgc gctgtcttca ccaatataaa
    25141 tatctgcaaa aatgtaataa ttgtactctg gcttctccac atattccaga gaatccaggg
    25201 catctgaaag ctcgttctct gagagggttc cctcctgtcc cgccgccaaa tcggcaagcg
    25261 ccgtcatcat ctgcacagcc gcctggttgg aggcttcatt gtgggagttc acagcgataa
    25321 aatgaacctc ccctgtagcc gtatcgctgc tgattgtcac agccagctcc agctccttat
    25381 tctcatccca catggcataa gtccggtagg tatcatagaa ttccctgatc tcccctccct
    25441 catcataccg gttgttgtag gaatcaaggc tcatatgggg ttccaggccc agggcataag
    25501 cctcctcctt caccagattt tccacatcga tgaaacggat ctcaaaatga gtctctccat
    25561 tacatctgac tccagccgcc tttacttcct catcgtccag ctcctcccac tcaagagatc
    25621 ctgtatcctc ctcaatggtg atctccccgt cgtcccagac gtcctcttcc tgaatctcag
    25681 cttcccagtc ccagacgtcg ttctgcggtt cttcttcctg aaccagacgg gatcctccgc
    25741 ctctgtctgc catgaaatcg acactccagg aaataaactg tactgccact cccaaaataa
    25801 tgagaaacgc cgccacgatc ccaggcttca tcttgctccc tttcccgtct gcctttttag
    25861 cagatttctc ctgaagcggc tcattccata cagtctcctt tttaccggac gctttttggg
    25921 gcggcctgga ggtcttctgc ttctgcgccc ccctgccaga cttctgtttc atatcctggt
    25981 aaaaatctgc ggtcttttcc ctgaaatcct tctccgatac ctccagggct gtctggctgc
    26041 ggcctccgtt tctctcgttt aacgcagtct gctgccccgg cctggtctca ttcaggtaat
    26101 agtccacctc cctgatcagc ggcttaaata ccagttttct gcacagtctg cagtacccgg
    26161 atcctgtcag cggccgttca catatgggac aaattttttt ctgcataggc gcctcccctc
    26221 tattttgctg ccctccacag tcaggctctt aaggcagagc cgttttatac taaattctca
    26281 ggctccactc ccggcagtcc cacaccttcg tcaccacgtc gctgtaaaac tccggctcgt
    26341 ggcagatcag aagaatgctt cccctgtact ctttcagagc ccgtttcagc tcgtccttgg
    26401 catccacgtc caggtggttg gtcggctcat ccagaagcag aagattcgtc tccctgttaa
    26461 tcagcttgca cagccgcacc ttggcctgct ctcctccgga cagcacccga acctggcttt
    26521 cgatgtgctt cgtagtcagt ccgcacttgg ccagggcaga gcggacctgg tactgggtat
    26581 aggatgggaa ttccttccag atctcctcga tacaggtggt ggtattgccg ggagccatct
    26641 cctgctcaaa gtatccgatt tccaggtaat ctcccagcac cgccttgcca gacaaggccg
    26701 gaatcagccc cagaatactc tttaaaagag tagtttttcc aattccattg gctcccacca
    26761 aagcaatctt ctccccccgc tccatgtaaa ggttcagggg cttggacagg ggctcattct
    26821 ggtcatagcc gataaccaga tcctctgtct cgaaaataca ctttccagcc gctctggcct
    26881 ccaggaaatg aaactccggc ttcggcttct ccttagccag ctcaatcaca tccatcttgt
    26941 ccagcttctt ctggcgggac atggccatat ttctggtgga aactctggcc ttatttctgg
    27001 ccacgaaatc ctgaagctcc gcaatctcct gctgctgtct cttgtaggcc gcctccagct
    27061 gggccttctt cacctcgtag acctcccgga acttgtcgta atctcccaca taccggtcaa
    27121 gtctctgatt ctccatgtgg tagataatgt tgattacgct gtttaagaag ggaatatcat
    27181 gggaaatgag gataaacgca ttttcatatt cctgcagata ccgcttcagc cattcgatat
    27241 gctgctcgtc caggtaattg gtaggctcgt ccaaaagcaa aatatccggc ttctcaagca
    27301 gcagctttcc aagcagcacc ttggttctct ggccgccgga cagctctgtc acatccttct
    27361 ccattccgat gtcagccagg cccagagccc gtcctacctc gtctaccttg gcgtcaatgg
    27421 tatagaaatc gtgaaccatt aaaagatcct ggatcgttcc aagctcctcc atcatagatt
    27481 ccatttcccc ttccggcgct tcccccagac ggtcgcagat gccgttcatc tgctcttcca
    27541 gctcgaacag gaaggaaaaa gcgttcttta agacttcccg gactgtcatc cccttctcca
    27601 gcacagcgtg ctgatccagg tatcctacgc ggactctctt agcccactct accctgccct
    27661 cgtccggctg cagttttcct gtaataatat tcataaaggt agattttccc tctccgttgg
    27721 ctccgatgag accgatgtgc tcccccttta gcagacggaa ggacacatcg tgaaaaatcg
    27781 ccctgtctcc aaatccatgg cttaaatgtt ctacgtttaa aatactcacg gttgtactcc
    27841 tttatctttc atgctcagcg tccatataca gctttatttt acctgaaccg cccgtttctg
    27901 tctagccaag acgcccttta aagtcctcgt acccgaactc ttttatcaaa atttcttccc
    27961 cgtctctgtt cttccataca atggaaggca gaagcatgcc gttgaaggta ttagtcttta
    28021 ccatggtgta gagagccatg tcgccgaaca ctacctgttc tccctctgcc agcggatggt
    28081 caaaggaata atctccaatc acgtctccgg ccagacaggt ggggccggcc aggcgatagg
    28141 tgtactcctt ctcaccaggc attccggagg aaagcaccgg cggacggtag ggcatttcca
    28201 gcacgtccgg catgtggcag gccgcggagg tatctaaaat ggcgatattc atgccatttt
    28261 tcatggtttc cagcacagag gacacgagaa agcctgcgtt cagaaccacc gcctcccccg
    28321 gctccagata gacctccaca tcgtactgtt cccggaaatg gcgaatgacc cgctttaacc
    28381 gctccacatc gtagtcttcc ctggtaatgt ggtgtccgcc tccgaaattg acccacttca
    28441 tctgtcccag atacctgccg aacttctcct caaaggcctg ggctgttgtc tccagatcat
    28501 cggaattctg ctcgcagagc gtgtgaaaat gaaggccgtc caggagagga agaagctcct
    28561 cgtcaaactg ctccttcacc gttcccagac gggatcccgg agcgcagggg tcgtagatag
    28621 cgtgcccctc ctgggtggaa cactccggat tcacccgcag tcccacagat tttcccgcct
    28681 gcttcgccct ccctgcgtgc cgcctcagct gcgccgggga attgaacaca aaatgatctg
    28741 cgtaagataa aagctcctca aactcatcct cccggtaggc cggggagaac acatgggtct
    28801 ctcctccgaa ctcctccttt ccaagccttg cctcgcagag gccgctggcg gtggttccgg
    28861 ccaggtaccg gcgcatcagc ggataggcga aaaagccgga aaacgctttc tgggccagca
    28921 ggatcctgca gtcagtctcc tcctggatct cctttaaaag ctccaggttt tttaccagtc
    28981 tttcctcgtc aaccagaaaa tatggggtct taacagccgt ctctctcttc atctgtctgt
    29041 ctcctttatc tgtctcctct atcacataaa gctgcgtcct ttgcagaagg aagctctggc
    29101 tcctctgaaa aaacgcagct tttcttcagt ctctatttca acgtcaactg gcagtcctta
    29161 taaacagatt agtctacaag caccagatcg tgggactctc tccacggaag tccccactta
    29221 tttaaggcgt ccataaatgg atccggatcg aactcctcca tgttgtaaac gcctggcttc
    29281 tgccatttgc ctgtcattac catcatggcg ccgatcatgg ccggaacgcc tgtggtgtag
    29341 gcaactgcct gagatcctac ctccttgtag cactcctggt gatcacagat attgtacagg
    29401 tagtaggtct tgtcctttcc gtccttcttt ccgcggaaaa tgcagccgat attggtcttt
    29461 ccctttgttc tcgggcccag ggaagacgga tccggaagaa ctgcctttaa gaactggagc
    29521 ggaataatct ccttgccctc gtacatgatc ggctcgatgg aggtcattcc cacgttctcg
    29581 agacatttta agtgtgtcag gtagctctgg ccgaaggtca tgaagaagcg gattctcttg
    29641 attccaggga tatttaaggc caggctctcg atctcctcgt ggtgaagcag gtacatatcc
    29701 ttctcgccta cctcctcgaa gttgtacacg cgcttgatct ccataggctc tgtctctacc
    29761 cagtggccgt cctcccagta ggagccctta gcggacacct cgcggatatt gatctccggg
    29821 ttaaagttgg tggcgaatgg gtatccgtgg tcgccgccgt tgcagtctaa gatatcaatg
    29881 taattgatct cgtcaaactc gtgctttaac gcgtaagcgg agaatacgct tgtcacgcct
    29941 ggatcgaagc cgcttcctaa taaagctgtg attccggcct gctcaaactt ctctctatag
    30001 gcccactgcc agctgtactc aaacttggcc gtatcctccg gctcgtagtt ggcagtgtcc
    30061 acatagtgag tctttgtagc caggcaggca tccataatgg tcagatcctg gtatggaaga
    30121 gccaggttca gtactacgtc cggctttacc tcgttaatca gggcaattaa ggcgtccacg
    30181 tcgttggcgt ccacctgagc cgttgtgatc tttgtggaag tagttctctg aagcttctct
    30241 ttcaatgcat cgcactttga ttttgtgcgg ctggcaatac agatctcctc aaatactccg
    30301 ctgttctggc agcacttgtg aactgctacg gaagcgactc cgccgcatcc gataatcaat
    30361 gcttttccca tgatcattct ctccttttcc tgtttgattt tctattatct ctttatctgt
    30421 gtttttcctg gtcctgcctc tgaagggcca gggccatttc cctgacaatc ttgcaggcgg
    30481 ccgctgtgga cgcgccgctt aaatcgtagt gggggcttaa ttcattcaca tcgcagccta
    30541 cgatattggc cctgtcgcac accagtgtga cggcccgcct cagctggtca aaggtgacgc
    30601 cgcccggctc cggagttccc gtccccggaa atacggaagg atccatcacg tccagatcca
    30661 ctgtaaagta aacaggacgg cccctcagcc gttctaacgt ctcctcaagc cctgtgaaat
    30721 caaagggatt taagaacgtg tgctcctttg cccactgaaa ttcccatctc tcaccggagc
    30781 ggattccaaa ctggaaaatg cttccgtctc ccgtcagatc ccagcagcgc cggatgacgc
    30841 aggcgtggga caggggctct cccagatagt cctctctgag atccgtatgg gcatcgaaat
    30901 ggataatcgc cgcatccggg tactttttgt gtacagcccg aaagctccca agtgtcacca
    30961 gatgctctcc tcccagcata aaggggcgtt tgcctgcctc taaaataaac gctgtccgtt
    31021 cctcaatatc tgccagcgcc tgcttcggat ctccgaaccg aagctccaga tctccgctgt
    31081 ccataataaa gctgtcctcc agatctcgat cctggtaagg gctgtaggtc tcaagaccat
    31141 aggattcccg ccggatggcc tcgcttccga acctggttcc tggacggaac gaggtggtag
    31201 aatcgaaggg cgcaccgaac agaaccgtat ccgcctcctc aaactccgcg tcaaatccca
    31261 tatatacgga aacattcggg gacagcgtcc ctgcctgtct cttttcctct gacatactgt
    31321 atctcctctc ttctccctct gtctgcgccg cataccgcgg cctcttttat cccgagctgc
    31381 gcttctgccg cggcccgcct ctgctctctc agatttctac tctacctctt ctaacatctg
    31441 ctctacatag gccggcagat agaaggctcc cttgtgaaga gtggtggtat agtaattgca
    31501 ggaaaggcct ttcagattcc aggcagcctc cctcagatcc ttcagcggat ggtatttctt
    31561 ggaggcgaag ccgaacagcc agtggccgga cgggtaggta ggaatgtgag cctggtatac
    31621 gcggctgatg gggaaagatt ccacaatccg cttgtgggct ctctggcagg ccaccgcgtc
    31681 ggccggatag aaggggctct cgtgctggtt caccataatt ccgtcctcgt ggagagcctt
    31741 aaagcagctg ccgtaaaact ccctggtgaa cagtccctct cccggtccga agggatcggt
    31801 ggaatccacg ataattaaat cgtacttgtc ctcacaggaa cggacaaaac ggacgccgtc
    31861 ctcatagtgg atgctcagcc tcggatcgtc caggcggcag gaggtcttcg gcagatattt
    31921 tttgcacacc tccactacca gctcgtcgat ctccaccaga tcaatgtgct caatctccgg
    31981 gtatctcgtc agctcccgga tcacgcctcc gtccccggct ccgatgacca gcacgttctt
    32041 cactgccggg tgcaccgcca tggggacatg ggtgatcatc tcatggtaga taaactcatc
    32101 cttttccgtc agcatcatat atccgtccag cgtcagaaaa cgcccgaatt ccggggaatc
    32161 gaacacatca atgcgctgaa actcgctttt tccgctgtaa agctggcgat ccacacgaat
    32221 ggacagcttc acattgggag tctgttcctc tgaaaaccag tattccatcc tgttctcctc
    32281 tcttctgctt cttttcttct gcttctttta tttcccttaa ctttttaatt gcttcccttg
    32341 ataacgttca gccgcagaat gtccgcgtcc tccggtcctg tcatggtaca tcccttttcc
    32401 ttggcaaagg caatgtatgc cagaatttcc tctgtaatcc gctcgccggg cgccagaatc
    32461 ggaatgcccg gcggatagca catgacaaac tcgctgcaga tgtatccggc tgtctcctcg
    32521 ataggcaggg atatcttgtc tgcgtaaaaa gcgtcctgag gcgacacggc cacctgggga
    32581 tcaatgtact ccggcaccgc catacctgtg ccggttgtgc cgaatctgcg ccggatctcc
    32641 gccagggcgc tgacaaggcg ttcaatatcc cgctgtctgt cgccgatgga aaggtaggcc
    32701 aggagatttc ccagatctcc aaattcgatc tgaatatcgt attcgtcgcg aaggagatca
    32761 tagacctcga tgcctgccag accgatgtcc agcgtatgga cagagagctt cgtcacatcg
    32821 aaatcgtaaa tgctgtcccc gttgatcagc tccttggaaa aggcgtagta gcctccaatg
    32881 gcattgatct cttttctggc gtcgtcggcc atccgcacta cccctgcgaa ggcttccttt
    32941 cccctgagag ccaggttccg tctggaaatg tcaaggcttg agaggagcag ataggatccg
    33001 ctggtggtct gtgtcaggtt gataatctgg cgcacatggc cctcgttcat ggccggcccg
    33061 attaagagca gtgagctctg cgtcaggctg ccgccggatt tgtgcatgga aacggcggcc
    33121 atatccgctc ctgccgccat ggcggacacc ggcagatttt ctccgaagta gaaatgcgtt
    33181 ccatgggcct cgtctgccag gcacagcata ccgtggctgt gggccagccg gacaatttcc
    33241 cgcagattgg agcagatgcc atagtaggtc gggttgttca ccagaaccgc cttggcgtcc
    33301 ggattctcct taatcgcctt ctccacctgc tccaccttca tgcccagcgg aatccccagg
    33361 cgcatatcgc actctgggtt tacataaaca ggaaccgctc cgcacaaaat cagcgctccc
    33421 accacgcttc tgtggacgtt tctgggcaga ataatcttat ctccccgctt taccacggaa
    33481 aggatcatgc tctgtaccgc agaggtagtt cctcccacca tcagaaacgc gtgggccgct
    33541 ccgaacgcct cagccgccag ccgctccgcc tctgcgatca cagagactgg atggcacagg
    33601 ttgtcaaggg gcttcatgga attaacgtca attcccacgc acttctcccc caacaggttt
    33661 actaattctg gatttcccct tccccgtttg tgtcccggca cgtcaaaggg gacaactctc
    33721 atatgtttaa aacgctccag cgcctcgaaa atcggggcgt tatcctgagt cagctctctc
    33781 accttccagc tctcctctct tgattttttc tgtatccgtc cagagcctaa agccctggat
    33841 ggtaaatatt tcttccgctg aagatctcaa tcatctcacg gcgcaggctg tgcataatct
    33901 ccaggcgcac ggtgggcgga agctcgtaaa tatctgtctt aaacaggtaa ttctgtaaat
    33961 ccacctcttt gaccatcatc ttggtgtgga acagattcgc ctcgtatacg ttaatatcta
    34021 ccgcatcgta gcggcgcatg atttccgggt caatgtaatc ctgaatagag gccacatggt
    34081 gatccataaa cagcttccgc ccgtccacat ccctggtaaa gcctctgacc cggtaatcca
    34141 tggtaataat atcggaatca aaggaacgga tcaggtagtc taacgtggag agcggcgtga
    34201 tctcgccgca ggtggccaca tcaatgtcca cccggaaggt ggccagacag gtctctggat
    34261 gatactccgg atacgtatgc accgtaacgt ggctcttatc cagatgagcc agctgcatat
    34321 ctccggccgg aaccatggtt ttctctgcaa tcaggatcgt cacggaggct ccctggggct
    34381 cgtaatcctg cttggcgata tttaatactc tggccccgat catgtctgtc agactggtaa
    34441 ggatgttcgt cagacgctcg gaattgtact gttcatcaat gtaagcgata tagtctttct
    34501 gttctctggc tgtcttcgcg taacagacat cataaatgtt aaagctcagg gacttcgtca
    34561 ggttgttaaa cccgtacagt ttcatctttt cccccatgat tttctccttt gcccaaatgt
    34621 tctaaatatg gtaaatagga atgtgtctat gcagagcatt ttttatttca taggacgcag
    34681 tttcctgtga aatcccatga aataaaaaag ggactgtgcg cccgctgcac acaatccctg
    34741 cgtctattcc atctctgata tattctctgc agtccaaaga ctcccctccg gcagcttttc
    34801 cccgcgctct ctttcgattc aggtctgcgc ctctctgccg cgccgcttcc cggcggcttt
    34861 cccggtctct tctgcaaaaa ttgtatcgta cccggagtcc ccttccccgc tgggattctc
    34921 cgcgtctttc catagaatgt aaagtccaga gtctatatag caaatatctc acttttacta
    34981 ctcttattga ccgtttcaca agtggttgca cgcagaacgc gtactggtta taaagtaacc
    35041 aacttataaa atttgagctt ctaactcaat caataaggca acaaaatgtt accagaccgg
    35101 cacttgcccc ggctgtccgt atggccttga ctcctgtcgg agtgggcaat aatatttgca
    35161 tggaagttct tcttctgctt tcatcccatg acgggttaac tatatcgaat ttcagtgctg
    35221 ttgtcaatcg ttttttcagc gttttcttcc ctatctgcta agcgccatgg acagaagctc
    35281 ctcccggctg tttttctgcg gatcctccag aacttctgca aacagccccg ccagcgtttc
    35341 gcctaccgtt ttccccggtt ttacacctgc ttccatcaaa tcgtttcctg tcaccttcat
    35401 atctttcatc cgcacgcagt ctccccgctc ccggatccgg cggcacagct tttctgcctg
    35461 ttctgcctgc tctctctttt ccggaagcag gtttctctca aagattaaaa aggcgtcaaa
    35521 cagccagtct tccatctggc tcattgtcct tctcaccgcc ccttcctctg tcggaagagg
    35581 aagtccggaa aaggcggcca gcgtcttcgc gctgcggatg gtatgattgt ccagcttcag
    35641 ctccctgaga atggtctccg tcttcttttc tcccagatgg gccagcagcg ccccgtatct
    35701 gaaatacttc tccgccggaa gctcagcgct tcttctgagg cgttcctcta gatagattcc
    35761 aaggctttgg gcctctgaaa aaatgtccgg aaagctctgc gtcatatagg ggctcatccc
    35821 cgtcttctcc atggccagca cgccctgagg attgccggaa agaagcgtct tcgtaagctc
    35881 cgtctgaatc cgttccttgc tcacatggga cagattcggc gcaatggcag agagcgcccg
    35941 ccaggtttcc tcctcaatgg taaaattcag ctgggcggca aagcggaccg ctctcataat
    36001 ccgcagcgcg tcctcggtaa aacgctccat ggcgtttccc acacagcgga tcctccctgc
    36061 ctttaaatct tccagtcccc cgaaaatatc caccagcccc gtctcatggc tgtaggccat
    36121 ggcgttgatg gtaaaatcac ggcggtgcag atcctcccgc agatctgccg taaattccac
    36181 ctccttcgga tggcgtccgt cctcatactc cccgtcaatc cggtaggtgg taatctcata
    36241 gcccacgtga tcccgtatca ccgtaaccgt cccgtgctga agcccggtgt ccaccgtttt
    36301 tccaaatacg gccttcacct gctccggccg ggccgaggtg gtaatatccc agtctccggg
    36361 ctttctgttt aagatggtat cccgcacgca gccgcccacg gcaaaggcct cgtagcctct
    36421 gtcccgcagc tttttcaaaa tccactccac ctgagacggc agctcgatca caaagtcttc
    36481 cttattattg acaggataat ctcggttcat gtgttccttc tctttctaaa ctcgtttttc
    36541 cataatatag ttggtgagca gcacgccctt tcgctccacc tgctgctctc tctgcacctg
    36601 atagccccgg gcctcaaaaa aaggtctggc tgtaatagaa gcgtgggtgg tgatgcagac
    36661 ggaagcgtct ggctttgtct gtctcaccgc tctgaccgcc tcctgctcca gcgcctggca
    36721 gagagccgtc ccgacaccca ttccctgaaa atccctgtgg acgtacagcc ggtccagata
    36781 tcccgtttcg tctatgtcgc caaagcctgc cagaatcccg tctgcctccg ccgccaggct
    36841 gaagtgggcg cagagcgatt cgttccattt ggccgcatcc ggttttccgt ccgcccaggc
    36901 gtccagctgc tcttctgtgt aatccctggc attgaccgta tgcacggtgt cgtaaaacag
    36961 gcggaggact tcactgcagt cggaagggcg gtatgctcta agaaccacag aaatcgggct
    37021 gcgggaaggg actttcctat ctatttcctt ctgcatgtgc ttttcatgtt tcatgtgatt
    37081 gttccatccc tctgtttcat tatccttatt ctgcttcgca gacgcctgct tttctcccgc
    37141 tgcttcgcgg acggctgtct tttttcagca tatcgtgaac gcagcccgct cagtcatttc
    37201 gccgttcgcc aaacatgcag gcacgttttt ctcacttacg ctcattatat cacagacatg
    37261 cggctggaac caccgaaaaa tcgcagagcg ggcttctctg aaaaacgccg caaagcggca
    37321 gattcccctg ctgccctgcg gcgtttcttc tttttattat gattcttatt gttcttcgtg
    37381 tacaggctgc acttcgctgt ctgattatat cagattagta cgccttgccc cagtaaacca
    37441 tctttgcagc cggctttccg cagcagacac aggtatcggc taccttctcc tgcttaaacg
    37501 gcatacatct ggaggttacg cctgcaatct cctttaactt gtcctcgcac tcctggcagc
    37561 cgcaccacat tgcacggata aagccaggct tattatctgc cagatctttc atctcatcca
    37621 ggttcacagc cgtgtaggta tgggcgtcgc ggtgagctct ggcgcgctca aacatgtcat
    37681 gctgaatcgt gtcgagaagc tctgttacct tctccttgat ctcgtctaag gataccgtca
    37741 tcttctcatg agtatcgcgg cggactaata cggcctggtt gttctccaga tcctttggtc
    37801 caatctccac gcgcacagga attcctctca tctcagactc gctgaacttc cagcccgggc
    37861 tcttatcaga gtcgtctacc tttacgctga agccggaaag cacgtccttt aactggtatg
    37921 ccttgtccag aacgccctct gcctgctggc ggatcggaac aatcactacc tgggtcggag
    37981 caattctggg aggcagcacg agaccgttgt catcgccgtg aaccatgata atggctccga
    38041 tcagacgggt tgtcataccc caggatgtct gatgaacata ttttaacttg ttgtccttgt
    38101 cggaaaactg gattccaaag gccttggcga agccgtcgcc gaagttgtgg ctggttccgg
    38161 actggagagc ctttccgtcg tgcatcaggg cctcgatggt gtaggtagcc tcagctcctg
    38221 cgaacttctc cttgtctgtc tttcttccgc ggacaaccgg catggccagc acttcctcgc
    38281 agaaatcagc gtagagattc agcatctgct ctgttctctc ctctgcctcc tccgctgtgg
    38341 cgtgagcagt gtgtccctcc tgccataaga actctctgga gcgcaggaac ggtctggttg
    38401 tcttctccca acggacgaca gagcaccact gattgtagag cttcggcaga tctctgtagg
    38461 actggatatc ttttgcatag aaatcgcaga aaagcgtctc agaggtagga cgcacgcaca
    38521 ttctctcctg aaggggctcc agtcctccgt gagtaaccca ggctacctcc ggagcaaagc
    38581 cctccacatg atccttctcc ttctgaagca ggctctccgg gataaacata ggcatgtata
    38641 cgttctgaac gcctgtctcc ttgaaacgtc tgtctaactc cctctgaata ttttcccaaa
    38701 ttgcgtatcc ggccggcttg ataaccatgc agccctttac gctggagtaa tcgattaact
    38761 ctgccttctt taccacgtct gtgtaccact gagcgaagtc cacatccatg gaagtaatgg
    38821 cttctactaa ttttttgtcc tttgccatgg caattctcct tttccctttt aaaatattga
    38881 ataaactgca cgaaagaatt ctgctctgca gaattctccg cctgcggcgg gctgctcagc
    38941 agcataatac cgcaccgccg cagcgcggtt cctgcacagc atttatctca caaggcgcaa
    39001 tgttctgtga aataaaaaaa ctgcccaatc cccactgaac atagggaccg aacagtctgc
    39061 actatcggcg gtaccaccct gattaaccgg acacgccgat tctctctcgc tccgttaacg
    39121 ccggaatacg ttgcactttc gcagaggaaa ctttacatca atcatccgct tcgtctcccg
    39181 ccgcctcatg cacagctccg aggaaggttc aatcctgagt gacacaggga cgtcccacca
    39241 tccgccccct ctctggaagt gtgtcagaat ctactgggcc tcttcacagc catttatcta
    39301 ctgctgattt tacgctgtgg ccggtacttt gtcaagagcc tagttcttct agtttccggt
    39361 tgataaaaac ggaaatgtgt agtattatct atacatctta caaaaaaact caagattttc
    39421 cgaaatcttg agtttcaatt cgtattggag gaatctcgct atggatttga cttgctacaa
    39481 ctcctactat gaagtgaatc tgtccgttct ggaggaaaac ttcaaaaaaa tctcccgctt
    39541 tatcgccccg gcccaggtca tcccggttct gaaagcggac gcctacggca tgggcgctct
    39601 ggaaatcgcc agagtcctga cagagcgctg cggctgcaga actctggcct gttcccagac
    39661 ctacgagggc ctggttctgc gggaaggcgg cattaccgac gcggaaattc tgatcatggg
    39721 gccagtgctc cacgataccc ttccccacgc cgtccgctgg gatatgcaga tcccgctgtt
    39781 caccccggag cgggtgcgtt ccctctccag agaggccgcc agacagggca aaaccgtgaa
    39841 agcccagatt aaaatcgaaa cggggctgaa ccggatcgga gcctggcctg gaaagcagct
    39901 tcaggaggtc atcgacgccc ttcaccagtg ccccaacatt caggtagtag gcgcgttcac
    39961 ccatttcgcc caggcggaga cgccggaaga cgccttcaca aaagaacagt tcgccgtgtt
    40021 caaagaggga gtcgcccagc ttgaagaagc cggatttcat ctgtcctata tccactgctg
    40081 caatacggga gcctccgagt ggtaccggga agcgctggac ttttccaccc acatccgggc
    40141 tggcagcctg gtgttaggct acagcgatat cgccgacgga tccaatccca tggggcttcg
    40201 ggaaatgctg tcctggcgga cgaccgtcag ctttatccgc cacgtggagc ccggcgagac
    40261 agtcagctat gaccggcttt tcaaggcgga aaagcccacc gacatagcgg tcgtatccgt
    40321 aggctttgcc gacggcattc tgtgcgccat ggcccgcagc cacggcccgg ttctcgtcaa
    40381 cgaccagcgc gcccactacg tcgacacctg tatggatcag tgctttgtgg atgtgacggg
    40441 gcttgactgc agggtggggg atccggtaac actctggggg tattctccca gcggcagggc
    40501 ctttctgtcg cctcaggagc tgtctaaata cggccaggtg tataccgcct acacctctca
    40561 gaggccgaat cggattggac gaatctacat cggataggga aagcagagct tgtccatgcc
    40621 ttcgtccttt gtcatagcgg ccgtcggttc aggcggaaaa accacggcct taaaagagct
    40681 ggcccgccag gccgctctcc gaaaccagaa cggctctgtc ctcttagccg cgtccaccca
    40741 catgtacccg gttcttcccc cggaaagccg ggtttttctc agggatccag acgaaaaaac
    40801 tctgcgccgt gagctggctg agcctggaat tgtctgtgcc ggacggactg cccgggatca
    40861 aaaaatctcc gccctggaac cagagctgtt ctctgccgcc ctgcagaccg cttcggtcat
    40921 tctctgcgag gcggacggat ccaggcgtct ccctctgaag cttcacagcg aacgggagcc
    40981 tgtccttcct gcccggacag acgtctgtct cataacagcc gggctttccg cgctgggaaa
    41041 ggaggcaggt tcctgtatcc accggtacga gctgaatcct gtctggaaat cccgcccgga
    41101 taccagaatc ggcggggagg agctggccct ctgcgttctc gacgccgtat cttctgtcat
    41161 gcttcccacg gagcaggacg gcagactctg cgctccaaaa agccgcggct tcggcgtccg
    41221 cctttctaaa aagaggattc ggattctcct gaaccaggac gactgtctgt tctgccctga
    41281 aagcaatggt tcctctctgg cggccctccg gaaagaagcc tccgctgccg tccgtatgtt
    41341 agaggaacac ggtctttcct gccggatggg aagcctttta gaggacagtt cctttctgtg
    41401 ggactggatc gtctcctctg gccgctagaa gaggcggatc tgtctgctgg cggcaagtcc
    41461 cagcaatgcc tccagcactc ctccggccac ggcgttcgct ttatcggata ctgtgccgca
    41521 gaatgccgcc tgctccgggc gagggtcgat atctgcgatt ttaagccctt ttttcacagg
    41581 aaagccttcc tggatcaggc ctcttaacac gccgtccagg gaagccttta ccggagtccc
    41641 ctctatcatg gcaatggtct gtcctttctt taccatcgcc cctatctcta ccatgtttcc
    41701 gctctcatct ttcacaaagg aaaggcggcc ctcctcgggg gcatgaatca cccgttcagc
    41761 gccaaatccc tggatctttc ccggaattcc tgtattggga atggcctgtc cctcccagat
    41821 aacacgtccc agaaaatgtc cccgcatggt ttccaccacc gcgtccacat cctgtccggc
    41881 agtaaagccg ggccccgctc caatggtgat gggagccatc gaacggctgg tccccagatt
    41941 gcgctttgcc agaattacgt cgatcaccgc ggctgggtga agcttatgga cacaggcggc
    42001 agtttcgtca atcagaagcg ggatttgtcc ctgagcccag attttctccg cctgttccgg
    42061 cgtttgggcc agcctgcagc ttacgccttc cacctgggtt tcccccgtcc acacggcctc
    42121 acagaaggag gcgcggcggc ggatggccga cgggtttttg cactccaggg cagccacccg
    42181 aaaaccgctg cggtaaaggc ggagaatcac ccccgtagcc agatctccgg ctcctctcac
    42241 cagaatccag gggcctgcct caaaaaattt cgtgttttct gtgtttttta tatattcagg
    42301 gaaatacttt cctgccagag tgtccagccg gaccgccgcc tcccgctcaa aggcccggta
    42361 gcgtttcagg aggctttctg cctccccggt cagatccgct ccccctccac cttttcctcc
    42421 gatttttttg tttaaaaggg aaattccaag ctccctttca cagttcttaa tcatggtcca
    42481 tgccttgctg tagctcatat ccatatcagc cgcgcttttt ctcagagagc caagccgggc
    42541 cacgccctcc agcagactgg cgattccagg cccaaaggcc ttctgatcgc ccttcaggcg
    42601 gatcgacgac tgaacgttca gctgtttttt cactgttctt tcctcctccc tctctggctg
    42661 cttctatttt tcccgttttc actcaggcct ttcatcattt cctttaactc ttctgcatat
    42721 ttatgggaaa ccatcgttgg gttagcgcgc agggcagact gcagaaactg ttttctcctg
    42781 tccctgattg ccaaaagagc ctcttccctc tccttcagcc agctctccag ctccgcgcgt
    42841 ttctcttcga ttctgtcccc ggcatccatt tttaacaaag cagtctgaac tctgagccca
    42901 tccagctcct ggcgaatctg attcgcccgt tccagagaat gtccaaaatc caaagcttcc
    42961 ctgatacttg caaaggcgtc ctgaagaaaa actgcagtaa ccggcagtat caaaagtaaa
    43021 tccaaaataa ccggtattcc gcagacaagc ttctcaatgg gcctgtgtat caaatctgtc
    43081 ataaaaattg tcaaaaaacc ccaggcaaca gacgaactaa gacagatata gccgtgaaaa
    43141 ttaaatctct ggctgctgta atcccagtag cgtaccttaa acagctgctc catggcccat
    43201 cctgccccat attctaacac cgtagctccg gtaaagccag acagccatgt caaaagcaga
    43261 ctgtcctgaa acggtctgga aacaatcagc atcataagcg ctccgcttcc ataaagaggg
    43321 agcaggggaa tccttaaaaa gcctctgttt accagccttc tctgctttac tgaaacatac
    43381 gacgattcaa aaatccagcc taaaaaacta taaaaataaa aaaaagtaag ccattgatac
    43441 catgtataca aatccatctg ccgcctccaa ttcagtctcc ccatttcatt cgttttattt
    43501 ttatggccag tatatcacag cgcgctgcct ttgactatct caagatcatc tgcctggcgt
    43561 cagacgaagg aatgccgaag cttttctttc gccgctgcga aaccggcagg gattcgttca
    43621 ttttccaaaa aaataacgac tgtccggcgc cggctttcta tgctataata gcggcatatc
    43681 ttttattttc aggaggctgc catatgaagc ttatgcggac ggaggatgcg gcagggcagg
    43741 tgctctgcca cgacattacg cagattatca agggcgtcac caaggacgcc gtattccgga
    43801 aggggcatat catccagccg gaggatattc cggtgctgtt aagcgtcgga aaggaacaca
    43861 tctacatctg ggaaaacgac gagaccatgc ttcacgaaaa tgaggcggcc gggattctct
    43921 gccagctctg ccagggacct ggcatgaggg cctctgagcc taaggagggg aaaatcgagc
    43981 tgactgccaa gcacgacggt ctctttctgg ctgatgtgga gcggctgcgc cggatcaatt
    44041 ctttaggcga aatgatgatc gcctccagac ctggaggctt tccggtcaaa gcaggcgatc
    44101 gtctctgcgg cacacgggtg atcccccttg tcataaaaaa agaagcgatg gagcgggcca
    44161 gacaggccgc aggcccaaag cccctgttct ccctgcttcc ctttaagaaa aaaagcttcg
    44221 gcgtggtgac tacgggaagc gaaatctttc acggacggat tcaggatacc tttacgcctg
    44281 taatcgaaga aaagctggcc gagtacggct gcgccatgga ggcccacgaa atctgcgatg
    44341 acagggaaga ggagattata aaagcgatcc aaacgatggc tgacaggggc attgacatga
    44401 ttttctgcac aggaggcatg agcgtggatc cggacgacag aacgccttcc gccatccgga
    44461 aatccggcgc gtccattgta agctacggcg cgcccgttct cccaggcgcc atgttcttag
    44521 tctcctacct gccggacgga cggcctgtct gcggccttcc gggctgcgtc atgtacgcca
    44581 gacggacgat ttttgacctg gttctgccca ggcttcttgc agacgtgccg gtgacttccc
    44641 agtggctggc cgggctgggc cacggagggc tctgcctatc ctgcccggaa tgccatttcc
    44701 ctaactgcgg ctttggaaag ggcgtctgat tttcagcccc atgccggcgc tgcagctgtc
    44761 agtttcaaaa ccataacacg attcacaatc acaaggagat aaaccatgaa ttttacacac
    44821 attgatcacc agggcaacgc cgtgatggtg gacgtcagcc agaaggcctt taccgcgcgt
    44881 accgcctctg cctgcggccg catccgcatg agccgggaat gctaccaggc cgtggagtcc
    44941 gggaccgcca aaaagggcga cgtgctgggc gcggcgcaga ttgccgggat catgggcgca
    45001 aagcagaccg ccgatctgat tcccctctgc caccgcctga acctgtcaaa agcctccgtc
    45061 tcattccgcc tgcttccaga gcttccaggt gtggaagccg tctgcaccgt caagtgtacc
    45121 ggccagacgg gagtggagat ggaagctctg actggagtga atatcgcgct tctcaccatt
    45181 tacgacatgt gcaaggccat agataaacgg atggtcatga aggatatcca tctggtggaa
    45241 aagcacggcg gaaaaagcgg agatttttcc tttgacggcg aacgaaaaga cggcgcggcg
    45301 gaggcctcct atgtgtaatt ccatatgcgg ttccctccgc gattcctatg gaagaaccat
    45361 cgactatctg cggatttcta ttaccgatca gtgcaattta aggtgccgct actgcatgcc
    45421 tgggcaggat ggcatttctt ccccctgccg gctgatgacc ttcggcgaaa ttctggccgc
    45481 agccagagcg gccgcccggc tgggaatacg gtctgttaaa attacgggcg gagaacctct
    45541 gtgtcggcca ggctgtccgg atctgattgg acgtcttaag gaaattcccg gtatccggca
    45601 ggttaccatg accaccaacg gactgctggt ttccaggtat ctggacgaac tgctgaacgc
    45661 gggcctggac ggaatcaata taagcctgga tacccttaac gaggagcagt ttcgccagat
    45721 tacaaggcgg aattttcctc tcagccaggt attggaggct ataaaacggt gttctgaaaa
    45781 gcttcccaca aaaatcaacg cagttttgct cccagagaca gaggaccagc tgattcctct
    45841 ggcccggctg gcctgcttcc tgcctgtaag cgtgcgcttt atcgagcaga tgcctctggg
    45901 gggagaacgg ccgtccaaag cttcccgggg ctgggattcc gtgctggccc gcctgaaaaa
    45961 agagtggccg gatctctccc ccgtaccgga gcgcagagga aacggccccg ccgtctacta
    46021 cagcgccccg gaattttcag aagctgtggg gctgatcgaa gcagtcagcc attccttctg
    46081 ctccggctgc aaccggatcc ggctcacctg cgaaggccag ctgaagccct gtctctgcta
    46141 cggagacagc ctggatctga cgccagctct gaaatccaaa aatgaggaag agctgctggc
    46201 cctgtttctg aaggctgtca gaaataaacc gaaggcccac tgctttcggg aggcctctga
    46261 ggtcagcgaa cgccgataca tgagccaaat cggcggataa cactacaaaa tctcttggaa
    46321 aacgattgga ggaatatcta tgggaacggt actggccgtg tgcagaagct ccgtccgggg
    46381 cattcaaaaa acaaacgaac agagcggatg gtttgaaaca gaatggggaa tccggggcga
    46441 tgcccacgcg ggccggtggc accgtcaggt gagcctttta agcgcggatc ggatcgcccg
    46501 ttttaatgaa aaaggagccg gagtcggccc cggcgatttc ggtgaaaacc tggtggtgga
    46561 gggcattgat ttttcctccc tgccagtggg aacctggctg cgctgcgggg acgtgctgtt
    46621 ggaaatcacg cagattggaa aggaatgcca cagccactgc gccatctacc acaaaatggg
    46681 cgactgcatt atgcccagag agggagtttt cgcccgggtg ctggaagcag ggcagatctc
    46741 gataggcgac cagatgtccg tggttcccag aaaggagccc cttcccttcc aggctgccgt
    46801 cattaccctt tcggatcgct gttcatccgg agaacgggag gacgaaagcg gcccggctat
    46861 tgaaaaacgt ctcatagaag aagggtatca gatcatcgag cggctggttc tcccggacga
    46921 ccgggcggcc ctggaaaaag agctgatccg cctctgcgat cagagaacgc ccgatttaat
    46981 tctgaccacc ggaggaaccg gcttttcctc gagagatatc actcccgaag ccactctggc
    47041 ggtagcggag cggcctgccc ctggaatcgc cgaggcaatc cgggcggcca gcatggaaat
    47101 caccagacgg gccatgctca gccgggcagt gtccgtgatc cggggaaaaa ccctgattgt
    47161 caacctgccg ggaagtccca aagcgtgcat ggaaagcatg gacgttttta tggatcagct
    47221 gccccacggc ctgtccctac tgcgcggctc tgtcatggac tgcgggcgca ggcaggaagc
    47281 gccggacgcc ggcagaggca gatccggcag aatctgataa cgcttcacta acatgcagac
    47341 gataaacaac gaggaatacc atgaaaatat caaaaaaacg ccttatgttt ccccttcttc
    47401 tggcagctgc ggccgcagtg ttctccggct gctcttctct cttatccggc gatcctgacg
    47461 gatcgtcctc tgaatcctcc gagctgacag tattcgccgc cgccagcctg acggaggcgc
    47521 tggaggagat tgcggaggaa taccagaagg cagagcctga cgtctcgctg atttttaatt
    47581 ttgactcgtc gggaactctg aaaactcaaa tccgggaggg agctgtctgc gacctgttcc
    47641 tctccgccag tccaaaacag atggatcagc tggaaacaga gtcccattcc ctccttccgg
    47701 aaagcaggat cgatctgtta gaaaaccagg tggttctggt aacgccgaag gaaaatgaga
    47761 agaatgtgga cagctttgat tctctggcag agcatctgaa ggcaggggat atccttctgg
    47821 ccatgggaaa cagcgacgtt ccggcaggcc agtacgctga gaaacttttg tcctggtacg
    47881 ggctggacat gagagagctg gaatcaaagg ggctcgttac ctatggaagc aatgtgaagg
    47941 aggtcgccgc ccaagtatct gagggcagcg cagacgcggg catcatctac agcaccgacg
    48001 ccttcagcgc aggtctccct gtactggaca gggcctctga ggaaatgtgc gggaaggtgg
    48061 tctatccggc ctctgtgtta aagtcttccg ggtgccaaaa ggaggcccag gactttttgg
    48121 atttcttatc cggccccaaa gcccaggctg tttttgagcg catcggcttt tctatggcag
    48181 aataggaggg cggatatgga ttggtacccc ttgtggaatt ctctgcggat tgccgccgtc
    48241 agcagcgtcc tggtcttctt ttcaggaatt ggagccgcgt actatgccgc taagcttccc
    48301 aggcttttaa agggctttct ggacgttttt ctcacccttc ccatggtgct tccccccaca
    48361 gtggtgggat attttctcct gcttttagtg ggaaacagac gtcctctggg catggctctg
    48421 gagaatctgg gactgcagct tgtcatggac tggaaaggcg gcattctggc cgctttcgca
    48481 gtgtcctttc ctctgatgta ccgcacggcc agaggggcct ttgaaagctt cgacgaaacc
    48541 ctggcacagg cgggaaaaac tctgggactg tcaaacgcct ttattttctg gcgcatacgg
    48601 atgcctgttt gcaggcaggg aattctggcc ggagccgttt tagccttcgc cagggccctg
    48661 ggcgaatacg gagccaccag catgctgatc ggctacactc caggaagaac cgccaccatc
    48721 tccaccaccg tctatcagat gtggagaaca ggagacgacc gccaggcctt tttatgggtt
    48781 ttcgtcaacc tggctatctc tgcagccgtg ctgctggctg taaacggcct ggagcagaaa
    48841 gacagacaga aaaagaaagg agcgcctgtt gctgagtgta acgattgaaa aacggctggg
    48901 aaattttctt ctgaagacag attttgagac tgaggaaccc atcaccgggc ttctgggggc
    48961 ctccggctgc ggaaaaagct taaccttaaa gtgcattgcc gggctggagc agccggaccg
    49021 gggcagaatc cttctggacg gcgtcgtctt atttgactct gacgcaggca tatgcctgcc
    49081 tcctcaaaag cgccaggtgg gctatctgtt tcaaagctgc gctctctttc cccacatgac
    49141 tgtaaagcag aacattctgt gcggaatgca gaaggagaag gaccggagca gacggcagga
    49201 aagcctctgc cggctcagcc gccttctccg cctggaatct gtgatggatt taaagcccgg
    49261 ctccctttcc ggagggcagg cccagagaac ggctatcgcc aggattctgg ccagccgccc
    49321 caggcttctc ctgctggacg agccctttgc ggctctggat tcctatctga gggaacagct
    49381 gcaggcagaa ttaaaggagc ttctcctctc cctggagtgc cagaccgtgc tggtgaccca
    49441 cagccgtgac gaagcctttc tcctctgctc ccgcctggca gtcatggaca ggggaaccat
    49501 ttctgccgcc ggtggggtaa aggagctttt tgaccgtcca aaaacagtgg ccgccgccag
    49561 gctgaccggg tgcaaaaata tcgcggccgc cagaaaaacg ggagatttta cggtggaggt
    49621 gcccggctgg ggcatctgcc ttactgcctc cagtcccatc ccggacggac tccgggcagt
    49681 gggcgtccgg gctcattcct ttaacccggg catcgccaca aaccgctttc ccgccgttct
    49741 ctgcagccgg atggaggaac cctttgagca gctgtttctc ttccggtttc agggacagag
    49801 tcctgacagc ccgcctctct ggtggagact tccaaaagag caggcgcctg acttttttcc
    49861 cgccgctctg ggagtttcgc tggagcaggt gctgctgctg acataaaatg caatgaaact
    49921 atgcggccac gccaaggctc acggcaggct gcgttttctt ctttctcacc aagctcagga
    49981 ggtgcttctc tatgataaaa gatattattt cttccgctgc cggcggacgg ccccttgttc
    50041 tcgtatctgt agtttcttct aagggatcca ctccccgatc tgccggagcc atgatgactg
    50101 tagatgaatc tggccttctg gccggaacca tcggaggagg agccttagag ggccggtgcc
    50161 tggaggaggc cgtctccttc ctgaaaaggc tgggaagcgg cggcaaaaag gcccgtccct
    50221 ccgggtttct ccgctctttt tccctgaata acagccaggc cggggatctg ggcatgatct
    50281 gcggaggctc cacagatgta ctcttcaccc ctgtcctgcc agaggatcgc ggcgcctttc
    50341 gggaggccct ctcctgtatg gaagccgggg aggccagctt tcttctgctg cctctggacg
    50401 gctccgctcc tgcatttcaa aggcagccag gagacggctc ccagtccttg cgaaaaccgt
    50461 gtctctgcac tgcggacagc cgctcctgtc tctccattcc cctaaccgcc tccagccgaa
    50521 tcttccttct gggaggcggc catgtgtccc tggatctgtc tctgcttctg gatcggctgg
    50581 aatttcccta ttttgtcatt gacgacaggg aagaattcgc cagccgggag cggttccaga
    50641 aagcagccaa aaccattgtg attccccttg aaccggccct tctctccgag gcgctgacga
    50701 aaactctcgc tccccgggaa actgacgcct tctgtattat gacgcgggga cactctggag
    50761 atgaggcagc cctgcgcttt gccctgtcca cgaaagcctc ctacatcggg ctgatgggca
    50821 gccggaaaaa gcgggaggcc atcttttcca ggctggaaca ggacggcttc ccagacgtcc
    50881 gaagccgcat catcaccccc atcggcctgg atatcagggc ccagacaccc gcggaaatcg
    50941 ccgtctctgt ggccgcccag ctgattgcct ggagagcagg tctcagctga ataccctgaa
    51001 ttccccttcg ccttccttta acggcacgtc ggccatggtc atggagtcga tgacaataaa
    51061 ggttccctct ttcagtcggg cgatcagcct ctcaattttc tccggctctc cctgcacctc
    51121 catctccacc cggccgtccc agagattctg cacccagccg gtcaggccca ttgccctggc
    51181 cgcatacagg gcgcggtaac gaaagcccac tccctgtacc cagccggaaa agaaaatatg
    51241 ttttctaacc atgtagtatc ccttcttcct gcagcgtatc cacgcaggat ttcatcattt
    51301 tcgcagtcat tccccagatc accagatctc cgtactgata aaacagcacc tcataccgtc
    51361 cctctctcca tcggtaatct cttccctgtg gaatcagatc gtagggaaag ggttcctccg
    51421 gcacggtgag gattttcgcc gtgcggtgca gaggcgcgtg atcaaagaac cactggagcg
    51481 gtatttttat gatttcctct gtctcctcct cagaaaaggt tccctggtat cccttaagct
    51541 ccgccagaaa cgggtagaca gaaaagccgg ccggaatctc cagataatcg caggccatga
    51601 gaaattccgc ctgatccggc tggatcagaa gctcctctga cagctccctg agagccgcct
    51661 cccaagggct ctcccctggt tccatgctgc ctccgggaaa gcagatttct cccggctgag
    51721 tcttcaggct tcccgcccgc ctctcaaaca gcacggcgta ctgcccctgt tcccggataa
    51781 tcggaatcac aactgcgcag tcgcgccgcg cgttccatcc gacaggcctt ggaatcctgt
    51841 ttttcagaga cttcatcggt ttccgccttc cagaaaccac tctgccgcct ggttaaattc
    51901 caggctgttt tcagaagcga taaagtgggt tccgtttaac aggcacagac ggcttccagg
    51961 tatgagacgg tgaattttct tcgtgtggcc tgtgcggatc atatcctttg ttccggcaat
    52021 caccagcact ggctttctca tggttttcag gtatacgggc ctgatgtgcg gttcctttat
    52081 catcagcccc ataagttcct ttttctttct ggccttctct aaaagatacc tgtcgtcttc
    52141 tgttttatgt ttctttctct cccccttcgc gattcgcaga cacgccttcc aataggccag
    52201 ataaatattc ttaaagacgc ctgccttcat tccccacgga ttcagattgg ctccgtttaa
    52261 gagcagcctg tccacatact gggggtggag aatcgtaaaa atcagggcga tatttccccc
    52321 gtcgctgaag cccagaagaa tgatccggcg cagccccatc tcgtccagaa agctctttaa
    52381 atctctggcg aactggcgca gagtgaaggg agccgttccc cgctctgatt ttccgtgccc
    52441 cctggtgtcc acggcaatca ctctgtattt ttttgaaaaa tattctatct ggtttttaaa
    52501 ataggagctg tcctccccgt ttccatgaag gagcaccatc ggctgccccg ttcccttttc
    52561 ttcataatgc agttttattt tcatctttca tcctcctttt gggcgtccgc ccgcttttct
    52621 ccgtactcct ccaccagatc ctcgatgata agaaggccga tggggcctaa gagcatccca
    52681 agaattccaa acagtttcat tcccacataa atcgccgtca atgtctccag gggagagagg
    52741 cccattttcc ctcccatcag cctggcctcc agaaattctc ttgtcaggca gcagattaaa
    52801 aacagaagcg ccaggactcc cccctgataa aaatggccct gcgccatggc cacaacgctc
    52861 cacggaatca gaacggcccc ggccccgaac agcggcagag cgtccagaac gccgatgact
    52921 gcgcccagca gaatgctgta gggatttcta atcagcaaaa gtcccagagc gcagagacag
    52981 gctgtgacaa gcataatcac aagctgcgtt ctcagccatg cgctccctgt cataatcagc
    53041 cttcttccaa acagggcaaa ttcacggctg aacatggact gccttctccg ccttttcatc
    53101 tcgtccatct cctgaagaga cagaacagcc gccataaaga atacggctgc catcacaaag
    53161 gccctggcgc agaaagaaag cgctgccaca gaattgacag ccagactgga catggccgcc
    53221 tgtctgagag tccgtgtcat ggcggtaatc atttctctgg cagcctgcac cagcgcgccc
    53281 tccctgaggc ggcagaaaac ctccgctgta cggcacaggg aagtcagcca ttgatccagc
    53341 cgcatcatcc acccgggcgc cgcgtgaatc atctcgttgg cctcttccat aagacggcgg
    53401 ctgccgcaga acaggagaag ccctgccgcc gctgccaaaa ggagaagctc cgctcctccg
    53461 atgacgccga taggcacgga ataccgcctt cccctgatgt taatctgaag acgtttctca
    53521 atccacgctg cgccgggacg cagcacaagg gccgccagat aggcggcggc aaagggaaga
    53581 atcaggggaa gaaaatattt aaagctgata taaactccgc ctgtcacgga aaggatgacc
    53641 agggcttttc gctgcttttt tgacaattcc ggcaccattt cacctgcttt ctattatttt
    53701 ttcagctgtc cgcttccata aataatagta tggcagaatc atttcctctc catgcgccgg
    53761 ctgtttttct caaatcccag tttcttccct gcgccttttt gcatattctc cttcagactg
    53821 cttatactag ttcctgtaca aaagaagtac aaatcataaa tgaaccaccc atggtaagtt
    53881 cctcaaagca ctaatgaaag gcttacaaaa gagaagctta caaaagatgt gggcctgtct
    53941 tcctttcaag aggaaggcgg gcctgttttt ttcctctggt tccgtgccgc cggggcgttt
    54001 cagccctcta ctgtgaaaca gctgaacttt ctcccggctg acaggaagcc gccggaaaca
    54061 ggcggaaggc tccgccctgg ggcttcatgg aaaaggtcac cggctccttc gtcacagggt
    54121 gggtaaagga caggctgacc gccgccaggg ccagagggcc ttttccccct tccatggaaa
    54181 cggccggatt gtattttgca tctccccaca gaggcaggcc gtggcctgca aactgtaccc
    54241 gaatctggtg gtggcgtcct gttttcaggt gaatttccac aagcgtcagc cccttctcct
    54301 tattttctcc tatgacgcgg taggacagtt ccgctgtctt tccttctgga tccgagttat
    54361 ccactattct ggaatagttg ttttcccggt tcatcgacaa tttgtccaca aagttaccca
    54421 cattatccac aggttttcca catatcactg catgataaat ttttgtcact ctgtgggcct
    54481 gaacctcttt acttaaaaag gctgccgcct ccttcgtttt cgcgtaaacc atcacgcctg
    54541 acaccggttt atccagtctg tggataactc ccacataggg ctcctgggcc tgtgtggatg
    54601 aatttgtgga cattgttgtg gataaacctc tcccttcctg cctctctttc ctcctcctgc
    54661 tgcgaagcag ataattttta atttcgctga ccatatccgg ctccagcttc ctgctggcct
    54721 gggactccag tcccgccggc tttacagcga ctaaaaccgc gtcgtcttca tataatatct
    54781 taatcatact gccgtctcct gcctttgtct ggatttcatc tatctttatt ttactatatc
    54841 tgccgctgtt cagctatgaa aactttccct gtttcttctt gcatttatgg agaaaaaaga
    54901 gtatagtata agaaaatata tgacgtagtt tcaaaaacta catgtagaat tattgataac
    54961 cttgtcgaat tttaaggagg tttttctatg aaatgtattg cagacctgca cataaaggat
    55021 cctggaagcg ctctgactca ttttattgcc ttcgtgggat cggcggcagc agccgctcct
    55081 ctgctgatga aggcggccgc ggagccggac gccagccgtc ttcagatcgc tgccctggcc
    55141 gtcttcattg tcagcatgat tcttctgtat gcggccagca ccgtctacca cactctggat
    55201 atctcagaaa aggtaaaccg gcttctgcgc aagcttgacc acatgatgat tttcattctg
    55261 attgccggaa cctacactcc catctgcctg attgtgctgg ggaaccggtc cggttttctt
    55321 ttgctggccc tggtgtgggc catcgcggca gccggaatcc tcattaacgc cttctggatc
    55381 agctgtccca agtggttttc ttctctgatc tacatcagta tgggctgggt gtgcgtaacc
    55441 gctttccggg aaattatcag cgcgcttcct ccggcggcct tcagctggct tttagccgga
    55501 ggcattattt acacggccgg aggcgtgatt tacgccttaa agctgcccat ttttaactcc
    55561 agacacaaaa atttcggctc ccatgaaatt ttccacctgt ttgtcatggg cggaagtctg
    55621 tgccactatg tggtcatgta tgcgtttgtg gcgtagaagc cctcaccttc acatccatgc
    55681 ttcccgaccg gaatccctcc agatccaggg taatataggt aaatcccagc tctttcagcc
    55741 gctttgctat cctctctctc ttctccagca cggcggcgaa ctgcccggcg tctgtctcca
    55801 gcctggccgt gtccccgtgg acccgcaggc ggacgttgcc aggcttttcc tctgaaaaca
    55861 gctctctatt taaaaactcc tcgccctcct caatccgctt cagcagatcg tagtccagcc
    55921 tggctccata gggaagcctg gtggccatgc agggggcgga ggggcgggaa gcggcggaaa
    55981 tgccgtattt ccctgccagg gccttcactt ctttcttggt aaggccgcag gatgccaggg
    56041 gacttttcac ccccagctct ctgagggccg ccaggccggg ccgatactcc tccaaatcgt
    56101 ctgcgttcgt gccgtctaag agcagggagc atcctttttc tccggcaaat tcctgaagcc
    56161 ggagaaaaag acggcgtttg cagaggtaac agcggttgac cggattattt ctcagttcct
    56221 cctgctccag ctcgtcgact gagaggacaa cgtggtcggc gtccatctcc ttagccacct
    56281 ttctggcgtt ttccaggtcg cagacaggat gcagcatagt gtcaaaggta acggcccata
    56341 ccttcgtccc gtgccgcctg gcggcggcgc aggccagctt taagagcaga ctgctgtcca
    56401 cgcctccgga aaaagccaga cagaccggtt cctttccata ctcgtccatc acagccgcca
    56461 gctgtttttc cttctcctgc agctgctgtt tcttgttctg attcgcagta aaatccatgt
    56521 gtccctcctg ccgtctagtt tctgtgttca tgctttccag cggcctcttc cgcctgggat
    56581 ctggccagat gataaacctc tgcaaatccc atccctgtct ctctgctgat gcgggcaatg
    56641 ctttcatatt ccggatagaa acgctcctct ccccggaaag agcacatctt gaccgccagt
    56701 tttccaaggg gcaggtccat ctcctccaca cggcggttca aaaccgtcct ctcaaccgga
    56761 tagcggcgga ttccgatggt agttgtgtgg gagaagatca gcccttccat gtcctcaatc
    56821 tgcgccctgc ggcagagagt gtggaggacg taggccggac ggctcttttt catcactgcc
    56881 ggcgtgtacc acacatcggc ggctccctcc tccagcagac attccatcag aaatccaagg
    56941 gcctctccgc tgcagtcgtc gatattggtc tcaatcacat acatggaatc cggctcctga
    57001 gttcctgaaa atcccggttc tgccttccca gactgcttct gctctttctc cgtctgctcc
    57061 tcttcctctg gcacaagaat catggcccgg agaatattgg cgtttttaaa gtcctttgtg
    57121 ccggctccca ctccgatttt ttcgatgata tagcgctccg gcagctcctg ttctgtcctc
    57181 agacatccgg cgatggctgc ccctgtcggc gtcaccatct ccccctcgtt atccgtcaga
    57241 cgcagagtca ggccgcaggc cgcagcaatc ccggctgtag ccggaacagg cactggcatc
    57301 acgccgtgct ggcatttcac atacccgcgt ccctcagaca gaggagaaac cgccacgcgg
    57361 ctgattccca gatcgcggat gcacacggct gtgccgacaa tgtccacgat ggaatccacc
    57421 gctcctactt catggaaatg cacctgttcc accggaagcc cgtgggctct ggactctgcc
    57481 tccgccacca ggcggaacat ctccttcgcc agacggcgcg cctcttcatc ctccagacgg
    57541 tcaatgatct ggtaaatatc atggacattt ctatgcacat gagagtggtg gtgatcgtgt
    57601 ccgtggccat gatcatgggt atggctgtga tcttcgtgat ggtggcggcc gtgatctcca
    57661 tgatggtggt gatcgtgatc atggtcctcg tgatggtcat gagcatggct gtggccgtga
    57721 tcatgttctt cgtgatcgtg atgatgatta tgatcatgat cgtggccatg atcatgctcc
    57781 tcctcttcca gatgcacatc gaaatcatag gcgtcaatgc cgcatttctg cgtccgacca
    57841 aagtgcaggt gatatccgcc gattcccagc ttctcaagct ccttcataag acgctcccgg
    57901 ctggcgccca ggtctaaaag cgcgcccact gtcatatctc cgctgattcc tgaataacac
    57961 tctaaatata aaatcttttc cttctccatg gtctgttcct ctctgatttc tcttgtcctt
    58021 ctatggtttt ctctgtctgg cttctccgcc tgctttccct actccgcctt tctctccgcc
    58081 aggcggttaa tctgggcggc cagatatccg gctccgtagc cgttgtcaat gttgaccgcc
    58141 gcaatcccgt tggcgcagga gttgatcatg gtcagcaggg cggacaggcc gtggaagctg
    58201 gctccgtagc ccaccgaggt gggaacggca atcacaggat tctccaccag cccggcaatc
    58261 accgttccca aagctccttc cattcccgcc acggcaatga tgcagttagc ctttgcaagc
    58321 cgctctctct gggccagcag gcggtggatt ccagccaccc ccacatcgta aatccgttct
    58381 gcgcggcagc cgaaaaattc cgctgtcctg gcagcctcct ccgccaccgg aatatctgct
    58441 gttcctcctg tgcagacagc tacgcaccct gtctgctgtc tcctgctctc cggcctgctg
    58501 gcggaaagaa tccgcgatat gggatcgtac tcaatctggg gaaccgcctt cttcaccagc
    58561 tcgtactgtt ccttcgatgc ccgcgtccca aatacctctc cgttttcctg gtacagcttc
    58621 ttaaatatct ccgccaggaa ctcgtccggc tttccctggc agaacaccgt ctccggaaaa
    58681 ccggaacgca gcttcctgtg caaatccagc ttcgcgtagc ccagatcctc atagggcaga
    58741 tttttaagct gtttttccgc ctcctccacc gacagggcgc cgtccctcac ctgatgaagc
    58801 atttctttga tatccatatt tttttcctcc atccgtctgt ctgctttccg ctctgtctac
    58861 catcctatca cccgatggca cacttcctca agcagttttt ctgaatgact gacagcaatg
    58921 agaccgatat tcctgcgctc cagctcttcc agcagaaaca gccagatttc cttctgggaa
    58981 gccagatcaa gcatggccgt tatctcgtcg gccaggagaa acctggtttc ctctcccaga
    59041 gctctggcaa tgcagaaccg ctggagttct ccccctgaca gctcgtccgg ataacgcgtc
    59101 agccattcct ccctgattcc cagccgctct gtcatctctc ccggcgaaac gccgccttcc
    59161 cggagaacct ccttcatcct ccacctggga tttaccgact gttccgggtg ctggaacacc
    59221 atctgcaccg gacatcttcc gcgaaaggag ctaaggggcg cgccgtccag cgttacgctt
    59281 cccccttccg gcttctcata gccggccaga attttgcaga gggtcgtttt ccccgatccg
    59341 cttctggcca taaggccgat ccgttccccg ctgtccacct caatggagca gtccgttaaa
    59401 atctgtctgc cccttttttc gtaacgaaac gaaattccct ctgctttaag cttcatccgt
    59461 cttcctccta atttcctccc tccacggttt tccctgcccc ggcacagcgt caaacagacg
    59521 tctggcataa aggtgagatg gaggcgcggc aagcgttcca aggggtcttc ccgcctcgtc
    59581 cttcgccatc tgaagttcct ccgccacagt tccctcgtaa aaaatcaaaa tccggtcggc
    59641 ggtctgcaga gccagctcca gatcgtgggt gatcacaaac acgcccaccc cctgatctgc
    59701 catttcccgg aaatgtccca tgacctgaag ggcagcctca gcgtcaagcc ccggcgtagg
    59761 ctcgtcggct atgaccagtc tggggccttc catcatggcc cccgccgtca gcacgcgcct
    59821 ggccattccg cctgacagct caaagggata tttatccgcc gtctccccgg gaaggccgta
    59881 ccggtctaac agttcctcca tccgcttaaa ggaagccaga tcctttcttc cttttctgat
    59941 ctggtttccc gcccgcatca gaggatccag gccgtttact ccctggggaa tcagggcgat
    60001 ctctctgccc cggagcgctc tcagatactc cttcgtcagc tcctgtccct gaaattctat
    60061 ggttccctcc gctgcggcct gttccggcag aatccccatc accgcctggg caagcaggct
    60121 ttttcccgaa ccgctggccc ctgccagagc cgtaatctcc cctgcgcaga tctccaggct
    60181 caaatcacga atcggctgaa tctgtctctt tttaaagcct ctttcctcct gaaaggaaac
    60241 ggaaaggttc ttcaccgcca gcagcggctt acgcttttca ttcatctctc ttttgtctcc
    60301 tttcgccagt cccatatttt gctcttatct catttgtaaa acaatttacc gccagatccg
    60361 gcgtttcctg ccccactgcc ttcccatgct ctcaaacagc agaaccgttc ctgtcagggc
    60421 caggcccgga aggagggcca gccaccattt tccagtgatc agatatctca tgctctccga
    60481 taaaatcatt cccaccgacg gctcctccgg gggcagtcca aatcccagga aggtaatgct
    60541 ggcctcgtgg aggacggcgt ggggaaaggt caggatcagt cctgtcataa actgggagag
    60601 cagctggggc gctatgtgct ttcttataat ctgaagcctt gacattccca gcctggctga
    60661 aatcttcaca tactggcttt cccgtatctg cagggcctcc gcccgtatca ccctggccaa
    60721 agacggccag tgggtcaggg caatgcccgc cgcagctcct gtaaagcctt ttccgcaggc
    60781 ataggaaatg agaatcagca aaagcatatg gggaattccc ataatcagat caatcagccc
    60841 ggaaaccgcc cggtccgccc attttcccat ggctgacgcc gttcccagaa caagggccgc
    60901 cagcgcgctt aaaaaggccg ttacaagccc cagccggatg cttaaagaca ggccggccag
    60961 cgttctggcg aacatatccc tgcccagcca gtctgttccg aacagaaatc cggcctgggg
    61021 aggcaggttt ttcctggcga aatcagccgc tcccgcctgc tctgaaagcg ccgcccctgc
    61081 cgctgtaata aaaagcagca cagaggctga aatcacaata ttccacagag ggctggctgt
    61141 cctgcccgga cgtttcgcag gctgtctttt atatgtcccg ctttttcggc ttctgttccg
    61201 gctcctctta tcttttatgc gtttgaaagc ttctatcagc tttccatatt ttctctttct
    61261 gtttgtctct gccctcttct gttcttcgtg ttctctgtcc gcgctccctc tgtctttgct
    61321 ccgccttcga ttttcagccc ggaaaccgcc cattctcgga tccaccgccc ggtataaaag
    61381 atccgccgtc agatttcctg caaacacgaa aacagcgctg ttcagggtaa ttcccagaag
    61441 cagaggcacg tcgcttccaa ggccagccgt cacggcggcc tggcccagcc ccggatagga
    61501 aaacacctgc tccaccagca cagaacctcc gaaaatctcg ctgatggagg caaactgcag
    61561 ggtaatggcc ggcagaagca catttctgag accgtgtctt accacgatct gcatctcgct
    61621 ctctcctctg gccctggcat agagcacata ggggctttcc ataatgtccg ccatttttgc
    61681 cctggtgtgc agggcaatgc tggaaattcc cgtcaggctc agggtcagcg ccgggagaaa
    61741 ggcgtgggaa atccggtcgg caatggtcac ctgccctgcc tccattccaa tgggaacgcc
    61801 caggccgatg ggaaacagct ccagatggac ggaaaaaatc aaaagcagca ccaggccgat
    61861 ccagaaggag ggcgtgctgg ccgtcaccat acagtatcct gtaatcagcc gatccggcca
    61921 tttcccctta aaggcgccgg ccagaattcc gagcatgaga ccaaagactc ccgacagaac
    61981 ccaggcggaa gccatcagcc acagagagct taaaaaacgc tctcccacta cctgggccac
    62041 cggtcttcgg tagagaaggg aggttcccag atctcctgac aggacgccgg acagccagga
    62101 gataaaccgt tccaaggccg gtgttcccac accccagtat tccttcagtt cctccacctt
    62161 ctcctggctc atggccccca gagccgcctg ccccacattg ctctgaagcg gatccaccgg
    62221 agagagggaa accaggaaaa aagaggcggc gctgacgaga agcaggagga caagcatccg
    62281 gacgcatttt ctgagcatcc atccggctgt ctgtttcatg gcgtatttct ccttctttct
    62341 ctattcccag aaccactgat ccgcgttgtt tacaacagac cagccgtggc cgtggggctg
    62401 aattttctgc tctcccgtgt tgaggccgtc tctcacccaa taaaggtgat ccacgtttac
    62461 cagccagatc cagggcgcgt ccccgattcc ggaagctccc gtcccgccat cccactgggc
    62521 ctttttccac agctcatagg actcctccag gtctgagctt tccagggcct gctccatgta
    62581 ggcgtccacc gtctcgttgg agtacgggga gtactgggcc gttcccagag cctcgtctgt
    62641 gtggtaaatg ttgtagagct ccatcggcgt gtgggctccc cagccccaca tcagcggctg
    62701 gctgagcgcg tctgtgtagg ccgtatccca gcccacaccc ctgacagaag cctggattcc
    62761 cagactggcc agctggttgg aggtatccat ggcaagggcc tggcggacgg aatcgtctgc
    62821 cggatataaa atttcaagct ccgccctggt tccatccttt tctctgattc cgtctgcccc
    62881 ctctgtccat cccgcctcgt ccagaagtct ggccgcctgc tccgggtcaa aatccgtctc
    62941 cgcctccgga ttgtaccagg gcagcttgtc gcacacgctg taagccgggc ttccgaagcc
    63001 gtttaacaca tggtcaatca tagcctggcg gtcaattccc aggttaatga cctgtctcac
    63061 ccgcacatcg cttgtaaaat cattgccccg cttcacaccg ttttcgtctg tataggccgg
    63121 cacggcaggc aggttgaagc ctcggttgtc cacgctctcg catgccatca ggcggtaccc
    63181 tgaaacctcc tgctccccgt aggaggccgc cgtgtaagcc acgtctgcct gtcccgccaa
    63241 aacagctgca aaggccgcgt cctcctccat aaagagtacc gtcagctttt ttagcttcgg
    63301 agcctccccg tagtaatcag gattcgcctc aaaaatcacc tgctgcccct tgtcccactg
    63361 cttcatgaca tagcggccgg atccaatggg atgcattccg tagtccggac cgtaggcgtg
    63421 ctccggaaca atacctgtgg aagccatggt gtagggccag atggaatagg gatgcttcat
    63481 atgaaagaca accgtatcct catcctctgc ctccgcccgg tccagcatgg taaaatcatt
    63541 gactgagctg gtttccttca gggtattgta ggtgaaggcc acgtcctctg cagtcaaggg
    63601 ttctccgtct gtaaacaccg cgtctgtcct gatatccacg gtccaagtca gaccgtcctc
    63661 cgaaacgtcc atctctgtgg ccagatcata gccgatggtc agatcctcct ttgtaactgt
    63721 gagggtactc tgaatcagcg gctcgtgaac gtgctccccg gctccccatc cgtaagccgg
    63781 atcaaatccc gattccggtt ctgattctgt ggtcattacc accacggcag aagtcttttc
    63841 aatttcctga tttccctcca gctctgctgt gtggtttcct gcgtgttcta tctcctgtcc
    63901 cccttgctta tgtctgcatc ctccaatcaa aaagaccgtc attatcaggt acagtcccca
    63961 tgtttttaat ttcattttcc ctcttttccg ccggctatcg gctctcttga aaaaatgcca
    64021 gaaaggcttt tctctgtaca caaagaaaaa tgccttcctg gcattgctgt atatagcttc
    64081 tttttattag tcagctttcc gtcctctgtc ttcttcccgc agattggtct gctgttccct
    64141 gcttgtgcag agtctgtaaa atgaaacaaa atcctggaaa tcttcctgtt cattataaaa
    64201 gaaacagatt ttttcgtcaa tctatttcct ttcccttgtt tttaatatat tttttacttt
    64261 tgttttattt tcgttaatct ttttttattt ctattgttct gacaatctat ttaatgtata
    64321 aatatgatat catattttct tcagaaacaa aaaaggaaaa ataccgtttt tgaagttgat
    64381 gtgtgtatca aataacaaag gagtgattac tatgaatttt gatccagcta cttctacact
    64441 gactttggat ctacttgcaa ccaccggatt tggctgtgta atggtttatc tgggaaaagg
    64501 cattgtgcgc cgtgttaagg catttcagga ctggagtctt cccgctcctg ttatcggcgg
    64561 tttgattgtc gctttaatcc tgagtttttt aaagagcaga ggaattttca ctgttcagtg
    64621 gacctccaca ctcagcagcc atctgatgaa cctgttcttt acctgtgttg gtttcggctt
    64681 cagccgtacc ctgctggacc gcggtaaaaa gttctgtgca ggcattgctc tgtctgttct
    64741 tttactcgta ctcttacagg gaattctggg aattgccgta gcatctgctc tgggaatgca
    64801 ccctttaatg ggaattcaaa ttggaacagg cgccctggca ggcggcgttg gaaccacatc
    64861 cgcttttgga cctgtttatg aatccatggg agcagtaggc gctacagaaa tcggtgttgc
    64921 tgcagccacg ctcggtatga tcatcggaag tttaacagga ggccctctgg ctgttctctt
    64981 aatcaaacgc cacaatctaa aatcggatcc aaatgaatcc gcattcgaag aggactctga
    65041 atctgttttt cctctgaacg ccaaaactct tctttcctct gtctgcatga ttactatcat
    65101 tgcggcctgc ggtattccaa tttacttact gttaagccag attccttaca ttgaaatgcc
    65161 ttattttatt ggatgccttt ttgcaggggc aattgcccgg aatgttctgg aagcccttca
    65221 tgtagagatt cgcccacagg aggtagaaac aatcgaacac gtttcccttg atattttcct
    65281 tgccattaca attatgacta tggatttaac caaaatcgca ggttctgctg gtcccatgct
    65341 ggcaaccctt gttattgtat ccatagccac cctgcttttt acttacttta ttggtttccg
    65401 tatgtacaaa agcgattaca atgcagcatg tatgtgcgcc ggattaattg gcatgggaat
    65461 gggttctgga tccaacgctg ttgccaacga gagagctgtt atggaaaaat atggatactc
    65521 ccatattgcc tggattcttt atccagcctt ttcagttctg tgtgtagata ttttcaaccc
    65581 gcttttcatg tcgtttgccc ctggactgat gggtttcgga ggctgatttc agccaaaaaa
    65641 cggccggatg ccgccctcaa aaagtgcggc atccggccgt tttgcttgct ttacattaca
    65701 tctgaaaaat gcggtcttag ttttctgaat accttaagtc ccagaaacat taaaataaac
    65761 gtcactcccc agaaatagag agtcagtgtc ggacgctcaa agaaccagtg tccctccagc
    65821 atactgtctc tgaatccagt ggaaatatag tagaacggat tcagtttaaa cagaggcagc
    65881 agccatggat gagcattggt aaacatggat tcatggtaca taataggcgt cagccacatg
    65941 ccaaactgca gacagatgcc cacaatctga gccatatcct taaaaaatac ctgaatcgag
    66001 ctggtcaggt acgtcactgc cagcgccagc atcgacgcgg cgaaggagta atagagcacc
    66061 tgaatccagg tgataatggg gaaatgtccc cccaccaggt aaagtcccac catgatgacc
    66121 aggaagcagg catgtaccat aaagcaggaa atcattttaa taatcggcag catttccacc
    66181 tggaaaacta ccttctttac cagatagtga tactcctgca gacagtttgt ccctgtattt
    66241 aaagcctcgc tgaaatagaa ccagggcaca attccaggca ccatccagat gacataggat
    66301 gctcccggaa caggcggagg actcttaaag ccatactctc caaacagaaa ggcatagatc
    66361 agaatcgtca caaggggctg gataaacatc cagatcactc cgaaatagga gcctacaaac
    66421 cgcttcttaa aatcagcctt ggacaaatcc cagatcagct ttctcttctc tataatccct
    66481 ttaaaaagag aagtataata gttcattctt ttccctccgt gtccgctttt aacattaaaa
    66541 acggaaggta tccttaaaac cgccccattt ctgatctttc tcagaaataa tcagctccat
    66601 tccctcttca atcggccact ctacgccaat ctccggatcg tcccaggcca gtccgccctc
    66661 atcgccagga tggtaaaaat cggtgcattt gtaggcaaac tccgcctcgt cggacagtac
    66721 caggaatcca tgggcaaatc cttccggaat atagaactgc ttcttattct cagcagacag
    66781 aaccacgccg aaccacttgc cgtaggtctc ggaatcagcc cgcaggtcca cagccacgtc
    66841 gaacaccgta ccgcggatgg cgcggaccag ctttccctgc ggatactgct tctggtagtg
    66901 gagtcccctc agcacgccct tcacagacat ggactgattg tcctggacaa ataccatgtc
    66961 aaggccagcc tccttaaagt cattctgatt gtaggtctct acaaaatagc ctctctcatc
    67021 cttaaataca gtgggttcaa tcacataaag ccccttgata tcgcacggag tcactttaat
    67081 ctttcccatc tttttattcc tgcctttctt ctgttttctt tattacaagt ttcacttctt
    67141 catcgtctgt tttcaggctt tccctactat accactatcc gcccgttctg gcaagaacgg
    67201 ggcagcggga acgaggcggg cgcacagtta cttattgcag aaaaaaaaag ttttccagcg
    67261 gctaagcttt tagtagagct tggaaaactt ttttcctctt ccaaacgttt tttcccggca
    67321 tatccccttt cagcggaccg cctaatcctc tttctctttc gcccgatccc tctcctcctt
    67381 ctcgtcgatg gccattttct gaaccagctc tctgagccgc gtctccatct gggactgctt
    67441 gatagtcatg tggaacagct tgacaatcag caggaaaatg acgaacagga aaataaaatt
    67501 ggaggtggaa taggtccccg ccagctccgc cagcacagtg ggcacaatgg gaaatacgct
    67561 gaacaggatc agcataaagg aaaaaccaat ccagaacagg gaatcctcta tctgcagctt
    67621 ggactgcctg attttccgaa gaattaatac ggttgtcaga acagaagcta caattaaaac
    67681 aattctcaaa agcaatgtca cagtcttctc gcctccttac ccttcccgct tccgaaagct
    67741 ctgaatcagc agaatcgaca gcaggatttt cgccatatag aaaacagact taaccggcgt
    67801 caggtagctg gctccctgca ctctctcgtc cataatcaca ggaatttccg ccactctggc
    67861 ccccgcctta atcaggtagg acactgtgtc cggttccggg ccgtagttta atcccccggc
    67921 aaattcgcgt atcatattct ggttaaacat gcggaggccg gaggtgggat ccttgatggt
    67981 tacccccgtt gtcaggcgga tggcccactc aatcagacgg cttcctatca tgcgcatgga
    68041 aagcggcttt tttgccccta caaaccggga tccgatgaca atgtcgtacc cctcctccat
    68101 ctttttcatc atggcctcca ggtactccgg gcggtgctgc ccgtctccgt ccagctggac
    68161 cgcgtagcgg tagcccttct tcgccgcgta tttaagccct gcctgaaagc ctcccgccag
    68221 ccccaggttg actggcagat ctaaaaattc atacccacgg gcccggcaga tttcccctgt
    68281 cctgtccctg gaaccgtcgt tgatcacaag gtagtcgtac tggggaaagc cttttatcag
    68341 gcggtccacc accttctcaa tattgctctc ctcgttgtag gctggtatca caatcagtaa
    68401 atccgacata ttgtcctccg tcgcttgtat atcccgttat ttctatattc ccggcttatc
    68461 ccagtaggct ttgttcatgg taagccccat aaccaccttc ttcggaagcc tgcggtaccg
    68521 ttttcccaga aaatacccca tgtatttaaa accgctgtgt acggccagct gcggaatcag
    68581 ataccatttt ccctttctga gcagaaacgc cgccgtcctt tttaccaggc ggatgccctc
    68641 tccctcagag gaaatgcctg caaagacctc cgggtggtct gcctgggaca ccgccaggtc
    68701 aaaattccgc cgaagctgct ctaaagccgt ataattgtgg gagtggaaca ccacggcgtc
    68761 tgccgcgtag gcgatccggt acccctgctt catggctccc gccgcgtaga tcatgtcctc
    68821 gttgaaaatg gtcttcttta tgaagccgcc cagctttctg taaatatccg tccggtaagc
    68881 ggcgcagaca ttggaacaga aatacgtctt gattcccagt tccttcaggt ctgccataga
    68941 ttttatgcgg ctggtttccg gatagttgaa ggagcgggtg taggtttcaa tcacagaaca
    69001 atcctcaaat ggaagctgcc tggcgtaagc cgccgctatg tcctcccccg cctccagagc
    69061 ctttaccagg tttcccacca gtctggcgtc ccccgggact gcgtcgtggg tcatgcagat
    69121 gcagacgtcg gcgtctgaca ggcggatgcc ccggtctctg gtggccccgt ggtcaaattc
    69181 cgcttttgaa aggtggtata cctgaagctt cggtcccttt ccctctcctg ctgccaaaaa
    69241 ggcggtctca tattctgtgt tccaatactg ctcttctgtg ttcatgataa tcacccggcg
    69301 cagggggtat tcctgctggc tcagacgttt taaaagctcc tcaaagcttt ttcccgggcg
    69361 gtacaccgga atcacagcgt ccactgtttt tatcgttccc tgttccatgg ctgtgttctc
    69421 cattcaactt ctctgtttga actctatttc tcgtaggccc tgtaggcctt tttgtaaaaa
    69481 tgcatgaaaa gctttaccat tgattccggc cacattttcc taaacatggc ggtctcgtcg
    69541 ttttttctcc ggttgtcctc aatgcactgc ttcgtggtag cccccggatg cacccggtaa
    69601 aagatcagag gcctctcgga gcagacaaac cggccgggac ggcaggccag ctggtagaga
    69661 ttgtcccagt ccagggcaaa ctcaaagtcc gactcaaaca gccgatctcc tatcagctgt
    69721 ttattgtacg tgcaggacgg acagcagacg gagttgccga ataaaagcgc cgcccgcttg
    69781 actgccttcc tgtccgaaag tcccttaaac cgcaggggca ggcgcagcag ctttttcacc
    69841 agccagacag cgtttaccag ctgaagcttc ggcgcctccg tctcccgctc catccggaga
    69901 gtggcgtagt cgctgcagaa taccgtcata tccgggtatt tttcatacat ggagaacagc
    69961 gtctctgcat accgcttttc atacctgtcg tcctggtggg cgatagtcac cagatctccg
    70021 gaagccttct tgtaggcaaa cagccagtcc tccctgatcc cgctttcccc ctccctcaca
    70081 tagaggggaa tcctgtattt ttccgccagc tcttcaatat agggactggg tgtggaggtg
    70141 cagcagatga tctccgattt ctgcctctgg caggccagag aggccataca ttcctccaga
    70201 tagggagaat cgccgtaggc gcagatggcg aacgtgtgca gttttctttc cttcttttct
    70261 atcatctcat ttcctcccta cagacacagc gccgacagca cgtccaccgc gtaaacggcg
    70321 tagaacacag ttcctgccag ggccagcacc agcggataat acacagaatt tttcagcttt
    70381 acctgcacgc aggaggggct taccgccagc cacaccaaaa acagaaacgg caggtaatac
    70441 cttccctgaa cgccttcaat ataagtattc ccaggcgggg taaaagcaat gtacatggat
    70501 gtccacacca gcacggcgca ggctccggac aggagaaaaa tccacagtct ctggattttt
    70561 gtcagggttt ttccacagga actcctggta tctgtgagga taaccgccgc gctggccgcg
    70621 tacagcagcc atgggaagga aaccacaccc agatggccca gcgttccaag ggctctctcg
    70681 cccagcacat aggacggaaa actggagaaa atatttttaa acagcaccgc cgcgtaggcc
    70741 agcggctgtc ccagcacgta ggccatctga cccgcctcgc tggtggctcc tccccgcaga
    70801 tctcccgtct cgctgggaga gatgagaacc ggcagcacaa aggaggccat cataagcaga
    70861 aacatggccg caaagccggc ccgcatccag ttcttctttt tcttcgtctc aaaccgatcc
    70921 gcaggaatta aaaagcccat taagatcagc ggcgcataga cggccttgat ccggcatccc
    70981 cagaaaaacg cgcctatgat aatggcaaac tcccgccagg acagccgtct ctccgggttc
    71041 agaaccgcct ccagaatata ggcgcaggac agagccgtaa aggctgtcac tgtcggatcg
    71101 taggagtaga cgcccgccag catcatgggc gccggcatca ggccgataaa ggccagcatt
    71161 ccctttccca ccggcgtttt ccggatagcc agagccatcg ccagggcgta gattagaaga
    71221 tttcccagcc gtcccagctt aaagagcatg gaaaacggca ggcggaatat ttctccggcc
    71281 tttaaaaggg ctgcctggcc cagatagccg gtaaacgtgg tcttattcag gtctgcgctc
    71341 cagcagatgg aaccgtttct gtagtctccc gtctgatcca gatagcggtt cagttctctc
    71401 tgctctctga gccctcccgg ctggttcagc ggccaggtgt cgatcccggc agaaaactcc
    71461 tgaaacacag aaggagatag ctgcaccgga tctctgtaat gggcgatcca gcagctctgc
    71521 tcaaagtgga tttcctcgtc aaagcccacc ttgttggccg gcagggagag ggagagcagg
    71581 aggcctcctg tgagcgcgag gaccagaaac cctgcctccg catggcgtcc aatccagctt
    71641 ctgcagacaa tcagaaagat aactgttcct gcagcgcacc agaagaaaca caggcggaag
    71701 ggattgaccg ccgcctctgt caccgcctca aagcctgtga aagataaggg catggaggca
    71761 aagtcaatat aggaaagtcc cggctcatag aggtctcccc ggctgacgga aagctcaacg
    71821 cagtctgtct ccttccccac aggaatccag gccgtctgta tcgtcttggg atttttgtcg
    71881 agaaaaattt cagcgtccct ctcccgaacc tccccgtact cattttccac ataggccctg
    71941 accgtcatgt tcagaagacc gtcgtaatcg taggaacagg ccacctctcc cacatacgcc
    72001 cccacgggaa tccgtatcgt tccggcatct tccgtcagga ggaggcgctc cccctgatcc
    72061 agccgaaagc cctcgtactc cacctctgac agaggaatcg ggaaatttcc ttccttttca
    72121 ttctgaaaaa gagaaaggtt gcagaacagc tccagcaaaa gcccgaagaa gaatacaaac
    72181 acggtccagg ctcctgcctt taaaagccgt cttctgcgcc ctcctgcccc ggaagctgtt
    72241 ttaaatcctg ctttcgaatc agttcctgaa tctgccttaa cctctgcctc aggttctgtt
    72301 ttaagctctg ttttagaatt cattttcaga tctctcctgg tttcccggcc gcagaatctc
    72361 cagctgtgcc gggataatcc gctcgatatt cctgtgctct aaaatcctct cgtagtcctc
    72421 gatgtagtcc acctcggccc agaagcgtcc tcccacatcc tgcacgtaca cgtctctctc
    72481 ccgcgtcatc tcatacagca cgttctccca ccagacagag tgctgctgct ctccgatcat
    72541 ctggttcatc cgctctgtaa agcagggcag gaaagaggcg gaaaaccgtc cgattccaat
    72601 gtattctcct gtaatatcgt cccctgacag ttcttttccg tattttttca ggacaccgtt
    72661 ttcgtagaaa aacttgtagt ccgccgtctc cttcctggtc tcgtcggcaa acatgaccgg
    72721 actcttcttt tcagccagaa tctggtctaa cagagcctcc tccatgtaca cgtcgccgtt
    72781 catgatcatc agatcctccc cggcctgcgc cgcctcctcc acaaaggaac cggcaaacca
    72841 ggcggaggca atactgtttg tcacgtcata aaacgggttg acataaaact tcactgagca
    72901 gtccttcagc acgtcccgta tcacctgggc ccggtagccc agcacaatgc cgatctctga
    72961 aatccccctg ctctttaaca gctccaccgt ataccagatc aggcagaggc cgtttccaat
    73021 atccaccgta cactttggtt ttcccgacag gtagcgggaa atcctggttc ccctccccgc
    73081 agctaagatt aatgctctca cagaagcccc ctgttctgca tgtctttcaa tgcgcttatc
    73141 aggctgtcat tgtcagcctc cgtcaaatgt cccatatggc cgaccctgaa aatccggtct
    73201 gccagcgccc cgccgttggg gcagacaaaa atatcgtact catcctttaa aatctcaaaa
    73261 atccggtagg cggaaaccgg cgttttgtca gctccctgac cagtaggatg aagcggagtc
    73321 tccccgaaag acaaagattc cgacacaatc tcaaagggca gagatttgat tttctctctg
    73381 aaatcctccg cctggcggcg gattctctca agctccgccg aaagcccctg ctcctcaatg
    73441 cgcctgagcc tcctgttcag ctggatcagc acgctgactg ccggagtgta gggcgtctgc
    73501 cccctctcac cgtcctttaa gtagtccttc aaatcaaaat agatggaccg gaccgcgtgt
    73561 tctttcaccc gctcaaccgc tctctccccc agcaccagga cagacagtcc cggcggcagg
    73621 gctaaggcct tctgagaacc ggtgagaacc agatccacgc cccatttttc cataaagaaa
    73681 tcgtcggcca gaaaagagct gatggcgtcc accagaagca ccaggccgtt tctcctgcag
    73741 aaatcggaga tcaaatccat gtcgtagtac acgccggtgg aggtttcatg gacattgacc
    73801 aggaaaccgg taaagttctt cccctcgtaa gcgtccagat gctctttctt caaagccttg
    73861 ccagactcca gataaatggt ctcgtgggga atctgaagca cctggcacag cttttcaaat
    73921 ctggccccaa agcttccccc gttcaccacc agcacccggt ccttctcagt aaacagattg
    73981 agaaccgccg cctccatggc cgcagttccg gatccggtga gaaacagcgc ccgcgccccg
    74041 tctcccgctc tcacaaaccg cttcatcaga gtctcgtttt ccttcatcag ggcggaaaat
    74101 tccggagtgc ggaagtacgg aatctcctgg gcccccaggc ttcgtatctc ctcgtccatc
    74161 atcaccggtc caactgcaaa attgatcatc ttgatccctc ctgttctcct ggcatgttac
    74221 gcgccttttt ctctctccgg tagaagaaca ccgccgtcag gccaaagcag gctgccagcg
    74281 ccgccatcaa aataaagtag gacagagcgc ctcccagaat gccagccgcc cgcacaaagg
    74341 gggaggacag gcagacggcc agtacgccta ccaccgtata gccgataaag ataaaaggct
    74401 gtttctgcat aatcacaagc gaatagtaaa ataagtttac ataagcgttc cccgcgcctc
    74461 ccagaataat gagaagcagc gccgtccggc agtccttcag tgcgtatccc agcttggggt
    74521 agagaaggct cagcaccggg atgcctaaaa accaggcggc tcccacggcg aacacggtga
    74581 ggccggcgat aatggccgcc agctgcttca caactaccag atagccggaa aactcccgtt
    74641 tcccccagga agccgacagc ttcgtaagat acgggcgtat gacaaaaccc gccaccaggt
    74701 taataaagct ggtgggcatg aaaatagcac cgaataccga catatcgcgg ctggccatat
    74761 tggcgtccac cgcgtacttg gacgcggaaa atacataaaa gtcaataata accgagagaa
    74821 acagaagaaa attgtcccgg aacagccacc aggttttctg tttcctcact ctccagtcca
    74881 cgccggaaat gcagccgatc acagagacgt taaacaaaag cacgcccagt acctgagctg
    74941 cgactgccac caggcaggaa aataccagat tttctgtggc catcagactt cccatgaagc
    75001 aaatcacgga aagaagcgtc cggaatgtgt tggattttcc cgtcagatac aggcgcccgt
    75061 ctctctggaa ttccgcctca taggcgtcgg caaagccgtc gatcacctta tagcctacca
    75121 tgagaaatac gacgagggct ttctccctgg tataggttcc cccatgggca gccacataca
    75181 gaaggccgaa ggccagagcc gccccgcagg tgataaatct cagcctcagg tactctccaa
    75241 aggtatacct ctgcctggta tctgtgatgt gaaaggggcg gatgccgaaa taggccacca
    75301 taaacatatg ctggccaaag gtcgtaaagg cgaaggtaaa atcgcctccc tgatcctccc
    75361 ccaccacctg aatcactgca atggtcagca tcatggaggc gaaagcgtag agaaagcttc
    75421 cgatcatatt ccagatcatg tttctctgct cgatattctc attcgatccg atgagaaggc
    75481 gtctcagtaa tttcattcgc tggtctcctc agaaaactga agcctgtaag gataatgggt
    75541 tttccgcttt tccacaggcg gcagaaccat gtaatcgccg tacatgcttc ggagcatctc
    75601 gtccagattg gccgggaagt tcagcatcct gccctcgaat tccagcttct gcaggggata
    75661 gcacttctcc ctgtccacca cgttccagta gggactggta tcgggcagga aggccatgcg
    75721 cctggtctgc tgctttcgat agcggcggca ggcctgctcg caccggaagc ggatgccctc
    75781 cggcttgatg gaaagcagca aaagtccctt gtgaaccatc ctgcagacag accagatgag
    75841 cttcgccttc atccccttct gcgccagagt cggttccggg atacttctta aaatcagaag
    75901 cttactgtaa aaccatgcct cccaggactg gatctggtac agaaccgggt tgtccgacac
    75961 gttgtccagc acatataagt ccagaaagat gccgaatgga cagtccacgt ccttcatcac
    76021 cttctccgca aacacagtcc ctctcttcac cagcctggtg gtcatcaagg gatagccagg
    76081 gtaattcttt ccgtttaaaa ccagatattt gtcccccatg gtcttctgga taatcttgat
    76141 aaatttgtcg aaatcatgcc gcggcatggc gatatcaatg tcatcgtccc aggggataaa
    76201 gcccttatgg cggacagctc cgatgcctgt gccggcaatt ccgaagtatt ccagatggta
    76261 tttatcacag actgccataa aatcgtccag gatcgataaa atctctccct gcagacgctt
    76321 aagcgtctcc ggctcataaa attccagatg ttccatacta tagttcctcc ttggcccgat
    76381 ccagagcgga gcggatcacc ttgtccatat cgtagtagcg gtactctgcc agacggcctc
    76441 cgaaaatcac ccgctcctcc ttctcggcca gcgctctgta cttctcgtaa agggcctggt
    76501 ttttctcgtc gttcaccgga tagtagggct ccatgccagg cttccagtta acgggatact
    76561 cccttgtgat aaccgtcttt tcctgagttc cgaattcaaa atgcttatgc tcgataatcc
    76621 ttgtgaacgg agtctccctg tctgtatagt ttaccacggc cactccctgg taattgtctg
    76681 tattcagagt ctccgtctca aagcgcaggc ttctgtactc cagatttccg aactgatatc
    76741 caaaatagcc gtcaatggtt cccgcgtaca caattcgttc agccgcgttc tcatactcct
    76801 gcctgtgttc cagatagtct acgccagtgc ggatctcgca gccctcaaac agccgttcaa
    76861 tcagagcgtt gtagccgtcc acaggtatgc cctgatacgg atcgttaaag taattattgt
    76921 cgtaggtata gcgcactgga aggcggcgga taataaatcc cggaagatct ctgcagtctc
    76981 ttccccactg cttttccgta tagcccttca ccagcttctc gtagatatcc gtgcccacca
    77041 ggctgatggc ctgctcctcc aggttcttcg gctcgccctg aatcacagac ctctgccgct
    77101 caatgatttc cctggcctcc tcaggagtgg agatattcca catcctgctg aaggtattca
    77161 tgttgaaagg catgttgtat atctgcccct tataattggc taccgggctg ttggtatacc
    77221 ggttaaactc tgtaaactgg ttgacaaagt cccatacctc ccggtcagaa gtatggaaaa
    77281 tgtgggcgcc gtagcggtgt acccggatcc cttccgtctc ctcgcagtaa atatttcctc
    77341 cgatgtgatc cctcttttcc agaaccaggc aggtcttccc ctgctttctg gccataaagg
    77401 cgaataccgc gcagtacaga ccgctcccca ccagaagata atcatattgt ttcattttac
    77461 ccagctcctt ctcttttcac gattttcacg attgttctat tttactatac ttgatccgga
    77521 aagtaaaggc aggaggaata gcccacgaac ttggaagatg cagaagagaa aagttttccc
    77581 tgctccacca aaagcttagt cgctggaaaa cttttctctc ctgcatggca gcactcatgg
    77641 caggcgggaa taagagattc tcctgttctg tagattatgc acgaggaaaa attttcggtg
    77701 actttaagtg gaacaagaaa atttttccct ctatcaggct gatgcctgcg ctgcaggaca
    77761 agggtgctga attggcgctc cgcagacgct cgaacagctg cgtcattctc cgatccagaa
    77821 tctccttatc tgtcacgtcc ttgacaaata ccagaaattc gtctcctccc agccttccaa
    77881 tcaaatcgtg gcttctgaag gtgcttctca aaatttctgc cagggatttc agcagttcgt
    77941 ctcccgtcag gtgtccgaac tgatcgttca ctttcttaaa atcatctaaa tccaggataa
    78001 tcagagttcc ttttctgtcc ttctcagagg tcatgaactc ccgcacctcg ctctcaaaaa
    78061 tcttgcggtt gtatacgtta gtcagaggat cccgtctgtc cgccctctcc tgagccatct
    78121 ctcttctctt ttccgcgtca atattcttca tgtacataag agcgtacatg ttttccgtat
    78181 agcggtcctg gaatacgtga aataccagct tcatccagca ctgctggccg tttaccatac
    78241 gtctgaagga catttcctgc gtcgcgattc catttttata catctctttt atgtaatgaa
    78301 gattaatgct gttttgatat gaatcccggt cctcctggca gacgacgcga tcgatctgcc
    78361 gcctgataat ctcgtcaaag gtgtagccct gctcctggtt ttccgccttg taatgctccc
    78421 aaagcccgcc tgactgcatg accttttcgc tctccacatc cacctccgcg taagctaccg
    78481 tctcggagag cagagcctca tagaagtccg tttttctcat gtactccagc tccatggctc
    78541 tctcctcgtc cgccagatcc atcagaaccg ctatggtata caaatcctcc gccttactgc
    78601 ttaaatgtct tgtttttacc ttaaaccact tatattctcc ttcctttacc cgaaacagca
    78661 tctctctgct gtccggatcc tcctttttat ggacatcccg gaacagctcc cggaactctc
    78721 cggcaaaatg aggatgcacc atctgcgtcc ggatccagct ctccgggaaa tcctcctccc
    78781 gcacctggct gccggccagc atggtcctgt ccgtgtgaaa ataaatagtt ctcttctttt
    78841 cattgtactc gaacatctcg ctcttcacgc cgtcaggcag aaagtcgggc cgctccagct
    78901 cgctgatgat cctgtgatag ccctccaggc agatctttcc ctccttgtcc gcagcccgga
    78961 ccgtcataca gcggactgtc acctcccctt tcgccgggtg gttccaggta tactctacct
    79021 ggataatctt tcctgtgctg atacagtttt ctaccgccat attaatgtag tgatagtagc
    79081 ctgcgttgat ccggctgtac cagtgggtgt agcactcctc cggcgtaata tcttctgtaa
    79141 tgcccataat cctgcgcatg accggatctg cgtacatctc gcctttctcg gtctccggat
    79201 ccagacggat ctcccagagc cccagattgg tattatctaa aatttccgcg tactgggagt
    79261 cgaacagaca gctccggcag taaccgctcc ggccaaactc tcccttttcc atcaggtagg
    79321 cctgtctctg atggtcgagg gtctcccact cttccatatt gatggccatc tccagccggg
    79381 ccttcctgcc ctgccaggaa atcagcctgt cctttaaaat ataccgggat ccgagaaacg
    79441 cattgtttct ctcccacacg tgaaatttgc ttttgcagag ctttccgttg gtgcagaact
    79501 cgcaggggtt ttccttgccc tggagaacct cgtagcattt tcttccctta taatcgtaaa
    79561 tgcctgtgat tttacggccc tgggcgttca tatagtacag ctcgtacgtt tccacatcgc
    79621 tgacgtaaat gatctcgtcc atgccctccg cgatggttcc aatctcctcc tggcggaggt
    79681 tttccagcat cctgtcctct gtatcggaat caaggcggcg cagcttcgcc tcccgcttct
    79741 cccgcttctg atactctttc gtctcctcgc agatataaat tcgctcaaat tcctcttttt
    79801 tatagggctt tgcaaagaga aagccctgaa gcacgtccgg cttcagctcc tttagcgcca
    79861 gaagctcctc ctccgtctcc acgccctcgc agcacacctt aattctggcg ctgtgagcca
    79921 gctcgatcat gttgctgagc agccggtaat tataggcatt atgctgaata cgactgacaa
    79981 agcagcgatc aatcttcgtc tcatccacct caatactctt tagatagctt aagctggaat
    80041 atcctgtccc gaaatcatca atggaaatct ggattccata ccgcttccac tcataaaaaa
    80101 tcttattaaa ataagaataa tcctgaagct gcatactctc cgtcacttcc agagtcagag
    80161 cctccccggg aagatccatc tgctgcagaa gagccagaac cgcttcctca attcccttct
    80221 ggcgcagctg gacataggag atattcacgc tgatatgaaa atccggaagc ttctttctcc
    80281 actctctgca ctggctgacc gccgtctgaa ggacccacat gccgacctca cagatcatgc
    80341 cgctctgctc cagcagaggg ataaactccc cgggccccac cattcccctg gacggggatt
    80401 catagcggag cagggcctcg gccccgtaaa gcctgtaatc gcggctgtcg atctgcggct
    80461 gatagcagag gtaaaaaccg ttgcagccat tgcggacaga ggccctcatc tcatcctgca
    80521 gcgcaatttt ctccagattt ttctgatagt cgtccgatga aaaaaatacc aatgtatttt
    80581 ttccctctct tttagcacgg tccagagcgt tctccgcata ctggtaaacc tgtcccccgt
    80641 ccatctcgtc tccgcagctg tagatcgcca ctccggcgga tatggtacag tatttttcca
    80701 tttctctctt taccaaatca tagaagtcca gaacgtcctc cctgtatttt cccggaaaat
    80761 tcacggcaaa gcagtctccg gccagacggt acagctgaag gggcgtttcc gaaagatttt
    80821 ccagtgtctc tgttatggtc tttaaaatat agtttccgaa tgtccttcca ttctttacgt
    80881 taatgctctt aaaattgtcg attcccagta ccatcaggta gccgccgctc tgtctgaggc
    80941 attctgtcat atcttccaga aacttatcgt agttccaaag ccccgtcagg ctgtccgtct
    81001 tctggcccac cgccagctca gaaatgcttc ccgccagaaa gaccgctttc ccccgtcgtc
    81061 cgtctgaacc tcgcttttgg cgttgatcca tacgcggtgt ccgtctctgt ctgtcagcct
    81121 gtaattcatg gcgtgtctgt cctttcgccc ttgggcgatt tcctcaatct ccttctgaag
    81181 ctgtctgcgg tctctgtggt gtacaatgcc ttcccagcac tctaagggaa ttccctcctc
    81241 tcccggaagc ggaaggggat atttcccgca tattttatct gcaatatgaa ttcttctgtt
    81301 cactaaatcc agcacataca ggtaatcatt agcgctctct gaaaaaaagc ggactgtctt
    81361 cttatataac tgcagttctt tatttacatc catacttatt tcctgccttt cttcacctct
    81421 ccattctatc atcctgaagg caatttctcc atgaaaattt tcagcagaaa cacaaaagaa
    81481 tcaaaaatct tctccctgaa aagccaaaaa aggacgcggc cagaatcaaa tagtttctgg
    81541 aacgcatcct ctcttctcaa ttctattttt tatggtgccg gctgggaaat ttgaaccggc
    81601 cggttcttcc tgtcccttaa ttttctgtgt agaacagacg gttcaccgcg ctgaaaatac
    81661 cgcggataga agctctcgta atattggagc tgattcccac gccgtaggta gtgcggccgc
    81721 tctttacatc taacaggtga atgtaggaag ctgcctgagc tccggaaccg gaacgcagcg
    81781 catgctctgt gtaatccaga acgcggatct ccacgcccag agtgtcctcc aggcctctct
    81841 gaatggcgtc gatcggtccg tttccaaccc cttcaaaccg cttctcctgt ccatgttctg
    81901 tataaatcac atctgccact gtagcgaact cgccctcgtc catctctctg tccgtaatct
    81961 ggcattttct gaagtgaacc ggctcctttc gctcgatgta attcttctgg aactctgcaa
    82021 agatctgctc cggatccacc tctccctggg cctccgcaat tttctgaatg atgtccgcaa
    82081 attccttgtg cattcccttt ggaagcttga agccgtagaa ggtatccatg acaaaggcca
    82141 cgccgccctt gccggactgg ctgttgatgc ggaccaccgg ctcgtattcc ctgccgatat
    82201 cgcttgggtc gataggcaga tagggaacct cccagatgcc gtccgttctc tttgaaaggg
    82261 cctgcattcc cttgctgata gcgtcctggt gagaaccgga aaatgctgta aataccagct
    82321 ttccagcata tggatggcgg ggatccaccg gcatcttggt acaccgctcg cagacgtcca
    82381 caatctctct gatattttca atctccagct ccggattaat tccctgggag aacatgttgt
    82441 aggcaatgtt taagatatcc acatttcccg tccgctcgcc gtttccaaga agcgttccct
    82501 ccactctctc agcgcctgct aaaagagcca gctctgtggc cgcgatcccg gttcctctgt
    82561 cattgtgggg atggatgctt aaaataatgc tgtccctgtc cttgaagtga tggttcatcc
    82621 actcaatctg atcggcatag acattgggcg tcgtcatctc cactgtggcc ggaagattga
    82681 taatcatctt cttctcaggg gtgggctgcc attcctcctg gacggcggtg cagatatcaa
    82741 gggcaaaatc cagctctgtg ccggtaaagc tctccggaga atactccagg atcacctccc
    82801 cgtcatgggc ctgcatatat ttcttcacca gcctcacgcc ctccacggca atctccttga
    82861 tctcctcccg ttccttgtgg aacaccacgt ctctctgcag cgtggaggta gagttataga
    82921 tgtggacaat ggccttcttc acgccctgaa tcgcctcgaa ggtgcggcgg atcaggtgtt
    82981 ctctgcactg tgtcagcacc tggactgtca catcgtcagg aatcatcctg cgctctacca
    83041 gctgtcttaa aaagtcgaac tcaatctggg aagcagccgg aaagccaatc tcaatctcct
    83101 taaagcccat cttcaccaga aggcggaaca tctccatctt ctcttccact accatgggct
    83161 cgatcaaagc ctggtttccg tctctcagat ccacgctgca ccagatcggc gccttctcaa
    83221 tctggcggcc cggccactgt ctctccggga aatccaccac aggaactctc ttgtatttct
    83281 tataattcag catatcattt tcctccaatt ctcaagcatt tccggttatt tcatctggtt
    83341 ctcactcaag ccttggagtc gataaaccac gccgtaattt ttcactatga aaatcgttat
    83401 cttttcaggt ctaaccccat gtccatcatt ccttttcttt ctaaaaatat ggtaacgaca
    83461 aaatgtttta gctgccaaag gcagcggcag atgtgcgaag cacagctgta ttttggagtt
    83521 attatatcat atccgccttt cagacttcaa ggctaagacc tattaccgga gagatctatt
    83581 tcacatggct tttataagat agggttatgg ctggaaaacg gctgatcaga ataagggcag
    83641 gccgcctctg cggtctgccc cctggtttac ttgcagctct cggaaagctc ctcatgcttc
    83701 tttaacagct ctactgtcag cggctccggg aaggtctttg ggtaagcgga gctgttctcc
    83761 ggattggtcg tctccccggc atagacggcg tttggataat agctctgaag ctccgaacgt
    83821 ccctttatga taatgcactc cgccatttcc tgggccagtg gattggtctt ttctccctta
    83881 tccacaactg ccacagactc tgtcagagag aagttgccct ctgtcggatc cacgaagtcg
    83941 atgggaagtc ccttggcctt gtcggctaca gcctgctggc ggagtccaaa gcccaccgcc
    84001 acctcgcctg ctcttacctt tttcagggga gcggagcctg aggtctcgat gtggggccct
    84061 gcgttttcat agatgcctgt gagagtttct ttggctccgt cctcgccgta agcgtccact
    84121 aaggcctgaa tcagaagcca cgcggtagaa gaactcttta cgtctgtgac ggagatcaaa
    84181 tctttatatt ccggttttgt caaatctttg aggctttccg gcatatccag atgattttcc
    84241 tttatcatct ccgtgttgac gatcatggtt ccctcctggg aggtgatggg agcgcagtaa
    84301 tccttctgct cctcctgatt taacagctca aaatcaaaat tcagcttctg aaacatctgc
    84361 tgtgtttcct gggcgctgtc aatgtagaag gtgctgaggg taatcagatc tgcttccatg
    84421 tccgtcccct ccgccatcac cttgccgccc agctcggagg tgccaaaggt ctggaagata
    84481 tattttccct catacccatt ctgatccaga gtctttttca tggcctccac cgcctcgtcg
    84541 tctgcgttgg agtaaatgac tacctcttcg tccttctggc ctcccggctg ggaacagccg
    84601 gtgagcgtca tgcctgataa agctgccgct gccgccagcg ccaaaactgc agtctgtcct
    84661 gtccttcttt ttgtttttgt ctcctttttt ctgaaccgca tacagattct cccttttatc
    84721 tttttatttt tattaatttg atttttttga attttcctgt ttatttcatt ctctttttca
    84781 gcgccgccag aagccctttc accgccaggt tggtgaacag aatcagaagg gacagcacaa
    84841 atacctcgtt aaacttcgtg taatactgca gctccttgat ttttgtggta atgaccatgg
    84901 ttctcgctcc tgcgatgaag ataaccgcgc tgacggttac catagcgttt acaaagtagt
    84961 atccgaatac ctccagaagc gtagaagcca tgtttggagt gataatccgc acaatggttt
    85021 taaaccagct gtctcccatg agagacgccg tggcctccca ggagctgttg agctttgaca
    85081 gcgaattttt catcatcaga tacggcgtcg aaaaaaagtg tacgatattg cagataataa
    85141 ttaaaatcag cgtattctga aggggcgtgc ctgtaaaaat aaacagaaac gcaataccaa
    85201 ccaccattcc gggaatagtg ttcgtcacca gcgcaatgcc gtcaatcacc gctttcagcc
    85261 tgctgttcag gccgcttctg gctgtggcaa gagccgatcc gtaggtgacc agaagtccgc
    85321 ccgccgcagt gcagacagcc acaaaaagtg aattttgata cacatccgtc aggcttctgt
    85381 ccgtcagcgt ggagattacg tgctccaggg tgaaggaagt ctgataaggc cattcgctga
    85441 ccaggggaac cacgaaaatc acggcgaaga cagagagaag ccccagcagg aacaccgagg
    85501 atcctgcaaa gaaaactccg tcccgaagcc tgttttttct gatttccacg gtggaaatct
    85561 tcgagtacct gatgttgtac ttttccagcc agcgcagcag ggcgatgctg actgctgacg
    85621 gtatcagcat catcatggcc accacggctc ctctgttaaa atccggcacg cttcccagca
    85681 tttcattgta gagaaccgtg gccaccacat cgtacctgcc tcccacagac gccggaattc
    85741 cataatccgt aaagcacagg aaaaagcact gtaccatgga agctgccagc gttcccagca
    85801 gaggccttgc cacggtctgc agaaaggttt ttaaaggctt atcacccatc accctcgaca
    85861 ccacggaaaa tttcttgtca atgtagcgca tggtattgag aatcagcagg aacgacaccg
    85921 gaagagtgta aatcacatat ccgaacagca gtcctccaaa gccgtaaatt tcaaatatct
    85981 ggcgcccaaa cagtctggtg agaagcccct gttttccgaa ggaatagata atggcaaagc
    86041 cgtatgtaat cgtcggaagc agcatgggca gcgtcgccag agtgcggatc aggctcttaa
    86101 agactggggg cacgttagtg tattgaatgg tataggccag aaaaaaggcg atggcggtag
    86161 ctgtcaccgc gctggcaatg gacaccgccg cgctgtgtcc cagcgccgtc agaaatccct
    86221 tcccggtcag cacgctgata taatttgcga ttcccgctcc cgcttctgac gcaaaggatt
    86281 ccgctaaaag cctcagcacc ggaacggcca gaaaaaaagc gaagaccgcc accacggcgc
    86341 agtaaatggt ttttatctcg tattcttttc tgccagtcat tctacaccgc ctgttccctt
    86401 acgcagactt cagcccctgc gcccgcttcc tgaaagctgc gatccagact gtccaccgtt
    86461 ctgttgaaga ggcggaaaat attttttctc ttaatttcca gctggtttaa aataaaatcc
    86521 ttcacaaact gattacccgg ctggaacaca atctcctccg gcgttccata ctgggaaatg
    86581 ccgccctgat tgacaatcag cactttgtct gacagcgtca gcgcttcctc cggatcgtgg
    86641 gtaacaataa tcgtcgtcag atggtagtct ctggcgatct ggcggatttt ttctttgatg
    86701 gactccttga tcactccgtc cagagcgctc agcggctcgt ccagcagaag aatcttgggc
    86761 ttcattacca tcgttctggc aagagccgct ctctgcttct gaccgcctga cagctgctca
    86821 atcttctttg ccaggtgttc ccgcagtccc agcagatcaa tcagctcctc cacctcctgc
    86881 ttcgtggaaa ttcccggacg gtttttcagg ccgtaggtaa tattctgata tacgttcagg
    86941 ttaggaaaca gggcgtaatc ctgaaatacg atattaaatc ctcttttctc catgggaagt
    87001 ctcgtcatct cctgtccgtc aaacagaatc tgcccctcgt ccgcatccgt cagtcccagg
    87061 atcagattta acaaagtggt ctttccgcat ccggacggcc ccagaatgga cacaatctca
    87121 ccatcctgaa tctccaaatt gatatcgctc agaatcgtaa ctccgtcata agattttttt
    87181 atatgtttca gctccagcat aacagcattc tcctttcacg gcgttttctc aaacgcctcc
    87241 tgtacactga cgctattata actggacgca aaactgggaa ctatcatggt tttgaaaaat
    87301 tttgtaagat cagattaaag aagtggatat gtctgtaaaa tgtcttaaga agaaggagga
    87361 gcagaaatca ttctgtcccc cctctgcaaa aatattctgt tttccgttct ctctattgat
    87421 atttccgctt tattccatta cgcgttttct gcggccagct ggtactcttc tatcagctct
    87481 ctcatatgct ctgcattttt cactaagatc acctggtcgt ctactgccag gcagggaatt
    87541 ccggcctgat gcttctctct ggcctccctg tgggcctccg aggtatcgcg aaccctcaga
    87601 aagctcttca gtctgcctac gctctcgcag atatccacgt agagatactg cacgttactc
    87661 tgggaaagaa cctctttcac cggcggacag tccggtcagg aggctgttcc aaataaaata
    87721 atttttctca tccttgcgtt ctccttcaca ttttccctct atttttccct ctatctttcc
    87781 ttctatcttt ccctctgctt tgcccctctg ctttccctcc tctatctcct ctgcaaacag
    87841 ttctcttaat gcattgcaca tatgcttcgc ctcctcatac tgcttagcca gaccttctcc
    87901 ttccagtata atcaaatttt catatttcag caatgtgatc ttaacttagg caaaaacagc
    87961 aggttgggcg ataacagcga ggctttcgca gggaggttcg tgctaatttc cgccatcgag
    88021 caaaatgtct gagccgtaag gcgagttttt gcgaatggcg gataacggat gcacgaaccg
    88081 agcagaaaac gcagctagtc gcaaatcctg ctgtttttgt ctgttttgca ataacttaag
    88141 aaaagggagt atattcctgc gtttatcatg acggcaatct taacagcact gcaaaaaaga
    88201 gaaaacgttt tccagcgcct ttatctgcgc tctgaaaacg tctcctctct ttttctctta
    88261 ttcctccgtg tgcactgcag aggctgtcag ttttccgttc tgctcgtcaa tctggatcac
    88321 gtccccggca cgcacgccgt cggccagaat cagtctggct gccagcgtct ccacgtgctt
    88381 ctgcagatac cgcttcagcg gccttgcgcc gtaaaccggg tcgtagccgt tctctacaat
    88441 gaactgcttt gcgctgtcag tgagagcgat ggacagctct ctgtcggcca gacgcttatt
    88501 cacatcctcc accagaaggc cgataatgcc tccgatattg ccctttgtca gcggcttgaa
    88561 catgataatc tcgtccagac ggtttaagaa ctccggcctg aaatgcgccc gcaggtcgtt
    88621 catggccata ttgtcagctg cctccgtgat atttccatcc tcatcgatgc cctctaacag
    88681 gtactgggaa ccaatattgg aggtcataat caggatcgtg ttcttgaaat ccacggtttt
    88741 tcctgtggaa tctgtgatcc ggccgtcgtc cagcacctgg agcagtacgt tgaatacatc
    88801 cgggtgggcc ttctccacct catcaaagag gacaacggaa taaggctttc ttctgactgc
    88861 ctctgtcagc tggccgccct cgtcgtagcc tacatatcct ggcggtgctc cgatgagtct
    88921 tgatacagaa tgcttttcca tatattcgct catatcgatc cgcaccatac tgttctcatc
    88981 gtcgaacaga ctctccgcca gagccttggc aagctctgtc tttcccactc ctgtaggtcc
    89041 caaaaacagg aaggatccaa tgggtttgga aggatccttg atgcctgcct tggagcggat
    89101 aatggcctcc gtcaccttgg tcaccgcctc atcctgtccg atgactctcc ggtggagaat
    89161 gtcgtccatg tgaagggttt tgctcctctc gctctccgtc agcttggcga ccgggatgcc
    89221 cgtccatttg gagataattc tggcaatctc ctcctctgtc acgctctcgt gaaccagact
    89281 cagatcctta tttttaactc tctcttcctc ctcagccagc tgttttttca actccggcag
    89341 ctttccgtac tgaagctctg cggccttgtt caggtcatat cgctgctggg cggcctggat
    89401 ctcgccgttt aaatgctcaa tctcttccct cagctttgac agcttatcca cagaagcctt
    89461 ctcattttcc cactgggcct tctgtgcggc aaattcgtct ctcagctccg ccagctcctt
    89521 ctgaagatct gccagacgat cctggctcag gcgatccgtt tccttcttaa gggccgcctc
    89581 ctcgatctcc agctgcataa tacgccttgc cttctcatcc agctctgtgg gcaaggaatc
    89641 cagctccgtc ttaatcatgg cgcaggcttc gtccaccagg tcgatagcct tatccggcag
    89701 aaaacggtcg gaaatatacc ggtcggacag cacagccgcc gaaaccaggg cggagtctgt
    89761 gatcttcact ccgtggtaca cctcatagcg atcctttaaa cctcttaaaa tagagatggt
    89821 atcctccacc gtcggctcgt ctacatgaac cggctggaat cttctctcca gagccggatc
    89881 cttttctata tattttctgt actcatccag cgtggtcgcg ccgatacagt gaagctctcc
    89941 tctggccagc ataggcttta acatatttcc ggcgtccatg gatccttccg tctttccggc
    90001 tcccacaatg gtgtgaagct cgtcgataaa caggataatc tgtccctcgc tcttcttcac
    90061 ttcctcaagc actgccttta aacgctcctc aaactcgcct ctgtacttgg ctccggccac
    90121 cagagcgccc atatccaggg cgaacagctt cttatccttc agcccctccg gcacgtcgcc
    90181 ccggacaatc ctctgggcca gtccctctac gaccgccgtc tttccgacac caggctcgcc
    90241 gatgagaacc ggattatttt tcgtctttct ggacagaatc cgaaccacat ttctgatttc
    90301 tccgtccctg ccaatcacag gatccagctt ctgttctctg gcccgctcta ccagatcgta
    90361 gccatacttg gacagggtgt cataggtggc ctccggattg tcgctgacca ctctctgatt
    90421 tccccgcacg gtggagagag cctggagaaa tccctctctt gtaatattgt aaagcttaaa
    90481 cagctccttc accgcacggt tcggctgctt caccatagat aagaacaggt gctccacaga
    90541 aacgtactcg tctcccatag atttcgcctc atcctccgcg ctcaccagaa ccttgttggc
    90601 atcctggctg aaatatacct ggccgccgga caccttcgga agcttttcaa tggccccctg
    90661 cacctcgttc agaaactgat tttcctgcac tcccatcttg gtgagcagct tgagaatcag
    90721 actgtcatca atcgtcagca ggctgtacag caggtgctcc tggtcaatct gctgatttcc
    90781 gtattcatat gccagcttct ccgtcctctg gactgcttcc agagacttct gagtgaattt
    90841 attaatgttc ataaatcgtt gtcctccttc cgaacaatga ttaagtaaga attctttttg
    90901 ttctagctgt aatataacac ttatcgttag cagtgtcaag agtcaagtgc taattttatt
    90961 taaaattttg ctcgccaaaa caagatggtc tttattggag attatctatc tattgatatt
    91021 atgtcacagc tgctgcatta atataggtag agttcggtaa aattcctttc ttttgtctat
    91081 tctacaatat atttcttgta catttccccc tttttttact gttggacatt gttataaaac
    91141 catggtattc tggcttcatc aattttacgt ttaagcgtac tgcagtgctg aaaaacgaaa
    91201 gaaaaaggag gggatattta gtgggaattg ttgcattcct tgtttatatt attttcgtta
    91261 tgatctggta tctgatgtta aagcgcagca tcgccgaggc aatgctttta ggcctcgtaa
    91321 tcgtatgcgc ctttaacgga gtcgacgtgc ttcctcagac ttttgccagc agcctgacaa
    91381 aagcgctgac gcaggacgtt atggccgcca tcattctgtt cactgtaatg gcttctatta
    91441 tgactcagac tggtattatc acccgtcttg tcagcatttt aaactctatc ctgggacggt
    91501 tccgcggagg tcctgcctac gtgtcagcct gtgccagcgc catgttcggc atggtatccg
    91561 gcgccagcag cgccaacgcc gctactgttg gttctatcac aatcccgtgg atgacggaat
    91621 ccggctggcc taaggaagtg gccgcgacca tgaatacagg aaacgccggc ctgggcatct
    91681 gcattccgcc gtcttcttcc atgttcctga tgctgggact tcccgttgtg gctggatctg
    91741 tggctgccgg cgatctctac atcgcgctga tgtgcggcgg tctctggagt cttgcttacc
    91801 gtctgctcct caccagatac tatgtgagca aatacaacat tcctgcagtt ccgaaggacc
    91861 gcatcgtgtc cctttcctct gccctgaagg agggcggaac ctctctgacc atgttcttag
    91921 gaattatcgt tcctctggta gtaatcacag gaccggtcgg aaacttttta aagactcttc
    91981 ccgccttcgg cgaggacggc gtcgacgcta tgaacatcat tatctgggtg ccggtgctca
    92041 tcatgttcat ctgcatcata gagggaagaa agctgcttcc gaaaactgcc tccggctggg
    92101 gaaagcttct ctcctccact gcaaagacct gctgctcctg cggagccgtt tccctctttg
    92161 ccatggccgg aagcaacgct ttaactgcca ctggcttcgg agacgattta acagcccttc
    92221 tgtccgctat ggatatgccg aagtttctca tgatcctgat catcggcttc gtcatcgccc
    92281 tggtagcagg tccgttgaac gctacctcca ctacagtcag cctgggacct gtggcctact
    92341 ccgccatggt cgctgtggga gtttctcctg tcaccgcaat cgtcagcttc ctaatttttg
    92401 cctccacaga gggagcttcc ccgccaatgt cctcccctat cttcgtgtcc agcagtattg
    92461 ccggcgtgga ggacgtcagc gttatgttta aggctctgat tttccactat gtcattccga
    92521 ttgttctggt aggcgctctc atcgccatgg gattcctgcc gattatagga ggttaagcca
    92581 tgaaaaagct gttaaattac ctgtttatcg cctgcgctgc ccttgctctt ctgctggcct
    92641 tcggctatgt ggcagttgag atggcggcgg ttatcaccgg aaacggcagt ctcaccatct
    92701 gggcggaaag ccacctggaa gcgcctgtct gcatcatgtg ctccctgaca gccatcgtat
    92761 cctttatcat gagctacgta ttccgctgga cctccggcga ctaaattttc attatccaaa
    92821 atgccggtga atggatcggg agtaattctg gaacaccatg cctgcatccc ggataaaatc
    92881 tcttgcatac tcaggaagtg gataatcctt ccgatacacc agggaaaccg tattttccgg
    92941 aatttcattg ataaccggaa aaacatgaaa cggtttccct gtttttcttt gggcatggta
    93001 attcttccag cagaccaccg gagacagaag gcccgctccg ctcccctttc tggccatatc
    93061 gtaaatcagt tcctgctcgt cgcactcaaa aatatactgc gggaggcggc aggaggaaaa
    93121 gaacgcgtcg attccctttc tcagcctgtt tccctggcgc acagtgatga agggcaggcg
    93181 gagcagccgt ttcaaatctg ccccctgctt aaagtcaccc aggatctgct cccactcctc
    93241 cggataatag gttttcaaaa gctcctctga aaagcagcac tgcacctttt ctttcgtcag
    93301 ctcatagatt tttctgtttg cgttctccac cacgtccacg ccgatatata aatcaatttt
    93361 tccagactga agcagatctt caaaggtatt gctgtttcca tggatcagct cgatggaaat
    93421 attgggatgg gaggcgtggt aaaaatccca gatcaccgga aaaaaggttt ttcccctcag
    93481 cctggaaatc cccagcctca gagttcctct gtgattcttg ctgatatcgg aaaaggctcc
    93541 ccgcatattg gcctccgcct ggatgatctg tcttccgtaa aacgccatct gctctccgaa
    93601 catagtcagg cgcagagaag gacgccgctc aaacagtgga accccgtact cgtcctccag
    93661 ccgcttcaag tggctgctca gcgcctgctg gctgataaac agccgttccg ccgctcttgt
    93721 gatattcatc tcctctgccg ccgccagaaa atattcaata cttttcaggt tcatttgttc
    93781 ctccttccac aatgtattca ttgttttttt tatcaaaata tagtgttaga cattgttata
    93841 ctggaatgtt atcataaatt cagttaaaag aaaagaaaaa aggagaaatc aaatggatca
    93901 gcttacatta atggactgca ccttaagaga cggcggaaac gtagtgggca agggatttcc
    93961 agccgatatt acagatatgg tattagacgg actgaccgcc tgccatgtgt cgattattga
    94021 gcttggaaat tccggcggta tcggagctta tgaagtagcc ggatttacag acgccttaac
    94081 agatatggaa tacctggaaa tcgccaagaa gtacatgaac cgcggttctg agctgggtat
    94141 gttcttaaac gcaaagcgct accgcgagaa aaatgtggat ctggctgctg agcacggtct
    94201 gtccttcctc cgcgtaggag ccgacgctgg agacggagac attgccctga cagctatcgc
    94261 tgacatgaaa aagagaaatc tgaaggcatt ctattctgcc atgaaggctt accttctgac
    94321 tccggccgaa ttagccgagg aggctaagaa gctggaagcg gcaggccttg acgagtacac
    94381 cattatggac tccgccggaa ccatgcttcc tgatcaggcg gccgcctaca cagaggcgct
    94441 ggcagacgct ctgtccatcc cggttgcctt ccactgccac aacaacctgg gactctccgc
    94501 agccaacgct ctggcagcag cccagaacgg agcaaaaatc ttagactgcg gtctgatggg
    94561 aatggccaga agcgccggaa acctgcctac agaggtatgc gtagctatga tgcagcgcca
    94621 cggacagatg atggacgtag atctcttcgg tatgctggac ttcattgaga accgcctgca
    94681 gccggctatg gaaactcaca actaccacaa tcctatcacg ccgaccgacc tgactctggg
    94741 cttctccgga tgccactcca gcttcttaaa gctgttccgt cagacagcca ctgaaaagaa
    94801 ggtcaacctg ttccgcctga tcacagaggt atctgccgtc aaccagaaaa atccttctgc
    94861 acagctgatt gaggaaacgg cagaccgtct tctgagcgaa taatcagagc agaaatcatt
    94921 cggagggaaa ttatcatgaa aaaagtaatt cttgcgggaa cctatcccgc tcataccttt
    94981 gaaaagcttc gggctatgct gccggaagag gagttcgagc tgaaggcggt ggacacgccg
    95041 gaggcctacg acgccatgac agacgctgaa tttatgattc tccgtatttt taaggcgccg
    95101 cgtccagtca ttgagcgcaa tccgaatctg aaaatgattc tccgctgggg cgcaggcttc
    95161 gattctgtgg acatccaggc agccggagag cacggcgtat gcgtcacaaa cactccggga
    95221 gccaacgccg gagccgtttc cgagctggcc gttctcctga tgttagccgt aggacgcaag
    95281 cttctgtgcc acacagagag cctcgccaag ggagagtgga gcaaaaatac atttttaaac
    95341 ggttccttct gcctgaacgg caaaactctt ggcgttatcg gagccggaaa tatcggccgt
    95401 caggtagcga gaaaggccca ggccttcggc gcagtgacaa actactacga tcccttccgc
    95461 ctctctccgg agatggaagc agagtatcac ctctcctacc ttccgctgaa ggagctgctt
    95521 gcttcctccg atctgatcac gctgcacgtg ccgctgacag aggaaaaccg ccatatgatc
    95581 ggagcagagg agattgcttc catgaaggat cacgcaatcc ttatcaatac ctcccggggc
    95641 ggtctggtag acgacaaggc gctggctgag gccgtagcct ccggaaagct cttaggagcc
    95701 ggtctggacg tggtggagga ggagcctctt cctgccggac atccgctcct cacaaacccg
    95761 aatatcgttg taactcctca catcggaggc ggtacagccg atatcggaga cgtaattatg
    95821 cctatgctgg cagaggacat taagacaatg gctgccggaa accttccaat ccatactgta
    95881 aataaagaat acttaaacaa ataagcaaag agactgaaaa gcgcctggga gacaaaataa
    95941 aaagtctccc aggcgttttt cagtctcttt atttatgccg gctgtcttct ttcctctcct
    96001 ccaccagaaa ccctctctgg cggagcattt cctcgatggc gtccagagtc tcccggctgt
    96061 ccgcactgac tgtgtggtag tggtagcctg atgtgatact gctcagaggg ctggagctcc
    96121 catgtttgat gtcctccaga aagagggcga tcttccgcct cgagctgata tttaactccg
    96181 cctccatgcg gccgtaaatc ctgtgattca ccgccacgtc cttcacacag ccgcccatat
    96241 ccacgatggc gttcagttcc tcctccatct gctcgttcgt gtggcgcacc ttgaataccc
    96301 gctccacctg gcttaaactg ttcagaatgt agcctctatt ggtagaaata atgtcgtagc
    96361 ctgcggcccg aagaagggcg atatcctgga caatcacctg gcggctgacc ttgcaggacg
    96421 ccgccagact ccgggccggc accggagaag ggctcttctg aatgattttt acaatctcgt
    96481 ttcttctatc tgttccagtc accgactgca cctcctgctt ccattcccgg agctgttttc
    96541 ccgccgtttt cctatactgt gggctgctct accggatgca gatgctttaa ggaaatgtcg
    96601 agaatcggag cggagtgggt gagggcgccg ctggaaatat agtccacgcc gcagtcgata
    96661 tagcgggcga tattttcctt tgtcacgttt ccggagcatt ctgtctccgc ccttccgtca
    96721 atcagctgaa ccgccttctt catatcctcc ggagacatgt tgtccagcat aataatgtcg
    96781 gctcccgcct ccactgcctc cttcaccatg tcgaggtttt ccacctccac ctcaatccgg
    96841 cgcacaaaag gagcgtactc tttggccatg cggactgcgt tggccactcc gcctgccgct
    96901 ccgatgtgat tgtcctttaa cataacgccg tcggacaggt tgtagcggtg attgtggccg
    96961 cctcctgccc gcaccgcgta tttctcaaaa atacgcatgt tcggcgtcgt ctttctggtg
    97021 tctaacagct ttaccttgct tccctttaaa agctctgcca cagagtgggt gtaggtggcg
    97081 attccgctca ttctctgcag ataatttaac gccaccctct ctccagaaag gagaacccgg
    97141 atgtctcctg tcagctttcc catcagctgt ccggccttta cctcgtctcc gtctgcacag
    97201 aaaaattcgc actctgtggc cgggtccaga agctcaaata cccgcttaaa cacatccagg
    97261 cctgcaatga ttccgtcttc cttgcacagc agatctaccg ttcccttcac tgcctgcttc
    97321 atcacggaat tggtgctcac gtcctcgctc gatatatcct ccttcagggc ctccataatc
    97381 agatgatccg cctgaagctt cattgtaatt gaattaaaca tacccctgtt ctccttctat
    97441 ctgcaactat tcctatcatg ttcctcgttt actgctctcc cagcttccgt ttcatgtcgc
    97501 ctgcggctct cttggcgaac acaaggctct ccagcaggga attgctggcc agacggttgg
    97561 ctccgtggac gccgttgcag ctggtctccc ccactgcgta gaggcggtcc atggtggtcc
    97621 ggctctcaga atccacccag attcctccca taaagtagtg ctgggccgga accaccggaa
    97681 tccactcctt cgtcacatcg tagccctcct ccaggcaccg ctgacagata ttggggaaat
    97741 ggcttaaaat cgtttccttt ggaatcggct ctaaagacag ccatacatga tctgtgccgt
    97801 ctgcctccat ctgctttctg atagcatttg tcaccacgtc tctggggaga agctcgtcca
    97861 caaaccgctc tcctttctta ttgtaaagaa gcgccccctc tcctctcact gactccgaaa
    97921 tcaggaatct ccgtcccggc ttttcagagt agagagtcgt cggatggatc tgaacataat
    97981 ccaggtgctc taagcggatg ccgtgctttt cggccactgt cagggcgtct cccgtcaggt
    98041 gggggtaatt ggtggaatgc ttataccgtc cgccgattcc tccgctggca aataccgtaa
    98101 actctgcccg gatctccaga agctcgtccc cgcatctggc tgtaatgcct gcgcatctgc
    98161 cgttttcctc aatgatatcc gtcatctcgg taaactcccg gatctccaca ttgggacact
    98221 ttctcactgc cgccaggagc ttggaggtaa tctcctttcc cgtaatgtcc tcgtggtaga
    98281 gaatcctggg cctggagtgg gcgccctctc tggtgtaggc cagctctccg tcctgcttct
    98341 caaactccac gccaaagccg atgagatcct ctataatctc cctggagctg cggatcataa
    98401 tgtccaccga ctccttccgg ttctcataat ggcccgctct catggtgtcc tcaaagtagc
    98461 tgtcgtaatc ctcgtcgtct ctcagaacac agattcctcc ctgtgccaga aatgaatcgc
    98521 tgctctccgc atcggatttc gtaatcatgg taatgcgccg gtccctcggc aggttcagcg
    98581 ccgcaaacag gccggatact ccggttccta caatcactat gtctgtctct gtcttcatgt
    98641 ctcctcctaa gccctccggg ggcccttctc aaatctatcc cgccggcaaa atctgccagt
    98701 tcctgtccgc ccttttccta tttggccaga cggagcattt cctctaaagg ctttcctgcc
    98761 tcctccacca tggacggatc tgccagaacc tcattttccc ctgtctccag tacgcggaga
    98821 atcttttcca gagtaatcag cttcatatcg ccgcagacag gctctgtagc cgtaaagtag
    98881 aacttctttc caggacagcg ctttcctaat tcgaagcgga caccgttttc cgtacaaatg
    98941 ataaactcct tcgcgccgct tgcctccgcg tgggcaatga tgccggaggt gcttccaatg
    99001 tagtcagact ctctgcagac agcctcgccg cactccggat gagtcagcac ctctgcctct
    99061 gggtgctgtt ccttcagagc ctgaagctcc ttaagcttca actcctcgtg aaccgggcag
    99121 aagccctcgt taaatacgaa atgcttctcc ggcgcctgct ctgccacaaa gcgggccaga
    99181 tttctgtccg gaataaagaa aatgtttttg ttaggcagag cttttacgat tttcaccgcg
    99241 ttggcggagg tcacgcacac gtctgaatga cgctttaact cggctgtgga gttgatgtag
    99301 cagacaacgg ccaggtcgtc ccaggttttc cgcatctgtt caatagtctc cacggaagcc
    99361 atgtgggcca tggcacagtc tgcggacgcg tccggaagaa gcacggtttt ctccgggttc
    99421 agaatcttta cgctctctcc cataaaagaa actccgcaca tcacaatcgt ctgtgcctca
    99481 agtccgaccg ccagcttgct caggtaaaag gaatcgccga tgtagtcggc aatctcctgc
    99541 acctccgggc gcacatagta gtgggccagg agcaccgcgt tcttctcctc cttcagccgt
    99601 ttaatctcct ctgcaatatt tcttgtcata tctatctcct tctctttgct gttcatctgt
    99661 cttaagcgca attgtggcta ttatactacc agactttaca tatgacaaga cagttgtata
    99721 tttttgatat tttcttaaca atctttatcc tctaagcagt tacagagcga tccccgctgg
    99781 cacctcctcc gcctccacgg cctttaaaaa ggcctggtcg tgctccacca gaagcatggt
    99841 cagacgattg ctgcggatca cctcctcgat ctgcatccgt gagaacacgt cgatgtagtt
    99901 gagcggttcg tcccacacgt agacatgggc ctgctggcag aggctttttg ccagaagaac
    99961 cttctttttc tgcccctcgc tgtactgctc cataggctta tgaaacagct ctctgggaat
   100021 gtccagcttt ctgagaacag tcaaaaacag ggaacgatcc acctcctgct ctctggcaaa
   100081 tgccgtcaga tctcctttca gaaaggaagc gtcctggggc acataggaga ttttaaggtc
   100141 tgacggcaga gagagctccc cgcttaaccg gatcagacca catgcgcctc tctccggacc
   100201 gtctgcctgt gcctccttaa aagcctcctg cgtctcctga gcggcagttt tcaggatttc
   100261 ccggatgacg gaagattttc cgctcccgtt tcctcctgtc aatgcaatgc gctgtccctg
   100321 ttccaggaca aagctgagcc cctgtccctt cttccgggcc gaaaggccag atcctgcctc
   100381 ctctcccggc tggtaagaaa gcctcagatc ccgtacgcgg atcagttcct ttttccagtg
   100441 agtcagaggc agtatcttta agggctgttc ctcctccaca tcccttaaaa gcttctcctt
   100501 ttcctggatc gcccgctcct ggcgctgttc cagattcttc ctcctctgct gcatttttct
   100561 ggatttttca cccagatagc ttctggttcc aatgaatttt cctcccacaa aggatccggt
   100621 tccgattttc attccctctg atcggtctgc ccaggcgcag gcggcagcgg cggaagcctg
   100681 gagacgcccg atctcctttt tcagcttctc gttctcctgc cgctcaaagg cgtcccggcg
   100741 gtccctgttc tcacgccagg cagaaaaatt cccctgcaca atctcaacgc tctcccggtt
   100801 cagagccatc acatggtcaa tgcacccgtc taaaaagctt ctgtcgtggg ataccagaat
   100861 gaatcccttc ttcctgttta aataccggct gacaagccgc ctgccctctg cgtccaggtg
   100921 gttggtgggc tcgtcaatca aaagaaatct tccctcgcgg cagaaaagag ccgctaaaag
   100981 agccttcgtc tgttctcctc tgctcaggga cgaaaagggg cgaaacagcg tctcctcccg
   101041 aagctccagc agattcatct cccgcagaag catccagaat tccccgtccg gacagacctc
   101101 atccagaacg tctatggtat ttttatcagg atccggaaca tgatatggaa aatattcaaa
   101161 gggctcggag gacaaaatcc tgccctcgta ttcgtattcc cccataaaaa gccttaaaag
   101221 cgttgtcttt ccttttccgt ttctccctac aagccccagc ttccagtccg tacctatgga
   101281 aaacgacata tctgtaaaca cgtcctcccc gccgtcatag cggaaggata aattttttgc
   101341 ctgtatctgc gccatcgctc attcctcctc tcagtgttca ggccggcaga gcgtttttat
   101401 ttcaccaggc gtcatcttcc tgtgaaacaa aaaaaggatg cagaaaatct tctgcatccc
   101461 ttccatgaat actgatatct gaggtctatg ccgcctgcat cagcccttcg gcttttgttt
   101521 tccggcttca gccccgcctg caatctcaaa acaggcgccg gaaacagcgg tttaccagct
   101581 tcatatgata ttgaatcgac gaaaagaatt ccgtatttct gctctgccaa aaagcggacg
   101641 ctgccgtctg ccttctatgc cttcattcaa ttgaattatc tgcagaaata catcttcatc
   101701 ctttcatctc ccatctgtct gtttttatga atccgcaaat ccatactgtt tcaatatatc
   101761 aacagttctt aaaaatgtca atcattttgt gggatttcgt gttccggctt ccgctctcaa
   101821 tcagcggatc agctccgcct ctttcacgct ctcgtcgccg cctgggcagg agtagtaaac
   101881 ggtcagctga tctccggctt ccggctcctt ctctgtctct gacagctcat ggcctctggc
   101941 cacagatatc ttctctccgt cctctgtctc gatgacaacc gcctctgaag ttacctcaga
   102001 tacggttcct gagacgcttc cggctgtgag agtgctgtcg ctgtcacggc tctctctcac
   102061 cagaatcacc tctgtcttcg tcgtgtcctc tccgtccgtc tccccggtgt aaaacagggt
   102121 aacattcata tctaaggtta agccctcgga aaagctggat gcagaatttt ccttggagaa
   102181 aatcagtccc tggggatact cttcattctg aatcactatg gagttcatgg cggcgtccaa
   102241 taccgttcct gtcatcacgg aaactgcccc gctctgattc tcctcttcca ggctttctgt
   102301 ctcctctgcc tgtgaagcgc tctcctctgt ctggctgact gtgctctccg gcgcagaaat
   102361 ttcctgcgcc tccttctgcc cacatcctga cgccagggct gctaccgatg ctgccagaag
   102421 aacagccgct gccatttttc ccgtcttttt catatgattg cctccttttc ctctaaactc
   102481 actctaaaac cgtccgaagg tgtccactaa aaaggccaga tagcctgttt cactgtctcc
   102541 aaaggccccc ggcttcatcc tccatttcca gtttccccct acggttcccg gcgtattcat
   102601 cctggcgtcg ttgtccagct ttaatacgtc ctgcatctgg aaaatggcca cgctggccac
   102661 agatccgtag gcagcccgga acacgcggtc cggaacctct tccctgtggg ccgcgcccag
   102721 atagtccgca atgtactgaa gctcccacca ctgccgcttc tccggcttaa aatacccgat
   102781 cagcgtctcg ttgtcatggg ttcccccgta aaccacggaa ttaggctcgt agcagtgggg
   102841 caggtgctcg ttaaaccggt ctccgctgaa ggcaaactca atgatcttca tgcccgggta
   102901 accggtcttc tgcagaagct cctttacctc cggacagaaa acgcccagat cctcggcaat
   102961 gattttcgtc ttaccggccg cctcattgac agccttcgta agcttctctc caggcccctt
   103021 tctccactct cccgtccttc cgtcctcagc gccataggga atggaataat actgcaccac
   103081 tccgatgaaa tgatcgattc tcaccacatc gtacagcctg gccgcagcct tcatcctgtc
   103141 tctccaccag gcgaaatccg tcttctccag agagttccag tcatagaggg gatttcccca
   103201 cagctgccct gtctctgaaa acgcgtccgg cggcactccc gccaccttta acggctttaa
   103261 ggtctccgga tccagctgga acagctccgg gtgcacccac acatccgcgc tgtctaaggc
   103321 cacgtaaatg gggatatctc cgataatctg aatgcccttt tcatttacat aggccctcag
   103381 cttatcccac tgcccgtaaa acttaaactg caggaatttc cagtagtcca tctcctctga
   103441 aagctctgct ttgtatgccg ctacggcttc cggctctctg cggcggatag gctcctccca
   103501 gttcagccat tcctcctggt taaaatggcc cttcagcgcc atgtacaggg cgtagtcctc
   103561 cagccagccg ctgttctcct ggcagaacgt ctcgtactcc tttgtctccc tgaagcggct
   103621 ccgctcgaaa gcttttttaa ggagcgggaa ccggtaatag cagactgcgt catacttgac
   103681 ctcgtcctcc ctgtcgcacc agtaacagga ctcgatctcc tcctttgtca gaagtccctc
   103741 ctccttcaga acgtctaaat caataaaata cggattgccc gcaaaggcgg aaaaggactg
   103801 gtaggggctg tccccatagc tggtaggccc caggggaagc acctgccagt agctctgtct
   103861 ggcctttaca agcttatctg caaattcata ggcgcaggct ccaaaggttc cgatgccgta
   103921 gggcgacgga aggctggaaa caggcattaa aatacctgcg cctctcttca acatggtctt
   103981 tgccatcgca atgcctcctg ttctgtctat tctttgaaga aaaggaaacg cagattaaag
   104041 caggtggaag tgaaccgcct gactgaccgg ctgcgttttc gattcaggcg gttcatttcc
   104101 tctatagtct acgcttcaga aaagaagaat ctcccttatc tcctcatagg aggaaacctc
   104161 catagtcacg gaaacgtctt tatcgttgga aagcttcttc ggattgtacc agcaggtgtc
   104221 gacgcctgcg ttctcccctc cccgcatatc tgaggtaaga gaatcgccta ttaaaagcat
   104281 ttcccgtctt ctctccttgg gacgttccac gccgagaagc cgcatctgtt caaagcagta
   104341 ctcgaaaaat tctttctgtg gcttcgggct tttcgcctcc tcagagacga aaatcccctt
   104401 aaaatacgga tccaggccgc tgcttttcag acgcctgtac tgcgtgtccg ccactccgtt
   104461 ggtgaccacg tacagatcat acttccggct taaatcccgg cagagttcca gggcccccgg
   104521 aatgagaatg gcgctgtctc ccagccgttc cctgtaaaag gcctccgcct ctttcccgtc
   104581 cgcctggcag ttatggcggg aaaagaaaat ttcaaagcgg cgcagcagca cctcttcctt
   104641 ttccattttt ccttcctcaa acagctccca gcagcttctg ttaatctgat ggtactcctg
   104701 aagcaggctg tccttcggct ccatgccgaa atggagaagc aggctcttaa aagcctcctc
   104761 ctccgaagcg tcaaaattta aaagggtatt gtccacgtca aataagagcg tggtatagcg
   104821 gagatttccg ttttctctca tcacccctga taaaccgcct ttccgctgca gatcgtcgtc
   104881 tttaccttac cgaacatctt tctccctgta aacggagaat tggaagactt cgattcaaag
   104941 gggcctgccg caaactcctc ctggtcgtcg aaaatcacca gatccgccgg gccgccctct
   105001 gccagatagc cgctgtccag gcggtacagt ctggccggat tcaggcacat tttttcaaac
   105061 agctccacat aggaaagatg tccttttttc accagctccg tcacgcacag aggcagagag
   105121 gtctccaggc cgataatgcc gctgggcgct tctgtcagag gcttctcctt ctcctccttg
   105181 ctgtgaggcg catgatcggt ggcaatcatg tcaatggttc cgtcctttaa ggccgcaatc
   105241 agtgcctccc tgtcctcctt cgtcctgaga ggcgggttca tcttggccag agagccgaac
   105301 tccagcacag ccgtctcgtc cagagtcagg tggtgaggcg tcacctccgc ccacacatcg
   105361 gcgcccagct tctttgccag agccaccgcc gccaccgcat tcttagagct gatgtgctga
   105421 acattgacgc aggctcctgt gtacagagcg atcatgcagt cccttgccac cagagaatcc
   105481 tccgccactc tgggggatcc gtcgattcca agggcctctg aaacagctcc ccggttaatg
   105541 ccgttgttga taataaagcc cgggtcctcc tcgtgaaagc tcaggggcac gtccagcttt
   105601 ttcgccgtct ccatcgcttt cattaaaagc ttcacatcca taatcggaac gccgtcgtct
   105661 gtaaagcctg cggcgccctg ggcccgcaga gcttccatat ctgtcagctc ttttcccttc
   105721 atgccctttg tgatgttggc ggcggacagc acgtgaattc ctgtctgctc tcccttttcc
   105781 agcacgtagc ggagcgtttc ctcattgtcg atcaccggct ttgtgtttcc catcattaca
   105841 actgtggtaa aaccgcctgc cttggccgcg gcggcccccg tctcgatgtc ctccttatag
   105901 gtaaggcccg gatccctgaa atgcacgtgg acgtcaatca gccccggcgc cacgataagc
   105961 cccgacgcgt cgatcacctc ttcgcctgtc tcaggaagcg cttcctggac ttctgaggct
   106021 tccgcttttt ttaaaatttt tttaattttc ccgtctttta taataatatc tgcaatgccg
   106081 tcaaatccgc ttttcggatc gatcacccgg ccgtttttta taatcatcgc tttctccacc
   106141 tgtattattt catcttctta ggaacgactt ccagccagta attgtccgga tctgcgataa
   106201 agtagatgcc catggaagga ttctcatagc agatgcagcc catctcctca tgcttcttgt
   106261 gagccgcctc catgtcgtcc acctcgaaag ccagatggaa ctcgttgtcg cccaggttgt
   106321 agctgtcctt ctcccagtct cttaaccatg tcagctccag ctgatgggga gtctcgccgt
   106381 ctcccagata aaccaggata aagctgccgt ctgcggcctc ttttctgcgc acctccttca
   106441 gtcccagagc ttcctcatag aactttaagg atttctccag atcgattacg ttgaaattgt
   106501 tgtgggcaaa tgtaaatgtc atagctcaaa ctcctctcct tctctttgaa tttccataat
   106561 gcggtctctg taggggccgc tgcagggaag ggctttcatc cggccggaaa cgccgaagtc
   106621 tccccagaaa tggatgggga atactgcctt cgcctccacc tttttaagga agtcgtccat
   106681 tcccagataa aaccactgtt cctgtctggg atccaggggg ataaaagccg cgtccgctcc
   106741 ctccgggtgg tctgcggcga ttttttccac ctcccgcctg taattggcgg ccatattgtg
   106801 gttccaggcc ttgtcctcgc cctcccacca ccagttgttc aaatctcccg cgtggtagag
   106861 ttccaggcct tccaggctga cccagaaggc gcagccctcg tccgtagact tgtaggtctg
   106921 gattttcact tctccaagct ccagcgtctg tcccggcttc acgaaatgaa tcaggggcag
   106981 agcctccttg gggatccttc tccccttaat gtcgtctgac agaatgtagg aaacgccttc
   107041 tctctcccgg aaccgctcaa aaatcacagg actgtagtga tcctcgtgaa aatggctggc
   107101 aaatacgaac agcggctttc ccggatcaaa gtccggcagc tctcccttaa aatagtcaaa
   107161 cagcagaatg ctgtgttccg tctccacgga aaccgcgctg tggtgaatat aaataacctt
   107221 catatctttt ctctgccttt atctgaattg tttcccgcag cctgattatt ctcctttaga
   107281 agcgttcttt ttctgctctg ccttggctaa aaacttctcg tttccaatga taaaccgctc
   107341 gtgggttccc tcaccgatca ctccggcttc atcataacag gttacgtgga acaccaggcg
   107401 tcttctgtcc acctctgtca gctcgctctc gcaccacacc ttcatgccca gtggagtcgc
   107461 cgcgctgtgg gagatattta agctggttcc tacagttccc tcgccctcgt tcaggtacgg
   107521 agccacgctc ttccaggagg tctgctccat cagagccacc atagccggag tggcaaatac
   107581 aggaagcagg ccgcttccca ttgcggctgc tgaatttgcc tctgttacca ttacttcttc
   107641 tcttcccttg attcctgctt ctaacatatg ttttacctct tttctgaaat tttgcatcta
   107701 taaataaaaa atattttata gttttcttcc gcactggggg cagtaggaaa aatcctctga
   107761 gagcctgcag ccgcagtccg ggcagcttcc ctccccggcc agatttcccg ctcctctctg
   107821 cacgagagac agatcgctct ctccgatatc tgcggcctgt cccctcaaaa ttttcatccc
   107881 tgtctcgcgg ttcagctcat acacagagcc gcagcaggtc atttttacat aaaatttcct
   107941 gttccattta aacagcggga tgaaaaagaa actgaaatac gtgtaggtca tgaagacctg
   108001 gtatcttcca tagccgccgc agacgctgca gatcacagtt ttcaaatatt ccagctgctt
   108061 cacggcggag ctgattcctc caataaaaat cataggctgt tcctcttttc tgaactcagt
   108121 atacaaaatc gccggcgttt tcgcaactgc tttggcaata ttgaccgaat agtctaaata
   108181 tgctatgatc gtggctgaaa ggccgcagct tcgcctgaaa gcagagctga cggccgcaga
   108241 agcaaataag aagaaccgct gaggtaatat atgaaacgag aagaaaaaaa tcagcagatg
   108301 agacgacgca ttatggacag cgccctggca gagttttccg ggcagagcta cggggccagc
   108361 tccgtcaata atatctgctc cgcccagggg atttccaagg gcattatcta ccactatttt
   108421 aagacaaagg acgagctgtt tttagcctgc gtgaaggagt gcttttctct cctcaccgca
   108481 tatatctcgg agagaatgca gcagggggag ggaacggcca gggaacgcct ggagcagtat
   108541 tttacatgca gaatggcctt ttttgcctcc catcccatat accagagact cttctgcgaa
   108601 gccatcgttt cgccgccgga gcacctgagc gcggagatcc agaactgcag aagggagttt
   108661 gacgccttaa atatcgggat tttagagcag atcctggccc agcttccgct gcggaaggat
   108721 catacgaaag aagaaattat tgaaatattc cgccagtttc aggatttcat caacgcccgg
   108781 tattctgccg ctgatctgca gggatcggaa tttgagcttc acgaaaatca gtgccgaaag
   108841 gcgctccata ttctgctgtt cggcatcatt gaccactctg tctcagaata gcggaagttg
   108901 atgctgtttc ataaaataaa tctgcactaa gaaggaacca taattaggat aaaaagttat
   108961 aaaaagtatg ttctcctatg aaaattgaca ttgtttcatt tgtcttgtat agtaactgta
   109021 agacaaatgc tcaaagccgt cttgcccggg caaggcggct ttctttttcc gggcagccag
   109081 gagagactgt ccgcatcttt ataattactg cgataaacga ggaaatctgc ctatgataaa
   109141 accaatctta aaatcattta cctgcatgga tctgcgccag atcgcagact ccggccagtg
   109201 cttccgaatg acggaactct ccgatatgcc gggacgcttc tctgtgatca gccaggagca
   109261 ctatctggaa atcgcgcagc tggagtgtga ctggaagcag acagatgaga cgcgcttcga
   109321 ggcaaaaacc tttgcctttt actgcaaaaa ggaggagctt tccttctggg aacggtattt
   109381 tgatctggat caggattacg aagcctacat aaactctgtc aggaaacgtg attcctacct
   109441 gcagcatgcc gcccaggccg gaagcggcat tcggatttta aatcaggatc cctgggaaat
   109501 gattctgacc ttcgttatct cacagcagaa aaccattccc aaaatcaggg aagctgtgga
   109561 ggcgctgagc cgccagttcg gcacagagca caggagtgcc gtcctgcgtg gcagtcagga
   109621 aaaagaaatc acatggcaca gcttccccac ccccagccag ctggccgaag tctccgagga
   109681 aacgcttcgc gccttaaagc ttggctaccg ggctaaatac attgtccgcc tctgtcagga
   109741 tgcggcgggg ggaaggctga acctggacgc cttcaaaacc atgggctatg aggaggccat
   109801 ggcatatctc aagagtttct atggcatcgg ggaaaaggtg gccaactgta tctgcctgtt
   109861 cggcctccac cacattgagg ccttcccggt agatacctgg atcgaacaga ttttaatgca
   109921 ggaatactac agaaaaaaga agaaaaaata cgacgccctt cccaaaagcc gcctttacag
   109981 cgaaatcatc catgattatt tcggcatata tcagggctat gcaggcgtca tgcagcagta
   110041 tattttttac tatgagaggg tgcagagggg gaaggtaagg taagaaagcc ttgaaacgcc
   110101 agccccccgc cgcagttcac atgcggcggg gggctggcgt tcattttcat ttttcttgga
   110161 tttcctgtct cttttacaga atatctgcct ctcagcagac tgaaaaggtc tagtggaagt
   110221 agccgtagtc gaaggtgctg gtaatgctct ccttcagagc gccgtccatg taggccttag
   110281 aatgtacctg gattctgtag ctgtagcctt ctactacata gtaggttttc tccatcatca
   110341 caatatgtgg tgctcctgct tctgactcct ccgaccagga tttgattgtc ttccaggtgc
   110401 ttccctccag tctctgaagg ttgcatgtaa ccttcactga gtctacctta tttctgttag
   110461 cagaaacggt agccatagca gtcgcttttc cgctgctgct gatatccaaa tcgcctacaa
   110521 cggttgtgaa ataggaccat ctgggatcca cccgcttctg cggtcctgca aaggcagtca
   110581 tcgtcatact cagaatggct gcgatcacta aaagtaactg tgctgctgtt tttttgtgtt
   110641 tcatggtaat acctccatct ttctttttat atataacacg atggaaatct cccctatagt
   110701 gcagctttta ataaaaattt ttatttttta attcgatcgc ttgaatcttc acgctttcca
   110761 gcactttttc ctcctccaga gcggaaatat ttcccaccac tccgaactgg ccggctgtgc
   110821 ttcgaaccac cgtctggctg taatcttcct tctgatacag catcccctgt ctcccattga
   110881 tctccacctc tgtctctacc agatcttccg tatccacctg agaattgtac ggctccttgt
   110941 agtagtaaaa atcgtaccac tgtccctctt ctgccacata tgatataaca aattctccct
   111001 ccttctcttt tactaaagag acataaaacc ccttcaccgt atactccggc tcatactcct
   111061 gaaagtgttc tgtcacgccc ttcctgtcgt ctttctctac cagaagctcg ctgtaggtct
   111121 cccgcacctc cgtgaaaaag ttcagcacag gagtgcggaa ggccgaggag gtaaagccca
   111181 tatacacgct gacagcgagg caggctgcca ggcctgcggc cgccttcctc atccggcggc
   111241 ggcgtttttt cttcttctcc tgcagggcgg ccattttaaa gagctgttcc atcctctcct
   111301 catgctgtct ggaaaacaca tgagctgcgc cgctctgcgc gcctttattt cctttcctat
   111361 tctcccggcg ttcacagctt tcaaattcct tcagctcctc gtcctgttcc agctgctcta
   111421 aaagggccag cgtcaggagc atcttatctc gtttttctct tgtcttcaca cgccttcctc
   111481 cctctccttt ataatctttc caagcttccc tctggccctt tgaagccgcg aattcacggt
   111541 aaactggctg agatttaaaa gctctcctat ctccttcgac gacagttcat taatataata
   111601 aagtctcagc acatctttat acttctgatc cagctggctg atggcggccg ccagatccgt
   111661 cacagatacc cggtcaaaga aaatctcctc tgtgctgggc gcaaacggcg caatctccat
   111721 ttcgatttcc tcgctggaaa tcggctgctt ctgtctcttt ctgtacatat caatcgctgt
   111781 gttcctggta atggtcatca gaaaattttt cgttctgatg tcgctcatct cctccgctgt
   111841 cacccggtca agatttctga ttaccttaat cagggacagc tgaactgcgt cttccgcatc
   111901 ctccgcctga ttcaatatct tataggccgc cgcatacatg gaaccgctgt aaagcgcgta
   111961 caaggcctga aattttgaca gttcgcctgg ttctttgagc attgaagtaa gaattatcat
   112021 gatccttttg ttctttcctc tgtatttctt gaaatttcat acacgggcag gaattcccct
   112081 cccctgcatc tgttaccgca tatcctgccc tacatcaaaa gggcgctgca atccagcctt
   112141 ttgtgtcttc caagccgtcc tgcagcgccg ttgatgcttc tatcgttctc ttttcttgtt
   112201 tctcgcgaat ctattatttc tataagtctc ccgtttcccg gaatcttctg taatggtgcg
   112261 tctttttcgc ctcgtccagc tgggccagca tagacggaat gtcctcattc aggtttcctg
   112321 ccagaaccac gtagttggaa gcgtggtttg tgcggaacac cgttccagga gaatccacat
   112381 gttccaggaa aattttcatt tcatccacaa tctcgtctgc ggttatcctc tcgaaccgtc
   112441 ctgtcaccac gtcgtcgtac atgggagttc cctcataaag gcgaagcgtc aaaaaggacg
   112501 cgtactccgg attcatggcc gatataagct ccgcgcagga tctggcgtgc tcctccacct
   112561 tgctccgtcc gccaagcccg gaaatcagag tcaccgacgt ctggatgccg cagcgcttta
   112621 acttctgtcc tgccgccttt aactcctctg ccgtcacgcc cttgcagata gacgcaagaa
   112681 tttcatcatc ccccgactct gcgcccacat agacgattcc aagtcccgcc ttctgaaggc
   112741 ttttaagctc ctcctcgctc tttctcaaaa tatcctgggc cgttccgtag gacgccacac
   112801 gggtgcagtt ggggaacagc tccctcaccg cctttaaaat ttccagaagc ttctctgtct
   112861 gaagcaccag agcgtctccg tctgccagaa ataccttctg gacataggcc ccgtagctgt
   112921 tgtgggcttc cttcagatcc tccatgatct cctccatgct tctgacccgg aaatccttgg
   112981 ccttgtacat gttgcagaag gtgcaggtat tgtgggcgca gccgatcgtg acctgtacaa
   113041 ttaagcttct tgcctcgctg ggcggacggt aaacaattcc ttcatatctc atcgcaattc
   113101 ttctcctttt tctgtatgat cagccggttt ttcggctgtt tctatctctt cctgtttata
   113161 ccagtctgga aaatcctccc ctgcctgaag aatcagggaa ttgtgatcct ttcccgtatc
   113221 ctttatcatg gcctgaaggt tttcatacca ttctgaggtt cccagatacc ggttccagta
   113281 aaaatacatc tgattttctt ttacatctct gcggttcaca gcagttcccg cgcagtaagc
   113341 gctgttgatc tggccgtaca gcttggccat gtggaatttc ctgtcgtccg gaatggcgct
   113401 taacgcgccg taaacctggt tctgaaccgt ttctatgagg aaatcgccgc tgtactgagg
   113461 gaaattcagc agattttcgt ctgttattcc ctgggacgcc gcccatccgg ccacatccac
   113521 cggacaggtc tcatactgaa cgcttccgtc ctcctgccac cgaagctccc cgtactggca
   113581 gggcggaatc accatggaat ccgacacaat ctcatagatt ccataagatt cctctgcctg
   113641 ggaggggccg ccgttcccat gttttttcac cctctggaga tggagatgtc cgcttatgta
   113701 aacggggagg ccgtactgct ccagcagatc gatcacctgg actgcatttt ccagggtaca
   113761 gtcctccggg tacagagtgc tctccttcaa aagattgtgg tgggcaacag gaatcaccat
   113821 gacctgctcc tctctggccc tttcaagcca cttctccatc cacagaagcg tctccttccg
   113881 gattcttcct ccaattttgt tctccggatc gtactggcag gagtcaagca tcatcagcca
   113941 gtacctctca tctgcctgat aaatgtagct cagggatttt tcgtcccgat ccatggcttc
   114001 gtcatagccg aattcccggt aaatggaata aaattcttca gcgttaatat tgtcggcctt
   114061 ctttttttct gttccttcaa aggaggccgc cgacgggtgg ttaatatcgt gatttcctgg
   114121 aatgacgacc acgggaactc cctggctctc cagaaggcgc agctttttcg ccagctcttc
   114181 atggttgact ttctccccgt tctgtgtcaa atcgccgctc agtatcagcg cgtccggctg
   114241 tttttccgcc gtttccgcca gaaatgcgtc tgtgatggaa tccacatatt ccaccacttt
   114301 tccatcgtcg tttctcacaa aattttggaa cgcctcccca aaatcggtca tcagcggtga
   114361 ctgatagtgg agatctgacg caatgataaa ataaggcggt tcatagggcg gctcctctgg
   114421 ttcttcccct tccttctgcc cggatccgtt ctggctgaag gccggaacgc tgtccgcctc
   114481 cccattttcc tccttctccg ctccgctttc cgtctcattt tcaggccttg aagcatccgc
   114541 cgccccgctc tcctcctgcg gctttgaaag ctccggcaga gtctcggcca gcgtcccgct
   114601 ctcaggcaga cggttccacg gcctgcctcc tcccggcagg aaacggacca ccagaaatac
   114661 tgcggccgtc aaaacagcaa tctccgccag ataaagcaga agcttcactg cctgctgtct
   114721 gtccttctcc ggcttcatgc ttccgcctct tccatgattc tctttcattc tcccactctg
   114781 ctatcctctt tcctccagcc ggttcaggcg ttctaaaata ccgctctcct gatcctcaaa
   114841 cagaagacgt ctgttatatt catagtaccg ttcgcactca tgctcccgca ggaatccgac
   114901 gccgcttcgg ctggctgtca gcccggtgac aaacagaacc atctcctggc tgtctccaaa
   114961 cgccgcctcc aaaaagtcaa agcctctctc cagcttctga agagtttcgt cgcagaagct
   115021 ctcatacgct tcccgatcct ttagaaacag ctcccggacc cgttcaaatc ccggttcaaa
   115081 ctctgtcccg ccttcctttt tgagaatgcc cgcgtacttc tccaggcgct ccgccgctga
   115141 acgcatcaaa tattcctgtt cccggtcaat cagtccggcc ttccgctgct tttcggcctc
   115201 ctcgtccagc tccctggcca ggcgttccag aagggacaga tctctttcgt ctcttatttc
   115261 cttcagcctg ccaaacagaa gagaaatcat ctcctcccgc tttccggcct ccctgaactc
   115321 tccattcaag tgggaaagaa tcagattcac cacgctgaac cgctcgtcga aggcggctct
   115381 ggaagcccgg ctgatcacag attcagacac cgttcccgac agaatcgccc cgatctgata
   115441 ctcggactga tatttatagt agagctccag ataagcggca aaatccttgg caatcctggg
   115501 attttcaata tactgcgccg ttacctccct gtcaaccgtc tttcccagct tttcatagac
   115561 ctcgatcagg cgcgctaaat cctcccagcc tctgggcgtg gcaaactgtt ttcccgatac
   115621 tgtggattca atgcggtaaa aatgttcctt tctggcttcc aggtaggaga taacggccgg
   115681 atgcacagcc gcgttcaccg catacccctt ccacacctca aaatcggcct ccacctggat
   115741 gcggcggatt cgatccagcg tagcgatgtc aaactcccgc accgatttat tgtactccgg
   115801 aggatttcct gcagccacaa taataaagcc ctctggaatc tggtggtttc cgaaggtttt
   115861 gcactgtaaa aactggagca tggccggagc cagcgtctcg gacacacagt tgatctcgtc
   115921 gataaacaga attccctcgg gaatccctgt ctcctggatt ttatcgtaaa cagaagccac
   115981 aatctcgctc atggtgtact ctgtggcctg atattcccgg cctccatagt tcttcttctc
   116041 gatgacggga aggccgatgg cgctctgcct tgtgtggtgg gtgatcgtgt aggataccag
   116101 gccgactctg cactctctgg ccacctgctc cataatctgt gtctttccaa tgcctggcgg
   116161 ccctatcaga aacagcggcc tctgacgaac cgggggaatc acatactccc ctctctcatc
   116221 tttcaacaga taggcctcaa tgcagtcctt tatctcctgc tttgcgcgtt taatattcat
   116281 tatgattctc cttccagttc ttccggccct aaaatcagct taatcgccca gggcggcaca
   116341 tccgcgtcgc tgtaatcttc tctcataaag acaaaagccg tctcataagg cagcattttc
   116401 accggaaacg gcccatagcc gtccgtaaaa tagatcaggc cctttaaatt cgtgaattcc
   116461 ccttccagaa tcagctggtt tacatactca aaggccggtc tgaaatcggt tcctccctgt
   116521 cccaggatct ccatctgatc catgtaccgg gccaaatcct tttggttttc aatttttctg
   116581 tcgctctgca ccttttcatc acactgcaga atgcggacgt tcacctgagt gaaaaagctc
   116641 tcagactctg agagcacctg gtacgtctgt gaaagaaact tctttaccag atctccggag
   116701 caggacatgg aggtgtcgat gacaatgaca aactcctgga ttttcttaat ctccttcgtc
   116761 tccagcggct caatgagagg catatttccg taggtcctga ggccgtagtc atagtagata
   116821 tagtcaaatg cgtccatatc cacctgcatg gtttcccgca tgacggaaaa ctgcctgaga
   116881 aattcccggt aatctgtctt ttccctgttt tcgatatgaa tctgggttct caaatctccc
   116941 gcctcgccgg aaggcatttt ggagaaggtc tccatctccg tttccatggt ctgtctgatt
   117001 tcctcccagc gattctgcct ctctctggag cggttaggct tcctgtcgtc ctcccacaga
   117061 tcgtggctgt ccgcatagaa ctctgcggca atccgcttaa gcctgccctc gctgaacgct
   117121 tccttctcca gcgcgtcgta aatcgactgg gcgttcatca ccgctgtctg ttttttcagc
   117181 cgttcataca tttctctgcg ggccggagag ggggggagcc tgagggcttt tataagaaag
   117241 ccgtcaatca gcgcctccgc cgctatatcg caggacagat cccagagatt tttctccctg
   117301 ccccgtctgg tgtccatgtg cagaaagatg cagtgaagca ccatatgaag ataaattcgg
   117361 tttacataaa ctctgcctct gcggtacagt aaaaccaggt cctccggctg aaagcggagg
   117421 cagaatccgt ctgtcgccac gcctcttctc tgcgtatccg gcgaaaataa aagtgcgctt
   117481 agagccgtat ccataaatct cagattcaga tacagctcgt ttcgcgcatt ccttaaaatt
   117541 tccccgcaga tatcacagag ctcctgagcc ttctcctgct ccagaaagat gggggatttt
   117601 tccatggcct atgcctcctt tgtccttccc gcatgatcct ttcccgacgg acgctccgcg
   117661 gcaggcacag gaaccggcat ggccccattc tttcccaggg acaccttcag aaactcctcc
   117721 atggcttttg tcatatattt atttctcttt ttataaaaat acacgttccg gatggccagg
   117781 ccgtcgtcca tcttgtagta gcacagaggc acgtcaaagg gcacgctgct gaccagggcg
   117841 tccggaatga aggtagctcc catgcccttg ctggccatgt tgaaggccgt gatcacctga
   117901 tccggcttca ggataatatt gggggtataa ttctggcggc tgcacatttt tactcccctc
   117961 ttataaatgc tgttctcctc cttcaggaaa ataaagggag ttttctttag gagaggcagc
   118021 ggcagctccg gaaattctct ggactggtag gctccgctct cgatagattc ccggctcagt
   118081 ctgtactgat tcagttcctg gttgatctca aacccggagg gaactgccag cacaatccgc
   118141 tctgtactgt aatagtattt atcgtaattc ttgtcgtcca tctccgaatt gtcgatgaga
   118201 aggtcaatct cctcggaaaa cagcttgtcc gtcagctggg acgtagttcc ctccaccagc
   118261 tcgatcttaa tctggggata tctgcgggaa aattccgcca gaaggctggg aaggatatag
   118321 gaggtcagaa aaaccgtgcc tccgatggtc agctttccgg ctaacaggcc gtttaagttg
   118381 ttcagctggt taatggtgtt ctgttccaga gcgaacagct tctcgatggc gtcaatgtag
   118441 acctcgccgc tgggcgtcag tccgatgggg gaggtactcc tgtcaaaaat agggcttcct
   118501 atcttttttt ccaccttttt gatggccgtg ctcagggccg gctgggtgat gtagagcttc
   118561 tgagcggcct tggaaaaact cttttcctcg tagaccgcgt acacatattc ttttccgtca
   118621 aacatgttct ctcctatatc tttcctataa ttaaaaatta atagttatta tctttctata
   118681 tgaattggat tatatacgaa ccctgttata taatcaaggc atagcataaa agttgtttta
   118741 tgaattatca cagttcaaac gtacggcgtt ttggcggaaa ggccctgcgg cctgcttcca
   118801 tcaggatgcc cactgcttcc gtctgattca ggcggccggc agtttcaacc agcttatcaa
   118861 agccggtttt ccccaaaacc ggttccttta tatttgaata ttcctcgtga gcacgccctg
   118921 ccaaaccctc attccccaac caaaccgcag cggcgtgctc aacccttttt atcccaaaac
   118981 actgatttac aagccagtcc cactccgcag cgtcggacag ggacgcaata tactcccctg
   119041 tctcatccag gtggtcaagc agatagaact tataggccga ttctgcctcc ctggacagcc
   119101 tcagaggaaa acgcagcctg tccgccgcca gttttacggc ctccggcaca ttttcctggg
   119161 ctttcatata gggaaagagg ctgtcgtatt cccggaataa aagctgcgtg ttctcaaagc
   119221 agtagcggta tctgtggccg cagccgtgga catgggtttc cgtaatccgg gccggcgtat
   119281 tttccaccgc ctcctcatag aaggccggaa agagaagctc tgccagaagc gttttcttcc
   119341 caatctctcc cctctcccgg tagtgaactg ctaccgtctc atttaactct gataaaattt
   119401 ccttcaggca cgatttttct ctgggatccg cctccaccgt cagctcctca atctttctgc
   119461 agccgttgaa ggccccagct ccgatatccc ggatggcgga gggaaaggcg aggcgtttca
   119521 ggccgtcgca gttataaaaa gcataccgcc ccagccgctt caaaaaagca ggcaggcgga
   119581 ccgaccgaag agacgggccg cagaccgggg gagcggatat ctcctcatct tccccgttct
   119641 cacgccacag aagccctttg ggctcggtcc gcattccttc cgaaaagata taatccccca
   119701 gctcagccac cggaagtcct tcgatttgat ccggcagcca gatctcgtcc gtctccccaa
   119761 agcagcggag aatttttacc gagtcttctt tcttctcata gagcagttca agtcccattt
   119821 cacgtatcct ttctgttaaa cgccggttcc ggccatttta tcagcccagt cccagggctt
   119881 ttacgatcag aaaccagacc ggaggaacca gcagggacgg aagcatattc atggttttgc
   119941 agtccttgat ttttaaaata gacaggccgg aggcggcaat cagcacgcct cccacaatcg
   120001 aaatctccgc catcagaggc tctgacagaa atcctgacag cgcgctggct cccagataaa
   120061 tcgatccctg ccagcagaat aaaacggccg ccgccagggc aatcccgatt ccgtaggtgg
   120121 aggacagggc gataaacgtc acaaaatcca gagtggcgtt ggtatagaga tacgtgttgt
   120181 ttccatatat ggcgctctct atgggcccca ggatggacat ggttcccacg cagcacagca
   120241 gaatcgccgt ggaaagtccc tcccccagct gggaagcgtg gaagctggcc atcatcctct
   120301 gaaaccggcc gtccaggtca agaagcgtgc ccgccaggct gcccagggcc agactggcaa
   120361 taaagagcac cgggtaacgg ctgtccgaca tgccccctgc cgcagaatga acgcccagca
   120421 tgagggccgc caggcccatg gcgttgaaca tggctccctg gtactcctcc tttatgccct
   120481 ttttcaccct gcttccgatc aggctggctg ctacgattgc gcctacattt acaatcgttc
   120541 ccgtcatgcc tttccttcct ctccgtccag actccaccgg atcagccggt cgccgctgta
   120601 ttccagcttc agggaaaaga aggggcggtt ctcctccaga aggcggaaaa agattttatc
   120661 cccctcccag agatttaact ggtccagacg cgttttgtct acccactcca gggttccctc
   120721 gctgcactcc tttatcgttc cctcaaagcc gtccgcagta aacagacaca tatattctgt
   120781 gggccatccc tccgccagaa aggtgaccag acctcggaaa cgccaggagg taagggtaag
   120841 ccctgtttcc tcctccgcct cccgcagaag acattcctcc gggctttccc cctcctcgaa
   120901 atggcctcca atgccgatcc atttatcctt attgacgtcc ttttcctttt ttacccggtg
   120961 aagcatcagg tatttctcat cctgctcaat atagcacagc gtagtcagct gtgatttttc
   121021 tctcatcata aatcccgctc ctgtttctat tttccgcaga gttcgcctga cacggatcta
   121081 gtccagatac agctttccaa agtccttggc ctcgtcctcc agaatcctcc tgagaaaatc
   121141 gctgagttcg ctggcgtact ggtatttatc ccacagcctg gccgcaggat catccttgac
   121201 ctcgtctgca atctcataca tctttccgcc gtaatagtaa acgcagagct tggcgtagaa
   121261 ctgggacatg gtctcgatct cgtcgccgga caggtgaagc gttcccttcc tgttctgccg
   121321 ctctaaatcg ctgaccgcgt gttcgtagga aatctggtgc aggaaatttt cgctgtaatg
   121381 gaagaaatca gccagatccg ggttcttgta ggaattctct ctcgcccatt tttccacatt
   121441 gaccgtctct gtgtgatagg taatcgatcc gtcctcatag agatccatca ctccgtagcg
   121501 gcagggagcc atcaccagag agcctgtcac cacctcggcc acatcgtcct cctccatgta
   121561 gtgctgcaga tgaaggtggc cgctcagatg aagtctgacc tcgttgtcgg aaagcatctg
   121621 cagaagctcc tcgctgtgtt cgatggtgca gtcatcatag aaggcgtcgc tgactccgct
   121681 ctgttccagc agattgtggt ggctgactgt gatcacctcc gtgtcgtttt cccaggcctc
   121741 gtagagaatc ggctccatcc acttataggt tccgctctgg atcattccgc ctacctgatt
   121801 caccggatcg tactggcagg agtccagcat gagaagccac aggctgctgt ccaccttgta
   121861 cagatagctg agagaattgg gatcccggct gtcggcggcc acatagccga attccgcgta
   121921 aatatcctcg aattcctccg ccgttatgct gtccaccgga taggaattcg tgccggaaaa
   121981 cttcttggca ttgggattgt taatatcgtg gtttcccgga atcactaacg tcgtgatccc
   122041 ctcctcgtcc agctcctcta aaaggacggc aagctcctcg tggctggctt tctctccgtt
   122101 cagcgtcaaa tcgccgctga gcagaagaag atccggatcc ttctccttca tatcctcaat
   122161 aaaagcatcc agaatttccc agctgtagag aagaacgcgt ccgtctcctc cgtacacata
   122221 gttgatgaag ctctgacacc gattgcccgc cagatcctca gccagatagt ggatatccgt
   122281 ggccagcaca atctcataga gcggctcctc gcctgtctct gcctgggttt cctcctctgt
   122341 ggtttcctcc aggctctccc ctgtctccgg cgcttcttct ttgctttcct ctgtctctct
   122401 gcctgcgttc tggctctcag acggttttgt ctgtgcctct gaggtctgag cctcctgccc
   122461 tgtctgagct gtcttctggc agcctgatac agtaaggcac agtcctgccg caatggcgaa
   122521 tgccgccgct tttctttttc tcataaaatc cttttgtttc ctttcccttt tctctaaccg
   122581 cagcgcctat acataggagt gatcaatctg gataatcgcg cagcagcacg gcatggtttc
   122641 gcacacctga tcctgtacct gctttttaag ctcctcctcg cccattttca tttcaaaggg
   122701 catcaccaca tcgaacagaa gctttgtcac tccgcctccg tgaaccagac ggaaatcgtg
   122761 aatcgtcagc cggctgtcca ccgccttcac gatctgttca accatggcct ttttctcctt
   122821 catctccgga tcctttaagt ttaccggatc catatgtatc accgcctggc agcccagacg
   122881 ctcctgcagc tccatctcca ccccgtcgat ggcgtcgtgc agctcgaaaa tatcctggct
   122941 gccgtccacc tccccgtgaa gggaaaccat cctgtggcca gggccatagt cgtggacaac
   123001 caggtcgtgg attccgataa tctccggcct ggagaggaca atgttctgga tttcctcaat
   123061 aaactccggc tccggcgcct gtcccagaag cggatttaac gtctccttgg ccgcctcgta
   123121 accggctttc aggataaaga cggccaccag gactccgcac cagccgtcca cgttcacccc
   123181 tgtaaacttc atgatcagca tggagatcag aaccatggaa gtggccagag cgtcgcttaa
   123241 actgtccatc gccgtggcct tcatggcagc cgaatcgatt ttcgccccga ttctccgatt
   123301 gtagaagctc atatacagct tgactgccac agacgccagc agaatcgcca tggagaggac
   123361 tcctgtgtcc actgcctccg gatggatgat tttctcaatg gaagaccgcc ccagctccac
   123421 gcccatgacg ataatggcga tggatacggc cagccctgac agatactcga ttctgccgtg
   123481 tccaaatggg tgttcctcgt ccgccgcctg gcctgcgaac tgaaaaccca gcagcgtaat
   123541 cacagaagat ccggcgtccg acaggttgtt aaaggcgtcg gccataacgg cgatggagcc
   123601 actcaaaaat ccagccagat atttcccggc aaataaaagc aggttcaggg caattcccag
   123661 ggttccgcag aggattccgt aagccctcct ctcatccttt ccctgcttga taaaaatacg
   123721 ttccagcagc gtaatcattt cgtttcagcc tccttaagaa atacatattc gcagtctgag
   123781 gaccgctccg gacagaagga aaatcccatc ctgtcaaacg ccttcgcctc ctccggcgtc
   123841 tctgctcccc gctccgctaa aaagcgcacc atctcgcccc tggccatctt ggcctccgtg
   123901 gccttcacct tgacctttcc ctccgacagg gttccgaaca cgcaggtgac aaatctgtcc
   123961 ccggaagcca gataaggctc caccgcgcgg ctgtactcct tagaggccag atttaaaatc
   124021 accgccggcc ttccctctga aagctctctg taaatcttat ctccccacca gccgtacaag
   124081 tccttatgta aacctatttt cagcctggcc tgcatctcca ggcggtaggg aaccaccccg
   124141 tcgtcagccc gcaggacacc gtaaaagccg cttaaaatcc gcagatggct gcagacgtac
   124201 tcccactgtt ccttcgtaaa aatctgggga gccatatatt ggtactgaat ccccacatag
   124261 gccagaaccg caggcgtcag cccctgatcc agccgcatcg tctgatacct gagataattt
   124321 tcatgggtaa tggcgtcgtt ggccttaaaa agcgccttta attctgcctc agaaaagccc
   124381 tgaagagtcc gcaaaagctc tccggcctcc ttctggaata ccggcgcggc cctccagggc
   124441 atatcgtcgc atttcacctg catccgcttg gcaggcgata caatcagctt catagccaca
   124501 gcttctcttc tccctctttt gcagttaaat tcctccacca gggcctcctt ctgggctctg
   124561 gacagcctct tgatggctgc ctcccgcctc atggcctcgc ctctggtaga atattcctca
   124621 aaataagcca gggccaccgg cctcctggct ctcgtgtact tcgcaccctt cccgctgttg
   124681 tgggcggcaa ctctcttctc cagacagttt gtccacccgc agtagagcgt gccgtcgcag
   124741 cagcgcagaa gatatgtgta attcatctgc ctcgcacctc ctgtccgggc tatgtaaacg
   124801 gcagctgcac cctgcgcagt catgctgctg ccgcccggag ccttaaaaca gacagagcct
   124861 gaaaccccgt atctatttaa agcatcggcc agatgcggac gtgccttccg gcctcccgga
   124921 aaagcgctgc ccttccagtc atactctatt atatgaattt tctcccgaaa tgcaactttc
   124981 atccccggat ttttttaatt cttctttttt ctgctgtcaa aatacaggaa ctggtcaatg
   125041 gagtccagaa tatccgcgaa atcctccctg ggagccaggt cgatataccg gcttaaaagc
   125101 tccgtctcct gctttttgta cctgccgtaa aagatgtcga acaggttatg gccccgcaga
   125161 tgaatcttga acagatccat atgttctttc agatcctccg gagattttaa atcccgtccc
   125221 agggccgcct taaacttctt ccccgacgtc aggcggcaca gatattctct ccacttttca
   125281 tacaaaatat catagaacac ctcctctgac ggaacaacgg acagctttgt cataatttca
   125341 ggattcagga aataattttc aaaggaataa tacctcagga tcagcacgtt tttctccgtc
   125401 accctgggca ggtgatccac atcgcgcttt ccctgctcct catagtaccg gcacagctgc
   125461 cttttcagct ctcccctgtc ctttccgtct ccgtcccgga tcatgagaaa ctgatcctta
   125521 aaatgcacct ggttcatgta ctttaagttg gcgtaggtct tgatattggt gcagctgttg
   125581 gtggtaataa tggagactct ggacaggctt ccgtcctctt tatacacttc ggaataatat
   125641 tttttaagca gcaggggaag gcggctcttg tcctgcctgc cctccactat aaacacgaag
   125701 tccacgttca tggcgtcccc ggccccgtag cccagatcgt ctaaaatttc tccaatgtcc
   125761 acctggctgc ggacgacaga agagaattcc tcatcaagca ccacctggcg gatctgcctg
   125821 gaggtgaaat ttaaaagcag ctggggcgaa tgcgtgctga aaatcacctg attcttctta
   125881 gacaggcggt acaaaatctc gctggccgtc ttctggagtc tggggtgcag gaataattcc
   125941 gggtattcca ccacaataat gctgggcagc tggctctcct cctccacgta ggtttccaga
   126001 agagacagca tatagatgca ccgcatgccg cggctcatct gggagacagg gctgaccgtt
   126061 cctctctcct tgctgtaaag ctccgcctgg acagaaaaca gctcggtgag atttccctga
   126121 agccggtagc ggatttcatc gaaaccgccg tttttctcga aattttcatt gatccgctct
   126181 gccaccctgc ccagattcaa ctgatagagc ttgtactcaa acagcttctg ggcctccagg
   126241 gcgtttaact cctccggctt tttttggtta atcaggccga tacactgaaa gcaatgggag
   126301 caggcccgcc cggaatcaaa caggcaggcc ccgtttctca tctgattcat cagacggctg
   126361 tcccccagaa ggaacagatc gctctgaaaa gcgttcagct cccgctccgt atcaatgtag
   126421 tggagctttg gaatcacctg ggctatgtag ggattgtgct tcctgaagcc gtcaaaaaac
   126481 ctctttcttc cctcccggtt tacgagaaag gtaaaggaga gaattccatt ctggaaggag
   126541 ggcagcttct tctcaaaatc acgtttccag atctcaaacc ggcggtaggc gctgaccaca
   126601 gcctggctgt gaaacaaaag caggtcctcc tcctcaattt taagctccgt ctcaatctcg
   126661 atattctgtc cgctctcgtc aaaatctccg tccagaacct cccgtccccc tgtcatcaga
   126721 cggacggcgt ccagcacaga agtcttgcct gtattgttct tccccaccag gatcagggcg
   126781 ctgtcaatgt ccgacagctc catgtcccgg atggatttaa agttcttaat ccgaatgcgc
   126841 gtaaacctca cggcagcccc tccttcccct cttttgttcc ctttattata cggctttcac
   126901 cgtccgcttt caaatgattt ctggcgccgc ccagtgtgaa aatctctgcc tatcctgcct
   126961 ggtgccgtct tctcactggg aaatctcctt caccagtacc agccgctccc ctggacgggc
   127021 ctccccccgc tccaggccgt tggcctccat cacatgatcc acagtagtgt gaaatttttt
   127081 tgcaattttc cacaaagaat ccccaggctg cacaatgtag cccacaatac cgggcatttc
   127141 ctgaagcttc ttcagatcca gaggctctgt cctggccccc gtaatcacct gctcgcacac
   127201 cggctgaaga gccagaagat ccgctgtgat cacagccttc acctccacgc tctccgaccc
   127261 cagcatcacc gccgtcagct gttccagccc catattcagc tgatagacgc tgttttcgtc
   127321 cattccgctt gcctccgccg tgcagcggaa gggaaccatc tcctccgcgt agcccacagg
   127381 agccgcgtcg tcgtccgtca ggtagagaag gcccacctcc agaactcctt ccagatgaag
   127441 tccgtcctcc ttcggctccg ccgcatccag ctttacctct cctgtgctgt ggcagatctg
   127501 aagaatccgc tccggctggc gcagattaag cttttcagct gtcttgcatt tgcagatatt
   127561 ctttgtcaaa agccggtcaa aacaggctgt tcctgtgtcc agaaccagct cgcatcccgt
   127621 ggaatacata tcgcttaaaa gctccacatg ctgctcctcg tagagcttca tatccagttc
   127681 aagaaccgcg tctgccagaa gcacccgcat ctccccgtcg ctgtccggct tcatttcaat
   127741 ctcctgatga agcaggcgca ccggcacaaa cgggatcatg ctctcctctg cctcagaaag
   127801 ctctacctct ccggaaaacg ggatgctttc ctccacccac tgaaccggcg tatgctcccc
   127861 ctccccgctg tagatgacga agattaaaag ctctccctcc agatgaaccg ccccctgaac
   127921 cgggctgcag gaaacgccgc gcagcttcat ttctctccac agaatcgtct ccatattcgg
   127981 cttgttggct gacagggaca gctcctcccg aatccggtag gtatcctttc tcctgacggc
   128041 aatggcggcc acgtcaatgt cccttcgctg gatttccacc ctgccgtcgt ctgtcttcac
   128101 gtccacagcc gcctccgcgt cgtacaggct ctccacccgc acctccagca tcaccaccgc
   128161 cttgatattc agcttcctgg aattgatcat tcccgtgttc aaatcctcca ggttccagga
   128221 gacctgaaag ctgtccttct cctccagctc cggcacgttc accgtctcct caaaaggaat
   128281 ttcccccttc agagactgga ggccgcccga ttccctcctg tataaaaccg caaaagaaag
   128341 ctttccccgg atcagcaccc ggtctccctg ggctctggag gactcaatct gaatatctcc
   128401 gtttcccagc agtacggcag atacgtcgtc catcgtatca gggacaataa aatcgtcgtc
   128461 aagggtaatc tgggacactg cggttccctt ctgccggttc atgtgaatgt tatttttcat
   128521 cagctccatc attttgccac cacgcctttc catttgatac agactccgcc cgttcttctt
   128581 tgccgggccg ccggcagaac ctatctcccc ttccgccggc gctttgtgaa agtctatgca
   128641 tggaaaaggc gggatatgcc ctgctcacat gggcatatcc cgccttttcg gcgcgttctg
   128701 tattttggcg gcagcgggcg cggccgccta ttttttcttt ctgaataaaa tcatctgagc
   128761 ggcaaggaga atccccgccg taatcagaaa catggccagg ctgtggttca gaaggcctgc
   128821 atactgataa aatccccagt atatcactgc gtaaagaacc acaactacaa ggatatagag
   128881 cattctctcc ttctttcctg ctcctgacag cagagtaaaa ttccccagat actttttatt
   128941 cagccagagt gagtaaatca gaaaaagaag gattcccccc aagagcagaa tcaaaacctt
   129001 catatctcca attcttccat acagaccggc ccccagcagg cagaccgctc ccagacagat
   129061 gctggataca gcgccttttc tgatatactc tctgcgctgt tccggctcca gctcctcggt
   129121 ctgcctgatc tgaaaaaatc tgagatccgg ctttttcagg cggactaacc cctctgctat
   129181 gcagataagc ccggcaatca tcagaatcat gctccactgc ttcatcccgc cccccctttc
   129241 actcccccgt gcactggcgt taatactctt ccagaaaatg atggcgttct tttcccttca
   129301 catatccgat gcaggcgtcc agattgacgt tttccacgct cttgaaaata ttcgtctcga
   129361 tgtgaggatt gatggtcctg aatttcgcaa tcagctcctt catctcctgg cgcttcgaca
   129421 tgtgggcctc ctcttccctg gaaatggcct ccgtaaaccg gcaggcgcac tggagaaacc
   129481 gaagattgtt gaaatcacgc cacgcctcga tatccgcctc cttcaccaga tacagaggac
   129541 ggatcagctc catgccctca aaattggtgc tgtggagctt cggcatcatg gtatttacct
   129601 gggccccgta gagcatgctc atgagaatcg tctcgatgac atcgtcaaaa tggtggccca
   129661 gggcaatctt attgcatccc agccgctttg cgttggcata gagatggccc cggcgcattc
   129721 tggcgcacag gtagcagggc gactgatcca cgtccactac cacgttgaag atatccgatt
   129781 caaacacagt aatgggaatt cccataatct ttgcgttttc ctcaatcatc ttcctgtttt
   129841 ccggattata gcccggatcc atcaccagaa aatgaagtcc gaactccatc tttccgtggc
   129901 gcagaatctc ctgcatgcac ttggctaaca gcatggaatc cttgcccccg gaaatgcaga
   129961 ctgcaatgtt gtcgccctcc tgaatcatgt cgtactcgtt cagagccttc acaaagggcc
   130021 gccagatttc cttgcggaac tgcttaatca cgcttttctc aatgtctctg caccggtctg
   130081 ccggcttttt ctggttgtct cttactgtct cgttatcctg caattttacc atcctttttc
   130141 tcgcctttgt ctttttcgtc cagctcccgc tccatccggc gcagctcccg cttcagctgc
   130201 ttgttctcgc cctttaaagc ctcaatctgc tctaccagct ttctgtcgtg ctctcccaga
   130261 accacttttt ctttcttctg gatcttcacg ccgtccttct taaccgggcg ggccggaatg
   130321 cccactgccg tgatgttctc ctccagcggc tgtaaaagca ccgcgttggc ggcgatggag
   130381 cagttgtctc ctacctggaa ggatccgaga atcttagctc ctgaccccac cgtcacgttg
   130441 tttcccagag ttgggtggcg ttttcccttt ttcgtgccca cgcctcctaa cgtcacgccc
   130501 tggtaaatgg tgcagttgtc tcccactacc gcagtctctc cgatcacaac gcctgcgccg
   130561 tggtcgatta aaattccatg gcccagctgg gctcccggat gaatttcaat cagagtaaaa
   130621 aatctggcaa tctgggaaat caggcgggca ataaaaaaca tccgtttctg ataaaaccag
   130681 tgggcgattc tgtgccaaat caacgcgtgg accccctgat agagcagaag cacctccaga
   130741 gcgcttctgg ccgccggatc ccgttccttt acagctttta catcaagcca aatatccttt
   130801 aaaatcatag ccttctcctt ttaaaacaac gctgaaacaa tacactgtga tattgctaca
   130861 ttatataagt attccgcagg ttctgtcaat gaggtctgcc gaagtttcat gcctgcagta
   130921 ccgctatccc tgccttgaaa atatcgcatc atttctggaa agaagatata cgcagtattg
   130981 gttcatgctg attccttctc tctgagaatg ttctgccagc aatctgtgaa gactcctcgg
   131041 aatccttagc ttaaactgcc cagaatagtc ctccaggctg tctggctcct ggattgccac
   131101 tccatcctct aacgccgcct cgagccacgc tttttttgca tccagcgcat ttgccactgc
   131161 actttctact gtctctccac aggtaatgca gcctggcaga tcagggtaag aaaccacaaa
   131221 tccgccctcc tccttgtctt ctacaacctc cattcgatag gccattgcca agtattcttt
   131281 cagagtttta ctcatttttt gcctcgcttt ctacaacctg ccttaccatt tccacatata
   131341 cttttttgat tggttcttgc ttaggtatcg tgattggcgc gcagccctgt tttctaaatg
   131401 tataatggct gcttccccct ctcggcgcat tcatttcata tccataactt tccagtatct
   131461 ttcgcagttc atcaaaccga agatcttttg atagtctatt gatacgcatt atcaatttat
   131521 cccattgaga cattcctatt cctctttctt ttattatata tggtgtcata tatggtgtca
   131581 atgctttgtt tttggcagaa caggcccctt tcctgtgcct cgaatatcga aaagaggaac
   131641 cgttttctta ctccgcttaa atccggcgaa aacgattcct cttttcatca tttcctgtct
   131701 actctccaaa taccatctgg cacagcctga cgtactcccg gtattctgga aagctctcca
   131761 gttctttaaa ggcctctgcc atggaggtat aataccaccc ctgccagcgc ttttctttca
   131821 tgttaaaccg ctcaaatact gcgtctccgt ccagcagata atctctggcc gtgttccgca
   131881 gattgctgag cttgtctccc agagccagaa tcttctcatc ccgtccggct cctttcaggc
   131941 ggtcaatggt cgcctgcttt ctctccctcc aggatctgga cttgtcctct gtctcgcctg
   132001 ctaccagttc ggccacccgg cggccgaact ccccctcaat ttcactgaac gtgacccctg
   132061 cgtcttctat ggtatcgtga agaatcgcgg ctgcaatcag ctcctcgtcc tctgtgaggg
   132121 aggacacgat cagagccgtg tcaaggggat gggtgatata gggaatattt ccgcccttcc
   132181 tcaccgcccc tttgtgggcg tttgccgcaa atactgccgc cttacgaatc atacccttac
   132241 tctccatcct gaactgaacc tgtaatgtga acgtccatct gcctgtacgg aatctcaatg
   132301 ccttcctcgt caaaggccag cttgatcttc tctgtaatat cccatctggc ggcccagtag
   132361 tcctctgact tcgtccatcc cctggctccc agcaccacgc tgtcgtctcc cagggaatct
   132421 acataggtga caatcggctc ctccttcaga acagacggat gctgtctgta aatccgatcc
   132481 atgatttcct tggccttcct caaatcagac tggtagccga tgcccaccgt cagatcgaga
   132541 cgccgtttct ccatggccgt cacattggtg acaatagaat tggacagcgt gccgtttgga
   132601 atggaaatcg tcttgttgtc aatagtcacc agaatggtgt acaccagacc gatgacagat
   132661 accgttccct cggcatttgg catcacaata taatcgccta ccttaaaggg cttcatcacg
   132721 agaatcaaaa tgcctcccgc gaagttttta aggctctcct ggagagccag gccgatggcc
   132781 aggccggcgg atcctaaaat cgccacaatg gaggcggaat ctattcccag ctggcctgcg
   132841 ataataaaaa tcagcagcgc gttcagggaa aatttcagca gagagccgat aaatttcgtc
   132901 actccgatct ccatccccgc ccgctcgaag gaatggcggg ccatctttaa gagcagacgg
   132961 attattttcc gtcccacaat aaagatgact aaaataacaa gaaggttcaa gccaaaccgg
   133021 atgagatccg gcacccagcc cttcagggcg tccatcagca catccggctt tccaaactcc
   133081 tgaagctcct ttaaatcctc tcccaatgcg ctgatcgcat ctgtttcctg tgttggtgtc
   133141 gataaaaaaa tcatttattt acttctcctg cctgtctgga gggctttctg agctcccttg
   133201 atcactgtga ctacaggatt tttgttttcc ttctcccggc tctcctgcgc cgttttcctc
   133261 tgggactcat ccctctcctt cttctgtccg tccatggcct gcttcagcgc ttccttggcc
   133321 tcatcatcct ctctcaaatc agccagagtc ccgtaaaggc tcttatccgc cttaaaggcg
   133381 atcacattgc tctccgggac cttctcctgt gcagaggtcg tccttctgcc tcctgcggcc
   133441 cctgaggatc tgcctgctgc cgaagctctg cctgttcccg cggccttgct ttttgccgtc
   133501 ttcccggctg tcctggccgc ctttttcacc cgcttcaccg gagtgcagga gaatacgctg
   133561 attccaagcg gggcaatatg aacggtaatg gactcctctc ttccgtcgca ctcttctgcc
   133621 ttggagctct tcacccgcgg gttcacaatg ccgcagccgc cgaagttctt ggactcgctg
   133681 ttgaaaatct ccttatactt tccggggaac ggaactccca ccttatattt ctcatgctcc
   133741 accggagcga agttgcagac aaagagcagc gtctcctccg gcttgtccgt ctttctcagg
   133801 aacgccgcaa tgttatttgc agagtccatg cagttaatcc actcgaagcc gtccggcatg
   133861 taatcctcct cgtaaagagc cggatgctct ctgtagagga agtttaaggc cttcacatag
   133921 gactgcatat ttttgtggat cgggtactct aaaagctccc actccagact cttattttca
   133981 ttccactcgt ccatctggcc gaactcctgt cccataaaca gaagcttctt gcccgggtgt
   134041 cccgtcataa agccgtaggc cgcccgaagg ttggcaaact tggcctcgaa ggtctctccc
   134101 ggcatcttgt tgaccatgga tcccttgccg tgaaccacct cgtcgtggga gaacactaga
   134161 ataaagtcct cgctgtaggc gtaaatcatg ctgaacgtca gctcgccgta gtggtggcag
   134221 cggaagtagg gatcgcactt catatatccc aggaagtcgt tcatccagcc catgttccac
   134281 ttataatcaa agcccaggcc gtcctccttt acgtttcccg tcaccttggg ccaggctgtg
   134341 gactcctcgg caatcaggac cgcgccgtcc tttctgccct taaatacgga attcaggtgc
   134401 tttaagaact ccaccgcctc caggttttcg tggccgccgt acatattggc aacccactcc
   134461 cccggattct tgccgtaatc caggtacagc atggaggcca ccgcgtcgaa gcggatgccg
   134521 tcggcgtggt acttgtccgc ccagaacatg gcgttggcaa tcaggaaatt cgatacctgg
   134581 ggccgtccgt aattgtagat cagtgttccc cagtgcgggt gggctccctg tctcggatcc
   134641 ttgtgctcgt agacgcaggt tccgtcaaac tgggccatgc cccaggaatc cctcgggaaa
   134701 tgagccggaa cccagtctaa aatcacgccg atgccctggc tgtgcatgta atccataaaa
   134761 tacatgaaat catccggcgt gccgtagcgg ctggtaggcg catagtagcc cgtcacctgg
   134821 tagccccagg aagcgtctaa cgggtgctcc atcaccggca gcagctctat gtgagtgtaa
   134881 cccatctcct tcacataggc ggccagctca ggagccagct ccctgtaatt gtaaaactca
   134941 gagcccggaa ccgcctcccc ggcctcgtcc agggaaaatt ccttccgctt ccaggatcct
   135001 aaatgcacct cgtagatcga catgggcctt ttcttgctgt ctgagaccgc ccgttccttc
   135061 atccatttcg cgtccgtcca ctcatagcca ttcagatccc atacaatcga agccgtattc
   135121 ggccgaagct ccgcataatt ggcatacgga tctgccttta acgccggatc tccgtttctg
   135181 aacttgattt catatttata aaccgccccc ttggaaagcc ctgggataaa cagctcgaat
   135241 acgccggaat ctcccagcct cctcatctgg tggcggcgtc cgtcccagaa attaaaatcg
   135301 cctaccacgc tgacacgcat ggcgcacggc gcccacacgg caaagtatac gccgtccacg
   135361 cccttaatgg tcatgggatg ggctcccatc ttactgtaga ccgagtaatg aatgccggcg
   135421 gcaaatttct tcaaatcgct ttccgtaaac tggggcgcaa acgaatacgg atcgtgaatt
   135481 tcccccagcg ttccattgtc atagaacacc tgcagcgtgt aatccgtcaa agtcttcctc
   135541 ggaatcagag ccgcaaaaaa gcccgcctcg tctgccatct ccatgggata cgtctttccc
   135601 gttccggaaa gcctcaccgt aatattcctc gccgtgggaa taaacgcctg cactaacatc
   135661 ccattctccg tgagatgcgc ccccaggatc ctgtggggat ccggagactc agaatacacc
   135721 agctcctcaa tccccgccca gtccatcaga tcatataata gtttgtccat aaatacgccc
   135781 ccttgcgttt ccttctgtgg tagttcctat tctatcattt cagcctgaat aatacaatca
   135841 agaccgccta aaaatatttt tcaggcatac tacttgctaa atcgcaaaaa ctcggataaa
   135901 ctattgatct gtaatctgtt aatctgcatt taattagatg aggaacacag aaaaatggaa
   135961 aataaagaaa aacacctggg aagcgtccgc cgcgaggaag ctccaaagag caggaagcgg
   136021 gatgaggaga aggaaccgtt cagctggaag aaggaaattt taagctggat tcagattctg
   136081 gctgcggccg ctgtgatcgc atacgtgctg actacctata ttatagccaa cagcaccgtg
   136141 cctaccggat ccatggaaaa taccatcatg tcccacagcc gggtactggg ctccagactt
   136201 acctataaat tcagcgagcc tgagcggggc gatatcgcca ttttccgcta ccccgacgac
   136261 aaggaggagg gaatcaccac ctactatgtc aagcgtatca tcggtctccc cggagagacg
   136321 gtggatatcg tagacggaaa aatctatatc aacggatccg acacgccttt ggacgagccc
   136381 tatctccacg aggagatgga catgtacgga aaagatcatc tccactacaa cgtgccggag
   136441 ggacattact tcatgctggg agacaacagg aataattcca acgacgcccg gttctggaaa
   136501 aacaagtacg tcccagaaga ggatttgatt gcaaaagttt atctggaata ctttccaaac
   136561 ccgcattttc tccactaact gtccggagaa ctgcgaacta tttttatgat gttacgagcc
   136621 ggcaggaacc atcggccggc aggaggagaa agataaaatg aacaaggtag taaaattcgg
   136681 cggaagctct ctcgccagcg caaagcagtt taaaaaagta aaggacatta tcatggcgga
   136741 caaatcacgc cgctacgtga ttccctccgc tcccggaaag agaacaacta atgacgaaaa
   136801 ggtgacggac cttctctacg cctgctacag cgcagcgtcc gaaggccgca gctacaaaaa
   136861 gattttcgac gccatcacag cccgctacga gcagattatc accggccttg acttaaacgt
   136921 aaatctggat tttgaattta agaccattga ggagaacttc ctggccaaaa agggacgcga
   136981 ctacgcggcc tccagaggcg aatacttaaa tggcattatt atggctgcct atctgggata
   137041 tgaatttatc gacgcagccg acgtgatctg cttcgacgca gacggttcct tcctgtccga
   137101 gaagacaaac caggagcttg cagcccgcct ttccaaggtt tcaaaggccg ttatccccgg
   137161 cttctacggc tccatgccgg acggctccgt gaaaaccttc tccagaggcg gttccgatat
   137221 caccggctct ctggtagcca gagccgttca cgcagacctg tacgagaact ggaccgacgt
   137281 gtccggtttc ctggtagcgg atcccagaat tgtggataat ccggaaccca ttgagaccat
   137341 tacatacaga gagcttcggg agctgtccta catgggcgcc agcgtacttc acgaggaggc
   137401 cattttcccg gtcagaaaag agggcatccc gatcaatatc agaaacacaa accgtccctc
   137461 tgatccggga accatgattg tggagagcac cttaaagcgc cctcactaca cgatcaccgg
   137521 aattgcggga agaaagggct tctgcgccgt caacattgag aaggccatga tgaacgcaga
   137581 gatcggcttc ggaagaaagg tgctggacgt atttgaaaaa tacggcatct ccttcgagca
   137641 catgccgtcc ggcatcgaca ccatgagcat tttcgtacag cagagcctgt tcgaggagca
   137701 tgagcagtcc gtcatcgcag gcattcacag ggcggtggag ccggatcaca ttgagctgga
   137761 ttccgacctg gctctcatcg ctgtcgtagg acggggcatg aaatctgccc gcggcacagc
   137821 cggaagaatc ttctcagccc tggctcacgc cagagtcaac gtcaagatga tcgaccaggg
   137881 atccagcgag ttaaacatca tcgtcggcgt gagaaacgag gacttcgaga cggcggtcaa
   137941 agctgtttac gacatcttcg tcacagcaga gatttagtta tttttcagag gggcgcttgg
   138001 tttcaggcgg aaatttgaga caaaaagaag ctttttagat tggcaaacat actaaaaagc
   138061 ttctttttta ttggttttat taaattattt tcttttttag gaggtcataa cgattgattt
   138121 taaatttagc cgcttttttt attattcccg gatacaccct cctgtttatc aggaatttca
   138181 acctgttctc cctgaacttt tccgtcatcg gaaatatgct ggggagaaag cggggcttct
   138241 gcctgtgggg aatgatgacc ggatggtact tcttctgggt tctgtccagg gtatctgccc
   138301 acctaaagct ttccagaggc gtccggtatc tggtccacac ggcgcttttt ctgctgttct
   138361 gcgccgtcac cacgccctat ctgccggaag aactgccttt taaagccttc ctccacatcg
   138421 tgttcgccat ggccgccgcc ctgtgcctgt gcctctatct gtttctcgcc gcctggcggc
   138481 tgcgaaagga ggacaggaca gccggactgg ttacgctgtg gtgtctggca ggcattctcc
   138541 tcgtgtctgc cgttctgctg attctggtgg gaattgtcag cagcgccctg gagatcttct
   138601 tcaccttctc cacagtattt ttgagccgtt acctctatgg aaggacgaaa cggcttattt
   138661 ctcaatctcc ataatcatgt ccacgcgtct ctgatggcgg ccgccctcaa actcggcgtc
   138721 cagccactcc tccgtaatca tcttggccag ctcgctgcct accacgcggg ctccgaaggc
   138781 caggacgttc gtgttgttgt gcattctgga cagcttcgct gtgtagggat cgctgcagac
   138841 gcaggcgcgg attcccttta ccttgtttgc ggccagggag attcccactc ctgttccgca
   138901 gatagtgatt cccagatccg cctcgccgga cgctacggcg cggcctacct tctcgccgta
   138961 aaccgggtag tcgcagctct ctgtggaatc ggttcccata ttgattacct cgtagccctt
   139021 ggactctaca aactccttga taatgttctt aagctccact gcagagtggt cgtttccaat
   139081 cgcgattttc ataactcgtc tctcctgtct gatttcgttg atttgtttta ttgctttatt
   139141 tttttatttt atttaatttt tctgttttgt tctgtttttc tgttcttcct tatttcctag
   139201 aattctgtgg tctttctcac attggattcc agcaggcggt tgtagcccag ccagccgtta
   139261 ttgtccccgg ctccggctat aatctcgttc atggtctcca gcttggcgtc cgcattgtct
   139321 gccaggctta atgccacagc ctcaaacaga gccggcttct tcggggatcc gtactccagc
   139381 tctccgtggt gagccagaat gcagtgcttc agctctgcgg ccagcttttc cggaaatccc
   139441 ggaatctccc tgatccgctc cgataccatc tctgtgccga tgataatgtg gcccagaagc
   139501 tgtccgtcgt cggtgtagtc gttttctggg aaagcggaaa gctctctcgt cttgccgata
   139561 tcgtggaaca gcgccccggt gagaagcaga tcccggttca ggcgaggata cacagccgca
   139621 aaatagtcgc acagcttcat cacgctcagc gtatgctcca aaagtccccc cacaaagccg
   139681 tggtgaacgc tcttggccgc cgagtggaag cagaagcggc ggacaaaatc agaatcctcc
   139741 acatagtagc tggaagccag ctttttcaga taaggattct tcatggactc aattaacgcc
   139801 ctgagttcct ggtacatggc cttcacatcc ctggagctga ccggcagata atcgctctcc
   139861 gtatactccc cctcgtcggc tctgcggatc cggcgcacat tgacctgatt ggccccctgg
   139921 aacactgtga tatctccgtc aatatacaca tagtccagcg tctcgaagtt tccgactccc
   139981 ggagagccca gatcccagat tttcgcatcc acggttcccg tcttgtcctg cagcgtcagc
   140041 gccccgtatt cctttccatt ctttgtcagg gcaatctgct tcttcttgca gagatacaca
   140101 tcggaaatgt gcatgccgtc gtggaactgt ccaatatatt tcatgtttta tcctctcact
   140161 tctcaaagtt gtctcattta tgtttcaatc ctgccggttt cagcctaccg ccctctcacc
   140221 gtcacctgat actccagaga cgtgtaaccg tcgcggcctt tccgcatcac agtaaccgcc
   140281 gccgcatttc ccagctgaaa gctggcaatc tgtgtgctca gctccttcag agtagccaca
   140341 tcgcggccgt cgaactgcac gataatatcg ccgttctgca gtcccgcttc ataggcaggt
   140401 ccccctgaaa cagcgtctgt aatataaacg cccttgggga ttccctccgc ctgcatggtc
   140461 tcgctgacct cctgtccctt aatgccgaaa taggcggtct ccgctccgtt tgtcatcttt
   140521 tccaggattc ccttgtaatc ggaaatgctc atcaccgact cggagacaat ggaattttcc
   140581 cccttcaggc tgttgtctgt ccagccgatc atctcgccgt ttaaattcag aataaacgtg
   140641 cctgcgtctc cattgctggt caaatctgta aacaggatcc tggacactcc gtctgtcacc
   140701 ggcacgtttc tggccacata ggtaatggct ccgtatacgg aagagtggac catgcctgcc
   140761 ggcgcgccca cgccgattac catatctcct gccttcacag aataggaatt ccccagagga
   140821 atgacctgta tctctccccg aagctccgaa tccaccgcag cggcgtccgc cagcaccaca
   140881 gccatgccag tcacgctgtc attctggaga accgaggctg gcgcctccgt tccgtcaaaa
   140941 aattccacac aaatagaatc cgcctgggac acagccgaag atctggtcag aataatataa
   141001 gaactgcttg tcctggcaat cacggctccc gcgcagtagc cgctggtctc aatgggattt
   141061 ccaaacagat ccgtctgctg catcccggaa tgtacggtga caatacctcg atctgcctgc
   141121 tgctccaccg cccgcacgct gtcgtacatg gattttaaat cctccgaggt aaactcatag
   141181 gtttccatat aggctttcac cgcctcgtcc accggaaccg tctcctccag cccgccggac
   141241 tcctgcacag atccgctctc ctccggctgc gcctccggat catctctgtt aaattctata
   141301 gcggtgctct cgccacggga actatcctcc catctgtcct ttgaccacga tctgactgcc
   141361 gtaaagctca gagccgacac agccccgaac gcagccgcag ccagaagaaa tacagccgcc
   141421 cgcgccgcaa tctgcctcct ggtcagagga ggcttcacga tcttttcccg cataaattca
   141481 cgcctgcggg gttccttttt atcaggtcct tcggtatctg acatcattct tttcccttca
   141541 tgcttcttaa tttcaggaac acatatatgt attatacgtt tcttctaaga cgattgcaag
   141601 aatattgtgg gaaaatcgcc gggcggcaaa ctcattgatt ttcttttgta aaaaagaatt
   141661 accgccatct ttttcctaat ctctgcagcc gaagctgttt taacagaaca agacgcacac
   141721 tgttccaggc aatgaaactg cggtttacta ttgagagttt taaatagcgg cagtaaaact
   141781 ttccctcttg tatccttcgg ccggatatgt tatattaaac atagaaaagg gaagccacag
   141841 aggcggcctg cccctcaata acttataact ttacatcttt acgatatcag ccgtcagcta
   141901 gtgcgaatag ttggcggcta ttttctatcc ttaaaaatct gatataacag actaataagg
   141961 gaaacaatga ataaacaaaa ctgaaataat tcagaatatg taaccattgt atcgccctcc
   142021 tttcttccgt ctggagggct tttataccct ccgaaaataa gagagtggcc gcccggctct
   142081 gtggtttccc atatcgacat tatatagcaa tcttccttat ctgaccatca ttgtttcgcc
   142141 agggagacag cagaacgaac ctctgcagcg gcccatttct ccatatcatc tctgctcata
   142201 ttttccatca gaaacttctt taaaaagcaa atttacgctt cccctctctg ttccagctgt
   142261 tcaaacacct catccatatc catttcaaac atggcgctgt ctgcctggac tggggaaaaa
   142321 tagaaggcga cgttttctgc cccgaattcc tgttccagct gctcccactg ggaagtcagc
   142381 ccaatacaga aggccagagt atcgcttccg agggactcca tataccagcg gatctgatac
   142441 ttgggagaga cgtattcctg aatgctcttc agtgtcgtat ccctgtctgt gcagtcgtct
   142501 ccataaggaa ctgatctgct gacgccgtcc tttttcagaa aaatatctat cccccgctct
   142561 ttctctgatt ccacgcattc aaactgaatt ttatcctcgt ccggcagttt tttattgaaa
   142621 tagttgataa tggaatcgtc gaagtcccgc cagtcaatcc agatcagctc gccgctgtcc
   142681 caaaattcat cttttgtatc atccggcgct tctaaaagct ttcttatttc ttccaattgc
   142741 ataccctccc aaatccttcg ctatgtgtct aactggaaaa catacatttt ccctgtattt
   142801 gtgttatttt ttctcccgct ctcttttttc cagaatgacg ggaggaattt cagcaaatct
   142861 tctcaggaga taagcctttc ccttctcccc tctccattta tgacaaaacc aaagcacgct
   142921 gcagcaaaaa agcgccgctg caatcaggaa tggatgatga aattctgccc tgcccagaat
   142981 cgcatagctt atcaaagcgg aagccgcaat ggcgcttccg gctatgccca gggcaatttt
   143041 tattactttt tcctgggaca gctccagaaa ataattgtcc cattcttctg aattaaattt
   143101 cagctgcctg cctttgatcc agaacagaat aagaactaaa cctaacgcaa tccccttgct
   143161 gaaaaggacg tttatcactg ccgaacctgc taaaatgatc agtttttcca tgatttattc
   143221 cccttatgtg tttttaaaaa ttctatcgtc ttctttgcta tgacaaccgc gcacagaaaa
   143281 cctgctatac cgcagataac cgcgtctgtc ttatctgcca cgccgcctgt acggcgcatc
   143341 ccataataat aaacagtcca tatcagtatc agcacagagc cgctgatact gtgccaaaaa
   143401 gatttcctat tcatatcacc gcctcatctt tctcactatc caacagtaag cggccgctgt
   143461 tccggccgga atcaacgcca gataactgac aatgttaaaa agcgtgaaat tataggtatt
   143521 agacacctct ccaaactcca gaagatatcg gcagcccatt cctatggcag tgatgagaaa
   143581 cgtcgttatg taaacctttc ttcccctgcc aggcccgaaa attccagctg acgccagggc
   143641 aatcacgccg tagcttgaca ccagcagata cactccgcta aaatccagag gaaacggttc
   143701 gctcctgata ggaaatacaa agcagcctgc aaagatgata taacccataa gcaaaattcc
   143761 tggcagctga gaatgtttct caaaaaaata ctggagcctt ccgcttttca ccccaaagta
   143821 aaccgccgcc gcaaaaagcg ctgtcacaac tagaatcgtg ataatataaa ccgctgcaaa
   143881 tgccatcttc ctcccccttt cccccactct attcaatcct tacacgaacc gggccgattg
   143941 taagatttcc tgctcccgct gccgtgtacc atcttccttt ttccagtcga atcttttccg
   144001 gcgcgccagg cgtaatatac cctatctcat atctttcccc agtttcaaca tcagtaaaga
   144061 gcacactcgt atcacagtct ccgctcacct tcaccgttcc aaacaggggc tgtatctgtt
   144121 ctgatttaat ccctccatca ctgcccgtca gagtaaaagt atagttcctt tgaataccaa
   144181 tatgaagaaa aactgcggct gtcaatatcg cggcaataca taaaatcagc tgtttctttt
   144241 tcactgtgtc acctgctctg tatccttcgc cagcttcctg aaaatgatta ttcttactat
   144301 gacacaggcc attatcactg cgaaagacaa gatcccatac aataaagctt ctgtatacca
   144361 gggagccgaa taggcagcat atatgtccgg atacctttta tagctgtaaa aatcaaatcc
   144421 tgttttcaat gcaatgacgt ataagcttcc atagataaca
//
LOCUS       DBMDUW010000002        99616 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_272_length_99616_cov_4.170296, whole genome shotgun sequence.
ACCESSION   DBMDUW010000002 DBMDUW010000000
VERSION     DBMDUW010000002.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 99616)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 99616)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..99616
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_272_length_99616_cov_4.170296"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            1..413
                     /locus_tag="ACZPCR_00745"
                     /pseudo
     CDS             1..413
                     /locus_tag="ACZPCR_00745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008751007.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="type I restriction enzyme endonuclease
                     domain-containing protein"
     gene            472..711
                     /locus_tag="ACZPCR_00750"
     CDS             472..711
                     /locus_tag="ACZPCR_00750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016441137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3791 domain-containing protein"
                     /protein_id="HIR1229449.1"
                     /translation="MALHENIKNSRELEFAVFCIENIAARLGVNAERVYEAFTEKSDI
                     LNGYIVPEYEILHTQSKEYIVEDLLDVMKERGVEV"
     gene            708..842
                     /locus_tag="ACZPCR_00755"
     CDS             708..842
                     /locus_tag="ACZPCR_00755"
                     /inference="COORDINATES: protein motif:HMM:NF024550.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3990 domain-containing protein"
                     /protein_id="HIR1229450.1"
                     /translation="MILYHGSYLEIAEPDLVHSRLNVDFGRGFYVTPLYEQAEKWCGK
                     "
     gene            832..999
                     /locus_tag="ACZPCR_00760"
     CDS             832..999
                     /locus_tag="ACZPCR_00760"
                     /inference="COORDINATES: protein motif:HMM:NF024550.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3990 domain-containing protein"
                     /protein_id="HIR1229451.1"
                     /translation="MANDKVFNTVELFFERLIDKAEAISRLRYEKPNLQICFRTEKAL
                     GLLHFEGSEQV"
     gene            996..1208
                     /locus_tag="ACZPCR_00765"
     CDS             996..1208
                     /locus_tag="ACZPCR_00765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016441135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3791 domain-containing protein"
                     /protein_id="HIR1229452.1"
                     /translation="MNANPILLQKKYSRVIECFAREQGISLDAALDFFYHSQVYQLIR
                     DGISDMHCMSDAYLAEELEQEYQGKD"
     gene            1223..1696
                     /locus_tag="ACZPCR_00770"
     CDS             1223..1696
                     /locus_tag="ACZPCR_00770"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009247292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HIR1229453.1"
                     /translation="MIKILFICLGNICRSPMAEFVLKDMAARRGLASKFYIASAATSA
                     EELGNPVHRGTREKLRACGISTAGKYAVQMKRQDYEDYDYLLGMEERNLSNMRRIAGG
                     DPDGKMYRLLDFSPNPRDIADPWYTGNFDLTYDDIVEGCEAFLEFLAKEHPETFR"
     gene            complement(1746..3065)
                     /locus_tag="ACZPCR_00775"
     CDS             complement(1746..3065)
                     /locus_tag="ACZPCR_00775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HIR1229454.1"
                     /translation="MIETLVLAGFLGCLILCLAAGFSLVYALLGGLLLFTGYALYQKI
                     NVRDIVRLLCIGIKKSGNILIIFALIGFLTALWRACGTIPFIVYYGMKIMNPSFFVIS
                     VFLLCCLVSFLMGTSFGTASTVGVICMILARLNGISPTLTGGAVLSGIFFGDRCSPMS
                     SSASLVASLTETKLYDNIKRMFRSCLLPFVLTCLLYLVLGKSGGSASGTESLMEEFPR
                     LFALPWYTSVPAAVILIFCMMKWDVKAVMALSAGLSFLLCVFVQQMAPSAVLSAMMLG
                     FHPEGDSELIPLISGGGFLSMVEVSLIVMISSSYLGLLDETGLLTNIQSLIRRLSGKL
                     GRFPAVCTASIVTSMFSCNQTLASMLTCELCKGEYEKPEDLALDLEDSVILLAALIPW
                     SIAGSVPLAAIGAGTASFFFAFYLYLLPLYRCVKEWAEKRRKRASAV"
     gene            3336..4619
                     /locus_tag="ACZPCR_00780"
     CDS             3336..4619
                     /locus_tag="ACZPCR_00780"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004608432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase Y family protein"
                     /protein_id="HIR1229455.1"
                     /translation="MKTADETAAPVVFHVDVNSAFLSWEAVYRIRELGAKKDLRDGLC
                     AVGGDRQARRGIILAKSQSAKGYGVRTGESILEAKRKCPDLKLVPANYHLYRQSSEAF
                     IKILKEYSPEVEQYSIDEAFMNMTGMEKLFGPPREAAERIRERIFRELGFTVNIGIST
                     NKLLAKMASDFKKPNLVHTLFPEEIPEKMWPLPVRELFFVGRSTEASLKRLGIRTIGD
                     LAKTDPELLKYHLKKHGEVIWNFANGRDAGVIETEETENKNYGNSTTIPFDVTDEGTA
                     RIVLLSLAETVGRRLRAGHVKAEGISVTIKNTDLHSVSHQAVFETPTNITEEVYRAAC
                     RLFEELWDGSAIRLLGISTSRIKEEGCARQMNIFEGEKYEKLERLDHAVDEIRSKFGS
                     GAVMRASFLEQPVAHMAGREVRAEKKLDYKDIEIE"
     gene            4647..4889
                     /locus_tag="ACZPCR_00785"
     CDS             4647..4889
                     /locus_tag="ACZPCR_00785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013281537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229456.1"
                     /translation="MKREIVFKMERPGLVEEGQVVEVSESVTPFNVNYMIEPAVAMSG
                     LFQLNNRLKADHGTVKKIEENARGYYVTVEFEEEES"
     gene            4889..5068
                     /locus_tag="ACZPCR_00790"
     CDS             4889..5068
                     /locus_tag="ACZPCR_00790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002576758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4250 domain-containing protein"
                     /protein_id="HIR1229457.1"
                     /translation="MQKIPKDPIMCLSFVNTQLRDAYNSLEELCRAFDVKKEELEERL
                     AAVGYVYQPELNQFR"
     gene            5187..6692
                     /gene="cls"
                     /locus_tag="ACZPCR_00795"
     CDS             5187..6692
                     /gene="cls"
                     /locus_tag="ACZPCR_00795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006770965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HIR1229458.1"
                     /translation="METIFSVWDWIPEHLIFVNLLLSVGIVFFQRRDPRTVWAWLLAL
                     NFIPVFGIIFYLLFCQDYKKNRMFRIKEVEDRLKCPAKLQEDCIKTRDLALLGDLAAD
                     YESLVLYNLDTSGSVLTMNNKVQIFADGEEKFQKLKADLEQAREYIHMEYYIIKNDEV
                     FDSIAPILIRKAEEGVQVRILADGMGGRFMPGSRWEILRQAGVQVGIFFPPVLGRLNL
                     RVNYRNHRKIVVIDGRWGYVGGFNIGREYVSKDPKFGYWRDTHLKLGGEAVLSLQIRF
                     ALDWNYAVGENLFQDARYFELHIPTDRPDMRDESGKISCVHIPEVGIQIIASGPDTMY
                     RQIRDNYLELFHKARKHIYIQTPYFVPDDAVLSALQIAARSGVEVMLMIPCKPDHPFV
                     YWATYSYVGDLLRAGARCFTYEKGFLHAKGVCADGQVCCYGTANMDIRSFELNFEVNA
                     VIYNQKITEQMEEIFINDLKSCREITRETYEARGLVTRFKEQCSRLLSPLL"
     gene            6983..7753
                     /locus_tag="ACZPCR_00800"
     CDS             6983..7753
                     /locus_tag="ACZPCR_00800"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007861949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HIR1229459.1"
                     /translation="MIRLILVASFVIGFLLFFSGVLYRLKKLGQTDWETAEWKSLNIV
                     RRAFSVILKTAGVKVTVKGAEHIPADTPALYVGNHRSYFDILVGYTTVPGLLGFVAKK
                     EMLKIPLLSQWMVQVNCLFMDRQNVKEGLKTILQGIEKIKRGVSIWIFPEGTRNRNEK
                     ETDLLPFKEGSLKIAEKTGCPVIPVAITGTADVFEKHLPFIRPAHVTIEFGEPFFVKE
                     LPPEQKKFPGAYTRDRILEMLEKEQHGLTGDQEAAGQH"
     gene            7713..8840
                     /gene="pheA"
                     /locus_tag="ACZPCR_00805"
     CDS             7713..8840
                     /gene="pheA"
                     /locus_tag="ACZPCR_00805"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HIR1229460.1"
                     /translation="MDLQEIRKQLDSIDAEFVRLFEKRMKLCADVAEFKIRTGKAVYD
                     PKREQEKIAAVRSMAEGEFMKEAVGELFLQMMTLSRRYQYRLMEQVQSASDFGFQRVE
                     DIEKKQVRIAYQGLEGAYSHAAVIQFFGEQADMFHVRRFEDAAKAVFEGRADYAVLPI
                     ENSSAGAVSDNYDLLLKYENYIVAEVFVPVCHCLLGTRDAELSDIRTVLAHPQALMQS
                     SQYLNAREDWRQLSVENNAVAARKVSEEADKSQAAVASRTAAEIYGLKVLAEGINHNR
                     ENTTRFLILSKHPVYRKDADKVSICFELPHESGTLYNMLNNFAFSHLNMRMIESRPIP
                     GRNWEYRFFVDIEGNLDDPDMINALKGIAGEANHMRILGNY"
     gene            8995..10359
                     /locus_tag="ACZPCR_00810"
     CDS             8995..10359
                     /locus_tag="ACZPCR_00810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1229461.1"
                     /translation="MKQHLILYRNLKYGELLDRMGGLLEQYGGAAQEAAGQKETGQEA
                     GGQETAGQKADGQEAEEAWCAGELIALADAYGFEGNLWLCFLALCLAENENPYSIACE
                     IRGEASGSLNQLALHDFSVFWQLSRQDLGTLPMKEVWSLAADYHGPGKKSRQFDSRVR
                     DRILTLAAELLQAESPEDFRGRTAEFYRELGVGKFGLNQAFRVTGAEGNAQIEPITGV
                     EEVSLKDLVGYERQKKKLIENTEAFIEGREANNVLLFGDSGTGKSSSIKAVLHEYYGR
                     GLRMIEVYKHQFQCLGEILEQVKDRNYKFIIYMDDLSFEEYEIEYKYLKAMIEGGLGR
                     RPDNVLIYATSNRRHLIRGKFSDKRELDDDLHQNDTVQEKLSLVARFGVTIYYGAPDK
                     REFQQIVRALAARHNLCMPEEELLLKANQWELSHGGLSGRTASQFITHLLGTEQIQEE
                     SYGN"
     gene            10349..11914
                     /locus_tag="ACZPCR_00815"
     CDS             10349..11914
                     /locus_tag="ACZPCR_00815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA phosphatase family protein"
                     /protein_id="HIR1229462.1"
                     /translation="MAIKMFAAIDVGSFELEMGIYEISQSFGIRQADHVRHVLALGRE
                     TYNDRKISYRLVEEMCQVLKGFSEIMKSYRITDYRAYATSAMREAKNSQIVLEQIRVR
                     TGLTVKSINNSELRLMTYKAVASKDAAFHKIVQKGTAIIDVGFGSTQISLFDKDTLVS
                     TQNVVLGGLRIREMISHWNLSPRETVPVIEELVDNELYPFRRMYLKDREIKSLIATGE
                     SILFMARSGIRHMESDRVSAEQFKSFYRKLLSMTAEEIEDEFGIDGEYASILVPSAVI
                     YGRILEMTGAETVWIPGVSLCDGMAAEYTQDRKLVKLRHDFNGDILSSARNMAKRYKC
                     HGDHIQEVERLSAELFDVTKKYHGLGERERLLLRIAAILHDCGKFISSSRETQSCYQI
                     IMATEIIGISHLEREIVANVVYYYNQDFAYDAVKLESDLSQYEGSGLTRRAVTILIAK
                     LTAILSLASAMDRSQRQKFAGASMAVRDGKLLITASCPETIILERASFENRAEFFEEI
                     FGLQPVLKHKRRV"
     gene            11917..14061
                     /locus_tag="ACZPCR_00820"
     CDS             11917..14061
                     /locus_tag="ACZPCR_00820"
                     /EC_number="2.7.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006778444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009358 - polyphosphate kinase complex
                     [Evidence IEA];
                     GO_function: GO:0008976 - polyphosphate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006799 - polyphosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA degradosome polyphosphate kinase"
                     /protein_id="HIR1229463.1"
                     /translation="MAEGNERFWESKNYVNRELSWLDFNWRVLGEAKDKTTPLFDRLK
                     FLSITASNLDEFFMVRVASLKDMIHANYTKRDIAGLTAAEQLTAIEAKTHQLVEEQYH
                     VYSRSLLPALRQNGLNIIASHENLTKYEGTYVDSYFEEMVYPVLTPMAVDSSRPFPLI
                     RNKSLNIAALVKKKKGDSELDFAMVRVPSGLPRVVVIPPEEGKEKAGISVIFLEEIIE
                     RNIEKLFLNYDIICSHPFRVMRNADLSIDEDEAEDLLKEIERQLKKRQWGEAIRLDIE
                     EKADKRLLKILKKELKVTNDEIYEIGGPLDLTVLMKVYGLPGFDRHKAPGYTPQPVPA
                     LMNEDDIFTNIRKGDILLTHPFETFEPVVNFIKKAARDPEVLAIKQTLYRVSGNSPII
                     AALAEAADNGKQVSVLVELKARFDEENNINWAKMLEKAGCHVIYGLLGLKTHSKITLV
                     VRKEEDGIRRYVHLGTGNYNDSTAKLYTDCGLFTCSRQIGEDATAVFNMLSGYSEPLG
                     WNKLSLAPLWLRGKFLRLIQREIKYAKEGKTARIVAKMNSLCDKEIIANLYEASCAGV
                     EIKLIVRGICCLKAGVPNLSENIEVRSIVGNFLEHSRIFLFENGGREEIYMGSADWMP
                     RNLDRRVEILFPVEDEALKARLIHILDVQLADNVKAHLLQPDGTYKKKSLRGRQKVNA
                     QEQFCAEAIEAARAMEESADPRNRRVFIPMEQ"
     gene            14187..14891
                     /locus_tag="ACZPCR_00825"
     CDS             14187..14891
                     /locus_tag="ACZPCR_00825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008724114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIR1229464.1"
                     /translation="MSEINILVVDDEKEIAELVEIYLVSDGYRVFKAENAREGLEILE
                     KENIHLVLLDIMMPGMNGLEMCRKIRETNNIPIIMLSAKSTDLDKILGLGTGADDYVV
                     KPFNPLELTARVKSQLRRYTQLNPQSSVIQAAKNEISIKGLVINKDNHKVTVYDEEIK
                     LTPIEFDILYLLASNPGRVFSTDEIFEKVWNEKVYEANNTVMVHIRRLRGKMKEDTRQ
                     NKIITTVWGVGYKIEK"
     gene            14896..16017
                     /locus_tag="ACZPCR_00830"
     CDS             14896..16017
                     /locus_tag="ACZPCR_00830"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1229465.1"
                     /translation="MSRRFRTRTVTNIFYATLLTCLIEIFLIANVSMVEEYLRKIESE
                     SFLLDFLELSPIMVLIYVLIGIGIFSVIFLRLQERHLRYLARISAAMQDISEGDLNTV
                     VEVKGDNEFSAMAVNLNRMVEDIRRLMDKERESERTKNELITNVAHDLRTPLTSIIGY
                     LELLSGKVELPREMEKKYIDIAYAKSRRLEKLIEDLFGFTKLNYGKLSMNVGKVDIVK
                     LLEQLLEEFYPNFAEKNLSYELHSNLPSKVIDADGNLLARLFDNLINNAIKYGADGKR
                     VLVQIQAEEEIVTVSVTNYGYVIPENELPLIFNKFYRVEQSRSTHTGGTGLGLAIAKS
                     VAEMHGGSIQVKSDLDGTVFTVKLKTHFDINREQFEVAE"
     gene            16121..18634
                     /locus_tag="ACZPCR_00835"
     CDS             16121..18634
                     /locus_tag="ACZPCR_00835"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229466.1"
                     /translation="MGKRAGGKALPALFLILCLLTAVLWQTPFASLAKAQSSDVKEEQ
                     DSEEGAGDRLKRQVAMEADYGFGKKAKAGRYLPIQVTYKNQERQAFSGTLKILTMESS
                     KEVYQYEYPVDLGAGEETEKEYYIPLGVGNDQMFLTLTDQDGNEIIKKRLKLDIPSEA
                     ALLFIGVLSDHPDSLSYLDGCGLSYGTLRTSVVPLSGGEVPENQLGLDQFDLIAVNDF
                     DWNSLTHGQEKALLSWVREGGTLLFGTGEQLERTLGRLKKDLIGETPVSNLARTVDLM
                     KLLGENGGEALSAELFCSDFSIKGGRKALFQEGTALLTRKTEQQGQMVLAGFDLADVS
                     GQFLQKPSLAEKFLTEVMGENTVQYLAQDQYYGLSSLYYSIQALINTGNVDRLPNLGL
                     YTAVILLYIILIGPGAYLYLKRKSLQNYYMLSVAVLAVGFTGIIYAAGAKTRFAAPFF
                     TYVTVENYGKEELESETYVNVRSPYNTPYTVELNPDYLVRPITKNYYYESNHPVTFTG
                     NEKFETAVRIEPSQTRIKVRDAAAFEPKLFSLKREERSDRPAPSGTIRFFDGQVTGTV
                     VNHSEETLKNAVLLLYGKAVFLGEMKPGEEKILDGLPQLSYPSAYKTAVAQMVPGTDQ
                     YTKTDISDKNYMEAQSQTKLLSFYMESRMAEYFPEARLIAFSSGEEETDFLADRYYVT
                     GGLTLMTSELPVEQGKDGMVYRCVLEQLPTVLSGVYDYQGNSLYTGEPSEPLVLEYHL
                     GNDLEIERLTFDWLSPEFIDNPKYPYLEQFDGSIYFYNYSTGKHDRMDLSKKEYSREE
                     LNPYLSPSNTLTVKYAGEPGEDDIWNMILPVPYVTGREK"
     gene            18634..19596
                     /locus_tag="ACZPCR_00840"
     CDS             18634..19596
                     /locus_tag="ACZPCR_00840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002568907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1229467.1"
                     /translation="MLEIRDLRKKYGNFQALDGLSMTIEKGELFGFVGPNGAGKTTTI
                     KIITGLLQPDSGSIVIDGMDGIRDRRHLKQKMGYVPDSFGVYDNLKVSEYMEFFASCY
                     GIEGLESRKRCGLLLEQMKLEDKADFFVDGLSRGMKQRLCLARALIHDPELIVLDEPA
                     SGLDPRTRLEFTSILKELREQGKTLLVSSHILSELSEMCTSIGIIEQGRMALSGSMEQ
                     ILERVNSSNPLLITIFKGREKAMSILRSHPCVQTISVKGEEIKVGFNGDKKDEALLLQ
                     QMVDAEVMVNGFMREKGSLETIFMQITDHMGEKAVLVHEDESGL"
     gene            19574..20512
                     /locus_tag="ACZPCR_00845"
     CDS             19574..20512
                     /locus_tag="ACZPCR_00845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1229468.1"
                     /translation="MKMNPVYKRELKVGSRSIRMAVILLAFNGILSAVALFNMYSAVE
                     QVKMTAEIQYSRFLQLYVFVASLEFIMLMFIMPALTSNSISGERERQTLDLMLTTTMK
                     PGEIVLGKLAAAFTTMLLLVLSSFPVLSLVFVYGGITVTDMAQLMLCYVTVALLSGAV
                     GVFFSSMFKRSTLANVCAYVTIIFLVAGTYGANIFAYQMSQNEISSYMDAVDNIAKQA
                     SSGGSIYMLLFNPAVTFYAMINQQAGDSDVAGTLERMFGAHPQNFVLEHWTEISIAVQ
                     ILAAVLLIAAAVAAVTPVWERGRERRRGKDKNSRPI"
     gene            20579..21412
                     /locus_tag="ACZPCR_00850"
     CDS             20579..21412
                     /locus_tag="ACZPCR_00850"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003906 - DNA-(apurinic or apyrimidinic
                     site) endonuclease activity [Evidence IEA];
                     GO_function: GO:0008081 - phosphoric diester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HIR1229469.1"
                     /translation="MLRIGCHLSSSKGYLAMGKEAEKIDGGTFQFFTRNPRGGKAKEI
                     DPEDVKAFLDFAGQKDIAPILAHAPYTLNGCSADEGIRAFAVNTMADDLKRMEFTPGN
                     LYNFHPGSHVKQGVEAGIAYISDMLNQILRPEQTTTVLLETMAGKGSEVGRNFAELRE
                     ILDRVHLNEKMGVCLDTCHVWDAGYDIAEHLDQVLDEFDRTIGLSRLKAIHLNDSQNP
                     LGAHKDRHARIGEGCIGLEALVRVINHPALRTLPFYLETPNDLDGYAREIALLKSRYI
                     E"
     gene            21622..23019
                     /locus_tag="ACZPCR_00855"
     CDS             21622..23019
                     /locus_tag="ACZPCR_00855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019162461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015851 - nucleobase transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-xanthine permease family protein"
                     /protein_id="HIR1229470.1"
                     /translation="MSEKETKGAEYDFYGKLPLCKAIPLGLQHVLAMFVGNLTPLLII
                     TGACGLTNTQEFANLQVDLLQNAMLVAGIVTLVQLYAIGPVGGKVPIIMGTSSGFIGV
                     FNSVVGVMGGGILSYGAIMMASILGGIFEGILGFFLKPLRRFFPALVTGTVVLSIGLS
                     LIAVGVNSFGGGDKAADFGSVENLLLGTLVLVVIVALKHGTKGMTSSSSILIGIIVGY
                     IVAAIMGLVLPTTGVTAEGVEYTKAWVLNWDKVAEASWFSMPKLMPVKPVFDWRAVIP
                     VMIMFVVTAVETVGDISGVTEGGMGREATDTELSGGIICDGIGSSFAALFGVLPNTSF
                     SQNVGLVAMTKIVNRFALATGAVFLILCGLFPKLAALISIMPQSVLGGAAVMMFSSIV
                     MSGIQLITKKSLTPRSITIVSVALGLGYGIGANSGILSHLPQSVQLIFGGSGIVPAAL
                     VAIILNVLLPAEKEE"
     gene            23212..23775
                     /locus_tag="ACZPCR_00860"
     CDS             23212..23775
                     /locus_tag="ACZPCR_00860"
                     /inference="COORDINATES: protein motif:HMM:NF014069.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HIR1229471.1"
                     /translation="MRREKLERIFPAFQEIQDETLRVKSEEAMLAAMEAGGWNEQTIK
                     LCPVTLNWENCDVSWTEHVSDVTSMCLMEFDGLEKYYKRHGVSFSRDLVAAGALLYDI
                     GKLTEFVFRDGKAVHGDNFELMRHPLSGAVIAAKAGLPDELVHLIAVHSFEGDKSYQT
                     AESEFVRSIDIFVFNCSVKGLKKIHKN"
     gene            23813..24841
                     /locus_tag="ACZPCR_00865"
     CDS             23813..24841
                     /locus_tag="ACZPCR_00865"
                     /inference="COORDINATES: protein motif:HMM:NF015366.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter substrate
                     binding protein"
                     /protein_id="HIR1229472.1"
                     /translation="MKKTLKTALVLTAIGALALTGCSGKSGDSSNQKKEAAEGGGAGE
                     WTPERSINMIVPWSAGGGSDLAVRTLVPYLEEDLGVSITVLNSTGANGWIAWNDLLKA
                     DPDGYTIAQMNIPTVYSGYLDPQQNRDETLDDFTLIANEISDWGCLVVKAGDERFPDV
                     ESFIEYGKSNEILAGDNGVGTNKHLVAENLKSQIEGLQITPVHQAGWSDTYAALLGGH
                     IDVGWGSIGETIQAYEDGEVDILCVFATERSSLLPDVPTFNELMPEYDVVSPSDRGFA
                     LPAGVDDAVYDRWVQAMDNCINNPEFIEKMAELGQAVNYMGGEEYTAYAKEQEAEMEK
                     FSDILGWK"
     gene            24873..25307
                     /locus_tag="ACZPCR_00870"
     CDS             24873..25307
                     /locus_tag="ACZPCR_00870"
                     /inference="COORDINATES: protein motif:HMM:NF018979.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter TctB
                     family protein"
                     /protein_id="HIR1229473.1"
                     /translation="MKLKQIHAEVWLGGILIILAVIFYIMAGQFPNASAAVWPKAVLI
                     GIMILSVLLVIHGLQMTKDADGNADLGGAVLKGPMASLVMIVAYAVCMSFTGYFVSTA
                     IFLPLGMAALGQRNWKAILGVTVGLELFVWFLFVVQLQLRMP"
     gene            25334..26830
                     /locus_tag="ACZPCR_00875"
     CDS             25334..26830
                     /locus_tag="ACZPCR_00875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007862712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter permease"
                     /protein_id="HIR1229474.1"
                     /translation="MIQEILQNFMSIQVWIGLVVGVVGGMVVGAMPGLSGGMAIALLL
                     PVTYSMDPVAALVMLMAIYTSAMTGGSISAILLHTPGTPANAATAMEGYPLTKKGRGL
                     EAVGMSMLSSGIGGFASALALLVIAPPLAKVSLMFSEPESFLISVFGLTVIGSLAGNS
                     ILKGLLMGLVGLFLATVGMDSVTGTLRYTFGFDSLMNGIQMVPALIGLFTISQVMSNC
                     EDYKHANQSILEKSNATLGKKMLPTLKEIPRYIWNWVSASIIGIVVGILPGAGGNIGS
                     WIAYDQAKKHSKHKEEFGNGSLEGLASCEAGNNAVTGGSMIPLMTLSIPGSPNAAIIL
                     GGLLIQGLVPGARLFTTQAPTTYSILVGFALSNILMVFVGLAIARYVVNVTKIPNSIL
                     MPVVVSLALIGSYAINASMFDVFVAIFFGFLGYLMNKLDLSSAALILGLILGGTAESG
                     LMLSLVMAKGDPLGYYMGRPICLVLMALILLSVAGPVISKLKGKKEKA"
     gene            27110..27697
                     /locus_tag="ACZPCR_00880"
     CDS             27110..27697
                     /locus_tag="ACZPCR_00880"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229475.1"
                     /translation="MRQQPLQWHPAFQAVMQIELAEYQDWLKYSALPKKENVWLSRLR
                     PGLDVEEDIAMLAQAYQGRDENPLYSAVMELIVRANKKQYEEAKHMCNALRELFAEEI
                     EEGRQRGKAEGKIEGKIEGKEEGHCLAFIEILRRKVENGKSLEESAEALEERPEDIEK
                     LYRLIENQGPDADAELIYQLYRADVKSSEKKEGQR"
     gene            27781..28632
                     /locus_tag="ACZPCR_00885"
     CDS             27781..28632
                     /locus_tag="ACZPCR_00885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012743420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HIR1229476.1"
                     /translation="MKFFKLKRRHVCLQENALFWVFLALLSIGCMAKLYERASLAPAA
                     SESVFASSQAAEGRDYQVKDRKLPIYCVQTEKPQVALSFDAAWGNEDTRQLMEILAKH
                     NVKVTFFMTGGWVEKYPEDVKYIASQGHDLGNHSENHKNMSQLGEAEIRSEIQTVHDR
                     VKELTGQDMALFRPPYGDYDDKVVAVADRMGYYPIQWDIDSLDWKDYGADSIVDKVVN
                     HKHLGNGSIILMHNGAKYTPQALEAVITGLQEKGYELVPISQLICKEQFSIDHEGRQI
                     PSQKAVQ"
     gene            28838..29644
                     /gene="spo0A"
                     /locus_tag="ACZPCR_00890"
     CDS             28838..29644
                     /gene="spo0A"
                     /locus_tag="ACZPCR_00890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005509 - calcium ion binding [Evidence
                     IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0042173 - regulation of sporulation
                     resulting in formation of a cellular spore [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA];
                     GO_process: GO:0051606 - detection of stimulus [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HIR1229477.1"
                     /translation="MAELNIAIADDNRQTLELLGEILEGEKDYHVVGKADNGNEAYNM
                     IMKTRPDVVLMDIVMPGMDGISVMEKIKSNAEMKDSTSFIMVTAAGSENLTAEAFKLG
                     ASYYIMKPFTREIILDKLRRLTGYKNKTTMLSGSRRVKPYVNKAEYMEQNLENDVTQM
                     LHEIGIPAHIKGYQYLRDAIIISVGDQEMLTSVTKILYPTIAKKHDTTPSRVERAIRH
                     AIEVAWNRGEMDTINDLFGYTVSTGKGKPTNSEFIALIADKIRLDYKRIS"
     gene            29764..31209
                     /gene="glgA"
                     /locus_tag="ACZPCR_00895"
     CDS             29764..31209
                     /gene="glgA"
                     /locus_tag="ACZPCR_00895"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007860421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - alpha-1,4-glucan
                     glucosyltransferase (UDP-glucose donor) activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HIR1229478.1"
                     /translation="MKKILFIASEAVPFIKTGGLADVVGSLPKCFDKEYFDVRVMLPK
                     YLCIKESFRNDMKYLNHFYMDYLGQSRYVGILEYVYEGITFYFIDNESYFCGSKPYGD
                     WYCDLEKFAFFSRAALSSLPVIGFQPDVVHCHDWQTGLIPVFLKDKFHEGEFFRNMKS
                     VMTIHNLKFQGVWDVKTIQRLSGLPDYYFTPDKLEAYKDGNMLKGGLVYADAITTVSS
                     TYAEEIKTPFYGEGLDGLMRARAGSLRGIVNGIDYGDFNPETDPLIVQNYSARTFRKE
                     KVKNKRALQQQLGLEQDDKKFMIGIVSRLTDQKGFDLIQCVMDEICTDDVQLVVLGTG
                     DEKYENMFRHYDWKYNGRVSANIYYSEEMSHKVYAACDAFLMPSLFEPCGLSQLMALR
                     YGTVPIVRETGGLKDTVWPYNEYEGTGTGFSFANYNAHEMLDTIRYAKHVFYNRKREW
                     NKIIDRAMAADFSWDSSALKYQELYDWLIGY"
     gene            31240..31698
                     /locus_tag="ACZPCR_00900"
     CDS             31240..31698
                     /locus_tag="ACZPCR_00900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009219084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HIR1229479.1"
                     /translation="MTIYQEITGNQVLMSGVIGWVVAQVLKTIIDIALNKSFNPERLT
                     GSGGMPSSHSSTVCALTTASAFCYGFGSFEFAISFLFAMVVMYDAIGVRQETGKQAKV
                     LNHLLFENPLKLDTVVLQERLKEYVGHTPLQVFAGAVLGIGIAVFMNGFY"
     gene            complement(31746..32456)
                     /locus_tag="ACZPCR_00905"
     CDS             complement(31746..32456)
                     /locus_tag="ACZPCR_00905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005349783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5714 domain-containing protein"
                     /protein_id="HIR1229480.1"
                     /translation="MSTSNTPWECLICGAPLIYLEHQETMKCAVCGGSFSSHARCANG
                     HYICDSCHAKDALDLICQFCLHTELKNPVAIMEQLIDFPQIHMHGPEHHVLVGAALLA
                     AYKNCGGELDLSSALDQMKERGSQVPGGICGQWGTCGAGVSTGIFMSIATGATPLTGA
                     SWGLANQMTARSLSSIGQIGGPRCCKRDSYTAILSAIDFADEQLHIKMERPDSIRCRM
                     SERNAQCIKKACPYHSAV"
     gene            32538..32720
                     /locus_tag="ACZPCR_00910"
     CDS             32538..32720
                     /locus_tag="ACZPCR_00910"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229481.1"
                     /translation="MSRKMSGKMQRELPAQLGTGDDMPHEKRKERAGPLLSGRRRNLR
                     FSSFLNAYGQAFIKGS"
     gene            complement(32704..33885)
                     /gene="gltS"
                     /locus_tag="ACZPCR_00915"
     CDS             complement(32704..33885)
                     /gene="gltS"
                     /locus_tag="ACZPCR_00915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015501 - glutamate:sodium symporter
                     activity [Evidence IEA];
                     GO_process: GO:0015813 - L-glutamate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HIR1229482.1"
                     /translation="MMTLQLDMYQACALGAVVYALGRLMVKKISFLNRYCIPAPVAGG
                     IVFALLHLGLYSAGILEFTFDTTVQTILMTVFFCSVGFTACFRLLKKGGIQVFIFLIL
                     SVLMCVIQDGVGSALAAAFGLDPLLGLCMGSIPLVGGHGTSGSFGPLLEETYGVSGAL
                     TVALAAATYGLVSGSMMGGPIARRRVEKLGLKSTAAQEGNASNDKGGIIDSQKFTNAA
                     VFLAIAIGAGTLIMTGFSKLNITMPGYIGAMLFAALLRNIWDAKGADLPMEEIDTLGG
                     LSLNIYLAMAMMNLKLWQLAALALPMIVILLVQTVIMFLYANFVIFNVMGRDYEAAAM
                     TSAFCGFGMGATPNAMANMKALAERYGAAPRAFFIVPLVGSLFIDFFNSMVLTTFMNL
                     L"
     gene            complement(34017..35558)
                     /locus_tag="ACZPCR_00920"
     CDS             complement(34017..35558)
                     /locus_tag="ACZPCR_00920"
                     /inference="COORDINATES: protein motif:HMM:NF013080.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HIR1229483.1"
                     /translation="MRAKARKISLYLLFFVTLLAYFSAWWAVRTYGSISMEEIVFHLN
                     VPLDGVNTEYIVSYLGTALAPSLAVFFTAMFLYRRCCLFLRTRKTYTCVDVRLGKKRW
                     YVELTDRAFSKSMALLLAFGLVFMAVGTDNLLNIGEYLYNQFHKSSFIEEQYQKPDSS
                     ILTFPEQKRNLVYIYLESMEKTFEDKENGGNLEENVIPELTALADENVTFQLGPDGKQ
                     GILPLTSSWTIAAMVAQTSGLPLKIPVEKNSMSKYGSFLPGAVTLGEVLEDEGYKNML
                     MVGSYASFAGRDQYFKDHGNYKIWDFGTAKREKKVPKDYDIGWWGIEDEKLFEYAKEE
                     LTKLSEGNQPFNFTVLTVDTHNPDGYVCRLCGDEFENQYSNVLRCGSRQAVEFVSWIK
                     EQPWYENTTVVIAGDHATMVKNYAPDDDSYERGVYYCFLNPAAVPADRTHSACTMDLF
                     PTTLAAMGVEIEGDRLGLGTNLFSDRDTILDEFGKEEVISQLNMKSDFYDNELLYGEP
                     AEETD"
     gene            complement(35548..35925)
                     /locus_tag="ACZPCR_00925"
     CDS             complement(35548..35925)
                     /locus_tag="ACZPCR_00925"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229484.1"
                     /translation="MFSFIYLFCPPALALLIYERMEFRRAAFVGEHTRREGSLEWLVN
                     LLLKYLAFTAVVNGAALAIASFFMPISSMASGGHFADNIFSVRYLLTACGTAVVLSVT
                     AKIVSFNLSISVEQKKRVDEHES"
     gene            36273..37445
                     /locus_tag="ACZPCR_00930"
     CDS             36273..37445
                     /locus_tag="ACZPCR_00930"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HIR1229485.1"
                     /translation="MKTEALIYEFDRKVNRFHTNSEKYDGASKFAPNAPKDKIPLWIA
                     DMDFQTAPEIIEAMQKRVEEGIFGYTNIYDSSYYEAVGGWMEKRHGWKVKQEEIVLDS
                     GVVPAVLHALSLMAQPGDGVILHTPSYTPFYNSIRTQGMRTVFSPLLLKNGRYEIDLE
                     DLEKKASDPENKVLIFCSPHNPSGRVWTREELTAVMEICRKHHVSVISDEIHGDLLRA
                     GRTHLSLVGLFPEEKRLIVCTSPSKTFNLAGNHLANIIIPDREIREEWEKRYHYMPNP
                     ISVAATVAAYTRAEGWADALNQYLDGTFQMMEQYIKSHMTGVSFTVPEGTYLAWIDMR
                     NCGLAHKEMVNRFLKNGLLIEGGEQFVADGEGFVRMNIAAPRCVIQEALERMSTLF"
     gene            37504..38418
                     /locus_tag="ACZPCR_00935"
     CDS             37504..38418
                     /locus_tag="ACZPCR_00935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002595855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HIR1229486.1"
                     /translation="MKKKGLVLAAVLMVAAALAGCGSQEKAEETKETAQAAESAGGEE
                     TTAEKETAEEEKAAEGSGRYQSILDAGVLKVGTEGTYKPFTYHDESDTLCGYDVEVAK
                     MIGDKMGVETEYSEITWEGLLTSLDTGTVDLVLNQVGVTPERQEKYDFSDPYLYSYIA
                     LITLEDNEEITDWESAEGKKTSLNVSSNYAGIAEQYGMEITASDTFSKDIELLLAGRT
                     DCVINNTIAFNDYLAQKPDTPIKIVAVQETPDTVAIPIPKGNEDLVEAVNKAIAELSE
                     EGTLTELSEKYLGKDFSREMTLEELTEK"
     gene            38446..39150
                     /locus_tag="ACZPCR_00940"
     CDS             38446..39150
                     /locus_tag="ACZPCR_00940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HIR1229487.1"
                     /translation="MDARAIEILTESFWPILKAGISYTIPLTLIAFVLGTLLAVAVAV
                     IRVSRVPVLNKLCELYVWIIRGTPLLVQLFLVFFGLPKVGIVIEPMPAGIVVFSLSIG
                     AYSSEIFRAAILSIPKGQWEAAMSLGMSYPQQLVRIILPQAVKISVPPLFNSFIALVK
                     DTSLAANITIPEMFLTTQRITARNYEPLLMYIEVGFIYLIFCTVLNYLQKKVEDRLML
                     TPHEKKKIKEITDSQG"
     gene            39160..39891
                     /locus_tag="ACZPCR_00945"
     CDS             39160..39891
                     /locus_tag="ACZPCR_00945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002595854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HIR1229488.1"
                     /translation="MLEIRHLNKYFGDNHVLKDINLEIESKKTTAIIGSSGSGKSTLL
                     RCMNLLETPDSGEISLDGNTLRFPGKLSRKEKAAFTKRTGMVFQGFNLFPHMNALENI
                     TEGPVTVLKRDKKEAREEAMALLKKVGLEDKWNSLPSQLSGGQQQRVAIARALAMKPE
                     ILLFDEPTSALDPELGAGILSLIRDLSQEDYTILVVTHNMSFAREVSEQVVFVEKGTI
                     LAKGSYEELTSMNNERITQFLSYLD"
     gene            39916..40833
                     /locus_tag="ACZPCR_00950"
     CDS             39916..40833
                     /locus_tag="ACZPCR_00950"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HIR1229489.1"
                     /translation="MEQTEKILVLGSLIMDLSVRCRQAPREGETVYTDDDYQANPGGK
                     GGNQAVAAARAGAEVVLLGRIADDDYGRALKESFHRDRIDTSRLITDSSAKTGTAFVW
                     VEENGGNRCLCSLGVNGRNRPEDFIQYESLFQESQIVLTTLEYSKEVLDQVTKMAKQS
                     GCLLIVDPSANDYSKLTPEIAERIDILKPNEVETEMLTGIAVLSPEDAAKAVKRLKEM
                     GIKTPIVSMGSQGVVYDYQGQIIHEPGIEIQAVDTTAAGDTFIGSLAARLSLGKEFPE
                     AVRYANRAASLCVQKKGAQSSIPFMEDVL"
     gene            40972..41445
                     /locus_tag="ACZPCR_00955"
     CDS             40972..41445
                     /locus_tag="ACZPCR_00955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007038310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HIR1229490.1"
                     /translation="MKELKETYELMREYDGLPHDYGNVVLYQSEAHLIQCIGQHTGIT
                     VTEASKILKKTKSACSQMVKKLVGKNWVRQERNKQNNREYKLYLTEEGLVIYDHHENF
                     DRLSYEHNSQELFDFTDEELKKYIQIQQKMNELIKLDVERSYNYFTTTPQELMEK"
     gene            41447..42274
                     /locus_tag="ACZPCR_00960"
     CDS             41447..42274
                     /locus_tag="ACZPCR_00960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002595852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BtpA/SgcQ family protein"
                     /protein_id="HIR1229491.1"
                     /translation="MKRELKNVFATEKPIIGMVHLRPLPGSPGYDPVSMGMDKILENA
                     VEEAKKLEAAGVDGVQVENMWDIPYLRPEDMGYETAAALAVGVYEVRKQVSIPVGAEC
                     HMNGADCAMACAAAAGADWIRVFEWCNSFISQSGFIDAMGAKVARMRKNLGADHILAL
                     CDVNVKHGSHFIIHDRSVEEQAMDVEAQDGDAVIVTGFDTGTPPTVENILKCKESVSL
                     PILIGSGLNSNNVHKLLAAADGAIIGSWFKEDNNWKNPVSFKRAKEFMDRVKALRRQ"
     gene            42354..43667
                     /locus_tag="ACZPCR_00965"
     CDS             42354..43667
                     /locus_tag="ACZPCR_00965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007885709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HIR1229492.1"
                     /translation="MKYTGIELLWLFLLYSFLGWTLETAAGTIRQKRFVNRGFTTGPF
                     CMVYGVAAVVMTAALQELRGSFLFLFLGCMVVGTAVEWFAGKLLERLNQKKWWDYSEK
                     RWNFDGYICAQYSLLWGILGTVTVRWGDGLLVGLCRLLPSFVSSLLTLGAAGMLFLDM
                     AASAATVWHVKRRVKQKDAEKLQQLNSRLASATARLGSRIEARVARRMEKAYPLILEV
                     SEQIARQKVFAGGCGFYKLFWLFLIGAFLGDIVETIFCRLTAGVWMSRSSLVWGPFSI
                     VWGLAIAAATALLYKDREKPDRHLFVIGTVLGGAYEYICSVFTELVFGKVFWDYSKIP
                     FNLGGRINLLYCFFWGIAAVIWIKNLYPLFSGWIEKIPVLWGYAITWMLVAFMAVNIA
                     VSSMALVRYDRRAEGRPPRNAVEQLIDERFNDTRMEKIYPNALSR"
     gene            43774..44553
                     /locus_tag="ACZPCR_00970"
     CDS             43774..44553
                     /locus_tag="ACZPCR_00970"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008397330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1229493.1"
                     /translation="MNSKLEVQGLSYSYHSMDGETKALSNISFQVEEGEFLAVVGPSG
                     CGKSTLLSILCGLLVPEEGSVLIDGEPVKGGSPKIGYMLQRDHLFEWRDVFSNACLGL
                     EIRGQMDREHREKAERLFKTYGLLPFKNKKPSELSGGMRQRAALIRTLALDPDILLLD
                     EPFSALDYQTRLAVCDDISSIIRENRKTAVLVTHDLAEAVSAADRVLILTRRPGRIKT
                     VLPITFAEPSLSPLERRSAPEFSGYFNQVWKTLENREVSHE"
     gene            44546..45346
                     /locus_tag="ACZPCR_00975"
     CDS             44546..45346
                     /locus_tag="ACZPCR_00975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003508372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1229494.1"
                     /translation="MNNRETLAQRTFVAGQRRYRRRIAAGRILLFFAFLAVWEAGADT
                     GLLDDFIFSSPSRALRCFFVMASDGSVFPHLGATLLETVVSFFLVTALGLGGALALWE
                     SRTASDLLEPYLVMLNSLPKSALAPLLIVWLGSNMRTIVTAAVSVAVFGSVLTLYQGF
                     LSMDPDQEKLIYSLGGTRRDVLRKALLPGSIPLIVSNMKVNAGLCLVGVMIGEFLAAD
                     KGLGYLIIYGSQVFKMDLVIMSIVILCLMAALLYQGIAFLEKKVSRRL"
     gene            45428..46297
                     /locus_tag="ACZPCR_00980"
     CDS             45428..46297
                     /locus_tag="ACZPCR_00980"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015544587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HIR1229495.1"
                     /translation="MIQTDTGNKTTLRNYEIALIQMDTQNDKGENMKKACRFIDEAAG
                     HGAKLICFPEVMNLIGRNIGEGGGKEEIPGYTSDILCRKAREHKVWIHGGSITEQVPG
                     QKKSRNLSLLINPDGEIAAQYRKLHMFDITLADGTPFRESDRVEGGNEITTVSTELGT
                     FGMSICYDIRFPELYRLMALQGAQVMFVPASFTMPTGKDHWEPLLRARAIENGCYIVA
                     AGQIGTKPAYAAYGNSMVVDPWGTIIARARDTECITYAQIDLDYLDQIREQLPSLENR
                     RTDVYEVISKKEK"
     gene            46563..47381
                     /locus_tag="ACZPCR_00985"
     CDS             46563..47381
                     /locus_tag="ACZPCR_00985"
                     /inference="COORDINATES: protein motif:HMM:NF014635.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF169 domain-containing protein"
                     /protein_id="HIR1229496.1"
                     /translation="MEKQLIKRFSKALGLSRQVVGIKFIFLKEEYEDLDVPEPKAGGC
                     FCALTARAMEGKIMKGKADTFGCQGGPEMLGMKKVSNYVWSGKQFSTLRLYEDAAIAR
                     QVQQDLCFVDQRIYGVMTGPLEEMEDADVVMLLCNGWQMMRLIQGYTWHHGMAKNIGM
                     IGNQGICADLVARPYMKNDLNVSMLCLGARTNTSAEDGEIGAGMPVHLFRDVAEGVLK
                     TVNPAMSDKEKQALSERLETPDELGFEIEFGKVYMSYAKEKKYPEELYKQSGND"
     gene            47494..49203
                     /locus_tag="ACZPCR_00990"
     CDS             47494..49203
                     /locus_tag="ACZPCR_00990"
                     /inference="COORDINATES: protein motif:HMM:NF012706.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIR1229497.1"
                     /translation="MKKKFARILAAGLAACMMTGCSIGQKTDTPAETSKGASQAETTG
                     GQETEGEKKDTVVYGTPTAPVGTFFPILSYMGSDIALEKLIYASLFTFDSEGSLKPYL
                     AESYTVSEDQKTIDFKIRQGVKWQDGEDFTMDDLIFTIESAAKSVEDFEKVAYVKGAA
                     EYKDGQADSISGVSVPEENVLRLELTEPYAPFMADFGTYGIIPKHVWSEIPQEEWEKQ
                     TELLNQPVGCGPYKVTKFEPGQYVSLEAYEDFFEGAPKIDNFILKVVNQDAISAELVS
                     GNIDIVDVKEMRSSEIEELEAQGFAKYSIPDHMYQYISFNLRRPEFQDKNLRQAMLYA
                     IDRALILDTIVEGRGKLLDSPFLPGSWASPAEGELNKYAYNPEKAKELLEASGWTDAD
                     GDGVRENGDGEKLQFTIRCSNDSKTRENAVLYAKECLAEVGIDVEVSIEEDSVIAEDC
                     IYNHNFEMYALNCYFFEDPNPYGWWHSDSAFDEPGVGSFNFGAYKNDLVDENIEKGMK
                     TTNQEERKEYYLNVAKQINEDVPMIFLYAQDREIMCNPKLENFDPYTFNIFCDIWEWD
                     FAQ"
     gene            49222..50193
                     /locus_tag="ACZPCR_00995"
     CDS             49222..50193
                     /locus_tag="ACZPCR_00995"
                     /inference="COORDINATES: protein motif:HMM:NF012738.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1229498.1"
                     /translation="MARFISRRLAAALIMLLGVTAVIFCIIRLQPGNPFLNMIQHDTD
                     PTFLETKLQEIGYYDPLPVQYGKWLLRTLQFDLGYSIQHRTPVAALIADRFGNTLLLA
                     MSSFVLSTVISIGIGVFSAMYPNSLWDRALTVLSFIGVSIPVFFFGLLLIKVFGYDLA
                     VLPFSGIETMGKNYQGIDRALDIGRHMILPVTASALTQTATLLRYTRSSILSTVSEDY
                     MKTAQAKGLTKKQAILRHGMRNARVSIITVLCNRLPDLLSGALIVETIFVWPGIGQLN
                     YQAILVRDYPLIMGIALLLAVIVIGCNLLADVLCMILDPRVRNSVGV"
     gene            50238..51110
                     /gene="opp4C"
                     /locus_tag="ACZPCR_01000"
     CDS             50238..51110
                     /gene="opp4C"
                     /locus_tag="ACZPCR_01000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013656326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HIR1229499.1"
                     /translation="MKKREEEKILTAGQIARRRFFRNRLATAGLIIVVSFVFLSLFAP
                     LFTDYTVSQTDLRNLRSGPSAAHLLGTDDLGRDIFARLLYGGRVSIAVGVASMLLQMA
                     IGVTLGAAAGYFGGVTDKVIMRMVDIIMCFPFFVIAVALAAVIGGSIWNLILIIGMLM
                     WPGIARIVRTEVLTIRDNEYIMAAKALGLSPVQIIVKEVLPNVFSSILVASTLAVANG
                     ILMESTLSFLGLGVRPPAPSWGNMLVAAQNMAVLKNQWWMWIPAGAAVVLMVLAINFL
                     GDGLRDALDTRNQQ"
     gene            51124..52101
                     /locus_tag="ACZPCR_01005"
     CDS             51124..52101
                     /locus_tag="ACZPCR_01005"
                     /inference="COORDINATES: protein motif:HMM:NF012235.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1229500.1"
                     /translation="MEEILKVNHLNVVFDDISGPLTAVYDVNFGLRRGEILGIIGESG
                     SGKSVTARSVIQLAQVGKRGSISGEILFQGTDLLKLKEKEMCRIRGSRITMVFQEPMT
                     ALNPAMTVEEQLSEVLKLHSPGEREKHRERILETLRQVQLPEPEILMKKYPFELSGGL
                     RQRVVIAMAVIGKPDIIIADEPTTALDVTTQAEILSVLKKIAGEMGSAVILITHDLGV
                     VAEIADRVLVMYRGMGVEECRTASLFDEPLHPYSQGLLSSRPSNFNGRYSAIPGTVKQ
                     NYGVFKGCPYSDRCPYALETCREKIPPSLSFGGEHRAACWKLCKEGSSE"
     gene            52094..53077
                     /locus_tag="ACZPCR_01010"
     CDS             52094..53077
                     /locus_tag="ACZPCR_01010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1229501.1"
                     /translation="MSEIILKAEHLKKHYEERQGLFSRKKRINAALDDVSLEIRKGSI
                     MGLAGESGSGKSTAGKTMLNLIKPSGGRVIFEGKQIFDADKGEYLDSGSMTALRQKMQ
                     IIFQDPSSSLNPKKNVEQIISAGIIKHRLCSGSQVRERCIEIMEKCGLDKRQMMRYPH
                     EFSGGQKQRIGIARALAVEPSFIVCDEPTAALDMSIQSQILNLMLDLKEQYGLTYLFI
                     SHNLGVVEHFCDELAVMYRGKIVEQGKTADLFSSPVHPYTQLLLSSVPVSHPDEPRRH
                     TGGQPQDESILKHGCRFAPRCPYREKRCTEQEPLLLPCGEGHTAACFHAVK"
     gene            53285..54553
                     /locus_tag="ACZPCR_01015"
     CDS             53285..54553
                     /locus_tag="ACZPCR_01015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005331449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1229502.1"
                     /translation="MILGNLLQQLYSTADSIIVGNFVGSNALAAVGSSTALIGLLIAF
                     SQGVSVGAGVVAAQYLGAKNRRDVQGSIHTAFALAAVLGIILTAGGIICSRPLLVWMN
                     TPEEVLEDSVIYLQIYFGGLIFNVLYNMAAGILNAAGNSKRSLIYLAYASVTNIGLDL
                     LLIGVFKMGVAGAAIATDASQLVSCILSMWYLTHVDADYRISLKKIGIDKRMAVRIAK
                     IGLPTGIQNMVISFSNVLVQSSVNSFGAAAMAGFGAYMKIDGFNILPVLSFSMAVTTF
                     TGQNYGAGKIERVKKGMWITVLMGCVYTIVTGTLLLTFGDPLMRLFTDSREVIEHGKL
                     AMKYFCPFYFLLSIMHSLAGTIRGAGKSIPPMLILLFAMCLFRIFWIKAILPAFGTLD
                     GVYMLYPVSWAVGMVLMVLYTWKGKWLEEQ"
     gene            54841..55308
                     /locus_tag="ACZPCR_01020"
     CDS             54841..55308
                     /locus_tag="ACZPCR_01020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HIR1229503.1"
                     /translation="MARREEYESKVEAWLLPLLEKNQFELVDVEYVREAGIWYLRAYI
                     DKEGGITVDDCEVVSRELGDWLDQKDFIEDSYILEVSSPGLGRPLKKEKDFARSLGKD
                     VEVRLYRPINKQKEFTGTLKAYDADTVTLSMEDGNDLALAKSDIALIRLAFDF"
     gene            55333..56514
                     /gene="nusA"
                     /locus_tag="ACZPCR_01025"
     CDS             55333..56514
                     /gene="nusA"
                     /locus_tag="ACZPCR_01025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HIR1229504.1"
                     /translation="MSKELFEALNVLEKENNISKEVLFEAIENSLLTACKNHFGRADN
                     IKVYIDREKCDFAVYAEKEVVEVVEDPLTQVSLAEAKLLDPRHVYGDVIRVNINSKEF
                     GRIATQNAKNVILQKIREEERTALFDQWYCKEKDVVTGIVQRYVGHDVYIDLGKIDAV
                     LKESEQVKGEEFKPTEHIKLYILEVKNTKKGPRITVSRTHPDLVKRLFESEVAEVKDG
                     TVEIKAIAREAGSRTKLAVASNDPNVDPVGACVGLNGARVNSVVSELNGEKIDIINWD
                     ENPALLIENALSPAKVIFVAADEEAREAQVIVPDYQLSLAIGKEGQNARLAARLTGFK
                     IDIKSETQARESGLFDEMEIGYEQGFEEGLPEGVEADDFSDYEELSSDFSAESETEEE
                     N"
     gene            56572..56847
                     /gene="rnpM"
                     /locus_tag="ACZPCR_01030"
                     /gene_synonym="ylxR"
     CDS             56572..56847
                     /gene="rnpM"
                     /locus_tag="ACZPCR_01030"
                     /gene_synonym="ylxR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003508382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase P modulator RnpM"
                     /protein_id="HIR1229505.1"
                     /translation="MGMKKIPLRQCIGCGEMKSKKEMIRVLKTTEDEIVIDATGRKNG
                     RGAYICPSMECFKKAVKSKGLERSLKMAIPKEVYEALEKEMGQIGQQ"
     gene            56834..57166
                     /locus_tag="ACZPCR_01035"
     CDS             56834..57166
                     /locus_tag="ACZPCR_01035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L7Ae/L30e/S12e/Gadd45 family ribosomal protein"
                     /protein_id="HIR1229506.1"
                     /translation="MDSSKKALNLLGIATKAGKTASGEFMTEKAVKEGRAFLVLVSEE
                     ASVNTKKMFTNMCTYYKVPLYFFGTKEELGHSMGREMRASAAVLDSGLAKALVKQLNQ
                     NGGGVNES"
     gene            57156..60077
                     /gene="infB"
                     /locus_tag="ACZPCR_01040"
     CDS             57156..60077
                     /gene="infB"
                     /locus_tag="ACZPCR_01040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002590164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HIR1229507.1"
                     /translation="MRVNELSRELGKTNKEVLDLLKKQGYDVKSHSSNINSDQIDAVK
                     RCFSERPAQREQVQKERTGKAEAARVEEIKREPVRTEADGNGTAEPPKKRITAVYRPQ
                     NSTAKGTGSKAGGQRTGRQGQGASSQGNRDGQGNRDGQNRGYGRDGQGNRDGQNRGYG
                     RDGQGNRDGQNRGYGRDGQGNRDGQNRGYGRDGQGNRDGQNRGYGRDGQGSRDGQNRG
                     YGRDGQGNRDGQNRGYGRDGQGNRDGQNRSYGRDGQGNRDGQNRSYGRDGQGNRDGQN
                     RGYGRDGQGNRDGQNRGYGRDGQGSRDGQNRGYGNRDGQRGRSGSSKPSFDGPVVQKP
                     QNTKQNKNNYKNDYKNDKYSRPDREEEMRSKSGRGGKPGKGAFIMPQKKEEPKAEQVK
                     TIVLPETITIKELAEKMKMQPSVIVKKLFLQGTVVTINQEVDYDKAEEIAMEFDILCE
                     KEEKIDVIEELLREDEEDEKDMTERPPVVCVMGHVDHGKTSLLDAIRQTHVTAKEAGG
                     ITQHIGAYVVEKNGQKITFLDTPGHEAFTAMRMRGAKSTDIAILVVAADDGVMPQTVE
                     AINHAKAAGVEIIVAVNKIDKPSANVEKVKQELIEYELVAEDWGGSTVFVPVSAHTGE
                     GIEELLEMILLTSEVKELKANPNRRARGLIIEAELDKGKGPVATVLVQKGTLHVGDPV
                     ACGSCYGKVRAMMDDKGRRVKEAGPSTPVEILGLNDVPNAGEVFVATENEKEARSFAE
                     TFISEGKNKLIEDTKAKLSLDDLFSQIKAGNVKELPLIIKADVQGSVEAVKQSLTKLS
                     NEEVMVKVIHGGVGAINESDVNLAAASNAIIIGFNVRPDATAKSISEREKVDVRLYRV
                     IYQAIEDVEAAMKGMLDPIFEEQVIGHAVVRQTFKASGVGTIAGSYVLDGKFQRGCKA
                     RITRDGEQIFDGNLASLKRFKDDVKEVASGYECGLVFEKFNDLQEDDMIEAYAMVEVP
                     R"
     gene            60120..60518
                     /gene="rbfA"
                     /locus_tag="ACZPCR_01045"
     CDS             60120..60518
                     /gene="rbfA"
                     /locus_tag="ACZPCR_01045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003508393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HIR1229508.1"
                     /translation="MRKNSIKNTRINSEVQRELSSIISREIKDPRIHPMTTVVSVEVT
                     PDLKYCKAYISVLGSEEAGKDTIKGLKSAEGFVRRQLANRINLRNTPEIAFVLDQSIE
                     YGVHMTHLINEVTKDLDTDEDTEQETEEQL"
     gene            60588..61574
                     /locus_tag="ACZPCR_01050"
     CDS             60588..61574
                     /locus_tag="ACZPCR_01050"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HIR1229509.1"
                     /translation="MNQLLESRLNLAKTAVILGHVHPDGDCVGSTLGLYNYLTANYPE
                     LKADVYLDHPDRKFSYLKQFDRIHCEYEEGKRYDLCITCDSSDAERLGAFRPYFDTAK
                     HTFCVDHHVTNRGFAEENCVEPDASSASEVVCTLLDMEKIDLAAAECFYTGIVHDTGV
                     FKFSCTSGRTMEIAGKLMDKGIDTTEIIDGSFYRKTYVQNQILGRALLESVLFMDGRC
                     IFSSVTKKEMEFYGVTNKDLDGIIDQLRLTAGVEVAIFMYETGSSEFKVSMRSCRYVD
                     VSQIAAYFGGGGHVRAAGCTMSGTLHDVLNNLAPHIERQILAWEAEHKCFTE"
     gene            61559..62494
                     /gene="truB"
                     /locus_tag="ACZPCR_01055"
     CDS             61559..62494
                     /gene="truB"
                     /locus_tag="ACZPCR_01055"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002600703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HIR1229510.1"
                     /translation="MFHGVINIYKEPGYTSHDVVAKLRGILKQKKIGHTGTLDPAAEG
                     VLPVCLGKGTKLCDMLTDKTKTYQAVMLLGVSTDTQDTTGTVLSERSTEGVDEAAAAE
                     AAESFVGLYHQIPPMYSALKVNGKKLYELAREGKEVERQARPVEIFSLSIDKMELPRV
                     TMTVHCSKGTYIRTLCHDIGEKLGCGACMEHLLRTQVDRFLVKDSLTLSQMEELVKEG
                     TVQERIVPVDQMFSHFPAFYSEDETLDRLLSNGNFFLKSQARGRWEPDAGQDTPEQDG
                     SMCRVYDGSGRFIGVYEYRASEKKWKPRKIFLGGD"
     gene            62497..63423
                     /locus_tag="ACZPCR_01060"
     CDS             62497..63423
                     /locus_tag="ACZPCR_01060"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HIR1229511.1"
                     /translation="MEYIRGTREFQIEEPTAVTLGKFDGLHRGHKKLLEELFRFREKG
                     CKTAVFTFETAPGTLIRKKLQTMITTNEERYENLRDAGVDYLVEYPFNEQVASMSPEE
                     FVVHVLKGQMNAEAIVAGTDFHFGRNRSGDVAFLKANAEKFRYDLTVVEKAMDGEREI
                     SSTYIREELAAGRIEKANELLGYTYSIQGRVVHGKHLGTGMGFPTVNLLPPSQKHLPA
                     FGVYLSEVEIDGKLYPGITNIGRKPTIKGEHPAGVETHIYDWTRDIYGKDVKVRLLTF
                     MRPEKKFDSVEELKAQVLHDKEEGRIWHQNRL"
     gene            complement(63613..64791)
                     /locus_tag="ACZPCR_01065"
     CDS             complement(63613..64791)
                     /locus_tag="ACZPCR_01065"
                     /inference="COORDINATES: protein motif:HMM:NF033550.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HIR1229512.1"
                     /translation="MPTSNFTAKLLELEEIIISDFTSSNTEIHIHFSLPRKACTCPHC
                     LGLTDKVHDYRISIIKDLPIMGKHTFLHYRKRRYHCPLCGKHFYEPFSLAAKHCRTTT
                     RLAFYAIHLLSERQCVRSVSRLLDLSDSYIFRRLKAVQFPKPDRLPTVLSIDEFKGNA
                     GGEKFQAILTCPDKHSLFDILPSRSQVSLQQYFQGFKNKKEVRFIVMDMNKVYRELAK
                     DYFPQATIVIDKFHVVRYVTWALENVRKRIQKQLHPDKRKYFKRSRKLLLTHKSKLKE
                     ESMDALAVMLSQSEDLAIAYHLKELFYDFMKSMSRTEATKKLKFFLLAAQASQLKEFH
                     ACLTMLANWSKYILNAFDCPYTNGFTEGTNNAIKVIKRNAFGYRNFKNFRNRIFLALT
                     "
     gene            complement(64942..65376)
                     /locus_tag="ACZPCR_01070"
     CDS             complement(64942..65376)
                     /locus_tag="ACZPCR_01070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009249248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HIR1229513.1"
                     /translation="MNRLQIVIIDGQGGRMGKGIVEQLKKRFPDLPLTAVGTNSIATA
                     AMMKAGADWGATGENPVVVNSRSADVIIGPVGIVIADALLGEVTETMAAAVGKSPAHK
                     LLIPVSHRCSHTVVGCRELSLSEYIRIACDEVERMLAEESHL"
     assembly_gap    65598..65607
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            65662..68877
                     /gene="carB"
                     /locus_tag="ACZPCR_01075"
     CDS             65662..68877
                     /gene="carB"
                     /locus_tag="ACZPCR_01075"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HIR1229514.1"
                     /translation="MRRNDIHKVMIIGSGPIIIGQACEFDYSGTQACKALKKLGYEIV
                     LVNSNPATIMTDPETADVTYIEPLNVDRLEQIIAKERPDALLPNLGGQSGLNLCSELA
                     AAGVLDKYNVQVIGVQVDAIERGEDREEFKETMESLGIEMARSEVAYSVDQALEIADK
                     LGYPVVLRPAYTMGGEGGGLVYNVEELKTVCARGLQASMVGQVLVEESILGWEELELE
                     VVRDSKNNMITVCFIENIDPVGVHTGDSFCSAPMLTISEEVQKRLQEKSYKIVEAIQV
                     IGGTNVQWAHDPKTDRDIVIEINPRTSRSSALASKATGFPIALVSAMLATGMTLDEIP
                     CGKYGTLDKYVPSGDYIVIKFARWAFEKFKGSQDKLGTQMKAVGEVMSIGKTYKEALQ
                     KAIRSLERGRYGLGHAGFEGKSKKELLSMLHTVSSERQFIMYEALRKGATVEELHNLT
                     QIKSYFIAQMKELVEEEEALLKYKGQVPPVEVLRQAKLDGFADKYLSELLEISEEAVR
                     DARTEAGIEEGWEGVHVSSTEDSAYYYSSYHIKDESPCTDNKKIMILGGGPNRIGQGI
                     EFDYCCVHAAVALKELGFETIIVNCNPETVSTDYDTSDKLYFEPLTLEDVLSIYHKEK
                     PLGVIAQFGGQTPLNLAADLKKYGVNILGTTPETIDMAEDRDLFREMMDKLNIPMPES
                     GMAVNVDEALAIANKIGYPVMVRPSYVLGGRGMEVVHDDNALSFYMQQAVGVTPDRPI
                     LIDRFLHHATECEADAISDGENVFVPAVMEHIELAGIHSGDSACILPSRNLTLDQVET
                     IKDYTSRIAKEMHVVGLMNMQYAIEDGEVYVLEANPRASRTVPLVSKVCNIKMVKLAT
                     DIMTSYLTGRPSPVPELKEKKIPHYGVKMPVFPFKMFPEVDPVLGPEMRSTGEVLGMS
                     ANVGEAIYKAQEATQTRLPAKGTVLLSVNDKDKAELIEVANGFHECGFELMGTGRTCD
                     IMVAAGLPAKKVAKIDEGRPNILDKITNREVDIIINTPLDRKGMGDDSYIRKAAVKGK
                     IPYFTNMAAAKATVQALRTIKKNGHLGVKSLQEFHSEIREQ"
     gene            69086..69577
                     /locus_tag="ACZPCR_01080"
     CDS             69086..69577
                     /locus_tag="ACZPCR_01080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002575247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1229515.1"
                     /translation="MKETLYETLISCITENQNRFYRVAYSYVKNEEDALDAVQNTVCK
                     ALESYRNLKNAEAVRTWFYRILINESIDIMRQRKKFLLSEDYPGAEKIYEERGYEPEE
                     EIARELEDLEEGTQQIIKLRFFEELSLKEISEITGIDLSTVKTKLYRGLKSLKESIQE
                     VDE"
     gene            69574..69768
                     /locus_tag="ACZPCR_01085"
     CDS             69574..69768
                     /locus_tag="ACZPCR_01085"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229516.1"
                     /translation="MSRLEDMKKDYENVKIPDELNIRIEKEIAKSRAREKMIQLSHRK
                     RWFRNTAAAAAAVCVVLPQR"
     gene            69708..70424
                     /locus_tag="ACZPCR_01090"
     CDS             69708..70424
                     /locus_tag="ACZPCR_01090"
                     /inference="COORDINATES: protein motif:HMM:NF023166.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsiV family protein"
                     /protein_id="HIR1229517.1"
                     /translation="MVQEHGSSRCGRMRGFTTALNTSTAFAEEAAQLPVIGTLARVLT
                     FRNYEAEKNGIGIAVEVPTIDMIQTETGIQVDEVNQQIYDLCRQYADEYRKAFLDTGG
                     TEEEWEAHKIQINVGYEIKSQTDQYLSFIVRGRESWTTAYSESRYYNIDVNTGKRVTL
                     ADFFGKDYVEAVNTDIREQIAQRKEAGEVFWTEEEGGFSGITEDAKFYVNEAGNPVIA
                     FERYEIAPGSSGEIEFEIQP"
     gene            70460..70936
                     /locus_tag="ACZPCR_01095"
     CDS             70460..70936
                     /locus_tag="ACZPCR_01095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229518.1"
                     /translation="MKKTNLTLAALLVSIAAASFAVTGCGKNEKAEETTASEMLETSS
                     GYEDNFAVDSRAAAEFADKIKEAVAAEDLEALADLTAFPVYVDIENANDVKTREDFLA
                     LGAEAIFTEELKKSAANADTENMQPSMAGFSVSDGGSANINFGVRDGVLAVNGINY"
     gene            71139..71771
                     /gene="yedF"
                     /locus_tag="ACZPCR_01100"
     CDS             71139..71771
                     /gene="yedF"
                     /locus_tag="ACZPCR_01100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008977018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HIR1229519.1"
                     /translation="MKQLDMRGKACPMPVIETKKLLEELNRAEAVTVLVDNEIAVQNL
                     TKLAGHEGMDVSSDKHSDKEFAVVFTPAEGGSAEAQSTEGQETAQEDLIVENHIAKGR
                     VVVIASDKMGEPEEELGKILIKGFIYALSRQDALPETILFYNGGAKLTAEGSESVEDL
                     KYMAEQGVEILTCGTCLKHLGLEDKLQVGAVSNMYEIAEKMTEAGQLIRP"
     gene            72004..72387
                     /locus_tag="ACZPCR_01105"
     CDS             72004..72387
                     /locus_tag="ACZPCR_01105"
                     /inference="COORDINATES: protein motif:HMM:NF038093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HIR1229520.1"
                     /translation="MYLLVTNNGLCFEKYQNRVKVDYLEDGSYLDVLVKVRDYVQKGY
                     RIETHPMAGSIKPNQTPFRTVLVSDEKMDGNEMIENELMIEDAVLMTRKFLSDHPVRD
                     WEKSIVRDFGQVDLELISGAIDRIV"
     gene            72745..74025
                     /locus_tag="ACZPCR_01110"
     CDS             72745..74025
                     /locus_tag="ACZPCR_01110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002565760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HIR1229521.1"
                     /translation="MKLELGIIPVKDIQFGPESKVENGVIYVNADELRALLLEDENLK
                     SVEFDIARPGESVRIMPVKDVIEPRVKVSGEGAMFPGMISKVATVGSGRTNVLRGSAV
                     VTTGKIVGFQEGIIDMCGTGAEYTPFSKLNNLVVICEPVDDIQKHAHEKAVRMAGLKA
                     ADYIGKLAKEIEAEEIETYETETVKEGLEKYPNLPRVAYVLMLQSQGLMHDTYVYGVD
                     MKQSLPTIINPTETMDGAILSGNCVSACDKNTSYHHLNNPVIKSLFDQHGKTLNFVGV
                     IITNENVYLADKMRSSDWTSKLCKWLDVDGAIVSQEGFGNPDTDLIMNCKKIEGQGVK
                     TVIITDEYAGRDGASQSLADADAAADAVVTGGNANMVITLEPKDKVIGYPEVADIIAG
                     GFDGSLQADGSIVAELQVITGATNEMGFNKLSAR"
     gene            74035..75348
                     /gene="grdB"
                     /locus_tag="ACZPCR_01115"
     CDS             74035..75348
                     /gene="grdB"
                     /locus_tag="ACZPCR_01115"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006316653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030700 - glycine reductase complex
                     [Evidence IEA];
                     GO_function: GO:0030699 - glycine reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050485 - oxidoreductase activity, acting
                     on X-H and Y-H to form an X-Y bond, with a disulfide as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:75082..75084,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HIR1229522.1"
                     /translation="MGKLKFVHYINQFFANIGGEEKADYAPEVRDGVVGPGLAFNQAF
                     GEEAEIIATVICGDSYFNENVDSATETVLNMIKEKAPDGVICGPAFNAGRYGVACGTV
                     AAAVKEQLGLPVVTGMYKENPGADMYKNKVYMCPTKNSAAGMRDAVKKMAPLALKLVK
                     GEKIGSSKEDNYMPNGKRVNFFEDKRGAERAVEMLVKKLNGKEYETEYPMPSFDRVAP
                     GAAIVDMAHAKIALVTSGGIVPKGNPDHIESSSASKYGQYDIEGVMDLTEETYETAHG
                     GYDPVYANQDADRVLPVDIVEEFIKEGKIGSLHKYFYTTVGNGTAVASASKYAKEIGQ
                     KLVDDHVDAVILTSTUGTCTRCGATMVKGIEAYGIPVVHIATVVPISLTVGANRIVPA
                     IAIPHPLGNPALSLEEEKDIRRKIVGKALEALQTPVDDQTVFEWK"
     gene            75429..76370
                     /gene="trxB"
                     /locus_tag="ACZPCR_01120"
     CDS             75429..76370
                     /gene="trxB"
                     /locus_tag="ACZPCR_01120"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HIR1229523.1"
                     /translation="MGKIYDVIILGAGPGGLAAGLYSGRYRLDTLVIEKAKDGGQIAI
                     TDEIENYPGQKVEGESGPSLIARMTQQVEKFGAERVTDTINKVELEGPVKKLYGTKGE
                     YECKCLIIATGAYPRPIGCKREGEFVGKGVSFCATCDANFFEDFEVFVVGGGDSAVEE
                     AMYLTKFARKVTIIHRRDELRAAKSIQEKAFKNPKLHFMWDTVVDGLEGDEILSAMTV
                     KNVKTGEITRVEADPEDGMFGVFGFIGYIPRTDLFEGVIDMENGYIKTDDNMHTNIPG
                     VFAAGDVRVKSLRQVVTAAADGAIAAQQAEKYIAEME"
     gene            76517..76834
                     /gene="trxA"
                     /locus_tag="ACZPCR_01125"
     CDS             76517..76834
                     /gene="trxA"
                     /locus_tag="ACZPCR_01125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxA"
                     /protein_id="HIR1229524.1"
                     /translation="MVDLTKENFEEEVLKAEGTVLVDFYGDGCVPCQALMPHIHAMED
                     VYGKDIKFTSLNTTKARRLAIGQKVLGLPVIAIYKGGEKVAECVKDDATPENVEAMIK
                     ANL"
     gene            76997..77470
                     /gene="grdA"
                     /locus_tag="ACZPCR_01130"
     CDS             76997..77470
                     /gene="grdA"
                     /locus_tag="ACZPCR_01130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_083687502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030700 - glycine reductase complex
                     [Evidence IEA];
                     GO_function: GO:0030699 - glycine reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050485 - oxidoreductase activity, acting
                     on X-H and Y-H to form an X-Y bond, with a disulfide as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:77126..77128,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HIR1229525.1"
                     /translation="MAILNGKKTIIIGDRDGIPGPAIEECVKTAGAEVIYSSTECFVU
                     TSAGAMDLENQKRVKDFAEQYGAENVVVILGAAEGEAAGLAAETVTAGDPTFAGPLAG
                     VQLGLTVYHICEDEIKAEVDPGVYDDQISMMEMVMDVDDIHNEMSSIRDEFCKYL"
     gene            77582..79132
                     /gene="grdC"
                     /locus_tag="ACZPCR_01135"
     CDS             77582..79132
                     /gene="grdC"
                     /locus_tag="ACZPCR_01135"
                     /EC_number="1.21.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002565766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     component C subunit beta"
                     /protein_id="HIR1229526.1"
                     /translation="MGGYPVLKGASYVLAVVPDMVLENGTTQTTEKIVNPDSEYLKEL
                     PKHLRSFEDAVSYLPNQIYIGNEKPEALRGIEFPFFNTKWENAKRDGKYGQIMPQDEF
                     YGLMQICDVFELVHLEKAFAASVKEKLAALNILTDEQLAVLDGNQSTEDDIKALVEGE
                     HSEPLYDGGKLVGAIKRAHDVDVNLSAHTMLENIVAKASSVLALIELVKKGGVDPNEI
                     DYVIDCCEEACGDMNQRGGGNFAKAAAEVAGFTNATGSDVRGFCAGPAHAIVHAAALV
                     QSGAFKNVVVTAGGCTAKLGMNAKDHVKKGVPVLEDCVAGFSVLISANDGVSPVLRTD
                     IIGRHTIGTGAAPQNVISSLVTAPLEAAGLKILDIDKYSPEMQNPDITKPAGAGDVPE
                     ANYKMIAALGVKKGELQRNEIASFVSEHGMVGWAPTQGHIPSGVPYMGALRDEILAGE
                     TKRAMIIGKGSLFLGRMTNLFDGISFVVEANDGSGADDGQAVDEKQIKSMIGQAMKEF
                     AKGLLEEQ"
     gene            79157..80278
                     /gene="grdD"
                     /locus_tag="ACZPCR_01140"
     CDS             79157..80278
                     /gene="grdD"
                     /locus_tag="ACZPCR_01140"
                     /EC_number="1.21.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     component C subunit alpha"
                     /protein_id="HIR1229527.1"
                     /translation="MSEAKIKKMIAETFLEVADALETGRYGKKAVIGFACEGSEHGQE
                     NIDRAFELAVRKGLTPYMIEGEDIHKKMEELLESGEIDAAVTMHYPFPVGVSTVGKII
                     TPGMGKAMYLATTTGTSDTDRVSAMVKNAIYGIIAAKADGIENPTVGIANIDGARQTE
                     KYLLQLKENGYDIHFADSARADGGIVMRGNDLLGASADVMVMDSLTGNLMTKIFSAYT
                     TGGSYESLGFGYGPGIGPDFDKLVMIVSRASGAPVIAGAMEFATNLINHDWKKIVKDE
                     WKKAEKAGLKSILDEIKKANTKKSDGDDEEVAMPPKEICTEQIPGIEVMDLEDAVKVL
                     WKNGIYAESGMGCTGPIVRMAADKKEKAVELLTAAGYIG"
     gene            80519..80612
                     /locus_tag="ACZPCR_01145"
     tRNA            80519..80612
                     /locus_tag="ACZPCR_01145"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:80554..80556,aa:Sec,seq:tca)
     gene            80654..82066
                     /gene="selA"
                     /locus_tag="ACZPCR_01150"
     CDS             80654..82066
                     /gene="selA"
                     /locus_tag="ACZPCR_01150"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005539697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004125 - L-seryl-tRNA(Sec) selenium
                     transferase activity [Evidence IEA];
                     GO_process: GO:0001514 - selenocysteine incorporation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HIR1229528.1"
                     /translation="MGERQELLRKIPKIDEVLQDERLIFFMEKTPRSVVVEAVRQQIN
                     ELRNGILQGSIEEATGVNEIVEGALKQIKLRKKRSLRRVINATGIVLHTNLGRANLSD
                     TAIEGVCEAAAHYSTLEYDLKKGARGSRHSHVEEIIKQVTGAEAAMVVNNNAAATMLC
                     LSAMARGKEVIVSRGELVEIGGSFRIPEIMEESGAILRDIGTTNKTKVSDYVNAYEEG
                     VTGALLKVHTSNYKIIGFTQETTVSELSELGKQWNLPVIYDLGSGLMNDLSDFGVDEP
                     TVQSALRDGADVVLFSGDKLLGGPQGGIIIGKKEFIDRMKAHPLARAFRVDKMTLSAM
                     EATFFEYLDRTTCRKNIPILRMLTMTADELHKKAEALKALLEKETEGFLFQVEACQDQ
                     VGGGSAPGVMIPGYAVSVRSGSITEAKIERCLRKAELPVIAHVFRDAVYLNVRTIEED
                     EYPLIAKALGGAENCDREEQ"
     gene            82071..83984
                     /gene="selB"
                     /locus_tag="ACZPCR_01155"
     CDS             82071..83984
                     /gene="selB"
                     /locus_tag="ACZPCR_01155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0001514 - selenocysteine incorporation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HIR1229529.1"
                     /translation="MQNVIVGTAGHVDHGKTCLIKALSGIDTDRLKEEKKRGITIELG
                     FANLIDTDGVHIGIIDVPGHEKFVKNMLAGIGGIDLVLLVIALDEGVMPQTVEHFEIL
                     KMLQIRQGIVVLTKSDTVDSDWADMVEEDVRELIKGSFLEQAELIRVSSYTGENIDVL
                     RQKIVTMAKQAGKRREEKELFRLPIDRVFTMEGFGTVVTGTLIEGMCEAGEEVMVYPQ
                     ERLLKIRGVQSHGQKEEKACAGQRTAINLAGIKKEELSRGEVLAYPGSLVNSTMVDAT
                     LRLFDSTQRKLKNGDRVHLSYGSAQAIGKVILLDCDVVEAGQEALVQLRFDDPICVKR
                     NDKFIIRFYSPVETFGGGTVLNPAADKHKRGQEDVIESLKLKKTGTDMEILEQMVNEE
                     SRRFPEAEDLAAWMDLTVSEAEQMLDTLRNKKKILHLNDGSFVGKAYWEKVSELANQV
                     LAHFHRENPIVEGMDREELKSRLAERMHLKSGKKAEALIAELEKRKVITIQGSVVSVA
                     GFTVSYSDEASQMMTDMENIYKKAGIEVPSTDELVGAYKDRKQARQVLSELTKKGILV
                     KAGTGVLMHKEHWDRALNILREHLAANPQITLGEFRDLLGTSRKYAVMLLETYDQMKI
                     TKKTGDVRVPGGK"
     gene            84049..85137
                     /gene="yedE"
                     /locus_tag="ACZPCR_01160"
     CDS             84049..85137
                     /gene="yedE"
                     /locus_tag="ACZPCR_01160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016438391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YedE family putative selenium transporter"
                     /protein_id="HIR1229530.1"
                     /translation="MNNSSLTTRLILGAVLGAAAAALAFLGNPANMALCIACFIRDTA
                     GSMKMHSAAVVQYFRPEVVGIVCGAFLISVATKEYRSTSGSSPMIRFLLGVIMMIGSL
                     VFLGCPLRLLLRLSAGDLNAVVALPGFVLGIFTGTLALKRGFTLGRAYPTKNSSGFVL
                     PGLLVFLFVLSLTTTLFVSSESGPGSKHAPIAAALIAGLVFGAVAQKSRTCFAGGFRD
                     VILMRNFDLLSVLGGLFVVMLVFNLATGGFKLSFAGQPVAHSQHIWNFLGMYVVGFAA
                     VLAGGCPLRQLVLAGQGSSDSAVTFLGLLVGAAFCHNFGLAASAAAAATETAEAVAGG
                     PGPAGKAAVLICIAVLFLIGFLPSREKK"
     gene            85199..85405
                     /locus_tag="ACZPCR_01165"
     CDS             85199..85405
                     /locus_tag="ACZPCR_01165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002577062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA family protein"
                     /protein_id="HIR1229531.1"
                     /translation="MYEVDARGLSCPEPVMLTADAIKKHGNETIKVLVSEVHTRQNVE
                     KYAKSHGKSVSVTEKGTEFELTIK"
     gene            85467..85703
                     /locus_tag="ACZPCR_01170"
     CDS             85467..85703
                     /locus_tag="ACZPCR_01170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HIR1229532.1"
                     /translation="MRKKEPTLIITFHTTADAIALEKACRETGRPGRMIPVPRELSAG
                     CGLAWCTSPDHAEDFKSFLEEKGLVWEAFEEILY"
     gene            85730..86881
                     /locus_tag="ACZPCR_01175"
     CDS             85730..86881
                     /locus_tag="ACZPCR_01175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009461358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HIR1229533.1"
                     /translation="MIYFDNAATTMTKPKQVAEAVAMALTNFGNSGRGASEASMDASR
                     IIFSTREKLSRLFHGGDPKQTIFTCNATESLNIAINGLIGPGDHVITTVLEHNSVLRP
                     LFHLAEQGTDLSFVTCNNKGRLKYEEFEKHLKKNTKAVVCTHASNVTGNVVDLKQIGE
                     FCRKHGLLFIADISQTAGAYPVDMEVFQADVLCFTGHKGLFGPQGTGGLCVREGVDIA
                     PFKRGGSGVHSFLKEHPAEMPVRLEAGTLNGHGIAGLSAALDFIEETGVENIHSRENA
                     LMLQFYEGVKDIPGVIVYGDFESSLSRFRRTAVVSLNIGDYDSSRVSDELETVYGIAT
                     RPGAHCAPLMHQSLGTVEQGIVRFSFSWFNTEEEVEAAVRAVKELAEDE"
     gene            complement(87110..88711)
                     /locus_tag="ACZPCR_01180"
     CDS             complement(87110..88711)
                     /locus_tag="ACZPCR_01180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HIR1229534.1"
                     /translation="METGYGFLALVPPVVAISLCFATKQVLISMFAGLFAGSLIMSHW
                     NPFAACAFALDKIAVNMSGNIVLLLFTLFMGVGISFIWKLGGSFALAAAAKKRFKKRR
                     SVCLGTWGLGIACSVNDCLAAAIDGNVFRDICKDYRISSEKFSYVLDATAAPAAAFFI
                     SDWIAYQIGMIGQGLDAAGITGYTPVAAYIKTLPFNMYSIFTLLFVGMLMYTGRDYGP
                     MLKAEARCLQTGEFNRSGAKPMLDVGSELGEAKQTKPMIRSFVLPIVVTFAVIIFGII
                     YTGWTSPDRTGSGIMDIFNVCDVQLALYWGSFAMAVTGIVIALASRIMTFDETMTTIV
                     DGFKLMALTGAILVLAWSLADVTKSMGLGDFVAHYVGGAIPTGFLPVLVLLCSMLIAF
                     ATGTSWGTMAIMTPLAIQLGYAVTGDAEFSIGMCGAVLSGAIFGDHCSPVSDTTVMAS
                     LFSGADHIDHVGTQIPYTCTVGAVIAVLYVLYGFFRISPVIMIPAGIIALYFLQIILH
                     NIFMKKYGIDPNYTKTMTEDHVMTN"
     gene            complement(89051..90766)
                     /locus_tag="ACZPCR_01185"
     CDS             complement(89051..90766)
                     /locus_tag="ACZPCR_01185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 interaction domain-containing protein"
                     /protein_id="HIR1229535.1"
                     /translation="MTQLESVRSGIEHFVSAAAEAFRVEAAIFNQQSSLFYCTPTYLK
                     KKGNTVHYAFIQDVIVNGSVLVTEPGKMPACIGCRFNEHCPSTMEILCCIHSGTDVAG
                     VISFTSFTKEGQKRISENTEVYLNAITKLSSLIGEYLQQFSEGSAAADTEKLIESLMS
                     LCEQPLLLTDPNGVVLRYNSLADKVLKFCNVSSTSLRQIFSEDMARRITSGNDLFEKK
                     ASIGENTAKVTTRSIYSQNHLHSILVRLSNEFYESLPESGAFERLIGSSRAFVHIQNL
                     IKRVADSPTPILITGETGTGKELVARSFHEQSRRNKYPFVAINCSSIPENLFESELFG
                     YEEGSFTGAKKGGKMGRIEMAQGGTLFLDELGEMPLSVQPKLLRVLQEYELERVGSTK
                     KIHLDIRIVAATNRDLREMIKEGKFREDLFYRISVINVKLPPLRDRKEDIIPISLNYL
                     ERLKTKMTTPLRTISPEAEQAFLNYSWPGNIRELQNVVEYAANLCDSDTLTLADLPEH
                     MRGLEECPDTEKQKEAPLPDSQEKQILYLLSAYGHTLEGKKKIAADLGISLRTLYRKL
                     NKMNL"
     gene            91210..92007
                     /locus_tag="ACZPCR_01190"
     CDS             91210..92007
                     /locus_tag="ACZPCR_01190"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HIR1229536.1"
                     /translation="MITKKDPLNLTGKVAVVTGGSSGIGLGVVEILSAYGAKVAMVDI
                     SPKGEEKAEELRQAGRDVTFFKCDVTNEEQVKATIDGVVAKYGRIDVLHNNAGVTVRK
                     TIADLTEKEWDFVLDVGLKGLFLFSKHAIPVMAANGGGSIINTGSGWGLKGGDLAAAY
                     CAVKGGIVNVTRAMAIDHGPQNIRVNSVNPGDTDTAMLRDEGKQTGAVKEGASQMDAY
                     LADCGTSRPLARIGMPEDIANAVLFLASDLSSWITGAALVVDGGGIA"
     gene            92113..93504
                     /gene="gcvPA"
                     /locus_tag="ACZPCR_01195"
     CDS             92113..93504
                     /gene="gcvPA"
                     /locus_tag="ACZPCR_01195"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004375 - glycine dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_process: GO:0006546 - glycine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HIR1229537.1"
                     /translation="MKGYASHPYIPNSVPEIQEEMLHEIGMSSLEELHKNVPEILKLK
                     ENMNLPKAFGSEYELKRHVERVLSKDTDCHKNLNFLGAGCWQHYVPAICDEINGKGEF
                     LTAYGGEPYNDEGRFQSLFEYASMVAELVDMDVVNVPTMDWAQAAATTVRMAQRITNR
                     SVVLVSEIIDPQKLAVMKNYAESVIKFETVKATAQGTLDLEDLKAKLNDNVIGVYFEN
                     PNYLGIIEPNGQAISDAVHAAGGLSLVGVDPISLGVLSTPPTYGADIVCGDLQPLGIH
                     MYYGGGQSGFMATTDDEKFVMEFPSRLFGIAPTSEPGEYGFGDVAYDRTSFGHHREHG
                     KEYVGTQSALWGITAGVYLATMGPKGMAEVDELIMANAQYAAKKLAEIPGVKVNPFGG
                     AFFKEFVVDFTATGKTVEEINKALLAKGIFGGKDLSKDFPNLGQSALYCVTEVHMKED
                     LDTLAAAIAEVIK"
     gene            93528..95093
                     /gene="gcvPB"
                     /locus_tag="ACZPCR_01200"
     CDS             93528..95093
                     /gene="gcvPB"
                     /locus_tag="ACZPCR_01200"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004375 - glycine dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_process: GO:0006546 - glycine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HIR1229538.1"
                     /translation="MKRIDRSSKVRTKFHQAKWDEPIIYELSTPGERGILVGAPEEEV
                     AKEVEGTAAIPEGMKRSTKLNLPEMSQSRVLRHYARLAQQTLGADVNIEIGQGTCTVK
                     YSPKVNEQLSALIREYHPLQDPSTVQGMLQIFHETDKYMCEISGMDHFTFQPSGGSQG
                     IMTMASLIRAYFKDKGEDRNEIITTIYSHPSDAAAPAVAGFKIIYLQPDPKTGLPTLE
                     QLKAAASEKTAGYIVANPEDTGVYNSHVKEFVDYIHSIGGLCAYDQANANGLLGVTRA
                     RDAGFDMCFFNLHKTFSTPHGCGGPACGATGVQKDLVKFLPAPVVDYDGEKYFLNYDI
                     CANPSAVGKVREWYGVAEVVLKAYCWIRSLGAEGLYQVAKTAVLNNNYMFKKLMELPE
                     VSAYYQDGNNQRIEQARYTLEALEKETGIGTLDIQRRMMDFGMHYWTSHHPFYLPEPM
                     TLEPTETPSKKDIDEYIETLKYVFKEAHENPEVIRTAPHRSVTHQVDESGMDDPAKWA
                     TTWKVYQRKYNED"
     gene            95340..96470
                     /locus_tag="ACZPCR_01205"
     CDS             95340..96470
                     /locus_tag="ACZPCR_01205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-NAD kinase family protein"
                     /protein_id="HIR1229539.1"
                     /translation="MKKLGLLINPVAGMGGSVGLKGTDHMVEEAIRRGAKPRANDRVR
                     QALKELLEIKNKLEIVTCPGDMGEDTAKSMGFRTTVLHTGGRRSLKDLFDSSRTDTIV
                     LSKAMEEAGVDLLLFAGGDGTARDIYEGVGTELPALGIPAGVKIHSPVYAKNPQSAGD
                     LAKLWLTGKVTKTAEQEVLDIDEELYRQEIINTRLYGYLSVPLEHVFTQNRKAPTPLS
                     ETASIESIAHEIVEHMEEDTYYLIGAGTTTRGVMQMLGLKNTLIGVDLIRNKELVAND
                     IYGDKILDFIKGKKTKLIVTVTGGQGFLFGRGNQQITPEVIREIGKENIIILATKAKI
                     AEFHHQPFLVDTPDEELNKELCGYYRVITAYGEFTMCRVSES"
     gene            96781..97623
                     /locus_tag="ACZPCR_01210"
     CDS             96781..97623
                     /locus_tag="ACZPCR_01210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid ABC transporter
                     substrate-binding protein"
                     /protein_id="HIR1229540.1"
                     /translation="MKKKMLALSMAVLMAASLAGCSSGAKETETTAAASEAGAETAAE
                     SEGETAAEDAEEEKTAEGGTLIMGTNATFPPYEYYEGDEIVGIDVEIAQAIGEKLGME
                     VTVEDMEFDALIPALASNKVDIVAAGMTVTPERQESVNFTDTYATAAQVIIVKQGSDI
                     ASSEDLNGKILGVQMGTTGDSLASEIEGAQVERFNKYFEAIQSVLQGKIDAVIIDSAP
                     AKAFAEKDENLVILDEALSSEDYAMAINKDNTELLDKVNAAIAELDEEGTLDEIVNKY
                     IPAE"
     gene            97648..98340
                     /locus_tag="ACZPCR_01215"
     CDS             97648..98340
                     /locus_tag="ACZPCR_01215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006776637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HIR1229541.1"
                     /translation="MWNQFVDTFTRNFIDGGNWHYIAEGLLNTIKITFFAVLLGIVIG
                     LIVGTIRSTYDKTHKLKALNFLCNIYLTVIRGTPVLVQLLIIYYVIFASVRIDKVLVA
                     VLAFGINSGAYVAEIFRSGILSIDNGQFEAGRSLGFNYPQTMWYIVMPQAFKNVLPAL
                     CNEFIALLKETSIAGYIGIQDLTKGGDIIRSRTYSAFMPLLAVAALYLIIVLIFTQLI
                     KILERRLRQSEH"
     gene            98330..99079
                     /locus_tag="ACZPCR_01220"
     CDS             98330..99079
                     /locus_tag="ACZPCR_01220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HIR1229542.1"
                     /translation="MSTNHTEQPLIQVKHLDKSFGSLKVLKDVTVDIYKGDVVCVIGA
                     SGSGKSTFLRCLNRLEEPTGGQIFFEGVDITDAKTDINKHRQKMGMVFQQFNLFPHMT
                     IMDNLTLAPIKLQGKKKEEIEPEAMKLLERVGLADRANAYPSQLSGGQKQRIAIVRAL
                     CMKPDVMLFDEPTSALDPEMVGEVLGVMKDLADEKMTMVVVTHEMGFAREVATRVMFM
                     DGGSFVEENAPEEFFANPKNERLKTFLSKVL"
     gene            99264..>99616
                     /locus_tag="ACZPCR_01225"
     CDS             99264..>99616
                     /locus_tag="ACZPCR_01225"
                     /inference="COORDINATES: protein motif:HMM:NF042595.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6756 family protein"
                     /protein_id="HIR1229543.1"
                     /translation="MFIRNEIERVIKENCIERSRCFECSKIMYSSIIKKIEQTFVLHG
                     GDIHWSNMGHGFNPKLQCKTRDISKDRMWVARLPQILPEREKFVYALFEDRKNYQPKY
                     WVYEMGIPELICIIA"
BASE COUNT        27562 a        21150 c        28036 g        22858 t
ORIGIN      
        1 gatattggct tgatttgaaa caaagtatta aaagcgaagg cattatcaat ctgttttctg
       61 atattaagga ggaattttcg ctgtttgatc cgaagttcct tgaagaagta agcaagatga
      121 aaaaaaatct ggcgattgaa cggttgagaa agctaattgc ggagcaggtg ccgatatata
      181 gaagaaccaa tgttgtaaaa tctgaaaagt tcagcgagat tatgcagaaa gctgtaaatg
      241 cgtatcttaa tggtatgctt accaacgaag aagtaattga ggaaatgcag aatcttgcaa
      301 agcagttagc agaggctcat aaagagggag agcagttagg tctgacagca gatggactgg
      361 cattctatga tgctcttatc aagccgcagg caattaggga tttctatgaa aatggaaaga
      421 catgattctg gaataacgat aaaagacttg atttattagg gggaatggtt tatggcattg
      481 catgaaaata ttaaaaattc cagagaactt gaatttgctg tattttgtat tgaaaatata
      541 gctgcaaggc tgggggtgaa tgcagagcgg gtttatgagg catttacaga aaaaagcgat
      601 atattaaatg gctacattgt accggaatat gaaatacttc atacgcagag caaggagtat
      661 attgtagagg atcttcttga cgtgatgaaa gaaagagggg tggaggtatg atactctatc
      721 atggttctta tctggaaatt gcagagccgg acttggtaca ttcccgcctt aatgtggact
      781 tcgggcgtgg cttctatgtg acaccgttgt atgagcaggc ggagaagtgg tgtggcaaat
      841 gataaggtat tcaatacggt ggaactcttt tttgagagat tgattgacaa ggcagaggca
      901 atcagccgtc tgcgttatga aaaaccgaac ctgcagatat gttttcgtac agagaaagcg
      961 ttgggacttc tgcattttga agggagtgaa caggtatgaa tgcaaacccg attttacttc
     1021 aaaaaaaata tagtcgtgtg attgagtgct ttgcaagaga gcaggggatt tcgctggatg
     1081 cggcattgga ctttttctac cattcacagg tttatcagct gatccgggat ggtatttctg
     1141 atatgcactg tatgagcgac gcatacctgg cagaggaact ggaacaggaa tatcagggga
     1201 aagactaagg aggtaaaatt gtatgattaa aatccttttc atctgcctgg gcaacatctg
     1261 ccgttctccc atggcagagt ttgtcctgaa ggacatggca gccagacgtg gtctggcctc
     1321 aaagttttat attgcctccg ctgccaccag cgcggaggag cttggaaatc ccgttcaccg
     1381 gggaaccagg gagaagctta gagcctgcgg catctccaca gccgggaaat atgcggttca
     1441 gatgaagcgg caggactatg aggactacga ttaccttctg ggaatggagg agcgaaatct
     1501 ttccaatatg cgccggattg ccggaggcga tccggatggg aaaatgtatc ggctgctcga
     1561 tttttcacca aatcccagag atatcgcaga tccctggtat acaggcaatt ttgacctgac
     1621 ctatgacgac attgtggagg gctgcgaggc gtttctggaa tttctcgcaa aggagcatcc
     1681 tgaaactttc cggtaaatat cgtattaata ttttttagaa tcaaaaatgc gccttagccg
     1741 tcggttcaga cagctgaggc gcgttttctg cgtttttctg cccattcctt tacgcatcgg
     1801 tacaggggca gcaggtagag atagaaggcg aagaaaaagc ttgcagtccc ggctccgatg
     1861 gcggccaggg gaacggaacc tgcgatggac catggaatca gggccgccag aaggatgacg
     1921 gaatcttcca gatccagggc caggtcctcc ggcttctcat attcgccctt gcacagctcg
     1981 caggtcagca tggaggccag cgtctggttg cagctgaaca tggaggtgac gatactggcc
     2041 gtgcagacgg ccgggaaacg ccccagcttt ccggacagac ggcggatgag actctgaatg
     2101 ttggttaaaa gtcctgtttc atccagaagt cccagatagg aagaggaaat cattacaatt
     2161 aaactgacct cgaccatgga aagaaagccg cctccggaaa tcagaggaat cagttcactg
     2221 tctccttccg ggtgaaagcc cagcatcatg gcggagagaa cggcggacgg cgccatctgc
     2281 tgaacgaaga cgcacagcag gaagctgagt cctgcgctca aggccatcac tgcttttaca
     2341 tcccatttca tcatgcagaa aatgagaatg acagccgcgg gaacagaggt ataccatggc
     2401 agggcaaaca gcctgggaaa ttcttccatc agggattctg ttccggaagc gcttccgccg
     2461 ctttttccaa ggaccagata cagaaggcag gtcaggacaa agggcaggag acaggaacga
     2521 aacatccgct taatattgtc atagagcttc gtctctgtca gagaggccac caggctggcg
     2581 ctggaggaca tgggcgaaca gcggtccccg aagaagatgc cggagagaac ggctcctcct
     2641 gtcagggtgg gggaaatacc gtttaacctg gctaaaatca tacagatcac gcccactgtg
     2701 ctggccgttc cgaaggaggt tcccatcagg aaggaaacca ggcagcacag cagaaacacg
     2761 gatatcacga aaaaggaagg attcataatt ttcatgccgt agtaaacaat aaaagggatg
     2821 gttccgcagg ctctccacag ggcggtgaga aagccgataa gggcgaaaat aatcagaata
     2881 tttccagatt tttttatgcc gatgcagagc agccggacaa tgtccctgac gtttattttc
     2941 tggtacaggg cgtatccggt aaatagaaga agtcccccta agagggcata gaccagtgag
     3001 aatccagcag ccagacacag aatgaggcag ccgagaaagc cggccagcac aagcgtttct
     3061 atcataatat aatcttcctt aattataatt tttttgaaac gttcatttcc ccggatttgg
     3121 ggaaccattt aagtataata caaaggaatt tcaggcgcaa gcagaacgtt aaaaactgca
     3181 gtttttccct gtttgtaatc atgtaagaaa agattttgta ttcatgtgtc tgccataggc
     3241 gtcaggaaag attaagaaaa agatctgtta ttttccattc aaagaatggt acaatagagt
     3301 atagctgaat ttcagctgga tgcgaggtga tacgtttgaa gacagcggat gaaacggcgg
     3361 ctcctgtggt gtttcatgtg gatgtaaaca gcgcgttttt atcctgggag gcggtgtacc
     3421 gtatccggga gctgggggcg aagaaggatc tgcgggacgg gctgtgcgcc gtaggaggag
     3481 accgccaggc caggcggggt attattctgg ccaagtccca gtctgcgaag ggatacggag
     3541 tccgcacagg agagtctatt ctggaggcaa agagaaagtg tccggatctt aagctggttc
     3601 cggccaatta ccacctgtac aggcagtcct cagaggcctt tataaagatt ttgaaggaat
     3661 attcgccgga ggtggagcag tacagtattg acgaggcctt tatgaacatg accggcatgg
     3721 aaaagctgtt cggtccgcca agggaggcgg cggagagaat ccgggagcgg attttccggg
     3781 aactgggttt tacggtcaat atcggcattt ccaccaataa gctgctggcg aagatggcgt
     3841 cggattttaa gaagccgaat ctggttcaca ctctgtttcc ggaggagatt ccggagaaaa
     3901 tgtggccgct tccggtgcgg gagctgtttt ttgtaggaag atccacagag gccagcctga
     3961 agcgtctggg aatccgcacc attggagacc tggcgaagac ggatccggag cttctcaaat
     4021 atcatttgaa gaagcacggg gaggtgatct ggaatttcgc taacggcagg gacgccggag
     4081 tgattgagac ggaggagacg gagaataaaa attatggaaa cagcaccacg attccctttg
     4141 acgtgacgga cgaggggaca gccaggattg tgctgctttc cctggcggag acggtgggac
     4201 ggcggcttcg ggccggccat gtgaaggcgg aggggatttc tgtgacgatt aagaacacag
     4261 atctgcattc tgtctcccac caggcggtgt tcgagacgcc tacgaatatt acggaggagg
     4321 tttacagggc cgcctgccgc ctgtttgagg agctgtggga cggatccgcc atccgcctgc
     4381 tgggcatttc caccagccgg atcaaggagg agggctgcgc ccgccagatg aatattttcg
     4441 agggagaaaa gtatgagaaa ctggagcggc tggatcacgc ggtggatgaa atccggtcaa
     4501 aatttggaag cggagccgtg atgcgggctt ctttcctgga acagccggtg gcccatatgg
     4561 ctggcaggga agtccgggcg gagaagaagc tggactataa ggatattgaa attgagtaaa
     4621 atcaggagca ggacagggac aagaggatga agagagagat tgtatttaaa atggagcgcc
     4681 ccggcctggt ggaggaaggc caggtagtgg aggtcagcga gtcggtgacg ccgtttaacg
     4741 tcaactatat gatagagccg gcggtggcca tgtctgggct gttccagctg aacaaccgtc
     4801 tgaaggcaga ccatggaacg gtaaagaaaa tcgaggagaa tgccagaggc tactatgtaa
     4861 ccgtggagtt tgaagaggag gaatcatgat gcagaagata cccaaggatc cgattatgtg
     4921 cttaagcttt gtaaatacgc agctgcggga cgcctataac agtttagagg agctgtgccg
     4981 cgcctttgat gtaaagaaag aggagctgga agagagatta gccgccgttg gatatgtata
     5041 tcagccggag ttaaatcagt tccggtagag cggcgctttc cggcagatat gcctctttct
     5101 gcggacagat gaagaggaaa gccaggggag ggatcatttc ttgagagaaa gggggaggag
     5161 cggtgcctga cctgttttca atagtcatgg aaacaatttt ttcagtgtgg gactggattc
     5221 cggaacacct gatatttgtg aatctgctgc tgtctgtggg aatcgtgttt ttccagcgca
     5281 gggatccgcg gacggtctgg gcctggcttc tggctctcaa ctttatcccg gtatttggaa
     5341 tcatttttta tctgctgttc tgccaggatt ataagaaaaa cagaatgttt cggattaagg
     5401 aggtggagga tcggctgaaa tgtccggcaa agctgcagga ggactgtatt aaaacaaggg
     5461 atctggctct tttaggggat ctggctgcag attacgaatc gctggttctc tataacctgg
     5521 acacctccgg aagcgttctc accatgaaca ataaggttca gatttttgct gacggggagg
     5581 agaagttcca gaagctgaag gcggatctgg agcaggccag agaatacatc cacatggagt
     5641 attacattat aaaaaatgac gaggtgtttg actccattgc ccccattctc atccgaaagg
     5701 cagaggaggg cgtgcaggta agaatcctgg cggacggtat gggaggacgc ttcatgccgg
     5761 gcagcagatg ggaaatcctg cgccaggccg gagtccaggt gggcattttc ttcccgccgg
     5821 tactgggccg cctgaatttg agagtgaatt atagaaatca caggaagatt gtggtgatcg
     5881 acggccgctg gggctatgta ggcggcttta acatcgggcg ggaatacgtg tcaaaggatc
     5941 cgaagtttgg ctactggcgg gacacccatc tgaagctggg cggcgaggct gtgttaagcc
     6001 ttcagatacg gtttgccctg gactggaatt atgcggtggg ggaaaacctg ttccaggatg
     6061 cccgatattt tgaacttcac attcccacag accggcctga tatgagggac gagtctggaa
     6121 aaatctcctg cgtccacatt ccggaggtgg gaatccagat cattgccagc gggcctgaca
     6181 ccatgtaccg gcagatccgg gacaattatc tggagctttt ccacaaggcc aggaagcaca
     6241 tttatattca gacgccgtat tttgtgccgg acgacgccgt cctgtcggcg ctgcagattg
     6301 cggcccggtc cggggtggag gtaatgctga tgattccctg caagccagat caccccttcg
     6361 tctactgggc tacctactcc tatgtaggcg accttctcag agcaggggcc aggtgcttta
     6421 cctatgagaa gggatttctc cacgccaagg gcgtctgcgc agacggccag gtgtgctgtt
     6481 atggcacggc caacatggat atccgcagct ttgaactgaa tttcgaggtc aacgcggtga
     6541 tctataatca gaagattaca gaacagatgg aagaaatttt cataaacgat ctgaaatcct
     6601 gccgggaaat caccagagaa acctatgagg caagaggtct cgtcacccgg tttaaagaac
     6661 agtgcagcag gctgctgtcg ccgcttctgt agaagaggca gaaaccgcct atgtacgagg
     6721 aaaaattccg gtgactttcg gtggagcgag gaaaagtaag aaaagaaaaa ttctggtgac
     6781 tttcagtgaa cagggaaatg tttcttttct ttcttatata aaaactaggt gtaccaggga
     6841 agggggaaag ttttccagcg actttcagtg gagcgaggaa aactttccac ccttcccctg
     6901 catttcacct attttttcca catttcttac ttgtatttgc gcctcccttt ctatataata
     6961 ggtaagacag agaggtgacg acatgataag attgatactg gtagcaagct ttgtaatcgg
     7021 ctttttgctg tttttctcag gcgttttgta ccggctgaag aagctggggc agacagactg
     7081 ggagacggcg gagtggaaga gcttaaatat cgtaaggcgg gccttttccg tgattctcaa
     7141 gacagcggga gtaaaggtga ctgtgaaggg agcggaacac attccagccg acacgccggc
     7201 gctttatgtg ggaaaccaca gaagctattt cgacattctg gtgggctaca ccaccgttcc
     7261 ggggctttta ggctttgtgg caaaaaaaga gatgttaaaa ataccgcttt tatcccagtg
     7321 gatggtgcag gtgaactgcc tgtttatgga ccggcagaat gtgaaggaag gcctgaaaac
     7381 cattctccag ggcattgaga aaatcaagcg cggcgtatct atctggattt tcccggaggg
     7441 cacgagaaac aggaacgaga aagagacgga tcttctgcct ttcaaggaag gaagcctgaa
     7501 aatcgcggag aagacaggct gcccggtgat tccggtggct attacgggga cagcggacgt
     7561 atttgagaag catctgccgt ttatccgtcc ggctcatgtg acaatcgagt ttggagagcc
     7621 gtttttcgtg aaggagcttc cgccggagca gaagaaattc ccgggagctt acacgcgcga
     7681 cagaatactt gagatgttgg agaaggaaca gcatggactt acaggagatc aggaagcagc
     7741 tggacagcat tgacgcagag tttgtcaggc tgtttgaaaa gagaatgaag ctctgcgccg
     7801 atgtggcgga gtttaagata cggacgggaa aggccgtcta tgacccgaag cgggagcagg
     7861 agaaaatcgc cgccgtccgg agcatggctg agggcgagtt tatgaaagag gcagtgggag
     7921 agctgtttct gcagatgatg actctcagcc gccggtatca gtaccggctg atggagcagg
     7981 tacagagcgc ctctgacttt gggtttcaga gagtggagga cattgagaaa aagcaggtgc
     8041 ggatcgctta ccagggactg gagggagcct acagccacgc ggcggtgatc cagttcttcg
     8101 gggagcaggc agatatgttc cacgtgcgcc ggtttgagga cgcggcgaag gccgtgtttg
     8161 aggggcgggc ggactacgca gtgcttccca ttgagaattc ctcagccggg gcggtgtctg
     8221 acaattacga cctgctttta aagtatgaga attacattgt ggctgaggtg tttgtgccgg
     8281 tctgccactg ccttctgggc actcgggacg cggagctttc cgatattaga accgtgcttg
     8341 cccatcctca ggcgctgatg cagtccagcc agtatctgaa cgccagggag gactggcggc
     8401 agctcagcgt ggagaacaac gcggtggcgg ccagaaaggt cagcgaggag gctgataaga
     8461 gccaggcggc tgtggccagc cggacggcgg cggagattta cggactgaag gtattagcgg
     8521 agggaattaa ccacaaccgc gagaatacca cccggttttt aattctctca aaacatccgg
     8581 tttaccggaa ggatgcggac aaggtcagca tctgctttga gcttcctcac gagagcggaa
     8641 cgctctacaa catgctgaat aattttgcat tcagccacct gaatatgcgc atgatcgagt
     8701 cccgccccat tccgggcagg aactgggagt accggttctt cgtggatatc gagggaaatc
     8761 tggacgatcc cgacatgatc aacgcgttaa agggaattgc cggagaggcg aaccatatga
     8821 gaattctggg aaattattaa agagaaacac gcgtaataca cgcggtaagg ggcgcctgaa
     8881 gcaggctggc atttccatgc acagtccggc cgagggacgc cccttcttct gtaaagaagg
     8941 ggcaagagaa ctgtaaaaga acagtaaaaa tgggaagaga aaggattttt gggaatgaag
     9001 cagcatctga ttctgtatag aaatttaaag tatggggagc tgttagaccg catgggaggc
     9061 cttctggaac agtacggagg ggcagctcag gaggcggccg ggcagaagga gaccggacaa
     9121 gaggcaggcg gacaggagac agccgggcag aaggcagacg ggcaggaggc ggaggaggcc
     9181 tggtgcgccg gggaactgat tgccctagca gatgcttacg gcttcgaggg gaatctgtgg
     9241 ctctgctttc tggccctctg tctggcggaa aacgaaaatc cctacagcat tgcctgcgag
     9301 atccgcgggg aggcgtccgg aagcctaaat caactggctc tccacgactt ttccgtgttc
     9361 tggcagctca gccggcagga tttggggact ctccctatga aggaggtatg gagcctggcg
     9421 gcagattatc atgggccggg gaagaaaagc cgtcagtttg acagccgggt gagggacagg
     9481 attttaacgc tggccgcgga gcttttgcag gcggaaagcc cggaggactt cagaggcagg
     9541 acggcagagt tttaccggga gctgggagtg ggaaaatttg gcttaaatca ggccttccgc
     9601 gtgacgggag ctgagggaaa cgctcagatt gagcctatta ccggcgtaga agaggtatcc
     9661 ctgaaggatt tggtgggata cgagcggcag aagaaaaagc tcatcgaaaa tacagaggca
     9721 tttatcgagg gcagggaggc caacaacgtg ctgctgttcg gggacagcgg aacgggaaaa
     9781 tcctccagca tcaaggcggt gcttcacgag tattacggca gaggcctgcg catgatagag
     9841 gtatataagc accagttcca gtgcctggga gagattttgg agcaggtgaa ggacagaaac
     9901 tataaattta ttatctacat ggacgatctc tcctttgagg agtatgagat tgagtacaaa
     9961 tatctgaagg caatgattga gggcggcctg ggaagacggc cggacaatgt gctgatctac
    10021 gccacctcca accgccgcca tctgatccgg ggaaagttca gcgacaagag agagctggac
    10081 gacgacctgc accagaacga cacagtgcag gagaagctgt ccctggtggc ccggttcgga
    10141 gtgaccatct actacggagc gccggacaaa agggaattcc agcagattgt cagagctttg
    10201 gctgccagac ataacctctg catgccggag gaggagctgc tgttaaaggc aaatcagtgg
    10261 gagctgagcc acggaggact gtccgggcgg acggcgtccc agtttatcac ccatctgctg
    10321 ggaacggaac agatacagga ggaaagctat ggcaattaaa atgtttgcgg caatcgacgt
    10381 gggatccttt gagctggaaa tgggaattta cgagatttcc cagagctttg gaatcaggca
    10441 ggccgaccac gtccgccacg ttcttgccct tggaagggag acctacaatg acagaaaaat
    10501 cagctacagg ctggtagagg agatgtgcca ggtgttaaaa ggcttttccg agattatgaa
    10561 aagctatcgg attaccgact accgggctta tgccaccagc gccatgcgtg aggcgaaaaa
    10621 cagccagatt gtcttagagc agatccgggt gcgtaccggc ctgactgtaa agtccatcaa
    10681 taactcggag cttaggctga tgacctacaa ggcggtggcc tccaaggacg ccgctttcca
    10741 caagattgtg cagaagggaa cggccatcat tgacgtggga tttggaagca cccagatttc
    10801 cctgtttgac aaggacaccc ttgtatccac ccagaatgtt gtcctgggcg ggctccggat
    10861 ccgggaaatg atctcccact ggaatttaag ccccagggag acagttccgg tgatcgagga
    10921 gctggtggac aacgagcttt accccttccg ccggatgtat ctgaaggaca gggagattaa
    10981 gagtttgatc gccacaggag agagcattct gtttatggcc agaagcggaa tccgccatat
    11041 ggagtcggac cgggtcagcg cagagcagtt taagagcttt taccgaaagc tcttgtccat
    11101 gactgcagaa gagatcgagg acgaatttgg catagacgga gaatacgctt ctatcctggt
    11161 gcccagcgcc gttatttacg gacggattct ggagatgacg ggagccgaga cagtgtggat
    11221 tccgggagtc agcctctgcg acggcatggc agcggagtac acccaggaca ggaagctggt
    11281 gaagctgcgc cacgatttca acggggatat cctgtcctcc gccagaaata tggcgaagag
    11341 gtataaatgc cacggagatc acattcagga ggtggagcgg ctcagcgcgg agctcttcga
    11401 cgtgacgaag aaataccatg gcctgggaga aagggaacgg ctgctccttc ggattgccgc
    11461 cattctccac gactgcggca agtttatcag ctccagcaga gagacgcaga gctgttatca
    11521 gattatcatg gccacggaga tcatcggcat ttcccacctg gaacgggaga ttgtggccaa
    11581 cgtagtttac tactataacc aggatttcgc ctacgacgcg gtgaagctgg agtccgattt
    11641 gtcccagtac gagggcagcg gactgacccg ccgggcggtg acgattttaa tcgccaagct
    11701 gacggcgatt ttaagcctgg ccagcgccat ggaccggagc cagaggcaga agtttgcggg
    11761 ggcgtccatg gcagtcaggg acggaaagct gttaatcaca gccagctgtc cggagacgat
    11821 tattctggaa cgggcgtcct ttgagaaccg tgcggaattt tttgaggaaa ttttcgggct
    11881 tcagccggtg ctgaagcata agaggagggt gtaaatatgg ctgagggaaa cgagagattc
    11941 tgggaatcta agaattatgt caatagagaa ctgagctggc tggattttaa ctggagagtg
    12001 ctgggcgagg cgaaggataa gaccacgcct ctctttgacc gcttaaagtt cctgagcatt
    12061 acggcgtcca atctggacga gtttttcatg gtgcgggtgg cttccttaaa ggatatgatc
    12121 cacgccaact acacgaaacg ggatattgcg gggctgacgg cagcagaaca gctgacagcc
    12181 atcgaggcga agacgcatca gctggtggag gagcagtacc acgtctacag ccgttccctc
    12241 cttccggccc tgcgccagaa cggcctgaat attattgcct cccatgaaaa tctgaccaag
    12301 tacgagggaa cctatgtgga cagctacttt gaggagatgg tttatcctgt gctgacgcct
    12361 atggcggtgg actcctcccg tcccttcccg ctgatccgca ataaatctct gaatattgcg
    12421 gctctggtga agaagaaaaa gggcgattcg gagctggatt tcgctatggt ccgtgttccc
    12481 agcggccttc cgagggtggt ggtgattccg ccggaggagg gaaaggaaaa agcggggatc
    12541 tctgtgattt tcctggagga gatcatagaa agaaacattg agaagctctt cctgaactac
    12601 gatattatct gttcccaccc cttccgcgtg atgagaaatg cagatctgag cattgacgag
    12661 gacgaggcgg aggacctgtt aaaggagatt gaacgtcagc tgaagaagcg ccagtgggga
    12721 gaggccatcc gcctggatat tgaggagaag gcggataagc ggctgctgaa gatcctgaaa
    12781 aaggagctga aggttacaaa cgacgagatc tatgagatcg gaggccccct ggatctgacg
    12841 gtgctgatga aggtctacgg cctgccaggc tttgaccggc acaaggcgcc gggctacacg
    12901 ccccagccgg ttccggctct gatgaatgag gacgatattt tcaccaatat cagaaaagga
    12961 gatattctct taacccatcc ctttgagacc tttgagccgg tggtgaactt tatcaagaag
    13021 gcggccaggg atccggaggt gctggccatc aagcagaccc tgtaccgtgt cagcggcaat
    13081 tccccgatta tcgcggccct ggccgaggcg gcggacaacg gaaagcaggt gtcggttctg
    13141 gtggagctaa aggcccgctt tgacgaggaa aacaatatca actgggcgaa gatgctggag
    13201 aaggccggct gccacgtcat ctacggcctt ctgggcttaa aaacccacag caaaatcacc
    13261 ctggtcgtgc ggaaggagga ggacggcatc cgccgctacg tccacctggg tacaggaaat
    13321 tacaacgatt ctacggccaa gctctacaca gactgcggcc tgtttacctg cagccgtcag
    13381 atcggcgagg acgccaccgc cgtgttcaac atgctgtccg gctactcgga gccgttaggc
    13441 tggaataagc tgtccctggc gccattatgg ctgagaggca agttcctgcg cctgatccag
    13501 agggagatca agtacgctaa ggagggaaag acggccagga tcgtggcaaa aatgaattct
    13561 ctctgcgaca aggagattat tgcaaacctc tacgaggcct cctgcgcggg cgtggagatt
    13621 aaactgattg tccggggcat ctgctgtctg aaggccggcg ttccaaatct cagcgagaac
    13681 atcgaggtgc ggtccatcgt gggcaatttc ctggagcaca gccggatttt cctctttgaa
    13741 aacgggggaa gagaggaaat ctacatggga agcgccgact ggatgccgag aaacctggac
    13801 cggagggtgg agatcctgtt cccggtggag gacgaggcgc taaaggcccg cctgatccat
    13861 attttagacg tgcagctggc agataatgtg aaggcccatc tcctgcagcc ggacggaacc
    13921 tacaaaaaga agagtctcag aggacgccag aaggttaacg cccaggaaca gttctgcgcg
    13981 gaagccatcg aggcggccag agccatggag gaatcggcgg atcccagaaa caggcgcgtc
    14041 ttcattccca tggaacagta gaaaatgtaa gagaaaagta aagcaatttc gcctcgctta
    14101 tggtaaactg ttgatagaat gcagtttgac gtcagggaac aggagccgtc tcctgggcct
    14161 gacgccgcca taagggaggt tttttcatgt cagaaattaa tatattagtg gtcgacgatg
    14221 agaaggagat tgccgagctg gtggagattt atctggtcag cgacggttac cgggtattta
    14281 aggcggagaa cgccagagag ggcctggaga ttctggaaaa agaaaatatc catctggtgc
    14341 tgttggacat tatgatgccg ggcatgaacg gccttgaaat gtgccgcaag atccgggaga
    14401 ccaacaatat ccccatcatc atgctgagcg caaaatcaac ggatctggat aagattctgg
    14461 gacttggaac gggagcggac gactatgtgg tgaagccgtt taacccgctg gagctgacgg
    14521 cccgcgtgaa atcccagctg cgccgctaca cccagctgaa tccccagagc agcgtaatcc
    14581 aggccgcgaa gaacgagatt tcgattaagg ggctggtgat caacaaggac aatcacaagg
    14641 tgacggtcta cgacgaggag attaagctga ctcccattga attcgatatt ctctacctgc
    14701 tggcgtccaa tccgggccgc gtcttcagca cagacgagat tttcgagaag gtatggaatg
    14761 aaaaggtcta tgaggccaac aatactgtta tggtacatat ccggcgtctg agaggaaaga
    14821 tgaaggagga caccagacag aacaagatta tcactaccgt atggggggta ggctacaaaa
    14881 ttgaaaaata gcgatatgag caggcgtttt cggacgcgca cagtgacgaa tatcttttac
    14941 gccacccttc tcacctgcct gattgagatt tttctcatcg ccaatgtgag catggtggaa
    15001 gaatatttaa gaaaaataga atcagaatct tttctgctgg attttttaga gctgagtccc
    15061 attatggtgc tgatctacgt gcttatcgga atcggcatct tttccgttat cttcctgagg
    15121 ctgcaggagc gccatctgcg gtatctggcc aggatctctg cggccatgca ggacatttcc
    15181 gagggagatc tgaacacggt tgtggaggtg aagggagata atgagttcag cgccatggct
    15241 gtgaacctga accggatggt ggaggacatc agacggctga tggataagga gagggagtcg
    15301 gagcggacga aaaacgagct gatcaccaac gtggcccacg atctgagaac gcctctcacc
    15361 tccattattg gatatctgga gctgctctcc ggcaaggtgg agcttccaag ggagatggag
    15421 aagaagtata ttgatatcgc ctacgccaag tcacggcgtc tggaaaagct gatagaggat
    15481 ctcttcggat ttacgaagct gaattacgga aagctttcca tgaacgtggg aaaggtggac
    15541 attgtgaagc ttctggaaca gcttctggag gaattttatc caaactttgc agagaaaaat
    15601 ctctcctatg agctccacag caatctgccg tcaaaagtga ttgacgcaga cggaaacctg
    15661 ctggcccgcc tgtttgacaa cctgattaac aacgccatca agtacggggc agacggaaaa
    15721 cgggtgctgg tgcagattca ggcggaggag gaaatagtca cagtctctgt aaccaactac
    15781 ggatatgtga ttccggagaa tgagctgcct ctgattttca ataaatttta ccgggtagag
    15841 cagtcccgct ccacccacac gggaggcacc ggtctggggc ttgctatcgc gaaaagcgtg
    15901 gctgagatgc acggcggcag tatccaggta aaaagcgatc tggacggaac cgtgtttacc
    15961 gtgaagttga agacgcattt tgacattaac agggaacagt tcgaggtggc cgagtaggcc
    16021 ggatggcaga gaaaggaagc acagcgccgg ggtgggaagg ctccggcgcc tgggaaagga
    16081 acgatgacag atgatgaggg aggagaaacg agacggtttt ttgggaaaaa gagcaggagg
    16141 aaaggcgctt ccggctcttt ttctgatttt gtgtcttctg acagctgtcc tctggcagac
    16201 gccctttgcg tctctggcaa aggctcagtc ctcagacgtg aaagaggagc aggattcaga
    16261 ggagggagca ggagataggc tgaaacgcca ggtggccatg gaggccgact atgggtttgg
    16321 aaagaaggcc aaggcaggca ggtatctgcc tatccaggtc acttataaaa atcaggagag
    16381 gcaggccttt tcaggaacac ttaaaattct gaccatggaa tccagcaagg aggtctacca
    16441 gtatgagtat ccggtggatc tgggagccgg agaagagaca gaaaaggaat actatattcc
    16501 tctgggcgtt ggaaatgatc agatgttttt aactctgaca gatcaagacg gcaatgaaat
    16561 cataaaaaaa aggctgaagc tggatattcc gtcagaggcg gcgctcctgt ttatcggcgt
    16621 tctcagcgat cacccggaca gcctctccta tctggatggc tgtggtttaa gctacgggac
    16681 gctgcggacc agcgtagttc ccctaagcgg cggtgaagtg ccggaaaatc agctgggact
    16741 tgaccagttt gacctgattg cagtcaatga tttcgactgg aacagcctga cgcacgggca
    16801 ggagaaagcg cttctgtcct gggtgaggga ggggggaact ctgctttttg gaacaggaga
    16861 gcagttagag cgcaccctgg ggcggctgaa aaaggacctg attggcgaaa cgcccgtctc
    16921 aaacctggcc agaactgtag atttgatgaa gcttctggga gaaaacggag gggaggcgct
    16981 ttcagcggag ctgttctgct ctgacttttc tattaaggga ggccgcaagg ctctctttca
    17041 ggagggaacg gctcttctga cacgaaaaac agaacagcag ggccagatgg ttctggccgg
    17101 ctttgacctg gcggacgtgt ccggccagtt tcttcaaaag ccgtcgctgg cggagaaatt
    17161 tctgacggag gtgatggggg agaatacggt tcagtatctg gcccaggatc agtattacgg
    17221 cctgtccagc ctttactatt ccattcaggc gctgatcaat acgggaaatg tggatcgtct
    17281 gcccaattta gggctgtata cggctgtcat tctgctttat attattctta ttggtccagg
    17341 cgcatatctg tatctgaagc ggaagtccct tcagaattat tatatgctca gcgtggcggt
    17401 tctggcagtg ggatttacgg ggattattta tgcggccgga gctaagacca gatttgcagc
    17461 gccctttttc acctatgtga cggtggaaaa ttatgggaaa gaggagctgg agagcgagac
    17521 ctacgtcaat gtgagaagcc cttataacac tccatatacg gtggagctga atccggatta
    17581 cctggttcgc cccattacaa agaattacta ttatgaatcg aatcatccag tcacgtttac
    17641 cggaaatgaa aaatttgaga cggctgttcg aatcgaaccg tcgcagacca ggataaaggt
    17701 gcgggacgca gcggcctttg aaccaaagct gttcagcctg aagcgggagg agaggtcaga
    17761 cagacccgcg ccgtcgggaa cgattcgctt tttcgacggt caggtgacgg gaacggttgt
    17821 gaaccattcg gaggagacgt taaagaacgc ggttctgctc ctctatggaa aagcagtgtt
    17881 tctgggtgag atgaagccgg gggaggagaa gatcctggac ggcctgcccc agctttccta
    17941 tccttccgcc tataagactg ctgtggccca gatggttccc ggaacggatc agtatacgaa
    18001 aacagatatt tcagataaaa actatatgga agcccagagc cagacgaagc tgttgtcctt
    18061 ctatatggaa tcccgcatgg cggagtattt tccggaagcc cgcctgattg ccttcagctc
    18121 cggggaggag gagacagatt tcctggctga caggtactat gtgacaggag gtctcaccct
    18181 tatgacctcc gagcttccgg tggagcaggg aaaggacggc atggtttacc ggtgcgtgct
    18241 ggaacagctg ccgaccgtcc tgtcaggcgt gtatgattat caggggaatt cgctgtatac
    18301 aggagaaccc tccgagccgc tggtattgga gtatcatctg ggaaatgatc tggagattga
    18361 gcggcttacc tttgactggc tgtctccgga gtttattgac aatccaaagt atccgtacct
    18421 ggagcagttt gacggctcga tctacttcta taactacagt acgggaaagc atgatcggat
    18481 ggatttgagc aagaaggagt acagcagaga ggagctgaac ccctatctgt ctcccagcaa
    18541 tacgctgaca gtgaaatatg ccggggagcc gggagaggac gatatctgga atatgattct
    18601 tccagtgcct tatgtgacag ggagggaaaa ataatgctgg aaatcaggga tttaagaaaa
    18661 aaatacggca attttcaggc tctggacggg ctcagcatga caattgaaaa aggagagctg
    18721 tttggcttcg taggcccgaa cggagccggg aagaccacca ccatcaagat tatcacaggt
    18781 cttctgcagc ctgacagcgg cagcattgtc atcgacggca tggacggaat cagggacaga
    18841 agacatctga agcagaagat gggttatgtg ccggactcct tcggcgtgta cgataacctg
    18901 aaggtgtcag agtacatgga gtttttcgca tcctgttacg gtatcgaggg cctggaatcc
    18961 agaaagcgct gcggacttct tctggaacag atgaagctgg aggataaggc ggatttcttt
    19021 gtagacggcc tttccagagg catgaagcag agactctgcc tggccagggc gctgattcac
    19081 gatccggagc tgattgtgtt agacgagccg gcgtccggtc tggatcccag aacaaggctg
    19141 gaatttacca gcattttaaa ggaactcagg gaacagggaa agacgcttct cgtcagctcc
    19201 catatcctgt cggagctgtc ggaaatgtgt accagtattg gaatcatcga gcagggaagg
    19261 atggctctgt ccggcagcat ggagcagatc ctggagcgtg tcaattcttc caacccactt
    19321 ctgattacga tatttaaagg aagagaaaag gccatgtcca ttctccgcag ccacccctgc
    19381 gtgcagacaa tttctgttaa gggggaggag attaaggtgg gctttaatgg agataagaag
    19441 gatgaggcgc tgcttttgca gcagatggtg gacgcagagg tgatggtgaa cggatttatg
    19501 cgggagaagg gaagcctgga gacaatattt atgcagatta cagatcacat gggagaaaag
    19561 gcggtgctgg tacatgaaga tgaatccggt ttataaaaga gaattgaagg tagggagcag
    19621 aagtatccgc atggcggtga ttctgctggc gtttaatggt attttgagcg ccgtggccct
    19681 cttcaatatg tactctgcag tggaacaggt aaaaatgaca gcggagatcc agtattccag
    19741 atttctgcag ctctatgtat ttgtggcgtc cctggaattt attatgctga tgtttatcat
    19801 gccggccctg acctccaaca gcatcagcgg agagagggag aggcagacgc tggatctgat
    19861 gctcaccacc accatgaagc cgggggagat tgtcctgggc aagctggcag cggcttttac
    19921 caccatgctt ctgctggtgc tgtccagctt tcccgtactc tccctggtgt ttgtatacgg
    19981 cggcatcacg gtgacggata tggcccagct gatgctctgc tatgtgacgg tagcgctgct
    20041 ttccggagcg gtcggcgtat ttttttcatc catgtttaag cgctcgactc tggcaaatgt
    20101 ctgcgcttat gtgaccatta tttttctggt agcaggaacc tacggcgcca atatatttgc
    20161 ctaccagatg tcgcagaatg agatcagcag ctatatggat gcagtcgaca atatagcaaa
    20221 gcaggccagt tccggcggaa gcatttacat gctgctgttt aatccggcgg tgacgtttta
    20281 cgctatgatt aaccagcagg ccggggacag cgacgtggcc ggaaccctgg agaggatgtt
    20341 tggggctcac cctcagaact ttgtcctgga acactggacg gagatcagca ttgcagttca
    20401 gattctggcc gccgtgcttc tgattgcggc ggctgtggcc gcggtaactc ccgtctggga
    20461 gaggggcaga gagcgcagga gaggaaaaga taaaaacagc cggcccatat agaaagacag
    20521 acagaaacag acagaataac agaaggaaca atgataaaca gacaggagaa taaacagtat
    20581 gcttagaatc ggatgccacc tttcttcctc caagggatac cttgccatgg ggaaggaagc
    20641 ggaaaaaata gacggaggaa cctttcagtt tttcacgaga aatccaagag gaggcaaagc
    20701 caaggagatc gatccggagg atgtgaaggc atttttagac tttgcgggac agaaggacat
    20761 tgcgccgatt ctggcccatg cgccctacac cttaaacggc tgctctgcag acgagggaat
    20821 ccgcgccttt gccgtcaata ccatggcgga cgatttaaag cggatggaat ttacgccggg
    20881 aaatctctac aatttccatc ctggcagcca tgtaaaacag ggagtggaag ctggcattgc
    20941 gtatatatct gatatgctga atcagatttt aaggccggaa cagaccacca cagtgctcct
    21001 tgagaccatg gcgggcaagg gaagcgaggt gggcaggaat tttgcagagc ttcgggagat
    21061 tctggaccgg gtgcatctga atgaaaagat gggcgtctgc ctggatacct gccatgtgtg
    21121 ggacgcaggg tacgatattg cggaacatct ggatcaggta cttgatgagt ttgaccggac
    21181 gataggcctt tcacgcctga aagccatcca tttaaacgac agccagaatc ctctgggcgc
    21241 tcataaggac cgccacgcca gaatcggcga aggctgcatt gggctggagg cgctggtaag
    21301 agttatcaat cacccggctc tcagaaccct gcccttttac cttgagactc ccaacgatct
    21361 ggacggctat gccagggaaa ttgcgcttct gaagtcaagg tatatagagt agaaacgcat
    21421 ttttattcag cccgctgaac ggcgggctgg tttattctgc aatattctat caatatgttt
    21481 aatttataag tatttcccat cttttcctat tattaaaaat aatgaatgaa atcccgctcc
    21541 tttgtatact gggcagggaa aatacggtat actgttgtgg ttgtcctgag gaaaggaatc
    21601 acaaaaagga gattgggaac aatgagtgag aaagagacaa agggagcgga gtacgatttt
    21661 tatggaaagc ttccgctctg caaggccatc ccgctgggac ttcagcatgt actggccatg
    21721 ttcgtgggaa atttaacccc gcttttaatt atcacaggcg cctgcggcct tacgaatacg
    21781 caggaatttg ccaaccttca ggtggatttg ctgcagaacg ccatgctggt agcaggaatt
    21841 gtgacgctgg ttcagctcta cgctatcgga ccggtaggcg gaaaggttcc gattatcatg
    21901 ggaaccagtt ccggctttat cggagtgttc aacagcgtgg tgggagtcat gggcggagga
    21961 atcctgtcct atggagcgat tatgatggct tccattttag gaggaatttt cgaggggatt
    22021 ttaggctttt tcttaaagcc cttgcgccgg tttttcccgg ctcttgtgac gggaaccgtt
    22081 gtgctttcca tcggtctgtc cctcattgca gtgggagtca attccttcgg cggaggcgat
    22141 aaggcggcgg atttcggaag cgtggaaaat ctgcttctgg gaacgctcgt gctggtagtg
    22201 atcgtcgcgt taaagcacgg aacaaaggga atgacaagct cttcttccat tttgattgga
    22261 attattgtgg gctatattgt ggcagccatt atgggtctgg tgcttccgac caccggcgtg
    22321 acggcggagg gagtggagta cacaaaggcc tgggtgttaa actgggataa ggtggcggag
    22381 gccagctggt tttccatgcc gaaactgatg ccggtaaagc ctgtctttga ctggagagcc
    22441 gtgattccgg ttatgatcat gtttgtcgta acagctgtgg agacagtggg cgacatttcc
    22501 ggagtaacag aaggaggcat gggccgggag gccacggaca cagaactgtc aggaggtatt
    22561 atctgcgacg gtatcggttc cagctttgcc gccctgttcg gagttcttcc aaacacctcc
    22621 ttcagccaga acgtgggact ggtggccatg acaaagattg tcaaccgctt cgccctggct
    22681 acgggagctg ttttcctgat tttatgcggc ctgtttccca agctggcggc actgatttcc
    22741 attatgcccc agagcgttct gggaggagcg gcagttatga tgttctcctc catcgttatg
    22801 agcggaatcc agctgatcac taagaagtcg ctgaccccaa gaagcattac tatcgtatct
    22861 gtggccctgg gactgggata cggaatcgga gcaaacagcg gtattctctc ccatctgcct
    22921 cagagcgtac agctgatctt cggcggatcc ggcatcgtgc cggccgcgct ggttgcgatt
    22981 attctgaacg tgctgcttcc ggcagagaag gaagaatagg gaaaagagat ttaattaata
    23041 tcacaagtgt taagaaaaaa gagacgcttt ccagatgctt aaggcgctgg agagcgtctt
    23101 ttttgcgtct tcacaaaatt tatattgtca ttatttggat aatatactgt tagacattgt
    23161 gttatccgaa tgttaatatg gttttagata aaaagtgggg aggaaagcag tatgcgcaga
    23221 gagaaattag aacgtatatt tccagctttt caggagattc aggacgaaac gctcagagta
    23281 aaatcggagg aagcgatgct tgcggccatg gaggcgggag gctggaatga acagacgata
    23341 aagctttgtc cggtcacatt gaactgggag aactgcgacg tatcctggac agagcatgtc
    23401 agcgatgtga cgagcatgtg cctgatggag ttcgatgggc tggaaaagta ttacaaacgg
    23461 catggggtga gcttcagccg ggatctggtg gcagccggtg cgctgcttta cgatatcgga
    23521 aagctgacag agtttgtttt tcgcgatgga aaggccgttc atggagacaa ctttgaactg
    23581 atgcgccatc cattgtcagg agctgtcatt gcggctaagg caggacttcc ggacgagctg
    23641 gtacacctga ttgccgtcca ttcctttgaa ggagacaagt cttaccagac ggcagaatcg
    23701 gaatttgtac gttccattga tatctttgta tttaactgct ctgtaaaagg gctgaaaaag
    23761 atccacaaaa attaatttga caacggttca aaataaaaaa ggaggaaaag agatgaagaa
    23821 gacattaaag acagctctgg ttttaacagc aatcggcgcg cttgcactga caggctgcag
    23881 cggaaaatca ggggatagtt ccaatcagaa gaaagaggca gcagaaggcg gcggagccgg
    23941 agagtggacg ccggaacgct ccatcaatat gatcgtgccg tggagcgcag gcggtggctc
    24001 tgacctggct gtccgtactc tggttccgta tctggaggag gatttaggcg tcagcattac
    24061 agtcctgaac tctacgggag ccaacggatg gattgcctgg aacgaccttt taaaggcaga
    24121 tccagacggc tacaccatcg cgcagatgaa tattccaacc gtatattcag gctatttaga
    24181 cccgcagcag aacagagatg aaaccctgga cgactttact ctgattgcca acgaaatcag
    24241 cgactggggc tgccttgtag taaaggcggg agacgagcgc ttcccggatg tggagagctt
    24301 tattgaatac ggcaagagca atgagatatt agccggagac aacggcgtgg gaacaaataa
    24361 gcacctggta gctgaaaatc tgaagagcca gattgaggga ctgcagatta cgccagttca
    24421 tcaggcaggc tggagcgata cctatgcagc tcttttaggc ggccatatcg atgtgggctg
    24481 gggctctatc ggagagacaa ttcaggccta tgaggacgga gaggtagaca ttctgtgcgt
    24541 ctttgccaca gagcgttctt ccctgcttcc agatgtgcct acctttaatg agctgatgcc
    24601 ggagtatgat gtggtatccc cgtctgacag aggttttgcc cttccggccg gcgtggacga
    24661 cgcagtttac gaccgctggg tacaggctat ggataactgc attaacaatc cggaatttat
    24721 cgaaaagatg gcagagcttg gacaggctgt caactacatg ggcggagaag agtatactgc
    24781 atatgccaag gagcaggagg cagagatgga aaaattctcc gatatccttg gttggaaata
    24841 gcggcagtta aggaaaaaaa ggagaccgga aaatgaaatt gaaacagatt catgcagagg
    24901 tatggctggg aggaattctc atcatactgg cagttatttt ctacatcatg gcagggcagt
    24961 ttccaaacgc cagcgccgct gtctggccca aggcggttct gatcggcatt atgattctgt
    25021 cagtcctttt ggtgattcac ggcctgcaga tgacgaagga tgcagacgga aacgccgatt
    25081 taggcggagc tgtcttaaag gggccgatgg cttctctggt tatgattgtc gcctatgcgg
    25141 tgtgcatgag ctttacagga tactttgtat ccacagcgat ctttcttccc ctgggaatgg
    25201 ctgctctggg acagagaaac tggaaggcga ttctgggagt gaccgtcggt ctggagctgt
    25261 ttgtctggtt cctgtttgta gtacagctgc agctgagaat gccatagctt gataagacaa
    25321 tagaggtaaa catatgatac aggaaatttt acaaaatttt atgtcgattc aggtctggat
    25381 tggacttgta gtaggcgtgg taggaggcat ggtcgtagga gccatgccgg gcctcagcgg
    25441 tggtatggcg attgctcttc tgctgccggt tacatactcg atggatccgg tagcggcgct
    25501 ggtaatgctg atggctattt acacttctgc tatgacaggc ggttcaatct cagcaattct
    25561 gctgcatacg ccgggtactc cggctaatgc ggcgactgcc atggagggat atcctctcac
    25621 aaagaaggga agaggactgg aggcagtggg aatgtccatg ctgtcctccg gaatcggagg
    25681 ctttgccagc gccctggcgc tcttggttat cgccccgcct ttagcgaagg tcagcctgat
    25741 gttcagcgag ccggagagct ttctgatctc agtgttcggt ctgactgtaa tcggaagcct
    25801 tgcaggaaat tctattttaa aaggacttct gatgggactt gtaggactgt ttttagccac
    25861 agtaggcatg gactctgtga caggcaccct gcggtatacc tttggttttg actctttaat
    25921 gaacggaatc cagatggttc ctgctctgat tggcttattt accatttccc aggtaatgag
    25981 caactgtgaa gattataaac acgcaaacca gtcgattctg gagaagagca atgcaactct
    26041 gggaaagaag atgcttccga ctctcaagga gattccccgt tacatctgga actgggtatc
    26101 cgcttccatc attggtattg tagtaggcat tctgcctgga gccggcggaa atatcggttc
    26161 ctggatcgcc tacgatcagg cgaaaaagca ctctaagcac aaagaggagt ttggaaacgg
    26221 ctctcttgag ggacttgcct cctgcgaggc tggaaacaac gcggtaaccg gcggctccat
    26281 gattccgctg atgacgctgt ccattcctgg aagccccaat gcggctatca ttctgggagg
    26341 tctgctgatt cagggcttag ttccaggcgc gcgcctgttc acgacgcagg ctccgactac
    26401 ctattcgatt ctggtaggct ttgccctttc caatatcctg atggtattcg tgggacttgc
    26461 aatcgcccgc tatgtagtaa atgtaacgaa aattccaaat tctattctga tgccggtagt
    26521 agtgtccctg gccctgattg gatcctatgc gatcaacgcg tccatgtttg atgtgtttgt
    26581 agctattttc ttcggtttct taggatacct gatgaataag ctggatcttt cttcagcagc
    26641 attaatcctg ggactgattc tgggcggtac ggctgagagc ggcttaatgc tttctctggt
    26701 tatggctaag ggagatccgc tcggctacta catgggacgt ccgatctgcc tggtgctgat
    26761 ggcgctgatt ctgctttcag tggccggacc tgtcatttca aaactaaaag ggaaaaaaga
    26821 aaaagcttaa atattaatat atgaaaaaga gctgcgaatc aagagagact cgagattcgc
    26881 ggcctttttc actcttttgc acttcagaaa aaacagcttt ccgtctctga aaagctgtgt
    26941 tataatactc atatcaatga tcatctgtga ttcatttaac attcagggac tgctttcaaa
    27001 cgcagtccgt cttatgaaga ttctatcagg ccgtttcggc tgaaatccaa aaatccaagg
    27061 aacaccattg ctgtaacatg aaaatttgat tatactgaaa ggagaaggca tgagacaaca
    27121 gcctctgcag tggcatccgg cgtttcaggc tgtgatgcag attgagctgg ccgaatatca
    27181 ggactggctg aagtactctg cccttcctaa aaaagagaac gtctggttaa gcaggctgag
    27241 gccagggctt gacgtggaag aggacatagc gatgctggcc caggcatatc agggaaggga
    27301 tgaaaatccc ctgtacagcg cggtaatgga gctgattgta agagcgaata aaaagcagta
    27361 tgaggaggcg aagcatatgt gcaatgcatt aagagaactg tttgcagagg agatagagga
    27421 gggaaggcag aggggcaaag cagagggaaa gatagaagga aaaatagaag gcaaagagga
    27481 gggccattgc ctggctttca ttgaaattct caggcgcaag gtggagaatg gaaaatctct
    27541 ggaggaatcg gcagaggccc tggaggagag gccggaagat atcgagaagc tttaccgctt
    27601 gattgaaaac caggggcctg atgcagacgc agagctgatt tatcagctgt accgggctga
    27661 tgtgaaatct tcagagaaaa aagaaggaca gcgctgatag tttcccctgc cgccgccttt
    27721 gttctactgc cgcttcctgc cgcgtaaact ggcagtaaca gctttggttt gaggaaaagc
    27781 atgaaatttt ttaaattaaa acgaaggcat gtctgtctgc aggaaaacgc ccttttctgg
    27841 gtatttttag ctctcctttc gattggatgc atggcgaagc tctacgaacg agcgtctctg
    27901 gccccggctg cttcagagag cgtgtttgcc tcctcccagg cggcggaagg cagggactac
    27961 caggttaagg acaggaagct tccgatttac tgcgtacaga cagagaagcc ccaggtggcc
    28021 ctctcctttg acgcggcatg ggggaatgag gacaccagac agctgatgga aattttggcg
    28081 aagcacaatg taaaggtcac tttttttatg acaggcggct gggtggagaa gtacccggag
    28141 gatgtaaagt acatagccag ccagggccac gatctgggca atcacagcga gaatcacaaa
    28201 aatatgagcc agctgggaga ggcggagatc cgatcggaaa ttcaaacggt tcacgaccgc
    28261 gtgaaggagc tgacaggaca ggatatggcg ttatttcgcc cgccttacgg agattatgat
    28321 gataaagtag tagccgtggc cgatcggatg ggctactatc cgattcaatg ggatattgac
    28381 agtctggact ggaaggatta tggggctgat tcgattgtgg ataaggtggt caatcacaag
    28441 catctgggaa acggctccat tattctcatg cacaacggag cgaaatatac gccccaggct
    28501 ttggaagcag tgattacagg gcttcaggaa aagggatacg agctggttcc tatttctcag
    28561 ctgatctgta aggaacagtt ctccattgac catgaagggc gtcagattcc gtctcaaaag
    28621 gcagttcagt aaaaaacttt tcgacaaaaa aacgccgttt tttgtctgtt ttcaaaattc
    28681 cgcgttgggc agaaagccag gaaaatgggg ataaaataga agaaccagac agacgcagcc
    28741 tcgcgccccg tgtcgaaaat tgcgttataa tctcattgaa tggcagtttt taccagatta
    28801 taatctatag agaaacaaat caggaggagt atgaagcatg gcagaattaa atatcgcgat
    28861 tgcagatgat aacaggcaga ctttggagct gcttggcgaa atactggagg gagaaaagga
    28921 ttaccatgtc gtaggaaagg cagataatgg aaacgaagca tacaacatga ttatgaaaac
    28981 caggccagat gtcgttttaa tggatattgt catgccggga atggacggaa tttccgtgat
    29041 ggagaagatt aagagcaacg cggaaatgaa ggacagcacc tcttttatta tggttacagc
    29101 cgccggaagc gaaaacctga cggcggaggc ctttaagctg ggagccagct actacatcat
    29161 gaagccgttc acaagggaga ttatcctgga taagctccgc cgcctgactg gctacaaaaa
    29221 taaaaccacc atgctgtcgg gaagcagacg ggtaaagcct tatgtcaaca aagcggagta
    29281 catggagcag aacctggaga acgacgtgac gcagatgctt cacgaaatcg gaattccggc
    29341 ccacatcaag ggatatcagt atttaagaga cgccattatt atttcagtag gcgatcagga
    29401 gatgctgacc tccgtgacga agattctcta tcccaccatt gcgaaaaagc acgatacgac
    29461 tccaagccgt gtggagagag ccatccgcca cgcgatcgag gtggcctgga acagaggcga
    29521 gatggatacg atcaacgatt tatttggcta caccgtaagc accggaaagg gcaaaccaac
    29581 caattccgag tttattgccc tgattgccga taaaattcgt ctggactaca aacggatttc
    29641 ctaaaaatta taatactacc tttctaaatg cataaattta ttgtataata agcttataat
    29701 ctggacaaag gggggactta tttgacgatt tgtccggcaa tgtgatgcac gggaggtagc
    29761 agaatgaaaa aaattctttt tatagcttca gaagcggttc cttttattaa gacgggcggt
    29821 ctggcggacg tagtgggctc cctgccgaaa tgctttgata aggagtattt tgacgtgagg
    29881 gttatgctcc ccaagtatct ctgcatcaag gaatccttcc gaaacgacat gaaatatctg
    29941 aatcatttct acatggatta tctgggacag agccgttatg tgggaattct tgagtacgtc
    30001 tatgagggaa tcacctttta cttcattgac aatgagagct atttctgcgg ttccaagccc
    30061 tatggagact ggtactgcga cctggagaag tttgccttct tctctcgggc ggcgctttcc
    30121 agccttcctg tcatcggctt tcagccggat gtggttcact gccacgactg gcagaccggt
    30181 ctgattcccg tattcttaaa ggataaattc cacgagggag aattcttccg gaacatgaag
    30241 tctgtgatga ccatccacaa cctgaaattc cagggtgtct gggatgtgaa gacaattcag
    30301 cgcctttccg gacttccgga ctactacttc acccctgaca agctggaagc gtacaaggac
    30361 ggaaacatgt taaagggcgg gcttgtgtat gctgacgcca ttactacggt gagcagtacc
    30421 tatgccgagg agattaagac acctttctat ggagagggac tggatggcct gatgcgggca
    30481 agggcaggca gcctgagggg aattgtcaac ggaatcgact acggcgattt caaccctgag
    30541 acggatccgc tgattgttca gaactacagt gcgcgaacct tccgcaagga aaaagtaaag
    30601 aataagagag cccttcagca gcagctggga ctggaacagg atgataagaa atttatgatt
    30661 ggaatcgtgt cgcgtctgac ggatcagaag ggctttgacc tgatccagtg cgtgatggac
    30721 gagatctgca cggacgacgt acagctggta gttctgggaa ccggggatga gaagtatgaa
    30781 aacatgttcc gccactacga ctggaagtac aatggacggg tttccgccaa tatctactac
    30841 tccgaggaaa tgtcccataa ggtttatgcg gcctgcgacg cctttttgat gccttccctc
    30901 tttgagcctt gcggcctgag ccagctgatg gctctgcgct acggcacggt gccgattgtc
    30961 agagagacag gcggcctgaa ggatacggta tggccttaca acgagtacga gggtacggga
    31021 actggttttt cctttgccaa ttataatgcc cacgaaatgt tagacaccat ccgttatgca
    31081 aagcatgtat tctacaacag aaaacgggag tggaacaaga tcattgaccg ggcgatggcg
    31141 gccgacttct cctgggacag ctccgcgctt aaatatcagg agctttacga ctggctgatt
    31201 ggatattagg gatgggcaga tgagatacag gagagaagaa tgactatcta tcaggaaata
    31261 acgggaaatc aggtattgat gagcggcgtc atcggctggg tggtggcgca ggtattaaag
    31321 accatcattg atattgccct gaacaagtcc tttaatccag aacggctgac cggatcggga
    31381 gggatgccca gctcccattc ctccactgtc tgcgccctga ccacagcctc agccttctgc
    31441 tatggctttg gaagctttga gtttgccatc agctttctct ttgccatggt agtgatgtac
    31501 gatgccatcg gagtccgcca ggagacaggc aaacaggcga aggttctgaa ccatcttctg
    31561 tttgagaatc ccctgaagct ggataccgtg gtgctgcagg agcggcttaa agagtatgtg
    31621 ggacatactc cgctgcaggt atttgccggc gcggtgctgg gaatcggaat cgccgtgttt
    31681 atgaatggat tttattagga caggagcgtt tgcctgcaaa gaaaagcgcg cgtttaagca
    31741 tgtctctaca cagcagagtg atagggacat gcttttttta tgcactgagc gtttctttca
    31801 gacatgcggc atcggataga atcaggccgc tccatcttga tgtgaagctg ttcgtctgca
    31861 aaatcaatgg ctgagagaat tgcggtgtag gagtcgcgct tgcagcagcg ggggcctcca
    31921 atctgcccga tggaggagag gctcctggcc gtcatctggt tggccagccc ccaggaagct
    31981 cctgttaagg gggtggcccc tgtggcgatg ctcataaaga tgcctgtgct gacgcctgcg
    32041 ccgcaggtgc cccactggcc gcagataccg ccgggaacct gagaaccccg ctccttcatc
    32101 tgatccaggg cagaggataa atccagttca ccgccgcagt ttttgtaggc ggccagaaga
    32161 gccgcgccta ccaggacgtg gtgttccggt ccgtgcatgt ggatctgggg aaagtcaatc
    32221 agctgctcca taatagcgac aggatttttc agctctgtgt ggagacagaa ctgacagatc
    32281 agatccagag cgtcctttgc atgacaggaa tcgcagatgt agtggccgtt tgcacagcgg
    32341 gcatgagagg agaaagagcc accgcagacg gcgcatttca tggtttcctg gtgttccaga
    32401 taaatcaagg gagcgccgca gatcaggcat tcccaggggg tatttgacgt actcatagaa
    32461 aaacctcgtt tctgatagtt taagataata gctggatgct ttaaaagata atgttattct
    32521 gaaggaagac aggaataatg tcaagaaaaa tgtcaggaaa aatgcaaaga gaactgccgg
    32581 cgcaactggg cacaggcgat gacatgccgc atgaaaaaag gaaggaaaga gcagggccgc
    32641 ttctgtctgg acgccgccga aacctgcgct tttcttcctt tttgaatgcc tatggccagg
    32701 cttttataaa aggttcataa atgtggttaa aaccatggag ttgaagaagt cgataaagag
    32761 acttccaact aacggtacga tgaagaatgc ccttggagct gctccgtagc gctcagccag
    32821 agctttcatg ttagccatgg cgttaggggt tgcgcccatt ccgaaaccgc agaaggcgct
    32881 tgtcatggcc gccgcctcgt agtcccgtcc catcacgttg aaaattacga agtttgcata
    32941 taaaaacata atgacagtct gaaccagaag gatgacaatc attggaagag ccagggctgc
    33001 cagctgccag agctttaagt tcatcatggc catggccagg tagatgttca gagaaagtcc
    33061 acccagcgtg tcgatttctt ccatcggaag gtcagctccc tttgcatccc agatatttct
    33121 taaaagagct gcaaacagca tggctccgat gtagcctggc atggtgatgt tgagcttgga
    33181 gaaaccagtc atgattaagg ttccagctcc aatcgctatg gccaggaata cagctgcatt
    33241 agtaaatttc tggctgtcaa tgattccgcc tttgtcattc gatgcgttgc cttcctgtgc
    33301 cgctgtggat tttaatccca gcttttccac tctacggcgg gcaatcggtc ctcccatcat
    33361 gcttccggaa accagtccgt atgtagctgc tgccagagcg acagtcaaag ctccggaaac
    33421 gccgtaggtt tcctcaagga gagggccgaa ggagccggag gttccgtgtc cgccgactaa
    33481 cggaatcgaa cccatgcaga ggccgaggag cggatccagg ccaaaggccg ccgctaaagc
    33541 gcttcccacg ccgtcctgga ttacgcacat gaggacagac agaatcagga agataaatac
    33601 ctggattccg cctttcttca aaagccggaa gcaggcggta aatcctacgc tgcagaagaa
    33661 cacagtcatt agaatggtct gaaccgttgt gtcaaaggtg aattccagga ttcccgcgct
    33721 gtacagcccc agatgaagca gagcgaaaac aattccgccg gctacagggg ctggaataca
    33781 gtaacggttt aaaaaagaga tttttttcac catcagacgt cctaaggcgt atacgacggc
    33841 tcccagagcg caggcctggt acatgtcaag ctgcaatgtc atcataaaag attccccctt
    33901 tcagtttatg agcctattat gagacgcagc tacaaaaaac gacaaaaagg tgaattatct
    33961 gactgataag aaaacgttaa gataacttca gcataacaca ggctcagtaa ggaaccctag
    34021 tcggtctctt cggcgggttc tccgtagaga agctcgttgt catagaagtc agatttcata
    34081 ttcagctgtg agataacctc ctctttaccg aattcgtcga gaatcgtatc ccggtctgag
    34141 aacaggttgg ttcccagccc caggcggtct ccctcaatct ctacgcccat agcggccagg
    34201 gtggtaggga agagatccat ggtgcaggca gaatgggttc tgtctgcggg cacggccgcc
    34261 ggatttaaaa agcagtagta gacgccccgc tcgtaggaat cgtcgtcagg cgcgtaattt
    34321 ttcaccatag tggcgtggtc gcctgcaatg acaaccgtgg tattttcata ccagggctgt
    34381 tccttgatcc agctgacaaa ttccactgcc tggcggctgc cgcagcgaag cacattgctg
    34441 tactgatttt caaattcatc gccgcagaga cggcatacat acccatctgg gttgtgggta
    34501 tccacagtga gaactgtgaa attaaagggc tggtttcctt cggagagctt tgtcagctcc
    34561 tccttggcgt actcaaagag cttttcgtcc tcaatgcccc accagccgat atcgtaatcc
    34621 ttgggaacct tcttttcccg tttcgccgtt ccaaaatccc agattttata attaccgtga
    34681 tccttaaaat actgatcccg tcctgcaaag ctggcatagg atccgaccat cagcatgttt
    34741 ttgtagccct cgtcctccag tacctctccc agggtgacgg cgccaggcag gaaggaacca
    34801 tacttgctca tggagttttt ctctaccgga atttttaagg gcagtcctga ggtctgggcc
    34861 accatagccg cgatagtcca ggaggaggtc agaggaagaa ttccctgttt tccatcagga
    34921 cccagctgga aggtgacgtt ttcatcggcc agagccgtca gctcaggaat cacattttcc
    34981 tccagatttc cgccgttttc tttatcctca aaggtctttt ccatcgattc cagataaata
    35041 tacaccaggt ttctcttctg ctccgggaag gtgagaatgg aagagtccgg cttctggtac
    35101 tgctcttcaa taaaggagct cttgtggaac tgattgtaga gatactctcc gatgtttaac
    35161 agattgtccg tgcctacagc cataaatacc aggccgaagg ccagcagcag agccatcgat
    35221 ttggagaagg cccggtcagt cagctccaca taccagcgtt tcttccccag acggacgtcc
    35281 acacaggtgt aggttttcct ggttctgaga aagaggcagc accggcggta gaggaacatg
    35341 gcggtaaaaa agacggccag agacggagcc agggccgtgc ccaggtagct gacgatgtac
    35401 tccgtattca cgccgtccag aggcacgttt aggtggaata cgatttcttc catgctgatg
    35461 cttccgtagg ttctcacagc ccaccaggcg gaaaaatagg ccagcagggt gacaaaaaac
    35521 aggagataca gactgatttt cctggcttta gctctcatgt tcgtccaccc tcttcttctg
    35581 ttccacggaa atgcttaaat taaaggaaac aattttggcc gttactgaca ggacgacagc
    35641 cgtaccgcag gcagtcagga gatagcgcac agaaaagata ttgtctgcga aatgtcctcc
    35701 tgaggccatg gagctgatgg gcatgaaaaa ggacgctatg gccagagccg ctccgtttac
    35761 cacagccgtg aaggcaaggt attttaagag cagattgacc agccattcca ggcttccctc
    35821 tctgcgcgtg tgctccccta caaaggctgc ccgccgaaac tccattctct cataaatcag
    35881 gagagccaga gcaggcggac agaacagata aataaatgaa aacactgtaa ttcctccgtt
    35941 ttgacataat ttacatggat ttgacataat acgacatgat tatagcggaa aagggcgggg
    36001 ttggcaatgg aaaaaaacag aggtttgaga ttcatatatt gatagtgatg agaaaatcat
    36061 tataagcata attctataat taaacatagt tatagattat acaaatggca caaaatatta
    36121 tcgttatatt gacaataatt ggataatgtg ctatagttaa tcaagtgaaa ggttaagcag
    36181 gttaattaat attatttgag acttgcttgc tggtttcatg caggatggaa cctaatttta
    36241 actgatagga tacagatgaa aggcagcatt ccatgaagac agaagcgtta atttatgaat
    36301 ttgatagaaa ggtgaaccgg tttcacacaa acagtgaaaa atatgatggg gcgtcaaagt
    36361 ttgctcccaa cgctccgaag gacaaaattc cattatggat agcagatatg gattttcaga
    36421 cagctccgga aattatagag gctatgcaaa aaagagtgga ggaagggatt tttggctata
    36481 cgaatatcta tgattcctcc tattatgagg cagtaggcgg ctggatggag aagcgccatg
    36541 gctggaaggt aaagcaggag gagatcgtgc tggattcagg agtggttccg gcagtgcttc
    36601 atgcccttag cctgatggct cagccaggag acggggtgat tcttcatact ccgtcgtata
    36661 caccatttta caattctatc agaacccagg gcatgagaac agtattttcg ccgcttcttt
    36721 taaaaaatgg acggtatgaa atcgatttag aggatctgga gaaaaaagcg tccgatccag
    36781 agaataaggt attaattttc tgcagtcctc ataatccctc cggaagagta tggactaggg
    36841 aggaactgac agctgtgatg gagatttgcc ggaaacacca cgtgtcagtg atcagtgatg
    36901 agattcatgg ggatctgctc agggcaggaa gaacacatct ttccctggta ggattattcc
    36961 cagaagagaa acgtctgatt gtatgtacct cccccagcaa gacgtttaat ctggcaggaa
    37021 atcatttggc caatattata attccagaca gagaaatcag ggaggagtgg gagaaacgat
    37081 accattacat gcctaatcct atttcagtgg cagcgacagt ggcagcctat accagagcgg
    37141 aaggatgggc agacgcttta aaccagtacc tggacggaac gtttcagatg atggagcagt
    37201 atataaagtc tcatatgaca ggcgtttcct ttacagtgcc tgaaggaaca tatctggctt
    37261 ggattgatat gagaaattgc ggtctggcac ataaagagat ggtaaacaga tttttgaaaa
    37321 acggacttct gattgaaggc ggagagcagt ttgtggcaga tggagaggga tttgtacgca
    37381 tgaatattgc agctccacga tgtgtgatac aggaagctct ggaacggatg agtacgctgt
    37441 tttagagaaa gaggaagatc ccaaatcata ttttaatata aagataaagg aggaataagg
    37501 gacatgaaaa agaaaggttt agttctggct gcagtgctga tggtggctgc agcgctggct
    37561 ggatgcggtt cccaggaaaa agcagaggag acaaaggaga cagctcaggc agctgaaagc
    37621 gctgggggag aagagacgac agcagagaaa gagacggctg aagaagaaaa agcggcggag
    37681 ggatccggaa gatatcagag tatcctggat gcaggtgttc tgaaggtagg cactgagggc
    37741 acgtataaac cttttaccta ccatgacgag agcgacacgc tctgcggtta tgatgtagaa
    37801 gtagctaaaa tgattggcga taagatgggg gtagagacag agtattctga gattacctgg
    37861 gagggacttt tgacctctct tgacacagga actgtagatc tggtgctgaa tcaggtaggc
    37921 gtaactcctg agagacagga aaaatacgat ttcagcgatc cgtatctgta cagctatatc
    37981 gccctgatta cgctggagga taatgaggag atcacagact gggagagcgc agagggaaag
    38041 aaaacttcct taaatgtatc cagcaactat gcaggaattg cagagcagta cggcatggaa
    38101 atcacagctt ccgatacctt cagcaaggat attgagcttc tgctggcagg aagaacggac
    38161 tgcgtaatca ataacaccat tgcttttaat gattacctgg ctcagaagcc agatactccg
    38221 attaagattg tggcagttca ggagactccg gatacagtag ctattccgat tccaaaggga
    38281 aatgaggatc ttgtggaggc tgtgaacaag gcgattgcag agctttccga ggagggaacg
    38341 ctgacagagc tttctgagaa atatcttgga aaggattttt ccagggagat gactttggaa
    38401 gaactgactg aaaaataagg acagaacaaa aggaggataa atggaatgga tgcacgtgcg
    38461 attgaaatat tgacagaatc tttttggcct atcctgaagg caggaatttc ctacacaata
    38521 ccgctgacat tgattgcatt tgtcctcgga actcttctgg cagtggcggt ggcagtgatc
    38581 cgtgtttcca gagtaccagt gttaaacaag ctgtgtgagc tgtatgtgtg gattatcagg
    38641 ggaacacctc tgctggtgca gttgtttctg gtattttttg gccttcccaa ggtgggaatt
    38701 gtgattgagc ctatgccggc aggtattgtg gtattttctt taagtattgg cgcttacagt
    38761 tctgaaattt tcagggccgc gattctctcc ataccaaaag gacagtggga ggcggctatg
    38821 tctctgggga tgagttatcc tcagcagctg gtccgcatta tcctgcccca agcagtaaag
    38881 atttcagtcc cgcctttgtt taacagtttc attgccttgg taaaggatac gtctctggca
    38941 gcgaatatta caattccaga gatgtttctc acgacacagc gtattacagc ccgcaactat
    39001 gagccgctgc tgatgtacat agaggtaggc tttatttacc tgattttctg tactgtactc
    39061 aattatcttc agaagaaggt ggaggacagg ctgatgctga cgccgcatga gaaaaagaaa
    39121 attaaggaaa ttacagacag ccaggggtag gaggagctta tgctggaaat cagacattta
    39181 aataagtatt ttggggataa ccacgtactg aaggatatta atctggaaat tgaatcaaag
    39241 aagacaacgg caattatcgg ttcctccggt tctggcaaat cgacgctgct acggtgcatg
    39301 aatctgttag agacgccgga ttcaggggag atcagcctgg atgggaacac gcttcgcttt
    39361 ccgggaaagc tttctcggaa agaaaaggcg gcgtttacca agcggacagg tatggtattc
    39421 cagggattca atttgttccc tcatatgaac gctctggaaa atattacaga aggccctgtt
    39481 acagtgttga agcgcgataa aaaggaagcg cgggaggagg ctatggcgct tctgaagaag
    39541 gtaggacttg aggataaatg gaacagtctt ccaagtcagc tttctggagg acagcagcag
    39601 agggtggcta ttgccagagc tcttgccatg aagccggaga ttctgctgtt tgacgagccg
    39661 accagcgcgt tggatccgga gctgggagct ggaattctaa gcctgatccg tgatttgtct
    39721 caggaggact acaccattct ggtagttacc cacaatatgt cttttgccag agaagtcagc
    39781 gagcaggtag tttttgtgga aaagggaact attttagcta aaggaagtta tgaagagctg
    39841 acttctatga ataatgaacg cattactcag tttttaagtt atctggatta accagatgaa
    39901 agtaaggagg ggaagatgga acagacagaa aaaatactgg ttctgggttc tctgattatg
    39961 gatttgtcgg ttcgatgcag acaggctccg agagaggggg agacggttta tacagacgac
    40021 gattatcaag ccaatccagg cggcaagggg gggaatcagg cagtggctgc cgcccgggca
    40081 ggggcagagg tagttctttt aggcaggata gccgatgacg attatggccg tgccttaaag
    40141 gagagttttc atagagatag gatagatacg agccgtctga ttacagattc ttcagccaaa
    40201 acgggaactg cgtttgtctg ggtagaggaa aatggaggaa accgctgtct ctgttctctg
    40261 ggagtaaatg gaagaaaccg tccggaggat tttatacagt atgaatctct atttcaagag
    40321 agccagattg tgctgactac gttagagtat tcgaaagaag tactggatca ggtgaccaaa
    40381 atggcaaaac aatcgggatg ccttcttata gttgatccat cagctaatga ttattccaaa
    40441 cttacgcctg agatagcgga gagaattgat attttaaagc ccaatgaggt agagacggag
    40501 atgctgacag ggattgcggt actctctcct gaggacgctg caaaggcggt aaagcggctg
    40561 aaagagatgg gaataaaaac accgattgtc tctatgggaa gtcagggagt agtttatgac
    40621 tatcagggac agatcattca tgaaccgggg attgaaatcc aggcagtaga cacgaccgct
    40681 gcaggagaca cctttatagg aagtctggct gcccggctgt ctttgggaaa agaatttcca
    40741 gaagcagtaa ggtatgcaaa ccgagccgcc agcctatgtg tgcagaagaa aggagctcaa
    40801 agctctatcc cttttatgga ggatgtatta taataaaggc ggcgggggtg aaaaaacagc
    40861 tctgccgcct ttggcatgga tgggaagcat ttcgtccggg cggaggtaga ataagaataa
    40921 agggcggaat gcagaatgga caaaaacaga tatttaatct attgcgatat aatgaaagag
    40981 ttaaaggaaa cgtatgagct gatgcgggag tatgacggct tgccgcacga ctacggcaac
    41041 gtagtgctgt atcagtcgga ggcgcatttg attcagtgca ttggacagca taccggcatt
    41101 actgtgacag aggcatccaa gattctaaaa aagacaaaaa gcgcctgctc tcagatggtc
    41161 aaaaaactag tgggaaaaaa ctgggtccgg caggagagaa ataagcagaa taacagagaa
    41221 tataagctgt atcttacaga agaagggctg gttatctatg atcaccatga aaatttcgac
    41281 cgtctgtcat atgaacataa ctcccaagaa ctgtttgatt ttacagatga ggagctgaaa
    41341 aaatatattc agattcagca gaagatgaat gaactgatta aacttgacgt agagagaagc
    41401 tataattatt ttactacaac tcctcaggaa ttaatggaga aatgagatga aacgagaact
    41461 gaaaaatgta tttgcaactg aaaaacccat tataggaatg gtacatctgc ggcctctgcc
    41521 gggatctcct ggttacgatc cggtttctat gggaatggac aaaattttag agaacgctgt
    41581 ggaagaggcg aagaaactgg aggcagcagg agtggatggc gtgcaggtgg aaaatatgtg
    41641 ggatatccct tacctgcggc ctgaagatat gggatatgag acggcagcag ctttagcagt
    41701 aggcgtctac gaggtgagaa agcaggtttc aattccagtt ggggcagaat gccatatgaa
    41761 tggggcagac tgtgccatgg cctgcgctgc cgcggctgga gcagactgga ttcgtgtctt
    41821 cgaatggtgc aattccttta tttctcagtc gggctttatt gatgctatgg gagccaaggt
    41881 ggccagaatg aggaaaaatc tgggagcaga tcatatcctg gctttgtgcg atgtaaatgt
    41941 aaagcatggc agccatttta ttatccatga cagaagcgta gaggagcagg ctatggatgt
    42001 ggaggcgcag gatggagatg cagtgattgt gactggcttt gacacaggaa caccgcctac
    42061 agtagaaaat atcttaaagt gcaaggagtc tgtcagcctt ccgattttaa ttggaagcgg
    42121 cttgaacagc aataatgtcc acaagctttt agctgcagct gacggagcga ttatcggaag
    42181 ctggtttaag gaagacaaca attggaagaa tccagtcagc tttaaacgag ctaaggaatt
    42241 tatggatcga gtgaaagcgc ttagaaggca atagggaaaa tagcataaaa tattttggca
    42301 gtacctgaaa tctgtgctag aatggtacaa tcacatattc aggaggtgct gcgatgaaat
    42361 atacggggat agaactgctg tggctgtttc tgctctattc atttttaggc tggacgctgg
    42421 agacagcggc gggaaccata cggcagaaac gttttgtaaa cagaggattt accacgggtc
    42481 cgttctgtat ggtctacggt gtggcagcag tggtgatgac tgcagccctt caggaactta
    42541 gaggaagctt tcttttcctg tttctgggct gtatggtagt cggaacggct gtcgagtggt
    42601 ttgcaggcaa gcttctggaa cgtctgaatc agaaaaagtg gtgggactat tcagaaaaaa
    42661 ggtggaactt tgacggatac atctgcgccc agtattcact gctctggggc attttgggaa
    42721 ctgtcaccgt ccggtggggg gacggtcttc tggtgggact gtgccgcctg ctgccatcct
    42781 ttgtctccag tctgctgacg ctgggagcgg caggcatgct ttttctcgat atggcagctt
    42841 cagcagctac tgtctggcat gtgaaacgcc gtgtaaagca gaaggatgca gaaaagcttc
    42901 agcagctgaa cagccgtctg gcgtcagcga ctgcccgcct gggaagcagg attgaggcga
    42961 gagtggcccg gcgtatggaa aaggcctatc ccttgatcct ggaggtttct gagcagattg
    43021 caaggcagaa ggtatttgcc ggcggatgcg gcttttataa gctcttctgg cttttcttaa
    43081 tcggagcctt tttaggcgat attgtggaaa ctattttctg ccgcctgaca gccggtgtgt
    43141 ggatgagccg cagcagtctt gtgtggggcc ctttcagcat tgtatgggga cttgccatag
    43201 cggcggccac agctcttctc tataaagaca gagagaagcc ggaccgccac ctgtttgtca
    43261 tcggaactgt gctgggagga gcctacgaat atatctgcag tgtctttaca gagctggtat
    43321 ttggcaaggt gttctgggat tacagtaaaa ttccctttaa tctgggggga agaatcaacc
    43381 tcctttactg tttcttctgg ggaattgcag ctgtgatctg gattaaaaat ctctatcctc
    43441 tgttttctgg ctggattgag aaaattccag tgctgtgggg ctatgcgata acctggatgc
    43501 tggttgcgtt tatggcagtg aatatcgctg tctcttctat ggcgctggtt cgatatgaca
    43561 ggagagcgga gggaaggcct cccagaaatg ctgtggaaca gctgatagac gaacggttta
    43621 acgatacgag aatggagaaa atttatccta acgcgctgtc ccgctagagg aaggccgcag
    43681 gggaggaacg gatgaaaagg gaggaaagaa cccgcacaga ggcatgaaaa gtcccatata
    43741 ctgaagtaac aggaaatgaa gggggacaat gctatgaact ccaagctgga ggttcagggg
    43801 ctttcctatt cctatcactc catggacgga gagacgaagg ctctttccaa tatatccttt
    43861 caggtggagg agggagaatt tctggctgtc gtaggcccgt caggctgtgg aaaatctacg
    43921 cttctttcca ttttgtgcgg acttcttgtg ccggaggagg gaagcgtgct tatagatgga
    43981 gagccggtga agggaggcag tcccaaaatc ggctatatgc ttcagagaga tcacctgttt
    44041 gagtggaggg acgttttttc caatgcctgt ctggggctgg aaatacgcgg gcagatggac
    44101 agagaacaca gagaaaaagc agagagactg tttaaaacat acggtctgct tccatttaaa
    44161 aataaaaagc cgtcagagct gtcgggagga atgcgccaga gagcggcact tatacggacg
    44221 ctggctttgg atcctgatat tctgctgctt gacgaaccct tttcagctct cgactatcag
    44281 accaggctgg cagtgtgcga cgatatcagc tctattatca gggaaaacag aaagacagcg
    44341 gtgttagtta cgcatgatct ggcagaagca gtgagcgcgg cggacagggt tctgattctc
    44401 accagaagac cggggagaat caaaacggtt cttcccatta cattcgcaga gccgtctctc
    44461 agcccgctgg agagaagaag cgcaccggaa ttttcaggat attttaatca ggtgtggaaa
    44521 actcttgaaa acagggaggt gtcccatgaa taaccgtgaa acgctggccc agcggacttt
    44581 tgtcgcaggg cagagacgct acaggagaag gattgcagca ggacgcatcc ttctcttttt
    44641 cgcttttctg gcagtgtggg aagcgggcgc agatacagga cttttggacg attttatttt
    44701 cagctccccc tccagggcgc tgcggtgttt ttttgtcatg gccagtgacg gcagtgtgtt
    44761 cccgcatctg ggtgcgacgc ttttagagac ggtggtgagc ttcttcctgg tgacggctct
    44821 tgggcttggc ggggcgctgg ccctgtggga aagccggact gcttccgatt tgctggagcc
    44881 ctatctggtt atgctgaaca gtcttccaaa gtctgccttg gctccgcttt taatagtctg
    44941 gctgggaagc aatatgagaa ccattgtgac agccgctgtg tcggtagctg tcttcgggtc
    45001 ggttctgacg ctctatcagg gctttctttc catggatccg gatcaggaga agctgattta
    45061 ttccctgggg ggaacgagga gggatgtact gagaaaggcg cttctgcctg gttccatccc
    45121 tttgattgtc agcaacatga aggtaaacgc aggactctgc ctggtaggag tcatgatcgg
    45181 agaatttctg gccgccgaca aggggctggg ctatctgatc atctacggaa gccaggtatt
    45241 taaaatggat ctggttatca tgagcattgt gattctctgc ctgatggcgg cgcttctcta
    45301 tcagggaatc gcttttctgg agaaaaaggt ttccagaagg ttgtagttgt gcgggtatga
    45361 taaaccatgt ataatagcag cagataatga gtgaaataaa ggctgataag gcgcaggagg
    45421 actctttatg attcaaacag atacaggaaa caaaacgacg ctgagaaact acgaaattgc
    45481 cctgattcag atggataccc agaatgacaa gggggaaaat atgaaaaaag cctgtcgctt
    45541 tatagatgag gcagcaggcc acggagcgaa gctcatctgt tttccggagg tgatgaatct
    45601 cattggcaga aatataggag aaggcggagg aaaggaagaa attcccggtt atacctcaga
    45661 tattctctgc aggaaagcca gagagcataa ggtatggatt cacggaggaa gcataacaga
    45721 gcaggtgccg ggtcagaaaa aatccagaaa cttaagtctt ctcattaatc cggacggaga
    45781 gatagccgcc cagtacagaa agcttcacat gtttgacatt acgctggcag atgggacacc
    45841 gtttagggaa tccgaccgtg tggaaggggg aaatgagatt acaaccgtct ccacagagct
    45901 tggaaccttc ggtatgtcaa tctgctacga tatccgcttc ccggagttat accgcctgat
    45961 ggctcttcag ggggcccagg taatgttcgt accggccagc tttaccatgc ctacgggaaa
    46021 ggatcactgg gagccgcttc tgcgggccag agcgatagag aatggctgct atattgtggc
    46081 ggcaggtcag attggcacaa aaccggctta cgcggcttat ggaaacagca tggtagtaga
    46141 cccctgggga acgattatag ccagggccag agatacggag tgtatcactt acgcccagat
    46201 cgacctggat tatctggatc agatacggga acagctgccg tctctggaga accggagaac
    46261 cgatgtgtat gaggtaatca gtaaaaaaga aaaataagga aatgagagat atgcagtctg
    46321 gaagaacatc agaaaaggtg ttttccaggc tgtatttttt atgtcatgag aagctgcatc
    46381 tcgtgaaaat ctctatagat agaatctata tacaaactat aatatagaaa ataaacatat
    46441 tgtcggaaaa ataacgaaaa aatattgaat ataaaattaa tatctgatat gatgcccatg
    46501 tatgccagca gtaattcggc agtatccata aaaattttag caaattagag gaaaggttgg
    46561 aaatggaaaa gcagctgata aaacggttca gtaaggctct gggactttcc aggcaggtag
    46621 tcggaatcaa atttattttc ctgaaagagg agtatgagga tctggatgtg cctgagccaa
    46681 aagcaggcgg atgcttctgt gcgctgactg ccagagcaat ggaaggaaag attatgaagg
    46741 gaaaggctga caccttcgga tgtcagggag gcccggaaat gctgggcatg aaaaaggttt
    46801 ccaattatgt gtggtcaggg aaacagtttt ctactttaag attgtatgaa gacgcggcca
    46861 ttgccagaca ggtgcagcag gatctctgct ttgtagatca gaggatttac ggtgtcatga
    46921 caggtcctct ggaggagatg gaggatgcag atgtggttat gctgttatgc aatggctggc
    46981 agatgatgcg cctgatacag ggctacacat ggcatcacgg tatggcaaag aatattggca
    47041 tgattggaaa tcagggaatc tgtgccgatc tggtagccag accgtacatg aaaaatgatc
    47101 tgaatgtgtc catgctgtgt ctgggagcca gaaccaatac gagcgcagag gatggagaaa
    47161 tcggagcagg tatgccggtt cacctgttta gagatgtggc agagggcgtc ttaaaaaccg
    47221 tgaatcctgc tatgtcagat aaagagaagc aggcgctgtc tgagcgtctg gaaacgccgg
    47281 atgagctggg atttgaaata gaattcggaa aggtgtatat gagctacgcc aaggaaaaaa
    47341 agtatccgga ggaattgtat aagcagtcag gcaatgacta gaactttgtg gaaatccggg
    47401 cagcttataa agatatgtat aaataaaaca aataaaacaa aaaaacataa aaaacaaaac
    47461 aaaataaata aaatcaacga aaggaaaaga gaaatgaaaa agaaatttgc acgtattctg
    47521 gccgcagggc tggctgcctg catgatgaca ggctgcagca ttggacagaa gacagacaca
    47581 ccagcagaga cttcaaaggg agcgtcacag gcagaaacca caggaggaca ggagacagaa
    47641 ggggagaaaa aggatacagt tgtgtatggt acaccaacag ctcctgtagg aacctttttc
    47701 ccgattcttt cctatatggg aagcgatata gctcttgaaa aattaatcta tgcgtctctt
    47761 tttacgtttg attcagaagg aagcttaaag ccgtatctgg cagagagcta cactgtttct
    47821 gaggatcaga aaaccattga ttttaaaatc cgccagggtg tgaaatggca ggatggtgaa
    47881 gatttcacca tggatgatct gatttttaca atcgaatcgg ctgctaagag cgtagaggat
    47941 tttgagaaag ttgcttatgt taagggagca gcagagtata aggatggaca ggcagattcc
    48001 atcagcggtg taagcgttcc agaagaaaat gtgctgagat tagagctgac agagccttac
    48061 gcaccattta tggctgattt tggaacttat ggaattattc caaaacatgt ctggagtgag
    48121 attccacagg aggagtggga gaagcagaca gaactattaa accagccggt aggctgcggc
    48181 ccatacaagg tgacaaagtt tgagccggga cagtatgttt ccctggaagc ttatgaggat
    48241 ttctttgagg gggctcccaa gattgacaac tttattttaa aggtagtaaa ccaggacgcc
    48301 atctcagcag agctggtcag cggaaatatt gatattgtgg atgtaaagga aatgagaagc
    48361 agcgagatag aggagctgga agcacagggc tttgccaaat attcaattcc ggatcatatg
    48421 taccagtaca tttcctttaa cctgcgccgc ccggaattcc aggataagaa tttaagacag
    48481 gctatgctgt acgccattga ccgtgctctg attctggata ccatcgtaga gggaagagga
    48541 aagcttctgg attccccgtt cctgccaggt tcctgggcaa gtccggcaga aggagagtta
    48601 aacaagtacg cttataatcc ggaaaaagcc aaagagcttc tggaggcgtc cggctggaca
    48661 gatgcagacg gagacggagt gagagagaat ggagatggag agaagcttca gtttaccatc
    48721 cgctgctcca atgactctaa aacaagagaa aatgcagtgc tctatgcaaa agagtgtctg
    48781 gctgaggtgg gaatcgatgt ggaggtttcc attgaggagg acagcgtaat cgctgaggac
    48841 tgtatttata atcataattt tgagatgtac gctttaaact gctatttctt tgaagatccg
    48901 aatccatatg gctggtggca ttccgattcc gcttttgatg agccgggagt gggaagcttt
    48961 aactttggcg cttataaaaa tgatctggta gatgaaaaca tcgaaaaggg tatgaagact
    49021 actaatcagg aagagcgaaa agagtactac ctgaatgtgg caaagcagat caatgaagat
    49081 gtaccgatga ttttcctcta tgcccaggat cgcgagatca tgtgcaaccc gaagctggag
    49141 aactttgatc catatacatt taatattttc tgtgatattt gggaatggga ttttgcccag
    49201 taaggaggta gaattaccga aatggcacgg tttatctcaa gaaggctggc agctgccttg
    49261 attatgcttc tgggcgttac ggcggtgatt ttctgtatca tccgtctcca gccgggaaac
    49321 ccgtttttaa atatgattca gcatgataca gatccgacct ttctggagac aaaacttcag
    49381 gaaatcggct actatgaccc gcttcccgtc cagtacggga agtggctttt aaggacgctc
    49441 cagttcgatc tgggatactc tatccagcac aggactcctg tggctgcatt gatagcagac
    49501 aggtttggaa atactctgct tttagccatg tcctcctttg tgttaagtac agtgatttcc
    49561 attggaatcg gagtattttc agccatgtat cccaattccc tgtgggatcg ggcactgact
    49621 gtcttatcgt ttatcggcgt ttccatcccg gtatttttct ttggacttct gctgattaag
    49681 gtatttggat acgatttagc agtccttccc ttttcaggga ttgaaaccat ggggaaaaat
    49741 taccagggca tagacagggc gctggacatc gggcgtcaca tgattctgcc ggtgactgcc
    49801 tcggctctta cccagacagc caccctgctt cggtataccc gatcctccat tctgtccact
    49861 gtatcggagg attacatgaa aacagctcag gccaaggggc tcacgaaaaa gcaggcgatt
    49921 ttaagacatg gaatgagaaa tgccagagtg tctattatca cggtgctctg caaccgcctt
    49981 ccagacctgt taagcggagc gctgattgtg gagacgattt ttgtgtggcc tggaattggt
    50041 cagctgaatt atcaggcaat tttagtcagg gattatccgc tgattatggg aattgccctt
    50101 ctgctggcag tgattgtaat cgggtgcaat cttctggcag acgtactctg tatgatactg
    50161 gatccaagag tgagaaattc tgtcggcgtg taatacgcag gcagcagaaa cgatgagaaa
    50221 cacagacagg aaaagacatg aaaaaaaggg aagaagaaaa gattttgacg gcgggacaga
    50281 ttgcccgccg gcgttttttc aggaacaggc tggcaacagc cggactgatt attgtagtat
    50341 cttttgtatt tttgtctctg tttgcccctc tttttacaga ttacacagta agccagacgg
    50401 atttaagaaa tctccggtca gggccgtctg ctgctcatct tctggggaca gacgatctgg
    50461 gacgtgatat ttttgccagg ctgctctatg gaggaagggt ttccattgcg gtaggcgtgg
    50521 cttccatgct tcttcagatg gcaattggcg ttaccctggg agcggcggcc ggctattttg
    50581 gcggggtgac agacaaggtg attatgcgga tggtagatat tattatgtgc tttccgtttt
    50641 ttgtcatagc agtggctctg gccgctgtga ttggcggaag tatctggaat ctgattctga
    50701 ttataggaat gctgatgtgg ccgggaattg ccagaattgt caggacggag gtgcttacca
    50761 tccgtgacaa tgagtatatt atggcggcaa aggctcttgg actttctcct gtgcagatta
    50821 ttgtgaagga ggtactcccc aatgtatttt cttctatttt agtagcatct actctggcag
    50881 tggctaatgg gattttaatg gaatccacac tgagctttct gggactcgga gtgcgtcctc
    50941 cggctcccag ctggggcaat atgctggtgg cagctcagaa tatggcggtg ctgaaaaatc
    51001 agtggtggat gtggattccg gcaggagcag cagtagtttt gatggtactg gccattaact
    51061 ttctcggcga tggactgaga gatgccctgg acaccagaaa tcagcagtaa aggggaagag
    51121 accatggagg agatactgaa ggtaaaccat ctgaacgtag tgtttgatga tatatcaggc
    51181 cccctgacag ccgtttacga tgtgaatttc gggctgagac ggggagaaat actgggaatt
    51241 ataggagagt caggaagcgg aaagagcgtg acagccagat ccgtcatcca gctggcccag
    51301 gtaggaaaaa gaggaagcat ttccggagaa attttatttc agggaactga tctcttaaaa
    51361 ctgaaggaaa aagagatgtg ccggatccgg ggaagcagga ttaccatggt atttcaggag
    51421 cctatgacag cgctgaatcc ggctatgact gtggaggagc agctgtcaga ggtgctgaag
    51481 cttcattcgc caggagaacg cgaaaagcac agggagagaa tccttgaaac gcttcgccag
    51541 gtacagcttc cggagccgga gattctgatg aagaaatatc cctttgagct gagcggaggc
    51601 cttcgccaga gagtggtaat cgccatggcg gtgattggaa agccggatat tattattgca
    51661 gatgagccta cgacagcgct ggacgtgaca acccaggccg agatcctttc tgttctgaag
    51721 aagattgcag gggaaatggg gagcgcagtg attttaatta ctcacgatct gggagtggtg
    51781 gcagagattg cagaccgggt gcttgtgatg tatcgtggca tgggggtgga ggagtgcagg
    51841 accgccagcc tgttcgatga gccacttcat ccctactccc aggggctttt atcgtcccgt
    51901 ccctctaatt ttaatgggag atattcggcg attccaggaa ccgtgaagca gaactacggt
    51961 gtgtttaagg gatgtcccta cagtgacagg tgtccctatg cgttggagac gtgcagagag
    52021 aagattccgc cgtcactgtc atttggagga gagcacaggg cagcatgctg gaagctttgc
    52081 aaggagggca gcagtgagtg agattatatt gaaagcagaa catctgaaaa agcattatga
    52141 agagaggcag gggctgtttt ccagaaagaa aagaataaat gctgcgctgg atgatgtttc
    52201 cctggaaatc aggaagggaa gcattatggg gctggctggt gagtcaggtt ccggaaaatc
    52261 cacagcagga aagaccatgc tgaacctgat aaagccgtca ggaggcaggg taatatttga
    52321 aggaaagcag atatttgatg cagacaaggg ggaatatctg gactccggtt ccatgacagc
    52381 cctcaggcag aaaatgcaga tcatttttca ggatccttcc tccagcctga atcctaaaaa
    52441 aaatgtggaa cagattatca gtgcaggtat tataaagcac agactttgtt ccggaagcca
    52501 ggtgagggaa cgatgtattg agataatgga aaaatgcggt ctggataaac ggcagatgat
    52561 gcggtatccc catgaatttt ccggcgggca gaagcagaga attggaattg cccgggcatt
    52621 ggcggtagaa cccagcttta ttgtctgtga tgagcctaca gctgcccttg acatgtccat
    52681 tcagtcccag attttaaatc tgatgctgga tttaaaggaa cagtatggtc tgacttattt
    52741 gtttatttct cataatctgg gggtagtaga gcatttctgc gatgagctgg cagtgatgta
    52801 caggggaaag attgtagaac aggggaaaac ggcagatctg ttttcttccc cagttcatcc
    52861 ctatacacag cttcttttat cttccgtgcc tgtttctcac cctgatgagc caaggcgtca
    52921 cacaggaggg cagccccagg atgagagtat tctaaagcat ggctgccgct tcgcgcccag
    52981 gtgtccttac agagagaaac gctgcacgga gcaggagccg cttctccttc catgtggaga
    53041 gggacatact gccgcctgct tccatgcagt gaaataaaga aaaaagtata ggacgttgga
    53101 cttgtcattt ggaaaaaagg cgatataata ggtctggcgg attatttgaa aaggcgcgtt
    53161 acagcgcctt tttccgtgca gtttttgata gaaaagagga cgaatcatgc agtcagaaca
    53221 acaatcttca acacttatga cagaggggag cataggaaag aaaatcatct ttttttcgat
    53281 ccctttgatt cttggaaatt tacttcagca gctgtacagc acggcagatt ctattattgt
    53341 aggaaacttt gtgggaagca atgctctggc ggcagtaggt tccagtacgg cccttattgg
    53401 ccttttgatt gcgttcagtc agggagtttc tgtgggggca ggcgtggtag cggctcagta
    53461 tctgggggcc aaaaacagaa gagatgttca gggttccatt catacagcct tcgccctggc
    53521 ggcagttctg ggaattattt taacagcagg aggaatcatc tgcagccgtc cgcttctggt
    53581 atggatgaat acgccggaag aggttttgga ggactcggtg atttatcttc agatttattt
    53641 tggcggcctg atttttaatg tcctttataa tatggcagct ggtattttaa atgcagccgg
    53701 caattccaag agatctctta tttacctggc ctatgcttcc gttaccaaca ttggcctgga
    53761 tcttcttctc atcggcgtgt ttaaaatggg agtggcaggc gctgccattg ctacagatgc
    53821 cagccagctg gtttcctgca ttctttccat gtggtatttg actcatgtgg atgcagatta
    53881 cagaatcagt ctgaaaaaga taggaatcga caaacgaatg gcagtgcgta ttgccaaaat
    53941 cggcctgccc accggcattc agaacatggt tatttccttt tccaatgtgc tggtccagtc
    54001 cagtgtaaac agctttggag cggcagccat ggccggattc ggggcctata tgaaaataga
    54061 cggctttaat attctgcctg tactcagctt cagcatggca gttactactt tcaccggaca
    54121 gaactacggg gcaggaaaaa tagagcgagt caaaaaagga atgtggatta cggttctgat
    54181 gggatgtgtc tataccattg tgacaggaac cctgctcctg acctttggtg atcctctgat
    54241 gcggcttttt acagacagca gagaggtgat cgagcatgga aaactggcca tgaaatattt
    54301 ctgcccgttt tattttcttt taagtattat gcacagcctg gccggaacca tcaggggagc
    54361 tggaaaaagt attcctccta tgctgatcct tctgtttgcc atgtgtctgt tccgcatttt
    54421 ctggattaaa gcgattcttc cggcattcgg gacactggac ggagtctata tgctgtatcc
    54481 tgtctcctgg gcagtgggaa tggttcttat ggtcctctat acctggaagg gaaagtggct
    54541 ggaggagcag taaaaacaat attatctctt gaacttcctg ataaaaggtg atatactagg
    54601 ttacgataac ataatagact gacagaaaaa gagtggacca aaaggcccac tctttcatcg
    54661 tataggaact tacttacgtg cgttcccata cgatgaaagc tttgcaggat gcgcactccg
    54721 cgcagaggaa aagggctgct gaagcagctg cgcgtcggcg caggagtctg cctatgcaga
    54781 ctctaaagga taggaacgca tttcagtcag tcgatggata tgcagaaagg cggtgttacg
    54841 atggcgagaa gagaagaata cgagtcaaag gtagaggcat ggctgcttcc gctgctggaa
    54901 aagaatcagt ttgagctggt ggacgtggaa tatgtccgcg aagccggaat ctggtacctg
    54961 agagcctaca ttgataagga aggcggaatc acggtggacg actgcgaggt ggtaagccgc
    55021 gagctgggag actggcttga ccagaaggac ttcatcgagg acagctatat tctggaggtc
    55081 agctcaccgg gactggggcg tcccttaaag aaggaaaagg actttgcccg cagcctggga
    55141 aaggatgtag aagtgaggct ttaccgccca atcaacaaac agaaggaatt tacaggaacc
    55201 ctgaaagcat acgatgcaga tacagtgacg ctttccatgg aagatggaaa cgacctggcg
    55261 cttgccaagt cagatatcgc gttaatacgt ctggcctttg atttttaaac gacaggagga
    55321 taaaaaaaga aaatgagtaa agagttgttc gaagcgttaa acgtgctcga aaaagaaaat
    55381 aatatcagca aggaagtgct ttttgaggcc attgagaatt ctctcctcac tgcctgcaag
    55441 aatcattttg gcagagcgga caatattaag gtatatattg acagagaaaa gtgcgacttc
    55501 gctgtttacg ccgagaagga ggttgtggag gtggtagagg atccgctgac acaggtaagc
    55561 cttgcggagg cgaagctttt agatccgaga cacgtatacg gcgatgtgat ccgggtgaac
    55621 attaactcta aggagttcgg ccgtatcgct acacagaacg cgaaaaacgt aattctccag
    55681 aagatccgcg aggaggagcg cacggctctg ttcgatcagt ggtactgcaa ggaaaaggac
    55741 gtagtaacgg gaattgttca gcgctatgtg ggtcatgacg tctacatcga cctgggcaag
    55801 attgacgcgg ttctcaagga gagcgagcag gtaaagggcg aggaattcaa gcctactgag
    55861 cacattaagc tctacatcct ggaagtgaag aacactaaga agggaccgag aatcaccgtt
    55921 tccagaactc atccggatct ggtaaagcgc ctgtttgagt ctgaggttgc cgaggtgaag
    55981 gacggaactg tggagatcaa ggccattgcc cgcgaggcag gctccagaac caagctggcc
    56041 gttgcctcca acgatccgaa cgtagatcca gtcggcgcat gcgtaggatt aaacggagcc
    56101 agagttaatt ccgttgtcag cgagttaaac ggcgagaaga tcgacattat caactgggac
    56161 gagaatccgg ccctcttgat tgagaacgct ttaagcccgg ctaaggttat cttcgtcgca
    56221 gcagacgagg aggccagaga ggcgcaggtt atcgtgccgg attaccagct ttccttagcc
    56281 atcggaaagg aaggccagaa cgccagactg gcagccagac tgaccggctt taagatcgat
    56341 attaagagcg agacacaggc cagagagtcc ggtctcttcg acgagatgga gattggatac
    56401 gagcagggct ttgaggaagg actgccagag ggcgtggaag ccgacgattt ctccgattat
    56461 gaggaattat cctctgattt ttctgcagaa tctgagacag aagaggaaaa ctaaaggttt
    56521 tttgaagcgg atatcagagg aaagaacagc cagattggga agtgagaaga attgggaatg
    56581 aagaagatcc ccttaagaca gtgcatcgga tgcggtgaaa tgaagagcaa gaaggaaatg
    56641 atccgggtgc ttaaaaccac ggaggatgag attgtcattg acgccacggg aaggaaaaat
    56701 ggccgcggcg cctatatctg cccttctatg gaatgtttca aaaaagctgt aaagagcaaa
    56761 ggcctggaac gctccttgaa gatggcgatt ccaaaggaag tgtacgaggc attggaaaag
    56821 gagatggggc agattggaca gcagtaaaaa ggcgctgaac ctcttgggaa ttgcaaccaa
    56881 ggcaggcaag acggccagcg gagaatttat gacagagaag gctgtgaaag agggccgggc
    56941 ttttctggtc ctggtatcag aggaggcctc tgtcaatacg aaaaaaatgt ttaccaatat
    57001 gtgtacttac tataaggtcc ccctttattt tttcggtacg aaagaagaac tgggccactc
    57061 catgggcaga gagatgcgcg catctgctgc cgtactggac agcggtttgg cgaaagcact
    57121 cgtgaaacag ttgaatcaga atggaggcgg tgtaaatgag agttaacgaa ctgtcaagag
    57181 aacttgggaa gacaaataag gaagttctgg atctgctgaa aaagcaggga tatgatgtga
    57241 agagccattc ttcgaacata aacagcgatc agattgatgc cgttaagagg tgcttttcag
    57301 agcgccctgc gcagagggaa caggtacaaa aggaaagaac aggaaaggcg gaagcagcga
    57361 gagtggaaga gattaagaga gaaccagtaa gaacagaagc agacggaaac ggaacagccg
    57421 agccgccgaa gaagaggatt acggctgtat accgtccgca gaacagcacg gcaaagggaa
    57481 ccggaagcaa ggcaggcgga cagagaacag gacgccaggg ccagggcgcg tccagccagg
    57541 gaaaccgaga cggccaggga aatagagatg gccagaaccg cggctacgga agagacggcc
    57601 agggaaatag agatggccag aaccgcggct atggaagaga cggccaggga aatagagatg
    57661 gtcagaaccg cggctacgga agagacggcc agggaaatag agacggccag aaccgcggct
    57721 atggaagaga cggccaggga aatagagacg gccagaaccg tggctacgga agagacggcc
    57781 agggaagcag agatggccag aaccgtggct acggaagaga cggccaggga aatagagacg
    57841 gccagaaccg cggctatgga agagacggcc agggaaatag agacggccag aaccgcagct
    57901 acggaagaga cggccaggga aatagagacg gccagaaccg cagctacgga agagacggcc
    57961 agggaaatag agacggccag aaccgcggct acggaagaga cggccaggga aatagagacg
    58021 gccagaaccg cggctacgga agagacggcc agggaagcag agacggccag aaccgtggct
    58081 acggaaaccg cgacggacag aggggcagaa gcggttcctc caagccttcc tttgacggac
    58141 cagttgttca gaagccgcag aatacaaagc agaataagaa caactataag aacgattaca
    58201 agaacgataa gtacagcaga ccagaccgcg aggaggagat gcgctccaaa tccggcagag
    58261 gaggaaagcc tggaaagggc gccttcatta tgccgcagaa gaaggaagag ccgaaggcag
    58321 agcaggttaa gaccattgtg cttcctgaga caatcaccat caaagagctg gcagagaaga
    58381 tgaaaatgca gccgtccgtt atcgtgaaga agctgttcct tcagggaaca gtcgttacca
    58441 tcaaccagga ggtggattac gataaggctg aggagatcgc tatggagttc gatattctct
    58501 gcgagaagga ggagaagatc gatgtgatcg aggagctgct ccgggaggac gaggaggacg
    58561 agaaggatat gacagagcgt ccgccggttg tatgtgttat gggacacgtt gaccacggta
    58621 agacctccct tctggacgct atccgccaga ctcatgtgac agccaaggag gccggcggaa
    58681 tcacacagca catcggtgct tatgtggttg agaaaaacgg ccagaaaatc acctttttag
    58741 acacacctgg acacgaggca tttacagcca tgcgtatgag aggagccaag tccacagata
    58801 tcgctatcct ggttgtagct gcagacgacg gagttatgcc tcagaccgta gaggcgatta
    58861 accacgccaa ggcagccgga gttgagatta tcgtggctgt caataagatc gataagccaa
    58921 gcgccaacgt agagaaggta aaacaggagt taatcgagta tgaactggta gctgaggact
    58981 ggggcggaag cacagtattt gtgcctgtat ccgcacacac cggcgaggga atcgaggagc
    59041 ttctggagat gattctctta acatcagagg tgaaggagtt aaaggccaat ccgaaccgcc
    59101 gtgcgagagg tcttatcatc gaggcagagc ttgacaaggg caaaggcccg gtggctaccg
    59161 ttctggttca gaagggaacg cttcacgtgg gagatccggt tgcctgcggt tcctgctacg
    59221 gcaaggtccg cgccatgatg gacgacaagg gacgccgcgt gaaagaggca ggcccgtcca
    59281 ctccggtaga gattctggga ctgaacgacg ttccaaacgc cggcgaggta tttgtggcca
    59341 ccgagaacga gaaagaggcc agaagctttg cagagacatt tatctctgag ggcaagaata
    59401 aattaattga ggacaccaag gcaaaactgt ccctggacga tctgttctca cagatcaagg
    59461 caggaaacgt gaaggagctt ccgctgatta tcaaggcgga cgttcagggt tccgtggagg
    59521 ctgtaaagca gagccttacc aagctctcca acgaggaggt tatggtaaag gtaatccacg
    59581 gcggcgtagg agccatcaac gagtccgacg taaacctggc ggcggcttcc aacgcgatta
    59641 tcattggttt caacgtgcgt cctgacgcta cggccaaatc catctccgag cgcgagaagg
    59701 tagacgtgag actgtaccgc gtcatttacc aggctatcga ggacgtggag gcagccatga
    59761 agggtatgtt agacccgatc ttcgaggagc aggtaatcgg ccacgcagta gtgcgccaga
    59821 ccttcaaggc ttccggagtg ggaactatcg caggatccta cgttctggac ggcaagttcc
    59881 agagaggctg caaggccaga attacccgtg acggcgagca gattttcgac ggaaatctgg
    59941 cttccttaaa gagatttaag gacgatgtga aggaagtagc gtcaggttac gagtgcggcc
    60001 ttgtatttga gaagttcaac gatctccagg aggacgatat gattgaggct tacgcaatgg
    60061 tggaggttcc ccgataggga accccgcctt tgcgggaggc cgctggaaag cgaggcaata
    60121 tgcgtaaaaa cagcattaag aatacaagaa ttaacagtga ggttcagaga gagctgagca
    60181 gcattatcag cagagagatc aaggatccca gaatccatcc catgaccacc gtcgtatcgg
    60241 tggaggtgac tcctgactta aaatactgca aggcttatat cagcgttctc ggaagcgagg
    60301 aggcaggaaa ggacaccatc aagggattaa agagcgcgga gggctttgtc cgcagacagc
    60361 tggcaaacag aatcaatctg cgcaatacgc cggaaattgc ctttgtgctg gatcagtcca
    60421 ttgagtacgg cgtccacatg actcacctga tcaatgaggt gacaaaggat ctggacacag
    60481 atgaagatac agagcaggag acagaggagc agctttaggg cttctccgtc tcctgttctc
    60541 gaaaacagag actgcagagc gttcttaaat gagaagggat gatgaatatg aaccagttat
    60601 tggaaagcag gctgaatctg gcgaagacag ccgtgattct gggacacgtc catccggacg
    60661 gagactgcgt aggctccact ctcggacttt ataattatct tacagccaat tatcctgagc
    60721 tgaaggcaga tgtttatctg gatcatccag accggaaatt ttcctattta aagcagtttg
    60781 accgcattca ttgtgaatat gaggagggaa aacgctatga tctgtgcata acctgcgaca
    60841 gcagcgacgc ggagcggctg ggagcgttcc ggccttactt tgatacggca aagcacacgt
    60901 tctgtgtaga tcatcatgtg acaaaccgtg gattcgcaga ggaaaactgc gtagagccgg
    60961 acgccagctc agccagcgag gtggtatgca ccctgcttga catggagaag atcgatctgg
    61021 cggcagccga gtgcttctat acaggaattg tccatgatac aggcgttttc aaattcagct
    61081 gcacctcggg aagaaccatg gaaatcgcgg gaaagctgat ggacaaagga atcgacacca
    61141 cagagattat cgacggcagc ttttaccgga aaacctatgt gcaaaatcag attttaggcc
    61201 gcgccctgtt agagagcgtt ctgttcatgg acggcaggtg cattttcagc tctgtgacga
    61261 agaaagagat ggagttctac ggggtgacga acaaggatct ggacgggatt attgaccagc
    61321 tgcgcctgac tgcaggggtg gaggtcgcca tttttatgta tgagacaggg agcagcgagt
    61381 ttaaggtgag catgcgatcc tgcagatacg tggacgtgag ccagattgca gcctattttg
    61441 gcggaggcgg ccacgtgaga gcggccggat gcaccatgtc tggaacgctt cacgacgtgc
    61501 tcaataatct ggcgccccat attgaacggc agattctcgc atgggaggca gaacataaat
    61561 gtttcacgga gtaatcaata tttacaaaga gcctggctac acctcccacg acgtggtggc
    61621 caagctccgc ggaattttaa aacagaaaaa aatcggccac acaggaacgc ttgatccggc
    61681 agcagaggga gttctccccg tatgtctggg aaaaggaaca aagctctgcg acatgctgac
    61741 agacaagacg aagacctacc aggcggtgat gctgttagga gtttccacgg atacccagga
    61801 taccacggga accgttctct cagagagaag cacagaggga gtggacgagg ccgccgccgc
    61861 agaggctgca gagagcttcg tagggctgta tcaccagatt ccgcccatgt actctgctct
    61921 caaggtgaat gggaaaaagc tctatgagct ggccagagag ggaaaagagg tagagcgcca
    61981 ggccaggccg gtggaaattt tcagtctttc gattgataag atggagctgc caagagtgac
    62041 catgacggtt cactgctcca agggaaccta catcagaact ctctgccatg atatcggaga
    62101 gaagctgggg tgcggcgcct gcatggagca tctgctccgg acccaggtgg atcggtttct
    62161 ggtaaaggac agtctgacct tatcccagat ggaggagctt gtgaaggaag ggactgtcca
    62221 ggagaggatt gttccggtag atcagatgtt ttctcatttt ccggcctttt attcggagga
    62281 tgaaacgctg gacaggcttt tatcaaacgg caactttttc ttaaaaagcc aggccagagg
    62341 gcggtgggaa ccggacgcag ggcaggatac gccggaacag gacggcagca tgtgccgtgt
    62401 gtatgacgga tccggccgtt ttatcggagt ttacgagtac agggcgtctg aaaagaagtg
    62461 gaagccaagg aaaatttttc tgggaggaga ctagccatgg aatacatcag aggaaccagg
    62521 gaatttcaga ttgaagagcc gacagccgtt acccttggaa aatttgacgg acttcacaga
    62581 ggccacaaaa agcttctgga ggagctgttt cgattcaggg aaaaaggctg caagacggct
    62641 gttttcacct ttgagacggc tccgggaacc ctgattcgga agaagctcca gaccatgatt
    62701 accacaaatg aggagcggta tgagaatctg agagacgcag gcgtcgatta tctggtggaa
    62761 tacccattta atgagcaggt ggcttccatg agcccggagg agtttgtcgt tcatgtacta
    62821 aagggacaga tgaacgcaga ggccattgtg gcaggcacag attttcactt tggacggaac
    62881 cggagcggag acgtagcgtt tttaaaggcc aatgcagaaa aattccgcta tgacttaact
    62941 gtcgtggaaa aagccatgga cggagaacgg gaaatcagca gcacctacat cagggaggag
    63001 ctggccgccg gaagaattga gaaggctaac gaactgttag gctatacgta ttctatccag
    63061 ggccgcgtgg ttcacggaaa acatctggga accggcatgg gatttcccac cgtaaatctg
    63121 cttccgccgt cccagaagca tctgccagcc ttcggcgtat atctgtcgga ggtggagatt
    63181 gatggaaagc tctatcctgg aatcacaaat atcggcagaa agcccactat caaaggagag
    63241 catcctgcag gcgtggaaac ccatatctat gactggacaa gagatattta tgggaaggac
    63301 gtgaaggtga gacttttgac cttcatgcgc ccggagaaaa agtttgattc ggtggaggaa
    63361 ttaaaagccc aggttctgca cgataaggaa gaaggcagaa tctggcacca gaaccggctg
    63421 taagaggttc agaacctgtc aatcagaata cgaaaaacaa aaaaggcaga tgcaggacgt
    63481 acccgttcag ggtgaagtcc tgtatctgcc ttttgacagt gtctggctgc tgtgaaattt
    63541 ttattatggc tctttgtcaa gagttggggt aaatgtattt ttgaggcaca ggaatgatgt
    63601 ttctgtgcct ctttacgtta gggctagaaa gattcgattc ctaaaatttt taaagttccg
    63661 atatccaaag gcatttcgtt tgattacttt aatggcattg tttgttccct ctgtaaaacc
    63721 atttgtatag ggacaatcga atgcgttcag aatgtatttt gaccagttcg ccagcatggt
    63781 taagcaggcg tgaaattctt tcagctgact ggcctgggct gcaagcagaa agaacttcag
    63841 cttttttgtg gcttctgtac gagacattga tttcataaaa tcataaaata gttctttcaa
    63901 gtggtaggca attgcaagat cttccgattg tgacagcata accgccagtg catccatact
    63961 ttcttctttt agtttgcttt tgtgggtcaa aaggagtttc cggcttcgtt tgaaatattt
    64021 ccgtttgtct ggatgaagct gtttctgaat ccgcttcctt acattttcca aagcccaggt
    64081 aacataacgg acaacgtgaa acttatcaat aacaatggta gcttgaggaa aataatcttt
    64141 tgccagttct cgataaacct tattcatatc catgacaata aaacggactt cttttttatt
    64201 cttgaagcct tggaaatact gctggagtga gacctgcgaa cgggaaggaa gaatatcaaa
    64261 cagggaatgt ttatcaggac aggtaagaat cgcctgaaat ttttctcctc cggcattgcc
    64321 tttgaattca tcaatggaaa ggacagtcgg aagccggtct ggttttggga actgaactgc
    64381 tttcagcctg cgaaagatgt aggaatctga taaatccaaa agcctggaaa cagaacggac
    64441 acactgtcgc tccgaaagta gatgaatggc ataaaaagca agacgggtag tggtacggca
    64501 atgctttgca gccagggaaa aaggctcgta aaagtgtttg ccgcagagag gacagtgata
    64561 gcggcgtttc cggtaatgga ggaaggtatg tttgcccatg atcggaaggt ctttgatgat
    64621 ggaaatgcga taatcatgga ctttatctgt cagcccgagg caatgagggc aggtacaagc
    64681 tttgcgaggg agagaaaagt gaatatgaat ttctgtatta gaagaagtaa aatcagagat
    64741 aattatctct tccaattcca ggagttttgc ggtaaaatta gaagtaggca tagagttcaa
    64801 tcctttcata atttggtgtg gtaacttaat tatataggaa aagaatctct atgcctattt
    64861 cttttttact ttacccccaa gtaaagtgta caacctttat tatgagacgc agttcatgaa
    64921 aaacctgcgg tgagaagcag gttataaatg actctcctct gcaagcatcc gttccacctc
    64981 gtcgcaggcg atcctgatgt attcggagag agaaagttct cggcagccga cgaccgtatg
    65041 gctgcagcgg tggctgacag gaatcagaag cttgtgggcc ggacttttcc ccaccgccgc
    65101 cgccatagtc tccgtcacct cgccaagcag agcgtcggcg atgacgatgc ccacaggccc
    65161 gatgatgaca tctgccgagc ggctgtttac caccacggga ttctctcctg tggcgcccca
    65221 gtcggctccg gctttcatca tggctgcggt ggcgatgctg ttagtcccta cagcggtgag
    65281 aggaagatcc ggaaaccgct tttttaactg ctccacaatt cccttcccca tacggccgcc
    65341 ctggccgtct ataattacaa tctgaagtct gttcatccta tccctctctc tgtcgaataa
    65401 aagaaaaccg gcctgtctgc cataagagcc gccagccgga aataataccc cactatatcc
    65461 ttgtcagtat agcacaaaaa ccagaaaaat ggaagacaaa attctacatc aaaactaaaa
    65521 ttttttattt acagagtctg atttttctat tataatgctg ataatggtta actagggcct
    65581 gaatgtgagg aggctctnnn nnnnnnnctg gcagacacaa agaaagtaaa cgcaaactgg
    65641 tgacaatgag agggagaaaa catgagaaga aatgacattc acaaagtaat gattattggc
    65701 tccggtccaa ttatcatcgg acaggcatgt gagtttgact actctggaac tcaggcatgt
    65761 aaggctctta aaaagctcgg ctatgagatt gtgctggtaa attccaatcc ggctacgatt
    65821 atgactgatc cggagacagc agacgttacc tatattgaac cgctgaatgt agatcgtctt
    65881 gagcagatca ttgcaaagga gcgtccggac gcccttcttc cgaacctggg aggacagtca
    65941 ggattaaacc tgtgctccga gctggcggct gcaggcgttc ttgacaaata taacgtacag
    66001 gtaatcggcg ttcaggtaga cgctatcgag cgcggcgagg acagagaaga gttcaaggag
    66061 accatggaaa gccttggaat cgagatggcc agaagtgagg ttgcctattc ggtagaccag
    66121 gctctggaga ttgctgataa gttaggctat ccggttgtgc ttcgtccggc ctataccatg
    66181 ggcggcgagg gcggcggcct tgtatataac gtagaggagt taaagactgt ctgcgccaga
    66241 ggtcttcagg caagtatggt aggacaggtt ctcgtcgagg agtctattct gggatgggaa
    66301 gagctggagt tagaggttgt ccgcgactcc aagaacaaca tgatcacagt ctgctttatc
    66361 gagaacatcg atccagtcgg cgttcacaca ggcgattcct tctgttccgc accgatgctg
    66421 actatctccg aggaggttca gaagcgtctt caggagaagt cctacaagat cgtagaggct
    66481 atccaggtta tcggtggaac caacgtgcag tgggctcacg atccgaagac agaccgtgat
    66541 attgtcattg agatcaaccc gcgtacctcc cgttcctcag cccttgcttc caaggcgaca
    66601 ggtttcccaa tcgcccttgt atccgctatg ctggctacag gcatgacact ggacgagatt
    66661 ccatgcggaa agtacggtac cctcgataag tacgttccgt ccggcgatta cattgttatc
    66721 aagttcgcgc gctgggcatt tgagaaattc aaaggttccc aagataaatt aggcacacag
    66781 atgaaggctg taggcgaggt tatgagtatc ggaaagacct acaaggaagc ccttcagaag
    66841 gcaatccgaa gcctggagag aggccgctac ggcttaggcc acgcaggctt cgaaggaaag
    66901 agcaagaagg agctgctctc catgctccac acagtttcca gcgagcgcca gttcatcatg
    66961 tatgaggcct taagaaaggg cgctacagtg gaggaacttc ataatctgac acagattaag
    67021 agctatttca ttgcccagat gaaggaatta gtggaggaag aggaagctct tctcaagtat
    67081 aagggacagg ttcctccggt tgaggtactg cgtcaggcca agttagacgg ctttgctgat
    67141 aaatatttaa gcgagcttct ggagatttcc gaggaggcag tccgcgatgc cagaacagag
    67201 gcaggcattg aggaaggctg ggaaggcgta cacgtaagct caacagagga ttctgcatac
    67261 tactactcca gctaccacat taaggacgag agcccgtgta cagacaataa gaagattatg
    67321 attctcggcg gcggcccgaa ccgtatcggc cagggtatcg agtttgacta ctgctgcgta
    67381 cacgctgcag tagccctgaa ggagctggga tttgagacca ttatcgtaaa ctgcaacccg
    67441 gagacagtat ctacagacta cgatacctcc gacaagctgt attttgagcc gctgacactg
    67501 gaggatgtat taagcatcta ccataaggaa aaaccgcttg gcgtgattgc tcagttcggc
    67561 ggacagactc cgttaaatct ggcagctgat cttaagaaat acggcgtaaa catccttgga
    67621 acaactccgg agactatcga catggcagag gacagagact tattccgcga gatgatggat
    67681 aagttaaaca ttccgatgcc tgagtcaggt atggctgtca atgtagacga ggctcttgcc
    67741 attgccaaca agattggata cccggttatg gttcgtcctt cctacgtatt aggcggacgc
    67801 ggtatggagg ttgttcatga tgataacgcg ctgtccttct atatgcagca ggcagtaggc
    67861 gtgacaccgg atcgcccgat tctgattgac cgtttccttc accatgcgac cgagtgtgag
    67921 gcagatgcta tcagcgacgg cgagaacgta ttcgttccgg ctgttatgga gcacatcgag
    67981 ctggcaggaa tccactccgg agactctgca tgtatccttc cgtccagaaa tctgactctc
    68041 gaccaggtag agacaatcaa ggattacacc agcagaatcg cgaaggagat gcacgtagta
    68101 ggtctgatga acatgcagta cgctatcgag gacggcgagg tttacgtgct ggaggcaaac
    68161 ccgagagcat ccagaactgt gccgctcgta tccaaggtat gcaacatcaa gatggttaag
    68221 ctggctacag acattatgac ttcctacctg acaggacgtc cttcaccggt tccggagtta
    68281 aaggagaaga aaattcctca ctacggtgtg aagatgcctg tattcccgtt caagatgttc
    68341 ccagaggttg acccggtatt aggaccggag atgcgctcca caggagaggt tctgggcatg
    68401 tccgccaacg taggagaggc tatctacaag gcgcaggagg cgactcagac aagacttcca
    68461 gctaagggaa ccgttctgtt aagcgtcaac gacaaggaca aggcagagct catcgaggta
    68521 gccaacggct tccacgagtg cggcttcgag ctgatgggaa caggaagaac ctgcgacatt
    68581 atggtagctg caggacttcc ggccaagaag gtagctaaga ttgacgaggg ccgtccgaac
    68641 atcctggata agattacaaa cagagaggta gacatcatta tcaatactcc tctggacaga
    68701 aagggtatgg gcgacgacag ctacatcaga aaggcagctg ttaagggcaa gattccttac
    68761 tttacaaaca tggcggcagc caaggctacg gttcaggctc ttagaaccat taagaaaaac
    68821 ggccatctgg gcgtgaaatc cttacaggaa ttccacagcg agatcagaga gcagtaatct
    68881 taaatataaa aaaacaggtt ccggcagaga agaaattctt tgccggaacc tgtttttttg
    68941 ctctctggaa tacataattt gctgatttga aacttttcgc ggcagaaaac agtctaataa
    69001 atagaatgaa ataagaacac tgcagtgacg gaaaggagcg caggaaaatg agtgcagcgg
    69061 ctgagctgca gacagagagg tacccatgaa agagacatta tatgaaacgc tgatcagctg
    69121 catcactgaa aatcaaaacc gtttttaccg ggtggcatac agctatgtta aaaatgaaga
    69181 agacgccctg gatgcagttc agaacacagt ctgcaaggca ttggagtcct acagaaatct
    69241 aaaaaacgcg gaagccgtcc ggacgtggtt ttacagaatt ttaattaacg aaagtattga
    69301 cattatgagg cagagaaaga aatttctgct gtcagaagat tatcccggcg cagaaaaaat
    69361 atacgaggag cggggatatg aaccagaaga agagatagcc agagagctgg aggatttaga
    69421 ggaaggtacg cagcaaatca taaaactcag attttttgaa gaattgtcgt taaaggaaat
    69481 ttcggagatt acaggaatcg atttgagcac agtcaagacg aagctttaca gaggccttaa
    69541 aagcttaaag gaatcgatcc aggaggtgga cgaatgagcc ggttagaaga tatgaagaaa
    69601 gattatgaga atgtaaagat tcctgacgag ctgaatatca gaatcgaaaa ggagatagcg
    69661 aagtccagag ccagagaaaa gatgattcag ctgagccaca gaaagaggtg gttcaggaac
    69721 acggcagcag ccgctgcggc cgtatgcgtg gttttaccac agcgttaaat accagtaccg
    69781 cttttgctga ggaggctgcg cagcttccgg tgattggaac gctggccagg gtactgacat
    69841 tcagaaacta tgaggcggag aagaatggaa tcggaatcgc ggtggaggtt ccaaccatcg
    69901 acatgattca gacagagaca ggaatccagg tggatgaagt caaccagcag atttatgatc
    69961 tctgcagaca atatgcagac gagtacagaa aagcgtttct tgatacaggc gggacggaag
    70021 aagagtggga agcccacaaa atacagatta acgtaggcta tgagattaaa tcacagacgg
    70081 atcagtacct ttccttcatc gtacggggaa gggagagctg gaccaccgcc tatagcgagt
    70141 ctaggtatta caatatcgac gtgaacacag gaaagagagt aactcttgcc gatttcttcg
    70201 gaaaagatta tgtggaagct gtcaatacag acatcagaga gcagattgct cagagaaaag
    70261 aagcgggaga ggttttctgg acagaggagg aaggcggatt ttccggaatc acagaggatg
    70321 caaaattcta tgtcaacgaa gccggaaatc ctgtcattgc ctttgaaaga tatgaaatcg
    70381 cgcccggttc gtccggagag atagaatttg aaattcaacc gtaaatggca gaaaaataaa
    70441 gaaaatggag gaaaatatta tgaaaaaaac aaaccttact ttagcggcgc tgctggtatc
    70501 aatcgcggcg gcatcatttg cagtgacagg ctgcggcaaa aatgagaagg cagaggagac
    70561 cacagcatcc gagatgcttg agacatccag cggatatgag gacaatttcg ctgtggacag
    70621 cagggcggcc gctgagtttg cagataagat taaagaggca gtagcggctg aggatctgga
    70681 agcgctggcc gatctgacgg catttcccgt ctatgtggac attgaaaatg caaatgacgt
    70741 gaagacaaga gaggactttc ttgctctggg agccgaagcg atctttacag aggagcttaa
    70801 aaagtcagct gccaatgccg atacagaaaa tatgcagccc agcatggcag gattttccgt
    70861 ttctgacgga ggttcagcca acatcaactt cggcgtgaga gacggcgttc tggcagtgaa
    70921 cggaattaat tactaaagaa gagcttaaag gttttatcaa taataaaaaa tgtttataga
    70981 aaaaatcaat tgacacttcc aggaagcggg gcctgggata attgacaggg cagaagggac
    71041 agccgtataa tagcgtcagt atacaagaga cttggaacgt ctcctgtaca ctggcgctaa
    71101 aaaaatgagc aaaatgaata cacaggaggc acagacggat gaagcagctt gatatgagag
    71161 gaaaggcatg tcccatgccg gtaattgaga caaaaaaact gttggaggaa ctgaaccggg
    71221 cagaggcggt gaccgtgctg gttgacaacg aaatcgcagt ccagaatttg acaaagctgg
    71281 cagggcatga gggaatggac gtgtcaagtg acaaacattc tgacaaggag tttgctgttg
    71341 tgttcacacc ggcagaggga ggctctgcag aagctcagag cacagaggga caggagacgg
    71401 cgcaggagga cctgatcgtg gaaaatcaca ttgcgaaggg aagagtagtt gtcattgctt
    71461 ccgacaagat gggagagccg gaggaggagc ttggaaagat tctgattaaa ggatttatct
    71521 acgctctgag ccgtcaggac gcgctccctg aaacaatcct gttttacaat ggaggagcga
    71581 aactgacggc agagggaagc gagtccgtgg aggacttaaa gtacatggca gaacagggcg
    71641 ttgagattct gacctgcgga acctgcttaa agcatctggg gctggaggac aagcttcagg
    71701 taggagctgt ttccaatatg tacgagattg cggagaagat gacagaggca ggacagctga
    71761 taagaccata gaagacagga agcggaggcg gcatctggac ggcgggagac aaaaaactac
    71821 cggacagagt ccgcctcctt tttgtgcctt tttttgcaga taacagggaa agagaagttt
    71881 tctgtcatat tttgttgtat ggaaagtaaa aaatatacaa aaaatcactt tattattcgt
    71941 gcgttttgac gtataataaa aaagcggggt atccgccgaa tgaaagacag caggagaaaa
    72001 gacatgtatc tgttagttac gaacaacggc ctgtgttttg agaagtatca gaaccgggta
    72061 aaggtagatt atctggagga tggatcctac ctggacgtgc tggtgaaagt cagggattac
    72121 gtacagaagg gatacagaat tgagactcat cccatggcgg gaagcattaa gcccaatcag
    72181 acgccgtttc gcacggttct tgtttccgat gagaagatgg atggaaacga gatgattgaa
    72241 aatgagctga tgattgagga cgcagtcctt atgacgagaa agtttctcag cgaccacccg
    72301 gtcagagact gggagaaatc cattgtcaga gattttggac aggtggattt ggaactgatc
    72361 agcggagcga ttgacaggat tgtttaaaaa acagaggttt tttgaaaatt gacaggaaaa
    72421 tcctgaaaat tgtcatctga gcggcgataa atgtcaaact tatgacagga tatatggcaa
    72481 agttgccaaa gttgccagaa aaaacacctg gaaagccggt ttgaaacagc tggaatctcc
    72541 cggaagaagc ggcgcataaa aaatttatgc gggggaggac ttagaaaaag ctagtaaaat
    72601 caagaggttt taccagggaa aaagatattt ttttaccgct tccacaatat ttgaaaaata
    72661 tggcatacta cttgctatat ttataaagcg aagagtaaat cttctgccgc aaatacaaaa
    72721 ataagaaaag gaggtcaggc attcatgaaa cttgagttag gtattattcc tgtaaaagac
    72781 atccagtttg gtccggagtc caaagtggag aatggagtta tctatgtgaa tgcagatgag
    72841 ttaagggctc ttcttcttga ggatgagaac ctgaaatctg tagagtttga catcgctaga
    72901 ccaggcgaga gcgttcgcat tatgcctgta aaggatgtta ttgagccacg agtaaaggta
    72961 agcggagagg gcgctatgtt cccgggtatg atttccaagg ttgctactgt tggaagcgga
    73021 agaactaacg tactccgcgg atccgcagtt gttacaacag gaaagatcgt tggtttccag
    73081 gagggaatca tcgacatgtg cggaactgga gctgagtaca caccattctc caagttaaac
    73141 aacctggttg ttatctgcga gccggttgac gatatccaga agcacgctca cgagaaagca
    73201 gtccgcatgg caggcttaaa ggcagctgac tacatcggaa agctggctaa ggagatcgaa
    73261 gctgaggaga ttgagacata cgagacagag acagtgaagg agggacttga gaagtacccg
    73321 aaccttccta gagtcgctta tgtgttaatg cttcagagcc agggactgat gcacgatact
    73381 tacgtatatg gcgttgatat gaagcagtct ctgccgacaa tcattaaccc gactgagaca
    73441 atggacggag ctatcttaag cggtaactgc gtatccgcat gcgataagaa tacatcctac
    73501 caccacttaa ataacccggt tatcaaatcc ttatttgatc agcacggaaa gacattaaac
    73561 ttcgtaggcg ttatcatcac aaacgagaac gtttacctgg cagacaagat gcgttcctct
    73621 gactggactt ccaagctctg caagtggtta gatgttgacg gcgctatcgt ttcccaggag
    73681 ggattcggaa acccggatac agaccttatc atgaactgca agaagatcga gggccagggc
    73741 gttaagactg ttatcatcac agacgagtac gcaggacgcg acggcgcttc ccagtcctta
    73801 gcagatgcag atgcagcagc agacgcagtt gttacaggcg gaaacgcaaa catggtaatc
    73861 actctggagc cgaaggacaa agttatcgga tatccggaag ttgcagatat tattgccgga
    73921 ggtttcgacg gaagcttaca ggcagacgga tccatcgtag cagagcttca ggttatcacc
    73981 ggagctacaa acgagatggg cttcaataag ttaagcgcca gataggagga aatcatggga
    74041 aaactgaaat ttgtccatta tattaatcag tttttcgcaa atatcggtgg cgaggagaaa
    74101 gctgactatg caccagaggt aagagatgga gttgtaggtc ctggacttgc attcaatcag
    74161 gcattcggtg aggaagctga gattatcgca actgttatct gcggagactc ttacttcaac
    74221 gagaacgtag actctgctac agagactgtt cttaatatga tcaaagagaa agcgccggac
    74281 ggcgttatct gcggacctgc attcaacgct ggacgttacg gcgttgcctg cggtacagta
    74341 gcagcagcag ttaaggagca gcttggactt cctgtagtaa caggtatgta caaggagaac
    74401 ccaggcgctg atatgtacaa gaacaaggta tatatgtgcc cgacaaagaa cagcgcagct
    74461 ggtatgagag acgctgttaa gaagatggct cctttagctc ttaagcttgt taagggcgag
    74521 aagattggct cttccaagga agacaactac atgccgaacg gcaagcgtgt aaacttcttc
    74581 gaggacaagc gtggcgctga gcgtgccgtt gagatgctcg ttaagaagtt aaacggcaag
    74641 gagtacgaga cagagtaccc aatgccaagc ttcgaccgtg tagctccagg cgcagcaatc
    74701 gttgatatgg ctcacgctaa gatcgcttta gtaacatccg gcggtatcgt tccgaagggc
    74761 aacccagatc acattgagtc ctccagtgct tccaagtacg gacagtacga catcgagggt
    74821 gttatggatc tgacagagga gacatacgag acagctcacg gtggatacga tccagtatac
    74881 gctaaccagg atgctgaccg tgttcttccg gttgatatcg ttgaagagtt catcaaggaa
    74941 ggcaagattg gaagcctcca caaatatttc tataccacag ttggtaatgg aacagcagta
    75001 gcaagcgcaa gcaagtacgc taaggaaatc ggacagaaac tggttgatga ccatgttgac
    75061 gcggttatcc tcacctctac ctgaggcacc tgtacacgtt gcggtgcaac gatggtaaaa
    75121 ggcattgagg cttatggaat tcctgtagtt catattgcaa cagtagttcc gatttcactt
    75181 acagttggag caaacagaat tgttccggcc attgctattc ctcatccact tggaaaccct
    75241 gctctttccc tcgaggaaga gaaagatatc agaagaaaga tcgttggaaa ggctctggaa
    75301 gcgttacaga ctccggttga cgaccagacg gtttttgaat ggaagtaatc tgagagcggg
    75361 acggtacgct ttctgatgaa gataatttgc ggcccccgga aacgggggct gtgaagggag
    75421 aaattgagat gggcaagatt tatgacgtaa ttatcttagg cgctggtcct ggcggactgg
    75481 ctgccggtct gtattccgga agatatcgtc ttgacactct cgtaatcgag aaggcaaaag
    75541 acggtggaca gatcgcaatt acagacgaaa ttgaaaacta tcctggacag aaggtagaag
    75601 gcgagagcgg tccttcctta atcgcacgta tgacacagca ggttgagaag ttcggcgcag
    75661 agcgcgtgac agatacaatc aacaaggttg agttagaagg tccggttaag aagctgtacg
    75721 gaacaaaggg cgagtatgag tgcaagtgct taatcatcgc tacaggcgct tatccgcgtc
    75781 caatcggctg caagagagag ggcgagttcg taggcaaggg agtttccttc tgcgctacct
    75841 gtgacgctaa cttcttcgag gacttcgagg tattcgtagt cggcggcgga gactccgctg
    75901 tagaggaggc tatgtacctt acaaagttcg ctagaaaggt tacaatcatt cacagaagag
    75961 acgagctgcg cgctgcaaaa tccatccagg agaaggcatt caagaatccg aagctgcact
    76021 ttatgtggga tacagtagta gacggacttg agggagacga gatcctttcc gctatgactg
    76081 ttaagaacgt caagacaggc gagatcacaa gagtagaggc tgatccggag gacggaatgt
    76141 tcggcgtatt cggcttcatc ggatatattc cgagaaccga tctgtttgag ggtgtgattg
    76201 acatggagaa cggttacatc aagaccgacg acaacatgca caccaatatc cccggtgttt
    76261 ttgcggcagg agacgtccgg gttaagtctt taagacaggt agtaacagca gccgctgacg
    76321 gcgctatcgc tgctcagcag gcagaaaagt atatcgcaga gatggaataa aggtaaattt
    76381 cacacacggt agtgttgaaa tttaccgcca cccaaacgca gcgaagcgga gttcgggttt
    76441 tccgcggcga ttcccgttcc agtgaatggg gaatttgtaa gtgaaagcaa aattcagata
    76501 gggaaggtga aagaaaatgg ttgatttaac aaaggaaaac tttgaagagg aagttttaaa
    76561 agcagaagga accgttttag ttgatttcta tggagacggc tgtgttccat gccaggcttt
    76621 aatgccacat attcatgcta tggaagatgt ttatggaaag gatattaaat tcacttccct
    76681 gaacactacg aaagcccgcc gtctggctat cggacagaag gtattaggcc ttccggttat
    76741 cgctatctac aagggtggcg agaaagttgc tgagtgcgta aaggacgacg caacaccaga
    76801 gaacgtagag gctatgatta aggctaacct gtaatcagga ttgcttcatt gcatttacat
    76861 tgaaaaaact gctgaaaatc tttcgagttt ccagcaggac aagctgggca aacagcctgg
    76921 tttgtgatat aatagttccg ctagaaccca cgaaagtggt gtctatacaa aaaattagaa
    76981 gaaggaggaa tcggaaatgg caattttaaa cggtaaaaaa accattatca ttggcgaccg
    77041 tgacggaatt ccgggcccgg ctattgaaga gtgtgtcaag acagccggcg ctgaggttat
    77101 ttattcctct acggagtgct tcgtctgaac gtccgcaggt gccatggatc tggagaacca
    77161 gaagagagta aaagatttcg cagagcagta cggtgcagag aatgtagtag taattctcgg
    77221 tgcagcagag ggagaggcag caggcctcgc cgctgagact gtaacagcag gagatccaac
    77281 tttcgcaggt cctttggcag gagtccagtt gggacttacc gtatatcaca tttgtgagga
    77341 tgaaattaag gcagaagtag atcctggtgt ttacgacgac cagatcagca tgatggagat
    77401 ggttatggat gttgatgaca ttcacaacga gatgtcttcc atccgtgatg agttctgtaa
    77461 atacctctaa ttgagcgcgc ctttaagcgc tcgcgtatat ttcccggcgg acgatgttct
    77521 gccgggaaat tcttaaatat ggaacaattt ttaaatttaa atcatatatg aggtgaataa
    77581 catgggcggt tatcctgtat taaaaggagc aagctatgta cttgcagtag ttccggatat
    77641 ggttcttgag aacggaacca cacagactac agagaagatt gtaaatcctg attctgaata
    77701 cttaaaggag cttccaaagc acttaagaag ctttgaggat gcagtttcct accttccgaa
    77761 ccagatttac atcggaaacg agaagccaga ggctttaaga ggaatcgagt tcccattctt
    77821 caacacaaag tgggagaatg cgaagagaga cggaaaatac ggccagatta tgccgcagga
    77881 cgagttctac ggactgatgc agatctgcga cgtatttgag ttagtacacc ttgagaaggc
    77941 ttttgctgct tccgttaagg agaaattagc tgctctcaac atcctgacag acgagcagtt
    78001 agcagtatta gacggaaatc agtctacaga ggacgacatc aaggctttag tagagggcga
    78061 gcattccgag cctctttacg acggcggaaa attagtgggt gctatcaaga gagctcacga
    78121 cgttgatgta aacctctccg ctcacaccat gcttgagaac atcgttgcca aggcatccag
    78181 cgtactggct ctgatcgagt tagtaaagaa gggcggagta gatccgaacg agattgacta
    78241 cgttatcgac tgctgcgagg aggcctgcgg cgatatgaac cagagaggcg gcggaaactt
    78301 tgccaaggct gctgctgagg ttgcaggttt cacaaacgct actggatccg acgtaagagg
    78361 cttctgtgca ggaccggcac acgctatcgt tcacgcagct gctctggtac agtccggcgc
    78421 attcaagaac gtagttgtaa cagccggcgg atgtacagct aagctgggta tgaacgctaa
    78481 ggatcatgtg aagaagggcg ttccggtact tgaggactgc gtagcaggct tctctgtatt
    78541 aatcagcgca aacgacggcg taagccctgt actccgtaca gatatcatcg gccgccacac
    78601 aatcggaaca ggcgctgctc ctcagaacgt aatttcttct ctcgtaacag ctccgcttga
    78661 ggcagctggt ctgaagatcc ttgacattga caagtattca cctgagatgc agaacccgga
    78721 tatcacaaag ccggcaggag caggagacgt tccagaggct aactacaaga tgatcgctgc
    78781 attaggcgta aagaagggcg agcttcagag aaatgagatc gcttccttcg taagcgagca
    78841 cggtatggtt ggctgggctc cgacacaggg ccacatcccg tctggtgttc cgtacatggg
    78901 cgcattaaga gacgagatcc ttgcaggcga gacaaagaga gccatgatta tcggaaaggg
    78961 aagcctcttc cttggaagaa tgacaaacct gttcgacggt atctccttcg tagttgaggc
    79021 aaatgacggc tccggcgctg acgacggaca ggctgtagat gagaagcaga tcaagtccat
    79081 gatcggccag gctatgaaag aattcgcaaa gggacttctg gaagagcagt aaaatatctg
    79141 gaaaggacga aaaattatgt ctgaagcaaa gattaagaaa atgatcgcag agacctttct
    79201 ggaagttgcc gatgctcttg agacaggccg ttatggcaag aaggcagtga tcggatttgc
    79261 ctgcgagggc agcgagcacg gccaggagaa cattgacaga gcctttgagc tggcagtaag
    79321 gaagggactc accccttaca tgatcgaagg ggaagatatt cataaaaaga tggaggagct
    79381 gctggaatcc ggtgagattg acgctgccgt taccatgcac tatccattcc cggtaggcgt
    79441 ttctactgtt ggaaaaatca ttaccccagg tatgggaaag gccatgtatc tggccacaac
    79501 tacaggaacc tctgacacag atcgtgtttc tgctatggtt aagaatgcta tctacggtat
    79561 catcgcagcc aaggcagacg gaatcgagaa cccgaccgtt ggtattgcca acattgacgg
    79621 cgcaagacag acagagaagt acctgcttca gttaaaagag aatggctatg acattcattt
    79681 cgctgactct gcccgtgcag acggcggaat cgtaatgaga ggaaacgacc tgttaggcgc
    79741 ttccgcagac gttatggtta tggattccct gacaggaaac ctgatgacaa agatcttctc
    79801 cgcttacaca acaggcggaa gctacgagtc cttaggtttc ggctacggcc cgggaatcgg
    79861 cccagacttt gacaagctgg ttatgatcgt ttccagagct tccggcgctc ctgtaatcgc
    79921 aggcgctatg gagttcgcta caaacctgat caaccatgac tggaagaaga tcgtaaagga
    79981 tgaatggaag aaggctgaga aggctggtct gaagtccatc ttagacgaga ttaagaaggc
    80041 caacaccaag aagtctgacg gggacgatga agaggttgcc atgcctccga aggagatctg
    80101 tacagagcag atcccaggca tcgaggttat ggatctggag gatgcagtta aggttctctg
    80161 gaagaacggc atctacgctg agagcggcat gggatgtaca ggcccaatcg tcagaatggc
    80221 ggctgataag aaggagaagg cagtagaact gctgacagca gccggatata tcggctaacg
    80281 aacggttaaa gaagcagaag ccgagagaac tctcaggaaa agttttcctg ttccaatgga
    80341 agtcaccgaa aacttttcct ggagttctgg cccagcagta caggcgttga aagaaagttt
    80401 tttgtggctt ttccggaaca aaaaacttcc tttctccgca ctgttcagct aatttttttc
    80461 gattttattt gacaaaaaac taaatatagg atatagtatt ataagctatg cagaatgagg
    80521 aggcagatag gttgctggtg tgcctcgcgg tcttcaaaac cgttgtgggg agttaggagc
    80581 tccctgggtg ggttcgattc ccacctcctc cgtttctttt catctgatag ttatttagga
    80641 aggataatat aatatgggag aaagacagga attactgaga aaaatcccta agattgatga
    80701 ggtgctgcag gacgagcgtc tcattttttt tatggaaaaa acgccgcgca gcgtggtagt
    80761 ggaggctgtg cgccagcaga ttaacgagct gagaaacgga attttacagg gaagcattga
    80821 agaagccaca ggtgtgaacg agattgtaga gggcgcttta aagcagatca agcttcgcaa
    80881 aaagcgcagc ctcaggcgag tgattaacgc cactggaatt gtgctccaca ccaatctggg
    80941 aagggcaaat ctgtctgata ctgccattga gggagtctgc gaggcggccg cccactattc
    81001 gactctggag tacgacctga aaaagggagc cagaggttcc cgccacagcc atgtggagga
    81061 gattatcaag caggtgacgg gcgcggaggc cgccatggta gtgaacaaca acgcggcggc
    81121 taccatgctg tgtctttctg ccatggccag aggaaaagaa gtgattgtgt caagaggaga
    81181 gctggtggag atcggcggat ccttccgcat tcctgagatt atggaggaga gcggcgcaat
    81241 tttaagagat attggaacga ccaacaagac aaaggtttcc gactatgtga acgcctatga
    81301 ggaaggcgtc acaggcgcgc ttttaaaggt tcacaccagc aattacaaga ttatcggttt
    81361 tactcaggag actacggttt ccgagctttc tgagctggga aaacagtgga atctgccggt
    81421 gatctatgat ctgggaagcg gcctgatgaa cgatctgtct gatttcggtg tggacgagcc
    81481 tacggtgcag agtgcgcttc gggacggcgc cgacgtggtg cttttcagcg gagataagct
    81541 tttgggaggc cctcagggag gcattatcat aggaaagaag gagtttattg acaggatgaa
    81601 ggcccatcct ttagccaggg cgttccgggt agacaaaatg acgctttctg ccatggaggc
    81661 caccttcttt gagtatctgg atcggacgac ctgcaggaaa aatattccga ttctccggat
    81721 gcttaccatg actgccgatg agcttcacaa gaaggcggag gccttgaaag ctctgcttga
    81781 gaaagagaca gaaggctttc tgttccaggt ggaggcctgc caggatcagg taggcggcgg
    81841 ttctgcgcct ggcgtaatga ttcccggata cgccgtttct gtcagaagcg gatccatcac
    81901 agaggctaag attgaaagat gccttagaaa ggcggagctt cctgtgatcg cccatgtgtt
    81961 ccgcgacgcg gtctatctga acgtgcggac cattgaggag gatgaatatc ctctgattgc
    82021 aaaagccctt ggcggcgcag agaattgtga tagagaggaa cagtaatcgt atgcagaatg
    82081 taattgtggg aaccgcaggc catgtggatc acggaaaaac atgtctgatc aaggccctca
    82141 gcggaattga cacggatcgc ctgaaggaag agaagaagag gggaattacc attgagctgg
    82201 gatttgccaa tctcattgac acagacggcg ttcatatcgg cattatcgac gtgccgggcc
    82261 atgagaaatt tgtcaaaaat atgctggccg gaatcggcgg catcgatctg gtactgttag
    82321 tcatcgccct ggacgaggga gttatgcccc agacggtgga gcattttgag attctgaaaa
    82381 tgcttcagat ccgccagggc atcgtggtcc tcaccaagtc tgacacagta gacagcgact
    82441 gggcagatat ggtggaggag gatgtgagag agctgatcaa gggaagcttt ctggagcagg
    82501 cggaactgat ccgcgtatcc tcctacactg gggagaatat tgacgtttta agacagaaga
    82561 ttgtcactat ggcaaagcag gctggcaaac ggagagagga gaaggagctg ttccggcttc
    82621 ccattgaccg cgtattcacc atggaaggat ttggaactgt cgtaacagga acgctcatag
    82681 agggaatgtg cgaggccgga gaagaggtga tggtatatcc ccaggagcgc ctgttaaaga
    82741 ttcgaggcgt tcagagccac ggccagaagg aggaaaaggc ctgtgcaggc cagagaacgg
    82801 ctatcaacct ggctggaatc aagaaggagg agctgagccg cggcgaggtg ctggcttatc
    82861 caggctctct ggtgaacagc actatggtgg acgccacgct gcgccttttc gactctaccc
    82921 agaggaagct gaaaaacgga gacagagtcc atttaagcta cggatccgcc caggccatcg
    82981 gaaaagtaat tttgttagac tgcgacgtgg tggaggcagg ccaggaggct ctggtgcagc
    83041 ttcggtttga cgatccgatc tgcgtgaaga gaaacgacaa atttattatc cgtttctact
    83101 ctccagtgga gaccttcgga ggcggtacgg tgttaaatcc ggctgctgac aagcacaaga
    83161 gaggccagga ggatgtcatc gagtccctga agctgaaaaa gacaggcacg gatatggaga
    83221 ttctggagca gatggtcaac gaggagagcc gccggttccc tgaggcggag gatctggccg
    83281 cctggatgga cctgacagtc tccgaggcag aacagatgct ggatactctg aggaataaga
    83341 agaaaattct tcacttaaac gacggaagct tcgtgggaaa ggcctactgg gagaaggttt
    83401 ctgaactggc caaccaggtg ctggcccatt tccaccggga aaaccccatt gtggagggaa
    83461 tggaccgcga ggagctaaag agccgtctgg cagagaggat gcacttaaag agcggaaaga
    83521 aggcagaggc cctgatagcg gagctggaga agaggaaggt tatcactatc cagggaagcg
    83581 tcgtatcggt ggcaggattt acagtcagct actccgatga ggcctcccag atgatgacag
    83641 acatggagaa tatctacaaa aaggcgggaa tcgaggttcc gtctaccgat gagctggtag
    83701 gagcctataa ggacagaaag caggccagac aggtgctctc cgagctgacg aagaagggaa
    83761 ttctcgtgaa ggccggaacc ggcgtgctga tgcacaagga acactgggat cgggcgctaa
    83821 atatcctgag agagcatttg gcggccaatc cgcagattac cctgggagag ttcagggatc
    83881 tgcttggaac ctccagaaaa tacgctgtga tgcttctgga aacttatgat cagatgaaga
    83941 tcacaaaaaa gacaggagat gtcagagttc ctggaggaaa ataaacagat tgcaggggtg
    84001 ctgtaccctg acaataaata tttattttta caaaaggggg ataaaaaaat gaacaacagt
    84061 agcttgacaa caaggctcat tctgggagca gtcctgggag cggcggctgc agcgctggct
    84121 tttctgggaa atccggctaa tatggcgctg tgcattgcct gctttatccg tgatacagca
    84181 ggatccatga aaatgcattc agcggcagta gtgcagtatt tcagacctga ggtagtagga
    84241 attgtatgcg gagcctttct gatttccgta gctacaaagg aataccgctc gacctcaggc
    84301 tcttcaccaa tgatccgctt ccttttgggt gtgattatga tgatcggttc cctggtattt
    84361 ttaggatgcc cgcttcgcct tctgctcaga ttgtcagcag gagatttgaa cgcggtagta
    84421 gcacttccgg gctttgttct gggaattttt acaggaaccc ttgctttaaa gcgcggcttt
    84481 acattgggaa gagcttatcc gacaaaaaat tcaagcggat ttgttctgcc gggacttctt
    84541 gtatttctgt ttgtgctgag cctgaccacc acgctgtttg tatccagcga gtccggacca
    84601 ggaagcaagc acgcgcctat agcggcagct ttaattgcag gacttgtatt tggagcagta
    84661 gcgcagaaga gccgtacctg ctttgcagga ggattccgcg atgttatttt gatgcggaat
    84721 tttgacctgt taagcgtgct tggtggactg tttgttgtta tgctggtatt taatctggca
    84781 acaggcgggt tcaagctgtc ctttgcagga cagccggtag ctcattctca gcatatctgg
    84841 aacttccttg gtatgtatgt agtaggtttt gcagctgttc tggctggagg ctgccctctg
    84901 agacagctgg ttctggctgg tcagggttct tcagattccg cggtcacatt tctgggactg
    84961 ctggtaggcg ccgctttctg ccacaatttt ggtctggcag cttcagcagc ggctgccgca
    85021 actgagactg cagaggcagt agccggaggt cctggcccag ccggaaaggc tgcagttctg
    85081 atttgtattg cagtattatt cttaattgga tttttacctt ccagagaaaa aaagtaaatg
    85141 aaacaggcat tcaggaaaca aataggcaga tcgaaaaaac agaaaagagg acagaattat
    85201 gtatgaggta gacgccagag gactttcatg tccggagcca gttatgctga ctgctgatgc
    85261 tattaaaaag catggaaatg agacaatcaa agtgcttgtc agtgaagtcc acacaagaca
    85321 gaacgtggaa aaatatgcga aaagccacgg gaaaagtgtt tctgtaacgg aaaaaggaac
    85381 agagtttgaa ctgacaatta agtaacagga gaaaactgcc agctggcgtg aaattgtcgg
    85441 ctggccgctt ttatggaaag agaacaatga gaaaaaaaga acctacttta attattacgt
    85501 ttcacaccac agcagatgct attgccctgg aaaaggcctg cagggaaacg ggacgtccgg
    85561 gacgcatgat ccctgtacca agagaactgt ctgctggctg cggcctggca tggtgtacca
    85621 gcccggatca cgcagaagat tttaaaagct ttctggagga aaaaggtctg gtgtgggaag
    85681 cgtttgagga aattctgtac tagccgcagt ggaaaggaag gcagaaaaga tgatttattt
    85741 tgacaatgcg gccacaacca tgacaaaacc gaagcaggta gcagaggctg tggcaatggc
    85801 tttgacaaat tttggcaatt cgggccgcgg agccagcgag gcctccatgg acgcctcccg
    85861 tattattttc agtaccagag agaagctgtc ccgcctgttt cacggaggag atccaaagca
    85921 gacaatcttc acctgcaacg ccacagaaag tctgaacatc gctattaacg gcctgattgg
    85981 accgggggac catgtgatta ccacagttct cgagcacaat tctgtgctca gacctctgtt
    86041 tcacctggca gaacagggca cggatctttc ctttgtcacc tgtaacaaca agggaaggct
    86101 gaaatacgag gagtttgaaa agcatcttaa aaagaataca aaggcagtgg tgtgtaccca
    86161 cgcctctaac gtaacgggaa atgtagtaga tttaaaacag attggagaat tctgcagaaa
    86221 gcacggcctt ctctttatcg ccgatatttc ccagacagcg ggagcgtacc ctgtggatat
    86281 ggaggtattc caggctgatg tgctctgttt taccggccac aaaggtctgt tcggccctca
    86341 gggaacagga ggactctgcg tgagagaagg cgtggatatc gcccccttta agagaggcgg
    86401 aagcggcgtc cacagcttct taaaagaaca tccggctgag atgccggtac gcctggaggc
    86461 gggaacttta aacggacacg gaatcgcggg actgagcgct gctcttgatt ttattgagga
    86521 gaccggtgtg gagaatattc acagccgtga aaacgccctg atgctgcagt tctatgaggg
    86581 tgtcaaggat attccgggag tcattgtcta cggtgacttt gagagtagcc tgagccggtt
    86641 cagaaggaca gcagtagtat ctttgaacat tggagattat gattcttcca gagtcagcga
    86701 tgagctggaa acggtctacg gcattgccac aaggccagga gctcactgcg cccctctgat
    86761 gcaccagtct ctgggaaccg ttgagcaggg aatcgtcaga ttttcttttt cctggttcaa
    86821 tacagaagaa gaggtggagg cggcagtccg ggcagtgaag gagctggcag aggacgaata
    86881 gaaagaagaa tatttcaaaa aagagagaag aaaagagaga ggccccagct gagaattacg
    86941 gagaaacgac ggcagcctgg cgcagaagaa agattcatat cttctgcgcc aggctgtttt
    87001 gtatgttcag atgcggttta tgggttccgg catagcaggc agaaagaaac cctgaacctt
    87061 ccggctcagg gcttcctctt gattcgtatt tagtttttat ctctctactt tagtttgtca
    87121 tgacatgatc ttctgtcata gtctttgtgt agtttggatc aatgccgtac ttcttcatga
    87181 agatgttatg taagataatc tgtaagaagt acagagctat gatacctgcc ggaatcatga
    87241 taaccgggga gatgcggaag aagccataga gtacatacag gacagcgata actgcgccga
    87301 ctgtacatgt gtaaggaatc tgtgttccta cgtggtcaat atggtctgca cctgagaaca
    87361 gggaagccat aaccgtcgta tcagatactg gtgagcagtg gtctccgaag atagcaccgg
    87421 ataatacagc gccgcacata ccgatggaga actcagcatc acctgtaaca gcgtagccta
    87481 actgaatagc cagtggagtc atgatagcca tggttcccca ggaagtacca gttgcgaaag
    87541 cgattaacat ggagcagaga agaaccagaa caggaaggaa tcctgtcggg atagcaccgc
    87601 caacgtagtg agctacgaag tcaccaagtc ccatgctctt tgtaacgtct gctaaggacc
    87661 atgcaagaac caagatagca cctgtcagag ccatcagctt gaagccgtct acgatagtag
    87721 tcatggtctc gtcgaatgtc atgattctgg aagcaagggc gattacgata cctgtaactg
    87781 ccattgcgaa ggagccccag taaagagcaa gctgtacgtc acatacattg aagatatcca
    87841 tgataccaga acctgtacga tccgggctgg tccatcctgt gtagatgata ccgaagatga
    87901 taacagcaaa agtaacaacg atcggaagta cgaaggagcg gatcatcggc tttgtctgct
    87961 tagcctctcc aagttcgctt cctacgtcaa gcattggctt agcgccggaa cggttgaact
    88021 ctccagtctg aaggcagcgt gcctcagcct ttaacattgg gccgtagtcg cggcctgtat
    88081 acatcagcat tcccacgaag agaagtgtga aaatagagta catgttgaat ggaagagtct
    88141 taatgtaagc tgctacaggt gtgtagcctg tgatgccggc tgcgtcaagt ccctggccga
    88201 tcataccgat ctggtaagca atccagtcgg agatgaaaaa tgctgctgcc ggagctgctg
    88261 tagcatcgag aacgtaggag aatttctcgg aagaaattct gtagtcctta cagatatcac
    88321 ggaatacgtt tccgtcgata gctgctgcca gacagtcgtt tacagaacaa gcaattccaa
    88381 gtccccaggt tccaagacat acggaacggc gttttttgaa gcgcttctta gctgctgcag
    88441 ccagagcgaa gcttccgcct aatttccaga tgaaagagat accaacgccc atgaacagtg
    88501 tgaagagcag cagaacaatg tttccggaca tgtttaccgc aattttgtca agggcaaacg
    88561 cgcaggctgc gaatgggttc cagtgagaca taatcaggga acctgcgaac agtcctgcga
    88621 acattgagat caatacctgt ttggtagcga agcagagaga aatcgcaact acaggcggca
    88681 cgagtgccag aaaaccataa ccagtttcca tacaatattc ctccttttat ggaattgttg
    88741 actaattata aagcaagtgt aatgccagtt cttgtgaaat atgtgtaaat aatttgtgaa
    88801 gagcctaaaa ttttaattaa aaatgctgag gaaacggcgt aaaaaaggga tttaaaggga
    88861 tttgttgttt tttgaatttt tttgagaaaa aacagaaaag aaaaatttta ctaaaattaa
    88921 aatctgtaca aaatgaaaaa tgccggaaga ttgacagaaa gatttggcat tcttcctgtc
    88981 aacctgctgg caaagatggc aaattaacgt catttcagta cagcatcccg gtgaagcgga
    89041 tgtgcggcgt ctaaagattc attttattta atttccggta aagggtccgc aggctgatgc
    89101 ccagatccgc cgcgattttc tttttgccct ccagcgtgtg tccgtaggcg gagagaagat
    89161 agaggatctg tttttcctgg gaatcgggaa gaggagcttc cttctgcttt tcagtgtcag
    89221 ggcattcctc cagacctcgc atatgttccg gcagatcggc cagcgtcagc gtgtcgctgt
    89281 cgcagaggtt ggctgcgtac tccaccacat tttgaagctc tcggatattt ccaggccagg
    89341 agtagtttaa aaaggcctgc tccgcctcag gggaaatcgt ccggagaggg gtggtcattt
    89401 tcgttttcag ccgttccaga tagtttaaac tgatggggat aatatcctct tttctgtccc
    89461 gtagaggcgg cagctttacg ttgataacgc tgattcggta gaagaggtcc tcacggaatt
    89521 tcccctcctt aatcatttcc cgcagatccc ggttggtggc agccacaata cggatgtcaa
    89581 ggtggatttt cttcgtagag cccacccgct ccagctcgta ctcctgaagt acgcgcagaa
    89641 gcttcggctg aacggagaga ggcatttccc ctaactcgtc cagaaacagg gttccgccct
    89701 gggccatctc gatccggccc atttttccgc cctttttcgc tccggtgaag gaaccctcct
    89761 catagccgaa cagctcgctc tcgaacagat tttccggaat actggagcag ttgatcgcca
    89821 caaagggata tttgtttctg cggctctgct cgtggaagga gcgggccacc agctcttttc
    89881 cggttcccgt ctctcctgtg atcaggatgg gcgtagggct gtccgccacc cgcttgatca
    89941 gattctggat atggacaaag gcgcggctgg atccgatgag ccgctcaaag gcgccggatt
    90001 caggaagact ttcataaaat tcattggaca gtctcaccag aatcgagtgg agatgattct
    90061 gagagtaaat ggaacgggtg gtcaccttgg cggtattttc tccaatggaa gccttctttt
    90121 caaacagatc gtttccggag gtgatccggc gggccatgtc ctcgctgaaa atctgccgga
    90181 gactggtgga agacacgttg cagaatttca gcaccttatc agccaggctg ttgtagcgga
    90241 gcacgactcc gttggggtcg gtcaggagaa ggggctgctc gcacagggac atcaggcttt
    90301 ctatcagctt ttccgtgtct gcggctgcgc ttccctcgga aaactgctgg agatactccc
    90361 cgatcagact ggaaagcttg gtgatggcgt ttaagtaaac ctccgtattt tcagaaatcc
    90421 gcttctgccc ttcttttgta aaagaggtaa aggagataac gcccgccacg tcggttccgc
    90481 tgtggataca gcagagaatc tccatagtgg agggacagtg ctcgttgaag cggcagccga
    90541 tgcaggccgg cattttgcca ggctcggtga caaggacgct gccgttgaca attacgtcct
    90601 ggataaaggc atagtgaacg gtgttgcctt ttttctttaa ataggtagga gtacagtaaa
    90661 acagactgct ctgctggtta aaaatagccg cctccacccg gaaagcctct gccgcggctg
    90721 agacgaaatg ctcaatgcct gagcgtacac tttctaattg agtcatgatt ttcctccgat
    90781 atttcagtaa aattctgtat gtaaagtgac aaatgcagca atttgacatt tggattatag
    90841 cataatcaga ggatagtgac aatatagcag gggaaaatgt ggcaaaccat tgacgtttga
    90901 caaaaaaaca gggaaaatat gacaaatttc atgtcacgat agaaatgaaa aaccaggcag
    90961 aaaaaaagga acgcaggtaa aataaaaaaa ataaaaaaca gaattttatt aggaaaaatg
    91021 gacgtttttc caaaacgaaa agagattaaa cgagagcaat ttgtaagatt tctatttttt
    91081 ggcacgcacc ttgctctata atctgtcata aaagcggtgc aggctgacag gggaattcag
    91141 caaactgtac aagcgattta aaaacagcaa atcatttaaa atgaaaatat tttaaggagg
    91201 acaacgatta tgattacaaa gaaggatcca ttaaacctca ctggcaaggt tgcagttgta
    91261 acaggaggaa gctcaggaat cggtttaggc gttgttgaga ttctttccgc ttacggcgca
    91321 aaggtagcta tggtagatat cagcccgaag ggtgaggaga aggctgagga gctccgccag
    91381 gcaggaagag acgttacatt cttcaaatgc gacgttacaa acgaggagca ggttaaggca
    91441 accatcgacg gcgttgtagc aaaatacgga agaatcgatg ttctccacaa caacgcaggc
    91501 gttacagtaa gaaagacaat cgctgacctg acagagaaag agtgggattt cgttctcgat
    91561 gtaggtttaa agggactgtt cctcttctcc aagcacgcta ttccggtaat ggcagctaac
    91621 ggcggcggaa gcatcatcaa cacaggttcc ggctggggct taaagggcgg cgacctagca
    91681 gcagcttact gtgcagttaa gggcggtatc gtaaacgtaa caagagctat ggctatcgac
    91741 cacggcccac agaacatccg tgtaaacagc gtaaacccag gagatacaga tacagcaatg
    91801 cttcgtgacg aaggaaagca gacaggtgct gttaaggaag gcgcttctca gatggatgct
    91861 taccttgcag actgcggtac aagcagaccg cttgcaagaa ttggtatgcc agaggatatc
    91921 gcaaacgcag ttctcttcct tgcaagtgac ttatctagct ggatcacagg tgcagcttta
    91981 gtagttgacg gaggcggaat cgcttaatca ggtctttttt gaaagacaaa gcttagtaga
    92041 caaattggaa aagaggacgc caagcctcct cttttccaga atataaacct gaaattaaag
    92101 gaggaataaa caatgaaagg atatgcaagc catccttaca taccgaactc agttccggaa
    92161 atccaggagg agatgctcca cgaaatcgga atgagctctt tagaggaact tcacaaaaac
    92221 gttccggaga tcttaaaatt aaaagagaat atgaacctgc cgaaggcatt cggttctgag
    92281 tatgagttaa agagacacgt tgagagagtc ctttccaagg atacagactg ccacaagaac
    92341 ttaaacttct taggtgcagg atgctggcag cactacgtac cggctatctg tgatgagatc
    92401 aacggcaagg gcgagttctt aacagcatac ggcggcgagc cttacaacga tgagggccgt
    92461 ttccagtctc tgtttgagta tgccagcatg gtagctgagt tagtagatat ggacgttgta
    92521 aacgtaccta ctatggactg ggctcaggct gcagctacaa ctgtaagaat ggcacagaga
    92581 atcacaaacc gttctgttgt tctcgtttct gagattatcg atccgcagaa gttagcagtt
    92641 atgaagaact acgctgagag cgtaatcaag ttcgagactg ttaaggcaac agctcaggga
    92701 actcttgatt tagaggactt aaaggctaaa ttaaatgata acgtaatcgg tgtttacttt
    92761 gagaacccga actacttagg tattattgag ccaaacggcc aggcaatctc cgatgcagtt
    92821 cacgcagcag gcggattaag cttagtaggt gtagatccga tttccttagg agttctttcc
    92881 acaccgccta catacggcgc tgatatcgta tgcggcgact tacagccact tggaatccat
    92941 atgtactacg gcggcggcca gtccggattc atggctacta cagatgatga gaagttcgtt
    93001 atggagttcc cgtccagact gttcggtatc gctccgacat ctgagccagg cgagtacggc
    93061 ttcggcgacg tagcttacga cagaacttcc ttcggacacc acagagagca tggtaaagag
    93121 tacgttggta cacagtccgc actctgggga attacagcag gcgtttacct ggcaaccatg
    93181 ggcccgaaag gtatggcaga ggttgacgag ttaattatgg caaacgctca gtatgcagct
    93241 aagaagctgg ctgagattcc aggcgttaag gtaaatccat tcggcggagc attcttcaag
    93301 gagtttgtag ttgacttcac agcaacaggc aagacagttg aggagatcaa caaggctctt
    93361 cttgcaaagg gcatcttcgg aggaaaggat ttatccaagg acttcccgaa tcttggacag
    93421 tctgctctgt actgcgtaac agaggttcac atgaaggaag acttagatac actggcagca
    93481 gcaatcgctg aggttatcaa ataggctgcg cggaaaggaa tgatattgtg aaaagaatag
    93541 atagatcatc aaaggtcaga acaaaatttc accaggcaaa atgggatgag ccgatcattt
    93601 acgagttaag caccccaggt gagagaggta ttttagtagg agctcctgag gaagaggtag
    93661 ctaaggaagt agaaggaaca gctgccattc cggagggcat gaagagaagc acaaagttaa
    93721 atcttcctga aatgtcccag agccgtgtgc tccgccacta cgctagactt gctcagcaga
    93781 cattaggcgc tgacgttaac atcgagattg gacagggtac atgtacagtt aagtacagcc
    93841 cgaaggtaaa cgagcagtta tccgcactga tccgcgagta ccatccgtta caggatccgt
    93901 ctacagtaca gggtatgctg cagattttcc acgagacaga taagtatatg tgcgagattt
    93961 ctggaatgga tcacttcaca ttccagcctt ccggcggatc ccagggtatc atgaccatgg
    94021 cttccttaat ccgcgcatat ttcaaggaca agggagagga cagaaacgag atcatcacaa
    94081 ccatctactc ccatccgtct gatgcggcag ctcctgcagt agctggcttc aagatcatct
    94141 acttacagcc agatccaaag acaggtcttc cgacattaga gcagttaaag gcagctgctt
    94201 ccgagaagac agcaggctac atcgtagcta acccggagga tacaggtgtt tacaacagcc
    94261 atgtaaaaga gttcgttgat tacatccact ccatcggcgg tctgtgcgct tacgaccagg
    94321 ctaacgcaaa cggtctctta ggcgtaacaa gagcaagaga cgctggattt gatatgtgct
    94381 tcttcaacct gcacaagaca ttctccacac ctcacggctg cggcggcccg gcttgcggcg
    94441 ctacaggcgt tcagaaggat ctggttaagt tccttccggc tccggttgta gattacgacg
    94501 gagagaagta cttcttaaac tacgacatct gtgcaaatcc aagcgcagtt ggcaaggtaa
    94561 gagagtggta cggagttgct gaggttgtat taaaggcata ctgctggatc agaagcttag
    94621 gcgctgaggg cttataccag gtagctaaga ctgcagtatt aaacaacaac tacatgttca
    94681 agaagctcat ggagcttccg gaagtttccg cttactacca ggatggaaac aaccagagaa
    94741 tcgagcaggc tcgttataca ttagaggcgc tggagaaaga gacaggcatc ggcactctcg
    94801 atatccagag aagaatgatg gacttcggta tgcactactg gacatcccac catccattct
    94861 atctgcctga gccaatgact ctggagccaa cagagacacc atccaagaag gatatcgacg
    94921 agtacatcga gactctgaag tacgtattca aggaggctca tgagaaccca gaggtaatca
    94981 gaacagctcc tcacagaagc gtaactcacc aggttgacga gtccggcatg gatgatccgg
    95041 ctaagtgggc tactacatgg aaggtatacc agagaaagta caacgaggac taatcgtttc
    95101 tttctgaaat gccagaatta gaaactgcat aaatgagata aatgagagta taagagaagt
    95161 gctgctgcag catcgttccc gcgtagccgc gggggcggtc acagcagcat ttttcttctc
    95221 agtcaggaga aattatgata gtattttttt gaaagcctgc cagcagaaaa aatactatca
    95281 taattcctcc cgctgagggc agaaacaaga cagaatacag gaaaggagag ctttaattta
    95341 tgaaaaaatt aggacttctt attaatccgg ttgcaggaat gggcggcagc gttggattaa
    95401 agggaacaga tcatatggta gaggaggcta tccgccgggg agcgaagccg agagccaacg
    95461 acagggtacg ccaggccctg aaggagcttc tggaaattaa aaataagttg gagattgtga
    95521 cctgtcccgg cgacatggga gaggatacgg cgaagtccat gggatttcgc acgacagttc
    95581 tccacacagg gggcaggaga agcttaaagg atctcttcga cagctccaga acagatacga
    95641 tcgtcctctc caaggccatg gaggaggccg gggtggatct tctgctgttc gcaggaggcg
    95701 acggcacggc gagagatatc tacgagggcg tgggaacaga gcttccggcg ctgggaattc
    95761 cggccggagt aaagattcat tccccagtat atgcaaaaaa tcctcagagc gcgggagact
    95821 tagcgaagct ttggctcact ggaaaggtca caaagacggc ggagcaggag gttttagaca
    95881 ttgacgagga gctttaccgc caggagatca tcaatacaag actgtacgga tacctgtctg
    95941 tgccgttaga gcatgtgttt acccagaaca ggaaggctcc gacaccgctt tccgagacag
    96001 cctccatcga gtccattgcc catgagatcg tggagcatat ggaggaggac acctactatc
    96061 tgatcggagc gggaaccact accagaggcg ttatgcagat gctgggactt aaaaatacgc
    96121 tgatcggagt ggatttaatc cggaataagg agctggtggc aaacgacatc tatggagata
    96181 agattctcga ctttattaaa ggaaagaaga cgaaactgat tgtcacggtg acaggcggac
    96241 agggcttttt gttcggacgg ggaaaccagc agattacgcc ggaggttatc cgcgaaatag
    96301 gaaaggaaaa cattatcatt ctggcgacca aggcgaagat tgccgagttc caccatcagc
    96361 cgttcctggt agatacgccg gacgaggagt taaacaaaga gctgtgcggc tattacagag
    96421 tcatcacagc ctacggcgag tttaccatgt gccgtgtcag cgaaagctga ttgattccgg
    96481 acaggaaaac gcaaaacagc agaatagaaa aaatatgcag gcggacaggg cggccggaga
    96541 gagaaatttc tcggtctgcg cgtccgcccc tttgtttcta aggggcagag ggagaataaa
    96601 aacagcataa aaatgcggtg gaactgttta aaagagaata aaaatacaac aagcgccggt
    96661 ttttatacaa aaaagcagtt gactattaaa aaaaagcagg tataataggg agatatgaag
    96721 atagaaccat taaataaata ttcatggctg ttttaagcta aaatggagga ggaattcatt
    96781 atgaaaaaga aaatgttagc attatccatg gcagttctca tggccgcttc cttagcagga
    96841 tgttcttcag gggcaaagga gacagagacc acagcagcag cttccgaggc cggcgctgag
    96901 acagcggcag agagcgaggg agagacagcg gcagaggacg cagaggagga gaagactgca
    96961 gagggcggaa ccctgattat gggtacaaac gctaccttcc cgccatacga gtactacgag
    97021 ggagacgaga ttgtaggaat cgacgtagag attgcccagg ctatcggcga gaagctgggc
    97081 atggaggtaa cggttgagga tatggagttc gacgctctga ttccggctct tgcaagcaat
    97141 aaggtagata ttgtggccgc aggcatgaca gtgactccag agaggcagga gtctgtaaac
    97201 tttacagata cctacgcgac agcagctcag gttattatcg taaagcaggg cagcgacatt
    97261 gcttcctccg aggacctgaa cggaaagatt ctgggcgttc agatgggaac tacaggagac
    97321 agcctggcaa gcgagatcga gggagcgcag gtagagcgtt tcaacaagta tttcgaggct
    97381 atccagtctg tgcttcaggg caagattgac gctgtaatca ttgacagcgc tccggctaag
    97441 gcgtttgcag agaaggatga gaatctggta attttggacg aggcattatc ttccgaggac
    97501 tacgctatgg ctatcaataa ggacaataca gagcttcttg acaaggtgaa cgcagcgatt
    97561 gcagagcttg acgaggaggg aactctggac gagatcgtaa acaagtatat cccggcagaa
    97621 taataacagg gaaagagaac agagattatg tggaatcagt ttgtggatac ctttaccagg
    97681 aattttattg acggtggaaa ctggcattat atcgcagagg ggctgttaaa taccatcaaa
    97741 attacgtttt tcgcggtttt gctgggaatt gtcatcggcc tgattgtggg aaccatccgt
    97801 tcaacctacg ataagacgca caagctaaag gcgctgaatt tcctctgcaa catctatctg
    97861 actgtgatca gaggaacgcc agtcttagtg cagcttttaa ttatctatta cgttattttt
    97921 gccagtgtga gaattgacaa ggtgctggtg gcggtgcttg cctttggaat taactccgga
    97981 gcctatgtgg ctgagatttt ccgaagcgga atcctgtcca tcgacaacgg acagtttgag
    98041 gccggacgaa gcctgggctt taactatccg cagaccatgt ggtacattgt gatgccgcag
    98101 gcatttaaaa atgtgcttcc cgccctgtgc aacgagttta tcgctctttt aaaggagacg
    98161 tccattgccg gatatatcgg tatccaggat ttaaccaagg gcggagatat catcagaagc
    98221 cgtacctaca gcgcatttat gccgcttttg gcagttgcgg ccctctatct gattattgta
    98281 ctgattttta cccagttaat taagattctg gaaaggaggc tgagacagag tgagcactaa
    98341 tcatacagaa cagcccctga tccaggtgaa gcatctggat aagagcttcg gctctctgaa
    98401 ggtattaaaa gatgtgacgg tggatatcta caagggagac gtggtgtgcg taatcggcgc
    98461 gtccggctct ggaaagagta cgtttctgcg ctgtttaaac cgtctggagg agccgacggg
    98521 aggccagatc ttttttgagg gcgtggacat cacagacgct aagacagata tcaacaagca
    98581 ccgtcagaag atgggaatgg tgttccagca gtttaaccta ttcccccata tgacgattat
    98641 ggataacctg accctggctc ccattaagct tcagggaaag aagaaggaag agattgagcc
    98701 agaagccatg aagcttctgg agagagtagg cctggccgat cgggcaaacg cctatcccag
    98761 ccagctgtca ggcggacaga agcagagaat cgccattgtc cgcgctctgt gcatgaagcc
    98821 ggacgtgatg ctcttcgatg agcccacctc tgccctggat ccggagatgg taggcgaggt
    98881 tctgggagtt atgaaggatc tggcggacga gaagatgacc atggtggtgg taacccatga
    98941 gatgggcttt gccagagagg tggctacccg cgtcatgttt atggacggcg gcagctttgt
    99001 ggaggagaac gcgccggagg agttctttgc gaatccgaag aacgagaggc ttaaaacgtt
    99061 cctgagcaag gtgctgtaga gaaggataca aaatagttga tagtttaaaa ttttatttag
    99121 aaaagaagac ctgtttttca gcggctttca gtggagcgtg aaaacagatc ctcttttttg
    99181 ttttctgagt tttctattgt ggcgggcagg cggagctgtt atactctatt tagagataag
    99241 gggtaagaca gaagaggaac tgcatgttta taagaaatga aatagagagg gttatcaaag
    99301 aaaattgtat agaacgatca agatgttttg aatgttcaaa gattatgtat agttcaatta
    99361 ttaagaaaat tgaacagacc tttgtactgc acggcggcga tatccattgg tccaatatgg
    99421 ggcatgggtt taatcctaaa ctgcagtgca aaaccaggga catatcaaaa gacaggatgt
    99481 gggttgcaag actgccgcag atattgcctg aacgtgaaaa atttgtatat gctctatttg
    99541 aagaccgcaa gaattatcag cccaagtact gggtgtacga aatgggaatt ccagaactga
    99601 tttgtatcat tgcaga
//
LOCUS       DBMDUW010000003        78126 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_382_length_78126_cov_4.829529, whole genome shotgun sequence.
ACCESSION   DBMDUW010000003 DBMDUW010000000
VERSION     DBMDUW010000003.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 78126)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 78126)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78126
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_382_length_78126_cov_4.829529"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(709..1188)
                     /locus_tag="ACZPCR_01230"
     CDS             complement(709..1188)
                     /locus_tag="ACZPCR_01230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006782285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229544.1"
                     /translation="MDVFFNVLLVILVIAVVVLAVLYFLGRKMEKRQVEQQSMMEAAK
                     QVVSILVIDKKKLKAKDSGLPKMVTDQVPWYMKRAKFPIVKAKIGPKVTTLIADERVF
                     LQLPVKTEAKVVISGLYITEIKSVRGGIPPLPKKKGFFSRFKKDKSKDKNEGKKSSK"
     gene            1484..5353
                     /gene="rpoB"
                     /locus_tag="ACZPCR_01235"
     CDS             1484..5353
                     /gene="rpoB"
                     /locus_tag="ACZPCR_01235"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006443215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0032549 - ribonucleoside binding [Evidence
                     IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HIR1229545.1"
                     /translation="MEKSRMRPAKAGKGIRMSFSRQKEVLEMPNLIEIQKNSYQWFLD
                     EGLHEVFDDISPIADFAGHLSLEFVDFTLCKDDIKYTIEECKERDATYAAPLKVKVRL
                     CNKDKDEINEHEIFMGDLPLMTDTGSFVINGAERVIVSQLVRSPGIYYGIGHDKIGTE
                     LYSCTVIPNRGAWLEYETDSNDIFYVRVDRTRKVPVTVLIRALGYGTNAEIIDLFGDE
                     LKLEKSFEKDTSDNYQDGLLELYKKIRPGEPLSVDSAESLLNSMFFDPRRYDLAKVGR
                     YKFNKKLHFKNRIAGHTLAEDVVDMSTGEILAEKGTVVDKKKAEEIQNAGVPFVWIAG
                     EKKNHKVLSNMMVDLASYVSFDPEEIGVTELVFYPVLQNILAENDGADEETLKDAIRR
                     NIHELIPKHITKEDIIASINYNMHLEGGIGTPDDIDHLGNRRIRAVGELLQNQYRIGL
                     SRMERVVRERMTTQDMESISPQSLINIKPVTAAVKEFFGSSQLSQFMDQNNPLSELTH
                     KRRLSALGPGGLSRDRAGFEVRDVHYTHYGRMCPIETPEGPNIGLINSLATYARVNQY
                     GFIEAPYRVVDKTDPMNPVVTDEVVYLTADEEDNFVVAQANEPLDEDGHFVHNNVSGR
                     FREETSEFQKKRIDLMDVSPKMVFSVATSMIPFLQNDDANRALMGSNMQRQAVPLLTT
                     EAPAVGTGIEGKAAVDSGVCVLAKNAGVVERSASNEIIVKRDSDGQKDVYRLTKFTRS
                     NQSNCYNQKPIVYKGDHVEAGEVIADGASTCNGEIALGKNPLIGFMTWEGYNYEDAVL
                     LSERLVQEDVYTSVHIEEYEAEARDTKLGPEEITRDVPGVGEDALKDLDERGIIRIGA
                     EVRAGDILVGKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGAYGIIVDAKV
                     FTRENGDELSPGVNETVRIYIAQKRKISVGDKMAGRHGNKGVVSRVLPVEDMPFLPNG
                     RPLDIVLNPLGVPSRMNIGQVLEIHLSLAAKALGFNVSTPIFDGANETDIADTLELAN
                     DYVNSSWEEFEEKYKDKVDEKVMEYLGTHLENRKLWKGVPLSRDGKVRLRDGRTGEYF
                     DSPVTIGHMHYLKLHHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALE
                     AYGASYTLQEILTVKSDDVVGRVKTYEAIIKGENIPEPGIPESFKVLLKELQSLGLDV
                     RVLQEDGSEVELTENIDYGDTDIRSILEGDSREYSQNESFEKMGYQKQEFKEDGELTS
                     VESESFSDDYTDDYENDQDDSYSDDEE"
     gene            5372..9037
                     /gene="rpoC"
                     /locus_tag="ACZPCR_01240"
     CDS             5372..9037
                     /gene="rpoC"
                     /locus_tag="ACZPCR_01240"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HIR1229546.1"
                     /translation="MPETNETYQPLTFDAIKIGLASPEKILEWSHGEVKKPETINYRT
                     LKPEKDGLFCERIFGPSKDWECHCGKYKKIRYKGVICDRCGVEVTKASVRRERVGHIA
                     LAAPVSHIWYFKGIPSRMGLILDISPRTLEKVLYFASYIVLDPGKTSLQFKQVLSEKE
                     YRDAVENFGYGSFRVGMGAEAVQELLRGIDLEKDSEDLRKQLKDATGQKRARIIKRLE
                     VVEAFRNSGNKPEWMIMTVIPVIPPDIRPMVQLDGGRFATSDLNDLYRRIINRNNRLA
                     RLLELGAPDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRALKSLSDMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPELKIYQCGLPKEMAIELFKPFVMKELVAKQYAPNIKN
                     AKKMVERLQPAVWDVLEDVIKEHPVMLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVC
                     TAFNADFDGDQMAVHLPLSVEAQAECRFLLLSPNNLLKPSDGGPVAVPSQDMVLGIYY
                     LTQERPGVKGEGMAFKSVNEAILAYENKEVTLHSKVKVRMTRQMPDGTEKTGIVESTV
                     GRFIFNEIIPQDLGFVDRSIEGNELKLEVDFHVGKKQLKQILEKVINTHGATQTAITL
                     DDIKAIGYKYSTRAAMTVSVSDMTVPASKPKLIADAQATVDTIAKNFRRGLITEEERY
                     KEVIETWKATDDQLTHDLLTGLDAYNNIFMMADSGARGSDKQIKQLAGMRGLMADTTG
                     HTIELPIKSNFREGLDVLEYFISAHGARKGLSDTALRTADSGYLTRRLVDVSQDLIVR
                     EDDCCASRGEIPYMEIKGFTDGQETIESLQERITGRFIAEDIVDPDTGEIVIKANHMC
                     TPKRAAAVMKVLDKLGRNTVKIRTVLTCKSHIGVCAKCYGANMATGQAVQVGEAVGII
                     AAQSIGEPGTQLTMRTFHTGGVAGGDITQGLPRVEELFEARKPKGLAIIAEFGGVATI
                     KDTKKKREIIITDNETGNSKTYLIPYGSRIKIQDGAVLEAGDELTEGSVNPHDILKIK
                     GVRAVQDYMIQEVQRVYRLQGVEINDKHIEMIVRQMLKKIKIEESGDSDVLPGTSMDV
                     LDFNDMNDALIAEGKEPAIGRQVMLGITKASLATDSFLSAASFQETTKVLTEAAINGK
                     VDNLIGLKENVIIGKLIPAGTGMKRYRTIKLSTDGEEQVNESVEEEEILDNEYPESGE
                     LDEAEQIVLNEDDLSEE"
     gene            complement(9290..10228)
                     /gene="cysK"
                     /locus_tag="ACZPCR_01245"
     CDS             complement(9290..10228)
                     /gene="cysK"
                     /locus_tag="ACZPCR_01245"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004845753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HIR1229547.1"
                     /translation="MANIYTSAEQLIGNTPLLELTGLERELNLKARLLAKLEFFNPAG
                     SVKDRVAKSMLDDAAAQGKLTKDTVIIEPTSGNTGIGLASVAAARGLRVIIVMPETMS
                     IERRLLMKAYGAELVLSDGSKGMAGAIKKAEELAAQIPGSIIAGQFTNPANPAAHIAT
                     TGPEIYRDTDGKVDIFVAGAGTGGTVTGVGTYLKSKKPDVKIVAVEPASSPVLSGGQP
                     GPHGIQGIGAGFVPAVLDTSIYDEIIQVSNEDAYAAGRMIGQKEGILVGISSGAAAWA
                     AAELAKRPENEGKTIVVLLPDTGERYLSTPLFADLD"
     gene            10641..11756
                     /locus_tag="ACZPCR_01250"
     CDS             10641..11756
                     /locus_tag="ACZPCR_01250"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007867788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HIR1229548.1"
                     /translation="MANTYESLGMKKVSDTVVVTADALRYRSAPDTSADNVKGTIPGG
                     TRLERIYEGNGWSVVKTGGGEYYVSSSYVKKADGSQNQADAQSQNASENKKESQAQTK
                     ESAGGPGGSAGSEGGETPAVQEIGLDGSLPYAGFSKINSGKAVLYKSTAQNRKNKTIA
                     VNAGHGTSGGSSVKTQCHPDGSPKVTGGTTASGAVMAVAVSGGMTFADGTAEAKVTLQ
                     MAKILKDRLLAEGYDVLMLRDGDDVQLDNVARSVLANRYADCHISLHWDSTSNDKGCF
                     YMSVPNNASYRAMEPVASHWQDHNRLGEALVGGLRDAGNKIFSGGSMEMDLTQTSYST
                     VPSVDIELGDKGSSHSDAVLNQLADGLVMGVNRFFGQ"
     gene            11924..12907
                     /locus_tag="ACZPCR_01255"
     CDS             11924..12907
                     /locus_tag="ACZPCR_01255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003502638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HIR1229549.1"
                     /translation="MNDRNTEVLEQYDMEIFSVRRGRGSWICETDKGLRLLREYKGTT
                     KRLEFEEEVLNILQNSGISKVDQYVRNKEGELQSAAPDGLRYIVKEWFSEDECDIRDE
                     NEVVKAAGQIAKLHRILRGIQLKEEWNLGSILAEPMEAEFRRHNRELRKARAFISRKR
                     GKSDFELCVIGNFAPFLEQALEAQRGLEQMAEEGKEPPHYLCHGELNQHHILMGGKEA
                     AIIEFNRMHLGVQAADLYHFIRKVMEKHSWNPTLGMRLLEAYDRVLPMGAKEREYLYY
                     LFLYPEKYWKQLNFYYNANKAWIPARNVEKLRSLEEQQEVRNRFLGMIRGS"
     gene            13038..14774
                     /locus_tag="ACZPCR_01260"
     CDS             13038..14774
                     /locus_tag="ACZPCR_01260"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003525019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HIR1229550.1"
                     /translation="MKDYKAIYEEWLSNPYFDQETKEELRAIRADEKEIKERFYMDLE
                     FGTAGLRGVIGAGINRMNIYTVRRATQGLADYILEQGGAERGVAIAYDSRRMSPEFSD
                     EAARTLAANGIKAYRFESLRPTPELSFAVRELGCIAGINITASHNPPEYNGYKVYWED
                     GAQFTPPHDKGVTEKVMAITDLSAVRTMSREEAESSGLYVTIGAEIDDKYIAQVKAQV
                     VNQAAIDRMQDQISIVYTPLHGTGNIPARRVMKELGFEHVYVVPEQELPDGNFPTVSY
                     PNPEAEEAFELGLKLAKEKNADLVLATDPDADRLGVYVKDDKSSKYIPLTGNMSGALL
                     CDYVLSQKQANGQIPADGQVVKSIVTTNLVDAVAAHYGAELIEVLTGFKWIGKQILKN
                     EQEGKGTYLFGMEESYGCLIGSYARDKDAISATAALCEAAAYYKEKGMTLWDAMIAMY
                     EKYGYYKDAVQAISLKGIEGLEKIQKIMEYFRNNTPAEFAGSKVISVRDYKADTIRDM
                     ASGEVKPTGLPSSNVLYYDLEDQAWLCVRPSGTEPKIKFYYGVKGTSLADADEKSEKL
                     GQAVQKLVEPML"
     misc_feature    14901..15034
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            15080..15568
                     /gene="rplJ"
                     /locus_tag="ACZPCR_01265"
     CDS             15080..15568
                     /gene="rplJ"
                     /locus_tag="ACZPCR_01265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003502687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HIR1229551.1"
                     /translation="MAKVELKQPIVAEISELLNGAKSAVVVDYRGLTVEQDTQLRKQL
                     REAGVTYKVYKNTMIRFAAKGTEFEALEPNLEGPTALAVSKEDATAPARVLAEFAKKA
                     DKLELKAGVVEGTYYDAKGIQVIATIPSREVLLGKLLGSIQSPIANFARVINQIAEAK
                     EA"
     gene            15698..16072
                     /gene="rplL"
                     /locus_tag="ACZPCR_01270"
     CDS             15698..16072
                     /gene="rplL"
                     /locus_tag="ACZPCR_01270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015515516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HIR1229552.1"
                     /translation="MAKLTTAEFIEAIKELSVLELNELVKACEEEFGVSAAAGVVVAA
                     AGGAGEAAEEKTEFDVELTEVGANKVKVIKVVREATGLGLKEAKEVVDGAPKVVKAGV
                     SKEEAEDLKTKLEAEGAKITLK"
     gene            16252..17040
                     /locus_tag="ACZPCR_01275"
     CDS             16252..17040
                     /locus_tag="ACZPCR_01275"
                     /inference="COORDINATES: protein motif:HMM:NF013077.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HIR1229553.1"
                     /translation="MNVSETIKTRTSLRVYDDRMIADSDLDQILEAAFLAPTAGNQQL
                     YSIIVIKSQETKDKLSKSCDNQPFIAKAPVLLLFLADQQKWFDYYRSKGCMEFAAREE
                     GLSWEEPNESDLLLSIEDTMIAAQNAVLMAESLGIGSCYIGDILENYEYHKELFQLPD
                     HAVPISLLCLGYYKEGHKRVYRKRFDKKYVAFEETYKRLSDEELDHMFAEKASGFVKG
                     PAITADNFAQAFYKRKTGAAFSKEMARSVRAMLKAYEGKQEEER"
     gene            17166..17828
                     /locus_tag="ACZPCR_01280"
     CDS             17166..17828
                     /locus_tag="ACZPCR_01280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008399582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229554.1"
                     /translation="MEKQKLEEQLRQFKEAVSSASCLLIGVGDEWAAGEKRSREELAE
                     AYQALYSLTEGKDYFIITTVTDGLIRESAPDQGRITAPCGNEQWQQCSRACTRDIWEP
                     GEIPDGLCPHCGAPLTGNTIFAEAYIEEGYLPQWKAYQEWLGRTLNRELLAVELGEGF
                     LLPKLIRWPFEKTVFFNKKAHMYRVNETFAQVSEDIGDRSVSVQANSVDFVRMAAACL
                     KN"
     gene            17965..18639
                     /locus_tag="ACZPCR_01285"
     CDS             17965..18639
                     /locus_tag="ACZPCR_01285"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007714990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HIR1229555.1"
                     /translation="MGAISNDWLEPLSAEFKKPYYKKLYETVKHEYETRAVYPDANDI
                     FNAFEFTPLSQVKVVILGQDPYHGYGQAHGLCFSVKPGVDTPPSLVNIYQELHDDLGC
                     YVPNNGYLKKWADQGVMLLNTVLTVRAHQANSHRGIGWEEFTDAAIRALNEQDRPMVF
                     ILWGRPAQTKKAMLTNPKHLILEAPHPSPLSAYRGFFGSRPFSRTNEYLKEHGIEPID
                     WQIENI"
     gene            18654..19496
                     /locus_tag="ACZPCR_01290"
     CDS             18654..19496
                     /locus_tag="ACZPCR_01290"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006773886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HIR1229556.1"
                     /translation="MNFFEILKVLVLGIVEGFTEWLPISSTGHMILVDEIIHLNVSEA
                     FREVFMVVIQLGAILAVVVLYFHKLNPFSPRKTQNQKRATIRLWMKIVVACIPAAVIG
                     LPFDNLLDKLMNGYVVSAMLILYGVFFILLENRNRGVKFRIQRVTQISFQTAAVIGLF
                     QVLAMVPGTSRSGATILGAMLLGCSRGAAAEFSFFLGIPVMFGASLLKIVKFMLEGAS
                     FQMYEIFYLIFGMAVAFGVSVYSIKFLMEYVKQHDFKFFGYYRIVLGIIVLSYFGISA
                     LVGA"
     gene            19724..20500
                     /locus_tag="ACZPCR_01295"
     CDS             19724..20500
                     /locus_tag="ACZPCR_01295"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003502709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HIR1229557.1"
                     /translation="MKRFRRQTGILFLIVMVDLLLALNLARLAGGERKVCVSEGESAL
                     PVSEAGDGTLERGTGNGGRTGGGGEEPGEENRFLALTFDDGPHPVCTKELLDGLRERN
                     VKASFFLLGENIPGNEQLIRQMKEDGHLIGTHCYRHVDLTKEDAETAISMIRKTNREI
                     EAVTGEEPVYIRPPYGKWNGQLEDALDMTPVLWDIDTLDWKSQNSGKVLRSIERNAGK
                     HQIVLMHDIFPTTVDAALAAIDTLGEQGYTFVTVDELLID"
     gene            20530..21855
                     /locus_tag="ACZPCR_01300"
     CDS             20530..21855
                     /locus_tag="ACZPCR_01300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002601707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HIR1229558.1"
                     /translation="MDLFDYMRSNTMEKEAPLASRLRPSTLDEVVGQKHIIGKDKLLY
                     RAIKADKLGSIIFYGPPGTGKTTLAKVIANTTSARFTQINATVAGKKDMEEVVKEAKD
                     ALGMYGQKTILFVDEIHRFNKSQQDYLLPFVEDGTLLLIGATTENPYFEVNGALISRS
                     RIFELKQLEKDDIKELLRRAVTDSEKGMGMYQAVLEPEAEEFLADMANGDARAALNAV
                     ELGILTTERAEDGLIHIDLDVAQECIQKRAVRYDKGGDNHYDTISAFIKSMRGSDPDA
                     AVYYLARMLYAGEDIKFIARRIMICASEDVGNADPMALTVAVSASLAVERVGMPEAQI
                     ILSNAASYVACAPKSNSAVNAINAAMKAVKTQTLMPVPPHLQDRHYSGAAALGRGLDY
                     KYAHDYPNHYVKQQYLPDGMEGAVFYEPSDNGYEKEIKARLAFLRGSEE"
     gene            22110..22712
                     /locus_tag="ACZPCR_01305"
     CDS             22110..22712
                     /locus_tag="ACZPCR_01305"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1229559.1"
                     /translation="MKETELVKRLMAGDREAFDALYECYKDQAFRTAWFLAGNRADAE
                     DIVQDTFVKVYVNIGQLKNAEGFKSWFYRILTRTAWKQSDSRKREFPDEEILIHADIA
                     SEASEDGNPEQIFKKEERQRLRAIVDGLDEKYRTTLILYYYSECSTKTIASIMGCLEG
                     TVKSRLFSARRKVKMELMREMKKEGAVYEQEGRRSNQGIV"
     gene            22672..23511
                     /locus_tag="ACZPCR_01310"
     CDS             22672..23511
                     /locus_tag="ACZPCR_01310"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229560.1"
                     /translation="MSRKEDEAIRELFKGEAERMAAPDSLKTRIDREIDRIENERIEK
                     RKGSEKEAVIMKFQKRKVALAAAVIVAIGSITCYATGKMTGLMVGSSHLTEVSEYSGL
                     DTAEEKAGFETGMPETFSNGYAFKNVNTGDGQAVDAEGNGIPGTQYTDIFMTYEKDGS
                     EITASIMPELKEESAEEAGDAEAKTPEAAEIREIGGITVSYYETTMKVVPPDYELTEQ
                     DKKDMENSNFTISYGSDQVYVQKVRSVDWKADGKAYNFLDMEGTVDAETLFSMAQDVI
                     QGK"
     gene            complement(23888..24103)
                     /locus_tag="ACZPCR_01315"
     CDS             complement(23888..24103)
                     /locus_tag="ACZPCR_01315"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229561.1"
                     /translation="MQFRAPMRKINLASDRFNFSSYVPFSIDNERAGLCIYGLRPDGI
                     QIIDRILLLCIRRGRRASCQKTEKSDL"
     gene            24143..24550
                     /locus_tag="ACZPCR_01320"
     CDS             24143..24550
                     /locus_tag="ACZPCR_01320"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229562.1"
                     /translation="MKPYQTAETSEDGTSLIVSSGGDNFTVEVPLDKAPSLEQFFEGV
                     WDTIHSSEIECIETAKQGNRTSYTIVYSSDYCKSKGNDTEIGSSVLQSKILELELMPD
                     ESIKAVKLNTAGYVSGLDASETPVSQKTELYFN"
     gene            24858..26231
                     /locus_tag="ACZPCR_01325"
     CDS             24858..26231
                     /locus_tag="ACZPCR_01325"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006773855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1229563.1"
                     /translation="MNKQNEPETNAITVRDVTKIYRLYDKPIDRLKESLSVTHKNYHK
                     DFYALQNLSFNVKKGETVGIIGTNGSGKSTILKIITGVLTPTSGEVQVDGKISALLEL
                     GAGFNQDYTGIENIYMNGTMMGFSKKEMDEKLPDILEFADIGDFVYQPVKTYSSGMFV
                     RLAFALSINVEPEILIVDEALSVGDVFFQSKCYRRMDELRKNGTTIVMVTHDMGSVIK
                     YCDKVVLLNRGEFVAEGPAGKMVDLYKKILAGQLDSLNEELAQMNDFSGEGISGSGKD
                     GQEILSAAERQNESGQKPGLMKDKITINGNRTEYGDGRAEIIDLGLCDERGNLTNLLL
                     KGEMFTIKEKIRFNTEIQAPIFTYTIKDKKGTDLSGTNTMFEGTDVKPVKKGDVYEVS
                     FTQKMTLQGGEYLLSMSCTGFENGEHVVYHRLYDVANITVISNKNTVGVYDMESQVET
                     KLTRAEE"
     gene            26244..27011
                     /locus_tag="ACZPCR_01330"
     CDS             26244..27011
                     /locus_tag="ACZPCR_01330"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HIR1229564.1"
                     /translation="MKDLNKKLISLIREYGDDRTAALNSCVDLDCFMALSPLRENLLE
                     WYEFQADGELLQVGADYGALTGLFKRRVKAVTVWDESEEQLDIVRERFPDTSEGAPVS
                     CVGGPLRELLQAGKRYDYVVCAGGFQEPEDQWAEILRDLAKPGGTVTAAVCNRFGLKY
                     LAGGKRDQVSLTRNRLSALFPGCAFYYPMPDYRVPTVIYSDRCLPSKGELAGIHTLYD
                     FPEYPSVDVGAEFEAACENGQFANFADSFLIIWKKGE"
     gene            27015..30245
                     /locus_tag="ACZPCR_01335"
     CDS             27015..30245
                     /locus_tag="ACZPCR_01335"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006778510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HIR1229565.1"
                     /translation="MAETIYVKYNGTRRKDFQIKTAIRLEQGEKTVDKTALCPEGEAH
                     IRSFEEKYRLLSEESGRLTFLKPEIRDGGRTARFPFLTGDTLSKRLGEAVSPAAGEAQ
                     EDRRERVKQAVKEALDTAVSCRLEYVSEFNVTPEFLEVFGQPAAGEKAEISSFEEQKK
                     AFEEAFGEQETSFRTANADALFDNVMMCRNPEYEEGGEALEEIPIALDYEWVFPFPVP
                     VSFLKYRVLFYFYEDHRPMLADLFPERSEFLTEFSLDAKLFPVCEAMERSFQSYVHGE
                     NQRILQDNYYVSTKTMKELRQAEQEMERVKDRLSQLKAENAEKDIALRKAQEVQRLTN
                     NHVANLETMIGDLRREIGEMGKTLSYLNRHEALIFKARRKAGQAFNRAVPKGTVKRKK
                     LGYVKNTVLHPASSLKLYTTDEGKNRIKGHFEIGDEYLTYGKLVFPKEEHPMVSIVIP
                     VYNQIHYTYLCLASILEHTKDVSYEVIIADDVSTDATEHLSEFAENLVIRRNKTNQGF
                     LRNCNQAAEAARGKYVMFLNNDTQVTEGWLSSLVRLIESDGTIGMVGSKLVYPDGRLQ
                     EAGGIIWSDGSGWNYGRLDDPDKAEYNYVKDVDYISGAAILLSVKLWKQIGGFDERFA
                     PAYCEDSDLAFEVRKAGYRVVYQPLSKVIHFEGVSNGTDVNGSGLKRYQVENSEKLKE
                     KWAEEFKKQCVNTGNPNPFRARERSQGKKIILVVDHYVPTFDRDAGSKTTFQYLKMFL
                     KKGYVVKFLGDNYLHEEPYSTTLQQMGIEILYGQEYVTGIWDWLDKNGNEITAAYLNR
                     PHIATKYVDYIAEHTNMKIIFYGHDLHFLREFREYELTGDPAKKRDSDYWKSIEFTLM
                     HKAAVSYYPSEVEIEAIHEIDDTVKAKAITAYVYEDFLNNLNLDFEKREGLLFVGGFA
                     HPPNADAVLWFAREVFPLIREKLSVNFYIVGSKVTEEIKALEQPGNGIVVKGFVSEEE
                     LSELYRTCRLVVVPLRYGAGVKGKVVEAIYNGAPIVTTSVGSEGIPGVEDVLLVEDQP
                     EAFADTVVKTYSDTEKLRELAEKTQSYIRDHFSIDAAWEVIREDFE"
     gene            30245..30997
                     /locus_tag="ACZPCR_01340"
     CDS             30245..30997
                     /locus_tag="ACZPCR_01340"
                     /inference="COORDINATES: protein motif:HMM:NF017655.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraX family protein"
                     /protein_id="HIR1229566.1"
                     /translation="MTDQRNNHLIGNGLSREAVKFIAILTMTGNHAAAALLPPGLPRS
                     LLVNIGYFTAAVMCFFLAEGFRYTSSKRRYGERLLFGAVLSQLPFFLVFRLMTFNMMF
                     TLLLCFLLLVVRTDDRFAGKRLVLGILIVFASGLCDWPVMAPLFTLLFWNAGEDWEAR
                     KKACWYVVILYAVFTFVSVCGLLLSPVEALIHTVLSSAGPAAACLTILFLYNGKETNR
                     GGRAGKAQKWFFYLYYPAHLLVIGLIKMAMVL"
     gene            31179..32552
                     /locus_tag="ACZPCR_01345"
     CDS             31179..32552
                     /locus_tag="ACZPCR_01345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HIR1229567.1"
                     /translation="MIKTYVLDTNVLIQAPDAIERFEEHRVVLPLAVLEELDHLKNAD
                     GEKGANARAAIRLLERLRQNGDLTEGVELPSGGRLNIEKNFINEVLPEDLPEERMDNR
                     ILKVCQGLSRTEKGQVILVTKDLLLRIKAQILGVRAEDFISEQVRADQEQYRGRAEAY
                     VPEDSFKEFKKKGIPVSEAYQTDEKGNRIKLELFENEFLILRNELNPDKTQLGRVENG
                     KIKKLEYRKQKPYGITPRSAGQCFLQEALMQPAASAPLVIVKGMAGTSKTFYALAVGL
                     EKLLNHPNGEYRRMLICRPNAQFDDDIGFLPGDEQEKISPLLRPVMDNLEQLIDSDEA
                     DRYDDEKELKGKIEEIFDRGLIQAEALNFIRGRSIVKTYLVIDEAQNMTPSQAKGIIT
                     RAGKDTKVILLGDPNQIDRPFLDERTNGLSYASEHMKGSPLCWQITMDASECERSLLA
                     MDAARRM"
     gene            32606..33274
                     /locus_tag="ACZPCR_01350"
     CDS             32606..33274
                     /locus_tag="ACZPCR_01350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007706521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HIR1229568.1"
                     /translation="MEKELTYKEIRKNKEINTLLERGNEVLGSLGYTDHSAAHAAKVA
                     DTAGKILEKLGYSGREAELSRIAGYMHDIGNSVNRCDHAHTGAILGWQILRELGMSLK
                     EAAVVMSAVGNHDEKTGTAVDPISAALILADKTDVRRNRVRNKVKASFDAHDRVNYAA
                     LSSRLVIQKEKKVIQMELELDDSMCSVMDYFEIFLERMLMCRRAAEVLGCRFKLTANG
                     SKLC"
     gene            33486..34379
                     /gene="rfbA"
                     /locus_tag="ACZPCR_01355"
     CDS             33486..34379
                     /gene="rfbA"
                     /locus_tag="ACZPCR_01355"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007594425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HIR1229569.1"
                     /translation="MKGIVLAGGSGTRLYPLTKVTSKQLLPIYDKPMIYYPISVLMSA
                     GIRDILIISTPEDTPRFQELLGDGHQFGIDLSYAVQPSPDGLAQAFIIGEEFIGGDSV
                     AMILGDNIFQGQGLPKRLRAAAAKESGATVFGYYVDDPERFGIVEFDENGKAVSIEEK
                     PEKPKSNYCVTGLYFYDNRVVEFAKSLKPSARGELEITDLNRIYLEKGELDVILLGQG
                     FTWLDTGTHESLVEATNFVKTVETHQHRKIACLEEIAYLNGWISREDVMAAYEVYKKN
                     QYGKYLKDVLDGKYVDKLHHN"
     gene            34434..35456
                     /gene="rfbB"
                     /locus_tag="ACZPCR_01360"
     CDS             34434..35456
                     /gene="rfbB"
                     /locus_tag="ACZPCR_01360"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002568333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HIR1229570.1"
                     /translation="MKIIVTGGAGFIGGNFVHHMVNKYPDYQIVNLDLLTYAGNLETL
                     KPVEGKPNYKFVKGDIADREFIFRLFEEEKPDVVVNFAAESHVDRSITDPESFVRTNV
                     MGTTTLLDACKEYGIKRYHQVSTDEVYGDLPLDRPDLFFTEETPLHTSSPYSSSKAAA
                     DLFVLAYHRTYGLPVTVSRCSNNYGPYHFPEKLIPLMISRALADEELPVYGDGANVRD
                     WLHVSDHCEAIDLIIHKGREGEVYNIGGHNERTNLEVVKTILKALGKPESLIKYVKDR
                     PGHDLRYAIDPTKMETELGWEPKYNFDTGIAQTIQWYLDNQDWWKHIISGEYQNYFEE
                     MYGDRL"
     gene            35456..36301
                     /gene="rfbD"
                     /locus_tag="ACZPCR_01365"
     CDS             35456..36301
                     /gene="rfbD"
                     /locus_tag="ACZPCR_01365"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009267718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HIR1229571.1"
                     /translation="MKVLVTGVKGQLGYDVVNELTKRGHESVGVDIDEMDITDGEACR
                     RVITEAAPDAVIHCAAYTAVDAAEDNEDLCRRVNADGTRNIALVCRDLDIKMMYISTD
                     YVFNGQGTRPWEPDDQREPLSVYGQTKCEGEMAVEELVKKFFIVRIAWVFGVNGKNFI
                     KTMLRLGQERGAVSVVDDQIGSPTYTYDLARLLVDMTESEHYGRYHATNEGLCSWYEF
                     ACEIFKQAGMTDVKVTPVDSSQFPAKAKRPMNSRMDKSKLAANGFTPLPAWQDALSRY
                     LKEIL"
     gene            36387..37739
                     /gene="glmM"
                     /locus_tag="ACZPCR_01370"
     CDS             36387..37739
                     /gene="glmM"
                     /locus_tag="ACZPCR_01370"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002595901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HIR1229572.1"
                     /translation="MGKYFGTDGFRGEANVTLTVEDAYKVGRFLGWYYGKKKPEEKCR
                     VVIGKDTRRSSYMFEYSLVAGLTASGADAYLLHVTTTPSVSYVVRTEEFSCGIMISAS
                     HNPFYDNGIKVINEKGEKLEEEVITEIEKYLDGEMGEIPYAVREQIGRTVDYAAGRNR
                     YIGYLISIATRSFKNKKVGLDCANGSASAIAKNVFDALGAETHVIHNNPDGVNINTNC
                     GSTHIEGLQKYVVENGLDVGFAYDGDADRCLAVDGEGNLVDGDKIMYICGKYMKEQRS
                     LVNNTVVTTIMSNFGLYKALEREGIAFEKTAVGDKYVYENMSQNGHCLGGEQSGHIIF
                     SKHATTGDGILTSLKIMEVMLEKKESLKKLADEVEIYPQVLKNVRVHDKKTAQDDPDV
                     QAEVQKVSDALGDTGRILLRQSGTEPVVRVMVEAETDAICEKYVDQVIDVMKARGHVI
                     "
     gene            37750..38253
                     /gene="greA"
                     /locus_tag="ACZPCR_01375"
     CDS             37750..38253
                     /gene="greA"
                     /locus_tag="ACZPCR_01375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006859632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0070063 - RNA polymerase binding [Evidence
                     IEA];
                     GO_process: GO:0006354 - DNA-templated transcription
                     elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HIR1229573.1"
                     /translation="MREQLTKKDIEKIQEEIDYRKLVVRKEAIEAVKEARAQGDLSEN
                     FEYYAAKKDKNRNESRIRYLENMIKNARVVSDQSKVDEVGLNDTVTLYFEDDEEEDVY
                     RLVTSIRGNSLENKISIESPLGKAIRGCRVGERAYVKINDKAGYYVEIRKIEKTGDDG
                     TDAIRSY"
     gene            38225..39484
                     /locus_tag="ACZPCR_01380"
     CDS             38225..39484
                     /locus_tag="ACZPCR_01380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009532229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HIR1229574.1"
                     /translation="MEQTQSGAIRLPYLLTLLLVTVCMYTGCLPKGLAGALILLMVLG
                     AGLNTLGNTIPVVKTYLGGSVVCILGAAALQAAGVFPQDAYEMMDSFVNEQGFLVFYI
                     SALITGSLFNIDRDLLIRATVKLLPTALISLAAGVLATGVLGFFMGHSFLEGILFIGV
                     PMTSGGMTAGAVPLSGMYASALGADAGEILTRIAPATVLGNCVAIVFGGLANNLGEKR
                     PSLTGNGRLVNDGTRAPERIPMKPSIPQLSKGLIISLAFYALGALCSHFISVVPAYAW
                     MIIAVVIVKGTGILSEELEDAARQWGQFAIHSWTAAALTGIGATLINLKAIMQTMTPF
                     YFFTITASVAVITMTAAFVGRLMGFYPLESAIAAGMCTTNMGGSGNVAVLSSAKRMEL
                     LPFAQIVTRSCGALMLTLGGVLVQMLR"
     gene            complement(40021..40704)
                     /locus_tag="ACZPCR_01385"
     CDS             complement(40021..40704)
                     /locus_tag="ACZPCR_01385"
                     /inference="COORDINATES: protein motif:HMM:NF018604.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HIR1229575.1"
                     /translation="MKPEQGQVSYGLPIHFLMAFCGGFFGSYAVFNRMSVFGNAQTAN
                     LIELIGAVLGHDFPDALLRLGAFLVFVSALVLSVPLERQLHRKAKYLTLAVEAAIATA
                     ISFFPEDMNPIAAVYPIFFSAALQWSIFPGAEDFVAANVFSTNNIKQTFTSLTEYVLE
                     RKSNPERAREKLKKAICFGGTLLSFHCGVISGFLGSRWLGIKSSLLCLIPLMIVWGLL
                     RREDRKKDE"
     gene            complement(40720..41886)
                     /locus_tag="ACZPCR_01390"
     CDS             complement(40720..41886)
                     /locus_tag="ACZPCR_01390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006779696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HIR1229576.1"
                     /translation="MKAVQVKEGIYWVGALDWHIRNFHGYTTNRGATYNAYLIIDEKI
                     TLIDTVKAPFAAEMLERISDVVDPSKIDYIVSNHVEMDHSGALPELLKVCPNATVVTS
                     APNGIKGLTAHYGDYSYQAVKSGDSLNIGSRTLSFISTPMLHWPDNMVVWCPEEKALF
                     SNDAFGQHYCTSCRFDDETDLAVTLFEAKKYYANIVMCYGSQAAGAWKIVKELNPDMI
                     IPGHGVIWRSHTADILDAYESWSSKTPETGALVVFDSMWHSTELMAQAIAEGFSRKQV
                     PVHLVDLKTEHISDILPFVLDCKYIAAGSPTLNNNMMPNMAAFLCYLKGLSPKKREAF
                     AFGSYGWGGQSVAQVEEELVKCGFNICMDKIRIQYVPTKEQLLEIESKVEALVS"
     gene            42144..42515
                     /locus_tag="ACZPCR_01395"
     CDS             42144..42515
                     /locus_tag="ACZPCR_01395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012201897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HIR1229577.1"
                     /translation="MNIVISNSGEIPIYEQIASQIKNAVIAGEVKPGEPLPSLRFLAK
                     ELRVSVISTKRAYEELEREGYITSVPGKGSFAAEINRELLREEQYKRLEEHLNEAVDA
                     ARTAGISLGEMKELLETLYEG"
     gene            42550..43467
                     /locus_tag="ACZPCR_01400"
     CDS             42550..43467
                     /locus_tag="ACZPCR_01400"
                     /inference="COORDINATES: protein motif:HMM:NF012235.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1229578.1"
                     /translation="MDLGENKNWAEQTALSFDAVEKAYGEFCLGPLTLKLPAGCVTGL
                     VGENGAGKTTLMKLALGMVIPDRGTVSCLDFDPVREGKQARKDVGVVFGELQIPGNFT
                     AQMAGDFWQGIYENFDRDCFKRLQERFAIPGNKPIRRFSAGMKAKLALAGAVSHHPRL
                     LILDEPLSSLDPLAKEEAMEMLRELGGEEISILISSHTVADLEKLADYLAFLHSGNLF
                     LFEEKDRLLERYRAVQGTEGALKGLREQNVRLIGMRRGAFGSWAVLDKTSVQSRAVLE
                     SFGILEEPASLEEIVTCLMREEKSGCREA"
     gene            43484..44101
                     /locus_tag="ACZPCR_01405"
     CDS             43484..44101
                     /locus_tag="ACZPCR_01405"
                     /inference="COORDINATES: protein motif:HMM:NF024741.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HIR1229579.1"
                     /translation="MKGLLYKEFKMFECQVKTWAAVLVFLLACAVFAGETGPFIGGMC
                     GFMVISSLSPFTEERRSGSDAYTAALPVSRREIVKARYGFLLLLDTAAAAVFGSCAMA
                     AGWFLGKNWEETAMEVLAVLGISLILQLFLLPAVYWLGEMKARAALLIFVMGAVFLTL
                     GLSAGGLAATEEAIKRSILSALLLSAVLLAPSYLLSASAMEKKEF"
     gene            44350..44709
                     /locus_tag="ACZPCR_01410"
     CDS             44350..44709
                     /locus_tag="ACZPCR_01410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HIR1229580.1"
                     /translation="MAVSDVECCDFYQVHDDVVKAVKEKMPDEDELYDLAEIFKVFGD
                     STRIKILYVLFEQEMCVCDIAQLLNMTQSAISHQLKILKQSRLVKNRREGKAVFYSLA
                     DGHVRSIINQGLEHIEE"
     gene            44742..44960
                     /locus_tag="ACZPCR_01415"
     CDS             44742..44960
                     /locus_tag="ACZPCR_01415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007862163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HIR1229581.1"
                     /translation="MKKKFKLTDLDCANCAAKMEAGIKKIDGVKDATVSFMTQKLTIE
                     ADDERFDEIMKEVAAVCKKVEPDCIINM"
     gene            44980..46854
                     /locus_tag="ACZPCR_01420"
     CDS             44980..46854
                     /locus_tag="ACZPCR_01420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008399423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HIR1229582.1"
                     /translation="MTKKQKTMLARIIAAFLIYIPLFAASHKGAMEGLSAPVNFAVFL
                     VPYLVIGWDIVYKAVRGIVNGQVFDENFLMTIATFGAFGVGEYSEAVAVMLFYQVGEL
                     FQSYAVSRSRQSIADLMDICPEYANLEKDGELVQTDPDDVEIGDIIVIKPGERVPLDG
                     TVISGESMVDTSALTGESVPRRVETGSEIISGCINESGVLRVEVTKEFDDSTVARILE
                     LVENASSKKAQVENFITRFARYYTPAVVAAAALLAVVPPLALGAGFGPWIQRACIFLV
                     ISCPCALVISVPLSFFGGIGAASRNGVLVKGSNYLEALAQMDTIVFDKTGTLTKGEFK
                     VTEIRPSGMSGEELLRLAALAEHYSNHPISLSIRDAYEKAGGRMNLSSIGKNEEISGH
                     GVRTEIDGSVVLAGNGRLMEAERIAYEPCESIGTVVYLARDGVFAGTIVISDTVKEYA
                     AQAIRDLKQAGVKRTVMLTGDRKAVGEAVAEKLGLDEVFTELLPADKVEQVERLLDGQ
                     AEGRKLAFVGDGINDAPVLTRADIGIAMGSMGSDAAIEAADVVLMDDDPARISVVVRI
                     SRKTLSIVKQNIVFALGVKALVLGLGAFGMANMWEAVFADVGVSVIAILNAMRALKTK
                     "
     gene            46942..48738
                     /locus_tag="ACZPCR_01425"
     CDS             46942..48738
                     /locus_tag="ACZPCR_01425"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229583.1"
                     /translation="MGKTEGLEQQETQQADHIWCTSCGQILPKESVYCEFCGSRIEHE
                     LEKASAGGEKQPEKQKSDSAYRTAYRIEYRDEEGGFGFLRRPGWKKAAAAGMMAACGL
                     VLSAVWVSGRQAGEKGQPLLGYIKDNSLFILEENGESREISDICLRDWKNREQLRLPE
                     AVDWIPFYYEEAGALWYPEQVGDGAFSLMSGSGGNARKADSSAVSVQTAGETAVYEKA
                     NSGLYLYAGGRKKKLTAGAASYQLSEKGDYLIWQEEHPDQTTGLYGVSLDKKGQAAEE
                     ELLERDAEFLGASGDLTRILYKKEGELWLLENHSEKKCLAQNVNQVFLSGQEEKTLFF
                     TRQENEGESLYVLSGKQAGNERTERLLDSEFLFLIHEEDGILTYKASGEAGEEIRIAS
                     SEAYAALDCNPEEEISVAVSGDYGWYLASPEPGADQALYRVSLEPEQFGSAEQAAQQA
                     DRFCGQCGGTPFYLSDLYEQTGDLYFGEQAVSYDVKADSVWLEKNRDGEETDVYFLSD
                     YDAQRESGVLTRYSGEDRRAEEIDGSASGYLAVSGELLYFTDYDPARGQGTLKLYEKG
                     KTQEVDSGVWAAYGRNGDEAAFIRKNQAGGLE"
     gene            48810..49472
                     /locus_tag="ACZPCR_01430"
     CDS             48810..49472
                     /locus_tag="ACZPCR_01430"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229584.1"
                     /translation="MAQDRIEKIKLSIGKRAAAFSRAAALKLEIHRLRLEARTLRAEA
                     RQTEKEMRRGLSEASEKSYEAWKEKEDWKTHMEEAFQEAGELEDSINAQREEAARLEE
                     TAEELKSLRRAEKETAAASEAENRAEENQEAEEKTDAEAVWVCPSCGAAYGKAVNYCR
                     LCGMAAKQESKKNPGEKSQEEENQKEEKQEIENQEEENREEGNREEESRTEEKQEPQE
                     RE"
     gene            complement(49567..50910)
                     /locus_tag="ACZPCR_01435"
     CDS             complement(49567..50910)
                     /locus_tag="ACZPCR_01435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008410 - CoA-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0019605 - butyrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="butyryl-CoA:acetate CoA-transferase"
                     /protein_id="HIR1229585.1"
                     /translation="MDYRKMYETKLVSADQAAAVVKSGDWVDYGWCTGTTVAFDAALA
                     KRMPELYDVNFRGGILMWVPEIFKIENPAEHLTWNSWHMGGIERKAIAQGFSFYAPIR
                     YSELPRYYRDSQTPLNVAVFQAAPMDEHGFFNFGPNASHMAAVCEKADTVIVEVNENM
                     PVCLGGFENCVHISNVDMIIEGDNPAIGQMGGGGAASEVDEAVAKLIVEEIPDGACLQ
                     LGIGGMPNAVGSLIAKSDLKDLGVHTEMYVDAFVDIAAAGKITGAHKGIDKGRQVYAF
                     GAGTKKLYDYLNNNPECMSAPVDYTNDIRSISALDNFMSINNAVDVDLFGQVNAESAG
                     VKHISGAGGQLDFVLGAYLSKGGKSFICCSSTFKTKDGQLKSRILPTLNQGSIVTDTR
                     ANIHYLVTEYGKVNLKGLSTWEKCAAIISVAHPDFRDQLIADAEKMNIWRRSNKR"
     gene            51149..52333
                     /locus_tag="ACZPCR_01440"
     CDS             51149..52333
                     /locus_tag="ACZPCR_01440"
                     /EC_number="2.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003502782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003985 - acetyl-CoA C-acetyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HIR1229586.1"
                     /translation="MSKKVVIASACRTAIGSMGGQLSTVPAADMGAVVIKEALNRAGV
                     APEQVDHVYMGCVIQAGLGQNVARQMSIKAGLPIEVPAVTLNVVCGSGLQCVNAAAQM
                     ILAGDADIVVAGGAENMSAAPYALKNARYGYRMGNAPMIDTMVNDALWDAFNNYHMGI
                     TAENICDEWNITREELDEFSVASQHKACEAVQSGRFKDEIVPVEVKKKKETVIVDTDE
                     GPRPGTTMEGLAKLRPAFKPDGGRVTAGNASSINDGAAAVVVMSEEKAKELGIKPMAT
                     WVAGALGGVDPRIMGIGPVAATKKVLAKTGLKVEDFDLIEANEAFAAQSIAVARELGF
                     NKDVLNVNGGAIALGHPVGASGCRILVTLLHEMQKRDAKKGLATLCIGGGMGCATIVE
                     RD"
     gene            52366..53142
                     /locus_tag="ACZPCR_01445"
     CDS             52366..53142
                     /locus_tag="ACZPCR_01445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003502784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="HIR1229587.1"
                     /translation="MGYVDYEQEGHVGIVTINRPKALNALNEEVLKDLETVFDAIDQE
                     TVRAVILTGAGEKSFVAGADIAAMSTMTKEEGEAFGKFGNDIFRKIETFPIPVIAAVN
                     GFALGGGNELSLSCDIRICSENAVFGQPEVGLGITPGFGGTQRLARIIGVGKAKEMLY
                     TARNIKADEAYRLGLVNAVYPQEELMTAARKLAGQIAANAPIAVRNSKKAANDGLQTD
                     MDQAIVIEEKLFGACFETEDQKEGMAAFLEKRKEKQFKNR"
     gene            53183..54019
                     /locus_tag="ACZPCR_01450"
     CDS             53183..54019
                     /locus_tag="ACZPCR_01450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016288901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-CoA dehydrogenase NAD-binding
                     domain-containing protein"
                     /protein_id="HIR1229588.1"
                     /translation="MKIGVIGAGTMGSGIAQAFAQTEGYEVALCDINEEFAANGKKKI
                     AKGFEKRIAKGKMTQEDADKILAKITTGVKDICGDCDLVVEAAIENMEIKKQTFKELD
                     AICKADCIFATNTSSLSITEIGAGARPVVGMHFFNPAPVMKLVEVIAGLNTPKEMVDK
                     VIAISEEIGKTPVQVEEGAGFVVNRILIPMINEAIGIYADGIASVEGIDIAMKLGANH
                     PMGPLALGDLIGLDVCLAIMQVLESETGDPKYRPHPLLRKMVRAGRLGQKTGRGFYDY
                     SK"
     gene            54125..55279
                     /locus_tag="ACZPCR_01455"
     CDS             54125..55279
                     /locus_tag="ACZPCR_01455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HIR1229589.1"
                     /translation="MDFTLSKEHEMARTLFHDFAEKEVKPLAQEVDETEHFPTETVKK
                     MQKLGFMGIPVPKEYGGQGCDPLCYAMCVEELSKVCGTTGVIVSAHTSLCCDPIQTYG
                     TEEQKQKYLVPLAKGEKLGAFGLTEPGAGTDAQGQQTKAVLDGDEWVLNGSKIFITNG
                     KEADIYVIIAVTGVKEDARGRKKKEISAFIVEKGTPGFTFGTKEKKMGIRGSATYELI
                     FTDCRIPKENLLGQKGKGFNIAMHTLDGGRIGIAAQALGLAEGALDRTIEYVKERKQF
                     GRALGQFQNTQFQLADMATKVKAAQLLVYRAAMAKATQKTYSVEAAMAKLYAAEVAME
                     VTTKAVQLHGGYGYIREYDVERMMRDAKITEIYEGTSEVQRMVISGALLK"
     gene            55360..56142
                     /locus_tag="ACZPCR_01460"
     CDS             55360..56142
                     /locus_tag="ACZPCR_01460"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016293394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HIR1229590.1"
                     /translation="MKIIVCIKQVPDTKGGVKFNPDGTLDRGAMLTIMNPDDKAGLEA
                     ALRLKDQYGAEVTVLTMGLPKAEEVLREAMAMGADNGILVTDRVLGGADTWATSQTIA
                     GAIRNLEYDLIITGRQAIDGDTAQVGPQISEHLNIPVISYAQDIKIEGNSVIVERQYD
                     DRYHVLKAQMPCLITALAELNEPRYMTPGGIFDAYKKEITVWGRNDLKDVEDSNLGLK
                     GSPTQIARASDKVRKGAGEQVTLDPAAAADYIVEKLAAKHVI"
     gene            56174..57223
                     /locus_tag="ACZPCR_01465"
     CDS             56174..57223
                     /locus_tag="ACZPCR_01465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016293393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HIR1229591.1"
                     /translation="MNLEAYKGVFVFAQQVDNEISGIAFELIGKGKDLAKDLGTEVTA
                     VLVGSGVKGLADELAEYGADKVIVVDDPELKEYRTEPYTHALASVINEFKPEIFLIGA
                     TAIGRDLGPRVCARIHTGLTADCTQLEIGDFPINPVPGKEQKHNQLLMTRPAFGGNTI
                     ATIACPDFRPQMATVRPGVMQKLPKTAGAKANVVEYNPGFVPNNNYVEIMEVVKAVAD
                     TVDIMDAKILVSGGRGVGSPENFKILEDLAEVIGGTVSCSRAVVDAGWQPKALQVGQT
                     GKTVRPNVYFAIGISGAIQHVAGMEESDIIIAINKDETAPIFDVADYGIVGDLNKVVP
                     LLTEKLKAAKAAQNV"
     gene            complement(57663..58394)
                     /gene="ymfI"
                     /locus_tag="ACZPCR_01470"
     CDS             complement(57663..58394)
                     /gene="ymfI"
                     /locus_tag="ACZPCR_01470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P 5-aminopentanone reductase"
                     /protein_id="HIR1229592.1"
                     /translation="MARKTVLVTGASRGIGKAIAVKFAKKGWNVVISCVKREEQLLQT
                     KKEIESFQVSCLAFLGDMGKMEDCAALFKKIKKQFGGLDVLVNNAGISYIGLLQDMKP
                     EDWDLIVHTNLTSVFNCCRLAVPMMVEKQQGKIINISSVWGICGASCEVAYSATKGGI
                     NAFTKALAKELAPSHIQVNAIACGAIDTEMNHFLDDEELIGLIEEIPAGRLGQAEEVA
                     DLAYHLGYKESYLTGQVIGLDGGWI"
     gene            58647..59567
                     /gene="trxB"
                     /locus_tag="ACZPCR_01475"
     CDS             58647..59567
                     /gene="trxB"
                     /locus_tag="ACZPCR_01475"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HIR1229593.1"
                     /translation="MGKIYDLIIAGSGPAGLAAAIYAKRAELDTLVIEKEMMSGGQIL
                     STYEVDNYPGLPGSSGFDLGMKFREHADRLGAVFTEDCIEKAELLGEIKTLYGQKETY
                     QARTVIIATGASHRKLGIPGEEELLGSGVSYCATCDGAFFKDKTAAVIGGGDVALEDA
                     IFLSRLCRKVHLIHRRDELRGARTLQKQVFESDKIEVHWDTVADAIEGDGRVERLALT
                     NRKTGEKTALETDGVFIAVGIEPESGLFSQMIETDRQGYLAAGEDGVTSVPGVFAAGD
                     VRTKQLRQVLTAASDGANCVTSVERYLAER"
     gene            59582..61111
                     /locus_tag="ACZPCR_01480"
     CDS             59582..61111
                     /locus_tag="ACZPCR_01480"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003502813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HIR1229594.1"
                     /translation="METPFKILACLCSAAVISVTSGFGAQAAINLETDSSVAGVSVAM
                     NNYYAGSLDPENELAEAFSSDETMEQVVKSGKEDAPTVKNPSSSSAYDNVAVSQVSNY
                     VNVRSEASTKGSVEGKIYNNCAATILDTVDGEGGKWYKIQSGSVNGYIKAQYFITGAE
                     AEKKARQVGTTYAKVANTSTLRLREEPSLDSKTLDLLSSDAEYEVIEEKGDFYKVSVD
                     TDLVGYVFKDYVDTRVEFDHAVTNSEEEQKAAEESKRKEEAEKALQELEEAKKEAAKE
                     TTAKETAAKQTAAKETTAKETVKEPETVKPKETEKAKETETSFSGTIEQNPDGSPRET
                     TKAAETKPKETEKEKETTKAPETEKPKETQKPSSDKTSGGPGGSKNPGGSSSGVEKAT
                     RTAVVAYAKQFLGNPYVYGGTSLTKGADCSGFTQAVYAHFGISTGRSSRDQAARGKEI
                     PVSEAQPGDMLFYASGSYINHVAMYIGGGQIIHSSNPKTGICIAPSNYRTPCKAVTFL
                     D"
     gene            complement(61260..61718)
                     /locus_tag="ACZPCR_01485"
     CDS             complement(61260..61718)
                     /locus_tag="ACZPCR_01485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003502815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HIR1229595.1"
                     /translation="MDNTDIKIINILQANCKTSTREIGQQVGLTAPAVAERINRLKDA
                     GVIEGFHAKINDALMGNHICAFVLINVPPKSYESFCRFCEETPSIVEHSHIVGLNNGL
                     LKIRVSDSEELEALLRQMRQFGLSNTSVLLSTYFTQKPFPETEHLKKTED"
     gene            61963..62871
                     /gene="ftcD"
                     /locus_tag="ACZPCR_01490"
     CDS             61963..62871
                     /gene="ftcD"
                     /locus_tag="ACZPCR_01490"
                     /EC_number="2.1.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003502830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030409 - glutamate formimidoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030412 - formimidoyltetrahydrofolate
                     cyclodeaminase activity [Evidence IEA];
                     GO_process: GO:0019556 - L-histidine catabolic process to
                     glutamate and formamide [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate formimidoyltransferase"
                     /protein_id="HIR1229596.1"
                     /translation="MSGKLLECVPNYSEGRDMQKVEQIADCFRGKAGVRLLDYQTDKD
                     HNRCVITAIGEPEALRDAVIESFGKAVQLIDMTKHEGQHPRMGAVDVVPFIPCRNTTL
                     QEADAIAKEVAETVGREFGIPCFLYESSAIAPHRANLASIRKGQFEGMAEKMKDQEMW
                     KPDFGPDTIHPTAGVSAVGARMPLVAFNVNLDTADLEIANQIAKKIRHINGGYRYVKA
                     IGVMLEERHIAQVSMNLTDYTKTAIYRAFEAVKMEARRYGVRAVGTEIVGLLPMQALI
                     DCAEYYMQLENFDSAQVMENRLLEEE"
     gene            62873..63508
                     /locus_tag="ACZPCR_01495"
     CDS             62873..63508
                     /locus_tag="ACZPCR_01495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008399390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HIR1229597.1"
                     /translation="MTELKDLTIEEFAKVTASDAPAPGGGSVAAAAGSLAAALAEMVA
                     NLTIGKEKYAEAENEMRELAEKGQAIREKLIADIQRDSSSFNLYMAALRMPKDTEEEK
                     AARREAMQRGLKEAAVVPLSVAETAAEIFPLAEAAVARGNANAVTDGLVSAMMARTAV
                     LSALLNVKINLNSIKDEAFRADMEKQVKGLEKTASEYEAKILKSSELSPEI"
     gene            63644..65311
                     /locus_tag="ACZPCR_01500"
     CDS             63644..65311
                     /locus_tag="ACZPCR_01500"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008399388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HIR1229598.1"
                     /translation="MKTDIEIAQESTPLHITEIAASLGIDEKYLEQYGKYKAKVDYNL
                     LNEDSRPDGKLILVTAITPTPAGEGKTTTTVGLADGMKKLGKNVVVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIYQGNELRIDPKRV
                     TWRRVVDMNDRQLRNVVDGLGRRVDGVVREDGYDITVASEIMAVLCLAKNVTDLKERL
                     SRIIVGYTYDDEPVTAGDLKAAGAMAALLKDALKPNLVQTLEHTPAFIHGGPFANIAH
                     GCNSIIATRMALKLGDYAITEAGFGADLGAEKFLDIKCRMAELKPSAVVVVATVRALK
                     HHGGVAKADLNNENLEALEKGLPNLLQHVENITKVFGLPCVVAINRFPFDTEAELSLI
                     AEKCRELGVNVALSEVWGKGGDGGTELAQEVLRLCEEPNHFQFCYDSELSIEEKLNAI
                     VTKVYRGAKVVLADSAKKQAKRLTELGFGSCPICMAKTQYSFSDNQKLLGAPRDFTVT
                     VRNLKVSAGAGFIVALTGDIMTMPGLPKVPAAEKIDVDAEGRISGLF"
     gene            65399..66220
                     /locus_tag="ACZPCR_01505"
     CDS             65399..66220
                     /locus_tag="ACZPCR_01505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003502836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HIR1229599.1"
                     /translation="MNFFTPAEIVKNYGAAGKKKAEMPLLKMLILGFLSGMFIALGAA
                     VTNTAGHSIDNVSAVRILSGLLFPGGLTLVVLMGGELFTGNCLMCISVLEKQAKLSGV
                     LKNWAAVYVGNLAGSLFIAFACAKFGQMNYSGGGLAVFTMKLAASKCSLPFENAFVLG
                     VFCNILVCFAVLAAMSAKDTAGKVLGLFFPICFFVVCGFEHSVANMYYIPAGIFASSV
                     PEYAAGALEAGVDLSVLTWGNFFLKNLLPVTLGNIAGGVLTGSFMWLGHVWEKKK"
     gene            complement(66317..66520)
                     /locus_tag="ACZPCR_01510"
     CDS             complement(66317..66520)
                     /locus_tag="ACZPCR_01510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016287363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229600.1"
                     /translation="MEEKKQSGWSNLNGISDDDKTCGLNDMNCLGEDDDSSCGLNDMN
                     CVDGKDDMSCSLNNMNCEEEQNK"
     gene            66796..67458
                     /locus_tag="ACZPCR_01515"
     CDS             66796..67458
                     /locus_tag="ACZPCR_01515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HIR1229601.1"
                     /translation="MSRKLTEQIPSESRLVDAALKENLKTIFERLERPLCLKAVLEPD
                     QRECTEMGAFLKAVAELSPMLEIQLLEKGEDPQADRELDTAHLPVTGLYQEGEYLGAA
                     FCGVPGGKEINSFVSAILNAAGPKKEYDEKILKKLGKLKKKNVIRVCVSLSCHHCQSV
                     VTAGQTLALLSPNVECIMIDARLYPDLVEQYKLSRVPAVLIGEALYMGEKDMEELLAL
                     LR"
     gene            67814..68380
                     /locus_tag="ACZPCR_01520"
     CDS             67814..68380
                     /locus_tag="ACZPCR_01520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate responsive antiterminator"
                     /protein_id="HIR1229602.1"
                     /translation="MEQKLYDTVTDCPVIAAIKDDAGLERCLDSDIQIVFVLYGDIVS
                     IPEIVDRIKKKGKLAMVHADLISGLAGKEIAIDFLKRNTQADGIISTKLSFIKRAKEL
                     GMATVFRFFVIDSMAFDNIQKQYEAACPDFVEILPGIMPKIIAKVAKMVSAPVIAGGL
                     IAEKADIYAAIEAGAISISSTNQNTWFI"
     gene            68396..68995
                     /locus_tag="ACZPCR_01525"
     CDS             68396..68995
                     /locus_tag="ACZPCR_01525"
                     /inference="COORDINATES: protein motif:HMM:NF025636.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HIR1229603.1"
                     /translation="MSDTKRKMAQALKELMAEKPLKRITIQDIVERSHMTRQSFYYHF
                     QDIYEVLELICRYDLVDQIAYREEESFAHWMERLMEIVETNKWFYRKMLQDMDWERVA
                     GYLKPAVEAQIRRLVSGMLTEQETRSLSGGRELLIDFLTVSVIQYIFRYISSRKVQKE
                     QNAASLRELLQICSLLCAKCSSSSENKDEVYIKNRIKTA"
     gene            69091..70587
                     /gene="glpK"
                     /locus_tag="ACZPCR_01530"
     CDS             69091..70587
                     /gene="glpK"
                     /locus_tag="ACZPCR_01530"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019163288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HIR1229604.1"
                     /translation="MAKYVMALDAGTTSNRCILFNEKGEMCSVAQKEFTQYFPKPGWV
                     EHNANEIWSSQLSVAVEAMAQIGANAEDIAAIGITNQRETTIVWDKMTGEPVYNAIVW
                     QCRRTSEYCDSLKEKGLTDKFREKTGLVIDAYFSGTKLKWILDNVPGVRERAEKGELL
                     FGTVETWLIWKLTKGSVHVTDYSNASRTMLFNINTLQWDDEILAELNIPKCMLPEAKP
                     SSCVYGESDPVFFGGPIKIAGAAGDQQSALFGQTCFNPGEAKNTYGTGCFMLMNTGEK
                     PVFSKNGLVTTIAWGLDGKVNYALEGSIFVAGASIQWLRDEMRLIDSSPDSEYMAKKV
                     KDTNGCYVVPAFTGLGAPHWDQYARGTIVGITRGVNKYHIIRATLESLAYQTNDVLQA
                     MQADSGIQLEALKVDGGASANNLLMQIQSDIIQAPVHRPKCVETTAMGAAYLAGLAVG
                     YWASKEDVIKNWAIDRVFAPEIEPEERDKKVKGWNKAVKCSFGWAKED"
     gene            70635..71348
                     /locus_tag="ACZPCR_01535"
     CDS             70635..71348
                     /locus_tag="ACZPCR_01535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006426129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HIR1229605.1"
                     /translation="MLPYIAEFLGTMMLILLGDGVVANVNLNKSGMKGGGSIQITFAW
                     GLAVMVPAFIFGAASGASFNPALTLALAIDGSFDWALVPGYIIAQFAGAFVGAVLVYI
                     LFKEQFDATPDAGSKLGVFCTGPSVENKPLNILSEAIGTFVLVFAIKGLANVPGAAEV
                     GLDKFLVFGIIVSVGMSLGGLTGYAINPARDLGPRIAHAVLPIKGKGDSNWGYALVPV
                     VGPIIGAIAAVLLYGAIPW"
     gene            71722..73161
                     /locus_tag="ACZPCR_01540"
     CDS             71722..73161
                     /locus_tag="ACZPCR_01540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HIR1229606.1"
                     /translation="MYDVIIIGAGVSGCASARELSRYEGKFCVVEKEEDVCCGTSKAN
                     SAIVHAGYDAATGSLMAKLNVEGNQMMEQLSKDLDFHFRRNGSLVLCMHEEELPNLQA
                     LYERGIANGVKELRILSREELKEMEPNVTENAVAALYAPTGGIVCPFGLTIALAENAN
                     MNGVEFKFNTEVKDIQKLEDGTFELHTNNGVLKTRFVVNAAGVYADVFHNMMSEEKIH
                     ITPRRGDYCLLDRTAGDLVDKTVFTLPGKFGKGILVTPTIHGNLLLGPTAIDIDDKEG
                     TNTTREGLDEVIEKAQHSVNNIPMRQVITSFAGLRAHEDHHEFIIKELPDCKGFIDCA
                     GIESPGLSSSPAIGKMVADILKEKAELHEKDNFIATRKGILDPKSLSKEERSRLIKEN
                     PAYGNIICRCETISEGEILDAIHRPLGAKSLDGVKRRTRAGMGRCQAGFCSPRTMDIL
                     ARELNISMYEVTKSGKDSKIVVGTNKDKL"
     gene            73175..74440
                     /locus_tag="ACZPCR_01545"
     CDS             73175..74440
                     /locus_tag="ACZPCR_01545"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HIR1229607.1"
                     /translation="MKSYDIVVIGGGPAGLAAAAAAKRSGIDSILILERDKELGGILN
                     QCIHNGFGLHTFKEELTGPEYAHRFIEQVQELNIEYCLNTMVIDISHEKVVTAMNREE
                     GLFEIQAKAVILAMGCRERSRGALNIPGYRPAGIYSAGTAQRLVNMEGFMPGREVVIL
                     GSGDIGLIMARRMTLEGAKVKVVAELMPYSGGLKRNIVQCLDDFGIPLKLSHTVVEIR
                     GKERLTGITLAQVDGRGKPIPGTEEDYDCDTLLLSVGLIPENELSRGMGVDIEPITSG
                     PSVNESLETNIDGVFACGNVLHVHDLVDYVSEEAAAAGENAAKYVKGILPANSGKEIK
                     LVPTDGVRYTVPKTIDPERMTDELTVRFRVGNVYKNCFVSVYFDGERVVHRKRPVLAP
                     GEMENVKFKKTQLASYPDLKTITLKIEEA"
     gene            74445..74816
                     /locus_tag="ACZPCR_01550"
     CDS             74445..74816
                     /locus_tag="ACZPCR_01550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015561537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1667 domain-containing protein"
                     /protein_id="HIR1229608.1"
                     /translation="MEKRELICIGCPLGCMVTVEMENGEVKSVTGNTCKRGDDYARKE
                     VTNPTRIVTSTVMVKGGSLDMVSVKTKNDIPKGKIFDCVRALKGVCVEAPVHIGDVVV
                     SDICGTGVDVIATKEIEEKRA"
     gene            75054..75797
                     /locus_tag="ACZPCR_01555"
     CDS             75054..75797
                     /locus_tag="ACZPCR_01555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007718323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HIR1229609.1"
                     /translation="MVEICCGSYEDAVSASRGGAERIELNSALALGGLTPPAGCVRLV
                     KERTDLKVISMVRPRGGGFCYTALETEQMFEDAKMLLEYGSDGLAFGFLTERGEIDLE
                     KAGRMVRLIHSYGREAVFHRAFDCTREPEEAVSSLIAVGVDRILTSGLKETAWEGREL
                     LKKLQHEFGGQIEILAGSGVNAENAGALMEWTGISQIHSSCRGWKNDPTTSGENVSYS
                     FAAAPHENDYDAVDESLVKRLVERAGKSV"
     gene            75856..77283
                     /locus_tag="ACZPCR_01560"
     CDS             75856..77283
                     /locus_tag="ACZPCR_01560"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009242406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D-like domain-containing protein"
                     /protein_id="HIR1229610.1"
                     /translation="MTGKKGVILKRLTVGKILLIFLIIYIGFLVLPYVCHKKVPASYQ
                     ESFDVSSFYGSGPGPERTAYIDNNDDALLWRLRLIEEAREEIILSTFDFKSDEAGKDI
                     IAALMQASDRGVQVRVIVDGFNGVLKLTGNKYFKALVSCPGVSIKIYNPISPFRPWDM
                     QARLHDKYLIIDNSMYMLGGRNTMELFLGDYSPEKNVDRELFVYETKQPDENASISQL
                     RRYFETVWALHDSREYVCRKKTSSVEQADKELRERYEYLRETYSEAYTDWDFTALTME
                     TNRISLLSNPIETENKEPLLWYSLQQLMQEADQVTMYTPYIICGKEMYQGLEELKNRG
                     VSVEMITNDVASGANPWGCTDYLNQKEKIWDTGVKVYELMGEYSSHTKAVLLDSRMSL
                     VGSYNFDMRSTYQDTELMLAVDCPELNRIIRQEAERDKAKSKIMGANGEYQYGEGYVP
                     REMSPGKKIFYAIMRVLVIPLRRFL"
     gene            complement(77345..>78126)
                     /locus_tag="ACZPCR_01565"
     CDS             complement(77345..>78126)
                     /locus_tag="ACZPCR_01565"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229611.1"
                     /translation="DDFLNKRGQIMGTKSYFPNNIDENAVPVRISHEEYEELDLLWRT
                     ELGYHYGLPEAAQKYQWWRKMHPDDWDLNYKKYNPLKNAMTPFFNNEIKPDRRKEGEA
                     LKQRAEEERIRRGWPRFIVGENEWKIDNPYAYMALWWGCLYDPENCDEFGNQIWDADI
                     FEHTCEAYEIPTSEVKNTMTAQRPFYVTFYVPSMSDSLFLQASVPAYKVCSFPVKFLC
                     LIPEQHMSGMFKKYGSGAWNVLSHPRAAMPVKHIALSGDAH"
BASE COUNT        21070 a        17079 c        22498 g        17479 t
ORIGIN      
        1 aatgggtgag aaatatggta atgcttgatg cgaatgttat tttgagatat ctgctcaatg
       61 acaatgaaga aattgttggc aaatatgtaa atacagagtc tggcttttat ggtcaggctc
      121 tgtatttatg ataaagtaaa tttctcttcc ccttgcatgg ggatatttta tgcggcttgt
      181 ctggcaagtg tgaagagggt gccattgtcc tgctattttt gaggtacgtt tacctgtata
      241 taattagaaa ctgacgtgat gggaaacctt acagagacaa tctctcctaa gagggcaaaa
      301 actgcttaca cttatgacaa gaatggcgag cttaccagcc aaacagatcc ggcgggaaat
      361 atgatccttt atcaggtaga ttttacagag ccgggcagct taccctccag acaaaaaaat
      421 agccgccaac taccgcgaat agttgacggc tgaccttgtg ttaatgcttt aatattcggg
      481 gtaagctgcc tctgtggctt accttttcct ttactatacc ataccaggca gcaggataca
      541 agggggaata tcacaccctg ccaatctgaa aagtcataga aagctataga attatcctca
      601 aacaggctgc aataaaagag gaagcattac gccaaaacca ggaatttaaa atatccggat
      661 aaaggagtaa tgcttcctct ttcgttgtgc cgaaacggca gaagcttctt atttagaaga
      721 cttttttccc tcgttcttat ccttgctctt atctttctta aacctggaga agaatccttt
      781 tttcttggga aggggcggaa tgccgccgcg cacgcttttg atctctgtga tgtagagacc
      841 gctgatgaca accttagcct ctgtttttac gggaagctgc aggaaaacgc gctcatcagc
      901 aatgagagtc gtaaccttcg gtccgatttt agctttcacg atagggaatt tagcccgctt
      961 catgtaccac ggaacctgat ccgtcaccat ttttggaaga ccggaatcct tggccttcag
     1021 ctttttctta tcaattacta atatggaaac tacctgcttt gcagcctcca tcatggactg
     1081 ctgttcaacc tggcgctttt ccattttccg accaaggaaa tagagcacag ctaaaacaac
     1141 gactgcaatg acaagaatca ccaacagaac attgaaaaag acgtccatag aagtacctcc
     1201 gtaaatttgt ctcacgtccc attatatcat tctgtcctgg aaaaggcaag gaaaacgaac
     1261 aggctgaacg cggtaaaccc atgaataaaa aatggttttc gcctccttct tcctattaaa
     1321 aagaaaattt tctcatcatc tgcttgacat cttgacaagg ccatgatatt atgaaaaatg
     1381 cactattgtg gtgtcgtgcg cctatagcta tatttgaaac ctcatcggga agcgtgcgaa
     1441 acccgccatt aaacatagaa agaaaacagg ggtgaaacgt cgaatggaga aaagcagaat
     1501 gcgtccggcc aaagccggta aaggtatcag aatgagcttc tctaggcaga aggaagttct
     1561 ggaaatgcca aacttaattg aaattcagaa aaactcttac cagtggttcc tcgacgaggg
     1621 cttacatgaa gtgtttgatg atatttcccc gatcgcggac tttgcgggcc atttaagtct
     1681 ggaatttgta gattttacgc tttgtaaaga tgacattaaa tatacaatcg aagaatgcaa
     1741 ggaacgcgac gcgacttacg ctgcgccttt aaaggtgaag gtaaggcttt gcaacaagga
     1801 caaggacgag attaacgaac atgagatttt catgggtgat ctgccgctta tgacagatac
     1861 aggttctttc gtgatcaacg gagcagagcg tgttatcgtc agccagttag tacgttcccc
     1921 tggtatttat tatggtattg gacatgacaa gatcggaacg gagttataca gctgtacggt
     1981 aatcccgaac cgcggtgcat ggctggagta cgagacagat tccaatgata ttttctacgt
     2041 tcgtgtggac agaaccagaa aggttcctgt tacagtcctg atccgtgcct taggatacgg
     2101 aacaaacgca gagatcattg acctgtttgg cgatgagtta aagcttgaga agagctttga
     2161 gaaggatacg tctgacaact atcaggacgg ccttctggaa ttatataaga aaatccgtcc
     2221 aggcgagccg ctgtctgtag acagcgccga gagcctttta aacagcatgt tcttcgatcc
     2281 gagaagatat gacctggcta aggtaggacg ttataaattt aataagaagc ttcactttaa
     2341 gaaccgtatt gccggacaca cgctggctga ggacgtggtt gacatgtcca caggcgagat
     2401 cctggctgag aagggaacgg ttgtagataa gaagaaggca gaggagattc agaacgcagg
     2461 cgttccgttc gtatggattg caggcgagaa gaagaaccac aaggttctct ccaacatgat
     2521 ggtggatctg gcttcctacg tttcctttga cccggaggag atcggggtga cagagttagt
     2581 attctaccct gttcttcaga atattctggc agaaaatgac ggagcggacg aggagacctt
     2641 aaaggacgcc atccgcagaa atatccacga gctgattccg aagcatatca caaaggaaga
     2701 catcatcgct tccatcaact acaatatgca tctggaaggc ggaatcggaa ccccggacga
     2761 tatcgaccat ctgggcaaca gacgtatccg cgccgtggga gagctcttac agaaccagta
     2821 ccgcatcggt ctttccagaa tggagagagt ggttcgcgag agaatgacaa cacaggatat
     2881 ggagagcatt tctcctcagt ccttaatcaa tatcaagccg gtaacggctg cagtgaagga
     2941 gttcttcgga agctcccagc tgtctcagtt catggatcag aacaaccctc tgtccgagct
     3001 gacacacaag agacgtctgt ctgcattagg acctggcggt ctttccagag accgtgccgg
     3061 attcgaggtg cgagacgttc actatacgca ctatggacgt atgtgcccga ttgagacgcc
     3121 tgagggaccg aacatcggtc tgatcaactc cctggctacc tatgcaaggg taaatcagta
     3181 cggctttatc gaggctccgt accgcgtggt agacaagacg gatccgatga atccggtggt
     3241 aacggacgag gttgtttacc tgacagctga cgaggaggat aacttcgtag ttgcacaggc
     3301 gaacgagccg ttagacgagg acggacattt cgttcataat aacgtatccg gacgtttccg
     3361 cgaggagaca tccgagttcc agaaaaagag aatcgacctg atggacgttt ccccgaagat
     3421 ggtattctcc gtggctacat ccatgattcc attcctgcag aacgacgacg cgaaccgcgc
     3481 cctgatggga tctaacatgc agcgtcaggc cgtgccgctt ctgactacag aggctccggc
     3541 agtaggtaca ggtattgagg gcaaggctgc cgtagactcc ggtgtctgcg tgctggctaa
     3601 gaatgccggt gtggtagagc gttccgcttc caacgagatc attgtaaagc gcgactcaga
     3661 cggacagaag gacgtatacc gcttaactaa gtttacacga agcaaccagt ccaactgcta
     3721 caaccagaag ccaatcgtct acaagggcga ccatgtagag gctggcgagg tgattgcaga
     3781 cggcgcttcc acctgcaacg gcgagatcgc ccttggaaag aacccgttaa tcggattcat
     3841 gacctgggag ggctacaact acgaggatgc cgttctgtta agcgagagac tggttcagga
     3901 ggacgtatat acttccgttc atatcgagga gtacgaggct gaggcccgcg acaccaagtt
     3961 aggaccggag gagatcacaa gagacgttcc tggtgttggc gaggatgcgt taaaggatct
     4021 ggacgagaga ggaatcatcc gtatcggagc tgaggtccgt gccggagaca ttctggtagg
     4081 aaaggttact ccgaagggag agacagagct gacggcggag gagagacttc tgcgcgctat
     4141 cttcggcgag aaggccagag aggtccgcga tacctccctc aaggttcctc acggcgctta
     4201 cggaatcatt gtggacgcca aggtgttcac gagagagaac ggagacgagt taagcccagg
     4261 cgtaaacgag acagtccgca tttacattgc ccagaagaga aagatctctg tcggcgataa
     4321 gatggccgga cgtcacggaa acaagggtgt cgtttcccgt gtgcttccag ttgaggatat
     4381 gccgttcctt ccgaatggac gtccgctgga tatcgtatta aacccgctgg gcgtgccttc
     4441 acgtatgaac atcggacagg tcctggagat ccacttaagc cttgcagcca aggcccttgg
     4501 atttaacgtg tccactccga tttttgacgg cgcgaacgag acggatatcg cagataccct
     4561 tgagctggca aacgattatg taaacagctc ctgggaagag tttgaagaga aatataaaga
     4621 caaggtcgat gagaaggtaa tggagtacct gggaacccac ttagagaaca gaaagctctg
     4681 gaagggcgtt ccgttaagcc gcgacggtaa ggtccgtctc cgcgacggac gtaccggcga
     4741 gtactttgac agcccggtaa ccatcggaca catgcattac ttaaagcttc atcacctggt
     4801 tgacgataag atccacgccc gttctaccgg accatactcc ctggttacac agcagcctct
     4861 gggaggaaag gcacagttcg gcggacagcg tttcggagag atggaggttt gggctctgga
     4921 ggcgtacggc gcatcctaca ccttacagga gatccttacc gttaagtctg acgatgtggt
     4981 tggccgtgtg aagacatacg aggccattat caagggcgaa aatattcctg agccaggcat
     5041 tccggagtcc ttcaaggtgc tcttaaaaga gcttcagtcc ttaggtctgg atgtgagagt
     5101 gcttcaggag gacggctctg aggtagagct gactgaaaat atcgattacg gcgatactga
     5161 tatccgctcc atccttgagg gagacagcag agagtactct cagaacgagt ccttcgagaa
     5221 gatgggatat cagaagcagg aattcaaaga ggacggagag ctgacttctg tggaatccga
     5281 aagcttttca gacgactaca cggatgacta tgaaaacgat caggatgact catattctga
     5341 cgacgaagaa taatagaagg gagtaccgct catgccagag acaaatgaaa cttatcagcc
     5401 attgacattt gatgcaatca agatcggttt ggcttctcct gagaaaatct tagagtggtc
     5461 ccacggcgag gttaaaaagc cggagacgat caactacaga accttaaagc ctgagaagga
     5521 cggtctgttc tgtgagagga tcttcggacc gagcaaggac tgggagtgcc attgcggtaa
     5581 atataaaaag atcagataca agggtgttat ctgcgacaga tgcggcgttg aggttacgaa
     5641 agccagcgtc cgcagggagc gtgtcggcca cattgcgctg gccgccccgg tctcccatat
     5701 ctggtacttc aagggtatcc caagccgtat gggcttaatc cttgacattt ccccgagaac
     5761 actggagaag gtgttatact tcgcctccta cattgtgctg gatccgggaa aaacaagcct
     5821 gcagttcaaa caggtgctct ctgagaagga gtaccgcgac gcagtggaga acttcggcta
     5881 cggcagcttc cgcgtgggaa tgggagccga ggcagttcag gagcttttaa ggggaatcga
     5941 cctggagaag gactccgagg acttaagaaa gcagttaaag gacgccacag gccagaagag
     6001 agccagaatc atcaagagac tggaggttgt agaggccttc agaaactctg gaaataagcc
     6061 ggagtggatg attatgactg tgattccggt tattcctccg gatatccgtc ctatggtgca
     6121 gttagacgga ggccgttttg ccacctctga cttaaacgac ttatacagaa gaattatcaa
     6181 cagaaacaac cgtctggcca gacttctgga gctgggcgcg cctgatatta tcgtgagaaa
     6241 cgagaagaga atgcttcagg aggccgtaga cgccctcatc gacaacggcc gccgcggacg
     6301 tcctgtgaca ggacctggaa acagagcgct caagtctctc tccgatatgt taaagggtaa
     6361 gcagggacgt ttccgtcaga accttctcgg aaagcgagtt gactactccg gacgttccgt
     6421 tatcgtcgtt ggaccggaac tgaagattta ccagtgcggt ctgccgaagg agatggcgat
     6481 cgagctgttc aagccgttcg ttatgaagga gctggttgcc aagcagtacg ctccgaatat
     6541 taagaatgcc aagaagatgg tagagcgtct ccagccggct gtgtgggatg tgttagagga
     6601 tgttattaaa gagcatccgg ttatgttaaa ccgcgcccct acactgcaca gactgggaat
     6661 tcaggccttc gagccgatcc tggtagaggg taaggcgatt aagcttcatc ctctcgtatg
     6721 tactgccttc aacgcggact tcgacggaga ccagatggcc gtccaccttc ctctttccgt
     6781 agaggctcag gcagagtgcc gtttcctttt actgtctcct aacaacctgt taaagccttc
     6841 cgacggaggt cctgtggccg ttccttccca ggatatggtc cttggtatct actacctgac
     6901 ccaggagaga cctggcgtga agggcgaggg catggcgttc aagagcgtga acgaggcaat
     6961 cctggcttac gagaacaagg aggtaacgct ccactccaag gttaaggtga gaatgacaag
     7021 acagatgccg gacggaacgg agaagaccgg tattgtagag tctaccgttg gacgcttcat
     7081 tttcaatgag attatcccgc aggatctggg atttgtggac agaagcattg agggcaacga
     7141 gctgaagctg gaggttgact tccatgtggg caagaagcag ttaaagcaga tccttgagaa
     7201 ggttatcaat acacacggag ctacccagac agcgattacc ctggacgata ttaaggccat
     7261 cggctacaag tactctacaa gagccgctat gaccgtatct gtctccgata tgacagtgcc
     7321 ggccagcaag ccgaagctga tcgcagacgc tcaggctacc gttgacacca ttgcaaagaa
     7381 cttccgccgc ggtcttatta ccgaggagga gagatataaa gaggttattg agacctggaa
     7441 ggcaactgac gaccagctga ctcatgacct gctgacagga cttgacgcat acaacaacat
     7501 cttcatgatg gctgactccg gagcccgtgg ttccgataag cagatcaagc agctggctgg
     7561 tatgcgaggc ctgatggcag atacgacagg acacaccatc gagcttccta tcaagtccaa
     7621 cttccgtgaa ggtcttgacg tactggagta cttcatctcc gctcacggcg cccgtaaggg
     7681 actttccgat acggctctgc gtacagccga ctccggatac ctgacaagac gtctggttga
     7741 cgtttcccag gatctgattg tccgcgagga tgactgctgc gcaagcagag gcgagattcc
     7801 gtatatggag atcaagggct ttacagacgg acaggagact atcgagagcc tgcaggagcg
     7861 tattacagga cgcttcattg ccgaggatat cgtggatcct gacacaggcg agattgttat
     7921 taaggcaaac cacatgtgta ctccgaagcg tgcggccgcc gttatgaagg tattagataa
     7981 gcttggcaga aatactgtca agatccgtac cgtattaaca tgtaagtccc acatcggtgt
     8041 gtgcgcgaag tgctacggcg ccaacatggc gaccggccag gccgtacagg tgggcgaggc
     8101 agtcggaatt atcgccgctc agtctatcgg tgagcctggt acacagctga ccatgcgtac
     8161 gttccataca ggcggcgtgg ccggcggaga tatcacacag ggtcttcctc gtgtcgagga
     8221 gcttttcgag gcccgtaagc cgaagggact tgcgattatc gcagagttcg gcggtgtggc
     8281 tacgattaag gatacaaaga agaagcgcga gatcattatc acagataatg agactggcaa
     8341 ttccaagacc tacctgattc cttacggttc ccgtatcaag attcaggacg gcgcggtatt
     8401 agaggctgga gacgagctga cagagggtag tgtaaatccg cacgacatct taaagatcaa
     8461 gggtgtccgc gcagtacagg attacatgat ccaggaggtt cagcgagttt accgcttaca
     8521 gggtgtagag atcaacgata agcatatcga gatgatcgtg cgccagatgt taaagaagat
     8581 taagatcgag gagagcggag attctgacgt gcttccggga acatccatgg acgttctgga
     8641 tttcaacgac atgaacgacg ctttaatcgc agagggcaag gaaccggcaa tcggccgtca
     8701 ggttatgctg ggtatcacca aggcttctct ggcaaccgat tccttcttat cagccgcttc
     8761 cttccaggag accacgaagg ttctgacaga ggccgctatt aacggcaagg tagataacct
     8821 gatcggtctg aaggagaacg taatcatcgg taagctgatt ccggcaggaa caggtatgaa
     8881 gagataccgc accatcaaac tcagcacaga cggcgaggag caggtgaacg agtccgttga
     8941 ggaagaggag attctggaca atgagtatcc ggagagcgga gagttagacg aggcagagca
     9001 gattgttctg aacgaggacg acttaagcga ggaataagat gaaatagtcc tgatttgaaa
     9061 gttgggatga aagaataaaa acaaaaacgg gaagcgttcc gccagcctct gtgggggtgt
     9121 ggaacgcttc ccgttttttg cgaaaactct tcgattatcc tggaatttct ctatttctct
     9181 gatggccttt agatgcgcaa ggaaaaattt tcggtgactt taagtggaac aagaaaattt
     9241 ttccttgcgc atccgttttt catttcatcc ctgctgattt tataagactt taatccaggt
     9301 ctgcgaacag cggagtggag agataccgct ctcccgtgtc ggggagaagg actacgatag
     9361 ttttaccctc attttccggg cgtttggcca gctctgcggc cgcccaggcg gctgcgccgg
     9421 aggaaatgcc caccagaatg ccttcttttt gtccaatcat ccttccagcg gcgtaggcgt
     9481 cctcattgga aacctgaatg atctcgtcat agatggaggt atcgagaaca gctgggacga
     9541 agcccgcgcc gataccctgg attccatggg ggcctggctg gccgccggaa aggacagggg
     9601 aggaagcagg ttctactgct acaattttaa catccggttt ttttgatttc agataggttc
     9661 ctactcctgt gacggttccg ccagttcccg ctcctgccac gaaaatgtct acttttccgt
     9721 ccgtatcgcg gtagatttca gggccggtgg tggctatgtg agccgctggg ttagctggat
     9781 tcgtaaactg gccggcaatg atgcttccgg ggatctgagc cgccagctcc tctgcctttt
     9841 tgatggctcc ggccatgccc ttagagccgt cggaaagtac cagctccgcg ccgtaggcct
     9901 tcatcagcag gcgccgttct atggacatgg tttctggcat gacgataatg acccgcaggc
     9961 ccctggcagc cgctacagag gccagaccga taccggtgtt cccggaggta ggctcaataa
    10021 tcacagtatc ttttgtaagc ttgccctgag ctgcggcatc atctaacata gacttggcta
    10081 ctctgtcttt tacagagccg gccggattga aaaattccag cttggccaac agcctggctt
    10141 tcagattcag ctctctttcc aggcctgtca gctccagaag aggcgtattt ccaattaact
    10201 gttctgcaga tgtataaatg tttgccataa ttgcgtctcc ttttcctgct ttttttagtt
    10261 ggcagaatta tagggctttt ttttgatatt gtcaatatgc aggaagcaga agttaagttt
    10321 gcatttcagg caagattttt gtaagaaaat agatcatgcg tttcacactg gattatgcta
    10381 gaatgaaaag caggatcata aaaaatacga aaagaataca taaaagaagc cgaaaacaga
    10441 atagcggcag gaggaataga aggatgagaa aacaaaattt tatttacggt gcagtctgcg
    10501 tgatggcagc tgcaggaacg ctctgtctgg cgccggggat tttaaacggc atgggaaagg
    10561 gggaaaaaca gatttcctct aagactgtcc agacggcaga tgcgctgacc tcggaaacca
    10621 gggaacaggt ggagacgaca atggccaata cctatgaaag ccttggaatg aagaaggttt
    10681 cagacactgt ggttgtgacg gcggatgcgc tccgctaccg aagcgctccg gatacctcgg
    10741 cagacaatgt gaaggggacg attccaggag gaaccaggct ggaacggatt tacgagggaa
    10801 acggctggag tgtggtaaag acagggggag gggaatacta tgtttcttct tcctatgtaa
    10861 aaaaggctga cggttcccag aatcaggcag atgcccagag ccagaacgcg tcggaaaata
    10921 agaaggaatc ccaggctcag acgaaagaga gtgctggcgg cccgggcgga tctgccggct
    10981 cagagggagg agagactcca gctgtacagg agattggcct ggacggaagc ctgccctatg
    11041 ccggattttc aaaaatcaac agcggaaagg ctgtgctgta taagagcacg gcgcagaaca
    11101 ggaaaaataa gaccattgca gtcaatgcag gtcacggcac aagcggaggc agcagtgtga
    11161 aaacccagtg ccatccagac ggaagcccca aggtaacagg gggaactacc gcctccggag
    11221 ctgttatggc tgtggctgtt tccggcggca tgacctttgc agacggtacg gcggaggcta
    11281 aggtgactct ccagatggcg aagattctga aggatcgtct gctggcggag ggttacgacg
    11341 tgctgatgct cagagacggg gacgacgtgc agctggataa tgtcgccagg tctgttctcg
    11401 ccaaccgcta tgcagactgc cacatttccc ttcactggga ttccacgtca aacgacaagg
    11461 gatgctttta tatgagcgtt ccaaacaatg cctcctaccg tgccatggag ccggtagctt
    11521 cccactggca ggatcacaac cgcctgggcg aagctttagt gggaggtctg cgggacgcag
    11581 gaaataagat tttttccggc ggatccatgg aaatggatct gactcagact tcctattcta
    11641 ccgtgcccag cgtggatatt gagctgggag acaagggatc cagccattcg gacgccgtct
    11701 taaaccagct ggccgacggc ctggttatgg gagtcaaccg ctttttcggc cagtagagag
    11761 agcacataca tatagaatat gcgccttcct tgtcctgtgc tgtcctattc tcccataaac
    11821 agggagactg agaggcagga agaaaaaatg cagttcatat ttcacacgcc tcgtacatac
    11881 cttagaaata gctaaaatga cgagcaggta tggaggggtg gagttgaacg acaggaatac
    11941 agaagttctg gaacagtatg atatggaaat tttctccgtc aggagagggc gcggatcctg
    12001 gatttgcgag acagacaagg gactcaggct ccttcgggag tataagggaa ccacaaagcg
    12061 gctggagttt gaggaggagg tgctgaacat cctccagaac agcgggattt ccaaggtgga
    12121 tcagtatgtg agaaataagg aaggggagct tcagtctgcc gctccggacg gcctcagata
    12181 cattgtgaag gaatggtttt ctgaggacga gtgcgacatc agggacgaga acgaggtggt
    12241 gaaagccgcc gggcagattg caaagctgca ccggattctg agaggcatcc agctgaaaga
    12301 ggagtggaat ctgggctcga ttctggcaga gccgatggag gcggaattcc ggcgccataa
    12361 cagagagctt cggaaagcca gggcctttat cagcagaaaa cgtggaaaat cagactttga
    12421 gctctgcgtg attggcaatt tcgcgccgtt tttggagcag gcgctggagg cccagagagg
    12481 tcttgagcag atggcggaag aaggaaaaga accgcctcat tatctctgcc acggcgagct
    12541 gaaccagcac catattttaa tggggggaaa ggaagcggcc attatagagt tcaaccggat
    12601 gcacctgggc gtccaggcgg cggatctgta ccattttatc agaaaggtga tggagaagca
    12661 cagctggaat cctactctgg gcatgcggct tctggaggcc tacgaccggg tgcttcctat
    12721 gggggcaaag gagagagaat atctctacta tctgttcctg tatcctgaaa aatactggaa
    12781 gcagctgaat ttctattaca atgccaataa ggcctggatt ccggccagaa atgtggagaa
    12841 gctccggagc ctggaggagc agcaggaggt gagaaaccgg ttcctgggga tgattcgagg
    12901 ctcatgacag aacaggaaat cacttctgct ttatttttcc gccggaatat actataattt
    12961 aggagaaata agtgttttaa gcaatacgac ggctgaacag ggccgcaata cagaaatggc
    13021 gcaggaggaa ttttagaatg aaagattaca aagcgatcta tgaggaatgg ctgtccaatc
    13081 cttactttga ccaggagacg aaggaggagc tcagagccat ccgcgcagac gagaaggaga
    13141 tcaaagagcg tttttacatg gatctggagt ttggaacagc aggccttcga ggcgtcatcg
    13201 gcgctggaat taaccgtatg aatatctata ccgtaaggcg cgcgactcag ggactggccg
    13261 attatatttt agagcaggga ggggctgaga gaggcgttgc cattgcctac gattcccgcc
    13321 gtatgtcccc ggagttttcc gatgaggcgg cccgcactct ggcggccaac ggaatcaagg
    13381 cgtaccgctt tgaatctctg cgtcctacgc cggagctgtc ctttgcagtg cgggagctgg
    13441 gctgtatcgc cggaattaat attacggcca gccacaatcc gccggagtac aacggctaca
    13501 aggtatactg ggaggacggc gcccagttta ctccgcccca cgataaggga gtgacggaga
    13561 aggttatggc aatcacagat ctctccgctg tcaggactat gagccgggag gaggctgagt
    13621 ccagcggcct gtatgtgacc atcggagctg agattgacga caagtacatt gcccaggtga
    13681 aggcccaggt agtgaaccag gcggcgattg acagaatgca ggatcagatt tccattgtct
    13741 acactcccct tcacggcaca ggaaatattc cggcccgccg cgttatgaag gagctgggct
    13801 ttgagcatgt gtacgttgtg ccagagcagg agctgccgga cggcaatttc ccgactgtaa
    13861 gctatccgaa tccggaggca gaggaggcct ttgagctggg gcttaagctg gcgaaggaga
    13921 agaatgcgga tctggtactg gcaacagatc cggacgcaga ccgtctgggc gtctatgtaa
    13981 aggacgataa atccagcaag tatattccgc tgacaggaaa catgtcggga gctctgctct
    14041 gcgattatgt gctgagccag aagcaggcaa acggccagat cccagcggac ggccaggtgg
    14101 taaagtcgat cgttacgaca aatctggtag acgcagtggc cgcccactac ggcgcagagc
    14161 tgatcgaagt gctgactggc tttaagtgga ttggaaagca gattttaaag aacgagcagg
    14221 aaggaaaggg aacctacctg tttggcatgg aggaaagcta cggctgcctg attggaagct
    14281 atgccagaga taaggacgcc atttccgcca cagcggctct ctgcgaggcg gctgcctact
    14341 ataaggagaa gggcatgact ctgtgggatg ccatgattgc catgtacgag aaatacggct
    14401 actataagga cgccgttcag gccatcagct taaagggtat cgagggactg gagaagattc
    14461 agaagattat ggagtatttc agaaacaaca ctccggctga atttgcagga agcaaggtta
    14521 tctctgtgag agattacaag gcagatacca tccgcgacat ggcttccgga gaggtaaagc
    14581 ctaccggcct tccgtcctcc aacgtgctct actatgacct ggaggatcag gcatggctgt
    14641 gcgtgcgccc gtccggaaca gagcccaaga tcaagttcta ttacggcgta aagggaacct
    14701 ccctggcaga tgcagacgag aagtccgaga aactgggaca ggctgttcag aagctggttg
    14761 agccgatgct gtaaagagga aaatagaacg aggaaaactt ttcggtgact ttaaacggaa
    14821 caagaaaagt tttcctcgtg cattttttct gtattttttc tatgcaaatt tccttgacaa
    14881 ccataaaaaa atatgatatt ttacttaagt attgactgcc taagacagca ggtgccgcaa
    14941 ggcataaggt aaaaacgcct gccgaggaaa cgtacactta ctgatgtaaa ttgtgcctcc
    15001 ctgtcttgtg cagggaggtt ttttctgtaa gactcctggc ggttcatacg acgaaaataa
    15061 aacaggaggt aaaccattca tggcaaaagt tgagttaaag cagcctatcg ttgctgagat
    15121 ttctgagtta ctcaatggcg caaagtctgc agtagttgtt gattaccgcg gattaactgt
    15181 tgagcaggat acacagcttc gtaagcagtt aagagaagct ggtgttactt acaaggtata
    15241 taagaacacc atgatccgct ttgctgcaaa gggaactgag ttcgaagctt tagagccgaa
    15301 tctggaagga cctacagcat tagctgtatc caaggaagac gctactgctc cggcaagagt
    15361 attagctgag tttgctaaga aggcagacaa gttagagtta aaggccggtg ttgtagaggg
    15421 cacatactac gatgcgaagg gaatccaggt tatcgctact atcccgtcca gagaagttct
    15481 tctcggaaag ttactgggaa gcatccagtc cccgatcgca aactttgcac gcgttatcaa
    15541 tcagatcgca gaggcaaagg aggcttaatt tctcatatga tatgggctgc atagccgcat
    15601 agagaaagag ccgtctgatt ttttgaagga atcaggagag gccgggaaag ccggcagaac
    15661 tatattttaa aacattaata aacaggagga aattaaaatg gcaaagttaa caacagctga
    15721 gttcattgag gctattaaag agttatccgt attagagtta aacgagcttg taaaggcttg
    15781 cgaggaagag tttggtgtat ccgcagcagc aggcgttgta gttgcagcag caggcggcgc
    15841 aggcgaggca gctgaggaga agacagagtt cgacgtagag ctgacagagg ttggcgctaa
    15901 caaggttaag gttatcaagg ttgttcgtga ggctacaggt cttggcttaa aggaagctaa
    15961 ggaagtagtt gacggagctc cgaaggtagt taaggctggc gtttccaagg aagaggctga
    16021 ggaccttaag acaaagttag aggcagaggg agcaaagatt acattaaagt aattcattgc
    16081 cattctatac aaactaaatg cattacagcg aaaaagaagt ccgggacgca ttgtgcgttt
    16141 cggacttctt tttcgtttct gaatctcaaa cgggaatatt ctaaattgag atgaaaattt
    16201 tggaattctt ttgtataata gtatgtaatt gagtacaagg gaggggatag gatgaacgta
    16261 tcagagacaa ttaagacgag aacttcgctt cgcgtttatg acgacagaat gatagcagat
    16321 tccgacctgg atcagatttt ggaggcggct tttctggcgc ctacagccgg aaatcagcag
    16381 ctttattcga ttattgtaat taagagtcag gagacgaagg acaagctttc taaaagctgc
    16441 gacaatcagc cgtttatcgc caaggctccg gtgcttctgc tctttctggc ggatcagcag
    16501 aaatggtttg attactacag gtcaaagggc tgcatggagt ttgccgccag ggaggagggg
    16561 ctttcctggg aggaacccaa cgaatcggat ctgctgcttt ccattgagga taccatgatt
    16621 gccgcccaga acgctgtgct gatggcggaa tctctgggaa tcggatcctg ctacattgga
    16681 gatattctgg aaaattatga gtaccacaaa gagctgtttc agctcccgga tcacgcagtt
    16741 cccatttccc ttctgtgcct gggatattat aaggaaggcc acaagcgtgt atacagaaaa
    16801 agatttgaca agaaatacgt agctttcgag gaaacctata aaaggctgtc agacgaggag
    16861 ctggaccaca tgtttgctga aaaggcctcc ggcttcgtga aagggccggc gatcaccgcc
    16921 gacaattttg cccaggcctt ctataagaga aagacaggag cagcattctc caaggagatg
    16981 gccagatctg tgagagccat gctcaaagcc tatgagggca aacaggaaga ggagagataa
    17041 aggcggcgtc tgcagacaga acaaatgaga aatgcagagg catacggcgc agcaggcagg
    17101 agcatacggc gcggctagac ggcgcagtaa gatagcgcgg caaatggaag atacgggaga
    17161 agaacatgga aaaacagaaa ttagaggaac agctcagaca gtttaaagag gcggtttcca
    17221 gtgcgtcctg ccttttaatt ggcgtgggag acgagtgggc ggctggagaa aagcgttcca
    17281 gagaagaact tgcagaggct tatcaggccc tctattctct gacagaggga aaggactatt
    17341 ttattatcac gactgtgacc gacgggctga tacgggaaag cgcgccggat caggggagga
    17401 ttacagcccc ctgcggcaat gagcagtggc agcagtgcag cagggcctgt accagggata
    17461 tctgggagcc gggagagatc ccagacggcc tctgccccca ctgcggcgcg ccgctgacgg
    17521 gaaataccat ttttgcagag gcctacattg aggagggata tctgcctcag tggaaggctt
    17581 accaggaatg gctgggaagg actctgaaca gggagcttct ggcggtggag ctgggggaag
    17641 gttttctgct tcctaaattg attcggtggc cctttgaaaa gacggtcttt tttaacaaga
    17701 aggcgcatat gtatcgtgtg aatgagacgt ttgcccaggt gtcagaggat atcggggaca
    17761 gatccgtctc tgttcaggcc aattccgtgg attttgtgag gatggccgcc gcatgtttaa
    17821 aaaactgacg ggtaatcatt gtctattctc cggctctgtg ttactatttt aagagcagcg
    17881 tcggtgcaga gatttatttc ccccgcatga cggcgcagac gaaagctaca gaagcgaaag
    17941 tcacgaaaga gaggtagaag cctgatggga gcaatcagca acgactggct tgagccgctg
    18001 agcgcggaat ttaagaagcc ttactataaa aaactgtacg agacggtgaa gcacgagtat
    18061 gagacgaggg ctgtctatcc agacgccaac gatattttca atgcgtttga atttacccca
    18121 ctttctcagg tgaaggtggt gattttaggg caggatccgt accacggcta cggccaggcc
    18181 catggcctct gcttttctgt caagccgggc gtggatacgc ccccttccct ggtaaatatt
    18241 taccaggagc ttcacgacga tctgggctgc tatgtgccga acaacggata tctgaaaaaa
    18301 tgggcggatc agggcgtgat gcttctgaat acagttctga ctgtccgcgc ccaccaggcc
    18361 aattcgcatc gcggaatcgg ctgggaggag tttacagacg cggcgatccg cgccttgaat
    18421 gagcaggacc gccctatggt gtttatttta tggggcagac cggcgcagac gaagaaagcc
    18481 atgctcacca atccgaagca tttgattctg gaggctcccc accccagccc gctgtcagcc
    18541 tacaggggat ttttcggcag caggcccttc agccgcacca acgaatatct gaaggagcat
    18601 ggaattgagc caattgactg gcagattgaa aatatttaac gagagggaac agtatgaact
    18661 tttttgaaat tttgaaggtt cttgtgctgg gaattgtgga gggctttacg gagtggcttc
    18721 ctatcagcag tacgggacat atgattctgg tggatgagat cattcacctg aatgtaagcg
    18781 aggccttccg ggaggtcttc atggtggtga ttcagctggg agcgattctg gcggtggtag
    18841 ttctgtactt ccacaagctg aacccctttt ctccgagaaa gactcagaat cagaaacggg
    18901 ctacgatccg cctgtggatg aaaatcgtgg tggcctgtat tccggcggca gtcatcggac
    18961 ttccctttga caatctgtta gataagctga tgaacggcta tgtggtttcc gccatgctga
    19021 ttctgtacgg cgtgtttttc attttactgg agaacagaaa ccgcggcgtg aagttcagga
    19081 ttcagcgggt gacgcagatt tccttccaga cggcggcggt tatcggactg ttccaggtgc
    19141 ttgccatggt tccgggaacc tcccgctcag gggcgaccat cctgggagct atgctgcttg
    19201 gctgctccag gggagcggct gcggagtttt ccttcttcct gggaattccc gttatgtttg
    19261 gggccagtct cttaaagatt gtgaaattta tgctggaggg agcttctttc cagatgtatg
    19321 agatttttta tctgattttt ggaatggctg tggccttcgg agtgtcggtc tactcgatta
    19381 aattcctgat ggagtatgta aagcagcacg atttcaagtt tttcggctac tacaggattg
    19441 tgctgggaat cattgtgctg tcctacttcg gaatttccgc tctggtgggg gcataaaggc
    19501 ctaaaacgcg tggcagggga ccgaaacagg agaaaacggc gcctgcgaag cgctggatga
    19561 gcgcaggcta aaacagatat cagaagatat caggcataaa aaatatatgg atgggagagg
    19621 tgttccggct gtttcggagg gcctctccca tttgttgtcc agggaaatca tacgtctatc
    19681 ttcccagcca gtcccgtata tatgagacaa gggggtggaa gatgtgaaac gatttcgcag
    19741 gcagacaggg attctgtttt tgatcgttat ggtggatctt ttgctggctc tgaacctggc
    19801 caggctggca ggaggagaga ggaaagtctg tgtgtccgaa ggagaatcag cccttcctgt
    19861 ctctgaggca ggagacggga ctttggagag ggggactggg aacgggggaa gaacaggagg
    19921 gggaggagag gagccgggcg aagagaatcg gtttctggct ctcacctttg acgacggccc
    19981 ccacccggtc tgcacgaagg agctgctgga cggcctgaga gagcggaatg tgaaggcctc
    20041 ttttttcctt ctgggggaaa atattcctgg caatgagcag ctgatccgtc agatgaagga
    20101 ggatggccat ctgataggaa cccattgcta ccgccatgta gatttgacca aggaggacgc
    20161 agagaccgcc atttccatga tccgaaagac aaatcgggag atcgaggcgg tgacgggaga
    20221 agaaccagtt tacataagac ctccttacgg aaaatggaac ggacagctgg aggacgccct
    20281 cgacatgacg cctgtgctgt gggacatcga caccctggac tggaagagcc agaacagcgg
    20341 gaaagtgctg aggtccattg aaaggaacgc cggaaagcat cagattgtgc tgatgcacga
    20401 catctttcca actacggtgg acgcggcgct ggcggccatt gacacattgg gggagcaggg
    20461 ctatactttt gttacagtag acgagctttt gattgactga caaaggaaat aagggaaggt
    20521 gcagacaaga tggatttatt tgactatatg agaagcaata ccatggagaa ggaggcgccg
    20581 ctggcttccc ggctgcggcc ctccaccctg gacgaggtag tggggcagaa gcatatcatc
    20641 gggaaggata agctgcttta ccgcgccatc aaggcagata agctgggatc tattattttt
    20701 tacgggccgc cgggaacggg aaagacgact ctggccaagg tgattgccaa cacgaccagc
    20761 gcccggttta cccagattaa cgctactgtg gccggaaaaa aggacatgga ggaggtagtg
    20821 aaggaggcca aggacgccct cggcatgtat gggcagaaga cgatcctgtt tgtggacgag
    20881 attcaccgct tcaataagag ccagcaggac tatctgcttc cttttgtgga ggatggaacg
    20941 ctgcttttga ttggagcgac cacagaaaat ccctattttg aagtgaacgg agctcttatt
    21001 tcccgatcca ggatttttga actgaagcag ctggaaaagg atgatattaa ggagcttctg
    21061 cgccgcgcgg tgacagattc tgagaaggga atgggcatgt accaggctgt gctggaaccg
    21121 gaggcagagg aatttctggc cgatatggcc aacggagacg ccagggcggc tctcaatgcg
    21181 gtggagctgg gaattcttac tacagagcgg gcagaggacg ggctgattca cattgacctg
    21241 gacgtggccc aggagtgtat ccagaaacgt gcggtgcgct acgataaggg gggagacaac
    21301 cactacgata ccatttccgc ctttattaag agcatgagag gatcggatcc ggatgcggct
    21361 gtgtactatc tggcgcggat gctctatgcg ggggaggaca ttaagtttat cgccagaagg
    21421 atcatgatct gcgcctccga ggatgtggga aatgcagatc ccatggccct taccgtggcg
    21481 gtcagcgctt ctctggccgt ggagcgggtg ggaatgccgg aggcccagat tattctctca
    21541 aatgccgcct cctacgtggc ctgcgcgcct aagagcaatt ccgctgtcaa cgccatcaac
    21601 gcggccatga aggcagtgaa aacccagacg ctgatgccgg ttccgcccca tctgcaggac
    21661 cgccattaca gcggcgcggc ggctcttgga cgggggctgg actacaagta cgcccacgat
    21721 taccccaatc attatgtaaa gcagcagtat ctgccggacg gcatggaggg cgcggtcttc
    21781 tacgagccgt cggacaatgg atatgagaag gagatcaagg cgcggctggc gtttctgcgg
    21841 ggaagtgagg agtaggaaag agcgtgggag gaaacgcagc cagccgatga accggcagat
    21901 tctgcgcatg gtctttcata gtttgcagcg gatttaattt acctttgcag ctattagata
    21961 gaaacagagg aaaagcctgg ctccagcttc atcggagcgg aaaggttttc cctctgtttt
    22021 ttatgttttt taattaaaaa atgaaccgac taccagtttg gctgctctta tagacaggta
    22081 taccaaaaag ggaaggagat atcagacagt tgaaagagac ggagcttgtg aaacggctga
    22141 tggccggaga tagggaagcg tttgatgccc tgtatgaatg ttataaggat caggctttca
    22201 ggaccgcctg gtttctggca ggaaacagag ccgatgcgga ggatattgtc caggacacct
    22261 ttgtgaaggt gtatgtgaat atagggcagc tgaagaatgc ggaaggtttt aaaagctggt
    22321 tttacaggat cctgacaaga actgcgtgga aacagtctga cagccggaag cgggaatttc
    22381 ctgacgagga aattttaatc cacgcagaca ttgcttcaga ggcgtcagag gatggcaatc
    22441 cagaacagat ttttaagaaa gaagagagac aacggctcag agcgattgtg gacggcctgg
    22501 atgaaaaata caggacaacg ctgattctct attattacag cgagtgttcc acaaagacca
    22561 tcgcgtcgat tatgggatgc ctggaaggaa cggtcaagtc ccggctgttt tcagccagac
    22621 gaaaggtgaa aatggaactg atgcgggaaa tgaaaaagga gggagctgtc tatgagcagg
    22681 aaggaagacg aagcaatcag ggaattgttt aaaggagagg cagagcgcat ggcggctccc
    22741 gactcgttaa aaacgcggat cgaccgggaa attgacagaa ttgagaatga aagaatcgag
    22801 aagagaaaag gttcagagaa ggaggcagtg attatgaagt ttcagaaaag aaaagtggcc
    22861 ctggcggcag cagtgattgt ggcgattgga agcattacct gttatgcgac aggaaagatg
    22921 acaggcctga tggtgggaag cagccacctg acggaggtat ccgaatacag cggccttgac
    22981 acagcggagg agaaggctgg atttgagacg ggaatgccgg aaaccttctc aaacggctat
    23041 gcttttaaaa acgtcaatac aggagacggc caggcggttg acgcggaggg caacggcata
    23101 ccgggaaccc agtatacgga catttttatg acctatgaga aggacggaag cgagattacg
    23161 gccagcatta tgccggaact gaaagaagag tctgcagaag aggcaggaga cgcagaggcg
    23221 aaaacgccgg aagcggctga gatcagagag atcggaggca ttacagtcag ctactatgag
    23281 acgaccatga aggtagttcc gccggattat gagctgacag agcaggacaa gaaggacatg
    23341 gaaaactcca atttcacgat ttcctatgga agcgatcagg tgtatgtgca gaaggtgaga
    23401 tccgtggact ggaaggcaga cggaaaggct tacaatttcc tcgatatgga aggaactgtg
    23461 gatgcagaaa ccctgttttc tatggcccag gacgtgatcc agggaaaata gagaagaaaa
    23521 aatataatag gtatagaagc agacagaaaa aaggaataga cagagccaaa aaatgcccgc
    23581 cgcaggttaa acacgcggcg ggcaaaacta tttagttcca ttctttttcg aagagaaaat
    23641 cgcggccatt gcggtgtttg ataccattgc ggagcgtatg gaattcattc cgcgcgcaac
    23701 tttccatagc atattctttg cccacggacg ccatgttgat ttttagggat ttttttgaca
    23761 taattatgga tagtaataaa attcatggca gctcttatcc agaaggagag gcaaaaaatc
    23821 ctcctgaaaa aggctgcaca tcataacttt taggtaagat gaaatgaaga aaatcaattt
    23881 ttatgtgtca gagatcgctt ttctctgttt tctggcagga tgctcgtctg ccccgccgga
    23941 tgcagagaag cagaatacgg tcaattatct gaattccatc cggacgcaga ccgtaaatgc
    24001 agagtccggc tctttcatta tcaatactga atggaacata ggaggagaaa ttgaaacggt
    24061 cggacgccag attgattttt ctcatcgggg ctctgaactg cattataaag aagctattta
    24121 tgattcgttt gcagatcctt ctgtgaagcc ataccagaca gcagaaacat cagaagacgg
    24181 gacttcctta attgtttcat caggaggtga caattttacc gttgaggttc ctctggataa
    24241 agctccctct ttggagcagt tttttgaagg tgtctgggat acgatacatt catcagaaat
    24301 cgaatgtatc gagacagcca agcagggaaa tagaacatcc tatactatcg tatattcttc
    24361 tgattactgc aaaagtaaag gaaatgatac ggaaattggt tcttctgtgc tccagtcaaa
    24421 aattctggaa ttggaactga tgccagatga aagcataaaa gcagttaaac tgaatacagc
    24481 cggatacgtt tcagggctgg atgcttcaga aacgccagtc agtcaaaaaa cggaactgta
    24541 tttcaattag aatattttaa cgcagctagc cgcaaagcct gctggtttcg cctgctctac
    24601 aatgatttaa gaaaaggctt tttgtttatg cgtttgtcgt ggcccgcccc ttaaaaaagc
    24661 tgtaaaaacc aaagaactat ggtataatgt accacagcag cattttggag tgaaagcgag
    24721 caaacagtct gggaagcaga cagaaaacgc ggagcgtgag tttgcgagta caggcagcgc
    24781 cagaatgaga gagatttgcg gatatgacgc agaaaataag gatatagtag gaagataaaa
    24841 cagaaaggaa tattccattg aataaacaga atgaaccaga gacaaacgcc atcaccgtca
    24901 gggatgtgac caagatttac cgtctgtatg acaagcccat tgacaggtta aaggaatctt
    24961 tgagcgtgac tcataaaaat tatcacaagg atttttatgc ccttcagaac ctttccttta
    25021 atgtgaagaa gggagagacg gtgggaatca tcggaaccaa cggatccgga aaatccacga
    25081 ttttaaagat tattacggga gttctcaccc ccacgtccgg ggaagtacag gtggacggaa
    25141 agatttccgc ccttctggag ctgggagccg gttttaacca ggactacaca ggaattgaaa
    25201 atatttacat gaacggaacc atgatgggct tttccaagaa agagatggat gagaagctcc
    25261 cggacattct ggaatttgcc gatatcgggg actttgtgta tcagccggta aagacctact
    25321 ccagcggtat gttcgtccgt ctggccttcg cgctctccat caacgtggag ccggagattc
    25381 tgattgtaga cgaggcgctg tctgtggggg acgtattttt ccagtccaag tgctaccgga
    25441 gaatggacga gctgaggaaa aatggcacga ccattgtcat ggttacccac gatatgggaa
    25501 gtgtgatcaa gtactgtgat aaagtagtgc tgttaaaccg aggagaattt gtggctgagg
    25561 gaccagccgg aaaaatggtg gatctttaca agaagattct ggcgggacag ctggattccc
    25621 tgaacgagga gctggcccag atgaacgact tttccgggga gggaatttct ggttcaggaa
    25681 aggacggaca ggagattttg tccgctgcgg aaagacagaa tgaatctgga cagaaaccag
    25741 gcctgatgaa ggataagatt acgatcaacg gaaacaggac agagtacgga gatggaaggg
    25801 ccgagatcat tgacttgggg ctgtgcgatg agcgggggaa tctgaccaac cttcttttga
    25861 agggggagat gttcacaatt aaagaaaaaa tccgtttcaa tacagagatc caggccccga
    25921 ttttcaccta cacgatcaag gacaaaaagg gcacggatct gtcgggaacc aacaccatgt
    25981 ttgagggaac ggatgtgaag cctgtgaaga agggggacgt ctacgaggta tccttcaccc
    26041 agaaaatgac tctgcagggc ggagagtacc ttctgtccat gagctgcacc ggctttgaga
    26101 acggggagca cgtggtgtac caccgcctct atgacgtggc gaacattacc gtcatttcca
    26161 acaagaatac agtaggcgtc tacgacatgg agtctcaggt ggagacgaag cttaccaggg
    26221 cggaagagta aaggaggcgg agcatgaagg acttaaataa gaaactgatt tcccttataa
    26281 gggaatacgg ggacgacagg acggcggccc tgaacagctg cgtggatctg gactgcttta
    26341 tggccctctc tcctctcagg gaaaaccttc tggagtggta tgagtttcag gcagacggag
    26401 agcttttgca ggtgggagcc gattacggcg ctctgacagg gctttttaaa agacgtgtaa
    26461 aagcggtaac ggtgtgggac gagtctgagg aacagctgga catagtcagg gagagatttc
    26521 cggatacctc tgagggagcg cctgtttcct gcgtgggagg tccgctgcgg gagctgcttc
    26581 aggcgggaaa gagatacgat tatgtggtct gtgcaggggg ctttcaagag cctgaggacc
    26641 agtgggcgga aatcctgcgg gatctggcaa agcctggcgg aacggtgaca gccgccgtct
    26701 gcaaccggtt cggactgaaa tatctggccg gagggaagag ggatcaggta agtcttacaa
    26761 gaaaccgcct gtccgcgctg tttcccggat gcgcctttta ctatcccatg ccggattacc
    26821 gggttccgac tgtgatttac tcagaccgct gccttccgtc aaagggggag ctggctggaa
    26881 tccatacgct gtatgatttc ccggagtatc cgtccgtcga cgtgggagcc gagtttgagg
    26941 ccgcctgtga gaacggacag tttgctaatt ttgcggattc ctttcttatt atctggaaaa
    27001 aaggagagta ggccatggca gagaccattt atgtaaaata taacggaacc aggcggaagg
    27061 actttcagat taagacggct atccggctgg agcagggaga aaagacagtg gataaaacgg
    27121 ctctctgccc ggagggagag gcccatatcc gttcctttga agaaaaatac cgtctgcttt
    27181 ctgaggagag cggacggctg acttttttaa agcctgaaat cagagacggc gggcgtacgg
    27241 cccggttccc cttcctgaca ggggacacgc tgtctaagcg gctgggggaa gcagtttccc
    27301 cggcagccgg agaagcgcag gaagacaggc gggagcgtgt gaagcaggcg gtaaaagagg
    27361 cccttgacac ggctgtttcc tgccgtttgg agtatgtgtc tgaattcaac gtgacgccgg
    27421 agtttctgga ggtgttcgga cagccggcgg ccggagagaa ggcggagatt tcttcctttg
    27481 aagagcagaa aaaggccttt gaggaggcgt ttggagaaca ggagacgtcg tttcggaccg
    27541 ccaatgcaga cgctctgttt gacaatgtta tgatgtgccg gaatccagaa tatgaggagg
    27601 gcggggaggc cctggaggag attcccatag ctctggacta cgagtgggta tttccgtttc
    27661 ctgtgccggt gagcttcctg aagtacaggg ttctcttcta tttttatgag gatcaccgtc
    27721 cgatgcttgc agatctgttt ccggaacgca gtgagttcct gacagaattt tccctggatg
    27781 cgaagctgtt tcctgtctgt gaggcgatgg agcggtcctt ccagagctat gtccatgggg
    27841 agaatcagag gatccttcag gacaattact acgtttccac taagaccatg aaggagctgc
    27901 gccaggcaga acaggagatg gagcgggtaa aagaccggct cagccagctg aaggcggaga
    27961 acgcggagaa ggacattgcc ctcagaaagg cccaggaggt tcagcgcctg acgaacaacc
    28021 atgtggcgaa tctggagacc atgatcgggg atctgcgccg ggaaatcggg gagatgggaa
    28081 aaacactttc ttacttaaac cgccacgagg ccctgatttt caaggccaga agaaaggcag
    28141 gacaggcctt taacagagcg gttccgaaag gtacggtaaa gagaaaaaag ctgggctatg
    28201 tgaaaaatac ggtgcttcac ccggcctcca gcctgaaact gtacaccaca gacgagggga
    28261 agaaccgcat taagggacac tttgagattg gggacgagta cctgacttac ggaaagctgg
    28321 tatttccgaa agaggagcat ccgatggttt ccatcgtgat cccggtgtac aaccagattc
    28381 actacaccta cctctgtctg gcctcgattt tagagcatac gaaggacgtg agctacgagg
    28441 tgattatcgc ggacgacgtg tccacagacg ccacagagca tttatcggag tttgccgaga
    28501 acctggtcat ccgccgtaac aagacaaacc agggattttt aaggaactgc aaccaggcgg
    28561 ccgaggcagc caggggaaaa tatgtgatgt tcttaaacaa cgacacccag gtgacggagg
    28621 ggtggttaag ctctctggtc cgcctcatcg agtctgacgg caccatcgga atggtgggat
    28681 ccaagctggt atatcccgac ggacggctcc aggaggcagg cggaattatc tggagcgacg
    28741 gttccggctg gaattacggc cgcctggacg atccggacaa ggcggaatac aactacgtca
    28801 aagatgtgga ctatatttcc ggagcggcta ttctgctgtc tgtgaagctg tggaagcaga
    28861 tcggcggctt cgacgagcgg tttgccccgg cctactgcga ggactctgac ctggctttcg
    28921 aggtgagaaa ggcgggatac agagtggttt accagcccct ctccaaggtc atccacttcg
    28981 agggcgtttc caacggcacg gacgtcaacg gaagcggctt aaagcggtac caggtggaga
    29041 acagcgaaaa actgaaggaa aagtgggcgg aagagtttaa gaagcagtgc gtcaacacgg
    29101 gaaatcccaa tcccttccgt gccagagagc gcagccaggg caagaaaatc atcctggtgg
    29161 tggatcacta cgtgcctacc tttgaccgtg acgcaggatc gaagaccacg ttccagtacc
    29221 tgaagatgtt cctgaaaaag ggatatgtgg tcaagttttt aggggacaat taccttcatg
    29281 aggagcctta ttccacgact ctgcagcaga tgggaatcga gatcctctac ggccaggagt
    29341 atgtgacggg catctgggac tggctggata aaaatgggaa cgagattacg gcagcctatc
    29401 tgaacaggcc ccacattgcc acaaagtacg tagattacat tgcagagcat accaatatga
    29461 agatcatctt ctacggccac gatctgcatt tcctgcggga gttcagggaa tatgagctga
    29521 ctggagatcc ggcgaaaaag cgggattccg actactggaa atccattgaa tttaccctga
    29581 tgcacaaggc ggcggtgtct tactatccgt cggaggtgga gattgaggcg atccatgaga
    29641 ttgacgacac ggtgaaggcc aaggcgatca cagcctatgt gtacgaggac ttcttaaaca
    29701 atctgaatct ggactttgag aagagggagg gcctgctgtt tgtgggaggt ttcgcccatc
    29761 cgccgaacgc ggacgccgtt ttatggtttg caagagaggt attcccgctg atccgggaaa
    29821 aactgtctgt gaatttctac attgtaggtt ctaaggtgac agaggagatt aaggccctgg
    29881 aacagcctgg aaacggcatt gtcgtgaagg gctttgtcag cgaggaggag ctttctgagc
    29941 tttaccggac ctgccgtctg gtggtggttc ctctccggta cggcgcaggc gtcaagggca
    30001 aggtggtgga ggctatctac aacggagcgc ctatcgtcac cacctctgtg ggcagcgagg
    30061 gaatccctgg cgtagaggac gtgctcttgg tggaggatca gccggaggcc ttcgccgata
    30121 cggtggttaa aacgtacagc gacacagaaa agctcagaga gctggcagaa aagactcaga
    30181 gctatatcag agatcacttc agcatcgacg cggcctggga ggtaatccgg gaggattttg
    30241 agtgatgaca gaccagagaa ataaccatct gataggcaat ggcctcagca gagaggcggt
    30301 gaagttcatc gccattttga ctatgacggg aaaccacgcg gctgcagctt tgctgccgcc
    30361 cggccttccg cgcagtcttt tagtaaatat cggatatttt accgccgctg tcatgtgttt
    30421 tttcctggcg gaggggtttc ggtataccag ctctaaaagg cgctatggag agaggctgct
    30481 gtttggcgca gtcctctccc agctgccatt ttttctggtg ttccggctta tgacgtttaa
    30541 tatgatgttt acgctccttc tctgctttct gctgctggtg gtaagaaccg acgacaggtt
    30601 tgcgggaaaa cggctggttc tggggatttt aattgtattt gccagcggcc tctgcgactg
    30661 gccggtgatg gcgcctctct tcactctgct gttctggaac gcaggggagg actgggaggc
    30721 cagaaagaag gcctgctggt atgtggtcat cctgtacgca gtttttacgt ttgtcagcgt
    30781 ctgcggactt cttttaagcc ctgtggaggc cctgattcat acagtcctct cctctgccgg
    30841 ccctgcggcg gcctgcctta ccatcctgtt tctctataat gggaaggaga cgaaccgggg
    30901 cgggagagcg ggaaaagcgc agaaatggtt tttctatctc tattatccag cccacctgct
    30961 ggtcatcggc ctgataaaaa tggccatggt actgtaataa tgataagaaa aagaagcttt
    31021 ctgaatccag cgaatctggc ggagagcttc tttttttgat aaaaaaattt acgctctttt
    31081 tcccaaacat cccttttgat tttacttaga aatgatacga taacagtacg cttctgaagg
    31141 gaaaaacctc catggaggaa taggaaaggg aaatttggat gattaaaaca tatgtattag
    31201 acacgaatgt attaattcag gctccggatg ccatagaacg ttttgaagaa caccgggtag
    31261 tccttcccct ggctgtgttg gaggagctgg atcatctgaa aaatgcagat ggggaaaaag
    31321 gagccaatgc aagggcggca attcgtttat tagaacggct gagacagaat ggggacctga
    31381 cagaaggcgt agaactccca tcagggggca gattaaacat agaaaagaac tttattaacg
    31441 aagtacttcc ggaagatctt ccggaggagc ggatggataa caggattcta aaagtctgtc
    31501 aggggctttc aaggacagag aaggggcagg tcatcctggt gacaaaggat ctgctcctca
    31561 gaatcaaagc tcagattctg ggagtcaggg ccgaggattt tatctctgag caggtccggg
    31621 ctgatcagga acagtaccgg ggcagagcgg aagcttatgt gccggaggac agctttaagg
    31681 agtttaaaaa gaaaggaatc cctgtttctg aagcctatca gaccgatgag aagggaaacc
    31741 gtataaagct ggagctgttt gaaaatgaat ttctgatttt gcgaaatgaa ctgaatccgg
    31801 ataaaacaca gctgggccgt gttgaaaacg ggaaaattaa aaaattagaa tacagaaagc
    31861 agaagcccta tggcattact ccccgcagcg cagggcagtg ttttctccag gaggctttaa
    31921 tgcagccggc tgcttccgct cctcttgtca ttgtgaaagg aatggcagga accagcaaaa
    31981 ccttttatgc gctggctgtg ggactggaaa agctgctaaa tcatccaaac ggcgaataca
    32041 ggcggatgct gatctgccgt cccaatgccc agtttgacga tgatatcggt ttcctgccag
    32101 gagatgagca ggaaaaaatt tctcctcttt taaggccggt aatggataat ttagagcagc
    32161 tgattgattc agatgaagca gacagatatg acgatgaaaa ggaattaaag ggaaaaatag
    32221 aagagatttt tgacagaggg ctgattcagg cggaggcgct gaactttatc aggggccgtt
    32281 cgattgtaaa gacatatttg gtgattgacg aggctcagaa catgacgccc agccaggcaa
    32341 agggaatcat aacaagagcc ggaaaggata caaaagtgat tcttctgggc gacccgaacc
    32401 agatagacag accgtttctg gatgagagaa ccaacggttt aagctacgct tccgagcata
    32461 tgaagggaag tcctctctgc tggcagatca ccatggacgc gtcagagtgc gagcgttctc
    32521 tattggctat ggatgctgcc cgaagaatgt gacgatgaac gaatacagaa gatagaagaa
    32581 aaacaggaga aaacagaaat cagatatgga aaaggaactg acgtacaaag agattcgaaa
    32641 aaataaggag attaatactc ttttagagag gggaaacgag gtgctgggaa gtctgggtta
    32701 cacagaccac tctgctgccc acgccgccaa ggtagctgat acagcaggaa aaattttaga
    32761 gaagctggga tacagtggca gggaggcgga actgagccgg attgcaggct atatgcacga
    32821 tattggaaac agtgtcaacc gctgtgatca tgcccacaca ggagcaatat tagggtggca
    32881 gattctgcgg gagctgggaa tgtctctgaa ggaggcggcg gtggttatgt ctgcagtggg
    32941 caatcacgat gaaaagacag gaactgccgt agatccgatc tcagcggctc tgattctggc
    33001 agataaaacc gatgtgcgca gaaacagggt aagaaataag gtaaaagcat cctttgacgc
    33061 ccatgatcgg gtaaactatg cggcgctgtc ctccaggctg gtgattcaga aggaaaagaa
    33121 ggtgattcag atggaactgg aactggatga ttccatgtgt tctgtcatgg actattttga
    33181 gatcttcctg gaaaggatgc tcatgtgccg gagagcagcc gaggtgttgg gatgcagatt
    33241 caagctgaca gccaacggaa gcaaactgtg ttagaaaaat ttttcaggaa ataaaaagaa
    33301 agagaaaaag acagggccag agagggcgca taccttccca ggctcttctt ttttataata
    33361 tattaaggat tttgtaagcc gtaaacattt actaacgctt ttatctatgc tatattacct
    33421 atagtgcata agtctgccta aaagcaggaa atacgcaggg aacaaagaac tacaaggaga
    33481 gaaatatgaa gggaatcgtt ttagcaggcg gctcaggaac gcgcctgtat ccgcttacaa
    33541 aggtaacatc aaagcagctt ctgcccatct acgacaagcc gatgatctat tatccgatct
    33601 ccgtgctgat gagcgcagga atccgcgaca tcctgatcat ctccacgccg gaggacacgc
    33661 cccggtttca ggagctttta ggagacggac atcagttcgg aattgattta agctatgccg
    33721 ttcagccaag cccggacgga ctggctcagg cctttattat cggcgaggaa tttatcggag
    33781 gcgattcggt agccatgatt ctgggagaca atattttcca gggacagggc cttccgaagc
    33841 gtctcagagc cgcagcggcc aaggagtcgg gagccacggt attcggctac tatgtggatg
    33901 atccggagcg gtttggaatc gtggagttcg atgagaacgg aaaggctgtc tccatcgagg
    33961 agaagccgga gaagcccaag tccaactact gcgtgacagg cctttacttc tacgacaacc
    34021 gggtggtaga gtttgccaaa agcttaaagc cgtccgccag aggcgagctg gagatcacag
    34081 atttaaaccg catttacctg gagaagggcg agctggacgt gattctgtta ggccagggct
    34141 tcacatggct ggacacagga acccatgagt ccttagtgga ggctacgaac tttgtcaaga
    34201 cggtggagac ccaccagcac aggaagattg cctgcctgga ggagatcgcc tacttaaacg
    34261 gctggatcag ccgggaagac gtgatggccg cctacgaggt ttataagaaa aatcagtacg
    34321 gaaagtattt aaaggacgtt ttagacggaa aatatgtaga taagctccat cataactagg
    34381 ataaaaacct gaaatttcag aaattcagaa aaagtcagac aggagaaaca gatatgaaaa
    34441 ttattgtaac aggcggagcc ggctttatcg gcggaaattt tgtgcaccac atggtaaata
    34501 aatacccgga ttatcagatt gtaaacctgg atcttttaac ctacgcaggc aatctggaga
    34561 ccttaaagcc ggtggaggga aagccgaact ataagttcgt aaagggcgac attgccgacc
    34621 gtgagtttat cttccgctta tttgaagagg agaagccgga tgtagtggta aactttgccg
    34681 ctgagagcca tgtagaccgc tccatcacgg atccggagag ctttgtccgc actaacgtaa
    34741 tgggaacaac tactcttctg gacgcctgca aggagtacgg tattaagcgc tatcaccagg
    34801 tatccaccga cgaggtgtac ggcgatcttc cgttagaccg tccggatctg ttctttacag
    34861 aggagacacc gcttcacacg tcaagccctt actcctcctc caaggcagca gcagacctgt
    34921 tcgttttggc ttaccacaga acctacggac ttccggtgac tgtttcccgc tgctccaata
    34981 actacggccc ttatcatttc ccggagaagc tgattcctct tatgatcagc cgtgctctgg
    35041 ctgatgagga gcttcctgtt tacggagacg gcgccaatgt ccgcgactgg ctccacgtat
    35101 ctgaccactg cgaggccatt gacctgatta tccataaagg ccgcgagggc gaggtctaca
    35161 acatcggcgg acacaacgag agaacgaatc tggaggtagt aaagacgatt ctgaaagccc
    35221 tcggcaagcc ggagagctta atcaagtacg taaaggatcg cccaggccac gatcttcgct
    35281 atgccatcga tccaactaag atggagacag agctgggctg ggagccgaag tacaacttcg
    35341 acacaggcat tgcccagacc attcagtggt atctggacaa tcaggactgg tggaagcaca
    35401 tcatcagcgg agagtaccag aattattttg aagaaatgta tggagacaga ttataatgaa
    35461 agtattggtt acaggggtaa agggccagct gggctacgat gtggtaaacg agctgacaaa
    35521 gagaggacat gagtctgtag gcgtggacat tgacgagatg gacattacag acggggaggc
    35581 ctgccgccgt gtgattacag aggcagctcc tgacgcagtg atccactgcg ccgcatatac
    35641 tgcagtagac gcggctgagg ataatgagga tctgtgccgc agagtgaatg cagacggcac
    35701 gagaaacatt gctctggtct gccgggatct ggacatcaag atgatgtata tcagcacaga
    35761 ttatgtgttt aacggacagg gtacgcgtcc ctgggagccg gacgatcaga gagagccgtt
    35821 aagcgtatat ggccagacca agtgcgaggg cgagatggcg gtggaggagc tggtgaagaa
    35881 gttcttcatt gtccgcattg cctgggtatt cggcgtaaac ggaaagaatt tcatcaagac
    35941 tatgctgcgt ctgggccagg agagaggcgc tgtcagcgta gtggacgatc agatcggatc
    36001 tccgacctac acctacgatc tggccagact tctggtggac atgacggagt ccgagcatta
    36061 cggacgttat cacgccacca acgagggact ctgcagctgg tatgaatttg cctgcgagat
    36121 ctttaagcag gcaggcatga cagacgtcaa ggtgacgccg gtagacagct ctcagttccc
    36181 tgctaaggcc aagcgcccca tgaacagccg catggacaag agcaagctgg ccgcaaacgg
    36241 ttttacgccg cttccggcat ggcaggacgc tctgagccgg tatctgaagg agattctgta
    36301 ggagaagagg actgccggga cagagacggg gcggcagaaa cggatgggga tatatctagt
    36361 tgacataaaa caggaggata ggaaacatgg gaaagtattt tggtacagac ggattccgcg
    36421 gcgaggcaaa cgtaacgctg acggtggagg acgcctataa ggtaggccgt ttcctcggct
    36481 ggtattacgg aaagaagaag ccggaggaga aatgccgggt tgtgattgga aaggatacga
    36541 gacgcagcag ctatatgttc gagtattcgc tggtagccgg tctgacagct tcaggggcag
    36601 acgcatacct gctccatgtc accacgactc ccagtgtttc ctatgtggtc cgcacagaag
    36661 aattcagctg cggaattatg atttccgcca gccataaccc attctatgac aatggaatca
    36721 aggtcatcaa tgagaagggt gagaagctgg aagaagaagt tatcacagag attgagaagt
    36781 acctggacgg ggagatggga gagattcctt atgctgtgag agagcagatt ggccgtaccg
    36841 tagactatgc ggcaggaaga aaccgctata tcggctatct gatttccatt gccacccgct
    36901 ccttcaaaaa taagaaggtg ggactggatt gtgccaacgg aagcgcttcc gccattgcca
    36961 agaacgtgtt tgacgctctg ggcgcagaaa ctcatgtgat ccacaacaat ccggacggag
    37021 taaatattaa taccaactgc ggatccaccc atatcgaggg gctgcagaag tacgtggtgg
    37081 agaacggcct ggacgtgggt tttgcctatg acggagacgc tgaccgctgc ctggcagtgg
    37141 acggcgaagg aaacctggtg gacggcgaca agattatgta catctgcgga aagtacatga
    37201 aggagcagag gagtcttgta aacaatacag ttgtcactac gattatgtcc aacttcggcc
    37261 tctataaggc tctggagcgg gaaggaattg cctttgaaaa gacagcggta ggagacaagt
    37321 atgtatatga aaatatgtcc cagaacggcc actgcctggg tggagagcag tcaggacaca
    37381 ttattttcag caagcatgct accacaggag acggaatcct tacctcctta aagattatgg
    37441 aggttatgct ggagaaaaag gaaagtctca agaagctggc tgacgaggta gagatttatc
    37501 ctcaggtgct taaaaatgtg agagttcacg ataagaagac agctcaggat gatccggacg
    37561 ttcaggcgga ggttcagaag gtatcagacg ccctgggaga cacaggacgg attctcctgc
    37621 gccagagcgg cacagagccg gttgtccgcg tgatggtgga ggctgagaca gatgcgatct
    37681 gtgagaaata cgtggatcag gtgattgatg tcatgaaggc cagaggccac gtgatctagg
    37741 agtgaaatca tgcgggagca gctgacaaaa aaggatatcg agaaaattca ggaagagatt
    37801 gactacagaa agctggtggt gagaaaggaa gccatcgaag cggtgaagga ggccagagcc
    37861 cagggggatc tgagcgaaaa ctttgagtat tatgcggcta aaaaggataa gaacagaaat
    37921 gagagccgta tccgctatct ggagaacatg atcaagaatg ccagggtggt gtccgaccag
    37981 tctaaagtgg acgaggtagg cttaaatgat acagtcaccc tctatttcga ggacgacgag
    38041 gaggaggacg tataccgtct ggtgaccagc attcggggca attccctgga aaataaaatc
    38101 agtatcgagt cgcctcttgg aaaagccatc cgcggctgca gagttggaga acgggcctat
    38161 gtaaagataa acgacaaggc cggatactat gtggaaatca ggaagattga gaagacggga
    38221 gacgatggaa cagacgcaat caggagctat taggctccct tatctgctga ctctgcttct
    38281 ggtgaccgtc tgcatgtata cagggtgcct gccaaaaggt ctggcaggtg ccctgattct
    38341 tctgatggtg ctgggagcag ggcttaacac attgggaaat accattccgg tggtgaaaac
    38401 gtatctgggc ggctccgtgg tctgcattct gggggcggcg gccctgcagg cggccggagt
    38461 atttccccag gacgcttatg agatgatgga cagctttgtc aacgagcagg ggtttcttgt
    38521 gttttatatt tctgccctga tcaccggcag tctgtttaat atcgacaggg atctgctgat
    38581 ccgcgctaca gtaaagcttc ttcccacagc gcttatatcc ctggcggcgg gggttctggc
    38641 cacaggagtt ctgggcttct tcatgggaca ttctttttta gagggaattc tttttatcgg
    38701 agtgcccatg acgagcggcg gcatgacggc tggggcggtg ccattatccg gcatgtacgc
    38761 ctcggcgctg ggggctgacg caggggaaat tctcacccgg atcgccccag ctacggttct
    38821 tggaaactgc gtggccattg tatttggagg actggccaat aacctgggag aaaaacggcc
    38881 ttccctcact ggaaacggcc gccttgtcaa cgatggaacc agggccccgg agcggattcc
    38941 catgaagccg tctatcccgc agctctcgaa aggtctgatt atttccctgg cattttatgc
    39001 attgggagcc ctctgcagtc actttatcag cgttgtgccg gcctatgcct ggatgattat
    39061 agctgtggtt atcgtcaagg gaacggggat tttgtcagag gagctggagg acgcggccag
    39121 acagtgggga cagtttgcca tccacagctg gacggcggcg gccctgacgg gaatcggagc
    39181 caccttgatt aatctgaagg ccattatgca gaccatgacg cctttttact tctttaccat
    39241 aacggcgtct gtggcagtaa tcaccatgac ggccgctttt gtgggccgcc tgatgggctt
    39301 ctacccctta gagtctgcga ttgccgccgg catgtgcacc accaatatgg gcggttccgg
    39361 caacgtagcc gtactgagca gcgcgaaacg catggagctt ttgcccttcg cccagatcgt
    39421 cacccgatcc tgcggcgccc tgatgctgac tctggggggc gtgctggtgc agatgttgag
    39481 gtagaaagga gaagcaccct tttaatttgt caaaaatttt aagatcagag agcggagaag
    39541 ataggagcat ggagcagctg aaaacagaaa aaaagctcca aagaggatat ccagaatgct
    39601 gaggagttca aggagaacag acagcagaga ttctgcaaca aacgagtaga caaaccagta
    39661 tattttaaag tagataaaca agtagagtgg tataagcagg agatcaagtc tttttttgct
    39721 gacagaaata gactctttca taaaatttcc tccttgtgca tagtgttaat atcaatatag
    39781 aaggaaatag atgtattgta aaacttgtgc attaaatatt ccatttatcg tggacttcgc
    39841 tgtgcaagcc ttgctgttcc atatctaaga ggaagaaaaa gaaagaagag gaaaactttt
    39901 taagcagttt tcattgaagc accaaaaagt tattcctctc ctaaaaggaa aagaagaaag
    39961 aagaggaaaa ctttttaagc gactttcatt ggagcgtcaa aaagtttttc ctcttctttc
    40021 tcattcatcc tttttcctat cttctctccg caaaagcccc cacacgatca tcagcggaat
    40081 cagacacagc aggctgctct ttatccccag ccatctgctt cccaggaatc cgctgataac
    40141 gccgcagtgg aaggacagca gcgtgccgcc gaagcagatg gcctttttta atttctccct
    40201 ggcccgttct ggattggatt tccgctccag gacgtactct gtcagggaag tgaaggtctg
    40261 cttgatattg ttggtggaga agacgttggc ggcgacaaag tcttccgctc ctgggaaaat
    40321 actccactgg agagcagcgg agaaaaaaat gggatatacg gctgcgatgg gattcatatc
    40381 ttctggaaaa aaactgatgg cagtggcaat agccgcctcc acagccaggg tcaggtattt
    40441 tgccttccgg tgaagctgcc gttccagagg gacagacagg acaagagcag acacaaatac
    40501 cagaaacgcg cccagcctca gcagcgcgtc cggaaaatcg tgccccagga cggcgccgat
    40561 tagttcaatt aaattagcag tctgggcgtt tccaaagacg gacattctgt taaaaaccgc
    40621 ataggagcca aagaagccgc cgcagaacgc catcaggaaa tggatgggca ggccatagga
    40681 tacctgcccc tgttccggtt tcaaaataag ttcctccttt taggaaacaa gagcttcaac
    40741 cttggattcg atttccagta gctgctcctt ggttggaacg tactgaatgc ggatcttgtc
    40801 catgcagatg ttgaagccgc attttacaag ctcttcctcc acctgcgcca cgctctgtcc
    40861 gccccagccg taggaaccga aggcaaaagc ttcccgtttt ttcggggaaa gtcccttcag
    40921 atagcagagg aaagcggcca tgtttggcat catgttgttg tttaaggttg gagagcctgc
    40981 ggcaatatat ttgcagtcca ggacaaatgg caggatgtca gagatgtgct ctgtctttaa
    41041 atctaccaga tgaacgggaa cctgcttccg ggagaagccc tctgcaatgg cctgggccat
    41101 cagctctgtg gagtgccaca tgctgtcgaa tacgaccaga gcgccagtct ccggagtctt
    41161 ggaggaccag gactcatagg cgtctaaaat gtcagctgtg tggcttctcc agataacgcc
    41221 gtggcctgga ataatcatat ccggatttaa ttccttcaca attttccatg cgccggcagc
    41281 ctgggagccg tagcacatga caatgtttgc ataatatttc ttggcctcga acagagtgac
    41341 agccagatcc gtctcgtcat cgaagcggca gctggtgcag tagtgctgtc cgaacgcgtc
    41401 gttggagaag agagccttct cctccgggca ccatacgacc atgttgtcag gccagtggag
    41461 cataggagtc gatataaagg acagggttct ggaaccaata ttcagggaat ctccgctctt
    41521 tacggcctga taggaataat cgccgtagtg ggcagtcagt cccttgatgc cgttaggcgc
    41581 gctggtgaca accgtcgcgt tcgggcatac ctttaaaagc tccggaagag cgccggaatg
    41641 gtccatctcc acatggttgg atacaatgta gtcaatttta gacggatcca ccacatcgct
    41701 gatacgctct aacatctcgg cggcaaaggg agccttcacc gtgtcaatca gagtaatttt
    41761 ctcatctata attaaatagg cgttgtaggt agctccgcgg tttgtcgtgt agccgtggaa
    41821 atttctgatg tgccagtcaa gggcgcctac ccagtaaatg ccttccttta cctgaactgc
    41881 tttcatggtt cattcctcct tatatcaata catggtctaa attttcaaat gtactataat
    41941 ataatttttc cgtgaatgca actgattttc tgcgccgccc agcctcatac agcggaagaa
    42001 cggaaaaaaa tacaagaaat cgttgacaaa actgttatta ctgtatatat tatagatata
    42061 cagtaaatac gaatgatgca gatcatgaat cggcagcaga cgaggatatg gaaccgtgat
    42121 gctgcagaac aggaggccgg agaatgaaca ttgtgatcag caattctggg gaaataccca
    42181 tctatgagca gattgcctcc cagataaaaa acgccgtgat agccggggag gtgaagcctg
    42241 gggagccgct tccgtcgctg agattcttgg ccaaggagct gagagtcagc gtgatttcta
    42301 ctaagagagc gtatgaggag ctggagcggg agggatatat cacgtcagtt ccaggaaagg
    42361 gaagcttcgc cgcagagatc aacagggagc ttctgagaga agaacagtat aagcggctgg
    42421 aggaacattt aaacgaggct gtggacgccg cgcggacggc agggatctcc ctgggggaga
    42481 tgaaggagct gctggaaact ctgtacgaag gatagcttca cagctgaaag gcaaggagga
    42541 ggccggatta tggatttagg agaaaataag aattgggcag agcagacggc gctctcgttt
    42601 gacgcggtgg agaaggcata tggggaattc tgcctgggac cgctgacttt gaagcttccg
    42661 gcaggctgcg tgacagggct tgtaggggaa aacggggccg ggaagacgac gcttatgaag
    42721 ctggcgctgg ggatggttat tccggacaga ggaaccgtat cgtgcttgga ttttgatccg
    42781 gtcagagaag gaaaacaggc gaggaaggat gtgggagttg tctttggaga acttcagatt
    42841 ccaggaaatt ttacggctca gatggcagga gatttctggc aggggattta tgagaacttc
    42901 gacagggatt gctttaagag gcttcaggaa cgctttgcaa ttcctggaaa caagccgatc
    42961 cgccggtttt ctgccggaat gaaggcaaag ctggctctgg caggcgcagt atcccatcat
    43021 ccccggcttt tgattctgga cgaaccgtta agcagtctgg atcctctggc gaaggaggaa
    43081 gcgatggaga tgttaagaga gcttggcggg gaggagattt cgattctgat ttccagccat
    43141 acggtggcgg atttggaaaa gctggccgat tatctggcct ttctccacag tggaaacctg
    43201 ttcctgtttg aggagaagga caggcttctg gaacggtaca gagccgtgca gggaacagaa
    43261 ggagctctga aaggtctgag agaacagaac gtccgtctga ttggaatgag gcggggggcg
    43321 tttggctcct gggcggttct ggataaaacg tcagtccaga gcagggcggt tctggagagc
    43381 ttcggcattt tggaggagcc ggccagtctg gaggagattg taacctgcct gatgagagag
    43441 gagaagtcag gctgcagaga agcatagaga aggaggcggc agaatgaagg ggcttttata
    43501 taaggaattt aaaatgttcg agtgccaggt taagacctgg gcggcagtgc tggtattttt
    43561 actggcctgc gctgtattcg ccggggagac agggcctttt ataggaggga tgtgcggatt
    43621 tatggtaatc agcagcctgt ctccctttac ggaggagagg agaagcggaa gcgacgccta
    43681 cacggcggcc ctccctgtga gccgcagaga gattgtgaag gccagatacg gttttcttct
    43741 gcttctggac acagcggctg cggcagtatt tggcagctgc gccatggccg caggatggtt
    43801 tctgggaaag aactgggaag agacggcgat ggaagtgctg gcagtgctgg gcatttccct
    43861 gatccttcag ctgtttctgc ttccggctgt gtactggctg ggagagatga aggccagagc
    43921 cgcccttctg atttttgtaa tgggcgcagt gtttttgact ctggggctgt cggccggagg
    43981 tctggcggcg acggaggagg ccataaagag gagtattttg tctgctttgc ttctctcggc
    44041 cgttctgctt gccccctcct atcttttgtc tgcgtcagcc atggagaaaa aggagttttg
    44101 acagcgagac agaatgaatg gcagaaacgc gggaaaggct gcgctctgag agcggaggcc
    44161 ggatgcggga agagatcttc ctgtgtccgg cttttttgcg cgtgcagggg aaaaataatt
    44221 agaaaacagt tgacaaatgg gaaaaaagag aatattataa acatatgaac aatcgttcaa
    44281 ttgtttgagc gatatgcagc catgaagaac agaagaagta cagggcagaa gcagaaggga
    44341 ggtttttaag tggcggtaag cgatgtagaa tgctgcgact tttaccaggt ccacgacgat
    44401 gtggtgaagg cggtgaagga aaagatgccg gacgaggacg agctttacga tctggcggaa
    44461 atttttaagg tatttggcga ttccacgaga attaagattc tttatgtatt gtttgaacag
    44521 gagatgtgcg tgtgcgacat tgcccagctg ttaaacatga ctcagtcggc catttcccac
    44581 cagcttaaga ttttaaagca gtcgagactg gtgaaaaaca ggagagaggg aaaagcggtg
    44641 ttttattccc tggcagacgg ccatgtgaga agcattatca atcaggggct tgagcatatt
    44701 gaagagtaga tgtaaagagc agaaaatgga ggaaagcagc tatgaagaaa aaattcaaat
    44761 taacggatct ggactgtgcc aactgcgccg caaagatgga ggcaggcatt aagaaaatcg
    44821 acggcgtgaa ggacgccaca gtgagcttta tgacacagaa gctgaccatt gaggcagacg
    44881 acgagagatt cgacgagatt atgaaggaag ttgcggcagt ctgcaaaaag gtagagccgg
    44941 actgcattat taatatgtag cgtagcgtca ggaggcatca tgacaaagaa acagaaaacc
    45001 atgctggcga gaattatcgc cgcctttctc atttacattc cgctgtttgc cgcttcccat
    45061 aagggggcga tggagggact ttccgctccg gtcaattttg cggtttttct agtcccttat
    45121 cttgtgattg gatgggatat tgtatacaag gctgtccggg ggattgtcaa cgggcaggtg
    45181 tttgacgaaa attttctgat gacgattgcc acctttggag ccttcggcgt cggcgagtat
    45241 tccgaggcag tggcggttat gctgttttac caggtgggag agctgtttca gagctatgca
    45301 gtcagccgct cccgccagtc gattgccgat ttgatggata tctgtccgga gtatgcgaac
    45361 ctggaaaagg acggggagct ggtgcagacg gatccggacg atgtggaaat tggagatatt
    45421 attgtaatta agccgggaga gcgggttcct ttagacggaa cagttatttc aggcgagtcc
    45481 atggtggata cctcggctct gaccggcgag tctgtgccca gaagagtgga gacaggctca
    45541 gagattatca gcggctgcat caatgagagc ggcgttctga gagtggaggt cacgaaggaa
    45601 tttgacgatt ctacggtggc cagaatcctg gagctggtgg agaatgccag cagcaagaag
    45661 gcccaggtgg aaaatttcat cacgcggttt gccagatatt acaccccggc agtggtggct
    45721 gcggctgccc tcctggcggt tgtgcctcct cttgcgctgg gcgcaggctt tggcccctgg
    45781 attcagagag cctgcatttt cctggtgatt tcctgtccct gcgcccttgt tatttccgtt
    45841 cctctaagct ttttcggagg aatcggagcg gcgtccagaa acggcgtcct ggtgaaggga
    45901 agcaattatc tggaagccct ggctcagatg gatacgattg tattcgataa gacgggaact
    45961 ttgaccaagg gagagtttaa ggtaactgaa atccgtccgt ccggcatgag cggggaagag
    46021 cttttaaggc ttgcggctct ggcggaacat tattcaaacc atccgatttc cctctcgatc
    46081 cgggacgcct atgagaaggc gggaggccgg atgaatcttt cctccattgg gaagaatgag
    46141 gaaatttccg gacacggcgt gcggacagag atagacggat ccgtcgtcct ggctggaaac
    46201 ggaaggctga tggaggcgga aaggattgcc tacgaaccgt gcgaaagcat cggaacggtt
    46261 gtgtacctgg ccagggacgg agtgtttgca ggaactatag ttatctctga tacggtaaag
    46321 gagtatgcgg ctcaggcgat ccgcgattta aagcaggctg gcgtgaaacg gacggtgatg
    46381 ctcacaggcg acaggaaggc cgtgggcgag gcggtcgcag agaagctggg actggacgag
    46441 gtcttcacag agctgcttcc ggctgacaag gtagagcagg tggaacggct gttagacggc
    46501 caggcggagg gcagaaagct ggcctttgtg ggagacggca ttaacgacgc tccggtgctg
    46561 accagggctg acattggaat cgccatggga agtatgggat ccgacgctgc catcgaggcg
    46621 gccgacgtgg tgctgatgga cgacgatccg gcccggattt ccgttgtggt gcgcatctcc
    46681 agaaagacac tttccattgt aaagcagaac atcgtcttcg ctttgggggt gaaggccctg
    46741 gtgctgggcc tgggagcgtt tggaatggct aatatgtggg aggcggtatt tgccgatgta
    46801 ggcgtgtccg tcatcgctat tttaaacgcc atgagagcgc tgaagacaaa ataacgcaga
    46861 tttcttccct ctcctcttcg tttacaggag tctgaaaatg tgatagactg aacgcagaac
    46921 tgtgtactgg aggataaagg gatgggaaag acggaagggc tggaacagca ggaaacacaa
    46981 caggcagatc atatctggtg tacttcctgc ggccagattc tgccgaagga atctgtctac
    47041 tgtgaattct gcggttccag gatagagcat gagctggaaa aggcttcagc aggcggagaa
    47101 aaacagcctg aaaagcagaa atcagattct gcatacagaa ctgcatatag aatagaatac
    47161 cgggatgagg agggaggctt tggcttcctg aggcgtccag gatggaaaaa ggccgcggcg
    47221 gctggtatga tggctgcctg tggccttgtt ctgtctgccg tctgggtatc gggcagacag
    47281 gcaggcgaaa agggccagcc tttgctggga tatataaagg ataacagtct gtttatctta
    47341 gaggaaaacg gggagtccag ggagatatct gacatttgtc tgagggactg gaaaaacaga
    47401 gagcagctgc gcctgccgga agctgtggac tggatcccat tttattatga agaggcaggg
    47461 gcgctctggt atccggaaca ggtcggagac ggtgcttttt ccctgatgag cggttccggc
    47521 gggaacgcgc ggaaggcgga cagcagcgca gtttctgttc agactgccgg agagacagct
    47581 gtttatgaaa aggcaaacag cggcctctac ttatacgccg gaggcagaaa gaaaaagctg
    47641 acagccggcg cggcttccta tcagctgtcg gaaaaaggag attatctgat ctggcaggaa
    47701 gaacatccgg atcagacgac agggctttac ggcgtcagcc ttgacaaaaa aggccaggcg
    47761 gcagaggagg agcttttaga gcgggacgca gagtttctgg gcgcttcagg agatttgacc
    47821 aggatccttt acaaaaaaga aggagagctg tggctgcttg aaaatcattc agagaagaaa
    47881 tgcctggcgc agaatgtaaa tcaggtattt ctctcaggcc aggaggaaaa aacgctgttt
    47941 ttcacacggc aggaaaatga gggagagagt ctctatgttc tgagcgggaa acaggcggga
    48001 aacgaaagga cagagcgcct gctggattcg gaattcctgt ttctgatcca tgaggaggat
    48061 ggaattctca cctacaaggc gtccggggaa gccggagagg agatccggat tgccagttca
    48121 gaagcctatg cggcgttaga ctgcaatccg gaagaagaga tttccgttgc ggtttcagga
    48181 gattacggct ggtatttggc ttcgccggag ccaggtgcgg atcaggcgct gtaccgggtg
    48241 tcgcttgaac cggaacagtt tggaagcgca gagcaggcgg cgcagcaggc agatcgtttc
    48301 tgcggacagt gcgggggaac tcccttttat ctgagcgatc tgtatgagca gacgggagat
    48361 ctttactttg gagagcaggc ggtttcctac gatgtgaaag cagattctgt ctggctggaa
    48421 aagaaccggg atggggagga aacggacgtt tattttctgt ctgactatga tgcccagagg
    48481 gaaagcggcg tgctgacaag gtattcgggg gaagacaggc gcgccgaaga gattgacggc
    48541 agcgcatccg ggtatctggc cgtttcagga gaactgctct attttacaga ttacgatccc
    48601 gccagaggcc agggaaccct gaagctctat gaaaagggga agacgcagga ggttgactcc
    48661 ggcgtgtggg ccgcctacgg aagaaacggg gatgaggcgg cttttatccg gaagaaccag
    48721 gctggcggac tggaatagaa cggcatgaca gagaaaaacg gctgttatga aaagaaaaac
    48781 agcaggagag ggagacgaag gagaggaaaa tggcgcagga cagaattgaa aaaataaagc
    48841 tgagtattgg aaagagggcg gcggctttca gccgggcagc agcgctgaag cttgagatac
    48901 accggctgcg cctggaggcc aggactctgc gggccgaagc gcgccagaca gaaaaagaga
    48961 tgcggagggg actttctgag gcttcagaaa aaagctacga ggcctggaaa gagaaagagg
    49021 actggaaaac gcatatggaa gaggcgtttc aggaagccgg agagctggaa gactccataa
    49081 acgcccagag agaggaggcg gcacggctgg aggagacggc cgaggagctg aaatctctcc
    49141 ggagagccga gaaagagacg gcagctgcct cagaagctga gaacagagca gaggaaaatc
    49201 aggaagcgga ggaaaaaaca gacgcagagg cagtctgggt ctgcccttcc tgcggggctg
    49261 cctacgggaa agcggttaat tactgccgcc tctgcggaat ggctgccaaa caagagagta
    49321 aaaagaatcc gggtgaaaaa agccaggaag aagaaaatca aaaggaagaa aaacaagaga
    49381 tagaaaatca agaagaagaa aacagagagg aaggaaatcg agaggaagaa agcagaacgg
    49441 aagaaaagca ggaacctcag gaacgagaat aaaaagaaga gacataattt ttcgaaatgt
    49501 ttaaaaaaac gaaaaagtca tgtctctttc ttcattaaaa gggaacacct ttaaggaaac
    49561 gttccgttac cgcttgttgc tgcgtctcca gatgttcatc ttctcagcgt cggcaatcag
    49621 ctggtctctg aaatcaggat gagcgacgga aatgatagcc gcgcacttct cccaggtgga
    49681 gagtcccttt aagtttacct tgccgtactc agttaccaga tagtggatat tggctcttgt
    49741 gtcagttacg atagagccct ggtttaaggt tggaagaatt ctggatttta actgtccgtc
    49801 ctttgtcttg aaggtggagg aacagcagat aaagcttttt ccgcccttgg aaaggtaagc
    49861 gcccagcacg aagtccagct gtccgccggc tccgctgatg tgcttaacgc ctgcggactc
    49921 tgcgtttacc tggccgaaga gatccacgtc aaccgcgttg ttgatggaca tgaaattgtc
    49981 cagcgcggag atggagcgga tatcgttggt gtagtctacc ggcgcgctca tgcactccgg
    50041 attgttgttc aggtagtcgt agagcttctt ggttcctgct ccgaaggcgt atacctggcg
    50101 tcccttgtca atgcctttgt gagcgcctgt gatctttccg gctgcggcga tatcgacgaa
    50161 agcgtctaca tacatttcag tgtgcacgcc cagatccttt aagtcggatt tggcgatcag
    50221 agagcctact gcgttaggca tgccgccgat tcccagctgc aggcatgcgc cgtctgggat
    50281 ctcctccacg atgagcttgg caaccgcctc gtccacctca gaggcagctc cgcctccgcc
    50341 catctgtccg atggctggat tgtctccctc gatgatcatg tctacattgg aaatgtgaac
    50401 gcagttctca aatccgccca ggcagaccgg catgttttca tttacctcta cgatgactgt
    50461 gtcagccttc tcgcacacag ccgccatgtg ggaggcgttc ggtccgaaat tgaagaagcc
    50521 gtgctcgtcc atgggagctg cctggaacac agctacgttg agaggagtct gggagtcgcg
    50581 gtagtatctt ggaagctcag agtagcggat cggagcgtag aaggagaagc cctgggcgat
    50641 ggcctttctt tcaatgccgc ccatatgcca ggagttccat gtcagatgct ccgccggatt
    50701 ctcaattttg aaaatctccg gaacccacat gaggatgccg ccgcggaaat tcacatcgta
    50761 gagctccggc attctctttg caagagccgc gtcaaaagca acggtcgtgc cagtgcacca
    50821 gccgtagtca acccagtcgc cggactttac cacagcggca gcctgatcgg cagacacaag
    50881 ttttgtttca tacatttttc tgtaatccat ttcaatcacc tgtcccttac aaaatttgtt
    50941 cagttttgtt aacagtttat cattcgccgc tggtaaggtc aataagaata ggtaagaaat
    51001 aggtggaaaa tcgtgaatag gtgatgaatt gataattatt tatcaagtgg tcattgacag
    51061 ttttgcctaa cagtggtagt atagaattac tatcatttat gcaattattt ctatttccag
    51121 gctaaccatg acaaggagga aacaaattat gtctaagaaa gtcgtaatag caagtgcatg
    51181 ccgtacagcc attggttcca tgggcggaca gttaagcaca gtaccagcgg cagatatggg
    51241 agcagttgtt attaaggaag ctctcaacag agcaggagtt gctccggagc aggtagatca
    51301 cgtttacatg ggctgtgtaa tccaggccgg ccttggacag aacgtggctc gtcagatgtc
    51361 catcaaagca gggcttccca tcgaggttcc ggcagttacg ctgaacgtag tgtgcggttc
    51421 cggtttacag tgcgtaaacg cagctgctca gatgattctc gcaggcgacg ctgacattgt
    51481 tgtagcaggc ggagcagaga atatgtccgc agctccgtac gctctgaaga acgctcgtta
    51541 cggataccgc atgggcaacg ctccgatgat cgataccatg gtaaatgacg ctctctggga
    51601 tgctttcaac aactaccaca tgggaatcac agcagagaac atctgcgacg agtggaacat
    51661 cacaagagaa gagcttgacg agttctccgt tgccagccag cacaaggcat gcgaggctgt
    51721 acagtccgga agattcaagg atgagatcgt tccggttgag gttaagaaga aaaaagagac
    51781 tgttatcgtt gacacagacg agggtccgcg tccaggcaca actatggaag gacttgcaaa
    51841 gcttcgtcca gcattcaagc cggacggcgg ccgcgtaaca gcaggaaacg cttcctccat
    51901 caatgacggc gctgcagcag ttgtcgttat gagcgaggag aaggcaaaag agttaggcat
    51961 taagccgatg gctacatggg ttgcaggcgc attaggcggc gtagatccga gaatcatggg
    52021 aatcggcccg gtagcagcta ctaagaaggt tctggctaag acaggactca aggtagagga
    52081 ttttgattta atcgaggcaa acgaggcgtt cgctgcccag tctatcgcag ttgcccgcga
    52141 gcttggattc aataaggacg ttctgaatgt gaacggcgga gctatcgctc tcggacatcc
    52201 ggtaggagca tctggctgcc gtatcctcgt tactctgctt catgagatgc agaagcgcga
    52261 tgcaaagaag ggtctcgcta ctctgtgcat cggcggcggt atgggctgcg ctacaatcgt
    52321 tgagagagac taaaatccag gtaaagcctt aaggagatga tcagaatggg ttatgtagat
    52381 tacgaacagg aaggacatgt cggtattgta actatcaaca ggcccaaagc attaaacgcc
    52441 ttgaatgaag aggtattgaa ggatctggaa accgtattcg acgccattga tcaggagacg
    52501 gtgagagccg tcatcctgac aggcgcaggc gaaaaatcct ttgttgccgg agctgacatt
    52561 gcggctatga gcaccatgac caaagaggag ggagaggcct tcggaaaatt tggaaacgat
    52621 attttccgca agatcgagac cttcccgatt ccggtgattg cagcggtgaa cggtttcgcg
    52681 ctgggaggag gcaacgagct ttccttaagc tgcgacatcc gcatctgctc tgagaacgca
    52741 gtgttcggac agccggaggt aggcctggga atcaccccgg gctttggagg tactcagaga
    52801 cttgcccgca tcattggtgt gggaaaggcc aaggagatgc tctacacagc cagaaacatc
    52861 aaggctgatg aggcttaccg tttaggactt gtaaatgcag tttatcctca ggaagagctg
    52921 atgactgcag ccagaaagct ggcaggccag attgcggcta atgctccgat tgctgtgaga
    52981 aacagcaaga aggcggccaa tgacggcctt cagacagata tggatcaggc gattgtaatc
    53041 gaggaaaagc tgttcggagc ctgctttgag acagaggatc aaaaagaagg catggcggcg
    53101 tttcttgaga agagaaaaga aaaacagttc aaaaaccgtt aataaaaagc agatgctttt
    53161 tataagatag gaggagatag ccatgaaaat cggtgttatc ggagcaggaa ccatgggttc
    53221 cggcattgcg caggcttttg cacagacaga gggctacgag gtagctttat gcgatattaa
    53281 cgaggagttc gctgcaaacg gtaagaagaa aattgcaaag ggctttgaga agagaattgc
    53341 taagggcaaa atgacacagg aggatgctga taagatcctc gcaaagatta caacaggtgt
    53401 taaggatatc tgcggcgact gcgatctggt cgttgaggct gccattgaga acatggagat
    53461 caagaagcag acctttaagg agttagacgc tatctgcaag gcagactgta tttttgctac
    53521 caacacttcc tccctctcca ttacagaaat tggagcaggc gcaagaccgg ttgtgggcat
    53581 gcatttcttt aacccggctc ctgtcatgaa gctggtagag gtaattgcag gactcaatac
    53641 tccgaaggag atggtagata aggtaattgc tatttccgaa gagattggaa agacaccagt
    53701 acaggttgaa gagggtgcag gctttgttgt aaatagaatc ctgatcccga tgatcaacga
    53761 ggcaatcggc atttacgctg atggcattgc atctgtagag ggaattgata ttgcgatgaa
    53821 gttaggcgca aatcatccga tgggcccgtt agctctgggc gatctgattg gacttgacgt
    53881 ttgcctggct attatgcagg tattagaaag cgagacaggc gatccgaagt accgtccgca
    53941 tccgctgtta agaaagatgg ttcgcgctgg acgtttaggc cagaaaacag gcagaggatt
    54001 ctacgattac agcaaataat ggataccact tttttgtggt ttctgttata atagattcac
    54061 aaccgcataa ggggtctccc caaggcccct ttttagcgcg atataagaag atggaggact
    54121 agacatggat tttacattaa gtaaagagca tgagatggcg aggactttat tccatgactt
    54181 cgccgagaaa gaagtaaaac ctttagcaca ggaagtagac gagacagagc acttcccgac
    54241 agagacagtt aagaagatgc agaagctcgg cttcatgggc atcccggttc cgaaggagta
    54301 cggcggacag ggctgcgatc ctctctgcta tgctatgtgc gtagaggagc tttccaaggt
    54361 ttgcggaact acaggcgtta tcgtttctgc acacacatcc ctgtgctgcg atccaatcca
    54421 gacatacggt acagaagagc agaagcagaa atacctggta ccgcttgcaa agggcgagaa
    54481 gttaggtgct ttcggtctta ctgagccagg cgctggtaca gacgctcagg gccagcagac
    54541 aaaggctgtt ttagacggag acgagtgggt attaaacgga tccaagatct tcatcacaaa
    54601 cggtaaagag gctgacatct acgtaatcat cgctgttaca ggcgtgaaag aggacgctag
    54661 aggaagaaag aagaaagaga tctccgcatt catcgttgag aagggaactc caggcttcac
    54721 ctttggtaca aaggagaaga agatgggtat ccgcggatct gctacttacg agttaatctt
    54781 cacagactgc cgcatcccga aggagaacct gttaggacag aagggcaagg gcttcaacat
    54841 cgctatgcac acactggacg gtggacgtat cggtatcgct gctcaggctc ttggtcttgc
    54901 agagggcgct cttgacagaa ctatcgagta tgtaaaagag agaaagcagt tcggacgtgc
    54961 tctgggacag ttccagaata cacagttcca gcttgctgat atggcaacaa aggtaaaggc
    55021 agctcagctc cttgtttaca gagcagctat ggctaaggct acacagaaga catattccgt
    55081 agaggcagct atggctaagc tgtacgcagc agaggttgct atggaagtta caacaaaggc
    55141 tgtacagctt cacggcggat acggctacat cagagagtac gatgtagagc gtatgatgcg
    55201 cgacgctaag attacagaga tctacgaggg aacatctgag gttcagagaa tggttatctc
    55261 cggagctctg ttaaaataat tgcggctcta aacatgatgc agttccctgt ctctttggac
    55321 aggcctgcat gaaattaaac aataaggagt gaaaatacag tgaaaattat cgtttgtatc
    55381 aaacaggttc cagatactaa gggcggagta aaattcaacc cggacggaac actcgacaga
    55441 ggagctatgc tcacaattat gaacccggat gataaggcag gccttgaggc tgctctccgt
    55501 ttaaaggatc agtacggcgc agaggttaca gttctcacta tgggacttcc gaaagctgag
    55561 gaggttttaa gagaggctat ggctatgggc gctgacaacg gcatcctggt tacagaccgc
    55621 gtacttggcg gagccgatac atgggctaca tcccagacta tcgcaggcgc tatcagaaac
    55681 cttgagtacg atttaattat cacaggccgt caggctatcg atggtgatac agctcaggta
    55741 ggtccgcaga tctccgagca cttaaacatt ccggtaatca gctacgctca ggacatcaag
    55801 atcgagggca acagcgttat cgttgagcgt cagtacgacg acagatatca cgtattaaag
    55861 gctcagatgc catgcttaat cacagctctg gctgagttaa acgagccgcg ctacatgact
    55921 ccaggcggaa tcttcgatgc ttataagaaa gaaatcaccg tatggggaag aaacgacctg
    55981 aaggacgttg aggactccaa cttaggactt aagggatccc cgacacagat cgcaagagct
    56041 tccgataagg taagaaaggg agcaggcgag caggttactc ttgatccggc agcagctgca
    56101 gactacattg ttgagaagct ggcagctaaa catgttatct aattaaaaat aagagaaaag
    56161 tgtggtgaat agaatgaact tagaagcata taagggagta ttcgtctttg cacagcaggt
    56221 tgacaatgag atcagcggca tcgcatttga gctgattggc aaaggtaaag atttagcaaa
    56281 agatttagga acagaggtta cagctgtttt agttggttcc ggcgttaagg gactggcaga
    56341 cgagctggct gagtacggcg cagacaaggt tatcgttgta gacgatccag agttaaaaga
    56401 gtacagaaca gagccgtaca cacacgcact ggcttccgtt atcaacgagt ttaagccgga
    56461 gatcttctta atcggcgcta cagcaatcgg ccgtgactta ggacctcgtg tatgtgcaag
    56521 aattcataca ggtctgacag ctgactgtac acagcttgag attggcgatt tcccaatcaa
    56581 cccggttcca ggcaaggagc agaagcacaa ccagttatta atgactcgtc cagcattcgg
    56641 cggaaacaca atcgctacta tcgcatgccc ggacttccgc ccacagatgg caactgtacg
    56701 tccaggcgtt atgcagaagc ttcctaagac agcaggcgct aaggctaacg tagtagagta
    56761 caatccagga ttcgttccga acaacaacta cgttgagatc atggaagtag ttaaggctgt
    56821 agctgataca gtagacatta tggacgctaa gatccttgta tccggcggac gtggtgttgg
    56881 aagcccagag aacttcaaga ttcttgagga tctggcagag gtaatcggcg gaacagtaag
    56941 ctgctcccgt gcagttgtag acgctggctg gcagccaaag gcattacagg taggacagac
    57001 aggaaagact gtacgtccga acgtatactt cgcaatcggt atctctggcg ctatccagca
    57061 cgtagctggt atggaggagt ctgatattat catcgctatc aataaggatg agacagctcc
    57121 gatctttgac gtagctgact acggcattgt aggtgacctg aataaggtag ttccgttatt
    57181 aacagagaag ctgaaagctg ctaaggctgc tcagaacgtt taatctgaac ggaaatttta
    57241 taatagaata aataatcgtc cgggggacgg cagtccgcat gattacgtca tacggccagg
    57301 ccctcctacg ccggacggcg tccttacgaa cgcgagaggg acgcagtgcc cagacatcaa
    57361 aacagcccgg caaaagccgg gctgttttga tgtggaagaa agacttcgca ggctttaaga
    57421 gaaacaagaa gtctttattc agttcgtttt ttctctttga tgtggaagaa agattttgca
    57481 gacttcaagg agaacaaaaa gtttttttca gttcgttttc tccctttaaa gtggaagaaa
    57541 ggttttgcag acttcaagcg aaataagaaa tttttcttca gctcttctct ttaatgtgga
    57601 agaaagattt cggtgacttt aagtggaaca agaaatcttt cttccacatt tatccatcac
    57661 ctttaaatcc acccaccgtc cagtccgatg acctgtccag tcagatagct ctccttatat
    57721 cccaggtggt aggccagatc ggccacctcc tcggcctggc ccagacggcc cgccggaatt
    57781 tcttcaatga ggccgataag ctcctcgtcg tccaggaagt gattcatctc cgtatcaatg
    57841 gcgccgcagg caatggcgtt gacctggata tggctggggg ccagttcctt ggccagagct
    57901 ttggtgaagg cgttgatgcc gcccttggta gcggagtagg ccacctcgca ggaagcgccg
    57961 cagattcccc agacagagga aatgtttatg atctttccct gctgcttttc caccatcatg
    58021 ggcacggcca gccggcagca gttgaataca gaggtgagat tggtgtgcac aatcaggtcc
    58081 cagtcctctg gcttcatatc ctggagaagt ccgatgtagg agattcccgc attgttgaca
    58141 agcacgtcca gcccgccgaa ctgctttttg attttcttga atagagcggc gcagtcctcc
    58201 atctttccca tatctcccag aaaagccaga caggatacct ggaaggattc aatttctttc
    58261 tttgtctgaa gaagctgttc ctcccgcttt acgcagctga tgactacatt ccagcccttt
    58321 ttggcaaatt tcacggcgat ggctttcccg attccgcggg aagcaccggt gacaagtaca
    58381 gtttttcttg ccatataatt tcactccttt cccaaacaaa cgctgcttaa ctttctctga
    58441 ccatattata ccattgacgg attgacagtg caaatttata gattaaataa aaaattatgt
    58501 atactgccgg gataagatgt gttatactaa aaagtacgaa tacaacacag aagaacaccg
    58561 gcttttgggc gggaacagga tgggaaacac ttggaacgta cgaatctgcg gcctgcagat
    58621 tccagaggaa aggcgagaat aacaggatgg gaaagattta cgatctgatt attgcaggtt
    58681 ccggcccagc cggactggcg gcggcaatct atgccaaaag ggcggaactc gacacgcttg
    58741 taattgagaa ggagatgatg agcggcggcc agattctgag tacctatgag gtggacaact
    58801 acccaggact gccgggaagc tcgggatttg atctgggaat gaaattcagg gagcatgcgg
    58861 atcggctggg agctgttttt acagaagact gcattgagaa ggcagagctt ctcggagaga
    58921 ttaaaacact ctatggacaa aaggaaacct accaggccag gacggtgatc atcgccacag
    58981 gagccagcca cagaaaactg ggcattccgg gcgaggagga gcttttgggg agcggagttt
    59041 cctactgcgc tacctgtgac ggcgcctttt tcaaggataa gacggcggct gtgataggag
    59101 gcggggacgt ggcccttgag gacgccattt tcctgtctag actgtgcaga aaggtccatt
    59161 taattcacag aagggacgag ctgcgcggcg ccaggacgct gcagaagcag gtgtttgaat
    59221 cagataagat agaagtgcac tgggacacag tggcagacgc cattgagggg gacggcagag
    59281 tcgagagact tgcgcttacc aacagaaaaa caggggagaa gacggcgctt gagacggacg
    59341 gcgtatttat cgccgtagga attgaaccgg aaagcggcct gttttcccag atgatagaga
    59401 cagaccgcca gggatatctt gcggccgggg aggacggagt tacctctgtt cccggcgtgt
    59461 tcgcggcagg ggatgtgcgg accaagcagc tgcgtcaggt gctgacagcc gcatcggacg
    59521 gggctaactg cgtgaccagc gtggagcggt acctggcaga gagataggag gaagaaatac
    59581 gatggagacg ccatttaaga tactggcctg tctgtgctcg gcagccgtca tttccgtgac
    59641 atcaggcttt ggagcgcagg cggcgatcaa tctggagaca gattcttctg tagctggagt
    59701 ttccgtggcg atgaataatt attatgcagg aagccttgat ccggagaacg agctggcgga
    59761 ggctttttcc tcagatgaaa ccatggaaca ggtggtaaag agcgggaagg aagacgcgcc
    59821 gacagtaaag aatccgtcgt cctcctccgc ctatgataac gtagcggtgt cccaggtgtc
    59881 caattatgta aacgtgcgga gcgaggccag cacaaagggt tctgttgagg gaaagattta
    59941 caacaactgt gcggccacga ttctggatac agtggacggc gagggaggaa agtggtacaa
    60001 gatccagtcc ggttctgtaa acggctatat taaggctcag tattttatca caggagcaga
    60061 ggcggagaag aaagccagac aggtgggaac gacttatgcc aaggtggcga atacctccac
    60121 gctgcgcctc agagaggagc cgagcctgga cagcaagaca cttgatcttc tgtcctcaga
    60181 cgctgagtat gaagtaattg aggaaaaggg agacttttat aaggtgtctg tggacacaga
    60241 tctggtagga tatgtgttca aggattacgt cgatacccgg gttgaatttg accacgccgt
    60301 gacaaactca gaggaggagc agaaggcggc ggaggagtcc aagcgcaagg aagaggcgga
    60361 gaaggcactg caggagctgg aggaggccaa gaaggaagcc gccaaggaga ccactgcaaa
    60421 agagactgcc gccaagcaga ctgcagcgaa agaaactacg gccaaagaaa cggtgaaaga
    60481 gcctgagacg gtaaagccga aggaaacaga gaaagccaaa gagacggaaa cgtcgttcag
    60541 cggtacgata gagcagaatc cggacggaag cccgagggag accacgaagg ctgccgagac
    60601 aaagccgaag gagacagaga aggaaaagga gaccacaaaa gctcctgaga cagaaaagcc
    60661 aaaggaaacg cagaaaccgt cctctgataa gacgtctgga ggtcccggcg gatctaagaa
    60721 tccaggaggc agctcctcag gagtggagaa ggccaccaga acggcggttg tcgcttatgc
    60781 gaagcagttt ttgggaaatc cgtatgttta cggcggaacc agcctgacca agggagcaga
    60841 ctgctctgga tttacacagg ccgtgtacgc ccatttcggc atctctacag gccgcagctc
    60901 cagagaccag gctgccagag gaaaggagat tccggtaagc gaggctcagc cgggcgatat
    60961 gctgttctat gccagcggaa gctatattaa ccatgtggct atgtacatag gaggcggaca
    61021 gattatccac tccagcaacc ccaagacagg aatctgcatc gcgccgtcca actacaggac
    61081 gccgtgcaag gctgtcacct tcctggatta gaacgctgga agagaagaag gcagatagaa
    61141 gaagacggag aaaaaagaga caaaaaaaga ttaaaaaata aggcaggacc cgtaaaagga
    61201 gaacagccgt aaaaacgggc cggcgcaggg agatttccag gcgccggccc gtttgctgac
    61261 taatcttcag ttttctttag atgttccgtt tcgggaaacg gtttctgggt aaaataggtg
    61321 gacaaaagaa cggacgtatt ggagaggccg aactgccgca tctgccggag caacgcttcc
    61381 agctcctcgg aatcagagac ccggattttt aaaagcccgt tattcagtcc cacaatgtgg
    61441 ctgtgctcca caatagacgg cgtttcctcg cagaatctgc agaaactttc gtaggattta
    61501 gggggcacgt tgatcaggac aaaggcacag atgtgattac ccatcagggc gtcgttgatt
    61561 ttggcatgga atccctcgat cactcccgcg tccttcagac ggttaatccg ctcggcgact
    61621 gccggcgcag taagcccgac ctgctgtccg atctcgcggg tcgacgtttt gcagtttgcc
    61681 tgcagaatgt tgatgatttt aatatctgtg ttgtccacgg ggctccctcc cttgcagatg
    61741 atctctaaac tataatagta tagccgatag tgagaaaaaa gtaaatggaa tctgtaagcc
    61801 cgatgacaga ttcagaaggc ctttgttagg aaaatgaaga ttcattctga gtgaaagagc
    61861 tgtacaacaa caggggattg atggtaaaat tatcgtacaa tacaaaaagg aatgcgaaga
    61921 caggcataaa aaagtaaaac agaactggga ggtaagagtt ttatgagcgg aaagttattg
    61981 gaatgtgtgc cgaattacag cgagggacgc gatatgcaga aggtggagca gattgcagac
    62041 tgcttccgcg gaaaggctgg ggtgcggctt ttagattatc agacggacaa agatcacaac
    62101 cggtgcgtga ttacggccat cggagagccg gaggctctgc gggacgctgt gattgaatcc
    62161 tttggaaagg cggttcagct gattgatatg acgaagcacg agggacagca tccgaggatg
    62221 ggagctgtgg acgtggttcc gtttattcca tgcaggaata cgacgcttca ggaggccgac
    62281 gccattgcca aggaggtagc tgagacggta ggcagagagt tcggcattcc ctgcttcctg
    62341 tacgagtcct ccgccattgc tcctcaccgc gccaatctgg caagtatccg gaagggacag
    62401 tttgagggga tggcggaaaa aatgaaggat caggagatgt ggaagccaga tttcggtccg
    62461 gataccattc acccgacggc aggcgtatcg gcggtagggg ccagaatgcc gttagtagcc
    62521 tttaatgtga acctggacac agcggatctg gagattgcca atcagattgc caaaaagata
    62581 cgccacatca acggcggcta ccgctatgtg aaggccatcg gagtcatgct ggaggagaga
    62641 cacattgccc aggtttccat gaacctgacc gattacacga agacggccat ttaccgcgcc
    62701 tttgaggcag tgaagatgga ggcaagacgc tatggcgtga gagctgtggg tacggagatt
    62761 gtaggtcttc ttcccatgca ggctctgatt gactgcgcgg agtattacat gcagctggag
    62821 aattttgact ctgcccaggt aatggaaaac agacttcttg aggaggaata agatgacaga
    62881 attaaaggat ttgaccatag aggaatttgc aaaggtgacg gcgtccgacg ccccggctcc
    62941 gggaggcgga agcgtggcgg cggcagcagg ctccctggct gccgcccttg ccgagatggt
    63001 ggctaacctg actatcggga aggaaaaata tgcggaagca gaaaatgaga tgagagagct
    63061 ggctgagaag ggccaggcga tccgtgagaa gctgatagca gatatccaga gagacagctc
    63121 ttcttttaac ctttacatgg cggctttaag aatgccaaag gacacagaag aagaaaaggc
    63181 ggccaggaga gaggccatgc agaggggatt aaaggaggcc gctgtggttc ccctttccgt
    63241 ggcagagacg gcggctgaaa ttttccctct ggccgaagcc gctgtggcca ggggaaacgc
    63301 caatgcggtg acggacggcc tggtatctgc catgatggcc cgcactgccg ttctgagcgc
    63361 tcttttaaat gtcaaaatta atctgaactc catcaaggac gaagccttcc gggcagatat
    63421 ggagaagcag gtgaaaggcc tggagaaaac ggcgtctgag tacgaggcga agatattaaa
    63481 aagttcagag ctttctcctg aaatataaaa ataaactgct aagactttaa aactttaaaa
    63541 aattaagaaa aaataggatt gcattttaca aaaataaagg atagaatgga aaaatgcaga
    63601 tgaatcagaa gtcagcatca tttttagtag gaggagaacg aagatgaaaa cagatatcga
    63661 gatcgctcag gagtcaaccc cattacatat cacagagata gcagcctctc tgggtattga
    63721 cgaaaagtat ctggaacagt atggaaagta caaggcaaag gtagactata acctgttgaa
    63781 cgaggacagc cgccccgatg gaaagctgat tcttgtgaca gccattactc cgactcctgc
    63841 tggggaggga aagactacga ctaccgtagg cctggcagat ggaatgaaga agctggggaa
    63901 aaatgtagtt gtggccctca gagagccgtc tctgggaccg gtattcggcg tgaagggcgg
    63961 cgctgcaggc ggcggttatg cccaggtagt gccgatggag gacattaacc ttcactttac
    64021 cggcgatttc cacgctatcg gagctgcgaa caatcttctg gccgctatgc tggacaacca
    64081 catttatcag ggcaacgagt tgcggattga cccgaagcgc gttacctggc gccgcgtcgt
    64141 ggatatgaat gacagacagc tgagaaacgt ggtggacgga ctgggacgcc gcgtggacgg
    64201 agtggtgaga gaggacggat acgatattac agttgcctcc gagatcatgg cggttctctg
    64261 cctggctaaa aatgtaactg acttaaagga gagactgagc cgcattatcg taggctacac
    64321 ctacgacgac gagccggtga cagcgggaga tttaaaggct gccggagcga tggcagctct
    64381 gttaaaggat gctttaaagc cgaacctggt gcagactctg gagcatactc cggcctttat
    64441 tcatggcggc ccgtttgcca atatcgccca cggctgcaac tcgattatcg ctaccagaat
    64501 ggccttaaag ctgggagatt acgcgattac agaggcaggc ttcggcgcag atctgggcgc
    64561 tgagaagttc ctggatatca agtgccgcat ggcagagctg aagccgtcag ctgttgttgt
    64621 ggtagctact gtcagagcct taaagcatca cggaggcgtg gctaaggcag atctgaacaa
    64681 cgagaatctg gaggctctgg agaagggact tccgaacctg cttcagcatg tggagaatat
    64741 cacgaaagta ttcggcctgc cctgcgtagt agcgattaac cgcttcccat tcgatacgga
    64801 ggcagagctt tctctcattg cggaaaaatg cagggagctg ggcgttaacg tggcgctttc
    64861 cgaggtatgg ggaaaaggcg gcgacggcgg cacagagctg gcccaggagg tgctccgtct
    64921 ctgcgaggag ccgaaccact tccagttctg ctatgactct gaactctcga ttgaggagaa
    64981 gttaaacgca attgttacca aggtatacag aggagctaag gtagtgctgg cagattctgc
    65041 taaaaagcag gctaagagac tgacggagct gggctttggt tcctgcccga tctgtatggc
    65101 caaaacgcag tacagctttt ctgacaacca gaagctttta ggagcgccga gagactttac
    65161 tgtgacagtc agaaacttaa aggtatctgc cggagcaggc tttatcgtag ccctgacggg
    65221 agatattatg actatgccag gccttccgaa ggttccggca gcagaaaaga ttgacgtgga
    65281 tgctgaggga agaatctcag gcttattcta aaccataaaa gtacaaattc cgccgcaggg
    65341 gaatggttcc tctgcggcgt cttgtgtctg tcacagcgtt ttgtcaggag gaagtaacat
    65401 gaatttcttt acaccagcgg aaatcgtaaa aaattatggg gcggcaggaa agaaaaaggc
    65461 tgagatgcct ctgttaaaaa tgcttattct gggttttctc tcaggaatgt tcattgctct
    65521 gggagcggcg gtgaccaata cggccggaca cagcattgac aatgtgtcgg ccgtccggat
    65581 tctctctgga cttctgtttc ccggaggcct gactctggta gttttgatgg gaggagagct
    65641 ttttacagga aactgcctga tgtgtatttc tgttctggag aagcaggcga agctttcagg
    65701 cgttctgaaa aactgggccg ctgtctatgt gggaaacctg gccggaagcc tgtttatcgc
    65761 cttcgcctgc gcaaaattcg gccagatgaa ctactctggc ggagggctgg ccgtatttac
    65821 catgaagctg gccgcctcca aatgttctct gccttttgaa aacgcctttg tgctgggcgt
    65881 gttctgcaat atcctggtat gttttgcagt actggccgcc atgagcgcca aggacacggc
    65941 gggaaaggtg ctggggctgt tttttcccat ctgctttttc gttgtatgcg gatttgagca
    66001 cagtgtggcc aatatgtact acattccggc gggaatcttc gcctcttctg tgccggagta
    66061 cgcggccggg gctttggagg cgggagtcga tctttccgtc ctgacctggg gaaatttctt
    66121 cctgaaaaat ctgcttcccg tcaccttggg aaacattgcg ggaggcgtgc ttacaggcag
    66181 ctttatgtgg ctgggccatg tgtgggagaa aaagaaatag aataaaaaga aaagacgccg
    66241 ggcacggggg gtatccgtat ccggcgtctt ttccggacgc tggcaaatcg tcgtttgata
    66301 tactttgatc aatgagttac ttgttctgct cctcctcgca gttcatgttg ttgagagagc
    66361 aggacatgtc gtcttttcca tcgacacagt tcatgtcgtt taaaccgcaa ctggagtcgt
    66421 catcctctcc caggcagttc atgtcgttta agccgcaggt tttgtcgtcg tcgctgatgc
    66481 cgttcaggtt agaccatccg ctctgttttt tctcctccat atcccatacc tcctccaagt
    66541 ttagtaattt tattatatcc ggggccagag gaaaattcaa ggaggagtca ggcgggaaaa
    66601 gcgggaattt caggaggaat ttgacagttt gaaaggattg tacagaagga acgggaacgg
    66661 atggtttctt tcgtctgctc agttgctttt ccctgtgcct gccgctataa ttgagataga
    66721 aaggctggcc ggatgcggca atgccggaca gagtaagcgc gcaaggcaca ggaaagtaca
    66781 gggaggagag agaacatgag ccggaaactg acagaacaaa ttccaagtga aagccgtctt
    66841 gtagacgcag ctttaaaaga gaatctgaaa actatttttg aacggctgga gaggccgctc
    66901 tgtctgaagg cggttttaga accggatcag agagagtgta cagagatggg agcctttttg
    66961 aaggctgtgg ctgaacttag cccgatgctt gagattcagc ttctggagaa gggagaggac
    67021 ccgcaggctg accgggagct ggacacagcg catctgccgg ttacgggact gtaccaggaa
    67081 ggggagtacc tgggcgcggc tttctgcgga gtgccgggag gaaaggagat caattcgttt
    67141 gtttccgcta ttttgaacgc agcggggcca aagaaggaat atgatgaaaa aattctcaaa
    67201 aaattgggaa agctgaagaa aaagaacgtg atccgcgtat gcgtttccct gtcctgccac
    67261 cactgccaga gcgtagtgac tgctggacag accctggccc ttttaagccc taatgtggag
    67321 tgcatcatga ttgatgccag actgtacccg gatctggtgg aacagtataa gctgtctcgc
    67381 gtgccggctg ttttgatagg agaggcgctc tatatgggag agaaggacat ggaggagctg
    67441 ctggctctcc tcaggtagaa agaagaggcc tgcaggatgg aaaaagaaga aattggtgaa
    67501 aaggctgtgg ttttttgaag aattctgtaa tttttgcaca aaacggatga gaaaaagaac
    67561 tggacgcaga attggttgtg caaaaatgat aataatataa cgatatattg acttatattg
    67621 tataatatgt taggattctc ttagttgaat atgaaccagg agagaggagc aggtggataa
    67681 cggcagaaat gccgcttatt gaatctgctc tttttttcct ttataggagg cgtttacacc
    67741 ctgtaaaagg aaaaacgttc cgccgcgtca gcacggaatt gattcatacc agcagtttta
    67801 aggaaggtga agcatggagc agaaacttta cgataccgtg acagattgtc cggtgattgc
    67861 ggcgattaag gatgacgcag ggctggaacg gtgcctggat tcagacatac agatcgtctt
    67921 tgtgctgtac ggcgacattg tcagcatacc ggaaattgta gacagaatta agaaaaaagg
    67981 aaagctggcc atggtgcacg cagacctgat atcaggtctg gcggggaagg agatagccat
    68041 tgatttcctg aagaggaata ctcaggccga tggaattatt tccacgaagc tgtcatttat
    68101 taaaagagcg aaggaattgg gtatggctac agtgttccga ttttttgtga ttgattccat
    68161 ggcgtttgac aacattcaga agcagtatga ggcggcctgt ccggactttg tagagattct
    68221 tccgggaatt atgccgaaaa ttattgcgaa ggtagctaaa atggtatccg cgcctgtgat
    68281 tgcaggcggt ttaattgcgg agaaggcgga catctacgcg gctatagagg ccggagccat
    68341 ttccatctca tccacaaatc agaatacctg gtttatctaa gagaggggga gacggatgtc
    68401 agatacaaaa agaaaaatgg cccaggcttt gaaggagctt atggcggaga agccgttaaa
    68461 acgaattacc attcaggata ttgtggagag aagccacatg acgcgccaga gcttttacta
    68521 ccattttcag gatatctacg aggtgctgga gcttatctgc cgatacgatc tggtggatca
    68581 gatcgcttac cgggaggagg agagcttcgc ccactggatg gagcgcctga tggagattgt
    68641 ggagacgaat aagtggtttt acaggaagat gcttcaggat atggactggg agagagtagc
    68701 cggttatctg aagccggcgg tggaggcgca gattcgccgt ctggtatcag ggatgctgac
    68761 agagcaggag acgcggagcc tgtcaggagg ccgggagctg ctgatcgatt tcctcacagt
    68821 ctctgtgatt cagtacatct tccgttacat ttccagccgg aaggttcaga aggagcagaa
    68881 tgccgccagt ctccgggaac tgcttcaaat ctgctcgctg ctctgcgcca agtgcagctc
    68941 ttcgtctgaa aataaagatg aagtatacat taaaaacagg ataaagacgg cttaagaaga
    69001 atttgtttta acaaataaga actattgtct aaagacattt gacaataaag gtgatactat
    69061 aaatgcatat catgtaagga ggggtttctt atggcaaagt atgtaatggc attggacgct
    69121 ggaacaacca gcaacagatg tatcctgttt aacgagaagg gtgaaatgtg cagcgtggca
    69181 cagaaggagt ttacacagta ttttccgaag ccaggctggg ttgagcacaa tgcaaacgaa
    69241 atctggtcct ctcagctttc cgtagcagtt gaggctatgg ctcagatcgg agcgaacgca
    69301 gaagatatcg ccgcaatcgg tattacaaat cagcgtgaga ctacgattgt ctgggataaa
    69361 atgacaggag agccggtata caatgcgatt gtgtggcagt gccgccgtac ctccgaatac
    69421 tgcgattccc tgaaggaaaa gggactgaca gacaaattca gagagaaaac aggtcttgta
    69481 atcgacgcat acttctccgg aaccaagtta aaatggattc tggacaacgt gccgggcgta
    69541 agagagagag cagagaaggg cgagctctta ttcggtaccg ttgagacctg gctgatctgg
    69601 aagctgacca agggctctgt tcatgtaaca gactactcca acgcatccag aacgatgctg
    69661 tttaacatca atactttaca gtgggacgac gagatcctgg ctgagttaaa tattccgaag
    69721 tgcatgcttc ctgaggcaaa gccgtccagc tgcgtttacg gcgagtccga tccggtcttc
    69781 ttcggcggcc cgattaagat tgcaggagct gcaggagatc agcagtccgc tctgttcgga
    69841 cagacctgct tcaatcctgg cgaggctaag aatacatacg gaaccggctg cttcatgctg
    69901 atgaacacag gcgagaagcc ggtattctcc aagaacggcc ttgttacaac tatcgcctgg
    69961 ggacttgacg gaaaggttaa ctatgcgtta gagggttcta ttttcgtagc cggcgcttct
    70021 atccagtggc tgagagacga gatgagactc attgattcct caccggattc cgagtacatg
    70081 gccaagaagg taaaggatac aaacggctgc tacgtggttc cggccttcac aggactgggc
    70141 gctccgcact gggatcagta cgcaagagga accatcgtag gaattacaag aggcgtaaac
    70201 aaataccaca ttatccgcgc gacactggaa tctctggcat accagaccaa cgacgtactg
    70261 caggcaatgc aggctgactc cggcatccag ctggaagctc tgaaggtaga tggaggcgcc
    70321 agcgcaaaca acctgttaat gcagattcag tctgatatta tccaggctcc tgttcatcgt
    70381 ccgaaatgcg tagagactac agctatgggc gccgcttatc tggcaggtct ggcagtagga
    70441 tactgggcaa gcaaggaaga cgttattaag aactgggcca ttgaccgcgt attcgctcct
    70501 gagattgaac cagaggagag agataagaag gttaagggct ggaataaggc tgtgaagtgt
    70561 tccttcggct gggctaagga agattaatcg gcagtaagag acatcgatcg gataatagaa
    70621 aagggggaat ttttatgctg ccatatatag ctgaattttt gggaaccatg atgctgatcc
    70681 ttctgggcga cggcgttgta gcaaacgtaa acttgaataa atccggtatg aagggcggag
    70741 gatccatcca gattaccttt gcatggggcc ttgcagttat ggttccggca tttatcttcg
    70801 gcgcagcttc cggcgcttcc tttaacccgg ctctgacgct ggctctggct attgacggaa
    70861 gcttcgactg ggctcttgtt cctggataca tcatcgctca gtttgcaggc gcattcgtag
    70921 gcgctgtcct cgtatacatt ctgttcaaag agcagttcga cgctactccg gatgcaggat
    70981 ccaagcttgg cgtattctgt acaggaccgt ctgttgagaa caaaccatta aacattttgt
    71041 ctgaggcaat tggaaccttc gttctcgtat tcgctattaa gggtcttgca aatgttccag
    71101 gcgcagcaga ggttggcctt gacaaattcc tggtatttgg tatcatcgta tccgttggta
    71161 tgtccttagg cggactgaca ggctacgcaa tcaacccggc ccgtgacctt ggccccagaa
    71221 ttgcacacgc agttctgcct atcaagggca aaggcgattc caactgggga tatgcgcttg
    71281 ttccggtagt aggaccgatc atcggcgcta tcgcagccgt attactctac ggagccattc
    71341 cgtggtaaag cacaaataac gaagttattt gtgcgctact caaacggagc aaagcgtagt
    71401 ttgagtttcc cgtaaggaac gaagttattt gtgcgctgct caaacggagc gaagcgtagt
    71461 ttgagtttcc cgtttagaac gaagttattt gtgcgctgct caaacggagc gaagcgtagt
    71521 ttgagtttcc cgtactgagt gcacagacgc ggaaaacgaa ttataactaa ataagtattg
    71581 catggagaga tgagccgggc aaggagatca tcagcttaca ggctgattcc tctgccgggc
    71641 tctctttaat tttctgataa aaaagtgata aaaatcaaat tgcagaaaca ataacagagc
    71701 tgcagcaagg aggaatggaa tatgtatgac gttattatta tcggcgcagg cgtttccgga
    71761 tgtgcgtcag ccagagagct gtcacggtat gagggaaaat tctgcgtcgt agagaaggaa
    71821 gaggatgtgt gctgcggcac ttccaaggcg aacagcgcca ttgtccacgc aggctatgac
    71881 gcggccacag gttctctgat ggccaaactg aatgtggaag gcaatcagat gatggagcag
    71941 ctgtccaagg atctggattt ccacttcaga agaaacggtt ccctcgtact ctgtatgcat
    72001 gaggaggaac ttccgaatct ccaggctctc tatgagagag gcattgccaa cggcgtgaag
    72061 gagcttcgga ttctcagcag agaggagctc aaggagatgg agccgaatgt tacagaaaac
    72121 gcagtggctg ccctctatgc gcctaccggc ggaattgtat gccccttcgg actgaccatt
    72181 gccctggcgg agaacgccaa catgaatggt gtggagttta agttcaacac agaggtgaag
    72241 gacattcaga agctggagga cggcactttt gagcttcaca cgaacaatgg agtattgaag
    72301 acaaggtttg tggtaaatgc agcaggcgtt tatgcagacg tattccacaa catgatgagc
    72361 gaggagaaga tccacatcac cccaagaaga ggcgattact gcctgttaga ccgcacggcg
    72421 ggagatttag tagacaagac ggtattcacg cttcctggaa agttcggaaa gggtattctg
    72481 gttactccta cgatccatgg aaatctgctg ttaggaccga cagccattga cattgacgat
    72541 aaggaaggca ccaataccac gagagagggg ctggacgagg tcatcgagaa ggctcagcac
    72601 agcgtgaaca acattccgat gcgtcaggta attacctcct tcgcaggtct gagagcccat
    72661 gaggatcacc acgagtttat cataaaggag cttccggact gtaagggatt tatcgactgc
    72721 gccggcatcg agtccccagg cctctccagc agcccggcca ttggcaagat ggtggccgat
    72781 attctgaagg agaaggcaga gcttcatgag aaggacaatt tcattgccac gagaaagggc
    72841 atcctggatc cgaaatccct gtccaaggag gagagatcca ggctgattaa agaaaatccg
    72901 gcttatggaa acattatctg ccgctgcgag actatctcag agggagagat tttagacgcc
    72961 atccacagac ctctgggagc taaatctctg gacggtgtaa aacgccgcac aagagctgga
    73021 atgggacgct gccaggcagg cttctgttca ccgagaacca tggatattct ggcaagagag
    73081 ctgaatatca gcatgtatga ggttaccaag tccggcaaag attccaaaat tgtagttgga
    73141 acaaacaagg acaaactgta aggaggggga cgccatgaaa tcatatgata ttgtcgttat
    73201 cggaggaggc cctgcaggac tggctgcggc agcggctgca aagagaagcg ggatcgacag
    73261 catcctgatt ctggagcggg ataaggagct gggaggcatt ttaaaccagt gcattcacaa
    73321 cggattcggc cttcacacct ttaaggagga gctgacagga ccggagtatg cacaccgctt
    73381 cattgagcag gtgcaggagc tcaacataga atattgttta aacaccatgg tcattgatat
    73441 ttcccacgag aaggtagtta cggccatgaa ccgtgaagag gggctgttcg aaattcaggc
    73501 caaggccgtg atcctggcta tgggctgcag agagcgttcc agaggagctt taaatattcc
    73561 gggctatcgt cccgcaggca tttactcagc cggaacggct cagcgtctcg tcaatatgga
    73621 aggctttatg ccgggccgcg aggttgtcat tctgggatct ggcgatatcg gcctgatcat
    73681 ggccagacgt atgaccctag agggcgccaa ggtgaaggta gtggcagagc tgatgcctta
    73741 ttctggcgga ttaaagagaa atattgtaca gtgtctggac gacttcggca ttccgttaaa
    73801 gctgagccac acggttgtgg agatccgcgg caaggagaga ctgaccggca ttacgctggc
    73861 gcaggtagac ggcagaggaa agccgattcc tggcacagag gaggactatg actgcgatac
    73921 gctccttctg tctgtaggct taattccaga gaacgagtta agccgcggca tgggtgtgga
    73981 cattgagccg attacctccg gaccgtctgt caacgagagc ctggagacga atatcgacgg
    74041 cgtatttgcc tgcggaaacg tgctccatgt tcacgatctg gtagattatg tatctgagga
    74101 agcagctgca gcaggagaga atgcagccaa atatgtgaag ggcatcctgc cggcaaacag
    74161 cggaaaagag attaaactgg ttcctacaga cggagtccgc tataccgttc cgaagacaat
    74221 tgatccggag agaatgacag acgagctgac tgtccgcttc cgcgtgggca atgtctataa
    74281 aaactgcttc gtgagcgttt acttcgacgg cgagcgggta gtccacagaa aacgtcccgt
    74341 actggctccg ggcgagatgg agaacgtgaa gttcaagaag acgcagcttg cgtcctatcc
    74401 tgatttaaag acgattacac tgaaaataga ggaggcgtaa ggctatggaa aaaagagaac
    74461 tgatctgcat cggctgccct ctgggatgta tggtgaccgt tgagatggaa aacggcgagg
    74521 taaagagcgt gacaggcaat acctgtaagc gcggcgacga ctacgcccgc aaggaagtga
    74581 cgaatcctac cagaatcgtt acctccacgg tcatggtaaa gggaggaagc cttgacatgg
    74641 tttccgtaaa gacgaaaaac gatattccca agggaaaaat cttcgactgt gtccgcgccc
    74701 tgaagggcgt ctgtgtggaa gcgccggtac acatcggaga cgtggttgtt tccgacatct
    74761 gcggcacagg agtagatgtg attgccacaa aggaaattga ggaaaagaga gcatagaagc
    74821 cagcctgcat aaggcagact atttcagggg agaggcagag tacagaaaaa gagctgtgtt
    74881 ctgcctctct ttgcgtctgg tttgacggtc atggcacacc ttgacgcaga cgtatggctt
    74941 cctgcggcag aagagaaggc ctgccagtag caaaaacagg gagaatggga tataataatg
    75001 gaaagcagcc ggcaatgcgg ctgcggaata cagaaaacag agaggataac aggatggttg
    75061 agatttgctg cggaagctat gaggacgctg tgtccgccag ccgcggaggc gctgagagga
    75121 ttgagctgaa ttctgccctg gctttaggcg ggctgactcc tccggcggga tgcgtcaggc
    75181 tggtaaaaga gcgtacggat ttaaaggtga tttccatggt aagaccaaga ggaggaggct
    75241 tttgctatac agctctggag acagagcaga tgtttgagga cgccaaaatg ctgttagagt
    75301 atggaagcga cggcctggcc tttggattcc tgacagagcg gggagaaatt gatctggaaa
    75361 aggctggcag aatggtcaga ctcatccaca gctatgggcg cgaggcagtg ttccaccggg
    75421 cttttgactg taccagagag ccggaggagg ccgtttccag tctgattgct gtgggggtgg
    75481 atcggatcct gaccagcggc ctgaaggaga cagcctggga agggcgggaa ttgttaaaaa
    75541 agcttcagca tgaattcgga ggacagatcg agatcttagc tggaagcggc gtgaacgcag
    75601 aaaacgccgg agcgctgatg gaatggacgg gaatttctca gattcattcc tcctgccgcg
    75661 ggtggaaaaa cgatcccact acttccggag agaatgtgag ctacagcttt gctgctgcgc
    75721 cccatgagaa tgactatgat gcggtggacg aaagcctggt gaaacgtctg gtggagaggg
    75781 ctgggaaatc tgtgtagcgg gagatttcct ggcggaagct gttctgcctg agtctgtaca
    75841 gaaggaggag acgccatgac gggaaaaaaa ggcgtgattt taaaacgttt aacagtgggg
    75901 aaaattctgc tgatttttct tattatttac attggatttt tagttttgcc ttatgtctgc
    75961 cataagaagg ttccggcttc ttatcaggag agcttcgacg tatcctcctt ttacggcagc
    76021 ggaccgggac cggagcggac ggcttacata gataataatg atgatgcgct tctctggaga
    76081 ctgcgcctga ttgaggaagc cagggaggaa attatcctgt cgacgtttga ctttaaatcc
    76141 gatgaggcgg ggaaggatat tatcgccgcc ttgatgcagg cgtcggatcg gggcgtgcag
    76201 gtacgggtga ttgtggacgg atttaatgga gtgctgaagc tgacaggaaa taaatacttt
    76261 aaagcgctgg tatcctgccc cggcgtttcc attaagattt ataatcctat cagcccgttc
    76321 aggccctggg atatgcaggc cagactccat gataagtatc tgatcattga taacagcatg
    76381 tatatgctgg gtgggcgcaa taccatggag ctgtttctgg gagattattc gcctgagaaa
    76441 aatgtggatc gggagctgtt tgtgtacgag acgaaacagc cggatgaaaa cgcctccatt
    76501 tctcagctca ggaggtattt tgagaccgtc tgggcgcttc acgacagcag agaatacgtc
    76561 tgccggaaaa agacctcctc tgtggagcag gcggataagg aattgcggga gcggtacgag
    76621 tacctgagag agacttacag cgaggcctac acagactggg atttcactgc gctgaccatg
    76681 gaaacgaacc ggatttcact gctttccaat ccgattgaga cagaaaataa agagccgctt
    76741 ctgtggtatt ctcttcagca gctgatgcag gaggcggatc aggtgaccat gtacacgcct
    76801 tacattatct gtgggaagga gatgtatcag ggactggagg agctgaaaaa cagaggcgtt
    76861 tctgtggaaa tgatcacaaa cgacgtggcc agcggagcca atccgtgggg ctgtacagat
    76921 tatttgaatc agaaggagaa gatctgggac acaggagtga aggtgtacga gctgatggga
    76981 gaatattcca gccatacgaa ggcagtgctg ctggacagcc ggatgagtct ggtgggctcc
    77041 tataatttcg atatgcgcag cacctaccag gatacggagc tgatgctggc ggtggactgt
    77101 cctgaactga accgtatcat ccgccaggag gcagagcggg ataaagcgaa gagcaaaatc
    77161 atgggggcaa acggggaata tcagtacgga gaaggctacg ttcccaggga gatgagccct
    77221 ggaaagaaga tattttacgc cattatgaga gttctggtaa ttccgctgcg ccgttttctg
    77281 taaagagcgc tataatagaa atatggcgaa agctattttc attccccaca tcacacttcc
    77341 tgcattagtg tgcgtcgcca gacagagcaa tgtgtttgac tggcatggca gcgcgtgggt
    77401 gggagagaac attccaggcg ccagaaccgt attttttgaa cattccggac atatgctgtt
    77461 ctgggatgag gcagagaaat ttaaccggga agctgcagac tttgtatgca ggcactgatg
    77521 cctgaagaaa aaggctgtca gacatagaag ggacatagaa agtaacatag aaagggcgct
    77581 gcgctgtcat cgtgtttttt acttctgaag tgggtatctc gtatgcctcg caggtatgct
    77641 caaatatatc cgcatcccaa atttgattac cgaactcgtc gcaattttcg gggtcataca
    77701 aacatcccca ccacaatgcc atatacgcat acggattatc tattttccat tcattttctc
    77761 ctacgataaa tcgcggccat ccacgtcgga tgcgctcttc ctcagctcgt tgttttagcg
    77821 cttcgccttc ttttcttcga tctggtttga tctcgttatt aaaaaatggt gtcatggcat
    77881 tttttaaagg attgtatttt ttatagttta aatcccagtc gtctgggtgc attttgcgcc
    77941 accattgata tttttgtgca gcttccggaa gtccataatg atagccaagc tccgttctcc
    78001 aaagtaagtc aagttcttca tattcttcat gactaatcct aaccggtacg gcattttcgt
    78061 cgatattatt cggaaaatag ctttttgttc ccataatctg gccacgttta tttaaaaagt
    78121 catcat
//
LOCUS       DBMDUW010000004        77277 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_386_length_77277_cov_3.863585, whole genome shotgun sequence.
ACCESSION   DBMDUW010000004 DBMDUW010000000
VERSION     DBMDUW010000004.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 77277)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 77277)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77277
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_386_length_77277_cov_3.863585"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(119..1387)
                     /locus_tag="ACZPCR_01570"
     CDS             complement(119..1387)
                     /locus_tag="ACZPCR_01570"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013271394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HIR1229612.1"
                     /translation="MEKKPFVTLEQLKEITKTYKTPFHLYDEKGIRENAERLKRAFSW
                     NKGFREYFAVKATPNPFIIDILKKLDCGVDCSSMTELMMAEAMGYDGKKIMFSSNDTP
                     AEEFQMADRLGAVINLDDITHIEFLEKAVGHIPETISCRYNPGGLFKISNDIMDNPGD
                     AKYGMTTEQMFEAFRILKEKGAKRFGIHAFLASNTVTNEYYPMLAKVLFELAVRLKEE
                     TGAEIAFINLSGGIGIPYRPDQEPNDIFVIGEGVRKVYEEILVPAGMGDVALYTELGR
                     FMLGPYGCLVTTAIHEKHTHKEYIGVDACAVNLMRPAMYGAYHHITVMGKEDAPCDHK
                     YDIAGSLCENNDKFAIDRMLPKIDMGDLLVIHDTGAHGFSMGYNYNGKLRSAELLLKE
                     DKSVQMIRRAETPKDYFATFDFCDLFQNVK"
     gene            complement(1422..2858)
                     /gene="pyk"
                     /locus_tag="ACZPCR_01575"
     CDS             complement(1422..2858)
                     /gene="pyk"
                     /locus_tag="ACZPCR_01575"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002593239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HIR1229613.1"
                     /translation="MKKTKIICTMGPNTNDRELMKQLALNGMDVARFNFSHGDYEEHM
                     GRFKILESVREELGLPIAALLDTKGPEIRTGSLKDGKKVTLKEGDVYTLTTEETVGDH
                     TRGFINYAGLPADVKPGNQILIDDGLIELDVEEVKGNDIVCRVKNGGELGEKKGVNVP
                     NVKINLPALTDKDKEDILFGIQAGFDYIAASFVRNAGAIREIKEILEKHGSRMLVIAK
                     IENAEGIENLDSILEECDGIMVARGDMGVEIPAEKVPHIQKLIIKKCNKACKPVITAT
                     QMLDSMIRNPRPTRAEVTDVANAVYDGTDAVMLSGETAMGRYPVEAVRMMAQIVEDSE
                     KYLDYASYRQRRVSQENQKNISNAVCYSSVATAHDLGAAAIVAPSVSGFTARMLSKWR
                     PSATIVGLSPSMTTVRQMQLYWGVKPFHAKRADSTDVLVYSSIELLKEKGIVKTGDVV
                     VATAGVVTYANRHSPAANTNIMRVAEVD"
     gene            complement(2951..3787)
                     /locus_tag="ACZPCR_01580"
     CDS             complement(2951..3787)
                     /locus_tag="ACZPCR_01580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229614.1"
                     /translation="MKFLRKLERNFGKYAVPNLMYYIILMYGAGIVIDLVMPGLYYQY
                     LCLDAAAILRGQVWRLVTFLICPPSSGIFFNLIAMFLYYSLGTTLERVWGTFRFNLYF
                     FSGILFHIIAAFVIYFLMGVSVPLTPFYLNNSLFLAFAATFPQMQFYLYGLLPIRAYW
                     LGIFIGAEFLYEFLFGGLIARSCIGLALLNFVIFFMMTRNYSKISPREIKRKQKFKSD
                     MKTAQAEKIRLTHHKCAVCGRTEKDDPNLEFRYCSKCEGNLEYCMDHLYTHKHVTKED
                     LE"
     gene            4031..8302
                     /locus_tag="ACZPCR_01585"
     CDS             4031..8302
                     /locus_tag="ACZPCR_01585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008752601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydratase activase-related protein"
                     /protein_id="HIR1229615.1"
                     /translation="MKSCKRLGIDIGSTTVKVAIIDDSGSILFADYERHFANIQETLA
                     LLLKRAVEALGEMELYPVITGSGGLTLSSRLEVPFVQEVVAVASSLQDYAPQTDVAIE
                     LGGEDAKIIYFTGGIDQRMNGICAGGTGSFIDQMASLLQTDASGLNEYAKNYKAIYPI
                     AARCGVFAKSDIQPLINEGATREDLAASIFQAVVNQTISGLACGKPIRGNVAFLGGPL
                     HFLSELRAAFIRTLNLGPDQIIAPDHSHLFAAVGAAMNSRQEVKMDAQALIRRLSEGI
                     QIDAEVKRMEPLFENQEAYEKFQARHASHCVKKGSLKDYKGNCFLGIDAGSTTTKVAL
                     VGEDGTLLYHFYSNNNGSPLATAIRAMSEIQSELPEEAHIVYSCSTGYGEALLKAAFM
                     LDEGEVETISHYYAAAFFEPDVDCILDIGGQDMKCIRIKDGTVDSVQLNEACSSGCGS
                     FIETFAKSLNYSVIDFAREALFAKTPTDLGTRCTVFMNSNVKQAQKEGASVADISAGL
                     AYSVIKNALFKVIKITNASDLGEHVVVQGGTFYNDAVLRSFEKISGCEAVRPDIAGIM
                     GAFGAALIARERYDASKETTMLPMEKILNLSYKTSMTRCQGCTNHCVLTINRFDGGRQ
                     FVTGNRCERGLGHAKKKADIPNLFDYKYHRMFDYEPLTADVAERGTVGIPRVLNLYEN
                     YPFWAVFFKELGFRTILSPQSTRKLYELGIESIPSESECYPAKLAHGHVEWLIKQGVT
                     YIFYPCIPYERNETPEAGNHYNCPMVTSYAENIKNNVEELHGDKILFRNPFMAFTNKE
                     VLSEALVKEFTEQFQIPEQEILDAADKAWAELIASREDMKRKGEETLQWLKKNNRRGI
                     VLAGRPYHVDPEINHGIPELIASYGFAVLTEDSVSHLGHVERPLIVTDQWMYHSRLYA
                     AANFVKTQKNLDLIQLNSFGCGLDAVTTDQVNDILTRSGKIYTCLKIDEVNNLGAARI
                     RIRSLISAIRVREMKHYDKPAVSSAYNRVLFTKEMKKDYTILCPQMSPIHFDLVEAAI
                     RSCGYRLEVLQNSDRTAVDTGLKYVNNDACYPSLIVVGQIMDALLSGKYDLNRTAVIM
                     SQTGGGCRASNYIGFIRRALEKAGMPQIPVISLNANGMETNPGFSFTLPMVIKALQAV
                     VYGDIFMRVLYATRPYEAKPGSANALHQKWKETCIQSLSRKKPSMKEFGNNLRAIISE
                     FDALPRKNVVKPKVGIVGEILVKFSPLANNHVVDLLESEGAEAVMPDLLDFLLYCFYN
                     SNFKAENLGGKKSTAWLCNAAIQLLEYFRRTARKELEKSVHFTPPARIHDLAAMAKSY
                     VSLGNQTGEGWFLTGEMLELIHSGTNNIICTQPFGCLPNHIVGKGVIKELRASHPEAN
                     IIAVDYDPGASEVNQLNRIKLMLATAQKNLERECAEEAAVSREMA"
     gene            8411..8875
                     /locus_tag="ACZPCR_01590"
     CDS             8411..8875
                     /locus_tag="ACZPCR_01590"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229616.1"
                     /translation="MGLKTFACALALTLSYTVTAFGAEPQTALQTLSSDVVKAASNEA
                     IPMTGSKIVTDDFSFVVPERWTGKCVVLPTEQGLEVYDQEDYESDGSGFLFSISVYED
                     DSYSSLEDYAILGFCGSETFVLDTSKADESKSVKKGLKELQETFVAFAGNEN"
     gene            complement(8965..10218)
                     /locus_tag="ACZPCR_01595"
     CDS             complement(8965..10218)
                     /locus_tag="ACZPCR_01595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1229617.1"
                     /translation="MKKKQKIRNKWLTGSLLFLTLSASFPAQAARSPEVTETELLRSG
                     EGDEAELEGPGLGENGEEKETEDGETDSFTEEELTDSLIEYGELEELLKRGNASLKSA
                     VSQYDTNLEIYQEALEVLSSAKQEMKEYAEELENENGSPELIAQYQMNESQLGASVAQ
                     MNRTVRKLTGVSGTKFLKSSVNAMVKTAQTVMCSYNQMRDQRQLAEKQEESARASYEK
                     AQTMAEAGMLTEQELLEAEQSLLTARISLQSAEKSEASMKAQLSLLIGRNPDDTEIGE
                     IPPANVDFIDTVVLEDDKKLAVISDSEIQALRRGSSSGGSAEAELKSRQISEAKSRKN
                     LEMDTLYNEMTAKLQAFQAAESSYEAAEKNYGALQVKYQSGLLSRQEYLKGEVSYLQQ
                     KNSFKQAERELSQTIAAYQWEIKGV"
     gene            complement(10250..11419)
                     /locus_tag="ACZPCR_01600"
     CDS             complement(10250..11419)
                     /locus_tag="ACZPCR_01600"
                     /inference="COORDINATES: protein motif:HMM:NF014385.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1229618.1"
                     /translation="MKKWWVQKTALAAGMTAVFQLCFPLQAWAASPPFAYTEEEWAAI
                     RDNKLEFEEIDKRIHEYNTTVRQNEISYKDYQGKDSSEIAQEYYDAAEEIYDSQPDLD
                     PDSSSYASALASYINNEQRAESLKESGDASVEDEDTVKWSYIQAEKKLVRQAQSLMIS
                     YWSSVEKLSSLEQELLEAENSEESVKRKLAAGMAVQSEVLTAEQTVLNLKSEITSEQS
                     SLKETKTSLILMLGWNEGDSVEIGSLPEPDPAAIAGISLETDIEQALENNYDLKILGR
                     QLQNAHSSTTEASVRETLTSGRQAVRANVTMAYQNLLLAENQYEQAVKAKYLKEQSLE
                     TARRKQEAGLLSANSLASAVSACETAESSKQTASFQLLSAKLEYDWAVAGLAAVS"
     gene            complement(11442..14459)
                     /locus_tag="ACZPCR_01605"
     CDS             complement(11442..14459)
                     /locus_tag="ACZPCR_01605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008398982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0042908 - xenobiotic transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HIR1229619.1"
                     /translation="MGITKFVLKRPVTVIMTLLCLLVFGISSVFHASLEQMPEMETPM
                     MTIMARYEGAGPEDISELVTEPIEDAVSTLEGVKSISSSSSDGSARIMLEYDYGTDMD
                     EAYNELTKKMSSLERQLPEDMDTPTVMEMGQNAGTSMMLSISHKTETDLYSYAEQKIV
                     PELEKIASVASVEAMGGTSEYIQVELNREKMDQYKVTMSQISSAIQNANVSLPSGDTV
                     SGNLELSVTTSLETSDIEELKNVPVTASTGEIVRLQDVADVHTKEEKRGGISRYDGAE
                     TISISVMKNQSNTDIEVSRAVRETIQELQDADPDLTAEVVNDTADTILESLKDVAETM
                     VLSVIISMIIIFLFFGDLKASLIVGSSIPTSILLSLIAITAAGSSLNVITMSALVLGV
                     GMMVDNSIVVLESCFRAAELNRDKGIFGYAKAALLGSNQVLASIIGGTATTCVVFLPL
                     AAVQGMSGQMFGPLGYTVVFCMVASLLSAITVVPLCYVMYKPQEKSSSFMSGPVERLQ
                     NFYRKVMKKLLRHKGRVMAVSAAMLAATFCLASGMRSELITSDDTGQIKIEIETRPGL
                     IEEKTEDALARIEEIVSSNENVDSYMLRYQNQSGSVTAYLKDDRTEDTAQLAEQWQQE
                     LSDIENVSTEVTAGSSMSFMQRTRGYETILTGTDYGELKELSDKIVSELISRDDVINI
                     HSSFENNAPIVSIDVDPLMASRKGLTASSIGSAVNQTLSGMTAAALTVDGEDLDVKVE
                     FPEGEYASIDQMKNIILTAGDGTATALTDVADIVYKDSPSSISREDQSFKVTITGEYT
                     GADTSAQIESEVIAPNLTGTIKKGTSSMDRMMNEEFSSLYQAIAVAVFLIFVVMAAQF
                     ESVKFSVMVMTTIPFSLIGSFGFLKLTGVSMSMTSILGFLILVGTVVNNGILYVDTVN
                     QYRMEMDLETAMIEAGAVRLRPMLMTSLTTILGMLPMAAAMGSSGSTTQGLAIVDIGG
                     LTAGLFVALFMLPVYYGLMNRKPRKINEDWDID"
     gene            complement(14475..15671)
                     /locus_tag="ACZPCR_01610"
     CDS             complement(14475..15671)
                     /locus_tag="ACZPCR_01610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007708572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1229620.1"
                     /translation="MDKKNLNREWLLRTSDRLMKKKKIVIPAALIFIAAAAFASGRGG
                     KRPEGRPADMDRQMNVTAVSAEPPGTGSIELETAVTGTVEPSDVVYLYARAAGDVTSV
                     LVKAGDTVEAGQLLAVIDTKQVEAAENAMESARLSYESAQSTLSRQELLYAGGDISDQ
                     EYEQYQNQAESARLSYESAKMSYENQMEYSNITAPVSGVIESCSIEAFDHVSANEELC
                     VISGEGAQTLKFKVTERVARHLSAGGELRVERDGETYSGSITEVSGMADASTGLFEVK
                     GSINGADSVALGSVVKIYLVSDRAENVMTVPVDAVYFDGGVGNVYLYQDGKVHKQEVE
                     VGIFDSNLAEIQSGLTESDLVISTWSSELYEGSTVKLKNEKTGEQPDRQQKENAGEPL
                     DPMPEP"
     gene            15871..16548
                     /locus_tag="ACZPCR_01615"
     CDS             15871..16548
                     /locus_tag="ACZPCR_01615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIR1229621.1"
                     /translation="MFNILVVEDDRKLRNLFCTVLSHSGYCAIPAENGMSALGILDTE
                     YIDLVISDIMMPGMDGYELIETLREHGYTMPILIITAKAQFEDKQRGFWAGTDDYMVK
                     PIDVNEMVLRVGALLKRARISTERKIVCGNTVLDYDALTVRCGREVSLLPQKEFYLLY
                     KLMAYPNKIFTRRQLMDEIWGMDSSSEERTVDVHINRLRERFKDCTDFQIQTVRGLGY
                     KVVKQES"
     gene            16545..17567
                     /locus_tag="ACZPCR_01620"
     CDS             16545..17567
                     /locus_tag="ACZPCR_01620"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HIR1229622.1"
                     /translation="MKRHISPIKFYIILIILACTTVTPTLAGWLLFHFSDWKYGPNPY
                     FPLMNTLIESLLAGIFLTLMINHFLLSPIMSFIDAINQVSKGDFSVRVKTDYSSPELD
                     ELAGHFNKMVQELGSIEALRNDFAANISHEFRTPLAAIEGYTTLLQDHSLSDQERDEY
                     THIIIDSVRQLSSLSENILSMSRLEKQEIVTNKTTYSLDEQIRQAVLLLEPLWSEKKM
                     ELDIDLESALYYGNCDMMMQVWLNLLHNAIQYTPAEGTISVFLKKTKHSLLITVADTG
                     IGMDEATLSHIFDKFFRKDKDSSPGNGLGLPMVKRILQLNQGSVTVESTPGSGSSFVV
                     TLPVQK"
     gene            complement(17648..18514)
                     /locus_tag="ACZPCR_01625"
     CDS             complement(17648..18514)
                     /locus_tag="ACZPCR_01625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015520615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009037 - tyrosine-based site-specific
                     recombinase activity [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA];
                     GO_process: GO:0007049 - cell cycle [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase"
                     /protein_id="HIR1229623.1"
                     /translation="MFDEIERFAVYLQDVKRMSQNTILSYRRDLLQFASYMEDRGVRE
                     AGKVTKTSLDSYILFLEKERKAPATISRMLASIKAFFHYEFSEGRIRRNPADLVRAPK
                     IEKKAPAILTVEEVTRLLAQPSGRTPKEIRDKAMLELLYATGIRVSELMNLSLSHVNM
                     TIGFITCSDSGRERTIPFGRVAKKALDDYMKHSRPELLKQKESEWLFVNCSGGRMSRQ
                     GFWKILKYYGEKAGIQADITPHTLRHSFAAHLISSGADIKAVQQILGHSDMATTQMYV
                     SYAGSGKTGSGK"
     gene            complement(18525..18854)
                     /locus_tag="ACZPCR_01630"
     CDS             complement(18525..18854)
                     /locus_tag="ACZPCR_01630"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229624.1"
                     /translation="MGPERRKKGPGGGIPDSFGSSGGRIRRRGMAESQMDIMDRSNLF
                     LLKKAEKNSISCVDKDDKTISCVFFVNPMKGCGKVGKMCLIYGENVDIMVVTSGFCLV
                     FTAIQND"
     gene            complement(18887..19279)
                     /locus_tag="ACZPCR_01635"
                     /pseudo
     CDS             complement(18887..19279)
                     /locus_tag="ACZPCR_01635"
                     /inference="COORDINATES: protein motif:HMM:NF014052.6"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
     gene            complement(19343..19936)
                     /locus_tag="ACZPCR_01640"
     CDS             complement(19343..19936)
                     /locus_tag="ACZPCR_01640"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007157618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016817 - hydrolase activity, acting on
                     acid anhydrides [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HIR1229625.1"
                     /translation="MEKNKRTAEEAEAAKNLADIPVKRVNRELKYQGAILKVYQDTVQ
                     VNGHEAKWDYIHHNGAAAVVAVTKEGKLLMVRQYRNALDRYTLEIPAGALDYPEEPKI
                     ECAYRELEEETGFKTEHLEYLLSINTTIAFCDEAIDVFVARNLIPSKQHLDPDENIQV
                     EEWELEDLLKLIYSGTITDGKTAASILAYAVKYGCQK"
     gene            complement(19976..20833)
                     /gene="proC"
                     /locus_tag="ACZPCR_01645"
     CDS             complement(19976..20833)
                     /gene="proC"
                     /locus_tag="ACZPCR_01645"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002593241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0055129 - L-proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HIR1229626.1"
                     /translation="MKPAFKGNKEEKKTDGGERRMKKIGFIGMGNMGYAILKGLLQVF
                     DKTELILTDANQERAEAVSRETGVEAAGDNQSCASQAEFVVLAVKPQFYHMVLDDVKD
                     IIKKEQIIISIAPSVTIADLKAALGQDKRIVRAMPNTPALVGMGVTGVCYDRKEFTQE
                     EEAVIRTFFESFGTMELVEERLINAVVCASGSSPAYVYMFIEALADSAVKYGLPRDTA
                     YRMAAQAVMGSAKMVLETGEHPGTLKDRVCSPGGTTIAAVSALEEHGFRSAVIKAADA
                     CYEKCLNMK"
     gene            complement(20982..22511)
                     /gene="rny"
                     /locus_tag="ACZPCR_01650"
     CDS             complement(20982..22511)
                     /gene="rny"
                     /locus_tag="ACZPCR_01650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008372294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HIR1229627.1"
                     /translation="MCVVTAVIVAVITWFVAVNHQKKTYEAKIGSAEERSREIIDEAL
                     KVAETKKREALLEAKEESLKTKNELEKETKERRAELQRYERRVLSKEENLDKKSEAIE
                     KREAGLNTREDALKKRTTEVEELYEKGMQELEKISGLTSEQAKEYLLKSVEEDVKHDT
                     AKLIKEMEAKAKEEADKKAKDYVVTAIQRCAADHVAETTVSVVQLPNDEMKGRIIGRE
                     GRNIRTLETLTGVELIIDDTPEAVVLSGFDPIRREVARIALERLIVDGRIHPARIEEM
                     VEKAQKEVETMMREEGEAALLEVGIHGIHPELVKLLGKMKFRTSYGQNALKHSIEVAQ
                     LAGLLAAEVGVDVRTAKRAGLLHDIGKAVDHEMEGTHVKLGVDLCRKYKESAIVINAV
                     ESHHGDVEPQSLIACLVQAADTISAARPGARRETLETYTNRLRQLEDITNSFKGVDKS
                     FAIQAGREVRIMVVPEQVNDDGMVLMAREISKRIEAELEYPGQIKVNVIRESRVTDYA
                     K"
     gene            complement(22642..23247)
                     /locus_tag="ACZPCR_01655"
     CDS             complement(22642..23247)
                     /locus_tag="ACZPCR_01655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006782979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein RecX"
                     /protein_id="HIR1229628.1"
                     /translation="MIIDRIETLDRRRKKIFADGEFAFALYLGEIRQLGLEEGGELAE
                     ELYQKILREIIFKRARERAVYWLKCSARTEEELRRKLRDNSYPPAAVDYVIDLLKQYR
                     YIDDEEYARNFIEVHASGKSRAELAALLSRKGISRECVSRLMEENPVDEEAQIRRILE
                     KRRFHPEEADQKETARQTAYLMRKGFSYDTVRRVLSETFVR"
     gene            complement(23250..24323)
                     /gene="recA"
                     /locus_tag="ACZPCR_01660"
     CDS             complement(23250..24323)
                     /gene="recA"
                     /locus_tag="ACZPCR_01660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HIR1229629.1"
                     /translation="MDREEKLKALDAALTQIEKAYGKGSVMKLGDSSANMNIETVPTG
                     SLSLDIALGLGGVPRGRIIEVYGPESSGKTTVALHMVAEVQKRGGIAGFIDAEHALDP
                     VYAKNIGVDIDNLYISQPDNGEQALEITETMVRSGAVDIVIVDSVAALVPKAEIDGEM
                     GDSHVGLQARLMSQALRKLTAIISKSNCIVIFINQLREKVGVMFGNPETTTGGRALKF
                     YSSVRMDVRRIETLKQGGEMVGNRVRIKVVKNKIAPPFKEAEFDIMFGKGISKEGDIL
                     DLAVKENIVEKSGAWYAYNGSKIGQGRENAKGFLQANQEMCQEIEAKVRAKYSLDGAS
                     EEEKGAEKADAAKLAMPEFDSEE"
     gene            24772..26118
                     /locus_tag="ACZPCR_01665"
     CDS             24772..26118
                     /locus_tag="ACZPCR_01665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004850675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HIR1229630.1"
                     /translation="MLSNRVWALTPAKIILGGFFLIITAGALLLTLPISSKSGEMTPF
                     IDAFFTATSATCVTGLVVHDTYTYWSVFGQSVILLLIQIGGMGVVTLAIAITILSGRK
                     IGLKQRFVMQESISAPQVGGIVRMTNFIIKGTLLLELIGAFIMAVQFCPQFGVIKGIW
                     FSIFHSISAFCNAGFDLMGGTSGLYSSLTSYHSNPLIVVPVMLLIVVGGIGFFVWDDI
                     IQHRETRRAFRLQTKVVLTYTFFLILIPAVLFFLFEFTPQRWEGYSLADRLYASFFQS
                     VTPRTAGFNTVPLDGLSTQAQLLTIMLMIIGGSPGSTAGGIKTTTFAVALLCIRSVFQ
                     NQEGIHCYKRRIPYEILRNAIAILVLYLSLFLAASFLITWADGVTLMESSFEAASAIA
                     TVGLSLGITEDLSLFSKMILILLMYFGRVGGLTMLYALTNHKKFPFHLPEEKITVG"
     gene            26146..26799
                     /locus_tag="ACZPCR_01670"
     CDS             26146..26799
                     /locus_tag="ACZPCR_01670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HIR1229631.1"
                     /translation="MKSILLIGLGRFGATMAMKLHELKHEVMAIDISEERINAILPYV
                     TSAQIGDCTNEQYMSSIGVRNFDLCIVAIGDNFQSSLETTALLKDLGAKFVLSRANRD
                     IHAKFLLRNGADQVVYPEKEMAIRSAVRYSTDNIFDYIELTPDHSIYEVPVPSSWIEK
                     SIVQINVRNKYHISILAVKLGKELRTLPGADYVFMGNETLVILGANTDIKKFLSTAK"
     gene            complement(26908..27726)
                     /locus_tag="ACZPCR_01675"
     CDS             complement(26908..27726)
                     /locus_tag="ACZPCR_01675"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HIR1229632.1"
                     /translation="MRFTVLNENTAGKRGFLAEHGLSVLIVHQGRKLLFDTGQTDVFL
                     HNAEKIGETLSDLDGIILSHGHFDHCGGLEYLAKQRKLPPVYVRKTAFLNKQAINDDK
                     KTYRIIGIPWKQELLRETEVLTEDKQEIFPGVWVLGNVPYTVPFEKKPGIFFIDRGGE
                     KQPDDMEDEQLLVIETEKGLCVFAGCCHAGIINCLSYVKKSFPGRPVYSVLAGMHLSA
                     AGDERIDQTIEALKGMDISVLMPVHCTGIYGIGKMKAVFGDTCRLLETGAAVEL"
     gene            complement(27741..28631)
                     /locus_tag="ACZPCR_01680"
     CDS             complement(27741..28631)
                     /locus_tag="ACZPCR_01680"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HIR1229633.1"
                     /translation="MDQAKNWIHCDGAYRLGLTGKGVGVAVLDTGIFPHRDFEDRVVC
                     FADFVKGRREPYDDNGHGTHIAGIIGGAGLESGGRYHGVAPGCSLISLKVLDHRGNGY
                     ASDVLAGLKWIREHKEEFGIRIVNISVGSFNKKGMDENSALVRGVDAAWDAGLVVVVA
                     AGNNGPGRYTITTPGISRKVITVGCSDDHKEVDVAGSRMVDYSGRGPTSACVLKPDII
                     APGSHIISCANRSGCYTGKSGTSMSTPLVSGAIALLLEKYPDMTNLEVKLRLRERVVD
                     LGLPRNQQGWGLLDVGRFVE"
     gene            28886..29341
                     /locus_tag="ACZPCR_01685"
     CDS             28886..29341
                     /locus_tag="ACZPCR_01685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004075006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="HIR1229634.1"
                     /translation="MTFPSFLPAAGIVLAGCLLVILIICRKKRLPYEAKPLLTKREYA
                     FYRLLKREADARGFLICPKVGLKDLMEVTDKTNFLQYFRKISQKHVDFVICDKNLRVL
                     FAVELDDSSHDTADARKRDLFKDQAFRAAKIPLKRIRYFNEASVKELFR"
     gene            complement(29393..30403)
                     /locus_tag="ACZPCR_01690"
     CDS             complement(29393..30403)
                     /locus_tag="ACZPCR_01690"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003509003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HIR1229635.1"
                     /translation="MTVRRIAEKIRKKAARGLALGLCLGLLSAGRLTSYADGPSGPAS
                     DGAAVAAESAKEAQAEGPAQNMETESVGQAETGGQPEGAFQENQQAQAEGQNGAENQA
                     AGSKDQSAGAEGQAADGKTEDGRIMSGGRLIDPSKPMIALTYDDGPYAPVGNRIMDCM
                     EKYNGRATFFVVGNRAGSYQEELRRMQASGHEIGNHSYSHKYLQKLGAADIRKEIEMG
                     NQAVAAVTGTAPALVRLPGGGSNATVLANIHQPIILWNVDTRDWATKNADQTVAAVLG
                     KVKDGDIVLMHELYKPTADATERMVPALAEQGFQLVTVSELIRFRGGAAPGTLYYKFP
                     PQ"
     gene            30636..31433
                     /locus_tag="ACZPCR_01695"
     CDS             30636..31433
                     /locus_tag="ACZPCR_01695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006860865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HIR1229636.1"
                     /translation="MSRPTKCRRVCHFPPSPGFFPIQKGEADTPVILTVDEYETIRLM
                     DLEGLSQQECSQWMEVARTTVQRIYENARKKLALALVEGRPLRIGGGDYRLCDGQESC
                     GHDECFKRTYHQQYEKKKGADTMRIAVAYENGQIFQHFGHTEQFKIYDAEGGAVRQSE
                     IVDTNGRGHGALAGILHALNADVLICGGIGQGAKDALEAAGIKLYGGVSGSADEAVSS
                     FLNGTLSFQPDVICSHHSERHGEGHTCGEHGCGEHEHGTHGCGGHCQ"
     gene            31601..33007
                     /locus_tag="ACZPCR_01700"
     CDS             31601..33007
                     /locus_tag="ACZPCR_01700"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HIR1229637.1"
                     /translation="MGGFFGVTSKTNCTLDLFFGVDYHSHLGTRRGGMAVYGPDGFNR
                     SIHNIENSPFRTKFERDVDELTGNLGIGCISDMDPQPLLIQSHLGSYAITAVGKISNE
                     QELVKEAYEKGHIHFLEMSGGKINATELVAAIINQKESIVDGLLYAQERIKGSMSILI
                     LTPEGIYISRDRLGRTPAMIGKKEGAYCVSFESFAYINLGYKDCHELGPGEIVFMTPD
                     GFEILSKPREEMKICSFLWVYYGYPTSTYEGVNVEAMRYACGKMLAKRDHSDADLVAG
                     IPDSGIAHAVGYANESGIPFARPFIKYTPTWPRSFMPANQNQRSLIARMKLIPVDTLI
                     RNKSLLLIDDSIVRGTQLGETTEFLYESGAKAVHIRPACPPLMFGCKYLNFSRSNSEM
                     DLITRRIIREREGENVSEELLADYANPDSTNYKEMVEEIRKKLNFTTLQFHRLDDLVE
                     SIGISPCKLCTYCWSGKE"
     gene            complement(33063..33404)
                     /locus_tag="ACZPCR_01705"
     CDS             complement(33063..33404)
                     /locus_tag="ACZPCR_01705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3870 domain-containing protein"
                     /protein_id="HIR1229638.1"
                     /translation="MKYEKNTILIVGQAKPSREDAIYSLHGEFYISLVLEKKSGTIIN
                     MDCNTILGVTRDFVADMIVGKSLKTDMELLEKEIRSRYFAMTQKPLIACLKDACNRYA
                     MVLEKEREKEK"
     gene            33717..34604
                     /locus_tag="ACZPCR_01710"
     CDS             33717..34604
                     /locus_tag="ACZPCR_01710"
                     /inference="COORDINATES: protein motif:HMM:NF025694.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4392 domain-containing protein"
                     /protein_id="HIR1229639.1"
                     /translation="MTFFSKLNSIMRQDFGSRGLMKALPEADLDLVSRELAQARRVLI
                     LTGFPVICPDQTVTGETDGPLGTADLAFALEANGCQVMAVTDCHSSAILKAALSVRCR
                     EARIAVIPETGAESFAEDLLDAFSPTHVVTLERPGKACDGHYHNMRGIVIDSMTADAD
                     CFLSLAREKNICTISIGDGGNEMGMGAFRKEIESFVPLGSEICSQQGADYALASGVSN
                     WWGIGAAALLSRETQKFLLPDEEQETEMLRRVLQAGGADGATGLREMTVDRLPLAVHL
                     EILKEVSSLVLEELKLGAA"
     gene            34634..35542
                     /locus_tag="ACZPCR_01715"
     CDS             34634..35542
                     /locus_tag="ACZPCR_01715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008399013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HIR1229640.1"
                     /translation="MEINYDYYRIFYYVAKYKSFTQAAHVLLNNQPNITRSMNNLENQ
                     LGCQLFVRSNRGVELTPEGERLFSHVSIAYRHLQAAEMELGQNRELQSGSVSVGVSSS
                     AFHEVLLPKLIKFHSLFPGIRLRLVSADKTQAVLLLKKERIDFALSALSEEPEKTESP
                     FRETPLKEFREVLIGSRQCSFLADRPRYPAELSGFPLITLGRSAESFEFYRSFYQSLG
                     FSPVPDIEASSAEQMLSLIQNGLGIGFLSERLAETALSSGCVVRIPLAKEPPARRCSL
                     IEDSSRPLSQPAAQLVNLLLEQEKTE"
     gene            complement(35645..37237)
                     /gene="pckA"
                     /locus_tag="ACZPCR_01720"
     CDS             complement(35645..37237)
                     /gene="pckA"
                     /locus_tag="ACZPCR_01720"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004612 - phosphoenolpyruvate
                     carboxykinase (ATP) activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HIR1229641.1"
                     /translation="MKENHSLEMIGIQNTTGKVHYNLNPARLVEEALRRGEGVLTNTG
                     ALSVTTGKYTGRSPKDKFIVDTKDVHDKIAWGDVNVAISEDAYQSIKNKMFTYLADKE
                     LYVFQGFAGADKKYTRKFMVVNEFASQNLFIHQLLIRPTAEELESYGAADFTLVVAPG
                     FTCDPAVDGTHSEAAIIVNFQEKIVLIAGSQYSGEIKKSVFSVMNYLMPVEENVLPMH
                     CSANMDPETHETAIFFGLSGTGKTTLSADPARKLIGDDEHGWCDNGVFNFEGGCYAKC
                     INLDPKNEPEIYNAIRFGSEVENVVIDPETRIPDYDDDSITENTRVGYPITYIDNAQI
                     PGVGGVPKVVIFLTADAFGVLPPISRLDENAAMYHFVTGFTSKLAGTERGIKEPQPTF
                     STLFGEPFMPLNPSVYAEMLGERIRKYNTKVYLVNTGWTGGPYGVGSRMKLSYTRAMV
                     TAALNGELEKAEYKHDDVFNVDVPQSCPGAPAEIMNPRDTWADKAAYDEAAAKLAKMF
                     KDNFDKKYPDMPEEIKNAGPRA"
     gene            complement(37467..38585)
                     /locus_tag="ACZPCR_01725"
     CDS             complement(37467..38585)
                     /locus_tag="ACZPCR_01725"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002568531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HIR1229642.1"
                     /translation="MADLKMVEDLTNAFGPSGFEEEVVQAVKKHSGSLYLEHDAMHNV
                     YAYMDEAAKKRCMPEADRKRPVLMLDAHSDEVGFMVQNIEENGLLDIICLGGIHNTNI
                     PAHSVIVKNRAGKKIRGITTSKPVHFLTAAERADNSLNIEDIRIDVGASSRREVMEDY
                     GVAVGDPVMPDVKFEYDEDHGICYGKAFDNRLGCVSILSTMKALQAESEQLAVEVVGG
                     FAAQEEVGTRGAQVTSQQLLPDLAIVFEGSPADDFYFRPGIAQCSLKAGTQIRHMDAS
                     YVSNPEFIRLAQEIGDKCGIKYQDAVRRGGSTNAGKISLTGKAVPVLVLGIPSRYVHT
                     HYNFCAMEDIDATVKMAVEVIRSLDKERIDIVMRRGII"
     gene            complement(38632..39432)
                     /locus_tag="ACZPCR_01730"
     CDS             complement(38632..39432)
                     /locus_tag="ACZPCR_01730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HIR1229643.1"
                     /translation="MKLFISADIEGCVGTTLASETHKETPEYRQFAKRMTDEVRIVCQ
                     AALEAGAGEIVVKDGHGDATNIDFTAMPEGVTLIRGKSGHPYNMMFGLDETFDGVLYV
                     GYHAPAGNGGNPISHTSTGNSNQILLNGKVMSEFMLNTYTAAMMGVPAVFISGDEGIC
                     GLAREMVPGITTAAVKKGVGACTINMSVAAADRLLKEKVKEALSGDLKACRIAMPEQF
                     EYVVNYKDLKKAYQMSFFPGAERVDERTNRVVSRDYKDIVTAHSFMVY"
     gene            complement(39468..40457)
                     /locus_tag="ACZPCR_01735"
     CDS             complement(39468..40457)
                     /locus_tag="ACZPCR_01735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1229644.1"
                     /translation="MAEDLLKVEGLKQYYPVSDGLFGTKAFVKAVDGVDFEVKKGEVF
                     GIVGESGCGKSTLGKAICKLIEPTDGKIILDGEDIRGYNSKKMRNVRKKVQMVFQDPY
                     ASLNPRMSIHDILAEPLQIHGLVKGKQEIDEAVVRLLREVGMDDYHARRYPHEFSGGQ
                     RQRIGIARALAVRPQLIIADEPVSALDVSIQSQVLNLMSKLKKEYHLTYIFIAHDLSV
                     VEHISDRIGVMYLGNFVEKANKENLYKNPMHPYTQALLSAVPIPDPTVKKERIILEGS
                     IPSAINPPSGCKFHTRCPKCMEICKKEAPKKYQVGEDHFVYCHLYDKENPNVK"
     gene            complement(40470..41447)
                     /locus_tag="ACZPCR_01740"
     CDS             complement(40470..41447)
                     /locus_tag="ACZPCR_01740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009263756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1229645.1"
                     /translation="MDTRKNILEIKNMHTYFFTDNGVVKSVDGVDIELKEGSTLGIVG
                     ESGSGKSVTALSVMGLLMGTTGKVVEGQILLDGRDITNLSAEERRKIRGNQISMIFQE
                     PMTSLNPVMKIGDQLVEAIKMHQNKTKEEAQSMAVEMLKKTGLPRVERIVNEYPFQLS
                     GGQRQRVMIAMALVCNPKILIADEPTTALDVTIQAQIIDLMNHLKKEIGTSIMFITHD
                     LGVVAETCDEVVVMYCGRVVEKGNVYDIFGKTAHPYTQGLLKSIPKLGEHVEELDSIP
                     GNVPNPKYMPKGCKFAPRCAYATERCKEEEPGFFDLGNGHQSRCWLCDK"
     gene            complement(41476..42354)
                     /locus_tag="ACZPCR_01745"
     CDS             complement(41476..42354)
                     /locus_tag="ACZPCR_01745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HIR1229646.1"
                     /translation="MAKEKVLNEKMDINTPFKDFVRKFKKQKTAIAAMFFIIALAVLA
                     VVSYQIAPYGINEYDYTAIMQGPSAAHWFGTDEFGRDLFSRIICGTRISLSVGLFSVS
                     IAAVCGTILGLLGGYYGGLLDSIIMRICDTLFAFPGIILAIAIIAILGSGMTNVVIAV
                     AVFSTPTFARLVRSTTLATKGNVFVQAAKNLGASDARILFRHILPSAIPNIIVQYTMS
                     IGTSILTASSLSFLGMGAQPPTPEWGLLLSNGRTYMATSWHITLFPGLAIFLTVLCFN
                     LLGDGLRDALDPKLTD"
     gene            complement(42373..42774)
                     /locus_tag="ACZPCR_01750"
     CDS             complement(42373..42774)
                     /locus_tag="ACZPCR_01750"
                     /inference="COORDINATES: protein motif:HMM:NF012738.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1229647.1"
                     /translation="MLPSIALGTSIAAIIARFTRSSIIEVMKEDYIRTARAKGLKERT
                     VIWKHAFRNAMISVVTVVGLQFGFLLGGSVVTESVFAFPGLGSLLVESVNYRDYNAIQ
                     SLILIFSLHFVVINLVVDILYALLNPEIKLN"
     gene            complement(42821..43297)
                     /locus_tag="ACZPCR_01755"
     CDS             complement(42821..43297)
                     /locus_tag="ACZPCR_01755"
                     /inference="COORDINATES: protein motif:HMM:NF040248.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease family protein"
                     /protein_id="HIR1229648.1"
                     /translation="MLKYIIKRIIGVIPTLIIVTTFVFFFVRLIPGDPARLVAGPQAT
                     LEDVEVVREELGLNKPIVTQYVDYVTGLFHGDLGMSLRTKRPVATEVSLRYMNTVKLT
                     LGSLAWSVVVGVLLGVWSGKHRSKWQDYTGMTMAISGISMPSFWIGFLLIMVCLLR"
     gene            complement(43407..45128)
                     /locus_tag="ACZPCR_01760"
     CDS             complement(43407..45128)
                     /locus_tag="ACZPCR_01760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002577682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter substrate-binding
                     protein"
                     /protein_id="HIR1229649.1"
                     /translation="MKLRAKRLLALAMAGVMALSMAGCGGSGDSGKETTGQTGESKAP
                     AGEGAGTQAEIPVSAAEVTVPAGESVSQETDVVGAILVDFTTMDPMDTSDTLSGGIQR
                     MMMDGLFGFDDNMKIIPMLATDYEANEDATEYVIHLRQGVSFTDGTPFNAEAAKANLD
                     RWADKELGLKRTTLLCNVIGSTEIVDDYTVKVKLSQSFGAFISTLAHPACVLMSPKVI
                     AEGNDACAERPVGTGQYIFKEWIAGDHATVTLNKDWWGYDAEICGGTALAEPDAGFKS
                     VTFRPVAENATRVAMLQSGDADFIWPVPTESMQALAGDTNIYVGAEEGMVVRYLFMNN
                     QKAPFNDKRVRQAVNYAINKDAYIAVVKNGLSSAASSIIGPATQHYKGNDPYPYDPEK
                     AKELLAEAGYPDGFECTLICASTTGNLKQGEFLQQQLAQVGITMNINALESAVVNDKV
                     ENVDKPGAEAEVEMYVIGWSSSTGDADWGIRPLVAVESEPPMSYNICYYENEEVDKLL
                     YDALSTADETKRAEFYAQAQDILWEDCPMVCLVNDYNTWATTNKIANVKVYPDNCLNI
                     RNARMAK"
     gene            complement(45325..47070)
                     /locus_tag="ACZPCR_01765"
     CDS             complement(45325..47070)
                     /locus_tag="ACZPCR_01765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002577682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter substrate-binding
                     protein"
                     /protein_id="HIR1229650.1"
                     /translation="MQDKALAGSAAGSMALFMTACGSSETGNGNASQTQESGTGAGNG
                     KEGTTAQTGTEQAAAETALPVSKTEPSVPEGASVSQKTDVTAAMSVDFMTMDPMDTSD
                     TLSGGVQRLIMDGLFGFDDEMKIIPLLAESYEANEDATEYVIHLRQGISFSDGTPLNA
                     EAAKANFDRWGDKELGLKRTTLLCNVLKSTEAVDEYTVKVTLTEPFGAFVATLAHPAC
                     VLMSPQVIEQGKEACAERPVGTGQYLFKEWIAGDHTTVTLNKDWWGYDPEICGGKALA
                     EPDAGFQSITFRPVGENASRVAMLQSGEADFIWPVPTESMETLAADENVYVGADEGIV
                     VRYMFMNTQKAPFNDVRVRQAMNYAIDKDAYIAVVKNGLASKATSILGPATQHYKRNE
                     PYAYDLEKARKLLTDAGYPDGFETSLICTTTTSDLKQCEFIQQQLAQAGITVNINSME
                     KAIVSEKVESAEGPGSEVEVEMYMSGWSSSTGDADWGIRPVLAKESEPPKSYNISYFE
                     NDEMDGCLKAALETADEEKRAELYAKAQDIIWEECPVVFFANDYNTWASAADVANVKI
                     YPDGGLNIRNARMNP"
     gene            47347..48075
                     /locus_tag="ACZPCR_01770"
     CDS             47347..48075
                     /locus_tag="ACZPCR_01770"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008398248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016811 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in linear amides
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HIR1229651.1"
                     /translation="MTKKPLIGIITILDAQAVPRVSVNINYQNAVIRAGGVPILLPVT
                     REEELLAGYADMCDGFLFSGGQDISPCRYNELPSRLTGPSSLLLDDYQLNLMKLVLDS
                     KKPFIAICRGIQVLNVACGGTLYQDLTEFSPTVSKHMQETDRGDVSHPVTIQEGTRLH
                     SLFGDRIWTNSYHHQALKRVPGSLKVAAHSDDGVVEAVEVRDYPFGIGLQWHPEAMLA
                     SDDAMLPLFQAFIQAAGDRQDTGK"
     gene            complement(48185..49288)
                     /locus_tag="ACZPCR_01775"
     CDS             complement(48185..49288)
                     /locus_tag="ACZPCR_01775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HIR1229652.1"
                     /translation="MKKRICDYGISIGEHPKGKRNKITDVPGVKVGHRTLEREGIHTG
                     VTVILPVEDNIFLNKCTAAAYVHNGFGKTCGLPQIEELGTLETPIALTNTLNVGLVAD
                     ALVEYTLKRCEADGAEASSVNPVVGECNDSRINRISLRAVKKEDVFSAIDQAGEEFEE
                     GCVGAGAGTLCYGFKGGIGSASRVVAVGEKEYTIGVLVQSNFGATRFLTIDGRPVGRE
                     ILAAADGREDPARPFPSEQARTAVKNSMFRGTEEDRGSIMMICATDLPLSERQLRRLI
                     RRMCNGLARTGSYTGHGSGEVMIGFTTAGRVPDGKEPAVLEHRCLNENLMDGPFQAVA
                     EATEEAVLNSMTAAVTTKGLDGTVYYSLAEFLQ"
     gene            49423..50028
                     /locus_tag="ACZPCR_01780"
     CDS             49423..50028
                     /locus_tag="ACZPCR_01780"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229653.1"
                     /translation="MKYLNQLEYPSIPYPTDISHPGSPLNSGSVKEAGCGLCCLAMAV
                     DRLTDQSVSLKKLVSLSVKHKANLLPGTDMEILGPVVARQFHLEYSTTESVRTAVRCL
                     KRGGCVIANVGGDREGYTGVFAHEGHFILLIASDGDQICVLDPALRPGRYDEPGRRGK
                     VLLDEPFAWCSLKLLTKETDNRSPGFYLFYRKAPLAAGKVL"
     gene            complement(50182..50472)
                     /locus_tag="ACZPCR_01785"
     CDS             complement(50182..50472)
                     /locus_tag="ACZPCR_01785"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229654.1"
                     /translation="MKAYDVQAKAEVEVTVEDLMKLLDSNRQVDLVFSEPRTDEDGYL
                     TWDRENWLLVKEGKYQRNYFLNGKALYDFTHHNKYDMKNSFFPDQAEKIELN"
     gene            complement(50519..51928)
                     /locus_tag="ACZPCR_01790"
     CDS             complement(50519..51928)
                     /locus_tag="ACZPCR_01790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase-like domain-containing protein"
                     /protein_id="HIR1229655.1"
                     /translation="MADKTALDMRYLNVPLPEDLMKLKWGGDYERLISVIDRRLADET
                     LPAPLRKRLQLERILAARIPSQYPYSYEEALALLRANIRDFKDKELETLWEENTADWI
                     YINGRVQFHELFFENLMKTRDDYGARFLGTMEDNEKNAALLRENVRLMEEHGGRTVHM
                     RLLTRLSLTPEAEKACMGKTAHVYMPLPVEYAQVRNLRLLGFEGTAGEPVSVDNGSYP
                     QRTARFETVIRGGEVWQTEFEFDNETVFRNPDPSQVLFSQPSFYTGEEAPHIRFTPYL
                     RELTRSVTEGEENPLLAAEKIYRFITSQVKYSFVRSYSTVEDIPEFTAANRKGDCGFQ
                     ALLFITMCRIAGIPARWQSGLYATPLTVGSHDWAQYYVAPFGWLSADCSFGGSAFRQG
                     DEKRRAYYGANLDPYRIPYASQFMHSFSREEEGLRDDPYDNQSGEVFCGGRFLRSGKE
                     FTVEYRLETAEKPFDGTGK"
     gene            complement(51993..52979)
                     /locus_tag="ACZPCR_01795"
     CDS             complement(51993..52979)
                     /locus_tag="ACZPCR_01795"
                     /inference="COORDINATES: protein motif:HMM:NF036878.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN domain-containing protein"
                     /protein_id="HIR1229656.1"
                     /translation="MSTYLVDFENVGVGGMDGVEKLSDRDRVVIFYGKQAAAVPFERH
                     IEIASSRAEVRYIKVDKTGKNFLDFQLSSYCGYLIGSTSEKEFIIVSRDNGFGSMEDF
                     WHGKEMSGKKISMKRRPAIAASGEELESVREIIVDKGERQAQPSGEPAKEKESSRQAE
                     EGQNRRNRRNSRNNRNNRNQGRPQPEGPIKIQTISAENRKQETEPLREQKENKACEEV
                     GREKKQEERRGPEPAKEGAPKRRSKKRTGWTDDRREQGGQKEKKALIQEESSTERPAV
                     QEQEKQPESEKRPETAAEQSGASQKQEGIQERRPYRQSRRRPRGRYVWNRQK"
     gene            complement(53033..53965)
                     /gene="metA"
                     /locus_tag="ACZPCR_01800"
     CDS             complement(53033..53965)
                     /gene="metA"
                     /locus_tag="ACZPCR_01800"
                     /EC_number="2.3.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004414 - homoserine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-acetyltransferase MetA"
                     /protein_id="HIR1229657.1"
                     /translation="MPIKVQKDLPAKAVLESENIFTMDEDRALSQDIRPLEILILNLM
                     PIKEETETQLLRALSNTPLQVDCTFLMLASHNSKNTSASHLNKFYVTFDEVKKRKFDG
                     MIITGAPVENMEYEEVNYWPELTAIMEWSKTHVTSTLHICWGAQAGLYYHYQIPKYRR
                     ERKLSGIYEHQVLNRKVPLVRSLDDSFYCPHSRWTEVREEDVKKNPELMILAKSREAG
                     IFLVMSRDGRQIFMQGHPEYDRMTLNNEYHRDLKKGMNPEIPYNYYEDNDPFSIPALK
                     WRNMANTLYTNWLNFYVYQVTPYLLESDGAEAEE"
     gene            complement(54039..56036)
                     /gene="ligA"
                     /locus_tag="ACZPCR_01805"
     CDS             complement(54039..56036)
                     /gene="ligA"
                     /locus_tag="ACZPCR_01805"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016291364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HIR1229658.1"
                     /translation="MNQEQKIERMKELIELLNRAGRAYYQESREIMSNFEYDRLYDEL
                     AGLERETKTVFGNSPTQNVGYEVVSSLVKERHEKPMLSLNKTKSVEELKEWLGNEEGL
                     LSWKMDGLTIVLTYEGGELRKAVTRGNGEIGEVITANARTFVNVPKTIPYTGQLVLRG
                     EAVIRYSDFLKINEEIEEIDARYKNPRNLCSGSVRQLNSQITAQRNVRFFAFSLVMAE
                     GVEFENSREKQFLWLQSQGFETVEYRRVTADSLEEAVAGFSRLVEKNDVPSDGLVLLF
                     DDIAYGQSLGRTAKFPRDSIAFKWADEIQETTLSYIEWSASRTGLINPVAVFEPVELE
                     GTTVTRASVHNLSIMESLELGEGDRITVYKANMIIPQIADNLTRSGVKNIPCTCPVCG
                     GATEIRQVNDVKSLYCTNPDCQAKKLKSFALFASRDALNIAGLSEATLEKFIGRGLIH
                     EYADIFHLDAHEAEIVEMEGFGKKSFDKLCEAVKKASHTTLPRVIYGLGVAGIGLANA
                     KMLCRHFKYDFQAMRNADKEELVAVDGIGEVLAEAWIQFFQNEKNNKITDRLLAELLL
                     PPAPEEEEETGAGSGLAGLTFVITGSVERFKNRKELQELIEERGGKVTGSVTAKTSYL
                     INNDSASSSSKNKKARELNIPIITEDEFIGQFIPGSSAETA"
     gene            complement(56154..56954)
                     /locus_tag="ACZPCR_01810"
     CDS             complement(56154..56954)
                     /locus_tag="ACZPCR_01810"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002603185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HIR1229659.1"
                     /translation="MKKRVVIDAGHGGTTDPGAVYFGRQEKDDALKLALAAGDLLEDR
                     GFDVMYTRVDDVYHTPYEKADMGNSAGADYFISIHRNAAGIPGTASGIMTLVYEDAGV
                     NGRLARAVNEELEKTGYQDLGVVERPGLAVLRRTAMPAILIEAGFIDNPQDNQLFDQQ
                     FEAIAEAVADGVEKAVREEEKRELPVYYMVQTGAYRLRSLAEQQLAELQSQGYPAFLV
                     YDNGYYDVRAGAFLNLDYAAALEEELRSRGYNTFIVKDYSTEDKKKLE"
     gene            complement(57038..57850)
                     /gene="dapF"
                     /locus_tag="ACZPCR_01815"
     CDS             complement(57038..57850)
                     /gene="dapF"
                     /locus_tag="ACZPCR_01815"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005951329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HIR1229660.1"
                     /translation="MKFTKMQGIGNDYVYVDCFQETVEDPGKTAVFVSDRHFGIGSDG
                     LILIKPSTVADCQMDMYNLDGSRGAMCGNGVRCVGKYAYDHGIVPPERTTLTVETASG
                     IKTLKVQAENGKARELTVDMGKPEMTSELFEPIAVEGEEYRFIGISMGNPHAVLFVDN
                     TAAVPLETIGPKFENHSRFPDRTNTEFVEIVDRGHIKMRVWERGSGETMACGTGACAS
                     AVASILAGYTDTKVEVELLGGSLTIEWDREKDTVYMTGPAEEVFSGEIDLKF"
     gene            complement(57980..58858)
                     /gene="dapF"
                     /locus_tag="ACZPCR_01820"
     CDS             complement(57980..58858)
                     /gene="dapF"
                     /locus_tag="ACZPCR_01820"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009263605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HIR1229661.1"
                     /translation="MKAVFEKYHCMGNDYLVYDPNKNEMELGPEQVKAVCDRNFGIGS
                     DGILVGPVLGGEKMYVRILNPDGSEAEKSGNGMGIFARYLKDAGYVQKTKVSWDTLGG
                     EVTVYYLNEEGTRVKISMGKPTFWSDEIPVTGERREMVNQTMVFGKIPYITTCLSIGN
                     PHCVIWMNEISKELVCRIGEHSERDSSFPEKVNTQLLNVLDRTNIQIEIYERGAGYTL
                     ASGSCACAAACAANRLGLADRNMYVHMPGGTLEVEIKEDGIVYMTGEVGYIGRMTLGS
                     EMVERLRQSKETNPSK"
     gene            59053..59949
                     /locus_tag="ACZPCR_01825"
     CDS             59053..59949
                     /locus_tag="ACZPCR_01825"
                     /inference="COORDINATES: protein motif:HMM:NF014376.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HIR1229662.1"
                     /translation="MALLNDKRDEDCEKRGYLFEEFRLFHLSDPVTEPIGYHYHDFHK
                     ILFFLRGEAGYSVEGASYDLAPGDIVLIPRYSIHRPEICPGASYERVILYLSPDLLTG
                     SLCGPEHLAGLFQAASDSRSYVLRLPRLCQAELLEALSRLETSCRESGFADGLLRRLI
                     LLELLILLNRACQSPESRRLPASSKNAAVLSIMQFIHDNSDSDLTIDGLASRFYMSRA
                     HMMRLFKRETGYTIGGYINEKRLLTARQLLDQGLSVTECCYRCGFKNYDAFLRAYKKS
                     FGETPKRKKQPSSLISPHCGTR"
     gene            complement(59921..61048)
                     /gene="ytvI"
                     /locus_tag="ACZPCR_01830"
     CDS             complement(59921..61048)
                     /gene="ytvI"
                     /locus_tag="ACZPCR_01830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HIR1229663.1"
                     /translation="MEGVKKYLRIILNIIIPLTGLYLVCVWGPRVLGFFIPFVIGWMI
                     ALIANPLVRFLEKRLKIVRKHGSMLIIAGVLALIISLLYFVLGKAYVEIREFIGDLPA
                     LYDSAAAEIRGAVQNGNRMFEFLPDEFRTAVMQFTENIGTYVGDLVSKAAAPTVEIAG
                     NVAKGIPNVLVNTVITILSSYLFIAEQDKILAWMRRYAPKFVLRYAEYLKKDARGVIG
                     GYFLAQFRIMFVVAGILAVGFLFLKVKYGLLLAVLISMLDFLPVFGTGTALFPWAAVK
                     LFTGEYTYAAGLLILYVVTQVSRQLIQPKIVGDSMGLPPLLTLFLLYLGFKVKGIAGM
                     ILAVPIGLIFINFYKYGAFDSLIENVKLLIRELNAFRNGER"
     gene            complement(61131..62327)
                     /locus_tag="ACZPCR_01835"
     CDS             complement(61131..62327)
                     /locus_tag="ACZPCR_01835"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006779976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HIR1229664.1"
                     /translation="MISEKMQPLLQNNSAIRMMFEEGRKMAAVYGADQVYDFSLGNPS
                     VPAPAEVNQAMREILEEEDSLFVHGYMSNAGYEDVREAVAQSLNRRFDTSFSQSNILM
                     TVGAASGLNVILKTLLNPGEQVMVFAPYFVEYGSYVRNYDGELVVVSPNTETFQPNLR
                     EFEERICEKTKAVIINTPNNPTGVVYSSETLQALAEILERKSAQIGHPIVLISDEPYR
                     ELAYDGVQVPFMTKYYRNTVICYSFSKSLSLPGERIGYLVVPDEMDEAEQVFNAAVIA
                     NRVLGCVNAPSFMQRVIKRCIDAKADVAAYDRNRNLLYEGLKSFGFECIRPEGAFYLF
                     MKTPGDEKEFCERAKKYHILVVPGSSFACPGYVRIAYCVSYEQIERALPEFKKLAAEY
                     GLPGEE"
     gene            complement(62359..63678)
                     /locus_tag="ACZPCR_01840"
     CDS             complement(62359..63678)
                     /locus_tag="ACZPCR_01840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008755 - O antigen polymerase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polymerase"
                     /protein_id="HIR1229665.1"
                     /translation="MIVYLICCLASFLLARGEHFYLSGLCLMGAAVFLYVQDFRRTGN
                     CIHLRGIFALAWVGGQGVSCLKLSRLAQDWTFLTWLCFLAAFVSFYAVFEVFERRGRN
                     NYNSYASRWKGQKRWHDFRSCEEPVFICALAVTALSLFCFVLEAVVLGYVPFFLRGVP
                     HAYSYFHITGVHYFTVSCVLVPALSVIFFHSNGGRDRLRTGILIGADIIAVLIPILCV
                     SRFQLILAAVLAVITYLMMDIHIDPLQMIISAAVLFVGLLAAYIILTIARSHDVEYLN
                     GIFEMKNSRTPIFVTQPYMYIANNYDNFDCMVRAMASGYSHSFGLKMLFPLWALTGLK
                     FLVPSLTAFPLFTTKEELTTVTLFYDAYYDFGILGVVLLGCVLGLLAWYLTDMVKHIR
                     NPIGYLLYAQIAVYFGLSFFTTWFSNPTTWFYLAVTGAAAVYVEWRQ"
     gene            complement(63813..65531)
                     /gene="ptsP"
                     /locus_tag="ACZPCR_01845"
     CDS             complement(63813..65531)
                     /gene="ptsP"
                     /locus_tag="ACZPCR_01845"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013271949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HIR1229666.1"
                     /translation="MVSGTGASAGIGIGRVVILKEETLEIKRETIADAEAEKARFKKA
                     VEKSIEDTKALADDMAQRIGEKEAEILNGHLMLLQDPMMTMEIEGKIDGEKLCSEAAV
                     EDVCTMYADMFASMDDELMQQRAADMRDIKTRMQKVLLGVQSVDVSSLPAGSVLVSED
                     LTPSVTAGINPANVTGIVTELGGRTSHSAILSRALEIPAVVAASGILSQVKDGDEIIL
                     DGETGEIFLQPDESLKAEYEAKQAVYLKEKEELKKYIGKETITKDGVKIETAANIGRP
                     EDVDRVLSYDAEGIGLFRTEFLFMDRTAMPTEEEQFEAYRKVAVAMDGKPVIIRTLDI
                     GGDKEIPYMGLKKDENPFLGYRAIRFCLDRKDDIYRPQLRALLRASAFGAIKIMIPMV
                     TCVEEYREAKALIQEIMEELDEKGIAYNHNIQVGIMVETAAASLMADVFAKEVDFFSI
                     GTNDLTQYTMSVDRGNDKVSYLYSTFNPAVLRSIRHIIECGRKEGIMVGMCGEAASDP
                     LMIPLLVAFGLNEFSMSASAVLKARKMITECDSRELQEMAGKAMSFATAGEIESFMRE
                     FVSRNF"
     gene            complement(65562..65825)
                     /locus_tag="ACZPCR_01850"
     CDS             complement(65562..65825)
                     /locus_tag="ACZPCR_01850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006856693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HIR1229667.1"
                     /translation="MVKAKVTIKNTSGLHLRPAGILCNEAVKYQSQITFSHKNNVSNA
                     KSVLSVLGACIKCGDELEFICEGKDEEEALSAMLKAVNDGLGE"
     gene            complement(65849..67237)
                     /locus_tag="ACZPCR_01855"
     CDS             complement(65849..67237)
                     /locus_tag="ACZPCR_01855"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HIR1229668.1"
                     /translation="MKEKLTKNATLKLISLLCAFLVWLAVVNVANPIQTKSIEIPVNI
                     TNDEVLESSNLTYEIEGKSTVTLLINARARDIYRFTSEDFKAYADLSELYSVTGAVPV
                     TVEVLDDEQYLASNGEGVKYEVKAPGTVHIKTEELQTKRFSLTHHVTGDPAGNRDYLP
                     GKVKLTPNYVYVRGPVSQIGQISSVGVEINIEGKDSDLSGTAVPKFYDANDNELTLSS
                     AVTVLGGDISYELTMLKVKNLALDFQVSGQVADGYRLTGVECGVDSVSVAGLRSVLAN
                     MNTLPIESPQLSAEGLTGDKECVIDLEEFVPPGLELAGMDSTSVTVTLKVEPLENRTY
                     TLDDNDIELVGASEEYTYELADGTVPLTVRGLKEDLNSLSPDKMNLKADVSGMKPGTH
                     TAALSYQLDEAYTVAGTPSITLEVKAKAPETEAETQEEDVRASSESAEAVPENSQQKQ
                     EPSSAAAGSQNQ"
     gene            complement(67218..68090)
                     /gene="cdaA"
                     /locus_tag="ACZPCR_01860"
     CDS             complement(67218..68090)
                     /gene="cdaA"
                     /locus_tag="ACZPCR_01860"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HIR1229669.1"
                     /translation="MAEYVKELYSWIAFVPNMTFKNFLEIGIIAFVVYEVLVWIKNTR
                     AWTLLKGILFICGFVLMAAVLELDTILWLLGKASYITITALIIIFQPELRKALEQLGS
                     KNVLTGIFTADDGKVKEGFSEKTINELTRACFEMGKVKTGALMVIEMETPLTDVERTG
                     IEVDGIITSQLLINIFEHNTPLHDGAVVIRGNRVTAATCYLPLSDNMDISKALGTRHR
                     AAVGISEVTDSLTLVVSEETGRVSVATGGRLLRVADADELRGILARAVRNEENSSGRF
                     KIWKGRRKNERKAD"
     gene            complement(68124..69071)
                     /locus_tag="ACZPCR_01865"
     CDS             complement(68124..69071)
                     /locus_tag="ACZPCR_01865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008397452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1229670.1"
                     /translation="MMGLLVFKERLRIFYAKNSQIVIPAVKFAVAFMAFYLIGKNTGF
                     VEKLNSSLMPAVMGLVGAAVPYGVTAFLAGAFLMAQLFAVSLEVAAITLVFLMIVVLL
                     YYGFQPGDSVLLLVTPIMFFLKIPFAVPLLVGLGGSMLSVIPVSCGAFLYYVILYVKQ
                     NASVLSGSAQTELTQLIIQLVKSLVTNQAMLIMVAAMALCILLVHTIKNMPINYAWGI
                     AIAAGVIVQLLVIFIGDLRFDASVSVLEVTAGMAVSAAAAAVYHFFVFAVDYTRTEYV
                     QFEDDDYHYYVKAVPKIAVSKPDVKVQRINTRKTPRRRD"
     gene            complement(69068..69496)
                     /locus_tag="ACZPCR_01870"
     CDS             complement(69068..69496)
                     /locus_tag="ACZPCR_01870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229671.1"
                     /translation="MLNEDKIKLMTSMAMFEKKNGKAMNAGKNYFKSDYVSRQMIRGF
                     FSYTISCTAVLFIWLLYSMEQFLSTLSFEGMLGLIRNFVIYYLIGLAVYMGLVHTVYS
                     RRYDYAAKNIRLYTAKLKHLDKRYDYHNRSRTLAKEDRRV"
     gene            complement(69693..70913)
                     /locus_tag="ACZPCR_01875"
     CDS             complement(69693..70913)
                     /locus_tag="ACZPCR_01875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002595985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1229672.1"
                     /translation="MLIENMKMAFTALRANKMRSFLTMLGIIIGIGSVISIVSIGDTM
                     RELFSSLYQDVGLTQTYVGIGYWIDDVRESDYFTMDDLSRIKEVFGDDIAYIDSGASA
                     SAEAVSGPDKMQFNYTGIDWNYNEVQPVKMLYGRYLSEADIKGRKEHAVIDIDTARNF
                     FHTDNPVGRTFRTVLYGEMKEFTVVGVYEKEMSPFQELMMGGGSDKGSAFIPWTVLTW
                     PNDEFYYCHLFARESMTSSQLERFYDELVFYISKLKNRNPEDWYVESAVEQMGQVDSM
                     MAGLSVAVGGIAAISLVVGGIGIMNIMLVSVTERTREIGVRKALGARTKDILIQFLTE
                     SAILSACGGLVGIITGGGIVMAAGAALGVEAVIKPSVVILAVTFSAVVGIFFGLYPAR
                     KAAISNPIDALRYE"
     gene            complement(70903..71574)
                     /locus_tag="ACZPCR_01880"
     CDS             complement(70903..71574)
                     /locus_tag="ACZPCR_01880"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1229673.1"
                     /translation="MKVIGLRNINLTIRRGEFVAIMGQSGSGKSTFMNILGCLDRPAI
                     GHYYLDGIDINAMDDDQLSLIRNKKIGFVFQSFNLISRTTARENVELPMTYAHIPKRE
                     RSERAVKLLERVGLGARTEHMPNEMSGGQRQRVAIARALANDPPLILADEPTGNLDTA
                     SSIEIMELFSELHREGATVVVVTHEEDIASFTQRIIRFRDGQIISDEKNEAWKCREGR
                     KTDAD"
     gene            complement(71703..73067)
                     /locus_tag="ACZPCR_01885"
     CDS             complement(71703..73067)
                     /locus_tag="ACZPCR_01885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009295799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1229674.1"
                     /translation="MEEHKNTSYASPKSGEEVERELEAYINEPKNGKRRRLSLSGAVR
                     AIRGQSPKKKRIEAVLAVAAAVCLAVRYTAGGSTLSQVPSMALAKGDVVSSLSLTGPV
                     SGTDSADVVSNLHSEVLEIRVKEGDTVEKGQVLAVIDRTDAQKEVDVAQNAYDLAVSE
                     YNESLRDTKIGYEKAKQDYSTASLNYERNKTLFEAGAISSAEFEAVGNALSDARRAVE
                     GYRMENGQAVPDESYELKVKAAQFELDQKKRDLEDTEVKSPISGTVVRVNSKVGQFAD
                     KPEDEKPMFIIENLAQLEMELQISEYSVGDVSVGLPVDITADILNGKTVTGTITSISP
                     TGEEKTGSASTERVVPATVSIDKEDSGLIAGITARASIVTERAEDVFKVPSSAVRTGE
                     DGSSQIAVLKEGTGIVHFVSVDTGVESDLETEIIPIGEELTEGMTLLLTPDGLTEGME
                     VEPV"
     gene            complement(73191..73826)
                     /locus_tag="ACZPCR_01890"
     CDS             complement(73191..73826)
                     /locus_tag="ACZPCR_01890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III domain-containing protein"
                     /protein_id="HIR1229675.1"
                     /translation="MTKEELTLEVIARLKKEYPLAVCTLDYNDAWKLLVSVRLAAQCT
                     DARVNVVVKDLYAKFPDVDALANAPVEEIEAIVKPCGLGRSKAKDISACMKMLRDQFD
                     SRVPDDFDALLSLPGVGRKSANLIMGDVFGKPAMVTDTHCIRLVNRIGIVEGIKEPKK
                     VEMVLWKLVPPEEGSDFCHRLVYHGRDVCTARTKPHCERCCLSDICAKTGV"
     gene            74030..75394
                     /locus_tag="ACZPCR_01895"
     CDS             74030..75394
                     /locus_tag="ACZPCR_01895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009429872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015851 - nucleobase transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HIR1229676.1"
                     /translation="MEHFFKLKEHGTDVRTEIIAGVTTFMTMAYILAVNPAMLGPDGA
                     GMDSGAVFTATALASAAASFLMAFLANLPFVLSAGMGLNAYFAYTVCGSMGYSWEVAL
                     TAVFVEGIIFILLSLTRVREALFNAIPATLKIAVAVGIGLFITFIGLQNAHIVVASST
                     LVSLFSFRGSMTAGTFSSEGITVLLALIGIIITSVLLIKRVKGNILIGILATWGLGMI
                     CQAVGLYVPNPEMGFYSLFPSGIISMPASVVPTFMKMDFSIVGTLNFAVVIFAFLFVD
                     MFDTLGTLIGCASKADMLDENGKLPKIRSALFADAVGTTLGAALGTSTITTFVESSSG
                     IAEGGRTGLTSVTAGILFLVSLFLSPVFLAIPSFATAPALIVVGFLMMQQVVKIQWDN
                     LTEAIPAFIAVIAMPFMYSISEGISMGVISYVLLHLLTGKAKDNTPLMYILTVLFILK
                     YIFL"
     gene            75545..75615
                     /locus_tag="ACZPCR_01900"
     tRNA            75545..75615
                     /locus_tag="ACZPCR_01900"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:75577..75579,aa:Gly,seq:ccc)
     gene            complement(75872..76756)
                     /locus_tag="ACZPCR_01905"
     CDS             complement(75872..76756)
                     /locus_tag="ACZPCR_01905"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0016019 - peptidoglycan immune receptor
                     activity [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0045087 - innate immune response [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein family
                     protein"
                     /protein_id="HIR1229677.1"
                     /translation="MQINKLLTPYNLNRLGDTNRIRYIVIHYVGATGGAEANCRYYAS
                     KYIGASAHYYVGFGGEIWQSVEDGDIAWHCGAKSYRHPECRNSNSIGIELCVRNKGSQ
                     AADSRDWYFEDATVQAAIELTRELMEKYSIPADHVIRHYDVTGKICPNPYVYNHTSHT
                     WDVFKAAITGEETMWEYQTISTDTAQVEVTASSLVIRDAPGGKDTGGRYYKGNRIKPL
                     RKALAGSERWFLTERGWISADYLQGWIREDGRWWYLRPGYIYPAGRLEVINGRCYCFD
                     FNGWMLTSSRIQEDGEVI"
     gene            complement(76746..76910)
                     /locus_tag="ACZPCR_01910"
     CDS             complement(76746..76910)
                     /locus_tag="ACZPCR_01910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229678.1"
                     /translation="MVKSMQRADLGDKWFTELQKEAREASETALQDFQAAIDPDAMGP
                     DGKEGIDDAD"
     gene            complement(76966..77199)
                     /locus_tag="ACZPCR_01915"
     CDS             complement(76966..77199)
                     /locus_tag="ACZPCR_01915"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229679.1"
                     /translation="MSRTHKCPVHGENGFDQEKAGTHIPEPIADCTCDVGATGPAAEG
                     KGNTPVGPGLEGLGNTPVGPGLGGGNTPIGPGK"
BASE COUNT        17456 a        21918 c        17005 g        20898 t
ORIGIN      
        1 acggttctcc cgaaaatgtt tgtatactct ttgaataaat tatgaagatt ttcttaagat
       61 cgtatcttcc tatgcaataa aatacgctct tcctgcatta taggcgtttc agaggccctt
      121 atttcacatt ttgaaataaa tcgcagaagt caaaggtagc aaaatagtcc ttcggagtct
      181 ctgcccgacg gatcatctgc actgatttgt cttcctttaa cagaagctct gcggaacgaa
      241 gctttccatt ataattatat cccatggaaa agccgtgggc ccctgtatcg tgaatcacca
      301 gcagatctcc catgtcaatc ttcggcagca tcctgtcaat ggcaaacttg tcgttattct
      361 cacagagaga acctgcaata tcatatttat ggtcgcaggg cgcgtcctcc tttcccatga
      421 cagtaatgtg gtggtatgca ccgtacatcg cggggcgcat gagatttacc gcacaggcgt
      481 ccactccgat atactcctta tgcgtatgct tttcatgaat ggcagttgtc accagacagc
      541 cgtagggccc cagcataaaa cggcccagct ctgtatacag agccacgtct cccattccag
      601 ctggaacgag aatctcctcg tacacctttc ttacgccctc tccaatcaca aaaatatcgt
      661 taggttcctg atccgggcgg tatggaatac cgattcctcc ggagagattg atgaaggcaa
      721 tttcagctcc cgtctcctcc ttcaggcgta ctgccagctc aaacagcacc ttggcaagca
      781 tgggatagta ctcattggtc actgtgttgc tggctaagaa cgcgtggatt ccaaagcgct
      841 tcgctccctt ttcctttaaa atgcggaatg cctcaaacat ctgttctgtg gtcatgccgt
      901 acttggcgtc tcccggattg tccataatgt cgttgctgat tttaaacagt ccgcctggat
      961 tgtagcggca gctgatggtc tccggaatat ggcccactgc cttctccaga aattcaatat
     1021 gagtgatatc gtccaggtta atcactgctc ccaggcggtc tgccatctga aattcttccg
     1081 ccggggtatc gttggaggaa aacataatct tctttccatc gtatcccata gcctcagcca
     1141 tcatcagctc cgtcatggag gagcagtcca cgccgcagtc taacttcttt aaaatatcaa
     1201 tgataaaagg gttaggcgtt gcctttacgg caaaatactc gcgaaatccc ttattccagg
     1261 aaaacgctct ctttaagcgc tccgcattct ccctgattcc cttctcatcg tacagatgaa
     1321 acggtgtttt atatgtcttt gtaatctctt ttaactgttc cagtgttaca aacggtttct
     1381 tttccattct gtttctccct gtcttcccct gtctcttctc tctagtccac ctcggccacg
     1441 cgcataatgt tcgtgttggc tgccggtgaa tgccggttcg catatgtcac aacgccagct
     1501 gtggccacta ctacgtctcc tgtctttacg attcccttct cctttaacag ctcaatggag
     1561 gagtacacta aaacgtctgt ggaatctgcg cgtttggcgt ggaacggctt tacgccccag
     1621 taaagctgca tctggcgcac tgtggtcatg ctgggagaaa gtcccacgat ggtagcgctg
     1681 ggacgccatt ttgaaagcat cctggcagta aatccgctga cagacggagc cacgatagcc
     1741 gccgccccta aatcatgggc agtcgctaca gacgaataac acactgcatt ggaaatattc
     1801 ttctgattct cctggctgac tcttctctgg cggtaggaag cgtagtccag atacttttcc
     1861 gaatcctcca caatctgcgc catcattctg acagcctcca ccggatagcg gcccatggcg
     1921 gtctctcctg aaagcatcac tgcgtctgtt ccgtcataga cagcgttagc cacatccgtc
     1981 acctcggcgc gggtcggcct tgggttgcgg atcatggaat ccagcatctg agttgccgtg
     2041 ataaccggtt tgcatgcctt attgcatttt ttgatgatca gcttctggat atgaggaacc
     2101 ttctctgccg ggatttccac gcccatgtcg ccgcgggcca ccatgattcc gtcgcattcc
     2161 tccagaatgg aatccagatt ttcaattcct tctgcgttct caattttagc gataaccagc
     2221 attctggatc cgtgcttctc cagaatctcc ttaatttcac ggatcgcccc tgcattgcgc
     2281 acaaaggaag ccgcaatgta atcaaagcct gcctggattc caaacagaat atcctcttta
     2341 tccttgtccg tcagagccgg cagattaatt tttacgtttg gtacgttaac gccctttttt
     2401 tcacccagct ctccgccgtt ttttacccgg cagacaatat catttccttt tacctcctca
     2461 acgtccagct caatcaggcc gtcgtcgatg aggatctggt ttcctggctt tacgtctgcc
     2521 ggaagacctg cataattgat aaaacctctc gtatgatcgc ctaccgtctc ctcggtggtc
     2581 agcgtataga cgtctccctc tttcagagta accttctttc cgtcctttaa gcttcccgtt
     2641 cgaatctccg gtcccttcgt gtctaaaagc gccgcgatgg gaagccccag ttcctccctt
     2701 acgctctcga gaatcttaaa cctccccatg tgctcctcgt aatcaccgtg agagaaatta
     2761 aagcgggcca catccatgcc gtttaaagcc agctgcttca tcagctctct gtcattggta
     2821 ttcggaccca tggtgcagat aatttttgtt ttcttcatct tgttaattcc tcctgtattc
     2881 agccggaccc ccattgccgg cttcttcaac tggtttcccc ccgtttttcc tgtccccttc
     2941 tgcaaaacga ttattccaaa tcctcctttg tcacatgctt atgcgtatag aggtgatcca
     3001 tacagtattc caggtttccc tcgcacttgg aacaatagcg gaactccaga ttcggatcgt
     3061 ccttctctgt tcttccgcag acggcgcact tatggtgggt cagcctgatt ttttctgcct
     3121 gggccgtctt catatccgac ttgaatttct gttttctctt aatctccctg gggctgattt
     3181 tgctgtaatt tcttgtcatc ataaagaaaa tcacaaaatt cagcagagcc aggccgatac
     3241 agctcctggc aatcaggcct ccaaacagaa attcatacaa aaattctgcc ccaataaaaa
     3301 ttcccagcca gtacgcccgg ataggcagca gcccatacag atagaactgc atctgcggaa
     3361 acgtagccgc aaaagcgaga aacagcgagt tattcagata aaacggtgtc agcggcaccg
     3421 atacccccat taaaaagtag atcacgaaag ctgcgataat gtggaacaga atgcctgaga
     3481 aaaaatacag gttaaagcgg aaggttcccc atacccgttc cagcgtcgtt cccagcgaat
     3541 agtacaaaaa catggcgatc aggttaaaga aaatgcctga agacggcgga cagattaaaa
     3601 atgtgacaag tctccacacc tggcctctca aaatagcggc tgcgtccagg cagaggtact
     3661 gataatacag tccgggcatc accagatcaa tgacaattcc cgctccgtac atcaaaataa
     3721 tgtagtacat cagatttgga actgcgtatt ttccaaagtt cctttccagt tttcttaaaa
     3781 atttcatctc gtttcctgct ctctctttat gattcattgc tcgttaattc attattataa
     3841 atttagccga tgtctttgtc aaatgaattg tagccatctt atttcttcgt gcatttttaa
     3901 tgattttcga cgttttttta caggatttta acgcacctga tcaattgtat tctttcctat
     3961 tctatgttaa actatggccg aataaacctg tactacaaag gagggacggg gacttacccc
     4021 ggtttgatat atgaaatcct gtaagagact gggaatcgac atcggttcca caaccgtaaa
     4081 agttgcaatc attgacgaca gcggcagtat tctgttcgct gactacgagc gccactttgc
     4141 caatatccag gagacgctgg ccctgcttct taagcgggcc gtcgaggctc tgggggaaat
     4201 ggagctttat cctgtgatca ccggctccgg cggacttacg ctttcctccc gcctggaggt
     4261 tccgtttgtt caggaggtcg tagcagtcgc atcctcgctt caggactatg cgccgcagac
     4321 ggacgtggcc attgagctgg gcggagagga tgccaaaatt atctatttca cagggggaat
     4381 cgatcagcgc atgaacggca tctgcgcagg gggaaccggt tcctttatcg atcagatggc
     4441 gtctctgctg cagacggacg cctctggtct gaacgagtat gccaaaaatt acaaggcgat
     4501 ctacccgatt gccgcccgct gcggcgtatt tgccaaatca gacatccagc ctctgatcaa
     4561 tgagggcgct accagagaag atctggccgc ctccattttt caggcagttg tcaaccagac
     4621 gatcagcggc ctggcctgtg gaaagccgat ccgcggaaac gtggcttttc tgggaggtcc
     4681 tcttcacttc ctctccgagc ttcgggccgc ctttatcaga actctgaatc tggggccgga
     4741 tcagattatt gctccggatc actcccatct gttcgcagct gtaggcgcgg ccatgaactc
     4801 ccgccaggaa gtaaaaatgg acgcccaggc tctcatccgc cgtctgtctg agggaatcca
     4861 gatagacgct gaggtaaagc gcatggagcc gctgtttgaa aaccaggagg cctatgagaa
     4921 gttccaggcc cgccacgcca gccactgcgt caaaaagggc agccttaaag attataaggg
     4981 taactgcttt ctgggaattg acgccggttc caccaccacc aaggtggctc tggtaggcga
     5041 ggacggaacg ctgctctacc atttttacag caataacaac ggaagtcctc tggctaccgc
     5101 catccgggcc atgtcagaga ttcaaagcga gcttcctgag gaagcccaca ttgtctactc
     5161 ctgctccacc ggctatggag aagccctgtt aaaggccgct ttcatgctgg acgaggggga
     5221 agtggagact atctcccact actatgccgc agccttcttt gagccggatg tggactgcat
     5281 cctggacatc ggaggccagg atatgaagtg tatccgcatt aaggacggca cggtggacag
     5341 cgtgcagctg aacgaggcgt gctcctccgg ctgcggttcc tttatcgaga cctttgccaa
     5401 gtctctgaac tacagcgtca ttgacttcgc cagggaagcc ctgtttgcaa agactcccac
     5461 cgatctggga acgcgctgca cggtattcat gaactccaat gtgaagcagg cccagaagga
     5521 gggcgcgtct gtggctgata tctccgcagg cctggcttac tctgtcatca aaaacgcttt
     5581 atttaaggta attaaaatca caaacgcctc tgatctggga gagcatgtgg tcgttcaggg
     5641 cggaaccttc tacaacgacg cagtcctcag aagctttgag aaaatttccg gctgcgaggc
     5701 agtacgcccg gatatcgccg gcattatggg cgccttcgga gccgccctca tcgccaggga
     5761 gcggtacgac gcttcaaagg aaaccaccat gctccccatg gagaagattt taaatctgtc
     5821 ctataaaacc agcatgacaa gatgccaggg ctgcaccaac cactgcgtcc tgaccattaa
     5881 ccggtttgac ggagggcgtc agttcgtcac gggaaaccgc tgcgaacgcg gtcttggaca
     5941 cgccaaaaag aaggccgaca ttccaaacct gttcgattac aaataccacc ggatgtttga
     6001 ctacgagcct ctgaccgccg atgtggcgga gcggggaacc gtaggaattc ccagggtgtt
     6061 aaacctgtat gaaaattatc cgttctgggc tgtatttttt aaagagctgg gatttcggac
     6121 gattctctcc ccccagtcta ccagaaagct ctacgagctg ggcattgaat ccattcccag
     6181 cgaatcggag tgctatccgg ccaagctggc ccatggccat gtagagtggc tgattaaaca
     6241 gggcgtaacg tacatattct atccgtgcat tccttatgag cgaaacgaga cgcctgaggc
     6301 aggaaaccat tacaactgtc ctatggttac ctcctatgcg gaaaacatca agaacaatgt
     6361 ggaggagctt cacggcgata agattctgtt ccgcaatccg tttatggcct tcacaaacaa
     6421 ggaggttctc tccgaagctc ttgtgaagga atttacggaa cagttccaga ttccggagca
     6481 ggaaattctg gacgccgccg ataaggcctg ggcggagctg attgcttcca gagaggatat
     6541 gaagagaaag ggcgaggaga ctctgcagtg gttaaagaaa aacaaccgcc gcggcatcgt
     6601 tctggccgga cgtccctacc atgtggatcc ggagatcaac cacggcattc cggagctgat
     6661 cgcctcctac ggctttgccg ttctgacaga ggattccgtg tcccatctag gccatgtgga
     6721 gcggccgctg attgtcacag accagtggat gtaccactcc cgcctctacg ccgccgccaa
     6781 tttcgtaaag acgcagaaaa acctggattt aattcagctg aattcctttg gctgcgggct
     6841 ggacgccgtg actacagatc aggtaaacga tattctcacc cgttccggca aaatttacac
     6901 ctgcttaaag atcgacgagg tcaataacct gggagcggcc agaatcagaa tccgttccct
     6961 gatttcagcc atccgcgtcc gtgaaatgaa gcactatgac aagcctgcgg tatcaagcgc
     7021 ttataaccgc gttctcttta caaaagagat gaaaaaggac tacaccatct tatgtccgca
     7081 gatgtccccc atccactttg atctggtgga ggcggccatt cgaagctgcg gctaccggct
     7141 ggaggtactg cagaattcag acagaaccgc tgtggacact ggattaaagt acgtcaataa
     7201 cgacgcctgc tatccgtccc tgattgtggt aggacagatt atggacgccc tgctttcagg
     7261 aaagtacgat ttaaaccgca cggctgttat tatgtcccag acaggagggg gctgccgcgc
     7321 ttccaactac atcggtttta tcagacgcgc tctggagaag gccggaatgc cgcagattcc
     7381 cgttatctcc ctgaatgcca acggcatgga gaccaatcca ggcttttcct tcactcttcc
     7441 catggtgatc aaagctttac aggcagttgt gtacggcgat atctttatgc gggtgctcta
     7501 cgccacccgt ccctacgagg ccaaacctgg aagcgccaac gctcttcacc agaagtggaa
     7561 ggagacgtgc atccagtccc tgagccggaa aaagccgtcc atgaaggagt tcggaaacaa
     7621 tctcagagcc attatctctg aatttgacgc tcttcccaga aaaaatgtgg tgaagccgaa
     7681 ggtgggaatc gtaggagaaa ttctggtaaa attctcgccc ctggccaaca atcatgtggt
     7741 agatctgctg gaaagcgagg gagctgaggc agttatgccg gatctcttag acttcctcct
     7801 ctactgtttc tacaactcga attttaaggc tgaaaatctg ggaggaaaga aatcgaccgc
     7861 ctggctctgc aacgcggcca tccagcttct ggaatacttc cggcgcacag ccagaaaaga
     7921 gctggaaaag agcgtccact ttacgcctcc tgcccgcatc cacgatctgg ccgccatggc
     7981 caaatcctat gtgtccctgg gcaatcagac cggagagggc tggttcttaa ccggcgagat
     8041 gctggagctg attcacagcg gcacaaacaa cattatctgc actcagccat tcggctgcct
     8101 gccgaaccat attgtaggca agggcgtgat caaagagctg agagcttccc atccagaggc
     8161 aaatatcatt gccgtggact atgatccagg agccagtgaa gtcaatcagc tgaaccgaat
     8221 caagctgatg ctggctaccg cccagaaaaa tctggaacgc gaatgtgcag aggaggccgc
     8281 cgtttccagg gaaatggcgt aagcagctgt ccttctgttt atgaatattt tgtgaatatt
     8341 tgattacaat ttttttaatg acaaatattc cttcctgtga tagaataaaa acagatagga
     8401 ggttcttact atgggtttga aaacatttgc ctgcgctctt gcgctgactc tttcttatac
     8461 agttacagcc tttggagctg aaccgcagac tgctttgcag acgctctctt ccgatgttgt
     8521 gaaggcagct tccaatgaag cgattcctat gaccggttct aaaattgtca ctgatgattt
     8581 ttcttttgtg gttccagagc gctggactgg gaaatgtgtc gtactcccca cagaacaggg
     8641 cctggaagtg tacgatcagg aggattatga gagcgacgga tccggctttc tgttttccat
     8701 ctccgtttac gaggacgaca gctactcttc tctggaggat tacgccattc tcggattctg
     8761 cggaagtgaa acctttgtgt tagatacctc gaaagctgac gagagcaaaa gcgtcaaaaa
     8821 ggggctgaag gagcttcagg aaacctttgt cgcctttgcc ggaaatgaaa attagatttg
     8881 attttctatg aatattcaaa aaccacactg caggagtttt ttgcagtgtg gtttttgttt
     8941 tgcagttttg ccgcgcgcct tctctcagac gccttttatt tcccattgat aagccgcaat
     9001 cgtctggctc aactcccgtt cagcctgctt gaaggaattt ttctgctgga gataggaaac
     9061 ttcccctttg agatactcct gccttgagag aaggccagac tgatatttaa cctgaagagc
     9121 gccgtaattt ttctctgccg cttcataact gctttctgct gcctgaaaag cctgtagttt
     9181 cgcagtcatc tcattgtaaa gcgtatccat ttccaggttc ttccggcttt tcgcctctga
     9241 tatttggcgg gatttcagct ctgcttcagc gctgccgcct gacgaagagc ctcttctgag
     9301 ggcctgaatc tctgaatcac tgatcactgc cagctttttg tcgtcctcca gaacaactgt
     9361 gtcaataaaa tccacattgg ccggcggaat ctctccaatc tctgtatcgt ctggattcct
     9421 ccctattaag agagacagct gcgccttcat ggatgcttcg cttttttctg ctgactgaag
     9481 ggaaatccgg gctgtcagaa gactctgctc tgcttccagg agctcctgct ctgtaagcat
     9541 tcctgcttct gccatcgtct gtgccttttc ataggaagct ctggcgcttt cctcctgttt
     9601 ttctgccaat tgcctctgat ccctcatctg gttatagctg cacatcacag tctgggctgt
     9661 ctttaccatg gcattgacgg aagatttcag gaatttcgtc ccgctcaccc ctgtcagttt
     9721 cctgacggtg cggttcatct gcgccacaga ggcccccagc tggctttcat tcatctggta
     9781 ctgggcaatc agttccgggc ttccattttc attctccagt tcctctgcgt attccttcat
     9841 ctcctgcttt gcggatgaga ggacctctaa tgcctcctga taaatttcca gattggtgtc
     9901 atactggctg actgccgatt tcagggaagc atttccgcgt ttcagcagtt cctccagctc
     9961 cccgtactct atcagggagt ctgtcagttc ctcctctgta aaggaatccg tctccccgtc
    10021 ttctgtttcc ttttcttctc cattttcccc cagtcccggt ccctccagct ctgcctcgtc
    10081 cccctccccg gagcgcagca gctctgtctc tgtcacctcc ggagacctgg ccgcctgggc
    10141 gggaaaggag gcagacagtg tcaggaaaag cagactgcct gtcagccatt tgtttcgtat
    10201 tttttgcttt ttcttcaatg aaacattcct cctcgctttt tcaaaaacat caggatactg
    10261 ctgccagtcc tgccactgcc cagtcgtatt ccagtttggc agaaagaagc tggaaagagg
    10321 ctgtctgttt cgacgattcc gccgtctcgc aggcgcttac ggctgacgcc aggctgttgg
    10381 cgctcagaag cccggcctcc tgttttctcc tcgctgtttc cagggactgc tctttcagat
    10441 acttcgcctt gacagcctgt tcatactgat tttctgcgag aagaagattc tgataagcca
    10501 ttgtcacatt cgcccggacg gcctgacgcc cgcttgtcag cgtttccctg accgatgctt
    10561 ctgttgtgct ggaatgtgcg ttctgcagct gcctgcccaa aattttcaag tcgtaattat
    10621 tctccagtgc ctgttcgata tcggtctcca ggctgatgcc cgctatggca gcaggatccg
    10681 gctccggaag gcttcctatt tctactgaat ctccctcatt ccatcccagc ataaggatga
    10741 ggctggtttt tgtctccttc aggctgctct gttcagaagt gatttctgat ttcagattca
    10801 gcaccgtctg ctctgccgtc aatacctcag actggacagc catgcctgcg gcaagctttc
    10861 tctttactga ttcctcgctg ttttccgctt ccagaagctc ctgttctaag gatgacagct
    10921 tctccacact gctccagtag gaaatcatca gagactgtgc ctgtctgacc agcttttttt
    10981 ccgcctggat atagctccat ttcacagtat cctcatcctc cacgctggcg tctcctgatt
    11041 ccttcaggct ttccgctctc tgctcattat tgatatagga agccagagcc gacgcatagg
    11101 aagaagaatc tggatccaga tccggctggc tgtcgtaaat ctcctccgcc gcgtcatagt
    11161 attcctgcgc aatttcactg ctgtcttttc cctgataatc cttatagctg atttcattct
    11221 gccttaccgt ggtattgtat tcatggatcc gcttgtcaat ttcttcaaac tccagcttat
    11281 tgtcacggat tgcagcccac tcttcctccg tataggcaaa cggaggactg gccgcccagg
    11341 cctgaagcgg aaagcagagc tggaagaccg ctgtcatgcc tgctgccaga gctgtttttt
    11401 gtacccacca ttttttcatt gtcctttcac ctcttctgct tttaatctat atcccagtcc
    11461 tcatttatct ttcttggctt ccggttcatc agcccgtagt acaccggcag catgaaaaga
    11521 gccacaaaca ggcctgctgt caggccgcca atatctacaa tcgccaggcc ctgggttgtg
    11581 gaaccgctgc ttcccatggc ggcagccatt ggaagcatgc caagaatggt cgtaaggctg
    11641 gtcatcagca tcggtctcag acggacagca cctgcttcta tcatagcagt ttccaggtcc
    11701 atttccatcc ggtactgatt cactgtgtct acatagagaa ttccattgtt gacaactgtt
    11761 cccaccagaa tcaggaatcc gagaatggac gtcatgctca tggatacccc tgtcagcttc
    11821 agaaatccaa atgagccgat cagactgaag ggaatggttg tcataaccat aacagaaaac
    11881 ttcactgact caaactgggc tgccataacg acaaaaatca gaaataccgc cacggcaatg
    11941 gcctggtaca gggaggaaaa ctcttcgttc atcatacggt ccatactgct cgttcccttt
    12001 ttgatggttc cagtcagatt aggggcaatc acctcgcttt cgatctgggc tgaggtatcc
    12061 gcacctgtgt attctccggt aatagttact ttgaaggatt gatcctccct gctgatggac
    12121 gacggactgt ccttatacac aatatctgct acatcggtca gggctgtggc cgttccgtct
    12181 cctgccgtca ggattatatt tttcatctga tcaatggacg catactctcc ttccggaaac
    12241 tccaccttta cgtcaagatc ctctccgtcc acggtcagcg ccgccgctgt cattccgctg
    12301 agcgtctgat tcacggcaga gccgatggaa gaagccgtca gcccctttct gctggccata
    12361 agaggatcca cgtcaatgga tacaatggga gcattatttt caaaagaaga atgaatgttg
    12421 atcacgtcat cacggctgat gagctctgac acaatcttat cgctcagttc cttcagctct
    12481 ccgtaatccg ttcctgtcag aatcgtctca tatccccgcg ttctctgcat aaaactcatg
    12541 gaactgccgg ctgtaacctc tgtgctgaca ttttcaatgt ctgacagctc ctgctgccac
    12601 tgttctgcca gctgtgccgt atcctctgtc ctgtcgtcct tcagataagc tgtaactgaa
    12661 ccgctctggt tctggtaccg gagcatataa gaatctacat tttcattaga agatactatc
    12721 tcctcaatcc gggccagagc gtcttctgtc ttctcctcaa tcagtcccgg acgcgtctct
    12781 atctctatct taatctggcc tgtatcgtct gaggtgatca gctcgcttct cattccggat
    12841 gccaggcaga aggtcgctgc cagcatagcg gctgagacag ccattaccct ccccttatgg
    12901 cgaagcagct ttttcatgac ttttctgtag aagttctgaa ggcgttccac tggccctgac
    12961 ataaaggagc ttgacttctc ctggggctta tacataacgt agcagagagg aactactgta
    13021 attgccgaca gcagagaagc caccatacag aacacaaccg tataccccag aggaccaaac
    13081 atctgccccg acatgccctg aactgccgcc agggggagaa atactacgca ggtagtggca
    13141 gtacctccga taatggaggc cagcacctga ttgcttccca gcagggccgc cttggcgtat
    13201 ccaaaaatcc ccttatccct gtttaactct gctgcccgga aacagctttc cagaactacg
    13261 atggagttat ccaccatcat tcccactccc agaaccaggg cgctcatggt aatgacattc
    13321 agcgaagagc ctgccgcggt tatggcaatc agagacagca gaatcgacgt ggggatggag
    13381 cttcctacaa tcagagaagc ttttaaatct ccaaaaaaca ggaaaatgat gatcatggag
    13441 ataataaccg acagtaccat ggtctctgcc acatccttca gcgactccaa aatcgtgtct
    13501 gccgtatcat ttaccacctc tgctgtcaga tccggatcag cgtcctggag ttcttgtatc
    13561 gtctccctga cagccctgga aacctcaata tctgtattgc tctgattttt cataacagag
    13621 atagaaatcg tctccgcccc gtcataccgg gaaatgcctc ctcttttctc ctctttcgtg
    13681 tgaacatccg ccacatcctg caagcggaca atctccccgg tggacgcagt gacaggaaca
    13741 ttctttaact cctctatatc cgacgtttcc agggaggtgg tgacagacag ctccagattc
    13801 ccggaaaccg tatcgccgga aggaagggag acgttggcat tctgaattgc cgaagaaatc
    13861 tgggacatgg tcactttata ctgatccatc ttttcccggt tcagctccac ctggatatat
    13921 tctgaggttc ctcccatggc ctccacagaa gctacagaag caattttttc aagctcaggc
    13981 acaatcttct gttccgcata gctgtacaga tccgtctccg ttttatggct gatggacagc
    14041 atcatggacg tccctgcatt ctggcccatt tccatgactg tcggcgtgtc catgtcctcc
    14101 ggaagctggc gttccaggct gctcattttt ttagtcagct cattatacgc ctcatccatg
    14161 tcagttccat aatcatactc cagcataatc ctggcagaac cgtcgctgga ggaggaactg
    14221 atgcttttta caccctccag ggtgctgacg gcatcctcta tgggttctgt taccaactcg
    14281 ctgatatcct ccggtccggc tccctcgtag cgcgccataa tcgtcatcat cggcgtttcc
    14341 atctccggca tctgctctaa cgaagcgtga aataccgatg agatgccaaa taccagcaga
    14401 cacagaagcg tcataataac agtcaccgga cgtttcagaa caaatttcgt aattcccatg
    14461 atcttcctcc tctgctatgg ttccggcatc ggatccagcg gctcccctgc attttctttt
    14521 tgctgcctgt ctggctgttc gcctgttttc tcatttttaa gctttactgt gcttccctca
    14581 tagagctctg agctccaggt gctgattacc agatctgact ccgtcagccc cgactgaatt
    14641 tcagccagat ttgaatcaaa aattcccacc tccacttcct gtttgtgaac ttttccatcc
    14701 tggtaaagat agacgtttcc cactccgccg tcaaaataaa cagcatccac cggaactgtc
    14761 atcacattct ccgctctgtc agaaacaaga taaatcttca ccacacttcc caacgccaca
    14821 gagtccgctc catttatgct tcccttcact tcaaacaggc ctgtggaggc gtctgccata
    14881 ccgctcacct ctgtaatcga gccgctgtag gtttctccat ccctctccac tctcaattcg
    14941 ccgccggcag acagatgcct ggccactctc tctgtcacct tgaatttcag tgtctgggct
    15001 ccttctcctg aaatcacaca cagctcttca ttggccgaca catggtcaaa tgcttcgata
    15061 ctgcagcttt ctattacccc tgaaacaggc gccgtaatat tgctgtactc catctggttt
    15121 tcgtaggaca ttttggcaga ctcataggaa aggcgcgcag actcggcctg attctgatat
    15181 tgttcatatt cctgatctga aatatcgcct cctgcataca aaagctcctg gcggctcagc
    15241 gtgctctgag cagactcgta ggaaagtctg gcggattcca tggcattttc agcggcttcc
    15301 acctgctttg tatcgatcac agctaacagc tgccccgcct ccacggtatc gccggcctta
    15361 accagaacag aggttacgtc tcccgccgct cttgcataaa ggtaaaccac atctgacggc
    15421 tctacggttc ctgttacagc tgtctccagt tcaatgcttc ctgtgcccgg aggctccgct
    15481 gatacagccg tcacgttcat ctgacgatcc atgtctgccg gccttccttc cggtctcttc
    15541 cctcctcttc ctgatgcgaa ggcagccgcc gctataaaaa tcagcgctgc cggaatcact
    15601 atttttttct tcttcatcag gcgatctgac gtccgaagca gccattcccg attcaggttc
    15661 tttttatcca taacgcttct cctctcatat attctgaaaa gcagtatacc atttctcctt
    15721 aaattgaatt taaaccctct ttaaactgaa tataaactaa tcttgaaact tttgtgtctc
    15781 tgtttatgga aagttaacat tcctgtgcta tactgttctc atcagaagga aaatagctgc
    15841 cctgcaaggc ggcaaagaga ggtgaaactg atgttcaata ttcttgtagt tgaagatgac
    15901 aggaaactga gaaatctgtt ctgtaccgtt ctgtcccaca gcggatactg tgccataccg
    15961 gcagaaaacg gcatgtccgc tctcggaatc ctggatacag aatatatcga tctggttatt
    16021 tctgatatta tgatgcctgg aatggatgga tatgagctga ttgaaacctt aagagaacac
    16081 ggatatacga tgccgattct gattatcact gccaaggctc agtttgagga caagcagaga
    16141 ggtttctggg caggaactga cgactatatg gtaaaaccca ttgatgtcaa tgaaatggta
    16201 ctccgtgtag gcgcgcttct aaagagagcc cgcatttcca ctgaacggaa aattgtctgc
    16261 ggcaatacgg ttctggacta tgacgccctg acagtccgct gcggcagaga agtctccctg
    16321 cttccccaga aggaattcta tctgctctat aagctgatgg cctatcccaa taaaatcttc
    16381 accagaagac agctgatgga tgaaatctgg gggatggact cttcctccga ggaacggact
    16441 gtggacgtcc atattaaccg gctgagggag cgttttaagg actgcacgga ttttcagatt
    16501 cagaccgtgc ggggactggg atacaaggtg gtgaagcagg agtcatgaaa cgtcatatat
    16561 ctcccattaa attttatatt attttgatta tcctggcctg cactacagtt acccctacat
    16621 tggccggatg gcttcttttt cacttttccg actggaaata cggtccgaat ccctattttc
    16681 cgctgatgaa tacgctgatt gaaagcctgc ttgcaggaat ttttctgact ctgatgatta
    16741 accattttct gctgtctccg attatgtctt ttatagacgc tatcaaccag gtttcaaaag
    16801 gcgatttttc tgtccgggta aaaactgatt attcctctcc ggaactggat gaattagccg
    16861 gccattttaa taaaatggta caggagcttg gaagcatcga ggctcttcgg aatgattttg
    16921 ccgccaatat cagccatgaa ttccgcactc ctctggctgc cattgaaggg tatacaactc
    16981 tgctgcagga tcacagcctg tccgatcagg agcgggatga atatacacac attatcattg
    17041 acagcgtccg ccagctgtcc agcctgtccg aaaatattct ttctatgtcc agactggaaa
    17101 agcaggagat tgtcaccaac aaaaccacct actcgctgga cgagcagatc cgccaggctg
    17161 tgctcctctt agagcccctg tggagcgaaa aaaagatgga actggacatc gacctggaat
    17221 cagccctcta ttacggcaac tgcgacatga tgatgcaggt ctggctgaat cttcttcata
    17281 atgctatcca gtacactccg gcagaaggca caatctctgt ttttctaaag aaaacaaagc
    17341 acagtctcct gattacagtt gcagatacag gcatcggcat ggacgaggct actctgtccc
    17401 atattttcga taaatttttc cggaaagata aggactcctc tcccggaaac ggcctgggat
    17461 tgcctatggt gaaacggatc ctccagctga atcagggctc tgtcacagtt gaaagtacgc
    17521 ctggcagcgg atcctccttt gtggtgacgc tccctgtgca gaaatagagc agcttttcat
    17581 taaaaaagac ggatctgact ctctgtaaga atcaaatccg tcttcttttt tcatattata
    17641 tatctgtcta tttgccgctt cccgtttttc cgcttccagc ataggaaacg tacatctgcg
    17701 tagtcgccat atcggagtgt cctaaaatct gctgcactgc cttgatatca gctccgctgc
    17761 tgataagatg agccgcaaag gaatggcgga gtgtgtgggg cgtaatgtct gcctgaattc
    17821 ctgccttctc cccgtagtat tttaaaattt tccagaatcc ctgtctgctc atgcggcctc
    17881 cgctgcagtt gacgaacagc cactccgact ccttctgttt taaaagctcc ggtctggagt
    17941 gcttcatata atcgtcaaga gccttcttcg ccacacggcc aaagggaatg gttctctccc
    18001 ggccgctgtc gctgcaggtg ataaatccaa tggtcatatt cacatgggac aggcttagat
    18061 tcatcagctc tgacacacgg attcctgtgg catagagaag ctccagcatc gctttatcac
    18121 gaatctcctt cggagtcctg ccggacggct gagccaacag gcgggtcacc tcttctaccg
    18181 ttaaaatcgc cggagccttt ttttcaattt taggcgccct cactaaatct gccggatttc
    18241 tcctgatccg tccttccgaa aattcatagt gaaaaaatgc cttgattgag gccagcatac
    18301 gcgaaatagt ggcaggggcc tttctctctt tttccagaaa aaggatatag gaatccagac
    18361 tggtcttcgt caccttccca gcctctctca ctcccctatc ttccatataa gatgcaaact
    18421 gcagtaaatc gcgtctgtac gagagaatcg tattctgcga catccgtttt acgtcctgga
    18481 gatataccgc aaatctctct atctcatcaa acatacttcg tcccctaatc gttctgtatt
    18541 gctgtaaaaa caaggcaaaa tccgcttgta actaccatta tatctacatt ttccccataa
    18601 atcaaacaca tttttcccac ttttccgcag cctttcatag gattgacaaa aaatacacaa
    18661 gatatggttt tatcgtcctt atcaacgcaa gatattgaat ttttttccgc tttttttagt
    18721 aaaaaaagat tgctcctatc catgatatcc atctgggatt cagccatacc tctgcggcgg
    18781 atcctgccgc cagaactgcc aaaagaatca ggaatgccgc cgcccggacc tttttttctt
    18841 ctttcaggcc ccatcgaacc aaaacggctg ctgcaggcgc ataaaaaaga cattggggaa
    18901 acaatgccag gagaaacagt ggaagagcaa gaaagcctgt ctcagcagtg agcgcagaaa
    18961 gcactgcggc catagaaaat ccgacagccg atgacgccag acataggact gccaggctgc
    19021 agggcgtcat tcctgccagc caaaccacag ccgccagacc agccctcctc acaaatacag
    19081 aatagaaggc tccctcctct gctctgagcc tgcattgggg ccggctcgtc catacgcgcc
    19141 ctaatattcc cagcgtttcc tgtatgtttt ccggcagacg gttaaaccac agactggccg
    19201 ccatggcaga taaaaacaga cagaaaagca gcggcataag aggtttcctt cggaacgctc
    19261 caagaactga tttcatcatc ctgttccgct ttcctttttt tcatcttatg ccgctgtctt
    19321 tcattccaga cgcgctattt ttctatttct gacatccata tttgaccgcg taagcaagaa
    19381 tggaagccgc agtcttaccg tctgtaatag tcccggaata aatcagcttc agcagatcct
    19441 ccagttccca ttcctccacc tgaatatttt catctggatc caggtgctgc ttagacggaa
    19501 tcaggttcct ggccacaaac acatcgattg cctcatcgca gaaagcaatg gttgtgttaa
    19561 tgcttaagag atattccaga tgctctgttt taaatccagt ctcttcctcc agctctctgt
    19621 atgcgcactc aatcttcggc tcttccgggt agtccagcgc tcctgccgga atttccagag
    19681 tgtagcgatc cagcgcgttt ctgtactggc gcaccatcaa aagctttccc tcttttgtca
    19741 cagccaccac agccgccgca ccgttgtggt ggatatagtc ccactttgcc tcatggccgt
    19801 taacctgaac cgtgtcctgg tataccttca gaatggctcc ctgatacttt aattcccggt
    19861 tgactctctt tacaggaatg tctgccagat tctttgctgc ttctgcctct tctgctgttc
    19921 ttttattttt ctccatagaa ttttccttct ttctccttcc tgctgccttt ttttgttatt
    19981 tcatattcag acatttctca tagcaggcgt cggccgcttt tatcactgcg ctgcggaaac
    20041 catgctcttc cagagccgat acggctgcaa tcgtagtgcc gcctggagaa catacccgat
    20101 ccttcagcgt tcctggatgt tcccccgttt caagaaccat tttagcgctt cccatcactg
    20161 cctgagctgc catacgatat gccgtatctc tgggaagacc gtattttacc gcgctgtccg
    20221 ccagcgcttc gataaacata taaacgtatg caggagaact tccgctggca cagacgactg
    20281 cgttaatcag cctttcctct accagctcca tggttccgaa ggattcaaaa aatgtgcgga
    20341 tcaccgcttc ctcctcctgg gtgaattcct tcctgtcata gcagactcca gtcactccca
    20401 ttcccaccag ggccggcgta ttcggcatcg ctctgacaat tctcttatcc tgccccagag
    20461 ctgcttttaa atctgcaatc gttacagatg gagcgattga aataatgatc tgttcctttt
    20521 taataatatc cttcacatca tcgagaacca tgtgataaaa ctgcggtttt actgccagaa
    20581 ctacaaactc tgcctgagag gcacatgact gattatctcc tgccgcctca acccctgtct
    20641 cccgggaaac tgcctctgcc cgttcctgat ttgcatccgt caaaatcagt tctgtcttat
    20701 caaacacctg cagcagtcct tttaaaatgg catatcccat atttcccatt ccaataaaac
    20761 caattttttt cattctgcgt tctcctccat ctgtcttctt ctcttctttg tttcctttga
    20821 aggctggttt cattttaaac ctgtggtttt tctctgtcaa gaacagcgtc agaaaagccg
    20881 aagagggaag cctgccttac cggtactacc gataaggcag gcttccctct ttgccttcat
    20941 ttcgctggct gtgatgctca gaacatgttt gttcccttta tttacttcgc ataatccgtc
    21001 actctggact cgcgaattac attcaccttg atctggccag gatattccag ttctgcctcg
    21061 attctcttgg aaatttccct tgccatcagt accattccat cgtcgtttac ctgttccggt
    21121 acaaccatga ttcgtacttc ccggcctgcc tggattgcaa aagacttatc gactccctta
    21181 aaggagtttg tgatatcctc cagctgtctc agacggtttg tatatgtttc cagagtttcc
    21241 cgccttgctc caggtcttgc ggctgaaatc gtatcagctg cctgaaccag acaggcaatc
    21301 aggctctgcg gctccacatc gccatgatgg gattccactg cgttaatgac aatggctgat
    21361 tccttatact ttctgcacag atccactcca agcttcacat gtgtgccttc catctcatgg
    21421 tcaacagcct tgccaatatc atgtaataaa ccggctcttt ttgccgtgcg gacgtcgact
    21481 ccgacctctg cggctaacag tccggcaagc tgcgctacct caattgaatg ctttaaggca
    21541 ttctgtccgt agcttgtcct gaatttcatc tttccaagga gcttcactaa ctctgggtgg
    21601 attccatgaa ttccaacctc cagaagagct gcctctccct cttcgcgcat catggtttca
    21661 acttccttct gcgccttttc taccatttcc tcgattctcg ccggatggat tcgtccgtct
    21721 acaatcagac gctccaaagc gattctggca acctctcttc gaatcggatc aaagccagaa
    21781 agaacgactg cctccggtgt atcgtcgata atcagctcta cgccggttaa agtctccagg
    21841 gttctgatgt ttcttccttc tcgtccgatg attctgccct tcatctcatc attgggaagc
    21901 tgtaccaccg atacagtagt ctctgccaca tgatctgccg cacagcgctg aatcgcggtg
    21961 actacgtagt ctttagcctt cttatcggcc tcttccttcg cttttgcctc catctcctta
    22021 atcagctttg cggtatcatg ctttacatct tcctcaacgg attttaacag gtattccttc
    22081 gcctgctctg atgtaaggcc ggaaatcttt tccagctcct gcatcccttt ctcgtaaagc
    22141 tcttccacct ctgtggttct ctttttcaga gcgtcctcgc gggtattcaa tcctgcctca
    22201 cgcttttcaa tggcctctga cttcttgtcc agattctctt ccttgctcag cacacgtcgt
    22261 tcatagcgct gaagctctgc tcttctttcc tttgtttctt tctcaagctc attctttgtc
    22321 ttcagtgact cttccttcgc ttcaaggaga gcttctcgct tctttgtctc tgcaaccttt
    22381 aatgcttcat ctattatttc ccttgatcgt tcttctgcac tgccaatctt tgcctcataa
    22441 gttttcttct gatgattaac agcgacgaac caagtaataa cagcaacaat aaccgccgta
    22501 acaacgcaca taattattac ttgtggcaca ggagcacctc cttatttagt tttcattgta
    22561 catatcaata caacactaca attttaaact gttttataca ctatgtcaag tataatagga
    22621 agtgtttcct ctttttcgtc actatctaac aaacgtctca gagagaactc tccgcacagt
    22681 atcataggaa aatcccttcc tcatcagata ggccgtctgc ctggctgtct ccttctgatc
    22741 cgcctcctcc ggatgaaatc tccgtttctc gagaatccgg cggatctgcg cttcttcatc
    22801 caccggattc tcctccatca gcctgcttac gcactctctg ctgatgcctt tccggcttaa
    22861 cagagcggcc agctctgcgc ggctttttcc gctggcatga acctctataa aatttctggc
    22921 atactcctca tcgtcgatat atcggtactg cttcagcaga tcaatcacat aatcgacagc
    22981 tgccggagga tagctgttat cccgcagctt cctccgcagc tcctcctcgg tcctggccga
    23041 acacttgagc caatagactg cccgctctct ggcgcgcttg aatatgattt cacggagaat
    23101 tttctgatac agctcctctg ccagctcccc gccttcctcc agccccagct gtcttatctc
    23161 gcccaagtaa agagcaaatg cgaattctcc atcagcaaat attttctttc ttctcctgtc
    23221 cagagtctca atcctgtcga taatcatgct tactcttctg aatcaaattc aggcatagca
    23281 agcttcgccg catctgcctt ctctgcgccc ttctcctcct cggaagctcc gtccaggctg
    23341 tacttagccc gaaccttagc ctctatctcc tggcacatct cctgatttgc ctgaaggaat
    23401 cccttggcat tctcacgtcc ctgtccgatc ttgcttccat tataagcgta ccaggcaccg
    23461 ctcttctcca caatattctc cttcacggcc agatccagga tatctccctc ctttgagatg
    23521 ccctttccga acataatatc gaactctgcc tccttaaacg gcggagcaat cttgtttttc
    23581 acaaccttaa tacggacgcg gtttccaacc atctcgccgc cctgctttaa agtctcgatt
    23641 ctcctgacat ccatgcggac agaagaatag aacttcagcg cgcgtcctcc tgtagtcgtc
    23701 tctggatttc cgaacatcac gcctaccttc tcacgaagct ggttaataaa aataacaata
    23761 cagttggact tgctgataat cgcagtcagc tttctcagag cctgagacat cagacgggcc
    23821 tgaagtccca catgggaatc tcccatctca ccgtcaatct ctgccttagg caccagagcc
    23881 gccacagagt ccacaatcac aatgtcaaca gcgccggaac gtaccatggt ctccgtaatt
    23941 tcaagagcct gctctccatt atccggctgg gaaatgtaaa gattatcaat atccacaccg
    24001 atatttttcg cataaacagg atccagagcg tgctccgcgt cgataaatcc cgcaatgccg
    24061 cctctcttct ggacttccgc taccatatgc agggcaacgg tcgtcttacc gctggactca
    24121 ggtccgtata cctcgataat acggcctctc ggcacgccgc ccagtcccag ggcaatgtca
    24181 agactcagag agccggtcgg aactgtctca atgttcatat tcgcgctgga atctcccagc
    24241 ttcatcacgg atcccttacc gtatgccttc tcgatctgtg tcaatgcggc gtcaagcgcc
    24301 ttcagcttct cttccctatc cataatatcc tccatctctg ctgttttatc ctgattttca
    24361 gcatcctgct ctgcttctca aatataaagt caaacgtcct tctcgtcatc agtttctcaa
    24421 aaatagaaca agtgttctgt ttatgtaact atcatagtat agccgttctc aaatgtcaac
    24481 tgttattttg tttttattct gtaaaatcct caaaatgaaa tagctgccga aacggcggaa
    24541 ggtaaactct gagcctgtaa aacaggacgg aaaataaaga attgtttcgt gttcttagtg
    24601 taccacattc cccgttttct gtccagccgg atcctctcgc ttttttccta tgtttttcct
    24661 tctttcagag cttccgccct tctgcctctt tgacatttct ccctccccgt tgacattccg
    24721 tcctgttcta tatataatcg ttatattata cggtacaaag gagtttttac aatgttaagc
    24781 aatcgtgttt gggcattgac tcccgccaaa attattttag gcggattctt tctgattatc
    24841 acggctggag cccttctcct gactctgcct atctcgtcaa aaagcggaga gatgactcct
    24901 tttattgacg cgttttttac agcgacctca gctacctgcg tgacaggtct ggtggtccat
    24961 gatacctata cctactggtc tgtgttcggc cagtctgtca tccttcttct gattcagata
    25021 ggaggaatgg gcgtcgttac tctggccatt gccatcacga ttctttcagg aagaaaaatc
    25081 ggtttaaagc agcgctttgt catgcaggaa tccatctcag ccccccaggt aggcggcatt
    25141 gtccgtatga cgaactttat tattaaaggc acgctgctgc tggagctgat cggcgcattt
    25201 attatggcag ttcagttctg cccgcagttt ggagtgataa agggaatctg gttttccatt
    25261 tttcactcta tttcagcttt ctgcaatgca ggtttcgacc tgatgggcgg cacttccggc
    25321 ctttattcct ccctgaccag ctaccattcc aatcctctga ttgtcgttcc ggttatgctt
    25381 ctgattgtag taggaggaat cggctttttt gtatgggacg atattatcca gcacagagag
    25441 acgcgcagag cgttccgtct tcagacaaag gtagttctca cctacacctt ttttctgatt
    25501 ctgatcccgg cagttctctt tttcctgttc gagtttacgc ctcagcggtg ggaagggtat
    25561 tcgctggctg atcggctcta cgcgtccttc tttcagtcgg ttacgcccag aacagccggt
    25621 tttaatacag ttcccctgga cgggctttcc acccaggccc agcttttgac catcatgctg
    25681 atgattatcg gaggatcccc cggttctacg gcaggaggca ttaagacgac cacctttgcg
    25741 gtggcgcttt tgtgtatccg ctctgtcttc caaaatcagg aggggatcca ctgctataag
    25801 aggcgaatcc cctacgagat tctgagaaac gccattgcca ttctggttct gtatctgagc
    25861 ctgtttctgg cagccagttt tctcattacc tgggcggatg gagtaacgct gatggagtct
    25921 tcctttgaag cggcctccgc cattgccaca gtaggccttt ctctgggtat tacggaggat
    25981 ttgagcctct tttcaaaaat gattctgatt cttttaatgt attttggacg agttggcgga
    26041 cttaccatgc tgtatgccct cacaaaccat aaaaaattcc ccttccacct gcctgaggag
    26101 aagatcacgg taggttaagc tggaagaggc agacggaggt gttttatgaa atcaattctt
    26161 ttgatcggac tgggacgttt cggcgctact atggctatga agcttcacga gctgaagcat
    26221 gaggtcatgg cgattgatat ttcggaggag cgtatcaacg ctatccttcc ctatgtcacc
    26281 agcgctcaga ttggagactg tacgaacgag cagtatatgt cctccatcgg cgtcagaaat
    26341 tttgatttgt gcatcgtagc tattggagat aatttccaga gttccctgga gacgacagct
    26401 ctcttaaagg atctgggcgc taagtttgta ctctcccgcg ccaaccgtga tattcacgcc
    26461 aagtttctgc ttcgaaacgg cgcggatcag gttgtctatc cagaaaaaga gatggcaatc
    26521 cgatctgcgg tccgctacag caccgacaat attttcgact acattgagct gactccggat
    26581 cattccatct acgaggttcc cgttccctcc agctggatag aaaaaagcat tgttcagatc
    26641 aatgtgcgca acaaatacca catctccatt ctggccgtca agctgggaaa ggagcttcgg
    26701 actcttccag gagcagatta cgtctttatg ggaaatgaga cgctggtcat tctgggagcc
    26761 aatactgata ttaaaaaatt tctctccaca gctaaataag aaatgaagca aaaaggaagc
    26821 gttaagcagc tgttttatgg ccggaacgct tcctttttat ttgtttttta tctgttcttt
    26881 tcagttctgg atcggtaaac ctgtctccta cagctccaca gctgctccag tttcaaggag
    26941 cctgcatgta tccccaaaaa ctgctttcat tttcccaatc ccataaattc cagtgcagtg
    27001 aaccggcatc aagacagaaa tatccatccc tttcagggct tcaatcgtct gatcgattct
    27061 ctcatctcct gccgccgata agtgcatacc ggccaggaca ctgtaaacag gcctgcctgg
    27121 aaaggatttt ttcacatagg acaggcagtt tataatacct gcatggcagc atccggcaaa
    27181 tacgcagagt cctttttctg tctctattac aagaagctgc tcatcctcca tatcatccgg
    27241 ctgtttttct cctcctctgt caatgaaaaa aattcccggt ttcttctcaa acggcactgt
    27301 atagggcacg tttcccagca cccacactcc cggaaaaatt tcctgcttat cctccgtcag
    27361 aacctccgtt tcccgaagaa gctcctgttt ccacggaatg ccgattatgc gatacgtttt
    27421 tttatcatca ttaattgcct gcttatttaa gaaggctgtt ttccgcacat aaacaggagg
    27481 cagcttcctc tgttttgcca gatattccag cccgccgcag tgatcaaaat ggccatggct
    27541 caggataatg ccgtccagat cggacaacgt ctcccctatt ttctctgcat tgtgcagaaa
    27601 aacgtctgtc tgccctgtat cgaacaaaag ctttctcccc tgatgaacaa tcaggactga
    27661 gagtccgtgt tctgccagaa atcctctctt tcctgccgta ttttcattta atactgtaaa
    27721 tctcatatgt tctcctttac ttattccacg aaacgtccta cgtcgagaag cccccatccc
    27781 tgctgattcc ggggaagtcc caaatctacc accctctccc tcaggcggag ctttacctcc
    27841 agattcgtca tatctggata tttttctaaa agcagggcaa tggctccaga taccagaggc
    27901 gtcgacatgg atgtgccgct ctttcctgta tagcagccgc ttctgttggc gcagctgata
    27961 atgtgcgatc cgggcgctat gatatccggc ttcagcacac aggcgctggt aggccctctc
    28021 ccagaatagt cgaccatcct gctcccggct acgtccacct ccttatgatc gtctgagcag
    28081 cccacagtaa tcaccttgcg gctgattccc ggcgtagtga tggtatagcg ccctggaccg
    28141 ttatttccag ccgctaccac cactaccagg cccgcatccc aggcggcgtc tactcccctg
    28201 acaagagctg aattttcatc catccctttc ttattaaagg aaccgaccga tatgtttaca
    28261 atccgtatgc caaactcctc tttgtgttcc cggatccact ttaaaccggc cagaacgtcg
    28321 gaggcatatc catttcccct gtgatccagc accttcaggc tgatcaggct gcaccctggc
    28381 gcgacgccgt gataccgtcc gcccgactcc aggccggcgc ctcctataat ccctgcaatg
    28441 tgcgtcccat gaccgttgtc gtcatagggc tctcttctcc ccttgacaaa atctgcaaag
    28501 cagaccactc tatcctcaaa atcccggtgg ggaaagatcc ccgtatccag aactgctact
    28561 ccaacaccct ttcctgtcag gccaagccga tacgctccgt cgcagtgaat ccaattcttt
    28621 gcctgatcca ttcccagttt ccttcttcct tttctatcag aatattcagg cggacagggc
    28681 aatgtataca tgattccgtc tctatggtat aatgactcca aaatgcagct gtgctgtgca
    28741 catctgccgc tgccgctggc agctaaacta ttttgtcgtt accatatcag gtgaaaacaa
    28801 atgtctgctt cgcagccgct tgttttcctg ctgatatggt atataataac tccaccccac
    28861 agatatgagc aaaggagatg atatcatgac cttcccatcc tttctgcctg cggcaggaat
    28921 cgtcctggcg ggatgtcttc tcgtcatcct gattatatgc aggaaaaagc gcctccccta
    28981 tgaggcaaag ccgcttctca ctaagagaga atatgccttc taccgtcttt taaaacggga
    29041 agccgacgcc agaggatttc tgatctgtcc caaggtaggg ctgaaagatt taatggaggt
    29101 gacggataaa accaatttcc tccaatattt ccgaaaaatt tctcaaaaac atgtagactt
    29161 cgtcatctgc gataaaaatc tccgcgttct gtttgccgtt gagctggacg acagcagcca
    29221 tgacacggca gacgccagaa agcgggatct gtttaaggat caggctttca gagcagccaa
    29281 aatcccgtta aaacgcatcc gctattttaa tgaagcgtct gtaaaagagc tgtttcgctg
    29341 attgccagag ccctggcact ccaaaaggcc agctctgccc tctgcctgcc gcctactggg
    29401 gcggaaattt atagtagagc gtccccggcg cggctcctcc cctgaagcgt atcagttcgc
    29461 tgaccgttac cagctgaaag ccctgttctg caagcgcagg aaccatgcgc tccgtggcgt
    29521 ctgccgtcgg cttatacagc tcgtgcatca gcacaatatc tccgtctttc acttttccca
    29581 gtacggccgc cacagtctga tctgcattct tggtcgccca gtctctcgta tccacgttcc
    29641 acaaaataat cggctgatgg atattggcaa gcaccgttgc attgctgcct cctcccggca
    29701 gacgcaccag ggccggagcc gttcctgtca cagcggctac cgcctgattt cccatctcaa
    29761 tttcttttct gatgtctgcc gcccccagct tctgaagata tttgtggctg tagctgtgat
    29821 ttccaatctc atggcctgac gcctgcattc tgcgcagctc ctcctgatag gaacctgccc
    29881 ggtttcccac tacgaaaaag gtagcccgcc cattatactt ctccatgcag tccataatcc
    29941 tgttgcccac cggcgcgtag ggaccgtcgt cgtaggtaag ggcaatcatc ggcttagacg
    30001 gatcaatcag gcgtcctccg ctcatgatgc gcccgtcctc cgtctttcca tctgcagcct
    30061 gtccttctgc acctgcgctc tggtcttttg aaccggctgc ctgattctct gcgccgttct
    30121 gtccttctgc ctgagcctgc tggttttcct ggaacgcccc ctccggctgc cctcctgtct
    30181 ccgcctgccc gacagattct gtctccatgt tctgtgccgg cccctctgcc tgagcctcct
    30241 tcgcagactc cgccgctacg gccgccccgt cagacgccgg acctgacgga ccgtctgcat
    30301 aggatgtcag cctgcctgcc gataaaagtc ccagacaaag gccaagcgcc agccctctcg
    30361 ctgccttttt tctgattttt tctgcaattc ttcttactgt catcttacac tgctccccct
    30421 ctttctgatg tcttccttga gccttaataa gcccattata cctgtttcac cagtggaata
    30481 caattaagtt ttcctgacaa ttttcttcac aatcggctcc atttcagtca tatgtccaaa
    30541 ataataattg acatatgcct gttttgctcc tatactaaaa gcagagccgt caagaacgcc
    30601 ttcgcgctga caaagccaaa gtcaggagga ttttcatgtc aagaccaaca aaatgccggc
    30661 gtgtatgcca ttttccccct tcgcctggtt tttttcccat tcagaagggc gaggcggaca
    30721 cacctgttat tcttactgta gacgaatatg aaacgatccg tcttatggat ctggagggtc
    30781 tgtcccagca ggagtgcagc cagtggatgg aggtcgccag aactaccgtt cagaggatct
    30841 atgagaacgc cagaaaaaaa ctggctctgg ccctggtgga gggacgtcct ctgcgcatcg
    30901 ggggaggcga ttaccgtctg tgcgacggcc aggaaagctg cgggcacgac gaatgtttta
    30961 aacgcaccta tcatcagcaa tacgaaaaaa agaaaggagc cgatactatg agaattgcag
    31021 tcgcttatga aaatggccag atttttcagc attttggcca cacagaacag ttcaaaattt
    31081 atgacgcaga gggcggggct gtgagacagt ctgaaatcgt cgacaccaac ggaagaggcc
    31141 acggagctct ggccggaatc ctccatgccc tgaatgctga cgttttaatc tgcggaggaa
    31201 ttggccaggg cgcaaaggac gcgctggaag cagcaggaat caaactgtac ggaggcgtat
    31261 ccggcagtgc agacgaagcg gtttcctcct ttttaaatgg aacgctctct ttccagccag
    31321 acgttatatg cagccatcac agcgagcgcc acggcgaagg ccatacctgc ggcgagcacg
    31381 gctgcggcga acatgagcac ggaactcacg gctgcggcgg acactgccag taagcgattc
    31441 attttttatt gaaaaaccgc ccatttttta ttaaaatttt taataaataa attctattgt
    31501 cctatttacc ttatatatgc taagatagaa ttgatttgtg ccttcaggca cataaaacta
    31561 ttatcaatca agaatcgtta cgactgaaag gaaggaaaaa atgggcggat tttttggtgt
    31621 aacctcaaaa acaaactgca ctttggattt attctttgga gtagactatc attctcattt
    31681 aggaacgagg agaggcggta tggctgtcta tggaccggac ggtttcaatc gttccattca
    31741 caatatcgaa aattccccgt ttcgtacaaa atttgagcgc gatgtagacg agctgacagg
    31801 aaatctggga atcggatgta tttccgatat ggatccccag cctctcttaa ttcagtctca
    31861 cctgggaagc tatgctatca ccgctgtggg aaaaatttcc aatgagcagg aattagttaa
    31921 ggaagcttac gaaaaaggcc atatccactt cctggagatg agcggcggaa agataaacgc
    31981 cacagagctg gtggccgcta tcatcaatca gaaagagtct attgtagacg gccttctcta
    32041 cgctcaggag cgtatcaagg gttccatgag tatccttatt ctgactccag agggaattta
    32101 catttcaaga gaccggttag gacgcactcc cgccatgatc ggcaagaagg aaggcgccta
    32161 ctgcgtttcc tttgaaagct tcgcttatat taatctggga tataaggact gccacgaatt
    32221 agggcctgga gagattgtct ttatgactcc ggatggcttt gaaatattaa gcaagcccag
    32281 agaagagatg aaaatctgct ctttcctgtg ggtttattac ggctatccta cctccaccta
    32341 tgaaggcgtc aatgtagagg ccatgcgtta tgcctgtgga aaaatgctgg cgaaacggga
    32401 tcattctgac gcagacctgg tggccggcat tccagattcc ggtattgccc atgcagtcgg
    32461 atatgccaat gaatccggta ttccttttgc ccgtccgttt attaaatata ctccgacctg
    32521 gcctcgttcc ttcatgccgg ccaaccagaa tcagagaagc ctgattgccc gcatgaagct
    32581 gatcccagta gatactctga tccgcaataa aagcctgctt ttaattgacg attccattgt
    32641 acgcggaaca cagctgggcg aaacgaccga atttttatat gaaagcggag ctaaggcagt
    32701 acatatccgc ccggcctgcc cgcctttaat gtttggatgc aaatatctga acttctcccg
    32761 ctccaactct gagatggatc tgatcacacg ccggattatc agagaacggg agggagaaaa
    32821 tgtctccgaa gagctgttag ccgattatgc aaatccagac agtacaaact ataaggaaat
    32881 ggtagaagaa atccgcaaaa aactaaattt cactacgctt cagttccatc gtctggacga
    32941 tctggtggaa tccatcggaa tttctccctg caagctctgt acctactgct ggagcggaaa
    33001 agaatagtcc tgatactgaa attgagagat ccggctgccg gatctctcaa ttctatctgg
    33061 ttctattttt ctttttctct ctccttttcc agaaccatgg cataccgatt gcaggcatcc
    33121 ttcaaacagg cgataagcgg cttctgcgtc atagcaaaat aacggcttct gatttccttt
    33181 tccagcagct ccatatctgt tttcaggctt tttccaacta tcatatctgc tacaaaatcc
    33241 ctggttactc ccaaaatcgt attgcagtcc atattgataa tggttccgct ctttttctcc
    33301 agtaccaggc tgatgtaaaa ctccccgtga aggctgtaaa tggcgtcttc gcggctgggc
    33361 ttggcctgtc ctacaattaa aatagtattt ttttcatatt tcatatactt ttctcctttt
    33421 acagactact attctgtatt atccgcacct ttgtcacagc aggcgcagaa ataacaaatt
    33481 tttcctccaa aatttgtcgt gccggtctga tgatagtcct tgacaccccg tgttaaaaac
    33541 ggtacaatga tactgaaaat catacggatt cttttattta tagggactcc tgcccggatg
    33601 atcccattgt aaataagagc catgaatctg aacaggagga gtggcttttt ttgtttgtcc
    33661 agactgtatc ctgacagaaa acagacagaa aaacagctca aaatgggagg ttcaatatga
    33721 cttttttcag taaacttaat tcgattatga gacaggattt cggcagccgc ggacttatga
    33781 aggctcttcc agaggcggat ctggatcttg tttccagaga actcgcgcag gccaggcgcg
    33841 ttcttattct cactggcttt cctgttatct gccccgacca aacagtgaca ggagagacgg
    33901 acggaccttt gggaaccgca gatttagcct ttgccctgga agcaaacggg tgtcaggtta
    33961 tggctgtgac agactgccat tcctcagcta ttctcaaggc tgccctctct gtccgctgcc
    34021 gcgaagccag aatagctgta attccggaga caggcgctga atcctttgca gaggatcttt
    34081 tagacgcctt ttctcccacc catgtagtta ctctggaacg gcctggcaaa gcctgcgacg
    34141 gccattatca caatatgcgg ggtattgtca ttgattcaat gactgcggac gccgactgct
    34201 ttctctccct tgccagagaa aagaacatct gcacaatttc cataggggac ggcggaaacg
    34261 aaatgggtat gggcgcgttc cgaaaagaga tagaatcttt cgttcccctt ggcagcgaaa
    34321 tctgctctca gcagggtgcc gactatgcct tggccagcgg agtatctaac tggtggggaa
    34381 tcggagccgc cgctcttctc tccagagaaa cgcagaaatt tctgcttccg gatgaagagc
    34441 aggaaacgga aatgctccgc cgcgtccttc aggccggagg agcagacggc gccacaggac
    34501 ttcgtgaaat gactgtagac cgtctccccc tggctgtaca tctggaaatt ttaaaagaag
    34561 tttcttccct ggttcttgaa gaactgaagc tgggagccgc ctgattcctg tcctgaccta
    34621 caaaggagac ttcatggaaa tcaattacga ttactaccgg attttttact atgtagccaa
    34681 atacaaaagc ttcacacagg cggcccatgt cctgctgaat aatcagccta atatcacccg
    34741 ttccatgaac aacctggaaa atcagctggg atgtcagctg tttgtccgtt caaaccgggg
    34801 tgtagaactg acgccggaag gggagcgcct gttttctcat gtctccatcg cctacaggca
    34861 cctccaggct gctgagatgg aactgggaca gaaccgtgaa cttcaaagcg gcagcgtctc
    34921 tgtcggtgtc agcagcagcg cgttccatga agtcctgctt ccaaagctga tcaagtttca
    34981 cagcctgttt ccaggaatca ggctgcgctt ggtatctgcc gacaaaacgc aggctgtcct
    35041 gcttctgaaa aaggagcgga ttgacttcgc cctgtctgct ctgtctgaag aaccagagaa
    35101 aacagagtcg ccattcagag aaacaccgct gaaagaattc agggaagtcc tgattggatc
    35161 cagacaatgc agctttttag cggatcgtcc cagatatccg gcagaactct ccggatttcc
    35221 cctcataaca ctgggaagga gtgccgaatc ctttgaattt tatcgttctt tttatcaaag
    35281 tctgggattc tccccggttc ctgatatcga ggcatcctct gcagaacaga tgcttagtct
    35341 gatacaaaac ggtttgggaa tcggctttct ttctgaacgc ctggctgaaa ctgctctgtc
    35401 ctccggctgt gttgtccgga tccccctggc caaggagcct cccgccaggc gctgcagtct
    35461 tatcgaagat tcaagccggc ctttaagtca gccagctgcc cagctggtaa atctgcttct
    35521 ggaacaggaa aaaacagaat agaaaaacag gagcagtctc ctgccagcac attgggctgc
    35581 agagagatat ctgctcctgt ttttatttca gccaggaaaa gctgatttta gcacgccctt
    35641 aaaactatgc tcttgggcct gcgttcttga tctcctcagg catatctgga tacttcttat
    35701 caaagttgtc cttaaacatt ttagctaact ttgcagcagc ctcgtcgtag gcagccttgt
    35761 cagcccatgt atctctcggg ttcataatct cagccggagc gcctgggcag gactgcggaa
    35821 catctacatt gaatacgtcg tcatgcttgt actctgcctt ctccagctcg ccgtttaatg
    35881 cagctgtaac catggctctt gtgtaggaga gcttcattct gcttcccact ccgtaaggac
    35941 cgcctgtcca tcctgtattt acaaggtaaa cctttgtatt gtattttctg attctctcac
    36001 ctaacatctc tgcgtataca gacggattta acggcatgaa cggctcgccg aacagggtac
    36061 tgaaagttgg ctgcggctcc ttgattccgc gctctgtacc ggctaacttg gatgtaaatc
    36121 ctgttacaaa gtggtacata gccgcattct catccagtct ggagattgga ggaagcacgc
    36181 cgaacgcgtc agctgtcagg aaaataacta ccttcggaac tccgcctacg cctggaatct
    36241 gcgcgttgtc aatgtaggta atcggatagc ctacacgtgt attctctgtg atggaatcat
    36301 cgtcgtaatc aggaattctt gtctccggat caatgactac gttctctacc tcgctgccga
    36361 agcggattgc gttgtagatc tccggctcgt tcttcggatc cagattgata cattttgcgt
    36421 agcagcctcc ctcgaagttg aatacgccgt tgtcacacca tccatgctca tcgtctccga
    36481 tcagctttct tgccggatct gcagacagag ttgtctttcc tgttccggaa aggccgaaga
    36541 agatagccgt ctcatgagtc tcaggatcca tatttgcgga gcagtgcatt ggaagcacat
    36601 tttcctcaac cggcattaaa tagttcataa cagagaatac agatttttta atctctcctg
    36661 aatactgaga accggcgatc agtacaattt tctcctggaa gtttacgata atagctgcct
    36721 cagagtgtgt tccgtctacc gcaggatcac aggtaaagcc tggagctaca accagtgtga
    36781 aatctgctgc accataggat tccagttcct ctgctgtggg tctgattaac agctgatgga
    36841 taaacaggtt ctggcttgcg aactcattga caaccatgaa ctttctggtg tacttcttat
    36901 cagcgcctgc aaagccctgg aatacatata attccttatc tgccagatat gtgaacattt
    36961 tatttttaat agactggtag gcatcttcag agatagcgac gtttacgtct ccccaggcaa
    37021 tcttgtcatg tacatccttt gtatcaacga taaatttatc tttcggtgag cggcctgtat
    37081 acttgcctgt agtaacagaa agagcacctg tatttgtcag cactccctcg ccgcggcgaa
    37141 gagcctcctc taccaggcgg gcagggttta agttgtagtg aaccttgcct gtggtgttct
    37201 gaattccaat catttctaag ctgtggtttt ctttcatgaa attgcctcct gtcagttata
    37261 attttttacc tatagattat atattacact tattatgcga catctgtaaa atatattttt
    37321 gatattacag tcatatattt ttgatatgtc tcaaaaattt cctctttaat cttcaaaaca
    37381 gccgccgcag aactctctgc agcggctgtc tgaatagccg gctctctcct gactgttaaa
    37441 ttgtcctgtc cctggcagct gtttcattaa ataatgcctc ggcgcatcac aatgtcaatc
    37501 cgctccttat caaggcttct gataacctcc acagccatct ttacggtagc gtcaatatcc
    37561 tccatggcac agaaattata atgagtgtgc acgtaccggg acgggattcc cagaaccaga
    37621 accggtactg cctttcctgt caggctgatc tttcctgcgt tggtgctgcc tccccgccgt
    37681 acggcgtcct gatatttgat gccgcactta tctccgattt cctgggccag gcggataaat
    37741 tcaggattgg acacatagct ggcatccata tgtcggatct gggttcccgc cttcaggctg
    37801 cactgggcga taccagggcg gaaataaaag tcgtccgccg gagatccctc aaacacaatg
    37861 gccaaatccg gaagaagctg ctgggaggtc acctgggctc ctctcgttcc tacctcctcc
    37921 tgagcagcga atccgcccac tacctccacg gccagctgct ctgactcagc ctgaagcgcc
    37981 ttcatggtgc tcagaatgct cacgcagccc agacggttgt caaaggcctt tccatagcag
    38041 ataccgtgat cttcatcgta ctcaaacttc acgtccggca tcaccggatc tcccactgcc
    38101 acaccgtagt cctccatgac ctctctccgg ctggaagccc ccacgtcaat tctgatatcc
    38161 tcgatattta aggaattgtc cgcccgctct gcggctgtca gaaaatgcac tggcttggag
    38221 gtggtgattc ccctgatttt ctttcccgcc ctgttcttta caatgacaga gtgggccgga
    38281 atattcgtat tgtgaatgcc gcccagacag ataatatcaa gcaggccgtt ctcctcaata
    38341 ttctgaacca taaagcccac ctcgtcggag tgggcgtcta acatcagaac cggccgtttt
    38401 ctgtccgcct cgggcataca ccgtttcttc gctgcctcgt ccatgtaggc gtatacattg
    38461 tgcatggcgt cgtgctccag ataaaggctg ccgctgtgct tcttcaccgc ctgcacgacc
    38521 tcttcctcaa agccgctggg gccgaaggcg ttggtaaggt cctctaccat ttttaaatct
    38581 gccatagttt ttattcctcc tgtctgcgtc agctctgtgt tctgtcctat tttagtaaac
    38641 cataaaggaa tgagctgtca caatatcctt ataatctctg ctgactaccc ggtttgtcct
    38701 ctcgtccacc cgctctgcgc ccgggaagaa ggacatctgg tacgctttct tcagatcctt
    38761 gtaattcact acgtactcga actgctccgg catggcaatc cggcaggcct tcagatctcc
    38821 gctgagggct tccttcacct tctcttttaa aagccggtct gcagcagcca cgctcatatt
    38881 gatggtgcag gctcccacgc ccttctttac agccgctgtg gtgatgcctg gaaccatttc
    38941 cctggccagt ccgcagattc cctcatctcc ggaaataaag acggccggca cgcccatcat
    39001 ggccgctgtg taggtattga gcataaactc gctcatcacc tttccgttta aaagaatctg
    39061 gttgctgttt cctgtagagg tatggctgat gggattgccg ccgtttccag ccggcgcgtg
    39121 atagcctacg tagagcacgc cgtcaaaggt ctcgtccagg ccaaacatca tattataagg
    39181 atggccgctc tttccgcgga tcagtgtcac gccctccggc atggcggtaa agtcaatgtt
    39241 agtggcgtct ccgtgtccgt ccttgaccac tatctcgccg gctcctgcct ccagagccgc
    39301 ctggcagaca attcttacct catctgtcat ccgttttgca aactgccggt actccggcgt
    39361 ctccttatgt gtttcgctgg caagcgtcgt gccgacgcag ccttcaatat cagcgctgat
    39421 aaacagcttc ataacgctca tctccttttt tcatgtcctc tgacgcgcta tttgacgttg
    39481 ggattttcct tatcgtacag gtggcagtat acaaagtgat cctctcccac ctggtatttc
    39541 ttcggtgctt ccttcttaca gatttccatg cacttgggac acctggtgtg gaacttgcag
    39601 ccggacggtg gattgatggc ggaaggaatg ctgccctcca gaatgattct ctccttcttc
    39661 accgtcggat ctggaatcgg gactgctgac agcaaagcct gggtataagg atgcatagga
    39721 ttcttgtaca gattttcctt atttgccttc tccacgaaat tgcccagata cataacgccg
    39781 atccggtcgc tgatgtgctc gactacgctc aaatcgtggg caatgaaaat gtaggtcagg
    39841 tggtattcct tcttcagctt gctcatcagg tttaatacct gggactgaat cgacacgtcg
    39901 agagcggaaa ccggctcgtc ggcaataatc agctgcgggc gcactgccag cgctctggca
    39961 attccgattc tctgtctctg gccgccggaa aactcatgtg gataacgtct ggcatggtaa
    40021 tcgtccatgc ctacctctct cagcaggcgc acaaccgcct cgtcgatctc ctgctttccc
    40081 ttcacaaggc cgtgaatctg cagaggctcc gccagaatgt cgtgaatgga cattctggga
    40141 ttcagggaag cgtaaggatc ctggaatacc atctgcacct ttttcctgac gttgcgcatc
    40201 tttttgctgt tgtagcctct gatatcctca ccgtccagaa tgatttttcc gtctgtgggc
    40261 tcaatcagct tgcagatagc cttgccgagc gtagactttc cgcagcctga ctctcctaca
    40321 atgccgaata cttcgccctt tttcacctca aaatctacgc cgtccacggc ctttacaaag
    40381 gccttggttc caaataagcc gtctgacaca ggataatact gtttcagacc ttctaccttt
    40441 aataaatctt ctgccataac cgtcccccct tatttatcgc agagccagca tctgctctgg
    40501 tgtccgtttc cgagatcgaa gaatcccggc tcttcctctt tgcaccgctc tgtggcgtaa
    40561 gcgcacctgg gggcgaactt acagcccttt ggcatatatt tagggttcgg cacgtttcct
    40621 gggatggagt ctaactcctc cacatgctcg cccagcttcg ggatggactt taacaggccc
    40681 tgggtgtagg gatgggccgt ttttccaaaa atatcgtaca catttccctt ctccaccacg
    40741 cggccgcagt acataaccac tacctcgtcg caggtctccg ctacgactcc cagatcatgg
    40801 gtaatgaaca tgatggaggt tccgatttcc tttttcaggt ggttcatcag gtcgatgatc
    40861 tgagcctgaa tcgtcacgtc gagagctgtg gtgggctcgt cggcaatgag gatcttcgga
    40921 ttgcagacaa gagccatggc gatcatgacg cgctgtctct gtccgccgga cagctggaag
    40981 ggatactcgt ttacgatccg ctccacccgt ggaagtcctg tctttttcag catctccaca
    41041 gccatggact gagcctcttc cttcgtcttg ttctggtgca tcttaatggc ctccaccagc
    41101 tgatctccga ttttcataac aggattcagg ctggtcatag gctcctggaa aatcatggag
    41161 atctgatttc ccctgatttt tctgcgctcc tcggcgctta aattcgtaat atcgcggccg
    41221 tctaagagga tctggccctc taccaccttg cctgtggttc ccattaaaag tcccatgaca
    41281 gacagggcgg ttacgctctt tccgcttccg gactctccta cgattccaag ggtggagccc
    41341 tccttcagct cgatatccac tccgtccacc gacttcacca ccccattgtc ggtgaagaag
    41401 taggtgtgca tattttttat ctcaagaatg tttttccttg tatccatttg attcctcctt
    41461 ttgtcctctg cctggttaat ctgtcagctt cggatccagc gcgtccctga ggccgtctcc
    41521 taaaaggtta aagcacagaa ccgtcaggaa aatcgcaagg cctgggaaca gagtaatatg
    41581 ccagctggta gccatgtagg ttcttccgtt gctgagaaga aggccccact ccggtgttgg
    41641 cggctgcgcg cccataccta agaagctcaa gctggatgcc gtcagaatgg aggttccgat
    41701 ggacatggtg tactgtacga taatgttcgg aattgcgctt ggcagaatat ggcggaacag
    41761 gattctggca tcgctggcgc ccagattctt cgccgcctgc acaaacacat tccctttagt
    41821 agctaaggta gtgcttcgca caagccttgc aaaggtcgga gtgctgaaca ctgctaccgc
    41881 gatgactacg tttgtcatgc cgcttcccag gatagcgatg atggcgattg ccaggataat
    41941 gcctgggaac gcaaacagcg tgtcacagat tctcatgatg atggagtcca aaagtccgcc
    42001 gtagtatccg cctaagagtc ccagaatggt tccgcagact gcggcgatgc tgactgaaaa
    42061 cagtcccaca ctcagggaaa tcctggttcc gcagatgatt cttgagaaga gatcacgtcc
    42121 aaattcatcc gttccaaacc agtgagctgc actgggcccc tgcataatcg ccgtataatc
    42181 atattcattg attccataag gtgcaatctg gtagcttacc actgccagca ctgccagcgc
    42241 aataataaag aacattgctg cgattgccgt cttctgtttt ttgaattttc taacaaaatc
    42301 tttaaatggc gtattgatgt ccattttctc atttaatact ttttccttcg ccataactgt
    42361 tcccctttcc cattaattca gcttgatttc cggattcagc agagcataga ggatgtccac
    42421 caccagattg atcactacaa agtgcaggga gaaaatcagg atcagggatt ggatggcatt
    42481 gtaatctctg tagtttacag attctacgag aagggagcca agtcccggga acgcaaatac
    42541 agattctgtt acaacggatc cgcctaacag gaagccgaac tgaagtccca cgacagtcac
    42601 aacggaaatc atggcgttcc taaatgcgtg cttccagata acggttctct cctttaagcc
    42661 cttggctctg gctgttctga tatagtcctc tttcattacc tcgataatag aggaacgtgt
    42721 aaagcgggca ataatcgcgg caatactggt tcccagagca atggacggga ggataaagct
    42781 tttccaggaa tcagctcctg tcgtaggaag ccattttaaa ttaacggaga agacagacca
    42841 taatgagaag gaagccgatc cagaaggacg gcatggaaat tcccgatatg gccatcgtca
    42901 tgccggtgta gtcctgccac ttggatcggt gttttcctga ccagactcca agcagcacgc
    42961 ccaccaccac gctccaggcc agactgccca gagtcagctt aactgtgttc atatagcgga
    43021 ggctcacctc tgtagctacc ggacgtttcg tacgcagaga cattcccaga tcgccgtgga
    43081 acaatccagt cacatagtcc acgtactgag tcacgatggg cttatttaat cccagctcct
    43141 ctctcactac ttctacatcc tccagcgtag cctggggacc ggccaccaga cgggccggat
    43201 cgcctggtat caggcggaca aaaaagaaaa caaaggttgt aacaataatc agtgtcggga
    43261 tcacaccgat gatgcgctta atgatgtatt tgagcatccg ctcactctcc cctctctcct
    43321 tagtctcaaa aatggtttgg cgatcctctt actgctctga ggacgccaaa ccattttcag
    43381 gcaaagcctt ttattttact cagatcctat tttgccattc ttgcgtttct gatgttcagg
    43441 cagttatccg gatatacctt tacattggca atcttgtttg tagttgccca tgtattgtaa
    43501 tcatttacca ggcataccat cgggcagtcc tcccaaagga tatcctgcgc ctgagcataa
    43561 aattctgctc tctttgtctc atcagctgtg ctgagagcat cgtaaagaag tttatctacc
    43621 tcttcgttct cataataaca gatgttatag ctcatcggcg gctcagactc aacagcaact
    43681 aatgggcgga taccccagtc agcatctcct gtagaggagg accagccaat tacatacatc
    43741 tcaacctctg cctcagcacc tggcttatcc acattttcta ccttgtcatt tacaaccgca
    43801 ctctccagag cattgatatt catggtaatt cccacctgag ccagctgctg ctgaaggaat
    43861 tcgccctgct ttaagtttcc tgtagtgctg gcgcagatta aggtacactc aaatccgtcc
    43921 ggatatcccg cctctgctaa cagctccttt gccttctccg gatcatatgg atacggatcg
    43981 tttcctttgt agtgctgggt agccggtccg ataatggagg aggctgctga ggaaaggccg
    44041 ttctttacaa ctgcgatgta agcgtccttg ttgatggcgt agttgactgc ctggcggact
    44101 ctcttatcgt taaacggagc cttctggttg ttcatgaaca ggtagcgcac taccatgccc
    44161 tcttctgctc ctacataaat gtttgtgtct cctgccaaag cctgcatgct ctctgtagga
    44221 accggccaga taaagtctgc gtctccggac tgaagcatcg ctactcgtgt ggcattctct
    44281 gctaccgggc ggaaggttac gctcttaaag cctgcatccg gctctgctaa ggctgtgccg
    44341 ccgcagattt ctgcgtcgta gccccaccag tccttgttca gagtaactgt cgcgtgatcg
    44401 cctgcgatcc actctttaaa tatgtactgt cctgttccta ccggacgctc tgcacaggcg
    44461 tcgttgccct ctgcgattac cttcgggctc atcagcacgc aggccggatg tgccagagtg
    44521 gagataaacg ctccgaagga ctgggaaagc ttaaccttca cggtataatc gtctacgatc
    44581 tctgtggagc caatcacatt gcacagaaga gtggttctct taagtcccag ctccttgtca
    44641 gcccagcggt ccaggttggc cttggctgcc tctgcgttaa acggcgtacc gtctgtgaag
    44701 gatacgccct gtcttaaatg aatcacgtac tcagtcgcat cctcgttagc ctcgtaatcg
    44761 gtagccagca tcggaataat cttcatattg tcgtcaaaac cgaacagtcc gtccatcatc
    44821 atcctctgaa tgccgccgga taacgtatca ctggtatcca taggatccat ggtagtaaag
    44881 tctaccagta tcgctcctac aacatctgtc tcctgggata cagattcgcc agcaggcaca
    44941 gtcacctctg cagccgatac aggaatctct gcctgagtgc ctgccccctc tcctgccgga
    45001 gccttgcttt cgcctgtctg tcccgtggtt tcttttccgg aatcaccgga gccgccgcag
    45061 ccggccatgg acagggccat cactcctgcc atagcgagag ccagcagcct ttttgctctc
    45121 aacttcatag tttttcctcc ctttcttttc acagcgtctg cctcctggac tttctcactg
    45181 taaatttctg aatttttgat ttattatccc ataaacctgc tgttatgtca acatttcatg
    45241 ttataaaatc tctattttct ttttatctta taaatattga atatcactgt taatatgtta
    45301 aaatttagac atttttccat ctttctacgg attcattctg gcatttctga tattgagtcc
    45361 tccatctgga taaatcttta cattggcaac atctgctgca gaagcccatg tgttataatc
    45421 attggcaaaa aataccactg gacactcctc ccagataata tcctgggcct tggcataaag
    45481 ctctgcccgc ttctcctcat ccgccgtctc cagggccgcc ttcagacagc cgtccatctc
    45541 gtcgttctcg aaatagctga tattgtagct cttcggaggc tcggattctt ttgcaagaac
    45601 cgggcggata ccccagtcgg cgtctcctgt ggaggaggac cagccgctca tgtacatctc
    45661 cacctcgacc tctgatccag gtccctcggc gctctccacc ttctcgctga caatggcctt
    45721 ctccatggaa ttaatgttga ccgtaatgcc tgcctgagcc agctgctgct ggataaattc
    45781 gcactgcttt aaatcgctgg tggtcgtagt gcagatcaga gaggtctcaa agccgtccgg
    45841 atagccggcg tctgtcagaa gcttcctggc cttctctaaa tcgtaggcgt aaggctcgtt
    45901 tctcttgtag tgctgagttg caggccccag aatagaagtg gccttagagg ccaggccgtt
    45961 cttcaccacg gcgatgtaag cgtccttgtc aatggcgtaa ttcatggcct ggcggactct
    46021 cacatcgtta aacggcgctt tctgcgtatt cataaacata tatctgacta caattccctc
    46081 gtctgctccc acgtacacgt tttcgtctgc agccagggtt tccatgctct ctgtgggaac
    46141 cggccagata aaatctgcct ctcccgactg aagcatagcc acgcgggagg cgttctcgcc
    46201 taccgggcgg aaggtaatgc tctgaaagcc tgcgtccggc tccgccagcg ccttgccgcc
    46261 gcagatctcc ggatcgtatc cccaccagtc cttatttaag gtgactgtgg tgtgatctcc
    46321 tgcaatccat tctttaaaca gatactgtcc cgtccccacc ggtctctcgg cgcaggcttc
    46381 cttgccctgc tcaatcacct gagggctcat cagcacgcag gccggatgag ctaacgtagc
    46441 cacaaaggcg ccgaaaggct ctgtcagagt gacctttacc gtatattcgt ccacagcctc
    46501 tgtggatttc agcacattgc agagaagcgt cgtccgcttc agccccagtt ccttatcccc
    46561 ccaacggtca aaattagcct tggccgcctc tgcgttcagg ggcgtgccgt cggaaaagga
    46621 gatgccctgt ctcaaatgaa tcacatactc tgtggcgtcc tcgttggcct cgtaggactc
    46681 tgccagcaga ggaataatct tcatctcgtc gtcaaagccg aacagtccgt ccatgatcag
    46741 gcgctgtacg ccgcctgaca gggtgtcgct ggtatccatg ggatccatcg tcataaaatc
    46801 caccgacata gctgccgtca cgtccgtttt ctgtgatacg gaagcgccct ccggcaccga
    46861 cggctctgtc ttcgatacgg gaagagccgt ttcagctgcc gcctgttccg ttcctgtctg
    46921 agctgtcgtt ccttccttcc cgtttcccgc tcctgttccg gattcctgcg tctgggaagc
    46981 gttcccgttt cctgtctccg acgaaccgca ggctgtcata aaaagagcca tgcttcccgc
    47041 cgcgctgcca gccaaagctt tgtcctgcaa atccttgatt tctttctcat cgttccttcc
    47101 tccccttcct gacgactgcg cctcactgaa tttttcgcgc attttaatgc gctgtcaata
    47161 tgacgcttta acctgctgat tcaaaatggt ttcgtatatt attgcacatt tgactattca
    47221 ttgcaatatt tttttaattt atttttattc ccggttcatt ttcttttttt ctatgacgat
    47281 tcttcattta gtgctataat tagaatatct tatatactat atctatcttt taagggggtt
    47341 ttacctatga cgaaaaagcc gcttatcgga attatcacta ttttagatgc ccaggcagtt
    47401 cccagggtct cggtcaatat caattaccag aatgccgtta tccgtgccgg aggcgttccc
    47461 atccttctgc cggttacaag ggaggaggag ctgctggcag gctatgcgga tatgtgcgac
    47521 gggttcctgt tcagcggcgg gcaggatatt tctccctgcc ggtataacga actgcccagc
    47581 cgcctgaccg gccccagcag cctgctctta gacgactacc agctgaacct gatgaagctg
    47641 gtgctcgatt caaaaaaacc ttttatcgcc atctgccgcg gcattcaggt gctgaacgtg
    47701 gcctgcggag gcactctcta ccaggatttg acagaatttt ctcctaccgt ttccaagcat
    47761 atgcaggaaa cggatcgggg cgatgtgagc catcctgtca ccattcagga aggcacccgc
    47821 cttcacagtc tgtttggaga tcgaatctgg accaacagct atcaccacca ggccttaaaa
    47881 cgtgttccag gctcactcaa agtggcggct cactccgatg acggcgtagt ggaagccgtg
    47941 gaggtgcggg attatccatt cggcatcgga ctgcagtggc atccggaagc catgctggcc
    48001 tctgacgacg cgatgctgcc tctgtttcag gccttcatcc aggcagctgg agacagacag
    48061 gacactggaa aataacaaat atgcgaaaag gaaaagagag gacgcgcgtc ctctcttttc
    48121 tgttttttct attctgtttt atgtttttct gttctgcctt ctgtcaaata cttcttctga
    48181 aatactactg cagaaactct gccaggctgt aatacacggt tccatccagg ccctttgtcg
    48241 taacggcggc tgtcatggag tttaatactg cctcctctgt ggcctctgcc actgcctgga
    48301 aaggcccgtc cataagattc tcatttaaac acctatgctc cagaacagcc ggctccttcc
    48361 catccggaac ccggcctgca gtggtaaagc ctatcatcac ttccccgctt ccgtggcccg
    48421 tgtaggagcc tgttctggca agtccgttgc acattctgcg gatcagacgg cgcagctgtc
    48481 tctcagacag aggcagatcc gtggcgcaga tcatcataat ggaaccgcgg tcttcctccg
    48541 taccgcggaa catggaattt ttcaccgccg tcctggcctg ctcggacggg aaggggcgtg
    48601 ccggatcttc tcttccgtct gcagccgcca gaatctctct ccccacaggc ctgccgtcta
    48661 tggtcaggaa acgggttgcc ccaaaattgg actgtaccag aactccgatg gtatactctt
    48721 tttctccgac agccaccacg cgggaagcgg aaccgattcc gcccttgaag ccgtagcaga
    48781 gcgttcctgc cccagctccc acacagccct cctcaaactc ttctcccgcc tgatcgattg
    48841 cggaaaatac gtcttccttc ttcactgccc ggagagaaat cctgttaatg cggctgtcgt
    48901 tgcactctcc caccacagga ttcacagagg aagcctcagc gccgtccgcc tcacaccgct
    48961 ttaaggtata ttccaccagg gcgtctgcca caagccccac gttcaaagta ttggtcaggg
    49021 caatgggcgt ctccagggtt cccagctcct cgatctgggg aaggccgcag gtttttccga
    49081 atccgttgtg cacataagcc gccgcagtgc atttattcag aaaaatattg tcctccaccg
    49141 gcagaatcac agtaacgccg gtgtggattc cctccctctc cagcgtcctg tggccgactt
    49201 tgactcccgg cacgtctgtg attttatttc tctttccctt tggatgctcc ccaatggaaa
    49261 ttccatagtc gcagattctc tttttcattt tgctgaacct cccttttctt ctgtcctatc
    49321 aagcacatat caaaaactgt tggacaaaag acttcttttc ccccataata tcttatagaa
    49381 atgcagattg tcaaaggaat ttttcaatgc agggggtaaa ttatgaaata tttgaatcaa
    49441 ttagagtatc cttccattcc ctatcccacc gatatcagcc atccgggaag tcctctgaac
    49501 agcggttctg tgaaggaagc cggatgcggc ctgtgctgcc tggcgatggc tgtggacagg
    49561 ctgaccgatc agtctgtttc cctgaaaaag ctggtttccc tgtctgtcaa gcataaggcc
    49621 aatctgcttc caggcacaga tatggaaatt ctggggcctg tggtggccag gcagtttcat
    49681 ctggaatatt ccaccacaga aagcgtccgc accgctgtcc gctgtctgaa gcggggcggc
    49741 tgcgtcattg ccaatgtagg cggagacagg gaggggtaca caggagtgtt cgcccatgag
    49801 ggacatttca ttcttctcat tgcaagcgac ggagatcaaa tctgtgtcct ggatccggct
    49861 ctcaggcccg gacggtacga cgagccgggg cgcaggggca aggttctctt agacgagccc
    49921 ttcgcctggt gctctctcaa gcttctcacg aaggagacag ataacagaag tccaggcttc
    49981 tacctgtttt acagaaaagc gcctcttgcg gccggaaaag ttctgtagaa gctctgaacc
    50041 gggggctgcc gcagtgcgat tcctgcggag cattttttat ttcataggac gcgctttttc
    50101 ctatgaagca aaaaactgcc tggcaggacg cttcctttca tttaagcgtc ctgccaggcg
    50161 tttttccctc ttgctatagc cttagttcag ctcaatcttc tcagcctgat ccgggaagaa
    50221 ggagttcttc atatcatact tattgtggtg agtgaaatcg tagagggctt ttccgttcag
    50281 gaaataattt ctctgatatt ttccctcttt tactaacagc cagttctccc gatcccatgt
    50341 gagatagccg tcctcatctg ttctcggctc tgaaaatacc agatccacct gacggttgga
    50401 atctaagagc ttcatcagat cctccactgt aacctccacc tcggcttttg cctgtacatc
    50461 atatgctttc ataaaacaaa tatcctcccc tttttatgat gtttgttcca ttatgccact
    50521 attttcccgt tccgtcaaat ggcttttccg ctgtctcaag acgatattct acagtaaatt
    50581 cctttccaga gcgcaggaaa cggccgccgc agaatacctc ccccgactgg ttgtcgtacg
    50641 gatcgtcccg cagtccctcc tcttctcttg agaagctgtg cataaactgg gaggcatacg
    50701 gaatcctgta gggatccagg ttggccccat agtaggcccg tctcttctca tcgccctggc
    50761 ggaaggcgga tcctccgaag gagcagtccg cgctcagcca tccgaacggc gccacgtaat
    50821 actgggccca gtcgtggctt cccacagtca gaggcgtagc gtaaaggcct gactgccatc
    50881 tggccggaat cccggcaatc ctgcacatgg tgataaagag cagcgcctgg aagccgcagt
    50941 cgcccttcct gttggcagcc gtaaattccg gtatatcctc cactgtgctg tagcttctca
    51001 caaaggaata tttgacctgg gaggtaataa acctgtagat cttctctgcc gccagaaggg
    51061 gattttcctc tccttctgtc acgctccttg tcagttccct gaggtaaggc gtaaagcgga
    51121 tgtgaggcgc ttcctctcct gtatagaagg acggctggga gaagagaacc tgggacggat
    51181 ccggatttct gaacaccgtc tcattgtcaa actcaaactc tgtctgccat acctctcccc
    51241 cccggatcac cgtttcaaac cgtgccgttc tctgaggata ggagccgttg tccacagata
    51301 ccggctctcc ggctgtgcct tcaaatccca gcaggcgcag gttccttacc tgggcatact
    51361 ccaccggaag cggcatgtag acatgagcgg ttttgcccat gcaggccttc tccgcctcag
    51421 gagtcagaga gagtctggtc aaaagacgca tatggacagt ccggccgccg tgttcttcca
    51481 tcaggcggac gttctccctg agaagggccg cgttcttttc gttatcctcc atggtcccca
    51541 gaaagcgcgc tccatagtcg tctctcgtct tcatcagatt ctcgaaaaac agctcgtgaa
    51601 actgtactct gccgtttatg taaatccagt ctgccgtatt ctcctcccag agtgtttcca
    51661 gctccttgtc cttaaaatct ctgatattcg ccctgagaag cgctaaagct tcctcataag
    51721 aatatggata ctgggacggg attctggcgg ccagaatccg ctccagctga agacgctttc
    51781 tcagcggagc agggagcgtt tcatcggcaa ggcgtctgtc aatcacagaa atcagccttt
    51841 cgtaatctcc tccccacttc agtttcatta aatcttccgg aagcggcaca tttaaatacc
    51901 gcatatcaag cgctgtctta tctgccattt cgtgttcccc tcttcttttg tttttgcttc
    51961 ttctgttttg gctccttctc tttcagccgt ttctacttct gtctgttcca gacgtatctt
    52021 ccccttggtc ttctcctgct ctgcctgtaa ggacgcctct cctgtattcc ctcctgtttt
    52081 tgagacgctc cgctctgttc tgctgccgtc tccggccgct tttcactctc aggctgcttc
    52141 tcctgctcct gtacagcggg cctctcagtg gaactctcct cctgaatcaa ggcttttttc
    52201 tccttctggc cgccctgttc ccgtctgtcg tctgtccagc ctgttctttt tttgctgcgc
    52261 ctctttgggg ctccctcctt tgccggctcc ggccctctgc gctcttcctg ctttttctct
    52321 cttcccactt cttcgcaggc cttattttcc ttctgctctc tgagcggctc tgtctcctgt
    52381 tttcggttct ccgccgaaat ggtctgaatc tttatcggtc cctccggctg aggcctgccc
    52441 tgatttctgt tgtttctgtt atttctgctg tttctgcggt ttcttctgtt ctggccctct
    52501 tccgcctgtc tggacgattc cttctccttg gcaggctccc cggaaggctg ggcctgtctc
    52561 tctcccttgt ccacaatgat ttcccggacg ctctccagct cctccccgct ggccgctatc
    52621 gccggccgcc gcttcatgct gattttcttt ccggacatct cctttccatg ccagaaatcc
    52681 tccatgctgc caaaaccgtt gtcgcggctg acaatgataa actccttctc tgatgtgctt
    52741 ccaatcagat atccgcagta gctggacagc tgaaaatcca aaaaattctt tcctgtctta
    52801 tctactttaa tgtatctgac ttccgccctg gaagaggcaa tctcaatatg tctctcaaaa
    52861 ggaactgcag cggcctgctt tccgtaaaaa atcacaacgc ggtcacgatc tgacagcttt
    52921 tccacgccgt ccattcctcc gacccctaca ttctcaaaat ctaccaaata cgtgctcatg
    52981 tatttcctcc atgactgttt ctgttttgca aactccttct ctgacgctga tattattctt
    53041 cggcttccgc cccgtcgctc tccagaagat acggcgtcac ctggtaaacg tagaaattca
    53101 gccagttggt atacagcgtg ttggccatat ttctccactt cagggcagga attgaaaacg
    53161 gatcgttatc ctcatagtaa ttgtacggaa tctccggatt cattcccttc ttcagatccc
    53221 tgtggtactc gttgttcagc gtcattctgt cgtactccgg atgtccctgc atgaaaatct
    53281 ggcgcccgtc acggctcatc acaagaaaaa ttccagcctc cctggacttg gccagaatca
    53341 tcagctccgg attctttttc acatcctcct cacgcacctc ggtccacctg gaatggggac
    53401 agtaaaagct gtcgtccagg ctccgcacca gcggaacctt acggtttaac acctggtgct
    53461 cataaatgcc tgacagcttc cgctctctcc tgtacttggg aatctggtag tgatagtaaa
    53521 gacccgcctg ggcgccccag cagatatgca gcgtcgaggt tacgtgggtt ttgctccact
    53581 ccataatcgc ggtaagttcc ggccagtaat tgacttcctc gtactccatg ttctccacag
    53641 gcgcccctgt gataatcatt ccgtcaaact ttctcttttt cacctcgtca aaggttacgt
    53701 aaaatttgtt cagatggctg gctgaggtgt tcttcgaatt gtgggacgcc agcattaaaa
    53761 aggtgcagtc tacctgcaga ggcgtgttgg aaagcgcccg gagaagctgc gtctccgtct
    53821 cctccttaat gggcatcaaa ttcaggatca ggatctctaa cggcctgata tcctggctca
    53881 gggccctgtc ctcatccatg gtaaaaatat tttctgattc cagaactgcc ttggccggca
    53941 gatctttctg tactttaatc ggcatatgtg tcctccccgt tagtctgtag ggtatcatac
    54001 catatttcag acgtaattgc cagccgccgc aggaaatctt aggccgtctc tgcagaggaa
    54061 ccggggataa actgtccgat gaattcgtcc tctgtgataa tggggatatt tagctctctt
    54121 gcctttttat tctttgagga agaggaggca gagtcgttgt tgatcagata gcttgtcttg
    54181 gcagttacgc ttcccgtcac ctttcctccc ctctcctcaa tcagctcctg cagctctttt
    54241 ctgtttttaa accgctccac agagccggta atgacgaagg taaggccggc aaggccgctt
    54301 cctgcccctg tctcctcttc ctcctcaggg gccggaggaa gcagaagctc cgccagcagg
    54361 cggtctgtta tcttattatt tttctcattc tggaaaaact ggatccaggc ctctgccaga
    54421 acctccccga ttccgtcgac agccaccagc tcctccttgt ccgcgttcct catggcctga
    54481 aaatcgtatt taaaatggcg gcagagcatt tttgcgttgg ccaggccgat tcccgccact
    54541 ccaagcccgt aaatcactcg gggaagagtg gtgtgggacg ccttcttgac cgcttcgcag
    54601 agcttgtcaa atgatttctt tccgaagccc tccatctcca caatctcggc ttcatgagcg
    54661 tccagatgaa aaatatcggc atactcgtgg atcaatcctc ttccaatgaa cttttccaga
    54721 gtcgcctccg acagacctgc aatgtttaag gcgtcccggc tggcaaacag ggcgaagctc
    54781 ttcagcttct tggcctgaca gtcaggattc gtgcagtaca gcgattttac gtcgttcacc
    54841 tggcgtatct ccgttgcgcc tccgcagaca gggcaggtac atggaatgtt cttcactccg
    54901 cttctggtca ggttgtccgc aatctgggga ataatcatat tggccttata gacggtgatt
    54961 ctgtccccct ctcccagctc cagtgattcc ataatgctta aattatgaac gctggcccgg
    55021 gtcactgtgg ttccttccag ctccaccggc tcaaatactg ccaccgggtt aatcaggcct
    55081 gtcctggacg cgctccactc gatgtaggac agcgttgtct cctggatttc atctgcccac
    55141 ttaaacgcaa tggaatccct gggaaatttc gcagtccgtc ccagcgactg gccgtaagca
    55201 atatcgtcaa acaaaagcac aaggccgtcc gacggcacgt cgtttttctc cacaagcctt
    55261 gaaaatccgg ctaccgcctc ctccaggctg tccgctgtga cccgcctgta ctccacagtc
    55321 tcaaatccct gggactggag ccataaaaac tgtttctccc tggaattttc aaactccacg
    55381 ccctcggcca tcacaaggct gaaggcaaaa aaacggacgt ttctctgagc cgtgatctgg
    55441 ctgttcagct ggcgcaccga cccgctgcac aggtttctgg gatttttgta cctggcgtca
    55501 atctcctcaa tctcctcatt gattttcaaa aaatcggaat agcggatcac cgcctcgcca
    55561 cgcagtacca gctgccccgt atagggaatg gttttcggca cattgacaaa ggttctggcg
    55621 ttggccgtaa tcacctcgcc aatctctccg tttcctctcg taacggcttt cctcagctct
    55681 ccgccctcat aggtcagcac aatcgtcagg ccgtccattt tccaggacaa aagtccttct
    55741 tcgtttccca gccactcctt cagctcctcc acgctctttg tcttgttcag ggagagcatg
    55801 ggcttttcat gacgttcctt cacaagggag ctgactacct cgtagcctac gttctgggtg
    55861 gggctgtttc caaatacggt tttcgtctcc cgctccagtc cggccagctc atcgtaaagc
    55921 cgatcgtact caaaattgct cataatttcc cggctttcct ggtagtaggc ccgtccggcc
    55981 ctgttgagca gctcgatcag ctccttcatc cgttctattt tctgttcctg attcatcctt
    56041 actcctcctg cacctgggct ttctctctgt cctgtctgac gggctctgcc gcccttttta
    56101 cgtttctgcc gctgaaccgc ttcccggcat ccagcggcag aaagatgact ctcctattcc
    56161 agcttcttct tatcctccgt actgtaatcc ttaacaataa acgtattata accgcgggat
    56221 cggagctctt cttccagggc cgccgcatag tccagattca aaaaagcgcc ggccctcaca
    56281 tcgtaatagc cgttgtcgta gaccagaaaa gccggatatc cctgggactg aagctctgca
    56341 agctgctgct cggccaggga acgcaggcgg taggcccctg tctgcaccat atagtagact
    56401 ggcagctccc tcttttcttc ctccctcacc gccttctcca cgccgtctgc aacagcctct
    56461 gcaatcgctt caaactgctg gtcaaacagc tgattatcct ggggattgtc aataaatcct
    56521 gcctcgatca agatggccgg catagccgtc cgcctgagca ccgccagtcc cggcctctcc
    56581 accacgccca gatcctggta acccgttttt tccagctcct catttaccgc ccgggccagc
    56641 ctgccgttta cccccgcgtc ctcatatacc agcgtcataa ttcccgaggc agtccccggt
    56701 attccggctg cgtttctgtg aatggaaata aagtaatcgg ctcccgcgct gtttcccata
    56761 tccgccttct cgtaaggggt gtggtaaacg tcgtccaccc tggtatacat cacgtcaaag
    56821 cctcggtctt ccaaaagatc gcctgctgcc agagccagct ttaaggcgtc gtccttctcc
    56881 tgtcttccga aatagacggc tcccggatcc gtcgttcctc catgtcctgc atctattaca
    56941 actctctttt tcatatttaa aagaaaggct ccttttctag gcatttctat tatattctat
    57001 gaaaaagagc aaaaagagtt ccttctgctt atcctggcta gaacttcaaa tcaatctccc
    57061 cggagaacac ctcctcagcc ggtcctgtca tgtagacggt gtccttttct ctgtcccact
    57121 cgatggtcag gcttcctccc agaagctcca cctccacctt cgtatcggta tagcctgcca
    57181 gaatgctggc caccgcgctg gcgcaggctc ctgttccgca ggccatggtc tccccagatc
    57241 ctctctccca gactctcatt ttaatatgtc ctctgtccac aatctccaca aactctgtgt
    57301 tggttctgtc cgggaagcgg ctgtggtttt caaatttcgg cccaatggtt tccagaggca
    57361 ctgccgccgt attgtccaca aacaggactg catggggatt tcccatggaa attccgataa
    57421 aacggtattc ctctccctcc actgcgatag gctcaaacag ctctgatgtc atttcaggct
    57481 ttcccatatc cacagtcagc tctctggctt ttccgttctc agcctgcacc tttaaggtct
    57541 taatgccgga cgctgtctcc acggtcagag tcgtccgctc cggcggcaca attccatggt
    57601 cataagcgta ttttcccacg catctgactc catttccgca catcgctccc ctggaaccgt
    57661 ccaggttgta catatccatc tggcagtcag ccacagtgga cggtttaatg agaatcagcc
    57721 cgtcggaacc gattccaaaa tggcggtcgc tgacaaatac agccgtcttc cccggatcct
    57781 ctactgtctc ctgaaagcag tccacatata cgtagtcgtt tcctattccc tgcattttcg
    57841 taaatttcat ctctgcgctc ctccctctct tccatattct gcgccgcgtc aagccggtag
    57901 aataaaaaga gggtactctc ctctcagaaa gcaccctcgc tcttgtttaa atataacagc
    57961 gtccgttttg tttgtcaatt tattttgaag gattcgtctc tttgctctgc ctcaggcgtt
    58021 ctaccatctc gcttcccaga gtcatccggc cgatatatcc cacctcgcct gtcatgtaga
    58081 cgattccgtc ctccttgatt tccacctcca gcgtgccgcc aggcatatgg acgtacatgt
    58141 tccgatccgc cagtcccaga cggttggcag cgcaggctgc ggcgcaggcg cagctgccgg
    58201 aagccagcgt gtatccggct cccctctcgt aaatttcaat ctggatattg gtgcggtcca
    58261 gcacgtttaa cagctgggta ttcaccttct ccggaaagct ggaatcacgc tccgaatgtt
    58321 ctccaatccg gcacaccagc tcttttgaaa tctcgttcat ccagatcaca cagtggggat
    58381 tgccgataga aaggcaggtg gtaatatagg gaatctttcc aaacaccatg gtctggttta
    58441 ccatctctct ccgctccccg gtcaccggga tttcgtcgct ccagaaagta ggctttccca
    58501 tggaaatctt cacccgggtg ccctcctcgt tcagatagta taccgtcacc tcgcctccca
    58561 gggtatccca ggaaaccttc gtcttctgga cgtagccggc gtccttcaga tatctggcaa
    58621 aaatccccat gccgtttccg ctcttctccg cctcgcttcc gtctggattc aggattctca
    58681 catacatctt ctcccctccc agcacgggac ctaccagaat tccgtctgag ccgattccaa
    58741 agttccggtc gcagactgcc ttcacctgct ccggtccaag ctccatttca tttttattcg
    58801 gatcatatac cagataatca ttccccatgc aatgatattt ttcaaataca gccttcatag
    58861 aatcctcctc ctgccgactt tttctcatct gtttttattt tatacctcat tttccgcaaa
    58921 taatagaaaa attctgctct tttacttgca tttagcgctc tctttcttct atacttcttc
    58981 tatagcattt tttaactggg agcagagcgg cgggcgcctt aactcccagg ccaaatagaa
    59041 agggcgattt gtatggcttt attgaatgat aagcgggacg aggactgtga aaaacgcggc
    59101 tacctgttcg aggaattccg tttgtttcat ctgagcgatc ctgtgacaga gcctatcggc
    59161 tatcactacc atgattttca taaaatttta ttttttttga ggggagaggc cggatacagc
    59221 gtggaaggcg cttcctatga tctggcgccg ggcgatattg tgctgattcc ccgctactcc
    59281 atccaccggc cggaaatctg tcccggcgcc tcctatgagc gggtcattct ctacctgtct
    59341 cctgaccttc tcaccggaag cctctgtggc ccggaacatc tggccggact gtttcaggca
    59401 gcctcagaca gccgatccta tgtgcttcgt ctgcccaggc tctgccaggc agaacttttg
    59461 gaggccctgt cccggctgga aacgtcctgc cgggaatccg gttttgccga cggccttctg
    59521 cgccggctga ttctcctgga gctgttaatc cttttaaacc gcgcctgcca gtctcctgaa
    59581 tcccgccgcc ttcccgcttc cagcaaaaac gccgcggttc tctccatcat gcagtttatc
    59641 catgacaact cggattctga tttgaccata gacggactgg cctcccgctt ctatatgagc
    59701 cgcgcccaca tgatgcgcct gtttaagagg gaaacagggt ataccatcgg cggttatata
    59761 aacgaaaaaa ggctcctgac ggccagacag ctgctggatc agggcctttc tgtgacagaa
    59821 tgctgctatc gctgcggatt taaaaattat gacgcctttt tgagagccta taagaaatcc
    59881 ttcggagaga cgccaaagcg gaagaagcag ccgtcatccc ttatctctcc ccattgcgga
    59941 acgcgttgag ctctctgatc agaagcttca cattttcgat cagcgaatca aacgctccgt
    60001 atttataaaa gttaataaaa atcagtccga tgggaactgc cagaatcatt ccggcaattc
    60061 ccttaacctt aaagcctagg tacagaagaa acagagtcag cagcggaggc agtcccatgg
    60121 aatctcccac aatcttcggc tgtatcagct gtctggatac ctgggtgact acgtagagga
    60181 ttaaaagtcc cgccgcgtag gtgtactctc ctgtaaacag cttcaccgcg gcccagggaa
    60241 acagggccgt tcccgttcca aacacaggca gaaaatctaa catagaaatc agaactgcca
    60301 gaagcagccc gtacttcacc tttaaaaaca ggaagcccac cgccagaatc ccggccacta
    60361 caaacatgat ccgaaactgg gccagaaaat atcccccgat gactcccctg gcgtccttct
    60421 tcagatactc ggcgtagcgg aggacaaatt tgggagcgta ccgccgcatc cacgctaaaa
    60481 tcttgtcctg ctctgcaata aacagatagg aagagagaat cgtgatgact gtatttacca
    60541 gaacgttcgg gatccccttc gccacgtttc cggcaatctc caccgtaggc gcagccgcct
    60601 tggacaccag atctcccaca taggttccta tattttctgt aaactgcatc actgcagtcc
    60661 gaaactcgtc tggaagaaat tcgaacatcc tgttgccatt ctggacagct ccgcggatct
    60721 ctgccgctgc gctgtcgtac agggcaggca gatctccgat aaattcccgg atttccacat
    60781 aggcctttcc cagtacaaaa tacagaaggc tgataatcag cgccagaaca cctgcgataa
    60841 tcagcatgga tccatgcttt ctcacaatct tcagacgttt ttccagaaag cggaccagag
    60901 ggttggcgat cagggcaatc atccatccaa tgacaaaggg gataaaaaat cccaaaactc
    60961 tggggcccca gacgcacacc agataaagac ctgtcaaagg aatgataata ttaagaatga
    61021 ttctgagata ctttttaaca ccttccatga tgccgcctcc tgaaatctat gccatccgct
    61081 ctgctctgcc tgccgtctct ttccctgcgc ttttgtgttc tctcccgctg ctactcctct
    61141 cctggcaggc cgtactctgc cgccagcttc ttaaattccg gcagcgccct ctcaatctgt
    61201 tcataggata cgcagtaggc aattctcaca tagcccgggc aggcgaagga gcttcccgga
    61261 actacaagga tatggtattt tttcgccctc tcgcagaatt ccttctcatc tcccggcgtt
    61321 ttcataaaca ggtagaaagc gccctccggc ctgatgcact caaaaccaaa gcttttcagc
    61381 ccctcgtaga gcagatttct gttcctgtcg taggcggcca catctgcctt agcgtcgatg
    61441 caccgtttga tcacccgctg catgaaagac ggcgcgttca cgcagcccag cacacggttg
    61501 gcaatcaccg ccgcattgaa cacctgctct gcctcgtcca tctcgtcagg aaccaccaga
    61561 tatccgatcc gctctccagg cagagaaagg gatttgctga aggaatagca gatcaccgta
    61621 tttctataat actttgtcat aaaaggaacc tgtaccccgt cgtaagccag ctccctgtac
    61681 ggctcgtcgg agatcagcac aatgggatgt cctatctggg ctgattttct ctctaaaatt
    61741 tctgctaacg cctgcagagt ttcgctggaa tagacgactc cggttggatt attgggcgta
    61801 ttgataatca ccgcctttgt cttttcgcag atcctctcct caaattccct taaatttggc
    61861 tgaaaggtct ctgtattggg agaaaccacc accagctctc cgtcatagtt tctcacatag
    61921 gatccgtatt ccacaaaata gggggcaaat accatcacct gctcgcccgg gttcagcaga
    61981 gtctttaaaa tcacattcag gccgctggcc gctcccactg tcatcaaaat attgctctgg
    62041 ctgaaggaag tatcgaatct ccggttcaga gactgggcca ccgcctccct gacgtcctca
    62101 tagcccgcat tgctcatgta gccgtggaca aagagagaat cctcctcttc aagaatctct
    62161 ctcattgcct ggtttacctc agctggagcc ggaacgctgg gatttcccag actgaaatcg
    62221 tacacctggt ctgcgccgta cacagcggcc attttcctgc cttcctcaaa catcatacga
    62281 atcgctgaat tattctgaag cagcggctgc attttctctg aaatcatagt attcctccct
    62341 ttttacttta atactgtatc actgtctcca ttccacatag acggccgcgg cccctgtcac
    62401 tgccaggtag aaccaggtgg tggggttgct gaaccaggtg gtgaaaaagg acagtccgaa
    62461 atagacggca atctgggcat acagcagata tccgatggga tttctgatat gcttcaccat
    62521 atcggtcaga taccaggcta acaatcccag aacgcatccc agcaaaacga cgcccagaat
    62581 tccaaaatca tagtaagcgt cataaaacag cgttaccgtg gtcagttcct ccttggtagt
    62641 aaacagcgga aaagctgtca gcgacggaac cagaaattta aggcccgtca gcgcccacag
    62701 cggaaacagc atcttcaggc caaagctgtg gctgtagccg gaggccatgg cccgcaccat
    62761 acagtcgaaa ttgtcgtaat tgtttgcaat atacatatac ggctgtgtga cgaatatggg
    62821 cgtgcggctg tttttcatct caaaaatccc attgagatac tccacgtcat ggcttctggc
    62881 aatcgtcagg ataatgtagg cagccagcag tcccacaaac agtaccgccg cgcttataat
    62941 catctgcagc ggatcaatat gaatatccat catcagatag gtgataacag ccaaaaccgc
    63001 cgccaggatc agctgaaacc gtgaaacgca gagaatggga atcaggactg caattatatc
    63061 cgccccaatc agaattccag tccgcagacg gtcgcgccct ccgttggagt gaaaaaagat
    63121 cacgctcaaa gccggaacca gcacgcagga taccgtaaaa tagtggactc ccgtaatgtg
    63181 gaaataggaa taggcgtgag gcacgcccct taagaaaaac ggcacatagc ctaacaccac
    63241 tgcctccaga acaaagcaaa acagcgacag cgccgtcact gccagcgcgc agataaacac
    63301 cggttcctcg caggaacgga aatcgtgcca ccgcttctgt cctttccatc tggaggcata
    63361 gctgttgtaa ttatttcttc ctctccgctc aaacacctca aacacagcgt aaaagctgac
    63421 aaaggccgcc agaaagcaca gccatgtaag gaaggtccag tcctgtgcca ggcggctcag
    63481 cttcaggcag gaaacgccct gtcctcccac ccaggccaga gcaaagattc cccgcaggtg
    63541 aatgcagttt cctgtccttc tgaaatcctg aacatacaga aagacagccg cccccatcag
    63601 gcagagcccg gaaagataaa aatgctctcc cctggccagc agaaaagagg ccagacagca
    63661 tatcaggtaa acaatcatct tcttttatcc ccatgtatac aaattttgat ccggcgtttc
    63721 cccagacttg ggttttattc ccgctgaaat aaacgccaaa gggccgcata accgcagctg
    63781 tattcctaca gccgcagcta tgcagcgcct ccttaaaagt tcctgctgac aaactctctc
    63841 ataaagctct cgatttctcc ggctgtcgca aagctcatcg ccttgccggc catctcctga
    63901 agttctctgc tgtcgcactc tgtaatcatc tttctggctt tcagcacagc ggaagcgctc
    63961 atgctgaatt cgtttaatcc aaatgccact aaaagcggga tcataagcgg atcgctggct
    64021 gcctcgccgc acatgcctac catgatgccc tcttttcttc cgcattcgat aatatggcgg
    64081 atgcttctga gcacagccgg attaaaggtg gaatacagat aggaaacctt gtcattgccc
    64141 cgatccactg acatggtgta ctgagtcaga tcgttggttc caatactgaa gaagtccact
    64201 tcttttgcaa aaacgtcagc catcagagag gctgcggcag tctccaccat gattcccacc
    64261 tggatattgt gattgtaggc gattcccttc tcgtccagct cctccataat ttcctgaatc
    64321 aaggccttgg cctcacggta ttcctccaca caggtcacca tgggaatcat aatcttaatg
    64381 gctccaaagg cgctggcgcg gagaagggca cgcagctgtg gacggtaaat atcgtccttt
    64441 cggtccaggc agaatcggat ggcacggtag cccaagaatg ggttctcatc cttcttaagg
    64501 cccatgtaag gaatctcctt gtcgcctccg atatccagcg tcctgataat caccggcttt
    64561 ccgtccatgg ctacagccac tttcctgtaa gcctcaaact gctcttcctc tgtcggcatg
    64621 gccgtccgat ccatgaagag gaactctgtc cggaacaggc cgattccctc cgcgtcatag
    64681 gagagcaccc ggtctacgtc ctccgggcgt ccgatattgg ccgctgtctc gatctttacg
    64741 ccgtcctttg taatggtctc ttttccgatg tattttttaa gctcttcctt ttctttcaga
    64801 taaacagcct gtttcgcctc atactctgcc ttcaggctct cgtccggctg aaggaaaatc
    64861 tctcccgtct cgccgtccag tatgatttcg tccccgtcct tcacctgaga gaggattccg
    64921 gaagccgcca caacggcggg aatctccaag gctctggaaa gaattgcgga atgggaagta
    64981 cgtcctccca gctccgtgac aattccagtc acgtttgccg gattaatgcc agctgtcaca
    65041 gaaggcgtca gatcctctga aaccagaacg cttccggccg gaagtgaaga cacgtccaca
    65101 gactgaaccc cgagaaggac tttctgcatc ctcgtcttaa tatcgcgcat atctgccgct
    65161 ctctgctgca tcagctcgtc gtccatggat gcaaacatat ctgcgtacat cgtgcacacg
    65221 tcctccacag ctgcctcgct gcacagcttc tccccgtcga tctttccctc gatctccatc
    65281 gtcatcatcg gatcctgaag gagcattaaa tgaccgttta aaatctctgc ttccttctct
    65341 ccaatcctct gcgccatgtc gtcggccagg gctttcgtat cctcgatgct cttctccact
    65401 gcctttttga aacgcgcttt ctcagcctct gcgtcagcta ttgtctctct ctttatctcc
    65461 agagtctctt ctttcagaat tacaactctt ccaatgccga ttccggcaga cgctcctgtt
    65521 cctgatacca tcttttttcc tccttttata tatgagagct gttactcgcc taaaccgtca
    65581 tttaccgctt tcagcatagc ggacagcgcc tcttcttcat ccttcccctc acatatgaac
    65641 tccagctcat ccccgcattt gatgcaggct cccagaacgc tcaggacact ctttgcattg
    65701 gatacgttat ttttgtgact gaacgtaatc tgagactgat attttaccgc ttcattacaa
    65761 agaatacctg ccggtctcag atgaaggccg ctggtatttt taattgttac ttttgcctta
    65821 accataaact tctcctgtat ccttactttt actgattctg actgccggct gccgccgaag
    65881 acggctcctg cttctgctgg ctgttctctg gaacggcttc cgcagattcc gaggatgccc
    65941 tgacatcctc ctcttgcgtc tcggcttccg tctccggggc cttcgccttt acctccagag
    66001 taatgctggg ggttcctgcc actgtataag cctcgtccag ctgataggaa agagccgccg
    66061 tatgagttcc tggcttcatg cctgaaacgt cagccttcag attcatctta tccggagaca
    66121 gactgttcaa atcctctttc agtcctctca cagtcagagg caccgtgccg tcggccagct
    66181 cgtaggtgta ctcctccgac gcgcccacaa gctcaatatc gttgtcgtca agcgtgtagg
    66241 ttctgttttc taacggctct accttcagag tcactgtcac agaggtgctg tccatgccgg
    66301 ccagctccag tcccggcgga acgaattcct ccagatcaat gacgcactcc ttatcgcctg
    66361 tcagcccctc cgcgctcagc tgaggacttt caatgggaag cgtattcatg ttggccagga
    66421 cagatcggag tcctgccaca gaaacgctgt ccacaccgca ctctacgccg gtcagcctgt
    66481 atccgtcggc cacctggccg gatacctgga aatcaagcgc cagatttttc accttcagca
    66541 tagtcagttc gtaggagata tctcctccta aaactgtcac tgcgctgctg agcgtcagct
    66601 cattgtcatt tgcatcataa aatttaggaa ccgctgttcc tgacagatca ctgtcttttc
    66661 cctctatgtt gatctccact cccacactgc tgatctggcc aatctgggaa acagggcctc
    66721 tcacatacac atagtttgga gtcagcttca cttttccggg caggtaatcc ctatttcccg
    66781 ccgggtctcc tgtcacatgg tgcgtcaggg agaaacgctt cgtctgaagc tcctccgtct
    66841 taatgtggac agttcccgga gcttttacct cgtacttgac gccttccccg ttgctggcca
    66901 gatactgctc atcgtccagc acctccaccg tgacgggaac tgctcctgtc acagaataaa
    66961 gctctgacag atctgcgtaa gccttaaaat cctctgaggt aaaccggtaa atgtccctgg
    67021 ccctggcatt gattagaagc gtcaccgtgc tctttccctc tatctcatag gtcaggttgg
    67081 agctttccag aacctcgtcg ttggtgatat tcacgggaat ctcgatggac tttgtctgga
    67141 tcgggttcgc cacattgacg acagccagcc agaccagaaa agcgcagagc agtgaaatca
    67201 gcttcaacgt agcattttta gtcagctttt ctttcattct tacgccttcc cttccaaatc
    67261 ttaaaccgtc ctgaagaatt ctcctcattc cgcaccgccc gggctaaaat tcctctcagc
    67321 tcgtcggcgt ccgccacgcg gagcagccgt cctccggtcg ccacagatac ccgtcccgtc
    67381 tcctccgata ccaccagtgt caggctgtct gtcacctcgc tgattcctac tgcggcgcgg
    67441 tggcgcgttc ccagcgcctt gctgatatcc atgttgtcag agagaggaag ataacaggta
    67501 gcggctgtca cccggtttcc gcggattacc acagcgccgt cgtgaagagg cgtgttgtgc
    67561 tcgaaaatat tgatcaaaag ctggcttgtg ataattccgt ccacctcgat gccggttctc
    67621 tccacatccg tcaaaggcgt ctccatctcg ataaccataa gagcgcccgt tttcaccttt
    67681 cccatctcga aacaggctct ggtcagctcg ttaatcgtct tctcgctgaa gccttccttc
    67741 acctttccgt cgtcagccgt gaaaattcca gtcagcacgt tcttgctccc cagctgctcc
    67801 agcgcctttc tgagctccgg ctgaaaaatg ataatgagcg ctgtaattgt gatataagac
    67861 gctttcccca gcagccagag gatggtgtcc agttccagta cggcagccat gagaacaaaa
    67921 ccgcagataa acaaaattcc ctttaaaagc gtccaggccc ttgtgttctt aatccagacc
    67981 aggacctcgt acactacaaa ggcaataatt ccaatttcca gaaaattttt gaacgtcatg
    68041 ttcggaacaa acgcaatcca cgaatacagt tcctttacgt attctgccat actctcacct
    68101 cctccttttc ttttttaatt tttctaatct ctccttctgg gagtttttct cgtgttgatc
    68161 cgctggactt tcacgtccgg ctttgacact gcgattttag gaaccgcttt cacataatag
    68221 tggtaatcgt cgtcctcaaa ctgcacgtac tccgtcctgg tgtagtccac tgcaaacaca
    68281 aagaaatggt agacagccgc cgccgccgcg gaaacggcca ttcccgccgt cacctccagc
    68341 acagaaaccg acgcgtcaaa cctcagatct ccgataaaaa tcaccagaag ctgcacgatc
    68401 actcccgccg cgatggcaat tccccaggcg tagttaatcg gcatattctt tatcgtatgc
    68461 accaaaagga tgcagagcgc catagccgct accataatca gcatggcctg attcgtcacg
    68521 agactcttca ccagctggat aatcagctgg gtcagctccg tctgcgcgct tccggacagc
    68581 acgcttgcat tctgcttcac atacagaatc acatagtaaa gaaacgctcc gcagctgacc
    68641 ggaatcacgg acagcatact tcctcccagt cccaccaaaa gcggaactgc aaagggaatc
    68701 ttcagaaaga acatgatcgg ggtcaccaaa agaagcacgc tgtctcccgg ctggaatcca
    68761 taatatagaa gcaccacaat catcagaaag accagcgtga tagccgccac ctccagcgat
    68821 acggcaaaca gctgggccat caggaaggct cccgccagaa acgccgttac gccgtaggga
    68881 actgccgccc ccaccaaccc catcactgca ggcatcagcg aagaattcag cttctccaca
    68941 aagcctgtat tctttcctat taaataaaag gccataaacg ccacagcaaa tttgactgcc
    69001 ggaatcacaa tctggctgtt cttggcgtaa aatatcctca ggcgctcctt gaacacaagc
    69061 agtcccatca tactcttctg tcctcctttg ccagagttct tgagcggtta tggtaatcat
    69121 accgcttgtc aagatgtttc agcttcgccg tataaagcct gatattcttc gccgcataat
    69181 cataccgcct agaatagacc gtatgtacca gtcccatata gacggccagg ccaatcaggt
    69241 aataaatcac aaaattccgg atcaggccca gcattccttc aaaggaaagc gtgcttaaaa
    69301 actgttccat gctgtagaga agccagataa aaagcactgc cgtgcagctg atcgtgtagc
    69361 taaaaaagcc gcggatcatc tggcggctga cgtaatcgct cttaaaataa ttctttccgg
    69421 cgttcatggc ctttccgttt tttttctcaa acatagccat gcttgtcatc agtttgatct
    69481 tatcctcatt gagcatagca ccactccccg attcgaattc gtaaaataaa ttatatcgct
    69541 ttattatagc atacaatcct ttaaatttcg aggggctgtg aaaattttca taaaattgta
    69601 aaaaaagaat cctggccgcc gcccgatgcg gcgcaggact cttttctctc cagcgtcatg
    69661 gcgcgccgtc tctgacgcct gccaaagccg ttttattcat accgcagagc gtcgatagga
    69721 ttggatatgg ccgcttttct agccgggtaa aggccaaaga aaattcccac cacagcagaa
    69781 aaggtgacgg ccagaatcac aacggagggt tttatcaccg cctccacgcc taaagccgct
    69841 ccggccgcca tgacgattcc tccgcctgtt atgattccca ccaggcctcc gcaggctgac
    69901 agaatcgccg actctgtcag aaactgaatc aaaatatcct tcgttctggc tcccagggcc
    69961 tttctgacgc cgatctccct ggtccgctcc gtcacagaaa ccagcataat attcatgatt
    70021 ccaattcctc ctactaccag agaaatagct gcgattccgc ctaccgccac agacagtcca
    70081 gccatcatgg aatctacctg ccccatctgc tccacagcgg actccacata ccagtcctct
    70141 ggatttctgt ttttcagctt ggaaatataa aataccagct catcgtaaaa acgctccagc
    70201 tggctggagg tcatggactc tctcgcaaac aggtggcagt aatagaactc gtcgtttggc
    70261 catgtcagaa ctgtccacgg gatgaaagcg ctgcctttgt cgcttcctcc ccccatcatc
    70321 agctcctgga aggggctcat ctccttctcg tagacgccga ctaccgtaaa ctccttcatt
    70381 tccccataga gaaccgtccg gaaggtccgc ccaaccgggt tatccgtgtg gaaaaaattc
    70441 ctggccgtat caatgtcaat cactgcgtgt tctttcctgc ccttaatatc cgcctcgctc
    70501 agataccgcc cgtaaagcat ctttaccggc tgcacctcgt tataattcca gtcgattcca
    70561 gtgtagttaa actgcatctt atccggtccg gaaacggctt ctgcagaggc gctggcgccg
    70621 ctgtctatat aggcgatatc gtcaccgaat acctccttga tccgcgacag atcgtccatg
    70681 gtaaaataat cgctctccct gacatcgtcg atccagtagc caatccccac ataggtctgc
    70741 gtcaggccca cgtcctgata gaggctggaa aacagctccc tcatggtatc tccgatggag
    70801 acgatggaaa tgaccgaacc gattcctatg ataatgccaa gcatcgttaa aaacgaccgc
    70861 attttgttgg cacgcagggc ggtgaaagcc atcttcatgt tttcaatcag catctgtctt
    70921 cctcccctct ctgcatttcc aggcctcatt tttctcatcg ctgataatct ggccgtcccg
    70981 aaaacggata atcctctggg taaaggaggc gatatcctcc tcatgggtta cgactactac
    71041 ggtggccccc tccctgtgca gctcagaaaa cagctccata atctctatgg aggaggcagt
    71101 gtccagattg cctgtgggct cgtccgccag aatcaggggc ggatcattgg ccagcgctct
    71161 ggcaatggcc accctctgcc gctggcctcc cgacatttcg ttgggcatat gctccgttct
    71221 ggcccccagt cctacccgct ctaaaagctt caccgccctc tcgctgcgct ctctcttggg
    71281 gatgtgggca taggtcatgg gcagctccac gttttccctg gccgtagtcc tggaaatcag
    71341 attaaaggac tgaaacacaa agcctatttt tttatttctt atgagggaaa gctgatcgtc
    71401 gtccatagcg ttaatgtcga ttccatccag gtaataatgg ccgattgccg gccggtccag
    71461 acagcccaaa atattcataa acgtggattt tccggaaccg gactgcccca tgatcgccac
    71521 aaactccccc cgcctgatag tcaggttaat attcctcagt cctatcacct tcatggtccc
    71581 cgtgtcgtag accttgcaga gatttacaat ttttatcagc tcctcacatc cggaatcagg
    71641 gagccccgtc ccaggccttt tttcgcgaat ccggccctca agtctttcta tccatcgctt
    71701 catcataccg gctccacttc cattccctct gtcagtccgt caggagtcag aagcagcgtc
    71761 atcccctccg tcagttcctc gcctatggga ataatttctg tctccagatc gctctccact
    71821 cctgtatcca cagaaacaaa atgcacgatc cctgttcctt ccttcagcac ggcaatctga
    71881 ctgcttccat cctctcccgt tctcacagcg gaagacggaa ccttaaagac gtcctctgcc
    71941 cgctccgtca caatagaggc ccgggccgta attcctgcga tcagcccgct gtcctccttg
    72001 tcaatggaca cagtagccgg cactacccgc tctgtggagg cgcttcccgt tttttcctcc
    72061 cctgtagggg agatcgaggt aatggttccc gtcaccgttt tcccatttaa aatatctgcc
    72121 gtaatatcca cgggaaggcc tactgacaca tcccccaccg aatactcgct gatttgcagc
    72181 tccatctcca gctgggcaag attttcgatg ataaacatgg gcttttcatc ctccggctta
    72241 tctgcaaact gccctacctt ggagttgact ctgacaaccg ttccggaaat ggggcttttc
    72301 acctctgtgt cctccagatc cctctttttc tgatccagct caaactgagc cgccttcacc
    72361 ttaagctcat aggattcgtc cggaactgcc tgtccattct ccatccggta tccctccact
    72421 gcccgtctgg cgtctgaaag cgcattgccc acggcctcaa actccgcgga ggagatcgcg
    72481 ccggcttcaa acaaggtttt gtttcgctca tagttcaggc tggctgtgct gtaatcctgt
    72541 tttgccttct catagccaat tttcgtgtct ctgaggcttt cattatactc gctgaccgcc
    72601 agatcgtaag cgttctgggc gacgtccacc tccttttggg cgtccgtcct gtcaattacc
    72661 gccagaacct gccctttctc caccgtatcg ccctccttca ccctgatttc caaaacctct
    72721 gaatgaaggt tggaaaccac gtccgcgctg tctgttccgg aaaccggacc tgtcagagag
    72781 agactggaca ctacgtcgcc cttcgcaagg gccatggacg gaacctggga cagcgtgctg
    72841 cccccggctg tgtaccggac agccaggcat acggccgccg ccacggccag cacggcctct
    72901 atgcgcttct ttttgggaga ctgtcccctg attgccctga ctgcaccgga cagagaaaga
    72961 cggcggcgct ttccattctt tggctcattg atgtacgcct ccagttcccg ctctacctct
    73021 tccccgctct ttggagaggc atacgaagta tttttatgtt cttccataca acatcctgac
    73081 ctttctcaat ttcacagatg tggggcatct gcccttctct tctgtcttca atttcccttc
    73141 tgtgttctta aacgagtcag gctcctccct gtcttcacaa aacagaaatt ttatactcct
    73201 gttttcgcac agatgtcaga caggcagcag cgctcacaat ggggctttgt tctggcagtg
    73261 catacatccc gtccatggta aacgagacga tggcagaaat cgcttccctc ctccggcgga
    73321 accagcttcc acaaaaccat ctccactttt ttcggctcct taatcccttc cacaatacca
    73381 atcctgttta ccagacggat gcagtgggta tctgttacca tggcaggctt tccgaacaca
    73441 tctcccataa tcagattcgc gctttttctg cccacgcccg gcagggataa aagagcgtcg
    73501 aaatcgtccg gcactctgct gtcaaactga tctctcagca ttttcataca tgcgctgatg
    73561 tccttggcct tgctccgccc caggccgcag ggctttacaa tggcctctat ctcctccacc
    73621 ggcgcattgg ctaacgcgtc cacatccggg aatttcgcgt acagatcctt taccactacg
    73681 ttcactctgg cgtccgtaca ctgggctgcc aggcggacgc tgactaacag tttccaggcg
    73741 tcgttgtaat ccagcgtgca gacagccagc gggtactcct ttttcagccg cgcaatcact
    73801 tccagcgtaa gttcttcttt tgtcatacga ttttcctcct ctgtcgtctt cctgttttgt
    73861 cttgttttgt tattgtacga taaacaaggc ggattgtaac tatatttttc cggatttccc
    73921 taggaatttt caaggaagtc tgttagaata gacctcgttc ccgttaataa accgtaaaat
    73981 ttttcagttt aactaaaaaa tacggaattt tcacaggagg attaagagta tggaacactt
    74041 tttcaagctc aaagagcatg gaaccgacgt ccgcacagaa atcattgccg gcgtaactac
    74101 ctttatgact atggcctaca ttttagcagt caatcctgct atgctggggc cagacggcgc
    74161 ggggatggat tcaggcgccg tatttacagc taccgccctg gcgtcggctg ccgcttcctt
    74221 tttaatggca tttctggcca accttccctt cgtgctgtct gccggaatgg gattaaacgc
    74281 ctattttgcc tatacggtat gcggcagtat gggatacagc tgggaggtag cgttaaccgc
    74341 tgtatttgta gagggtatta tcttcattct tctctccctg acacgggtaa gagaagctct
    74401 cttcaacgcc attcctgcca cgttaaaaat cgccgtagct gtgggaatcg gccttttcat
    74461 tacctttatc ggtcttcaga acgcacatat tgtagtggct tcctctacac ttgtcagtct
    74521 gttttccttc cggggctcta tgacagccgg aaccttctcc tcagaaggca ttaccgtgct
    74581 tctggccctt atcggcatta ttattacttc cgtgctcctc atcaagaggg taaagggaaa
    74641 tatcctgatt ggtattctgg ccacctgggg acttggaatg atctgccagg ccgtgggact
    74701 ttacgttcca aatcctgaaa tgggatttta cagcctcttc ccaagcggca tcatttccat
    74761 gcctgcttcc gtagtgccca cttttatgaa aatggatttt tctattgtgg gaaccctgaa
    74821 ctttgcagta gtcattttcg cgttcctctt tgtagatatg ttcgacactc tgggaacctt
    74881 aatcggctgt gcttccaagg cagatatgct ggatgaaaac ggcaagcttc caaaaatcag
    74941 aagcgccctg tttgcagacg cagtaggaac gacgcttgga gccgccctgg gaacctccac
    75001 tatcacaacc ttcgtggagt cttcctccgg tatcgcagaa ggcggaagaa caggacttac
    75061 ctccgtgaca gccggtattc tgttccttgt atccctcttt ttatcaccgg tatttttagc
    75121 catcccatcc ttcgctaccg ctccggcgct gatcgtagta ggatttctga tgatgcagca
    75181 ggttgtaaaa attcagtggg ataacctgac agaggctatt ccagccttta tcgctgtcat
    75241 cgcaatgccc tttatgtatt ccatttctga aggaatctcc atgggcgtta tctcctatgt
    75301 gctgctccac ctgctcacag gaaaggcaaa ggacaacacg cctctgatgt atattctgac
    75361 tgtgctgttc attttaaaat acatattcct gtaatcgctg tataaatgta taaaaaagag
    75421 aacggttccc tgcttcatct gaaagctgcc ggaaaagttc tcttttttct gccgccgctg
    75481 cggtattacg gtatttcttt tctttctctt gaattagctg aaaaatgtgc tatactggta
    75541 gtatgcagat atggttcatc ggtagaacgc cagcttccca agctggaaag gcgggttcga
    75601 ctcccgttat ctgcttattt ttatgccctt gtatttgctg gggaaatagc agttttcctt
    75661 gtaaatacaa ggattctctt ttttgatgta agtatttaat atcgccgtat gataggaaaa
    75721 cattaccgtt tttaactcaa atatcacacg aaatatcaca cgaattttgc accgattttc
    75781 tttatttgtc aatgctttgc agtaatttaa aaagaacaat atcacacaaa accgaagatg
    75841 atacaatcag ggcggccaga tggccgcctt tttaaatcac ttctccgtct tcctggatcc
    75901 ggctggatgt cagcatccag ccgttaaaat caaagcagta acatctgccg ttgatgactt
    75961 ccaggcggcc tgctggatag atataacctg ggcgcagata ccaccatctt ccgtcctctc
    76021 ggatccagcc ctggaggtaa tcggcgctga tccagcccct ctccgtcagg aaccatcgtt
    76081 ctgagcctgc cagagccttt ctgagcggtt ttattcggtt ccccttatag tatcttcctc
    76141 cggtatcttt accgcctggt gcgtcacgga tgaccaggga ggaggccgtg acctccactt
    76201 gcgctgtgtc ggtgctgatg gtctggtatt cccacatagt ctcctcgcct gttatggccg
    76261 ccttgaaaac gtcccaggtg tgagatgtat gattatatac gtaagggttc gggcaaatct
    76321 tgccggttac gtcgtaatga cgaatcacat ggtctgccgg aatactatat ttctccatca
    76381 gctccctcgt cagttcaata gccgcctgaa cggtagcatc ttcgaagtac cagtcccggc
    76441 tgtctgctgc ctggcttcct ttattcctga cacacagctc aataccgata ctgttggaat
    76501 tccgacattc cggatgcctg taactttttg ccccacagtg ccaggcaatg tctccatcct
    76561 ctacgctctg ccagatttcc ccgccaaatc ccacatagta gtgggcgctg gctccgatat
    76621 atttgctggc ataataccgg cagttggcct ccgccccgcc ggtagctccg acgtagtgga
    76681 tcacgatgta cctgatgcgg ttggtgtcac ccagacgatt aaggttgtac ggcgtcagca
    76741 gtttgttaat ctgcatcgtc aatcccctcc tttccgtccg ggcccatcgc atctggatcg
    76801 atggctgcct ggaagtcctg cagtgctgtt tccgatgctt ccctggcctc cttctgaagc
    76861 tctgtaaacc acttatcgcc aagatctgct ctctgcatac tctttaccat ataggctcct
    76921 ttccgggagg cccgaaggcc tcccccccct gttgcgacgt cggaactatt ttcccgggcc
    76981 aatcggcgtg ttgccgccgc ctaatccagg gccaaccggc gtattgccta atccctccag
    77041 gccaggtcct actggtgtgt ttcccttacc ctctgctgcg gggcctgtag ctccaacgtc
    77101 acaagtacag tctgcaatcg gctcagggat gtgggttcct gccttctcct ggtcaaatcc
    77161 gttctctccg tgtactgggc atttgtgtgt tctactcata gtttgagtcc tccttaaaaa
    77221 atatttttgt ataaaaagaa cgtccctgat taaaaggacg ctctaattat cagcaag
//
LOCUS       DBMDUW010000005        71339 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_423_length_71339_cov_4.938207, whole genome shotgun sequence.
ACCESSION   DBMDUW010000005 DBMDUW010000000
VERSION     DBMDUW010000005.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 71339)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 71339)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71339
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_423_length_71339_cov_4.938207"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(505..2166)
                     /locus_tag="ACZPCR_01920"
     CDS             complement(505..2166)
                     /locus_tag="ACZPCR_01920"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008399129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003724 - RNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0000027 - ribosomal large subunit assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HIR1229680.1"
                     /translation="METIRFDELNLDAKILRAVTDMGFEAASPIQAKAIPLEIEGKDI
                     IGQAQTGTGKTAAFGIPLLQKIDPKNKKLQAVVLCPTRELAIQVADEIRSLAKYMHGI
                     KVLPIYGGQEIVKQIRSLKDGVQVIIGTPGRVMDHMRRKTIKFGQVHTVVLDEADEML
                     NMGFLEDMETILSELPEERQTVMFSATMPAAIAEIAKKFQKEPEIVKVVKKDLTVPKV
                     TQYYYEVKPKNKIEVMCRLLDMYAPKLSVVFCNTKRQVDELVLALQGRGYFAEGLHGD
                     LKQVQRDRVMNGFRKGRTDILVATDVAARGIDVDDVEAVFNYDIPQDEEYYVHRIGRT
                     GRAGREGKAFSLVVGKEVYKLRDIQRYCKTKIVPQPIPSIDDVTEIKADKILCQAEEL
                     LQDSDMNRLIDIIEKKVLEEDYTTLDLAAGLLRMIMGEDNEDIIEDSRPLRSLDDLGD
                     YRDRNSGRGRGGRSGGRGGRSGGDDMARLFINIGKNQNVKPGDILGAIAGESGMPGKM
                     VGSIDMYDKYTFVEVPREQADVVLQAMKDVRIKGKNIHMEKANRK"
     gene            complement(2430..3737)
                     /gene="brnQ"
                     /locus_tag="ACZPCR_01925"
     CDS             complement(2430..3737)
                     /gene="brnQ"
                     /locus_tag="ACZPCR_01925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007716856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HIR1229681.1"
                     /translation="MNETLKGRRLLIVGLTLFSMFFGAGNLIFPPFLAAQAGTAAWPA
                     MAGFLMSAVGLPVLGVIAVSRAGGLDCLAGKVHPAFSMVFTILIYLSIGPCLAIPRTA
                     STSFEMTVLPFLNDGAQTAFWQLIYSAVFFLLAAVTAFHPEKLTQRLGKILCPALLGL
                     IFIMFAGSIAAEPKALPMPAEAYSGLAPVKGFLEGYQTMDTIAALNFGIIIAINIRAV
                     GVEDKDAVVTSTVRSGLIAGALLASVYCALTYVGIKAGPEAQTLDNGARVLTFVAERI
                     FGSAGTVVLGLIFFIACFNTCVGLLSCCSEFFCQLIPRISYRKWVVLFAAVSMAVSNA
                     GLTKILAFSVPVLNGIYPVAIALIFLSFAGKGGRAMYRLTVLLTGAVSIVYALEGAGI
                     SVPVLSQLFALLPGYGLGLGWLLPGLIGALAGKGLDAAAGERK"
     gene            complement(3734..5431)
                     /locus_tag="ACZPCR_01930"
     CDS             complement(3734..5431)
                     /locus_tag="ACZPCR_01930"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024629.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 39 protein"
                     /protein_id="HIR1229682.1"
                     /translation="MIWETIREGGSNEGAEGRAKDGIPGLAKGEAGRGRSRRREQGEE
                     RSCLESAACILILLIFTGILLLLLYLSITGSAAVYGGAEQVWFYKDSPLYHLLVFMLV
                     TALGVMILKVRNAEGREEKSREEQEERRKRFVRLLLILSGFYVIWIMGTMFRPASDQR
                     LVIDCGKALAAGDLLPWNQVGFRYHYDEFEGYAYTYPHQNGQILFAAFLSLLAGEQAA
                     FLWQLLNVACLAAGILYTGKMAEEVLEMKNGFYGLALLMMAFLPFSFYVTFAYGTLPG
                     FACSAAAVWYERRFLEERRKRDLILSSVLISAAILFKSNYMIVLTAMVLFFIAEAVFR
                     KKLFPLLGTAAVLSAYLLSHSLVLGGLSLAAGHSVEGGPPMLTWAEMGLQEGSRAPGW
                     FNNYNVHIYLDNREDRELTAAAVERDLGRTIQYFMEHPDYAADFFNRKLRSIWTEPTF
                     QSLWIQEVKGFGWLFPSFTRSLFKEGGTANEIYWQLCNAVQTLVYAGALLFAVFRFRR
                     VKFQGLFFAVIFIGGFLFHLFWEAKGQYTVSYFTLLIPYAVLGMQDWIHWVSKGRFV"
     gene            complement(5485..6174)
                     /locus_tag="ACZPCR_01935"
     CDS             complement(5485..6174)
                     /locus_tag="ACZPCR_01935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007867519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIR1229683.1"
                     /translation="MSRILIVEDEEAIAELEKDYLELSGFGVEIENNGETGLKRALEE
                     EFDLLILDLMLPGVDGFEICRKVREVKNTPIIMVSAKKDDIDKIRGLGLGADDYITKP
                     FSPSEMVARVKAHMARYERLIGSGMPENEIIEIRGLKIDKTARRVYVNGEEKNFTTKE
                     FDLLAFLAQNPNHVFTKEELFSRIWDMESLGDIATVTVHIKKIREKIEFNTAKPQYIE
                     TIWGVGYRFKV"
     gene            complement(6171..7661)
                     /locus_tag="ACZPCR_01940"
     CDS             complement(6171..7661)
                     /locus_tag="ACZPCR_01940"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1229684.1"
                     /translation="MKIKTRLAIAFITITVVPIFLIYGAITALSNYQIRSFQKTYGLS
                     EQVDLLSGNSMQVFNRLTINSQKKIRDIAMNEPDRLEDPEYLAKVNEALREEYSFLLV
                     RKGPDIIFSGDPEGEKLSSQLPPYGEDNSDVLSGGFYVDGEEQHLLKQIDFQYDDRSR
                     GSAFIVTNVGEYVPEIKSMLNEMLIVGIAIICLTGGMLVMWVYRSILRPLHELQEATK
                     KIRDGNLDFTLDAENDDEIGMLCQDFEEMRLRLKESAEEKIQYDKESKELISNISHDL
                     KTPITAIKGYVEGIQDGVASSPEKLDKYIRTIYNKANDMDRLIDELTFYSKIDTNRIP
                     YTFSKINVAEYFWDCVEEVGLDMETRGIELGYFNYVDEDVLVIADAEQMKRVINNIIG
                     NSLKYLDKKKGIINLRITDDGDFIQVVIEDNGKGIAAKDLPYIFDRFYRTDSSRNSSK
                     GGSGIGLSIVKKIIEDHGGRIWASSKEGIGTEIHFVLRKYQEVIQE"
     gene            complement(7820..8245)
                     /locus_tag="ACZPCR_01945"
     CDS             complement(7820..8245)
                     /locus_tag="ACZPCR_01945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008399112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HIR1229685.1"
                     /translation="MEQNVCKNPSPGEPVTSEAESGQKESAGAYIVARALCYIKGNYR
                     KHLTLAGVAEQIFVSRWHLSKLLNRHTGKNFSELLNQVRIDEALRLLKDPTRRVGDIA
                     VEVGFSDRAHFCHVFKRQVGISAGEYRIRLGQETAGGKG"
     gene            complement(8556..9746)
                     /gene="metK"
                     /locus_tag="ACZPCR_01950"
     CDS             complement(8556..9746)
                     /gene="metK"
                     /locus_tag="ACZPCR_01950"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018595377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HIR1229686.1"
                     /translation="MEKLLFTSESVTEGHPDKMCDQISDAILDALMEKDPMSRVACET
                     AVTTGLVLVMGEITTNAYVDIQKIVRETVREIGYDRAKYGFDCDTCGVLTAIDEQSAD
                     IALGVDKALEAKENKMSDEEIDAIGAGDQGMMFGFAANETEEYMPYPISLAHKLARRL
                     TEVRKNGTLPYLRPDGKTQVTVEYDENGKPFRLDAVVLSTQHDEKVPQEQIHKDIKRY
                     VFDPILPAHMIDTNTKFFINPTGRFVIGGPHGDSGLTGRKIIVDTYGGYARHGGGAFS
                     GKDCTKVDRSAAYAARYVAKNIVAAGLADKCEIQLSYAIGVAHPTSIMVDTFGTGKLS
                     DEKLVELVRENFDLRPAGIIKMLDLRRPIYKQTAAYGHFGRNDLDLPWEKLDRVDTLK
                     AYLK"
     regulatory      complement(9940..10057)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(10162..11454)
                     /locus_tag="ACZPCR_01955"
     CDS             complement(10162..11454)
                     /locus_tag="ACZPCR_01955"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007862585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HIR1229687.1"
                     /translation="MEQYIMKGGNPLVGEVTISGAKNAALGILAASIMTDEEVLIENL
                     PDVRDINVLLEAIEEIGAKVDRIDRHTARINAKHIKEVSVDDEYIRKIRASYYFIGAL
                     LGKYKSAEVPLPGGCNIGSRPIDQHIKGFRALGAEVEVKRGAVVAHAIDLVGSHIYLD
                     VVSVGATINVMMAATLAEGETIIENAAKEPHVVDVANFLNSMGANVKGAGTDIIRIKG
                     VRKLHGTEYSIIPDQIEAGTFMCAAAITRGDIMVQNVIPKHLEAITAKLIEMGCEVTE
                     FDEAVRVVGKPRQKHMDIKTLPYPGFPTDMQPQITVTLALAEGTSVVTESIFENRFKY
                     VDELSRMGCSIKVEGNVAIIDGVKGFTGATVNAPDLRAGAALVIAGLAAEGYTVVDEI
                     GYIQRGYENFEEKLRGLGAVIEKVDSEKEAQKFRLKVG"
     gene            complement(11630..14152)
                     /locus_tag="ACZPCR_01960"
     CDS             complement(11630..14152)
                     /locus_tag="ACZPCR_01960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008399106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229688.1"
                     /translation="MKKISKKVWMIMMAVIAAAALSAAAVTAFKDKKQENAAYTPIED
                     GNIPVAYMEMGGRQMNRLHGFLGDRREWADRGNLTVLPKDRKLTVDFYNLDSRITGIQ
                     YEIRSMEDESLIERTVVKDWHQDEGAAEAVTILPIQNLIDKEEEYILTLAIATENQPE
                     IYYYTRIVWTDDAYLEPMIQMAETFSDNTFHYEKASDLTTYLETDPAADNSSLGRVTL
                     KNSFDQMTWGNLSLEKTGDMEMELKELQGNMATLCLSYVAATAGEQGEDSGETQEEQD
                     REYYDITESFTMKWSSQRIYMMDYERTMNQIFDGGSEQYSGKRIMLGISDSHGLQELR
                     SPNGEYQAFVVNRELWMYSRADSQSTRVFSFRQSETDEMANLQDYGIKLLSAGDDGTV
                     DFLVSGYMSRGSHEGGVGVSLWRYEKGTNTLTERLYLPANESSEELLMGMDTLSCLSS
                     SGTLYLLMGNTVYSVDTASRQAQVLAEGMTEENFAVSPGQERIAWQDGEDLYDSRSVH
                     IMDLETGKSAQIKAPEGSSIRLLGFVGGDLVYGLAEENSSVKVNGRTVQAPMYALEIV
                     GKDMNLQTRYEKEGVYITDVEIEGSRVHLQRMTRVGDSYMTAGADTLVCNEEVEEDSM
                     EGIGYLASEEQGRVYFVQTAESVSGGVDLNVPSKAVAEENNTVVLGQPEPSGRRQYYA
                     YSGGRLRGVFESFPDAVTAAYDGMGIVTDEDGSVFWSRVDRADMITIRNPESLVPDLE
                     RYLKGFEEGDEETSDGGAIIDAGGLSLNQILYFISRGYPVAAYTGDGSYAVIYGYDAY
                     NISCLWYPGTEQAYTDKMGLNDAASWFEANGGNGFVAFLFED"
     gene            complement(14239..14895)
                     /locus_tag="ACZPCR_01965"
     CDS             complement(14239..14895)
                     /locus_tag="ACZPCR_01965"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229689.1"
                     /translation="MQDFLDTDSPSAGPPKTGLSETIRDFEYFSMLCPGKLRGIQAEV
                     KAVCDRLDYQGSPIYDEYPDRVAMEQLSRGIARRVSERLSEEENTALYTAEVCSYSGT
                     VITGNPAPRVRAMETAVPGEAMETGEEGDTESLHMEDVNGRGGPKGPGPARRPWGPPP
                     PPNHPWGPPPPPPNHPWGPPLPPPNHPGGHGNPDWGDIAALLLFSEIQRRRCQSRGCR
                     "
     gene            complement(14956..15894)
                     /locus_tag="ACZPCR_01970"
     CDS             complement(14956..15894)
                     /locus_tag="ACZPCR_01970"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003505916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HIR1229690.1"
                     /translation="MKQTSLVIMAAGIGSRFGGGIKQLEPVGPGGEIIMDYSIHDALE
                     AGFNDIIFIIRKDLEKDFKEIIGKRIEKIAPVSYAFQELSDLPEGYSVPEGRKKPWGT
                     GQAVLSAKGLIKHPFLVINADDYYGKEAFRTIHDYLVDVMDTEREGEPYDICMAGFIL
                     ANTLSENGGVTRGVCQVGQDGILKSVTETYQIEKKGEELSAFDKEGNPVSVSGEQHVS
                     MNMWGLTPSFVKALEAGFPEFLKGPGAQDLKAEYLLPTIIDQMIRRGQAKVAVLETKD
                     KWFGVTYKEDKEAVSQAIRELCRQGVYEDCLFQAGR"
     gene            16126..16653
                     /locus_tag="ACZPCR_01975"
     CDS             16126..16653
                     /locus_tag="ACZPCR_01975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgjV family protein"
                     /protein_id="HIR1229691.1"
                     /translation="MTAKYFVIQCIGFAGTLLFFFSYQCKSNRNLFRIQFLSYFIYTI
                     HLILLGAMTGGISYIINTFRSFCLGGKWKSAKSWGMCAVICFLQIITLVLTWSGWISI
                     LPVAANIASTIAGYSHNPRKIRLAGMFINSPLWIVYNAMSGSLAGILDEVVTELSMII
                     SIFRFGWKSLDRVEE"
     gene            complement(16665..18740)
                     /locus_tag="ACZPCR_01980"
     CDS             complement(16665..18740)
                     /locus_tag="ACZPCR_01980"
                     /EC_number="2.7.7.65"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: protein motif:HMM:NF012772.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA];
                     GO_function: GO:0071111 - cyclic-guanylate-specific
                     phosphodiesterase activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HIR1229692.1"
                     /translation="MKILKEGKGLIHLEEERKIYMRTIQFLDESTDDYLYLYDLINKK
                     LYFTDKICEKYSIPSGMEGIPIESWIRIVYPKDQKKLEESLNDIQIGCSENHDMEYRL
                     MNWEGKKVWIYCRGTVLKDRTGLPVFLMGSISEQAMRHKIDALTGFWNFEKFSEDMRK
                     SLKEKNGYFMSLGIDNFRDINVKNGRSFGNRLLKKIADLLENYADEDMILYRLDGDQF
                     AVDFVEKTEKDVRAFYQRVKEELTSFCTLSAGVVAYTRGDNLERGNIYQYADNALERA
                     KREGKNKMLFFSEKTYQKRLDKIELQDELREAVMKNYQGFYLCYQPQISGSRFEIYGA
                     EALLRFESPSRGIVSPAEFIPLLEQSRLICQVGEWAFREAARQCVKWRKKKPDFHINV
                     NISYVQLRQDDIALKAIEILRDTGLPGSALTLEVTESMQLQDYSYFNKIFYEWKRHGI
                     KIAIDDFGTGYSSLSYLKSIDIDEIKIDRCFVSRIQYNAYNYRLLSNMIELAHNAQIQ
                     VCCEGVETEEELAALQELRTDILQGFLFAKPYRAEEIEKIYFEEESEEYQFRIKKEDK
                     FRQLNSKESTAMLQELCKDEIVNIVESMDEIIYVSDMDTRELYYMNTAGRKMTGIYNY
                     KGQKCYKVLQGRDKPCEDCLCRKLDRKGFQVWERNSEFLKQHFIVKGKLIPWFGKMAR
                     LEIAAVKEE"
     gene            19047..19283
                     /locus_tag="ACZPCR_01985"
     CDS             19047..19283
                     /locus_tag="ACZPCR_01985"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229693.1"
                     /translation="MKRKRFSRVDWQVSLLLSILLVLFGISIFLTSSHICYYSILDSL
                     THRVENMHNYVEHELTPEAFWEINTKEDMNKKSY"
     gene            19380..20216
                     /locus_tag="ACZPCR_01990"
     CDS             19380..20216
                     /locus_tag="ACZPCR_01990"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: protein motif:HMM:TIGR00254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HIR1229694.1"
                     /translation="MDGLSESAADFRYPGDLIEPEIQQELHEALSGKTVLPDKILDTG
                     WGNIFIAYSPLHNGQGKVVGALGIEIAADVEAAAIDQLSKAIFVSCLFFCGISIFISL
                     VIFRRISNPLYRDMSNTDFMTNLKNRNAYEVDRDNWTSQKTLSQLTVVVVDLNNLKLA
                     NDQLGHDVGDACIIHAAKILHKLENRKTTAYRYGGDEFILLMEDQPDPMPLLLKAKKE
                     FCKYGSELKIPVALAIGVAQFDKSRDHTIADTQKRADEQMYQDKLEIKAYERQNIDSC
                     FS"
     gene            complement(20318..20620)
                     /locus_tag="ACZPCR_01995"
     CDS             complement(20318..20620)
                     /locus_tag="ACZPCR_01995"
                     /EC_number="1.8.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008705666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HIR1229695.1"
                     /translation="MEKILTAENFETELVGAEGAMLVDFWAPWCAPCRMQLPIVKQMA
                     EDGYRVGTVNVSEQMELAGRLGVMNIPTLIVFKDGKEYQRFVGLQSRQTLEYAMER"
     gene            20994..21299
                     /locus_tag="ACZPCR_02000"
     CDS             20994..21299
                     /locus_tag="ACZPCR_02000"
                     /inference="COORDINATES: protein motif:HMM:NF015567.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HIR1229696.1"
                     /translation="MVFIKNEVKQEQTFPKILVLTHGFFGSELIKSAELVIGKMENTE
                     FIPLTSDISVTAYQEKVFSRLTQLNENDIVLVDLLGGTPSNTVALFSKQKKFPLLQV"
     gene            21425..22459
                     /locus_tag="ACZPCR_02005"
     CDS             21425..22459
                     /locus_tag="ACZPCR_02005"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF028222.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase"
                     /protein_id="HIR1229697.1"
                     /translation="MEYKTLVMNGVKQLELRTHTLPVPEAGQILIRVKSCNICTTDWQ
                     NWNGMRGERSKHFPYAPGHEASGIIEMVGPEVEGYKPGDHVSVGFTECGYCSDCRSGN
                     TKNCKNTSEIHPLPGVTGGFGMAEYMLLFKHQVFKMEDSLPFEEASYLEPLATAVHGI
                     RKMNVQPDDTMLVIGAGNMRMLNAQVARAFGCRVFISEVNENRIRVASSLGFDVVNPA
                     KEDITAFADRFSFHQGVDHVVMAVGNQPAVDQAFSLVRRGGKVLFFAAGYPSPSLDLD
                     VNKIHYGNWHLIGTGGANVGDYCLASQYLNHGTVKTAQLISHRVPLEDYEKAFELAET
                     PGNYRVSLMP"
     gene            22478..22954
                     /locus_tag="ACZPCR_02010"
     CDS             22478..22954
                     /locus_tag="ACZPCR_02010"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF015769.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HIR1229698.1"
                     /translation="MNEIILSRVDSRLIHGQVMTMWSKTGGINHIYVVDDQVASDPFM
                     KDVYLMAVPDSLGVTIHSVDDAVSQYKNGQMPDAKLLVLIKDVTTAYRLWKQRFPMES
                     LQIGNLTPQKKTKILHRSSRLSEEHMPELLEMRREGVMVYAQSVPTEKKIDVETWA"
     gene            22973..23728
                     /locus_tag="ACZPCR_02015"
     CDS             22973..23728
                     /locus_tag="ACZPCR_02015"
                     /inference="COORDINATES: protein motif:HMM:NF015566.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HIR1229699.1"
                     /translation="MFLQSLLIGILYFFCRWNPFYTSWLEASCTPMFLSVIIGFIMGD
                     VTSAVIVGAYVQTVYLGLITGLGGVATVDKSLGSCIIIPLAVASGMSPELAVSMAIPF
                     GLLGTLTINLSKVFSSFAASRCDKAAEEGNAAKFRRIHLGYAAGFWSIFGIIPVTLIN
                     YFGPSAVTSVVNAIPERLVTGLTVAGGLMPALGFAMTVRVIGRKNYLPFFFLGFFLVK
                     YFNLPSIGCAIFAVIASIIYIQLKGGKANEQTA"
     gene            23712..24548
                     /locus_tag="ACZPCR_02020"
                     /pseudo
     CDS             23712..24548
                     /locus_tag="ACZPCR_02020"
                     /inference="COORDINATES: protein motif:HMM:NF015570.6"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
     gene            24613..25185
                     /locus_tag="ACZPCR_02025"
     CDS             24613..25185
                     /locus_tag="ACZPCR_02025"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: protein motif:HMM:NF013296.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0030388 - fructose 1,6-bisphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HIR1229700.1"
                     /translation="MLIDMKTLLDEATKKGYCVPAPSVFNALTIETAFSRAVKVHSPV
                     ILNAGGPLDFEFLAETAKFYSRRNPEVPVALNLDHGDDFEQAMRAIRAGFTSVMLDKS
                     SAPFEENIRETKEVVHAAHIVGVSVEAELGCVGFGRLSDAAKGNIIDFLSDHDPHQRG
                     VYGKMPTAGMQGYGDKLEEYMILFGSAGQW"
     gene            25224..26225
                     /locus_tag="ACZPCR_02030"
     CDS             25224..26225
                     /locus_tag="ACZPCR_02030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004461993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HIR1229701.1"
                     /translation="MEYTYLGRTGLKISRLCLGTMNFGPRTEEKDAFRILDMALDAGI
                     NYIDTANIYGSLHGTHENNHTGWTEEILGRWFAQGGQRRERVILATKVYCNMKDPAEG
                     PNGDGNSAYKISRHIDGSLKRLQTDHIDIYQMHHIERHAPWAEIWPAFERLANQGKIL
                     YTGSCNFAARHLVTAQYEAKKRNFLGLVSEQDKYNLVNRLPELEVLPAAKELGIAFLP
                     WSPLHGGYLSGTMMNRHAGSRGSEEFAAHLSEAQKQQLLQYESLCTDIGESQADVALA
                     WLLRNPGVTAPIIGPRTDRQLESALHAAEIKLSDDVLKELDRIFPGPGGEAPEAYAW"
     gene            26329..27486
                     /locus_tag="ACZPCR_02035"
     CDS             26329..27486
                     /locus_tag="ACZPCR_02035"
                     /inference="COORDINATES: protein motif:HMM:NF012385.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HIR1229702.1"
                     /translation="MKEIILDYVKNVTKEKDLDYLFKNLNSQYIADKFKIKRNTVSQY
                     LNEAASKDLVKINTRPVLFLHREEFIKRFFYLSKQSYSSIQELLSEENQNIQIHEDIF
                     QNIVGYNGSLKRPIEQMSSSILYPDNSLPILLHGPSGSGKSYLAGLMHQFAIHNHILA
                     PDAPFHIFNCAQYANNPELLSSNLFGHSKGAFTGAVCDTKGILAASDGGILFLDEVHR
                     LNFENQEKLFIFLDKGIFRKVGENAVWQKANVRIIMATTEDIHSSFLDTFIRRIPVIV
                     TLPSLEDRGKEEKLQLLSLFFYRESKVLKKRVLISRQVISLLLSSAFKGNAGGLLSVV
                     KYTCAKAYSHSRSNECICVKISDLPEPVIASASFEHGSETDFQENRIIHRN"
     gene            27437..28447
                     /locus_tag="ACZPCR_02040"
     CDS             27437..28447
                     /locus_tag="ACZPCR_02040"
                     /inference="COORDINATES: protein motif:HMM:NF013070.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HIR1229703.1"
                     /translation="MAAKLIFKKIELFTGIDVSLTETTEQHAARLGAYIDYFQIQSGI
                     IIFSDLISLEELRLSLIQQLQIPFILVGCTSVNTVSSFGKALLCHNSHFFETLTPQYS
                     FPCYIHQPKQREKILLAVCPTGGVSKKLKNILNQSIPQTVPLRVIDMPYDQIKLEEEK
                     LLLLKQYEPIGVIGVMNPCISGVPFIYLHELTAEYAEPKIYSIFSSVAEPEQIADIVK
                     NLVRNLSLDRLIGNITILDGSRLLINISNCLDYYEQITEHSLSNRIRYCLYFHISCLV
                     ERLIRKEPITTCGNLEYFIQTEQTAIQNIKSSFSELEIAYGIDVPDAEIKYLSDILLE
                     SH"
     gene            complement(28599..29165)
                     /locus_tag="ACZPCR_02045"
     CDS             complement(28599..29165)
                     /locus_tag="ACZPCR_02045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004846116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0032217 - riboflavin transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0032218 - riboflavin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HIR1229704.1"
                     /translation="MSKTAASYPQTGRAQTLRLVKMSSMVAISIVLVYLIHFPIFPAV
                     AFLEYDPADISILIGTFAFGPAAGVLLTLVTSVIQGVTVSAGSGLYGIIMHLLATGTL
                     VVISGSVYHIRKTRTSAVIGLVLGMMGMAAVMLGANLIITPLFMGVSREMVWDLMPFI
                     VGFNLIKAGINGAVTFLLYKRISGFLKK"
     regulatory      complement(29330..29465)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(29501..29827)
                     /locus_tag="ACZPCR_02050"
     CDS             complement(29501..29827)
                     /locus_tag="ACZPCR_02050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3870 domain-containing protein"
                     /protein_id="HIR1229705.1"
                     /translation="MKDETVYVTGESRTSVENAITKTYGAFYVAFEINGRTGEIVEAD
                     CSGTLELTRSFVRRMFVGKRILEDDQKIEEEIRRRYFGSSVKALLVAYRDARKRFGQI
                     QERGQI"
     gene            complement(29973..30740)
                     /locus_tag="ACZPCR_02055"
     CDS             complement(29973..30740)
                     /locus_tag="ACZPCR_02055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA];
                     GO_process: GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HIR1229706.1"
                     /translation="MKQDICAFLQGKQGKVCVSFYDLNAGEGFSIRGTERVPSASTIK
                     LVILAEAMRRMREGELSLEQTITVTEEMRTGGDGILKELLPGHTFTLREILTLMIIVS
                     DNEATNILIRMLGMDSVNRMASELGLKEACLGRLMMDSEAKKQGRDNYICADDMTEIF
                     RQIYAGQCVGEEESRLMMDILRRQQQGGRLQLYLPEEIETAHKCGDLDALENDGGIIF
                     LPGRPYILTVLTSEMESNKEGREVIGHISRIVFDALS"
     gene            complement(30799..32106)
                     /locus_tag="ACZPCR_02060"
     CDS             complement(30799..32106)
                     /locus_tag="ACZPCR_02060"
                     /inference="COORDINATES: protein motif:HMM:NF014500.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015128 - gluconate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0035429 - gluconate transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntT/GntP/DsdX family permease"
                     /protein_id="HIR1229707.1"
                     /translation="MESTMIFGISPIFALLPLIIYIILAFKDINPVLNVVICVVLSAI
                     MTKQPFSSMGEVLGSALGSFLGIIGFIIMLGSALGAVLKETGAAEFLIMTLMKKIGIN
                     SEKKAILASMVTSIVIVALLGSLAGANAIIAPMIIPLVAIIGITPSTMAAVLMGAGIT
                     GLFIGPYSPQVVTIMSLTGMTYSQYIIQTGLPVAALCWVTTFICASRIQKKTKGVYQY
                     ELEETVEKDYVPSAGAKRATAAFAICMAAMIGYGIYLQSGSTYAILVISVTAIVTGLA
                     GGIHPDRLFEVMIEGASKMMWLFIMFVLFTPFITFVSEAGAFDALVKIIEPLLHSNSK
                     VIVALVTALTGIFGVGGAAAAQSVVMDSMFKELVTAIGMSTGLWATILLVGSQITSFA
                     YPEADMMGQMGLARSKDLKNMVKFGITITAVTVIYVGIRAMFG"
     gene            complement(32119..33219)
                     /locus_tag="ACZPCR_02065"
     CDS             complement(32119..33219)
                     /locus_tag="ACZPCR_02065"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009216250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016855 - racemase and epimerase activity,
                     acting on amino acids and derivatives [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide epimerase"
                     /protein_id="HIR1229708.1"
                     /translation="MKITQIRTGLLSVPLRTPFKTALRTVTHVNDVIVEIHTNTGCVG
                     YGEAPSTGVITGDTRGSVRGAIEEHIRPALLGREVDEFEDLMRRLNSCIVGNKSAKAA
                     VDMALWDLYGQLHHIPVYKLLGGSRRQICTDLTISVNDPEQMAEDARQAVKRGYDCLK
                     IKVGVNPALDVERLTAVRQAAGADVSIRIDANQAWTPKQAVSILNQMQEKGLGIEFAE
                     QPVKAADLEGLKYVTDHADIPILADESVFSPQDAVKIMQMRAADLVNIKLMKCGGIYN
                     ALKIAAAAEIYGVECMIGCMLEAKVSVNAAVHLACARQIITKIDLDGPGLCSEDPVEG
                     GAEFREKTITVNDSPGLGIVRVSGIVYDEEDR"
     gene            complement(33813..34715)
                     /locus_tag="ACZPCR_02070"
     CDS             complement(33813..34715)
                     /locus_tag="ACZPCR_02070"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229709.1"
                     /translation="MRKRNITGLLFAAALVMAGSQMGVLESQARPHHGDDWEDRWEDR
                     WDDDRWDDDDDDDDDDHHWGGGNHHHGGNGGNDDGEHRPAVGGFVNVVYFCEEDNTVW
                     ANGEIWAAGLADGKGNVNSSELTNVPEGYKLKEVGDFYYDGGAELRIQVVPNVVKGGM
                     VNVVYECKEENHVWANGEIWAAGLVNGKGNVNSSELTNVPEGYKLKEVGDFYYDGGAE
                     LRIQVVPEETRGGYVNVVYYCEATNHVWANGEIWAAGLVNGKGNVNSSELTNVPEGYK
                     LKEVGDFYYDGGAELRIPVIQWYR"
     gene            35094..35624
                     /locus_tag="ACZPCR_02075"
     CDS             35094..35624
                     /locus_tag="ACZPCR_02075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008397321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HIR1229710.1"
                     /translation="MILCAMFVALIAAGAFIKIPIPVIPFTLQYLFTMMAGLLLGPKK
                     GCLAVLIYILLGLMGLPIFAQGGGIGYLVQPSFGYLAGFAAGAYVTGFLAEAEKYPGI
                     RRLLAADFAGLGIVYSLGMAWYWLISRFYLGTPIGLWPLFLYCFLLAVPGDILLCIAG
                     AYLGKRLIPLVKSGMI"
     gene            35643..36338
                     /gene="bioD"
                     /locus_tag="ACZPCR_02080"
     CDS             35643..36338
                     /gene="bioD"
                     /locus_tag="ACZPCR_02080"
                     /EC_number="6.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008708217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004141 - dethiobiotin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dethiobiotin synthase"
                     /protein_id="HIR1229711.1"
                     /translation="MNKSLFIIGTGTDVGKTYVSGLILKKLRESGASAAYYKAAMSGN
                     ERGGDGVLIPGDALWVKEHSGIAQPLQEMCPFVYEAAVSPHLAARLEGHPVDLDTVMS
                     GFRSLRNCCEYLTLEGSGGVLCPLRFDGQELWLTDVIRSCGSGCLLVADAGLGTINQA
                     GLTAFFLKQQKLPLKGVILNHYQPGNVLHEDNKKMCEYVTGVKVAACVQDGDKDLRIS
                     AGDLKALYEEEIK"
     gene            36335..37534
                     /gene="bioA"
                     /locus_tag="ACZPCR_02085"
     CDS             36335..37534
                     /gene="bioA"
                     /locus_tag="ACZPCR_02085"
                     /EC_number="2.6.1.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006857139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004015 -
                     adenosylmethionine-8-amino-7-oxononanoate transaminase
                     activity [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase"
                     /protein_id="HIR1229712.1"
                     /translation="MIWYPYEQMKTMAPPISITGAKGVYLYTEKGKMIDSVSSWWSVI
                     HGYNHPELNQAMIDQVGRFSHVMLGGLTHEPVQRLAGRLEEFLPGDLNYSFFSDSGSV
                     AVEVALKMALQYYMNRGETERTLTLALEHAYHGDTFKTMETGDDEDYHFVLKAYGPSR
                     HVIHIPTEIPALEQAFEQYHSRLNCLIVEPLLQGAGGMRMYSLSFLKRARQLCDQYGV
                     LLIFDEVATGFGRTGNRFVSDLVLPDILVLGKALTGGYIGHAATVANEKVFRGFFDDQ
                     PEHALMHGPTFMGNALACSAALKSIELFETQDYMAKIRRIEAITRRELDGFSDDRIRE
                     IRIMGGCVCIEVKDASILEGYQKFARERGVFSRPFLNYLYAMVPYVIAEEELVQVIQV
                     MKEWFRR"
     gene            complement(37668..38294)
                     /locus_tag="ACZPCR_02090"
     CDS             complement(37668..38294)
                     /locus_tag="ACZPCR_02090"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229713.1"
                     /translation="MSWLLLALFIGRQLFGFLGSFSEFFAGMPSVLHGIFGGAILWYI
                     LKLTKLDKFVDLKTIKMAGGFCLEITVFTAMATLDLEFISTYIVPVLIYTAILSILTI
                     PIIFGLARRFCRDEWFEKACMAFGAATGNTSTGLALVRAVDPESQCSAGDTHGVYSAL
                     MSWKDVFVGLAPMWLMSGIGLTFGVGVAIMVGFAAAGFIFFGRKRANA"
     gene            complement(38295..38987)
                     /locus_tag="ACZPCR_02095"
     CDS             complement(38295..38987)
                     /locus_tag="ACZPCR_02095"
                     /inference="COORDINATES: protein motif:HMM:NF015573.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015501 - glutamate:sodium symporter
                     activity [Evidence IEA];
                     GO_process: GO:0015813 - L-glutamate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HIR1229714.1"
                     /translation="MTVASFCDDMLILAVFMLVGFFVREIAKPLQKLFLSSSLIGGLV
                     LLILGPQIAGVVNVPESFSSMPSVMIDIVMATTVFGVTINRKKMGSYLDYSCMTMTSY
                     GMQMALGVLLGFVLQKIWPGLPDGWGIMGVFAFHGGHGTAAAAAATFDKLGVPGNMSV
                     GMVLSTLGLVVAMVVGMIMVNYGIRKGWGTYVKEPQKQPDYFYGGVLPKEKRAASGHT
                     VTTSISINHLAL"
     gene            complement(39123..40094)
                     /locus_tag="ACZPCR_02100"
     CDS             complement(39123..40094)
                     /locus_tag="ACZPCR_02100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HIR1229715.1"
                     /translation="MNLQSLYYFVELAKELHVTHTAQKLYISQQNLSQHIQKLEQYYG
                     VTLFNRKPKMTLTYAGEQLLAVATKILAEENELINRLSNISTNRKGHLKVGIPGYRGQ
                     ICLPEILPPFYEKWPNVSIDLVSESSGIMEKKLFDGELDLFIGIMYQDKPKLKIESIL
                     NDQIYLVCSDRLLQQYFFDSWEKVKRESLSGVDLKEFAKVPFLMPKAPMKLRRIVDQC
                     FQEAGVVPEIKFETQVIELYMSLYAYDYGAFFCTQMRMPTLLAMHPDANAFPLFMNGE
                     PVQHRLVAAYHEERFLPDYALDFISLTKQVLEKIAETRPQNQHYPVL"
     gene            40362..41063
                     /locus_tag="ACZPCR_02105"
     CDS             40362..41063
                     /locus_tag="ACZPCR_02105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007038222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RraA family protein"
                     /protein_id="HIR1229716.1"
                     /translation="MAVGKRIYLKRHMPDPEVMMQFKTIPASNTGDVMGRNAAMNPRI
                     KLVNSPKDQMMVGPALTVKARGGDNLALHAALNIAQEGDVLVVSNEGDNTRALMGEIM
                     MAYLRHTKKVAGIVLDGPIRDIDEIGKWDFPVYATGTTPGGPYKEGPGEVNVPIACGE
                     VSVNPGDIILADPDGVIVIPRKDAPQILEDAKKFQAADESKLVAATNGTANRAWVDKA
                     LEAKEFEIIDGIYEP"
     gene            complement(41160..41819)
                     /locus_tag="ACZPCR_02110"
     CDS             complement(41160..41819)
                     /locus_tag="ACZPCR_02110"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004606521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HIR1229717.1"
                     /translation="MAQAQVNPTRMELTRLKKKLATAVRGHKLLKDKRDELMRQFLDL
                     VKKNMALRQEVEAGIKSANVNFVIAKAGMSGQALNAALIAPKQEVYLEAEKKNVMSVD
                     IPVFRYKTRTADENDIYPYGFAFTSSDLDGAVKSLQDVLPQMMKLAETEKSCQLMASE
                     IEKTRRRVNALEHVIIPETQKNIKYITMKLDENERSTQIRLMKVKDMMLEEAHHYTEK
                     A"
     gene            complement(41834..43207)
                     /locus_tag="ACZPCR_02115"
     CDS             complement(41834..43207)
                     /locus_tag="ACZPCR_02115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004606523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HIR1229718.1"
                     /translation="MPKEYRTIQEVAGPLMLVRGVENVTYDELGEIELANGETRRCKV
                     LEIDGGNALVQLFENSTGINLSNSKVRFLGRTMELGVSEDMLGRVFDGLGRPIDGGPE
                     ILPEERRDINGLPMNPAARSYPQEFIQTGVSAIDGLNTLVRGQKLPIFSASGLPHANL
                     AAQIARQAKVRGTDEPFAVVFAAMGITFEEAHFFEESFKETGAIDRTVLFINLANDPA
                     VERIATPKMALTAAEYLAFEKNMHVLVILTDITNYADALREISAARKEVPGRRGYPGY
                     MYTDLASIYERAGRQNGKTGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     RKGVMPPIDVLPSLSRLKDKGIGEGKTRADHSNTMNQLFAAYARGKEAKELMVILGEA
                     ALSDVDLIYAKFADAFEKEYVSQGYETDRSIEETLKIGWKLLSILPRSELKRIDDKFL
                     DLYYGKE"
     gene            complement(43208..44977)
                     /locus_tag="ACZPCR_02120"
     CDS             complement(43208..44977)
                     /locus_tag="ACZPCR_02120"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004221417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HIR1229719.1"
                     /translation="MSKGVIKKVAGPLVIAEGMRDANMYDVVRVSSQRLIGEIIEIHG
                     DQAYIQVYEETSGLGPGEPVESMDMPLSAELGPGLITSIYDGIQRPLDDIMKATGSNN
                     LKRGVEVPSLKRNLKWNFVPTVKAGDTVEAGDIIGTVQETIVVVHKIMVPNGVRGTVK
                     EIRAGEFTVEETVAVIATETGDRELTLMQRWPVRQGRPYKKKLPPEMPLVTGQRVIDA
                     FFPIAKGGVAAVPGPFGSGKTVIQHQLAKWAEADIVVYIGCGERGNEMTDVLNEFPEL
                     KDPKTGHSLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGHVVCNGSEGREGALSAIGAVSP
                     PGGDISEPVSQATLRIVKVFWGLDSSLAYKRHFPAINWLTSYSLYVDNMGKWFNEKVS
                     PEWMTCRQGMMSLLQEEAELEEIVKMVGMDALSPTDRLKMEAARSIREDFLHQNSFHD
                     VDTYTSLRKQFLMMKLVLAFYEKSEKALKDGAGVQGLIKMPVREKIGRFKYVLDENIE
                     TEYEAVTKELEAEIADVLRREDF"
     gene            complement(45037..45357)
                     /locus_tag="ACZPCR_02125"
     CDS             complement(45037..45357)
                     /locus_tag="ACZPCR_02125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004848552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HIR1229720.1"
                     /translation="MYKMAVVGDYDSIYGFAALGLDTFPADGPEKLEQVFHSLVSGGY
                     AVIYMTEAAAAQISRTVERYRESLLPAVILIPGVSGNTGKGIEGVKKSVEQAVGSDIL
                     FGGV"
     gene            complement(45350..46324)
                     /locus_tag="ACZPCR_02130"
     CDS             complement(45350..46324)
                     /locus_tag="ACZPCR_02130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008399067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000220 - vacuolar proton-transporting
                     V-type ATPase, V0 domain [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V0D/AC39 family V-type ATPase subunit"
                     /protein_id="HIR1229721.1"
                     /translation="MADKNYTYAVARIRAMETALFSSSVIEQLMAVKTWSGCLDFLRE
                     KGWGSGNLNEGAEEMLEAEEAKAQKTVRDLLGGDDRILSVFSYQKLYHNLKAAIKKTA
                     SPDFPGELYYDGCGVDGTEMERIVAEKDFKALPEHMQSVAKEAYETFRHTGDGQLCDA
                     MVDRAALEAVYSEGKRSGEPVLMAYAESVTAVADIKIAVRSQKTGKSLEFMRQSMAPC
                     ESLNTERLSMAALSGVSAICEYLEGTSYKEGAEALKESPSAFERWCDNQLIESIKPQK
                     YNPFSAGPLAAYLLARENEIKTVRIILTGKLNNLPEEAIRERIREMYV"
     gene            complement(46336..46953)
                     /locus_tag="ACZPCR_02135"
     CDS             complement(46336..46953)
                     /locus_tag="ACZPCR_02135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015544803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HIR1229722.1"
                     /translation="MEGETDMTGLEKITDRILAEARAQAGEIREKAEEEAGAVLRETE
                     KRLSRLREEAKEREALVKKELETRARSSASLKKRQLILAAKQDMIREQIEKAHQTLLA
                     MEPEEYFSLIEQMVRRFALPKEGEICFSQRDLKRLPEQFGKRLEQAAAERGGSLKIGV
                     EPASLDGGFLLDYDGIEENCSFQALLAAKRDECSDQIQKLLFEKE"
     gene            complement(47012..47485)
                     /locus_tag="ACZPCR_02140"
     CDS             complement(47012..47485)
                     /locus_tag="ACZPCR_02140"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018593354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HIR1229723.1"
                     /translation="MSEMGIVFALLGAAVAVGLAGIGSAIGVGMAGQAAAGVVTEDPG
                     KFAKVLILQLLPGTQGIYGLLVGFLVLSGTGLLGGGADMNMSLATGLLYFLACLPIGI
                     VGLVSAIHQGRTAVASIGIVAKKPEQFGKAMLFPAMVETYAILALLVSILAVSAL"
     gene            complement(47489..49501)
                     /locus_tag="ACZPCR_02145"
     CDS             complement(47489..49501)
                     /locus_tag="ACZPCR_02145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0033179 - proton-transporting V-type
                     ATPase, V0 domain [Evidence IEA];
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HIR1229724.1"
                     /translation="MAVLQMKKITICALLTDRKQVLDFLQGAGVVEISRLEEPEGSDF
                     QRPDTSARRQSCERDAWTAEQALEVLDQYAPEKTSLLSGLAGKPLASGEEFAAVQENC
                     QLIMDDVKQILEYSRKIGESRAAIAKLEAQIESLSPWLALDVSMQCSGTERTVLFIGA
                     AGAQTTLDSLYQAVAERAPSADVSIQLIGKDKDQVCAAVLCLKEDGAQVEEALRAAGF
                     AKPSQSFDQVPAVKKQELEEEIRQIRDEIRAVEEKLRAYGTSRENIRLLSDYCRMRAE
                     KYQALGNMLQSGKTLLLTGFVPEQEEEKLLSRLNERFALYVQTEEVPEAEEAPVLLKN
                     STFAESAEGVTASFGLPARGEMDPTSVMSLCYVFFFGLMLSDAAYGLIVFLACFILLK
                     KFPRMGSGLKKSIRLFMYCGVSTLFWGVMFGGYFGDAVNVISRTFFGREISIPAVWFT
                     PLDDPMKMLVMSMLFGVIHLFLGLGLKGYMLLKDKRILDFFCDVVLWYCLLTGLILIL
                     LPSELFASMSQMTIVFPEPVNLLAKVLAIGGAAGILLMSGRSSKNPALRLALGAYDLY
                     NITSWLSDVLSYSRLLALGLATGVIASVINQMGSMAGNGILGAVVFILVFLVGHGFNL
                     AINLLGAYVHTCRLQYVEFFGKFYEGGGRMFEPFRRNTKYADIKED"
     gene            complement(49540..49854)
                     /locus_tag="ACZPCR_02150"
     CDS             complement(49540..49854)
                     /locus_tag="ACZPCR_02150"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229725.1"
                     /translation="MVKETILAVQEAEAQASGLVSEARQKGKELAEQTRREAQSRSEA
                     AEREIRESLEAVRNAAKLEEEEILSEAGREAEAEISLMRKRAEEKSEEAVRLITDILL
                     KT"
     gene            50319..52277
                     /locus_tag="ACZPCR_02155"
     CDS             50319..52277
                     /locus_tag="ACZPCR_02155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013272470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 interaction domain-containing protein"
                     /protein_id="HIR1229726.1"
                     /translation="MKRIVIITDRKRIAEKIREDLLCVFRGKAELETLTFEEIAKMET
                     VDGDLLLFTLGDRIERIKEKLLHLENIVVIRRTIREKNLVKLFEIPQGTPVLVVNDNY
                     ENTLQTVNLLYDLNVDNLILKPWNGTDGGDDITIAVTPGEAERVPSFIKRIIDIGDRC
                     VDLATFMDIIYRLQLGGEEISKRLLSYSDGIVNSNRGLNQYYKETIMKNIQMKHVLES
                     VDLGILLTIPDGTIVLCNKRFREMIKKPVREGVTQLSSLFDESLFDFFSRDSFDFEPA
                     RFGVCEMTVRKSRLNYDSSVYQDLYFFRDITYVKSLEEKISRQAKTQGFTARYQIQDI
                     LYQSDSMRRCLESVRIFSPGNKTILLEGESGTGKELIAQSIHRLSDRSLQPFVAVNCA
                     AVPENLLESELFGYVRGAFTGASRDGKPGLFEQADKGTLFLDEIGDMPVGLQSRLLRV
                     IQEKQIMRIGSDRVINIDVRIIAATNRDLRQEMKRGQFRSDLYYRLSVLPVSVPPLRE
                     RKEDILLLFSSFLSAPCDVPERVRRILLAHDWPGNVRELRNAAEYFELMKNRENCLPD
                     YLMRLESSLLSEEEKQLLILIRNAQDAGSPTGRSFLRQSLSELLGAPVSEYRLRRLLD
                     ELEEKGLAVKHTGRNGTRITEQGRRLLR"
     gene            52691..53419
                     /locus_tag="ACZPCR_02160"
     CDS             52691..53419
                     /locus_tag="ACZPCR_02160"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF019342.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016811 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in linear amides
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HIR1229727.1"
                     /translation="MENPIIGVFADTMSCNKGGFGDVTRQYINAAYISAVEDAGAVPF
                     IIPVSNDLEKTKKLIDLCDGLLFPGGEDIDPGYYGENPHKNLGEIRPEVDKFLFHSLL
                     YALEQRKPALGICKGMQMMVVATGGSLYQDIYSQREEETFLHCQSGRRTYGVHQVQID
                     KDSRLFQILETGQIATNSMHHQSVRTLGKGLRLSAHTEDGIVEAVESLDGRLIGVQWH
                     PEEMVPESGAMKRLFKNLVQRASV"
     gene            53485..54834
                     /locus_tag="ACZPCR_02165"
     CDS             53485..54834
                     /locus_tag="ACZPCR_02165"
                     /inference="COORDINATES: protein motif:HMM:NF015563.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HIR1229728.1"
                     /translation="MSMWKIILIVNLAVYILSFIIPSGAYQRDGKMAVPGTYAVVDKT
                     YLNPIDVILAVGDTVYSSFGQLFVTLIIMGGMMGIVNSTGVLDRALGNLIHRLKDKAL
                     AIIPIYVFATALLGCVGSMISTVILFVPLGLLIAKQLRADRTFAVGLVILGSFTGFMS
                     SPINPLTGVMGQEIAGLVPYSGAGLRTIVTILNVSVVSAYLIWWAKRCQKNKAVYERD
                     FGGEKALEPEDYERTYQPLSGREAAILVVFFGAFIFFAAGGPTLGLGMTQLGSIMLSV
                     AFVEGILAGYKLDDIMSNFVKGTQSMCGVMVFMVLASIMSIILNQAGILDSIVYYISI
                     PLSHLSSAMAAVGMFIANAFINVFIGSGSGQTVVAMPIMAPLADVVGVTRQMAVLTLQ
                     YGDGFTNLFLPTNVNLMACLAMAGVDFKRWIKFLVPCYAILFVIMVISIFIGTAIGF"
     gene            54852..56069
                     /locus_tag="ACZPCR_02170"
     CDS             54852..56069
                     /locus_tag="ACZPCR_02170"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20 metallopeptidase family protein"
                     /protein_id="HIR1229729.1"
                     /translation="MISDKTLQEELIQLSDELEKQTIQLRREIHQCPELSFHEYKTSR
                     VVMRELERIGIPYEESPQKPGIIATIDSGKPGKFLMLRADMDALPIQESTGLDFESQT
                     SGVMHACGHDVHTANLITVGEILFRTRERWNGKIKLVFQPAEENGGGGREMIKAGLMQ
                     EKPDACFALHVKNGVPGRIFLKQKYLSSYSDSYTLTIRGRAAHSSTPEEGVDAIYIAS
                     ALIMALHGISSRNLSPMAQSTLNVGTIQGGSAPNIIADQAVLGVMLRNVSKESRQAMR
                     LQIETLAKGISESMGGTCEIAFRAGYPAVYNDIDFTKFVEQTFRGNAECLYSNIKDGR
                     PENWLITDLDPMLGAEDFGFFAQEAPSCMIFVGTGGDAPMHNPNFQVDEQYIKLCTRA
                     MALTAAEYLSSAR"
     gene            complement(56142..56852)
                     /locus_tag="ACZPCR_02175"
     CDS             complement(56142..56852)
                     /locus_tag="ACZPCR_02175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008399061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1229730.1"
                     /translation="MAEVHYLISDASKKVDVEAHVLRYWEEELELGIPRNEMGHRYYT
                     EFHIRLFRQVKMLKDKGYQLKAIKTALAKSLESDGKVIIPNEVLEEDVLAALKDADPA
                     GGGSGEASEAQTVPGTAVSCAEETKQGGSVEELVESGQLEQVQRLLNHVIGRAMEENC
                     EKLSQDIAYMVHEKLLKEMDYLMRVADEKEDERFRQLDEMIRACQKDNQCRMEAAATK
                     IPFLRFKKRKFGRNGNKL"
     gene            complement(57079..58410)
                     /gene="dnaB"
                     /locus_tag="ACZPCR_02180"
     CDS             complement(57079..58410)
                     /gene="dnaB"
                     /locus_tag="ACZPCR_02180"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HIR1229731.1"
                     /translation="MDEALIKRVLPHSVEAEQSVIGAMLMDREAIISASEIVTGADFY
                     QHQYGVMFEAMVELFNEGKPVDLVTLQNRLKEKDVPPEVSSLEFVRDIMTTVPTSANV
                     KSYAGIVREKAVLRRLIKINEEIANTCYAGKDKLDDILAHTEKSVFDLLQSKGSGDFV
                     PIRQVALNVLDKIETASKNQGNVTGIPSGFHDLDFRTSGFQPSDFVLIAARPSMGKTA
                     FVLNVVDHIAVRKNMPCMVFSLEMSKEQLVNRMLSMESRVDSQKLRTGTLSDSDWDAV
                     VEGIGTIGNSKLIIDDTPGISIMELRSKCRKVKLEYGLSIVIIDYLQLMSGSGKGGEN
                     RQQEISEISRSLKALARELNAPVIALSQLSRACETRPDHRPMLSDLRESGAIEQDADM
                     VMFLYRDDYYHKDTENPNIAEVIIAKQRNGPIGTVNLLWRPELTKFENLAK"
     gene            complement(58413..58859)
                     /gene="rplI"
                     /locus_tag="ACZPCR_02185"
     CDS             complement(58413..58859)
                     /gene="rplI"
                     /locus_tag="ACZPCR_02185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002577176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HIR1229732.1"
                     /translation="MEVVLLEDVKSLGKKGQIVKVNDGYARNFILKKNLGVEATAQNL
                     NDLKLQKANEQKIAAEHLAAAKDLAKFLEDKSIALSIRAGEGGRAFGSVSGKEIAKAV
                     SEQLKIDIDKKKLVLPEPLKTFGTHEVPVKLHKDVTGTLRVKVTEA"
     gene            complement(58861..60903)
                     /locus_tag="ACZPCR_02190"
     CDS             complement(58861..60903)
                     /locus_tag="ACZPCR_02190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HIR1229733.1"
                     /translation="MKEDIRIQGQLRAYLQWPLFMAVILMAANVVVGLMDLKAGIVMT
                     GFTLFYAAVCGWLYLYKRKRLLGGLLEFSAQYAELQEHIAADMAFPYAIADESGLLLW
                     MNDGFADIVRDDRKNKTLFGLFPELTREILNGIDGEGSLHITYGDSFYRMELRHICAG
                     ENGELNLDAPDGDEDETLWAVYLFDETELLALKQEIADQNLVAGLIYLDNYDEALESV
                     EEVRRSLLVALIDRKINKYISNLDGIVKKLEKDKYFFAIKQKYTKELEKERFALLEEV
                     KTVNIGNEMAVTLSIGMGMNGETYIRNYEYARTAIDMALGRGGDQAVVKDGAKITYYG
                     GKSQQLEKTTRVKARVKAHAMRELMETKDKLLIMGHRIGDPDSFGATIGIYRIAAAFN
                     KKAHIVINSVNSSVRPMMERFQNNPDYPEDLFLTGDEAAARADANTMLVVVDVNRPSI
                     TEAPELLKMVKTIMVLDHHRQSSEIIENAVLSYVEPYASSTCEMVSEILQYVGDGIKM
                     RSVEADAMYAGIVIDTNNFMNQAGVRTFEAAAFLRRNGADVVRVRKLFRDRVEDYRAR
                     AEAVRRAEIFEKEFAISECPSEGLESPTVIGAQAANELLNIIGIKASFVMTQVKDTIF
                     FSARSIDEVNVQVMMEKLGGGGHRTIAGAQLKDATMEEAREKLKAMLRQMIEKGEI"
     regulatory      61070..61177
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            61276..62622
                     /gene="thiC"
                     /locus_tag="ACZPCR_02195"
     CDS             61276..62622
                     /gene="thiC"
                     /locus_tag="ACZPCR_02195"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HIR1229734.1"
                     /translation="MNQTAHPAPGPSSRTYSTQMDAARKGILTKEMEAVARQERFDTK
                     RLMGLVAEGKIAIPANRLHTCLHPNGIGSMLRTKINVNLGTSRDCVDLDMELQKVSDA
                     VAMGAESIMDLSSFGDTRKFRRKLTAECPAIIGTVPIYDAVVYYHKPLGQITADEWID
                     IVRMHAMDGVDFLTIHVGINKNTASRFKQAKRLTNIVSRGGSIIFAWMEMTGEENPFY
                     ARFDEILDICREYDVTLSLGDACRPGCLEDASDISQIEELVTLAELTRRAWEKDVQVI
                     IEGPGHMPLDQIAANMKIQQTLCKGAPFYVLGPLVTDVAPGYDHITAAIGGAVAAAAG
                     ASFLCYVTPAEHLRLPDRDDVKEGIIASRIAAHAADIAKGIPGASDWDRSMSEARKKL
                     DWEEMFRLSIDPEKARRYRASSKPEKEDTCSMCGNFCAVKNMNRILDGEIVSIFDE"
     gene            complement(62782..63396)
                     /locus_tag="ACZPCR_02200"
     CDS             complement(62782..63396)
                     /locus_tag="ACZPCR_02200"
                     /EC_number="2.7.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0050145 - nucleoside monophosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidylate kinase-like family protein"
                     /protein_id="HIR1229735.1"
                     /translation="MSKKIITISREYGSGGRQIGQLVSKKLGMDFYDKELIDLAAKEI
                     GFSPELIADKEQRVTNSLLYNFAMGSLYGIAYPRTPKPEELPLTEQIFIAQKKIIQDA
                     ARRSSCVFVGRCADYILKDRDDVLKVFIYCDKEIRRQRALAEYGEIEDYIDEFMHQTD
                     KKRRIHYETFTNQKWGRRENYDIMLNSGQLGIETCVQILCDAVK"
     gene            complement(63538..64899)
                     /locus_tag="ACZPCR_02205"
     CDS             complement(63538..64899)
                     /locus_tag="ACZPCR_02205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1229736.1"
                     /translation="MKKSYEMDMCSGHILKKILIFSIPLMLSGVLQLLFNAADVIVVG
                     RFAGSPSLAAVGSTTSLINLLINIFIGLSVGANVVVARAYGGKRDRDVSESVHTAIAL
                     SLVSGVLLIVMGLAFSRILLEMMGTPDDVLDKAALYMRIYFAGMPVVMLYNFGSAILR
                     AVGDTRRPLYYLSAAGVVNVALNLFFVICLHMDVAGVALATVISQAISAFLVLRALGK
                     SEGGLKLELKKLKIHKNKMFQIFKIGLPAGMQGAIFSISNVLIQSSVNSFGSVAMAGN
                     AASANIEGFVYNAMNAVYQTNLSFTSQNMGGKKYTRITKIMFTCLGTVTAVGMLLGFG
                     AYAFGEDLLRIYSTDPEVIRFGMLRMSIIATTYFTCGWMDTMVGSLRGIGYSVLPMIV
                     SLTGACGLRILWIFTIFSQQRTLTSLYVSYPVSWIITASAHLICYFIITRKMPKKDGI
                     PDA"
     gene            complement(64986..65804)
                     /locus_tag="ACZPCR_02210"
     CDS             complement(64986..65804)
                     /locus_tag="ACZPCR_02210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HIR1229737.1"
                     /translation="MKVIGIGDNVCDKYIHLKTMFPGGQALNFSVYAKQLGADASYMG
                     VFGTDQEAAHVIRTLDELGIEHGRCRQYEGENGCARVTLEDGDRIFLGSNKGGIAKER
                     PLQLDEEDLKYISGFSHVHTSNNSHFDSQLALVKSTGVSLSYDFSGQWKEEEKVAAAA
                     PYADYVFLSCGSVSEEEARDVCRRMKKAGCRKIIATRGSHGAVYYDGEQFLVQPPKLV
                     KAVDTLGAGDSFAAAFLLSVLKGETADRALPAGAEFAAKTCLVQGAFGFGKQFE"
     gene            complement(65985..66713)
                     /locus_tag="ACZPCR_02215"
     CDS             complement(65985..66713)
                     /locus_tag="ACZPCR_02215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HIR1229738.1"
                     /translation="MLNQDAMTPLYVQLMEEVEKSIRSGEYKPGDRLMTEAEMAKKYG
                     VSLITVRKAIGSLTEKGLVVRKQGKGTFVVRPKLFRNMKKLQSFTEMCTQMGVKPGAR
                     MLENRLIPADRKTAESLGVEAGSSVIYISRLRYADQEPVQIEKSYFPLKYAFLLEAKF
                     DDNSLFDYLREKTGLKVTGSEKIIELCRATPEEAALLAVKKGDYLLFVRSTAYDRDGE
                     PVYAGVQVINGDRFALRVYESDGE"
     gene            complement(66867..67133)
                     /gene="rpsR"
                     /locus_tag="ACZPCR_02220"
     CDS             complement(66867..67133)
                     /gene="rpsR"
                     /locus_tag="ACZPCR_02220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007706127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HIR1229739.1"
                     /translation="MAFNKGDKADASKVRRGGMRRRKKVCVFCGEKNGTIDYKDTNKL
                     KRYVSERGKILPRRITGNCAKHQRALTVAIKRARHIALMPYTCE"
     gene            complement(67208..67666)
                     /locus_tag="ACZPCR_02225"
     CDS             complement(67208..67666)
                     /locus_tag="ACZPCR_02225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HIR1229740.1"
                     /translation="MNKVILMGRLTRDPEVRYSQGERAMAIARYTLAVDRRGRRSQDD
                     GAQTADFIQCVAFDRAGEFAEKYFHQGTKVLVTGRIQTGSYTNRDGQKVYTTDVIVED
                     QEFAESKNASQGAGHDGGYQAAQRPAPASAIGDGFMNIPDGVEDEGLPFN"
     gene            complement(67686..67973)
                     /gene="rpsF"
                     /locus_tag="ACZPCR_02230"
     CDS             complement(67686..67973)
                     /gene="rpsF"
                     /locus_tag="ACZPCR_02230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HIR1229741.1"
                     /translation="MNKYELAVVLSVKLEDEERAAAIEKVKGYITRFGGTVTNVDEWG
                     KKRLAYEIQKMKEGFYYFIQFESDSTCPNEVEAHVRIMEPVIRYLCVRQDA"
     gene            complement(68120..68317)
                     /locus_tag="ACZPCR_02235"
     CDS             complement(68120..68317)
                     /locus_tag="ACZPCR_02235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013270970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HIR1229742.1"
                     /translation="MTYEVGDIVKLKKPHPCGSREWEILRVGADFRLKCTGCGHQVMM
                     ARPLVEKSTRGLRSADGEKKA"
     gene            complement(68367..69113)
                     /locus_tag="ACZPCR_02240"
     CDS             complement(68367..69113)
                     /locus_tag="ACZPCR_02240"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008398576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HIR1229743.1"
                     /translation="MGENCAEEKKKRELLKKWIQESRNVVFFGGAGVSTESGIPDFRS
                     VDGLYNQEYDYPPETILSHTFYLRKTEEFYRFYRNKMLFPEVKPNRAHLALARLEQEG
                     KVRAVITQNIDGLHQAAGSREVLELHGSVHRNYCERCGRFYSMEHILSCEGVPKCSCG
                     GVIKPDVVLYEEGLDDSVLSRSIEHIRNADVLIIGGTSLTVYPAAGLIDYYRGTKLVL
                     INKSATSRDSQADLVICGSVGEALAEAAGL"
     gene            complement(69136..70419)
                     /locus_tag="ACZPCR_02245"
     CDS             complement(69136..70419)
                     /locus_tag="ACZPCR_02245"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF024917.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1229744.1"
                     /translation="MQQISFGQGTGQENGFDWAEKIGALADTEEELTAAQLGGISADG
                     SAKAVWQDGLRYADEEEKQRCRELWHEAFPDDSVAFADYYYGEKVKDNRILVKAEGGK
                     LVSMAQLNPYSFVCRGREWPVDYIVGVATAEDSRHRGHMRSILKKMLEDMNRAHVPFT
                     FLMPADEAIYRPFQFAFIYRQPRFQLTEKALETLSCRPCSSREDAVLAASFMEQWLKE
                     RFEAWCRRDEAYAARLMRELASEDGILEFLMKEENGEEKLAGLHGEWGLEKREQRLLY
                     AEDRLVTREKEKEKPAIMARVTDVEAFFQMVSGGDSAAAGAEQSDGTTKKTESEPDGY
                     LEIADPFLPACAGRYAIVTDKAGGARAVKTDEAGEKQSKETLAISIDGLAQWLFGFRP
                     LSEIVAGERRLDGTALPAWTKDVRPIDGVFLDEVV"
     gene            complement(70411..71274)
                     /locus_tag="ACZPCR_02250"
                     /pseudo
     CDS             complement(70411..71274)
                     /locus_tag="ACZPCR_02250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585692.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2156 domain-containing protein"
BASE COUNT        16925 a        19844 c        15658 g        18912 t
ORIGIN      
        1 ccttaaccga tgctgcaaaa ataataaaaa aagaagccgg tgttaaaatc actgtagatt
       61 acacttatgg ccctacaaat gatggtgttt taggatggac tccagggtac atgacttatg
      121 aattatatta acacgttaaa atggtatcta tgtcttttgc tttttaatgt ttacagcgga
      181 atgcggttat tggatacgct gggggttctg tctgtccagc cggatatcag agtattgtct
      241 ggagtaattc tgttatcggc tgttttaatt ctgatgttca ctgacaagct tttacacaac
      301 catgttgatt tcagagcaat gcccttgaaa gttttatttg gaacgggagt tttccttatg
      361 attgctgagt ttatcatcca tgctttatct tgatctgaaa aggagaaaga tccttttcct
      421 gatttcttct atactgaatg aaaacgggaa atgtctcttt ctcctttatt gtttgaattt
      481 ttttaattta cctgaatttt aaatttattt ccggttcgcc ttctccatat ggatattctt
      541 acccttgatc cttacgtcct tcatggcctg gagcaccacg tctgcctgct ctctgggaac
      601 ctctacaaag gtgtacttgt cgtacatgtc gatgcttccc accatttttc ccggcattcc
      661 ggactcgcct gcaatggcgc ccaggatgtc gcccggcttc acgttctggt tctttccaat
      721 attgatgaaa agtctggcca tatcgtctcc tccggatcgg cctcctctgc cgccggagcg
      781 tccgcctctt cctctgccgg aatttctgtc cctgtaatct cccagatcat ctaaggagcg
      841 cagaggcctg gaatcctcga taatgtcctc attgtcctcg cccataatca tgcgcagaag
      901 tcctgccgcc aggtcaaggg tggtgtagtc ctcctccaga accttcttct caataatatc
      961 aatcaggcgg ttcatatcgc tgtcctgcag aagctcctct gcctggcaga gaatcttatc
     1021 tgccttgatc tccgttacgt cgtcaatgga cggaatcggc tgcggcacaa tctttgtctt
     1081 gcagtagcgc tgaatatcgc ggagcttata aacctctttt cccacaacga ggctgaaggc
     1141 ctttccctct cttcctgcgc ggccggtacg gccgattcgg tgtacataat actcctcatc
     1201 ctggggaata tcgtagttaa atacggcttc cacatcatcc acatcgattc ctctggcagc
     1261 cacgtccgtc gccactaaga tatccgttct gccctttctg aagccgttca taacccggtc
     1321 tctctgcacc tgcttcaaat ctccgtgaag tccctccgca aaatagccgc ggccctgaag
     1381 cgccagcacc agctcgtcta cctggcgttt tgtgttgcag aatactacgg acagctttgg
     1441 agcgtacatg tcgagcagac ggcacatcac ctcaatcttg ttcttcggct ttacctcata
     1501 gtaatactga gtcaccttgg gaactgtcag gtctttcttc actaccttga caatctccgg
     1561 ctccttctgg aatttcttcg cgatctccgc aatggctgcc ggcatggtag cggagaacat
     1621 cacagtctgg cgctcctccg gaagctcgct taaaatcgtc tccatgtcct ccagaaagcc
     1681 catgtttaac atctcgtccg cctcgtccag aaccactgtg tgaacctggc cgaacttaat
     1741 ggtctttctt ctcatgtgat ccatcacgcg gcccggagtt ccgataatca cctggacgcc
     1801 gtcctttaag gaacggatct gcttcacaat ctcctgtccg ccgtagatcg gcagtacctt
     1861 gatgccgtgc atgtacttgg ccagactgcg gatttcgtcc gctacctgga tggccagctc
     1921 tctcgtcggg cagagcacaa ctgcctgaag cttcttgttc ttcggatcaa tcttctgaag
     1981 aagcggaatg ccgaaggccg ccgtctttcc cgttcctgtc tgcgcctgtc cgataatgtc
     2041 ctttccctct atctccaggg gaatcgcctt agcctgaatc ggcgacgccg cctcaaatcc
     2101 catatctgtc actgcacgca gaattttcgc gtccaggttt aattcgtcaa atctgattgt
     2161 ctccattcta ttcctttcta aaacttccaa atctttccca ttctccggac atgccttagg
     2221 ccgccttacg gcagatatat gatcttccat aaagcaaaaa aagatccaag accgtttcag
     2281 ttcttgaacc ttcccactgt atgcccagct tactatagca gaattttctc ctcctgtcaa
     2341 tgcgccgcca aaatctgcac agcaaaaact gcaggttttg cgaaagcctt gctgctgctg
     2401 cccagcctgc agtttcttct aatcaggaat tacttcctct ctccagccgc cgcgtccaga
     2461 ccctttcccg ccagcgcgcc tatgagccca ggaagaagcc agcccagccc cagcccatat
     2521 ccgggaagca gcgcaaacag ctgggaaaga acaggaacgc tgattccggc tccctccaag
     2581 gcatagacaa tgctgaccgc tcctgtaagg agcactgtca gacggtacat ggccctgcct
     2641 ccctttcctg caaaggacag gaaaatcaga gcgatggcca ccggataaat gccgtttaaa
     2701 actggcacgg aaaaggccag gatctttgtc agtcctgcat tggacaccgc catgctgaca
     2761 gccgcaaaca gaaccaccca tttcctgtag ctgatccgcg gaatcagctg gcagaaaaat
     2821 tcgctgcagc agcttaaaag gccgacgcag gtattaaagc aggcaataaa gaaaatcagg
     2881 cccagcacca ccgttccggc tgaaccgaaa atccgctccg ccacaaaggt cagaaccctg
     2941 gctccattgt ccagggtctg ggcctccggg ccggccttga ttcccacata agtcagggcg
     3001 cagtacacag acgccagaag cgcgcctgct atcaatccgc tccgtactgt ggacgttacc
     3061 accgcatcct tgtcctctac tcccaccgcc ctgatattga tcgcaataat gattccaaaa
     3121 ttcagagcgg ctatggtatc catcgtctga tatccctcca ggaagccctt caccggagcc
     3181 aggccgctgt aggcttccgc cggcatggga agcgccttcg gttcggcggc tatgctgccc
     3241 gcaaacataa taaaaatcag gcctaaaagc gccggacaca aaattttccc cagacgctgc
     3301 gtcagctttt ccggatgaaa tgccgtcact gccgccagca ggaaaaatac agccgagtag
     3361 atcagctgcc agaaagctgt ctgcgctcca tcgttcaaaa acggaagcac tgtcatctca
     3421 aaagaggtgc tggctgtcct ggggatggcc aggcatggtc cgatagacag atagatcagg
     3481 atggtaaaaa ccatagaaaa cgcaggatgt acctttcccg ccaggcagtc aagccctcct
     3541 gcccgcgaaa cggctatcac tcccagcacc ggaagaccaa ccgcgctcat cagaaagccc
     3601 gccatggccg gccaggcagc cgtcccggcc tgagccgcta aaaacggcgg aaaaatcaga
     3661 tttcccgctc caaaaaacat agaaaacaga gtcaggccta caatcagaag ccgtcttccc
     3721 tttagtgtct cgttcataca aacctcccct ttgataccca atgaatccag tcctgcattc
     3781 ccagaaccgc atagggaatc aacagcgtaa aataagaaac cgtatactgt cccttggcct
     3841 cccagaacag gtggaacaga aatcctccga tgaaaataac ggcgaaaaat aagccctgga
     3901 atttcaccct tcggaaccgg aatactgcaa acagcagcgc gcctgcgtag accagcgtct
     3961 gaaccgcatt gcacagctgc cagtaaatct cattagccgt gccgccttcc ttaaacagcg
     4021 atcgggtaaa ggagggaaac agccatccaa agcccttcac ctcctgaatc caaagactct
     4081 gaaaggtagg ctccgtccat atggagcgca gctttctgtt gaaaaaatca gccgcataat
     4141 cagggtgctc cataaaatac tggattgtgc ggcccagatc gcgctccacc gccgcggccg
     4201 tcagctcccg atcctcccgg ttatccaggt aaatatgcac gttataatta ttaaaccagc
     4261 ccggggctct gctgccctcc tgaagcccca tctccgccca ggtgagcatg ggagggccgc
     4321 cctccaccga atgacccgcc gccagggaaa gcccccccag cactaggctg tggctgagca
     4381 ggtacgcgga cagcacagcg gcggtgccca gaagcggaaa cagctttttt cggaacaccg
     4441 cttccgctat aaaaaaaaga accatagccg tcagcacaat catatagttg gatttgaaca
     4501 gaatagccgc agagatcagg acagacgaaa gaatcagatc ccgctttctc cgctcctcca
     4561 aaaatcttct ctcgtaccat acagccgcag cggaacaggc aaacccaggc agcgtcccat
     4621 aggcgaaggt gacgtaaaag gaaaatggaa gaaatgccat catcagaagt gccaggccgt
     4681 aaaacccgtt tttcatctcc agaacctctt ctgccatttt tcctgtatac aaaataccgg
     4741 ctgccaggca ggccacgttg agcagctgcc acaaaaaagc tgcctgctct cccgcaagca
     4801 gagacagaaa agccgcaaat aatatctgcc cgttctggtg gggataggtg taggcatacc
     4861 cctcaaactc atcataatgg tagcggaagc ctacctggtt ccacggtaat aaatcgcctg
     4921 cagccagagc ttttccacag tcaatcacca gcctctgatc cgacgccggg cgaaacatgg
     4981 tccccatgat ccagatcacg taaaaccctg acagaatgag aagaagccgg acaaagcgct
     5041 ttctgcgctc ctcctgctcc tcccggcttt tttcttctct tccttctgca tttctgacct
     5101 tgagaatcat cactcccaga gccgtaacga gcataaacac aagcagatga tacagcggag
     5161 aatccttgta aaaccacacc tgttcagctc ccccgtatac agctgcgctc cccgttatgc
     5221 tgagatacag aagcaggagc agaatgcctg taaaaataag cagaatcaaa atgcaggccg
     5281 ccgattccag gcaggagcgc tcctccccct gttcccttct tctgctgcgt cctctccctg
     5341 cttctccttt cgcaaggccc ggtatgccgt ctttcgctct tccttctgcc ccttcgttgc
     5401 ttcccccttc tcgtatcgtt tcccagatca tagcgttcct cttatgctcc tatttttctg
     5461 cttccgcagg aatcaggcat gaaattacac cttaaaccgg tatcccacac cccagatcgt
     5521 ctcaatgtac tggggcttcg ccgtgttaaa ctcaatcttc tctctgattt tcttaatgtg
     5581 gactgtcacc gtagcgatat cgcccagtga ttccatatcc cagatgcggc tgaacagctc
     5641 ctccttggta aatacgtggt taggattctg ggccagaaaa gccagcagat caaactcctt
     5701 ggtggtaaag ttcttctcct ccccgttcac atacactctt ctggccgtct tatcgatctt
     5761 cagaccccgg atctcgataa tctcattctc cggcattccg cttccgatca gtctctcata
     5821 gcgggccatg tgggccttca ctctggccac catctcgctg gggctgaaag gcttggtgat
     5881 ataatcgtcg gctcccaggc ccagtcctct gatcttgtca atgtcgtcct tcttggcgga
     5941 aaccataata atcggcgtat tcttcacctc tctgaccttc cggcagatct cgaacccatc
     6001 caccccaggc agcatcagat ccagaatcag aaggtcaaac tcctcctcca gcgctctctt
     6061 aagtcctgtc tcaccgttat tttcaatctc caccccaaag ccggaaagct ccagataatc
     6121 cttctccagc tctgcgatag cctcttcgtc ctcaacaatt aaaattctgc tcattcctga
     6181 attacctcct ggtattttct aagcacaaaa tggatctccg tgccgattcc ttccttgctg
     6241 gaagcccaga ttctgccgcc atgatcctcg ataatcttct tcacaatgga aagcccgatg
     6301 ccgcttcctc ccttggaaga attccgcgag gaatccgtcc ggtagaaccg gtcgaaaatg
     6361 tagggcagat ccttggccgc aattcctttt ccgttgtcct cgatgacaac ctggataaaa
     6421 tctccgtcat ctgtaatccg aaggttgata atgcccttct ttttatccag atacttcaga
     6481 gaatttccga taatgttatt gatgacgcgc ttcatctgtt ccgcgtccgc aataaccaga
     6541 acgtcctcgt ccacatagtt aaaatatccc agctcaattc ctctggtctc catatccagg
     6601 cctacttcct ccacacagtc ccagaaatac tcggctacgt tgattttgga aaaggtgtat
     6661 ggaatcctgt tggtatcaat cttcgaataa aaggtcagct cgtcgatgag cctgtccatg
     6721 tcgttggcct tattgtaaat ggttctgata tacttgtcta acttctccgg cgaggaggcc
     6781 actccgtcct gaatcccctc cacatagccc ttgatggctg tgatcggagt cttcagatca
     6841 tgagaaatat tgctgatcag ctccttgctc tccttgtcat actggatctt ctcctccgcc
     6901 gactccttca gcctgaggcg catctcctca aaatcctggc agagcatccc tatctcgtcg
     6961 tcgttctccg cgtccagggt aaaatccaaa tttccgtccc ggatcttctt cgtcgcctcc
     7021 tgaagctcgt gaagcggccg cagaatcgac cggtataccc acatgaccag cataccgccc
     7081 gtcaggcaga taatagcgat tcccacaatc agcatctcgt tcagcatgga tttaatctcc
     7141 ggcacgtatt cccctacatt cgtcacaatg aaggcgctgc cccggcttct gtcgtcatac
     7201 tgaaaatcaa tctgctttaa cagatgctgc tcctccccgt ccacgtaaaa gccgcctgac
     7261 agcacgtcgg aattgtcctc cccataaggg ggaagctggg aggacagctt ctctccctcc
     7321 ggatccccgg agaaaatgat gtccggcccc tttctcacaa gcagaaagga atactcctcc
     7381 cgcagcgcct cgttcacctt ggccagatac tccggatcct ccagccgatc cggctcattc
     7441 atggctatgt cgcgtatctt cttctgtgaa ttgatcgtca ggcggttaaa cacctgcatg
     7501 gaatttcccg agaggagatc tacctgctcg ctgagcccgt aggttttctg aaaggagcgg
     7561 atctgataat tgctcagagc cgtgatcgcg ccgtaaatca gaaaaatcgg aaccacagta
     7621 attgtaataa aagcgatagc cagacgggtc ttgatcttca taactattct cctttgacaa
     7681 aaatatgaga aaacctgcgc cagcctgcat ggttttctca tattttttaa ctgtcgctgc
     7741 atactctcat tttacttaaa gtataccata ttttcagaag cccgtttcta aaagttatct
     7801 aaaatttctt tccttctcct cagccttttc cgccggctgt ctcctgcccc agacggattc
     7861 tgtactcccc tgccgatatg cccacctggc gcttaaatac atggcagaaa tgcgctctat
     7921 cggaaaatcc cacctccacg gcaatatccc ccacgcgcct ggtcggatcc ttcagcagcc
     7981 ggagggcttc gtcgatcctt acctggttca aaagctctga aaagtttttt cccgtatggc
     8041 ggttcaaaag cttgctcaaa tgccaccggc ttacaaaaat ctgctccgct acccctgcca
     8101 gagtcagatg ttttctgtaa tttcccttaa tatagcacag cgcccgcgcc acaatatacg
     8161 cgccggctga ttccttctgg ccggattcgg cttcagacgt caccggctcc cctggggacg
     8221 gatttttaca cacgttctgt tccacacctg atacccccat tttatccgaa ggcagacggc
     8281 agacagcccc ccgctgcctc ctgccggcac tcctctatct gtactgcctt ccacccgttc
     8341 ctataccaaa atcatatacc tttcgccagg gaaacacaag attttttcaa acttttttga
     8401 aaatacatgc cttgatttta tattaaaaac tattattcag aatagtaaga attattcaaa
     8461 cattcgctcc gcaacagcgt gaaaaaaagg ggcatccgcc cgcatatact tggctatgcc
     8521 ggaaaatgcc ccttctgtct ggaaacggaa tctatttatt ttaaatatgc cttcagcgta
     8581 tccacacggt ctaacttctc ccacggaaga tccaggtcgt ttcttccgaa gtggccgtaa
     8641 gcagccgtct gcttgtaaat cggacggcgg aggtccagca tcttgatgat gcctgccgga
     8701 cggaggtcaa agttttctct cacgagctct accagcttct cgtcggaaag ctttcctgtg
     8761 ccgaaggtat ctaccatgat agaagtcgga tgagctactc cgatggcata ggagagctgg
     8821 atctcgcact tgtcagccag gcctgcagcc acgatgttct tagccacata gcgggctgca
     8881 taggctgcgg aacggtctac cttagtgcag tcctttccgg agaaagcgcc gccgccgtga
     8941 cgggcatatc cgccgtaggt gtctacaatg atctttcttc ctgtcagacc gctgtctccg
     9001 tgtggtccgc cgattacgaa gcgtcctgtc gggttaatga agaactttgt gttcgtatcg
     9061 atcatatggg ccgggagaat cggatcaaac acatagcgct tgatatcctt gtgaatctgc
     9121 tcctggggca ccttctcatc gtgctgagtg gagagaacta ccgcatctaa gcggaacggc
     9181 tttccgttct cgtcgtactc taccgttacc tgtgtctttc cgtctgggcg aaggtaggga
     9241 agagttccgt tctttctcac ctcagtcagt cttctggcca gcttgtgagc cagggaaatc
     9301 ggataaggca tatactcctc tgtctcgtta gccgcaaagc cgaacatcat accctgatct
     9361 cctgctccga tagcgtcgat ctcctcgtcg gacatcttgt tctcttttgc ctctaacgcc
     9421 ttgtcaacac ccagggcgat gtcggcagac tgctcgtcga tcgcagtcag cacgccgcag
     9481 gtatcgcagt caaaaccgta tttcgcgcgg tcgtatccaa tctcacggac tgtctcgcgg
     9541 acaattttct gaatgtctac ataagcgttc gttgtgattt ctcccataac caggacaagt
     9601 cctgtagtaa ctgccgtttc acaggcaaca cggctcatag gatccttttc cataagagcg
     9661 tccagaattg cgtcagaaat ctgatcgcac attttgtccg gatggccttc agtaacagac
     9721 tcggatgtaa aaagtaactt ctccacgttg ttcctccttt ttgtaataaa tcaatggctt
     9781 cttctgtatg tgcgcatctt taagactttt ttacgataaa acatggtttt tgtcacaaga
     9841 aagattcctg tggagcattt tttatttcat aggacgcttt ttcctatgaa ataaaaaaag
     9901 tccgcagcaa tacggacttg atttcttttc tatcaattcc tcttattgct cgatttgccg
     9961 cgcgtctgcg gttcctcgct caggctggca ccttccattc ttctggggtt gccgtgactt
    10021 ctcagatcct ttgtatctcc atcactctga ataagggata ttacgcacat tatttacttg
    10081 tatctggtat ctaaacagtt ctgcattctt tgcttgcgat tgatatgata tcctattctc
    10141 cctctcctgt caagagaaat atcagcccac cttcagtctg aacttctgag cttccttctc
    10201 ggaatccacc ttctcaatca cagcgcccag gcctcttaac ttctcctcga agttctcata
    10261 gcctctctgt atgtatccaa tctcgtcaac gactgtatag ccctcggcgg ccaggcctgc
    10321 gattacaagg gctgcgcctg ctctcagatc cggggcgttg actgtagccc ccgtgaagcc
    10381 cttcacgcca tcaataatcg ctacgtttcc ttccacctta atgctgcagc ccatgcgtga
    10441 cagctcgtct acgtatttaa agcggttctc aaaaatgctc tccgtcacca cgctggttcc
    10501 ctcagccaga gccagagtca ccgtaatctg cggctgcatg tctgtcggaa atcccggata
    10561 tgggagcgtc ttaatgtcca tatgcttctg acgcggttta cccaccacgc ggaccgcctc
    10621 gtcaaactcc gtcacctcgc agcccatctc aatcagcttc gcggtaatgg cttccagatg
    10681 cttggggatc acattctgca ccataatatc gcctctggta atggcggcgg cgcacataaa
    10741 ggttcccgcc tcaatctgat ccgggataat agaatactcg gttccgtgga gctttcggac
    10801 tcccttaatg cggataatat cggttcccgc gcccttgaca ttggctccca tgctgttcag
    10861 gaagttggcc acgtctacta catggggctc cttggcagca ttctcaatga tcgtctctcc
    10921 ctctgccaga gtagccgcca tcatcacgtt gatcgtggct cctacgctga ctacatccag
    10981 gtaaatatgg cttcccacca gatcaatggc gtgggccacc acggctcctc tcttaacctc
    11041 tacctcagct cccagagccc gaaagccctt gatatgctga tcgatcggac ggcttccaat
    11101 gttgcagccg cctggaaggg gaacctccgc gctcttatac tttccaagaa gagcgccgat
    11161 aaaatagtag gaagcgcgga ttttgcggat atactcgtcg tccacgctta cttccttaat
    11221 gtgcttggcg ttgatcctgg ccgtatggcg gtcaatgcgg tccactttgg ccccaatctc
    11281 ctcaatggcc tccagcagca cgttgatatc ccgcacgtcc ggcagattct ctatcaaaac
    11341 ttcttcgtct gtcataattg atgcagctaa tattcccagg gcggcattct tagctccgct
    11401 gatggtgact tcaccgacca ggggattgcc gcctttcata atatactgtt ccatcttgca
    11461 cctctatcta tgcttggcga gaagggctct ggcggacgac gcccgccatg ccctctgact
    11521 gtcccaactc ttacattttt atggattttt tgtctctgtt cctgtgggaa cattaacttt
    11581 ttatgaactg attataacat atcagcagaa tttgtaaaga tgaatacttc taatcttcaa
    11641 acaggaacgc cacaaatccg tttcctccgt tggcctcgaa ccaggacgcc gcatcgttca
    11701 ggcccatctt gtctgtgtag gcctgttcgg ttcccggata ccagaggcag gaaatattgt
    11761 aggcgtcgta tccatagata acggcgtaag agccgtctcc cgtgtaggcg gccaccggat
    11821 agccgcggct gatgaagtaa agaatctgat tcagagaaag gcctcctgcg tcgatgatcg
    11881 cgccgccgtc tgaggtctcc tcatcgccct cctcaaatcc cttcaggtac cgttccaaat
    11941 caggaaccag gctctccgga ttccggatgg taatcatatc ggcccggtcc actctggacc
    12001 agaatacgct tccatcctcg tctgtcacaa ttcccattcc atcgtacgcc gccgtcacag
    12061 cgtccggaaa gctttcaaat acgcctctca gcctgccgcc gctgtaagcg taatactgac
    12121 gcctgccgga aggctctggc tgtcccagca cgactgtatt attttcctct gccaccgcct
    12181 tggacggcac gttcaaatca acgccgccgg aaacggactc tgccgtctgc acgaaatata
    12241 cgcgtccctg ctcctcagag gccagataac cgattccttc catggaatcc tcctctacct
    12301 cctcgttgca gacaagggtg tccgccccgg ccgtcatgta gctgtcccca accctcgtca
    12361 ttctctgaag atgaacgcgg ctgccttcaa tttccacatc tgtaatgtaa acgccctctt
    12421 tctcatatct tgtctgaaga ttcatgtcct ttcccacaat ttccagggca tacataggcg
    12481 cctggacggt acggccattg accttgacgc tggagttttc ctctgccaga ccgtaaacca
    12541 gatcgcctcc cacaaatccc agcaggcgga tgctgcttcc ctccggcgct ttgatctggg
    12601 cgctctttcc cgtttccaga tccataatat ggacggaacg gctgtcgtac agatcctctc
    12661 cgtcctgcca tgcaattcgt tcctggcccg ggcttacggc gaagttctct tccgtcatcc
    12721 cctctgccag aacctgggct tggcgggacg ccgtatccac ggaataaacg gtatttccca
    12781 taagaaggta caaggttccg ctgctgctca gacagctcag agtatccatt cccatcaaaa
    12841 gctcctcgct gctctcattg gccggcaggt aaagacgttc tgtcaaagta ttggttccct
    12901 tctcgtagcg ccacagagaa acgcctactc ctccttcgtg gcttccgcgg ctcatatagc
    12961 cgcttacaag gaaatcaacc gttccgtcgt ctcctgcaga cagaagctta atcccgtaat
    13021 cctgcagatt cgccatctca tccgtctcgc tctggcggaa gctgaatacc ctcgtactct
    13081 ggctgtctgc gcggctgtac atccaaagct ctctgttaac cacaaaagcc tggtactctc
    13141 cgtttggaga tcgcagctcc tgcaggccat ggctgtcgga aatcccaagc ataatccgtt
    13201 tcccggaata ctgttcggag cctccgtcaa aaatctggtt catggttctc tcgtaatcca
    13261 tcatgtagat tctctgagaa ctccatttca tggtaaagct ctccgtgata tcgtaatact
    13321 ctctgtcttg ctcctcctgc gtttccccgg aatcctctcc ctgctctccg gcagtggcgg
    13381 ccacatagct caggcagaga gtggccatat tgccctgaag ctccttcagc tccatttcca
    13441 tatcccctgt tttctccagc gaaaggtttc cccaggtcat ctgatcgaag ctgtttttaa
    13501 gagttacgcg gcccagagag ctgttgtcag ccgccggatc tgtctccaga taggtagtca
    13561 ggtcagaagc cttttcatag tggaaggtat tgtctgaaaa tgtttccgcc atctgaatca
    13621 tcggttccaa ataggcgtcg tccgtccaga caatcctggt atagtagtag atctccggct
    13681 gattttctgt ggcaatggca agggtcagaa tatactcctc ctccttgtcg atcaggttct
    13741 gaatcggcag aatcgttacc gcctccgccg ctccctcgtc ctgatgccag tccttgacta
    13801 ccgtccgctc aatcaggctt tcatcctcca tgctgcggat ttcgtactgg attcccgtaa
    13861 tgcggctgtc caggttgtag aaatctaccg tcagcttccg atcctttgga agcactgtaa
    13921 gatttccgcg gtccgcccac tccctccgat cccccagaaa gccgtggagg cggttcatct
    13981 gtcttcctcc catttccata taggcaaccg ggatgtttcc gtcttcaatc ggcgtgtagg
    14041 ccgcgttctc ctgtttttta tccttaaaag ccgttacagc ggccgcagac aaagccgcag
    14101 ccgctatgac agccatcata atcatccata ctttcttact gatttttttc atgctgttgt
    14161 tcctcaaata ctaaaatcat ctggttagcg tctataatta taccatatcc tcgtaaattc
    14221 taacaagaac gaatcgattt aacggcatcc tctgctttgg catcttctgc gctgaatctc
    14281 tgaaaacagg agaagcgccg cgatgtctcc ccaatccgga ttcccgtgcc cgcctggatg
    14341 attcggtggc ggcagcggag ggccccatgg atggttcggc ggtggcggcg gtggccccca
    14401 tggatggttc ggcggtggcg gcggccccca cggccgcctg gctggccctg ggcctttcgg
    14461 ccctcctctg ccatttacat cttccatatg taaggattcc gtatcccctt cctcccccgt
    14521 ttccatagct tcccccggaa cggccgtttc catggcgcgt accctcggcg ccggattgcc
    14581 tgtaataacg gttccgctgt atgagcagac ctctgccgta taaagcgctg tattctcttc
    14641 ttctgataac cgctctgata cccggcgggc aatcccgcgg ctcagctgtt ccatagccac
    14701 gcgatccgga tattcatcgt aaatagggct tccctgataa tccagccggt cgcagaccgc
    14761 ctttacctcc gcctgaattc cccggagttt tccggggcaa agcatggaaa aatactcaaa
    14821 gtccctgatt gtctccgaaa ggcctgtctt cggcggaccg gcagacggcg aatcggtatc
    14881 taaaaaatcc tgcatacaat atggctcctt tttaaggtta taccatatca tatgcaggat
    14941 cctgcctgct gtttcctatc tgccagcctg aaagaggcag tcttcataga cgccctggcg
    15001 gcaaagctcg cggattgcct ggcttaccgc ctccttgtcc tccttatagg taacgccgaa
    15061 ccatttatcc ttcgtctcca gaaccgccac cttcgcctgt ccccggcgga tcatctggtc
    15121 aatgatggtg ggaagcaggt attctgcctt caaatcctgc gccccgggcc cctttaaaaa
    15181 ctccggaaaa ccggcctcaa gggccttcac aaaggacgga gtcaagcccc acatattcat
    15241 ggaaacgtgc tgttctcctg acacggacac aggatttccc tccttgtcaa aggcggacag
    15301 ttcttcgccc tttttctcaa tctgatacgt ctctgtcacg ctctttaaaa ttccatcctg
    15361 gcctacctgg cagacgccgc gggtgacgcc cccgttttcg ctcagcgtat tggccaggat
    15421 aaatcccgcc atgcagatgt cgtagggctc cccttcccgt tctgtgtcca taacgtctac
    15481 cagataatca tgaatcgtcc ggaatgcttc ttttccataa taatcgtctg cattgatcac
    15541 cagaaacgga tgtttgatca aacctttggc gcttaaaacg gcctggccgg ttccccaggg
    15601 cttctttctt ccctctggaa cagaataccc ctccggcagg tcggaaagct cctgaaaggc
    15661 ataggacact ggagcaatct tttcgatccg ttttccgata atctccttaa aatccttttc
    15721 cagatccttt ctgataataa agataatgtc gttgaagccg gcttccaaag cgtcgtggat
    15781 cgagtaatcc ataataatct cgccgcctgg tccaaccggt tccaactgct taatgccgcc
    15841 gccgaaacgg cttccgattc cagccgccat aattaccagt gatgtctgtt tcataatccc
    15901 tctcctatat acttcctgtt ttcttttgtc cgtcaacagt tctttataat atggacagtt
    15961 tagcacattg cgccgttcat ttccaccctt atttcctgcg aaaccggtct gcgggcttgt
    16021 atgccggggc catagctggt atactgaatt caggatctgc ctccttctcc ggaattttcc
    16081 agaagcagga tttttcctca aattacaaag aaaggaaccg gctgtatgac tgcgaaatat
    16141 tttgtaatac agtgtatcgg atttgccgga actctgctgt tctttttttc ctaccagtgc
    16201 aagagcaacc ggaatctgtt tcgaatccag tttttatcct acttcatcta tacgatccat
    16261 ctgattctcc tgggggcgat gacaggcgga atcagctata ttattaatac cttccgctcc
    16321 ttctgcctgg gcgggaaatg gaaatctgcc aaaagctggg gcatgtgcgc cgtcatctgc
    16381 tttcttcaga ttataaccct ggttctcacc tggtccggct ggatctccat cctccctgtc
    16441 gcggccaata ttgcctcgac aattgcagga tattcccata atccccggaa aatccggctg
    16501 gccggcatgt ttatcaactc gcctctctgg attgtctaca acgccatgtc cggctccctg
    16561 gccggtatcc tggacgaggt cgtcacagag ctttctatga ttatctccat tttccggttc
    16621 ggctggaaat ccctggaccg ggtggaggag taagacgtta cgccttactc ctctttcact
    16681 gccgcaatct ccaaacgcgc catttttcca aaccatggaa ttaatttacc ttttacaata
    16741 aaatgctgtt tcagaaattc actatttctt tcccatactt gaaacccctt cctatcgagc
    16801 tttctgcaca gacaatcttc acacggtttg tccctgccct gaagaacctt gtaacatttc
    16861 tggcctttgt aattatagat tcctgtcatc ttccgccctg cagtgttcat ataatacagc
    16921 tctctcgtat ccatatcgct cacatatatg atttcatcca tgctttccac aatattgaca
    16981 atctcatctt tgcacagctc ctggagcatt gctgtgcttt ctttagaatt gagctgcctg
    17041 aacttatcct ctttctttat tcggaattgg tactcctcag actcttcttc aaaataaatt
    17101 ttttcaatct cttctgctct atatggtttt gcaaataaaa atccctgcaa tatgtctgtt
    17161 ctaagctcct gcagcgcagc cagctcctcc tccgtctcca ctccctcgca gcacacctgg
    17221 atctgagcgt tgtgggcaag ctcaatcata ttgctgagca aacggtaatt gtatgcatta
    17281 tactgaattc tgctgacaaa acatctgtct atttttatct cgtcaatatc gatactcttt
    17341 aaatagctta aactggaata tcctgttccg aaatcgtcga tagcaatctt aattccatgc
    17401 cgtttccatt cataaaaaat cttattaaaa tagctgtaat cctggagctg catgctttct
    17461 gtcacttcca aggtcagcgc gctccccgga agccctgtgt ccctgagaat ttcgatcgct
    17521 tttaaggcaa tatcatcctg tctcagctgc acataggaaa tatttacatt aatgtgaaaa
    17581 tccggcttct tttttctcca tttcacacac tgtctggccg cctcgcgaaa agcccactcc
    17641 cctacctggc agatcaacct gctttgctcc agaagaggaa taaattcagc tggacttaca
    17701 attcccctgg atggcgattc aaaacgcaaa agagcttccg caccataaat ttcaaacctg
    17761 cttccgctaa tctgaggctg atagcaaaga taaaatccct gataattttt cataactgcc
    17821 tcacgaagct catcctgaag ttctatttta tccagacgct tctggtatgt cttctcagag
    17881 aagaacagca tcttattttt cccttctctt tttgcccgct ccagcgcatt atctgcatac
    17941 tgataaatat ttcctcgttc taaattgtca ccccgggtat aggcgacaac tcctgctgaa
    18001 agtgtacaaa agcttgtcaa ttcttcctta accctctggt aaaaggctcg cacatctttt
    18061 tccgttttct ctacgaaatc tacagcaaac tgatccccgt ccagccgata cagtatcata
    18121 tcttcatctg catagttctc cagtaaatct gcaatttttt tcaaaagccg gtttccaaaa
    18181 cttcttccgt tcttcacatt aatatcccga aagttgtcga tgcccagaga cataaaatat
    18241 ccgttttttt cttttaggct ctttctcata tcctcggaaa acttttcaaa attccaaaat
    18301 ccggtgagcg cgtctatctt atgccgcata gcctgttctg aaatgcttcc catcagaaat
    18361 accggaaggc ctgttcgatc tttcaatact gttccgcgac aataaatcca gacttttttc
    18421 ccttcccaat tcataaggcg gtattccata tcatggtttt cactgcatcc tatctgaata
    18481 tcattaaggc tttcttccag ttttttctga tccttgggat acacgatacg gatccacgat
    18541 tctatcggta ttccttccat tcctgatgga atactatact tctcgcatat cttatctgta
    18601 aaatatagtt tcttatttat cagatcatat aagtaaagat aatcatctgt actttcgtcc
    18661 aaaaactgaa ttgtcctcat gtaaattttt cgttcttctt ctaaatgtat caatcctttt
    18721 ccttctttca gaatcttcat tctttttcac tgacgctgtg cccgctccct ggccacaatt
    18781 tgggagctgg ctatttttat tctatcatta taacttaaat ttctctataa aatctttcaa
    18841 aatgtggctt gtattcctaa aaatacacga ttatccgcat accataacac ctaaattttc
    18901 ctaattgctt tcactgtgtc tattctttaa attttactct tgcaatttta atttttttca
    18961 atataatatt gtaaaagaat ggggtgacac atcactgcag cccattaaaa tgtcagcata
    19021 ttagaataaa aatcagggag agtaaaatga aaagaaaacg cttttcacgt gtagactggc
    19081 aggtgtctct gcttctaagt attcttctgg ttttatttgg aatttccatt tttttaacca
    19141 gcagccatat ttgctattat tctattttag acagtcttac gcatcgcgta gaaaatatgc
    19201 acaactatgt ggaacacgaa ctgacgccag aagcattttg ggaaatcaat acaaaagaag
    19261 atatgaacaa aaagagctac taggagctta agaaaatttt ggaaaatgta cgggaacttg
    19321 gcgatctccg gtacttctat accgcaaagt aaagcgcaca ggaagagctg atctatgttg
    19381 tggacggatt atccgaaagt gctgcggact tccgctatcc tggtgacttg attgaaccag
    19441 aaatccagca ggaactgcat gaagctttaa gcggaaaaac cgtgcttcca gacaaaattc
    19501 tcgacactgg ctggggaaat attttcattg cctactcccc tcttcacaat gggcagggaa
    19561 aagtcgtagg cgcacttgga atcgaaatcg cagccgatgt ggaggctgca gctattgatc
    19621 agctgtcaaa agccatcttt gtttcctgcc tgttcttttg cggaatttcc atttttatat
    19681 cgcttgtaat tttccggcgg atttccaacc ctctgtacag agatatgtcc aatacagatt
    19741 ttatgaccaa tctaaaaaat aggaacgcct atgaggttga ccgggataac tggacttcac
    19801 aaaaaacctt aagccagctc actgttgtgg tagttgatct gaataattta aagcttgcca
    19861 acgatcagct gggacacgat gttggagacg cttgtattat tcatgccgct aaaattcttc
    19921 ataaactgga aaaccgcaaa acaaccgctt atcgttatgg aggagatgaa tttattctgc
    19981 tgatggaaga tcagccagat ccaatgcctc tgcttctgaa agcaaaaaaa gaattctgca
    20041 aatatggctc agaattgaaa attcctgtgg ccctggctat cggcgttgcc cagtttgaca
    20101 aatcacgcga tcatacgatt gcagataccc aaaagcgtgc cgacgagcaa atgtaccagg
    20161 acaaattaga aatcaaggct tatgaaaggc agaatataga cagctgtttt agctaaaatt
    20221 ataagcagct tcccattttt catagaacta tcaaaaggag cgaaccgttc tgtttttcgg
    20281 cccgctcctt ttgaatactg attctgtaca ccttttccta tctctccata gcatattcca
    20341 gcgtctgacg tgattgaagt cccacaaacc tctggtattc ctttccatcc ttaaatacaa
    20401 tcagcgtcgg aatgttcata acccccaggc gtcctgccag ctccatctgc tcgctgacgt
    20461 tcaccgttcc cacccggtat ccatcctctg ccatctgctt cacaatcggc agctgcattc
    20521 tgcacggcgc gcaccacggt gcccagaaat caaccagcat agctccttct gctcccacta
    20581 actctgtctc aaaattttct gctgttaaaa tcttctccat atttattcct ttctgccttg
    20641 ccacactctc gtttcatgtt ttccaggact tatgaattag cttttcttaa gattgatttt
    20701 attatacagg aactggcggg aattatctgt gattttatca ccaagtaaca ggttattagt
    20761 gtcgaaacat gacaaaacag tgtcgaagca tcattctttt ttctttaatt tttctgaaat
    20821 atcggttatt tcacataacg aaacctgtaa atatcaatta ttacttatga tacttttgtt
    20881 ttttcatctt catggcatcc tttatgcttt tatttataga caaaagcata tatgcagaag
    20941 gcaggccgta tgtctgatac gctatcaggc aatctaactt atttttggag ggagtggttt
    21001 ttattaagaa tgaagtgaag caagaacaga catttcctaa aattttagtc cttacccatg
    21061 gattttttgg cagtgaactg attaaaagcg ctgaacttgt gatcggaaaa atggaaaata
    21121 cagaatttat acctctgaca agcgatatat ctgtcactgc ctatcaggaa aaagtatttt
    21181 cgcgtctgac acagttaaat gaaaacgata tcgttctggt tgatctgtta ggagggactc
    21241 caagtaatac ggtagctctt ttctccaaac agaaaaaatt cccgctattg caggtttaaa
    21301 cctcagcatc tttatcagct gctctatcaa cagacaggaa aaacgggggg aagaactggt
    21361 tcaggctgtt ttaaaagaag caggaaacag cattcagcaa attaaattgt agaggaggat
    21421 tttcatggaa tataaaacac tggtaatgaa tggggtaaaa caactggaac ttcgcacaca
    21481 tactcttccc gttccggaag caggtcagat tttgatccgt gtaaagagct gcaatatctg
    21541 tacaacagac tggcagaact ggaatggtat gagaggggaa agaagcaaac acttccctta
    21601 cgctcctggc catgaagctt ctggaattat tgaaatggta ggtcctgaag tagagggata
    21661 taaaccgggc gatcacgtat ctgttggttt tacagaatgc ggatactgct ctgactgccg
    21721 ctcaggaaac acaaaaaact gtaaaaatac atctgaaatc catcctcttc ccggcgtaac
    21781 cggcggattc ggaatggctg agtatatgct tctgtttaaa catcaggtgt ttaaaatgga
    21841 agattccctt ccttttgaag aagcttccta cttagaacct ctggcaacag cagtacatgg
    21901 tatccgcaaa atgaatgttc agccggatga cactatgctt gtgattggcg ccggtaatat
    21961 gagaatgctg aacgcccagg tagcccgcgc attcggatgc cgggtattta tcagcgaagt
    22021 aaatgaaaac agaatcagag tcgcctcttc tctgggattt gatgttgtca atcctgcaaa
    22081 agaagatatt acagcttttg ctgatcgctt cagttttcat cagggtgtag atcatgtggt
    22141 tatggcagta ggaaatcagc ctgcagtaga tcaggcattt tcactggtca gacgcggagg
    22201 aaaagtttta ttctttgcag ccggatatcc gtccccatct ttagatcttg acgtaaataa
    22261 gattcactat ggaaactggc atctcattgg cacaggaggc gcgaatgtgg gagattactg
    22321 tctggccagc cagtatctga accacggaac tgtaaaaaca gcacagctga tttcgcatcg
    22381 cgttcccctt gaggattacg aaaaagcctt tgaattagct gagacgcctg gcaattaccg
    22441 cgtttctttg atgccttaat ggagaaagga gaccattatg aatgaaatta ttttatcaag
    22501 agtggacagc cgtctcattc acggacaggt aatgactatg tggtctaaaa caggaggaat
    22561 caatcacatc tatgtggtag atgatcaagt ggcttccgat ccattcatga aagatgtcta
    22621 tttaatggcc gttcccgact ccctcggagt aacgattcac tcggtggatg atgctgtcag
    22681 ccagtataaa aacgggcaga tgccagacgc aaaactgctt gttctaatta aagatgtgac
    22741 gaccgcatat cgcctttgga agcagagatt ccctatggag agcctgcaga ttggcaacct
    22801 aacacctcag aaaaagacaa aaatccttca ccgctccagc cgcctcagcg aagaacatat
    22861 gcctgagctt ttggaaatgc gcagggaagg agtaatggta tatgcacaat cagttcctac
    22921 tgaaaaaaag attgatgtag agacctgggc ataaacgaaa ggagggcggc agatgtttct
    22981 gcaatcttta ctaattggta ttctgtattt tttctgcaga tggaatccat tctatacctc
    23041 ttggctggaa gccagctgca cacctatgtt tctctctgtt atcatcggat ttatcatggg
    23101 agacgtaacc tcggccgtca ttgtcggagc atatgtccag actgtttatt taggtcttat
    23161 cactggttta ggcggcgtag ccactgtaga taaaagtctt ggcagctgta tcattattcc
    23221 gttagctgta gcttccggta tgagtccgga acttgctgtc agcatggcga ttccatttgg
    23281 gcttttaggt actctcacga ttaacctctc caaggttttt tcatcctttg ccgccagccg
    23341 gtgcgacaaa gctgctgaag aaggaaacgc tgccaagttc cggaggattc atctgggata
    23401 tgccgccgga ttctggagta tttttggtat tattccagtt actttgatca attatttcgg
    23461 tccgtctgca gttacctctg ttgtaaatgc aatcccagaa cgtctggtaa ctggtcttac
    23521 agtggctgga ggtctgatgc ctgcccttgg ttttgccatg accgtccgtg tcattggaag
    23581 aaaaaattac cttccattct tcttcctggg attcttcctg gtaaaatatt ttaatcttcc
    23641 atccattgga tgtgctatct ttgctgttat tgcatccatt atctatattc agctgaaggg
    23701 aggaaaggca aatgagcaaa cagcctgata ataaaagcga tcggattcta tcaaaacgcg
    23761 acttgttttt tgcctggttc cgttacaata tgttcggcca tgtagcccaa agtacagacc
    23821 ggcttcaggg cggcggattc tgcgtagcca tcagccgcac gttggaaaag ctttacacag
    23881 acaaagagcg gctcgcacag gcctgaaagc gccatatggt gctttttaac tgcaatgtaa
    23941 actgggccag catcatcatg ggaagtacag ttgctctcga agaagccaaa gcgcaaaatg
    24001 acgacgctgt gcctgaggaa atgatcaccg gactaaaaac aggattaatg gggcctgtgg
    24061 ctggaattgg agataccatt gactggctta ccatatctcc tatccttgtt tccatgtttc
    24121 tccccgctgc gaaagaggga aatttcctgg cagctatggc agaacctatt atttttgctc
    24181 taatttgtac cacaatcggt tacatgctgt tccagcttgg gtactaccag gggcgaaatt
    24241 ccattgccac ccttttaaag ggaagccgca taaagaaaat tattgaaggc tgttccatta
    24301 tgggaatgtt catgatggga tcgatttggg caaactttgt acgagcctct actcctctaa
    24361 ccctgacaat aggaaacgat gtttataaaa ttcaggatta tttcgatatg atcgctcctg
    24421 gtattctccc tttaacagca gtggttctat cctacttgta tctggagcgt aaagggaata
    24481 aatacatgca tgtattaatc ggtcttctgg ttattggagt cgttttaggt tcccttggaa
    24541 ttttataacc agacagtgca ttctgttcac tatacttaat ttgccataat cttaaaacta
    24601 ggaggataaa aaatgctgat agatatgaaa accctgcttg atgaagctac gaaaaaggga
    24661 tactgcgtcc ctgctcccag cgtatttaac gctctcacta tcgaaactgc tttcagcaga
    24721 gctgtaaaag tccattcgcc tgtaatcctg aatgcaggag gccctcttga ttttgaattt
    24781 ctggctgaaa ccgctaaatt ttacagccgg agaaaccctg aagtccccgt tgccctgaat
    24841 ttggatcacg gcgatgattt cgagcaggca atgagagcca tacgcgccgg ttttacatct
    24901 gtcatgctgg ataaatcgtc tgctcccttt gaagagaata taagagaaac aaaagaagta
    24961 gtacatgccg ctcacattgt cggagtatct gtagaggcag agctgggatg cgtcggtttc
    25021 gggcgtttaa gcgatgctgc caaaggaaac atcattgatt ttctttcaga tcacgaccct
    25081 catcagcgcg gcgtctatgg gaaaatgccg actgccggaa tgcagggata cggagataaa
    25141 ttagaggaat atatgattct tttcggctct gcaggccagt ggtaatccag tcaataaaac
    25201 tatttttacg gaggactgcg tatatggaat atacatatct tggacgaacc ggtttgaaaa
    25261 taagccgact ctgtctggga actatgaact ttggtcccag aacagaagaa aaagatgcat
    25321 ttcgaattct ggatatggct cttgatgcag gaattaacta tatcgataca gccaatatct
    25381 atggaagtct gcatggaaca catgaaaata accataccgg atggacggag gaaatccttg
    25441 gacgatggtt tgctcagggc ggacagcgca gagaacgggt catactggct accaaagtct
    25501 actgcaacat gaaggatccc gccgaaggtc cgaatggcga cggcaattca gcttacaaaa
    25561 taagccgcca catcgacggt tctttaaagc ggcttcagac ggatcacatt gacatctacc
    25621 agatgcatca tatcgagcgc catgctccct gggcagaaat atggcctgct tttgagcggc
    25681 tggcaaatca aggaaaaatt ctgtataccg gttcctgcaa ctttgccgcc cgtcatctgg
    25741 tcacagcaca gtatgaagca aaaaaaagaa attttctcgg actggtcagt gagcaggaca
    25801 agtataacct tgtaaaccgc cttcctgagt tggaggttct tcccgccgca aaagaactgg
    25861 ggatcgcatt ccttccatgg agcccacttc atggcggata tctaagcggc acaatgatga
    25921 accgccatgc aggcagcagg ggatccgaag aatttgccgc tcatctttcg gaagcgcaga
    25981 aacagcagtt actgcagtat gaatctcttt gtacagatat tggagaatca caggcagacg
    26041 ttgccctggc ctggcttctg cgcaatccag gtgtgacagc tcctattatc ggtcccagaa
    26101 ctgacagaca gcttgaatct gctctccatg ctgctgaaat taaactgtca gacgatgtac
    26161 tgaaagaact ggatcgcatc tttcccggac caggaggaga ggccccggaa gcttacgcct
    26221 ggtaagtgaa acgcaaaatg taaaacagca caaacaggaa gggaccgaac tggctgtaac
    26281 gcagccgggc agtttcttcc tgttatatgt attcaaggag tggttatatt gaaagaaatt
    26341 attcttgatt atgtcaaaaa cgtaacaaaa gaaaaggatc tggactattt atttaaaaat
    26401 ctgaactcac agtatattgc agataaattt aagataaaga gaaataccgt cagccaatat
    26461 ttaaatgaag ctgcttcaaa ggacctggta aaaatcaata cgcgcccggt tctttttttg
    26521 catcgtgaag aatttatcaa acgttttttc tatctgagca aacagtccta ctctagtatt
    26581 caggagcttt taagtgaaga aaatcaaaat atccaaatcc atgaagatat cttccaaaat
    26641 atcgtaggat ataacggaag cctaaaacgt ccgattgaac agatgtccag ctctattctg
    26701 tatcctgaca acagccttcc cattctgctc cacggacctt caggttctgg aaaaagctat
    26761 ctggctgggc ttatgcatca atttgccatt cacaatcata tacttgcccc agatgcgcct
    26821 tttcatatct ttaactgtgc tcaatatgcc aataaccctg aacttctttc aagcaatctt
    26881 ttcgggcaca gtaagggtgc ttttaccgga gctgtctgcg atacaaaagg cattctggcc
    26941 gcgtccgatg gaggtatcct gtttttagat gaggtccaca gattaaattt tgaaaatcaa
    27001 gaaaaattat ttattttcct tgataaagga atatttcgaa aagttggtga aaatgcagtc
    27061 tggcaaaaag ccaatgtcag aattattatg gcgactactg aggacataca ctcttccttt
    27121 ttagacactt ttattagaag aattcctgtg attgtgacgc ttccctctct ggaagaccgc
    27181 ggaaaagaag aaaagctcca gctgctttcc ctcttttttt atcgtgaaag caaggtatta
    27241 aaaaagcgcg tccttatctc ccggcaggtt atcagcctgc ttttaagctc tgcctttaaa
    27301 ggaaatgcgg gagggcttct cagtgttgtt aaatatacct gcgctaaagc ttattcccac
    27361 agccgaagca atgagtgcat ctgtgttaaa atcagcgacc ttccagagcc tgtgatcgct
    27421 tctgcttcct ttgaacatgg cagcgaaact gattttcaag aaaatcgaat tattcacagg
    27481 aattgatgtt tctttgactg aaactaccga acagcatgcc gccagactgg gagcttacat
    27541 agattatttt caaattcaaa gtgggatcat aatcttttcc gacttgatat ctctggaaga
    27601 actacggctt tctttgatcc agcagctgca aattcctttt atacttgtag gctgtacatc
    27661 tgtaaacaca gtctcatcct ttggaaaagc tctcctttgc cataacagcc atttttttga
    27721 aacccttact ccacaataca gctttccctg ctatattcat cagccgaaac aacgggagaa
    27781 aattctttta gcagtctgtc ctaccggcgg agtttcaaaa aagcttaaaa atattttaaa
    27841 ccaaagcatc cctcagacag tgcctctaag agttatcgat atgccttatg atcaaatcaa
    27901 gctggaggag gaaaagctcc ttcttttaaa gcagtatgag cctatcggag ttattggagt
    27961 catgaatccc tgtatatccg gtgttccttt tatctatctg cacgaattaa cagcagaata
    28021 tgccgaacct aagatctact cgatcttttc ctctgtggca gaaccagagc aaattgctga
    28081 tattgtaaaa aatctcgtca gaaatttgtc tctagatcgc ttgataggca atatcactat
    28141 tctggacggc agtcggcttt taattaatat ctcaaattgt cttgattact atgaacagat
    28201 aacagagcac tctctttcaa accgcatacg ctattgtcta tattttcata ttagctgtct
    28261 ggtagaacgt ctaatccgaa aagaaccgat tactacctgc ggcaatttag aatattttat
    28321 tcaaactgaa cagacggcta tacaaaatat taaatcatcg ttcagcgaac tggaaattgc
    28381 ctatggcatt gatgttcccg atgctgaaat taaatatcta tccgatattc tgctggaaag
    28441 ccattaggtc tctatgcact tttcagcggc ttccatccaa acgcaaagag agaagaagaa
    28501 attttccagc agccttccca tacataaagg aagagggaat gttttcagcg acttccagtg
    28561 gagcgtaaaa acattccctc ttcctattta tctcctcttt atttcttcaa aaatcccgaa
    28621 atcctcttat acagaagaaa ggtcacggct ccgttgattc cggcctttat caggttaaag
    28681 cccacgataa agggcatcag atcccagacc atctctctgg acacgcccat aaacagcggc
    28741 gtgataatca ggttggctcc aagcatcacg gccgccatgc ccatcattcc gagaacgaga
    28801 cctattaccg ccgaagtcct ggtctttctg atgtggtaca cgcttcctga aatcaccacc
    28861 agtgttccgg ttgccagaag gtgcataata attccgtaca gtccgctgcc tgcgctgacg
    28921 gtcactccct gaatcaccga cgtgaccaga gtcagcagaa cgcctgccgc cggtccgaag
    28981 gcaaaggttc cgatcaaaat cgaaatatcc gccggatcgt actccagaaa cgccactgcc
    29041 ggaaaaatcg ggaagtggat caggtacacc agtacaatcg aaatggctac catggaactc
    29101 atcttcacca gacgcagagt ctgtgctctt cctgtctgcg ggtaactagc tgctgtcttg
    29161 ctcatcttca cattcctcct actgaacgta attgtgtatt aaacatgaag aatctgattc
    29221 tgcggagcat tttaccttat gaagctgtgt tttctgttct gctctcagct cataaaagta
    29281 aaaaaagtct tgaaaataaa tttcaagact aaaaaaatac agatctgtat ttttgtttct
    29341 ttcatccgga ctataccgtt ggtatggggt tcccacccat tctgccctga cgcgcagagc
    29401 tcgcggactc gcagcatacg cttatcaccg ccagtgagga atttcgcctc gccctgaaac
    29461 agatttttct actacatcat accatgttcc gggaggtctg tcaaatctgt cctctttcct
    29521 ggatctggcc aaaacgtttt ctcgcgtcgc ggtaggctac cagcagggcc ttcactgagg
    29581 atccgaagta tcttctcctg atttcctcct cgattttctg atcgtcctcc aatattctct
    29641 tccccacaaa catgcgcctt acgaagcttc tggtcagctc cagggttccg gaacagtccg
    29701 cctccacaat ctccccggtc cgtccgttga tttcaaaggc cacataaaaa gctccgtacg
    29761 tctttgtgat ggcgttttcc acgctggttc tcgactcccc tgtcacatac actgtctcgt
    29821 ccttcatttc cctcacctta tagttccctt ctccagctct ttccaaaaag acgccctgag
    29881 atatacttcc ctctcagggc atccagacag agctattata agtcagtctt ccttttgctg
    29941 tcaaggaaag gccggactaa gacaaggcca gactaggaca gggcgtcgaa gactatccgg
    30001 gaaatgtgtc ctatcacttc ccgtccctcc ttattgctct ccatttcact ggtcagaacg
    30061 gtgagaatgt acgggcgtcc cggcaggaat atgattcctc cgtcgttttc cagggcgtcc
    30121 agatctccgc acttatgggc agtctcaatc tcctcgggca gatacagctg aaggcgtcct
    30181 ccctgctgct gcctcctgag aatatccatc atcaggcggc tctcctcctc ccccacgcac
    30241 tgtcccgcgt aaatctgcct gaaaatctct gtcatgtcgt ccgcgcagat gtaattgtcc
    30301 cttccctgct ttttcgcctc ggaatccatc atcaggcggc ccagacaggc ctctttcagc
    30361 ccaagctctg aagccatgcg attcacactg tccattccca gcatccgtat taaaatattc
    30421 gtggcctcgt tgtcgctgac aatgatcata agagtcaaaa tctccctgag agtaaaggta
    30481 tgtccaggca gaagttcctt taaaattccg tctccccctg tcctcatctc ctccgtcaca
    30541 gtgatcgtct gctccagaga cagttccccc tctctcattc tgcgcatggc ctccgccaga
    30601 atgaccagct taatggtgct ggccgacggg acccgctctg tgccgcggat ggaaaagccc
    30661 tccccggcgt tcaaatcata aaagctgacg cagacctttc cctgttttcc ctgaagaaag
    30721 gcgcaaatat cctgcttcat ttctgctatt tttgtcatat ctgccatctc tgatcccctt
    30781 ttctgcttct gacactcatc agccgaacat tgccctgatt cctacgtaaa tcacagttac
    30841 agccgtaatg gtaatgccga atttcaccat attttttaaa tccttggaac gggccagtcc
    30901 catctgtccc atcatgtctg cctccggata ggcaaaggag gtgatctgag aacctactaa
    30961 taaaatcgta gcccagagtc cggtagacat tccaattgct gttaccagct ccttgaacat
    31021 gctgtccata acgaccgact gggccgcagc cgcgccgccg actccgaaaa taccggtaag
    31081 agccgttaca agagctacga tcaccttgct gttggagtga agcagaggct cgataatctt
    31141 taccaaagcg tcgaatgcgc ctgcctctga gacgaatgtg ataaacggtg taaacagcac
    31201 aaacataata aacagccaca tcattttgct ggcgccttca atcatgacct caaacaggcg
    31261 gtcagggtga atgcctcccg ccaggcctgt cacaatggct gtgacggaga taaccagaat
    31321 ggcataggtg gaaccggact gcagataaat gccgtatccg atcatagccg ccatgcagat
    31381 ggcaaacgcc gctgtcgccc gcttcgctcc tgcgcttggc acatagtcct tctccaccgt
    31441 ctcctccagc tcatactggt aaacgccctt tgtctttttc tgaattctgg aagcgcagat
    31501 aaaggtagtc acccagcaga gagccgctac gggaagtccg gtctggataa tgtactggga
    31561 ataggtcatt cctgtcaggg acataatcgt caccacctgc ggagagtacg gcccgatgaa
    31621 aaggcctgta attccggctc ccatcagcac ggccgccatg gtggaagggg taatccctat
    31681 gatagctacc agcggaataa tcatgggcgc aataatggcg ttggcgcctg ccagagagcc
    31741 taacagagcc acaatcacga tagaagtaac catggacgcc agaattgcct ttttttcaga
    31801 gttgattccg atttttttca tcagagtcat aattaaaaac tccgcggctc ccgtctcctt
    31861 taacacggcg ccgagggctg aaccaagcat gataataaat ccgatgattc ccaggaaaga
    31921 tcccagagcg gatcccagca cctctcccat gctggaaaac ggctgtttcg tcataatcgc
    31981 gctcagcacc acgcagatca ctacatttaa aacaggatta atatccttaa acgctaaaat
    32041 aatatagata attaacggaa gcaaagcaaa aatcggtgaa attccaaata tcattgtaga
    32101 ttccatatcg tttccccctt atctgtcctc ttcatcataa acaattccgc tgacgcgcac
    32161 aattcccagt cccggactgt cgtttactgt aatggtcttc tcccggaact ctgcgcctcc
    32221 ctctaccgga tcctcgctgc aaagccccgg cccgtctaaa tcaatcttcg tgataatctg
    32281 tctggcacag gccagatgaa ccgccgcgtt gacgctgacc ttcgcctcca gcatacagcc
    32341 aatcatgcac tctaccccgt agatttcggc cgccgccgcg atctttaagg cgttgtaaat
    32401 ccctccgcac ttcatcagtt taatgtttac cagatccgcc gcccgcatct gcatgatttt
    32461 taccgcgtcc tgaggtgaaa atacgctctc gtctgccaaa atcggaatat ccgcgtgatc
    32521 cgttacgtat ttcaggcctt cgagatccgc ggccttcacc ggctgctctg caaattcgat
    32581 tcccagcccc ttttcctgca tttggttcaa aatactgact gcctgtttcg gcgtccatgc
    32641 ctggttcgcg tcgattcgga tggaaacgtc cgctcctgcc gcctggcgga ctgccgtaag
    32701 acgttccaca tccagcgcag gattcacgcc caccttgatt ttcaggcagt cataccccct
    32761 ctttaccgcc tgcctggcgt cctctgccat ctgctccgga tcgttgacgc tgatcgtcaa
    32821 gtctgtgcag atctgcctcc tgcttccccc cagaagcttg taaaccggga tatggtgcag
    32881 ctgtccgtac aagtcccaca gcgccatgtc cacagccgcc ttggcgctct tgttccccac
    32941 aatgcaggaa ttaaggcgtc tcatcaagtc ttcaaattcg tccacctctc tgcccagaag
    33001 agccggcctg atgtgttcct caatggctcc ccgcacagaa cctctggtgt ctcctgttat
    33061 caccccggtg gagggcgctt cgccgtatcc cacgcagcct gtgttcgtgt ggatctccac
    33121 aatcacatcg tttacatgcg tcactgttct gagcgccgtc ttaaacggcg ttctgagagg
    33181 cactgacaaa agtcctgtcc tgatctgtgt gattttcatt cgttctctcc tttcccctga
    33241 aagcaaaagc tgccggcgca catgataagg tatttttatg cggcagagcc ttatcctgaa
    33301 atacaagaaa gattcctgcg gagcattttt tatttcatag gacgcttttt tcctgtgaaa
    33361 caagaacgaa ttctgctctg cagaattctc cgcctgcggc gggctgctca gcagcataat
    33421 accgcaccgc cgcagtgcga ttcctgcgga gcttttttta tttcatagga cgcttttttc
    33481 ctatgaaata aaaaaatacc cagcccaaaa acaggtacct gttcttggct gggtttcatt
    33541 tgctccgaac tagcggtgtg ctatttcaca caaaatgaag cagcttttcc attactttca
    33601 ttttatcact tatttgattt gttaattatt ataatatatt cattgtaatc agtcaattca
    33661 tttccgattt tttcccattt ttcctatttc ttctgaaaaa agcctctaaa aaccgcaaga
    33721 cagctgctgc cctgcggttc tctctgcttt ctattacgaa ttaaaactgg ttgtggctgt
    33781 tttccttttt gaagcctctg ctttttgctg ttttagcggt accactgaat aacaggaatt
    33841 ctcagctctg cgcctccgtc gtagtaaaaa tctcccactt ccttcagctt gtagccttcc
    33901 ggcacgttgg tcagctcgct ggaatttacg ttgccttttc cgtttacaag acctgctgcc
    33961 cagatttctc cgttggccca cacgtggttg gtagcctcgc agtaataaac tacgttgaca
    34021 tagccgcctc ttgtctcctc cggaactacc tggattctca gctctgcgcc tccgtcgtag
    34081 taaaaatctc ccacttcctt cagcttgtaa ccttccggca cgttggtcag ctcgctggaa
    34141 tttacgttgc cttttccatt tacaagacct gctgcccaga tttctccgtt ggcccacacg
    34201 tggttttctt ccttacattc atagaccaca ttgaccattc cgccctttac cacattagga
    34261 actacctgga ttctcagctc cgcgcctccg tcatagtaga agtctcccac ttccttcagc
    34321 ttgtagccct ccggcacgtt ggtcagctcg ctggagttta cgttgccttt tccgtctgca
    34381 aggcctgctg cccaaatttc tccgttggcc cacacggtat tatcttcctc gcagaagtac
    34441 acgacattga caaaaccgcc gacagctgga cggtgctcgc cgtcatcatt tccgccgttt
    34501 cctccgtgat gatggtttcc tccaccccag tggtgatcgt cgtcatcatc gtcatcatcg
    34561 tcgtcccagc gatcatcgtc ccagcggtct tcccatcgat cctcccagtc gtctccgtgg
    34621 tgaggtctcg cctgagactc caggacaccc atctggcttc ccgccattac aagcgctgct
    34681 gcaaacaata aacctgtgat attacgtttc ctcatataga agccctcctt cttaatacat
    34741 ttccgtacat ttcgtttttg ctttgctatg agcagattat aggtaatttt caaataataa
    34801 tcaatagact tcataaagga gtaagaaaac gtatataaaa tgtaaatatg gcagaaaaat
    34861 gtaagaaatt tctatctttc tctccgctcc ttctcctcct cgaattgtaa actatttcat
    34921 ttttttagtt gacattttac accgatatgg tattatcttg aatgagctca gcgtctgcgc
    34981 tcacagcata ttgtctctga tacgcggacg ctttctatat acagtttcag attccggcat
    35041 gcagaatcac caagtcagga ggaccgattt tgagacgaga aaagacgaaa gatatgattc
    35101 tctgcgccat gtttgtagct ttaattgccg caggcgcttt tattaaaatt cccattccag
    35161 tcattccatt tacgcttcaa tatctattta ccatgatggc aggactcctg ctggggccga
    35221 aaaaaggctg tctggccgtt ctgatctaca tccttctggg gctgatggga cttcccattt
    35281 tcgcccaggg cggagggatc ggctaccttg tccagcccag cttcggctac ctggccggct
    35341 tcgccgcagg cgcgtatgtc acaggtttcc tggctgaagc ggaaaaatat ccgggaatcc
    35401 ggcggcttct ggccgctgac tttgccgggc tggggattgt atattccctg ggcatggcct
    35461 ggtactggct gatcagccgg ttttatctgg gaacgcccat cgggctttgg cctttgtttc
    35521 tctactgctt tctgttagcg gttccaggag atattctcct ttgcatagcg ggagcctatt
    35581 taggaaaacg gctgattccg ttggtaaaaa gcggaatgat ttaaatacga ggaggtctga
    35641 ttatgaataa atctctgttt atcatcggca cgggaacaga tgtgggaaaa acctacgttt
    35701 ccggcctgat tctgaaaaaa ctgcgggaga gcggcgcttc tgccgcctac tacaaagcag
    35761 ccatgagcgg aaacgaacgc ggcggggacg gcgtcctgat tcccggcgac gccctgtggg
    35821 taaaagagca ttccggcatt gcccagccgc tgcaggaaat gtgtcccttt gtctatgaag
    35881 cagccgtttc cccgcatctg gccgcccgcc tggagggcca tccggtggat cttgacactg
    35941 tgatgagcgg tttccgttct ctcagaaatt gctgtgaata ccttactctg gaaggttccg
    36001 gcggcgtcct ctgtcctctg cgttttgacg gacaggagct gtggcttact gacgtgatcc
    36061 gctcctgcgg ttccggatgt cttctggtgg cggacgcagg cctggggacg atcaatcagg
    36121 ccgggctgac cgccttcttt ctgaaacagc agaagctccc tctgaaggga gtgatcttaa
    36181 accattacca gccgggaaac gtcctgcatg aggacaataa aaagatgtgc gagtatgtga
    36241 caggcgtaaa ggtcgcagcc tgcgtccagg atggagacaa ggacctgcgc atctctgccg
    36301 gcgatctgaa agcgctgtat gaggaggaaa taaaatgatt tggtatccct atgagcagat
    36361 gaaaaccatg gccccgccga tttccattac cggagccaaa ggagtctatt tgtataccga
    36421 aaaggggaaa atgattgact ccgtatcctc ctggtggagc gtaatccacg gctacaatca
    36481 cccggagctg aaccaggcca tgatcgacca ggtcggccga ttttcccatg tgatgttagg
    36541 cgggctgact catgaaccgg tccagcggct ggccggcagg ctggaagagt ttctcccggg
    36601 agatctgaat tactccttct tctctgattc aggaagcgtg gctgtggagg tcgccctgaa
    36661 aatggctctg cagtattaca tgaaccgggg cgaaacggag cggactctga cgctggctct
    36721 cgaacacgcc taccacggcg atacctttaa aaccatggaa accggagacg acgaggatta
    36781 ccactttgtc ctgaaggcct acggccccag ccgccacgtg atccacattc ccaccgagat
    36841 tcctgccctg gaacaggcct ttgagcagta tcacagccgt ctgaactgtc tgattgtgga
    36901 acctcttctc cagggagcgg gcggaatgcg catgtacagc ctgtcctttt taaaacgcgc
    36961 cagacagctg tgcgatcagt acggcgttct tctgattttc gacgaggttg ccaccggatt
    37021 tgggcggacg ggaaaccgct ttgtatccga tctggttctg ccggatatcc tggttctcgg
    37081 aaaagcgctg acaggcggct atatcggcca tgccgccacg gtcgccaatg agaaggtatt
    37141 ccgcggcttt tttgacgacc agccggaaca tgctctcatg cacggcccca cctttatggg
    37201 aaacgccctg gcctgcagcg cagccctcaa atccatcgag ctgtttgaaa cccaggacta
    37261 catggccaaa atccgccgca ttgaggccat cacgaggaga gagctggatg gcttctctga
    37321 cgacagaatc agagaaatca gaatcatggg aggctgcgtc tgcatcgagg tgaaggacgc
    37381 atccattctg gagggatatc agaagttcgc cagagaacgg ggcgtattca gccgcccgtt
    37441 tctgaattac ctgtacgcca tggtccccta tgtaatcgca gaggaggagc tggttcaggt
    37501 gatacaggtg atgaaggagt ggttcagaag gtaggccggg ccgctctgtc tgctgagaag
    37561 tctggctctt gaccgcattt ctttttcatt gcaaaagtac cctgtcaatc gggcacaatg
    37621 ctttttgcgc caaataaaca gggtactgtc tgcttttttt cagtttatta tgcgtttgct
    37681 ctctttcttc caaagaagat aaatccggct gctgcgaatc cgaccataat ggccacgccc
    37741 acgccgaagg ttaagccgat accgctcatc agccacatag gagccagtcc tacgaacacg
    37801 tccttccagg acataagagc ggaatatact ccgtgtgtat ctccggcgct gcactgagac
    37861 tccggatcca cggctcttac aagggcaagt cctgtagagg tatttccagt cgctgctccg
    37921 aacgccatgc aggccttctc aaaccactcg tctctgcaga agcggcgggc aagaccgaaa
    37981 ataatcggaa ttgttaaaat acttaaaatt gcagtgtaaa ttaaaacagg tacaatgtag
    38041 gtggagataa actccagatc cagggttgcc attgcggtga acaccgtgat ctccaggcag
    38101 aatccgccgg ccatcttgat cgtctttaag tccacgaact tgtctaactt tgtaagcttt
    38161 aagatatacc acagaatcgc gcctccgaag ataccatgaa gcacgcttgg cattcctgcg
    38221 aaaaactcag agaaggaacc caggaagccg aacagctgac ggccaataaa cagagctaat
    38281 aacagccagg acacctagag agccagatgg ttgatgctga tactggtcgt taccgtgtgg
    38341 ccggaagcag ctctcttctc ttttggaagt acgccgccgt agaaataatc cggctgcttc
    38401 tgaggctcct tcacataggt tccccagccc tttctgattc cgtagttgac catgatcata
    38461 cctaccacca tggctaccac aaggcccaga gtggaaagaa ccatgcctac ggacatattt
    38521 cccggaacgc ccagcttgtc aaaggtggct gctgccgctg ccgccgtacc gtggccgccg
    38581 tggaaggcaa atacgcccat gatgccccat ccgtccggaa gtcccggcca gatcttctga
    38641 agcacgaatc ccagaagaac gcccagagcc atctgcatac cataagaagt catggtcata
    38701 cagctgtaat ccagatagga acccattttc ttgcggttaa tagtaactcc gaatacggtt
    38761 gtcgccatta caatatcaat cattacgctt ggcatggatg aaaaactttc cggcacgttt
    38821 acaacgccgg cgatctgcgg gccaaggatc agaagaacga ggccgccgat taaggatgat
    38881 gacaggaata acttctggag tggctttgca atctcgcgga caaaaaagcc gaccagcata
    38941 aacactgcca ggattaacat gtcatcacaa aaagatgcaa ctgtcataac gctttcccct
    39001 ttacatttga taataaatcg ttattttgat caaattaacc tgatttgtta tgactgtatt
    39061 gtaatatatg tctaatcaca aggcaaacaa tctatttttt taatttcgac aattttttct
    39121 tgttatagaa ctggataatg ctgattctgc ggtcgggtct ctgcaatttt ttccaatacc
    39181 tgctttgtta aactaataaa atccagggca taatccggca gaaaacgctc ttcatggtac
    39241 gcggctacca ggcggtgctg aaccggctcg ccgttcatga acaggggaaa tgcgttggcg
    39301 tccgggtgca tggctaaaag cgtgggcata cgcatctggg tacagaaaaa agccccgtaa
    39361 tcataggcgt acagagacat gtacagctcg atcacctggg tttcaaattt aatttcagga
    39421 acgactcccg cctcctgaaa gcactgatcc acaatgcggc gaagcttcat aggcgctttc
    39481 ggcatgagga acggaacctt ggcaaattcc ttcaaatcga cgccggaaag cgattccctt
    39541 tttaccttct cccaggaatc aaaaaagtac tgctggagaa gcctgtcaga gcagaccaga
    39601 tagatctgat cgtttaaaat cgactctatt ttaagcttcg gcttgtcctg atacataatt
    39661 ccgataaaga gatccagctc tccgtcaaat aattttttct ccataatacc ggatgattcg
    39721 cttaccaggt caatggagac gttgggccat ttctcataga agggaggcag gatctccgga
    39781 aggcagatct ggccccggta gccgggaatt cccaccttca aatggccttt tctgtttgtg
    39841 gaaatattgg aaaggcggtt aatcagctcg ttttcttccg ccaggatttt cgtcgctacg
    39901 gctaacagct gctctccggc gtaggtgaga gtcattttcg gcttcctgtt aaacagggtg
    39961 acgccgtaat actgttccag cttctggatg tgctggctta aattctgctg ggatatgtag
    40021 agcttctgcg ccgtatgagt cacatgaagc tccttggcca attctacaaa atagtaaaga
    40081 ctctgcaaat tcatatggat tcctccgctg gcatcgtttt tcaggattct tcgtgtcagt
    40141 gtatactgac gctatctatt cttctgcatt ttttgttggt tcctgtcgtt tcttatgatt
    40201 attataagag aaccgcggct ctgtgtaaat aagctgacaa caatattttg ttaatatgat
    40261 aaaaaagtgt tgtttgcttt tgtgcttttt ctggactaca atgaagacaa tgaaaaatga
    40321 atctccaaag atatgaatct acgaaaggaa ggtatattgt tatggcagta ggaaagagaa
    40381 tttacctgaa aagacacatg ccggatccgg aggttatgat gcagttcaag acgatcccgg
    40441 catctaacac aggcgacgtt atgggaagaa acgcagctat gaatccgaga atcaagctgg
    40501 tgaacagccc taaggatcag atgatggtag gcccggccct gactgtaaaa gcaagaggcg
    40561 gcgacaatct ggctcttcac gcagctctca atatcgctca ggaaggcgac gtattagtag
    40621 tttccaacga gggcgacaac acacgcgctc tgatgggcga gatcatgatg gcatatctgc
    40681 gccatacaaa aaaggtagcc ggcatcgttt tagacggacc aatccgcgat atcgacgaga
    40741 tcggcaaatg ggatttccct gtatatgcga caggcactac tccaggcggc ccatacaagg
    40801 agggaccggg cgaggttaac gttccgattg cctgcggcga ggtaagcgta aatcctggcg
    40861 acatcatttt agcagatccg gacggcgtaa tcgtaatccc gagaaaggac gctccgcaga
    40921 ttttagagga cgccaagaag ttccaggcag ccgacgagag caagctcgta gcagctacaa
    40981 acggcacagc caacagagcc tgggttgata aggctctgga agcaaaagag ttcgagatca
    41041 tcgacggaat ctacgagcca taaagcggtt tttgttctgc cccctgcatc aagaaacggg
    41101 agaaactttc cagcgacttc aaattggagc gcagaaagtt ttctcccgtt tctctatgtc
    41161 tatgcttttt ccgtataatg gtgggcttct tccagcatca tatcctttac cttcatcaga
    41221 cgaatctgcg tacttctctc attttcatcc agcttcatgg taatatactt gatattcttc
    41281 tgtgtttccg gaataatcac gtgttccaga gcgtttaccc tgcgcctggt cttctctatc
    41341 tccgaagcca tcagctggca ggatttctcg gtctccgcca gcttcatcat ctggggaagc
    41401 acgtcctgaa gggacttcac agctccgtcc aggtcgctgg aggtgaaggc aaatccatat
    41461 gggtaaatat cgttttcatc cgccgtcctg gttttatacc tgaacacagg aatgtccacg
    41521 ctcatcacgt ttttcttttc cgcttccaga tatacctcct gcttgggggc gatgagggcg
    41581 gcgttcagag cctggccgct catccccgcc ttggcgatga caaagtttac gttggcgctt
    41641 ttaatccccg cctccacctc ctgcctgagg gccatatttt tcttcaccag atcgaggaac
    41701 tggcgcatca gctcatcgcg tttgtccttt agaagcttat gtcccctgac agcggtagcc
    41761 agctttttct taagccttgt aagctccatt ctggtggggt ttacctgagc ctgagccatg
    41821 catcacacct cccctattcc tttccgtagt acagatccag gaatttatcg tcaattctct
    41881 ttaactcact tctgggcaga atagacagaa gcttccagcc gattttaagc gtctcctcaa
    41941 tgcttctgtc cgtctcgtag ccctgggaaa cgtattcctt ctcaaaggcg tcggcaaatt
    42001 tcgcgtagat cagatccaca tccgacagag ccgcctctcc cagaatcacc atcagctcct
    42061 tggcctcctt gcctctggcg taggcggcga acagctggtt catggtattg gagtgatcgg
    42121 ctctcgtctt gccctctccg attcccttat ccttcagacg cgacagggac ggaagcacgt
    42181 caatcggcgg cataacgccc tttctataca gctcgcggct taaaataatc tgtccctctg
    42241 taatgtagcc tgtcagatcc gggatgggat gggtcttgtc atcctccggc atggtcagaa
    42301 tcggaatcat ggtaatggaa cctgtctttc cgttctgtct tccggctctc tcatagatag
    42361 aggccagatc cgtgtacata tagccaggat aaccgcggcg tcccggaacc tcttttctgg
    42421 ccgccgagat ctctctcagg gcgtccgcat agttcgtgat atccgtcagg ataacgagaa
    42481 cgtgcatatt tttctcaaaa gccagatact ctgcagccgt cagggccatc ttcggggtgg
    42541 cgatacgctc caccgccgga tcgttggcca gattaatgaa aagcaccgtc ctgtcgatag
    42601 ctcccgtctc cttaaagctc tcctcaaaga agtgggcttc ctcaaaggtg atgcccatag
    42661 ctgcaaacac aacagcgaag ggctcatcgg ttccccgcac cttagcctgt ctggcaatct
    42721 gagccgccag attggcgtgg ggaaggccgg aggccgagaa aatcggcagc ttctggcctc
    42781 ttaccagcgt gttcagtccg tctatagcag acactcccgt ctggataaac tcctgaggat
    42841 agcttctggc cgccgggttc atgggaagtc cgttgatgtc ccttctctcc tccggcagaa
    42901 tctccggtcc tccgtcaatg gggcggccca gaccgtcgaa cacgcgtccc agcatatcct
    42961 ccgatacgcc cagctccatg gttctcccca ggaaacgcac cttgctgtta gacaggttga
    43021 ttcccgtaga gttttcaaac agctgtacca gggcgttgcc tccgtcgatc tccaacacct
    43081 tgcagcgcct tgtctcgccg tttgccagct caatctcccc cagctcgtcg taggtaacgt
    43141 tctcaacgcc tctcaccagc atcagagggc cggctacttc ctgtatggtt ctgtattctt
    43201 tcggcattta gaagtcctcc cttctgagca cgtcggcaat ctcagcttcc agctcctttg
    43261 tcactgcttc atattctgtc tcaatgtttt catccagcac atatttaaaa cgtccgattt
    43321 tttcgcggac cggcatttta atcaggccct ggacgcctgc gccgtccttc agcgccttct
    43381 cggatttctc gtagaaggcc agaaccagct tcatcatcag gaactgcttt ctcagggaag
    43441 tgtaggtatc cacgtcgtgg aaagagttct ggtgcaggaa atcctcgcgg atggaacggg
    43501 ccgcctccat cttcaggcgg tctgtgggcg acagagcgtc catacctacc atctttacga
    43561 tctcctccag ctccgcctcc tcctggagaa ggctcatcat gccctgacgg caggtcatcc
    43621 actccggaga caccttttcg ttaaaccatt ttcccatatt gtccacatag agggaatagc
    43681 tggtcagcca gttgatggcc gggaaatgtc tcttataggc cagggaggaa tccagtcccc
    43741 agaagacctt gacaatgcgg agggtggcct gggacacagg ctccgagata tctcctcctg
    43801 gcggcgatac ggctccgatg gctgaaagag cgccctccct gccttccgaa ccattgcaca
    43861 ccacatggcc ggctctctcg tagaactggg ccagacggct tcccaggtaa gcgggatagc
    43921 cttcctcgcc gggcatctcc tccagacggc cggacatctc tcggagggcc tccgcccacc
    43981 gggaggtgga atcggccatc agcgccacgg agtagcccat gtctctgaag tattctgcaa
    44041 tggtaattcc cgtatagata gatgcctctc tggccgctac cggcatatca gaggtgttgg
    44101 caatcagcac cgtcctctgc atcagggagt ggcctgtctt cggatccttt aactccggga
    44161 actcgttcag tacgtccgtc atctcgttgc cacgctcgcc gcagccgatg taaaccacaa
    44221 tgtcagcctc cgcccacttg gccagctggt gctggatgac tgtctttccg cttccaaagg
    44281 ggcctggcac cgcagccacg ccgcccttgg cgatggggaa gaaggcgtcg ataactctct
    44341 ggcccgtcac aagaggcatc tcaggaggca gctttttctt gtaggggcgt ccctgtctga
    44401 ctggccagcg ctgcatgagc gtcagctctc tgtcacctgt ctctgtggcg atcaccgcca
    44461 cagtctcctc cactgtaaac tctccggccc ggatctcctt caccgttccc cgcactccgt
    44521 ttggaaccat gatcttatga actaccacaa tggtctcctg gaccgttccg ataatgtccc
    44581 ctgcttccac cgtatccccg gctttcactg taggaacgaa attccacttc aggttcctct
    44641 tcagggaagg aacctccacg ccgcgcttta ggttattgct tcctgtggcc ttcataatgt
    44701 cgtccaacgg acgctggatt ccgtcataaa tactggtaat cagtcctggt cccagctctg
    44761 ccgacagcgg catgtccatg gactccaccg gctctcccgg tcccagtccc gaggtctcct
    44821 cgtaaacctg gatatatgcc tgatccccgt gaatctctat aatctcgcct atcagacgct
    44881 ggctgctgac acggaccacg tcgtacatat tggcgtcccg cattccctct gcaattacca
    44941 gcggtcctgc taccttttta atcacacctt tgctcattgg aaggcttcac ccacctttct
    45001 gtcaactggc ggccaaaggc cgcccttttc actctgctag actcctccga acagaatgtc
    45061 tgatccaacc gcctgttcca ccgacttttt cactccctca atccccttgc ctgtatttcc
    45121 agacactccc ggaatgagga tgaccgccgg aagcaggctt tctctgtacc gctccactgt
    45181 gcggctgatt tgggcggccg ccgcttctgt catgtaaatc accgcatacc cgccggaaac
    45241 aagactgtga aacacctgct caagcttctc cggcccgtct gcgggaaacg tgtcaagtcc
    45301 cagggcggca aagccgtaaa tgctgtcata atctcccacg actgccatct tatacataca
    45361 tttccctgat cctttcccgg atcgcttcct ccggaagatt gttaagcttc ccagtcagga
    45421 tgatccgaac cgtcttaatc tcattttccc tggctaacag gtaggccgcc agcggccccg
    45481 ctgaaaacgg attatatttc tgcggcttaa tgctctctat cagctggttg tcgcaccacc
    45541 tctcaaaggc tgagggcgat tccttgagcg cttccgcccc ttctttgtag gaggttccct
    45601 ccagatattc gcagatggca gaaactcctg agagggccgc catggaaagc cgttccgtat
    45661 tcaggctttc gcagggcgcc atgctctgcc gcataaactc caggctcttt cccgtcttct
    45721 gggaacggac ggctatctta atatccgcca ccgctgtgac tgactctgcg taagccatca
    45781 gcaccggctc gccgctcctt tttccctcgc tgtaaacggc ctctaacgcc gcccggtcca
    45841 ccatggcatc gcagagctgt ccgtctcctg tgtggcggaa ggtctcgtag gcttcctttg
    45901 caacgctctg catgtgctcc gggagagcct tgaaatcctt ttccgccaca atccgctcca
    45961 tctctgttcc gtccacgccg cagccgtcgt agtacagctc tccgggaaaa tcaggcgacg
    46021 ctgtcttttt gatggcggct ttcagattat ggtacagctt ctgataactg aacactgaca
    46081 gaatcctgtc gtctcctccc aggagatccc tgactgtctt ctgcgccttc gcctcctcgg
    46141 cttccagcat ctcctccgct ccctcgttca gatttccgct tccccagccc ttctccctga
    46201 gaaaatcaag gcagccggac cacgttttca ctgccatcag ctgttctatc acagaggagg
    46261 aaaacagcgc cgtttccata gcccggatcc gggcgactgc atacgtataa ttcttatctg
    46321 ccatgctcct ccctcctatt ctttctcaaa caagagcttc tgaatctgat cggagcattc
    46381 gtcccgtttc gccgccagaa gcgcctgaaa ggaacagttt tcctcgattc cgtcataatc
    46441 caggagaaat cctccgtcca gggaagctgg ctccacgcct attttcaggc tccctccacg
    46501 ctctgcggca gcctgttcca ggcgtttccc aaactgttcg ggaagccgtt tcaaatctct
    46561 ctgcgagaag cagatttctc cctctttggg aagcgcgaac cggcggacca tctgctctat
    46621 cagagaaaaa tattcctccg gctccatcgc taaaagagtc tggtgagcct tctcaatctg
    46681 ctcccggatc atatcctgct tggcggccag aatcagctgg cgctttttca gagaggcgga
    46741 ggatctggcc cttgtctcca gctccttttt aacaagcgct tccctctcct tcgcctcctc
    46801 ccggagtctt gaaagtcttt tctccgtttc ccgcaggact gcgccggcct cctcctctgc
    46861 cttctcccgg atttcgccgg cctgcgccct ggcttccgcc agaatccggt ctgtaatctt
    46921 ttccagtccc gtcatatccg tctctccttc catgctctgt attcctgtct cctgcgccct
    46981 gttctctgtc agaaaattct gactgccgaa attaaagcgc gctgactgcc aggatggata
    47041 ctaacagagc cagaatggcg taagtctcta ccatggccgg aaacagcatg gccttaccga
    47101 actgctccgg cttcttagcc acgattccga tggaagctac cgctgtgcgt ccctgatgaa
    47161 tcgcagatac cagacctacg attccaatgg gaaggcaggc taaaaagtac agaaggcctg
    47221 tggctaagga catattcatg tcagcgcctc cgcctaacag tcccgttccg gagagtacca
    47281 gaaagcctac taacagtccg taaataccct gggtaccggg aagcagctgt aaaatcagaa
    47341 ccttggcaaa ttttcccgga tcctctgtca caacgcctgc cgccgcctgc cccgccatgc
    47401 ctactccgat agcggaaccg atgcctgcaa gccctactgc cactgccgcg cccaacaatg
    47461 caaatacaat acccatctca ctcataactt agtcctcctt aatatccgca tattttgtat
    47521 ttctgcgaaa cggctcaaac atccgtccgc cgccctcata aaactttccg aaaaactcta
    47581 catactgaag acggcaggtg tgaacgtaag ctcccagcag attgatcgcc agattaaacc
    47641 catgtcccac cagaaatacc aggataaaca ctactgcgcc caggatgccg tttcccgcca
    47701 tgcttcccat ctggttgata accgaagcga tcacgcctgt ggccagtccc agggccagaa
    47761 gcctggaata ggagagcaca tcggaaagcc agcttgtaat attgtagaga tcatatgctc
    47821 ctaacgccag cctgagagcc ggatttttgc tgcttctgcc tgacatgaga agaattccgg
    47881 ccgctcctcc tatggctaat accttcgcca gcagattgac cggttccggg aatacaatag
    47941 tcatctgaga catggatgca aacagctccg acgggagaag aattaaaata aggcccgtta
    48001 agagacagta ccaaagaacc acgtcacaga agaaatccag aatccgttta tcctttaaca
    48061 gcatatatcc cttcagtccc agtcccagaa acaggtggat cacgccgaac agcatggaca
    48121 tcacaagcat cttcatggga tcgtcaaggg gagtaaacca tacggccggt atgcttattt
    48181 cccgtccgaa aaacgtcctg gaaatcacat tcaccgcatc tccgaaatat ccgccgaaca
    48241 tgacgcccca gaataatgtg gagacgccgc agtacataaa caggcggatc gactttttca
    48301 ggccgcttcc catccttgga aacttcttca gaagaatgaa gcaggccaga aatacaatca
    48361 ggccgtaggc tgcgtccgac agcatcagcc cgaagaaaaa cacgtagcag agcgacatca
    48421 ccgaagtggg atccatctct cctctggccg gaagcccgaa ggaagccgtc actccctccg
    48481 ccgactctgc aaaggtactg ttctttaaaa gcaccggcgc ttcctctgct tccggcactt
    48541 cctctgtctg tacatagaga gcaaatctct cgtttaaacg ggacaaaagc ttctcttcct
    48601 cctgctcagg cacaaagcct gtaagaagga gcgttttccc cgactgaagc atattgccca
    48661 gcgcctggta cttctccgcc cgcatccggc agtaatccga cagcagcctg atattctccc
    48721 gggacgtgcc gtaggctctg agcttttcct ccacagccct gatttcatca cgaatctgcc
    48781 ggatctcctc ctccagctcc tgcttcttca ctgcaggaac ctggtcaaaa ctctgagaag
    48841 gctttgcaaa gcccgcagct ctcagagcct cctccacctg cgccccatcc tctttcaggc
    48901 agagaaccgc ggcgcatacc tgatccttat cctttccgat cagctgaatc gaaacgtccg
    48961 ccgagggcgc tctctcagcc accgcctgat agagagagtc aagcgtcgtc tgcgctcctg
    49021 ccgctccaat aaaaagaacc gtcctttccg ttccggaaca ctgcatggac acgtcgagag
    49081 ccagccacgg ggacagagac tctatctgag cttccagctt ggcaatggcc gccctgctct
    49141 cccctatctt tctgctgtac tctaaaatct gcttcacgtc atccatgatc agctgacagt
    49201 tttcctgaac agctgcaaat tcttctccgg aagccagtgg ctttcccgca agccctgaaa
    49261 gaagagaggt cttttccgga gcatactggt caagaacctc cagggcctgt tccgccgtcc
    49321 atgcgtccct ctcgcagctc tgccgcctgg cagacgtatc cggtctctgg aaatcgcttc
    49381 cctccggttc ctccagccgt gaaatctcca caactccggc tccctgaagg aaatccagca
    49441 cctgtttccg atccgttaaa agagcgcaga tggtaatttt cttcatctgc agaactgcca
    49501 tatccacatc cctcctgtct ggattttctg cggtgtctgt cacgtcttaa gcaggatgtc
    49561 tgtaatcaaa cgtactgctt cctctgattt ctcctccgcg cgctttcgca tcagggaaat
    49621 ctctgcctct gcttctctcc cggcctctga aagaatctct tcttcctcaa gcttagcggc
    49681 gtttcttacc gcctccagac tttcccggat ttcccgttcg gcggcctcgc ttctgctctg
    49741 cgcttccctt cgtgtctgct ctgccagttc ctttcccttc tgtctggctt cgcttaccag
    49801 gccagacgcc tgcgcttccg cttcctgcac cgccagaatc gtttccttta ccattcgctc
    49861 accaccttct gcctctgatt tccagctgtt ccagctcaaa ctcccgcccg gcggctcctg
    49921 tcctgctctt tgtctgccgc cctatgcaaa atgcctgtct caagcttttt cacttgtctg
    49981 cgcctcatat tagtatagtg cggcagcctt ttcttcattc attaaaagaa gcagttcatc
    50041 tcacatattt ccaaatatta tacagcttct taacacatct gtctatgata ttaatttttt
    50101 aatttattat tttcgttttg tttttattgt tttaatattt ttgtcaaaca tttgtgacat
    50161 ttttgtttct tttgaaagta cattgtccag gagcagagga agattccctc ccgcaaaatt
    50221 gtcttttatt ttcaggctct ttgcggtaaa atgtgtgata atagctggtt cagaatcatg
    50281 cgccatacgc ggcggcgggg ttttacggag ggattaaatt gaaacggatt gtaattatta
    50341 cagatcggaa gcggattgca gaaaaaatca gggaggatct gctctgcgtc ttccggggca
    50401 aggcggagct tgagacgctg acctttgagg agattgcgaa gatggaaaca gtcgacggag
    50461 atcttctcct gttcactttg ggagatcgga tcgagcggat caaggaaaag ctccttcacc
    50521 tggaaaatat tgttgtaatc aggcggacaa tcagggagaa aaatctagta aagctctttg
    50581 aaattcctca gggaactcct gtccttgtgg tcaatgacaa ttatgaaaat acgctgcaga
    50641 ccgtcaatct gctctacgac ttaaacgtgg acaacctgat tttaaagcca tggaacggga
    50701 cagacggcgg agacgacatc accatcgctg ttactcccgg ggaagctgaa cgcgttcctt
    50761 cctttattaa gcggatcatt gatatcggag accgctgcgt cgatctggcc acctttatgg
    50821 acattatcta ccggctccag ctgggcggcg aggaaatctc aaagcgcctt ctgtcctatt
    50881 ccgacggaat cgtcaattcc aaccggggac tgaaccagta ttataaagaa acgatcatga
    50941 aaaatattca gatgaagcac gtgctggaat cagtagatct gggcatcctt ctgacgattc
    51001 ccgacggcac tatcgttttg tgcaataagc ggttccgaga aatgatcaaa aagccggtcc
    51061 gtgagggcgt gacgcagctt tcctcccttt tcgacgaatc ccttttcgat tttttctcca
    51121 gagactcctt tgattttgaa ccggccaggt tcggcgtctg cgaaatgaca gtcaggaaaa
    51181 gcaggctaaa ctacgacagc tccgtctatc aggatctcta ttttttccgg gatattacct
    51241 atgtcaaatc tctggaagaa aaaatcagcc gtcaggcgaa aacccagggc ttcactgcca
    51301 gatatcagat acaggatatt ctgtaccagt cggattccat gaggcgctgc ctggagagcg
    51361 tgcgcatctt ttcacctgga aacaaaacca ttctgctgga gggggagagc ggaaccggca
    51421 aggaactgat tgcccagtcc atccaccgcc tgtcagatcg cagcctgcag cccttcgtgg
    51481 cggtcaactg tgcggctgtc cctgaaaacc ttctggaaag cgagttgttc ggctatgtgc
    51541 gcggggcctt caccggggcc agccgggacg gaaaaccggg attgtttgag caggcagata
    51601 agggaactct ctttctcgac gaaatcgggg atatgcctgt aggactccag tcccggctgc
    51661 tgcgcgtgat tcaggaaaaa cagattatga ggatcggaag cgaccgggtg atcaatatag
    51721 acgtccgcat tatcgccgcc actaaccggg atctgcgcca ggagatgaaa cgtggacagt
    51781 tccgcagcga tctctactac cgtctaagtg ttctgcctgt ttctgtgccg cccctgcgtg
    51841 agagaaagga ggacatcctt cttctgtttt ccagcttttt gtcagcgccc tgcgacgttc
    51901 cggagcgcgt ccggcgtatt ctccttgccc acgactggcc cggaaacgtc agggagcttc
    51961 gcaatgccgc cgaatacttc gagctgatga agaaccgtga aaactgcctt cccgattatc
    52021 tgatgcgtct ggagagcagt cttctgtcag aggaggagaa acagcttctc atcctgatcc
    52081 gaaacgccca ggacgccggt tctcccacag gaagaagctt cctgcgccag tccctctcag
    52141 aacttctggg agcgcctgtc agcgaatacc gccttcgcag gcttttagac gagcttgaag
    52201 aaaaagggct ggcagtcaag cataccggca ggaacggcac ccgcattacg gagcagggaa
    52261 gacgtctgct gcgataatcc agaaaggtca aaactgcaaa cgacgattcc aggaagggag
    52321 ggcggttcca gactctgcca aaaaagcgga cgctggagac ggcctccttt ctgcatttca
    52381 tgtttcgtcc aatttaattg aaatttcatc ctgttttttt ctggtttttg aataattcat
    52441 cccttttacc acaggacagc agatgaacat ggatgtgaaa tttcgtacag gaaaaaatga
    52501 tctgctaatt tgagctgttt tttatatttt atctgttttt tggaattatt ttctttttat
    52561 tggttctgtt ttttcttttt tattccgcta tcctcttaat ttttttgttt tggcacgttc
    52621 tttgctttca tattttccaa aataatattt actaagggag aggctctccc ttacagactg
    52681 gagggatatc atggaaaatc caattattgg agtatttgca gacacaatga gctgtaataa
    52741 aggaggattt ggagacgtaa ccaggcaata tataaacgcc gcctacataa gcgctgtgga
    52801 agatgccgga gcggttccat ttatcatacc tgtcagcaat gatctggaaa agacaaaaaa
    52861 gctgattgat ctgtgcgacg gactgctctt tcccggaggg gaagatatcg atcccggcta
    52921 ttacggtgaa aatcctcata aaaatctggg agaaatccgt ccggaagtag acaaatttct
    52981 ctttcacagc cttctttacg cgctggagca gcgaaagcct gccctgggaa tctgtaaggg
    53041 gatgcagatg atggttgtgg ctacgggagg ctctctctat caggatatct attcccagag
    53101 agaggaagaa accttcctgc actgccagtc agggcggcgc acttatgggg ttcatcaggt
    53161 acagattgac aaagacagcc gtcttttcca gattctcgaa acagggcaga ttgctaccaa
    53221 cagcatgcac catcagagcg tccggactct tggaaaaggc cttcgtctct ctgcacacac
    53281 agaagatgga atcgtggaag cagtggaaag ccttgacgga cggctgattg gcgttcagtg
    53341 gcatcctgag gaaatggttc ctgaaagcgg tgccatgaaa cggctgttta aaaatctggt
    53401 tcagagagca tctgtgtaaa cgaaacaaga gaggaaagag agggcaaatc tcctatgcaa
    53461 gcagaaaaaa agaagaaaga atctatgagc atgtggaaaa tcattctcat tgttaacctg
    53521 gcagtatata ttctgtcatt tatcattccg tccggagcct atcagcggga tggaaaaatg
    53581 gcggttccag gcacctatgc cgtagtcgac aaaacctatt tgaatcctat tgacgtaatt
    53641 ctggcggtgg gagacacggt gtactcctcc tttggccagc tgttcgtcac tctgattatt
    53701 atgggcggca tgatgggtat cgtcaactcc accggcgttc tggaccgggc tctgggaaac
    53761 ttaatccaca ggctcaagga taaggctttg gcaattatcc ctatttatgt atttgcaacc
    53821 gctctattgg ggtgcgtagg atctatgatt tctactgtca ttttatttgt gcctttaggg
    53881 cttctaattg ccaagcagct tcgggcagac cgcaccttcg ccgtcggcct ggtaattctg
    53941 ggttctttta caggttttat gtcttcacct atcaatcctt taaccggagt gatgggacag
    54001 gagatcgcag ggctggttcc atattccgga gcagggctga gaacgattgt caccattctg
    54061 aacgtctctg tggtttctgc ctatctgata tggtgggcaa aacgctgcca gaaaaacaag
    54121 gctgtctatg aaagagattt tggcggagaa aaagccctgg agccggaaga ctatgaacgt
    54181 acctatcagc ctctttccgg acgggaagca gccatcctgg ttgtcttttt tggcgcattt
    54241 attttcttcg cagccggcgg tcctaccctt ggtctcggaa tgactcagct gggttccatt
    54301 atgctgtcag tcgcttttgt ggaaggtatt ctggccggat ataaactgga tgatatcatg
    54361 agcaacttcg tcaaaggaac tcagtccatg tgcggagtta tggtatttat ggtgctggct
    54421 tctattatga gcattatttt aaaccaggcc ggcatacttg attccatcgt ttactacatt
    54481 tccattcctt taagccattt aagcagcgcg atggccgcag tgggcatgtt tattgcaaat
    54541 gcctttatca atgttttcat cggttccggc tctggccaga cggtagtcgc tatgccaatc
    54601 atggctcccc tggccgacgt ggtaggcgta acccgccaga tggctgtcct cacgcttcaa
    54661 tatggcgatg gatttaccaa tctgttcctt ccgactaatg taaatctcat ggcctgcctt
    54721 gccatggccg gagtagactt taagcggtgg attaaatttt tagttccctg ctatgcgatt
    54781 ctgtttgtaa ttatggtcat ttccattttt attggaacag ccattggatt ctaaaagagg
    54841 aggaataaat catgatatcg gataagacat tacaggaaga gctgatacag ctgtcagacg
    54901 agctggaaaa gcagacgatt cagctgcgcc gggaaattca tcagtgtccc gaattatcct
    54961 tccatgaata taagaccagc agggtcgtta tgcgggagct ggagcggatt ggaatccctt
    55021 atgaggaaag tccgcagaag ccaggtatta tcgccaccat cgacagcgga aagcctggaa
    55081 agtttctaat gctgagagca gatatggatg ctcttcccat tcaggaatct acaggacttg
    55141 actttgaatc ccagacaagc ggagtcatgc acgcctgcgg ccacgatgtc cacacagcca
    55201 atctgataac cgttggagaa atcttattcc gcaccaggga acgctggaat ggaaaaataa
    55261 agctggtctt tcagccggca gaagaaaacg gaggaggggg ccgggaaatg atcaaagccg
    55321 gccttatgca ggaaaaaccg gatgcctgct ttgctctcca tgtaaaaaat ggagttccgg
    55381 gacgtatttt cctgaagcag aaataccttt cttcctactc tgacagctat accttaacga
    55441 tcagaggacg cgcggctcat tcctccacac cggaggaagg cgtggacgct atttacattg
    55501 catcagcgtt gatcatggcc ctgcacggaa tttcttctcg caatctctct cctatggccc
    55561 agtccacgct gaatgtgggc actattcagg gcggttctgc tcctaatatc atcgcggatc
    55621 aggccgtttt aggggtaatg ctgagaaatg tatcaaagga atccagacag gccatgaggc
    55681 tccagatcga gactctggca aaaggaatct ccgaatctat gggcggaacc tgtgaaattg
    55741 cctttcgcgc cggttatccg gctgtctaca atgacattga ctttacaaaa tttgtggagc
    55801 agaccttccg cggcaatgca gagtgtctgt attcgaatat aaaagatggg cgtcccgaaa
    55861 attggttgat cacggatctg gatcctatgc tgggagctga agattttgga tttttcgctc
    55921 aggaagcgcc ttcctgcatg atttttgtag gaacaggggg agacgctccc atgcataacc
    55981 ccaatttcca ggtggatgag cagtatatta agctctgtac cagggctatg gccttgacgg
    56041 ccgcagaata tctgtcttct gcccggtaaa atagttcgag aaagcgccgc agtcccatca
    56101 aaaccgatgg gactgcggcg cttcctctct gctgtcaact cttaaagctt atttccgttc
    56161 cgcccgaatt ttctcttttt aaacctgaga aaaggaattt tcgtggctgc ggcctccatc
    56221 cggcactggt tgtccttctg gcacgctcgt atcatctcgt ccagctgcct gaaccgctcg
    56281 tcctctttct cgtcggccac ccgcatcagg taatccatct ccttgagaag cttctcatga
    56341 accatataag cgatatcctg gctcagcttt tcgcagtttt cttccatagc acgcccaatt
    56401 acatgattca ggagtctctg cacctgttcc agctgcccgc tctctaccag ctcctccact
    56461 gaaccgccct gtttcgtctc ctcagcgcag gaaacagccg taccgggaac cgtctgagcc
    56521 tccgaagcct ccccgctccc gcctcctgca ggatccgcgt ccttcagagc cgccagcacg
    56581 tcctcctcca gcacctcgtt ggggataatc accttcccgt ctgattccag agacttggca
    56641 agcgcagttt taatcgcttt cagctgatac cccttatcct tcagcatctt tacctgcctg
    56701 aacagacgaa tgtgaaactc tgtataataa cgatgcccca tctcgtttct gggtatccca
    56761 agctccagct cctcctccca atatctcaga acgtgcgcct ccacatccac cttcttggaa
    56821 gcgtctgata tcagataatg tacctcagcc ataattcaat cctctccttt ggttcacaat
    56881 atttcgtagc ctgttaatac tatatgcgaa ccccagcgca attatgtcaa aaaaagaagc
    56941 tgggctgaga cagcttctga aggcgataaa aaagagaaac ggggaaagtt tcctggttcc
    57001 aattcaaagt tacccaaagc tttccctgct tccctttttc tggcggaaag aaccgctcct
    57061 atctgtgtat ttttctccct acttggccag attctcaaat ttcgtaagct ccggcctcca
    57121 gagcaggttg acggttccga tggggccgtt tcgctgcttg gcaataataa cctcggcgat
    57181 gttgggattc tccgtatcct tgtgatagta atcgtctctg tagaggaaca tgaccatatc
    57241 ggcatcctgc tcgatggctc ccgactccct cagatccgac agcataggcc ggtgatccgg
    57301 cctggtctca caggcgcggg acagctgtga cagggcgata accggcgcgt tcagctccct
    57361 ggccagggcc tttaaggaac gggaaatctc ggaaatctcc tgctgcctgt tctctccgcc
    57421 ctttccgctt ccgctcatca gctggagata gtcgataatg acaatgctga gcccatattc
    57481 cagcttcacc ttcctgcact tggaacgcag ctccataatg gagatacccg gcgtgtcgtc
    57541 gataatcagc ttggaatttc caatggttcc aattccctcc accacagcgt cccaatcaga
    57601 atctgacaga gttcctgtcc tcagcttctg ggaatccact ctggactcca tggaaagcat
    57661 acggttgacc agctgttcct tggacatctc caggctgaac accatgcagg gcatattttt
    57721 ccttactgca atgtgatcca ccacattcag cacaaaggca gtctttccca tggacggacg
    57781 ggccgcaatc agcacaaaat ccgagggctg aaagcccgag gtgcgaaaat ccagatcgtg
    57841 gaagccgctg ggaattcccg tcacgtttcc ctgattctta gacgccgtct caatcttatc
    57901 cagcacgttt aacgccacct ggcggatagg cacgaaatcg ccgcttccct tgctctgaag
    57961 caggtcgaac acagacttct ccgtatgagc cagaatatcg tccagcttgt ccttccccgc
    58021 atagcaggtg ttggcaatct cctcgttaat cttaatcagt cttctaagca ctgccttctc
    58081 acgcacaata cctgcgtagg acttcacgtt ggcggaggtg ggcacagttg tcataatatc
    58141 ccggacaaac tccaaactgc tgacctccgg gggaacgtcc ttctccttca ggcggttctg
    58201 gagcgtcacc agatccaccg gctttccctc gttaaacaac tccaccatcg cctcgaacat
    58261 cacgccgtac tggtgctggt aaaaatcggc gcctgtgaca atctcagacg ccgaaataat
    58321 agcttcgcgg tccatcagca ttgcgccgat gacggactgc tccgcctcca cactgtgagg
    58381 aagcacgcgc ttaatcagcg cttcatccat gcttatgcct ccgttacctt gacacgaaga
    58441 gttcccgtta catccttgtg aagcttaacc ggcacttcgt gggttccgaa ggttttaagg
    58501 ggctccggaa gcaccagctt cttcttgtca atgtctatct tcagctgctc ggacacagcc
    58561 ttggcaatct ccttgccgga tacggatccg aacgctcttc cgccctctcc ggcgcggatg
    58621 gataaggcaa tggacttatc ctctaaaaac ttggccagat ccttggccgc tgccaggtgc
    58681 tccgccgcaa tcttctgctc gtttgccttc tgaagcttta aatcgttcaa gttctgagcc
    58741 gtagcctcca cgcccagatt tttctttaaa ataaagtttc tggcgtatcc gtcgtttacc
    58801 tttacaatct gtcccttctt tcccagggat tttacatcct ccaataatac aacttccatt
    58861 ttatatttct cctttctcga tcatctgcct gagcatggcc ttcagttttt ctctggcctc
    58921 ctccatggta gcgtccttta actgggctcc ggcaatggtt ctgtggccgc cgccgcccag
    58981 cttctccatc atcacctgca cgttcacctc gtcaatagaa cgggcgctga agaagatggt
    59041 atcctttacc tgcgtcatga caaaggacgc cttgattcca atgatattaa gcagctcgtt
    59101 ggccgcctgg gcgcctatga cagtcgggct ctccagtccc tcggacggac actcggaaat
    59161 ggcaaattcc ttctcgaaaa tctccgctct tctgactgcc tccgccctgg cccggtagtc
    59221 ctccacccgg tcgcggaaca gctttctgac ccgcaccaca tcggctccgt ttctcctcag
    59281 gaaggccgca gcctcaaagg tccgcactcc cgcctgattc atgaaattat tcgtgtcaat
    59341 gacaattccc gcatacatgg cgtccgcctc cacagagcgc atcttaatgc cgtctcctac
    59401 gtactggaga atctcagaaa ccatctcgca ggtggaggaa gcgtagggct ccacatagga
    59461 gagcaccgcg ttctcaataa tctcgctgct ctgtctgtgg tggtctaata ccataatggt
    59521 cttaaccatc tttaacagct ccggcgcctc cgtaatgctg ggccggttca catccaccac
    59581 caccagcatg gtattggcgt ctgcccgggc tgccgcctcg tctcctgtca ggaacaggtc
    59641 ctccggatag tccgggttat tctgaaaccg ctccatcata gggcgcacgg aagaattgac
    59701 gctgttaatg acaatgtgtg cctttttgtt aaacgccgcc gcaatcctgt agattccaat
    59761 ggtggctcca aaggaatccg gatccccgat ccggtgtccc ataatgagca gcttatcctt
    59821 cgtctccatc agctctctca tggcgtgggc ctttaccctg gcctttaccc tggtggtctt
    59881 ctccagctgc tgggacttgc cgccgtagta ggtgatcttg gctccgtcct tcaccaccgc
    59941 ctggtcgccg ccgcggccca gagccatgtc aatggctgtt ctggcgtact cgtagtttct
    60001 gatataggtc tctccgttca tacccatacc gatactcagc gtcacagcca tctcgttgcc
    60061 gatgttgacc gttttaacct cctccagaag ggcgaaccgc tccttctcaa gctccttcgt
    60121 atacttctgc ttaatggcaa agaaatattt gtctttttcc agtttcttca caataccgtc
    60181 taaattagaa atatacttgt tgatctttcg gtcaatgaga gccaccagaa gcgagcggcg
    60241 cacctcctcc acgctctcca gggcctcgtc gtaattgtcc agataaatca gtccggccac
    60301 caggttctga tctgcaatct cctgctttaa agccagaagc tccgtctcgt caaacagata
    60361 aactgcccac agcgtctcat cctcgtctcc gtccggcgcg tccaggttca gttccccgtt
    60421 ctcgcctgcg cagatgtggc ggagctccat ccggtaaaag ctgtctccat aggtaatgtg
    60481 aagacttccc tccccgtcga ttccatttaa aatctccctg gtcagctccg gaaacagccc
    60541 gaacagcgtc ttattcttcc ggtcatccct cacaatatcg gcaaacccgt cgttcatcca
    60601 cagcagaaga ccgctttcat ctgcaatcgc ataggggaaa gccatatccg ccgcaatatg
    60661 ctcctgaagc tcggcatact gagcagaaaa ttccagaagc ccccctagaa gccgcttcct
    60721 cttatacaga taaagccatc cgcataccgc cgcataaaac agtgtaaaac cagtcatgac
    60781 aatgccggcc tttaaatcca tcagacccac caccacattg gcggccatca gaatcactgc
    60841 cataaaaagc ggccactgca gatatgcccg aagctgcccc tgtattctga tatcctcttt
    60901 catctctctc tcctgtttca ttttcgagaa cgctccccgg aaatcccgca gagcgtttat
    60961 ccttttgtat atctatagat acaaattata gcataaaggg ggcggttcgt ctaggcacgc
    61021 aggacaaacg caaaacaatt tgacatcccc ttcttctgat ggtatacttt ccctaaacca
    61081 agggagctcg taggcgggct gagaggaagt aaccaaactt cgacctttat cacctgattt
    61141 gggtaatgcc aacgtaggga ctatacagac gcggccatca taaagccgtc agccgcattc
    61201 tcagatctgg atccgcatgg tttcagatct ttttttccgc ctccgttctc ctctcattat
    61261 gaaaggagca tatttatgaa ccagacagca catccggccc caggcccctc ttcccgaacc
    61321 tactccacac agatggacgc cgccagaaaa ggcattctca caaaagaaat ggaagccgta
    61381 gccagacagg agcgctttga taccaagcgt ctcatgggcc ttgtagcgga gggaaaaatt
    61441 gccattcccg ccaaccgcct ccacacctgc cttcatccta acggcatcgg ctctatgctg
    61501 agaacgaaaa tcaacgtcaa tctgggaaca tcccgagact gcgtggatct ggatatggaa
    61561 cttcagaagg tcagcgacgc cgtggccatg ggcgcggaat ccatcatgga tttaagctcc
    61621 ttcggagaca cccggaaatt ccgcagaaag ctgacggccg agtgtcctgc catcatcggc
    61681 acagttccca tctacgacgc ggtagtctat taccacaagc cccttgggca aatcaccgct
    61741 gacgagtgga ttgacattgt ccggatgcac gccatggacg gcgtcgactt cctcaccatc
    61801 cacgtaggca tcaataaaaa tacggccagc cggttcaagc aggcgaaacg cctcaccaat
    61861 attgtctcca gaggaggttc cattattttc gcctggatgg aaatgacagg agaggaaaat
    61921 ccattttacg cgcggtttga cgaaattctc gatatctgcc gggaatacga tgtgacttta
    61981 agtcttggag acgcctgccg tcccggctgc ctggaagacg cctcggacat ttcccagata
    62041 gaagagcttg tcacgctggc ggagctgacc agacgcgcct gggagaaaga cgtgcaggtt
    62101 ataattgagg ggccaggcca catgccttta gaccagattg cagccaatat gaaaatccag
    62161 cagacgctct gcaagggcgc tcccttctat gtattagggc ctcttgtcac agatgtggcc
    62221 cccggatacg atcacattac tgcggccatc ggaggagcag tcgccgcagc cgccggcgct
    62281 tccttcctct gctatgtcac tccggccgag catttacggc tgccggatcg ggacgacgta
    62341 aaagagggaa ttatcgcgtc gcgaatcgca gcccacgccg ccgacattgc gaaaggaatt
    62401 cccggcgcct cagactggga tcgaagcatg agcgaggccc gcaaaaagct ggactgggaa
    62461 gaaatgttcc gcctctctat agatccggag aaagccagac gctaccgcgc ttcctccaaa
    62521 ccggaaaaag aagatacctg ctccatgtgc ggaaatttct gcgctgtcaa aaatatgaac
    62581 cggatcctgg acggagaaat tgtctctatt tttgatgaat aaagatccaa aagagggcgc
    62641 ggccaaaatg ccgcgccctc tctgcatgtc aaatcctgtc tgttatgcgc tttcctgcgc
    62701 tgaactggtt tctgatatcc tgccgtttct gctgctttat tctgctgctt ttatttttct
    62761 ttattttgct gctctgtttt cctactttac cgcatcgcag agtatctgta cgcaggtctc
    62821 aattcccagc tggccgctgt ttaacataat atcgtagttc tcccggcggc cccacttctg
    62881 gttggtgaag gtctcgtaat gaatccggcg ctttttatcc gtttgatgca tgaactcgtc
    62941 gatatagtcc tcgatctcgc cgtactcagc caaagctctc tgtctgcgta tctctttatc
    63001 acagtaaata aataccttca gaacgtcgtc cctgtccttc aaaatgtaat ccgcgcagcg
    63061 tcccacaaac acgcagctgc ttcttctggc cgcatcctga ataattttct tctgggcaat
    63121 aaaaatctgt tccgtaagag gcagctcctc aggcttgggc gtcctgggat aggcgatgcc
    63181 gtataagctt cccatagcga aattgtagag cagactgttc gtcaccctct gttccttatc
    63241 tgcgatcagc tccggtgaaa aaccgatctc cttagccgcc aggtcaatca attccttatc
    63301 atagaagtcc atcccaagct tctttgagac cagctggcca atctgacgtc ctccgcttcc
    63361 atattcacgg ctgattgtaa taatcttttt actcatagta caggcctcct ctcgcggcta
    63421 tttctacctg tattttacca tatcagccgt taattttcaa ttaattaatt tactaattct
    63481 atattttgcg acactttaac gtatcgccgc aattccgcag ccgtctctgc tttccttcta
    63541 tgcgtccggg atgccgtcct ttttcggcat ttttctcgtg atgataaaat agcagatcag
    63601 atgagcgctg gctgtgatga tccagctcac cgggtaggaa acgtacaggg aggtcagggt
    63661 tctctgctgg gagaaaatcg tgaagatcca cagaattctg agaccgcagg ctcctgtcag
    63721 agagacaatc atcggaagca ccgaatagcc gattcccctg aggcttccca ccatggtatc
    63781 catccatccg caggtgaaat aagtggtggc gattatgctc atacgaagca ttccaaaccg
    63841 gattacctcc ggatccgtcg aatagatccg aagcagatcc tctccaaacg cgtaagcgcc
    63901 aaatcctaac agcattccca ccgcggtcac cgtccccagg caggtaaaca tgatttttgt
    63961 aattctggta tatttctttc cgcccatatt ctggctggta aagcttaaat tcgtctggta
    64021 cacagcgttc atggcgttgt atacgaagcc ctctatgttg gcggaggccg cgtttccggc
    64081 catggccacg gatccgaagg agttgaccga cgactgaatc aggacgttgg aaatagagaa
    64141 gattgcgccc tgcattcctg ccgggaggcc gattttaaag atctggaaca ttttattttt
    64201 atgaatcttc agctttttca gctccagctt caggcctccc tcgctctttc ctaaggcgcg
    64261 cagcaccagg aaggcagaaa tggcctggga aatcacagtg gccagggcga ctcccgccac
    64321 gtccatgtgg agacaaatca cgaaaaacag atttaaggct acgtttacca cgcccgccgc
    64381 gctcagatag tagaggggac gtctggtgtc ccccaccgcc cgcagaatgg cgcttccgaa
    64441 gttataaagc atcaccaccg gcattcccgc aaaataaatc ctcatataga gggccgcctt
    64501 gtccagcacg tcgtccggcg tacccatcat ttccagcaga atcctggaaa aggccagtcc
    64561 catcacgatc agaaggactc cgctgaccag gctgagggca atggcggtgt gcaccgactc
    64621 gctcacatcg cggtctctct ttccgccgta ggctctggcc accaccacgt tggcgcccac
    64681 agaaagaccg ataaaaatat tgatcaaaag attaatcaga gacgtcgttg aaccgacagc
    64741 cgccagagac ggacttcctg caaaccgccc taccacaatg acatccgctg cgttaaataa
    64801 aagctgcagc acgccggaca gcatcagcgg aatagaaaaa atcaggattt tctttagtat
    64861 atgcccgctg cacatgtcca tttcgtagct ttttttcatg gttttactcc ctccccctgt
    64921 taatatttat ccatgttcag tatataaata ttatacgcaa aagcaggaag ggattcaatg
    64981 aaattctact caaactgctt cccaaatcca aaggccccct gtaccagaca ggtcttcgcg
    65041 gcaaactccg cccccgcggg aagcgccctg tctgccgtct ctcccttcag cacagacagg
    65101 agaaaagccg cagcgaagga atctccggct cccagcgtat ccaccgcctt tacaagcttc
    65161 ggcggctgaa ctaaaaactg ctccccgtca taataaacgg ctccatggct tcccctggta
    65221 gctatgattt ttctgcatcc cgcttttttc atcctccggc agacatccct ggcctcctcc
    65281 tccgagacag agccacagga aaggaacaca taatccgcat aaggcgccgc agcggcaacc
    65341 ttctcttcct ccttccactg tccggaaaaa tcataggaaa gagagactcc tgtcgacttc
    65401 accagagcca gctggctgtc gaaatgactg ttattgctgg tgtggacatg ggaaaagcct
    65461 gaaatgtact ttaaatcctc ctcgtccagc tgcagcggac gttccttcgc aatcccgccc
    65521 ttgttgcttc ccagaaagat gcggtctcca tcctcaagag tcactctggc gcatccattt
    65581 tctccctcat actggcggca cctcccgtgt tcaatgccca attcatccag cgtccgaatc
    65641 acatgggccg cctcctgatc cgttccaaat acccccatgt aggatgcgtc tgcccccagc
    65701 tgctttgcat acacagaaaa attcaaagcc tgcccgcctg gaaacatagt cttcaagtga
    65761 atatatttgt cgcatacatt gtccccaata ccgattacct tcatcccact gtctccttcc
    65821 ctgtttcgcc aaaaatagat tatataatat tatataatgt ttatagattt atcttaatca
    65881 acttctccct ctttgtcaac ttattttcaa tctaaaaaag gagacctgct ctccctcctt
    65941 cgctgtgcga aagccttgga gcacatctcc ttctctctgt tgatttattc tccgtccgat
    66001 tcatagaccc gcagcgcaaa ccggtctccg ttaatcacct gaacgcccgc gtaaaccggc
    66061 tccccgtccc ggtcgtaggc cgtgcttctg acaaataaaa ggtaatctcc ctttttcaca
    66121 gccaaaagag ccgcctcctc tggcgtagcg cggcacagct cgatgatctt ttccgaaccg
    66181 gtcaccttca ggcctgtttt ttcccgaaga tagtcaaaca gcgaattatc gtcaaattta
    66241 gcctccagca aaaacgcgta cttgagagga aaatagctct tctctatctg tactggttcc
    66301 tgatccgcat agcgcagacg gctgatatag attacgctgc ttccagcctc cactccaaga
    66361 ctctctgctg tttttctgtc agcaggaatc aggcggtttt ccagcatcct ggctcccggc
    66421 ttcactccca tctgagtaca catttctgta aagctttgaa gcttcttcat atttcgaaac
    66481 agctttgggc ggaccacaaa ggttcccttt ccctgctttc gcaccacaag ccctttctca
    66541 gtcagagaac caatcgcttt ccggacagta atcagactga ctccatattt tttcgccatc
    66601 tctgcctctg tcatcagtct gtcacctggc ttgtattcac cgctccttat actcttttcc
    66661 acttcttcca taagctgaac ataaagaggc gtcatcgcgt cctggtttaa cattcaccat
    66721 ccccctcaaa cgatttgatt ttcctgcatt ttcccagcat tccagcatct agtaatttca
    66781 ttttataata gaaaaactga aatggcaaga ctcaaaaaac cccgcaccat aacggtacgg
    66841 ggctttcacc ttactgattc cgaatcttac tcgcatgtat aaggcatcag agcgatgtga
    66901 cgtgctctct tgatagctac tgtaagagct ctctggtgct ttgcacagtt tcctgtgatt
    66961 cttctaggaa gaattttacc tctctcagat acgtatctct ttaacttgtt tgtatccttg
    67021 taatcgattg ttccgttctt ctctccacag aaaacgcaaa ctttttttct tctgcgcata
    67081 ccgcctcttc ttaccttgga agcgtctgcc ttatcacctt tattgaatgc cattggtgtt
    67141 ccctccttca aaactgccga tgctgcaatc cttcgttcaa ctggcgccct ggcgggcctt
    67201 cacgtctcta gttgaacgga agtccttcat cttctactcc gtcggggata ttcataaagc
    67261 cgtcgccgat tgcgcttgca ggcgccggac gctgcgctgc ctggtagccg ccgtcatgtc
    67321 ctgctccctg ggaagcgttc ttgctctcag cgaactcctg atcctcaacg attacatctg
    67381 ttgtataaac tttctgaccg tctctgtttg tgtagctgcc tgtctggatt cttcccgtca
    67441 cgagaacctt ggttccctgg tggaaatact tctctgcaaa ctctcctgcc ctgtcaaatg
    67501 caacgcactg gatgaagtct gctgtctgcg ctccgtcatc ctggcttctg cggcctcttc
    67561 tgtcaactgc caacgtatat ctggcgattg ccatagcccg ctctccctga gaataccgaa
    67621 cctccggatc tctggtaagt ctacccatca gaattacttt attcatacga tcactctttc
    67681 tttatttatg catcctgtct tacgcataag tatctgatta ccggctccat gatacgtaca
    67741 tgtgcctcta cctcgttcgg gcatgtggaa tcagactcaa actggataaa gtagtagaag
    67801 ccctctttca tcttctggat ctcgtaagct aatctcttct taccccactc gtccacattt
    67861 gttacagtac cgccgaaacg tgtgatgtaa ccttttactt tctcgatggc tgctgctctc
    67921 tcttcgtctt ccagcttcac gctaagaaca actgctaact catacttgtt catgctgcta
    67981 aacctccttg tggtctctga ctccctgact tttaacagag agtaaggaat ttcaataata
    68041 tatcacgaat atttatctta ccagagaaac ctgattaaat caagctcttt tttgcttttt
    68101 ctccgtgttt ttctttctgt tacgccttct tttccccgtc tgccgagcgg agtcctcttg
    68161 tgctcttctc caccagcggg cgggccatca tcacctggtg gccgcagccg gtacatttca
    68221 gcctgaaatc agcgcctacc cggagaattt cccactctct gctgccgcag gggtggggct
    68281 ttttcaattt tacaatgtct cccacttcat atgtcatgtc tgtgtctccc tgttttcaac
    68341 tgataaaacg tctcttatct gattatctac agtccggctg cctccgctaa cgcctctccc
    68401 acgctgccgc agatgaccag atctgcctgg ctgtctctgg aagtggccga cttattgatt
    68461 aataccagtt tcgttcccct gtaatagtca atcagcccgg ctgccggata gacggtcaga
    68521 gaggttccgc cgataatcag cacgtcggcg ttcctgatat gttcaatcga gcgggagagc
    68581 acactgtcgt ccagcccttc ctcgtaaagc accacatccg gcttaatcac tccgccgcag
    68641 ctgcatttag gaactccttc gcaggagagg atgtgctcca tggaataaaa ccgaccgcat
    68701 ctttcgcagt aattgcggtg tacggatccg tgaagctcca gcacctcccg gctccctgcg
    68761 gcctggtgga gaccgtcgat gttctgggta atgacagctc tcacctttcc ctcctgctcc
    68821 agcctggcca gtgccaggtg ggcgcggttg ggcttcacct ccggaaacag cattttattt
    68881 ctgtagaaac ggtaaaattc ctctgtcttc cttaaataaa aggtatggct caaaattgtc
    68941 tccggcggat aatcatactc ctgattgtaa aggccgtcca cgcttctgaa atcgggaatt
    69001 ccgctctctg tggagactcc cgctcctccg aaaaatacca cgttccggct ttcctgaatc
    69061 cacttcttta aaagctctct ctttttcttt tcctcagcgc agttttctcc catcatccgt
    69121 tctcctctcc ctcatttaca cgacctcgtc taaaaatacg ccgtctatcg gacgcacgtc
    69181 ttttgtccaa gccggaagag cggttccgtc cagtcttctc tccccggcca caatctcgct
    69241 taaaggcctg aagccgaaca accactgggc cagaccgtca atcgaaatcg ccagagtctc
    69301 cttgctctgc ttctcccccg cctcgtctgt ctttaccgcc ctggcccctc cggccttgtc
    69361 tgtaacaatc gcatatcgtc cggcgcaggc gggaagaaat ggatctgcaa tctccagata
    69421 tccgtccggc tctgattccg tttttttcgt ggtcccgtct gactgctctg cgcccgcagc
    69481 ggcagaatct cctccggaaa ccatctggaa aaaggcctcc acatccgtca ctctggccat
    69541 aattgcaggc ttttccttct ctttttcccg ggtaaccaga cggtcctctg cgtagagaag
    69601 acgctgttct ctcttctcaa gcccccactc gccatggagg cctgccagct tctcctctcc
    69661 gttttcctct ttcattaaaa actccagaat gccgtcctcg ctggccaatt cccgcatcag
    69721 acgggctgca taggcctcat ccctgcggca ccaggcctca aaccgctcct tcagccattg
    69781 ttccataaaa gacgccgcca gaaccgcgtc ctcccggctg ctgcatggcc tgcagcttaa
    69841 agtctccagg gccttttctg tcagctgaaa cctgggctgg cggtagataa aagcgaactg
    69901 gaacggccgg taaatagcct cgtctgccgg catcaggaag gtaaacggca cgtgggcccg
    69961 gttcatgtcc tccagcattt ttttgagaat ggagcgcata tggccccggt ggcggctgtc
    70021 ttcggcggta gctaccccta caatataatc gacgggccat tctctgcccc ggcagacaaa
    70081 ggagtaggga ttcagctggg ccatggatac cagttttccg ccttccgcct tgactaaaat
    70141 cctgttgtcc ttcacctttt ccccatagta ataatcggca aaggcgacag aatcatcggg
    70201 aaacgcctcg tgccacagct cccggcagcg ctgcttttcc tcctcgtctg catagcggag
    70261 tccatcctgc cacacggctt ttgcgcttcc gtctgcagat attcctccca gctgcgccgc
    70321 tgtcagctct tcctccgtat cggccagagc ccctattttt tctgcccagt caaagccatt
    70381 ctcctggccg gttccctggc cgaaggaaat ctgctgcacc aggtatttct tagcaaaatc
    70441 aatggggcag taggacattt tcgcctttct gaggccttcc aggcccagat cgtcctcccg
    70501 gttaaccagc tcgattccag gaaattcctc taaaaggaac tgctggttga tcagctgata
    70561 cagtccccgc atctccggat tggccttctc aatgtggatg acagccatcc gctccagcgg
    70621 attatagctt ccgatagaga acgcttccag ctccccgtcc acgtagatac cgcccatgcg
    70681 gatatttaag gaacagcagt ttctgaggat ttcgtgaatg cccctgacct caaaatccag
    70741 gtgctcctcc acgtcctctc cctttttctc tctccagcgg tccaaaaact tccagacgtc
    70801 ctgaatgtag tcgcaggtca gcgtcctgta ttcatatcgt ccctcataat ttctcttaaa
    70861 agcgttcaaa tggtttttct ttttgtgaag cttctttccg gaaagagttt tcagagcctc
    70921 ggcggaataa atataatctg cggccccctc ctcttccttt accagataat actccggagg
    70981 cagattcagg cacttcacag cctcctcatc cgccaggttg attaccagag gataccccag
    71041 ctcttcatta aaatactgtt ctaatgcatg aaacgcttcc ttcagatcct cttcacggca
    71101 caggggcatg gcagaaaaca cccgtccctt atattccatc agccagagaa gggctctgtc
    71161 ctcccatatg gcataccgta cattataata ctctctccag agaaagctct ccagaaatac
    71221 gctgtcacag gttttattgc ggcgcatcaa acggtcaata cgataatcga tcatagattc
    71281 ggcaattccc ttattcagca acagaatcgg gggaaacatc caaagttccg aatcccaga
//
LOCUS       DBMDUW010000006        70225 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_436_length_70225_cov_3.650448, whole genome shotgun sequence.
ACCESSION   DBMDUW010000006 DBMDUW010000000
VERSION     DBMDUW010000006.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 70225)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 70225)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70225
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_436_length_70225_cov_3.650448"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..411
                     /locus_tag="ACZPCR_02255"
     CDS             <1..411
                     /locus_tag="ACZPCR_02255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007862971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HIR1229745.1"
                     /translation="DLMLVLETHGEHGTGKAVKEIADLVGSERVRVAYDTANVIFYGG
                     VNPAEEIEDCMDAVSYIHLKDKDGEDKEWNFPAPGKGKVDFPRLFQTLEKARNNSPFS
                     IEIEFTPDGAGSLEAVNQAVQDAADYLKGQGFKL"
     gene            473..1552
                     /locus_tag="ACZPCR_02260"
     CDS             473..1552
                     /locus_tag="ACZPCR_02260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009663276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HIR1229746.1"
                     /translation="MRKKMRMTALMMTAFMAASLTACGSKETAETEAKESSAAEKTEA
                     ASKAEGEAEKPAEDLTFGYIAYDMTDIWNEYSANSFEYAAKEAGVEAVVLDSKNSLEE
                     SITAMESLIQQEVDGISIFPISTEQGAQLVKMANEAGIPVTVENFAMDIEDPGDYIAS
                     VACEYDKIGYEAIKYIAEQKPGAKVFFCAGQEGAGVYEKYQEGVDKAVEELGDKIEIV
                     ATLHGDWLTDKAYNVTTDFISTGEEFDYIFANNGMMAQGCYQALKDAGMENIPIVSTG
                     GSPDDYQMLQDGIESANMTAPVSVQGVQTFKNLYDSVAEGKTPEKFVSLPILPIGQDN
                     LDDYIAWDDYEKAYEFVYSGEENAE"
     gene            1586..3124
                     /locus_tag="ACZPCR_02265"
     CDS             1586..3124
                     /locus_tag="ACZPCR_02265"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009220404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HIR1229747.1"
                     /translation="MKADYAEKPVLKMTGIEKEFSGVYALSGITFDLYKGEIHCLVGE
                     NGAGKSTLMKVLSGAYSPSKGTISIDGREYSSLTPALSRELGINIVYQENDLVPSMSV
                     AENIYVGNEVSDRFGFIKYKELYQKTKEQMEEFSIHLDPSAKIEDLSVSDQQFVKILK
                     ALSAQTRVLIMDEPTSMFNVEDAAKVLRLAEAIAARGISIVYISHSLEEIRRIADRIT
                     VIRDGAVVRTYENENRDISLALITQDMVGRPVDTFFKKDKNPIGDVCLEVKGLKLSKE
                     SPEISFSVRHGEILGIAGMVGAGRTEIVRAITGADPKYAGEILIDGTSVEIRNPEDGI
                     KAGFAHITEDRQGLGLMLHNSVLENGTIIGLREKIKGFFVNIKKHPPLIEPIFKELRL
                     KTPSVWTEAVYLSGGNQQKVVLAKWLYVQQEIYIFDEPTRGIDVNAKAEFYKQMSALT
                     KQGKCIIMISSDMPELISMSDRILVVKKGQIEGELVGEQITEQEIIRRALGVNRNDAE
                     ETTY"
     gene            3099..4043
                     /locus_tag="ACZPCR_02270"
     CDS             3099..4043
                     /locus_tag="ACZPCR_02270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009220405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1229748.1"
                     /translation="MTPKKRLIKEQRVLLAIVIVVIVAAVSAINPRFIQMKNLITIFQ
                     QISVTGILTMAMSMLLIGGGIDLSIGNIMVLSGVVMASVIHSTGNTALAVAAGMAAGT
                     LCGALNGVIIAKSKCIPLIITLGTSEMFYGMALTISGGRIMSFGGAFNAIGKTKLFQI
                     FPVMLLVLAAMVVLSYILMNRTKFGRRIVAIGGNEKNAFLSGINIVRYKVILYGIAGL
                     FCSVAAIIFSARIDSITANAGAGYETSALTAAIIGGVTFDGGKGTISGAFLGCVLMGV
                     ISNAMNILQVETYIQTIITGAIIVCAVVLSNINNIRRR"
     gene            4093..5118
                     /locus_tag="ACZPCR_02275"
     CDS             4093..5118
                     /locus_tag="ACZPCR_02275"
                     /inference="COORDINATES: protein motif:HMM:NF014893.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="HIR1229749.1"
                     /translation="MVKIAVIGAGFMGRTHAEAYSRIELAQVAAVCDRDKALGEKFAE
                     DFGCSFYEDFDTMAAECEFEVADICLPTFLHETFTVRAAEHGKHIFCEKPATLSVESL
                     DRMIGAAEKAGVNLMIGQVVRFWPEYRTAKQMRDNGELGELNYAYGARLSEHPAWSEW
                     YRRPENSGGGLFDLHLHDIDFFCWMFGEVESVFASGKKNELGCWNFVNSTLNFQSGQS
                     ASVQGVIEMTKGYPFTMELRLTGSKATYEYIMKAGANLEDVASARRDTRVYGQDGARI
                     LPLDETDAYETELRHFVACISEHRESEIIPAASARKVMCVMEALKTSLETGKQVAVDY
                     GKRQPLV"
     gene            5135..5983
                     /locus_tag="ACZPCR_02280"
     CDS             5135..5983
                     /locus_tag="ACZPCR_02280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009663253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HIR1229750.1"
                     /translation="MKTGVSMFSFTEDADLKHLFPLIKKAGYDGVEPVFSEYGYLNEK
                     TSKEDIREIGKIAREEGLEIPSVGVWSLWKYNLVSNQEETRRRAVDIVKKQVEAAALL
                     GADTVLVVPGYVGCDFVEEPERIRYDKAYERCLEALKELAAFGADHNVCIGIENVWNR
                     FLLSPLEMKRLLDEVNSPFVGAYFDVGNVIYTGYPEDWIEILDSHIKKIHLSDFRYGA
                     AGMSGFVDLFAGDVDFVKVGESLKRIGYDGWLTLEMLPNYKQFPEVSLLSNRPAVERI
                     AALAQK"
     gene            complement(6095..6358)
                     /gene="rpsT"
                     /locus_tag="ACZPCR_02285"
     CDS             complement(6095..6358)
                     /gene="rpsT"
                     /locus_tag="ACZPCR_02285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008722714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HIR1229751.1"
                     /translation="MANIKSAKKRILVAETRAARNKAIRSKVKTVVKKVEAAIAAGDK
                     AAAQAALLVATSEIDKACSKGVFHKNTASRKVSRLSKAVSSMA"
     gene            6643..7620
                     /gene="gpr"
                     /locus_tag="ACZPCR_02290"
     CDS             6643..7620
                     /gene="gpr"
                     /locus_tag="ACZPCR_02290"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006777345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004175 - endopeptidase activity [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HIR1229752.1"
                     /translation="MAQNDFNPRTDLAVEEREQFTEGEEISGVAVDEWEGEGRLRLTR
                     VEIKNEQGARAMGKPAGVYVTIESEALAENDPSYHEEAAAELGRQLREMIHRCCPGKE
                     RPAVFVAGLGNMQVTPDSLGPRVIENMQMTRHLNLEYRKDFCRTHDLPVLSGIAPGVM
                     GQTGMETAEIVKGAAEETKPDLIIAVDALAARSARRLASTIQLADTGIHPGSGVGNHR
                     RGLTREGLGIPVIAVGIPTVIGAAAIVHDTVKAMIQALLREKQTEDYGAYMEKISSEE
                     QYQLIRELLEPEFGPMFVTPQDIDERVRRLSFTVSEGIHQALYKEGTNR"
     gene            7731..9110
                     /locus_tag="ACZPCR_02295"
     CDS             7731..9110
                     /locus_tag="ACZPCR_02295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HIR1229753.1"
                     /translation="MAGNWKRRRGIGGEKKKLLAGGLSVIVLVLAVFGAGKTGLPSAA
                     AAQEERTVSGANAYAALSSCAALWFPTWIESVDGGEREAKQDGADGLTRFLADRLMEG
                     MFWYRAAERGEDVGRTKPDPAYAHYKKKQEQAKEYSRLADALSASQVLSDSDKGSVLE
                     PERQGAASAGSSDLSAVSPSPAIGTMAGRNLLERAGRPVTGKTYLAEQLADYDYVMKH
                     FYTVHPTAAAGRDMIQAETFLDRDFSLKQETDSEKPQILIYHSHSQEEFADYHTGNRE
                     ATIVGAGEYLAQLLEEKGYQVIHDTSVYDLRDGKLDRNKAYSYALEGVEKILKENPSI
                     EVVLDLHRDGVDSKTRLVQEVNGKPTAQIMFFNGTSQTPDGPISYLENPNREDNLAFS
                     FQMKLCADAFYPGYARNIYLKGLRYNLHLRPRSALVEAGAQTNTYEEVKNAMEPLAEL
                     LDTVLGDGG"
     gene            9309..11123
                     /gene="lepA"
                     /locus_tag="ACZPCR_02300"
     CDS             9309..11123
                     /gene="lepA"
                     /locus_tag="ACZPCR_02300"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004606994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HIR1229754.1"
                     /translation="MAIVDQSKVRNFCIIAHIDHGKSTLADRIIEQTGLLTSREMQAQ
                     VLDNMDLERERGITIKSQAVRTVYRAKDGEEYIFNLIDTPGHVDFNYEVSRSLAACDG
                     AILVVDAAQGIEAQTLANVYLALDHDLDVFPVINKVDLPSADPDRVAAEIEDVIGLEA
                     HDAPRISAKTGLNIDQVLEQIVEKIPAPAGDPEAPLQALIFDSLYDSYRGVIVFCRIK
                     NGTVKKGTPIKMMATGATAEVVEVGYFGAGQFIACDELSAGMVGYITASIKNVRDTRV
                     GDTITNRENPCSSPLPGYKKVTPMVYCGMYPADSSKYPDLRDALEKLQLNDAALFFEP
                     ETSLALGFGFRCGFLGLLHLDIIEERLEREYNLDLVTTAPGVIYRVYKTNGEMIELTN
                     PSNLPDPSEIEYMEEPIVTAEIMVTSDYVGAIMQLCQERRGNYLGMEYIEGTRALLKY
                     ELPLNEIIYDFFDALKSRSRGYASFDYELKGYEQSELVKLDILVNREEVDALSFIVFA
                     GSAYERGRKMCEKLKEEIPRHLFEIPIQAAIGGKVIARETVKAMRKDVLAKCYGGDIS
                     RKRKLLEKQKEGKKRMRQIGNVEIPQKAFMSVLKLDEE"
     gene            11113..12408
                     /gene="hemW"
                     /locus_tag="ACZPCR_02305"
     CDS             11113..12408
                     /gene="hemW"
                     /locus_tag="ACZPCR_02305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HIR1229755.1"
                     /translation="MKSRKKEDLSCLELYIHIPFCVRKCAYCDFLSFPSGEEERERYV
                     ERLTEEIEEAGAVSEGYVATAIFFGGGTPSVLTPKQTERILEAMKKSFYVAEDAEITT
                     EVNPGTADREKLAAWRQAGINRLSFGLQSTENRELQYLGRIHTMEDFLESYRAAREAG
                     FENINIDLMSALPGQTVSSWEKTLRTVVSLQPEHISAYSLIIEEGTPFCQLFGEDGDA
                     AEEKKRRQSLGIPELPDEDAERRMYYDTERILGEAGYHRYEISNYAKPGYECRHNKGY
                     WTGTEYLGLGLGASSYINIRREKGEAAKISASGKESGDRRQLERRSNVRDFKTYLSLT
                     REDFRAGRQIEERDLLTSQAQMEEFMFLGLRLTEGISEAEFLRRFSCALETVYGDVLE
                     ELARQELMERYEREGAAFWRLTKRGIDVSNCVLAEFLME"
     gene            12549..13295
                     /locus_tag="ACZPCR_02310"
     CDS             12549..13295
                     /locus_tag="ACZPCR_02310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HIR1229756.1"
                     /translation="MVQYLIVCPLVFLAGLMDSIAGGGGLISLPAFMIAGIPAHLSLG
                     SNKMCSVMGTVVSTARFAKNGFINFKTSVWFAAAALIGSSIGSHLILMVSEGIIEKLM
                     LVILPVVAVYVLWNKNLGDDSKAGTISAGRKFAVSLAAAFIVGTYDGFYGPGTGTFLI
                     LILTGAARYTMKEAAGTTKVINLASNAAAFATFLLNGKVLIPLGFISGLFCILGHYIG
                     SGLVLTNGKKIVRPVVLIVLAILFVKVLMG"
     gene            13397..14356
                     /gene="prmA"
                     /locus_tag="ACZPCR_02315"
     CDS             13397..14356
                     /gene="prmA"
                     /locus_tag="ACZPCR_02315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HIR1229757.1"
                     /translation="MKWKKFTLTTTTAAVDLVSSMFDEIGIEGIEIEDNVPLTEKETK
                     GMFIDILPELPPDDGTAKVSFYLDDDADVEGILAQVKEGLEELKLFVDLGTCEIEASE
                     TEDKDWINNWKQYFKPFTVDDILIKPTWETIPEEHKDKLLIQIDPGTAFGTGMHETTQ
                     LCIRQLRKYVTPETKLLDVGTGSGILGIAALKLGAREVFGTDLDENAITAVGENLESN
                     DIGADRFTVVQGNIIDDKAIQDQAGYECYDVAVANILADVIIMLQKEIPVHIKKGGIF
                     ITSGIINMKEEAVREAFAANDAFEVVEVTYQGEWVSVTAKRVK"
     gene            14375..15118
                     /locus_tag="ACZPCR_02320"
     CDS             14375..15118
                     /locus_tag="ACZPCR_02320"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HIR1229758.1"
                     /translation="MYHFFVERSQIHPESVTITGPDVNHIKNVLRMKPGEQVLISNGE
                     DRDYLCRLTEISADAVEAEILEEREETTELPAKIWLFQGLPKSDKMELIIQKAVELGA
                     YQIVPVATKRAVVKLDKKKEEAKLKRWNAISESAAKQSKRLIIPEIAPVMSFDEALAF
                     VKDFDSRCIPYECASGMDSVRQFVEQTGPGQKIAVFIGPEGGFEETEIEKAREAGVVP
                     VSLGKRILRTETAGLALLSVLAFHLEGGL"
     gene            15145..16299
                     /locus_tag="ACZPCR_02325"
     CDS             15145..16299
                     /locus_tag="ACZPCR_02325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003508153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HIR1229759.1"
                     /translation="MEAYFDNSATTRVFDCVKDAVVNAMTVDYGNAAARHMKGVEAER
                     LIKEARAEIAKSLKVQEKEILFTSGGTESNNTALIGAAFANQRAGKHLITTGVEHASI
                     YNTMEFLREQGFEITYLPVDSYGCISLEELAQAVREDTILVSVMYVNNEIGAVEPVEE
                     ISKVIKAKNPKTLFHVDAIQAYGKYVIRPKKQGIDLLSVSGHKIHGPKGVGFLYIDEK
                     AKVRPILFGGGQQKGMRSGTENVPGCAGLGAAVREVYRDHEAKIEKLYQIRERLIAGL
                     KELPGVTINGHEGRENAPQIVSASFEGVRSEVLLHALEDRGVYVSSGSACSVNHPGVS
                     GTLKGIGVKKELLDSTIRFSFGLFNEPEEADYCLEVLRELLPVLRRYRAK"
     gene            16341..17516
                     /gene="thiI"
                     /locus_tag="ACZPCR_02330"
     CDS             16341..17516
                     /gene="thiI"
                     /locus_tag="ACZPCR_02330"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003508145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HIR1229760.1"
                     /translation="MFQSFLIKYAEIGLKGKNRYVFEDALMKHIRRSLKELEGTFAVT
                     KESGRIYVEAKSEFDYDEVVEALQRVFGIAAICPVMRVEDLGFEELKNQVVSYIRAAY
                     KEQNFTFKVNCRRANKQYPVHSDEMNRELGSIILDTFPETKVDVHNPQVLLNVEVRSK
                     INIYSLVIPGPGGMPVGTNGKAMLLLSGGIDSPVAGYMISKRGVIIEAVYFHAPPYTS
                     ERAKQKVIDLAKQVARYSGPIKLHVVNFTDIQLYIYDKCPHEELTIIMRRYMMKIAED
                     LAKKDECLGLITGESIGQVASQTVHSLAVTNEVCTLPVFRPVIGFDKQDIVDISQKIG
                     TFETSIQPYEDCCTIFVAKHPVTKPNLDLIRRSEKKLAEGIEEMIKTAEETAEVIWC"
     gene            17565..18335
                     /locus_tag="ACZPCR_02335"
     CDS             17565..18335
                     /locus_tag="ACZPCR_02335"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229761.1"
                     /translation="MKFWREKRKLCIIAALTALLISAGLIWAGRRSSELSVSTEEICS
                     NLSSQSSFSFIKTSLHKTIRGTVEEDTIKFTYLSEPTEALQAAAFDPDTGETDLQYSE
                     YHIRQEDGWLFCRYKDGRWEESRPEEFSPEDFLKRVSFSIDGVDLAVIDKWNYVRTEE
                     LGERKARLFKGTCPVEEYLKAKTELAGYKYFGVSDQSGDLGEIEAEIWIDKDSDEVLK
                     LRYDITRARKQYQEGMRIDVTEVTLSDEIVPFALPEEL"
     gene            complement(18413..18646)
                     /locus_tag="ACZPCR_02340"
     CDS             complement(18413..18646)
                     /locus_tag="ACZPCR_02340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007593716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HIR1229762.1"
                     /translation="MKTVRISLNSIDKVKSFVNDLAKFDVDFDLVSGRYVIDAKSIMG
                     IFSLDLSKPIDLNIHSETQVDEILTVLAPYIVE"
     gene            18869..19747
                     /locus_tag="ACZPCR_02345"
     CDS             18869..19747
                     /locus_tag="ACZPCR_02345"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012993.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HIR1229763.1"
                     /translation="MEEKKRIKIALGEFGTGSGSQELFEKLSDKMAREAARAGAKILC
                     LPELSACGYFIRREELLAAALTAGEQGEKMAATAKKYGISLIFGYPERDGETIYNSCL
                     AVGADGSCIQNIRKVNLWKSEKKRFSEGRDFPVFETCAGRTAAVLCYDLEFPEPARIV
                     SMNGARLIFCPAAWSFAAERRWEVDLASAALCNLAFTAGANYRDENCCGGSCVYGPDG
                     RQRSPEKEIPIELSGAGESRLLIFELDLDETEKERGKVPYYEDWKGELYGNLMKEAWE
                     KRKQSGSLFSSGLSPS"
     gene            19848..21161
                     /gene="mtaB"
                     /locus_tag="ACZPCR_02350"
     CDS             19848..21161
                     /gene="mtaB"
                     /locus_tag="ACZPCR_02350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007867586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035598 - tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HIR1229764.1"
                     /translation="MRKAALHNLGCKVNAYETEAMQQMLEDAGYEIVPFKEGADVYVI
                     NTCSVTNVADKKSRQMLHRAKKMNPSAVVVAAGCYVQAAGEELLKDEAVDIVVGNNRK
                     QDLVSILDQYFAEHQGVENIIDIGKTGEYEPLHIRKISDHTRAFIKVQDGCNQFCSYC
                     IIPYTRGRVRSRQMEDVVREVEELAASGYKEIVLTGIHLSSYGVDFKEENIGLLDLIV
                     RLDQVPGVERIRLGSLEPRIITEEFAGTLAGLKSFCPHFHLSLQSGCDETLKRMNRHY
                     TTEDYAHRCEILRKYFENPAITTDVIVGFPQETEEEFETTREFLRRIHFYEMHVFKYS
                     RREGTRAAVMEGQVPEQEKNRRSDILLDLEAELSSAYRRSFLGKEEEVLLEERVSAEG
                     RDYMIGHTRQYVKAVVPYREGLKNVTVRGKLERMVTDEILFLAEE"
     gene            21256..21519
                     /locus_tag="ACZPCR_02355"
     CDS             21256..21519
                     /locus_tag="ACZPCR_02355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007708776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HIR1229765.1"
                     /translation="MGDMKNTQFFKTVQDDTKLEVSQVLEQVYFALTEKGYNPINQIV
                     GYIMSGDPTYITSHKSARSLIMKVERDEILEELMKNYVETRLR"
     gene            21760..22182
                     /gene="ruvX"
                     /locus_tag="ACZPCR_02360"
     CDS             21760..22182
                     /gene="ruvX"
                     /locus_tag="ACZPCR_02360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007708777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HIR1229766.1"
                     /translation="MRIMGLDFGSRTTGVAVSDPLGITAQGVETIVRKDENKLRQTCA
                     RIEALIKEYEIEEIVLGYPKNMNNTAGERAEKTEAFKAMLERRTGKPVILWDERLTTI
                     AAERVLMESGVRRENRKAVVDKIAAVLILQGYLDSRSV"
     gene            22217..22510
                     /locus_tag="ACZPCR_02365"
     CDS             22217..22510
                     /locus_tag="ACZPCR_02365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007867576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HIR1229767.1"
                     /translation="MNDMFDKIDEMENKITLQSEDGEPIDFYVLEETKLNGENFLLVT
                     DSKEGDGECYLLKDISKPEDAEAVYEFVEEDGELDYLSRIFNELMGDMGIEIE"
     gene            22532..24199
                     /locus_tag="ACZPCR_02370"
     CDS             22532..24199
                     /locus_tag="ACZPCR_02370"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008395837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0004534 - 5'-3' RNA exonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HIR1229768.1"
                     /translation="MKKDTKNNKVKIIPLGGLEQIGMNMTAFEYEDSIIVVDCGLAFP
                     SDDMLGIDLVIPDVTYLKNNINKVKGFVITHGHEDHIGALPYVLKDVPAPVYGTKLTI
                     GLIEHKLKEHNMLRTIKRKVVKHGQSINLGCFRVEFVKTNHSIVDASALAIFTPAGII
                     VHTGDFKIDYTPVFGEPADLQRFAELGKKGVLALMCDSTNAIRPGFTMSERTVGKTFD
                     AIFSEHQNNRIIVATFASNVDRVQQIISSACKYGRKVVIEGRSMVNVIGTASELGYID
                     IPEGTLIDIENLKNYRPEDTVLITTGSQGESMAALSRMAASLHRKVSIMPGDVVILSS
                     TPIPGNEKAVSRVINELSMKGAEVINQDTHVSGHACQEEIKLIYSLVRPKYAIPVHGE
                     YRHLMAQKKLAESMGIPKENVIVMSSGDVIEIGDEGYKTVDHVQSGGILVDGLGIGDV
                     GNIVLRDRQNLAQNGIIVVVLTLEKYSNQLLAGPDIVSRGFVYVRESEDLMDEAQAIV
                     DAAVQDCLKRHVSDWGKIKNIIRDSLSDFLWKRMKRNPMILPIIMEV"
     gene            24247..24663
                     /locus_tag="ACZPCR_02375"
     CDS             24247..24663
                     /locus_tag="ACZPCR_02375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006773407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HIR1229769.1"
                     /translation="MSRRTREINRVTGGIISISLKLILLALVCILMYEGVTRGYSFGH
                     EIFAPAPMAQGEGVSRQVTVEKGMSAMETGKLLKAQGLIPNEYVFAIEASLYEYEIHP
                     GTYTFNTAQTSMDMLQMLDDSPGVSDEETEEKEEKE"
     gene            24660..25334
                     /locus_tag="ACZPCR_02380"
     CDS             24660..25334
                     /locus_tag="ACZPCR_02380"
                     /EC_number="2.1.-.-"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008171 - O-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HIR1229770.1"
                     /translation="MIVNERLTSYLHSLDRGNGELLDRIEAEAVRDFVPIIRKETGAL
                     LKTLVALKQPRAILEVGTAVGYSALLMGRAMPAGCHLTTIEKYEKRLPIARENFRRAG
                     MEDRITLLEGDAEEILAGLTGTWDFIFMDAAKGQYLHWLPMLLRLMPEGGVLISDNVL
                     QDGDLIESRYAVERRNRTIHSRMREYLYALTHMEELETSVLPIGDGVTVSVKKSAGRQ
                     TDPAES"
     gene            25352..26611
                     /locus_tag="ACZPCR_02385"
     CDS             25352..26611
                     /locus_tag="ACZPCR_02385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008395834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HIR1229771.1"
                     /translation="MRELELLIPAGSLDVLKTAVIYGADAVYIGGEAFGLRAKAKNFT
                     KEDMKEGIAFAHERGVKVYVTANILAHNEDLPGVEEYFEEMKEVRPDALIISDPGVFA
                     IARKILPDMELHVSTQANNTNYGTFLFWYNQGAKRVVTARELSLKEIKEIRDRIPEDM
                     EIESFIHGAMCISYSGRCLLSNYFVGRDANQGACTHPCRWKYSVVEETRPGEYMPVYE
                     NERGTYIFNSKDLCMIEHIPEMIEAGIDSFKIEGRMKTALYVATVARTYRKAIDDYLE
                     SPEKYRANMEWYKAEIGKCTYREFTTGFYFHKPDATTQIYDSNTYVKNYTYIGTVETV
                     FEDGSFQMEQKNKFTVGETIEIMKPDGRNLAVTVEEIRNEEGEQMESAPHPKQILRVR
                     LSETPKAYDILRRSEQNEEKEAEQSAC"
     gene            26709..27536
                     /locus_tag="ACZPCR_02390"
     CDS             26709..27536
                     /locus_tag="ACZPCR_02390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HIR1229772.1"
                     /translation="MNWILEAAAGLCLLYYGALVAFTGFSFSFSLFWPLCAAVLGLFA
                     VGRRYYAGHREQIPVWAAVAAVTAAGAVLAVLLTAAALIGTGILTATKNSMDYVIVLG
                     AKVEGREPSRTLKKRLDQAIEYAERNPNTFLVLSGGKGEDEEISEAQAMYEYLRFNGV
                     PENQLLLEMRSTNTVENIQYSLEAIRKQENWKDSVFRQIFGDVAQNAYSPGDDLDSIH
                     IGILTSDFHLFRAKAIARKQGVKNVYGIAAPTDIGLAPNLWIRECFAILKNKFMGNI"
     gene            27584..30505
                     /locus_tag="ACZPCR_02395"
     CDS             27584..30505
                     /locus_tag="ACZPCR_02395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006773397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HIR1229773.1"
                     /translation="MRQIADLESYLLKEERYVEELHSKGYILEHKKTGARIFLLSNDD
                     ENKVFCIGFRTPPSDSTGVAHILEHSVLCGSEKFPVKDPFVELVKGSLNTFLNAMTYP
                     DKTVYPVASCNEKDFQNLMDVYMDAVLHPNIYKEEKIFRQEGWHYEMESEDSPVTLNG
                     VVYNEMKGAFSSPESVLDRYTRNVLYPDTCYSCESGGDPAVIPELSYEDFLNFHKTYY
                     HPSNSYIYLYGDMDMAEKLDWLDREYLSRYDRLEADSRIRSQKAFAAPREREIFYPIT
                     ESESEENSTYLSVSSVVGEPLNPIHYLAFQVLEYVLIDAPGAPLKTELLNAGIGQDIL
                     GGYENGILQPYFSVIAKDANREQKGEFLAVVQGTLRRLADQGLNKKSLLAAINYYEFR
                     SREADFGSFPKGLMYGLQCLDSWLYEGDPLLYLEYEEAFAFLKKSIEEGYFEDLIRTW
                     LLDNPSTAVILVSPKKNMTAEEDKKLEEKLAAYRETLTQEQRIALAQATKELKEYQDA
                     SSPKEDLEKIPLLRREDINPEPEKLILEEREEEGVKVLFHNIFTSGIGYVKVLFNTDR
                     IPQEDMVYAGLLKAVLGAVSTKHYSYGELADEINLNSGGVNFSIVSYPSLEDPDQFTG
                     MFAGTARVLYEKLDFGFSILGEILTSSVLDDEKRLLEIINETKSRAQMRLNSAGHSAA
                     VARATSYFSPSSAYGDVTGGIAFYQFLEDLAKNFEERKKTLIEKLKETAKRLFTTDNL
                     AVSFTADEKGYGEMKQSLKLLTGILPETGGERYTFTCDKENKNEGFMTSSQVNYVARC
                     GSFAESGLPYTGALRTLKVILGYDYLWLNVRVKGGAYGVMNGAGRTGEGYFVSYRDPN
                     LKETNQVFENVVKYLEEFDADERDMTKYVIGTISDLDVPLLAPYKGSKADAAYFSHLT
                     DEMIKKEREEILKATKEDIRALAPVIREILSTGSFCVIGNAEKIRENQELFGEVKNLF
                     N"
     gene            30527..31432
                     /gene="era"
                     /locus_tag="ACZPCR_02400"
     CDS             30527..31432
                     /gene="era"
                     /locus_tag="ACZPCR_02400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002577941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HIR1229774.1"
                     /translation="MEQNFKSGFVTLIGRPNVGKSTLMNHLIGQKIAITSDKPQTTRN
                     RIQTVYTDERGQIIFLDTPGIHKAKNKLGEYMVSVAEHTLQEVDVILWLVEPTTFIGA
                     GERHIAEQLKKVKTPVLLVINKIDTVKNKEDILTFIAAYKDICSFSEIIPVSALKEIN
                     VEDVKDSIFKYLPYGPQFYDEDTVTDQPMRQIAAELIREKALRMLDDEIPHGIAVTIE
                     RMTERKNGMIDIEATIVCERDSHKGIIIGKGGSMLKKIGTSARMEIGNLMDTQVNLKL
                     WVKVRREWRDSDLYMKNYGYNPKDI"
     gene            31454..32101
                     /gene="recO"
                     /locus_tag="ACZPCR_02405"
     CDS             31454..32101
                     /gene="recO"
                     /locus_tag="ACZPCR_02405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002577942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HIR1229775.1"
                     /translation="MRELISATGMVLSASPVGDYDKRLVILTKERGKITCFARGAKRA
                     SSQLRAPSRPFVFGVFTMSEGRDAYNLYSAEVENYFEELSKDMECACYASYFAEFAGY
                     YGRENVDESENIRLLYQSYRALLKPGIPNKLVRRIFELRLMTIEGEYRELPERAVSDS
                     AAYAWQFVISTPIEKLYTFLLTEPVFEEFSRCVEDNKRRYVDREFRSLEILKVVT"
     gene            32231..32866
                     /locus_tag="ACZPCR_02410"
     CDS             32231..32866
                     /locus_tag="ACZPCR_02410"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229776.1"
                     /translation="MMRKARLILAAAAAGALLTGCSGGKSAFSPEQSCVYVSGDGTLR
                     SALVLESEEDFEESELKEFLEGAVSRFNEKRGGDGEEGPVTLASCTADQGVMTAVFEY
                     RDADALVSFRQSDENEDNSNTFSNIEVKSAAEAGTAGWLSGEFIKADGSQASGLDAAK
                     EKRAAAVSVQGGGVLETEGELLYVSAGAQILDSTSVKLPDGETSVVVFKEK"
     gene            32889..34277
                     /locus_tag="ACZPCR_02415"
     CDS             32889..34277
                     /locus_tag="ACZPCR_02415"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012739580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase"
                     /protein_id="HIR1229777.1"
                     /translation="MEKTMEKIVALAKSRGFVYPGSEIYGGLANTWDYGNLGVELKNN
                     VKKAWWQKFVQESPYNVGVDCAILMNSQTWVASGHLGGFSDPLMDCKSCKERFRADKL
                     IEDYMAENNIEMEGSVDGWSQEEMKKYIDDHNICCPSCGKHDFTDIRQFNLMFKTFQG
                     VTEDAKNTVYLRPETAQGIFVNFKNVQRTSRKKIPFGIGQIGKSFRNEITPGNFTFRT
                     REFEQMELEFFCEPGTDLEWFAYWKQYCIDWLQNLGIKPDEMRARDHSPEELCFYSKA
                     TTDLEFLFPFGWGELWGIADRTDYDLTQHQNVSGQDMTYFDDEKKEKYIPYVIEPSLG
                     ADRVTLAFLCSAYDEEEIGEGDVRTVLHFHPAIAPVKVGVLPLSKKLNEGAEKVYAEL
                     SKYYNCEFDDRGNIGKRYRRQDEIGTPFCVTYDFDSETDGAVTVRDRDTMEQVRVPIT
                     ELKSYLEDKFRF"
     gene            complement(34575..35972)
                     /locus_tag="ACZPCR_02420"
     CDS             complement(34575..35972)
                     /locus_tag="ACZPCR_02420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009242177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1229778.1"
                     /translation="MKENKDFLGTEPVGKLLRSLALPTVAAQLINMLYNIVDRIYIGH
                     IPGDGPMALTGVGVCMPIIMIVSAFAALVSTGGAPRASISMGRGDQKSAENILGNCFC
                     LQLLVSAVLTAVLLIWNRDFLMAFGASENTISYAVSYMNIYAVGTIFVQLTLGMNAFI
                     TAQGFAKIGMLSVLIGAVLNIVLDPIFIFGLGMGVRGAAAATVLSQAVSCIWVLSFLM
                     GKKTFLRIRAKYMRLNPKVFLPCIALGLATFIMQSSESVISVCFNSSLLNYGGDIAVG
                     AMTILTSVMQFAMLPLQGLGQGAQPIISYNYGAGNKSRVKKAYFLLLKSSLFYSCLLW
                     GGIILFPTGFASIFTSDPQLVEFSAMALRIYMAVMFIFGIQMACQMTFTSIGNAKASI
                     SVAVVRKFVLLLPLIYLLPRILPMDQTKAVYLSEPIADTLAVTFTVILFTFQFRKALR
                     ALEEDKQFPIAHVLK"
     gene            complement(35980..36537)
                     /locus_tag="ACZPCR_02425"
     CDS             complement(35980..36537)
                     /locus_tag="ACZPCR_02425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008374260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HIR1229779.1"
                     /translation="MSLRMSAAFRLGKPAVKRGGASMNSRTELLFGIRRIVKFYELLL
                     KPVCLQYGLSHMEAEILAFLHNNPGRDTASDIVELRMFKKGNVSQAADSLIERGFLTR
                     ERDLGDRRKSHLHLTEASQEILREIERARLSFQAQLFSGFSEDEYQLFQSLNSRIFEN
                     ALTGLENKGGHTKHKSRIQSSNSKE"
     gene            36744..38069
                     /locus_tag="ACZPCR_02430"
     CDS             36744..38069
                     /locus_tag="ACZPCR_02430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1229780.1"
                     /translation="MGQNTGNLLEGPIKALYRKYLFPSISATLVTSIYILADTMMIGR
                     GVGPVGIAALNLLLPVFSLFFGTGMMFGVGGSVLFSISRGRKEEAMCRRYFTAALFLA
                     LSVGIIYGAGFLFFFDPVTKFLGRNESMDLFVRQYGKILIAGAPIFVCSSFFQAFVRN
                     DSEPKRAMAAVITGGVSNVILDYVFIFPLDLGMAGAAAATVIGSLITVVILLTHFVSP
                     ANTLRLARRFGFREMRVAAVNGASSFLVEMTSGIVVFLFNRQLLSYVGDLGVVVYGIV
                     SNSALIASSIFNGISQAAQPVMAMNFGAGKHSRVEDTRRMALKTAAAAGVLFTAIGLF
                     CPEMLVYAFVEPTEEIMAMGVTAVRIYFLSFLAAGSNVLFATYFQSVLKPGFAMTICM
                     LRGIVLNAVFVFLLPMVFGVNGIWAAMTVTECATLLCAFLMLKRGRKTA"
     gene            38239..40866
                     /gene="ppdK"
                     /locus_tag="ACZPCR_02435"
     CDS             38239..40866
                     /gene="ppdK"
                     /locus_tag="ACZPCR_02435"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013271629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050242 - pyruvate, phosphate dikinase
                     activity [Evidence IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HIR1229781.1"
                     /translation="MANKWVYLFSEGDATMRNLLGGKGANLAEMTKLGLPVPQGFTIT
                     TEACTQYYEDGRKINDEIMAQIMDHISKMEEITGKKFGDKENPLLVSVRSGARASMPG
                     MMDTILNLGLNEEVVEVLAKKSGNPRWAWDCYRRFIQMFSDVVMEVGKKYFEELIDKM
                     KTEKGVTQDVELTAEDLKELADQFKAEYKEKIGEDFPTDPKTQLMEAIKAVFRSWDNP
                     RANVYRRDNDIPYSWGTAVNVQMMAFGNMGETSGTGVAFTRDPATGEKHLMGEFLMNA
                     QGEDVVAGVRTPQKIDQLKEVMPEVYEQFVGICHTLENHYRDMQDMEFTIEDKKLYML
                     QTRNGKRTAKAALKIACDLVDEGMITEEKAVTMIDPRNLDTLLHPQFDAKALKEAAPV
                     AQALAASPGAACGKIVFTAEDAKEWALKGEKVVLVRLETSPEDIEGMKAAQGILTVRG
                     GMTSHAAVVARGMGTCCVSGCSEIAMDEANKKFVLAGKEYHEGDWLSIDGSTGKIYDG
                     VIPTVDASIVGEFGRIMAWADKYRRLKVRTNADTPADAKKARELGAEGIGLCRTEHMF
                     FEGDRIDAFREMICSDTVEEREAALEKILPVQQGDFEKLYEALEGNPVTIRFLDPPLH
                     EFVPTEEEDIKKLADAQGKTVEQIKTIIDSLHEFNPMMGHRGCRLAVTYPEIAKMQTK
                     AVIRAAINVQKAHADWTVKPEIMIPLVGDVKELKYVKKAVVETADAEIAAAGVDLKYE
                     VGTMIEIPRACVTADEIAKEAEFFCFGTNDLTQMTYGFSRDDAGKFLNAYYDAKIFEN
                     DPFAKLDQDGVGKLMEMAIKLGKPVRPELHVGICGEHGGDPSSVEFCHKIGLDYVSCS
                     PFRVPIARLAAAQAALNNK"
     gene            complement(40983..41816)
                     /locus_tag="ACZPCR_02440"
     CDS             complement(40983..41816)
                     /locus_tag="ACZPCR_02440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004847319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HIR1229782.1"
                     /translation="MKPFNVEQGSGKPDMPKSLYSSGEFARLNGVNKRTLHYYHEIGL
                     FHPAVIGENGYHYYTCFQSVELELIRMLGKLGVPLETIKSYREHPSHTSFSQIAMHQK
                     QLIDHSMEQLMAARAFLQKKSDKLELGMKARHGSVELVSLPAQPILLSSPISGRYDEK
                     DFSTAAEFSLRLRSIFGLFDSFGSRMCLESGKEEHCFFAYGSENSSEQDEIRPAGTYI
                     RAFCIGTWDKLEEVYETIHDFAKSRQLKLSPYSYEEGLNEMALEKAEDYITMITIGCE
                     G"
     gene            41901..42449
                     /locus_tag="ACZPCR_02445"
     CDS             41901..42449
                     /locus_tag="ACZPCR_02445"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009242466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1229783.1"
                     /translation="MKFINEKQFQKKDWKQVKDIYCEAFPKCERKPFFMLKHSVRTGK
                     VQMLAAMEGELLLGFLAAVPYEDMVMVDYLAVSDKIRSKGTGSRLLQELCSRFAEKKV
                     VLLIERPDVPAENINQRLARRKFYFKNQFTSSGIYINGAGGEMEVLNFGGTVSGQEYM
                     KLQKYALGRLLFAMSGIALASE"
     gene            42486..43358
                     /locus_tag="ACZPCR_02450"
     CDS             42486..43358
                     /locus_tag="ACZPCR_02450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016852 - sirohydrochlorin
                     cobaltochelatase activity [Evidence IEA];
                     GO_process: GO:0019251 - anaerobic cobalamin biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sirohydrochlorin cobaltochelatase"
                     /protein_id="HIR1229784.1"
                     /translation="MSCTHNKKQDETEDTSLENTRNQDGIGEKELLVASFGTSYQDTR
                     CRTIGAIEEELERAFPGYSVRRGFTSRMIINRVKTRDQIIIDSLEEALKRAADNKVRH
                     LIVQPTHMMDGFEYTALVNKVGEYSHQFERTAVGKPLLSSEEDFQAVIQALTEETEEY
                     DDGETAFCFMGHGTEAQANQVYRKLQEMFLAAGQENYFIGTVEAEPALEEVLAQVKKG
                     SYKRAVLQPLMIVAGDHANNDMAGEEEGSWKQAFEEAGYEVSCILRGLGELEKIRQLF
                     VKHAKEAESCLLAV"
     gene            43472..44089
                     /gene="rbr"
                     /locus_tag="ACZPCR_02455"
     CDS             43472..44089
                     /gene="rbr"
                     /locus_tag="ACZPCR_02455"
                     /EC_number="1.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016692 - NADH peroxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin"
                     /protein_id="HIR1229785.1"
                     /translation="MESILKNTETAKNLMRAFAGESQARNRYTFAAAAAKKEGLPVIE
                     AVFQFTAAQEQEHAEVFYRFLKEMTGESIQIDAGYPVDGWDKTLDLLKAARHNEFEEY
                     RDVYQNFGNIALDEGFDRIGQIFHMIAEVEKTHGDRFDLLAGLLEKSQLFASEVETGW
                     VCLNCGYVYHGTFAPKYCPVCEHEQGWFIRMELAPYAGAYKRLKK"
     gene            44223..45095
                     /locus_tag="ACZPCR_02460"
     CDS             44223..45095
                     /locus_tag="ACZPCR_02460"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HIR1229786.1"
                     /translation="MTGLGWALFGLTGLGAGFLARSEYEKKHFVTETFELTSEKLREE
                     ERNFVFLSDLHNNQFGKNQEKLLRAIEKVRPDAVLIGGDMMVCKRGKLDLEPSLDLVR
                     TLAGKYPVFYANGNHEERMKREREVYGDSCQTFCQELEKAGVMYLSDESAEFGDDIRI
                     TGCNMQERYYRHRFTVPRMEEGELESHVGRGESGRYQILLLHSPLFFEECRRWGADLT
                     LCGHFHGGTIRLPFLGGVMTPQFQFFLPWCAGRFDREGKTMIVSRGLGTHSINIRFCN
                     KPQLVHIRLRKKQG"
     gene            complement(45106..45981)
                     /gene="sdaAA"
                     /locus_tag="ACZPCR_02465"
     CDS             complement(45106..45981)
                     /gene="sdaAA"
                     /locus_tag="ACZPCR_02465"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009220943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HIR1229787.1"
                     /translation="MDFKNGNELLELCESCGLPISQVMKQRECELGETSQEAVEARML
                     RALEIMKESAHSPLTAPKKSMGGLIGGEARLVNERRLAGKSAAGSVLSRAIAFSMAVL
                     EVNSSMGLIVAAPTAGSSGIVPGLLLALQEEYHFSDSQILDALFNAGAIGYLAMRNAT
                     VAGAVGGCQAEVGVASAMAASAAVELMGGSPVQCLDAASTVLMNTLGLVCDPIGGLVE
                     CPCQGRNAAGAANALTAAEIALSGVRQLIPFDEMLDAMYAVGRRLPQELRETAMGGCA
                     VTPSGCSAFCSGCMD"
     gene            complement(45998..46666)
                     /gene="sdaAB"
                     /locus_tag="ACZPCR_02470"
     CDS             complement(45998..46666)
                     /gene="sdaAB"
                     /locus_tag="ACZPCR_02470"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009204214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HIR1229788.1"
                     /translation="MTFISVFDVLGPNMIGPSSSHTAGAASIALMARKMFGCPVLKAD
                     FTLYGSFAKTYRGHGTDRALLGGIMGFSTDDKRIPDSFSIARERGIEFSFTPNEIETE
                     VHPNTVDIAMTGSSGRRMTVRGESLGGGKIRITRINQAEVDFSGEYNTLIVIQKDRQG
                     VIAHITGCLSKANVNIAFLKLFREAKGSTAYSIVEFDGSLPEGIPDEIRKNPNVKDVM
                     LIEL"
     gene            46953..47747
                     /locus_tag="ACZPCR_02475"
     CDS             46953..47747
                     /locus_tag="ACZPCR_02475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="segregation and condensation protein A"
                     /protein_id="HIR1229789.1"
                     /translation="MGISYKLEHFEGPLDLLLHLIEKNKVSIYDIPIVTITEQYLDYV
                     NHMDIQDLDLVSEFLVMAATLLDIKARMLLPREEKEEEEEEDPRAELVRRLLEYKMYK
                     FMARELEDMEEDAERLLFKAPTIPREVAEYEAPVDLDELLKGLTLAKLQEIFESVIRR
                     GENKKDPVRSGFGTIAREPVSLKKRLAFVLGFARRNRKFSFREMLGGTAGKMETVVTF
                     LAVLELMKVGKIYLTQETVDSDMYIESLEPEGTYEEIDFDVPGTAE"
     gene            47812..48531
                     /gene="scpB"
                     /locus_tag="ACZPCR_02480"
     CDS             47812..48531
                     /gene="scpB"
                     /locus_tag="ACZPCR_02480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HIR1229790.1"
                     /translation="MREKDRLLRQEAAAEAVLFTMGRAVELRELSAALETGEEEAQAA
                     VERLREKYREEGRGLSIIELSGSFQMCTKAEYYENLIRVAKAPKKQALSDVVLETLSI
                     IAYKQPITKIEIEQIRGVKSDHAVNRLIEYNLVYEVGRLDAPGRPALFATTEEFLRRF
                     GVGSMEELPVIDPEQLDEFKLEVEEELQMNDEELQAVLEAAASAESGTEKSPEGKAGE
                     TAKEKPGEKAEGQTGGQAKEP"
     gene            48800..50932
                     /gene="nrdD"
                     /locus_tag="ACZPCR_02485"
     CDS             48800..50932
                     /gene="nrdD"
                     /locus_tag="ACZPCR_02485"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HIR1229791.1"
                     /translation="MKCAEIKVIKKDGTREDFNVQKVVVAVNKSAERAMIQFSQAELN
                     FICQFVEEKAQELGVAEIPIARMHNLVEGALERVNPLVAKSYRDYRNYKQDFVQMLDE
                     VYKKSQSIMYIGDKENSNTDSALVSTKRSLIFNELNKELYKKFFMTVEELQACRDGYL
                     YIHDMSARRDTMNCCLFDVKTVLTGGFEMGNLWYNEPKTLDVAFDVIGDIVLSAASQQ
                     YGGFTVPSVEEILAPYAEKSYAKYIEKYEGLGLSREKAEEVAWADIQRDMEQGFQGWE
                     YKFNSVSSSRGDYPFITMTAGTGKSRFAKMATITMLDVRRKGQGKDGHKKPVLFPKLV
                     FLYDENLHGPGKELEDVFEAGIRCSSKTMYPDWLSLTGEGYIASMYKKYGRIISPMGC
                     RAFLSPWYEKGGMEPADETDVPRFVGRFNVGVVSLHLPMILAKARQESRDFYEVLDYY
                     LELIRKIHIRTYAYLGEMRASTNPLAYCEGGFYGGHLGLHDKIKPLLKTATASFGITA
                     FNELQELYNGKSLVEDGQFALEVLEHINEKVNQFKKEDGNLYAIYATPAENLCGLQVK
                     QFRKKYGIIENVSDREYVSNGFHCHVTEDITPIQKQDLEYRFWELSNGGKIQYVKYPI
                     AYNTDAIRTLVRRAMKMGFYEGVNLSLSYCDDCGHEELNMDVCPKCGSRNLTKIDRMN
                     GYLSYSRVKGDTRLNDAKMAEIAERKSM"
     gene            50976..51467
                     /gene="nrdG"
                     /locus_tag="ACZPCR_02490"
     CDS             50976..51467
                     /gene="nrdG"
                     /locus_tag="ACZPCR_02490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006568180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HIR1229792.1"
                     /translation="MRYHNITKDDMLNGDGLRTVLWVAGCCHGCKGCQNPVTWDIEGG
                     LPFDGEARAELFAELEKPYISGVTLSGGDPLHPANREETGALMKEMKERFPDKTIWLY
                     TGYDWDQVKDLPYIGFADVLVDGRFVEELKDEDAFWRGSTNQRVIDVKKSLESGNVTL
                     HCR"
     gene            51648..52079
                     /locus_tag="ACZPCR_02495"
     CDS             51648..52079
                     /locus_tag="ACZPCR_02495"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004170 - dUTP diphosphatase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006226 - dUMP biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0046081 - dUTP catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HIR1229793.1"
                     /translation="MKIRIKYFTDKIDRLCYIDGKSDWMDLRAARDVELKAGEFALIP
                     LGVAMELPKGYEAHVVPRSSTFKNFGVIQTNHMGVIDETYCGDNDQWFFPAYALRDTV
                     IHVNDRICQFRIMEHQPSFSFEETDCLGNQDRGGHGSTGTK"
     gene            52152..53087
                     /locus_tag="ACZPCR_02500"
     CDS             52152..53087
                     /locus_tag="ACZPCR_02500"
                     /inference="COORDINATES: protein motif:HMM:NF025910.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIR1229794.1"
                     /translation="MKRHRLLCRVLAASAAALLLTGCGDSKKAREARMTGIEQMNQEN
                     YEDAIASFDKALDEADGIVGPFELDVLKYRAEAEYLTEDYRAAAHTYDILADVDGEKR
                     EYLYYGAASHALAGELGEAVEAYEKAQKGASGEKKQDQKAQKPADGKKENQKQEDQKG
                     ADGTQQETASGQAALDPDQKSIHEAALSPEEEAGRSLALSAIGKAYEDQGQYEEAMSF
                     YEGAASSGLTADLCNRMGLCMMAAEQYDEALSYFEKGMTLQDEVKMPDLKYNEAAAYE
                     YKGNFEKALELLNAYVSAYGSTPEIEREIVFLESR"
     gene            53115..54362
                     /gene="hflX"
                     /locus_tag="ACZPCR_02505"
     CDS             53115..54362
                     /gene="hflX"
                     /locus_tag="ACZPCR_02505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002600512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HIR1229795.1"
                     /translation="MAELYDMREEEERVILVAVSTGDGDDTEESVDELAELVKTAGAV
                     AADRIIQNRERVHPGTYLGKGKIEEVRERVLALQATGVVCDDELSPAQLRNLEDALQT
                     KVMDRTMVILDIFASHAVTREGKIQVELAQLRYRAARLVGLRNSLSRLGGGIGTRGPG
                     EKKLESDRRLIHERIGQLKAELEDVKRHREVARQQRDRDCTVSAAIVGYTNAGKSTLL
                     NYLTDAGILAEDKLFATLDPTTRMLKLPSGQNILLTDTVGFIRKLPHNLIEAFKSTLE
                     EARYSDIILHVADVSNPQLDTQIHIVYETLRQLEIRDKTIVTVFNKMDKLTGDVILRD
                     FSSDFQVKISAKTGEGIPDLLETLEGILRSRRVYLNKVFSYGEAGKIQSIRKYGELLK
                     EEYTEAGIQVEAYVPAEIYGSLM"
     gene            54506..56905
                     /locus_tag="ACZPCR_02510"
     CDS             54506..56905
                     /locus_tag="ACZPCR_02510"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside triphosphate reductase"
                     /protein_id="HIR1229796.1"
                     /translation="MISVIKRDKETVGFQLTKLTASIEKALQAAGNVCSQEIAELLSL
                     RTTADFQPKICEGELRTEEIKASAARVLEQAGYTEAARAYLSYKKEKNSAEEKKNTLL
                     DYKDVVNSYVKVEDWRVKENSTVTYSVGGLILSNSGAVTANYWLSEIYDSEIAEAHRN
                     ADIHLHDLSMLTGYCAGWSLKQLLLEGLGGITGKITSSPARHLSVLCNQMVNFLGIMQ
                     NEWAGAQAFSSFDTYLAPFVKADHLSYDAVKKCIESFIYGVNTPSRWGTQAPFSNITL
                     DWTVPDDMAEMNAIVGGKEMDFKYKDCKEEMDLINRAFIETMIEGDANGRGFQYPIPT
                     YSITKDFDWSDTENNRLLFEMTSKYGTPYFSNYINSDMQPSDVRSMCCRLRLDLRELR
                     RKTGGFFGSGESTGSVGVVTINMPRIAYLASDEKDFFARLDHMMDVSARSLKIKRTVI
                     TKLLDNGLYPYTKRYLGTFENHFSTIGLVGMNEAGLNARWLRMDMTHRETQEFTKKVL
                     NHMRERLSDYQELYGDLYNLEATPAESTSYRLAKHDRKRYPDIITAGEPGETPYYTNS
                     SHLPVGYTEDIFDALDIQDELQTLYTSGTVFHAFLGEKLPDWQAAARLVRTIAENYKL
                     PYYTLSPTYSICREHGYLAGEHFTCPICGKKAEVYSRITGYYRPVQNWNEGKSQEYKD
                     RKTYCMENSRLKDGRELSEGLETEKKTVKENREAPRKGMGAKAGVYLFTTKTCPNCRI
                     AKECLKGTDYTVVDAEENPDMSSRFGIMQAPTLVLVGKDGEIKKFVNASNIRKFAEEY
                     K"
     gene            56982..58940
                     /locus_tag="ACZPCR_02515"
     CDS             56982..58940
                     /locus_tag="ACZPCR_02515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="HIR1229797.1"
                     /translation="MKKLEERYLERLAELYPTIAAASTEVINLEAILNLPKGTEHFLT
                     DVHGEYEAFSHVLKNGSGSVRRKIDDVFGHTLSRQDKQTLATLIYYPWEKMERILKKE
                     ENPEDWYKITLYRLIEVCRRASSKYTRSKVRKALPKEFAYVMEELITEREELADKESY
                     YGAIVETIIRVGRAKQFIAAMCELIQRLTVDHLHIVGDIFDRGPGPHIIMDKLMTYHS
                     VDIQWGNHDVLWMGAAAGQICCIANVIRICARYGNLDILEDGYGINLLPLATFAMNVY
                     AEDPCACFALKGTNTYAQQEREINLKMHKAISVIQFKAEGQIIRKHPEFGLEGRNLLH
                     RIDYEKGTIDLNGTEYQLLDKNFPTVDPADPYSFTDQEAEIMERLSKAFMGCEKLQRH
                     MKFLLAKGSLYKVYNNNLLYHGCVPLNEDGTLKSVEIYGKKYRGRALYDALDNYVRKG
                     FVAVDRAEREKGRDLMWYIWLSENSPLFGKDKMATFERYFLAEKETHKEVKNPYYRFL
                     ENEEVIDRILREFGLESEGAHIINGHVPVKTKDGESPIKCGGKLLVIDGGFSRAYQEE
                     TGIAGYTLIYNSYGLILAAHKPFESTESAIENESDIHSESTMVKWVAKRKRVGDTDAG
                     RELREKIRDLEGLLEAYYSGAIAEKFTG"
     gene            59061..60035
                     /locus_tag="ACZPCR_02520"
     CDS             59061..60035
                     /locus_tag="ACZPCR_02520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HIR1229798.1"
                     /translation="MAGDETREKRGYAMNLKEQTYVCVLAECGNITKAAERLFISQPA
                     LSIYISTLEKNLGVRLFDRSGKRFTLTWTGEMYVEKARKMLDLKAEFDEGLAEITGER
                     AGRLRIGVQLRRETWLIPPVLARFKSEYPRIQVVIQEGNHKELMQMFNAYELDLVLMN
                     GADVKGGMQAQELFSEELLIAVPQLSPLNEKAVWAEGSRYRYLDLKWLNGQNVILPYP
                     GQSLRADVEAVLKSEGITLGRIETIRNIEMAMQMVAEGLGIGFNREYYAMNMKYRKRV
                     NYYTMGATAPKTAFVAGYRKDIHVTEPMQRFIALCRQQAYTEWESLAQ"
     gene            60141..61328
                     /locus_tag="ACZPCR_02525"
     CDS             60141..61328
                     /locus_tag="ACZPCR_02525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007715609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HIR1229799.1"
                     /translation="MMDKKGMYACIDSKALELTEMADDIFDHPELGLSEFRASGLLTS
                     WLEKEGFQVEKGAGGLETAFKAVFKKGEGGPNIGLLCEYDALPGIGHACGHHMQGPSI
                     LGAAAALKNAGPDGNYTITVYGTPAEESVSGKILMIKNGVNFEELDVALMMHGNGCTQ
                     VDVKSLALSKFKVIYHGVSAHAAVKPEKGRSALDGLILAFQGIEFLREHVADDVKMHY
                     TVVGCGGTPANIVPETAEASFYVRSYNRTYLNTVIERFKKVLQGAAMMTETEVEIIEE
                     KGIDSKIPCLKLNDLIMANAEAVNAPRIRAPREKTGSTDFGNIMHRVPGSCIRVAFVE
                     EGAASHSQDFVNAGKTEEAHQAVVYGAKILAGTAADLIADPKLLAEVKEEFQTRKKQE
                     SSI"
     gene            61345..62748
                     /locus_tag="ACZPCR_02530"
     CDS             61345..62748
                     /locus_tag="ACZPCR_02530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HIR1229800.1"
                     /translation="MSEKTKKPFKMPHTFVIIFTIILAAVALTWIIPAGQYVRFENAQ
                     GIEVIDPNQFNYIDRTPVNPFLIPLYIVKAFIKQIDLMLVILFAGGAFHMITQTGALH
                     AIVAKLAKAFSNRLYIFIPLLTLVFGLICTTQGVNLFIAFAPIMVMLAMAMGLDSITG
                     ASIILLGGAVGFSTGPLNINTTIVAQKIAELPLYSGIGYRFVCFGVFYVVTNIYLLRY
                     AMKIHKNPELSPMYDLDKQSEFKDGADLESFGTMNLRKSLIMIAFFAALIAIVYGGVK
                     LDWDMEETAAMFLGLALVAGVIAGFNPSKISKDFLDGCKKMLGAAFIIGMATAIGTIM
                     KSGNIIDTVVHALAGGLSNVPSILQAPAMLLANTIINVFLTSGSGQAAAVMPIMTPLS
                     DLIGVTRQTAVLAFNFGDGFCNYVLPTSTALMGIIGAANIPYDRWMKFMWKLFLIWLG
                     VGTVLLMIAQVMHYGPM"
     gene            63001..64383
                     /locus_tag="ACZPCR_02535"
     CDS             63001..64383
                     /locus_tag="ACZPCR_02535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008395759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HIR1229801.1"
                     /translation="MEREKFSSRLGFILISAGCAIGLGNVWRFPYIVGQYGGAAFVLI
                     YVAFLLLLGLPIIVMEFAVGRASQKSVALSFDVLEPKGSKWHIQKWFGMAGNYILMMF
                     YTTVAGWLVYYFIKMAKGDFVSLDPAGVSEQFSSMMANPAINVGFMALVVVVCFGVCA
                     MGLQGGVEKVTKIMMVVLLALMVVLACNSIMMENSGPGLEFYLKPDFGKIKEAGIGEV
                     VFAALGQSFFTLSIGIGALAIFGSYIGKERRLTGEAVSVMILDTSVAFMAGLIIFPAC
                     FAYGIEAGQGPSLIFVTLPNVFNNMAGGRFWGSLFFVFMSFAAGSTVIAVFQNIVSFA
                     TDLTGCSVKKAVAVNLVVIILLSLPCALGFNVLSGITPFGSGSTIMDLEDFIVSNNLL
                     PLGSLVYLAFCTSRYGWGFKKFLAEADEGRGIKFPAWARIYISYGIPVIVLYIFIQGY
                     WAKFAPMFMK"
     gene            64775..66466
                     /locus_tag="ACZPCR_02540"
     CDS             64775..66466
                     /locus_tag="ACZPCR_02540"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: protein motif:HMM:NF014763.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor domain-containing diguanylate cyclase"
                     /protein_id="HIR1229802.1"
                     /translation="MIVSLEALAENLQDFSLSQEEEVLRQLSFLAEVGRFSYVGVSDQ
                     EGNIIDSAGQKANIQGRDYFQEAMAGKTVISDVMESKVRGGKAIQVMALPIMEHDGPR
                     GIVFGILNIDSMDEILEGETGSDIDIQIIDSQGNYILRKKKGPFAKKNAWDEFEEYEF
                     IEGNEEEIRENIKAQKAGNLIFKMGEEEQFGYYMPMGLRGYYICSIVNGEKLRQWQKQ
                     VNAEASQMMLLMTAAFFTLGIGPYLYNKKVQEELRRSHAEAVSSEEMMGIAIKESSQV
                     VFEYSIQTGILKKKAGVSFPLFSGSGTEAKVKAVLDRGILAEESVPVFLELFETIKTE
                     ESVEGIFKAEEDGCVKWYRILMKNIYDENHDLLNTVGIVDDVTEKKVQEELLEIGEKE
                     KKALQKQAERDGLTQLYNAAAVKSKVQELLEHADPYSDCHLFVLLDLDNFKQINDTFG
                     HQYGDQVLREVADVLKKTFRRDDILGRLGGDEFVFLLRSVPNFQVMEPIFEKLCRQLQ
                     KTYTKDGKSVTISASLGAACAPGQGSTFTELYSKSDQALYEVKNQLKNGYRLYGN"
     gene            66745..67836
                     /gene="phnW"
                     /locus_tag="ACZPCR_02545"
     CDS             66745..67836
                     /gene="phnW"
                     /locus_tag="ACZPCR_02545"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007709622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HIR1229803.1"
                     /translation="MKNYKLLTPGPLTTTDTVKRVMMFDHCTWDDDYKQITQEIRKNL
                     LKLAHVDEKEYTAVLMQGSGSFGVESVLSSVVPEDGAVLLLSNGAYGERAAKMCGYHK
                     IPCTHVTQEYNRTPDPGKAEEALKSHPEITHVMMIHSETTSGILNDIKTIGELAHTYG
                     KTFIVDAMSSFAGVDIPMKDWQIDFLISSANKCIQGVPGFSFIIADRSLLMETKGRAR
                     SLCLDLYDQWAGMEKDGKWRYTSPTHVVLAFAQAMRELEAEGGIPARHARYQRNMDVL
                     VNNFEELGFKLYVDKTWQGPIIATFLYPEGRKFDFQDMYCYIKDRGYAIYPGKLTDAD
                     TFRIGVIGEIYEEDIEKLTEIMREYMAQA"
     gene            67850..68632
                     /gene="phnX"
                     /locus_tag="ACZPCR_02550"
     CDS             67850..68632
                     /gene="phnX"
                     /locus_tag="ACZPCR_02550"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009254942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050194 - phosphonoacetaldehyde hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HIR1229804.1"
                     /translation="MMKIEGVIFDWAGTTVDYGCFAPVRAFAEIFREYGIEATMEETR
                     KPMGMLKWDHIKTMLSMERINEAWIRVHGRPWTDRDVDEMHDKFAEKLMGILHEYTQV
                     KPFVKEAVKELRRRNIKIGSTTGYTDAMMEIVVPRAAENGYAPDFWISPNSVGNMGRP
                     YPYMIFENMRQLKLSDVRRVIKVGDTVSDVKEGVCAGVISVGVLEGSSELGYSKEEYN
                     ALTEAEKKTAKEKASEKFKEAGADYVIDHMGQLASLIDRLEN"
     gene            68777..69112
                     /locus_tag="ACZPCR_02555"
     CDS             68777..69112
                     /locus_tag="ACZPCR_02555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009295999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HIR1229805.1"
                     /translation="MKMIIAIIGSEDADDLVYELNQNSFFVTKLSTMGGFLKKKSTTL
                     MLGVDDARVSEAIAIIKKMSGQREQLVYTPPTMAGNCCPTVNMTVPMNMKVGGSTVFV
                     LNVENFQKF"
     gene            69360..70151
                     /locus_tag="ACZPCR_02560"
     CDS             69360..70151
                     /locus_tag="ACZPCR_02560"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HIR1229806.1"
                     /translation="MIKIERVNHSFQDTQVLKDIDLTIHDNEIFGLVGPSGVGKSTLL
                     NCLAGLEKYQSGSISVDGVKLETLNEIQMRQFRRNMGMIFQNFSLIGRKDVFHNIALP
                     MECWKYSKAEIKSRVDELAELTGIQDKLKSRPDELSGGQKQRVAIARALSMNPKYLFC
                     DECTSALDPRSTAAILELLKDLQEKFNITIIVVTHEMSVVQSICSRMAILDGGCVSLT
                     GEVQEIFENKPEQLKRLIGLDDRKISVTMDVEEFAKIKKYLNDIR"
     gene            complement(70123..70224)
                     /locus_tag="ACZPCR_02565"
     CDS             complement(70123..70224)
                     /locus_tag="ACZPCR_02565"
                     /inference="COORDINATES: protein motif:HMM:NF014408.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229807.1"
                     /translation="MFYGGPSAAFFATKDEYKRNMPGRIIGCHSNIS"
BASE COUNT        18976 a        15266 c        20517 g        15466 t
ORIGIN      
        1 gatctgatgc tggttctgga aactcatgga gagcatggaa caggaaaagc agtaaaagag
       61 attgcggacc tggtaggctc agagagagtc agagtggctt atgatacggc caatgtgatc
      121 ttctacggcg gcgtgaatcc ggcagaggag atcgaggact gtatggatgc tgtgtcctat
      181 atccacctga aagataagga tggggaggat aaggagtgga atttcccggc tcccggaaaa
      241 ggaaaagtag atttccctcg gttgtttcaa acacttgaaa aggcgagaaa caacagtccg
      301 ttcagtatcg aaattgaatt tacaccggat ggagcaggaa gcctggaagc agtaaaccag
      361 gcagtgcagg atgcggctga ttacctgaag ggacagggat ttaaacttta agcaggaaaa
      421 gaaacggtct gcgtcagcag attatataaa ttttaagagg aggtatttca acatgagaaa
      481 gaaaatgagg atgacagcac tgatgatgac ggcctttatg gcagcatccc tgacagcctg
      541 cggcagcaag gagactgcag agactgaggc gaaggagagc agcgctgcag aaaagacaga
      601 ggcagcttcc aaggctgagg gagaggcaga gaaaccagca gaggatctga catttggcta
      661 tattgcttat gatatgacag atatctggaa tgagtattct gctaactcat ttgagtatgc
      721 agcaaaggaa gcaggcgtgg aggcagttgt gctggattcc aagaacagct tagaggagtc
      781 tattacagca atggagtctc tgattcagca ggaggtagat ggaatttcta ttttcccgat
      841 ttctaccgag cagggcgctc agcttgttaa gatggccaat gaggctggaa ttcctgtcac
      901 tgtagagaac tttgccatgg atatcgagga tccgggtgac tacattgctt ctgttgcctg
      961 cgagtacgat aagattggtt acgaggccat taagtatatt gcagagcaga agccaggtgc
     1021 aaaggtattc ttctgtgcag gccaggaagg cgccggcgta tacgagaaat atcaggaggg
     1081 cgtagacaag gctgttgagg agctgggaga taagattgaa atcgtggcaa ctctccacgg
     1141 tgactggctg acagacaagg cttacaatgt aacaactgac ttcatttcta caggagaaga
     1201 gttcgattac atttttgcaa acaatggaat gatggcccag ggctgctacc aggcattaaa
     1261 ggatgcaggc atggagaata ttccgattgt atccacagga ggatcaccgg atgactacca
     1321 gatgctgcag gatggaattg aatctgccaa catgacagct cctgtatccg ttcagggtgt
     1381 tcagaccttt aagaacctgt acgattccgt agcagaaggc aagacaccgg agaaatttgt
     1441 ttctcttccg attttaccga ttggtcagga caacttagac gactacattg cctgggatga
     1501 ttatgagaag gcatatgagt ttgtttactc aggagaagag aacgcagaat aagcaggaag
     1561 aacagaaaga aaggggccgg gaactttgaa ggcagattat gcagagaagc ctgtccttaa
     1621 aatgacagga attgagaagg aattttcagg agtttacgct ctgtcaggaa tcacctttga
     1681 tctttacaaa ggagagattc actgtcttgt aggagagaat ggagccggaa aatcgactct
     1741 gatgaaggtg ttaagcggag cttacagtcc gagcaaaggt acaatcagta tcgacggccg
     1801 ggagtacagc tccctgaccc cggccctgtc aagggagctg ggaatcaaca ttgtgtatca
     1861 ggagaatgat ctggttccca gtatgagcgt cgcagaaaat atttatgtag gcaacgaggt
     1921 ttcggatcgg tttggattca taaagtataa ggaactgtat cagaagacga aagaacagat
     1981 ggaagaattt tcgatccatc tggatccatc ggccaagatc gaggatctgt cagtttctga
     2041 tcagcagttt gtgaaaatat taaaggctct ttccgcccag accagggtgc tgatcatgga
     2101 tgagcccaca tccatgttca atgtggaaga cgcagcaaag gtactccgtc tggcagaggc
     2161 cattgccgcc aggggcatca gcattgtgta tatttctcat tcactggagg agatacggcg
     2221 gatcgctgac cgaatcactg tgattcgcga tggagcggtt gtgagaacct atgaaaatga
     2281 aaacagagat atttcactgg ctctgattac ccaggatatg gtaggacggc cggtagatac
     2341 attttttaag aaggataaaa atcccattgg ggatgtctgc ctggaggtaa aggggctgaa
     2401 gctttcaaag gaaagccctg aaatcagttt ttcagtccgt cacggagaaa ttcttggaat
     2461 tgccgggatg gtgggagctg gacggacaga gatcgtccgg gccattacag gggcagatcc
     2521 caaatatgcg ggagagatcc tgatagatgg aacgtctgtg gagatcagga atccggaaga
     2581 cggaatcaag gcaggctttg cacatattac ggaagatcgt caggggctgg gactgatgct
     2641 tcacaacagc gttctggaaa atggcacgat tatcggcctg cgggagaaga ttaaaggctt
     2701 ttttgtcaat ataaaaaagc acccgccgtt aatcgagccg attttcaagg aactccggtt
     2761 aaagacaccc tctgtctgga ctgaggcagt gtatctgtca ggaggaaacc agcagaaggt
     2821 tgttctggca aaatggctgt atgtgcagca ggaaatctac atttttgacg agcccaccag
     2881 aggaattgac gtaaacgcga aagcagagtt ttacaagcag atgtcggccc tgaccaagca
     2941 gggaaagtgc atcatcatga tcagctcgga tatgccggag ctgatttcca tgagtgaccg
     3001 gattctggta gtgaaaaaag gccagattga aggagaactt gtgggagaac agattacaga
     3061 acaggaaatc atcagaagag cattaggggt gaacagaaat gacgccgaag aaacgactta
     3121 ttaaagagca gagagttctg ctggcgattg taattgtagt aattgtagca gctgtatctg
     3181 caattaatcc aaggtttata cagatgaaga acctgattac catttttcag cagatctctg
     3241 tgactggtat tctgacgatg gccatgagta tgcttctgat tggcggagga atcgatcttt
     3301 ctatcggaaa tatcatggta ctgtcaggtg tggtaatggc ttctgtgatc cattctacag
     3361 gaaatacagc cctcgcagtg gcagcaggaa tggcagcggg aacactgtgc ggagctttaa
     3421 acggtgtgat tattgccaag agtaaatgta ttccgctgat tattacgctg ggaactagcg
     3481 agatgtttta tggaatggca ctgactattt caggcggaag aattatgagc tttggcggag
     3541 cttttaacgc catcggaaag acaaaactgt tccagatatt cccggttatg ctgctggtgc
     3601 tggcagctat ggtagtactt tcctacatcc tgatgaaccg gacgaagttc ggacgcagaa
     3661 ttgtagctat cggaggaaat gaaaagaatg cctttctgtc aggtatcaac attgtgagat
     3721 ataaggtaat cctctatgga attgcaggtt tattctgctc tgtggcagct attattttct
     3781 ctgcccgcat cgattccatc acagcaaatg caggagctgg ctatgagaca agcgccctga
     3841 ctgcggcaat tatcggagga gtcacctttg acgggggaaa aggaaccatt tcaggagcct
     3901 ttttaggatg tgtgctgatg ggagttatca gcaatgccat gaatattctt caggtggaaa
     3961 cctacattca gaccattata acaggtgcaa ttattgtatg cgctgtagtt ttaagcaaca
     4021 taaataacat ccgccgcaga taggaagggg aaggtctgct tccggcagcg gtttgcaaag
     4081 gagtgaatag acgtggttaa aatagcagtg ataggggctg gattcatggg aagaacccat
     4141 gcagaggcct acagccggat tgagctggcc caggtggcgg cagtctgcga cagagataaa
     4201 gccctgggag aaaagtttgc cgaggatttt ggatgcagct tttacgaaga ttttgacacc
     4261 atggctgcag aatgtgagtt tgaggtggca gatatctgtc tgcctacgtt tcttcatgaa
     4321 acgtttacag tcagggcagc agaacatgga aaacatattt tctgtgagaa accggcaacc
     4381 ttaagcgtag agtccctgga ccgcatgatt ggagcggcag aaaaagccgg agtaaatctg
     4441 atgattggcc aggtagtccg tttctggcct gaatacagga cggcgaaaca gatgcgtgac
     4501 aatggagagc tgggagagct gaactatgcc tatggagcca gactttctga gcatccggcc
     4561 tggagtgaat ggtacagaag gccggaaaac agcggaggcg gcttattcga tcttcatctt
     4621 cacgacatcg actttttctg ctggatgttt ggggaagtgg agagcgtatt tgcctccgga
     4681 aagaaaaatg agctgggctg ctggaatttt gtcaacagca cactgaactt tcagtctgga
     4741 cagagcgcca gcgttcaggg tgtgattgaa atgacgaagg gttatccatt taccatggag
     4801 ctgcgtctga caggaagcaa ggcaacttat gagtatatca tgaaagcagg ggccaacctg
     4861 gaagatgtag cttcagccag acgtgacaca cgggtttacg gccaggatgg ggcaaggatt
     4921 ctgcctctgg atgagacaga tgcctatgag acagagctgc gtcattttgt agcgtgcatc
     4981 agtgagcaca gagaatcaga gattattccg gctgccagtg cgcggaaggt gatgtgtgtt
     5041 atggaggcat taaagacttc cctggaaaca ggaaaacagg tggctgttga ctatggaaag
     5101 aggcagcctc tggtttaagt aaggagggga taagatgaaa acaggggtga gcatgttctc
     5161 ctttacagag gatgccgatt taaaacatct gtttccacta attaagaaag ccggatatga
     5221 cggggtggag ccggtattca gcgaatacgg atatttgaat gagaaaacct caaaagagga
     5281 cataagggaa atcggaaaga ttgccagaga ggaaggctta gagattccaa gtgtgggagt
     5341 ctggtctctc tggaagtaca atctggtgtc caaccaggag gaaaccagaa gaagagcggt
     5401 ggatattgtg aaaaagcagg tggaagccgc agctctcctg ggggctgaca ccgtccttgt
     5461 ggttcccgga tatgtgggat gtgattttgt ggaggaaccg gagcggatcc gctatgataa
     5521 agcctatgag agatgcctgg aagctttaaa agagctggcg gcttttggag cggatcacaa
     5581 tgtctgcatt ggaattgaaa atgtatggaa tcgttttctc ctgtctcctc tggagatgaa
     5641 gcgtctgctg gatgaggtga attccccctt tgtaggagcg tactttgatg tgggaaatgt
     5701 gatttataca ggatatccag aggactggat tgaaatttta gattcccaca ttaaaaagat
     5761 ccatctgtca gatttccgct atggagcagc tggaatgagc ggctttgtgg atctgttcgc
     5821 cggagacgtg gatttcgtga aggtgggaga gagcctgaaa cgaattggct acgatggatg
     5881 gttgactctg gagatgcttc ccaactataa gcagtttccg gaagtctcac tgctttcaaa
     5941 ccgtccggca gtagaacgga ttgcagcgct tgcacagaaa tagaaaaagg tatacaaaaa
     6001 accgcttctt cgtcacaccc acgaagaagc ggtttttctg atctgaacgg gttaattcag
     6061 acgtttattt tctacgaagc ctgcagtccg gcaattaagc catgctgctt acagccttgg
     6121 ataatctgga aaccttgcgg gaagctgtgt tcttgtggaa aactcccttg gagcaagcct
     6181 tgtcgatctc gcttgtagct actaataaag cagcctgtgc agcagcctta tctccagcag
     6241 cgatagcagc ctcaaccttc tttactacag tcttcacctt ggatctgata gctttgtttc
     6301 ttgcagctct tgtctcagct actaagattc tcttttttgc agatttaatg ttagccaatc
     6361 tgtacacctc catcgatttt cgtaaatatc aataattctc tggtttgcat cagagcctgg
     6421 acacggacag tctaatgtaa acatactctt gtattctagc gaaaatcccc ggttctgtca
     6481 atagtaaaaa tgggaagaat tgagattttt cgcaggtttt tcaggagttt ttttcagaag
     6541 gccggaaatg acagcaaagg gctctgcatc aaaggataaa aatatgctta aaagtctaaa
     6601 ataagaaaaa gtgtaagaaa aacaaagcat caggaggaag cgatggcgca gaatgatttt
     6661 aaccccagaa ccgatctggc ggtggaggag agagagcagt ttacagaagg ggaggagatt
     6721 tcaggagtcg cggtggacga gtgggagggg gagggacgtc ttcggctgac ccgagtggag
     6781 attaaaaacg agcagggggc cagggcgatg ggaaaaccgg ctggcgttta tgtaaccata
     6841 gagtcagaag ccctggcaga gaacgacccg tcctaccatg aggaagctgc ggcagagctt
     6901 gggaggcagc tgcgggagat gattcacaga tgctgtccgg gaaaagagcg cccggccgtg
     6961 ttcgtggcgg gtcttggaaa tatgcaggtg actccagact ccctgggacc aagggtgatt
     7021 gaaaatatgc agatgacgcg tcacctgaat ctggaataca ggaaggattt ctgcagaacc
     7081 catgatcttc ccgtgctgag cggaatcgct ccgggggtaa tggggcagac gggcatggag
     7141 acggcggaga ttgtgaaggg agcggcagag gaaacaaagc cggatttgat tatagcggtg
     7201 gacgctctgg ccgccagaag cgccagacgg ctggcctcca cgattcagct ggctgacact
     7261 ggaattcatc cgggatccgg cgtgggaaac cacaggagag gactgaccag ggaaggtctg
     7321 ggaattccgg tgattgccgt ggggattcct actgtcatag gagctgcggc cattgtccat
     7381 gatacggtga aggccatgat tcaggctctt ttaagggaaa agcagacaga agactatggc
     7441 gcttacatgg aaaaaatcag ctctgaggag cagtatcagc tgatccggga gcttttggag
     7501 ccggagtttg gccctatgtt tgtcactccc caggatatcg acgagagagt gagacggctg
     7561 agcttcactg tctctgaggg aattcaccag gcgctttaca aagaagggac aaacaggtaa
     7621 aaatacggct tggcctgtgg atttctctgc gtgcaggttt tgtgcggaga gaacaaaaaa
     7681 gccgttttcc tgcatagaat gtaaaaggaa acgaaaaagg tgggacatgg atggcaggaa
     7741 attggaagcg caggcggggg ataggaggag aaaagaagaa gctcctggca ggggggcttt
     7801 cagtcattgt gcttgtcctg gctgttttcg gagcgggaaa gacagggctt ccgtctgcgg
     7861 cagccgctca ggaggagagg acggtatctg gcgccaacgc ttatgctgcg ctcagctcct
     7921 gcgcagctct gtggtttccc acatggatcg agtctgttga cggcggggag agggaggcga
     7981 aacaggatgg agcagacggt ctgacgcgct ttctggcaga ccgcctgatg gaaggaatgt
     8041 tctggtacag ggcggcagag aggggagaag acgtaggccg gacaaaaccg gatccagcct
     8101 atgcccatta taaaaagaag caggagcagg caaaggagta cagccgcctg gcagacgccc
     8161 tgtcagccag ccaggtgctc tcagattccg ataaggggag cgtcttagag ccggaaagac
     8221 aaggagccgc atctgcagga agttctgacc tgtctgccgt ttctccttct cctgccatag
     8281 gaactatggc tgggcggaat ctgttagagc gggcagggcg tcctgtgaca ggaaaaacct
     8341 acctggcaga gcagctggcg gactatgatt atgtgatgaa gcatttttac acggttcacc
     8401 ccaccgcggc cgcaggcaga gacatgattc aggcagagac atttctggac agagattttt
     8461 ctctgaaaca ggagacggac agcgaaaagc ctcagatttt gatttaccac agccattccc
     8521 aggaggagtt tgctgattat catacgggaa acagggaagc taccatcgtg ggggcggggg
     8581 aatatctggc tcagcttttg gaggaaaagg gctaccaggt gattcacgat acttccgtgt
     8641 acgatttaag ggatggaaag ctggatcgga acaaggcata ttcctatgcc ctggagggag
     8701 tggagaagat tttgaaggag aatccttcca tcgaggtagt gctggatctc cacagggacg
     8761 gagtggacag caaaacccgc ctggttcagg aggtaaacgg aaagcccacg gctcagatca
     8821 tgttttttaa cggaaccagc cagacgccgg acgggccgat ctcctatctg gaaaatccta
     8881 accgggagga caatctggcg ttcagctttc agatgaagct ctgcgccgac gcgttttacc
     8941 cgggatatgc cagaaatata tatctgaagg gactgcgcta taacctgcac cttcgtccaa
     9001 ggagcgccct ggtggaggca ggagcccaga ccaatacata cgaggaggtg aaaaatgcca
     9061 tggaaccgct ggcagagctg ttagacacag tgctgggaga cggagggtaa atggaaaaat
     9121 actgccgccg gtacatagaa acacctcagt aaacgcaagg aattgttgca gtaacctgga
     9181 aaaaatgata tattggattg catagaaaag gacgccgcca gcttttatgc cggcggcgga
     9241 gatattcctg gaaggattca aagaatcgcc ggaaaaattt agaaatgaca gagaaaagag
     9301 gaaaacaaat ggcaatagtt gaccagagca aagtcagaaa tttctgcatt atcgcccata
     9361 ttgatcacgg caagtcaacc cttgcagaca gaattataga gcagacagga cttctcacca
     9421 gcagggagat gcaggcgcag gtgctcgaca acatggatct ggagcgggag aggggcatta
     9481 ccatcaaatc tcaggctgtc cgcaccgtgt atcgggccaa ggacggggag gagtatattt
     9541 ttaacctgat tgacactcca ggacacgtgg actttaacta tgaggtttcc agaagccttg
     9601 ccgcctgcga cggcgcaatc ctggtggtgg acgcggccca gggaatcgag gcccagacac
     9661 tggccaacgt ctacctagcc ctggatcacg atctggacgt attcccagtt attaataagg
     9721 tagatcttcc aagcgcagat ccggatcggg tggcggctga gatcgaggac gtgatcggcc
     9781 tggaagccca cgacgctccc aggatttccg ccaagacagg cttaaatatt gatcaggtgc
     9841 tggagcagat cgtggagaag ataccggcgc ctgccgggga tccggaagcg ccgctgcagg
     9901 ccctgatttt cgattctctc tacgattcct accgaggagt catcgtattc tgccgcatta
     9961 agaacggaac cgtgaaaaag ggaactccta ttaagatgat ggccacagga gccacagctg
    10021 aggtggtgga ggtaggctac ttcggcgcgg gacagttcat tgcctgcgac gagctgtctg
    10081 cgggaatggt aggctacatt accgccagca tcaagaacgt ccgggatacc cgggtaggcg
    10141 atacgatcac aaaccgcgaa aatccctgca gcagccctct tccaggctat aagaaggtaa
    10201 ctcccatggt ttactgcggc atgtatccgg cggacagctc caagtatccg gatcttcggg
    10261 acgctctgga gaagcttcag ttaaacgacg ccgccctgtt ctttgagccg gagacctcgc
    10321 tggccctggg ctttggcttc cgctgcggct ttttgggact tctgcacctg gatatcatcg
    10381 aggaacgtct ggagagagag tacaacctgg atctggtgac caccgcgccg ggcgttatct
    10441 accgggttta taagacaaac ggagagatga ttgagctgac caacccgtcc aatctgccgg
    10501 atccgtcgga gattgagtat atggaggagc ccattgtgac ggctgagatc atggtgacct
    10561 ccgactatgt aggcgcgatc atgcagctgt gccaggagcg ccggggcaat tacctgggca
    10621 tggagtacat tgagggaacg agagccctct taaaatatga actgccgtta aacgagatta
    10681 tctacgattt cttcgacgcc ttaaagtccc gatccagagg ctacgcttcc tttgattatg
    10741 agttaaaggg ctacgagcag tctgagctgg tgaagctgga tattctcgtg aaccgggagg
    10801 aggtggacgc cctttccttc atcgtgttcg ccggctctgc ctacgagaga ggcagaaaga
    10861 tgtgcgagaa gctgaaggag gagatcccga ggcatctgtt cgagattccg attcaggcgg
    10921 ccatcggcgg caaggtaatc gccagagaaa cagtgaaggc catgagaaaa gacgtgctgg
    10981 ccaagtgtta cggcggcgat atttccagaa agagaaagct tctggagaag cagaaggagg
    11041 gtaaaaagcg aatgcgccag attggaaacg tagagattcc gcagaaggcg ttcatgagcg
    11101 ttttaaagct ggatgaagag taggaaaaag gaagacttat cctgcctgga gctttacatt
    11161 cacattccgt tctgcgtccg caagtgcgca tactgcgatt ttctctcctt tccgtctggg
    11221 gaggaggagc gggagcgcta tgtggaacga ctgacagagg agattgagga ggcgggtgct
    11281 gtttccgagg gctatgtggc gactgccata tttttcggag gcggcacccc ctccgtgctt
    11341 acgccgaagc agacggagcg catcttggag gcgatgaaaa aaagctttta tgtggcggag
    11401 gatgcggaga ttaccacaga ggtgaatccg gggacagcgg acagggagaa gcttgcagca
    11461 tggcggcagg cgggaatcaa ccgtttgagc ttcgggctgc agtccacaga aaacagagag
    11521 cttcagtatc tggggcggat tcataccatg gaggactttc tggaaagcta ccgggccgcc
    11581 agagaggcag gatttgaaaa tattaatatt gacctgatgt ctgcactgcc gggacagact
    11641 gtttcttcct gggagaaaac cctcagaacc gtcgtttccc ttcagccgga acatatttcc
    11701 gcctacagcc tgattatcga ggagggaacg ccgttctgcc agctgtttgg tgaagacggg
    11761 gacgcagcgg aggagaaaaa acgccgccag tcccttggca ttcctgaact tccggacgag
    11821 gacgcggagc gcagaatgta ctatgataca gaacggattc tgggagaagc cggataccac
    11881 cggtacgaga tttccaatta tgcgaagccg ggatatgagt gccgccacaa taaaggttac
    11941 tggactggaa ccgagtatct gggcctgggg ctgggagcct cctcctatat caatataaga
    12001 agagaaaagg gagaagccgc gaagataagc gcgtccggaa aagaaagcgg ggacagaagg
    12061 cagctggaac ggcgttccaa tgtgagggat tttaagacgt atctgagcct tacccgggag
    12121 gatttccggg cgggaaggca gatagaggaa agagatcttc ttaccagcca ggcccagatg
    12181 gaggaattca tgtttctggg actgcgcctg acggaaggga tctctgaggc ggaatttctc
    12241 aggcgtttca gctgtgcctt ggaaacggta tatggagacg ttttggaaga actggccaga
    12301 caggagctga tggagaggta cgagagagaa ggcgcggctt tctggcggct gacgaagaga
    12361 ggcattgatg tgagcaactg tgtgctggcg gaattcctga tggagtaagg cgtggaaaac
    12421 gcagctggtc accacacctg tagcttcctc tgccttaaaa caatcagttg ccaccccata
    12481 gcctttgtgc tatcatggta gacagcaaaa gacggggcgt cagggaggaa atgagaatgg
    12541 aaattacgct ggttcagtat ttaattgtat gtcccctggt atttctggca ggactgatgg
    12601 attcgattgc agggggagga ggcctgattt cccttccggc ctttatgata gccggaattc
    12661 cggcccatct gtctctggga agcaacaaga tgtgttcggt catgggaacg gtggtgtcta
    12721 cggccaggtt tgcaaaaaac ggctttatca attttaagac gtctgtctgg tttgcggcgg
    12781 cagcgctgat cggatcgtcc attggatccc acctgattct gatggtcagc gagggtatca
    12841 tagaaaagct gatgctggtg attcttccgg tggtggcagt ctatgtgctc tggaataaaa
    12901 atctggggga cgattccaag gcaggaacta tctcagcggg gcggaagttt gccgtcagcc
    12961 tggcggcggc tttcatcgta gggacctacg acggctttta cgggcctgga acgggaacct
    13021 tcctgattct gattctgacg ggagcggccc gctataccat gaaggaggcg gcgggaacga
    13081 caaaggtgat taacctggcg tccaatgcgg cggcctttgc caccttcctg ttaaacggca
    13141 aggttttgat tcccctgggc tttatctcag gactgttctg cattctggga cattacatcg
    13201 gatccggcct tgtgctgaca aacggaaaga agattgtacg cccggtggtg ctcattgtgc
    13261 tggccattct gtttgtcaag gtgctgatgg gatagctgga agcggagaag acacggcgtt
    13321 taaataagag aatgaaagaa aattgacaac aaacagacaa taaacagaca gaagaaacga
    13381 gcggaggaaa ctgcacatga aatggaagaa atttacgctg acgaccacaa cggcggctgt
    13441 ggatctggtc agcagcatgt ttgatgagat tggaattgag ggaattgaga ttgaggacaa
    13501 cgtgcctctg acggagaaag agaccaaggg catgtttatt gacattctgc cggagcttcc
    13561 gccggatgac ggtacggcga aggtcagctt ctatctggat gatgacgcag acgtggaggg
    13621 catcctcgcc caggtgaaag aggggcttga ggagctgaaa ctgttcgtgg atctgggaac
    13681 ctgtgagatc gaggcctctg aaacagagga caaggactgg atcaataact ggaagcagta
    13741 ttttaagcct tttactgtgg acgatatcct gatcaagcct acctgggaga ccatcccgga
    13801 ggagcataag gacaagcttt taattcagat tgacccggga actgccttcg gcacaggaat
    13861 gcacgagact acccagctgt gcatccgcca gctgagaaag tatgtgacgc ctgagacgaa
    13921 gcttttagac gtgggaacgg gaagcggaat ccttggaatc gccgcgttaa agctgggagc
    13981 cagggaggtc tttggaacgg atctggatga gaacgctatc acagcagtag gagaaaatct
    14041 ggagtccaac gatatcgggg cagaccgctt tacggtggtt cagggcaata tcatcgacga
    14101 caaggcgatc caggatcagg ctggctacga gtgctacgat gtggcggtgg ccaacattct
    14161 ggcggacgtg attattatgc tccagaagga aatcccggtt cacattaaaa agggcggaat
    14221 cttcatcacc tccggcatta tcaatatgaa ggaagaggca gtgagagagg cctttgcagc
    14281 caacgatgcc tttgaggtgg tggaagtgac ctatcagggc gagtgggtgt ctgtgacggc
    14341 aaagcgcgtg aaataagagg ggacagagcg gaacatgtat catttttttg tggagagatc
    14401 ccagattcac ccggaatctg ttaccatcac agggccggat gtgaatcaca taaaaaacgt
    14461 gctgcggatg aagccggggg agcaggtgtt aatcagcaac ggcgaggatc gtgattacct
    14521 gtgccgtctg acagagattt ctgccgacgc agtggaggcg gaaatcctgg aggagagaga
    14581 ggagactacc gagcttccgg cgaagatctg gctgtttcag ggccttccca aaagcgataa
    14641 gatggagctg attatccaga aggccgtgga actgggggcc tatcagatcg ttccggtggc
    14701 caccaagcga gctgtggtga agctggataa gaagaaagag gaggccaaat taaagcgctg
    14761 gaacgctatt tccgagagcg cggccaagca gtccaagcgt ctcattatcc cggagatcgc
    14821 ccctgttatg agctttgacg aggccctggc ctttgtaaag gattttgaca gcagatgtat
    14881 tccctacgag tgcgcgtcag gcatggactc tgtgaggcag tttgtggaac agactggccc
    14941 gggacagaaa atcgcggtct ttatcgggcc ggagggcggc tttgaggaga cagagattga
    15001 gaaagccagg gaggcgggag tagttcccgt aagccttgga aagaggattc tcaggacaga
    15061 gacagcgggg ctggcgcttc tgtccgtgct ggccttccat ctggaaggcg gcctgtagag
    15121 gaaagataaa aaaggatgga taaaatggaa gcatattttg acaattcggc cactaccaga
    15181 gtgtttgact gcgtaaagga cgcggtggta aacgccatga cagtggatta cggcaatgcg
    15241 gcggcccgcc acatgaaggg cgtggaggca gagcggctga ttaaggaggc cagggcggag
    15301 attgccaaat ctctcaaggt acaggaaaaa gagattctgt ttacctccgg cggaacagaa
    15361 tccaacaaca cagccttgat cggagcggct ttcgccaacc agagagcagg aaagcacctg
    15421 atcaccacag gggtggagca cgcctctatc tacaatacca tggaatttct gcgggagcag
    15481 ggctttgaga ttacttacct tccggtagat tcctacggct gcatttccct ggaggagctg
    15541 gcccaggcag tgagagagga cacgatttta gtctccgtca tgtatgtgaa caacgagatt
    15601 ggagccgtgg aaccggtgga ggagatttca aaggtcatta aggcgaaaaa tcctaagacc
    15661 ctgtttcatg tagacgccat tcaggcctac ggaaaatatg tgatccgccc gaagaagcag
    15721 ggaatcgacc ttttgtctgt cagcggccac aagatccacg gccccaaggg cgtgggcttc
    15781 ctctatattg acgagaaggc caaagtgcgc ccgattctct tcggcggcgg ccagcagaag
    15841 ggaatgcgat ccggaacgga gaacgtgcct ggctgcgccg gcctgggagc cgctgtgcgg
    15901 gaggtctaca gggatcacga ggcgaagatt gagaagctgt accagataag agaacggctg
    15961 attgcaggct taaaggagct gcccggcgtc accattaacg gacacgaggg acgggagaat
    16021 gcgccccaga ttgtcagcgc cagcttcgag ggagtgagaa gcgaggtgct tctccacgct
    16081 ctggaggatc ggggcgtcta cgtttcctcc ggatccgcct gctcggtgaa ccacccgggc
    16141 gtcagcggaa ctctgaaggg aatcggcgtg aagaaagagc tgttagactc caccatccgc
    16201 ttcagcttcg gcctgtttaa cgagccggag gaggcggact actgtctgga ggttttaaga
    16261 gagctgctgc ctgtgctccg aagatacaga gctaaataaa ggaagaacac tgagagaaga
    16321 agattagaaa gaggatgaac atgtttcagt catttttgat aaaatatgcc gagatcggct
    16381 taaaaggaaa gaaccggtac gtatttgagg acgcgctgat gaagcacatc cgccggtcct
    16441 taaaggaatt agagggaacc tttgcagtga caaaggagtc aggacgtatt tacgtggagg
    16501 ccaagtcgga gtttgactac gacgaggtgg tggaggctct ccagagagtg ttcggcatcg
    16561 ccgcaatctg ccctgtgatg cgcgtggagg atctgggctt tgaggagctg aaaaaccagg
    16621 tggtttccta catcagggcg gcctacaagg agcagaactt taccttcaag gtaaactgcc
    16681 gccgtgccaa caagcagtat ccggtccact ccgatgagat gaaccgggaa ctgggttcca
    16741 ttattctgga taccttcccg gagacaaagg tggacgtaca caatccacag gtgctgttaa
    16801 acgtggaggt cagaagcaag atcaatattt actccctggt gattccaggc ccgggcggta
    16861 tgcctgtggg aaccaacgga aaggccatgc tccttctctc cggcggaatc gacagcccgg
    16921 tagcaggata catgatttcc aagagaggcg ttatcattga ggctgtgtat ttccacgctc
    16981 cgccttacac cagcgagaga gcgaagcaga aggtcatcga cctggccaag caggtagccc
    17041 gctactccgg ccccattaag cttcatgtag tcaactttac agatattcag ctctacattt
    17101 acgataagtg tcctcacgag gagctgacga ttatcatgcg ccgttacatg atgaagattg
    17161 ccgaggatct ggccaagaag gacgagtgcc tgggcctgat cacaggcgag agcatcggac
    17221 aggtggcttc ccagacggtt cactctctgg cagtgaccaa cgaggtctgc actcttcctg
    17281 ttttccgccc ggtgattggc ttcgataagc aggatattgt agatatttct cagaaaatcg
    17341 gaacatttga gacatcgatt cagccatacg aggactgctg caccattttc gtggccaagc
    17401 atcctgtcac aaagccgaat ctggatttaa tcagacgttc tgagaagaag ctggctgagg
    17461 gaatcgagga aatgattaag acagcagagg agacggcaga agtcatctgg tgctagaact
    17521 gggggagcgc tgcaggcagc tgccttttaa aggagggata gggtatgaag ttctggagag
    17581 aaaaaagaaa gctctgtatt atagctgcat tgactgctct tctgatatcg gcaggtctca
    17641 tatgggcagg ccggagaagt tctgagctgt ctgtttcaac agaagaaatc tgctcgaacc
    17701 taagcagcca gtcctccttt tcttttataa agacgtccct ccataaaacc atcaggggaa
    17761 ccgtggagga ggacaccata aagtttacct atctttctga accaactgag gcgctgcagg
    17821 cggctgcctt tgatccggat acaggagaga cggatcttca gtattccgag tatcacatca
    17881 ggcaggagga cggctggctg ttctgcaggt ataaggatgg cagatgggag gagagcaggc
    17941 cggaggagtt ttcaccggag gatttcctga aacgagtgtc cttctcgatt gacggagtag
    18001 acctggctgt gattgataag tggaattatg tcagaacaga agaactgggg gagcgaaaag
    18061 ccaggctttt taagggaacc tgcccggttg aagaatactt aaaggcaaag acagaattgg
    18121 ccggatataa gtatttcggg gtcagcgacc agtcaggaga cttgggagag atagaggcgg
    18181 agatctggat cgataaagac tcagacgaag tcctgaagct gagatacgat atcactcggg
    18241 ccagaaagca gtaccaggaa ggcatgagga ttgacgtcac cgaggtgact ctcagcgatg
    18301 agattgtccc cttcgccctt ccggaggagc tgtaacataa aagaaagagc agaaagtttc
    18361 cggtgatttc cattggaacg gggaaacttt ctgctctttc tttttaatat tcctactcta
    18421 cgatgtacgg agccagaacg gtgagaatct catctacctg ggtctcggaa tgaatattta
    18481 aatcaatcgg cttggacaga tccaggctga aaatacccat gatagatttg gcgtcgatga
    18541 cgtatcttcc ggataccaga tcaaaatcaa cgtcaaactt ggctaaatcg tttacgaagg
    18601 atttaacttt atcaatagaa ttaagagaaa tgcgaactgt tttcatgaga aacctcctcc
    18661 ggcctgtgcg tgccgttttg ttttatattt ggctttttgg cgttagtatg cgcttacgcc
    18721 gtcctgtttc tatactacaa atttaacgga aaaaagtcaa gtacgagata gggagaaacg
    18781 tgtaaagttt tgtttaaaaa agagtaatac cgccgtacgg caaaatcgcc tgaaagcagg
    18841 cgccggcaag aaggagacag gagaggcgat ggaagagaaa aaaaggatta aaattgctct
    18901 cggggagttt ggaaccggga gcggaagcca ggaactgttt gagaaacttt cagacaaaat
    18961 ggccagggaa gccgctaggg caggagcgaa aattttgtgc cttccggagc tgtctgcctg
    19021 cggctatttt atcagacggg aggaacttct ggctgcggcg ctgactgctg gggaacaggg
    19081 ggaaaagatg gctgcgacgg cgaaaaagta cggaatttcc ctgattttcg gatatccgga
    19141 gcgggacggg gaaacgattt ataattcctg tctggcagtg ggagcggacg gaagctgcat
    19201 ccagaatatc agaaaggtca atctgtggaa aagcgagaaa aagaggtttt cagaagggcg
    19261 ggatttccca gtgtttgaaa cctgcgccgg acggactgcc gctgtgctgt gctatgactt
    19321 ggaatttcct gaaccggcca gaatcgtatc catgaacggg gccagactga tcttctgccc
    19381 tgcggcctgg agttttgcgg cagagcgcag atgggaggtc gatctggctt cagccgctct
    19441 ctgcaatctg gcctttacgg cgggagccaa ttacagggat gaaaactgct gcggaggttc
    19501 ctgcgtgtac ggcccggatg gaagacagag aagcccggag aaagaaattc ccattgagct
    19561 ttccggcgcg ggagaaagcc gcctgctgat ctttgagctg gatctggacg agacagaaaa
    19621 ggagagggga aaagttccct attacgagga ctggaaggga gagctttacg ggaatctcat
    19681 gaaagaggcg tgggagaaga ggaagcagag cggcagttta ttttcaagtg gactttcccc
    19741 ctcctgatat ggtaaaatta cgagaactgc tgaacatgtg tcagcccagg aaaacgaacg
    19801 agaaaaagga aatatagatc atagcttgag agaaaggaaa catgaaaatg agaaaagctg
    19861 cccttcacaa tttaggatgc aaggtaaacg cttacgagac agaggccatg cagcagatgc
    19921 tggaagacgc tggatatgag attgttccat ttaaagaggg agcggacgtg tatgtgatca
    19981 acacctgctc tgtcaccaac gtggctgata aaaaatcccg ccagatgctt caccgggcaa
    20041 agaagatgaa cccatcggca gtggtggtgg ccgcaggctg ctatgtgcag gcggcaggcg
    20101 aggagctttt gaaggacgag gcggtggaca ttgtagtcgg aaacaacaga aagcaggatc
    20161 tggtgtctat tttagaccag tattttgcag agcaccaggg agtggagaac attattgaca
    20221 taggaaagac aggggaatac gagcctcttc acatcagaaa aatctccgat cacaccaggg
    20281 cctttatcaa ggtgcaggac ggctgcaacc agttctgcag ctactgcatt atcccctaca
    20341 ccagaggccg cgtcagaagc aggcagatgg aggacgtggt gagagaggtg gaggagcttg
    20401 ccgcctccgg ctataaggag atcgtcctga cgggaatcca tttaagctcc tacggtgtgg
    20461 attttaagga ggagaacatc ggccttttag atctgattgt gcgcctggat caggttcccg
    20521 gggtggagcg gatccgcctg ggctctctgg aaccccggat catcacagaa gagttcgccg
    20581 gtacactggc tggtcttaag agcttctgcc ctcatttcca cctgtccctg cagagcggat
    20641 gcgacgagac gttaaagagg atgaaccgcc actacaccac agaggattac gcccaccggt
    20701 gtgaaattct caggaaatat tttgaaaatc cggccattac cacagacgtg atcgtgggct
    20761 ttccgcagga gacggaggag gagtttgaga cgaccaggga attcctgcgc cggattcatt
    20821 tctacgagat gcacgttttt aaatattcca ggagagaggg gacaagggcc gctgtcatgg
    20881 aaggccaggt tccggagcag gagaagaaca ggagaagcga tattctcctg gatctggagg
    20941 cggagctgtc tagcgcttac cgccgttcct ttctgggaaa agaggaagag gtgcttttgg
    21001 aggagcgggt gtctgcagaa ggccgcgact atatgatcgg ccatacgaga cagtatgtga
    21061 aggcagtggt tccctaccgg gagggcctta aaaacgtgac ggtcagggga aaacttgaga
    21121 gaatggtgac agacgaaatt ctgtttttgg cagaggaata gagcctgcct gttgtcttaa
    21181 gaaatatttt tcttgccgaa tgggatattt tgggttagaa taaatgagag tagtaaaagg
    21241 acgtgagaga taatcatggg tgatatgaag aatacgcagt tttttaaaac agtacaggat
    21301 gatacaaagc tggaggtgag ccaggttctg gagcaggtat actttgctct gacagagaag
    21361 ggctacaacc cgattaacca gattgtaggg tatattatgt caggagaccc cacctatatc
    21421 accagccaca aaagtgccag aagcctgatt atgaaggtag agcgtgatga aattctggaa
    21481 gagctgatga aaaattatgt ggagacgcgg cttagataaa ggcaggaaaa gcgggaagca
    21541 gaaccggcag ggagtatctc ccgggattct gccccgcttt ggcggtatat tcagctaata
    21601 tacggaaagc cgcacaggaa gagaatgcga aagcggaatc ggacatacag aaacagggag
    21661 ttggcattgc gccagcttgt tttatagtgg gaaaataccc tcagtctgca ggagcacaca
    21721 cggttcctgt aaacggaggg tttatggaga gccagtaaaa tgagaataat gggacttgac
    21781 ttcggttcca gaaccacagg agtggcagtc agcgatccct tggggataac ggcccaggga
    21841 gtagagacaa ttgtccgcaa ggatgagaat aagctgcgcc agacctgtgc cagaatcgag
    21901 gcgctgatca aagagtatga gattgaggaa atcgtgttag gatatcctaa gaacatgaac
    21961 aatacggcag gagagagggc ggagaagaca gaggcattta aggccatgct ggaacgccgg
    22021 acgggaaagc cggtgattct ctgggacgag cgtctgacga ccatagccgc cgagcgggtg
    22081 cttatggaga gcggcgtccg cagggagaac agaaaggcag tggtggacaa gatcgccgcc
    22141 gttttgattc tgcagggata tctggattcg cgaagcgttt agaagataac taaaaaagac
    22201 agacaggaga cagaaaatga acgatatgtt tgataaaata gatgaaatgg aaaataagat
    22261 tacccttcag tctgaggacg gagagccgat tgatttctat gttctcgagg agacgaagtt
    22321 aaacggggaa aatttccttt tagtaacaga ttctaaagag ggggacggcg aatgctacct
    22381 tcttaaggat atatcaaaac cagaggacgc tgaggcagtg tatgaattcg tagaggagga
    22441 cggcgagctt gattacctct cccggatttt taacgagctg atgggcgaca tggggattga
    22501 gatagaataa gacatcggag gtgcgattta tttgaaaaag gacacaaaaa ataataaggt
    22561 aaaaattata ccgcttggag gcctggaaca gatcggaatg aatatgacgg cctttgagta
    22621 cgaagacagt attattgtgg tggactgcgg actggccttc ccaagcgacg atatgctggg
    22681 aattgatctg gtcattccgg acgttaccta tctgaaaaac aatattaaca aggtcaaggg
    22741 atttgtgatt acccatggac atgaggatca catcggcgcc ctcccctacg tgctgaagga
    22801 tgtgcctgcg ccggtgtacg gcacaaagct gaccatcggg ctgattgagc acaagctgaa
    22861 ggagcacaac atgctgcgca ccatcaagag aaaggtggta aagcacggcc agtccattaa
    22921 cctgggctgc ttcagggtgg agtttgtgaa gacgaaccac agtattgtgg acgcttctgc
    22981 cctggcgatt ttcacaccgg caggcatcat tgtccacacc ggcgatttca agatcgacta
    23041 cactcctgta ttcggcgagc cggctgatct gcagcggttt gcagagcttg gaaagaaggg
    23101 cgttctggcc ctgatgtgcg acagcaccaa cgccatccgc cccggcttta ctatgtcgga
    23161 gaggacggta ggaaagacct ttgacgctat tttctcagag catcagaaca accggattat
    23221 cgtggcaacc ttcgcttcca acgtggaccg tgtgcagcag attatcagct ctgcctgcaa
    23281 gtacggcaga aaggtagtga tcgagggccg cagcatggtg aacgtcatcg gaacagccag
    23341 cgagctgggc tatattgaca ttccggaagg cactctgatt gacattgaaa acctgaaaaa
    23401 ctacaggccg gaggatacag tattaattac cacaggaagc cagggcgagt ccatggcggc
    23461 tctctccagg atggcggcca gccttcacag aaaggtgtct attatgccgg gagacgtggt
    23521 gattttaagc tccacgccga ttccgggcaa cgagaaggca gtttccagag taatcaacga
    23581 gctgtccatg aagggagccg aggtgattaa ccaggatacc cacgtttccg gccacgcctg
    23641 tcaggaggag attaagctta tctactctct ggtgcggccg aaatacgcca ttcctgttca
    23701 cggcgagtac cgccacctga tggcccagaa gaagctggca gagtctatgg gaattccaaa
    23761 ggagaacgtg attgtcatgt cctccggaga tgtgatcgag atcggagacg agggctataa
    23821 gacggtagac cacgttcagt ccggcggcat tctggtagac ggactgggca tcggagacgt
    23881 gggcaatatt gtcctcagag accgccagaa cctggctcag aacggtatta ttgtggtggt
    23941 tctcaccctt gaaaaataca gcaaccagct gcttgcaggg ccggatattg tgtccagagg
    24001 cttcgtgtat gtgagagagt ccgaggatct gatggacgag gcccaggcca ttgtggacgc
    24061 agcggttcag gactgcttaa agcgccacgt cagcgactgg ggcaagatta agaacattat
    24121 ccgcgacagc ttaagcgatt tcctgtggaa gagaatgaag agaaatccga tgattcttcc
    24181 gattatcatg gaagtatagc gctggagata aaagacagcg aaggacagac tgcgaggaaa
    24241 tgagatatga gccgtagaac gagggaaatt aaccgggtga caggaggaat tataagtatc
    24301 tccctgaagc tgattctgtt agctcttgtc tgcattctca tgtatgaggg cgtgacaaga
    24361 ggctacagct tcggccatga gatctttgcc cctgcgccca tggcccaggg ggagggagta
    24421 tcgaggcagg ttacagtgga gaagggaatg tcggccatgg agacagggaa actgctaaag
    24481 gcccagggcc tgattcccaa tgagtacgtg tttgccatag aagcctccct ctatgagtac
    24541 gagattcacc cgggaaccta tacctttaac actgctcaga cctccatgga catgcttcag
    24601 atgctggatg acagtccggg agtttccgat gaggagacag aggagaaaga ggagaaagaa
    24661 tgattgtaaa cgagagactg acttcctatc tccattctct ggatcgggga aatggagagc
    24721 ttttagacag gattgaggcg gaggcggtaa gggattttgt cccgattatc agaaaagaga
    24781 cgggagccct cttaaaaacg ctggtggctt taaagcagcc cagggcgatt ctggaggtgg
    24841 gaacggcggt gggctactct gcccttctga tgggccgggc gatgcctgcc ggctgccatc
    24901 tcaccaccat agaaaagtat gagaagcgcc tgccgattgc cagggagaac ttccggagag
    24961 ccggcatgga ggacagaatc accctgttag agggggatgc ggaggagatc ctggcgggcc
    25021 ttacgggaac ctgggatttt atcttcatgg acgcagccaa gggacagtac ctccactggc
    25081 tgcccatgct gcttcggctg atgccggagg ggggagtcct gatttctgac aacgtactgc
    25141 aggacggcga tttgatcgag tcgcggtacg cggtggagcg cagaaaccgt actatccaca
    25201 gcaggatgag ggagtatctc tatgcgctga ctcacatgga ggagctggaa accagcgtgc
    25261 ttcccattgg agacggcgtg acggtcagcg taaagaagtc cgcaggacga cagacggatc
    25321 ctgcagaatc atagaataga ggaagagacg gatgagagaa ctggagcttt taattccagc
    25381 cggaagtctg gacgtgctga aaactgctgt catttacggc gcagacgcag tctacatcgg
    25441 aggcgaggcc ttcggacttc gggcgaaagc gaaaaacttt accaaggaag atatgaagga
    25501 gggaatcgcc tttgcccacg agagaggggt aaaggtctat gtgaccgcca atattttagc
    25561 tcacaatgag gatctgcccg gcgtggagga atattttgag gagatgaagg aggtgcgtcc
    25621 cgacgcactg attatctcag atccgggcgt attcgccatt gccagaaaga ttcttccgga
    25681 tatggagctt catgtgagca cccaggccaa caatacgaac tacgggacct tcctgttctg
    25741 gtacaatcag ggagcgaaac gggtggtgac agccagagag ctgtccttaa aggagattaa
    25801 agagatcagg gacaggattc ccgaggatat ggagattgag agctttatcc acggagccat
    25861 gtgtatttcc tactccggac gctgccttct cagcaactat tttgtgggaa gagacgccaa
    25921 tcagggcgcc tgcacccacc cctgccgctg gaagtattct gtggtggagg agacaagacc
    25981 tggcgaatat atgccggtct atgagaatga gaggggaacc tacattttca attccaagga
    26041 tctgtgcatg attgagcaca ttccggagat gattgaggcc ggaatcgaca gcttcaagat
    26101 cgagggccgg atgaagaccg ctctctatgt ggccacggtg gccagaacct accggaaggc
    26161 cattgacgac tatctggaga gcccggagaa gtacagagcc aatatggagt ggtacaaggc
    26221 ggagattgga aagtgtacct accgtgagtt taccacgggc ttttatttcc acaagccgga
    26281 tgccacaacc cagatttatg acagcaacac ttatgtaaag aattacacct atatcggaac
    26341 agtggagact gtgtttgagg acggaagctt ccagatggag cagaaaaaca agttcacagt
    26401 gggagagacc attgagatca tgaagccgga cggcagaaat ctggccgtca cagtggagga
    26461 gatccgaaat gaagagggag agcagatgga gagcgctccc catccgaaac agattcttag
    26521 ggtgagactg tctgaaacgc caaaggccta tgatatttta agaagaagcg aacagaatga
    26581 agagaaagag gcagagcagt ctgcgtgcta ggcagtctgc agggctcttc gactgaaatg
    26641 ggggatgcga aagggcagaa atgctgattt tgcaccccct tttagctcag caggaaggag
    26701 gaacgacgat gaactggata ttggaggcgg cggcagggct gtgcctgctc tactatggag
    26761 cgcttgtggc gttcacggga ttttcctttt cattttccct gttctggccg ctctgtgccg
    26821 ctgttcttgg tctgtttgca gtgggacgcc gctattatgc gggacacaga gaacagattc
    26881 ctgtctgggc ggccgtagcg gccgtgacgg cggcgggggc ggttctggct gtcctcctga
    26941 cagctgccgc tctcatagga acgggaattc tgacggccac aaagaacagc atggactatg
    27001 tgattgtcct gggtgccaag gtggagggaa gggagcccag ccgcacgctg aagaagcggc
    27061 tggatcaggc catcgagtat gcggagagaa atcccaatac ctttctggtg ctctccggag
    27121 gaaaagggga ggacgaggag atttcggaag cccaggccat gtatgaatat ctgcgtttta
    27181 acggagtgcc ggaaaaccag ctgcttttgg agatgcgatc cacaaacaca gtggaaaata
    27241 tccagtacag cctggaggcc atccgcaaac aggaaaactg gaaggacagc gtgttccggc
    27301 agattttcgg agacgtggcc cagaacgcct actcgccggg agacgatctg gattctatcc
    27361 acattggaat tctgaccagc gattttcatc tgttcagggc caaggccatc gccagaaagc
    27421 agggagtgaa aaatgtgtac ggcatagccg cgcccacaga tatcggcctg gcgccaaacc
    27481 tgtggatccg ggaatgcttt gccatattaa aaaataaatt tatgggaaat atataagtat
    27541 tagaaagccc aagacagaat tcgagaaaga agagggagat tatatgagac aaatcgcaga
    27601 tctggagtcc tacctcctga aggaggagcg gtatgtggag gaactccatt ccaagggata
    27661 tattttggag cataagaaaa caggagcaag gatttttctt ctctccaacg acgatgagaa
    27721 taaggtattc tgcatcggct ttcgcacgcc gccgtcagac agtacgggag ttgctcacat
    27781 tttagagcac agcgtgctgt gcggctctga aaaattcccg gtgaaggatc cctttgtgga
    27841 gctggtgaag ggatccttaa acaccttttt aaacgccatg acctacccgg ataaaacggt
    27901 gtatccggtg gccagctgca atgagaagga tttccagaac ctgatggacg tctacatgga
    27961 cgcggtgctt cacccgaata tctacaagga ggaaaagatt ttccgccagg agggatggca
    28021 ctatgagatg gagtcagagg acagccccgt taccttaaac ggcgtggttt acaatgagat
    28081 gaagggagcg ttttcctctc ccgagagcgt tttggaccgc tataccagaa acgtcctcta
    28141 cccagatacc tgctacagct gtgaatccgg cggcgatccg gctgtgattc cggagctgtc
    28201 ctacgaggat ttcctgaatt tccacaaaac ctattaccat ccgtccaaca gctacatcta
    28261 tctgtacggt gacatggata tggcggagaa gctggactgg ctggatcggg aatatctgtc
    28321 caggtatgac aggctggagg cggattccag aatccgaagc cagaaggcat ttgctgcgcc
    28381 cagggagagg gagattttct accccatcac agagtcggag tcagaggaaa attccaccta
    28441 tctgtctgtc agcagcgtgg tgggcgagcc gttaaacccg atccactatc tggcgttcca
    28501 ggtactggag tacgtgctga ttgacgcgcc gggagcgcct ctcaagacgg agctgctgaa
    28561 tgcaggtatc ggacaggata ttctgggcgg ctatgagaat ggaattctgc agccctattt
    28621 ctctgtgatc gccaaggacg ccaaccggga gcagaaggga gagtttctgg cagtggtgca
    28681 gggaaccctg cgcaggctgg cagatcaggg cctgaacaag aagagccttt tagctgccat
    28741 caattactat gaattccgca gcagggaggc tgacttcgga tccttcccca agggactgat
    28801 gtacggtctt cagtgcctgg acagctggct ttacgaggga gatccgcttc tttatctgga
    28861 gtatgaggag gccttcgctt tcttgaagaa gagcatagag gagggatact ttgaggatct
    28921 gatccggacc tggctgcttg acaatccttc cactgctgta attttagtaa gcccgaagaa
    28981 aaacatgacg gccgaggagg ataaaaagct ggaggagaag ctggccgcct acagagagac
    29041 tctgacgcag gagcagagaa ttgctctggc ccaggctacg aaggaattga aggaatacca
    29101 ggacgcctct tctccaaaag aggatctgga gaagattcct ctgcttcgca gagaggatat
    29161 taatccggag ccggaaaagc tgattttaga ggagcgtgag gaagagggag tcaaggttct
    29221 gtttcacaat atttttacct caggcatcgg ctatgtgaag gtgctgttta acacagacag
    29281 aattccccag gaggatatgg tttacgcagg actgttaaag gccgttctgg gagctgtcag
    29341 cacaaagcat tacagctacg gggagctggc cgacgagatc aatttaaaca gcggcggcgt
    29401 gaacttcagc attgtctcct atccgtctct tgaggatccg gatcagttta caggcatgtt
    29461 tgccggtacg gccagagtgc tctatgaaaa gctggatttt ggattttcca ttctgggaga
    29521 gattcttacc tcctctgtgc tggatgatga gaagaggctt cttgagatta tcaatgaaac
    29581 caagtccaga gcgcagatgc ggttaaattc agccggtcat tctgcagctg tggccagggc
    29641 gacttcctat ttctctcctt cctctgccta cggcgatgtg acaggcggaa ttgccttcta
    29701 tcagttctta gaggatctgg cgaaaaactt tgaggagaga aagaaaaccc tcatagaaaa
    29761 gctgaaagag acggcgaaac gtctgtttac aactgacaat ctggcagtca gctttacggc
    29821 agatgaaaaa ggatacgggg aaatgaagca gagcctgaag cttctgacag gtattcttcc
    29881 tgaaacaggc ggagaacggt atacttttac ctgtgataag gaaaataaga acgagggctt
    29941 tatgacctcc tcccaggtca actatgtggc cagatgcgga agctttgcgg aaagcggcct
    30001 tccctataca ggcgcgctcc ggacgctgaa ggtgatttta ggctacgatt atctgtggtt
    30061 gaacgtcaga gtcaagggag gcgcttacgg cgtgatgaac ggagccggac ggacaggcga
    30121 gggctacttt gtgtcctacc gggatccgaa cctgaaagag acgaaccagg tatttgaaaa
    30181 cgtggtgaaa tacctggagg aattcgacgc agacgagaga gacatgacaa aatatgtcat
    30241 tggaaccatc agcgatctgg acgtgccgct gttagctccc tataagggca gcaaagcgga
    30301 cgcagcctac ttctcccatc tgacagacga gatgattaag aaagagcggg aggagatttt
    30361 aaaggcgacg aaggaggata tccgggcgct ggctcctgtg attcgggaaa ttttaagcac
    30421 gggaagcttc tgcgtcattg gaaacgcaga aaagatccgg gaaaatcagg aactgttcgg
    30481 cgaggtgaag aatttattta attaatcgta caaaggagaa aataatatgg agcagaattt
    30541 taaatcaggc tttgtgacac tgattggacg gccaaatgtg ggaaaatcta ccctgatgaa
    30601 ccatctgatc ggccagaaaa tcgccatcac ctcagacaag ccgcagacca caagaaacag
    30661 gattcagacg gtttatacag acgagagagg acagatcatt ttcctggaca ctcccggtat
    30721 tcacaaggcg aagaacaagc tgggcgaata catggtcagc gtggcggagc acaccttaca
    30781 ggaggtggac gtgattctct ggctggtgga gcctaccacc ttcatcggag caggagagcg
    30841 ccacattgca gagcagctga aaaaggtcaa gacgccggtg cttctggtga tcaataaaat
    30901 cgacaccgtt aaaaataaag aggatattct cacctttatc gcggcttaca aggatatctg
    30961 cagtttctct gagattatcc ctgtgtctgc cttaaaggag ataaatgtgg aggatgtgaa
    31021 ggacagcatc tttaaatatc tgccttacgg tccccagttt tacgacgagg atacggtgac
    31081 agatcagccc atgcgccaga ttgcggcaga gctgatccgg gaaaaggccc tccggatgct
    31141 ggacgacgag attccccatg gaatcgccgt taccatcgag cggatgacgg agcggaaaaa
    31201 cggtatgatt gacatcgagg ccaccattgt ctgcgagcgc gactcccaca aaggaatcat
    31261 tatcggaaag ggcggcagca tgctgaaaaa gatcggcacc tccgccagaa tggagatcgg
    31321 aaacctgatg gacacccagg tgaatctgaa actgtgggtg aaggtgcgca gagagtggag
    31381 agacagtgat ctctacatga aaaattacgg gtataatccc aaggatattt aaaggaaagg
    31441 cagggtgaaa accgtgcggg agctgatttc agccaccgga atggtgctca gcgcatcccc
    31501 ggtgggggat tatgataaac gtctggtgat tctcacaaag gaacggggaa agatcacctg
    31561 ctttgccaga ggggccaagc gggcctccag ccagctcaga gctccctccc gcccgtttgt
    31621 attcggcgta tttaccatga gcgaggggcg ggatgcctac aatctttaca gcgctgaggt
    31681 ggaaaattac tttgaagagc tgtcaaagga tatggagtgc gcctgctacg cctcctactt
    31741 cgctgagttt gccgggtatt atggaaggga aaatgtggat gaatcggaga acatacgcct
    31801 gctctaccag tcctaccgcg ccctcttaaa gcccggcatt cccaataagc tggtgcgccg
    31861 catttttgag cttcggctga tgacgatcga gggcgagtac cgggagcttc cggagcgggc
    31921 agtcagcgat tcagccgcct acgcctggca gttcgtgatt tccaccccca ttgaaaaact
    31981 ctataccttc cttttgacag agccggtgtt tgaggagttt tcccggtgcg tggaagacaa
    32041 taagcgcaga tatgtggatc gggaattccg ctcattggag attcttaagg tggttacata
    32101 aaaggaaaat gatccgcata tggcaatttc ttttcttcca tatattgaaa agaatgcaca
    32161 aaacaggtat actagaacaa tattgcagat atcagggaaa ctggactctg caaacgattc
    32221 aggagggcag atgatgagaa aagccaggct gatacttgcg gcagcggctg caggagctct
    32281 gctgacaggc tgcagcggcg ggaaaagcgc gttttccccg gaacagagct gcgtctatgt
    32341 ctccggagac gggacgctta gaagcgcgct ggtgcttgag tcagaggagg actttgagga
    32401 gtcagagctg aaggagtttt tagagggggc agtcagccgt tttaatgaga aaaggggagg
    32461 agacggggag gaaggccctg taacccttgc gtcctgcaca gcagatcaag gcgttatgac
    32521 ggcagtgttt gagtacaggg atgccgacgc cctggtttcc ttcaggcaga gcgatgaaaa
    32581 tgaggataac agcaacacat tttcgaatat tgaagtaaag agcgcggcag aggccggaac
    32641 agccggatgg ctttccggag agtttataaa ggccgacggt tcccaggctt ccgggctgga
    32701 cgctgccaaa gagaaacggg cggcggccgt gtcggttcag ggaggaggcg tcctggaaac
    32761 agagggagag cttctctatg tgagcgcagg cgcgcagatt cttgacagta cgtctgtgaa
    32821 gctgccggac ggggaaacgt cagttgtcgt gtttaaagaa aaataagcga taagcaggag
    32881 gtttagttat ggaaaagacg atggaaaaaa ttgtagcgtt agcgaagtcc agaggctttg
    32941 tatacccagg ctccgagatt tacggaggcc ttgccaatac atgggattac ggcaatctgg
    33001 gcgttgagct taaaaataac gtaaagaaag cctggtggca gaagtttgta caggaaagcc
    33061 cctacaacgt aggcgtagac tgcgctatct taatgaactc ccagacatgg gtggcgtccg
    33121 gccatttagg cggattctcc gatccgttaa tggactgcaa gtcctgtaag gagagattcc
    33181 gtgcagataa gctgatcgag gactacatgg cggagaacaa tattgagatg gaaggctctg
    33241 tagacggatg gtctcaggag gagatgaaga aatatatcga cgatcacaat atctgctgtc
    33301 caagctgcgg aaagcatgat ttcactgaca tccgccagtt caacctgatg ttcaagacgt
    33361 tccagggcgt aacagaggat gccaagaata cggtatattt aagacctgag acagctcagg
    33421 gtattttcgt gaatttcaag aatgttcaga gaacatccag aaagaagatt ccatttggaa
    33481 tcggccagat tggaaaatcc ttccgtaatg agattacgcc tggaaacttc accttccgta
    33541 ccagagagtt tgagcagatg gagttagagt tcttctgcga gcctggcact gatttagagt
    33601 ggtttgcata ctggaagcag tactgcatcg actggctgca gaatctgggc atcaagccgg
    33661 atgagatgcg tgcccgcgac cactctccgg aggaactgtg cttctacagc aaggccacca
    33721 cagacctgga attcctcttc ccattcggct ggggcgagct ttggggaatt gcagacagaa
    33781 ccgattacga tctgactcag caccagaacg tatccggaca ggatatgact tactttgacg
    33841 acgagaagaa ggagaaatat atcccgtacg taatcgagcc gtcactgggc gctgaccgcg
    33901 tgactctggc attcctctgc tccgcatacg acgaggagga gattggagag ggagacgtga
    33961 gaaccgttct tcatttccat cctgccatcg ctcctgtgaa ggtaggcgtg cttcctctgt
    34021 ccaagaagtt aaacgagggt gcagagaagg tttacgcaga gctttccaag tactataact
    34081 gcgagtttga cgacagagga aatatcggaa agagatacag aagacaggat gagatcggaa
    34141 ctccattctg cgtaacctac gactttgact ctgagacaga cggcgctgtt actgtccgcg
    34201 accgcgatac catggagcag gtgagagtgc cgattacaga gcttaagagc tacctggagg
    34261 acaaattccg cttctaaaaa taagaagggt ttgaagtgtt gtttttgaag atttttcccg
    34321 gtttttacac aagggcggct gcagatttta caaaaaaggt gtaagataga aaaggattca
    34381 ggagagactg aagacgaggc ggccgcagaa atgacagggg aaagctggat ttccgttttc
    34441 tgtcgctgac gatatgaagc ttgaaaaatt gaaagtaaga aatctggaaa tctgaaaaat
    34501 tggaacaaaa taacaggaaa taaaaaccgc tctggctgga catgatcgtc cggccagagc
    34561 ggttttttac atcttcattt taaaacatgg gcaattggaa actgcttatc ttcctccagc
    34621 gcccggagcg ccttgcggaa ctggaacgta aagagaatca ccgtaaaggt tacggctaag
    34681 gtatctgcga taggctccga caggtagacg gctttggtct gatccatagg cagaatccgg
    34741 ggcagcagat agatgagcgg caggaggagc acaaattttc tcacaaccgc aacggagatg
    34801 gacgccttgg cgtttccgat ggaggtaaac gtcatctggc aggccatctg gatgccaaag
    34861 atgaacataa ccgccatgta aatgcgcaga gccatggcag aaaattctac cagctgcggg
    34921 tcagaggtaa agatgctggc aaatcctgtg gggaacagaa tgattcctcc ccacaggagg
    34981 caggaataaa acaggctgct ctttaaaagc aggaagtagg ctttctttac ccggctctta
    35041 ttgccggcgc cgtagttgta gctgataata ggctgggctc cctggcccag gccctggagg
    35101 ggcagcatgg cgaactgcat gacgctggtg agaatggtca tggctcctac tgcgatgtcg
    35161 ccgccgtagt ttaacaggga agagttaaag cagacggaga tgacgctttc gctggactgc
    35221 atgatgaagg tagccagtcc cagggcgatg cagggcagaa ataccttcgg gttcaggcgc
    35281 atatatttgg cccggatacg gagaaacgtt ttttttccca tcaggaagga cagcacccag
    35341 atacaggaga ctgcctgaga cagtacggta gctgcagccg ctccccggac acccattccc
    35401 agaccaaaaa tgaaaattgg atccagcaca atgttcagga ctgctccaat gagaacagac
    35461 agcatgccaa tcttggcaaa gccctgggcg gtaatgaaag cgttcatgcc taaagtgagc
    35521 tggacaaata tcgttcccac agcgtagata ttcatgtagc tgacggcgta gctgattgtg
    35581 ttttcactgg ctccgaaggc catgaggaaa tcacggttcc agatgagaag aacagcagtc
    35641 agcacagctg atacgagaag ctgcaggcaa aaacagtttc ccagtatatt ttccgccgat
    35701 ttctgatcgc cccggcccat ggaaatggag gctctgggag cgccaccggt acttacaagg
    35761 gctgcgaagg cagatacaat cataataatc ggcatacaga ctccgactcc ggtcagagcc
    35821 atggggccgt ctcctggaat atggccgata taaatacggt ctacaatgtt gtagagcatg
    35881 ttgataagct gagcggccac agtggggagg gccaggctgc ggagcagctt tccaacaggc
    35941 tctgttccta gaaaatcctt attttctttc atgtacggtt cactcctttg aatttgaact
    36001 ttgaatcctg gatttgtgtt tagtatgccc gcccttattc tcaagccccg tcagggcgtt
    36061 ttcaaaaatt ctggaattga gggactgaaa gagctggtat tcatcctcgg aaaagccgga
    36121 gaacagctgg gcctgaaagc tcaggcgggc ccgttcaatt tctctgagaa tttcctggga
    36181 cgcctccgtc agatggaggt ggctttttct ccggtcgccc agatcgcgct ctctggtgag
    36241 aaagccccgc tcaatgagac tgtccgcggc ctgggagaca ttgcccttct taaacatgcg
    36301 cagctccaca atgtcgctgg cagtgtctct gccgggattg ttgtgcagaa acgccagaat
    36361 ttcagcctcc atatgggaca ggccatactg aaggcagaca ggcttcagca gcagctcata
    36421 aaatttgaca attctgcgga ttccaaacag caattccgtg cggctgttca tcgaagctcc
    36481 ccctctcttc actgccggct ttccaaggcg gaaagcggca gacatacgta aactcaaaaa
    36541 gttctaaaaa gaactatttt tcctgtcaca tattgtacct cttttagaag agttgtcaag
    36601 agcaaattgg gaaagaagca ggtgacagaa caggggtttt gagatagaat agagggaatg
    36661 gcctagacct gtcagaaaag ggccaaagat acaatgaaaa agattctaaa atgatgtgaa
    36721 agaacgaaag gatgacttga gctatgggac agaatactgg gaatctgctg gaggggccaa
    36781 ttaaggcgct gtacaggaaa tatctgtttc cgtctatcag cgctacactt gtaacctcta
    36841 tttatatttt ggccgacacg atgatgatcg gccggggcgt gggaccggtg ggaatcgccg
    36901 ccctgaatct gcttctgcct gtgttcagcc tgtttttcgg aacgggcatg atgttcggag
    36961 tggggggaag cgttctgttc tctatttcca gaggaaggaa agaggaggcg atgtgccgca
    37021 gatactttac ggcggcgctg tttctggcgc tttctgtggg aattatttac ggagcgggct
    37081 ttctgttctt ttttgatcct gtgacaaaat ttctcgggcg caatgagagc atggacctgt
    37141 ttgtacgcca gtacgggaaa attctgattg caggggcgcc gatctttgtc tgctcctcgt
    37201 ttttccaggc ctttgtccgt aacgacagcg agccgaagag agctatggcc gcggtaatta
    37261 caggcggtgt gtccaatgtg attttagatt acgtgtttat ttttcctctg gatctgggca
    37321 tggcgggagc cgctgcggct acggtgatcg gatccctgat tacggtagtc attctgctga
    37381 cgcactttgt ctccccagcc aacaccctga gacttgccag acgcttcggc ttccgggaaa
    37441 tgagagtggc ggcagtcaac ggggcttcca gctttttagt ggaaatgaca agcggaatcg
    37501 tggtttttct gtttaacagg cagctgttaa gctatgtggg agatttaggc gtggtagtgt
    37561 atggaattgt gtccaacagc gccctgatcg cgtcctccat ttttaatgga atttcccagg
    37621 cggcccagcc tgtgatggcg atgaacttcg gcgccggaaa gcattccagg gtggaggata
    37681 ccaggaggat ggccttaaag acagcggcgg cggccggagt tctgtttacc gccatcggcc
    37741 ttttctgccc tgaaatgtta gtatacgcct ttgtggagcc gacagaggag attatggcca
    37801 tgggagttac ggcagtccgc atttatttcc tgtccttcct ggcggcggga tccaacgttc
    37861 tgttcgccac ctacttccag tctgtgttaa agcccggctt cgccatgacc atctgtatgc
    37921 tgcggggaat cgtgctgaac gccgttttcg tattcctgct ccccatggtc ttcggagtaa
    37981 acggaatctg ggcggctatg acggttacgg agtgcgcgac gcttctgtgc gcgttcctta
    38041 tgctgaaaag gggaagaaaa accgcataaa ttggaaagat ttgcagaaac cccctttact
    38101 agttacaaga ttatgttata atattcacga aagacggcgg gaatgccggg aatatgcccg
    38161 caggccctgt ccgtcgcggt tacagtccgt tttacaatca gcggggattc ccgcaaaaca
    38221 ataggaggaa aacaacttat ggcaaacaag tgggtttatt tgttcagcga aggcgatgca
    38281 accatgagaa acctgttagg cggtaagggt gctaacctgg ctgagatgac aaagttaggc
    38341 cttccggttc cgcagggctt tacaatcact acagaggcct gcacacagta ctacgaggac
    38401 ggaagaaaga tcaacgatga gatcatggct cagatcatgg atcacatctc caagatggag
    38461 gagatcacag gaaagaagtt cggcgacaag gagaacccgc ttctcgtttc cgttcgttcc
    38521 ggtgccagag cttccatgcc aggtatgatg gatacaatct taaacctcgg tttaaacgag
    38581 gaagtagtag aggttcttgc taagaagtcc ggcaatccgc gttgggcttg ggactgctac
    38641 agaagattca tccagatgtt ctccgacgta gttatggaag taggtaagaa gtacttcgag
    38701 gaattaatcg ataagatgaa aactgagaag ggcgttacac aggacgtaga gcttactgct
    38761 gaggacttaa aggagctggc tgaccagttc aaggctgagt acaaagagaa gatcggcgag
    38821 gacttcccaa ctgatccgaa gactcagtta atggaggcta tcaaggccgt attccgttcc
    38881 tgggacaacc cacgtgccaa cgtataccgt cgtgacaacg atatcccata ctcctggggt
    38941 actgctgtaa acgtacagat gatggcattc ggaaacatgg gcgagacttc cggtacaggc
    39001 gttgccttca cacgtgaccc agctacaggc gagaagcacc tgatgggcga gttcttaatg
    39061 aacgctcagg gcgaggacgt agttgcaggc gttcgtacac ctcagaagat cgaccagtta
    39121 aaggaggtta tgccggaggt ttacgagcag ttcgtaggca tctgccatac gcttgagaat
    39181 cactacagag atatgcagga tatggagttt actatcgagg ataagaagct ctatatgctc
    39241 cagacacgta acggtaagag aacagctaag gctgccttaa agattgcctg cgatttagta
    39301 gacgagggca tgatcacaga ggagaaggct gttactatga tcgacccgag aaacctggat
    39361 acactgcttc acccacagtt cgacgctaag gcattaaagg aggctgctcc ggttgctcag
    39421 gcattagctg catctccagg cgctgcatgc ggtaagatcg tcttcacagc agaggacgct
    39481 aaggagtggg cattaaaggg cgagaaggta gttctggttc gtcttgagac atccccagag
    39541 gatatcgagg gtatgaaggc tgctcagggt atcttaacag tccgcggcgg tatgacatcc
    39601 cacgcagcag tagttgcacg tggtatggga acatgctgcg tatccggctg ctccgagatc
    39661 gctatggacg aggctaacaa gaagttcgtt ctggctggca aggagtacca tgagggagac
    39721 tggttatcca tcgacggttc cacaggtaag atctacgacg gcgttatccc gactgtagac
    39781 gcttccatcg ttggcgagtt cggaagaatc atggcttggg ctgacaagta cagaagatta
    39841 aaggtacgta caaacgctga tacaccagct gacgctaaga aggcccgcga gttaggcgct
    39901 gagggcatcg gtctgtgccg tacagagcat atgttcttcg agggcgacag aatcgacgca
    39961 ttccgcgaga tgatctgctc tgatacagta gaggagagag aggcagctct cgagaagatc
    40021 cttccagtac agcagggaga cttcgagaag ttatacgagg ctcttgaggg caacccagtt
    40081 acaatccgtt tcctggatcc gccgttacat gagttcgttc ctacagagga agaggacatc
    40141 aagaagctgg ctgacgctca gggcaagaca gttgagcaga ttaagacaat catcgactcc
    40201 ttacatgagt tcaacccaat gatgggccac cgcggatgcc gtctggcagt gacatatccg
    40261 gagattgcaa agatgcagac aaaggctgtt atccgcgcag cgatcaacgt acagaaggca
    40321 cacgctgact ggaccgttaa gccggagatc atgattccgc ttgtaggcga cgtaaaagag
    40381 ttaaagtacg ttaagaaggc agtagttgag actgcagacg ctgagatcgc agcagcaggc
    40441 gttgatctga agtacgaggt tggtactatg atcgagatcc cgagagcatg cgtaacagct
    40501 gacgagatcg caaaagaggc tgagttcttc tgcttcggta caaacgacct gacacagatg
    40561 acatacggct tctcccgtga cgacgctggc aagttcttaa acgcttacta cgacgctaag
    40621 atcttcgaga acgatccatt cgctaagctg gatcaggacg gcgtaggcaa gctcatggag
    40681 atggctatta agttaggtaa gccggttcgt ccggagctcc acgtaggtat ctgcggcgag
    40741 cacggcggag atccgtcttc cgtagagttc tgccacaaga ttggtctgga ctatgtgtcc
    40801 tgctcaccat tccgtgtgcc gatcgcaaga ctggcagcag cacaggcagc tctgaacaac
    40861 aaataagatg aaataaggtc cagtcctctg caaggcagat gagacttgaa atgaggaaag
    40921 ccccctatgc tttggcatag ggggcttttt ggcgatttcg gaagtcgttt tcagatatcc
    40981 ttttatcctt cacatccaat cgtaatcatg gtaatgtagt cttctgcttt ttcaagagcc
    41041 atttcattta atccctcttc ataggaatac ggagagagct ttaactgtct tgatttggcg
    41101 aagtcatgaa tggtttcata gacctcctcc agcttatccc aggttccaat acagaaagcc
    41161 cggatatagg ttcctgccgg gcggatttca tcctgttctg agctgttttc actgccatag
    41221 gcgaagaagc agtgttcttc ctttcctgat tccaggcaca tacggcttcc aaagctgtca
    41281 aacaggccaa agatgctgcg aaggcggaga gaaaattctg ctgctgtgga gaagtccttt
    41341 tcgtcatacc ggccagagat agggcttgac agcaggatag gctgggcagg gagtgagacc
    41401 agttccacag aaccgtggcg ggctttcatt cccagctcca gtttgtcgga ttttttctgg
    41461 agaaaagctc tggcggccat gagctgttcc atggagtgat cgatgagctg cttctgatgc
    41521 atggcaattt gcgaaaagga agtatgagaa ggatgctcac gataggattt aatagtttca
    41581 agcggcactc ccagctttcc aagcatacga atcagttcca gttcaacgga ctggaaacag
    41641 gtatagtagt gatatccgtt ttctccgatg acagcaggat ggaacaaccc gatttcatgg
    41701 taatagtgaa gggttctctt gttgactccg ttcaggcgtg cgaattcgcc ggaggagtag
    41761 agagattttg gcatatccgg tttgccggat ccttgctcca cattaaaagg tttcatattc
    41821 agattctcct tgactgtaca gctactgtac atattattat agggcagaaa tgacaaggat
    41881 acaatacaag gagaaaaaat atgaaattta ttaatgaaaa acagtttcag aagaaagact
    41941 ggaaacaggt gaaggatatt tattgcgagg catttccaaa gtgtgagaga aagccatttt
    42001 ttatgctgaa gcactcagtg agaacaggaa aggttcagat gctggctgct atggaaggag
    42061 agctgcttct gggatttctg gcagcagttc cctatgagga catggttatg gtggactacc
    42121 tggctgtgtc agataagata agaagcaaag ggacaggaag ccggctgctg caggaactgt
    42181 gcagccggtt tgccgaaaaa aaggtagtgc ttttaattga gcgtcccgat gtgcctgctg
    42241 aaaatataaa tcagcggctg gccagaagaa agttttattt taaaaatcag tttacttctt
    42301 ccggtattta tattaatggg gcaggaggag aaatggaagt attaaatttt ggcggaacgg
    42361 tgtcaggaca ggaatatatg aagcttcaga aatatgctct gggacgcctg ctgtttgcca
    42421 tgtcagggat cgccctggct tctgaataaa agaaaagatt gtcaatcctc tgattcaatg
    42481 ctactattag ctgtacacat aataagaaac aggatgaaac ggaggacact tctttggaaa
    42541 atacaagaaa tcaggatgga atcggagaga aagagctgtt agtggccagc tttggaacca
    42601 gctatcagga tacccgatgc cggacaattg gagcgattga ggaagaactg gaacgagcct
    42661 ttcctggata ttctgtcagg agagggttca ccagccggat gattattaac cgggtaaaaa
    42721 ccagggatca gattatcatt gacagtctgg aggaggctct gaaacgggcg gcagacaata
    42781 aagtaaggca tctgattgtt cagcctaccc acatgatgga tgggtttgag tatacggctc
    42841 ttgtaaacaa ggtgggggag tattcccatc aatttgaacg gacagcagtt ggaaaaccgc
    42901 ttctttcttc agaggaggat ttccaggcag tgattcaggc gctcacagag gagacagagg
    42961 agtacgatga cggggagact gccttctgct ttatgggaca cggcacagag gcccaggcca
    43021 accaggtata cagaaagctg caggagatgt ttctggcagc aggacaggag aattatttta
    43081 taggaactgt ggaggcggag ccggcgctgg aagaggtgtt agctcaggtg aagaaaggtt
    43141 cctataaaag ggcggttctt cagcctttaa tgattgtggc aggtgaccat gccaataacg
    43201 atatggcagg cgaggaagaa ggatcctgga aacaggcctt tgaggaggcg ggatatgagg
    43261 tatcctgcat tctcagaggg ctgggagagc tggaaaaaat ccggcagctc tttgtaaagc
    43321 acgcaaaaga ggcagaatcc tgtcttttgg cagtctgaca gagcagaaca gagccgcagt
    43381 ttccacgaac atgaataccg ccccctggtt atggcaatta taaagccata gggaattgct
    43441 ccctgaatac ctaaaaccag gaggaagctt tatggaatca attttaaaga atacggagac
    43501 agccaaaaac ctgatgagag cttttgcagg ggaaagccag gccagaaacc gctatacttt
    43561 tgcggcggca gcggcgaaaa aggagggact ccctgttatt gaagcagtgt ttcagtttac
    43621 ggcggctcag gaacaggagc acgcagaggt attttaccgc tttttaaagg aaatgacagg
    43681 ggagagcatt cagatagacg ctggatatcc ggtggacggc tgggataaaa ccctggatct
    43741 tctgaaggcg gcgcggcaca atgaatttga ggagtacagg gatgtgtacc agaattttgg
    43801 aaacattgcc ctggacgagg gatttgacag gattggccag atcttccaca tgattgcgga
    43861 ggtggagaag acgcacggcg accggttcga cctgcttgcg ggactgctgg agaagagcca
    43921 gctgttcgcc tcggaggtgg aaacgggatg ggtgtgctta aactgcggct atgtatacca
    43981 cggaaccttt gcgcccaaat attgtcctgt ctgcgagcat gaacagggct ggtttatccg
    44041 tatggagctg gcgccctatg caggggccta taagcgatta aaaaaataag ccggatacag
    44101 gccggacgcg ggcgggaaac cgtgaagaag aaatcatgaa gaagacaaca tgaaaaagaa
    44161 accgtgaaga agaaatcgtg aaaaagaaac cagaaggaag caatgaaaaa agaggaagcg
    44221 ctatgacagg actgggatgg gccctttttg gcctgacagg attaggggca ggctttttgg
    44281 cccgttccga gtatgagaag aaacattttg tgacagaaac ctttgaactg acgtcagaaa
    44341 agctgagaga ggaggagaga aactttgtgt ttctctctga tctacataat aaccagtttg
    44401 gaaagaatca ggaaaagctt ttaagagcca ttgagaaggt aaggccggac gcggtgctga
    44461 taggcggcga tatgatggtg tgcaaacggg gaaagctgga tctggaaccg tctcttgatc
    44521 tggtgcggac gttagctggg aagtatcctg ttttttatgc caatggaaat catgaggaga
    44581 ggatgaaacg ggaaagagag gtgtatggag acagctgcca gacgttttgc caggaacttg
    44641 agaaggcagg tgtgatgtat ctttcggatg aatcggcgga atttggagat gatatcagga
    44701 ttacgggctg caatatgcag gaaaggtact accgccaccg ctttaccgtc ccccggatgg
    44761 aggaagggga gctggagagc catgtgggaa ggggagaatc gggacggtat cagattctcc
    44821 tcctccactc ccccctgttt tttgaagagt gccgccgctg gggagcggat ttgacgctct
    44881 gcggccattt tcacggcgga accatccgcc tgccctttct gggcggagtg atgacgcctc
    44941 agttccagtt tttccttcca tggtgtgccg gccggtttga cagagaagga aaaaccatga
    45001 tcgtcagccg cggactggga acccattcca ttaatatcag gttttgcaat aagcctcagc
    45061 tggtgcacat ccgtctgagg aaaaagcagg gctgacggct ggaaatcagt ccatgcagcc
    45121 ggagcagaac gcgctgcagc cggacggggt aacggcgcag ccgcccatgg ccgtttccct
    45181 cagctcctgg ggaagccgtc tgcccactgc gtacatggcg tccagcattt catcgaaggg
    45241 aatcagctgg cggactccgc tcagggcaat ctcagcggcg gtcagggcgt tggctgcgcc
    45301 ggcggcgttt ctgccttggc agggacattc caccaggccg ccgatgggat cgcagacaag
    45361 tcccagcgta ttcatgagaa cggtggaggc tgcgtcgaga cactggacag gcgaaccgcc
    45421 catcagctcc acagcggcag aggccgccat ggcggaagct actcccactt cagcctggca
    45481 tccgcccaca gcgcccgcca ctgtggcgtt tctcatagcc agatagccga tggctccggc
    45541 gttaaagaga gcgtccagaa tctggctgtc ggagaaatga tattcttcct gaagagccag
    45601 aagaagcccc ggcacaatgc ccgaggatcc ggcggtgggg gccgccacaa tcagccccat
    45661 agaggagttt acctccagga cagccatgga gaaggcgatg gcccggctga gtacagagcc
    45721 ggccgcgctt ttgccggcca gcctccgctc atttaccagc ctggcttccc ctccgatgag
    45781 accgcccata gactttttcg gagcagttaa gggggagtgg gccgattcct tcataatttc
    45841 caatgcccgc agcatgcgcg cctcgactgc ctcctgggaa gtttcaccca gctcgcattc
    45901 cctctgcttc atcacctggg aaataggcag gccgcagctt tcgcacagct ccagcagttc
    45961 gtttccattt ttaaaatcca tatctgcagt ctcctcctta cagctcaatc agcataacgt
    46021 ctttcacatt gggatttttc cggatctcgt ctgggatgcc ctccggcaga gagccgtcga
    46081 attctacaat gctgtaggcg gtgcttccct tggcctcacg aaacagcttc aaaaaggcaa
    46141 tgtttacgtt ggctttgctg aggcaccccg taatgtgggc gataacgccc tgcctgtcct
    46201 tctgaatcac gatcagcgtg ttgtactcgc cggaaaaatc cacctccgcc tgattgatgc
    46261 gggtaattcg gatttttccg ccgcccagag actctccccg gaccgtcatc cggcggccgg
    46321 aggatccggt catggcgata tccaccgtgt tgggatggac ctccgtttcg atttcattgg
    46381 gagtgaagga aaattcgatt ccgcgttccc tggcgataga aaaggagtcg ggaatccgct
    46441 tgtcgtctgt ggaaaacccc ataatgccgc ctaaaagggc gcggtctgtg ccgtgtcccc
    46501 ggtaagtttt ggcaaaggat ccgtacagag tgaagtctgc cttcaaaacg gggcagccaa
    46561 acatctttct ggccatgagg gcaatggaag cggctccggc cgtatgggag ctggaagggc
    46621 cgatcatgtt cggccccagc acatcaaaaa cactgataaa tgtcatagat aatctgttcc
    46681 tccagaatga tttgcgttta ttataccaca ttcactaagc tcgaaaagac ctcgctaagt
    46741 gtctgggtat gactcgtact aacctcatac ttcgcctgtg gctcgtactc gctaagtact
    46801 catattatac cacaaacagg tgaaagaacg gaagaaaaga aatttttcgt taagttcctg
    46861 ccggtttact ttactgtcca aatctgctat acttggattc catgggctgt gcagaaggac
    46921 gtgcagaccg gagtaagaga aggatggtgc gtatgggaat ttcctataag ctggagcatt
    46981 tcgaggggcc tcttgatctg cttctgcatc tgatagagaa gaataaggta agcatctatg
    47041 atattccgat tgtcacaatc acagagcagt atctggacta tgtgaatcac atggatatcc
    47101 aggatctgga tctggtcagt gaatttctgg tgatggcggc cacgctgctt gatattaagg
    47161 ccagaatgct ccttcccagg gaggagaagg aggaagaaga ggaggaggat ccgagagcag
    47221 agctggtccg ccgccttctg gaatacaaga tgtataaatt tatggccaga gagctggaag
    47281 atatggagga ggacgcggag cgcctccttt ttaaagcgcc tacgattccc agggaggtgg
    47341 cggagtacga ggcgcctgtg gatctggatg agcttttaaa ggggctgacg ctggcgaagc
    47401 tccaggagat ctttgagtct gtgatcaggc gtggggagaa taaaaaggat cctgtccgca
    47461 gcggttttgg aaccattgcc agggagccgg tcagtctgaa aaagaggctg gcctttgtcc
    47521 ttggctttgc cagaagaaac aggaagttca gctttcgtga gatgttaggg ggaacggccg
    47581 ggaaaatgga gacggtcgtc acctttttag cggtgctgga gctgatgaag gtcggaaaga
    47641 tttatctgac ccaggagacc gtggacagcg atatgtacat agaatccctg gagccggagg
    47701 gaacgtatga ggaaatcgat tttgacgtgc ctggcacggc agaataagcc ggaaggcgca
    47761 ggctgacaaa gaatatttcg ggcggaacag aaaatagcgg gagaatcagg aatgagagaa
    47821 aaggacaggc ttttaaggca ggaggcggct gcggaggcag tgctctttac gatggggaga
    47881 gccgtggagc ttcgggagct ttcggcggct cttgagacag gcgaggagga agcccaggcg
    47941 gcggtggaac ggctgcggga aaaatacagg gaagagggca gaggcctctc cattatcgag
    48001 ctttccggaa gcttccagat gtgtacgaag gcagaatact atgaaaattt aatccgggtg
    48061 gccaaggcgc cgaaaaagca ggcgctttcc gacgtggtgc tggagacact ttcgattatt
    48121 gcatacaaac agccgattac taagatagag atcgagcaga tacgaggcgt aaaatcagat
    48181 cacgcggtca accggctcat cgagtataat ctggtgtatg aagtgggacg gctggacgcg
    48241 ccggggcggc cggctctgtt cgccacgaca gaggagtttc tgcgccgttt cggagtgggc
    48301 agcatggagg agcttcctgt cattgatccg gagcagctgg acgagtttaa gctggaggtg
    48361 gaggaagagc ttcagatgaa cgacgaggag ctgcaggctg ttttggaggc cgccgcgtca
    48421 gctgaaagcg ggacggagaa aagcccggag ggaaaggctg gggagacagc aaaggagaag
    48481 cccggagaga aggcggaagg acagaccggc ggacaggcaa aggagccgta aaaaatttcc
    48541 gtgggccgcg gtccgcatag gctggggctt tgcggcttgt caagaacttt ttgatggaaa
    48601 atggctattg acttccatgg gggcagatga tacgatatgg ttcaggcatg acacagtatc
    48661 ttgtgccgag tgttaaaaat aagactaaat atagtctttt gtatacaata tcttgtgtct
    48721 gcggcaggaa gcgtcagaca gaggcgggag agggttcgga ctgttccgcc gttcaaaaag
    48781 tcagggagga gatcagagga tgaagtgtgc tgagataaaa gtaatcaaaa aagacggaac
    48841 ccgggaagat tttaacgtgc agaaggtggt tgtggcggta aacaagtcgg cagagagagc
    48901 catgattcag ttttcacagg cagagctgaa ttttatctgc cagtttgtgg aggagaaggc
    48961 ccaggagctg ggcgtggcgg agatccccat tgccaggatg cacaacctgg tggagggagc
    49021 gttagagagg gtgaatccgc tggttgccaa gagctaccgg gattaccgca actacaagca
    49081 ggatttcgtc cagatgttag acgaggttta taaaaagagc cagtctatta tgtacattgg
    49141 agacaaggaa aactccaaca cggacagcgc tctggtttcc accaagcgaa gcctgatttt
    49201 caacgagtta aacaaggaac tttacaagaa gttcttcatg acagtggaag agctgcaggc
    49261 ctgccgcgac ggatatctgt atattcatga catgtccgcc cgccgggaca ccatgaactg
    49321 ctgcctcttc gacgtgaaga cggttctgac cggcggcttt gagatgggca atctctggta
    49381 caacgagccg aagactctgg acgtagcctt cgacgtaatc ggagacattg tgctgagtgc
    49441 ggccagccag cagtacggcg gctttacggt tcccagcgtg gaggagattc tggctcccta
    49501 cgcggagaaa tcctatgcga aatacattga aaagtacgaa ggactgggcc tcagccggga
    49561 gaaggcggag gaggtagcct gggcggatat ccagagagat atggagcagg gcttccaggg
    49621 ctgggagtac aagtttaact ccgtttcctc cagccgggga gattatccgt ttatcaccat
    49681 gacggccgga acaggaaaaa gccgcttcgc caagatggct accatcacca tgctggacgt
    49741 gcgcagaaag ggacagggaa aggacggcca taagaagcca gtgctgttcc cgaagctggt
    49801 gttcctgtat gacgagaatt tacacggccc tggaaaggag ctggaggacg tatttgaggc
    49861 gggaatccgc tgctcctcca agactatgta cccagactgg ctgtctctga ccggcgaggg
    49921 ctacattgcc agcatgtaca agaaatatgg caggattatc tctcctatgg gctgcagggc
    49981 cttcctctcc ccatggtatg agaagggcgg catggagccg gcggacgaga cggacgtacc
    50041 gcgctttgtg ggacggttta acgtaggcgt tgtgagcctt cacctgccta tgattttagc
    50101 caaggccaga caggagagcc gcgatttcta tgaggttctg gactactatc tggagctgat
    50161 cagaaaaatc cacatccgca cctacgctta tctgggcgag atgagagctt ctaccaatcc
    50221 gttagcttac tgcgagggcg gcttctacgg cggccacctg ggcctgcatg acaagattaa
    50281 gccgcttctc aagacagcga ccgcatcctt tggaatcact gccttcaacg agctgcagga
    50341 gctctacaac ggcaagtccc tggtggagga tggccagttc gctctggagg tgctggagca
    50401 catcaacgag aaggtgaacc agttcaagaa ggaggacgga aatctctacg ccatttacgc
    50461 gactccggcg gagaacctgt gcggtcttca ggtgaagcag ttcagaaaga aatacggcat
    50521 tattgagaac gtctcagaca gggaatatgt gagcaacgga ttccactgcc acgtgacgga
    50581 ggacatcacg ccgatccaga agcaggatct ggagtaccgc ttctgggagc tgtcaaacgg
    50641 cggcaagatc cagtatgtga agtatccgat tgcctacaat acagacgcca tccgcacgct
    50701 ggtgcgccgg gccatgaaga tgggctttta cgagggcgtg aacctgtctc tgtcctactg
    50761 cgacgactgc ggccacgagg agctgaacat ggacgtatgc cccaagtgcg gcagcaggaa
    50821 cctgacgaag attgacagaa tgaacgggta tttaagctac tcccgcgtaa agggagacac
    50881 ccggttaaac gacgcgaaga tggcggagat cgccgagcgc aaatccatgt aaaatccggc
    50941 cgcgcaggct gaggaaaggg agagaggacg gaacgatgcg ttatcacaat ataacgaagg
    51001 acgatatgtt aaacggtgac ggactccgga cagtattatg ggtggcaggc tgctgccacg
    51061 gctgcaaggg ctgtcagaat cccgttacct gggatataga aggaggcctt ccctttgatg
    51121 gggaagccag ggcagagctg tttgcagagc ttgaaaagcc ctatatttcc ggcgtgacct
    51181 taagcggcgg agatcccctc catccggcca accgggagga gacaggggct ctgatgaagg
    51241 agatgaagga acggtttccc gataagacga tctggcttta cacagggtac gactgggatc
    51301 aggtgaagga tcttccctac attggttttg ccgacgtgct ggtagacgga cggtttgtgg
    51361 aggaactgaa ggacgaggac gccttctggc ggggcagcac caaccagaga gtcatcgacg
    51421 taaagaaatc cctggagagc ggaaacgtaa cgcttcactg cagatagcgt ccgcactata
    51481 aaacgaatag acagaatgca gcctttgggc ggccggccgt ttcagacggc gcggccgccc
    51541 ttttcgcaca taaaaaagtg aaatctcgtg acattcttcc tgcgaaatga taaaatagca
    51601 gagacattta tgagtacagg aagatgaaag agaggaatca ggacagaatg aagatcagaa
    51661 ttaaatattt tacagataaa atagacaggc tctgctatat agatggaaaa tcagactgga
    51721 tggatctgcg ggctgccagg gatgtggagc tgaaggcggg agagtttgcc ctgatcccac
    51781 tgggcgtggc catggagctt ccgaaaggct atgaggccca tgtggttccc agaagcagta
    51841 cctttaaaaa cttcggcgtg attcagacaa accacatggg agtgattgac gagacgtact
    51901 gcggagataa tgatcaatgg ttctttcctg cttacgcgtt aagagatacg gtgatccatg
    51961 taaacgacag aatctgccag ttccgcatta tggagcacca gccgtccttc tccttcgagg
    52021 agacagactg ccttggaaat caggacagag gcggccatgg aagcacaggg acaaagtaga
    52081 gaaagcggca taaacgccga accatgctct gaaagagcgc cagagtctgt aaaggcagaa
    52141 aggaggcctg gatgaaacga cacagactgc tttgccgggt gctggccgca tcagcggcgg
    52201 cccttttgct gactggctgc ggggactcga aaaaagcccg ggaagccaga atgaccggca
    52261 ttgaacagat gaatcaggaa aactatgagg acgccatcgc ctcctttgat aaagctctgg
    52321 acgaggcgga tggaattgta ggcccgtttg agctggacgt gctgaaatac agggccgagg
    52381 cagagtatct gacggaggat taccgggcgg cagctcatac ctatgatatt ctggcggatg
    52441 tagacgggga aaaacgggaa tatttgtatt atggagctgc gtcccacgcc ctggccggag
    52501 agctgggcga ggcggtggag gcttacgaaa aagcccagaa aggggcgtct ggagagaaga
    52561 aacaggatca gaaagctcag aaaccggcag acgggaagaa agagaatcag aaacaggaag
    52621 accaaaaggg tgcagatgga acgcagcagg aaaccgcgtc cggccaggct gccttggatc
    52681 cggatcagaa gtccattcat gaggccgccc tttccccgga ggaggaggca ggccgctctc
    52741 tggccctgtc ggccatcgga aaggcctacg aggatcaggg acagtatgag gaagccatga
    52801 gcttttacga gggagcggcc agctccggtc tgacggcgga tctgtgcaac cggatgggcc
    52861 tgtgcatgat ggcggcagaa cagtacgacg aggctctttc ttattttgag aaggggatga
    52921 ctctgcagga cgaagtgaaa atgccggatt taaagtacaa cgaggcggct gcctacgaat
    52981 acaaaggcaa tttcgagaag gccctggagc ttttaaacgc ttatgtatcg gcttacggct
    53041 ctacgcctga gatagagagg gaaatcgtct ttctggagag ccggtaaaaa gaaatcagga
    53101 aaaggagtgt gaacatggcg gagctttatg atatgcgcga ggaagaggaa cgggtgattc
    53161 ttgtggccgt cagtacaggc gacggggacg atacggagga gtcggtggac gagctggcag
    53221 agcttgtgaa gacagcggga gccgtggcgg cagaccggat tatccagaat cgtgaacggg
    53281 tgcatccggg aacctacctg ggaaagggaa aaatagagga ggtcagagag agggttctgg
    53341 ctctgcaggc tacaggcgtt gtctgtgatg acgaactgag tcccgcccag cttcgaaatc
    53401 tggaggacgc tcttcagacg aaggtcatgg acaggaccat ggtgattctc gatatttttg
    53461 cctcccatgc agtgaccaga gagggaaaaa tccaggtgga gctggctcag ctgcgctacc
    53521 gggccgccag gctggtcggc ctcaggaatt ctctttcacg tctgggagga ggaatcggaa
    53581 cgagaggacc aggagagaag aagctggagt ctgacaggcg tctgatccat gagagaatcg
    53641 ggcagctgaa ggcagaactg gaggacgtaa aacgccacag ggaggtggcc agacagcaga
    53701 gagacagaga ctgcaccgtg tcggcggcca ttgtgggcta caccaacgca ggcaagtcca
    53761 cgctgctcaa ttatctgacc gacgcaggga ttctggcgga ggacaagctg ttcgccactc
    53821 tggatcccac caccaggatg cttaagcttc ccagcggcca gaatattctt ctgacagata
    53881 cggtaggctt tatcagaaag ctgcctcaca acctgatcga ggcctttaag agcactctgg
    53941 aggaggcacg ctacagcgac atcatcctcc acgtggcgga cgtgtccaat ccacagctgg
    54001 acacgcagat ccatatcgtg tacgagacgc tgcgccagct ggaaatcagg gataaaacca
    54061 ttgtcactgt attcaacaag atggataagc tgacagggga tgtgatttta agggatttca
    54121 gctctgactt tcaggtgaaa atttccgcta agacagggga gggaatcccg gatctgttag
    54181 agacgctgga aggaatctta agaagccgca gagtgtatct gaacaaggta ttttcttatg
    54241 gggaggccgg gaagatccag tccatcagaa agtacggaga gcttctgaag gaggagtata
    54301 cagaggcagg aatccaggtg gaggcatacg ttccggcgga gatctacgga agcctgatgt
    54361 agtggaaaat tgtgaaaaaa acaacgacaa agcacaatat ctggttttta ttaaaaacac
    54421 aagtatagat attgtgcttt tttgcgccct ttgctataat ggagtctgta cccgcccagc
    54481 ggggttctgg aaaggagaag gcagtatgat tagtgtgatt aagcgtgata aagagacagt
    54541 cggttttcag ctgacaaagc tgacagcttc catagaaaag gctctgcagg cagcaggaaa
    54601 cgtgtgcagc caggagatag cagagctttt atcgctccgg acgacggcgg atttccagcc
    54661 gaagatctgc gagggagagc tgagaacgga ggagatcaag gccagcgcgg cccgcgtact
    54721 ggagcaggca ggctatacag aggcggccag agcatacctt tcatataaaa aagagaagaa
    54781 cagcgcagag gaaaagaaga atacgctgtt agattataag gacgtagtaa acagctacgt
    54841 gaaggtggag gactggagag taaaggagaa ttctaccgtc acctactctg taggcggcct
    54901 gattctcagc aattccggcg cggtgacggc caattactgg ctgtctgaga tctatgattc
    54961 cgagattgcg gaggcccacc ggaatgcgga catccacctt cacgacctgt ccatgctgac
    55021 gggatactgc gcggggtggt ccttaaagca gctgctgtta gaggggctgg gaggcattac
    55081 gggaaagatt acctcctccc cggccagaca cctttccgta ctctgcaacc agatggtaaa
    55141 tttcctgggc atcatgcaga acgagtgggc gggagcgcag gccttttcct cctttgacac
    55201 ctatctggcc ccctttgtca aggcagatca tctgtcctac gacgcggtga aaaagtgcat
    55261 tgaatccttt atctacggcg tcaacacgcc gagccgctgg ggaacccagg ctcccttctc
    55321 caacattacc ctggactgga cggttccgga cgacatggct gagatgaacg ccattgtagg
    55381 cggaaaggag atggatttca agtacaagga ctgcaaagag gagatggatc tcatcaacag
    55441 ggcctttatt gagactatga tcgagggaga cgccaacgga agaggcttcc agtacccgat
    55501 tcctacctat tctattacaa aggattttga ctggtccgat acggagaata accggctgct
    55561 gtttgagatg acctccaaat acggcacgcc ctatttctcc aattacataa acagtgatat
    55621 gcagcccagc gacgtccgca gcatgtgctg ccgtctgagg ctggatctgc gggaactgcg
    55681 cagaaagaca ggcggattct tcggatccgg ggagagcacg ggatccgtag gtgtagtgac
    55741 catcaatatg ccgagaatcg cgtacctggc ctccgatgag aaggatttct ttgcgcgcct
    55801 ggatcacatg atggatgtgt cggcccgctc cttaaagatt aagagaactg tgattacaaa
    55861 gcttctggac aacggtctct acccctacac caagcggtat ctgggaacct ttgagaacca
    55921 tttttccacc atcggtctgg taggcatgaa cgaggccggc ttaaacgccc gctggctcag
    55981 gatggatatg actcacaggg agacgcagga atttacgaag aaggtattaa accacatgag
    56041 agagcggctg tccgattacc aggaactgta cggagacctc tacaacctgg aggccacccc
    56101 ggcagagtcc acctcctacc gcctggccaa gcacgacaga aagcgttatc ctgacattat
    56161 tacggcggga gagccggggg agacgcctta ctacaccaac agctcccatc ttccggtggg
    56221 gtacacggag gatattttcg acgctctcga tattcaggac gagctgcaga cgctctacac
    56281 gtctggaacc gtattccacg ccttcctggg cgagaagctg cctgactggc aggctgcggc
    56341 ccggctggtg agaaccattg cggaaaatta caagctgccc tattacacct tatcgcctac
    56401 gtactccatc tgcagggagc acggctacct ggcgggagag cattttacct gcccgatctg
    56461 cggaaagaag gcagaggttt acagccgcat taccggctac taccgcccag tgcagaactg
    56521 gaacgaggga aagtcccagg agtacaagga cagaaagacc tactgcatgg agaattccag
    56581 attaaaggat ggcagggagc tttctgaggg gctggagaca gagaaaaaga cagtgaagga
    56641 gaacagagag gcgcccagaa aggggatggg ggccaaggca ggggtttatc tgttcaccac
    56701 taagacctgc cccaactgcc ggattgccaa ggaatgtctg aagggaacag attatacggt
    56761 agtggatgcg gaagagaatc cggatatgtc cagccggttc ggtattatgc aggcgccgac
    56821 ccttgtgctg gtgggaaaag acggggagat taagaagttt gtcaacgcgt ccaacatcag
    56881 gaagtttgcg gaagagtata aataaaagcg ttatttaaaa ttatgatctg tctaaaacgg
    56941 ccggactctg tccggccggt aagtgtattg ggaggaagtt tatgaaaaaa ctggaggaga
    57001 ggtatctgga acggctggcg gagctgtatc ctaccatcgc ggcggcgtct accgaggtga
    57061 ttaatctgga ggcaatttta aatcttccga agggaacgga gcactttttg acggacgtcc
    57121 acggggaata cgaggccttt tcccatgtgc tcaaaaacgg ttccggctct gtcagaagga
    57181 agattgacga cgtgttcggc cacaccctga gccggcagga caaacagacc ctggccacgc
    57241 tgatctatta tccatgggag aagatggagc ggatccttaa aaaggaggag aatccggagg
    57301 actggtataa gattaccctg taccgtctga tcgaggtgtg ccggagagct tccagcaagt
    57361 atacccgctc caaggtgaga aaggctcttc caaaggaatt tgcctatgtc atggaggagc
    57421 tgatcaccga gcgggaggag ctggcggaca aggaatccta ctatggggcc attgtggaaa
    57481 ccattatccg ggtgggacgg gccaagcagt ttatcgcggc catgtgcgag ctgattcaga
    57541 ggctgaccgt cgatcacctg cacatcgtgg gggatatttt cgacaggggg ccgggaccgc
    57601 acattatcat ggacaagctg atgacctacc actcagtgga cattcagtgg ggaaaccacg
    57661 acgtgctgtg gatgggcgcg gcggcaggcc agatctgctg cattgccaat gtgatacgaa
    57721 tctgcgccag atacggaaac ctggatattt tggaggacgg ctacggcatc aacctgctcc
    57781 ccttagccac ctttgccatg aacgtttacg cggaggatcc atgcgcctgc tttgccttaa
    57841 agggaacgaa tacttacgcc cagcaggagc gggagataaa tctgaaaatg cacaaggcta
    57901 tctctgtgat ccagtttaag gcggagggac agatcatcag aaagcatccg gaattcggcc
    57961 tggaaggcag aaatctgctc caccggatcg attacgaaaa gggaaccatt gatctgaatg
    58021 gcacagaata ccagcttctg gacaaaaatt tcccgaccgt ggatccggcg gatccctact
    58081 ctttcacaga ccaggaggcg gagatcatgg aacggctctc caaggccttt atgggctgcg
    58141 agaagcttca gcgtcacatg aagtttctgc tggccaaggg aagcctttat aaggtgtaca
    58201 ataacaacct cctctaccac ggctgcgttc ccctcaatga ggacggaacc ctgaaatcgg
    58261 tggaaatcta cggaaaaaag taccgtggaa gagctctcta cgacgccctt gacaactatg
    58321 tgagaaaggg ctttgtggcg gtggacagag cagagcggga gaagggcagg gatctgatgt
    58381 ggtatatctg gctcagcgag aattctcctc tgtttggaaa ggataagatg gctacctttg
    58441 agcggtattt cctggcggag aaggagactc acaaggaggt aaaaaacccc tactaccgct
    58501 tcctggaaaa cgaggaggtc attgaccgga ttttgcggga gttcggcctg gagtcggagg
    58561 gcgcccacat tatcaacggc catgtgccgg tgaagacgaa ggacggggaa agccccatta
    58621 agtgcggcgg aaagcttctg gtcattgacg gcggcttttc aagagcctac caggaggaga
    58681 cggggattgc cggatatacc ctgatctaca attcctatgg cctcattctg gcagcccata
    58741 agccctttga gtccacagag tccgccattg aaaacgagag cgatatccac tcggagagca
    58801 ccatggtgaa atgggtggcc aagaggaagc gggtgggcga cacagacgca ggcagggagc
    58861 tgcgggagaa gatccgggat ctggaaggat tgttggaggc ctactacagc ggagccattg
    58921 cagagaaatt cacaggttag cctgggatgt gctggagcca ggcagaagca gggaaattaa
    58981 aatttaaaaa atttattaaa agtatgaaaa atataagttt attaaataat aaaagtgtga
    59041 tataaacagt tcatggctgc atggcaggag atgaaacgag ggagaaaagg ggatacgcta
    59101 tgaatctgaa ggaacaaacc tatgtctgtg tactggcaga gtgcggcaac attacaaagg
    59161 cggcggagcg gctgtttatt tcccagcctg cgctgagcat ttatatcagc acgctggaga
    59221 aaaatctggg cgtccgcctg tttgaccgct cgggaaagcg ttttaccctg acctggacag
    59281 gggagatgta cgtggaaaag gccagaaaga tgctggactt gaaggcagag tttgacgagg
    59341 gtctggcgga gattaccgga gagcgggcag ggcggcttcg gattggagtc cagcttcggc
    59401 gcgagacctg gctgatcccg ccggttttag cgcggtttaa aagcgaatat cccagaattc
    59461 aggtagttat tcaggagggc aaccataagg agctgatgca gatgttcaat gcctatgagc
    59521 tggatctggt tctgatgaac ggggcggacg ttaagggcgg tatgcaggct caggagctgt
    59581 tttcggagga gctgttaatc gcagttcccc agctttctcc cctgaacgag aaggctgtct
    59641 gggcggaggg atcccgctat cggtatcttg atttgaaatg gctgaacggc cagaacgtca
    59701 ttctgcccta tccggggcag agcctccggg ccgatgtgga ggctgtgctg aaaagcgagg
    59761 gaattaccct gggccggatt gagaccatcc gaaatattga gatggctatg cagatggtgg
    59821 cggaaggtct gggaatcggc tttaaccggg aatattacgc catgaatatg aagtacagaa
    59881 agagagtcaa ttattacacg atgggggcca cggctcccaa gacagccttt gtggccggat
    59941 acagaaagga tatccatgtg acggagccca tgcagaggtt tatcgcgctg tgccggcagc
    60001 aggcctacac agagtgggag agcctggctc aatagattat aagtttttta aatagttaaa
    60061 ttaaaaaaag tgaattatac agaaacctcc tttaccggta tactgaaagc acgaaagcga
    60121 atccggaaaa ggaggttttt atgatggata aaaaggggat gtacgcctgt attgacagta
    60181 aggcgctgga gcttacagag atggctgacg atattttcga ccatccggag ctgggcctgt
    60241 ctgaattcag ggcgtccggg cttctgacaa gctggctgga gaaggaaggc ttccaggtgg
    60301 aaaagggagc cggcggcctg gagacggcct ttaaggctgt cttcaaaaaa ggcgagggcg
    60361 gtccgaatat tggacttctc tgcgagtatg acgcgcttcc gggcattgga catgcctgcg
    60421 gccatcacat gcagggaccg tctattttag gagcggcggc agctcttaaa aacgcagggc
    60481 cagatggaaa ctacaccatt acagtgtacg gaactccggc agaagagagc gtcagcggaa
    60541 aaattttgat gattaagaat ggagtgaatt ttgaggagct ggacgtggcg ttaatgatgc
    60601 acggaaacgg atgcacccag gtagacgtaa agtccctggc tctttccaag ttcaaggtta
    60661 tctaccacgg agtcagcgcc catgcggccg ttaagcctga aaagggcaga agcgcattgg
    60721 acggactgat tttagcattc cagggaatcg agttcctgcg ggagcacgtg gcggacgatg
    60781 tgaagatgca ctacacagtc gtaggctgcg gaggaactcc ggctaacatt gtgccggaga
    60841 cggcagaggc cagcttctat gtccgctcct acaacagaac gtacctgaac acagtgatcg
    60901 agcggtttaa aaaggtgctt cagggcgcgg ccatgatgac tgagacagag gtggagatca
    60961 ttgaggaaaa gggaatcgac agcaagattc catgcctgaa gctgaacgac ctgattatgg
    61021 ccaacgcaga ggcagtgaac gctccccgca tccgcgctcc gagagagaag accggatcca
    61081 cagactttgg aaacattatg caccgggtgc caggctcctg catccgagtg gcctttgtag
    61141 aggaaggcgc agcttcccac tctcaggatt ttgtaaacgc aggaaagaca gaggaggctc
    61201 atcaggcagt tgtttacgga gctaagattc tggcaggaac agcggcagac ctgattgcag
    61261 atccgaagct tctggcagag gtgaaggaag agttccagac acgaaagaaa caggaaagtt
    61321 ctatctaagg aagagaggca taccatgagc gaaaagacaa aaaaaccctt taaaatgccc
    61381 cataccttcg taattatttt tacgattatt ctggcggcag tagccttaac ctggattatc
    61441 ccggcaggcc agtatgtgag atttgagaat gcccagggaa tcgaggttat cgatccaaac
    61501 cagtttaact acattgacag gactccggta aatccgtttt taattcctct ttacattgta
    61561 aaggccttta ttaagcagat tgacctgatg ctcgttatcc tgtttgcagg cggcgccttc
    61621 cacatgatta ctcagacagg agcgcttcac gcaatcgtgg caaagttagc gaaggcattc
    61681 tctaaccgtc tgtacatttt cattccgctg cttacccttg tattcggact gatctgtacc
    61741 acacagggcg ttaacctttt tatcgccttt gcgccgatta tggtcatgtt agccatggcc
    61801 atggggctgg actccatcac cggagcttcc attatcctgc tgggaggagc ggtaggcttt
    61861 tccacaggcc cgttaaatat taacacaacg attgtagccc agaagattgc ggagcttccg
    61921 ctctactctg gaatcggata ccgttttgtc tgcttcggcg tattttacgt agtgacaaac
    61981 atctacctgc tccgctacgc catgaagatt cacaagaatc ctgagttaag cccaatgtac
    62041 gatctggata agcagagcga gttcaaggac ggcgctgatc tggaatcctt tggaacgatg
    62101 aatctcagaa agtccctgat tatgatcgca ttctttgcag ccctgattgc tattgtatac
    62161 ggcggcgtaa agcttgactg ggatatggaa gagacagcgg ccatgttctt aggcctcgcg
    62221 ttagtggcag gcgtaatcgc aggctttaac ccatccaaga tttccaagga cttcctggac
    62281 ggctgcaaga agatgctggg cgcagccttt atcatcggta tggccacagc cattggaacg
    62341 attatgaagt ctggaaatat cattgacaca gtcgttcacg ctctggcagg cggactttct
    62401 aatgtaccga gcatccttca ggctccggcc atgctgctgg caaacacaat tatcaacgta
    62461 ttccttacat caggaagcgg ccaggcagcg gcagttatgc cgattatgac tccgctctcc
    62521 gacctgatcg gcgtgacaag acagacagct gtcttagcct tcaactttgg agacggattc
    62581 tgtaactacg tgcttccgac ctccactgct ctgatgggaa ttatcggcgc tgccaatatt
    62641 ccttatgaca gatggatgaa gttcatgtgg aaactgttcc tcatctggtt aggagtagga
    62701 acagtgctct taatgattgc ccaggtaatg cattacggtc caatgtaggc ttgatcctgg
    62761 caggacagac agaggctctg tcccaaaccc tgaaacccat aaccaacaat aatccttatg
    62821 aaaatagcgc cgctcaggcg gcaaaaaggg agaagcttag attccgggta agcttctcct
    62881 ttttgcataa atacaacttt ttttgtcaat tcaacgcatt aatgcgttat tctgcttgtg
    62941 ttttcacgga atctgtagta aactgtctgc aaaggtatta tataaaagga gaaaatggaa
    63001 atggaaagag aaaagttttc atcgcgtctg ggatttatcc tgatttctgc cggatgcgcc
    63061 attggactgg gaaacgtctg gagattccca tatattgtag gacagtacgg cggagccgcc
    63121 ttcgttctga tctacgtggc tttcctgctt ctgttaggac ttcccatcat tgtcatggag
    63181 ttcgcagtgg gacgggccag ccagaagagc gtggcgctgt cctttgacgt cttagagcca
    63241 aagggaagca agtggcatat tcagaagtgg ttcggcatgg caggaaatta cattttgatg
    63301 atgttttata caacggtagc cggatggctg gtatactact tcattaagat ggccaagggc
    63361 gatttcgtca gcctggatcc ggccggcgta tcggagcagt tttcctctat gatggccaat
    63421 ccggcgatta acgtgggatt tatggccctc gtggtagtcg tatgctttgg agtctgcgct
    63481 atgggccttc agggcggcgt ggagaaggta acgaagatta tgatggtagt gcttctggcc
    63541 ctgatggtag tgctggcgtg caattccatt atgatggaaa acagcggtcc tggactggag
    63601 ttctacttaa agcctgactt tggaaagatc aaggaggccg gaatcgggga ggtggtgttc
    63661 gccgctctgg gccagtcttt ctttaccctg agtattggta tcggagcgct ggcgattttc
    63721 ggaagctata tcggcaagga gagaaggctg acaggagagg cagtcagcgt tatgattctc
    63781 gacacgtctg tagctttcat ggccggactg atcattttcc cggcctgctt tgcctacggg
    63841 atcgaggcgg gacagggacc atccctgatt ttcgtgacgc tccccaatgt attcaacaac
    63901 atggcgggag gaagattctg gggaagcctg ttcttcgtat ttatgtcctt tgcggcaggc
    63961 tctacggtga tcgcggtgtt ccagaatatc gtgtccttcg ccacagactt gacaggctgt
    64021 tctgtcaaga aggcagttgc cgtcaatctg gtagtgatta ttctgctttc attgccctgt
    64081 gcgctgggat ttaatgtgtt aagcggaatt accccctttg gatcaggctc caccatcatg
    64141 gatctggagg actttattgt gagcaacaac ctgcttccgt taggcagtct ggtttacctg
    64201 gcgttctgta caagccgtta cggctggggc tttaagaagt tcttagctga ggcggacgag
    64261 ggaaggggaa tcaaattccc ggcgtgggcc agaatttata tttcctacgg aattccggta
    64321 attgtactgt atatcttcat tcagggatat tgggcaaaat ttgcgccgat gtttatgaaa
    64381 taggaataaa ataaagaaaa ggaagaactt ttccatgctc caccaaaagc ttagtcgctg
    64441 gaaaagttct tccttttctt tgctgtgggg gcgcagccag gaaggggatc tggcctttta
    64501 ctgtgccggc gttacccttc agaactgaaa agggatagcc aagtcagcct gcatatggta
    64561 agatggacga aagggggaaa atagtatgga tcagagatat cacagaggga agctgatact
    64621 gatagtctgc accttctgtt tttgtttatt gacagcctat tcgttcggaa gatttgaaac
    64681 gaattttttt gaaatggaga tggagaagag ccaggaagaa ctgaaaaaat cggcggaggt
    64741 ggaagcgaaa tttgtacaga attgatatga aaatatgatc gtttccttgg aagctctggc
    64801 agaaaatctg caggactttt ctctttcaca ggaagaggag gttctcaggc agctgtcgtt
    64861 tctggcagag gtagggcgct tcagttatgt aggcgtcagc gaccaggagg gcaatattat
    64921 agactccgcc gggcagaagg cgaacataca gggacgcgat tattttcagg aagccatggc
    64981 gggaaaaacg gtgatctcag atgtgatgga atcgaaagtc agaggcggga aagcgataca
    65041 ggtgatggct cttccgatta tggagcatga cggtcccagg ggaattgtat ttgggattct
    65101 caatattgac tctatggatg aaattttaga gggggagaca ggcagcgata tagacattca
    65161 gattatcgat tcccagggaa attacattct gaggaagaag aaaggccctt ttgccaagaa
    65221 aaatgcgtgg gatgaattcg aagagtatga atttattgaa ggaaacgaag aggaaatcag
    65281 ggaaaatatc aaggctcaga aggcgggaaa cctcattttc aagatgggtg aggaggagca
    65341 gtttggctat tacatgccca tggggcttcg gggctactac atctgctcga ttgtaaacgg
    65401 agagaagctg agacagtggc agaagcaggt gaatgcagaa gccagccaaa tgatgctgct
    65461 gatgacagcg gcctttttca cattgggaat cgggccgtac ctgtacaata aaaaggtgca
    65521 ggaggagctg aggagatccc acgcggaggc tgtgagcagc gaggaaatga tgggaatcgc
    65581 tatcaaggag tcctcccagg ttgtgtttga atacagcatt cagacaggga ttttgaagaa
    65641 aaaggcaggt gtatcgtttc ctctgttttc cggatccggc acagaggcaa aggtaaaggc
    65701 cgttctggac aggggaattc tggcagagga gtccgttccg gtgtttctgg agctgtttga
    65761 aaccataaaa acagaggaaa gcgtggaggg aattttcaaa gcagaagaag acggctgcgt
    65821 gaagtggtat cggattctca tgaaaaatat ttatgacgag aatcatgatc ttctgaatac
    65881 ggtgggaatc gtggacgacg tgacagagaa gaaggtgcag gaggagctgc tggaaatcgg
    65941 agagaaggag aagaaggctc ttcaaaagca ggcggagcgg gacggcctga cacagcttta
    66001 caatgcggct gccgtgaaat cgaaggtaca agagctgctg gaacacgcgg acccctattc
    66061 agactgccat ctgttcgtac tgctggattt agataatttc aaacagatca acgatacctt
    66121 tggacatcag tatggggatc aggtgttaag agaagtggcg gacgtgctga agaagacgtt
    66181 tcgcagagat gatattctgg ggcggttagg aggagacgaa tttgtgttcc tgcttcgaag
    66241 tgtgccaaac ttccaggtga tggaaccgat ctttgaaaaa ttgtgccgcc agcttcagaa
    66301 gacgtacacg aaagacggaa aatctgtgac gatttccgct tcgctgggcg cagcctgcgc
    66361 gccgggccag ggcagtacct tcacagagct ttacagcaag tcggatcagg cgctgtacga
    66421 ggtgaaaaat cagcttaaaa acggatatcg tttatatgga aattaagagg aagcgcagtg
    66481 agcgggtatg ataccttgct cactgtattt gtttctattg ccgtttatca aagaagccat
    66541 ggagtatttc tgaaaatgta aaaaatctgt caagaaatgt gcagaaatgc aaagagttga
    66601 tattgtttct gtaaaaagta aaatgatagt aaaatgaatg gtaaacttct ggttttctat
    66661 tgaatattta gaattttata gtaaaatgac acttgtttgt ataaaaaata atgagcaagg
    66721 atcaatgatt tagaggagat taccatgaaa aattataaac ttctgacacc ggggccgctg
    66781 acaaccacag ataccgtaaa gcgggtcatg atgtttgacc actgtacctg ggacgacgac
    66841 tataaacaga ttacgcagga aatcagaaaa aatcttttaa agctggccca cgtggacgag
    66901 aaggagtaca cggccgtcct gatgcaggga tcgggaagct tcggcgtgga gagcgtgctg
    66961 agcagcgtgg ttcccgagga tggcgcggtc ctgctgttaa gcaacggtgc ttacggagag
    67021 cgggcagcta agatgtgcgg ataccacaaa attccatgta ctcatgtgac ccaggaatac
    67081 aaccggaccc cggatcctgg aaaggcggag gaggccctta aaagccatcc tgaaattacg
    67141 catgtgatga tgattcacag cgagaccacc agcggaattt taaatgacat aaaaaccatt
    67201 ggagagctgg ctcataccta tgggaaaacc tttattgtag acgccatgtc gagcttcgca
    67261 ggcgtggata ttcccatgaa ggactggcag attgacttcc tgataagctc cgccaacaag
    67321 tgtatacagg gagttcccgg cttttccttt attatcgctg acagaagcct tttgatggag
    67381 acaaagggca gggccagaag cctctgcctg gatctgtacg atcagtgggc aggcatggag
    67441 aaggacggaa aatggcgtta cacctctccg acgcacgtag ttctggcttt tgcacaggcg
    67501 atgagagagc tggaggcaga gggaggcatc cctgccagac atgcccgcta tcagaggaat
    67561 atggacgttt tagtgaacaa ttttgaggag ctgggcttta agctctacgt ggacaagaca
    67621 tggcaggggc cgatcattgc caccttcctc tatccggagg gcaggaagtt tgattttcag
    67681 gatatgtact gttacatcaa ggacagaggc tacgccattt atccaggcaa gctgacagac
    67741 gcggatacct tccgaatcgg cgtgattgga gaaatctatg aggaagacat tgaaaagctg
    67801 acagagatta tgcgggaata tatggctcag gcttaaaagg gaggaacgga tgatgaagat
    67861 agaaggcgta attttcgact gggcgggaac tacggtagac tacggctgct ttgcccctgt
    67921 gagagcgttt gcagagattt tcagggagta cggcatagaa gcgactatgg aagagacgag
    67981 aaagcctatg ggaatgctga aatgggatca cattaagacc atgctttcca tggagcgcat
    68041 aaacgaagca tggatccgcg tgcacggccg cccctggaca gaccgggatg tggacgagat
    68101 gcacgacaaa tttgctgaaa agcttatggg gattctccat gagtacaccc aggtgaagcc
    68161 atttgtaaaa gaggcggtga aggagctcag aaggcggaat atcaagattg gatccaccac
    68221 cggatacaca gacgccatga tggagattgt ggttcccaga gcggctgaaa acggctacgc
    68281 gccggatttc tggatttccc ccaacagcgt gggaaacatg ggacgtccct atccctacat
    68341 gatatttgaa aatatgaggc agctgaagtt gtccgacgtc cgccgcgtga tcaaggtggg
    68401 ggacacggtt tccgacgtga aggaaggcgt ctgcgcggga gtgatttctg tgggcgtgct
    68461 ggagggaagc tctgagctgg gatactccaa ggaggagtac aacgctctca cagaggcaga
    68521 gaaaaagact gcaaaagaga aggcgtcaga gaaatttaag gaggcgggag ccgattatgt
    68581 gatcgaccac atggggcagc tggcgtctct cattgacagg ctggagaatt aaagcagagc
    68641 tgataaagac agaggaaaag ccaagttaca agaaaatcct ggcagaaatg aaaagaattt
    68701 aaaatttttc tgtaatttta gtatccttat ccatgattta atggtagaat agtaaaatga
    68761 acaggaggtg ctgcatatga aaatgatcat tgcaattatc ggaagcgaag acgcggacga
    68821 tttagtgtac gaattgaacc agaattcttt ttttgttaca aagctctcca ctatgggcgg
    68881 ttttctgaaa aagaaaagca caactcttat gctgggtgtt gacgacgcca gagtcagcga
    68941 ggccatcgcc attatcaaga agatgtccgg acagagagag cagctggtct atactccgcc
    69001 gaccatggct ggaaactgct gtccaactgt caatatgact gttcccatga acatgaaggt
    69061 aggaggctcc accgtatttg tgttaaatgt ggagaatttc cagaagtttt aaaaagctga
    69121 attgaagcaa ttaaatctaa aaaactgaaa actgaaaagc agaagccaaa agccgctgct
    69181 ctggaaatga aatatttcca gggcggcggc ttattatata gagatggaga cagaagaaag
    69241 aaaagatcta ttatagatat tatccatata tagacaatat cattaaaaat aacaattcgt
    69301 gtttagagaa tatttttggc ataattagtt tatacaaatc agaaaaagag gtaaaacagg
    69361 tgattaaaat agagcgcgta aatcattcgt ttcaagatac gcaggtttta aaagatattg
    69421 acttgacgat tcatgacaac gagatatttg gactggtggg gcccagcgga gtcgggaaat
    69481 ccacactgct caactgcctg gccgggctgg aaaaatatca gtcgggaagt atcagcgtag
    69541 acggagttaa gctggaaact ctgaatgaga tccagatgag gcagttcaga agaaatatgg
    69601 gcatgatttt tcagaatttc tctctgatcg gccgcaagga cgtgttccac aatattgcgc
    69661 ttcctatgga gtgctggaaa tattcaaagg cagagattaa aagccgggtg gatgagttgg
    69721 cggaactgac ggggatacag gacaaactga agagccgccc agacgagcta agcggaggac
    69781 agaagcagcg tgtggcgatt gcaagggctc tgtctatgaa tcccaaatat cttttctgcg
    69841 atgagtgtac atccgcgcta gatcccagat ccacggcggc aattctggag cttctgaagg
    69901 atcttcagga aaaattcaat ataaccatta ttgtggtaac acatgaaatg tcggtggttc
    69961 aaagcatttg cagccgcatg gcgattcttg acggaggctg tgtgtctctg acaggagagg
    70021 tgcaggaaat ttttgaaaat aagccggagc agctgaaacg gttaattggc ttagatgaca
    70081 gaaaaatttc tgttaccatg gatgtagaag agtttgcaaa aattaagaaa tatttgaatg
    70141 acatccgatg attcgtcccg gcatattccg tttgtattcg tctttggtag caaagaaagc
    70201 agccgatgga ccgccataga acatt
//
LOCUS       DBMDUW010000007        68941 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_450_length_68941_cov_5.042083, whole genome shotgun sequence.
ACCESSION   DBMDUW010000007 DBMDUW010000000
VERSION     DBMDUW010000007.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 68941)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 68941)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68941
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_450_length_68941_cov_5.042083"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            1..1106
                     /locus_tag="ACZPCR_02570"
                     /pseudo
     CDS             1..1106
                     /locus_tag="ACZPCR_02570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009462562.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(1209..1601)
                     /gene="rpsI"
                     /locus_tag="ACZPCR_02575"
     CDS             complement(1209..1601)
                     /gene="rpsI"
                     /locus_tag="ACZPCR_02575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012743748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HIR1229808.1"
                     /translation="MANAKFYGTGRRKKSIARVYIVPGTGNITINKRDIDEYFGLETL
                     KVVVRQPLVATETSDKFDVLVNVRGGGFTGQAGAIRHGLSRALLQADAEYRPVLKKAG
                     YLTRDPRMKERKKYGLKAARRAPQFSKR"
     gene            complement(1630..2064)
                     /gene="rplM"
                     /locus_tag="ACZPCR_02580"
     CDS             complement(1630..2064)
                     /gene="rplM"
                     /locus_tag="ACZPCR_02580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HIR1229809.1"
                     /translation="MKTFMASPATIERKWYVVDATGYTLGRLTSEVAKILRGKNKPIF
                     TPHMDCGDYVIVVNAEKIQVTGKKLDQKIYYNHSDYVGGMRETTLREMMAKKPEKVIE
                     LAVKGMLPKGPLGRSMIKKLHVYAGPEHEQAAQKPEVLEIKF"
     gene            complement(2290..3396)
                     /locus_tag="ACZPCR_02585"
     CDS             complement(2290..3396)
                     /locus_tag="ACZPCR_02585"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008396282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit C family protein"
                     /protein_id="HIR1229810.1"
                     /translation="MGIKFANGGFITTIQDMGRTGYQEFGVPAAGVMDTMAFRKANIL
                     VGNDENEAALEITLMGPMFTFTSDNIIAVTGGNLGAKLNGKDIPMYQAVLAKKGDTMS
                     FMGIKSGSRAYVAFAGGLDVPVVMGSKSTHLKSNLGGFEGRKLGPGDEIEFTAPKTAL
                     PNMSKRTVPADDYSKASCTLRVILGPQDDCFTEAGIKTFLSSTYTLTNEADRMGLRFE
                     GEKIEHKNGGDIITDGISFGAVQVPSHGQPIVMMADHQTTGGYTKIAGIISADLPKAA
                     QLKPGCKVNFQQVSVEEAQDIYVKELEELKALKEKLDYVPEKGTAKEREAVAMAVASA
                     SASGNPYTAKKKYRVVVDGEEFIVELETEVKGLR"
     gene            complement(3400..4128)
                     /gene="pxpB"
                     /locus_tag="ACZPCR_02590"
     CDS             complement(3400..4128)
                     /gene="pxpB"
                     /locus_tag="ACZPCR_02590"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017168 - 5-oxoprolinase (ATP-hydrolyzing)
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HIR1229811.1"
                     /translation="MGKVRYLAAGDSSVSVEFGNEISPEINRQIRAFKIAVEKSGIPG
                     IVETVPTYRSLLVNYKPEVIRFQDLTKEFEGLLGSLGSIVIPPPEVIEIPVLYGGEMG
                     PDIENVAKHNNKTVEEVIKIHTSEEYLIYMLGFIAGFPYLGGMSKEIATPRLTSPRVK
                     IEGGSVGIAGEQTGIYPVASPGGWQLIGRTPLKLYDAEREEPILLSAGQYIKFRSVTE
                     KEYREIEKQVADNTYKYVKYAKEV"
     gene            complement(4291..5511)
                     /locus_tag="ACZPCR_02595"
     CDS             complement(4291..5511)
                     /locus_tag="ACZPCR_02595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HIR1229812.1"
                     /translation="MGEKKDKGNMTALIGAAFLMATSAIGPGFLTQTATFTGQFKSAF
                     ALVIVATILLDVTTQLNIWSVIGVSGMRGQDIANKVVPGLGYFIACLVALGGLVFNIG
                     NVGGGATGLNVMFGLPVKAGCIISGAIGILIFLSKDAKEGMDKLTKYLGTMMILVVLY
                     VVFKSKPPVGEAVAGIASFDQAPDLVLPLITLLGGSCGGYIAFSGAHRLLDAGYKGEK
                     DLPKVRQSVLMGVGVSGTMRILLFLAVLGVVTAMPEIVGSEGWVASPPAEAFRAGAGV
                     IGYKIFGLVIFFAATTSIIGAAYTSVSFLKTLHPFIMENEKWFVIGFIAVSTVVMTLL
                     GQPATLLVLAGAVNGLILPLTLLTVLAASRNKKIVGENYKHPTILLVLGIVAVVLTGI
                     GAVRSLPNILTIFG"
     gene            complement(5560..6321)
                     /locus_tag="ACZPCR_02600"
     CDS             complement(5560..6321)
                     /locus_tag="ACZPCR_02600"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006442612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_function: GO:0017168 - 5-oxoprolinase (ATP-hydrolyzing)
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LamB/YcsF family protein"
                     /protein_id="HIR1229813.1"
                     /translation="MYFVDLNSDLGESFGNYTIGMDEEILKYVSSANVACGWHAGDPM
                     VMEKTVALAKEFGTAVGAHPGFPDLMGFGRRNMAVTPEEAKAYVKYQLGALQAFAKAH
                     GVKIQHVKPHGALYNMAAVDEKLAKAMCEAVYEVDKDIIFMGLAGSKMITAAEEIGLK
                     AASEVFADRAYNDDGTLVSRKLPGAVIKDKELAIKRVVRMVKEGKVESINGKDIDIKA
                     DSICVHGDNPKALEFVKNIRETLEKEGVTISSLMR"
     gene            complement(6532..7899)
                     /locus_tag="ACZPCR_02605"
     CDS             complement(6532..7899)
                     /locus_tag="ACZPCR_02605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HIR1229814.1"
                     /translation="MSRILIVDDEFLIRYTLEEGLRDRGHETQSAENVEEGLLKARKF
                     HPDVVLLDNLLEHSVGMDEIATFKAADPQIQVILMTAYGSVSQAVEAVKRGAYDYILK
                     PFDIDDIEMAVKRSVEKTRNQESLEYLKGESQEFLGVSPAVQQIRRHIEILGKNSSVS
                     VLIRGETGTGKEVAARLIHDISGRPGLMVRINCGAIPENLLENELFGYERGAFAGAMR
                     TKKGLIEMADGGTVFFDEVGEMPLAMQAKLLTFLDDRKIKRVGGLEDIEVDVRIIAAT
                     NRNLEKAVEQGLFRQDLFYRLNVMQLVIPPLRDRREDIPVLCDYYLDYYNKLFARSID
                     RVEPGFLREMLLYDWKGNVRELKNIFERCFLLSPGRELEKHVELNRTPDGEGARTGEY
                     FQLKDLEKGPVDLEKEVQSLERIYIEKAMGLCGGNQTKAAALLGITRFSMKRKMEKDG
                     EPEQA"
     gene            complement(7871..9223)
                     /locus_tag="ACZPCR_02610"
     CDS             complement(7871..9223)
                     /locus_tag="ACZPCR_02610"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1229815.1"
                     /translation="MRQWRNRLGNWFFQLENEILLPFLAVGIIVLGGFGVISFYNGYT
                     IEKRGLESTARQVFSVMNQDLDFLAEHVPEEEIREKYRENQPEYLRITDRDGQIIACP
                     SEPPEEEEVVLSDSGNVLDWKLEFIVDEKVLFEQILESQSYVVIGAIAALIIIIQASI
                     FISYNIAFPIRTMSRTCHEINENRGSYRTYRFDAVRRRDEIGQLATTFELLLKNMDNY
                     TKMEYTSRMSATLAHEIKNPIAGIRSGIQVLKGRVERPGDQMLCDSMIKEIDRVTSLI
                     TNLFTLSVKKDSRKEKVFLEPLVRELELFYQKGLKQQGISFSAEVSGQPSVWANGDEL
                     RQILHNLIGNSVKALGKKAGGSIRLEARAERERGGVMTLSDNGCGMTREELERAAEPF
                     YTKSINGIGLGLAIVKKLTDQNGGFFQMESQPGEGTRVSLWFPAGEEETDEPDIDSRR
                     "
     gene            complement(9220..10710)
                     /locus_tag="ACZPCR_02615"
     CDS             complement(9220..10710)
                     /locus_tag="ACZPCR_02615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HIR1229816.1"
                     /translation="MSRTLVYLIYFTLYSFLLLFIGKSSLRDSDSIAKFFVGEKKTGT
                     RALFFTFVGTWISAATILGYTGNVYQNGTRVLAVSVIPWFMGALLLYAVVSRIREYDI
                     LTIPELFEKRFHSCLLQTMSALLMAGGYILYLVIQIKGFGIAASSLLNIDYKVAVFLV
                     YLFILYSTFGGFNSVTKSDACNLIMLTISVGVVYFAVLSRIDNAGFLTDALVKERITA
                     QGFPVKGAGEFDGYSSLMYATTFFGWGMGLAANPQYLIRIVAAKDRDSARRTILWALV
                     FLAGIYFALTEIGLGLRILYPDLIEICGADDVFIYAVNNRMFSQFSGFFLLSVIGACV
                     STANSQLLLIGSSLAYDVTARIKKKKLSEERLLSLTRVYIFIGGTAALFLSLNPPEDI
                     LSFGSDIWGLFSAMFAPLIYGGLYYKNSSRKGAVAAFLTGAVCSGLFYRLHLPVYWAF
                     PATACSAAVFFAVPWLERLYRKRTGKGGNGREEQRLEGPEERRERR"
     gene            complement(11049..11786)
                     /gene="truA"
                     /locus_tag="ACZPCR_02620"
                     /pseudo
     CDS             complement(11049..11786)
                     /gene="truA"
                     /locus_tag="ACZPCR_02620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594511.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
     gene            complement(11907..12707)
                     /locus_tag="ACZPCR_02625"
     CDS             complement(11907..12707)
                     /locus_tag="ACZPCR_02625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006771843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T family protein"
                     /protein_id="HIR1229817.1"
                     /translation="MIRDITLGQYYPVDSIIHRLDPRTKLFGTMVFIVSLFMADSLWG
                     YLAATAVLAAVVRCSNVPFKFMVKGLKAVVFLLIISVSFNLFLTPGTPLVQFWIFKIT
                     REGIRLAVFMGLRLIYLVIGSSVMTLTTTPNQLTDGLEKGLHFLNKVHVPVHEIAMMM
                     SIALRFIPILVEETDKIMKAQMARGADFESGNLIQRAKSMIPILVPLFISAFRRATDL
                     AMAMEARCYRGGEGRTKMKPLKYHGADRVAYVLFFVYLAVLTVIRLAV"
     gene            complement(12704..13570)
                     /locus_tag="ACZPCR_02630"
     CDS             complement(12704..13570)
                     /locus_tag="ACZPCR_02630"
                     /EC_number="3.6.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006782210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HIR1229818.1"
                     /translation="MSVSIEVKDLNYKYSAGTAFEQQALKDVNFKVEDGEFIGLIGHT
                     GSGKSTLIQHLNGLIKASSGDILYHGESIYRDGYSMKELRSKVGLVFQYPEHQLFETD
                     VFTDVCFGPKNLGLSREETESRARHALKLVGLDESFYRQSPFELSGGQKRRVAIAGVL
                     AMRPEVMILDEPTAGLDPKGRDEILDQIERLNRQHGLTIILVSHSMEDVARYVDRLMV
                     MDHGEKVFDGTPKEVFSHCRELEEVGLAAPQVTYIIEELRERGAAIEGTITTVEEAKN
                     AILAFLGRQENV"
     gene            complement(13730..14560)
                     /locus_tag="ACZPCR_02635"
                     /pseudo
     CDS             complement(13730..14560)
                     /locus_tag="ACZPCR_02635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566481.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
     gene            complement(14894..16171)
                     /locus_tag="ACZPCR_02640"
     CDS             complement(14894..16171)
                     /locus_tag="ACZPCR_02640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HIR1229819.1"
                     /translation="MRNTKGRLRMLAAAGLSAILSVSGGLGQMTVWAASKTISKVDIE
                     LNIDLEPGDDLPDLSYGDKGSDAHVMVSDGAKYEIAEDPEWTSSVGNSGVKIGSTYTL
                     RMYLDAKDEDEYGFSGTYKSSNVKVKGGEFVSASRSGSGRLKVTVKTDPVEGTFDSPD
                     EAEWSDTTLGLAKWDAVDHVSAYDVTLYKGGSTVYKVKGYEGNKINFYPYMTSAGTYS
                     FKVRSVAKNDSQKDYAESSDWTESDEIYIGKESVSDGSGKVDYNNPNGAGNQNTAQVG
                     WIQDGNRWWYRYPDGSYPKNDWLLINNQWFLFDADGWMMTDWQFKNNNWYYLNPVSDG
                     NRGVMLTGWIHTNSGWYYLNPGPNGTVGAMYRNQWLDLNGKKYYLGDSGVMYEGWKEI
                     GHDWYYFYPGNGELAVNTTIDGFYVDGSGIWRK"
     gene            complement(16398..16934)
                     /locus_tag="ACZPCR_02645"
     CDS             complement(16398..16934)
                     /locus_tag="ACZPCR_02645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bL17 family ribosomal protein"
                     /protein_id="HIR1229820.1"
                     /translation="MAGYRKLGRTSSQRKALLRSQVTNLLYNGKIVTTEARAKEVKKI
                     AEGLIALAVKEKDNYDTVKVTAKVAKKDADGKRVKEVVDGKKVTVYEEVEKEIKKDRP
                     SRLHARRQMLKVLYDVTEVPTAKAGRKKNTKSVDLVAKMFDEIAPKYANRNGGYTRIV
                     KIGLRKGDAAMEVLLELV"
     gene            complement(17041..18000)
                     /locus_tag="ACZPCR_02650"
     CDS             complement(17041..18000)
                     /locus_tag="ACZPCR_02650"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HIR1229821.1"
                     /translation="MFDFEKPKIEIAEISEDKRYGKFVVEPLERGYGTTLGNSLRRIM
                     LSSLPGAAVSQVKIDGVLHEFSSIPGVKEDVTEIIMNIKSLAIKNSSETNEPKTAYIE
                     FEGEGVVTAADINADSDIEILNPEQVIATLSGGADSKFYMELTITKGRGYISADKNKS
                     DDLPIGVIAVDSIYTPVERVNMAVENTRVGQVTDYDKLTLDVYTNGTLAPDEAVSLAA
                     KVLSEHLNLFIDLSENARTAEIMVEKEDNEKEKVLEMNIDELELSVRSYNCLKRAGIN
                     TVEELCNRTPEDMMKVRNLGRKSLEEVLAKLKELGLQLNPSEE"
     gene            complement(18045..18638)
                     /gene="rpsD"
                     /locus_tag="ACZPCR_02655"
     CDS             complement(18045..18638)
                     /gene="rpsD"
                     /locus_tag="ACZPCR_02655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015528283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HIR1229822.1"
                     /translation="MAVNRVPVLKRCRSLDLDPIYLGIDKKSNRNSKRANKKMSEYGL
                     QLREKQKAKFIYGVLEKPFRNYYAKASRMNGQVGTNLMILLELRLDNVLFRMGFGRTR
                     KETRQIVDHKHVLVNGKCVNIPSYQVKAGDVIEIKEKFKSSQRYKDVLEVTAGRLVPA
                     WLEADQENLKGTVKELPSRDEIDVPVNEVLIVELYSK"
     gene            complement(18657..19058)
                     /gene="rpsK"
                     /locus_tag="ACZPCR_02660"
     CDS             complement(18657..19058)
                     /gene="rpsK"
                     /locus_tag="ACZPCR_02660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012201636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HIR1229823.1"
                     /translation="MAKKVSTAKKVTKKRVKKNVERGQAHIQSSFNNTIVTLTDAQGN
                     ALSWASAGGLGFRGSRKSTPYAAQMAAETATKAALIHGLKSVDVMVKGPGSGREAAIR
                     ALQACGLEVTSIKDVTPVPHNGCRPPKRRRV"
     gene            complement(19140..19508)
                     /gene="rpsM"
                     /locus_tag="ACZPCR_02665"
     CDS             complement(19140..19508)
                     /gene="rpsM"
                     /locus_tag="ACZPCR_02665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HIR1229824.1"
                     /translation="MARISGVDLPREKRVEIGLTYIYGIGRTSSNRILTEAGVNPDTR
                     VKDLTDDEVKRLAAIIAETQTVEGDLRREIAMNIKRLQEIGCYRGIRHRKSLPVRGQK
                     TKTNARTRKGPRKTVANKKK"
     gene            complement(19643..19756)
                     /gene="rpmJ"
                     /locus_tag="ACZPCR_02670"
     CDS             complement(19643..19756)
                     /gene="rpmJ"
                     /locus_tag="ACZPCR_02670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005398614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HIR1229825.1"
                     /translation="MKVRSSVKPICEKCKIIKRKGSIRVICENPKHKQRQG"
     gene            complement(20323..20784)
                     /gene="tnpA"
                     /locus_tag="ACZPCR_02675"
     CDS             complement(20323..20784)
                     /gene="tnpA"
                     /locus_tag="ACZPCR_02675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014079236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HIR1229826.1"
                     /translation="MSQANTKENRRRSNVDSSSLSHTRYKCQYHIVFIPKYRKRIMYG
                     RLKADVREIIKKLCDYRNIEIVEGAVCADHVHLCLSIPPSEKVSDVVGYIKGKSALMI
                     HDKYPESVNGWSKAFWARGYYVATVGNITEDAVKEYIQQQKEESKREDTRR"
     gene            complement(20999..21217)
                     /gene="infA"
                     /locus_tag="ACZPCR_02680"
     CDS             complement(20999..21217)
                     /gene="infA"
                     /locus_tag="ACZPCR_02680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012201639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HIR1229827.1"
                     /translation="MSKADVIEIEGTVAEKLPNAMFKVELENGHIVLATISGKLRMNY
                     IRILPGDKVTMEMSPYDLSKGRIIWRDK"
     gene            complement(21237..21512)
                     /locus_tag="ACZPCR_02685"
     CDS             complement(21237..21512)
                     /locus_tag="ACZPCR_02685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing RNA-binding protein"
                     /protein_id="HIR1229828.1"
                     /translation="MAEYKVGSLVRSLAGHDKDSFFIITEETPEYVYLSDGRLRPFDK
                     PKKKKKKHVQPTRYWDQKLTEAIESSRPTVDEEIRLFIKNWKKEREI"
     gene            complement(21541..22293)
                     /gene="map"
                     /locus_tag="ACZPCR_02690"
     CDS             complement(21541..22293)
                     /gene="map"
                     /locus_tag="ACZPCR_02690"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HIR1229829.1"
                     /translation="MAVTIKSPREIELMREAGRILAITHNELEKALKPGISTLDIDRL
                     GEEIIRSYGCTPSFKNYNGYPASICVSVNDEVVHGIPHKDHIIDEGDIVSLDAGVIYK
                     GYHSDAARTHGVGEISPEARKLIDVTRQSFFEGIKFAKPGNHLNDISTAIQAYAESFG
                     FGVVRDLVGHGIGSHLHEDPEVPNFKRRRKGILLQPGMTLAVEPMINAGSYDVVWMDD
                     DWTVVTEDGSLSAHYENTILITEDGPEILSML"
     gene            complement(22314..22955)
                     /locus_tag="ACZPCR_02695"
     CDS             complement(22314..22955)
                     /locus_tag="ACZPCR_02695"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008726443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HIR1229830.1"
                     /translation="MKIIMLGAPGAGKGTQADRIAAKHGIPHISTGDIFRSNIKEGTE
                     LGQQAKKFMDQGLLVPDEVTINMVLDRIQKGDCRNGYVLDGFPRTIPQAESLEKALAE
                     RGQKIDFALNVDVPDENIVKRMGGRRACITCGATYHIQFAPPKKDGVCDKCGSELVLR
                     DDDKPETVQKRLAVYHEQTKPLIGYYEQTGILATVDGTQEMDQVFNSIETILG"
     gene            complement(23100..24416)
                     /gene="secY"
                     /locus_tag="ACZPCR_02700"
     CDS             complement(23100..24416)
                     /gene="secY"
                     /locus_tag="ACZPCR_02700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HIR1229831.1"
                     /translation="MLKTLQNAFRVKEVRQKLVYTFMMLIVFRIGSQMPIPGANTSFF
                     DELFARYNNDAFGFLNSITGGSLTNMSVFALSITPYITSSIIMQLLTIAIPKLEEMQR
                     DGEEGRKKIQEYTRYLTVGLALMQSAAMAIGFGGQGLLLDFTALNVIVTVATMTAGSA
                     VLMWIGERITENGVGNGISIVLLFNILSTIPSDMISLYERFMQGRPVGAAALSLVIIV
                     AVIAAIVVFVIILQDAQRVIPVQYSKKMQGRKMVGGQSANIPLKVNTAGVIPVIFASS
                     LMSFPVIISEFLKVDPLSVPGQILRTLNSSSWFRPEAPIYTVGVLIYVGLIVLFAYFY
                     TSITFNPLEIANNMKKAGGFIPGIRPGKPTSDYLSGILSYIILIGACGLVIVCLIPII
                     ASGLFNINRLSFGGTSLIIIAGVILETIKAIESQLLVRNYRGFLND"
     gene            complement(24418..24858)
                     /gene="rplO"
                     /locus_tag="ACZPCR_02705"
     CDS             complement(24418..24858)
                     /gene="rplO"
                     /locus_tag="ACZPCR_02705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HIR1229832.1"
                     /translation="MELSNLQPAVGSKHSDSFRRGRGHGSGNGKTAGKGHKGQKARSG
                     ATRPGFEGGQMPLYRRLPKRGFTNRNSKTIVGINVSALERFENDTVVTVETLIEAGIV
                     KNPRDGVKILGNGELTKKLTVKVDAVSEGAKAKIEAVGGTCEVI"
     gene            complement(24881..25063)
                     /gene="rpmD"
                     /locus_tag="ACZPCR_02710"
     CDS             complement(24881..25063)
                     /gene="rpmD"
                     /locus_tag="ACZPCR_02710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HIR1229833.1"
                     /translation="MAQTLKITLVKSPIGAVPKQRATVEALGLKKLNKTVEMPDNSAV
                     RGMIQSVRHLVKVEEN"
     gene            complement(25080..25589)
                     /gene="rpsE"
                     /locus_tag="ACZPCR_02715"
     CDS             complement(25080..25589)
                     /gene="rpsE"
                     /locus_tag="ACZPCR_02715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HIR1229834.1"
                     /translation="MKRTIIDATQFELEDKVVAIKRVSKTVKGGRTMRFSALVVVGDK
                     NGHVGAGLGKAAEVPEAIRKGKEAAAKNLVAVPFDENNSIPHDFLGKFGSANVLLKKA
                     PEGTGIIAGGPARSVLELAGYKNIRTKSLGSNNKTNVVLATLAGLCALKTPEEVAKLR
                     GKSVEEILN"
     gene            complement(25610..25978)
                     /gene="rplR"
                     /locus_tag="ACZPCR_02720"
     CDS             complement(25610..25978)
                     /gene="rplR"
                     /locus_tag="ACZPCR_02720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012741341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HIR1229835.1"
                     /translation="MVSKQSRTEVRVKKHARLRNRFSGTAERPRLAVFRSNNHMYAQI
                     IDDTVGNTLVSASTAEKAVKAELTKTNNVEAAAYVGTVIAKRALEKGIKTVVFDRGGF
                     IYQGKVQALADAAREAGLEF"
     gene            complement(25996..26538)
                     /gene="rplF"
                     /locus_tag="ACZPCR_02725"
     CDS             complement(25996..26538)
                     /gene="rplF"
                     /locus_tag="ACZPCR_02725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008372550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HIR1229836.1"
                     /translation="MSRIGRMPVAIPAGVTVTIAENNLVTVKGPKGTLERELPVEMSI
                     KEEDGHIIVTRPNDLKKMKSLHGLTRTLINNMIHGVTEGYEKVLEVNGVGYRAAKQGK
                     KLTLSLGYSHPVEMEDPEGIETVLEGQNKIIVKGISKEKVGQYAAEIRDKRRPEPYKG
                     KGIKYADEVIRRKVGKTGKK"
     gene            complement(26617..27018)
                     /gene="rpsH"
                     /locus_tag="ACZPCR_02730"
     CDS             complement(26617..27018)
                     /gene="rpsH"
                     /locus_tag="ACZPCR_02730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015553834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HIR1229837.1"
                     /translation="MTMSDPIADMLTRIRNANTAKHDTVDVPASKMKLAIADILVREG
                     YIKKYDIVEDNGFNTIRIELKYGKDKSEKIISGIKRISKPGLRVYANTEDMPKVLGGL
                     GIAIVSTNQGVITDKEARRLGVGGEVLAFVW"
     gene            complement(27255..27440)
                     /locus_tag="ACZPCR_02735"
     CDS             complement(27255..27440)
                     /locus_tag="ACZPCR_02735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008752089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HIR1229838.1"
                     /translation="MAKTSMKIKQQRPAKFSTREYNRCRICGRPHAYLRKYGICRVCF
                     RELAYKGEIPGVKKASW"
     gene            complement(27455..27994)
                     /gene="rplE"
                     /locus_tag="ACZPCR_02740"
     CDS             complement(27455..27994)
                     /gene="rplE"
                     /locus_tag="ACZPCR_02740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013274328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HIR1229839.1"
                     /translation="MARLKEIYQSEIVDAMMKKFGYKNIMEVPKLDKIVVNMGVGEAK
                     ENAKVLDSAVRDMEIITGQKAVLTKAKKSVANFKIREGMAIGCKVTLRGEKMYEFADR
                     LINLALPRVRDFRGVNPNAFDGRGNYALGIKEQLIFPEIEYDKVDKVRGMDVIFVTTA
                     KTDEEARELLTLFNMPFAK"
     gene            complement(28016..28321)
                     /gene="rplX"
                     /locus_tag="ACZPCR_02745"
     CDS             complement(28016..28321)
                     /gene="rplX"
                     /locus_tag="ACZPCR_02745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HIR1229840.1"
                     /translation="MHKIKKGDLVKIITGKDKDKTGKILAVNTKKNTVTVEGCNMVTK
                     HTKPSAQNQQGGIVHQEGPVDISNVMLVVDGKATRVGFQTVDGKKVRVAKATGKVID"
     gene            complement(28335..28703)
                     /gene="rplN"
                     /locus_tag="ACZPCR_02750"
     CDS             complement(28335..28703)
                     /gene="rplN"
                     /locus_tag="ACZPCR_02750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HIR1229841.1"
                     /translation="MIQQESRLKVADNTGAKELLCIRVMGGSTRRYANIGDIIVASVK
                     DATPGGVVKKGDVVKAVVVRSVKGARRSNGSYIKFDENAAVIIKDDKNPRGTRIFGPV
                     ARELREKQFMKIVSLAPEVL"
     gene            complement(28728..28982)
                     /gene="rpsQ"
                     /locus_tag="ACZPCR_02755"
     CDS             complement(28728..28982)
                     /gene="rpsQ"
                     /locus_tag="ACZPCR_02755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005950435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HIR1229842.1"
                     /translation="MERNLRKTRTGKVVSDKMDKTIVVAIEDHVKHPLYGKIVKRTYK
                     LKAHDENNECGIGDTVKVMETRPLSKDKRWRLVEIIEKAR"
     gene            complement(29031..29237)
                     /gene="rpmC"
                     /locus_tag="ACZPCR_02760"
     CDS             complement(29031..29237)
                     /gene="rpmC"
                     /locus_tag="ACZPCR_02760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006782231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HIR1229843.1"
                     /translation="MKINKFVEDLKAKSAAELNEELVAAKKELFNLRFQNATNQLDNT
                     SRIKEVRRNIARIQTVITEKSKLA"
     gene            complement(29227..29664)
                     /gene="rplP"
                     /locus_tag="ACZPCR_02765"
     CDS             complement(29227..29664)
                     /gene="rplP"
                     /locus_tag="ACZPCR_02765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019162497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HIR1229844.1"
                     /translation="MLMPKRVKRRKQFRGSMRGKATRGNVICYGEFGLVATEPCWIRS
                     NQIEAARIAMTRYIKRGGKVWIKIFPDKPVTAKPAETRMGSGKGALEYWVAVVKPGRV
                     LFEIAGVPEETAREALRLAMHKLPCKCKIASKADLEGGDNSEN"
     gene            complement(29664..30320)
                     /gene="rpsC"
                     /locus_tag="ACZPCR_02770"
     CDS             complement(29664..30320)
                     /gene="rpsC"
                     /locus_tag="ACZPCR_02770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012741333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HIR1229845.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWYAEADFADNLVEDHKIRTYLKK
                     KLYSAGVSKIEIERASDRVKIIIYTAKPGVVIGRGGSEIEKVKAEVQKLTDKKVFIDI
                     KEIKRPDRDAQLVAENIAQQLENRVSFRRAMKSAMGRSMKAGVKGIKAAVAGRLGGAD
                     MARTEFYSEGTIPLQTLRADIDYGFAEATTTYGKTGVKVWIYKGEVLPVKGNKEGSDK
                     "
     gene            complement(30335..30721)
                     /gene="rplV"
                     /locus_tag="ACZPCR_02775"
     CDS             complement(30335..30721)
                     /gene="rplV"
                     /locus_tag="ACZPCR_02775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HIR1229846.1"
                     /translation="MARGHRSQIKRERNANKDTRPSAKLSYARVSVQKACFVLDAIRG
                     KDVQTALGIVTYNPRYASTLIKKLLESAIANAENNNQMNVENLYVAECYANKGPTMKR
                     VKPRAQGRAYRIEKRMSHITVVLDER"
     gene            complement(30750..31028)
                     /gene="rpsS"
                     /locus_tag="ACZPCR_02780"
     CDS             complement(30750..31028)
                     /gene="rpsS"
                     /locus_tag="ACZPCR_02780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015513756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HIR1229847.1"
                     /translation="MARSLKKGPFADAHLLKKVDAMNAAGQKQVIKTWSRRSTIFPQM
                     VGHTIAVHDGRKHVPVYVTEDMVGHKLGEFVATRTYRGHGKDEKKSRR"
     gene            complement(31051..31890)
                     /gene="rplB"
                     /locus_tag="ACZPCR_02785"
     CDS             complement(31051..31890)
                     /gene="rplB"
                     /locus_tag="ACZPCR_02785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HIR1229848.1"
                     /translation="MGIKTYGPYTPSRRHMTGSDFSEITKTTPEKSLVVSLKKNAGRN
                     NQGKITVRHRGGGSRRKYRIIDFKRNKKDGIPATVIGIEYDPNRTANIALICYADGEK
                     AYILAPQGLTVGTKVMSGPDAEAKVGNCLPLSDIPVGAQIHNIELYPGKGGQLVRSAG
                     NSAQLMAKEGKYATLRLPSGEMRMVPIICRATIGVVGNGDHNLINIGKAGRKRHMGIR
                     PTVRGSVMNPNDHPHGGGEGKTGIGRPGPCTPWGKPALGLKTRKKHKQSNKLIVRRRN
                     ANK"
     gene            complement(32005..32304)
                     /gene="rplW"
                     /locus_tag="ACZPCR_02790"
     CDS             complement(32005..32304)
                     /gene="rplW"
                     /locus_tag="ACZPCR_02790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HIR1229849.1"
                     /translation="MANIQYYDVILKPVVTEKSMNAMSEKKYTFLVHTEANKTMIKEA
                     VEKMFPGTKVAAVSTMNLDGKTKRRGMVFGKTAKTKKAIVKLTEDSKEIEIFAGL"
     gene            complement(32304..32918)
                     /gene="rplD"
                     /locus_tag="ACZPCR_02795"
     CDS             complement(32304..32918)
                     /gene="rplD"
                     /locus_tag="ACZPCR_02795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012741328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HIR1229850.1"
                     /translation="MANVSVYNIEGNEVGTLELNDAVFGVEVNEHLVHLAVVAQLANK
                     RQGTQKAKTRSEVSGGGRKPWRQKGTGHARQGSTRAPQWTGGGVVFAPTPRDYTIRLN
                     KKEKRLALKSALTSRVNENKFIVVDELNFAEIKTKKFAEVMKNLKVEKALVVGADENA
                     ALSARNIPTVKTAFVNTINVYDILKYNTVVATKAAVASIEEVYA"
     gene            complement(32947..33582)
                     /gene="rplC"
                     /locus_tag="ACZPCR_02800"
     CDS             complement(32947..33582)
                     /gene="rplC"
                     /locus_tag="ACZPCR_02800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007707688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HIR1229851.1"
                     /translation="MKKAILATKVGMTQIFNEDGVLTPVTVLQAGPCVVTQVKTVEND
                     GYDAVQVGYVDKREKLVTKPVKGHFDKAGVSYKRYVREFRFENASEYSVKDEIKADIF
                     AAGDKIDATAVSKGKGFQGAIKRHGQHRGPMAHGSKFHRHQGSNGSATTPGRVFKGKG
                     MPGHMGNVKVTIQNLEIVRVDAENSLILVKGAVPGPKKSLVTIKETVKARK"
     gene            complement(33687..34004)
                     /gene="rpsJ"
                     /locus_tag="ACZPCR_02805"
     CDS             complement(33687..34004)
                     /gene="rpsJ"
                     /locus_tag="ACZPCR_02805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012741326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HIR1229852.1"
                     /translation="MASQVMRITLKAYDHQLVDQSAAKIIETVKKNGSKVSGPVPLPT
                     KKEVVTILRAVHKYKDSREQFEQRTHKRLIDIITPSQKTVDALSRLEMPAGVYINIKM
                     KNK"
     gene            complement(34621..34824)
                     /locus_tag="ACZPCR_02810"
     CDS             complement(34621..34824)
                     /locus_tag="ACZPCR_02810"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6199 family natural product biosynthesis
                     protein"
                     /protein_id="HIR1229853.1"
                     /translation="MIEILQVLCMFAIGVFLIAKPDLVWKIENFLYVKDGSPTQFYFI
                     LARSCGGIAIICSFVFGYVVLFE"
     gene            complement(34975..36342)
                     /locus_tag="ACZPCR_02815"
     CDS             complement(34975..36342)
                     /locus_tag="ACZPCR_02815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008396334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HIR1229854.1"
                     /translation="MKRKRIAAAVLSIMLTMAGAAVCFGASGWQKSGSNWVYYDTNGR
                     KVTNEWQKGADGLWRYLDYNGNMALNSWVDGDYYVDANGIMVAGKCMKLAKKDDGWDN
                     NAEQAWYYFTSDGKAASDSWQKISDKWYYFNGDGEMQTGWADDDLYYLGDDGTMRTGW
                     QYLEDPDADDNDDDDVRPYEDDDDHHWYYFQSSGKRYVPETGGDSFKKYKIDGVNYYF
                     DEEGRMQTGWICVSGDEDNFKDYRYLQDNGKLTTGWYSTYPPEDYEGDVEDEVQWYYF
                     GNDGEPKVGPSVENASVKDLEKINGITYLFDENGNPVYGLRNLNNGSDFETYYFGDRQ
                     TSSVQKGKMTIEEGDGTKSEFYFTESGGKAGRGFTGVKNKYLFYKGKLQEADDGTKYE
                     VICVEGRNYLVNTSGKVMEDTTVKDSSGTKFETNKTGVVVKVDKESDNGDEYARDPYE
                     PVEWD"
     gene            36628..37488
                     /locus_tag="ACZPCR_02820"
     CDS             36628..37488
                     /locus_tag="ACZPCR_02820"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007869359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HIR1229855.1"
                     /translation="MWIADGWKDYEVLDCSRGEKLERWGKYLLVRPDPQVIWDTPKKN
                     KGWKRMNGHYHRSSKGGGEWEFFDLPEQWSIHYKELTFNLKPFSFKHTGLFPEQAANW
                     DWFGDKIRKAGRPIKVLNLFAYTGGATLAAAKAGAHVTHVDASKGMVAWAKENARSSG
                     LSEAPIRWIVDDCVKFVEREIRRGNHYDGIIMDPPSYGRGPKGEIWKIEESIHPFVQL
                     CAKLLSDQPLFYLINSYTTGLAPAVLTYMLSTELVPKFGGSVRSEEIGLPVTDSGLVL
                     PCGASGRWEA"
     gene            complement(37579..38679)
                     /locus_tag="ACZPCR_02825"
     CDS             complement(37579..38679)
                     /locus_tag="ACZPCR_02825"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF013884.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HIR1229856.1"
                     /translation="MSEKQFRNKVCFAAFFFSLMVVMIHSYNADMFLTLPAFSPGGRT
                     VWAFEHILADVLGPVAVPGFFMISAYQFYRNCSFQDVVPKMERRIRTMLIPYLLWNFF
                     YYAGYALAGKIHFLAGLSDKTAVEFSIPVMAEAVLHFTYNPVFWYMHQLIFLIALSPV
                     LYPLLKNRVAGLAALLLELYCIKNLVNLPVINMDALFYYSAAAYGALHGSWLVEESWK
                     KEQTDRKKTETERTERIRRLEPWLRLLTAAAGIGLAVYFYQGITVRHSVLETVLYRFT
                     VPVTIWAAVSGTRLPEAREWMKYGFFLYTIHFILARGMNKAAAMLLPHTAAAALLVYL
                     VIPAVCVITAWKLGAFLKKHTGPFWRLINGGR"
     gene            complement(38672..39562)
                     /locus_tag="ACZPCR_02830"
     CDS             complement(38672..39562)
                     /locus_tag="ACZPCR_02830"
                     /inference="COORDINATES: protein motif:HMM:NF014566.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HIR1229857.1"
                     /translation="MKKHLLFRAFLPLAAYAVFTELALHGLAGILAAAPDGWTGAASL
                     NLSAAVLWANAAAGLAVSGLFWRQYGRGEEEGKAPERRLDLRREEIGSFLLLIALVAL
                     GICCCLGGSGLIFLLREGFSGTISSGSLSAEAISAGAKAAAAAPGTAFSLATLFLCSG
                     CIIPFAEEFLFRRAMYGSLREIRRLGRTGALILSSLMFGLYHGQLLQGIYAGLLGCLL
                     AFLYERKRTLAVPVIVHASANSAAVFLETVRYGTWLESRPGVLLIQTGAAVFLAAVIL
                     RHICRQESRAGGKRGECKFE"
     gene            complement(39562..42780)
                     /locus_tag="ACZPCR_02835"
     CDS             complement(39562..42780)
                     /locus_tag="ACZPCR_02835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002568952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HIR1229858.1"
                     /translation="MKIEKLAAAEGMPGYFPPGAVKTEGGFHICTMAEGENVSLAVFE
                     TSGGEEKQRIFPFPEGSRLGNMRTIRLLGGDFAGLSYSLICDGTEQPDPFGHAFTGRE
                     TWGELSHVKNPLRSPFELPYFDWEGDEPLHIPYEDMILYRIHARGLTMGPRGTDRKDK
                     TAGRPGTFQAIRDKIPYFRELGVTSLELMPPNEFEEVMMPDSSDGNPYGPDEPTGKLN
                     YWGYGPSLLFAPKASYSEGKPGKKNPSSEFKALVKELHKNGLELIIELYFTGKESAAF
                     ISEAVRFWVREYHVDGIHLTGIASCPSLADDPWLSRTKLFASFWEESGSEKGKQEKSR
                     HLAEYNDGFLVDMRRLLKGDEDQMNGLIFRSRRNPRNMGVINYMAHSNGFTLADSVSY
                     EMKHNEANGENNQDGSAWNYTWNCGVEGPSRKKKIVGMRQKQIRNALLILFLSQGTPL
                     LLAGDEFGATKGGNNNSYCQDNAVSWLDWRLLETNRDLFQFTKQVIAFRKKHPVFHMP
                     QEPMGMDYLVCGHPDVSYHGVKAWCPEFENFRRQLGIMYCGDYAKRPDGSSDDFFFTA
                     YNMHWEPHEFALPKLPKGMKWHLAFNTDDKDRNGIYEEGKEPCLEQQKQFLVPARTIV
                     VFIGLKDPETEKNGKKGSGKKSPKKTEKKAGKEGEKTPSKKLQKTAAAVLTAAALSLV
                     CQNPFDGSRTAFAAGPGTPAYGQGDPYNSYQWAFLNNGQFRLVTGTQNMNSSMPGHLS
                     DSQDSSDYGPETEGRATTFARAGMDINLTPARTAYDALENKGQVVVAVIDTGVQTDHE
                     DLKNSIWTNPGETAGDGVDNDKNGFVDDVHGWNFYSGKGELYQGSEDNHGTHSAGTIA
                     AGKNGVGITGICDPAYVKIMPLKVLGTKDGVGTPENVAKAIRYAEAQGASVCNLSFGT
                     GKFNQELYDTMKNSEMLFVVAAGNGDKEGKGVNLDEKPVYPAAFDLENIISVASMRLD
                     GNLEPSSNYGGSSVDLAAPGKYILSTISGGQYAYMSGTSMAAPMVSGTAALIKSARPD
                     LSTGKIREILLNSSEKNSSMEGKTTTAGMLDAGKAMELAGKA"
     gene            complement(42802..44646)
                     /locus_tag="ACZPCR_02840"
     CDS             complement(42802..44646)
                     /locus_tag="ACZPCR_02840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HIR1229859.1"
                     /translation="MNLLTIEHLTKSYTERLLFDDTAFSVNEGEKIGVIGINGTGKST
                     LLRILAGLEEPDEGSVVKGRNLYIRYLPQNPVFEPGYTVLESVIRENQGHEQVWDLEG
                     QAKTMLMTLGIPDWNEKIETLSGGQRKRAALASVLLSTADLLVLDEPTNHLDSGMADW
                     LEEYLKKFRGALVMITHDRYFLDSVTNRIVELDKGKLYSYQTNYQGFLELKAERMAME
                     EASERKRQSILRVELEWMKRGARARSTKQKGRIQRFEELSARKGPEYDGEVELGSVSS
                     RLGRTTIELKHICKAYGDKVLIQDFSYIFLKNDRVGFIGQNGSGKSTLMKMIAGWVQP
                     DSGEIEIGQTVQLGYFSQENEAMDDSLRVIDYIKEAAEYVKTPEGSISASQMLERFLF
                     PSSVQYTVIGKLSGGEKRRLYLLRILMEAPNVLILDEPTNDLDIRTLTILEDYLDSFQ
                     GIVITVSHDRYFLDRAVRRIFAFEGNGRLRQYEGGFTDYQAARQEEEAAGESLNSPSA
                     GTAVEKEMEGGPEKNTRKSWKDGQVKKLKFTYKEQKEWETIEDDIAALEEKAEALGPE
                     INKAARDYEKLAALMKEKEETEALLEEKMERWMYLNDLAERIAEQNGR"
     gene            complement(44673..45428)
                     /locus_tag="ACZPCR_02845"
     CDS             complement(44673..45428)
                     /locus_tag="ACZPCR_02845"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HIR1229860.1"
                     /translation="MKKMISWNVNGLRACVGKGFLDVFQELDADIFCIQESKLQAGQI
                     DLDIPGYYQYWSYADKKGYSGTALFTKEEPLSVVYGLGIDVHDHEGRVIAAEYEDYYV
                     VTCYTPNSQNELARLPYRMEWEDAFRSYLKKLEEKKPVIFCGDLNVAHREIDLKNPRT
                     NRKNAGFTDEERGKFSELLDAGFIDTYRHFYPDTEGAYSWWSYRFKAREKNAGWRIDY
                     FCVSESLKDRLVSASIHSEIMGSDHCPVELVIQ"
     gene            complement(45567..46715)
                     /locus_tag="ACZPCR_02850"
     CDS             complement(45567..46715)
                     /locus_tag="ACZPCR_02850"
                     /inference="COORDINATES: protein motif:HMM:NF025644.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHHW family protein"
                     /protein_id="HIR1229861.1"
                     /translation="MTEHKNRDRKKWRNFLGIAGFLAVIGAAPAFTFTLKDREFSENE
                     NRYLAQKPYISLERIKTGEFMRDMEEYVSDQLPLRDSLTTARTELLKAAGSREINGVY
                     LGKDGYLIEQWLEQDFDEERLQNNIEALNGFLEKHQDKKAFVMIVPTAAETMKDKLPP
                     HAPSFCQEKAMAQIEKGLSSGTLIDLRQTLSAHREDGVFYKTDHHWTSRGAFQGYLKW
                     CEANGMYLPASQFHPVQVSDSFQGSLDSKVLEAEGSRDSIELFTREQEPSYTVSYNFG
                     REISDSVYAPENLKKKDQYQIFLNGNHPEVTIETSNKNGRRLLIVKDSFANALVPFLI
                     GDCESIHLIDLRYYRGSLEDYISQREINEFLILYNLKNFCGEKNLKFY"
     gene            complement(46778..48142)
                     /locus_tag="ACZPCR_02855"
     CDS             complement(46778..48142)
                     /locus_tag="ACZPCR_02855"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008976379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family O-acyltransferase"
                     /protein_id="HIR1229862.1"
                     /translation="MVFSSILFIFYFLPLTLLLYYAGPSRLRNLVLLVMSLAFYSWGE
                     PVYVSIMLFSTIFDYGNGLAIEKCLSSGRKRAARAVLLLSVAGNLGILGFFKYSNFFI
                     EIINAAGGTDFPLLELSLPIGISFYTFQTMSYTIDVYLGQAGAQKNLVQFGAYVAMFP
                     QLVAGPIVKYKDISGQLADRNVTAERFSYGISRFITGLSKKVLLANNIGMVWEQISGG
                     NLAGLSAAEAWIGAAAFSFQIYFDFSGYSDMAIGLGELFGFHFQENFNHPYRSKSMTE
                     FWRRWHISLGTWFREYVYIPLGGSRKGMKRQLLNLLIVWCLTGLWHGASWNFLVWGLY
                     FGVFLTAEKLFLLRRLEALPGWVSHAYCLIFVAVSWVIFAFDSMADVCTYVKSMFGLG
                     SGGWIGEAALYYGETWGVFFVVCALCSLGIFKMKRAFLPVLFAASICFLAGGTYNPFL
                     YFRF"
     gene            complement(48154..48681)
                     /locus_tag="ACZPCR_02860"
     CDS             complement(48154..48681)
                     /locus_tag="ACZPCR_02860"
                     /inference="COORDINATES: protein motif:HMM:NF025628.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HIR1229863.1"
                     /translation="MKNKTWMKSLQKKGITAGLILASCAVLSACGGQNGQAGAGKQTE
                     SQTGKQADAGEIGKKLAEDLAFEDELTLADEDMAGMLYGIDAAVQSSVYISSGATAEE
                     IAVFEFETEEDCKEAVSLAEQRIEDQKEAFASYVPKEVKRLDGAVVKQYGRFLAVCVC
                     DDGRKAEELLAELFQ"
     gene            complement(48737..49831)
                     /locus_tag="ACZPCR_02865"
     CDS             complement(48737..49831)
                     /locus_tag="ACZPCR_02865"
                     /inference="COORDINATES: protein motif:HMM:NF024863.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDSL-type esterase/lipase family protein"
                     /protein_id="HIR1229864.1"
                     /translation="MQTDGRTAGFVGRRRQMQRARYQEQRRADRWDNDNLTRRDREYY
                     RERQRIKRRKEKRRRRIRSIVSSLEGIVLCLILISVLNYLPVFGNQGKAGRLSDVFAE
                     RNGAEAGLIWGETETEPALEGSEESLPETEAEETETEETRAEKMAVEEMTAEAEAGAY
                     DFSRPVPLSEPVDNSYFDDAVFIGDSRTEGLITNTGLSNTTAYTYKGLMVDTVFTKPV
                     IRRGENRVSVMDALKTTSFSKIYIMFGINENGWPYNDVFIHKYEEIIDAVREINPDAV
                     IYVQEIMPVTNQVSATHSYIRNGKIAEFNRLLRQMAQEKQVYFIDTASAVAASDGSLP
                     ADAAFDGIHLKKDYCKKWLDYLKSHTAAAH"
     gene            50121..51041
                     /gene="pfkB"
                     /locus_tag="ACZPCR_02870"
     CDS             50121..51041
                     /gene="pfkB"
                     /locus_tag="ACZPCR_02870"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HIR1229865.1"
                     /translation="MIYTVTFNPSLDYIVTVDQFAFGKTNRTSSEQLLPGGKGVNVST
                     VLHSLGIENTALGFLAGFTGREIEEKIRRSGVTCDFIFLKHGCSRINIKMKDFDGTEI
                     NGAGPEIDYASLEQLMSRLNSLKKGDTLVLAGSIPASMPEDSYSRILEMLKDRGVLFA
                     VDATGDLLMNVLPYRPFLIKPNNHELGEIFGVELNSREEVVPYGKKLQEKGARNVLIS
                     MAGQGAVLLDEEGGVHMLPAPRGTLVNAVGAGDSMVAGFLAGWMEKHDYSHAFRMGVA
                     AGSASAFSKFLATEQEIRSIYRTLNGASDS"
     gene            51076..53034
                     /locus_tag="ACZPCR_02875"
     CDS             51076..53034
                     /locus_tag="ACZPCR_02875"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018595509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005351 - carbohydrate:proton symporter
                     activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HIR1229866.1"
                     /translation="MRITDLIDKRSICLDGTPRTKAEALDQMVALMTASGKIADEEGY
                     RKQVYFREEESTTGIGGGIAIPHGKCSAVREPGLAAMVVRDGVEFESLDGMPAHLIFL
                     IAAPDTEDNIHLDVLSKLSVLLMDQSFVEKLTKAETAEEFLAVIDQADQEKPDIDSQL
                     AAQNGEQENSPSVSEEAEASKAKASCRILAVTSCPTGIAHTYMAAEGLEKAARAAGCS
                     LKVETRGSGGAKNVLTEQEIAEAGCIIVAADAKVPMDRFHGKKLIECPVSDGISKAEQ
                     LIERAMKGDAPVYQAGKPEAAKETKASGGAAHKIYTQLMNGVSHMLPFVVGGGILIAL
                     AFLIDGLSMDINSLSDEARSAFGTITPAAAALKGIGGIAFGFMLPILAGFIAMSIGDR
                     PALAVGFVGGMIAAGGKSGFLGALLAGFIAGYLVLFLGKLFSRLPEALEKIAPVLLYP
                     VFGILLIGLIMTFIIEPPVGFLNTSLNAALAGMSGTSKILLGIVVAGMMAVDMGGPFN
                     KAAYVFGTASIAAGNYDIMAAVMIGGMVPPCAIALATLLFKNKFTKEERESGPVNFIM
                     GLAFITEGAIPFAASDPLHVLPACVVGAGVSGALSMAFGCTLMAPHGGIFVFPVVGNA
                     MMYLAALVIGTLIGAFLLGALKKKTAEK"
     gene            53204..53965
                     /locus_tag="ACZPCR_02880"
     CDS             53204..53965
                     /locus_tag="ACZPCR_02880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015529694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HIR1229867.1"
                     /translation="MLTEKRQEEILKLLNAQGSVTVQDLKERFDASESTIRRDLTVLH
                     KKGALIKVFGGAVQADLAIDAADAQVSLRQKQHMEEKIRIARYAASLIKPDDFVYLDA
                     GTTTGAMIPFIEEKSAFFVTNAVSHGLRLVERGFRAAVLGGEIKASTEAVVGNEAYLS
                     LKKYHFTKGFWGTNGVSRISGFTTPDPNEALIKEFAMERTREPYVLCDSSKFFQTSPV
                     SFGEFSSATIITDRLPQESYRREDNIVIAKEPPAL"
     gene            complement(54011..54508)
                     /locus_tag="ACZPCR_02885"
     CDS             complement(54011..54508)
                     /locus_tag="ACZPCR_02885"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229868.1"
                     /translation="MKRRKVNKYAIRYAVLFSAFSLALHFITVYLLCHGMGLLLAGGD
                     MLNSPEKWEMREKAETIMGQAGMLGNLFIASCYLFVIITGIFLIIRKFTAIEYVAAVL
                     LFCLIQFGIFILERLINTHGMTELCNWLWAVLHQKAVWILLTLPLLISAGRYIIRMAG
                     QKKEQ"
     gene            complement(54589..55782)
                     /locus_tag="ACZPCR_02890"
     CDS             complement(54589..55782)
                     /locus_tag="ACZPCR_02890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003021282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HIR1229869.1"
                     /translation="MKKLTGSLPFRLLIGVAAGIIAGLYAGEGVMNVVVTLNYVMGQF
                     INFCVPLIIIGFIAPSITKLGNNASRMLGIALGIAYASSLGAALFSMMAGFGIIPSLS
                     INANVEGLKELPEVVFQLSIPPIMGVMSALVFSVLIGLAAAWTKAKQITGILDEFQRI
                     VLDIVKKVIIPILPVYIAMTFCSLAYEGSITKQVPVFIQVILIVMAGHYIWMALLYGL
                     AGLYSGKNPFKVLKNYGPAYLTAVGTMSSAATLAVALDCAKKSEPTLRDDMVEFGIPL
                     FANIHLCGSVLTEVFFVMVVSKILYGTLPDLPTMTLFCVLLGVFAVGAPGVPGGTVMA
                     SLGLITGVLGFDEMGTALMLTIFALQDSFGTACNVTGDGALTLMLTGYAERHKIEKQK
                     LEVEL"
     gene            complement(55935..56861)
                     /locus_tag="ACZPCR_02895"
     CDS             complement(55935..56861)
                     /locus_tag="ACZPCR_02895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006782776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HIR1229870.1"
                     /translation="MEKKPVLVIMAAGMGSRYGGLKQIDPVDHDGDLIIDFSIFDAKE
                     AGFEKVVFIIKKAIEKDFREHIGNRMEKHIQVEYVYQENDLLPEGYQVPENRVKPWGT
                     GHAILCCKDVIDGPFAVINADDYYGKAAFKELYLHLCETEDNDRYQYAMVGYKLYNTL
                     TENGHVSRGVCVADEHGYLADIHERTRVEKHGDKAEYTEDNGASWTYLPEDTLVSMNM
                     WGFTSSILEELEKRFTVFLDQNLPVNPEKCEYFLPFVVDELLKEDKAQVTVLKSADKW
                     YGVTYKEDKPMVMDAIQGLKDSGYYPKKLWED"
     gene            complement(56936..58573)
                     /locus_tag="ACZPCR_02900"
     CDS             complement(56936..58573)
                     /locus_tag="ACZPCR_02900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002568956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HIR1229871.1"
                     /translation="MISASNVTLRVGKKALFEDVNIKFVEGNCYGLIGANGAGKSTFL
                     KILSGQLEPTNGDVIITPGQRLSFLQQDHFKYDQYPVLDTVIMGNARLYQIMKEKEAI
                     YMKEDFSEEDGVKAAELEGEFATMNGWEAESDAANLLNGLGIETELHYQLVGDLTGAQ
                     KVKVLLAQALFGNPDILLLDEPTNHLDLDAIAWLEEFLINFENTVIVVSHDRYFLNKV
                     CTQIADIDYGKIQLYAGNYDFWYESSQLMIKQMKEANKKKEEKIKELQEFIQRFSANA
                     SKSKQATSRKKALEKIQLDEIRPSSRKYPYIDFRPEREIGNEVLSVENLSKTIDGVKV
                     LDNISFILNREDKVALVGPNEQAKTVLFKILAGEMEPDEGSYKWGVTTTQAYFPKDNS
                     AEFDNDDIIVDWLTQYSPVKDVTYVRGFLGRMLFAGEDGVKKVRVLSGGEKVRCMLSK
                     MMISGANVLMFDEPTDHLDMESITALNNGMTKFPGVIIFSSRDHQIVETTANRIMEIV
                     NGKLIDKITTYDEYLASDEMARKRQVFTLTETEENED"
     gene            complement(59009..59626)
                     /locus_tag="ACZPCR_02905"
     CDS             complement(59009..59626)
                     /locus_tag="ACZPCR_02905"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005612922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HIR1229872.1"
                     /translation="MEKNSKKKRRTGSGEEAGTETAGRRLYQMEYSSPIGALTLISDS
                     EALLSLEFEQKRYPFSLPERCQLTVLPGYSGNREGGEGRELLPAPLLQAARWLDCYFS
                     GKSPDFLPPLKPEGSPFRRRVWEELLRIPCGTTVTYGSIAKKLAEEEGRPHMSAQAVG
                     GAVGHNPIGIIIPCHRVVGADGSLTGFGGGIETKKALLELERAEY"
     gene            complement(59682..61670)
                     /locus_tag="ACZPCR_02910"
     CDS             complement(59682..61670)
                     /locus_tag="ACZPCR_02910"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: protein motif:HMM:TIGR00254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HIR1229873.1"
                     /translation="MKTRSIKKALPRLARTTILLLIALILPANLWAQLYAQHKNQREN
                     SSELFCQLRQLLETKERELEEDKEEFAERCIRSAEIAAYCIESRPEVTESPEAARELA
                     DRLNVDEIHCFTPEGVIYGGTHPEYYGYTFDSGEQMRYFLPMLEDTSMKLCQNITDNT
                     AEGKPMQYAAVWEKDGSGIIQIGMEPERILKAIEEKSLDRVISDIPLDMRGYLHAVDL
                     NTKRIAASTDPAMVGMDISSGLKKREGTELRTGFHERFQGKKYCVYAERYGNFALLRC
                     YPSDFPLRSIVMSTLMVFLYLVLTAVAVIGGITWYMDKKLARNLVAIVDELKKVEQGD
                     FRDISVKTDVEEFNELIFYMNQMLKGIRLGWDKLTRIVDKGRIPIGIFEKNQFFGKSF
                     INSRLLEMLGIEESGQDSLLAVSEAEKRLEEAMEHPVDEDEQIYEYDRDGDKIYLKIE
                     KQTDEQSATYYVSDLSQWWKELNELREQSSHDNLTGLYNRRGFNNRMDELFKGTQDLG
                     WGMIIMMDADGLKRINDMYGHSVGDEYLKRIGAIIKDTAGSGSVCARLGGDEFIVFLY
                     GYDSRERVDAVCGALKEKRGEAFMDNGTAELVEFSIGCAIYPVDGKNYHVLMHRADEN
                     MYLEKRERKAIYMGGGMKRKYAPKLHLKQADGRETSGK"
     gene            complement(61651..63840)
                     /locus_tag="ACZPCR_02915"
     CDS             complement(61651..63840)
                     /locus_tag="ACZPCR_02915"
                     /inference="COORDINATES: protein motif:HMM:NF012772.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HIR1229874.1"
                     /translation="MGEEMKTERKRGKIFIVITVVAAFAVLVGFFSNTVAFERMMGKI
                     VERYVSDNNYELASHISYRLKTGQEFIKDLADSLSRMPEFLMTEDLLSRKEEATELDG
                     ICVVSRENGFFPEAEETEELETWLSAHPEAWEEPQISYIKDQLMLFTAPVVKEGQAAS
                     LVIGMQSYQGIQRLVSQADYQNQGISVLMDGKTGERIIRKRGSESAITDEEWEELKEI
                     LKHRDMPYGIDKQTLSSGRQVFISAYKVEGTDWEQAAIIPSDFLMSQIERYMDIYSVF
                     TFTVMILFMFLIRHLLKENQRKEQLFLTDPLTGGWNREGFLKQCEEVIDNRNFKEYAI
                     VYLNVIDFRIINESWGEEDGNRTLQFIFHQFQKDLKQKGELVSRSSMDHFFLLLRETD
                     RNRLNSRMEEAIQEMNEVIGQKFCGTSIDFTIGVCRLQDADSVSSAMTRAISASKQKA
                     EKNVCTFYDNAVAAKQDREQRLNELFEESLKNRDLKIYLQPKVSPVPGEPCQAEALVR
                     WIHPKEGMIYPDEFIPLFEMNGNICQLDLYMFEEVCRLIARWMEEGQEISLLSVNLSR
                     FHLRSKGAGVWKEYKEIKERYNIPDGMIEIELTETVFIDDSQLLFVKSVLDGFRACGF
                     RVALDDFGFAYSSLGVLNELEVDTLKLDRTFFLNENTKSRKIVAQLIQLAHSLNMSVV
                     AEGIEQMEQVEVLKAMRCDLIQGYVYSRPIPVGEFEAWREAYENQKY"
     gene            complement(63952..66291)
                     /gene="feoB"
                     /locus_tag="ACZPCR_02920"
     CDS             complement(63952..66291)
                     /gene="feoB"
                     /locus_tag="ACZPCR_02920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003022140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HIR1229875.1"
                     /translation="MKLSELQIGNTATICAVGGSGALRQHFLDMGLIQGTEVTVVKYA
                     PMGDPIELRIHGYELTIRLADAENIEISEAHPPKETKQAAHGTQRTEKHHPGYGEGGR
                     FHNRKEENPLPEGETLTFGLVGNQNCGKTTLFNQLTGSKQHVGNFPGVTVDRKDGVIK
                     GYDNTLITDLPGIYSMSPYSSEEIVTREFVIREKPKGIINIVDATNIERNLYLTMQLL
                     ELGVPMVVALNMMDELRENGGSVLVNEMEEALGVPVIPISAAKGEGIDELIRHAIHVA
                     KYQERPLEIDFCRREEGIHRGIHAVMHLIEDHAAKAQIPLRFAASKVMEGDQTLLKQL
                     ELTENEERVLEEIAGQTEEETGMDRAASVAQMRFDYIEEVCSDAVIKPHESRERMRSR
                     EIDRFLTGKYTGIPAFIGIMGLVFWLTFNVVGAFFQGLLESGITALTEMADQAMAAAH
                     VNGAVHSLVIDGIFGGVGGVLSFLPIIVTLFFFLSLLEDSGYMARVAFIMDKLLRKLG
                     LSGRSIVPMLVGFGCTVPGVMASRTLPSERDRKMTILLTPFMSCTAKLPIYAFFTAAF
                     FPDHGALVMIGLYLFGIIMGIIMAMLMKQTAFKGEAVPFVMELPNYRMPGAKNVGHLL
                     WDKARDFLQRAFTVIFLATIAIWFLQNFDLSFNMVADSQDSVLAALAGALAPLFVPAG
                     FGDWRIVTALISGFMAKESVVSSLTVLFGSTAALQSALTLPGAAALLIFCLLYTPCVA
                     AIASVRRELGGKWALAMVFGQCLIAWIAAFGVYHLCQFL"
     gene            complement(66612..67313)
                     /locus_tag="ACZPCR_02925"
     CDS             complement(66612..67313)
                     /locus_tag="ACZPCR_02925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015528792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIR1229876.1"
                     /translation="MNKPLILVVEDDKSVNNLITTILKTHGYRYLTAMNGAAAVIEAS
                     SHNPEIVLLDLGLPDTSGVEVIKKIRSWSNMPIIVISARTEDKDKIEALDAGADDYLT
                     KPFSVDELLARLRAITRRLPVLMNQTVAENSAFVNGALRIDYAAGCAYLDGAELHLTP
                     IEYKLLCLLARNVGRVLTHTFIMQNIWGNNSADDITSLRVFMATLRKKINSSKDAPQY
                     IQTHVGVGYRMVKVE"
     gene            complement(67306..>68941)
                     /locus_tag="ACZPCR_02930"
     CDS             complement(67306..>68941)
                     /locus_tag="ACZPCR_02930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009247110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1229877.1"
                     /translation="EKLILNAPNLDVYIIPDAVSEKARYRAKKSGRSRIVFSAGDILK
                     SVSLLIAASLIGFFFYNLGIDEANIITIYVLSVLLTALVTKNQVYGLISSIVSVLVFN
                     FLFTVPRFSLRAYDAGYPLTFVVMFLAAFITGSLVMRLKSHASQSAGVAFRTSILFDT
                     NRLLQQARERDDIIQVTANQLIKLLNRDIVIYPEENGSLGEPRLFPAAGEERGEDPDR
                     SCLSEKEQKAALWTFKNNKHAGATTNTFSDAHCLYLAIRVNENVYGVLGVALAESALE
                     AFENSILLSVLGECALALENEKHIREKEEAAVLAQNEQLRANLLRAISHDLRTPLTSI
                     SGNAGNLLSMGSDLDEETKKRLYTDIYEDSMWLINIVENLLSITRLVGGQLNLNITED
                     LIEDVITEALQHVNKKSREHQITVEYEDEFMLAKMDSRLIVQVIINLVNNAVEYTPQG
                     SHIQISVKKQKDQAVISIADDGNGISDEAKKKVFDMFYSGENKVADSRRSCGIGLSLC
                     QSIINAHGGEIAVSDNVPHGAVFTFTLPAEEVRWHE"
BASE COUNT        15589 a        19539 c        15159 g        18654 t
ORIGIN      
        1 ttgggaaatg ggaagaaaaa atgctccata agattcagga gtccgtgaag cttctaaaca
       61 gggaatacct gcaaagcttt tcggtttctc cagaatcaag gacacaggat ttgcaggata
      121 tcgttctgtt tttagaagaa cgctgccgga cagagcacac gttttttgtt catgggcgtg
      181 gaaaacggaa aagcagaaat caacggtatt ttgagctttt ccacagattc cttgagcggc
      241 agaccattta tgactggcat acggcaggct ttcagggaag aaacaattat tgtaaaaccg
      301 atccggatgc aaccttcatg cacatgaaag atgaccatat aagaaatgcc cagttaaagc
      361 cgggatatta atgtacagat tgcagtagac agcggatata ttgtggcagc ggatattttt
      421 caggatagga atgatgtatg gaccctggtt tcctttttaa agacaatgga aaggaagctg
      481 gacttgcgtt atctgagtgt aacagctgat tcgggatatg aaagtgaaga agcgtatact
      541 tatctgagaa gcacaaaaca gaagccgtac ataaaaccac aaacttatga aaaatggaag
      601 aaacggaatt tcaaacagga tatcagcaaa cgtgaaaaca tgggatatga tgaaaaagct
      661 gacacataca cctgtcatgc cgggaaaaca ctgatccctg tttttgtcaa aaaaccaaaa
      721 agtaaaagtg gctatgaatc agaagtaact gtttatgaat gcgaagatta cagcgattgt
      781 ccttataaag aaaaatgcac cagagcaaaa gggaataagc ggttgtatat atcaaaaagt
      841 tttctggaaa agcgctagga atcctataaa aatatcctga gtaaaacagg gattcaatac
      901 catataaacc gttccattca agtagaagga gcttttggcg ttctgaaaca tgattacgaa
      961 ttccaaagat ttctgctccg tggaaaacca gggtaaaact ggagattctt ttgctatgca
     1021 tggggtataa tatcaataaa ctacacgcaa aaatccaaaa agagcggctg ggaagttatc
     1081 ttttttcggt taaagaaact gcttaaaaag ctcaagaacg gaagcattat taaagtacgc
     1141 caaaaaaact ccccagaatt tcgattctgg ggagttgtaa atcgtataaa attgttctga
     1201 gacagaaatt atctctttga gaactgtgga gctcttctcg cagcctttaa gccgtacttc
     1261 tttctctctt tcattctcgg atcacgtgtt aagtatcctg ccttcttgag aactggtctg
     1321 tactcagcgt ctgcctgaag aagcgctctg gaaaggccgt gacggatagc gcctgcctgt
     1381 cctgtgaaac cgccgccgcg tacgtttaca agtacgtcga acttatcgga tgtctctgta
     1441 gctacgagcg gctgacgaac tacaaccttt aatgtctcaa ggccgaaata ctcgtcgatg
     1501 tctctcttat tgattgtgat gttgcctgta cctggtacaa tatatactct ggcgatagat
     1561 ttttttcttc tgcctgttcc gtagaatttt gcgttagcca ttagtgtttc ctccttccag
     1621 cacctttaat taaaatttga tctctaaaac ttccggcttc tgagctgcct gctcatgctc
     1681 tggacctgca tatacgtgaa gtttcttaat catgcttctt cctaaaggtc cctttggaag
     1741 cattccttta actgctaact cgataacctt ctccggcttc ttagccatca tctctcttaa
     1801 ggttgtctct ctcattccgc ctacatagtc ggagtggttg tagtagatct tctgatcaag
     1861 cttcttgcct gtaacctgga tcttctcagc gtttactacg attacgtagt caccgcagtc
     1921 catgtgaggt gtgaagatcg gcttattctt tcctcttaaa atcttcgcta cctcagatgt
     1981 cagacgacct aatgtatatc ctgtagcgtc aactacatac cattttcttt caattgttgc
     2041 tggactagcc ataaaagttt tcattggttg acctcctgtt tattcagttt ttgagattaa
     2101 ctttatcaat aaaacgcctg ttccggggct ttggtacaga catttctaac tgatgtcaca
     2161 gttatacatt atattacact acgccggacg tgtcaacctc tttttccttt aaaatcaagg
     2221 ttttacggcg gtttgaaacg gccttcccgg gaaacggcag aggggacgga aaaaccgtcc
     2281 cccttgattc tatctcagtc ccttgacctc tgtttccagt tctacgataa actcctcgcc
     2341 gtctaccaca acgcggtatt tcttctttgc cgtatatgga tttccggatg ctgacgctga
     2401 cgctacggcc atggctacgg cctctctctc cttggcagtt cccttctccg gcacatagtc
     2461 cagcttctct ttcagagcct ttaactcctc cagctccttc acatagatgt cctgggcttc
     2521 ctccacagat acctgctgga agtttacctt gcagcctggc tttaactgag ctgcctttgg
     2581 aagatctgca gagataatgc cggcaatctt tgtgtatccg cctgtagtct ggtgatccgc
     2641 catcatgacg ataggctgtc cgtgggacgg aacctgcacc gcgccgaagc tgatgccgtc
     2701 tgtgataatg tctccgccgt tcttgtgctc gatcttttct ccctcgaaac gcagtcccat
     2761 acggtctgcc tcattggtca gtgtgtaggt gctgcttaaa aaggtcttga ttccggcctc
     2821 tgtgaagcag tcgtcctgcg gtcctaaaat cacgcggagc gtgcaggaag ccttcgaata
     2881 gtcgtctgcc ggaacggttc tcttgctcat attcggaaga gccgtcttgg gagccgtaaa
     2941 ctcaatttcg tccccaggtc ccagctttct tccctcaaag ccgcccagat ttgattttaa
     3001 gtgggtggat ttactgccca tcacaaccgg aacgtccagt ccgcctgcga aggccacata
     3061 ggcgcggctt ccgctcttga ttcccataaa gctcatggtg tcgccctttt tcgccagaac
     3121 agcctggtac atgggaatat cttttccgtt caacttggct cccaggtttc ctcctgtcac
     3181 ggcgatgata ttgtcagagg taaaggtaaa catggggccc atgagggtga tctccagagc
     3241 ggcctcgttc tcgtcgtttc ctaccagaat gttcgccttg cggaaagcca tggtatccat
     3301 aacgcctgcc gccggaactc cgaattcctg atagcctgtg cggcccatat cctgaatggt
     3361 tgtaataaat cctccgtttg caaacttaat gcccattctc tacacctcct ttgcgtactt
     3421 tacatattta tatgtattgt ctgcaacctg cttttcgatt tctctgtact ccttctctgt
     3481 gacggagcgg aatttgatat actgtcccgc tgagaggaga atcggctcct cccgttctgc
     3541 gtcgtagagc tttaacggcg tgcggccgat taactgccag cctcccgggg aagccaccgg
     3601 gtaaatgcct gtctgctctc ccgcgattcc cacagatccg ccctcgatct tcactctcgg
     3661 gctggtcaga cggggagtgg cgatttcctt gctcatgccg cccaggtacg ggaagcctgc
     3721 gataaagccc agcatataga tcaggtactc ctctgaagtg tggattttga tcacctcttc
     3781 caccgtctta ttgttgtgct ttgccacatt ttcaatgtca ggtcccatct ctccgccgta
     3841 gagaaccggg atctcaatca cctctggcgg cggaattaca atgcttccaa gagagcctaa
     3901 cagtccctcg aactcctttg tcagatcctg aaaccggatc acctccggct tgtaattgac
     3961 taacagagag cggtaggtag gaaccgtctc cacgattccg ggaatcccgc ttttctccac
     4021 tgcaatctta aacgcccgaa tctgtctgtt gatttccggg ctgatttcat ttccaaactc
     4081 tacgctcact gagctgtcgc ctgcagccag gtatctcacc tttcccatgc tgtttcctcc
     4141 ttatctgaat ttccagtctg ctgcctgttt ttctgatttt tctaattttt tgcaaatttg
     4201 atctttttaa tttattctgc gtatcatgtc ttttttcagc acgcgccggg aagctctaag
     4261 cccccggcgc cgcgttttgt ctatttcctc ttatccgaaa atagtaagga tatttggaag
     4321 agatctgaca gctccgattc ctgtcagaac taccgctaca ataccaagta ccagaaggat
     4381 agtcggatgc ttgtagtttt ctcccacgat tttcttattt ctgctggctg ccagaacagt
     4441 gagcagcgtc agcggaagaa tcagtccgtt gacagctcct gccagaacca gaagagtagc
     4501 cggctgtccg agcaaagtca taacgactgt agaaacggcg ataaagccga ttacgaacca
     4561 tttctcattc tccatgataa acggatgcag cgtctttaag aaggatacgg acgtataggc
     4621 tgctccgatg atggatgtgg tggccgcgaa gaagataaca aggccgaaaa tcttgtatcc
     4681 aatcacgcct gcgcctgcgc ggaaggcctc tgccggcggg ctggctaccc atccctcaga
     4741 tcctacgatc tcaggcatgg ctgtgactac gccgagaact gccaggaaca gcagaattct
     4801 catggttccg gatacgccta cgcccatgag cacggactgg cgcaccttcg ggagatcctt
     4861 ctctcccttg tagcctgcgt ccagaagtct gtgggctcct gagaaggcaa tgtagccgcc
     4921 gcagcttcct ccgagcagcg tgattaacgg aagcaccaga tccggcgcct ggtcaaagct
     4981 tgcgattccc gctaccgctt cgcctaccgg aggttttgac ttaaatacaa cgtaaagcac
     5041 aacgagaatc atcatggttc ccaggtactt tgtcagctta tccattccct ctttagcgtc
     5101 cttggaaagg aaaatcagga ttccgatggc tccggaaatg atgcagcctg ccttaacggg
     5161 aagaccgaac ataacgttca gtcccgtagc gccgccgcct acgtttccga tattgaacac
     5221 aaggccgcct aaggctacca ggcaggcgat aaaatatccc agtcccggaa ctaccttgtt
     5281 ggcgatatcc tgtcctctca tgccggatac tccgatgacg gaccagatgt ttaactgggt
     5341 agtcacgtcc agcagaatgg tcgccacaat gaccaaggcg aacgcagatt taaactgtcc
     5401 cgtaaaggtt gccgtctgtg tcaggaagcc tggtccgatg gctgaagtgg ccatcaggaa
     5461 agcggctcct atgagggcgg tcatattgcc cttatctttc ttctctccca tatgtagttt
     5521 cctccaattt tctctttttc cctatcccct tctgttttcc tatctcatca ggctggaaat
     5581 cgtcactccc tctttctcca gcgtctctct gatgttcttc acaaactcca gagcctttgg
     5641 attgtcgccg tgtacgcaga tggaatcagc cttgatatca atgtctttgc cgttgatgct
     5701 ctctaccttg ccctctttta ccatgcggac tactctctta atggccagct ccttgtcctt
     5761 gatgactgcg cccggaagct ttctggaaac cagagttccg tcgtcgttgt aggcgcggtc
     5821 tgcgaatacc tcgctggccg ccttcaggcc aatctcctca gccgctgtga tcatcttgga
     5881 tccggccagt cccatgaaaa taatgtcctt atctacctca taaacggcct cgcacatagc
     5941 cttcgccagc ttctcgtcta cagctgccat gttgtagagg gcgccgtggg gcttcacatg
     6001 ctgaatcttt acgccgtggg ccttcgcaaa cgcctgaagc gcacccagct gatattttac
     6061 gtaggccttg gcctcctcag gagtaacggc catgtttctg cggccgaatc ccatcagatc
     6121 cggaaatccc ggatgggctc ctacagctgt cccaaactcc tttgccaggg ctaccgtttt
     6181 ctccattacc ataggatctc ctgcatgcca gccgcaggct acgttagcgg aggaaacgta
     6241 ttttaaaatc tcctcgtcca ttccgatggt gtagttgccg aagctctctc ccagatcact
     6301 gtttaaatcc acaaagtaca tagcattacc tcctgttgat ttatttttct tgtttcatac
     6361 ttatgacacc ttcgtgtctc tagttaaaat tttagttgat tttatactac ttttcaattg
     6421 ttttttcttt tctttttatt tattttttag attctcaaaa aaatcgtgca gaatcgcacg
     6481 ttacaagtgt gcgattctgc acgatgtgaa tttttgcacg ttctgcccgc tctaagcctg
     6541 ctccggctcc ccgtccttct ccattttcct cttcatggag aacctggtaa tgcctaaaag
     6601 cgccgccgcc ttggtctgat ttcctccgca cagccccatg gccttctcaa tgtaaatccg
     6661 ctctaaggac tggacctcct tctccaggtc taccggtccc ttttccagat cctttaactg
     6721 gaaatactcc ccggtccgcg ccccctctcc gtccggcgtc cggttcagtt ccacgtgctt
     6781 ttccagctct ctgccggggc tcagaagaaa gcagcgctca aaaatatttt taagctccct
     6841 gacattgccc ttccagtcgt agagaagcat ctcccgcaga aaccccggct ccacccggtc
     6901 gatgcttctg gcaaacagct tattgtaata atccagataa taatcgcaga gcacgggaat
     6961 gtcttctctc ctgtctctga gagggggaat caccagctgc atgacgttga gccggtaaaa
     7021 cagatcctgg cggaacagcc cctgctccac cgccttttcc aggttccggt tggtggccgc
     7081 gataatacgc acgtccacct cgatgtcctc cagcccgcca acccgcttga ttttcctgtc
     7141 gtccaggaag gtgaggagct tggcctgcat ggctaaaggc atttctccca cctcgtcaaa
     7201 gaagacggtt cctccgtccg ccatctcaat cagacccttt ttcgtcctca tggctccggc
     7261 aaaagcgccc ctctcgtagc cgaacagctc gttttccagg agattttccg ggatggctcc
     7321 gcagttgatc cgcaccatca ggccggggcg gccgctgata tcgtggatca ggcgggccgc
     7381 tacttccttc cctgtgcccg tttctccccg gatcagaacg ctgacagagc tgtttttccc
     7441 caggatttca atgtggcggc gaatctgctg cactgccgga ctgaccccca gaaattcctg
     7501 gctctctcct tttagatatt ccagagactc ctgattcctg gtcttctcca cactgcgctt
     7561 gacagccatc tcgatatcgt cgatatcgaa gggctttaaa atatagtcgt aggccccccg
     7621 cttcaccgcc tccaccgcct gagagacgga accgtaggcc gtcatgagaa tcacctgaat
     7681 ctggggatcc gcggccttga aggtggcgat ctcgtccatt cccacgctgt gctccagcag
     7741 gttgtccaga agcaccacat ccgggtggaa tttcctggcc tttaaaagcc cctcctccac
     7801 attttccgca gactgggttt catgtcccct gtccctcagc ccctcctcca gggtgtagcg
     7861 gatcaggaat tcatcgtcta ctatcaatat ccggctcatc tgtctcctcc tctcctgccg
     7921 ggaaccagag actgactctc gttccctctc ccggctggct ttccatctgg aagaagccgc
     7981 cgttctgatc cgtcagcttt ttcacaatgg ccagccccag gccgattccg ttaatgcttt
     8041 tcgtgtaaaa tggctccgcc gcccgctcca gctcctccct ggtcatcccg catccgttgt
     8101 cgctgagagt catcacgcct ccccgttccc gctccgcccg ggcttccagg cgtatgcttc
     8161 ctccggcctt cttccctaaa gccttcacgc tgtttccaat caggttgtga aggatctggc
     8221 gcagctcgtc cccgttggcc cagacagacg gctgtcccga tacctcagca gaaaatgaga
     8281 ttccctgctg cttcagcccc ttttggtaaa acagctccag ctcccggaca aggggttcca
     8341 gaaaaacctt ctccttcctg ctgtccttct tcacggacag ggtgaacagg ttcgtgataa
     8401 gggacgtaac ccggtcaatc tccttgatca tgctgtcgca cagcatctga tcccccggcc
     8461 gctccacccg gcccttgaga acctgaatgc cggaacggat tcctgcaatg ggatttttga
     8521 tctcgtgggc cagggtggcg gacatccggc tggtatactc catcttggtg taattgtcca
     8581 tatttttcag gagcagctca aaggtagtag ccagctgtcc gatctcgtcc ctgcgccgca
     8641 cggcgtcaaa ccggtaggtc cggtagctgc ccctgttttc attgatctca tggcaggtcc
     8701 ggctcatggt ccggatgggg aaggcgatgt tgtaggagat aaaaatgctg gcctgaatga
     8761 taatgataag cgccgcaatc gccccgatca ccacatagga ctggctctct aaaatctgct
     8821 caaacagcac cttctcgtcc acaataaatt ccagcttcca gtccaggacg tttccagagt
     8881 cggaaagcac cacctcttcc tcctcaggag gttcgctggg gcaggcgatg atctgcccgt
     8941 ccctgtctgt aattctcaga tattccggct gattttccct gtatttctcg cggatttcct
     9001 cctccggaac atgttctgcc agaaagtcca gatcctgatt catcacagaa aacacctgcc
     9061 tggctgtgga ttccagccct cttttttcaa tggtatagcc gttgtaaaag gaaatcaccc
     9121 caaatccgcc cagcacgata ataccgactg ccagaaacgg aagcagaatc tcattttcca
     9181 gctgaaaaaa ccagtttccc agccggtttc tccactgtct caacgccgct ccctcctctc
     9241 ttccgggcct tccagcctct gttcttcccg gccgtttcct ccttttccag ttctttttct
     9301 gtaaagccgc tccagccagg gaaccgcgaa aaagactgcc gcagagcagg ccgtggcggg
     9361 aaacgcccag tataccggca gatggagccg gtaaaacagg ccgctgcaga ctgcgcctgt
     9421 caggaaggcc gccacagctc ccttcctgct gctgttttta taataaagtc caccgtaaat
     9481 cagcggggca aacatggcgg aaaacagtcc ccagatatcg cttccgaagg ataaaatatc
     9541 ctccggcgga tttaaggaca gaaacagcgc cgctgttcct ccgataaaaa tatagactct
     9601 cgtgagactt aaaagccgct cttcggaaag cttttttttc tttatcctgg ccgtcacatc
     9661 gtaggccaga gaagagccga tgagaagaag ctgcgaattg gcggtggaaa cgcaggctcc
     9721 gatgacgctc agcaggaaaa agccgctgaa ctgggaaaac atccgattgt tcaccgcgta
     9781 gataaatacg tcgtccgcgc cgcagatctc gattaaatca ggatacagga tccgaagtcc
     9841 cagtcctatc tccgtcaggg caaaataaat gcctgccaaa aataccagcg cccagagaat
     9901 cgtccttctg gcgctgtccc tgtccttagc cgccacaatc cggatcaggt actggggatt
     9961 agccgccagc cccatgcccc agccaaaaaa ggtggtggcg tacatcagag acgagtagcc
    10021 gtcgaactcg cccgctccct tcacaggaaa gccctgcgcg gtgatccgct cctttaccag
    10081 agcgtctgtg agaaatccgg cgttgtcaat ccggctcagc acagcaaaat agacgacgcc
    10141 cacgctgatc gtcagcataa tcaggttgca ggcgtcagat ttcgtcacag agttaaagcc
    10201 gccgaaggtg gaatagagaa tgaagagata gaccagaaac accgccacct tgtagtcgat
    10261 atttaaaaga ctggacgcgg cgattccaaa ccccttaatt tgaatcacaa gatagagaat
    10321 gtagccgcct gccatcagga gggcggacat ggtctgaaga aggcatgagt gaaaccgctt
    10381 ctcaaaaagc tccggaatcg ttaaaatatc gtactcccga atccggctta ccactgcgta
    10441 caaaagcagc gcccccataa accaggggat aacggagacc gccagcactc tggtgccgtt
    10501 ctggtacaca tttcccgtat agcccagaat ggtggcggcg gaaatccagg ttcccacaaa
    10561 ggtaaaaaag agcgccctgg ttcctgtctt cttctccccc acgaaaaact tggcaatgga
    10621 atcactgtcc ctgagagatg attttccaat gaagagaagc agaaaggaat agagcgtaaa
    10681 ataaatcaga tagaccaggg ttctgctcat gaacggacca tgccccttcc cgccgcagat
    10741 tcaggcgcat ccttataaac tgccatcaga cagccgtccc ccagagcctt tcctctctcg
    10801 tccggctcct ttaacatata gtagccgaac tgatcgccag gatggatccg gcccttcgcc
    10861 ttcacataca cgtcctgagc gccgtttctc accgcctggt ggatcacacg ccttaaaaca
    10921 ccttccagct ccttctcctc acatcgcaga acctccagaa ctgaaaatcc ctctgagagc
    10981 atacggcgct gatccaggat atagctccag tgcctgtttt ctcctgacac aaactctttc
    11041 ggctccctct catattccat gctcaccagg gtcaggcctc tggccggaat cgtaggcccg
    11101 gcggcggccc gatctctggc ctccagaatc tcctccatcc gctccggcgg ccatacgccc
    11161 atgccgattt tcaccagagt ccccatgata atgcggacca tgttgtagag gaagccgctg
    11221 ccgctgatcc gcatggtgat cacatcctcc gaatcccggt taatgtccag cctgtaaatg
    11281 gttctcaccg tctcctccgc ctgggtgcga acagtgcaga agctcttaaa atcgtgttct
    11341 cccagcagac aggccgccgc ctggcgcatc cggtccacat ccagatcaaa gtagcagaaa
    11401 tggcagtaca gcctgtttaa gggcatgtcg attttcctgt ttaaaatttt atactcatag
    11461 gtttttacgc agttggcttt tctggggtga aaggtcaggg gaacctcctc tgatttctgc
    11521 acccgcacgt cctccggaag tctctggttt accgcaaagc agattttctc ggcgggaatt
    11581 ctggcctctg tatcaaacac cgcgatattt cccctggcgt ggacgccgga atctgtccgg
    11641 ctggccccga ttacctgaat ttcttccctc aaaagctctg aaagagcttt atttaaaacc
    11701 tcctcgatag tcacgccgtt gggctgcagc tgccagccgc agtaattagt gccgtcgtag
    11761 gcaacggtca gtttaattcg tctcatattg tcattctcct gtctttccta agcgtcaata
    11821 caccaacggc ataggcttgc ttatacactt atgctgagta ctgacgtcag agcaagccga
    11881 acatgtcgca catgccggcg atggctctat acagccagcc ggatgacagt cagcacagcc
    11941 agatatacaa aaaacagcac ataggctacc ctgtctgcac cgtgatattt caagggcttc
    12001 atcttcgttc tgccctctcc gccccgatag catctggctt ccatggccat agccaggtca
    12061 gtggctctgc ggaaggcaga gataaacagc ggaaccagaa tcggaatcat gcttttcgcc
    12121 cgctgaatca ggtttccgct ctcgaaatca gcgcctctgg ccatctgagc cttcataatc
    12181 ttgtccgtct cctccactaa aatcggaata aagcgcaggg cgatggacat catcatggcg
    12241 atctcatgga ccggaacgtg aaccttattg agaaaatgaa gtcccttctc cagtccgtcc
    12301 gtcagctggt tgggcgtggt agtcagggtc atcacggaag atccgatgac cagataaatc
    12361 aggcgcagtc ccataaatac cgccagcctg attccctccc tggtaatttt aaaaatccag
    12421 aactgcacca gaggagttcc cggcgtcaga aacaggttaa agctgacact gataatcagc
    12481 agaaagacta ctgccttcag tcccttgacc ataaatttaa acggaacgtt ggaacagcgg
    12541 acgaccgccg ccaggactgc cgtagccgcc agatatcccc acaggctgtc agccataaac
    12601 agggatacaa taaataccat ggttccaaac agctttgtcc tgggatccag acggtggatg
    12661 atagaatcca ccggataata ttgtcccaga gttatatctc taatcatacg ttttcctgcc
    12721 tcccaagaaa tgccagaatt gcgttcttag cttcctccac tgtggtaatt gtgccttcaa
    12781 tagccgctcc ccgctcccgc aattcttcta taatataagt cacctgcgga gctgccaggc
    12841 caacctcttc cagctctctg caatggctga atacctcctt tggcgtcccg tcaaatacct
    12901 tttcgccgtg atccataacc atcagacggt ccacatacct ggccacgtcc tccatgctgt
    12961 gggagaccag aataatcgtc aggccgtgct gcctgttcag ccgctcaatc tggtccagaa
    13021 tctcatccct gccctttgga tccaggccgg ccgtaggctc atccagaatc atcacctccg
    13081 gccgcatggc cagcaccccg gcaatggcga cgcggcgctt ctggccgcca gaaagctcga
    13141 acggagactg cctgtagaag ctctcgtcaa gccccaccag cttcagggcg tgtcttgccc
    13201 tgctctctgt ctcctccctg gaaagcccca gattcttcgg gccaaagcag acgtccgtga
    13261 aaacgtccgt ctcgaacagc tgatgttccg gatactggaa gaccagcccc accttgctgc
    13321 gcagctcttt catggaatag ccgtccctgt atatgctctc cccatggtag agaatatctc
    13381 ccgacgaggc ctttatcagg ccattcaaat gctggatcag cgtagacttt ccagatcctg
    13441 tgtggccgat caggccgata aattccccgt cctccacctt gaagttcaca tctttcagag
    13501 cctgctgctc aaacgccgtc cctgcgctgt atttataatt taagtccttt acttcaattg
    13561 aaactgacat gtctcgttcc tctctggctg tctatctgcc tgcagcttct gtctgctctt
    13621 ccctgctttc tgtatccctg cagctgctgt ggctgccgca gctgtctcca tccgcatttc
    13681 ccgtctgtct ctctgtcaaa agttccccgg gacagcaggc cagaaacgcc tccacaaact
    13741 cttcctgtga aagaattccg tccggaagat ccactcccgc ctttttgagc tcataggcca
    13801 gctccgtcgc ctgaggcacg tccagccggt actccttcag cttttccacc tgggagaaaa
    13861 cctccctcgg cgtgccgtcc atgacaatcg ctccgtcgtc catcacgatc acccgatccg
    13921 cgtcaatgac ctcttccata tagtgggtga tcagcacagc cgttatgcct tctttccggt
    13981 tcagctcccg gactgttctg atgacctccg cccggccgtt gggatccagc atggccgtag
    14041 gctcgtccag cacaatacac tgcggcttca tggccatcac cccggcaatg gccacccgct
    14101 gtttctggcc gccggaaagg cggttcggcg atttcttccg gtaaagagtc attcccactg
    14161 ctttcaggct cttatccacc cgctcccaga tttcctctgt ggggactccc agattttccg
    14221 ggccaaagcc cacgtcctcc tccacaatat ttccaataat ctggttgtcc ggattctgaa
    14281 ataccattcc ggccgccttg cgcacgtccc agagcttctc ctcgtccgat gtgtccatcc
    14341 cggccaccca gacctctcct tctgtaggaa gcagaattcc gttcaaatgc ttggcaaatg
    14401 tggattttcc tgaaccgttg tgccccagca ccgccacaaa gctgcctttc tcaatctcca
    14461 cgttcaggtg gttgagggcc cgctttttct cttcaatttt atcttcctcg tcgcgtctga
    14521 tataatcaaa taccagtccc gctgccttaa taatattcat ctcgtttcct tcctgcgccg
    14581 tcctgggcgc ccggctcgtt tgtcgtgatg attctcatgt ctcgttaaat tttagattac
    14641 ttttatctaa gagtcaagcg gtttacacgc ttcctggaca cctgcctttc tgaggctcct
    14701 ccctctgagc gccaaagcag aaaaaagatc agaataaaag aggagaaaat ggctcccctc
    14761 tgccaggcag acgcagggac aggccagttt ctcctcatta tgatacctta ttaactttat
    14821 ccgaatctat ccgctatctg gattctatct caataaaagt ctccctaaac ctccgttctg
    14881 cggctttctg gctctacttt ctccagattc cgcttccgtc cacatagaag ccgtctatcg
    14941 tcgtattcac cgccagctcg ccgtttccag gatagaaata ataccagtcg tgtccgatct
    15001 ccttccagcc ctcgtacatc actccactgt ctcccagata atacttcttt ccgtttaagt
    15061 cgagccactg atttctgtac atggccccca cggttccgtt tggtcccgga ttcaggtaat
    15121 accagccgct gtttgtgtga atccagccgg tcagcattac tcctctgttt ccatcagaaa
    15181 ccggattcag ataataccag ttattatttt taaactgcca gtccgtcatc atccagccgt
    15241 cggcgtcaaa gaggaaccac tggttattga tcagaagcca gtcgttcttc gggtagctgc
    15301 cgtccgggta gcggtaccac cagcggtttc cgtcctgaat ccagcccacc tgagccgtat
    15361 tctgatttcc cgccccgttg gggttattat aatctacctt tccggaaccg tcggagacgg
    15421 attcctttcc aatataaatc tcgtctgact ccgtccagtc gctgctctcg gcataatcct
    15481 tctggctgtc gtttttcgcc accgagcgca ccttaaagct gtaggtgccc gcgctggtca
    15541 tatagggata aaaattaatc ttattgccct cgtagccctt caccttatag accgtgcttc
    15601 cgcccttgta gagcgttacg tcataggcgc tgacatgatc caccgcgtcc cacttggcca
    15661 ggcccagagt ggtgtcgctc cactccgcct cgtccggaga gtcgaaggtc ccctccaccg
    15721 gatccgtctt caccgtcacc ttcagcctgc cgcttccgga acggctggca gagacgaact
    15781 ctccgccctt taccttcacg ttgctggact tataggttcc gctgaaccca tactcgtcct
    15841 catccttggc gtccagatac atcctcagcg tataggtgct tccaatcttc acgccgctgt
    15901 ttcccactga gctggtccac tccgggtcct ccgcaatctc gtactttgct ccgtcagaca
    15961 ccatcacatg agcgtcgctt cccttatcgc cgtaggaaag gtccggcaga tcgtctcccg
    16021 gctctaaatc aatgttcagc tcaatatcca ccttggaaat cgtcttggag gccgcccaca
    16081 ccgtcatctg tcccagtccg ccgctcactg aaaggatggc cgacagcccc gccgctgcca
    16141 gcatccgtaa tcttcccttt gtatttctca tacctgtctc ctccttctat cactttctga
    16201 aaggtctctc cccgtatcct gcgtatctca tttctgctta ctgctgattt ctttatctta
    16261 tctttattat acgcaggtga aagcggctca gtcaacttac gatattcttt caaattctta
    16321 ataatatttc gggaggatct aaaaacccct tcgggaaaat tcccgaaggg gtttaacttt
    16381 ctgattcgat atgaaaatta tactaactca agtaaaactt ccatagctgc gtcgccctta
    16441 cgaagaccga tctttacgat tcttgtgtaa ccaccgttgc ggttagcgta cttcggagcg
    16501 atctcgtcga acatcttagc tacaaggtct acagactttg tatttttctt tcttccagcc
    16561 ttagctgtcg gaacctctgt tacgtcgtag agaaccttta acatctgtct tcttgcgtga
    16621 agtctggacg gtctgtcctt cttgatctct ttctctactt cctcgtatac agttactttc
    16681 ttgccgtcaa cgacttcctt tactctcttg ccgtcagcgt ccttcttagc tacctttgct
    16741 gtaaccttaa ctgtatcgta gttgtccttc tctttaactg caagtgcaat taagccctcg
    16801 gcgatcttct ttacttcctt agctcttgcc tcagttgtaa cgatctttcc gttgtataac
    16861 aggtttgtaa cctggcttct taataatgct tttctctggc tggaagttct tcccagcttt
    16921 ctatatcctg ccattataat atcctccatt tgtggaacat ccgtccatgc ttcttcgggc
    16981 ttactgggcg gatgcttttt gtccataaat cagtctgaat gaggatggaa gacgcgtctt
    17041 ctactcctcg cttgggttaa gctgtaagcc taactccttt aattttgcaa gcacctcttc
    17101 taaggatttg cgtccaaggt ttctcacctt catcatatcc tccggagttc tgttgcacag
    17161 ctcctccact gtattgatgc ctgcgcgttt taaacagttg tatgaacgga cggataattc
    17221 cagttcatca atgttcatct cgagaacttt ctccttctca ttgtcttcct tctctaccat
    17281 aatctcagca gttctggcat tctcggagag gtcaatgaaa aggttcagat gctcgcttaa
    17341 taccttagca gcaaggctca ccgcctcgtc tggagccagg gttccgtttg tgtaaacatc
    17401 cagagtcagt ttatcgtagt ccgtaacctg tcctacacga gtgttctcaa cggccatatt
    17461 cacgcgctca acaggagtgt agatggaatc taccgcaata actccgattg gaaggtcatc
    17521 gctcttattc ttgtctgcgc tgatatatcc gcgtcccttc gtgatagtca gctccatgta
    17581 gaacttgctg tcagcgccgc cgctgagggt agcgatcacc tgctcagggt ttaaaatctc
    17641 aatgtcagaa tctgcattga tgtcggctgc tgtcacaacg ccctcgccct caaactcgat
    17701 gtaagctgtc ttaggctcgt ttgtctcact gctgttcttg attgccagac tcttgatatt
    17761 catgataatc tcagtcacat cctctttcac gccggggatg gaactgaact catgcagaac
    17821 gccgtcgatt ttcacctgac ttactgctgc tccaggcaaa gaagagagca taattcttct
    17881 taaagaattt cctaatgtag tgccgtagcc tctctcgagg ggttccacta caaacttgcc
    17941 atatcttttg tcttctgaaa tttcagcaat ttcaattttc ggtttttcaa aatcgaacac
    18001 tactaacccc tccttttggg aagttaatta aggactgccc ttaattattt ggagtataac
    18061 tcgacgataa gcacttcgtt tacaggaaca tcaatctcgt ctctggacgg taactcttta
    18121 actgtaccct ttaagttctc ctggtcagcc tctaaccaag ccggtacaag tcttcctgct
    18181 gttacctcta atacgtcttt atatctctgt gaagatttaa atttctcttt gatctcgatt
    18241 acatcgccgg ccttaacctg gtaggacggg atgtttacgc acttgccgtt tacaagtacg
    18301 tgcttgtggt caacaatctg tcttgtctct tttcttgtgc ggccaaagcc cattctgaaa
    18361 agaacgttgt ccagtctgag ctccagaagg atcataaggt ttgtaccaac ctgtccgttc
    18421 attctggaag cctttgcgta gtaatttctg aaaggtttct ctaacacacc gtagatgaat
    18481 ttagctttct gcttctctct taactggaga ccgtactcgc tcatcttctt attagctctc
    18541 tttgaatttc tattggattt cttgtcgatt cctaagtaaa ttggatcaag gtcaagagat
    18601 ctacatcttt taagaacagg aactctattt actgccatct taactctcct cctaaattag
    18661 actcttctgc gcttcggcgg acggcatccg ttgtgtggaa ccggtgttac gtccttgatg
    18721 cttgttactt ccagaccaca tgcctgaagg gcgcggatag ctgcctcacg gcctgaacct
    18781 ggtcctttaa ccataacgtc tacagatttt aatccgtgga taagagctgc ctttgttgca
    18841 gtttctgcag ccatctgagc tgcgtatgga gtagatttcc ttgaacctct aaatcccaga
    18901 ccgcctgcac ttgcccaaga taaagcattt ccctgtgcat ctgttaaagt aacgattgtg
    18961 ttattaaaag atgactggat gtgcgcctgt ccgcgttcaa cgtttttctt tacacgcttt
    19021 tttgtcactt tcttagcagt tgacactttt ttagccattt taaactaacc tactttctct
    19081 gattttgaat cctgttaaac cgtatcacct aacctgattc acgtttgtct tgttacttat
    19141 tatttcttct tatttgctac tgttttcctt ggtcccttac gtgttctagc gttggtcttt
    19201 gtcttctgac cacgaaccgg aaggctcttt ctgtgacgga ttcctctgta gcatccgatc
    19261 tcctgaagtc tcttgatgtt catggcgatc tctcttctta aatcaccctc aacagtctga
    19321 gtctcagcga tgatagctgc cagtctctta acctcgtcgt ctgttaaatc cttaacacgt
    19381 gtgtcaggat taacgccagc ctctgtaaga atgcggttgg aacttgttct accaataccg
    19441 tagatgtaag tcaaaccgat ctctacacgt ttttctcttg gtaaatcaac acctgaaata
    19501 cgagccatgt gtgtagtaca cctccattag tttttctttc attcaatcca caagtaatgc
    19561 taaatgctta ttctatatga acaacttatc ctggtggttc ataagaaaag cggtgtgcga
    19621 aaaaaatcag gcagactttt tatcagccct gtctttgttt atgctttgga ttttcacaga
    19681 ttactctgat actgcctttt ctcttaatga tcttgcattt ttcgcaaatt ggtttaaccg
    19741 atgatctaac cttcacagta attctccttt ccgtaatagt ccgtccatct aaggacttac
    19801 aaagcgcgtt tgttacagct tgcagtcctc aaaccgcggg cctacaggta catctatcaa
    19861 acagtcccgc ccccctgtcc gcctgggttc acagctcaaa aagggcagat ctattctgat
    19921 gcctcaacaa agttcgctaa agcattataa catttatttc tatataatgc aagggatttt
    19981 ttcgctaaaa aacggtaaac gcgccaggca aaaacggcag cctttgcggc tggctgcgtt
    20041 ttctgttcgg ttcgtgcatc catgatccgc cattcgcgaa aactcgcctt acggctcaaa
    20101 cacttcgctc ggtggcggaa attagcacga acctttctgc gaaagcctcg ccgttaccgc
    20161 ccagcctgca gtttttgtct aagaaatgtc atgttgctat tactaagtca tgaaccacca
    20221 gttcaactgg tggtttgatt atgcccctat aaggggcctg tgcctgcaac gcctgaaagg
    20281 cggatgcctc aagcacttat accggctggc ctctaaaaga ggctatcttc tagtatcttc
    20341 tcttttcgat tcttcttttt gttgctgaat gtattccttt accgcatctt ctgtgatatt
    20401 gcctactgtt gcgacataat atcctctggc ccaaaaagct tttgaccatc catttacact
    20461 ttccggatat ttatcgtgta tcattaatgc actttttcct tttatgtacc ctaccacatc
    20521 tgacactttt tcgcttggtg gaatgcttaa acacaaatgt acatgatctg cgcatactgc
    20581 accttctact atttctatgt tccggtaatc gcacagtttt tttattattt ctcttacatc
    20641 tgcttttaat cttccataca taattcgttt tctatacttt ggtataaaca ctatatgata
    20701 ctggcattta taccttgtat gtgataaact actactgtcc acgttggatc gcctcctatt
    20761 ctctttagta ttggcttgag acacctttac tattgtatca taggaggctt tattacacat
    20821 tctacaacat cactactaca ctattcgccc cagcatagct gggggattag ctctttcatt
    20881 tactgttaaa gcatccattc ccggtgaaag cagctgcgca ggcaaaaaag aaaaacacgg
    20941 ccgcctagtt ccaccaaagt cacagagcgg ccgtattttt cttatttatt gctatatctt
    21001 atttatctct ccagataatg cgtcccttgg aaagatcgta cggggacatc tccatcgtca
    21061 ccttatctcc cggtaagatt ctgatgtagt tcatgcggag ctttccgctg atggttgcaa
    21121 gaacgatatg gccgttctcc agttctacct tgaacatggc gtttggcagc ttctctgcaa
    21181 cggttccctc aatttcaatt acgtctgctt tagacatttg ctctacctcc cggctgttat
    21241 atttctctct cttttttcca gttcttaata aagaggcgga tctcctcgtc tacggtagga
    21301 cggctggact caatggcttc tgtaagcttc tggtcccagt agcgggtggg ctgcacatgt
    21361 ttcttctttt tcttcttcgg tttatcgaag gggcgcagcc tgccgtctga caggtaaaca
    21421 tattccggag tttcctctgt tatgataaaa aagctgtcct tgtcgtgtcc cgcaagggaa
    21481 cggacaaggc ttccgacttt atattctgcc atgtttcacc tcaaaagtca aggcggcgtc
    21541 ctacagcata gataggattt ccgggccgtc ctcggttatc aggattgtgt tctcatagtg
    21601 ggctgacaga gaaccgtcct ccgtcacgac tgtccagtcg tcgtccatcc agaccacgtc
    21661 gtaggagcct gcgttaatca tgggctcaac ggccagcgtc atgcccggct gaagaaggat
    21721 accctttctc cggcgtttga aattcggtac ctccggatcc tcgtggagat gagagccaat
    21781 gccatgtccc accagatccc gtaccacgcc gaagccgaag ctctccgcat aggcctgaat
    21841 ggcggtggaa atgtcgttca gatgattgcc gggcttagcg aacttgattc cctcaaaaaa
    21901 gctctggcgc gtcacgtcaa tcagctttct ggcctctggg cttatctccc ccaccccgtg
    21961 agttctggcc gcgtcagaat ggtagccctt gtagataacc cctgcgtcca gactgacgat
    22021 gtctccctcg tcaatgatgt gatccttatg gggaatcccg tggaccacct cgtcgttgac
    22081 cgatacgcag atagacgccg gatacccgtt ataattttta aaggacgggg tacagccgta
    22141 gctgcggata atctcctcgc ccagcctgtc gatgtccaga gtggatatac ctggcttcag
    22201 ggccttctcc agctcattgt gggtgatagc cagaattctg cccgcttctc tcatcagttc
    22261 aatttccctt ggggatttaa tggttactgc catagttttc tgctcctgat ttcttatcct
    22321 aaaatcgtct caatgctgtt aaacacctgg tccatttcct gtgtgccgtc tactgtcgcc
    22381 agaattcctg tctgctcata gtagccgatc agaggctttg tctgctcgtg gtacacggca
    22441 agacgcttct gaaccgtctc aggcttatcg tcgtctctca gcaccagctc tgagccgcac
    22501 ttgtcgcaga ctccgtcctt cttcggcgga gcaaactgaa tgtgataggt agccccgcag
    22561 gtgatgcagg cgcggcgtcc gcccattctc tttacaatgt tttcgtccgg aacgtctacg
    22621 ttcagggcaa agtcaatctt ctgtcctctc tctgccagag ccttctccag gctctcagcc
    22681 tgcggaatgg ttctcgggaa tccgtccagc acatagccgt ttctgcagtc gcccttctgg
    22741 atgcggtcaa gaaccatgtt gatcgtcacc tcatccggaa ctaacagtcc ctgatccatg
    22801 aatttctttg cctgctgtcc cagctctgtg ccttccttaa tattgcttct gaaaatatct
    22861 cctgtggaaa tatgcggaat gccgtgtttt gctgcaatcc tgtcggcctg tgttcctttt
    22921 cccgctcccg gagcgcctaa cataatgatt ttcatagatt gtacctcccg tattcgcttt
    22981 ttcggtggat ccccaaatcc cccttcaccc ttctcttttg aaataaaaga aacgccttcc
    23041 cgcggaagca gtcagcataa aatatgcctt ccttctctcc cgcccagaag gcgaatcatt
    23101 tagtcgttca aaaagcctct gtaatttctc accaggagct gagactctat tgccttaatt
    23161 gtctccagaa tgacgcccgc aataataatt aaggacgttc ctccgaagga cagtctgttg
    23221 atattgaaca gaccggacgc gataatcgga atcaggcaca caatcaccag accgcaggcg
    23281 ccgattaaga taatgtagct cagaatacct gacagataat cagatgtagg ctttcccgga
    23341 cgaatgccag ggataaagcc gccggctttt ttcatattgt tggcaatctc aagaggattg
    23401 aacgtaatgg atgtgtagaa gtacgcaaac agcacgatca gtcctacata gattaaaact
    23461 cccactgtgt aaatcggagc ttccggacgg aaccaggaac tggagttcag ggttcttaaa
    23521 atctgccccg gaacagagag aggatcaacc ttcagaaact cagagataat aaccgggaag
    23581 ctcatcaggg aggaggcaaa aataacagga ataacgcctg ctgtatttac ctttaacgga
    23641 atgtttgcgg actggccgcc aaccatcttc ctgccctgca tcttcttaga atactgtacc
    23701 ggaatcactc tctgtgcgtc ctgaagaatg ataacaaata ctacgatagc tgcgataaca
    23761 gcaacaatga taaccagaga taacgccgct gcgccgacag gtcttccctg catgaatctc
    23821 tcgtagagag aaatcatgtc gcttggaatc gtggaaagaa tattaaagag caggactata
    23881 gagattccgt tccctacgcc gttttccgta atacgctcgc caatccacat aagaaccgcg
    23941 cttcctgctg tcatggttgc aacagtcacg atgacgttca acgctgtgaa gtcaagaagc
    24001 agtccctgtc ctccgaagcc gattgccata gcagctgact gcattaaggc cagtccgact
    24061 gtcagataac gggtatattc ctggattttc tttcttccct cttcaccatc tctctgcatt
    24121 tcctccagct tcggaatcgc aatggtcaga agctgcatga taatagagga tgtgatgtag
    24181 ggagtaatgc tcaatgcgaa cactgacatg ttcgtaaggg aaccgccagt gatcgaattg
    24241 agaaaaccga atgcatcatt gttgtatctt gcgaacagtt cgtcgaagaa actcgtattt
    24301 gcccctggaa taggcatctg tgatccgata cggaacacaa tcagcatcat aaaggtatat
    24361 acgagcttct gtcttacctc cttcactctg aaagcgttct ggagtgtttt taacatacta
    24421 gatcacctcg caggttccgc caacagcctc gattttggct tttgctcctt cacttactgc
    24481 atctactttt acagtgagct tctttgtgag ctcgccgttt ccgagaatct taacgccgtc
    24541 gcgcggattc ttaacgatac ctgcttcgat taatgtctct actgttacta ctgtgtcatt
    24601 ctcaaatctc tcaagagcgc ttacattgat gccaacaatt gtcttgctgt ttctgtttgt
    24661 gaagcctctc ttaggaagac gtctgtataa aggcatctga ccgccttcaa atcccggtct
    24721 tgtagctccg gaacgtgcct tctgtccttt atgtccctta ccagcagtct taccgtttcc
    24781 tgagccatgg ccacggcctc ttctgaagct gtcgctgtgc ttagaaccta cagctggctg
    24841 taaattggat aattccatga ctgcacctcc ttacaaaatc ttagttctct tctactttta
    24901 ctaagtgtct aacactctga atcatgcctc taacagcgct gttgtccggc atctcaactg
    24961 tcttgttgag tttctttaag cctaatgcct caacagttgc tctctgcttc ggaacagcac
    25021 cgatagggga ttttactaat gtgatcttta atgtctgtgc catttttaat ctcctcctat
    25081 tagttcagaa tctcttctac agatttaccg cggagctttg caacctcttc cggagtcttt
    25141 aatgcgcata atcctgctaa tgtagctaaa acaacgtttg tcttgttgtt ggaacctaag
    25201 gattttgtac ggatattctt atatcctgca agctccagta cggaacgtgc cggacctccg
    25261 gcgatgatac cagtaccttc cggagccttc tttaaaagca cgttagcgct tccgaatttt
    25321 ccaaggaaat cgtgtggaat gctgttattc tcatcaaatg gaacggcaac gagattctta
    25381 gcggcagcct ctttaccctt gcggatagct tccggaacct ctgcagcctt tccaaggcca
    25441 gcgcctacgt ggccgttctt gtcaccaact actactaatg cggagaatct cattgtacgt
    25501 ccgcccttga cagtcttgga tacgcgtttg attgccacta ccttatcttc taactcgaac
    25561 tgggtagcat caatgattgt acgtttcatc tgtattgttc tccttcctac tagaattcca
    25621 gaccagcctc acgtgctgcg tctgctaatg cctgaacttt accctgataa ataaatccgc
    25681 ctctgtcaaa gacaactgtt ttgataccct tctctaacgc tctcttggcg attacagtac
    25741 caacatatgc ggcagcctct acgttgtttg tcttagtaag ctcggcctta actgccttct
    25801 ctgctgtgga agcagaaact aaagtattgc caactgtatc gtcaatgatc tgagcataca
    25861 tatgattatt gcttctgaac actgctaaac gcggtctctc ggctgtgccg gaaaaacgat
    25921 tgcgtaatct agcgtgcttt ttaacgcgaa cttctgttct tgactgtttg ctaaccatct
    25981 ttacactctc cttatttatt tcttacctgt cttaccaact ttacgtctga ttacctcgtc
    26041 agcgtacttg attcccttgc ccttgtacgg ctcaggtctt ctcttgtctc tgatctcggc
    26101 agcgtactgg ccaaccttct ctttgctgat accctttacg atgatcttgt tctgtccctc
    26161 gagaactgtc tcaattccct ctggatcctc catctctacc gggtgagaat atccaaggct
    26221 taatgtaagc ttctttccct gcttagcagc tctgtaacct acaccgttta cctcgagaac
    26281 cttctcataa ccctcagtta cgccgtgaat catgttgttg attaaggttc ttgtaaggcc
    26341 gtgtaaagat ttcatcttct ttaaatcgtt cggtcttgta acgatgatat gtccgtcctc
    26401 ttccttgatg gacatctcaa ctggtaactc tctctcaagt gttccctttg gaccttttac
    26461 agtcactaaa ttgttctctg cgattgtaac agttactcct gccggaatcg caactggcat
    26521 tcttccgata cgtgacatgc ctgtttacct cctacttaga ttttcggaga agccaaggcg
    26581 gcttctctgt tttcagttat ctgtctattg attggattac caaacaaatg cgagaacctc
    26641 gccgcctacg cctaagcgtc ttgcctcttt gtcagtaatt actccctggt ttgtggaaac
    26701 gatagcgatt ccaaggccgc cgagtacctt cggcatatcc tctgtgttag cgtaaacacg
    26761 aagacctggc ttggagattc tcttgatacc ggagatgatc ttctcgctct tatcttttcc
    26821 gtactttaac tcgatgcgga tggtgttaaa accgttgtcc tcaacgatgt cgtacttctt
    26881 gatgtatccc tctcttacaa gaatgtcagc gatagctaac ttcatcttgg aagccggaac
    26941 gtctactgta tcatgtttag cagtgtttgc attacggatt ctggtaagca tatctgcaat
    27001 cggatcgctc attgtcattt tgagtttgcc tccttattct ctcttctata aagttcagcc
    27061 gcagctgggc ggtgaacccg ggagagcttc ccgctcgggc ggggctttct ccctgactat
    27121 atgggattgc tggagtggag gaagctgcag agtacatctc tccacacttt ctctgccact
    27181 atacgtccac tcgcctaggg ctcgggacgg gctttcgcac tagactcgaa aatacctcgt
    27241 caagtgctca atgcctacca gcttgctttc ttcacgcccg gaatctcgcc cttgtatgct
    27301 aactcacgga agcatacacg gcagatgccg tattttctta agtatgcgtg tggacggcca
    27361 caaattctgc agcggttgta ctctcttgtg gagaattttg ccgggcgctg ctgtttaatc
    27421 ttcattgaag tcttagccat gataatcctc ctaattattt cgcaaatggc atgttgaata
    27481 aagttaacag ttcacgagct tcctcgtctg tcttagcggt tgtaacgaaa ataacgtcca
    27541 tacctcttac cttatcaacc ttatcgtact cgatctccgg gaaaattaac tgctccttga
    27601 taccaagagc gtagtttcct cttccgtcaa atgcgttagg atttacaccg cggaagtcac
    27661 gaactcgcgg cagagccagg ttgattaaac gatctgcaaa ctcgtacatc ttctcaccgc
    27721 gaagagtaac cttgcatccg atagccatac cctctctgat cttgaagtta gccacagact
    27781 tcttagcctt agttaaaact gccttctgtc ctgtgatgat ttccatatct cttactgcgg
    27841 agtccagaac cttagcgttt tccttagcct cgccaacacc catgttgaca acaatcttat
    27901 ctaacttcgg cacttccatg atattcttgt atccgaattt cttcatcata gcgtctacga
    27961 tttcgctctg ataaatctct tttaatctag ccacttttgt tcctcctctc cgtaattagt
    28021 cgattacctt gccggtagcc ttcgcaacgc gaaccttctt gccatcaaca gtctggaagc
    28081 caactcttgt agcttttccg tcaacaacaa gcattacgtt ggaaatatca accgggcctt
    28141 cctgatgaac gatgccgccc tgctggttct gagcgcttgg ctttgtgtgc ttagtaacca
    28201 tgttgcagcc ctcaacagtt acggtattct tctttgtgtt tacggcgaga attttgccgg
    28261 tcttgtcttt atctttacct gtgataatct ttacgagatc accttttttg attttatgca
    28321 cagtcggcac ctccttacag tacttccgga gccagagata cgatcttcat gaactgcttc
    28381 tcacgaagct ctcttgctac cggcccaaaa atacgagttc ctcttgggtt cttgtcatct
    28441 ttgataatta ctgctgcgtt ctcatcgaat ttgatatagg aaccgttact gcggcgagcg
    28501 cctttcacgg aacgtacgac aacggcctta actacgtcgc ctttttttac aacaccgcct
    28561 ggtgttgcat ctttaacgga agcgacgata atgtcaccga tattagcata tcttcttgta
    28621 gatccgccca taacacgaat gcaaagaagc tccttcgcac ctgtattatc agcaaccttt
    28681 aatctggatt cctgctgaat catgccgaat actcctttct gattaaacta tcttgccttc
    28741 tcgataatct caacaagtct ccatctcttg tccttggata aaggtcttgt ctccatcact
    28801 tttacagtat caccgatgcc gcactcattg ttctcatcat gcgcctttaa tttatatgtc
    28861 ctcttaacga tcttgccgta taaaggatgc tttacgtggt cctcgatagc aacaacgatt
    28921 gtcttgtcca tcttatcgct tactaccttg ccagtacgtg tttttcttaa atttctttcc
    28981 acggtagaga ttctcctttc gattattctc tctatgcctc aaaatgcaga ttaagctaac
    29041 ttggacttct ctgtaataac agtctgaatc ctggcgatgt tcctgcgaac ttccttaatt
    29101 ctgcttgtat tatctaactg gttggttgca ttctggaatc ttaagttgaa aagttccttc
    29161 ttagcagcta ctaattcttc atttaattct gcagctgatt ttgcctttaa atcttctaca
    29221 aacttattaa ttttcactgt tatcaccgcc ttctaaatct gccttagaag caattttgca
    29281 cttgcatgga agtttgtgca ttgcaagacg taatgcttct ctcgctgttt cctctggtac
    29341 tcccgcgatc tcaaataata cgcggcctgg ctttactact gctacccagt attcaagagc
    29401 gcccttaccg gaacccattc gagtctcagc cggcttcgca gttactggct tatctgggaa
    29461 aatcttgatc caaaccttac cgccacgctt gatgtaacgt gtcatggcaa tacgggctgc
    29521 ctcaatctgg ttgcttctaa tccaacatgg ctctgtagcg actaaaccga actcaccgta
    29581 gcaaattaca tttcctcttg tagcttttcc tctcatggag ccacggaact gtttacgacg
    29641 cttaactctc ttaggcatta acattattta tcgctccctt ccttatttcc tttcacagga
    29701 agaacctcgc ccttgtaaat ccaaacctta acgcctgtct tgccgtaggt tgtggttgct
    29761 tcggcgaaac catagtcaat atctgctctt aatgtctgaa gcgggattgt gccctcgctg
    29821 tagaactctg tacgggccat atctgctccg ccaagacgtc ctgcaacggc tgccttgata
    29881 cccttaactc cagccttcat gcttctgccc atagcggact tcatagcacg acggaaggaa
    29941 acacgattct caagctgctg tgcgatgttc tctgcaacaa gctgagcgtc tctgtctggt
    30001 ctcttgattt ccttgatgtc gataaatacc ttcttgtcag taagcttctg aacctcagcc
    30061 tttaccttct caatctcgga accgccgcgg ccgattacaa cgcctggctt agctgtgtag
    30121 ataatgatct ttactctatc agatgcgcgc tcgatttcaa tcttggaaac gccggcgctg
    30181 tataatttct tcttaaggta tgttctgatc ttgtgatcct caaccagatt gtcagcaaaa
    30241 tcagcttcag cataccatct ggagtcccag tctttaataa caccgactct taagccgtgt
    30301 ggattaactt tctgtcccat atttgcctcc ttaattatct ctcgtcaagc actacagtga
    30361 tgtggctcat tctcttctcg attctgtaag ctcttccctg tgctctcggt ttaactctct
    30421 tcattgtcgg tcccttgtta gcgtagcact ctgctacata caggttctca acattcatct
    30481 ggttgttatt ctcagcgttt gcgattgctg actctaacag tttctttatt aaagtagaag
    30541 catatctggg attgtaagtt acaataccaa gtgctgtctg cacgtccttg cctctgatgg
    30601 catctaatac gaagcatgct ttctgaacgg atactctagc gtaagataac tttgcggatg
    30661 gtcttgtatc cttgttagca tttctttctc tcttaatctg ggatctatgt cctctagcca
    30721 tttgtaaaac ctcctttcaa agcttaagtc tatcgacggg acttcttctc gtccttgccg
    30781 tggcctctgt aagttcttgt ggcaacgaac tcgccgagct tgtgtcctac catatcctct
    30841 gttacgtata ccggaacatg ttttcttccg tcatgaactg caattgtgtg tcctaccatc
    30901 tgtgggaaga tagtggaacg gcgggaccag gtcttaataa cctgcttctg gcctgctgcg
    30961 ttcatagcgt cgactttctt taaaagatgc gcgtctgcaa atggtccttt tttaagtgaa
    31021 cgagccattt aattacctcc tatcaaacga ttacttgtta gcgtttcgtc ttcttacgat
    31081 taacttgttg gactgtttgt gtttctttct tgtcttaaga ccaagagctg gcttgcccca
    31141 aggtgtgcat gggcctggac gaccgatacc agtcttaccc tcaccaccac cgtgtggatg
    31201 gtcattcggg ttcataacgg aaccgcggac tgtaggtctg atacccatgt gacgttttct
    31261 accagcctta ccaatgttaa tcaggttgtg atctccgttt cctacaacgc cgatagtagc
    31321 gcggcagata atcggaacca ttctcatctc accggaaggt aatcttaatg tggcgtactt
    31381 gccctcttta gccattaact gagcggagtt accagcggaa cgaaccagct gtccaccctt
    31441 tcctggatag agctcgatgt tgtgaatctg agcaccaacc ggaatatcgg aaagcggtaa
    31501 gcagtttcct accttcgcct cagcgtccgg accggacata acctttgttc caactgtcag
    31561 tccctgtggt gccaggatgt atgccttctc gccgtctgcg tagcagatta aagcgatgtt
    31621 tgctgttctg ttcggatcgt actcgatacc gataacggtt gccgggatac catccttctt
    31681 atttctcttg aaatcgatga ttctgtattt tcttctggag ccgcctccgc ggtgtctcac
    31741 agtgatttta ccctgattgt tacggccagc gttcttcttt aaagatacta ctaaggattt
    31801 ctctggtgtt gtctttgtga tctcggagaa atcagagccg gtcatatgtc ttctggaagg
    31861 tgtatatggg ccatatgttt taattcccat gacttaaact cctttctgat gccggatata
    31921 gtgttcatcc ggttgctgac ggaggctaca acgcctcctg gtgtgttctc tataaagcga
    31981 catagtgttc gccgcttctt ctaattaaag tcccgcgaag atctcaatct ccttgctgtc
    32041 ctctgtcagc tttacgattg ccttctttgt ctttgcagtc tttccgaata ccatgcctct
    32101 tctctttgtc tttccgtcaa ggttcatggt gcttacagct gctacctttg ttcctgggaa
    32161 cattttctca acagcctctt taatcatggt cttgtttgcc tctgtgtgaa ctaagaaagt
    32221 gtatttcttc tcgctcatag cgttcatgct cttctcagtt acaactggct tgaggattac
    32281 atcatagtac tgaatatttg ccattatgcg tacacctcct cgatagaagc tacagcagcc
    32341 ttagttgcta ctactgtgtt gtatttcaga atgtcatata cgttgattgt gtttacgaaa
    32401 gctgtcttaa ctgtaggaat gtttcttgca gataatgcag cgttctcgtc agcgcctact
    32461 accagggcct tctcaacctt taagttcttc ataacctcag caaatttctt tgtcttgatc
    32521 tctgcgaagt ttaactcgtc aactacgatg aacttgttct cgtttactct gcttgtaaga
    32581 gcggatttga gagccagtct cttctccttc ttgtttaagc ggattgtgta atcgcgtggt
    32641 gtcggagcga atactacgcc gccgcctgtc cactgcggag ctcttgttga accctgtctt
    32701 gcgtggcctg ttcccttctg tctccacggt tttcttcctc cgccggaaac ttcggaacgt
    32761 gtcttagcct tctgtgttcc ctgacgcttg ttggctaact gagctacaac agcaaggtga
    32821 accaggtgct cgttcacttc tacgccgaat acagcatcgt ttaactctaa tgtgccaact
    32881 tcgttgcctt caatattgta aacagatacg tttgccatct gtatgttcct cctttcctat
    32941 taagccttac ttacgagctt taacagtctc tttaattgtt actaaggatt tctttggtcc
    33001 tggtacagcg cccttaacaa ggatcaggct gttctcagca tctactctta cgatttccag
    33061 gttctggatt gtaaccttaa cgttacccat gtgtcctggc atgcctttgc ccttaaatac
    33121 gcgtcctggt gttgtagcgg aaccattgga accctggtga cgatggaact tggaaccgtg
    33181 agccataggt cctctgtgct gaccgtgtct cttgatggcg ccctggaatc ctttaccctt
    33241 ggaaacagca gttgcgtcaa tcttgtcgcc tgctgcgaag atgtctgcct taatctcgtc
    33301 ctttacggaa tactcggaag cattctcgaa acggaactct ctgacatatc tcttgtagga
    33361 aactcctgcc ttgtcgaagt gtcccttaac cggctttgtc acaagcttct ctctcttgtc
    33421 aacataacca acctgtactg catcgtaacc gtcgttctct actgtcttaa cctgtgtaac
    33481 tacacatggt ccagcctgaa gaactgttac tggagttaaa actccgtctt cgttgaaaat
    33541 ctgagtcatt ccaacttttg tagctaaaat cgctttcttc attttttgac ctcctgtctt
    33601 tttctacagc ggaacgcggg attttccgcg ttcatcctag aacagtccag aaatctatct
    33661 aaacccttca ggataactga caaatcttat ttgtttttca tcttgatgtt gatgtaaacg
    33721 ccagccggca tttccagtct ggataaagca tccactgtct tctggcttgg tgtgatgatg
    33781 tcgatgagtc tcttgtgagt tctctgctca aactgctctc tggaatcttt gtacttatga
    33841 acagctctta agattgttac aacctctttc ttagttggta acggcaccgg tccgctcacc
    33901 tttgatccgt tcttctttac agtctcaatg atttttgcag cagactggtc aaccagctga
    33961 tgatcataag ctttaagtgt gattctcatt acttgacttg ccataaaaaa agtcgcctcc
    34021 ttttcgtact atttgaagca cgacaagcgg tgactgtaca catatccgtg tgtgtcatac
    34081 aaaactccac actgaatcct ccatatatta ggtattctct aaagttgtac agtgacttgt
    34141 cgccagtttc ctaacttgac attcgctcca cggaaaacct gccatctctc aggcagcaac
    34201 ctcgcgcttc attgctatca tgccacagcc tctgtatcat atcatatgtt tcctgtaatt
    34261 gcaagggatt tttctacttt tttcgccgat ttttccttag aaaatcgcgg cctgtttttg
    34321 acgtttttgt gcagaatgac ggaaccgggt tatggcgcag aaaaagaaat gttttcttgt
    34381 tccatcaaag gcttagtcac cgaaaacatt tctttttctg tagtggaatt tgtaaatagg
    34441 aaaaggctgc aaaattgcga accaggtgac cggctgcgtt ttctgctcga ttcccgcatc
    34501 tgttatccgc cgttcgcgaa aactcgcctt cgtctcagac acttcgctcg gcggcggaaa
    34561 tcagcgcgaa tctcgcagcg aaagcctcgc catcatcacc tggtccagca atttcacgcc
    34621 tcactcaaaa agcacgacat atccgaacac aaaggaacag atgatcgcta tccccccgca
    34681 acttcttgca agaatgaagt aaaattgagt cggggagcca tctttgacat agaggaaatt
    34741 ttctattttc caaaccagat ccggttttgc tatcaaaaaa acgccaatag caaacatgca
    34801 aagcacctgc agtatttcaa tcataatcga atcccccgtt aaattgtcgt tacatgatac
    34861 ctgtccagtc tgctgcttcc tctgaaacta caaaagaaag aagagcaaac tttcctctgt
    34921 ctttatcaga gcagggaaag tcttctcttc ttccttatta taatgcttat ttacttagtc
    34981 ccactctacc ggctcgtatg gatctctcgc atactcgtcg ccgttgtcgg actccttgtc
    35041 tacctttacc acaacgcccg ttttattggt ttcgaacttg gtgccgctgg aatccttgac
    35101 tgtcgtatct tccatcacct ttccggatgt gttgaccaga tagtttctgc cctccacgca
    35161 gattacctcg tacttggttc cgtcgtcagc ctcctgaagc ttgcccttgt agaacaggta
    35221 cttgttcttc acgcctgtaa agccgcgtcc cgcttttccg ccggactctg tgaagtaaaa
    35281 ctcgctcttg gttccgtcgc cttcctcgat ggtcatcttt cccttctgca cagagcttgt
    35341 ctgcctgtcg ccgaagtaat aagtctcgaa gtcgcttcca ttattcaggt tgcggagtcc
    35401 gtaaacagga tttccattct catcaaagag ataggtaatg ccgttgatct tctccagatc
    35461 cttgactgag gcgttctcca ccgacggccc taccttgggt tctccgtcgt ttccgaaata
    35521 gtaccactgc acctcgtcct ccacatcgcc ctcgtagtcc tccggcggat aggtggaata
    35581 ccagcctgtg gtcagctttc cattgtcctg aaggtagcgg taatccttga aattgtcctc
    35641 atcgccgctg acacagatcc atccagtctg catccgtccc tcttcgtcaa agtaatagtt
    35701 tacgccgtca atcttatatt tcttaaagct gtctccgcca gtctccggca cataacgttt
    35761 tccggagctc tggaaatagt accagtggtg atcgtcgtcg tcctcgtagg ggcggacatc
    35821 gtcgtcgtca ttgtcatcgg cgtccggatc ctccagatac tgccagcctg tgcgcatggt
    35881 tccgtcgtct cccagataat agagatcgtc gtcagcccag cctgtctgca tctccccgtc
    35941 tccgttgaaa taataccact tgtcggaaat cttctgccag ctgtcagaag ccgcctttcc
    36001 gtcgcttgtg aagtaatacc acgcctgctc tgcgttattg tcccagccgt cgtccttctt
    36061 cgcaagcttc atacattttc cagccaccat aatgccgttg gcgtctacat agtaatcccc
    36121 gtctacccag gaattcagcg ccatatttcc gttataatcc agatatctcc agagaccgtc
    36181 ggctcccttc tgccattcat tggtcacctt gcgtccgttt gtatcgtaat atacccagtt
    36241 gctgcccgat ttctgccatc ccgaagcgcc aaagcaaacc gccgcgcccg ccatagtcag
    36301 cataatagaa agaaccgctg cggcaatcct ttttctcttc atctatgctc ctcctataaa
    36361 ttccgcttat acttctatgt atcattctaa caagagccgg taaaatattc aagcaaaata
    36421 atctttcaat tctattacga aagaggaaac aaacctttga cacctgtcct gcggccatat
    36481 ataatatcac atgtgaacac agaactatat tatatagaag aaactgctta attattaatt
    36541 attttggttg ctgcaccgcg ccagaccagg gaaggaagac tccttcatct gccggcgccg
    36601 gaatgcagga gaaaggaaca cgatactatg tggatagctg acggctggaa ggattacgaa
    36661 gtattagact gctccagagg agaaaagctg gagcgatggg gaaaatatct gctggtaagg
    36721 ccggatcccc aggttatctg ggatacgccg aagaaaaata aagggtggaa gcgcatgaac
    36781 ggccactacc acagaagctc caagggaggc ggagaatggg agttcttcga tctgccggag
    36841 cagtggagca ttcattataa agagctgact tttaatttga agccgttcag cttcaagcac
    36901 acggggctgt tcccggagca ggccgctaac tgggactggt tcggcgataa aatcagaaag
    36961 gccggacgcc ccattaaggt gctgaacctg ttcgcctaca caggaggcgc cacgctggca
    37021 gccgccaagg ccggcgccca tgtaacccat gtggacgcct ccaagggcat ggtggcctgg
    37081 gctaaggaaa acgcccgctc ctccggcctt tctgaggctc ccatccgctg gattgtagac
    37141 gactgcgtca aattcgtgga acgggaaatc cgccgtggaa atcattacga cggaattatc
    37201 atggatccgc cttcctatgg aagaggcccc aagggagaga tctggaaaat tgaggaatcc
    37261 atccacccgt ttgtacagct gtgcgccaag ctgctgtctg atcagccctt attttacctg
    37321 attaactcct acaccacggg actggctcca gccgtcctca cctacatgct ctccacagag
    37381 ctggttccga agttcggcgg ctctgtccgt tccgaggaaa tcggtcttcc cgtcacagac
    37441 agcggtctgg tgctgccatg cggcgcttcc ggacgctggg aggcataagc gtatccgaat
    37501 catttcacag cgcacttaca aaaaagcccg ttcaggacct ttaaatccct gaacaggctt
    37561 ttctttttct atgctctttt accggcctcc gttgatcaga cgccagaacg gccctgtatg
    37621 ctttttcagg aaggctccca gcttccaggc tgtgatcaca cagacagccg ggattaccag
    37681 gtataccaga agggccgctg ccgccgtatg gggaaggagc attgccgccg ctttgttcat
    37741 tcctctggcc agaataaagt gaattgtata gaggaaaaaa ccgtatttca tccactctct
    37801 ggcctccgga agcctggttc ctgataccgc cgcccagatc gtgacgggaa ccgtaaaacg
    37861 gtacagcacc gtctccagca cagaatgcct gactgtgatt ccctgataaa agtaaacggc
    37921 cagaccgatt cctgccgccg ctgtcagaag gcggagccac ggttccaggc gtctgattcg
    37981 ctctgttctc tccgtctccg tttttttcct gtctgtctgc tcttttttcc agctttcctc
    38041 caccagccag ctgccgtgga gcgctccgta ggccgccgcg ctgtagtaaa acagcgcgtc
    38101 catattgatg acaggaagat tcaccagatt tttaatgcag taaagctcca gcagaagcgc
    38161 cgccagtccg gccaccctgt ttttcagcag gggatagaga accggagaca gggcaatgag
    38221 aaaaatcagc tgatgcatat accagaaaac cggattatag gtaaagtgga gcaccgcctc
    38281 cgccatcacg ggaatgctga attccactgc agttttgtcg gaaagtccgg ccagaaaatg
    38341 aattttccca gccagagcgt aaccggcgta gtagaaaaag ttccacagca ggtagggaat
    38401 cagcatcgtt ctgattcttc tctccatctt cggaaccaca tcctgaaagg agcagttccg
    38461 atagaactgg taagcggaaa tcataaaaaa tcccggcacc gccacaggcc ccagcacgtc
    38521 cgccaggata tgttcaaagg cccacaccgt ccgtcctccc ggagagaagg cgggaagcgt
    38581 cagaaacata tctgcattat agctgtgaat catcaccacc ataaggctga aaaaaaaggc
    38641 ggcaaagcac accttgttgc gaaactgctt ctcactcaaa tttacattct cctctcttgc
    38701 cgccggcacg gctctcttgt ctgcagatat gtctcaaaat cacagccgcc agaaaaaccg
    38761 ccgccccagt ctgaatcagc aaaacccccg gcctgctttc aagccatgtt ccataacgga
    38821 ccgtctccaa gaaaactgcg gcgctgttag cagacgcatg aacgataacg ggaacggcaa
    38881 gcgttctctt tctctcatac agaaaagcca gaagacagcc taaaagtccc gcgtaaatcc
    38941 cctggagaag ctgtccatgg tacaggccga acataagcga ggagagaatc agcgcgcctg
    39001 tacgccccag acgtcttatc tccctcaggc ttccgtacat ggctctgcga aagagaaact
    39061 cttccgcaaa cggaatgatg catccgctgc agagaaaaag cgtcgcaagc gaaaacgccg
    39121 tcccgggcgc agcagctgct gcctttgctc cggcagatat ggcttcagca gacaaagagc
    39181 cggaagatat agttccggaa aaaccttccc tcagcaggaa aatcagcccg ctgcccccca
    39241 ggcagcagca gatgcccaga gcaaccaaag caataagaag caaaaaactg ccgatttcct
    39301 ctctccgcaa atccagacgc cgctccggcg ctttgccttc ttcttcccct ctgccgtact
    39361 gtctccagaa aagtccagaa accgccagtc cggcggccgc gttagcccag agaaccgccg
    39421 cgctcagatt caaagaggcc gccccagtcc agccatccgg agctgccgca aggattcctg
    39481 ccaggccgtg aagcgccagc tctgtaaata ctgcataggc cgccagcggc agaaaagccc
    39541 tgaaaagtag atgtttcttc atcaggcttt ccccgccagc tccatggctt ttcctgcgtc
    39601 cagcattccc gccgtcgtgg tttttccctc catagagctg tttttctctg aggaattcag
    39661 aagaatctcc ctgattttcc ctgtgctcag atccggtctg gccgacttta taagggcagc
    39721 ggttccagac accatgggcg cggccatgga agtcccgctc atataggcgt actggccgcc
    39781 ggaaatggtg ctcaaaatat attttccggg cgcggccaga tccacagagc tccccccgta
    39841 attggagctg ggctccagat ttccgtccag acgcatactg gccacagaaa taatattttc
    39901 caggtcaaag gcagccgggt agacaggctt ctcgtccaga ttgactccct tcccctcttt
    39961 atctccgttt cccgcggcta ccacaaacag catctcggaa tttttcatag tatcgtaaag
    40021 ctcctggtta aatttccccg ttccgaagct gaggttgcag acggacgcgc cctgggcctc
    40081 cgcatagcgg atggccttcg ccacgttttc cggcgttccc acgccgtcct tggttcccag
    40141 cacctttaac ggcataattt tcacataggc tggatcgcag atacctgtaa taccgacgcc
    40201 gtttttccct gccgcgatgg ttcccgccga gtgggttccg tggttgtcct cgcttccctg
    40261 atagagctct cccttcccag aatagaaatt ccatccgtgg acatcgtcca caaagccgtt
    40321 tttatcattg tcaacgccgt ccccggctgt ctctcccggg ttggtccaga tactgttctt
    40381 taaatcttcg tgatccgtct ggacgccggt gtcaatcaca gccaccacca cctgcccctt
    40441 attttccagg gcgtcgtagg ccgttctggc cggcgtcagg ttaatatcca tgcccgccct
    40501 ggcaaaggta gtggcccgcc cctctgtctc aggcccatag tcggagctgt cctggctgtc
    40561 ggacaggtgt cccggcatgg aggaattcat gttctgagtt cccgtcacca ggcggaactg
    40621 gccgttattt agaaaagccc actgatagct gttgtaggga tctccctggc cgtaggcggg
    40681 cgtaccaggc cctgcggcaa aggctgtgcg agagccgtca aagggatttt ggcagaccag
    40741 ggataaggcg gcggctgtca gaactgcggc cgccgtcttc tgcagctttt ttgacggcgt
    40801 cttctccccc tcttttcccg cctttttctc tgttttttta ggagactttt tcccggaacc
    40861 tttttttcca ttcttctctg tctccggatc cttcaggccg ataaagacca caatggtcct
    40921 ggcaggaacc agaaactgct tctgctgttc cagacacggc tccttcccct cctcgtaaat
    40981 gccgtttctg tccttatcgt ccgtattgaa ggccagatgc catttcatgc ctttcgggag
    41041 ctttggaagg gcaaattcat ggggctccca gtgcatgttg taggctgtga agaagaaatc
    41101 gtcgctgctt ccgtccggcc tcttcgcata atcgccgcag tacatgattc ccagctgtct
    41161 gcggaaattc tcaaactccg gacaccaggc cttgactcca tggtaggaga cgtccgggtg
    41221 gccgcagacc aggtaatcca tgcccatggg ctcctgaggc atatggaaca ccgggtgttt
    41281 ctttctgaat gcaatgacct gctttgtgaa ctggaacaag tcccgatttg tctccagaag
    41341 ccgccagtcc agccaggaaa cggcgttatc ctggcagtag gaattattat ttcctccctt
    41401 tgtagcgccg aattcatctc ccgccagaag gagaggcgtg ccctggctta aaaacagaat
    41461 cagaagagcg ttccgaatct gcttctgccg catgccgaca atcttctttt tgcggcttgg
    41521 tccttccacg ccgcagttcc aggtgtagtt ccaggcgctt ccgtcctgat tgttctcccc
    41581 gttggcctcg ttatgcttca tctcatagga gacggaatct gccagggtaa agccgtttga
    41641 atgggccatg tagttgatca cgcccatatt cctgggattt ctcctgctcc tgaaaatcag
    41701 gccgttcatc tgatcctcgt ctccctttaa aagacgcctc atgtccacca gaaaaccgtc
    41761 gttgtactcc gccagatggc ggctcttctc ctgttttccc ttctcagagc cactctcctc
    41821 ccagaaggag gcgaacagct ttgtcctgga aagccaggga tcgtctgcca gagacgggca
    41881 ggaggcgatt cccgtcaggt gtatgccgtc cacatggtat tcccgcaccc agaaccgcac
    41941 tgcctcgctg ataaaggcag cgctttcctt tccggtaaaa tacagttcaa taatcagctc
    42001 caggccgttt ttgtgaagct cctttacaag agccttgaat tcagaggagg gattcttttt
    42061 tcccggcttt ccctccgaat aggaggcctt gggggcaaac agaagactcg ggccgtagcc
    42121 ccagtagttg agcttccccg taggctcgtc ggggccgtag ggattgccgt ccgagctgtc
    42181 cggcatcatg acctcctcaa actcattggg aggcatcagc tccagggagg tgacgcccag
    42241 ctccctgaaa tacgggattt tgtctctgat tgcctgaaag gttcccggcc gtcccgccgt
    42301 cttgtccttc cgatccgttc ccctcggccc catggtaagg cccctcgcgt ggatcctgta
    42361 taaaatcata tcctcatagg gaatatgaag aggctcgtcg ccctcccagt caaaataggg
    42421 aagctcaaag ggggatctca gcggattttt cacatgggac agctctcccc aggtctcccg
    42481 gcccgtaaaa gcgtgtccaa agggatcggg ctgctctgtc ccgtcgcaga tcagggaata
    42541 ggaaagccct gcaaaatctc cgcccagcag gcggattgtc cgcatatttc caagtcttga
    42601 accttcggga aaaggaaaaa tcctctgttt ttcctcccct cccgacgttt caaatacagc
    42661 caggcttacg ttctccccct ccgccatggt gcagatgtgg aagccgcctt ctgtcttgac
    42721 ggctccgggc ggaaaatatc ccggcatgcc ttctgccgca gcaagttttt ctatcttcat
    42781 gttgcactct cccatcccgt cctaacggcc gttctgctcc gctatccgct ccgccagatc
    42841 attcagatac atccagcgct ccattttctc ctccagaagc gcctccgtct cctccttctc
    42901 cttcatcagc gcagccagtt tttcgtagtc tctggcagcc ttattgatct ccggccccag
    42961 ggcctctgcc ttctcctcca gcgccgcgat atcgtcctca atggtttccc attccttctg
    43021 ctccttgtag gtgaatttca gctttttcac ctggccgtcc ttccagctct tcctggtgtt
    43081 tttctcaggc cccccctcca tctccttttc cacggctgtt cctgcagacg gactgttaag
    43141 actctctccg gcagcctctt cctcctgcct tgcggcctga taatcggtaa aaccgccctc
    43201 atactggcgc agccttccat taccctcaaa ggcaaaaatc cggcgcaccg cccggtccag
    43261 aaaataccgg tcgtgggata cggtgatgac aatgccctgg aagctgtcca ggtagtcctc
    43321 cagaatcgtc agggttctga tgtccagatc attggtaggc tcgtccagaa tcagcacatt
    43381 aggggcctcc atcagaatgc gcagaagata aagccgccgt ttctcgcctc cagacagctt
    43441 tccgatgacc gtgtactgca cagaggacgg aaacaggaac cgctccagca tctgggaagc
    43501 ggaaatgctt ccctccggcg tcttcacata ctccgccgct tccttaatgt agtcgatgac
    43561 gcgcagcgaa tcgtccatcg cctcgttctc ctgggagaaa tatcccagct gcacagtctg
    43621 tccaatctca atctccccgg aatccggctg cacccatccg gcaatcatct tcatcagagt
    43681 cgactttccg ctgccgttct gcccgataaa gcccactctg tcatttttca ggaaaatata
    43741 gctgaaatcc tgaatcagaa ccttgtctcc gtaggctttg cagatatgct tcagctcaat
    43801 ggtcgtccgg cccagacggc tggagacaga gcccagctcc acctccccgt cgtactcagg
    43861 cccctttctg gcgctcagct cctcgaaccg ctggatcctg cccttctgct tggtagagcg
    43921 cgctctggcg ccccgcttca tccactccag ctccaccctt aaaatagact ggcgtttccg
    43981 ctctgacgcc tcctccatgg ccatccgctc cgccttcagc tccagaaagc cctgataatt
    44041 cgtctgatag ctgtagagct ttcccttgtc aagctccaca atcctgtttg tcacgctgtc
    44101 caggaaatac cggtcgtggg tgatcatcac cagcgctccc ctgaatttct tcaggtactc
    44161 ctccagccag tcggccatgc cgctgtccag atggttggtc ggctcgtcta acaccagcag
    44221 atccgcggtg gagagaagga cgctggccag agcggctctc tttctctgac cgccggacag
    44281 cgtctctatc ttctcattcc agtctggaat ccccagcgtc atcagcatgg ttttcgcctg
    44341 tccttccaga tcccagacct gttcatggcc ctgattttcc cggattacac tctctaacac
    44401 cgtgtatcca ggctcaaata ccgggttctg gggcaggtag cggatgtaga gatttctccc
    44461 cttcaccacg cttccttcat ccggctcctc caggcccgcc aggatccgaa gaagcgtaga
    44521 ctttccagtt ccgttaatgc cgattacccc gattttctcg ccttcgttga cagaaaaagc
    44581 cgtgtcgtca aacagcagcc gctctgtata agatttcgta agatgttcaa tggtcaataa
    44641 attcatatct gttctcctgc ttccgttcca gcctactgaa tcaccagttc aaccggacag
    44701 tgatcggatc ccataatctc cgagtggata gacgcgctta ccagccggtc cttcaagctt
    44761 tctgatacgc agaagtagtc gattcgccat cctgcgttct tctctctggc cttaaatcgg
    44821 taggaccacc aggaatatgc cccttctgtg tccgggtaaa aatgacggta ggtgtcgata
    44881 aatcccgcgt ctaaaagctc tgaaaatttc cctctctcct cgtcggtaaa gcccgcgttc
    44941 tttctgttgg tcctgggatt tttcaggtca atctcccggt gggccacatt caggtctccg
    45001 cagaaaatca ccggcttttt ctcctccagc tttttaagat aagagcggaa cgcgtcctcc
    45061 cactccatcc ggtagggcag gcgggccagc tcgttctggg aattgggcgt atagcaggtc
    45121 accacatagt aatcttcgta ctccgccgca atcacccgtc cctcgtggtc gtggacgtcg
    45181 attcccagac catataccac gcttaaaggc tcctctttag taaacagggc ggttccagaa
    45241 tatcccttct tgtccgcgta gctccaatac tgatagtagc ctggtatatc aaggtcaatc
    45301 tgtccggcct gaagcttgct ctcctgaatg cagaaaatgt cggcgtcaag ctcttgaaac
    45361 acgtcgagaa atccttttcc cacacaggcc cgcaggccgt ttacattcca tgaaatcatt
    45421 tttttcattc tgttttgtct cctgactagc ctcccgcccc ttcccagggg caggaaagcg
    45481 atgatactgt cagtatacca ttttcttgat tattttggaa gagagcagag aaagagtcac
    45541 cggaaaagca cagatgataa gaatttttag taaaatttaa ggttcttctc tccgcagaaa
    45601 tttttcagat tgtagagaat cagaaattca ttgatttccc gctgtgatat gtagtcctcc
    45661 aggctgcccc ggtaataccg gaggtcaatg aggtgaatgg attcgcagtc tccaataagg
    45721 aagggaacca gggcatttgc aaaggaatcc tttactatca gcagacgcct gccgtttttg
    45781 ttggaggtct caatggtcac ctccgggtgg tttccattta aaaaaatctg gtactgatcc
    45841 tttttcttca ggttttccgg ggcgtagacg ctgtcagaaa tctccctgcc aaaattgtag
    45901 gaaacggtat aggatggctc ctgttcccgc gtaaacagct cgatggaatc tctgcttccc
    45961 tctgcctcca aaaccttgga gtccagagaa ccctgaaagg agtctgagac ctgcactgga
    46021 tggaactggc tggcaggcag atacattcca tttgcctcgc accacttcag atacccctga
    46081 aaggctcccc tgctggtcca gtggtgatcc gtcttataaa aaacgccgtc ctcccggtgg
    46141 gcagaaagcg tctggcgcag gtcaatcagc gtcccggagg acagcccctt ttctatctgg
    46201 gccatagcct tctcctggca gaaggacggc gcgtgaggcg gcagcttgtc cttcatggtt
    46261 tccgccgctg tcggcacaat cataacgaaa gccttcttat cctgatgttt ctccaaaaag
    46321 ccgttcagcg cttctatgtt attctgaagc cgttcttcgt caaaatcctg ttccagccac
    46381 tgttctatca gatatccgtc tttccccaga tacacgccgt tgatctcccg gctgcccgca
    46441 gcctttaaaa gctctgtcct ggctgtggtc agactgtcgc gaagcgggag ctgatcgctt
    46501 acatattctt ccatatcccg cataaactcc cctgttttta tacgttccag agaaatatag
    46561 ggcttctggg ccagatacct gttttcattt tctgaaaact cccgatcctt taatgtaaaa
    46621 gtaaacgccg gcgccgcccc gatcacagcc agaaaaccag cgattcctag aaaatttctc
    46681 catttcttcc tgtctctgtt cttatgttct gtcataacac tcccaccact tctcctgtcc
    46741 gtcatttcgc cttaattcct ctctgtcttc ctgcacccta aaaccgaaaa tacaaaaacg
    46801 ggttgtaggt tcctcctgcc agaaaacaga tgctggccgc aaaaagaacg ggcagaaagg
    46861 cccgcttcat tttaaaaatt cccagactgc acagggcgca gacaacaaag aaaacgcccc
    46921 aggtctctcc atagtaaagg gccgcttccc ctatccatcc gccgcttccc aggccgaaca
    46981 tggactttac ataagtacat acgtccgcca tgctgtcaaa ggcaaaaatc acccagctga
    47041 ccgccacgaa aatcaggcag taggcgtggg aaacccaccc tggaagcgct tccagacgcc
    47101 ggagcaaaaa cagcttttcc gctgttaaaa acaccccgaa gtacagcccc cagacaagaa
    47161 agttccagct ggctccatgc cagagtcccg tcagacacca gacaatcagg aggttaagca
    47221 gctgtctttt catccccttc ctgctgcctc ccagaggaat atagacgtat tcccggaacc
    47281 aggttcccag agaaatatgc catctgcgcc agaattccgt catgcttttc gaccggtagg
    47341 gatggttgaa attttcctga aaatgaaagc cgaacagctc tcccagcccg atggccatat
    47401 ctgagtaccc ggaaaaatcg aaataaatct ggaatgaaaa ggcggccgcg ccgatccagg
    47461 cttccgcagc ggaaagcccg gccagatttc cgccggaaat ctgttcccac accatgccga
    47521 tattgttggc caggagaacc ttcttggaaa gtcctgtaat aaaacggctg attccgtagg
    47581 aaaatctctc tgccgtcacg tttctgtctg ccagctggcc gctgatatcc ttatacttga
    47641 caatcggccc tgccaccagc tgggggaaca tggccacata ggccccgaac tgaaccagat
    47701 tcttctgcgc cccggcctgc cccagataca cgtcgatggt gtaggacatg gtctgaaagg
    47761 tgtagaagga aatgccgata ggaagggaca gttccaaaag aggaaaatcc gtccctccag
    47821 ccgcattgat tatctcaata aaaaaattgc tgtatttaaa aaatcccaga atccccaggt
    47881 tgccggccac tgagagaagc agcacagccc tggcagccct ttttctgccg gaggacaggc
    47941 atttctcaat ggccagtccg tttccataat caaatatagt ggaaaacagc ataatggaaa
    48001 cgtacaccgg ctctccccag gaatagaacg ccagactcat taccagaagc accaggtttc
    48061 tgagccgcga agggcctgcg taatagagca gaagcgtcaa agggagaaag taaaagataa
    48121 ataaaatgct gctgaaaacc atgcctgctc cctctactga aacagctccg caagcagctc
    48181 ctccgccttt ctgccgtcat cgcagacgca gacagccaga aaacggccgt actgcttcac
    48241 caccgctccg tccaggcgct ttacctcctt tggcacatag gaagcgaagg cctctttctg
    48301 atcctcgatc ctctgctctg ccagggaaac cgcctctttg cagtcctctt ccgtctcaaa
    48361 ctcgaacacc gcaatctctt ctgccgtggc tccgctgctg atgtagacag aggactgtac
    48421 cgccgcatca atgccgtaca gcatccccgc catgtcctca tccgccagag tcagctcgtc
    48481 ctcaaaggcc agatcttctg ccagcttctt tccaatttct ccggcgtcag cctgctttcc
    48541 cgtctggctt tccgtctgct ttcccgcccc ggcctgcccg ttctgtccgc cgcatgcaga
    48601 cagaacggcg caggacgcca gaatcagccc tgctgtgatt ccctttttct gtaagctttt
    48661 catccatgtt ttgtttttca tttcctttct cccttctgtg tgctgtatcg cgcggccgct
    48721 gctctctgcc gtcctgtcag tgcgcagcag ctgtgtggct ttttaaatag tccagccatt
    48781 ttttgcagta atcctttttc aggtgaatgc cgtcaaaggc cgcatcggct ggaaggcttc
    48841 cgtcagaggc ggctaccgca gacgctgtgt caataaagta cacctgcttt tcctgggcca
    48901 tctggcgcag cagtctgtta aattccgcaa tctttccatt cctgatatag ctgtgggtgg
    48961 cagacacctg attcgtcacc ggcataatct cctgaacgta aatgactgcg tctggattta
    49021 tttcccggac agcgtcgata atttcctcat atttatgaat gaaaacatca ttgtagggcc
    49081 agccgttctc attgatccca aacataatgt aaatcttgga aaaggaggtg gttttcaggg
    49141 cgtccatcac agagaccctg ttctcccctc tgcggatcac cggcttggtg aacacagtat
    49201 ccaccatcag gcccttatag gtgtaggcag tcgtattgga cagccccgtg ttggtaatca
    49261 ggccctctgt cctggaatct ccgataaaca cggcgtcgtc aaaatagctg ttatccactg
    49321 gctctgaaag gggaacaggg cgggaaaaat cataggcccc ggcctccgcc tcggccgtca
    49381 tctcttccac cgccatcttt tccgccctcg tctcttccgt ttccgtctct tccgcttccg
    49441 tctcaggcag ggattcctcc gatccctcca aagccggttc cgtctccgtc tctccccaga
    49501 tcagcccggc ttccgctccg tttctttcgg caaaaacgtc tgacaggcgg cccgcttttc
    49561 cctgatttcc aaatacaggc agataattca ggactgaaat caaaatcagg cacagaacga
    49621 ttccctccag cgaggacacg atgctccgaa tccgtcggcg gcgtttttcc ttcctccgct
    49681 ttatcctctg acgttctctg taatattccc gatctcttct ggttaaatta tcattatccc
    49741 atcggtctgc ccgacgctgt tcctgatacc tggcccgctg catctgtctc ctccgtccta
    49801 cgaagcctgc cgttctcccg tccgtttgca tccgctttcg ccctggcagg ttttaatcct
    49861 ttcttctgtt tctattatta gacggaaaaa aacgccaaaa agttggcgca actgaaattt
    49921 ttttattctc tgccccggga tacctgaaaa tggctccgcc tttcccatcc cccatctgga
    49981 aaacgctcgt ttttgactgg atttgactct ttgtgaaaat accacaaatt tattctctat
    50041 attttgtgac ttattttgat tgattatgac tgtttgtggt tgtataataa ggctaacaaa
    50101 tacagcagga ggtttgaaac gtgatttata ccgttacttt taatccgtct ctggactaca
    50161 tcgtaactgt cgaccagttt gcatttggaa agaccaaccg cacatcctct gagcagctgc
    50221 ttcccggagg caagggcgtg aacgtgtcta ctgttcttca cagtctggga atcgaaaaca
    50281 ccgctctggg atttctggcc ggatttacag gacgtgagat tgaagaaaaa atccgccgca
    50341 gcggcgtaac ctgtgatttc attttcctga aacacggctg ttcccgcatt aatataaaaa
    50401 tgaaggattt tgacgggact gagatcaacg gcgcggggcc ggagattgac tatgcttccc
    50461 tggagcagct gatgagccgg ctgaacagtc tgaaaaaggg cgataccctg gttttagcag
    50521 gcagcatacc tgcctccatg ccagaggaca gttacagccg gattctggaa atgttaaaag
    50581 atcgcggagt gctcttcgcc gtagacgcca caggcgatct tctgatgaac gtcctcccct
    50641 accggccatt tctcattaag cctaacaacc acgagctggg agagattttc ggagttgagc
    50701 tgaacagccg ggaggaagtg gttccctacg ggaaaaagct gcaggaaaag ggggccagaa
    50761 acgtgctgat ttccatggcc ggacaggggg ctgtgctctt agacgaggaa ggcggcgtcc
    50821 acatgcttcc agctcccagg ggcactttag taaacgccgt aggcgcaggc gattccatgg
    50881 tagcgggctt tttagccgga tggatggaaa agcatgatta ctcccacgca ttccgtatgg
    50941 gggtagcggc aggaagcgcc agcgcgttct cgaaattctt ggccacagaa caagaaatac
    51001 gcagcattta caggacgctt aacggcgcgt ctgactcata aatcgcagga aacaggatga
    51061 aaaggaggga atctcatgcg gattacagat ttgattgata agcggagtat ctgtcttgac
    51121 ggaaccccgc gcacaaaggc ggaagccctg gatcagatgg tggccctgat gacggccagc
    51181 ggaaaaatcg cagatgagga gggctacaga aaacaggttt atttcagaga agaggaaagt
    51241 accacaggca ttggaggcgg aattgccatt ccccacggaa aatgctccgc agtccgcgaa
    51301 cctgggctgg ccgctatggt tgtcagggac ggcgtggaat ttgaatccct ggacggtatg
    51361 ccggctcatc tgattttcct gatcgccgcg ccggacacag aggacaacat tcatctggac
    51421 gtgctcagca agctgtctgt gctgctgatg gaccagagct ttgtggagaa gcttacaaag
    51481 gccgagacgg cggaagaatt tttagctgtc attgaccagg cagatcagga aaaaccagac
    51541 attgacagcc agctggccgc tcagaatggg gagcaggaaa acagcccttc tgtttctgaa
    51601 gaggcagaag cttccaaagc caaagcctcc tgccgcattc tggcagtcac ctcctgcccc
    51661 accggcattg cccacaccta tatggccgca gagggactgg aaaaggccgc ccgggccgcc
    51721 ggatgctctc tgaaggtgga aaccagaggt tccggaggag cgaaaaacgt cctcacagag
    51781 caggaaatcg cagaagccgg ctgcattatc gtggccgccg atgccaaggt gcctatggac
    51841 cggttccacg gcaaaaaact catcgaatgt cctgtctccg atggaatcag caaagcggag
    51901 cagctgatcg agcgggccat gaagggagac gcgcctgtgt accaggctgg aaagcctgag
    51961 gccgcgaagg aaacaaaagc ctctggaggc gcagcccaca aaatttacac tcagctgatg
    52021 aacggcgttt cccatatgct tcctttcgtc gtaggaggcg gaattctcat cgcccttgcc
    52081 ttcctcatcg acggcctgag catggatatc aactccctgt cagacgaagc cagatctgct
    52141 tttggaacca tcaccccggc agccgcggcc ctgaaaggaa tcggcggaat tgccttcggc
    52201 ttcatgctcc caatcctggc cggatttatc gccatgagca ttggagacag accggccctg
    52261 gccgtaggat ttgtaggcgg aatgatcgcc gccggcggaa agtccggatt cctgggcgct
    52321 ctactggccg gatttatcgc aggatacctg gttctcttcc ttggaaagct gttcagccgt
    52381 ctgccggaag ctctggaaaa aatcgctcca gtgctcttat atcctgtatt tggaatcctt
    52441 ctcattggtt taattatgac ctttatcatc gaacctccgg taggattttt aaatacctct
    52501 ctgaacgctg ccctcgcagg catgagcgga accagcaaaa ttctcctggg aatcgtcgtg
    52561 gcaggcatga tggccgtcga tatgggcggt cccttcaata aggcagccta tgtctttgga
    52621 actgcctcta tcgcagccgg aaactatgat attatggcag ccgttatgat tggcggaatg
    52681 gttcctccct gcgccatcgc cctggctacc ctgctcttta aaaacaaatt cacaaaggaa
    52741 gagcgggaat ccggcccggt caactttatt atgggtctgg ccttcatcac agagggagcg
    52801 attccatttg cggcctctga tccccttcat gtgcttcctg cctgcgtcgt cggcgctgga
    52861 gtctccggcg ccctgtccat ggccttcgga tgtactctca tggctcccca cggcggaatc
    52921 ttcgtattcc cggttgtagg aaacgctatg atgtacctgg ccgccctggt cattggaacc
    52981 ctgatcggag ccttcctgtt aggagcgctg aagaagaaaa cggcggaaaa ataaatagaa
    53041 agcacgagga aaattttctt atttcactta aagttaccga aaatttttcc tcgtgcttat
    53101 tttttgttat ttttttggta cttccaggag tagcgcctcc gcctgttttg ttgtaaaata
    53161 tcaataatta tttcatttgc cagagaaagg aaggacgagg aaaatgctta cggaaaagcg
    53221 gcaggaagag attttaaagc tgttaaacgc ccagggcagt gtgacggtgc aggacttgaa
    53281 ggagcggttt gacgcctcgg agtctaccat ccgccgggat ttaacggttc ttcacaagaa
    53341 aggcgcactg atcaaggtgt tcggcggggc ggttcaggca gatctggcta ttgacgctgc
    53401 cgacgcccag gtatccctgc gccagaaaca gcacatggaa gaaaaaatca ggattgcccg
    53461 gtacgccgcc tccttaatta agcctgacga cttcgtctat ctggacgccg gaaccaccac
    53521 gggggccatg attcccttta tcgaggagaa gtctgccttc tttgtgacga acgcagtgtc
    53581 ccacggactg cgcctggtgg agcggggctt ccgggcagcc gttctgggag gagaaatcaa
    53641 ggcctccaca gaggctgtgg tgggaaacga ggcctatctg agcctgaaaa aataccattt
    53701 cacaaaagga ttctggggaa ccaacggggt cagccgcatt tccggcttca ctaccccgga
    53761 tcccaacgag gcgctgatca aggaatttgc catggaacgg accagagaac cctatgtgct
    53821 ctgcgactcc agcaaatttt tccagaccag ccccgtcagc ttcggcgaat tttcctctgc
    53881 cacgattatc acggatcgcc ttccccagga aagctaccgg agagaggaca atattgtgat
    53941 cgccaaggag ccgcctgccc tgtaggtatt cttacctatg gggcggcggc tcctgtcaga
    54001 tcaccgggcc ttactgctcc ttcttctgcc ctgccatgcg gatgatgtac cttccggctg
    54061 atatgagaag aggaagtgta agaagaatcc agactgcctt ctgatgcagg accgcccaca
    54121 gccagttaca cagctctgtc attccatggg tatttatcaa tctttctaaa ataaaaattc
    54181 caaactgtat gagacaaaat aacagaactg cagccacata ctctatagca gtaaatttcc
    54241 tgattataag aaaaattcct gttataatga caaacagata gcaggaagcg atgaacagat
    54301 tccctaacat acctgcctgt cccatgatcg tctccgcttt ctccctcatc tcccactttt
    54361 cagggctgtt aagcatatct cccccagcta ataaaagccc catcccatgg cacagcagat
    54421 aaaccgttat gaaatgaagc gccagggaga aagccgaaaa cagaacggca taccgtatcg
    54481 catatttatt aaccttcctt cttttcattt gtactcccct ctataaaaca caggcgcagc
    54541 cggatttttc cacgctgcgc ccataacctc ttctgtctta ttttattttt acaattccac
    54601 ttccagcttc tgtttctcta tcttatgcct ctcagcgtat ccagtcagca tcagcgtcag
    54661 ggcaccgtct cccgtcacgt tgcaggcagt tccgaagctg tcctgcagag cgaaaatggt
    54721 aagcatcagg gccgttccca tctcgtcgaa gcccagcacg cctgtaatca gtcccaggga
    54781 cgccatgacg gttccccccg gaacgccggg cgcgcctact gcgaacactc ccaacagcac
    54841 gcagaacagg gtcatagtcg gaagatccgg aagagttccg tacagaatct tcgacactac
    54901 catgacgaaa aatacttctg tcagcacaga gccgcacaga tggatattgg caaacagggg
    54961 aattccaaat tctaccatat catccctgag cgtgggctcg gactttttcg cacagtctaa
    55021 ggccactgcc agagtcgccg cggaggacat ggttcccact gccgtcaggt aggccggacc
    55081 gtagttttta agcaccttaa agggattctt tcctgagtac agccccgcca ggccgtagag
    55141 cagagccatc cagatataat ggcctgccat aacgatcagg attacctgga taaatacagg
    55201 aacctgtttt gtaatggagc cttcataagc cagggaacag aacgtcatgg caatgtagac
    55261 cggaaggata ggaatgataa ccttctttac aatgtctaac acaatccgct gaaattcatc
    55321 cagaattcct gttatctgct tcgccttcgt ccatgcggcc gccagaccaa tgagaacaga
    55381 aaatacaagg gcgctcatca cccccataat cggaggaatg gacagctgaa acactacctc
    55441 gggaagctct ttcagcccct ccacgtttgc attaatcgac agggacggaa tgattccaaa
    55501 acctgccatc atggaaaaca gtgctgcgcc cagtgaggag gcgtaggcaa ttccaagagc
    55561 gattcccagc atcctggaag cattatttcc cagcttcgtg atggacgggg caataaaacc
    55621 gataataatt aacggcacgc agaaattgat aaactgtccc atcacatagt tcagggtaac
    55681 aactacattc atcacccctt ctcctgcgta aagaccggct ataattccgg ccgccactcc
    55741 aatcaggaga cggaatggaa gactgcctgt cagctttttc ataaattctc ctttctttct
    55801 cccggattaa ggctgaatct aagcccccct tcagccggcc ggggagaaat acagattttc
    55861 attttctctt acagataaga tatgctccct ctccctcttt tctgtctctt atttcgcttc
    55921 ggattctccg ctctctagtc ttcccacagc tttttcggat aatacccgct gtcctttaag
    55981 ccctggatgg catccatgac catgggcttg tcttccttgt aagtaacgcc gtaccacttg
    56041 tctgcgctct ttaacacagt cacctgggcc ttgtcctcct tcagaagctc gtctacgaca
    56101 aaaggcagga agtattcgca tttttccgga ttgaccggca ggttctgatc taaaaataca
    56161 gtaaaccgct tctccagctc ctcgagaatg ctggaggtaa agccccacat attcatggat
    56221 accagggtat cctccggcag atacgtccag gaagcgccgt tgtcctctgt gtactccgcc
    56281 ttatcgccgt gcttttccac tctggtgcgc tcgtgaatgt cagccagata accgtgttcg
    56341 tccgccacgc acacgccccg ggacacatgg ccgttctccg tcagggtatt gtaaagctta
    56401 tagcctacca tggcgtactg atacctatcg ttgtcctctg tctcgcagag atggaggtaa
    56461 agctccttaa aggccgcctt tccgtagtaa tcgtccgcat tgatcacagc gaagggaccg
    56521 tcaatcacat ccttgcagca gaggatagca tgtcctgttc cccacggctt taccctgttt
    56581 tccggaacct gatagccctc aggaagaagg tcgttttcct ggtacacata ctctacctgg
    56641 atgtgctttt ccatcctgtt tccgatgtgc tccctgaaat ccttctcaat ggccttctta
    56701 atgatgaaaa ccaccttctc aaagcccgcc tccttcgcat cgaaaatgga gaagtcaata
    56761 atcaggtctc catcgtgatc caccggatca atctgcttta atccgccgta gcggctgccc
    56821 attcccgccg ccataattac cagtaccggc tttttctcca tgttctaatc ccctttccgg
    56881 ctcaggcgcc ctgccgggcc cgttcatgcc cggccacaga caccgcttcc atcatttagt
    56941 cctcgttctc ctcagtctct gtcagagtaa atacctgacg ctttctggcc atctcgtcgc
    57001 ttgccaggta ctcgtcgtag gttgtaatct tgtcaatgag cttgccgttt acgatctcca
    57061 taatacggtt ggctgtcgtc tccacgatct gatggtcacg ggaggagaaa ataatcacgc
    57121 ccgggaactt ggtcataccg ttgtttaacg cagtgatgga ctccatatcc aggtggtctg
    57181 tcggctcgtc gaacatcaga acattagctc cggaaatcat catcttggaa agcatgcagc
    57241 gcaccttctc gcctccggag agcactctca ccttcttcac gccgtcctcg cctgcaaaca
    57301 gcatacggcc caggaagccg cggacatagg tcacatcctt caccggggaa tactgagtca
    57361 gccagtctac gataatatcg tcgttgtcaa actctgcgct gttgtccttg gggaaatatg
    57421 cctgcgtggt ggtaacgccc cacttgtagc ttccctcgtc cggctccatc tcgcctgcca
    57481 gaatcttgaa gagaaccgtc ttggcctgct cgttcggtcc taccagagcc accttgtcct
    57541 cacggtttaa gatgaaggaa atattatcca gaacctttac gccgtcaata gtcttggaca
    57601 ggttctcaac agacagaacc tcgtttccaa tctctctctc cgggcggaag tcaatgtacg
    57661 gatatttacg gctggacggg cggatctcat ccagctgaat cttctccaga gccttctttc
    57721 tggaggtagc ctgcttggac ttggaagcgt tggcggagaa tcgctgaatg aactcctgca
    57781 gctccttgat cttctcctct ttcttcttat tggcctcctt catctgcttg atcatcagct
    57841 ggctggactc gtaccagaag tcgtagtttc cagcgtaaag ctgaatcttt ccatagtcaa
    57901 tgtccgcaat ctgggtgcag accttattta agaagtaacg gtcgtgggat accacgataa
    57961 ctgtgttctc gaagttgatt aagaactcct ccagccatgc aatagcgtcc agatccaggt
    58021 ggttggtcgg ctcgtccagc agaagaatgt caggatttcc aaacagagcc tgggctaaca
    58081 gcaccttcac cttctgagcg cctgtcaggt cgcctaccag ctgataatga agctctgtct
    58141 cgattcccag accgtttaac aggttagccg cgtcggactc tgcctcccag ccgttcatgg
    58201 tggcgaactc accctccagc tctgcggcct tcacgccgtc ctcctcagag aaatcctcct
    58261 tcatgtaaat ggcttccttc tccttcataa tctggtacag acgggcattt cccataataa
    58321 ctgtgtccag aaccggatac tggtcgtact taaagtgatc ctgctgtaag aaggagagac
    58381 gctgtcctgg agtgataatc acgtctccgt tggtcggctc cagctggccg gaaagaatct
    58441 ttaagaaagt agactttcct gctccgttgg ctccgatcag accgtagcag ttgccttcca
    58501 cgaatttaat atttacatcc tcaaacagtg ccttttttcc tacgcgtaat gttacattgc
    58561 ttgcgctaat catggttgtt tcctttcttt atatacatta tttatgattt caaagtttcc
    58621 ttttgacaga gtatcagctc cttgcagaga accgcttctg cccctgcaga tctgaaccgg
    58681 cacgccgtgc ctcttctgag gaaaaacgcg ccccttcata ccagactccg cctattttat
    58741 tgtacaggaa aatccatatt ttgcaagagg aaccgagaaa aaagcagggc aaaatgcagt
    58801 tcctctgatc tgttatgcac gagaaaaaag aatgtttttc actcaatttt ctttgcacga
    58861 cagctcctcc accgacagcc tcagcacctg gacccgcgcc gctgcctccg gcttaaattc
    58921 ccagtcttct cgtccgtcac ttccctgtct cttcttctca tgtgtttcac tccttaaccc
    58981 tcagtccggc tgtaaaaaag cttttatttt aatattcagc cctctccagc tccagaagcg
    59041 ccttcttcgt ctcgattcct cctccaaatc cggtcagact gccgtctgct cccacaaccc
    59101 ggtggcaggg aatgatgatt ccaatggggt tatgccccac tgcgccgccg accgcctggg
    59161 cggacatatg ggggcggccc tcctcctctg ccagcttttt tgcaatgctt ccgtaggtga
    59221 cggtcgttcc gcagggaatt ctcagcagct cttcccacac ccggcggcgg aaagggcttc
    59281 cctccggttt aagagggggc agaaaatcag gacttttgcc tgaaaaatag cagtccagcc
    59341 agcgcgcggc ctgaaggagc ggggcaggaa gcagctcccg gccttcgccg ccctctctgt
    59401 tcccagaata accaggcaga accgtcagct gacagcgttc tggaagggaa aacggatacc
    59461 gcttctgttc aaactccagg gaaagaaggg cttcgctgtc ggaaatcaga gtcagcgctc
    59521 cgatgggaga actgtactcc atctgataaa gccttcttcc ggctgtttct gttccagcct
    59581 cctccccgct tcccgtacgt ctcttctttt ttgaattctt ctccatttcc cttcctcctg
    59641 ccgcctcttt ggcctttctg aagccttctg tcctcctcgt cttattttcc agacgtttct
    59701 cttccgtctg cctgctttaa atgcaatttt ggggcgtatt ttcttttcat acctcccccc
    59761 atgtatatag cttttctctc ccgcttttca agatacatat tttcatctgc acggtgcatc
    59821 agcacatgat agttctttcc atcaaccgga taaatagcac aaccgatgga aaattctacc
    59881 aattccgccg ttccgttatc cataaatgct tcgcctcgtt tctctttcag cgcgccgcac
    59941 actgcgtcga cacgttctct ggaatcgtat ccatagagga aaacgataaa ttcgtcgcct
    60001 cccagacggg cacatacaga gccagagccc gccgtatctt tgataatggc cccaatccgc
    60061 ttcaggtatt cgtctcctac ggaatgtccg tacatatcgt taatccgctt cagaccgtcg
    60121 gcgtccatca taatgatcat tccccagccc agatcctgcg tccctttaaa cagttcgtcc
    60181 atccggttgt taaatccccg cctgttgtaa aggccggtca ggttgtcatg gctgctctgc
    60241 tctctcagct cgttgagctc cttccaccac tgggacagat cagacacata gtaggttgcg
    60301 ctctgctcat ccgtctgttt ttcaattttc agataaattt tatcgccgtc tctgtcatat
    60361 tcatagatct gctcgtcctc gtccactgga tgctccatgg cctcttccag ccgtttttcc
    60421 gcctcagaca ccgccagtaa actgtcctgt ccgctttcct ctatgcccag catctccagc
    60481 agacggctgt tgataaacga ttttccaaaa aactggttct tttcaaagat tccaatagga
    60541 atccgccctt tgtccacaat ccgcgtcagc ttgtcccagc ccaggcggat gcctttcaac
    60601 atctgattca tataaaaaat caattcgtta aattcttcca catccgtctt cacagagata
    60661 tctctgaaat cgccctgctc cacctttttc agctcgtcca caatcgccac caggtttctg
    60721 gccagctttt tgtccatata ccaggtaatg cctccgatca ctgccacagc ggtcagaaca
    60781 agataaagaa aaaccatcag tgtggacatc actatgctgc gaagggggaa atcagacgga
    60841 tagcatcgga gcagagcaaa gtttccatac cgctctgcat acacgcagta tttcttcccc
    60901 tgaaaccgtt cgtgaaagcc tgttctgagc tctgtaccct ctcgtttctt caatccagag
    60961 cttatatcca ttcccaccat agcgggatct gtggatgcgg caattctctt cgtatttaag
    61021 tcgaccgcat gaagatatcc gcgcatatcc aggggaatat cagaaatcac ccggtccagg
    61081 ctcttctcct ctatggcctt cagaatacgt tccggctcca ttccaatctg gatgatcccg
    61141 cttccatcct tctcccagac agccgcatac tgcatgggtt tgccctctgc cgtattatca
    61201 gtaatattct ggcagagctt catggaggtg tcctccagca tgggcagaaa ataccgcatc
    61261 tgctctcccg agtcaaacgt atagccgtaa tactccgggt gggttccccc atagatcacg
    61321 ccctccggcg tgaagcagtg gatctcatcc acattcagcc tgtccgccag ctctctggca
    61381 gcttccgggc tctcagtcac ttccggccgg ctctcaatgc agtaggcagc tatctcggca
    61441 gatctaatgc accgctctgc aaactcttcc ttatcctctt caagctccct ttccttcgtt
    61501 tccagcagct gtctcagctg gcagaacagc tcagaagaat tttcccgctg gttcttatgc
    61561 tgggcgtaaa gctgcgccca gagattggcc ggcaggatca gcgcaatcaa cagcaaaatg
    61621 gtagtcctgg ccaggcgcgg cagagccttt ttaatacttc tggttttcat aagcttccct
    61681 ccacgcctca aattctccca ccggaatcgg tctggagtat acatatccct gaatcagatc
    61741 acagcgcatg gcctttaaga cttccacctg ctccatctgt tcaattccct ccgccactac
    61801 gctcatattc aggctgtgag ccagctggat cagctgggcc actattttcc tggactttgt
    61861 attctcattg aggaagaagg tgcggtctaa tttcagagtg tccacctcca gctcgtttaa
    61921 cactcccaga gaggagtagg cgaagccgaa gtcatctaac gccacacgga aaccgcaggc
    61981 gcggaagccg tccagaaccg atttgacgaa cagcagctgg ctgtcgtcga taaatacagt
    62041 ctccgtcagc tctatctcta tcattccgtc tgggatgttg taccgctcct tgatctcctt
    62101 gtactccttc cagacaccgg cgcccttgct tctcaaatgg aaacgggaca gattgaccga
    62161 cagcagggaa atctcctgcc cctcctccat ccatcgggca atcaggcggc agacttcctc
    62221 gaacatatat aaatccagct ggcagatatt tccgttcatc tcaaacagcg gaataaattc
    62281 atccggatag atcatcccct ccttcggatg aatccagcgc acaagggcct ccgcctgaca
    62341 gggctctcct ggaacagggc ttaccttggg ctgcagataa atcttcagat ctctgttttt
    62401 cagggattcc tcaaacagct cgttcagacg ctgctcccga tcctgcttgg cagccacagc
    62461 gttgtcatag aaggtgcaca catttttctc cgccttctgc ttgctggcag aaatcgcccg
    62521 cgtcatagcg gaggaaacag agtctgcgtc ctgcagccgg cagacgccta tagtgaagtc
    62581 aatggaggtg ccgcagaatt tctgtccgat cacctcgttc atctcttgaa tcgcttcctc
    62641 catgcggctg ttcagacggt tcctgtcagt ttcccgaaga agcaggaaga aatgatccat
    62701 gctgctccgg ctgaccagct ctcccttctg cttcaaatcc ttctgaaact gatgaaaaat
    62761 aaactgcagc gtcctgtttc catcctcctc gccccagctc tcattaataa ttctgaaatc
    62821 gatcacattt aagtaaacaa tcgcgtattc tttgaaattt cgattatcta tgacttcttc
    62881 acactgtttt aaaaagccct ccctgttcca gccgcctgtg agcggatctg tgagaaacag
    62941 ctgttccttt ctctgattct ccttcaggag atgacggatc aggaacataa acagaatcat
    63001 aaccgtaaag gtaaagacgg agtagatatc catgtaccgt tcaatctgag acatcagaaa
    63061 atccgacgga ataatggccg cctgctccca gtctgtcccc tccaccttat aggcggaaat
    63121 aaatacctgg cgtcccgagg aaagcgtctg cttatcgatc ccgtagggca tatccctgtg
    63181 ctttaatatc tccttaagct cctcccactc ctcgtccgtt atggcggact cgcttcctct
    63241 tttccttata atccgctcgc ctgtttttcc gtccatgaga acgctgatgc cctgattctg
    63301 gtagtcggcc tggctcacca gcctttggat gccctgatag ctctgcattc ctatgacaag
    63361 agaagccgcc tgcccctcct tcaccacagg cgcggtaaaa agcatcagct gatccttgat
    63421 ataggaaatc tgcggctctt cccaggcctc cggatgagcg gaaagccacg tctccagctc
    63481 ctcggtctcc tccgcctcgg ggaaaaaacc gttttccctg gaaaccacac agatgccgtc
    63541 cagctccgta gcctcctctt tcctggacag cagatcctct gtcatcagaa actccggcat
    63601 cctgctcagc gaatctgcca gatccttgat aaactcctgt cccgtcttca gacggtagga
    63661 aatgtgggaa gccagctcat agttattgtc tgacacatac cgctccacaa tctttcccat
    63721 catccgctca aaagctaccg tattgctgaa aaatccaacc agcacggcaa acgcagccac
    63781 taccgtaatt acaataaaaa ttttgcccct ttttctctct gttttcatct cttcccccat
    63841 ccctgtattt ttcagccgga aaagcttccg ctggacgctt tttctgatgt acagaaaaaa
    63901 aaaccgcttt ctcagtacag tataccaaaa aagcggttat aagttaaggg tttataggaa
    63961 ttggcagaga tgatataccc cgaatgccgc aatccacgca atcaggcact gtccgaatac
    64021 catggccaat gcccattttc ctcccagctc ccttctgaca gaggcgatcg ccgccacgca
    64081 gggcgtatac agaaggcaga atatcaaaag ggccgcggcg cccggcagag tgagggcgct
    64141 ctgcaaggcg gctgtacttc cgaacagtac ggtcagggag gaaaccacgc tctccttggc
    64201 catgaatccg gaaatcaggg cggtgacaat cctccagtct ccaaagcctg ccggaacaaa
    64261 cagaggagcc agcgcgcctg ccagagccgc cagcacgctg tcctgtgaat cggccaccat
    64321 gttgaagctc aaatcaaaat tctgtaaaaa ccagatggca atcgtcgcca ggaaaatgac
    64381 ggtgaaggct ctctgaagga aatccctggc cttgtcccac agaagatggc ctacgttttt
    64441 cgctccgggc attctgtagt taggaagctc catgacgaac ggaaccgcct cccccttaaa
    64501 ggccgtctgc ttcataagca tagccatgat aattcccatg ataattccga acagatacag
    64561 gccaatcatc accagagcgc cgtgatctgg gaaaaaggcc gctgtaaaga aggcgtaaat
    64621 gggcagcttc gctgtgcagc tcataaacgg cgtcagcaga atcgtcattt ttctgtctct
    64681 ctccgacgga agcgttctgc tggccatgac gcccggcacg gtgcagccaa agcccaccag
    64741 cataggcacg atgcttcttc cggacagtcc cagctttctg agaagcttat ccatgataaa
    64801 ggccactctg gccatgtatc cgctgtcctc taagagggac aggaagaaga acagagtcac
    64861 gataatcggc aggaagctta acacgcctcc tactccgccg aagataccgt caatcaccag
    64921 ggaatgcacc gcgccgttca catgagccgc agccatggcc tggtctgcca tctctgtaag
    64981 agcggtaatt cccgattcca aaagtccctg gaaaaaggct ccgacgacgt tgaaggtcag
    65041 ccagaatacc aggcccataa tgccgataaa ggccggaatt cctgtatatt ttcctgtgag
    65101 gaaccggtcg atctcccggc ttctcattct ctcccggctc tcgtggggct tgattaccgc
    65161 atcgctgcag acctcctcaa tatagtcgaa ccgcatctgg gccacagagg ccgcccggtc
    65221 cattccggtc tcctcctctg tctgccctgc gatttcctcc agcacccgct cctcgttctc
    65281 cgtcagctcc agctgcttta agagcgtctg atctccctcc atcaccttgc tggccgcaaa
    65341 gcgcagcgga atctgggcct tggccgcgtg atcctcaatc aggtgcatca cggcgtgaat
    65401 ccctctgtga atcccctcct cccgccggca gaagtcgatc tcaaggggcc gttcctgata
    65461 cttggccacg tgaatcgcat ggcggatcag ctcgtcgatt ccctctccct tggcggcgga
    65521 aatggggatc acaggaacgc ccagagcctc ctccatctcg ttgaccagga cagagccgcc
    65581 gttttcccgc agctcgtcca tcatgtttaa ggccactacc atgggcacac ccagctccag
    65641 aagctgcatg gtcaggtaga gatttctctc aatattggtg gcgtccacga tattgatgat
    65701 tcccttcggc ttctcccgga tgacgaattc ccttgtcaca atctcctcgc tgctgtaggg
    65761 agacatggag tagatgcccg gcagatctgt gatcagcgtg ttgtcgtatc ccttaatcac
    65821 gccgtccttt ctgtctactg tgacgccggg gaaatttccc acgtgctgct tcgagccggt
    65881 cagctggttg aacagcgttg tctttccgca gttctgattt cccaccagtc caaaggtgag
    65941 ggtctctccc tcaggcaggg gattttcctc cttcctgttg tggaaacggc ctccctctcc
    66001 atagcctgga tggtgctttt ctgtcctctg tgttccatga gccgcctgct tcgtctcctt
    66061 tggaggatgg gcttcgctga tctcgatatt ttctgcgtct gccagccgga tagtcagctc
    66121 gtagccgtgg atccgaagct caatgggatc tcccataggg gcgtatttta ccaccgtcac
    66181 ctcggttccc tgaatcagtc ccatatccag gaaatgctgg cgcagcgcgc cgcttccgcc
    66241 caccgcgcag atggtggctg tatttccaat ctgaagttca ctcagtttca tctgtatcac
    66301 cttttcttcc atatctatcg ctttttaaga gacagacagc gtctgccgtc tttctctaat
    66361 ggcttttaaa ttaagttagt tctggcttac cacacgatat cataatacag attttttatt
    66421 ttttcaagca gaaaatggat gcgcggggga gatttttcct gttccgcttt cagccactaa
    66481 aaaatctccc ccgcgcataa tcgctgctct ctgtcttttt tatttcctcc agaattgctc
    66541 ccggaagctg ttctgcggcc ggatcagccg cctttccttc tgcctctgcc cagcgtcccc
    66601 ctcggcagcc cctactctac cttcaccatc ctgtagccta cgcccacgtg ggtctggata
    66661 tactgaggcg cgtctttgga gctgttgatt ttctttcgaa gcgtggccat aaagacgcgg
    66721 agagaggtaa tatcgtcggc ggaattattt ccccagatgt tctgcataat gaacgtatga
    66781 gtcagcactc ttcccacatt tctggctaac aggcacaaaa gcttgtattc aatgggagtc
    66841 aggtgcagct ctgctccgtc cagataggcg cagcctgccg catagtcgat gcgcagcgcg
    66901 ccgtttacaa aggcggaatt ttccgccact gtctgattca tcagcacagg cagtcttctg
    66961 gtgatggctc tcaggcgggc cagaagctcg tccacggaaa agggcttcgt cagatagtcg
    67021 tccgccccgg cgtccagagc ctctattttg tccttgtcct ctgtcctggc gctgatcacg
    67081 ataataggca tattggacca ggagcggatc ttcttaatca cctccacgcc gctggtatca
    67141 ggcagtccca gatccagaag cacaatctcc ggattatggg aggacgcctc aatcaccgcc
    67201 gcagccccgt tcatagccgt taagtaccgg tatccatgtg tttttaaaat cgtagtgatt
    67261 aaattgttga cggatttatc atcctctaca actaaaataa gtggtttatt catgccaccg
    67321 cacctcctct gccggcaatg taaatgtaaa tactgctccg tgggggacgt tgtccgagac
    67381 ggcaatctcc ccgccgtggg cgtttataat agactggcat agggacaggc cgattccgca
    67441 gctgcgccgg ctgtccgcca ccttattttc cccgctgtaa aacatatcga agaccttttt
    67501 cttcgcctcg tcagaaatgc cgtttccatc gtcggcaatg gaaatcactg cctgatcctt
    67561 ctgctttttc acgctgattt gaatatggga gccctggggc gtatattcca ccgcattatt
    67621 gacaaggttg ataatcacct ggacaatcag tctggaatcc attttcgcca gcatgaactc
    67681 atcctcatat tccactgtga tctggtgctc tctgctcttt ttgttcacat gctgaagggc
    67741 ctctgtaatc acatcctcaa tcagatcctc cgttatattc aggttcagct gcccgcccac
    67801 cagccgggta atggaaagaa gattttccac aatgttgatc agccacatgg aatcctcata
    67861 aatgtctgtg tacagccgct ttttcgtctc ctcgtccaga tcgcttccca tggacagcag
    67921 gtttccggca ttgcctgaaa tcgaggtcag gggagttctc agatcgtggg aaatcgcccg
    67981 gagaagattg gcgcgaagct gttcgttctg ggccagcacc gccgcctcct ccttctcccg
    68041 tatgtgcttt tcattctcaa gggccagggc gcactctccc agcacagaca gcaggatact
    68101 gttctcaaag gcttccagcg cagactctgc cagcgctact cccagcacgc catagacatt
    68161 ttcattcacc cggatggcca gatacaggca atgggcgtcg gaaaaagtat tggtggtagc
    68221 ccccgcgtgc ttattatttt taaacgtcca caaagccgcc ttctgttcct tttcagaaag
    68281 gcagcttctg tccgggtctt ccccgcgctc ttctcctgcg gcgggaaaga gtctcggctc
    68341 tccaaggctt ccgttttcct ccggatagat cacaatatcc cggttcagca gcttaatcag
    68401 ctggtttgca gtcacctgga taatatcgtc ccgctccctg gcctgctgca gaagccggtt
    68461 cgtgtcaaac aggatgctcg ttctgaaggc cacccccgcc gactggctgg cgtggctttt
    68521 cagccgcatc accagagatc ctgtgataaa ggccgccaga aacataacca caaaggtcag
    68581 cggataaccg gcatcgtagg cccgcaggga aaagcgcgga actgtaaaca gaaagttaaa
    68641 caccagcacg ctgacaatcg aagaaatcag gccgtagacc tggtttttcg tcaccagagc
    68701 tgtcagcagc acgctgagca cgtagatggt aataatgttg gcctcatcaa tacccagatt
    68761 gtaaaagaaa aatccaatca ggctggcggc gattaaaagg ctcacgctct ttagaatgtc
    68821 tcctgcggaa aaaacaatcc tgcttcttcc gctcttcttc gccctgtacc tggccttctc
    68881 ggagacggca tctggaataa tgtacacatc caagttcggc gcgttcaaaa tcagcttttc
    68941 c
//
LOCUS       DBMDUW010000008        64865 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_487_length_64865_cov_3.118940, whole genome shotgun sequence.
ACCESSION   DBMDUW010000008 DBMDUW010000000
VERSION     DBMDUW010000008.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 64865)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 64865)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64865
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_487_length_64865_cov_3.118940"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            188..1690
                     /locus_tag="ACZPCR_02935"
     CDS             188..1690
                     /locus_tag="ACZPCR_02935"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013976385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent DNA methyltransferase"
                     /protein_id="HIR1229878.1"
                     /translation="MITGELKNKIDSLWDIFASGGLVNPLEVIEQITYLMFIHDLDDS
                     DNTRAKESAMLGLPYQSIFTDEVKIGERIIAGAQLKWSVFHDFPADRMYSVIQEWVFP
                     FIKTLHSDKNSAYSKYMDDAIFKLPTPLVLSKVVDSLDEIYKMMNEIQTADVRGDVYE
                     YLLSKIAQSGRNGQFRTPRHIIRMMVELMDPSSDEVICDPACGTSGFLVAAGEYLKEK
                     KKEEIFFDRQKKDHYMNHMFHGYDMDRTMLRIGAMNMMTHGIDNPFIEYRDSLSDQNP
                     DKEKYSLVLANPPFKGSLDAESVSGDLLKVCKTKKTELLFLALFLRMLKIGGRCACIV
                     PDGVLFGSSKAHKDIRKEIVENQRLEAVISMPSGVFKPYAGVSTAILIFTKTEHGGTD
                     QVWFYDMTADGYSLDDKRNEVKENDIPDIIARFRNLSAEADRKRTEQSFFVPKSEIVE
                     NAYDLSINKYKKVEYVPVEYPSTLEIMTQLREIEMEISQEMEELERLLNL"
     gene            1919..3085
                     /locus_tag="ACZPCR_02940"
     CDS             1919..3085
                     /locus_tag="ACZPCR_02940"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF013579.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HIR1229879.1"
                     /translation="MMMKNKWQYRKIGDVCVVERGSSPRPIDQFITEDGGGINWIKIG
                     DTTESMYITETAQKIKPEGMKKSRYVEPGDFLLSNSMSFGRPYILKIDGCIHDGWLVL
                     KDKDEIFDKRFLYYYLSSKATYQKFKHMAVGGVVNNLNSEMVRKIDVPVPSKDEQMDT
                     ADLLDKICNIISLRKRELNCLDDLIRARFVELFGDPETNPNSWDITKLSRFCDLKNGY
                     AFRSGDYVESSAVLNCRMSNIRPDGGFDAEYHPKFLPDEFWDRYKEYRLKDGDVIIAM
                     TDMANDPKILGVPTIVKTNGKRFLLNQRVGKLTFYNTECINNVYLMFVLSQKHIRQQL
                     VKNAGGSTQINVGKPAILGIEFFVPPMELQEQFAAFVAQVAKSKFTKTFSLLRC"
     gene            3170..6514
                     /locus_tag="ACZPCR_02945"
     CDS             3170..6514
                     /locus_tag="ACZPCR_02945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015542915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HIR1229880.1"
                     /translation="MITNFDYLKQEPKFSRFADVAISAERIILMDPEASIINSRRAME
                     FAVKWMYSVDSDLEMPYQDNLQSLMNAEEYRDIVGPDLWKRMDYIRRCGNNVAHSNKK
                     LGRDEAMLCLENLFIYLDFVACCYSEQYEERSFDKTVITSRIEKARESKAAASAVKAE
                     LEREQEKSAKQELDLQKLMAENASLKEELSARRQEQQQAYVPKPLDLSEYKTRKLYID
                     AMLMEAGWTEGKDWLNEVELHGMPNQSGIGFADYVLYDDMHRPLAVIEAKRTCADVSR
                     GRQQAKLYADLLEQKYKRRPVIFLTNGFETHIIDGQYPERPCAVIYSKRDLEKWFNLL
                     AMRTSLEHVTVDKNIAGRYYQEAAIKAVCRSFDEKNRRKALLVMATGSGKTRTVIALC
                     DCLLKAGWVKNILFLADRNSLVTQAKRSFVNLLPSLSCTNLVEEKDNYNAHCVFSTYQ
                     TMMNCIDTVSDSQGKLFTCGHFDLVICDEAHRSIYNKYRDIFSYFDAPLVGLTATPKD
                     EIDKNTYEIFELENGVPTYGYDLAQAVKDGYLVDYVSVESKLKFMERGIVYDELSEED
                     KEAYEATFGGEQGNLPEAINSSALNSWIFNEDTIKQVLNILMTNGIKIDYGQKLGKTI
                     IFARNHDHAEKILEVFHKEYPSLPDYAKVIDNYMTYAQSAIDEFSDPKKLPQIAISVD
                     MLDTGIDVPEVLNLVFFKKVMSKAKFWQMIGRGTRLCPGLLDGEDKQKFYIFDFCGNF
                     DFFRMNKGKAVANTIPLQGAIFNLQFEISYKLQDMEYQTDRLTAYRKALVDQMSGKVR
                     ELPRDSFAVRQHLKYVELYSEPSGYHALTYEDTLLVREEVAPLIQPDGDEVNAVRFDA
                     LMYGIELAYLVGKKYSKARTDLNRKVAGIAGMSNIPEIQAQSDLINKILHTDYVETAG
                     INEFEEIREKLRDLMKYVSSEKVKYTTNFADELLSMEWKESELENDELKNYKAKAEHY
                     IRQHQDNPAIAKLKTNQPLTQADIEALEETLWHEVGTKQDYEQEFGAKPLGEFVREIV
                     GLDMNAAKEAFSEYLTGTNLDSRQIYFVNQIVEYIVRNGMMKDFSVLQEPPFTDRGSV
                     VEIFTDMSVWLGIKRVIDTINANAAA"
     gene            6593..7456
                     /locus_tag="ACZPCR_02950"
     CDS             6593..7456
                     /locus_tag="ACZPCR_02950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1229881.1"
                     /translation="MKHRVEKTEAAIDYIEGHLSEKLNLELVAEAVHYSKYYLHRIFT
                     QTTGLTVHDYVKRRQLTEAAKLLVFSEKPIVEIAFLAGYESQQAFADSFKAMYKKAPG
                     QYREEREFYPLQLRYCLNREAVEFGGIEDMEQRIRPASEEDIPAWMDLARLAVDGFPC
                     LDEAQHLQWLRECVRQGQAFILKDRETAAGVMGITKETGSIDFLGVHPQYRKTKIAQA
                     FLRKAFSQLEEGRELTVTTFREGDRADTGHRDGLKRLGFAERELLVEFGYPTQRFVLQ
                     KEKLEDGKHEP"
     gene            7446..8798
                     /locus_tag="ACZPCR_02955"
     CDS             7446..8798
                     /locus_tag="ACZPCR_02955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016296626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1229882.1"
                     /translation="MSRDQNQPLGQDFTAASLLKFAFPTMVTMVFMGLYTIGDTIVVS
                     RFVSTDALSAVNIVTPVINLIVGLGSMLAMGGGAVIGRTLGEGRGEEASREFTLLLCF
                     GAALGSLIAGAGTLFCSEIIRGLGSGSLLFPYCQAYLSVLLLFTPAAILQVMFQNWMI
                     TAGRPGLGMALSVGSGAANVLLDLMFVGKLHMGIAGSALGTGIGYLIPTAAGAVFFLR
                     DRGGLRFRKPSFHVRVLAESCANGSSELISQAAAAVTTFLFNRVMMELSGEDGVAAVT
                     IMIYSQFLLTALYIGFSMGVSPVLSYNFGAQNHRQLKRMMKICLTFIVAVSAFIFTAS
                     MISGPALIAAFSPAGTPVYEIAAEGFPVFSLSFLFCGVNIFASAAFTALSDGKTSALI
                     SFLRTFGLIVLFLTILPDVLGVKGVWLAVPAAELGAMAVSVFCLSEGQRAFCLKTERQ
                     "
     gene            8897..9133
                     /gene="secG"
                     /locus_tag="ACZPCR_02960"
     CDS             8897..9133
                     /gene="secG"
                     /locus_tag="ACZPCR_02960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009268048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HIR1229883.1"
                     /translation="MLRGILTFVFVAICVFLTVVVLLQEGKSAGLSGTINGMADSYWG
                     RNKSRSMEGKLEKLTKYGAILWLILALVLNLKVF"
     gene            9412..11511
                     /gene="rnr"
                     /locus_tag="ACZPCR_02965"
     CDS             9412..11511
                     /gene="rnr"
                     /locus_tag="ACZPCR_02965"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HIR1229884.1"
                     /translation="MLVSLMNEEAYVPMKLKELAILLNVPKEQREELKQVLNLLLAEG
                     KISVSKKGKFGKAEAFALVGVFSGNARGFGFVAIEGQEEDVFIPADRTGGALHGDRVQ
                     IVIDSEGRGGRPEGTVVRILEHANETLVGTYEKGKGYGFVIPDNQRISKDIFIPQGCS
                     QGAVSGHKVMVKIRDFGEKKGKKPEGVITEILGHIHDPGVDILSIVRAYNLPEDFPGA
                     VKNQLKQVPDEVKKDSWAGRKDLRDLPTVTIDGEEAKDLDDAISIERAGDGYRLGVHI
                     ADVSHYVQEHTPLDEEAFKRGTSVYLVDRVIPMLPHKLSNGICSLNEGEDRLALSCLM
                     EIDSQGNVTGHEIAETVIRSDRRMTYTAVNAIVTDHDPQVTAEYAEFAEMFLLMKELA
                     DILRKKRHARGSIDFDFPESKIVLDEKGKPLEIKAYERNAATRIIEDFMLLANETVAE
                     DYFWQELPFLYRTHDKPDEDRMKRLGTFINNFGYVLRMPGGQVYPKEIQKLLDKVEGT
                     PEELLISRLTLRSMKQAKYTTENTGHFGLAARYYTHFTSPIRRYPDLQIHRIIKESLH
                     GGLTGKRISHYEKILPQVAVQTSALERRADEAERETDKLKKVQYMERFIGQEFEGVIS
                     GVTSWGFYVELPNTVEGLVHISELRDDYYVFLEERYELSGEMTGKTYKLGQTIRVQLT
                     GCDRFSQTIDFIPAKEF"
     gene            11543..12007
                     /gene="smpB"
                     /locus_tag="ACZPCR_02970"
     CDS             11543..12007
                     /gene="smpB"
                     /locus_tag="ACZPCR_02970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002603796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HIR1229885.1"
                     /translation="MGTNNFKLVANNKKAYHDYFIDDKYETGIELYGTEVKSIRMGKC
                     SIKEAFVRIENGQVYIYGMHISPYEKGNIFNKDPLRQRKLLMHRREIDKLLSKIKEKG
                     FTLVPLQVYFKGSLVKVEIGLARGKKLYDKRDDIAKKDAKREMERSFKAKNL"
     gene            12159..12503
                     /gene="ssrA"
                     /locus_tag="ACZPCR_02975"
     tmRNA           12159..12503
                     /gene="ssrA"
                     /locus_tag="ACZPCR_02975"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(12666..12974)
                     /locus_tag="ACZPCR_02980"
     CDS             complement(12666..12974)
                     /locus_tag="ACZPCR_02980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005924829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000987 - cis-regulatory region
                     sequence-specific DNA binding [Evidence IEA];
                     GO_function: GO:0015643 - toxic substance binding
                     [Evidence IEA];
                     GO_process: GO:0044010 - single-species biofilm formation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HIR1229886.1"
                     /translation="MDGNTTNISIRIDAELKARADTLFSELGMNLSTAFNIFVRQSLR
                     EGGIPFEIRLEQPNKETVEAMLEAERIAKDPSVKGYNDLDELFADLKNGEICTADKKD
                     "
     gene            13149..13967
                     /locus_tag="ACZPCR_02985"
     CDS             13149..13967
                     /locus_tag="ACZPCR_02985"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0071554 - cell wall organization or
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HIR1229887.1"
                     /translation="MGRDITKCHPRLQEAFQQLLAKCSAQGLAVGLGECFRTVAEQDA
                     LYAQGRTKPGSIVTNAKGSSYASQHQWGIAFDFYRNDGKGAYNESDRFFERVGAAGKS
                     LGLGWGGDWSSLVDKPHFYLPDWGSGTKILRSQYRTFEQFKKTWEGMKMEYTYMPIST
                     GNDKVKVTASSLIIRKEPGGEDTGSRYHRRERIAPIEKAVYASERWFRTKRGWISADY
                     LLGWILEDNQWWYIEPGYSYPKGCLKLIDGKCYCFDFNGWMLTSNRIQEGGEII"
     gene            14061..15437
                     /locus_tag="ACZPCR_02990"
     CDS             14061..15437
                     /locus_tag="ACZPCR_02990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013272966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1229888.1"
                     /translation="MTQEMKNDFSKGSVVKNILNLAVPMTLAQLINVLYNIVDRIYIG
                     RIPDHATLSLTGIGLSLPMITMVTAFANLFGMGGAPLCSIERGRGNLEEAEKIMGNSF
                     SMMMLFGVFLTAFGLIFKKPLLYAFGASDATWPFADAYITIYMLGSIFVMVGLGMNSF
                     INSQGFGRIGMCTVLLGAAANLVLDPIFIFGLDMGIQGAALATVISQALSAAWILWFL
                     TGKKAILRLKLSCMKPEFKRIKEITALGMSGFTMAITNCTVQVVCNATLQVYGGDLYV
                     GIMTVINSLREVAIMPVHGVTNSAQPVMGFNYGAREYRRVKKAIVFTSVFSIFYTTLA
                     WALLHGFPEFFIRMFNQDPALIEAGIPALRLYFFGFFMMSLQFAGQAVFVALGKSKQA
                     VFFSIFRKVVIVTPLTLFLPSLLHMGTDGVFIAEPISNFVGGAACFGTMMFTVWRELT
                     RKQYNQRL"
     gene            15543..16613
                     /locus_tag="ACZPCR_02995"
     CDS             15543..16613
                     /locus_tag="ACZPCR_02995"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009290758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HIR1229889.1"
                     /translation="MYNIRIEKTAAPKQKPGADDPLKFGTIFTDHMFVCDYIEGQGWV
                     DPRIVPYQPLALDPSCMVFHYGQEMFEGLKAYKSEDGRTLLFRPDKNWERAKNSNVRL
                     CMPEIPKELFLQALNDLVKLDADWIPTKPGTSLYIRPFMFATDPFLGVRPSNTYKFLI
                     ILSPVGAYYESGLDPVKIWIEDEYVRAVRGGIGEAKTGGNYVASLAAQVKAHDEGYAQ
                     VLWLDGVERKYIEEVGAMNIFFKINGTVVTPQLNGSILPGITRRSAIELCREWGIPVE
                     ERKISVDEIVEAARTGAMEECFGTGTAAVVSPVGELRYENEKMSITGGKIGPVTQRIY
                     DTITGIQLGKIEGPEGWSVEVK"
     misc_binding    16718..16925
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17102..19036
                     /gene="thrS"
                     /locus_tag="ACZPCR_03000"
     CDS             17102..19036
                     /gene="thrS"
                     /locus_tag="ACZPCR_03000"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005333086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HIR1229890.1"
                     /translation="MKITLKDGSVKEYASAMSVIDIAKDISEGLARAACAGELDGETV
                     DLRTVVDKDCQLNILTAKDENGLAALRHTASHIMAQAVKRLYPDTKLAIGPSIADGFY
                     YDVDPESPMTAEDMGKIEAEMKKIVKENLPIERFTLPREEAIAFMQEKAEPYKVELIE
                     DLPEGEEISFYRQGEFVDLCAGPHLMSTKDVGKAYKLLNLAGAYWRGSEKNKMLTRIY
                     ATAFSKKEELEVYITMMEEAKKRDHRKLGKELGLFMMHDAGPGFPFFLPKGMQLKNTL
                     LDYWREIHRKAGYVEISTPVILNRSLWETSGHWDHYKNNMYTTMIDEEDYAIKPMNCP
                     GGVLVYASEPRSYRDLPLRMGELGLVHRHEKSGQLHGLMRVRCFTQDDAHIFMTPEQI
                     KEEIKGVATLINEVYTLFGFKYHVELSTRPEDSMGSDEDWELATEGLRSALEELGLPY
                     VVNEGDGAFYGPKIDFHLEDCIGRTWQCGTIQLDFQLPQRFELEYTGADGEKHRPIMI
                     HRVVFGSIERFIGILIEHFAGAFPTWLAPVQVKVLPISDKYAEYASKVYETLNAAGIR
                     AEMDTRSEKIGYKIREAQTHKIPYMLVVGQKEEEENTVSVRSRFAGDEGASSLDGFIE
                     KLQKEIASKEMRKMEEKKEN"
     gene            19177..19491
                     /locus_tag="ACZPCR_03005"
     CDS             19177..19491
                     /locus_tag="ACZPCR_03005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002565218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HIR1229891.1"
                     /translation="MTRLDCNVTGCVHNAENCCCRNSITVEGKTAREKCDTCCASFDE
                     NKGQMFKNMFKTPESELRVACEAENCVYNKDRFCVAEHIGIAGGNASEAYQTECASFK
                     AR"
     gene            19946..20440
                     /gene="infC"
                     /locus_tag="ACZPCR_03010"
     CDS             19946..20440
                     /gene="infC"
                     /locus_tag="ACZPCR_03010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008722378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HIR1229892.1"
                     /translation="MINEQIRDREVRLIGEHGEQLGIMSAKDAYKLAKEAELDLVKIA
                     PTAKPPVCKIIDYGKFRYEQARKEKEAKKKQKTIEVKEVRLSPNIDENDLNTKVGAAR
                     KFIEKGNKVKITLRFRGREMAHMSKTKYILDDFAEKLADIAVVDKPSKVEGRSIVMFL
                     TAKR"
     gene            20473..20670
                     /gene="rpmI"
                     /locus_tag="ACZPCR_03015"
     CDS             20473..20670
                     /gene="rpmI"
                     /locus_tag="ACZPCR_03015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012742791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HIR1229893.1"
                     /translation="MPKMKTSRAAAKRFKTTGTGKLVRNKAYKSHILTKKSTKRKRNL
                     RKDIVTDATNAKVMKKILPYL"
     gene            20702..21057
                     /gene="rplT"
                     /locus_tag="ACZPCR_03020"
                     /pseudo
     CDS             20702..21057
                     /gene="rplT"
                     /locus_tag="ACZPCR_03020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012742790.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
     gene            21255..21338
                     /locus_tag="ACZPCR_03025"
     tRNA            21255..21338
                     /locus_tag="ACZPCR_03025"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21289..21291,aa:Leu,seq:aag)
     gene            21342..21425
                     /locus_tag="ACZPCR_03030"
     tRNA            21342..21425
                     /locus_tag="ACZPCR_03030"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21376..21378,aa:Leu,seq:cag)
     gene            21624..22361
                     /locus_tag="ACZPCR_03035"
     CDS             21624..22361
                     /locus_tag="ACZPCR_03035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HIR1229894.1"
                     /translation="MLELKNISFEVQEESEQREIIHNLDLTIEDHEFVVITGPNGGGK
                     STLAKLIAGIKTPTEGQIFFDGQDITGKSITERANMGISFAFQQPVRFKGIQVLDLLR
                     LAAHDEKLSVADACVYLSEVGLCARDYINREVNASLSGGELKRIEIATVLARASRLSV
                     FDEPEAGIDLWSFQNLIQVFERMREKTKGSIVIISHQERILNIADRIVVIADGRITKT
                     GRKEEILPEILGTASAVGSCEAYRRDK"
     gene            22361..23278
                     /locus_tag="ACZPCR_03040"
     CDS             22361..23278
                     /locus_tag="ACZPCR_03040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SufB/SufD family protein"
                     /protein_id="HIR1229895.1"
                     /translation="MDEIQKTLLEEVADLHGIPVGAYNIRANGQMAARNTTANIDIVT
                     KEDKSGIDIHIKPGTKHESVHIPVVMSQSGLTEVVYNDFYVGDGADVTIIAGCGIHNG
                     GDAASRHDGIHRFFIGKNAKIRYVEKHYGSGDGNGQRIMNPVTEVTMDEGSYLEMETV
                     QIKGVDSTKRETRAQLGKNAKIVIKESLMTHGNQDAESRFHVDLNGEDSSANVISRSV
                     ARDNSHQLYVSSITGNNRCSGHTECDAIIMDHAKIQAVPELTANDIDAALIHEAAIGK
                     IAGEQLIKLMTLGLTEEEAEAQIVNGFLK"
     gene            23353..24132
                     /locus_tag="ACZPCR_03045"
                     /pseudo
     CDS             23353..24132
                     /locus_tag="ACZPCR_03045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002605284.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
     gene            24190..24663
                     /locus_tag="ACZPCR_03050"
     CDS             24190..24663
                     /locus_tag="ACZPCR_03050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007716888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HIR1229896.1"
                     /translation="MFGQLAKEILSAVVGTVSFSVLFGVPREYYPYCGFIGGAGWLVY
                     CLAELFLPGSGPCFVATAVVILLSRTAAVVKRCPVTIFLIAGIFPLVPGAGVYWTVYH
                     IVMEELFLAVSTGYSAMKEAIAIVMGIVFVFELPQKLFVRMAGWLGSCDFKKRNR"
     gene            24738..26447
                     /locus_tag="ACZPCR_03055"
     CDS             24738..26447
                     /locus_tag="ACZPCR_03055"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HIR1229897.1"
                     /translation="MNDQKLENSLNLALEATKGELEKSAELEAGFDRESGSWELIVRY
                     NGDLEEALDFLPEVEAQILTGGYAVLRVPEPLVDSLASLPQIEYVEKPKLLNFAVNQG
                     RTASCMNPMQAGPDGLTGRGVIVAVIDSGIDFFHEDFRNPDGTTRLLELWDQQLERVF
                     TRQEINEALGQDSREKGEALVPSRDLSGHGTAVAGIAAGNGRESGGTYRGAAYESEIL
                     AVRLGVPGERSFPRTTELMRALDYVVNRALFYQKPAAVNLSFGNTYGSHDGTSLLETY
                     IDQLSNQWKTVIVTGTGNEGSSRGHAAGRYEMGKDTEIELSVAEYETGFGIQLWKLYA
                     DIVEISVVSPGGISTGVLSRRLGAQRIPMGSTELLIYYGKPSPYSQAQEIYLNLLPVG
                     SYVQSGIWKIRLTPRKVAVGQYDLWLPGGGSLNRATRFLVSDPDTTLTIPSTASRVVS
                     VGAYDDSYLSYADFSGRGYTRLNTSVKPDLAAPGVGIMAPRAGGGYGPVTGTSFAAPF
                     VSGSAALMMEWGIVRGNDPFLYGEKVKAYLIRGARPLPGETVYPNQRLGFGRLCLEDS
                     FPV"
     gene            26613..27620
                     /locus_tag="ACZPCR_03060"
     CDS             26613..27620
                     /locus_tag="ACZPCR_03060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004462018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016793 - triphosphoric monoester
                     hydrolase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyguanosinetriphosphate triphosphohydrolase"
                     /protein_id="HIR1229898.1"
                     /translation="MNIREMTEQWETEYLSPYASMSRNTRGRERQEELCDIRPEYQRD
                     RDRILHSKAFRRLKHKTQVFLDPEGDHYRTRLTHTLEVSQIARTIARALRLNEALTEA
                     IALGHDLGHTPFGHAGEAALNRLVPGGFTHAGQGVRVVELLEKQGQGLNLTWEVRDGI
                     LNHRTSGSPATLEGHVVRLSDKIAYINHDIDDAIRAKLFTEEDLPSEYTDILGHSVRE
                     RLNTMIHDLIYQSLDRPEIAMSPGMEAAMHGLRRWMFENVYRGKTARAEEGRAQQLVV
                     SLYHWYMDHPDQLPREYLDRMETRKEELSRTVCDYVAGMTDVFAIERFKELFVPKSFK
                     V"
     gene            27672..29474
                     /gene="dnaG"
                     /locus_tag="ACZPCR_03065"
     CDS             27672..29474
                     /gene="dnaG"
                     /locus_tag="ACZPCR_03065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HIR1229899.1"
                     /translation="MYYPEEVIEEVRTRNDIVDIISGYVKLQKKGSNYFGLCPFHHEK
                     SPSFSVSQSKQMYHCFGCGVSGNVFTFVMEYENYTFREAVELLADRSGVKLPKMEYSK
                     EAKAQADLRAALLEINKMAANYFYYQLKQPQGQQGCQYLMGRGLTEQTIRRFGLGYSN
                     KTSNDLYQFLRSKGYEDSILKETGLVTIEERGARDKFWNRVMFPIMDVNNRVIGFGGR
                     VMGDGEPKYLNSPETKLFDKSRNLYGLNYARLSREKFILLCEGYMDVIAMHQAGFTNA
                     VASLGTAFTSQHAALLKRYTDQVVLTYDSDGAGVKAALRAIPILKSVGMSVRVLNMRP
                     YKDPDEFIKNLGPEAFRQRIAEARNSFLFEIDTIRQQYSMEDPEQKTAFYNETARKLL
                     EFPEALERDNYIQAVAREYFINYEDLKRLVNQMGSRYGTALPGTQAARETGISGEIYG
                     EKPKTFQKKKDREEGIRQSERLLLTWLIEDPRLFDKIQGIIGPEDFVKPLYRRAAQMV
                     FEGHENGEVSPAAILNHFIDDEGNYKEVAALFNASLNDSLSNEEQKKAFADTVMKVKK
                     SSLDYQSRTASDLNELQRIIREQAELANMHISLD"
     gene            29551..30669
                     /gene="rpoD"
                     /locus_tag="ACZPCR_03070"
     CDS             29551..30669
                     /gene="rpoD"
                     /locus_tag="ACZPCR_03070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009460881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HIR1229900.1"
                     /translation="MEEKTLTFEEKLEKLLELARKKKNVLEQKEIIDFFHGEILSPEQ
                     LDQIDEYLENNKVDVLAPDEDLEMEPELFLEEEDLEEEEIDVDHLELSMPEGVNIEDP
                     VRMYLKEIGKVPLLTPEEEIDLAKRMEMGDESAKKRLAEANLRLVVSIAKRYVGRGMQ
                     FLDLIQEGNLGLIKAVEKYDYSKGFKFSTYATWWIRQAITRSIADQARTIRIPVHMVE
                     TINRLIRTSRQLLQELGREPLPEELAKKLDMPVDRVREIMKISQDPVSLETPIGEEED
                     SHLGDFIQDEHVQIPVDAATYTLLHEQLMEVLDTLTDREQKVLRLRFGLDDGRPRTLE
                     EVGREFNVTRERIRQIEAKALRKLRHPSRSRKLKDYLD"
     gene            30720..31439
                     /locus_tag="ACZPCR_03075"
     CDS             30720..31439
                     /locus_tag="ACZPCR_03075"
                     /EC_number="2.1.1.217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0160105 - tRNA
                     (adenine(22)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase"
                     /protein_id="HIR1229901.1"
                     /translation="MKLSKRLEMIASFVKPGSRLADIGTDHGYIPIALTERGVILSAL
                     AMDVRKGPLERAREHIGEAGLAEQIETRLSDGLEKLKAGEADTVVIAGMGGELEIHIL
                     EEGCHIWDSAAQWVLSPQSDLEHVRRYLLEHGFSIDREAMVKEDGKFYTIMDVAGPGR
                     RDAADCSGWRESDYVYGKYLIETADPVLKEFLEQEKKTVSGIFNSLNSRDTDSSKKRA
                     GELKKKLDLIEEAQYEMQGNN"
     gene            31417..32217
                     /locus_tag="ACZPCR_03080"
     CDS             31417..32217
                     /locus_tag="ACZPCR_03080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002564701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HIR1229902.1"
                     /translation="MKCREIIEKLNQLAPEHIACGWDNPGLLAGRRDKAVKRILAAVD
                     ADDAVVEEAIEKGADMLLTHHPLIFKPLKKVNDDDFISRRIMKLIQADISYYTMHTNF
                     DAAPGCMGDLAADRLKLSEREILEPMGFMEDGRPFGIGSVGFLPEEMTVREAAEYVKR
                     VFQLPFVTVYGDDGGSRLVKKAAVCPGAGGSTLENALAKGAQVYITGDMGHHTGIDAA
                     AQGMAVIDAGHFGIEQIFMDFMAEYLSQAFQGEIEVLKASQGLPNCVI"
     gene            32255..33910
                     /locus_tag="ACZPCR_03085"
     CDS             32255..33910
                     /locus_tag="ACZPCR_03085"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002590175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase family protein"
                     /protein_id="HIR1229903.1"
                     /translation="MAAVMIAGERHEYPEGTPYRVIAEDFQEKEQEDILLVRADGKLR
                     ELHKELSGDCSLSFITAEDREGWQTYQRSAVFLMLKAFYDAAGRDCVKKVTVCFSVGQ
                     GLYIEPEGDFELNEELLKAVKDRMEELREARLPIVKKSLNTQEAVEHFHRHGMYDKEK
                     LFRFRRASRVNVYSIDKFEDYFYGYMVPDTGYIKYFDLTLYEKGFVLLLSKRSAPRKI
                     EPLAPRKKLFTVQRQSESWGEKLGIFDVGSLNEAITQGRMNEIILMQEALQEKQIGDI
                     AEQIAARPDRKLVMIAGPSSSGKTTFSHRLSIQMRGLGLNPHPISVDNYFVNRVNSPR
                     DEQGNYDYEALECIDMEQFNADMADLLAGKTVELPQYNFVTGEREYKGDFMTLRKGDI
                     LVIEGIHCLNDRLSYALPKESKFRIYISALTQLNIDEHNRIPTTDGRLLRRMIRDART
                     RGSSAQDTIRMWDSVRRGEERNIFPFQESADVMFNSALLYELAVLKQYAEPLLFGIPQ
                     DAPEYAEAKRLLKFLDYFLGVGSENIPHNSMIREFIGGSCFKV"
     gene            34070..34422
                     /gene="rnpB"
                     /locus_tag="ACZPCR_03090"
     ncRNA           34070..34422
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACZPCR_03090"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            34521..35288
                     /gene="mtnN"
                     /locus_tag="ACZPCR_03095"
     CDS             34521..35288
                     /gene="mtnN"
                     /locus_tag="ACZPCR_03095"
                     /EC_number="3.2.2.16"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002590655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/S-adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HIR1229904.1"
                     /translation="MSTIGIICAGDSELQPYLDMLPFKESKKKAMLTFYECEYQTHRL
                     IALYSGVCKVNGALAAQILIDGYQPDFILNGGTCGGLDENVDIFDTIVAERCIYHDVA
                     EDILTDFHPWMKEPWFLSDEKLLRAAERAQVRRPLRFGAVATGEYFLGAGSRRERLLE
                     KYPEVLAVDMETAAIAHACYVNQVPFLAVRTVTDNGTLPGIGAFEANVEQASAISCQV
                     CLEIIAAYSARSCASSCRETDRNRCGIYEKTGKKQNL"
     gene            complement(35390..35818)
                     /locus_tag="ACZPCR_03100"
     CDS             complement(35390..35818)
                     /locus_tag="ACZPCR_03100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009662666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase regulatory
                     subunit"
                     /protein_id="HIR1229905.1"
                     /translation="MLNISGLKEGIVLDHIEAGKGMDIYFKLGLDKLDCQTAIIKNAR
                     SKKMGKKDIIKIDGGLDVVDLDVLGYIDHSITVNIIKDSKIAEKKSLRLPQKITNVIF
                     CKNPRCITSIEQELPHVFCLADEKKEVYRCLYCEEKYEKK"
     gene            complement(35812..36735)
                     /gene="pyrB"
                     /locus_tag="ACZPCR_03105"
     CDS             complement(35812..36735)
                     /gene="pyrB"
                     /locus_tag="ACZPCR_03105"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002564514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HIR1229906.1"
                     /translation="MRHLLNPLDFSVEEIEALLDLASDIEKHPQKYAHVCDGKKLATL
                     FYEPSTRTRLSFESAMLRLGGSVLGFSSADSSSAAKGESVSDTIRVISCYADICAMRH
                     PKEGAPMVASVHSGIPVINAGDGGHQHPTQTLTDLMTIRSLKGRLDNLTVGLCGDLKF
                     GRTVHSLINALVRYTGIRFVLISPPELRIPDYIREDVLQAKGIEYREVENLDEAMPEL
                     DILYMTRVQKERFFNEEDYIRMKDCYILDKQKMSLAREDMFVLHPLPRVNEISVEVDD
                     DPRAAYFRQVQYGVYVRMALIMTLLEVEKPC"
     gene            36902..37699
                     /locus_tag="ACZPCR_03110"
     CDS             36902..37699
                     /locus_tag="ACZPCR_03110"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008974851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1229907.1"
                     /translation="MAEAQETESGKKTPVIQVKNLYKIYRVGETKVYALNGVDFTMYK
                     GEFCAIVGTSGSGKSTLLNMLAGLEKPTKGEIIISGKHIEKMREDQLVAFRRERVGFI
                     FQSYNLLGTMNAIENIALPLSFQGIGKKERLRQAQKYLKLVGLSHVGDHMPNQMSGGQ
                     QQRVGIARALVVNPKIIFADEPTGNLDSKTTMEVLKLMQRIVREQQQTLVMVTHDDHL
                     AAYADRIFHIIDGKIVKIEENHHSDEAIFGEGGAERQKETSDREDER"
     gene            37696..39561
                     /locus_tag="ACZPCR_03115"
     CDS             37696..39561
                     /locus_tag="ACZPCR_03115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="COG1361 S-layer family protein"
                     /protein_id="HIR1229908.1"
                     /translation="MRMKRLRQVLILLLAVCMMLAGTPFGALAGMMDMTNFNDGRIEV
                     TKVPKGKAGGKVTIRMKIVNDEDSDMEDTTVTLVGGTRYDDILNNVFEQDEDDGDEDD
                     DDDDTIRDYNTQFPFEADSSTFEDKKVGTIRGHSSKTVSITFQLRRDLQPGYYQAFFD
                     LNSSRDHEKTVGVNIWVSASDGSESDEETMDYDITIGENQSTPYGVYGEVLNFGVNLR
                     NSGNRKLYDVRVSMQLDAATEKFPFDINDGNYDRKMGDMDVNQTVSVPYSMAVREDAK
                     SGFYPITYKISYKETEDGDFEEPVDKILYVRVKGEDDDDLEADAGDNERTKARIIVES
                     FSTEPAEVYAGTPFVLKIRMKNASSDVPANNILFTFSSEDTDKNPVFSTESGSSTVVV
                     NSLAPGQSADLELLFNSSPTAEQKSYTMSIKEKYDSPEFKNAEEEVKISIPVKQQPRF
                     STSTIEVMPESISVGSETNVMFGINNTGKVLLYNVTAVFEGDSIQKTDAYVGNIEPGK
                     TGNVDAMISGIAPTADDGKIKITISYEDENGEVTEVEKEMNLLVTETMEEPADMDAMA
                     DMEEMMPEEPSAFSKYKWLILLGAVSAAAGGTAVYRRRKAKKKAQEEEDIDDEIS"
     gene            39548..40897
                     /locus_tag="ACZPCR_03120"
     CDS             39548..40897
                     /locus_tag="ACZPCR_03120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1229909.1"
                     /translation="MRFLDLLTMSVNNLRRRKLRTFLTVLGVVIGTASIVVMVSLGIG
                     LNNFTMETIKSSGSLTAIEIYNYQGMQGDDKTEEDFITDETIKSFSQIPHVTSVYPIL
                     NINVLMKQGIYEGYVTMMGVPLDYMKDIPLGAGKLPSPNADMLEMVVGNMVARNFTNS
                     KTGKGYWDTGEDPDVDFMARPAFVIFDMDAYYQSQSGGGGGEEPVKPPKKYMLNTSAL
                     VEGGPEDYNEYSYSVYVDLNKLKEQLKQIFKKNPIPGQPVNKKGKPYNYFVYEQAVVN
                     VDDMENVKEVQQQLIGMGFEASSRMDWLESSQKQSNMVQAVLGGIGAVSLFVAAIGIA
                     NTMMMSIYERTKEIGVLKVLGCAMGNIRSMFLIEAGFIGFMGGIIGLLLSYGVSGIVN
                     RFLAPGLTDGMTSRISMIPPWLALAAVVFAVFIGMLAGFFPAQRAMKLSPLAAIRNE"
     gene            41098..41520
                     /locus_tag="ACZPCR_03125"
     CDS             41098..41520
                     /locus_tag="ACZPCR_03125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HIR1229910.1"
                     /translation="MELYMLLYRAFHAQRKRLRPYMAQIGLAPGQPKILRYVLNHEGC
                     MQKEAAESCDIEPATISRMIDTLEKGGLVRRVIPENNRRAGSLYLTEKGEESYRLWEA
                     HCREIEKEMLVGFSEGEKKQVADYLSRIYRNLSGRDAL"
     gene            41568..43283
                     /locus_tag="ACZPCR_03130"
     CDS             41568..43283
                     /locus_tag="ACZPCR_03130"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004461980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1229911.1"
                     /translation="MKPCRREFFLAVMFVIIEASFELTIPMLMADMIDVGVADRDMDY
                     IVARGLTMMACALFALVTGLLYARFSARAANGFGAALREAEYRKVQEYSFENLEHFET
                     SSLITRMTADVTVMQNTISGGLRPLTRSPIMLLMGLGMTFYLNKKLVLVFAVCIPVLA
                     FILYHIVSRVAPMYGRLQKAMDQVNAVVQENLNAVRVVKAFVRGEYEEEKFAQVNDNL
                     RETSQTTFHYAVMNLPAFQIVMYTAIVLILWFGGRMTQIGGMQVGELTGFLSYVQQII
                     NSLMMFSGVFLMLTRSLASAKRIGEVFDEPLNLADGEGASQQVECGSVDFDHVFFKYK
                     KEAEEYVLSDVSLHIKAGETVGIIGGTGSAKSTLVQLIPRLYDITSGSLKVGGKDIKT
                     YTLEHLRDAVGIVLQKNLLFSGTIRENLKWGNPDADEEELQWACRAACADEFISRFPE
                     GYDTDLGQGGVNVSGGQKQRLCIARTLLKHPKVLIFDDSTSAVDTATDVKIRAELAKL
                     SDMTKIIIAQRVSSVMDADQIVILEDGNIHAVGKHRELLETDPIYQELYYSQQKGGEE
                     DGETV"
     gene            43267..45126
                     /locus_tag="ACZPCR_03135"
     CDS             43267..45126
                     /locus_tag="ACZPCR_03135"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1229912.1"
                     /translation="MARQFNGKRPKNLKRTVLKLMGYMGNHKFLLLLVAVLVSVSASA
                     GLAGTYMLKPIVNQYIVPGDVEGLFRAVAFTGMIYLCGVAAAYGYTQTMVVAAQKIIY
                     EIRRDLFNHIQSLPLKYFDTRTHGDIMSRFTNDVDTISDAFNNSFAMIVQSFIQIVGT
                     LTLIFVLNWRLSLIVFACYILMFSYIRYSGKKSKYYFNFQQKYLGELNGFIEEMTAGQ
                     KVVKVFNHEQAGIEAFRQKNSQLREAATSALTYSGSMVPVIVSISYVNFAIVAMVGGY
                     MALKGWTDVGSLTSYLVFVRQTAMPINQFTLQSNFMLAAMAGAERIFEAMDEEPEVDE
                     GTVTLVNRKDCPDGTIEESGERTGLWAWKDRRADGTVQLIPLRGDVQFEHVNFGYEPG
                     HPILKDISLYAKPGQKIAFVGSTGAGKTTITNLINRFYDIDGGRLTYDGIDVGRIKKD
                     DLRHSLGIVLQDTHLFTGTIEDNIRYGRLDASGEEVRAAARLANADSFIRRLPKGYDT
                     MVTADGGNLSQGQRQLLAIARAAVADPPVLILDEATSSIDTRTERLIEKGMDRLMEGR
                     TVFVIAHRLSTVRNSDAIMVLEQGRIIERGNHQELIAQRGEYYQLYTGMFELS"
     gene            45307..46581
                     /locus_tag="ACZPCR_03140"
     CDS             45307..46581
                     /locus_tag="ACZPCR_03140"
                     /inference="COORDINATES: protein motif:HMM:NF022641.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HIR1229913.1"
                     /translation="MKKEIALKPPCREYDVQGMESWLQYQSLSGNRLFDTAGRTFYFQ
                     EAEPKKLVFRLEPHGKKQISEEQKEDWKKRGWSYAASYRRLYDIFFSETEERDEAEAL
                     ASSQSVGLQFLDQRFGSWRLLGIFFIALAAVLCWLCWKNGDTILQFLYGNGPFAVLLL
                     AAFTMFWLSAWIMGAWIRGQTEALKAGRPMPEEDYQGSMRKAGKFLKVLQIFWTGTVL
                     LALVMNLSGSSGSLGETAGRSDFLSLAKMEGEYYTPALEQGEPTGQSYRTERNPLVKK
                     NLYVEQSGYKFQTQEELERYAEAGMSDEIAPAREKAREQAAAPGIPVKLELYLYETRR
                     EEDAEKLVNQVCSKYMGISQKADLYQNGIYEFDDASVIQMEENRQIVCARGGKTATIL
                     IYEGDLDMNGQLEYISQAVLAGKDSWKEELAN"
     gene            46674..46949
                     /locus_tag="ACZPCR_03145"
                     /pseudo
     CDS             46674..46949
                     /locus_tag="ACZPCR_03145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583390.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor"
     gene            complement(46982..47185)
                     /locus_tag="ACZPCR_03150"
     CDS             complement(46982..47185)
                     /locus_tag="ACZPCR_03150"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229914.1"
                     /translation="MAGKNIPLRIVIHEPSTDKGKLELARKAAQIHADAVLHIIQSSA
                     KSQEQKKALLDAVIEAALHPPAD"
     gene            47393..48139
                     /locus_tag="ACZPCR_03155"
     CDS             47393..48139
                     /locus_tag="ACZPCR_03155"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019161209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HIR1229915.1"
                     /translation="MRLKDKVAIITGGSRGIGFAAAEKFLEEGASVIITASSQATAEG
                     AVSKLKEKYPEAAVAGIWPNLASLESVRAAFREVEERFGGVDILVNNAGVSESTPFAE
                     YTEEIFNKVMDLNVKGVFHASRAVVESMIKRGGGVILSTSSMVSISGQPSGFAYPASK
                     FAVNGLTVSLARELGPKGIRVNAVAPGIIETDMMRAVPKEVLDPMIEKIPLRRLGRPE
                     DIANAFAFLASDEASYITGAVLSVDGMARA"
     gene            48216..48419
                     /locus_tag="ACZPCR_03160"
     CDS             48216..48419
                     /locus_tag="ACZPCR_03160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004223997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1229916.1"
                     /translation="MERKRKKALVDQRLCVACGCCVKACPVQAVQVVKGIMAKVDWGR
                     CVGCGRCVKECPASVISLQEVKA"
     gene            48416..48985
                     /locus_tag="ACZPCR_03165"
     CDS             48416..48985
                     /locus_tag="ACZPCR_03165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009247571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HIR1229917.1"
                     /translation="MKKQWYDYLWVLSLAYLILGFFNILFAWLGLICFFLPLIISLSK
                     GTKGYCNQYCGRGQLFGILGGRLGLSRKRDMPGWMKGKKFRYGFLVFFLLMFAQMLWN
                     TYLVFAGAQDLKQVVTLLWTWKLPWHWAYHGTLFHEGMAQFAFGFYSVMLTSTVLGIF
                     MMTLFKPRSWCVICPMGTMTQMICRVKNR"
     gene            complement(49018..49677)
                     /locus_tag="ACZPCR_03170"
     CDS             complement(49018..49677)
                     /locus_tag="ACZPCR_03170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015541217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HIR1229918.1"
                     /translation="MDFQNSFPIWNQLTKNQQDRLLGSLMTSRVSKGTVVHNGSADCT
                     GLLLLKSGQLRAYILSDEGREITLYRLFDMDMCLFSASCIMRSIQFEIIIEAEKDTEL
                     WIIPADVYKNIMNESAPAANYTNELMASRFSDVMWLIEQIMWKSLDKRVAAFLLEEAA
                     IEGTYELKITHETIANHLGSHREVITRMLRYFQNEGMVRLSRGMVAVLDEKKLRALQN
                     T"
     gene            49818..50138
                     /locus_tag="ACZPCR_03175"
     CDS             49818..50138
                     /locus_tag="ACZPCR_03175"
                     /EC_number="1.8.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005330449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HIR1229919.1"
                     /translation="MEINREQFEQMVNGEKAVLIDFWAPWCGYCRRLGPAYEKIAEEY
                     NGGGLLTVGKVNIDEEKELAEKEKIEVIPTLVLYKNGTAVDSIVAPESKAMIEAFIEQ
                     ALKK"
     gene            50156..51085
                     /gene="trxB"
                     /locus_tag="ACZPCR_03180"
     CDS             50156..51085
                     /gene="trxB"
                     /locus_tag="ACZPCR_03180"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005344677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HIR1229920.1"
                     /translation="MNTERIYDMLVIGGGPAGYTAALYGTRAGFDTLVLEKLSAGGQM
                     ALTHQIDNYPGFDEGIDGFELAEKMQRQAERFGAKTEYAEVQKLDLTAEPKKVETSEG
                     IFYGKTVVFAAGAAPRKLGIEKEDELIGRGVAYCAACDGMFFKGKTVAVVGGGNSAAA
                     DAMILSRIAKKVLLIHRRDTLRATKIYHEPLMAAENIEFHWNSEVTELLSGEKLTGLR
                     LRNAVTGESEQVECDGVFISVGRTPSTELVGGQLHLDPAGYIVAGETTETNIPGVYAV
                     GDVRTKRLRQIISAAADGAAAAHMAEEHLADRV"
     gene            51179..52897
                     /locus_tag="ACZPCR_03185"
     CDS             51179..52897
                     /locus_tag="ACZPCR_03185"
                     /inference="COORDINATES: protein motif:HMM:NF012464.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HIR1229921.1"
                     /translation="MRKNEDCIAVYSRKSKFTGKGESVQNQEELCREYVRVHYGEDAL
                     NRLILYEDEGFSGGDLNRPGFKNMMDAARKKRFQALIVYRLDRISRNISDFAGLIEEL
                     TRLDIDFVSIKEQFDTGTPMGRAMMYIASVFSQLERETIAERIRDNMHELAKTGRWLG
                     GTTPTGYASETVESVSPGGKTKRACRLRLIPEEADKVRLIYSLYLELDSLAGTEARLM
                     QLGIQTKNGRSFTRFSIRGILQNPVYLTADLEAYEYFEQSGSEIFSEKEAFDGAHGMM
                     VYNRTRQEKGRTTKLLPPGQWIVAVGDHPGLIPGGRWTAVQKSLEQNKIKSYRKPRKN
                     EALATGLLFCSCGSRMYPKLGRRRKTGDGRPYAYVCRTKERSQRQACAADNARGEELD
                     AALTELTGSLKEDKECFLSLLRQGRRFCLSGESGVQIRLSAAKREREEIERKQRGLAD
                     SLAMFQEQEAKEEAVRHMEELGRRRRELDGEIWHLKTILYREILSDSEIREKGRSLSE
                     LAGIMGVMAAEQKRAVLNALIQRIIWDENTAYVILKGVSDEELCQYERLEAHPPVCPA
                     DALGGG"
     gene            52912..53253
                     /locus_tag="ACZPCR_03190"
     CDS             52912..53253
                     /locus_tag="ACZPCR_03190"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HIR1229922.1"
                     /translation="MMLRAGRKRARDVSLYDTIGTDKDGETVSLMDVLEADEIQALDT
                     IIMEQDVKELYQTYETCLKDTEKQVIRMRYGLFGSREHTQREVAAVLGISRSYVSRIE
                     KRAVEKLREAF"
     gene            53383..53946
                     /gene="ahpC"
                     /locus_tag="ACZPCR_03195"
     CDS             53383..53946
                     /gene="ahpC"
                     /locus_tag="ACZPCR_03195"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003500316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HIR1229923.1"
                     /translation="MSLIGKEISEFKVQAYRNGAFQEISKRDVLGKWSVFFFYPADFT
                     FVCPTELADLADKYEEFQDAGCEIYSVSCDTHYVHKAWHDASETIQKIHYPMLADPTG
                     ALARDFDVMIEDEGVAERGSFIVNPEGKIVAYEVTAGNVGRNADELFRRVQASQFVAE
                     HGDQVCPAKWQPGEETLKPSLDLVGLL"
     gene            53970..55274
                     /gene="eno"
                     /locus_tag="ACZPCR_03200"
     CDS             53970..55274
                     /gene="eno"
                     /locus_tag="ACZPCR_03200"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005540026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HIR1229924.1"
                     /translation="MKHLKIEQVIGREIIDSRGNPTVEAEVILEGGVSARAAAPSGAS
                     TGEFEALELRDQDPGRFLGKGVLKAVEAVNTVISRTLCGMDASDIHAADQAMIQADGT
                     EDKSRLGANAILAVSIACARAAAAALEIPLYRFLGGVNGICLPVPMMNILNGGAHASN
                     TVDVQEFMIMPAGADSFREGLRQSAEVFHALRALLSEKKLAVSVGDEGGFAPNLSSDE
                     EAFEYIMEAVRRAGYEPGKDFVFAMDAAASEWKSGKKGEYVLPKSGRRFTSAELVAHW
                     EELADKYPICSIEDGLDEEDWEGWQMMTERLGGRIQLVGDDLFVTNTARLRKGVSLGC
                     GNSILIKLNQIGTVSETLDAVREAHRAGYTAVVSHRSGETEDTTIADLAVALNTCQIK
                     TGAPSRSERTAKYNQLLRIEEELGGAAVYPGFGAFGFTRNFV"
     gene            55365..56381
                     /gene="galE"
                     /locus_tag="ACZPCR_03205"
     CDS             55365..56381
                     /gene="galE"
                     /locus_tag="ACZPCR_03205"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016439515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HIR1229925.1"
                     /translation="MSILVTGGAGYIGSHTCLELLKAGYEVVVADNLCNSSEEAVRRV
                     EKIAGKPVKFYQADILDREALNKIFDTEEIDSVIHFAGLKAVGESVAKPLEYYHNNIT
                     GTLILCDVMRNHGVKNIVFSSSATVYGDPAFVPITEDCPKGQITNPYGQTKSMLEQIL
                     TDFHVADPEWNVVLLRYFNPIGAHESGLIGEDPKGIPNNLVPYIAQVAVGKLQCLGVF
                     GNDYPTHDGTGVRDYIHVVDLAVGHVKALKKIEEKAGVCIYNLGTGKGYSVLDVVKAY
                     EKACGREIKYEIKPRRPGDIATCYADASKAREELGWEAERGIEEMCADSWRWQSANPD
                     GYRS"
     gene            56662..58170
                     /locus_tag="ACZPCR_03210"
     CDS             56662..58170
                     /locus_tag="ACZPCR_03210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002564496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA modification/repair radical SAM
                     protein"
                     /protein_id="HIR1229926.1"
                     /translation="MLIQENLGIQEKLRILSDAAKYDAACTSSGVDRKGKQGQLGSAH
                     EAGICHSFSADGRCISLLKILLTNECVYDCKYCINRRSNDTLRTAFTPEEVCRLTMEF
                     YRRNYIEGLFLSSGIQDSPDHTMEQMLAVAKSLRLEHKFQGYIHLKAIPGASPELVEA
                     AGFFADRMSVNLELPTADGLRKLAPGKTREKILTPMRQIQKGIVKQIAQEGLLEKKGL
                     SSALLSDSGRSFSGSLPDFGEKGRRESRTSPRVIPGRSSYGNYGLGRSASGRSVFVPG
                     GQSTQIIVGATPESDFQMVSVAEALYQNFGLKRVFYSAFVPVSDDSSLPALPGGPPLL
                     REHRLYQADWLMRYYGFQASELLSEEKPNFNVLLDPKCDWAVRNLGRFPVEVNRAPYG
                     ELLRVPGIGVKSAVRIVEARKGTVLRFEDLKKMGVVMKRAVYFITCSGRMMHPVRMDE
                     DFITGCMIGEERRKVWELEQKDTYRQLSLFDDFHMQTEPPAEERAALLTGQL"
     gene            58190..58957
                     /locus_tag="ACZPCR_03215"
     CDS             58190..58957
                     /locus_tag="ACZPCR_03215"
                     /inference="COORDINATES: protein motif:HMM:TIGR03915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03915 family putative DNA repair protein"
                     /protein_id="HIR1229927.1"
                     /translation="MTIFVCKDEFDSILCGVYDAWMSGLGYENVRLITRTEQQNQTMQ
                     MFAEYREAEEASWKIKKTAEAIRRKISQEAYAWIYRASLSRETDKADKIFRFLARGFQ
                     FGPRTVKMLKDPDVYEVFRMNRQVANEAHLLTGFLRFSELPVGLLAAVMGPENHVLSL
                     VADHFAERMSGERWLILDQNRGSAALHEPGYGFVLLPQLPKQWRDSLSGLKGKGEGEY
                     EELWRIFHSAVSIRERENRACQNSHLPLRFRSYMTEF"
     gene            59088..59492
                     /locus_tag="ACZPCR_03220"
     CDS             59088..59492
                     /locus_tag="ACZPCR_03220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007712399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HIR1229928.1"
                     /translation="MILIDYRDRRPIYEQVVEKMADLMIRGILPQDSQLPSVRSLATD
                     LAINPNTIQRAYVELERQGYIYSVKGKGSYVAENHQIREKNRQEVLKSLEALVEKAEA
                     AGVTMLEFQEAVIQMYGKKKKPEEGEGGERYD"
     gene            59485..60384
                     /locus_tag="ACZPCR_03225"
     CDS             59485..60384
                     /locus_tag="ACZPCR_03225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1229929.1"
                     /translation="MIEAVNLTKYYGKIAAVDHVNAEIKEGTVFGLIGTNGAGKSTFL
                     RMAAGILKPDEGSISLDGEPVFENPKAKARFFYISDEQHFLGNSSPEEMAVFYRSVYP
                     AFDRKRFFELLGSFGLDRKRKISAFSKGMKKQLSVLLGICAGTEYLFCDETFDGLDPV
                     MRQAVKRLFANDMETRKLTPVIASHNLRELEDICDHVGILHKGGILLSKDLDDMKMNI
                     HKIQCVLYPGTEPEQIRGLEIIRTEKRGSLLTLTVRGRKEEIERQMQLHHPVFFEMLP
                     LTLEEIFISETEVAGYDIKKLIF"
     gene            60359..62635
                     /locus_tag="ACZPCR_03230"
     CDS             60359..62635
                     /locus_tag="ACZPCR_03230"
                     /inference="COORDINATES: protein motif:HMM:NF039456.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6449 domain-containing protein"
                     /protein_id="HIR1229930.1"
                     /translation="MTSKNLFFKLLREQTKQRIWLIALMCLVSFFAFPVAAALMSGAF
                     LDMEQLTAQADRSAGLLTVEMCRNMASQELIEEFQDWISPTGPLLLWMIPIAAAVAGL
                     AEFSFLHSRRKTDFYHSLPVKREILFAVSYVGGILYVAVPYVIGLLAAGLMIQIKVMP
                     YSVDWGTLLTGALQGIAFFILSYSAASAAAILTGNIVVSILGIFVFFFWGPLTVFLVH
                     AYCQAYFTSFYQAEGILNWLSVSNTSPVFFYWTAGANAGGRALGALAAGAVIGAAAMI
                     LYRKRPSEAAGRAMAFPLSQPLFKIILTIPGALGFSLFFYEMRGSFAWGLFGLFCGVL
                     IMACVIEIIYHFDVRQAFAGWKSTAVGAAAALSIFCLFFFDLAGYDSYLPEQEKIESV
                     GVSSYLLYGNLTQDRTEISAEKGHDGQIFVIGNTPGEYEVLKEMEISDEEAVQAVLEI
                     AEKGISRKNRIGGQEETEAFTSIQNGDGEMTEENVPEESGQVLIQYHLKNGSTATRVY
                     WIDLLDVKEASDRLYASADFKKESYPVFSMDEKELAGANFHVFDTYSHIETGREELAE
                     LFRVYQEEFLQLTADERREEAPLGYIQFKTESMQNTIDQIRAEKGDYTRFNDFAYYPV
                     YPSFERTVSLLREADVKMADSLKTASIDRAVVEMWIDSESRDSFKPYSNDGIRTYLSD
                     SSMCLEVTEPSMVDEILDNVGTSEDPLYRNCLDESMEVVIYVQDGKDGEVDSFRLQFE
                     KGQIPGFVEEQMGAYIFS"
     gene            62705..63211
                     /locus_tag="ACZPCR_03235"
     CDS             62705..63211
                     /locus_tag="ACZPCR_03235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HIR1229931.1"
                     /translation="MAFFDELGKAISGKSREAATKVRDLTEILQLKSKLSSEKEKVNK
                     AYINLGKAYYDRHEVSAEEEYADDFEAIRAGLLKISELEEEIISLEGTRICAECGAKV
                     EKGAAFCGRCGAQMPLKQEETEETFDSSDADAAYTEEQPQQESSIPVPAAEKKTEEIS
                     VTAGRTEE"
     gene            63219..63725
                     /locus_tag="ACZPCR_03240"
     CDS             63219..63725
                     /locus_tag="ACZPCR_03240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="COG2426 family protein"
                     /protein_id="HIR1229932.1"
                     /translation="MDALVQWFTETLSGVMSSEIVIFIISMIPILELRGGLLAASPAL
                     LNVPITTAIPLCIIGNILPIPFILLLINRVLEWMKTVGVFRPTALWLENKAMSKKDKI
                     ENYEFWGLVLFVGIPLPGTGAWTGALIAALLRIRFKKAFLAIFLGIILATVIMSIVSY
                     GLLGALFG"
     gene            63790..64095
                     /locus_tag="ACZPCR_03245"
     CDS             63790..64095
                     /locus_tag="ACZPCR_03245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006442090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
                     /protein_id="HIR1229933.1"
                     /translation="MEECCKSAERHKHRNLTEQKDLMTRLNRIEGQVRGLKAMLEDER
                     YCVDILTQVSAVQAALNGFSRVLLSNHIKTCVVDQIEAGNAEETVEELCKTIQKMMK"
     gene            complement(64184..64327)
                     /locus_tag="ACZPCR_03250"
     CDS             complement(64184..64327)
                     /locus_tag="ACZPCR_03250"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229934.1"
                     /translation="MEEGPGDSPEHMVSIKNGIIHMITNLMPWTAESIGLLLMEKSDM
                     HNS"
BASE COUNT        17697 a        13511 c        18779 g        14878 t
ORIGIN      
        1 aatcagtatg aacccagcag agtttttgga acaggtatta aatttttaaa aacaagatat
       61 tttgaaaaag aggaaggaaa acaattcatg cgtatgtcgt gggaagacgc cgggttaagg
      121 tcgctaaaaa cggcggtttg tgctatacta cacttatgaa aagtatgtat gaaaagcgga
      181 ggaagacatg attacaggtg aattaaaaaa caaaattgac agtttgtggg atattttcgc
      241 ttcaggcggt ctggtcaatc cccttgaagt catcgagcag attacctatc tgatgtttat
      301 tcatgatctg gatgattcag acaatacaag ggcaaaggaa agcgccatgc tggggcttcc
      361 ctaccagagt attttcactg acgaggtgaa aataggagaa cggatcatag ccggcgcaca
      421 gctgaaatgg tcggttttcc atgattttcc ggctgacagg atgtattctg tgatacagga
      481 atgggtattt ccatttatca agacgctgca cagcgacaaa aacagcgcct attccaaata
      541 tatggacgac gcgattttta agctgccgac tccactcgtt ttatccaagg ttgtcgattc
      601 attagatgaa atctataaga tgatgaatga aatccagact gcagacgtgc ggggagacgt
      661 gtatgagtat cttttgtcaa agattgccca gtctggacgg aacggccagt tcagaactcc
      721 caggcacatt atccggatga tggtggagct gatggatcct tccagcgacg aggtgatctg
      781 cgatccggcc tgcggaacat caggattttt agtggcagca ggagaatacc tgaaagagaa
      841 gaaaaaggaa gagattttct ttgacaggca gaagaaagac cactatatga atcacatgtt
      901 tcacggatac gacatggaca gaaccatgct ccgcattggg gcaatgaaca tgatgactca
      961 tggcattgac aatccgttta ttgagtacag agacagtctc tcagatcaga acccggataa
     1021 ggagaaatat tcgctggtgc tggccaatcc gccgtttaag ggaagtctgg acgcagagtc
     1081 cgtgtcaggg gatctgctga aggtctgcaa gaccaaaaaa acagaattat tattcctggc
     1141 gctgtttctg cgcatgttaa aaattggcgg cagatgtgcc tgcatcgttc cggacggtgt
     1201 gctgtttggt tcctcaaagg cacataaaga catcagaaag gaaatcgtgg agaaccagag
     1261 gctggaggcg gtgatctcca tgccttccgg agtgtttaag ccatacgcgg gagtatcgac
     1321 cgctattctg atattcacaa aaacagaaca cggcggaacc gatcaggtct ggttctatga
     1381 catgacagca gacgggtaca gcctggatga taagcgaaac gaggtaaaag agaacgatat
     1441 tccggatatt atagcacgtt tccgcaattt atcagccgag gccgaccgga aacgtacaga
     1501 acagagcttt tttgtgccaa aaagcgagat tgttgaaaat gcatatgatc tttcaattaa
     1561 taagtacaaa aaagtcgaat acgttcccgt cgaatatccc tctacactgg aaatcatgac
     1621 ccagcttcgc gaaatcgaga tggaaatcag ccaggaaatg gaagaactgg aacgactgtt
     1681 aaatttataa gaggaaggat atacaaaatc gatcaattcg gattgaccga gctcttttgg
     1741 gcgagggatg ctccttgcac gaagggcaag aagatgagtg catatgtagc ttgttcacaa
     1801 gcggatgctt ggcggcttgg aagcatagtg cgacagcacg catgagcatg aagcgaagcg
     1861 gaatgcgaat aggcactgct aaatgaggtc gataaatccg atacgagaga gttgtgagat
     1921 gatgatgaaa aataagtggc aataccgaaa gattggcgat gtttgtgtgg ttgaacgagg
     1981 cagttctccg agacctattg atcaatttat aacagaagat gggggtggga tcaattggat
     2041 taaaattggt gacactacgg aatcaatgta tattacagaa actgcccaga aaataaagcc
     2101 ggaaggtatg aaaaaatcca gatatgtgga accaggggat tttcttttat ctaattcaat
     2161 gagctttgga agaccgtata tattgaaaat agatggttgc atacacgatg gttggcttgt
     2221 actgaaagat aaagatgaaa tttttgacaa gagatttttg tattattatc ttagttcaaa
     2281 ggcgacatat caaaagttta aacacatggc agttggtgga gttgtaaata atcttaacag
     2341 tgagatggtt agaaaaattg atgttcctgt cccaagcaag gatgagcaaa tggacactgc
     2401 tgatttatta gataagatat gcaatataat tagtttaaga aagcgagaat tgaattgcct
     2461 agacgacctt atcagagccc gatttgtaga actctttggt gatccagaaa caaatccgaa
     2521 cagttgggat attacaaaac taagtagatt ttgcgattta aaaaatggct atgcttttag
     2581 atcgggagat tacgttgagt cgtctgcagt gttgaactgc cgcatgagca atatcagacc
     2641 cgatggaggt tttgatgctg agtaccaccc caaattcctt ccagatgaat tctgggatcg
     2701 gtataaggag tatcgactaa aagatggcga tgtgataatc gcaatgaccg acatggctaa
     2761 cgaccccaaa atccttgggg ttcccaccat cgtaaaaaca aacggaaaaa ggttcctgtt
     2821 gaatcagcgt gtcggaaaac tcacatttta taatacagaa tgcataaata atgtgtattt
     2881 gatgtttgta ttatcacaga agcacatccg acagcaattg gtaaaaaacg caggaggtag
     2941 tacgcaaatc aatgtgggca agcctgccat ccttggtatt gaatttttcg tgccgccaat
     3001 ggagctacag gagcaatttg ccgccttcgt tgctcaagtc gccaaatcaa aattcactaa
     3061 aaccttcagt ctgctgcgat gttgattttt taaaaattat tcaaactaac agaacatttg
     3121 caaaaactcg tatcaatatg caggaactac aaaaggaggg aggcgctcta tgatcactaa
     3181 ttttgattat ttaaaacagg aaccaaaatt ttccagattt gcagacgtcg ccatatctgc
     3241 ggagaggatt attctcatgg atccggaggc cagcataatc aatagccgcc gggccatgga
     3301 gtttgctgta aaatggatgt attctgtgga ttcggatctg gaaatgccct accaggataa
     3361 tctgcagagc ctgatgaatg ccgaggaata cagggatatt gtggggcctg atctgtggaa
     3421 gcgcatggac tacatcagga gatgcggcaa caatgtagcc cacagcaata agaagctggg
     3481 aagagacgag gccatgctct gcctggagaa cctgtttatc tatctggact ttgttgcctg
     3541 ctgttattcc gagcagtatg aagaacgctc ctttgacaaa actgtcatca cttcccggat
     3601 tgagaaggcg agggaatcga aagcggcagc cagcgccgta aaagcagaac tggaacgaga
     3661 acaggagaag tctgcgaagc aggagctgga tttacagaaa ttaatggcgg aaaatgcttc
     3721 gctgaaagaa gaattatctg cccgcaggca ggaacagcag caggcctatg ttcccaagcc
     3781 gcttgatcta tcagagtata aaacaaggaa gctatacatc gacgccatgc tgatggaggc
     3841 aggctggacg gagggaaagg actggctcaa tgaagtggag cttcatggaa tgccgaacca
     3901 gtctggaatc ggcttcgcgg attacgttct ttacgatgat atgcaccgtc ctcttgctgt
     3961 gattgaggcg aagcggacct gcgcggacgt ttccagggga aggcagcagg cgaagcttta
     4021 cgccgatctg ctggagcaga aatataagag aaggcccgtt attttcctga ctaacggatt
     4081 cgagacgcat attatcgacg ggcagtatcc ggagagacca tgcgcggtca tctattccaa
     4141 gagagacctg gagaagtggt ttaacttatt ggccatgcgg acaagcctgg agcacgtcac
     4201 agtggataag aatattgccg ggcggtatta ccaggaagct gccattaagg cagtctgcag
     4261 aagctttgat gaaaagaacc gcaggaaagc gctgcttgta atggccacag gttccggaaa
     4321 gacgagaact gtgattgcgc tgtgcgactg ccttctgaag gccggctggg taaagaatat
     4381 cctgtttctt gccgatagaa attcccttgt cactcaggca aaacgaagct ttgtgaatct
     4441 tctgcccagc ttatcgtgca cgaatctggt ggaggagaaa gacaattaca acgcccactg
     4501 tgtgttctct acctaccaga cgatgatgaa ctgcattgat acggtcagcg acagccaggg
     4561 aaaactcttt acctgcggcc attttgacct tgtcatctgc gacgaggccc accgctctat
     4621 ttacaacaaa tacagggata ttttctccta ttttgacgcg cctttagtcg ggcttacagc
     4681 tacgccgaag gatgaaattg ataaaaatac atatgagatc tttgaactgg agaacggcgt
     4741 ccccacctat ggatatgatc tggcccaggc ggtaaaggac ggatatctgg tggactatgt
     4801 ctctgtggaa tcaaagctta agttcatgga gcggggaatc gtatacgacg agctgtcaga
     4861 ggaggataag gaggcttatg aggcgacctt tggaggagaa cagggaaatc tgccggaagc
     4921 catcaactct tcggctctca actcgtggat tttcaatgag gacacaatca aacaggtttt
     4981 aaatatcctg atgacaaacg gaataaaaat tgattatggc cagaagcttg gaaagacgat
     5041 tatttttgcc agaaatcacg atcatgcaga gaagattctg gaagtgttcc ataaagagta
     5101 ccccagtctt ccagactatg cgaaagtaat cgacaactat atgacctatg cccagagcgc
     5161 cattgatgaa ttttctgatc cgaaaaagct gccccagatt gccatttccg tggatatgct
     5221 ggatacggga atcgacgtgc cggaggttct gaacctggta tttttcaaaa aggttatgag
     5281 caaggcaaaa ttctggcaga tgattgggcg gggcacaaga ctctgtcctg gtctgctgga
     5341 cggagaagat aagcagaaat tctatatttt tgatttttgc ggaaactttg attttttccg
     5401 aatgaataaa ggaaaagctg tagcaaatac aattcctctt cagggggcga tttttaatct
     5461 gcagtttgaa atttcctata agcttcagga tatggaatat cagacggacc ggctgactgc
     5521 ataccggaaa gcactggtgg atcagatgag cgggaaggtg agggaactgc cgagggacag
     5581 ctttgctgtg cgccagcatc tgaagtatgt ggagctgtat tcggaaccgt ccggctatca
     5641 tgcccttacc tatgaggaca ctctgcttgt cagggaggaa gtggctcctt tgatccagcc
     5701 ggacggggac gaggtaaacg ccgttcggtt tgacgcgctt atgtatggga ttgagctggc
     5761 ttatctggtt ggaaagaagt attcgaaggc ccggacagat cttaacagaa aagtggctgg
     5821 aattgcaggc atgtccaata ttcctgagat tcaggctcag tctgatttga tcaataagat
     5881 tctgcacacc gattatgttg aaactgccgg aatcaatgaa tttgaagaaa taagggaaaa
     5941 gcttcgtgat ctgatgaagt atgtttcttc agaaaaagtt aaatatacga cgaattttgc
     6001 agacgagctt ctttctatgg agtggaagga atcggagctg gaaaatgacg agctgaaaaa
     6061 ttataaggcc aaggcggagc attatatcag gcagcaccag gacaatcctg cgattgccaa
     6121 gttaaagacg aatcagcctt tgactcaggc ggatatagag gcgttggaag agacgctgtg
     6181 gcatgaggtc ggcacgaagc aggactatga gcaggaattt ggcgcgaaac ctctggggga
     6241 atttgtccgc gagatcgtgg gcctggatat gaacgccgcc aaggaggcgt tttcagagta
     6301 cctgaccggt acgaatctgg acagccggca gatttacttt gtgaatcaga ttgtggaata
     6361 cattgtccgc aatggaatga tgaaggattt ttccgtgctt caggaaccgc cgttcaccga
     6421 tcggggaagc gtggttgaga tattcactga tatgagcgtg tggctgggaa tcaaacgagt
     6481 gatagatacc atcaacgcca atgcggcggc ctaggaaaaa atttgtgagc aagaattatg
     6541 aaaacgaaac agccgtctcc tgctatactg ggtgggaaag gaggagacgg cgatgaaaca
     6601 cagggttgag aagacagagg cagccattga ttacatcgaa gggcatttat cggaaaagct
     6661 gaatttagag ctggtggcgg aggcagtcca ttattccaag tattatcttc accggatttt
     6721 tacgcagaca acaggcctga cagtgcacga ttatgtgaag cgcagacagc tgacagaggc
     6781 cgccaagctg ctggtctttt ctgagaaacc gattgtggag attgcctttc tggcaggata
     6841 tgaaagccag caggcgtttg cagacagctt taaggcaatg tacaaaaagg cgccgggaca
     6901 gtaccgggaa gagcgggaat tttacccgct gcagcttcgg tattgtttaa atagagaagc
     6961 tgtggaattt ggcgggatag aggatatgga acagaggatc cgtcctgcct ctgaggaaga
     7021 tattcctgcc tggatggatc ttgccagact ggcggtggac ggctttccat gcctggatga
     7081 ggcgcagcat ctgcagtggc tgagagaatg cgtcaggcag ggacaggctt ttatcctgaa
     7141 ggaccgggag acggcggctg gagtgatggg aattacaaaa gagacgggca gcattgattt
     7201 cctgggagtg catccccagt acaggaagac gaaaatcgca caggcttttc tgagaaaggc
     7261 gttttcccag ctggaggagg ggagggagct gaccgtgacc accttccggg aaggcgacag
     7321 agccgatacg ggccatcggg acggcttaaa gcgtctggga tttgcggaaa gagagctgct
     7381 ggtggaattc ggctatccga cccagaggtt tgtactgcag aaagagaagc tggaggatgg
     7441 gaagcatgag ccgtgatcag aaccagccgc tggggcagga ctttacagca gcttccctgc
     7501 tgaaatttgc ctttcctacc atggtaacta tggtttttat ggggctgtat accatagggg
     7561 acacgatagt ggtttcgcgt tttgtcagca cagacgccct gtctgctgtc aatatagtaa
     7621 ctccggtgat caatctgatt gtaggccttg gctctatgct tgccatggga ggaggcgctg
     7681 tgattggccg gacgcttgga gagggaagag gggaggaggc ttcgagagag tttacccttc
     7741 ttctgtgttt tggggcggct cttggaagcc tcatagcagg cgcaggaacc ttgttctgca
     7801 gcgaaatcat acgcggtctg ggctcaggtt cccttctgtt tccctactgc caggcatatt
     7861 tgtctgtgct tttactgttt acccctgcag ccattctgca ggtaatgttt caaaattgga
     7921 tgattacggc gggacggcct ggacttggca tggctctttc tgtgggatcc ggagcggcca
     7981 atgtgctgct tgaccttatg tttgtgggaa agcttcacat gggaatcgcc ggatctgccc
     8041 tgggcacagg aattggctat ctcatcccca cggccgccgg agccgtcttt tttctgagag
     8101 acaggggagg gctccggttc agaaagccgt cctttcacgt cagagtattg gctgaaagct
     8161 gcgccaatgg atcttctgag ctgatcagcc aggcggccgc agctgtcacc acctttttgt
     8221 tcaatcgggt tatgatggag ctgtcgggag aggacggagt ggccgccgtc accatcatga
     8281 tctactccca atttcttttg actgctctgt acattggatt ttccatgggc gtgtcccctg
     8341 tgctcagcta taatttcggc gcgcagaacc acagacagct gaaacggatg atgaaaatct
     8401 gcctgacttt tattgtggct gtgtctgctt ttatatttac agcatccatg atatctgggc
     8461 cggcgctgat cgccgccttt tcaccagccg gaacgccggt ctatgaaatt gcggcagaag
     8521 gattccccgt tttttcactc agctttctgt tctgcggagt gaatattttt gcgtctgcgg
     8581 cctttaccgc cctctcagat ggaaaaacct cggcgcttat ttcttttctc aggacctttg
     8641 gcctgattgt gctgttttta acgattctgc cagacgttct gggggttaag ggagtgtggc
     8701 tggccgttcc ggcggcagag ctgggggcca tggctgtgtc cgttttctgc ctgtctgaag
     8761 gacagcgggc gttctgcctg aaaacggagc ggcaatagcc cttcggagac agagaacgaa
     8821 agactgttga aaaaagcttg tatttctggg aaaagtatga taggataaac ttgtttgact
     8881 ataggaggtg caaaagatgt tacgagggat ccttaccttt gtatttgttg ctatatgtgt
     8941 atttttgaca gttgtagtat tgcttcagga gggcaagtcg gcaggtttgt ccggtaccat
     9001 taacggtatg gctgacagct actggggaag aaacaagagc cgttccatgg agggaaaact
     9061 ggagaagctt acgaagtacg gagcgattct ctggctgatc ctggcccttg tgcttaactt
     9121 aaaggtattt taactgattc agaaagacac tcttggcagc aggggtgtct tttttagtcc
     9181 acatgaaacg catgggggcg gaaaacgaag aattttacag catcaggaaa cgcatgaaac
     9241 cggtaaaatg cgaaatccta gtaaagcagg tcaaaacagc ctgcgggatg cgcatcctgc
     9301 aggtcaaaca ggaatatctg gagaaaaaca gtgggaaaag aagatagaaa gcagaaaaaa
     9361 ggattagaat acagcggggc agaggcagag cttttagaac agagaaaggc catgctggtc
     9421 tctctgatga acgaggaggc ctatgtgccg atgaagctga aggagctggc gattctgctg
     9481 aacgttccca aggaacagcg ggaggaatta aagcaggtgc tgaatctcct tctggcagag
     9541 ggaaaaatca gcgtatcgaa aaagggcaag ttcggaaagg cagaggcctt cgccctggtg
     9601 ggagtatttt ccggcaatgc cagaggcttt ggctttgtgg ctattgaggg acaggaggag
     9661 gacgtcttta ttccggccga caggacggga ggagcccttc acggagatcg ggtgcagatt
     9721 gtcattgaca gcgagggaag aggaggccgt ccggaaggca cggttgtgcg gattctggag
     9781 cacgccaatg agacgctggt gggaacctat gaaaaaggaa agggatacgg ctttgttatt
     9841 ccggacaatc agagaatatc aaaggatatt tttattcccc agggatgttc gcagggcgca
     9901 gtcagcggcc acaaggtcat ggtgaaaatc agggactttg gagagaagaa ggggaagaag
     9961 ccggaaggcg ttatcacgga gattctggga catatccacg atccgggagt agatattctg
    10021 tctattgtca gggcctacaa tcttccggag gatttccccg gggcggtaaa gaaccagctg
    10081 aagcaggttc ccgatgaggt gaagaaggac agctgggcag gaaggaagga tctcagagat
    10141 ctgccgaccg ttaccataga cggcgaggag gccaaggact tggacgacgc catcagcatt
    10201 gagcgggccg gggacgggta tcgtctcgga gtccacattg cggacgtcag ccattatgtg
    10261 caggagcaca cgccgctgga tgaagaagcc ttcaagcgtg gaaccagcgt gtacctggtg
    10321 gatcgcgtga tccccatgct gccccacaag ctttccaacg gcatctgttc tctcaacgag
    10381 ggggaggacc ggctggccct cagctgcctg atggagattg acagccaggg aaatgtgacg
    10441 ggccatgaga ttgccgagac ggtcatccgc tcggatcgta ggatgaccta cacggcggtg
    10501 aatgccattg tgacggatca cgatccccag gtgacggcgg aatacgctga gtttgcagag
    10561 atgtttcttc tgatgaagga gctggcggac attctgcgga aaaaacgcca tgcaaggggt
    10621 tccattgact ttgatttccc ggaaagcaag attgtgctgg atgagaaggg aaaacctttg
    10681 gaaattaagg cttacgagag aaatgcggcc accagaatta tcgaggattt catgcttctg
    10741 gccaatgaga cggtggcgga ggactatttc tggcaggaac tgcccttcct ctaccggacc
    10801 cacgacaagc cggatgagga tcggatgaaa cgtctgggaa cctttatcaa caactttggc
    10861 tatgtgttaa ggatgccggg cgggcaggtg tatcccaagg aaatccagaa gctgctcgat
    10921 aaggtggagg ggacgccaga agagcttttg atcagccgtc tgacgctgcg ctccatgaag
    10981 caggcgaaat acacgacaga aaacacagga cattttggcc tggcggccag atattataca
    11041 cattttacat ctcctatcag gaggtaccca gatctgcaga ttcatcggat cattaaggaa
    11101 tctctccacg gcggtctgac gggaaaacgg atttcccatt atgagaaaat tctgccgcag
    11161 gtggcagtac agacctcggc tctggagaga cgggctgatg aggcggagcg ggagacggat
    11221 aagctgaaaa aggttcagta catggaacgg tttatcggtc aggaatttga gggcgttatt
    11281 tccggcgtca ccagctgggg cttctacgtg gagcttccga atacagtgga aggactcgtc
    11341 catatcagtg agctcaggga cgattactat gtatttctgg aggaacggta cgagctttcc
    11401 ggcgagatga cgggaaaaac gtataaatta ggtcagacaa tccgggtgca gctgacaggc
    11461 tgcgaccgtt tttcacagac tatcgacttt attccggcca aagagtttta ggcactcgga
    11521 ataaaacatg aggaggaaca gaatgggaac gaataacttt aaattagtgg ccaataataa
    11581 aaaggcatac cacgattact ttattgacga caagtacgag acgggcattg agctttatgg
    11641 gactgaggta aagtccatcc gcatgggaaa atgcagcatt aaggaggcgt ttgtgcggat
    11701 tgagaatggc caggtgtaca tctacggcat gcatatcagc ccctatgaaa aggggaatat
    11761 ctttaataag gatccgctga gacagagaaa gctgctgatg caccgcagag agattgataa
    11821 gcttttgtca aaaataaagg agaagggatt caccctggtt cctctccagg tttattttaa
    11881 gggaagtctt gtgaaggtgg agattggcct ggctcgaggc aagaaactct acgacaagcg
    11941 tgacgatatc gctaagaaag atgcgaaacg ggagatggag agaagcttta aggcgaagaa
    12001 cctgtaagaa gccagagaaa atacaagtgc ccgaggaaaa attttcttgt tccactttaa
    12061 gtcactgaaa atttttcctc gggcttaaac aggaggaggc tatacaaaag atttgacata
    12121 aaactgaaac agtgttaaaa taaaacgaca gtgcataagg gccagtaccg gtttcgacag
    12181 gggctatgca gctggtgaag ctatccgcat gcgatgcgtt aaatggcaaa attaaaatta
    12241 aacgctaacg atagaaaatt agcacttgct gcttaattgc agcagttgtc agccttaggg
    12301 cactcacacc ttaagaatct ggcatcgacc atgtgagaaa cgatggcggg agggcaccgg
    12361 accgtcaggc gtatcagggg ctactgaagt tctgaggatg ttcgtttccg caggatggag
    12421 ggaatgaaaa agaacggact atgatagtag aagaacaggg aattggttct tggacacggg
    12481 ttcgactccc gtctggtcca ctcacgatga acccttgtaa atatgggatt tttcctttat
    12541 ttacaagggt ttttctatgt ttgtggtgaa gtgctattgc actaaaaaga agcccttttt
    12601 tcatgcttta tgcaacacga atgcaacacg aaaatcacac gttttttatt ttctcaaagt
    12661 gctgattaat cttttttgtc tgccgtacag atttctccat ttttcagatc agcaaacaat
    12721 tcgtcaaggt cattgtaacc ttttacagac ggatctttcg caatcctttc cgcttccagc
    12781 atggcctcaa ctgtttcttt attaggctgc tccagcctta tttcaaaggg aatgccgccc
    12841 tcgcgaagcg actggcgcac aaagatgtta aacgctgtac tcaggttcat gccaagctct
    12901 gaaaaaagtg tatctgcccg ggcttttagc tctgcgtcta tgcggatact gatgtttgtg
    12961 gtatttccat ccatacgatc aactcctttc tgctgataat tatagtacat gatgtttgca
    13021 cgaaaaaaca atattttgca cgaatattta acgataaatt cattcaagtc ggtaaatagg
    13081 agtctgatct gggaacaggc tctgcagaag cgaatacaat ataaaaaaga gttttaagga
    13141 aagaaataat gggaagggat attacgaaat gccatccccg cctgcaggag gccttccagc
    13201 agcttttggc taagtgcagc gctcagggcc ttgctgttgg tctgggcgag tgttttcgga
    13261 ctgtggcgga gcaggatgcg ctgtatgccc aggggcggac gaagccgggg agtattgtga
    13321 ccaatgcaaa gggatccagc tacgcttccc agcaccagtg gggaattgcc tttgactttt
    13381 acaggaacga cggaaaagga gcttacaacg aatcggatcg attttttgaa cgggtaggcg
    13441 cggcagggaa aagcctgggc cttggatggg gaggcgactg gagcagcctg gtggataaac
    13501 cgcattttta tctgccggac tggggcagcg ggacaaaaat tttgagaagt cagtatagaa
    13561 cctttgaaca gtttaagaaa acgtgggagg gaatgaagat ggagtatacc tatatgccca
    13621 tcagtacagg aaatgataag gtaaaggtga cggcctcttc tctgattatc agaaaagaac
    13681 ctgggggaga agatacagga agcagatacc accggagaga acgaatcgcg ccgatagaaa
    13741 aggcagtata tgcttccgag cgctggttta gaacaaaaag aggctggatc agcgcagact
    13801 atctcctggg ctggattctg gaagacaacc agtggtggta tattgagccg ggatattcct
    13861 atccgaaagg ctgcctgaag ctgatcgacg gcaaatgcta ctgctttgat tttaacggat
    13921 ggatgctgac gtccaatcgg attcaggagg gaggagagat catttagcgc ggcctcttga
    13981 aatacagagg gaaatattgt attatttttt caagaagtat atacaattta ccttgcttta
    14041 actgggggag agaaaagaga atgacacaag agatgaaaaa tgatttttca aagggcagtg
    14101 tggtgaaaaa cattttaaat ctggcagtgc ccatgacatt ggcccagctg atcaatgtgc
    14161 tttacaatat tgtcgacaga atctacattg gaagaattcc ggatcacgcc actctgtctc
    14221 tgacgggaat cggcctgtct cttcctatga ttaccatggt gacagccttt gccaatctgt
    14281 tcggaatggg aggagcccct ctctgttcta ttgagcgggg aagagggaat ctggaagaag
    14341 cggaaaaaat catgggaaat tctttttcca tgatgatgct gttcggcgta tttctgactg
    14401 cgttcggtct gatttttaag aagcctctgc tctatgcgtt cggagccagc gacgcgacct
    14461 ggccctttgc agacgcctac attaccatct atatgctggg cagtattttc gtgatggtgg
    14521 ggctgggaat gaacagcttt atcaattccc agggctttgg caggattggc atgtgcacgg
    14581 tgcttttggg ggcggcagcc aatctggtgc tggatccgat ttttattttc ggcctggata
    14641 tggggattca gggagccgcg ctggctactg tgatttccca ggctctctcc gccgcctgga
    14701 ttctctggtt tttgacggga aagaaggcaa ttctgcgtct gaagctgtcc tgtatgaagc
    14761 cggagtttaa gagaattaag gaaattactg cccttggcat gagcggattc accatggcca
    14821 tcaccaactg caccgttcag gtcgtctgca atgcgacgct ccaggtatac ggaggcgatc
    14881 tctatgtggg aattatgacg gtcatcaact ctctcaggga ggtggcgatt atgccggttc
    14941 acggcgtgac taacagtgcc cagccggtga tgggctttaa ctacggagcc agggagtaca
    15001 gaagagtgaa aaaggccatt gtgtttacct ccgtattttc cattttttac acgactctgg
    15061 cgtgggcgct gctgcacggc tttccggagt ttttcattcg gatgtttaac caggatccgg
    15121 ccctgattga ggcgggaatc ccggccctcc gtctgtactt ttttggattt ttcatgatgt
    15181 ctctccagtt tgccggacag gctgtgtttg tggctcttgg aaaatcgaag caggcagtgt
    15241 tcttttctat tttccggaag gttgtgattg tgactccgct gaccttgttc ctgccgtcgc
    15301 tccttcacat gggaacagac ggagtgttta tcgcggagcc gatttccaat tttgtgggag
    15361 gagcggcctg ctttggaacc atgatgttca ctgtatggcg ggaactgacg agaaaacagt
    15421 ataaccagcg gttatagtgt tattctattt acagaaaatg aaagaatcgt attgacaata
    15481 cagaacctat ctatgataat ggagtatatt attactttga acggaaagga agggtgaagc
    15541 ccatgtacaa tataagaatc gagaaaacgg cagcgccgaa gcagaagccg ggagcagacg
    15601 atccgctgaa gtttggaact atttttacag atcacatgtt tgtgtgcgat tacatagaag
    15661 gacagggctg ggtagatccc agaattgtcc cctatcagcc ccttgcgctg gatccgtcct
    15721 gcatggtatt ccactatggc caggagatgt tcgagggctt gaaagcctat aagagcgagg
    15781 atggaagaac gctgttgttc cgccctgaca agaactggga gagagcgaaa aacagcaacg
    15841 tgcgcctgtg catgccggag attcccaagg aactgttttt acaggcctta aatgatctgg
    15901 tgaagctgga cgcagactgg atccccacaa agccgggaac ctctctgtac atccgcccgt
    15961 ttatgtttgc cacagacccg ttccttggag tccgtccgtc gaacacctac aagtttctga
    16021 ttattctgtc tccagtaggc gcttactacg agagcggcct tgacccggtt aaaatctgga
    16081 ttgaggacga gtatgtcaga gcggtaagag gcggcatcgg agaggctaag acaggcggaa
    16141 actatgtagc ttccctggcg gctcaggtga aggcccatga cgagggctac gctcaggtac
    16201 tgtggctgga cggtgtggag agaaaataca tcgaggaagt aggagcgatg aacattttct
    16261 tcaagatcaa cggaacggtt gtgacgcctc agttaaatgg aagcattctg cctggaatta
    16321 ccagaagatc cgccattgag ctgtgcagag agtggggcat tccggtggag gagagaaaga
    16381 tttccgtaga cgagatcgtg gaggctgcca gaacaggagc tatggaagag tgttttggaa
    16441 ccggcacggc ggcagtggta tccccggtcg gagagcttcg gtacgaaaat gaaaagatga
    16501 gcatcacagg cggcaagatc ggtcctgtca cccagagaat ctacgatact atcacaggca
    16561 ttcagctggg aaagatagag ggacccgagg gctggagcgt agaggtaaag taagagacag
    16621 cagcaaaatg cctgcggcaa acgcagaaaa tcgcttgaca aaacggcagt caatgctata
    16681 atcaaagaga atagaagact aatcatgtcc agatacagcc aacacgctga gaagaagagt
    16741 aggccggaag aagctgtcca gagagagagg cgtcaggtgg aagcctctta cagaagaacc
    16801 gtctgaagac catctttgag tgtcccttaa tcgggaacgg tgattccgtt atcatcacaa
    16861 tgagaggcgc agagccttat tgcctgcgca accagggtgg aaccgcgagt aaagtcgtcc
    16921 cttgttatac ataaccgtat aacaggggac ttttttattt cataggaaaa agcgtcctat
    16981 gaaatatgaa ataaaaaatg ctccgcgaaa atctttcctg tttcagaggg aatgtgcagg
    17041 gattgtatca gacatgaaaa cagccagtag aaacagctga caaagcaaag gagataaaaa
    17101 catgaagatt acattaaaag acggctctgt aaaagagtac gcatccgcta tgtctgtcat
    17161 tgacattgca aaggatatca gcgagggcct tgccagagct gcctgtgcag gagagcttga
    17221 cggagagact gtagatctga gaacagtagt ggacaaggac tgccagttaa atattctgac
    17281 agcaaaggat gaaaatggac tggcagcgct gcgccataca gccagccaca ttatggccca
    17341 ggctgttaag agactgtacc cggacacaaa gctggcaatc ggaccttcca ttgcagacgg
    17401 attctactat gacgtggatc cggaaagccc tatgacagca gaggatatgg gaaaaattga
    17461 ggctgagatg aaaaagatcg tgaaggagaa ccttccgatt gagcgtttta ctcttccaag
    17521 agaggaagct atcgctttta tgcaggagaa ggcagagcct tacaaggtag agctgattga
    17581 ggatcttccg gagggagaag agatcagctt ttaccgtcag ggagagttcg tagatctctg
    17641 cgccggcccg cacctgatga gcacaaagga cgtaggcaag gcttataagc tcttaaatct
    17701 ggccggagct tactggcgcg gaagcgagaa gaacaagatg ctgacacgta tctacgccac
    17761 agctttctcc aagaaggagg agttagaggt ctacatcact atgatggagg aggccaagaa
    17821 gcgtgaccac agaaagctgg gcaaggagct gggcttattt atgatgcacg acgcaggccc
    17881 tggtttccca ttcttccttc ccaagggaat gcagcttaag aacacgcttc ttgactactg
    17941 gagagagatc caccgcaagg caggatatgt ggagatttcc acaccggtta tcttaaacag
    18001 aagtctctgg gagacctccg gacactggga tcactacaag aacaacatgt atacaaccat
    18061 gatcgatgag gaagactacg caattaagcc gatgaactgt ccgggaggcg ttcttgtata
    18121 tgcttctgag ccaagatcct accgcgatct gcctctgcgc atgggagagc tgggactggt
    18181 tcaccgccac gagaaatcag gacagctcca cggcctgatg cgcgtgcgct gcttcacaca
    18241 ggacgacgct catatcttca tgactccaga gcagatcaag gaggagatca agggcgttgc
    18301 cactctgatt aacgaggttt acactctgtt cggcttcaaa tatcatgtag agctttccac
    18361 cagaccggaa gacagcatgg gaagcgacga ggattgggag cttgcaacag agggccttag
    18421 aagcgccctt gaggagctgg gacttcctta tgtggtaaac gagggagacg gagccttcta
    18481 cggaccgaag atcgacttcc atctggagga ctgcattggc agaacatggc agtgcggaac
    18541 catccagtta gacttccagc ttccgcagcg ttttgagctg gagtacacag gagcggacgg
    18601 agaaaagcac agaccgatta tgattcaccg cgttgtattc ggctccatcg agcgttttat
    18661 cggaatctta attgagcact ttgcaggcgc cttccctaca tggctggctc cggtacaggt
    18721 aaaggttctt ccaatttccg acaaatatgc ggagtacgct tccaaggtat acgagactct
    18781 gaacgccgcc ggaatccgcg ctgagatgga tacacgttct gagaaaatcg gctacaagat
    18841 ccgcgaggcc cagacccata agatcccata catgctggta gtgggacaga aagaggagga
    18901 ggagaataca gtgtccgtga gaagccgttt cgcaggcgac gagggcgctt cctccttaga
    18961 cggatttatc gagaagcttc agaaggagat cgcatccaaa gagatgagaa agatggaaga
    19021 gaaaaaggaa aattaatccg tttcttctat ctataatgca gttcttccag ttttgtccgg
    19081 aagaataaaa agtccgaatc atcgcataat aatcctgaac aagaaaaccg ctcctgcctg
    19141 aatcaggaca gggccggata aaggaggact tttgcgatga caagacttga ctgcaatgta
    19201 acaggatgtg tacacaacgc cgagaactgc tgctgccgaa actctatcac agtagaggga
    19261 aagacggcca gagagaagtg cgatacctgc tgcgccagct tcgacgagaa caagggacag
    19321 atgtttaaga acatgtttaa gaccccggag agcgagctga gagtagcctg cgaggcagag
    19381 aactgcgttt acaacaagga tcgattctgc gtggcggagc atatcggaat tgccggaggc
    19441 aatgcttcgg aggcttacca gacagagtgc gcaagcttta aggcgcgcta agccaggata
    19501 ggaaccggcg ctaagatacg gtaagataag gggagaaagg agatctttgt ttagaagaac
    19561 tcgtttctcc cttttttgca tggaagacag gactgggaaa cggatttgaa acatgtctgc
    19621 aaaacatttg ccaaaatgtc tgtgaaacat ttgcaaaaag tccttgacga aacggggagc
    19681 ctatagtata atactaaaag ttgtgagaaa caacatcagg aaagcaggta tccgcctcac
    19741 cctggcacat acagtgacca gcggttcata caaagtagag aatgatccag aaatggaatt
    19801 tcctatcgtt tatgagcggg tagtctgact gcccgctttt tattgttttg tgccgggccg
    19861 gagaaaggct gacagggcag aaaacagtta gtatattgat tcattcatca tcacagtatg
    19921 gaggtggacg gctattagcg atttaatgat taacgaacag attagagaca gagaggttcg
    19981 tttgattgga gaacacggag agcagcttgg tatcatgtct gcaaaggatg cctacaagtt
    20041 ggcaaaggag gcagagcttg atttagtaaa gattgctccg acggcaaagc cgccggtctg
    20101 caagattatc gattacggaa aattccgtta cgagcaggcc cgcaaggaaa aagaagctaa
    20161 aaagaaacag aagacaatcg aggtaaagga agtacgcctg tccccgaaca ttgacgaaaa
    20221 cgacctaaac acaaaggtgg gagcggccag aaagttcatt gaaaagggaa acaaagttaa
    20281 gattactctt cgtttcagag gccgtgagat ggctcacatg tccaaaacca aatacatcct
    20341 cgacgatttc gctgagaagc tggccgacat tgcggttgtc gacaagcctt ccaaggttga
    20401 gggaagaagc attgtgatgt ttttaactgc aaaacgttaa aaatagacca ttatctaagg
    20461 aggaaaataa acatgcctaa aatgaaaaca agcagagcag ctgctaagcg ttttaaaaca
    20521 acaggaacag gaaagttagt aagaaacaaa gcttacaaat cccatatctt aactaagaaa
    20581 tctactaaga gaaagagaaa tcttagaaaa gacatcgtta ctgacgctac aaacgcaaaa
    20641 gtaatgaaga agattttacc atacttataa gattgagaga ttaagaagga ggaaataacc
    20701 gatggcaaga attaaaggcg gattaaacgc taagaagaaa cataacagag tgttaagctg
    20761 gctaaaggct acagaggcgc tcgttccaaa cagtatagaa tcgcaaagca gtctgtaatg
    20821 agagcattaa agagctccta tgcaggacgt aaggagagaa agagacagtt cagacagctc
    20881 tggatcgcac gtatcaacgc tgctgcacgt atcaacggct tatcctacag caagttcatg
    20941 tacggcttaa agctggctgg tgttgagatg aaccgtaagg tattatccga tatggctatc
    21001 agcgacgcag agggcttcgc aaagttagca gagttagcta agtccaaact ggcttaattc
    21061 tgacagcgga aaacagtata agcggctgct gggagagagg aaactttctt tcagcagcta
    21121 tgttattttg taaataatat atacaaatgc aattgacaaa aaaattaaaa aaattgcaaa
    21181 aaagacttgc caaatcctgg atactgtgat atactacata tcgtcgaaag gaaatcggca
    21241 gaaaaaaaga ataagcggga gtgctggaat tggcagacag gctagactaa ggatctagtg
    21301 gttgtatgat cgtgtgggtt caagtcccat ctcccgcata cgcagaagtg gcggaattgg
    21361 cagacgcgca cggttcaggt ccgtgtggta gcaataccgt gagagttcaa gtctcttctt
    21421 ctgcacgata aagagttctg agaaatcagg gctctttttt gcgtaaagga acgagggcag
    21481 agggaataaa aaagagaatg aaaaaagtta aaacatcttg ggaagcagta tagtaaaacg
    21541 cggcaattta gtatataata cccatgtgca ggaatctgac agacagaggg gattcctgaa
    21601 atacgataca gaggaggacc gctatgctgg aacttaagaa tatttcattt gaagtccagg
    21661 aggagtcaga gcagagagag atcatacaca acctggattt aaccatagag gatcatgaat
    21721 tcgtagtgat tacagggcct aacggaggcg gcaagtctac cctggccaag ctgattgcag
    21781 gaattaagac gcccacagag gggcagattt ttttcgacgg acaggacatt accggaaaga
    21841 gcattacaga gagggctaac atgggcatca gctttgcctt ccagcagccg gtgcgtttta
    21901 agggaattca ggtgttagat ctgctccgcc tagcagccca cgatgagaag ctgtctgtgg
    21961 cggacgcctg cgtctacctt tccgaggtgg gactctgcgc cagggactac attaacagag
    22021 aggtgaacgc aagcctttct gggggagaat taaagcgaat cgagattgcc accgtattgg
    22081 ccagagcttc caggctctct gtgtttgacg agccggaggc aggaatcgat ctgtggagct
    22141 tccagaacct gattcaggta tttgagcgga tgagggagaa gacgaaggga tccattgtta
    22201 tcatttccca ccaggagaga attctaaata ttgcagacag aatcgtagtg attgcagacg
    22261 gaagaattac aaagaccggc agaaaggaag agatccttcc ggagattctg ggtactgcgt
    22321 ctgcagtggg atcatgtgag gcttacagga gggacaaata atggacgaga ttcagaagac
    22381 gcttttggaa gaggtggcag atcttcacgg gattcctgtg ggggcctaca atatcagagc
    22441 caacggccag atggcggcga gaaatactac ggcaaatatt gacattgtaa cgaaagagga
    22501 caagtcggga atcgacattc acattaagcc tggtacgaaa catgagagcg tacatatccc
    22561 tgtggtgatg agccagagcg gtctgaccga ggtggtgtac aatgactttt atgtgggaga
    22621 cggggcggat gtgacgatta ttgccggctg cggcattcac aacggaggag acgctgcgtc
    22681 cagacacgac ggaatccacc ggtttttcat cggaaagaac gctaaaatcc gctatgtgga
    22741 gaagcactat ggaagcggcg acggaaatgg acagcgcatc atgaatccgg tgacagaggt
    22801 gaccatggac gagggcagtt acctggagat ggagaccgtg cagatcaagg gcgtggactc
    22861 tacgaagagg gaaaccaggg cgcagcttgg aaagaatgcc aagattgtca ttaaggaaag
    22921 cctgatgact cacggaaacc aggatgcgga aagccgcttc catgtagact taaacggaga
    22981 ggattccagc gccaacgtga tttcccgctc tgtggcaaga gataactctc accagcttta
    23041 tgtgtccagc attacgggaa ataaccggtg cagcggccat acagagtgcg acgctattat
    23101 catggatcac gcgaaaattc aggcggtgcc tgagctgacg gccaatgata ttgacgcggc
    23161 tttaatccac gaggcggcga ttggaaagat tgcgggagag cagctgatta agctgatgac
    23221 tctgggactg acagaggaag aggcggaagc tcagatcgtc aacggatttt taaaatagga
    23281 aagaacagac agaagcgctg aaaggcctgg gaactcttgc ccgggccttt cgtgccatag
    23341 aggagaaacg atatggggaa gcagtcggat gaggaggttc tcgatctggc cctgatggcg
    23401 gggcatattc ttctggaaaa cggagcggag atttaccggg tagaggagac catcgacaga
    23461 atctgcgggt attacggggt taattcagaa aacgcgtttg ttttgagcaa tggaattttt
    23521 ctgacagcgg gaagcgcaag ggaaagcttt tttgcaaagg tgcagcacat tcctgtcagc
    23581 ggaacgcatt tgaataaggt ggcggctgtc aaccagctgt ccagagagat tgtggagggg
    23641 aaacatacaa tccaggatgc ataccggatc ctggaggaaa tcaggactat gccgggcaag
    23701 aaacggtgga tgcagactct ggcctccggc gtgggaagcg cggcattctg catttttttc
    23761 ggaggcacgt ttggggacag cctggcggcc tttgcggccg gaatctgcct gtatctgtac
    23821 gtgctctggc tcagcgtccc ccatctttca aagattgtgg gaaacattgg gggaggagct
    23881 ctggttacgg tggtctgctg ccttctttac ctgatgggag tgggagaaaa tctgaatttt
    23941 atgatgatag gcacgatcat gccgctggtg ccgggagtgg cgtttacgaa ctccatccgg
    24001 gacgtggcgg acggagacta catatccggt tcagtcagga tgctggatgc gctgctggta
    24061 tttttctgca ttgccatagg tgtgggaatt ggcttttccc ttatttccct ggttccggga
    24121 agcgggacgc ttcaggaaat gggacagctg gcggaaggct ctggaagcgg ggccatggga
    24181 ggcatcgaga tgttcggcca gctggcgaag gaaattttat cagcggtagt gggaacggta
    24241 agcttttccg tattgttcgg cgttcccagg gagtattatc cttactgcgg tttcattgga
    24301 ggcgcaggat ggctggtcta ctgtctggca gagctttttt tgccgggatc cggtccctgc
    24361 tttgtggcta ccgcggtagt gattctgctt tcgagaacag ctgctgtggt gaagcgctgt
    24421 ccagtgacta tctttctgat tgccggcatt tttccgctgg tgccgggagc cggcgtgtac
    24481 tggacggtgt accacattgt gatggaggaa ctgtttctgg cagtatccac aggatattcg
    24541 gccatgaagg aggccattgc cattgtaatg ggaattgtgt ttgtgtttga acttccgcaa
    24601 aagctgtttg tgcggatggc cggctggctt ggatcctgcg atttcaagaa aagaaataga
    24661 tgaaaaacag gaaatcagtc attttttctg acgcatcggc ataaatatag aagtaataga
    24721 ttggtaagtg tgtgcagatg aatgatcaga agctggaaaa cagcctgaac ctggctttgg
    24781 aagccacaaa gggagagctg gaaaagtcgg cggagctgga ggctggattt gacagggaaa
    24841 gcggcagctg ggagctgatt gtccggtata atggggatct ggaggaagct ctggattttc
    24901 ttccggaggt ggaagcgcag attttgacag gcgggtacgc tgttttaagg gttccggaac
    24961 ctctcgttga ctccctggca tcccttcccc agattgagta tgtagaaaaa ccgaagcttc
    25021 ttaattttgc ggtcaatcag gggagaaccg cctcctgcat gaatcccatg caggccggtc
    25081 ccgatgggct gacaggccgt ggagtgatag tggctgtgat tgactcgggg atcgactttt
    25141 ttcatgagga ctttagaaat ccggatggaa ccacaaggct cttagagctg tgggatcagc
    25201 agctggaacg ggtgtttaca aggcaggaga tcaatgaggc cctgggacag gacagcagag
    25261 aaaaagggga ggccctggtt ccctccagag atttgagcgg gcatggaaca gctgtggctg
    25321 gaattgcggc gggaaacggc cgtgagagcg ggggaaccta ccgcggagcg gcgtatgaga
    25381 gcgagattct ggcggtccgc ctgggagttc cgggggaacg ctcctttccg agaaccacag
    25441 agctgatgcg ggcccttgac tatgtggtga atcgggcttt gttttatcag aagccggcag
    25501 cggtaaatct gagttttgga aatacgtacg gttcccacga cggaaccagc ctgctggaga
    25561 cgtacattga ccagctgtca aatcagtgga aaacggtgat tgtgacagga acgggcaacg
    25621 agggcagcag cagaggccac gcggcgggac ggtatgagat gggaaaggac acggagatag
    25681 agctttccgt ggccgagtac gagactggat ttggaatcca gctgtggaag ctgtatgcag
    25741 atattgtgga gatttctgtt gtcagtccag gcggtatctc taccggcgtt ctgagccgac
    25801 ggctgggggc ccagaggatt cccatgggca gtacagagct tctgatttat tatggaaagc
    25861 ccagtcccta tagccaggcc caggaaattt atctgaatct gcttcctgtg ggaagctacg
    25921 tccagagcgg aatctggaag atacggctga ctcccagaaa ggtggcggtc ggacagtacg
    25981 atctgtggct gccgggcgga ggaagcctga accgggctac ccggtttctc gtttcagatc
    26041 cagacacaac attgacgatt ccttctaccg cttcccgggt ggtttctgtg ggagcttacg
    26101 acgattctta cctgtcctac gctgattttt cggggagggg atacaccagg cttaacacca
    26161 gcgtgaagcc ggatctggct gcccccggag tggggattat ggctcccaga gcgggaggag
    26221 gctacgggcc ggtgacggga acctcctttg cggcgccttt tgtcagcgga agcgctgctc
    26281 tcatgatgga gtgggggatc gtcaggggaa acgatccgtt tctctacggg gagaaggtga
    26341 aggcttacct gatccgggga gccaggcccc ttcccggcga gaccgtttat ccgaaccagc
    26401 gtctggggtt cggcaggctg tgtctggagg acagttttcc agtttaacgg ccgcaaaaag
    26461 gcgcggcaaa gacaaaatat gacaaatttt atagaaaatt gataaaatat tcagaaataa
    26521 actctgttaa aacagatgaa aatatgatat aatggcaaga taatcgggaa agtttgtaaa
    26581 ttactgccaa tggtgataaa ggatgtgatt caatgaacat cagggagatg acagaacagt
    26641 gggaaacaga atatctgagc ccctatgcgt ctatgagcag aaacacgcgg ggacgggaga
    26701 gacaggagga gctttgcgat atacggccgg aataccagcg ggaccgggat cggattctcc
    26761 acagcaaggc cttccgcaga ctgaagcata agacgcaggt ctttttagat ccagagggag
    26821 atcactacag aaccaggctg acgcacaccc tggaggtgtc ccagattgcc aggaccattg
    26881 ccagagccct gaggctgaat gaagccctga cagaggccat tgccctggga cacgacctgg
    26941 ggcatacgcc cttcggccac gcgggggagg cggctttaaa ccggctggtg ccgggcggct
    27001 ttacccatgc cggacagggc gtccgggtgg tggagcttct ggaaaagcag ggacaggggc
    27061 tgaatctcac ctgggaggtg cgggacggca ttttaaacca cagaacctct ggaagcccgg
    27121 ccactctgga aggacatgtg gtgcggctgt ccgataagat tgcctatatt aaccatgata
    27181 ttgacgacgc gattcgggcg aaattgttta cagaggagga tctgccttct gagtacacag
    27241 acattttagg ccacagcgtc agagagcgat taaataccat gatccacgat ctcatctatc
    27301 agagcctgga ccgcccggag atcgccatgt cgccggggat ggaggcggct atgcacggcc
    27361 tgcggcggtg gatgtttgaa aacgtgtaca ggggaaagac agccagggcg gaggagggca
    27421 gggcccagca gctggtagtc agcctctatc actggtatat ggatcatccg gaccagcttc
    27481 cgcgggaata tctggatcgg atggagacca ggaaagaaga gctttcgaga actgtgtgcg
    27541 actatgttgc cgggatgacg gacgtgtttg ccattgaacg gtttaaggag ctgttcgtgc
    27601 ctaaatcatt caaggtatag aagcgggata tacaaaatag aagaagcaaa agaaagcagc
    27661 aggaggattt catgtactat ccggaggaag taatcgagga agtcagaacg agaaacgata
    27721 ttgtggatat catttccggc tatgtgaagc ttcagaaaaa gggaagcaat tatttcggac
    27781 tgtgtccgtt ccaccacgaa aaatcgcctt ccttttctgt ctcccagtcc aagcagatgt
    27841 accactgctt tggctgcgga gtcagcggga atgtgtttac ctttgtgatg gaatatgaaa
    27901 attatacgtt ccgggaggca gtggagcttt tggcagacag gagcggagtc aagcttccca
    27961 agatggaata ttcaaaggag gccaaggccc aggcggatct gagggccgcg ctgcttgaga
    28021 ttaataagat ggctgccaat tatttttact atcagctgaa gcagccgcag ggccagcagg
    28081 gctgccagta tctgatggga agagggctga cagaacagac catccgcagg tttgggctgg
    28141 gctattccaa taagaccagc aatgatttat accagttttt aagatccaag ggatacgagg
    28201 acagtattct gaaggaaacg ggccttgtga ccattgagga gcggggagcc agggataagt
    28261 tctggaaccg ggtgatgttc cctattatgg acgtcaataa ccgtgtcatt ggctttggcg
    28321 gcagggtgat gggggacggg gaacccaaat atctgaattc tcccgagacg aagctgtttg
    28381 acaagagccg caatctgtac gggctgaatt atgccaggct gtccagagag aaatttatcc
    28441 tgctctgcga gggctacatg gatgtgattg ccatgcacca ggccggcttt acgaatgccg
    28501 tggcttcgct gggaacggcc tttaccagcc agcatgcggc ccttttaaag cggtatacgg
    28561 atcaggtggt tctgacctat gacagcgacg gagccggggt caaggctgct ctcagggcga
    28621 ttcctatttt aaaatccgtg gggatgtcgg ttcgtgtgct gaacatgaga ccgtacaagg
    28681 acccagatga atttattaaa aatctggggc cggaggcttt cagacagcgg attgcggaag
    28741 ccagaaacag ctttttattc gagatcgaca ccatcagaca gcagtacagc atggaggatc
    28801 cggagcagaa gacggccttt tacaacgaga cggccagaaa gcttctggaa tttcccgagg
    28861 ccctggagcg tgataactac attcaggcag tggcaagaga gtattttatt aattatgaag
    28921 acttaaagcg tctggtgaac cagatgggca gccgttacgg cacggctctt ccgggaacac
    28981 aggctgccag ggagacggga atttcaggag agatttacgg agagaagccg aagaccttcc
    29041 agaagaaaaa ggatcgggag gagggaatcc gccagtcgga gagacttctg ctcacctggc
    29101 tgatcgagga tcccaggctg tttgacaaga ttcaggggat catagggccg gaggactttg
    29161 tgaagccgct gtaccggaga gctgcccaga tggtgttcga gggacatgaa aacggagaag
    29221 taagtccggc tgcgattttg aatcatttta ttgatgatga gggaaactat aaggaggtgg
    29281 cggctctgtt taacgccagc ttaaatgatt ccctgagcaa cgaggaacag aagaaagcgt
    29341 ttgccgatac agtgatgaag gtgaagaaaa gcagccttga ctatcagagc cggactgcct
    29401 ctgacttaaa tgaactgcag aggattatca gagagcaggc agaactggca aatatgcata
    29461 tttcgctgga ttagctccga atgcaggggc atctgcctgc gcgggatgcg ggggagaaaa
    29521 aagcagtaag cgatggaagg atggagaatt atggaagaaa agacactgac ctttgaagag
    29581 aagctggaga aacttctgga gctggcaagg aaaaagaaaa acgtgctgga acagaaagaa
    29641 atcatcgatt tcttccatgg cgaaatcctg agccctgagc agctggatca gattgacgaa
    29701 tacctggaaa acaataaggt ggacgtgctg gcccccgacg aggatctaga gatggaaccg
    29761 gaactctttt tggaggagga ggatctggag gaggaagaga tcgacgtcga tcatctggag
    29821 ctgtccatgc cggagggcgt aaatatcgag gatcccgtcc gtatgtatct gaaggagatt
    29881 ggaaaagtgc ctcttttgac gccggaggaa gagattgacc tggcgaagcg gatggagatg
    29941 ggggatgagt cggccaaaaa acggctggcg gaggccaatc tccgtctggt ggtcagcatt
    30001 gccaagcggt atgtgggaag aggaatgcag tttctggatc tgattcagga gggaaatctg
    30061 ggtctgatta aagcggtgga gaagtatgat tattccaagg gttttaaatt cagcacctac
    30121 gctacctggt ggatccgcca ggccatcacc cgatccatcg cagatcaggc ccgcaccatc
    30181 cggattcccg tccatatggt agagaccatt aaccggctga tccgcacctc cagacagctt
    30241 ctgcaggagc tgggccggga gcctctcccg gaggagctgg cgaagaagct ggatatgccg
    30301 gtggatcggg tgcgggagat tatgaagatt tcccaggatc cggtttccct ggaaactccc
    30361 ataggcgagg aggaggacag ccatctgggc gattttatcc aggatgagca cgttcagatt
    30421 ccggtagacg cggctaccta tactctgctt cacgagcagc tgatggaggt tttagatacg
    30481 ctgacagacc gggaacagaa ggtgctccgg ctccgcttcg gcctggacga cggaaggccc
    30541 agaaccctgg aggaggtagg ccgggaattc aatgtgacca gagagagaat ccgccagata
    30601 gaggcgaagg ctctcagaaa gctgcgccac cccagcagaa gcaggaagct gaaggactat
    30661 ctggactgat gggaagcgga gtaatcatag aagaaaggaa aaggacaaag agacagacga
    30721 tgaaattatc aaaaagactg gaaatgattg cctcttttgt aaagccgggc agcaggctgg
    30781 cagatatagg aaccgaccac ggctatattc ccattgccct gacagagagg ggggtgatcc
    30841 tctccgctct ggccatggac gtgaggaaag ggcctctcga gagagccaga gagcatatcg
    30901 gggaggctgg gctggctgag cagattgaga cgcggctttc cgacggactg gaaaagctca
    30961 aggcgggaga ggcggacacg gtggtgattg ccggaatggg cggagagctg gagatacata
    31021 tcctggagga gggatgccac atctgggaca gcgcggccca gtgggttctc tcgccccagt
    31081 ctgacctgga gcatgtaagg cggtatctgc tggagcatgg cttttccatt gacagggaag
    31141 ccatggtgaa ggaggatgga aaattttata cgattatgga cgtggctggc cctggccgga
    31201 gggacgcggc ggattgctcc ggctggaggg aaagcgacta tgtctacgga aaatacctga
    31261 tcgagacggc ggatccggtt ttaaaagagt tcctggagca ggagaagaaa actgtttcag
    31321 ggattttcaa ttctcttaac agcagagata cggacagctc taaaaaaagg gcaggagagc
    31381 taaagaagaa attagatctg atagaggagg cgcagtatga aatgcaggga aataattgaa
    31441 aaactgaatc agctggctcc agagcacatt gcctgcggct gggataatcc gggactgctg
    31501 gcaggccgca gagacaaggc ggtaaagcgg attctggcgg cggtggatgc ggacgacgct
    31561 gtggtggagg aagcgatcga gaaaggggcc gatatgcttc tgactcatca tcctctgatt
    31621 tttaagccgc tgaaaaaagt aaatgacgat gatttcatca gccgccgcat tatgaagctg
    31681 atacaggcgg atatctctta ttatacgatg cacaccaatt ttgacgcggc cccgggctgt
    31741 atgggagatc tggctgcaga ccggctgaag ctttcagagc gggagattct ggagcctatg
    31801 ggcttcatgg aggacggaag gccctttgga atcggctcag tgggatttct cccggaggag
    31861 atgacagtgc gggaagcggc agagtatgtt aagagagtat ttcagcttcc tttcgtaact
    31921 gtatatgggg atgacggagg aagccgcctg gtgaaaaaag cggctgtctg cccaggagcg
    31981 ggaggcagta ctctggaaaa cgctctggcg aagggcgccc aggtgtatat taccggagat
    32041 atgggccacc atacaggaat cgacgcggca gctcagggaa tggcggtgat tgatgccggc
    32101 cattttggaa ttgagcagat ttttatggat tttatggcgg agtacctttc tcaggctttt
    32161 cagggagaga tagaggttct aaaagcttcg cagggacttc caaactgtgt gatatagtga
    32221 cgtgcagagg gtagcagaaa caggagggat ggatatggca gctgtaatga tcgcagggga
    32281 gagacatgag tatccggagg gaacgcctta ccgcgtgata gcagaggatt ttcaggaaaa
    32341 agagcaggag gatattcttc tggtcagggc agacggaaag ctgagagagc ttcacaagga
    32401 gctgtccggg gactgcagcc tctcctttat cacagccgag gacagagaag gatggcagac
    32461 gtatcagaga agcgccgtat ttttaatgtt gaaggccttt tacgacgccg ctggaagaga
    32521 ctgcgtaaaa aaggtgacag tctgcttttc tgtggggcag ggactctata ttgaaccgga
    32581 gggggacttt gagctgaatg aggagcttct gaaggctgtg aaggacagaa tggaggagct
    32641 gagagaagcg cgtctcccca ttgtgaaaaa aagcctgaat acccaggaag ccgtagagca
    32701 cttccaccgc cacggcatgt acgacaagga gaagctgttc cggttcagaa gggcttccag
    32761 ggtgaacgtc tactccattg acaagtttga ggattatttc tatggctata tggtgcctga
    32821 cacaggatat atcaaatact ttgatttaac gctctatgaa aagggctttg tgcttctgct
    32881 gtcaaagaga agcgctccca ggaaaatcga gcctcttgct cccagaaaga agctgtttac
    32941 agtgcagcgg cagtcggaga gctggggaga gaagctgggg atttttgatg taggatcctt
    33001 aaacgaggcg atcacgcagg gcaggatgaa tgaaatcatt ctcatgcagg aggcgctgca
    33061 ggaaaagcag atcggggata ttgcagagca gattgcggcc aggccggatc ggaagctggt
    33121 catgattgcc ggcccgtctt catcgggaaa gacgacgttt tcccatcggc tttccattca
    33181 gatgcggggg ctgggcttga atccccaccc gatttctgtg gacaattact ttgtcaaccg
    33241 agtcaacagc cccagagacg aacagggaaa ctatgactat gaagcgctgg aatgcattga
    33301 tatggaacag ttcaatgcag atatggcgga tttgctggcg ggaaagacag tggagcttcc
    33361 ccagtacaat ttcgtgacag gagagaggga atataagggc gatttcatga cgctcagaaa
    33421 gggcgatatc ctggtgatag agggaatcca ctgcctgaac gaccgcctgt cctacgctct
    33481 tccaaaggag agtaagttta gaatctatat cagcgctctg acccagctga acattgacga
    33541 gcataaccgg atcccgacta cagacggaag acttctgcgc cgcatgatcc gggacgccag
    33601 aaccagagga tcttccgccc aggatacgat ccgcatgtgg gattctgtcc ggagaggcga
    33661 ggagagaaat attttcccat tccaggaaag cgcggacgtg atgtttaact ccgctctcct
    33721 gtatgagctg gcggtgctga agcagtatgc ggagcctctg ctctttggca tcccccagga
    33781 tgcgccggag tatgccgagg ccaagcggct gctgaaattc ctggattact tcctgggagt
    33841 gggcagcgag aacattcctc ataactccat gattcgggag ttcatcggag gaagctgttt
    33901 taaagtgtga ttatagattg tcattcaaag ctgcctccgt ctatacacga ggaaaacttt
    33961 tcttgttcca cttaaagtca ctgaaaagtt ttccccgcgt atttagagcg aattttttct
    34021 cctccataga caaaccgtga aaagtgtggt aaactagctt tcagttttcc gagtaagaca
    34081 aatggccgca gctgcatgtg ccgaaaggcc gcaggtgagg aaagtccggg cttcacaggg
    34141 caggatgcca gataacgtct ggcggaggcg actccaggga cagtgcaaca gaaataaacc
    34201 gcgggggctt tgcttcccgt aagggtggaa aggcagcgta agagactacc gcctggctgg
    34261 taacagacag ggcatatgta aaccccatcc gaagcaagac cgaacagaaa gcataaggcg
    34321 gcccgtctgc tttcgggtag gtcgctagag tctgccggcg acggcagaag tggatagatg
    34381 gccattcaac gacataaccc ggcttatcgt tttgctcgga aaacgtaaaa atgaatgtaa
    34441 gactgcagca aatgtgagag aagagcattt tctgcagttt ttttgtttta cagaaaagac
    34501 atttgaaaag gatgatgaaa atgagtacga ttggaattat ctgcgccggg gacagcgagc
    34561 tgcagcccta tttagatatg ctgccgttta aagagagcaa aaagaaggcc atgcttacct
    34621 tttatgagtg cgaatatcag acccacaggc tgattgccct ttacagcggc gtgtgcaagg
    34681 taaacggagc tctggcagcc cagattttaa ttgacgggta tcagccggat tttattttaa
    34741 atggaggaac ctgcggaggg cttgacgaga acgtggatat ttttgatacg attgtggcag
    34801 aacgatgcat ttaccatgat gtggcagagg acattctgac agattttcat ccctggatga
    34861 aagaaccctg gttcctgtca gatgaaaagc ttctgagggc ggcagaacga gcgcaggtac
    34921 ggcgtccttt gaggtttggg gctgtggcta cgggagaata tttcctgggg gccggcagca
    34981 gaagagagcg gcttttagag aagtatcccg aggtgctggc tgtggatatg gagacagccg
    35041 ccatcgccca tgcctgctat gtgaaccagg ttcccttcct ggctgtcaga acggtgacgg
    35101 ataacggcac tctgccggga atcggcgctt ttgaggcaaa cgtggaacag gcgtctgcca
    35161 tttcctgcca ggtctgcctg gaaatcatcg cggcatattc tgcgagatcc tgcgcctcat
    35221 catgcaggga gacagacagg aaccgatgcg gaatatatga gaaaacaggg aaaaagcaga
    35281 atttataaaa aagaggaaga gaacggtttc aggcagcttt cagcggagcc tggaaaacat
    35341 gtactcttcc tcttgcgttt attatgaatc ctttcagata ttcttttggc tatttctttt
    35401 cgtatttttc ctcacagtag aggcagcggt aaacctcttt cttctcatct gccaggcaga
    35461 atacatgagg aagctcctgc tcgatcgatg tgatgcagcg cggatttttg cagaaaatca
    35521 cattggtgat tttctggggc aggcggaggc tttttttctc cgcaattttg ctgtccttta
    35581 taatattgac agtgatgctg tggtcgatgt agcctaaaac gtccagatct accacatcca
    35641 gtccaccgtc gattttaatg atatcttttt tgcccatctt tttgcttctg gcatttttaa
    35701 taatggcagt ctggcagtcc agcttatcta agcccagctt aaaatagata tccatacctt
    35761 ttccggcctc gatgtgatcg aggacaatgc cttcttttaa tccgctgata tttaacatgg
    35821 tttttccacc tccagtaatg tcataatcag agccattctc acatacacgc cgtactgaac
    35881 ctggcggaag taggcggctc tcggatcgtc gtccacctct acggagatct cgttgactct
    35941 gggcagggga tgaaggacga acatgtcttc gcgggccagg gacattttct gcttgtccag
    36001 aatatagcag tccttcatgc ggatatagtc ctcctcattg aagaaacgct ccttctgaac
    36061 gcgtgtcatg tagagaatgt caagctcagg catggcctcg tccagatttt ccacttcacg
    36121 gtactcgatt cccttggcct gcagcacgtc ctcgcggata tagtccggaa tccgaagctc
    36181 cggcggagag atgagaacaa agcggatgcc ggtatagcgc accagggcgt taatcagcga
    36241 gtgaacggtg cggccgaact ttaagtcgcc gcagagtccc acagtcagat tgtcaaggcg
    36301 tccctttaaa gaacggatgg tcatcagatc agtcagagtc tgagtgggat gctgatggcc
    36361 gccgtcgcct gcattgatga caggaatgcc ggaatggacg gaagctacca tgggagcgcc
    36421 ctccttgggg tggcgcatgg cgcagatatc ggcatagcag gaaataacgc ggatggtgtc
    36481 ggaaacgctc tcgcccttgg cggcagagct ggaatccgcg gaagaaaagc caagtacgct
    36541 tccgcctaaa cggagcatgg cagactcgaa gcttaagcgt gttcttgtac tcggctcgta
    36601 aaacagagtg gctaattttt tgccgtcgca gacgtgggca tatttctgag gatgcttctc
    36661 aatatcgctt gccagatcga gaagcgcttc aatttcttca actgaaaaat ccagaggatt
    36721 taacaaatgt ctcatgtgtc tctcctttgc atgtattttt atttttatcc attatagcgg
    36781 atttgtgatg caatttccag actgtgtaag aaaaaagtaa gggaatttaa gaaaaatagg
    36841 ataggccttt cgggaattat taggtataat gaaacgagaa cagatagttg gaggaatgag
    36901 aatggcagaa gcgcaggaga cagagagcgg gaagaaaacc cctgtcatac aggtaaaaaa
    36961 cttatataag atttaccggg taggggagac gaaggtctat gccttaaacg gtgtggattt
    37021 caccatgtat aagggagagt tctgcgctat cgtgggaacc tccggttcag gaaaatccac
    37081 gcttttaaat atgctggcag gtctggagaa gcccactaag ggagagatta tcataagcgg
    37141 aaagcatatc gaaaagatga gagaggatca gctggtggcc ttccggcggg aacgggtggg
    37201 ctttattttc cagtcctaca accttttggg aaccatgaat gccatcgaaa atattgccct
    37261 tcctttgtct ttccagggaa ttggaaaaaa ggaacggctt cggcaggcgc agaaatatct
    37321 gaagctggta ggactttccc atgtggggga tcacatgccc aatcagatgt cgggaggaca
    37381 gcagcagagg gtgggcattg ccagggcgct ggtggtaaat cccaagatta tttttgccga
    37441 cgagcccacc ggaaacctgg attcgaaaac caccatggag gtactgaagc tgatgcagag
    37501 aattgtcagg gaacagcagc agacgctggt catggttacc cacgatgacc accttgctgc
    37561 ctatgcagac agaattttcc atattataga cggaaaaatc gtgaagatag aggaaaacca
    37621 ccattcagac gaggcgattt tcggagaagg gggagctgaa aggcagaagg aaacatcgga
    37681 cagggaggat gagagatgag aatgaaaagg ctgagacagg tactgattct gctgttagcc
    37741 gtctgcatga tgcttgcggg aactccattt ggagctttgg caggcatgat ggacatgacg
    37801 aatttcaacg atggcagaat cgaggtgacc aaggtcccga aaggaaaagc gggaggcaag
    37861 gtgaccatcc gcatgaagat tgtaaacgac gaggactccg acatggagga caccaccgtt
    37921 acactggtag gaggaaccag atacgatgac attttaaaca atgtgttcga gcaggacgag
    37981 gacgacggcg atgaggatga tgatgacgat gacaccatcc gggattacaa tacccagttc
    38041 ccctttgagg cggattcctc cacgtttgag gacaagaagg tgggaaccat ccggggacat
    38101 tcgtcaaaaa ccgtttccat tacctttcag ctgcgccgtg atctgcagcc aggctactac
    38161 caggcctttt tcgacctgaa cagcagcaga gaccacgaaa agacagtggg cgtcaatatc
    38221 tgggtatctg cgtcagacgg ctctgagtcg gatgaggaga cgatggacta tgatattacc
    38281 atcggcgaga accagtccac tccttacggc gtttacggag aagtgctgaa ttttggagtg
    38341 aatttgagaa acagcgggaa caggaagctg tacgacgtgc gcgtttccat gcagctggac
    38401 gcggccacag agaaattccc ctttgatatc aacgacggaa actatgacag aaaaatgggg
    38461 gatatggacg tgaatcagac cgtctccgtc ccctacagca tggcagtgcg tgaggacgcg
    38521 aaatcaggct tctatcccat tacatacaaa atttcctaca aggagacaga ggacggagac
    38581 ttcgaggagc cggtggataa aattctctat gtcagagtca agggagagga cgacgatgat
    38641 ctggaggcgg acgcagggga caacgagaga acgaaagcca gaattatcgt ggagagcttt
    38701 tccacggagc cggcggaggt ctacgcagga actccatttg ttctgaaaat cagaatgaag
    38761 aatgcttcgt cggacgtccc ggccaataat attttattta ccttcagctc agaggatacg
    38821 gataagaacc ctgtgttttc cacagagtcc ggatcctcca cagtggtggt aaacagtctg
    38881 gctccgggac agagtgcaga tttggagctt ttatttaatt cctctcctac ggcggagcag
    38941 aagtcttata ctatgtccat taaggaaaaa tatgacagcc cggagtttaa aaacgcggag
    39001 gaagaagtga agatttccat cccggtgaag cagcagccca gattcagcac cagcaccatt
    39061 gaggtgatgc cggagagcat cagcgtaggt tcggagacca acgtcatgtt tggaatcaat
    39121 aatacgggca aggtgcttct ctacaatgtg acggctgtgt ttgaggggga ttccatccag
    39181 aaaaccgacg cttatgtagg caacattgag cctggaaaga cgggcaatgt ggacgccatg
    39241 atttctggca tcgctcctac agctgacgac ggaaaaataa agattactat ttcctatgag
    39301 gatgaaaacg gagaggtgac ggaggtagag aaggagatga atctcctcgt taccgagaca
    39361 atggaggaac cggcggacat ggacgctatg gcggatatgg aggaaatgat gccggaggag
    39421 ccgtctgctt tcagtaaata taagtggctg attctgctgg gagccgtttc tgcagcagca
    39481 ggggggacgg cagtttaccg ccgcaggaaa gcgaagaaga aggcacagga ggaagaggat
    39541 atagacgatg agatttcttg atctgctcac catgagcgtc aataatctgc gccgcagaaa
    39601 gcttcggacc tttctgaccg ttctgggcgt agtcatcgga acggcctcga tcgtagtcat
    39661 ggtttccctg ggcatcggcc tgaataactt taccatggag accatcaagt cttccggaag
    39721 cctgactgcc attgagatct acaattacca gggaatgcag ggggatgaca agacagagga
    39781 ggatttcatt acagatgaaa cgatcaaaag cttttcccag attccccatg tgacctccgt
    39841 gtacccgatt ctgaacatca atgtgctgat gaagcagggg atttacgagg gctatgtgac
    39901 gatgatgggc gttcctctgg attatatgaa ggatattccg ctgggagccg gaaagctgcc
    39961 ctcccccaat gccgatatgc tggagatggt agtgggaaat atggtagcca gaaattttac
    40021 caactcgaag acaggaaagg gctactggga tacaggagag gatccggatg tagattttat
    40081 ggcccggccg gcgtttgtca tcttcgatat ggacgcctac taccagtcgc agtcaggagg
    40141 cgggggcggg gaggagcctg tgaagcctcc gaaaaaatat atgctgaata cgtccgccct
    40201 ggtagaggga ggtccggagg attataatga atacagctac agcgtttatg tggatttgaa
    40261 taagctgaag gagcagctga agcagatttt taagaagaat ccgattccgg gacagccggt
    40321 caataaaaag ggaaagccgt acaattactt cgtttacgag caggctgtgg tcaatgtgga
    40381 tgatatggaa aatgtgaagg aggttcagca gcagctgatt ggcatgggct tcgaggccag
    40441 cagccgtatg gactggctgg aatcctccca gaagcagtcc aacatggttc aggccgtgtt
    40501 aggcggaatc ggagccgtct ccctgttcgt agccgccatc ggaattgcca ataccatgat
    40561 gatgtccatt tacgagagaa ccaaggagat cggcgttctg aaggtgcttg gctgcgccat
    40621 gggcaatatc agaagcatgt ttctcataga agccgggttt atcggcttca tgggaggaat
    40681 catcgggctg cttctaagct atggagtatc cgggattgtg aaccgttttc tggctccggg
    40741 ccttacggac ggaatgacca gccggatatc catgatcccg ccgtggctgg ctctggctgc
    40801 tgtggtattt gccgtgttta tcggtatgct ggccggattt ttcccggctc agagagcgat
    40861 gaagctgtcg cctttagcgg ctatcagaaa tgaataatgc agtacggaaa ggctgggaaa
    40921 gcgtttctga atgtttcaga aacgttttcc cggcctttta actgttgcgc tccgcccagt
    40981 tgtgagttat gattataata gttagcaaac taatagttgc atagacaact gtaaggccgg
    41041 acggcagaag ggactggtat gcagatccgg cgcagaggaa caggagaggg agaaaagatg
    41101 gaactgtata tgcttttata ccgggcattt cacgctcaga gaaaacggct gcggccttat
    41161 atggcacaga ttggcctggc gccgggccag cctaaaattc tgcggtacgt gttaaaccac
    41221 gagggatgta tgcagaagga ggcggcggaa agctgcgaca ttgaaccggc aaccatcagc
    41281 cgcatgattg acaccctgga aaagggaggg cttgtaaggc gggtaattcc ggagaacaac
    41341 agaagggccg gcagcctgta tctcacagaa aagggagagg agagctaccg gctctgggag
    41401 gcccactgcc gggaaattga gaaggaaatg ctggtcggct tttccgaggg ggagaagaaa
    41461 caggtggcgg attacctgag ccgcatttac aggaatttaa gcggccggga cgctctttaa
    41521 agaggaggag agaagctttg gaggatttaa aacggatttt taagtttatg aaaccctgcc
    41581 ggagagaatt ctttctggcg gtgatgtttg tcataatcga ggccagcttt gagctgacga
    41641 ttcccatgct gatggcagat atgatcgacg tgggagtggc tgacagggac atggattaca
    41701 ttgtggccag aggactgacc atgatggcct gcgctctgtt cgccctggtt acaggccttc
    41761 tgtacgccag attttcggcc agagcggcca acggctttgg agccgctctg cgggaggcgg
    41821 agtatcggaa ggttcaggaa tattcctttg aaaatctgga acactttgag acctcgtctc
    41881 tgatcaccag gatgacggca gacgtgacgg tgatgcagaa taccataagc ggaggcctga
    41941 ggcccttaac cagaagcccc attatgcttt taatgggact tggcatgacg ttttatctga
    42001 ataaaaaact ggtgctggtg tttgccgtct gcattcctgt gctggccttt attctgtacc
    42061 acatcgtcag ccgcgtggcc cccatgtacg gcaggctcca gaaggccatg gaccaggtca
    42121 atgcagttgt ccaggagaat ttaaacgcag tccgggtagt gaaggccttt gtgcggggcg
    42181 aatatgagga ggagaaattt gcgcaggtca acgacaattt aagggagacc agccagacca
    42241 cgttccacta cgcggtgatg aatcttccgg cctttcagat cgtcatgtat acggcgattg
    42301 tgctgattct gtggttcgga ggaagaatga cgcagatcgg cggcatgcag gtgggagagc
    42361 tgacaggctt tctcagctat gtgcagcaga ttatcaactc tttaatgatg ttttccggcg
    42421 ttttcctgat gctgacacga tccctggcca gcgctaagag aatcggagag gtatttgacg
    42481 aaccgttaaa cctggcggac ggagagggag ccagccagca ggtggaatgc ggttccgtgg
    42541 actttgacca tgtatttttc aagtataaaa aagaggcgga ggagtatgtg ctctcagacg
    42601 tcagccttca cataaaagcc ggggagacgg tgggcattat cggaggaacc ggttctgcca
    42661 agagcacgct ggtacagctg attccccgtc tctatgatat tacgtcagga agcctgaagg
    42721 taggcggaaa ggatattaaa acgtataccc tggaacatct gagagacgcg gtgggaattg
    42781 tgctccagaa aaatctgctg ttttccggca cgatccgtga aaatttaaag tggggaaatc
    42841 ctgatgcaga cgaggaggag cttcagtggg cctgccgggc ggcctgcgcc gacgaattta
    42901 tcagccggtt tccggaaggg tacgacacag atctgggaca gggaggcgtc aatgtatccg
    42961 gcggccagaa gcagaggctg tgcattgcca gaacgctgct aaagcatccg aaggtgttga
    43021 tttttgacga ttccaccagc gctgtggaca cggctactga cgttaaaatc agggcagagc
    43081 tggcgaagct ttccgacatg acgaaaatta tcattgccca gagagtgtcc tcggtaatgg
    43141 atgcagatca gattgtgatt ctggaggacg gaaacatcca cgcagtggga aagcacagag
    43201 aacttttgga gacagatcca atctatcagg aactttacta ttcgcagcag aagggaggag
    43261 aggaagatgg cgagacagtt taatggaaaa cgtccaaaga atttaaagcg cacggtatta
    43321 aagcttatgg gctacatggg aaatcataag tttctgctcc ttctggtggc tgtgttggtc
    43381 tctgtcagcg cttcggcggg acttgcggga acctacatgc tgaagcccat tgtcaatcag
    43441 tacattgtgc cgggagacgt ggaaggcctg ttccgggcgg tggcgtttac aggaatgatc
    43501 tatctgtgcg gcgtggccgc agcctatggc tacacccaga ctatggtggt ggcggcccag
    43561 aagattattt atgaaatcag gcgggatctg tttaaccaca ttcagtccct gccgctgaaa
    43621 tactttgaca ccagaaccca cggcgatatt atgagccgct ttaccaacga tgtggatacg
    43681 atttccgacg ccttcaataa cagctttgcc atgattgtcc agagctttat ccagattgtg
    43741 ggaaccctca cgttgatttt tgtgctgaac tggcgtctgt ccctgattgt atttgcctgc
    43801 tatattctga tgttttccta cattcgctat agtggaaaaa agagcaaata ttactttaat
    43861 tttcagcaga agtatctggg agaattgaac ggctttattg aggagatgac agccggccag
    43921 aaggtagtga aggtatttaa ccacgagcag gcgggaatcg aggctttccg ccagaaaaac
    43981 agccagctga gagaggcggc taccagcgcg ctgacttact ctggaagcat ggttccggtg
    44041 atcgtcagca tctcctatgt gaattttgcc attgtggcca tggtgggcgg ctatatggcc
    44101 ttaaagggct ggacggatgt gggaagcctt accagctatc ttgtctttgt ccgccagacg
    44161 gccatgccta ttaaccagtt taccctccag tccaatttta tgctggccgc catggccggt
    44221 gcagagcgga tctttgaagc tatggatgag gagccggagg tcgatgaggg aaccgtcact
    44281 ctggtaaaca gaaaagactg tccggacgga accattgagg aatctgggga acggacgggg
    44341 ctttgggcct ggaaggacag gagggcagac ggaacggtgc agctgattcc cctgcgggga
    44401 gatgtgcagt ttgaacatgt gaactttgga tatgaaccgg gacaccccat tctcaaggac
    44461 atcagccttt atgcgaagcc ggggcagaag attgcctttg taggctctac aggggctgga
    44521 aaaaccacca tcaccaatct gatcaaccgg ttttacgata tagacggagg gcggctcacc
    44581 tacgacggca ttgacgtggg caggatcaaa aaggatgatc tgcggcattc cctgggaatt
    44641 gtgctgcagg atacccacct gtttacagga accatagagg acaacatccg ctacggccgc
    44701 ctggacgctt ccggggagga ggtgagggcg gctgccaggc tggccaacgc cgattccttt
    44761 atccggcggc tgccgaaagg ctacgatact atggtgacgg cggacggagg aaatctctcc
    44821 cagggccaga ggcagctgtt agccattgcc agagcagcgg tggcagatcc gccggttctg
    44881 atcctggacg aggccaccag ctccattgac accagaacgg aacggctgat tgagaaggga
    44941 atggatcggc tgatggaggg aaggacggtg tttgtcattg cccacaggct gtctacagta
    45001 cgcaactccg atgcgattat ggtactggag caggggcgga tcatcgagag aggaaatcac
    45061 caggagctga tcgcccagag aggagaatac taccagcttt acacaggcat gttcgagctg
    45121 tcctagcatc ctgaaggcgg ctccgcttga tacagaggca cagccctgcg gcgggatgga
    45181 gatgaaaaat taagataatg aaagaatagc gtaagatttt gtttatacag acggcagggg
    45241 actgtggtaa aataaaagaa aagccagaaa aagaccagta tgctttttcg ggaaaggggg
    45301 atctgtatga aaaaggagat tgcgctgaaa ccgccgtgca gggagtatga cgtgcagggg
    45361 atggagagct ggctgcagta tcagagcctt tcgggaaacc gcctgtttga tacggcgggg
    45421 agaacctttt actttcagga ggcggagccg aaaaagctgg ttttccgcct ggagcctcac
    45481 ggaaaaaaac agatatctga ggaacagaag gaagactgga aaaagcgtgg ctggagctat
    45541 gcggcctcct accgtcgtct ttacgatatt ttcttttctg agacagagga gagagacgag
    45601 gcggaggcgc tggcctcttc ccagagcgtg ggacttcagt tcctggatca gcggtttgga
    45661 agctggagac ttttggggat ttttttcata gcgctggcgg cggtattatg ctggctgtgc
    45721 tggaaaaatg gagacacgat ccttcaattt ttatatggaa atggaccgtt tgcagttctc
    45781 ctgctggctg cattcacgat gttctggctt tctgcatgga tcatgggagc atggatcagg
    45841 ggacagacag aggcgctgaa ggcaggaagg cccatgccgg aggaggatta ccagggttcc
    45901 atgagaaagg caggaaaatt tttaaaggtt ctgcagatat tctggactgg aaccgtcctg
    45961 ctggcgcttg tgatgaatct ctccggatcc tccggcagtc tgggggagac ggctggccgc
    46021 agcgattttc taagccttgc caaaatggaa ggagagtact atactccggc tttagaacag
    46081 ggggaaccga caggacagag ctacaggaca gaaagaaatc ccctggtgaa gaaaaacctc
    46141 tatgtagaac agtcaggcta taaatttcag actcaggagg agctggagcg gtatgcagag
    46201 gctggaatgt cagatgaaat cgcccctgcg agggagaaag cccgggaaca ggcggcagcg
    46261 ccgggcattc ctgtaaagct ggagctctat ctctatgaga cgaggcggga ggaggatgca
    46321 gaaaagctgg tcaatcaggt ctgctcaaaa tacatgggaa tttcccagaa agcagatctg
    46381 taccagaatg gaatttatga gtttgacgac gccagcgtaa ttcaaatgga agaaaacagg
    46441 cagattgtct gcgccagagg aggaaaaaca gctaccatcc tcatctatga gggagactta
    46501 gacatgaacg gccagctgga gtacatttcc caggctgtgc tggccgggaa ggacagctgg
    46561 aaggaggagc tggcgaatta aacaaataaa ccaacctgtg ttccggaagg gaaaagcact
    46621 tgaaaagccg tcttcgcata agatacatta acgtatctga aaggcggctt tttttgaata
    46681 catttcccaa accattatcg gcagaagaag aacggacctg tctggagcag tacagaaacg
    46741 gaagcgagga agcaaaagcc gttctgatag agaggaattt aaggctggtg gcccatgtgg
    46801 tcaagaaata ccagtacaca gattacgaga cagaagatct tctgtctgta ggaaccatag
    46861 ggcttattaa agcagtaaat acgtttaggg cagatcgtgg ttccaggctg gctacctatg
    46921 cggccaaatg cgtagagaat gctatcctat cgccagggag tcagagacag gcagcgtttt
    46981 attaatcggc cggcggatgc agggcagcct cgatgactgc atccagaagc gcttttttct
    47041 gttcctggga ctttgcagag gactggatga tgtggagtac cgcgtcagcg tgaatctggg
    47101 cggcttttct ggccagctca agctttcctt tgtcagtgga aggttcatgg atcacaatgc
    47161 gaagcggaat attttttcct gccatagata catctctttc ccagcgccag aaaacagaga
    47221 cctgcagttt tgctttctga cgctgtattt atttttctgc tgcagtagtc tatgagagaa
    47281 ggccggtatt ctattcacat cagaacaaaa tttgagtgaa atgtgatgat gtcacagaaa
    47341 aagagtccaa ttccctgtat agtaaaacca taataataca ggaggtgctc ttatgagatt
    47401 aaaagataaa gtcgccatta ttacaggagg aagcagggga attggatttg ctgctgcaga
    47461 gaaatttctg gaggagggag cgtctgtcat tattacagcc agctcccagg ccacagcaga
    47521 aggagctgta tcgaaattga aagaaaagta tccggaagcc gcagtggctg gaatctggcc
    47581 gaatctggcc agcctggaat cagtccgcgc cgcgttcaga gaggtggagg agcggttcgg
    47641 aggcgtagac attctggtaa acaacgcagg cgtttctgaa agtacgccgt ttgcagagta
    47701 tacagaggaa atttttaata aggtgatgga cttaaatgtg aaaggcgtct tccacgcatc
    47761 cagagcagtg gtggaatcca tgataaaaag aggcggcgga gtaattcttt ctacatcctc
    47821 catggtcagc atttccggcc agcccagcgg gtttgcctat ccggcatcca agtttgcagt
    47881 aaacggcctg actgtatccc tggcgagaga gctgggaccg aagggaatcc gggttaatgc
    47941 tgtggcccct ggaattatag agacagatat gatgagggca gtgccgaaag aagtgctcga
    48001 tcccatgatt gaaaaaatcc ctctgcgccg tctgggacgt ccggaggaca ttgccaatgc
    48061 cttcgcattt ctggcctcag atgaggcttc ctatatcaca ggcgcagtgc tgagtgtaga
    48121 cggcatggcg agagcctagg acagagagca gaaaaaataa gagtgacagg aaaccgggcc
    48181 gcggaagaat atgccgcggc ctgggaggag cgaaaatgga acggaaacga aaaaaggctc
    48241 tggtcgatca gaggctgtgc gtggcctgcg gctgctgtgt gaaagcctgc cctgtacagg
    48301 cggtgcaggt ggtgaaaggg attatggcaa aggtagactg gggacgatgc gtggggtgcg
    48361 gcagatgtgt gaaggaatgt ccggccagcg tgatttccct gcaggaggta aaagcatgaa
    48421 aaaacagtgg tatgattatc tgtgggtgct gtcccttgcc tacctgatac tgggattttt
    48481 taatatttta tttgcgtggc tggggttaat ctgcttcttt cttccgctga ttatctccct
    48541 ttcaaagggg acgaagggct actgtaacca gtactgcgga aggggacagc tgtttggaat
    48601 tctgggaggc agactggggc tttccagaaa acgtgatatg cctgggtgga tgaaaggaaa
    48661 aaaattccgc tatggatttc tcgtcttttt tctcctgatg tttgcccaga tgctatggaa
    48721 tacctatctg gtatttgcgg gagcccagga tttaaagcag gtggtgacgc ttctgtggac
    48781 ctggaaactg ccctggcact gggcatacca cggcacgctg tttcatgagg gcatggccca
    48841 gtttgccttc ggcttttaca gtgtaatgct gacctccaca gttctgggaa tttttatgat
    48901 gactcttttt aaacccagaa gctggtgtgt aatctgcccg atgggaacca tgacccagat
    48961 gatctgcagg gtaaagaacc gctagaggaa ggtctttgga gctgcccaga attcttctta
    49021 tgtattctga agcgcgcgca gctttttctc atccaggaca gccaccatgc cccgggacag
    49081 acgtaccatg ccctcgttct gaaaatagcg gagcattctg gtgataacct cccggtggga
    49141 ccccagatgg ttggcaatgg tttcatgggt gatttttaat tcataggttc cctcaatagc
    49201 ggcctcctcc agcaggaagg ccgctacgcg cttgtcaagg ctcttccaca taatctgctc
    49261 aatcagccac atcacgtcag aaaaccggga agccatcaat tcgttggtat agttggctgc
    49321 cggcgcagat tcattcataa tatttttgta tacatctgcc ggaatgatcc acagctcagt
    49381 atctttttcc gcttcaatta taatctcaaa ctgaatagag cgcatgatgc aggatgcgga
    49441 aaaaaggcac atatccatgt caaacagacg gtaaagggtg atttccctcc cttcatcgga
    49501 gagaatgtag gcccggagct gacctgattt caaaaggagc agaccggtgc agtctgcgct
    49561 tccgttatgg acgaccgtac ccttggaaac ccggcttgtc atgagacttc caaggagtct
    49621 gtcctgctgg tttttagtta attggttcca aattggaaaa ctgttttgaa agtccatctg
    49681 tttcctcctt ctctgaaacc agtataaaac ggaggagggg ttctgtcaat ttgaaggtga
    49741 ttatatcacg gaagaggaca ggaaaatttt gtatactgat aacaaataaa agaagggagc
    49801 tgacgtttat gaaggctatg gagataaaca gagaacagtt tgaacagatg gtgaatgggg
    49861 aaaaagcggt attgattgat ttttgggcgc cttggtgcgg ctactgcaga agactggggc
    49921 cggcatatga aaaaattgca gaagaatata atggcggcgg ccttctgaca gttggaaaag
    49981 ttaatattga cgaagagaaa gaattagccg agaaggagaa aatagaggta attcctacat
    50041 tggtgcttta caaaaacgga acagcagtgg actcgattgt agcgccggaa tcaaaagcca
    50101 tgattgaggc gttcattgag caggcgctga agaaataggg acaggaggaa gggctatgaa
    50161 cacagagcgg atttatgata tgctggttat tggaggaggg ccggccggct atacggctgc
    50221 cctctatggg acgagagcag gctttgatac tctcgtatta gaaaagctgt cggcaggagg
    50281 ccagatggcc ctgacgcacc agattgataa ttatcccgga tttgatgaag ggatcgacgg
    50341 atttgaactg gcagaaaaaa tgcagaggca ggcagagcgg ttcggggcga agacggagta
    50401 tgctgaagta caaaaactgg atttgacggc agaacccaag aaagtggaaa caagtgaagg
    50461 gatattttat ggaaagacgg tggtctttgc agctggggcg gctcccagaa agctgggaat
    50521 agagaaggaa gatgagctga taggacgagg agtcgcctac tgtgctgcct gcgacggaat
    50581 gtttttcaag ggaaaaacgg tggcagtagt gggaggcgga aattcagccg ctgcagacgc
    50641 tatgattctc agccgcattg ccaaaaaagt tctgctgatt cacagaagag acacgcttcg
    50701 ggctacgaaa atctatcatg agcctttgat ggcagcagaa aatatcgagt ttcactggaa
    50761 cagtgaagtg acagaacttc tctcgggaga aaaactgaca gggctcagat tgagaaatgc
    50821 cgttacaggc gagtcggagc aggtggagtg tgacggcgta tttatcagcg taggaaggac
    50881 accttccaca gaattggtgg gagggcagct gcatttggat ccggccggat atatagtggc
    50941 gggagaaacg acagagacaa acattcccgg cgtttatgct gtgggagacg taaggacaaa
    51001 acgccttcgc cagataattt cggcagcggc agatggagct gcggcagctc acatggcaga
    51061 agagcatctg gcagatcgcg tgtaggatac atgcagcaga ggataccagg ttcactttcg
    51121 ggaagccgga tgatataata gaagaaagta tatcaccgac tggcgcagga gatcagatat
    51181 gagaaaaaat gaagactgca ttgctgtgta ttcccggaag tcaaaattta caggaaaggg
    51241 ggagagcgtt cagaatcagg aagagctctg cagagagtac gtccgggttc actatgggga
    51301 agatgcgctg aaccgtttaa tcttgtatga ggacgaaggc ttttcaggcg gcgatttgaa
    51361 ccgtccaggc tttaagaaca tgatggacgc tgccagaaag aaacggtttc aggcgctgat
    51421 tgtctaccga ctggatcgaa tcagccggaa tatcagcgac tttgcagggc tcattgaaga
    51481 attgacccgt ctggacattg attttgtttc gattaaggag cagtttgaca ctggaactcc
    51541 catgggaagg gccatgatgt atatagcgtc cgtattttcc cagctggaaa gagagacgat
    51601 tgcggagcgg atccgtgaca atatgcacga gctcgccaag acagggcggt ggctgggggg
    51661 cacgactccc accggttatg cttcggagac agtggaaagt gtttcgccag gcggaaagac
    51721 gaagcgggcc tgcaggctga ggctgatacc ggaggaagcg gacaaagtaa ggctgattta
    51781 cagcctgtat ctggagctcg attccctggc ggggacggag gcccgtttaa tgcagctggg
    51841 gattcagacg aaaaatggcc gatcctttac gcgtttttcc atccggggaa ttctgcagaa
    51901 tcccgtttac ctgacggccg atctggaagc ttatgagtat tttgagcaga gcggatccga
    51961 aatcttctct gaaaaagagg cctttgacgg cgcccatgga atgatggttt ataatcggac
    52021 caggcaggag aaagggagaa ccacaaagct ccttccgccc ggtcagtgga ttgtggctgt
    52081 gggagaccat cccggcctga tacctggcgg caggtggact gcagtccaga aatcattgga
    52141 gcagaacaag ataaaatctt atcggaaacc gagaaagaat gaggcgctgg caacgggtct
    52201 tttgttttgc agctgcggaa gccggatgta tcccaagctg gggcggagga ggaagacggg
    52261 agacggcagg ccctacgcct atgtgtgcag gacgaaggag cgaagccaga ggcaggcgtg
    52321 cgcggcagat aatgcgagag gagaggagct ggacgcggct cttacagaat tgacaggaag
    52381 cctgaaggag gataaagaat gttttctcag ccttctgaga cagggccgcc gtttctgcct
    52441 gtccggtgag agcggggttc agatccggct ttctgcggcg aagcgggaga gagaggaaat
    52501 agagaggaag cagagaggac tggcagattc cctggcaatg tttcaggaac aggaggcgaa
    52561 agaggaagcc gttcgtcata tggaggagct gggacgcaga aggcgggagc tggacggaga
    52621 gatttggcat ctgaaaacca tcctgtaccg ggaaatcttg tctgattcag aaatccggga
    52681 aaaaggcaga agcctttctg agcttgcagg cattatgggc gttatggccg cagagcagaa
    52741 aagagcggtt ctaaacgccc tgatccagcg gatcatatgg gacgaaaaca cggcttatgt
    52801 gatccttaaa ggagtctcgg atgaagagct ctgccagtat gagaggcttg aagcgcatcc
    52861 tcctgtctgc ccggctgacg ctttgggggg aggatagcaa atgagatttt gatgatgctt
    52921 cgcgccggcc gaaagagagc cagagacgtg tcactctacg atacaatcgg aacggataag
    52981 gacggagaga ccgtcagcct gatggacgtt ctggaggcgg acgaaatcca ggctctggat
    53041 acgattatca tggagcagga cgtgaaggag ctttaccaga catatgagac ctgtttaaag
    53101 gatacagaaa agcaggtaat ccgtatgcgg tacggcctgt tcggatccag agagcatacc
    53161 cagagagagg tggcggccgt tctgggaatt tcacgttcct atgtgagccg cattgaaaaa
    53221 cgggcggttg aaaaactcag ggaggcgttc tagcctccct gcgcaggaga gaatcttgac
    53281 tttttttcag gctgctggta tgataattgg tggttagtaa gaactaacca ttataaaaat
    53341 agaaaaaagg cgcatgataa agacacaaaa ggaggaataa gtatgtcatt aattggaaaa
    53401 gaaatcagtg aatttaaggt acaggcctat cgaaacgggg cgtttcagga gattagcaag
    53461 agagacgtgc tgggaaaatg gagcgtgttt ttcttctatc cggcagattt tacctttgtc
    53521 tgtcccacag aacttgcaga tttggcggat aagtatgaag agttccagga cgcgggatgc
    53581 gagatttaca gcgtttcctg cgatacccac tatgtccaca aggcatggca tgacgcttcc
    53641 gagacgattc aaaagattca ttatccaatg ctggcggatc cgacaggcgc tctggccagg
    53701 gactttgacg ttatgattga agacgaggga gtggctgaga gaggaagctt cattgtgaat
    53761 ccggagggaa aaatcgtagc ttacgaggtg actgcgggaa atgtgggacg caacgcagac
    53821 gagctgttca gaagagtaca ggcctctcag tttgtggcgg aacacggaga tcaggtctgc
    53881 ccggccaaat ggcagccagg tgaggagacg ctaaagccca gtcttgattt ggtaggcctt
    53941 ctgtaacaga gcagaagaaa ggaaatgtga tgaagcattt gaaaatcgaa caggtaatcg
    54001 gaagagaaat cattgattcc agaggaaacc ccacagtgga agcggaggtt attctggagg
    54061 gaggcgtttc ggccagagcg gccgctccca gcggagcttc taccggagaa tttgaggcat
    54121 tggaacttcg ggatcaggat ccaggcagat ttttgggaaa aggagtttta aaggctgtgg
    54181 aggctgtcaa tacagtgatc agccggactc tttgcggaat ggatgcctcc gatatccacg
    54241 cagcagacca ggcgatgatt caggccgacg gcacagaaga caagtccagg ctgggagcca
    54301 acgccattct ggcagtttcc attgcctgcg ccagggcggc ggcagcagct ttggaaattc
    54361 ccctgtatcg gtttctggga ggcgtaaacg gcatctgcct tccagttccc atgatgaaca
    54421 ttttaaatgg aggcgcgcac gcgtctaata ctgtagacgt tcaggaattt atgattatgc
    54481 cggcaggggc agacagcttc cgggaaggac tcaggcagtc tgcggaggta tttcatgccc
    54541 ttcgcgccct cttgagcgag aagaagctgg ccgtctcagt gggagacgag ggaggctttg
    54601 ccccgaatct gtccagcgat gaggaagcct tcgagtatat tatggaggcg gtgagacggg
    54661 caggctatga gccgggaaag gattttgtct ttgccatgga tgcggcggcc agcgagtgga
    54721 agagcggtaa aaagggagag tacgtgctcc cgaaaagcgg ccggcgcttt acgtctgcag
    54781 agcttgtggc tcactgggag gagctggcgg acaagtatcc gatctgttcg attgaagacg
    54841 gccttgacga ggaggactgg gagggctggc agatgatgac agagcggctg ggaggcagaa
    54901 tccagctggt gggggacgat ctgtttgtca ccaacacggc gcggctccga aaaggcgttt
    54961 ctctgggctg cggcaattcc atcctcatta agctgaacca gataggaacg gtttctgaga
    55021 cgctggacgc tgtgagggag gctcacaggg ccggttatac ggcggttgtc tcccaccgtt
    55081 ccggagagac ggaggatacg acaatcgccg atctggcggt agcgcttaac acctgccaga
    55141 tcaaaacggg agcgcccagc agaagcgaga ggactgcgaa atacaaccag cttttaagaa
    55201 ttgaggagga gctgggagga gcggccgttt acccgggctt tggagcgttt ggctttacaa
    55261 gaaattttgt gtaattttga acaaagtttt acggaaattg cattgtattg gcggcggata
    55321 acagatataa tagactgaaa cactgagcat aggaggaata tgttatgtct attttagtta
    55381 caggaggagc cggctacatc ggaagccata cctgtcttga actgttaaag gcaggctacg
    55441 aagtagtagt ggctgacaat ctttgcaatt ccagtgagga agccgtaaga cgcgtagaga
    55501 agatcgcggg aaaaccggtg aaattttatc aggcggacat tctggaccgc gaggccctca
    55561 ataaaatttt tgatacagaa gaaatcgatt ctgtcattca tttcgcagga ctgaaggcag
    55621 taggcgagtc tgtggcaaag ccgctggagt actatcataa taacattaca ggcaccctga
    55681 tcctgtgcga tgtgatgaga aatcatggag tcaagaatat tgtattcagc tcctccgcca
    55741 ctgtatatgg agatcctgct ttcgtgccga ttacagagga ctgcccgaag ggccagatta
    55801 ccaatccgta cggccagacc aagagcatgc tggagcagat tctcacagat ttccatgtgg
    55861 ctgatccgga gtggaacgtg gttctgctgc gctatttcaa tccaatcgga gctcatgaga
    55921 gcggcctgat cggagaggat ccgaagggta tccccaacaa tctggttccc tatattgcgc
    55981 aggtggcagt gggcaagctg cagtgtctgg gcgtatttgg aaacgattat ccgactcatg
    56041 acggtacagg cgtccgcgac tatatccatg tagtggatct ggcagtcgga catgtgaagg
    56101 ccttaaagaa gattgaggag aaggcaggcg tgtgcatcta caacctggga acaggaaagg
    56161 gctacagcgt tctcgacgta gtgaaagcct atgagaaggc ctgcggcagg gagattaaat
    56221 acgaaattaa gcccagaaga ccaggcgata tcgcaacctg ctacgcggat gcttctaaag
    56281 ccagagagga attaggctgg gaggcagaac ggggcatcga ggagatgtgc gcagattcct
    56341 ggcgctggca gtcggcaaat ccagacggat acagaagcta atttgaaaaa gtttaaataa
    56401 cgatttagaa acaggccttt ttcagcggca ccgctgggag gggcctgttt tttgccttta
    56461 tggctttctc ctgctgctcc tatgagaact gctgccgaac tgaaatatga agacgggagg
    56521 agaagggaac tgtccgtcat gcggacgcgc gccgagcata gaagaaaaca gaacatatat
    56581 tcgaaaatgc ttgcggtttc tccggaactg tgatagaatc agaacaaacg ttctatctat
    56641 tttcttatgg aggagaaaca gatgctgata caggaaaatc ttggaataca ggaaaagctg
    56701 agaattcttt cagacgcagc aaagtatgac gcggcctgca cgtccagcgg agtggacaga
    56761 aaggggaagc aggggcagct gggcagcgcc cacgaggcgg ggatctgcca tagcttttct
    56821 gcggacggac ggtgcatttc tcttctcaaa attctgctta ccaacgagtg cgtttacgac
    56881 tgcaaatatt gtattaaccg ccggtctaac gatacgctgc gcacggcctt tacgccggag
    56941 gaggtgtgca ggctgacgat ggagttttac agaagaaatt atattgaggg tttattttta
    57001 agttcgggaa tccaggattc cccggatcac acgatggagc agatgctggc tgtggcaaaa
    57061 agcctccgcc tggagcacaa attccagggg tacatccatt tgaaggcgat tccgggcgca
    57121 tcgccggaac tggtggaagc ggccggattt tttgccgacc gcatgagcgt aaatttagag
    57181 cttcccactg cggacggcct gagaaagctg gcccccggga agacaagaga gaagatcctg
    57241 actccgatgc ggcagattca gaaagggatc gtaaaacaga tcgctcagga ggggcttctg
    57301 gaaaaaaagg gactgtcgtc tgcccttctt tctgattccg gccggagctt ttccggcagt
    57361 ctgcctgact ttggagaaaa gggcagaaga gaaagcagaa cgagccccag agtcattccc
    57421 ggcaggtctt cctatggaaa ttacgggctg ggaaggagtg cgtcaggcag atcggtattt
    57481 gttcctggcg gccagagcac gcagattatc gtgggggcta cgccggaaag cgatttccag
    57541 atggtttctg tcgccgaggc cctgtaccag aattttggcc tgaagagagt cttttattcg
    57601 gcctttgttc cggtcagcga cgacagcagc cttcctgctc tgcctggagg accgccgctt
    57661 ctgagagaac acagattgta tcaggcagac tggctgatgc gctattatgg atttcaagct
    57721 tcagagctgc tgtctgaaga aaaaccgaat tttaatgtgc tcttagatcc gaagtgcgac
    57781 tgggcagtga ggaacctggg ccgatttccg gtggaagtta accgggcgcc gtacggagag
    57841 cttttaagag ttcctggaat tggcgtgaag tcggcagtca gaattgtgga agccaggaag
    57901 ggaacggttc tccggtttga ggatttgaag aaaatgggag ttgtcatgaa gcgggccgtc
    57961 tactttatca cctgctccgg gaggatgatg catccagtcc ggatggatga ggattttatt
    58021 acaggatgca tgattggcga ggagaggaga aaggtctggg agctggaaca gaaagatacg
    58081 taccgtcagc tgtctttgtt tgatgatttt catatgcaga cagaacctcc ggcagaagag
    58141 agggcagctc ttttgacggg acagctgtag gaagacaggg agagaagaga tgacaatttt
    58201 tgtatgcaaa gatgaatttg acagcattct atgcggagtg tacgacgcct ggatgagcgg
    58261 cctgggatat gaaaacgtca ggcttataac caggacagag cagcagaatc agacgatgca
    58321 gatgtttgca gagtacagag aggcagaaga agcttcctgg aagataaaaa agacagccga
    58381 ggcaatacga agaaagattt cacaggaggc ctatgcgtgg atttatagag cgtctctcag
    58441 cagagaaaca gacaaagcgg ataaaatttt ccgttttctg gccaggggct ttcagtttgg
    58501 gcccagaacc gtcaaaatgc tgaaagatcc agacgtatat gaagtgttcc ggatgaatcg
    58561 ccaggtggcc aatgaggctc atctgctgac agggtttctg cgcttttctg aactgcctgt
    58621 ggggcttctg gcagcagtga tggggcctga gaaccatgtt ctcagccttg tggcagatca
    58681 ttttgcagag agaatgtcag gggagcgctg gcttattttg gatcaaaaca gaggaagcgc
    58741 ggcgcttcat gagccgggat acggttttgt tttgctgccg cagcttccga agcagtggag
    58801 agattctttg tctgggctga aagggaaagg agaaggagag tacgaggagc tgtggaggat
    58861 ttttcacagc gccgtttcga ttcgggagag agagaaccgg gcctgccaga acagccatct
    58921 tcccctgcgg tttcgttcct atatgacaga attttaagaa acttacggat ttcttacatt
    58981 ttactgctgc agttgacagg ctgaagaccg tatgatatgc ttcaactgta ttaatacaaa
    59041 tagtacagtt aacgtgcaaa agcaggcggc gacagaaagg aggccgtatg attctgattg
    59101 attacagaga ccgccgtccc atctatgaac aggtggtgga aaagatggca gacctgatga
    59161 tacgaggcat ccttcctcag gacagccagc ttccctctgt gagaagcctg gctacggatc
    59221 tggcgattaa tcccaatacg attcagagag cttatgtgga attagagcgt cagggctata
    59281 tctattctgt gaagggaaag ggaagctacg tggcggaaaa tcaccaaatc agagaaaaaa
    59341 atcggcagga agtattaaaa agcctggagg ctttggtgga gaaagcggag gcagcaggcg
    59401 tcacgatgct ggaatttcag gaagcggtga ttcagatgta cgggaaaaag aaaaagccgg
    59461 aggaaggaga aggaggggag cggtatgatt gaggcggtaa atctgacgaa atactacgga
    59521 aaaattgcag cagtggatca tgtgaatgca gaaataaaag agggaaccgt atttggactg
    59581 ataggaacga acggagctgg aaaaagcact tttctcagaa tggcggcagg gattttaaag
    59641 ccggatgagg ggagcatcag cctggacggg gagccagtct ttgaaaatcc gaaggcaaaa
    59701 gccagatttt tctatatttc agacgaacag cattttctgg gaaattcatc tcctgaggag
    59761 atggcagtat tttacagatc tgtttaccct gcttttgaca ggaagcgctt ttttgagctt
    59821 ttaggcagct tcgggctgga tcgaaaaaga aagatttctg ccttctctaa agggatgaaa
    59881 aagcagcttt ctgttctttt gggcatctgc gcaggaacag aatatctttt ttgcgatgaa
    59941 acctttgatg gcctggatcc ggtcatgcgc caggcggtga agcggctctt tgcaaatgac
    60001 atggagacaa ggaaactgac gccggtcatt gcctcccaca atttaagaga gctggaggat
    60061 atttgtgatc atgtgggaat cctccacaaa ggcggaattc tcctgtccaa agatctggac
    60121 gatatgaaga tgaatattca caagatccag tgcgttttat acccagggac agaacctgag
    60181 cagatacgcg ggctggagat tatcagaact gagaaaagag gaagccttct caccctgacc
    60241 gtgagaggaa ggaaagagga gatagagaga cagatgcagc tgcaccatcc agtgtttttc
    60301 gaaatgcttc cccttacttt agaggaaatt tttatcagcg aaacggaggt ggcaggttat
    60361 gacatcaaaa aacttatttt ttaagctttt gagagagcag acaaaacaga ggatttggct
    60421 gattgccctg atgtgcctgg tttccttttt cgcttttccg gtggcagcgg ctttgatgtc
    60481 aggcgctttt ctggacatgg agcagctgac agcgcaggcc gaccgctcag ccgggctttt
    60541 gacggtagag atgtgcagaa atatggcgag ccaggagctg attgaagagt ttcaggactg
    60601 gatatccccg acaggccccc tgcttttgtg gatgattccg atagcggcag ctgtagcagg
    60661 cctggcggaa ttttcgtttc tccactccag aaggaagaca gatttttatc acagccttcc
    60721 agttaagcgg gagattttat ttgcagtttc ctatgtagga gggattctgt atgtggcggt
    60781 accttatgtg ataggacttc tggcagccgg actgatgatt cagataaagg ttatgccata
    60841 ttctgtggat tggggaacct tgcttacagg agctttgcag gggattgcct tttttattct
    60901 ttcttacagc gccgcatcgg cggctgctat tttgacagga aatatagtcg tcagtatttt
    60961 gggaatattt gtatttttct tctggggccc gctgacagtt tttctggttc acgcgtactg
    61021 ccaggcttat ttcacttcct tctatcaggc agaaggaatt ttgaactggc tgtctgtctc
    61081 caatacctct cctgtgttct tttactggac ggcaggagcg aatgcaggag gcagagcgct
    61141 gggggccctg gcagcaggag cggttatcgg tgcggcggca atgatattat acaggaagag
    61201 gccgtcggag gcggcgggaa gagcgatggc gtttcctctc agtcagcccc tgtttaaaat
    61261 aattctcacc attcctggcg ctctgggatt cagtttattc ttctatgaaa tgagaggaag
    61321 ctttgcctgg ggactttttg gactgttctg cggcgttctc attatggcat gcgtcataga
    61381 aattatttat cattttgatg tgagacaggc ttttgcaggg tggaagagca cagcggtggg
    61441 agcagcggct gccctgagca tattttgtct gtttttcttt gacctggctg gatatgacag
    61501 ttaccttcct gaacaggaga aaatcgaatc agttggagtg agcagttatc tgctgtatgg
    61561 aaatctgaca caggaccgca cagagatttc ggcagaaaag ggacatgacg gccagatttt
    61621 cgtaatcgga aatactccag gagagtatga ggtcttgaaa gaaatggaaa tctcagacga
    61681 agaagctgtc caggcagttc ttgagattgc agagaagggg atttcgagaa agaacagaat
    61741 cggcggccag gaagaaactg aagcttttac ctcgatacag aatggtgacg gtgagatgac
    61801 ggaggaaaac gtaccggaag aatctggaca ggtgctgatt cagtatcatt tgaaaaatgg
    61861 atcgaccgct acgagagtct actggattga tctgctggat gtaaaagagg cgtcagacag
    61921 gctttatgcc agcgcagatt ttaagaagga gagctatccc gttttttcca tggatgaaaa
    61981 ggaactggca ggagctaatt ttcatgtctt tgatacctac agccatatag aaacgggcag
    62041 ggaagagctt gcagagctgt tccgcgttta tcaggaagaa tttcttcagc tgactgccga
    62101 cgagaggcgg gaggaggctc ctctgggata cattcagttt aaaacagaga gtatgcagaa
    62161 taccattgat cagataagag cagagaaggg agattatacc agatttaacg actttgctta
    62221 ttatccggta tatccaagct ttgaacgcac agtgtcgctt ttaagagagg cggacgtgaa
    62281 aatggcggac agtctgaaga cggcttccat cgacagagcg gtggtagaga tgtggataga
    62341 ctcagaaagc agagatagtt ttaaaccgta ttcgaacgat ggaattcgga cgtacctttc
    62401 agacagcagc atgtgtctgg aggtaacaga accgtctatg gtagacgaaa ttttagacaa
    62461 tgtgggaacc agcgaggatc cactgtaccg caattgtctg gatgaatcta tggaagttgt
    62521 catttacgtg caggatggaa aagacggaga ggtggattct ttccggctgc aatttgagaa
    62581 agggcagatt ccaggatttg tcgaggagca gatgggagca tatattttta gttaagattg
    62641 actttccctt ctttacaggg tagaataaac aagactataa ttggcctgta aaggagggca
    62701 tgtaatggca ttttttgatg aactggggaa ggcgatcagt ggaaaaagca gggaagctgc
    62761 tactaaggta agagatctga cagagattct tcagctgaaa agcaagctgt ccagtgaaaa
    62821 ggaaaaggta aataaggcat atataaatct gggaaaggca tactacgacc ggcatgaagt
    62881 ttcagctgag gaagagtatg cagatgactt tgaagcgatc cgggccggtc tgctgaagat
    62941 ttcagagctg gaggaagaaa ttatttctct ggagggaacg aggatctgcg cagaatgtgg
    63001 agccaaagta gaaaaaggcg ctgcgttctg cggacgctgc ggcgcgcaga tgccattaaa
    63061 gcaggaagag acagaggaga cgttcgacag cagtgacgca gatgcggctt atacagaaga
    63121 acagccgcag caggagagca gtattccagt tcccgcagca gaaaagaaga cagaagagat
    63181 cagtgtaaca gctggcagga cagaggagta ggcagcatat ggacgcactt gtacaatggt
    63241 ttaccgagac cttatccggc gttatgtcat cggaaatagt aatttttatt atttccatga
    63301 ttccgatact ggagctgaga ggcggcctgc tggcagcttc tcccgctctt ttgaacgtgc
    63361 cgattactac tgcgattccg ctctgtatta tcggaaatat tcttcctatc ccattcattc
    63421 tgcttctgat taacagagtt ctggagtgga tgaagacagt aggagtcttt cgcccgacgg
    63481 ctctttggct ggaaaataaa gccatgagca aaaaggataa aattgaaaat tatgaattct
    63541 ggggcttagt cctgtttgtg ggaattccgc ttcctggaac aggagcctgg acaggagctt
    63601 tgattgcagc gctgctccgc attcgtttta agaaagcttt tttagctatc tttctgggaa
    63661 ttattctggc cacagtgatt atgagtattg tatcctatgg acttttaggc gcgttattcg
    63721 gttagcgtga tatttctcag cagacacagg acagaagggg aaagataagg cagagaggag
    63781 aaggtacaga tggaagagtg ctgcaagagt gcagagagac acaaacacag gaatttaaca
    63841 gagcagaagg atctgatgac caggctgaac cggattgagg ggcaggtccg cggactgaaa
    63901 gctatgctgg aggatgagcg ttactgcgtc gatatcctga ctcaggtatc ggctgttcag
    63961 gcagctttaa acggtttcag ccgcgttctt ttgtcaaatc acataaaaac ctgtgttgta
    64021 gatcagattg aagcgggaaa tgcagaagag acagtggaag aactttgcaa aaccattcag
    64081 aaaatgatga aataacagaa aagggcgaag ccgctgctgg ctttgccctt ttgcttaccc
    64141 ccaatatcat attttataaa aatcttatga tacagattat tcttcaggaa ttgtgcatat
    64201 ccgatttttc cataaggagc agcccaatcg attcggcagt ccagggcata aggtttgtga
    64261 tcatgtggat gataccattt ttaatggata ccatgtgttc cgggctatct cctggacctt
    64321 cttccattgt gtatccagat tggtcgcctc cccaggagtc tgaattaaac aggttcagca
    64381 ggaaagattg aagaaaaaac gaaaggaaca gacggtagat ttgtggtata ctctttccgt
    64441 taccgcctcc tagactggta cggaagggag gtgttcatgt ggaagcaatc acatctcttg
    64501 ttatcgcagt tgtggcaggc gtgattagct atctcgtctg taaatagttg gacggtgata
    64561 agtagccggt aacgagccta tggtctaagc tgccatacta aaatggaata gaaaaccccg
    64621 gagagtgcaa ctccggggtt ttcttctgtt agtcattcat gtggaaagac tcacatctct
    64681 ttagcctact ggcattatag tatatgcgta tttggattac aagatacgaa tatgctgttt
    64741 tttaccgaaa aatcaggaag gaggcgaaaa aggtgacaca gtcagaggta gaaaccgctc
    64801 tgaaacggtc tctcacaatg agattgtagc attaaagcgc tgcatggctt tgactacttt
    64861 ttgct
//
LOCUS       DBMDUW010000009        62127 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_512_length_62127_cov_5.170977, whole genome shotgun sequence.
ACCESSION   DBMDUW010000009 DBMDUW010000000
VERSION     DBMDUW010000009.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 62127)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 62127)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62127
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_512_length_62127_cov_5.170977"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..315
                     /locus_tag="ACZPCR_03255"
     CDS             <1..315
                     /locus_tag="ACZPCR_03255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008705918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229935.1"
                     /translation="FLLKSRAEVVAMSIFEYDEERERELIKKAEFESGKEEGLKLGKA
                     QGIELGKAQGIELGKIQGIAALIQAFQDLGASREAALLSLKKQFSLSEEEAERQLNQF
                     WK"
     gene            complement(391..1521)
                     /locus_tag="ACZPCR_03260"
     CDS             complement(391..1521)
                     /locus_tag="ACZPCR_03260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008396934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcxB family protein"
                     /protein_id="HIR1229936.1"
                     /translation="MSKGYFHVFHDPEDGFISGKAKDVARDMVVRGAFKPYGWLEILI
                     WTGISMFLSVKLCDHFQVESGIVRIIIWPFLGILFYLASRGIFFLSAWITSKKNAGNP
                     QFRHSFRQYLWFGDGSMFTESDDSRLDVSYRRIESLECENSRFILNMEAGKRIVLEKK
                     NFLEGNPNDFESFLRGKMAEEASLELKEDAPRAEVLESEDGIYRLYKAAEWNRIQSGR
                     EKYPVSMYLMVFLCVSAAFTFINMTLKEITLPFGIYLTVEAVFAAVCAAHYFLKNKQA
                     RSEKALRKAAAKEWNQIKGKADGMRKDLVFFKNGFKVQTEEYITSYDYRNVNTVIASK
                     DTLVVSGEGFFFVALMGTETDGYYEMKKLIESGSSLKVQVME"
     gene            1891..3594
                     /locus_tag="ACZPCR_03265"
     CDS             1891..3594
                     /locus_tag="ACZPCR_03265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003505747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-ATPase domain-containing protein"
                     /protein_id="HIR1229937.1"
                     /translation="MKASEELRTLLLSIDHKSYPAYKSLAGIYRFPGFQLSIDHVQGD
                     PFASPSHLSVFVPHKTAGFDASLYGTDARKTALEDYLIRQFGKEAAHFNFQAKGSGKS
                     GLISVTRCGQEILSRTACEISGDGVWLRFHAGFPANGRTINARELEKILFDFIPACVR
                     KSLLCASLPADEIQKRADLADDQEFIRSELERLNLAAFVADGSVLPRQSGVSDLPLKG
                     CVSFQSPDSLRIELTLPHKGVLTGMGIPKGITLIAGGGYHGKSTLLKALEMGVYSHIA
                     GDGREYVITDSTAVKLRAEDGRCIEDTDISLFINDLPNGKDTCHFTTEDASGSTSQAA
                     GIVEGMFSGCRAFLIDEDTCAANFMVRDELMQQVIHRKKEPITPFIERARQLFETCGI
                     STILVAGSSGAFFHIADTVIQMDSYRPVDITGKVKETLNAFPSPLKSQEEAPAFRLPE
                     LSRPYRVNGKRVSDAKIKCFDRDSFSIDKNTVNLHYVEQIADSEQTAALAYVLRYACS
                     VLADGEKSIAQIADVLEEMWESEGFSSFLKKSKGGGYAASGFARPRRQEVCACLARYR
                     K"
     gene            complement(3623..4906)
                     /locus_tag="ACZPCR_03270"
     CDS             complement(3623..4906)
                     /locus_tag="ACZPCR_03270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HIR1229938.1"
                     /translation="MFHKRILTRRDKFLLLSLIPVYFIVCGFILQPFSEIWPGIATLI
                     KEPDFLITDYFVVGGVGAAFLNAGVLTLLSIALIYFLDMEMDGHTITSACLMFGFSLF
                     GKNLFNIWAIMLGIWLYAKYHKTHMSHYVYVGLYGTSLSPIITQLMHIGDLPVAARFF
                     LALTAGITIGFLLPPLAAQVHHAHQGYSLYNVGFAGGIIATVIVSLLKSFGITVESRL
                     IWYTGSDFLFFTILSILFLGMAAGAFYFGGRGVVEEYSKILHSSGHGGSDYLRDNGGP
                     ATVLNMAVNGFMATLLVLIAGGDLNGPTIGGIFTIVGFSSTGKHIRNIFPIMAGVYLA
                     GLTKRWNISDPSPMLAFLFSTTLAPISGEFGWLSGLVAGFLHSSVALNVGIVYGGMNL
                     YNNGFAGGMVAIFMVPVIQSVRDRRARAKEEEALE"
     gene            complement(5002..6570)
                     /locus_tag="ACZPCR_03275"
     CDS             complement(5002..6570)
                     /locus_tag="ACZPCR_03275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008396937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase domain-containing protein"
                     /protein_id="HIR1229939.1"
                     /translation="MAFQFLSFIRENRAGALLSGAAALCTYGAWMTRQDITVDTEIMM
                     ADPDAMMNSWLGINRFGLVFTKHLFGQAAFHPVISRVLTVILLWITAMVLSFFVHKWS
                     GGQKRFRLFSAVFPVVYVTAPCFAEQLYFVLQSAEVVFAMLLCVLAAYGAGQFAFFGG
                     KWFWAAGSILLLVWAFGTYQAMAAVAASLIVILFMTVYLGENGKEQDRQRFGWLLAGV
                     KLAAVFVIGFVLYMAAAAAVRTLSGGSEAYVADMMHWKKDGFNVCVHWIAGELRRVFD
                     CYYVMFRPEFGWAVLLFFISSLVWMRCRKRPGKLWYLAAVCVFLLSPFLMTLVAGYYQ
                     PIRAHLVYPLVFASALSFLTAFLWPEEGKGAVRWRKGAASAAAALCLLISWSQAKDTA
                     ALFETIHQVSEQDISLTREIYEKAGETAEEEGRDIEDCTFIFLGKREAELPSEALRGD
                     VIGCSFYQWDAESPMGISRRIYDLMQTLQLPSEEPVLSRYLDSLPFAGEMTSYPEKGS
                     IRMDEDTVIVKLSE"
     gene            complement(6570..7529)
                     /locus_tag="ACZPCR_03280"
     CDS             complement(6570..7529)
                     /locus_tag="ACZPCR_03280"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016439391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1229940.1"
                     /translation="MKQISIIVPCFNEQEALPLFLQEIDRVCKGLSEYEFEWIFVDDG
                     SRDGTLSLLKERAKEDSRIKYISFSRNFGKEAAIYAGLEAAEGDYTAVMDADLQDPPG
                     LLPEMIEALESGDYDSAATRRVDRKGEPPIRSFFARMFYRLIRKISDIDIVDGARDFR
                     LMNRKMKDAIVSMTEYNRFSKGIFGWVGFRTKWIPFENVERAAGETKWSFWKLLIYSI
                     EGIVAFTTLPLSIAAYLGLIFCLVAFFMVLVVIAKTLMFGDPVGGWPSLACIILFVGG
                     IQLLCAGIVGKYLAKIYLEVKHRPLYLVAEDNLKDDLREKGEE"
     gene            complement(7797..8720)
                     /locus_tag="ACZPCR_03285"
     CDS             complement(7797..8720)
                     /locus_tag="ACZPCR_03285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005332067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HIR1229941.1"
                     /translation="MNYEGQICRAPMERSAFMLPVMVGCSYNGCKFCNLFRHLKYRKL
                     PVEQIESELQRVKACGGSPKRIFLGDGNAFDLPMEELSAILRLVKSYFPQCGMINMDA
                     TVTGILKKTREDLRVLYGLGARHLYLGIETGLDDVLSFMNKDHTLEEAYEAIRRLQEA
                     GLTFDAHIMTGVAGKGRGEENALALARFLNQTHPAHVVNFSMFLHKEVPLYREAERGT
                     FTQADELECLKEELSLIERAGTEEYPISYDGFHDFIEFRVRGILPRDREKMKEKLQAE
                     IRKYEGQRPVYSLVYGECPNIIRCEGDERIY"
     gene            complement(8893..9144)
                     /locus_tag="ACZPCR_03290"
     CDS             complement(8893..9144)
                     /locus_tag="ACZPCR_03290"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229942.1"
                     /translation="MTQKINLSFMHVISGVLFLVMIFFQMTGMQAAFGLMAAAVIIFE
                     LGLLAMEKSGRFTEGRTTKAEQALYLAAAVMVIVCMIFQ"
     gene            complement(9309..11573)
                     /locus_tag="ACZPCR_03295"
     CDS             complement(9309..11573)
                     /locus_tag="ACZPCR_03295"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HIR1229943.1"
                     /translation="MKSLVIAEKPSVGRDIARVLNCKKSGDGCLEGEKYVVTWALGHL
                     VELAAPEAYDKKYKEWKMETLPMMPKPFKLEVIGKTAKQFNAVKRQLFRNDVKDIVIA
                     TDAGREGELVARFILMKAGCRKPIKRLWISSVTDKAIKDGFSRLRDGREYDCLRDAAM
                     CRAEADWLVGLNATRALTCKYNAQLSCGRVQTPTLAMIAGREEEIRNFRPKSYYGLTA
                     RTSSPSLSLTWQDQKSGGMRSFDRERMERLLKELRDQPVKIVQVKRTPKKTMAPLLYD
                     LTELQREANKRFGYSAKETLNIMQRLYENHKVLTYPRTDSRYLSSDVADTIKDRLAAC
                     GTGPYRKLAARLSKQTWTKKAAFINDAKVSDHHAIIPTEQFVQLQHMTVEERKIYDLV
                     VRRFLAVLLPAAEYDETVITAEIGGQRFTARGKVMRSQGWREAYETSAGTDSGADSSF
                     LSFDDLDDETDEEEERGGAARVKEQTLPDIKEGAVIAGAGLSLTEGKTKPPAPFNEAT
                     LLSAMENPVKYMESHDKAMAKTLGETGGLGTVATRADIIEKLFSSFMLEKRGKDIFLT
                     SKAKQLLKLVPEDLRKPELTAEWEMKLSKIAKGELKRDAFMGDICAYTEELIGEIKGG
                     EGTFRHDNLTNTKCPRCGKRMLSVKGKNSQMLVCQDRECGYRETVSRTSNARCPKCHK
                     KMELRGKGENQTFSCSCGYKEKLSNFKERRQKEGAGVTKRDVAKYLNKQNQEEKMVNN
                     PFAEAFKNLGLDKQ"
     gene            complement(11570..12094)
                     /locus_tag="ACZPCR_03300"
     CDS             complement(11570..12094)
                     /locus_tag="ACZPCR_03300"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013270830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HIR1229944.1"
                     /translation="MREQKKADNVTLIGMPAAGKSTVGVLLAKRLGYSFVDVDIVIQE
                     QEKRLLKEIIAQEGMDGFMAVENRVNAALQAEQSVIAPGGSVIYGAEAMAHLKEIGLV
                     VYLKISYEELTKRLGNIVDRGVVLKEGMTLKDLYEERAAYFERYADITIDEEGKDLGQ
                     VVDELRRILEERLS"
     gene            complement(12091..12789)
                     /locus_tag="ACZPCR_03305"
     CDS             complement(12091..12789)
                     /locus_tag="ACZPCR_03305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013280179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HIR1229945.1"
                     /translation="MSKQDWKPGNMLYPVPVIMVSCQKEGGKPNIITAAWCGTTCSSP
                     AMLYVSIRPDRYSHHIIKETGEFVANLVTEDLTFATDYCGVKSGRDTDKFKDMKLTPL
                     KSKKVRCPGIEESPVNLECRVTQIIPLGSHDMFLAEIVNVTVDEKYMDETGRFHLNEA
                     GLVSYSHGEYFKLGKKLGKFGYSVQKKKSGKKAGEKRGSQPEKQKAPLKNRANGGTAR
                     KDRGKAGSDRRDRK"
     gene            complement(12805..14457)
                     /locus_tag="ACZPCR_03310"
     CDS             complement(12805..14457)
                     /locus_tag="ACZPCR_03310"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015544087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HIR1229946.1"
                     /translation="MSDSKKRKTIVIGHKNPDTDSICSAICYANLKRILTGEKFTPAR
                     AGHVNSETQYVLDYFGVEAPKLIENVRTQVKDIEIRETAGVQKNISLKKAWNLMQDNT
                     VVTLPAVTEDNILEGLITVGDITRSYMNVYDSSILSKACTQYSNILETLEGALVVGDE
                     NAYFDQGKVLVAAANPDMMEYYIEKNDLVILGNRYESQLCAIEMEASCIIVCEGAGVS
                     MTIKKLAQERGCTVLTTPYDTYTAARLINQSMPISYFMTKDNLITFGTDDFIDDIRDV
                     MASKRHRDFPILDKDGKYKGMISRRNLLGARGKNLILVDHNERSQAVEGMDSANVLEI
                     IDHHRLGTVETMSPVFFRNQPLGCTGTIIYQMYNENKVEIDRKTAGLLCSAIISDTLL
                     FRSPTCTPMDQAAALNLAQIAGIDAEEFAKEMFEAGSKLKGKTDSEIFYQDFKRFTAG
                     KLTFGVGQITSLNAEELEKLRERLLKYIGEARQEQKVDMMFFMMTNILEQSTDLICDG
                     QGAEQLAAAAFHLREAANVVKLPGVVSRKKQLIPGLMIATEQ"
     gene            complement(14677..15621)
                     /locus_tag="ACZPCR_03315"
     CDS             complement(14677..15621)
                     /locus_tag="ACZPCR_03315"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HIR1229947.1"
                     /translation="MGKKCIGIDVGGTTVKLGLFEMDGTLMEKWEIPTRKEEDGAFIL
                     PDAAASVKEKLSERGLSLSDLAGAGLGLPGPVMPDGFVGVCVNLGWKNKNPQKELSAL
                     LDGALVRTGNDANVAALGEMWQGGGKGFSDIVMVTLGTGVGGGVILDKKIVAGKHGTG
                     GEIGHLRIREGEKEPCNCGGYGCLEQVASATGIAREARRAMEQDSSDTEMRKFGADIT
                     AKDVLDCAKAGDAMACRVMDTVFYYLGWALSVVSMTVDPEVFVIGGGVSRAGSFLTEG
                     IRKYFDQFTTLSDQKAEITLAQLGNDAGIYGAARLILD"
     gene            complement(15836..16840)
                     /locus_tag="ACZPCR_03320"
     CDS             complement(15836..16840)
                     /locus_tag="ACZPCR_03320"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF012407.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HIR1229948.1"
                     /translation="MKKTVTVFRGDGIGPELVDSVLKILEAAGAPLDYELFDVGENEW
                     KRSGSLIPEAACRSFERTKVLLKSPITTPVGTGFRSLNVTLRGMYDLYANIRPVRSNA
                     AVHTPFHDVDIVIFRENTEGLYVGQEEQIDENTVHAVKIVTRKASERIIRDAFEYAAL
                     HGRKKVTCVHKANILKKSDGMFLSIFREIAGEYPQIEADDKIIDNTCMQLVMNPNQFD
                     VMVMQNLYGDIISDLCSGLIGGLGLVPSSNIGTEYAMFEAVHGSAPDIAGKNLANPTA
                     FLWSACMMLEYIGETECAARIREAVDEVLQEGICLTKDLRGTASTSEYTEEIIKKLQK
                     "
     gene            complement(16911..18224)
                     /locus_tag="ACZPCR_03325"
     CDS             complement(16911..18224)
                     /locus_tag="ACZPCR_03325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007711498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HIR1229949.1"
                     /translation="MLSILLVASIALAVVLGYKTQINTGFFCMAFAYLLGCFGLGMTT
                     KELIACWPTSTMFVILSVSLFYNFAAVNGTLEKVSSHLLYTCRKFPGMLPFALFFVAV
                     VLSIMGAAYFTVLAFLAPITMLICEEAKMDKLTGAVAINCGALAGGNFSTAALGVVFR
                     GLMETAYEAEPALAAPDSFTEEMKIFAFSIVFSLILISVFRFGFRSNRGIGKGVVFEK
                     PAAFEKDQKLTLYLMLAMMAVVLVFPLLKLALPQNTLVGVISGRIDVGLVAVCFAVAA
                     LLLKLAPQKEVIARIPWNTILMIAGAGMLIAVAVKAGTIEALSAWIGSNVPTPMVPLA
                     FSFVGAFMSFFSSTTGVVAPALFPLIPPLAAATGLNPAALFACTVLGAQSSAISPFSS
                     GGSLILGSVGSEEDRNHLFNRLLFIAVPVSVICCAVYNLAVAELL"
     gene            complement(18227..19096)
                     /locus_tag="ACZPCR_03330"
     CDS             complement(18227..19096)
                     /locus_tag="ACZPCR_03330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007711499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6282 family protein"
                     /protein_id="HIR1229950.1"
                     /translation="MSSNLMKGVIDMHVHSNPDLRLRAYDDFELMEAGIRAGARGIVI
                     KTHQGSTAERAYLCNRYNERVHGGTNDFTMFGSITLNRVVGGINPKAAETALKLGAKV
                     VWLPTQSARNHMEKVGQDASQCAEVVRDGKIVPELSDIFQLVKDFDAVLGTAHISPKE
                     AFIVVEEARNAGIKKIVLTHPEWWIVDMSLEDQIRMVKDYDIILERCYAQNMGNGRYK
                     SNLQDNLDMVKEAGYKNVMVSTDGGQTENPHWELALAEYIQFLLDGGISRDEVYYMTH
                     TIQRQLLGIREEE"
     gene            19262..20200
                     /locus_tag="ACZPCR_03335"
     CDS             19262..20200
                     /locus_tag="ACZPCR_03335"
                     /inference="COORDINATES: protein motif:HMM:NF015431.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HIR1229951.1"
                     /translation="MDMKELNYIVAIADAGSISAAAEKLFMAQSSLSQALSLYESELG
                     TPIFVRTSRGVRPTPSGSVFISHARQILNHYRLAQSEVWDIEGLNGGRVEFGISSFRG
                     TYLLPPALKQFHASYPQIQVEITELDSWDLEDRILKGLLDIALIAAPSEKIRHSCDFL
                     MKDEIVLAASVNHPVMAFAHPCGQHSGEYWIDLKDTKDFTYILGSPGTVLGKMLRREL
                     LKAGVEPAAASSQVSAPMAAAMARAGLGLAATYRSCIPAHESAQYLKIGRKGVFLDLA
                     LIYPSGGYRSKAAAALGEVLRQTYLGLERETRQIYD"
     gene            complement(20342..22321)
                     /gene="tkt"
                     /locus_tag="ACZPCR_03340"
     CDS             complement(20342..22321)
                     /gene="tkt"
                     /locus_tag="ACZPCR_03340"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002588315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HIR1229952.1"
                     /translation="MNQIDTLSINAVRILAADAIQKANSGHPGLPLGCAPIGYELWAH
                     HLNYNPSNPDWANRDRFILSGGHGSMLLYSLLHLFKVGDLTKEDLMNFRQVGSKTPGH
                     PEYGHTVGVEATTGPLGAGMGMAVGMAMAEAHLASVFNKEEYPVVDHYTYVLGGDGCM
                     MEGISSEAFSLAGTLGLSKLIVLYDSNRISIEGSTDIAFRENVEERMRAFGFQTITVE
                     DGNNIDSIAMAIEAAKQDTERPSFITIKTEIGYGCPAKQGKASAHGEPLGVENVKALR
                     ETLNWPYEEAFFVPEEVYRHFDELSNEKAEAEAAWNVMFAAYCEEYPEMEKLWNQYHN
                     GTAEDLLNDDSYWAAQEKAEATRSLSGKIINVLKDRLPNLIGGSADLAPSNKTYMDGK
                     GDFSKEDRSGRNLHFGVRELAMAAIGNGMALHGGLKPYVATFFVFSDYVKPMARLSAL
                     MGTPLTYVFTHDSIGVGEDGPTHEPIEQLAALRAMPNFHVFRPCDATETQAAWYSAVT
                     SKSTPTALVLSRQNLEPMKGSSKEALKGGYVLEDCEGTPDVILIATGSEVGLAVKAKA
                     ELEKDGMKIRVVSMPCMDLFEEQSAEYRESVLPKAVRKRVAVEALGSFGWERYTGLDG
                     AIVSMKGFGASGPAAELFEKFGFTVENVVNTVKSL"
     gene            complement(22366..23640)
                     /locus_tag="ACZPCR_03345"
     CDS             complement(22366..23640)
                     /locus_tag="ACZPCR_03345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5711 family protein"
                     /protein_id="HIR1229953.1"
                     /translation="MSNMDSMDREQKKRQLRQRMISSPGGQSQGGGRGLDEEEIVRNA
                     EARTRKKRIRMFIILAALILAALAAAYYYLYVRRYESYRVVWEKQIPASENGFAGYEP
                     FGSNVLKYTKDGASYIDSRGKIVWSISYQMKSPVCYVNGSYAVIADRQGNSLYICNQE
                     GQRGQAETTLPILRASVSAHGVTAVLLEDSTASYISFFKEDGSELDWLIKTVMSKSGY
                     LMDVSLSPEGSQVMVSNVYLQDGMMGNRVAFYNFSEYGKSYPDRLVGGFEEMKDSVIP
                     RVRFLNEDRACAFGTGQIGFFSLENQTSPALSAHIKLEEEIKSVCYSDKYVGVVVENP
                     EGESDYRLDVYSAGGKLKFSQPVSFQYKEIDIDGDMVILYNENSCEIYNMSGKCRFSG
                     SFDFTFSAVRAGKMENELIFTGGDTVRSIRLK"
     gene            complement(23759..25228)
                     /locus_tag="ACZPCR_03350"
     CDS             complement(23759..25228)
                     /locus_tag="ACZPCR_03350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HIR1229954.1"
                     /translation="MGDLYEPLSKLPKNIRQIGDRDDTVRLYIEDYVSTYLKRLFPSG
                     GQDLRAGLLLGTERTENGVPFIFVDGALEMEDVTAEGEKVEFTEAAWKKAYQSMEESF
                     PRRTVQGWFLCGAPGCTLSPLNYWKQHGQYFSEKNQLMYLNSGLEGEESVYVTSDDGF
                     YRLKGYSIYYDKNQMMQDYMICRKDVRRVESGAGDRVIRDFRERMEDRKKEAVSQRHT
                     VRNLGLLCSTMSMVILAGGVAMMNNYQKMQEMETVLVSVLPEGARPWDPDREEREESA
                     PVIVEEIKGRIYPKTEEESNRLVGSSAGGEKGEEIVKMEPDPEKTAEIQEKQDLSQET
                     ALESSAPELPAEAQPESQNSGDGLREPESQGAEFQKSESQTESQTEDPSAESRETQAD
                     GNPKAQASEHQGSETASQETKEAAAPATDKKPGGTYAVGDGETLYGICFKLYGNVNHV
                     EDICALNGMTDMNHVAAGQKLILPADVPVAEEMKDLVEK"
     gene            complement(25367..25966)
                     /gene="yyaC"
                     /locus_tag="ACZPCR_03355"
     CDS             complement(25367..25966)
                     /gene="yyaC"
                     /locus_tag="ACZPCR_03355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HIR1229955.1"
                     /translation="MKMLEWMSAKDSRNIYYFNSDRNFKAEDFARQLHQMIEEEKARQ
                     GKKGVVFLCIGTDRSTGDSLGPLIGYKLRDMKRSCAAVFGTLERPVHAMNLEEYARII
                     KNCYHDCLVVAVDASVGNREHVGYLTLGKGALRPGLGVSKELGAVGDIFITGIVGGCS
                     SYDPLMLQSVRLSVVMRMADCISRSIRIVEKFWDNAALI"
     gene            complement(26106..27212)
                     /locus_tag="ACZPCR_03360"
     CDS             complement(26106..27212)
                     /locus_tag="ACZPCR_03360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006771816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229956.1"
                     /translation="MAQAITDFKGFLSDAKQIALELADLEREEQQAKEEEERLLKALE
                     SEKKAVADNINLTVKRRREEINKSYDSEIAGAQDRLKKTRVRREKAKNQGIKERIKEE
                     TSELHLHNRELRVRMKTLFQKEHVPSFCQSGFYYALYFTRGFKEAMLLLISLVVCFLA
                     VPCGIYSLLPVQKTLYLILIYFACVIVFGGLYTIVGNMTRGHHQQALREGRQIRNVIL
                     SNNRKIHIITSSVKRDRNESLYNLERFDDEISQLEQDMDDMLKKKKDALNSFENVTRM
                     IISDEITENSREKLERMAEEYEDAVGQLKYVRTILQEKRMYMTDTYESYLGREFLNVE
                     KIDGLKRLIESGEASNISEAIERYKNGEGPAVRK"
     gene            complement(27293..27559)
                     /locus_tag="ACZPCR_03365"
     CDS             complement(27293..27559)
                     /locus_tag="ACZPCR_03365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007871264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229957.1"
                     /translation="MFRLWAKLWKDNRMQRDTVIENGDYSMSRTAMVFDAMEKVCYEF
                     DLGQPIWLDANIEDFKWHDKTRFSKDSFVESIDFDYLEIQVIEE"
     gene            27824..29143
                     /locus_tag="ACZPCR_03370"
     CDS             27824..29143
                     /locus_tag="ACZPCR_03370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008410 - CoA-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0006637 - acyl-CoA metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HIR1229958.1"
                     /translation="MANDYRNRFVTPETAAKAVRSGDWVDYGFGAGFPELMDKALAKR
                     KDELKDVKIRGGLVIRPRIEVVESDPEQSAFTYYSWHIGDYERKLQSRGLCQFIPMIL
                     RSLPELYRRHIRVDVAFVPVSRPDENGFCGLGISNYAWRTIFEQARTVIFEINERLPR
                     LQGVDGSHRVHLSEADYIVEGEHEPLPVRTYRDPSATDIEIAKRVVEEIPDGAVLSLG
                     VGGVPFTVASMLAESDRKDLGCHTGTISDAFLALHKAGKLTNSRKEIDTGYSSWNLAM
                     GSEELYQWLDEEPELFRPADVDYIHSPERISRMKNVISINGGVELDLMGQENAESAGS
                     RQLSGTGGQLDFLEGAFRSEGGKGFICLASTHKKKDGSLKSNIVPFIPGGSTVSAPRT
                     MIQYVATEFGVARLSGLSLKERAEAMASIAHPDFREELLRYAAEHFA"
     gene            complement(29304..30653)
                     /locus_tag="ACZPCR_03375"
     CDS             complement(29304..30653)
                     /locus_tag="ACZPCR_03375"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HIR1229959.1"
                     /translation="MGREVAFDYSKAAPFVRAEELENMKSAVMCAKDVLVGKTGAGND
                     FLGWIDLPVDYDKEEFARIKKAAEKIQNDSDVLLVVGIGGSYLGARAAIEFLSHSFYN
                     VLPKGKRKTPEIYFVGNSISSKYIQDLKDVLEGKDFSVNIISKSGTTTEPAIAFRVFK
                     KMLIEKYGKEEANKRIYATTDRAKGALKNLANEEGYESFVVPDDVGGRFSVLTAVGLL
                     PIAVSGADIDKLMEGAANGRRKALELPYEENGALLYAAVRNILLRKGKQVEIAANYEP
                     SLHYVSEWWKQLYGESEGKDQRGIFPAAVDLTTDLHSMGQFIQDGARIMFETVLNVES
                     SPAEVLLEEEDVDTDGMNYLAGKSVDFVNKSAMNGTILAHTDGNVPNLMVNIPEQNEF
                     CLGELFYFFEFACGISGYLLGVNPFNQPGVESYKRNMFALLGKPGYEEAREELLKRL"
     gene            complement(30769..31794)
                     /locus_tag="ACZPCR_03380"
     CDS             complement(30769..31794)
                     /locus_tag="ACZPCR_03380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229960.1"
                     /translation="MLEMLQTGKALYALAAIGAIGAISKLITRSLYKRLIRETDNMAM
                     TKNRNLKALKQKLENACRLNQNIVNTEAYLERQMYGFRFMKISLNSWNNLSAQMTILG
                     IMAGGAASFAAYWYRLDSYYIVLYASAGAFLGLALAFLDSSFSIGLKQQRLANALLEY
                     TDNSVLVRAFRDNAGQQERFQDSARRLPVREADTDELSEREAIIRENAIRDGLIKEAV
                     KMPERQREAEDKASLFRAKKADKPAGLKRLKAEKTGRVKKTAALVEEKNALFQNLKEE
                     SQNVPSAQEPSGEGIRDIDYLKHSLEQIAASRERSKQQEEWTKNLKPEEMKALGELLR
                     QYLSAES"
     gene            complement(32033..32728)
                     /locus_tag="ACZPCR_03385"
     CDS             complement(32033..32728)
                     /locus_tag="ACZPCR_03385"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002589258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HIR1229961.1"
                     /translation="MLGIIGAMDEEVAKIKEEMTQVQVTRTAGMDFYVGKLCGQDAVV
                     VRSGIGKVNAGMCTQILADRFQADAVINTGIAGSLKNEINIGDIVISTDTVQHDVDAS
                     GFGYPKGQIPRVDTFAFKADEKLCALALSCNEKVNSDIQAFQGRVVSGDQFISDKEKK
                     KWLAEEFGASCTEMEGGAIAQAAYLNGIPYLVIRAISDKADDSAGMDYAEFEAQAIRH
                     SVNLILEMAKQMN"
     gene            32892..33137
                     /locus_tag="ACZPCR_03390"
     CDS             32892..33137
                     /locus_tag="ACZPCR_03390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002605485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HIR1229962.1"
                     /translation="MLFKTCGVCSSAIEFDVKDNKITNVHFIGGCSGNTQGVARLIEG
                     MDVDEAISRIDGIHCGARPTSCPDQLARALKQYKASL"
     gene            33343..34410
                     /locus_tag="ACZPCR_03395"
     CDS             33343..34410
                     /locus_tag="ACZPCR_03395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002605677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HIR1229963.1"
                     /translation="MKKIILTGGGTAGHVTPNLALLPSLRKEEFEIHYIGSYNGIERR
                     LIEDAGIPYDGISSGKLRRYFDIKNFSDPLRVLKGYGQAKRLMKQYHPDIVFSKGGFV
                     SVPVVLAAKHYKIPVIIHESDMTPGLANKICIPAAKKVCCNFPETLNYLPKDKAVLSG
                     SPIREELLTGDRLSGLQYAGLSANRPVILVIGGSLGSVTVNHAVRSILPKLLSQFQVI
                     HICGKGNLDESLIGTSGYVQYEYVDKPLRHLFAAADLIISRAGANSICEILALRKPNI
                     LIPLSAAASRGDQILNANSFAKQGFSTVLEEEVLTSDTLYQAVSDTYKKRTAFIEAME
                     KSTLNNAVETIMNLIRECAKS"
     gene            complement(34498..34920)
                     /locus_tag="ACZPCR_03400"
     CDS             complement(34498..34920)
                     /locus_tag="ACZPCR_03400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008396983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HIR1229964.1"
                     /translation="MKDKDCIFCKIANGEIPASTVYEDENFRVILDLGPASKGHALIL
                     PKAHYQDLCHLDEETAAKVLPLAGKIGSAMKKTLGCAGFNVVQNNGEAAGQTVFHFHV
                     HIIPRYENGPAMVTWEPGKAEPEDLAKISSMLKAELES"
     gene            complement(34966..35433)
                     /locus_tag="ACZPCR_03405"
     CDS             complement(34966..35433)
                     /locus_tag="ACZPCR_03405"
                     /EC_number="3.4.21.-"
                     /EC_number="3.4.21.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007706924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HIR1229965.1"
                     /translation="MTEGGEYYRLFTSIFLHFNIRHLLNNMLVLFVLGEKLENCLGHV
                     KYLLFYILCGIGANLISLQFYLKSGEPFTMSAGASGAIFGVIGGLIWIVYRNRGRIGD
                     MNSRQLVLMAILSLYLGFTSTGVNNAAHVGGLAIGIILGIPFHAWVSARRTGR"
     gene            complement(35835..37298)
                     /locus_tag="ACZPCR_03410"
     CDS             complement(35835..37298)
                     /locus_tag="ACZPCR_03410"
                     /inference="COORDINATES: protein motif:HMM:NF039422.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6382 domain-containing protein"
                     /protein_id="HIR1229966.1"
                     /translation="MEKIKAGYRREMNHNYMIIEAFSDDTECYESRMLSGNTIEGLLK
                     FRQKITETGIEFYYEITSKQPLSRLLEGRLISYEEIKEILLAAARVLSRIEEFLLKEE
                     QILLEPEFIYVEPEPFSIFFCILPGYSRSFPEAFTGLLQYILEKVDHQDHRSVVLAYG
                     LYHESLKENYGMEDLLRYLSGIESGKTEWKEKKKTQNEDRWQREQKTAFLEGESDDRW
                     EESEDEEDDILNGREFEEAAAEEISGKKESILQRKKQSSGALKIVCLLLAAEAAVYFW
                     LGEEGIRIYGVLPVFAIAGGYLIWTAVQKFISSKCEEDHETAVNTEHLCKAEIKSRKE
                     SEPKGIVRQEKAEKKEQEELNILFQALEDDTSPEEPVWEDKNTQLLTGVSEKEKRCAA
                     LESLSKDRGDIEIPYVPFLIGKHREMNDFILDYPTVSRLHLRIDQKEDVYIFTDMNST
                     NGTTVNGYKLEANETVSVKEGDSIQIAGLNYRFREFL"
     gene            complement(37352..37786)
                     /locus_tag="ACZPCR_03415"
     CDS             complement(37352..37786)
                     /locus_tag="ACZPCR_03415"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229967.1"
                     /translation="MKEIRETGGEQVQKQLSPRRKMADAVITVEASFVMAVVLFVCGA
                     LISQGFYVHERNTGMLILMDALEQAQTGGENTDTLEMSERWGNQALSAYYRCGGCKIE
                     IVKRGTVLTGSFKHRNGKTGGNVQMKLFEPERFLRMVRAGGI"
     gene            complement(37836..38309)
                     /locus_tag="ACZPCR_03420"
     CDS             complement(37836..38309)
                     /locus_tag="ACZPCR_03420"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229968.1"
                     /translation="MKLVFAAFLCVCAWEDFREKKISVLFLWAAASVAAAWTAGYYII
                     LLDWADMYEAHLWLAMRGAALIPGILLLVLSKITKGAVGQGDGFFFLVSGMYLGFWDN
                     VALLFFGLLICSLWGMGMLIWGMFEKKKIKNIQLPFLPFLVPAAVALAAFQMGAV"
     gene            complement(38306..39145)
                     /locus_tag="ACZPCR_03425"
     CDS             complement(38306..39145)
                     /locus_tag="ACZPCR_03425"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_process: GO:0009297 - pilus assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TadE/TadG family type IV pilus assembly protein"
                     /protein_id="HIR1229969.1"
                     /translation="MKNWKRKRQNAALTIEAALGLTLFIFFSICMMTPMEMLRTRQKV
                     QTALETAARDLSQYGYILYRLDQGDEGVLEQKEDWIDQLPDFLAGLSVKAYLREKIAD
                     LVGEEKLEKLVISQAELMEDGENIKLTAEYSLKLPFSILRIQGIPAVSQTVRRAWIGS
                     RGDRGGEVESEEGVEEMVYIGSSMGRYHRLRICHYLTNDFKAVPYDTVEDLRSHSGGK
                     YYACSVCGSGENGGTVYIMPNGSSYHTRMDCSSVVSYVREVPLREVKHLGACSYCGGG
                     GKE"
     gene            complement(39296..41149)
                     /locus_tag="ACZPCR_03430"
     CDS             complement(39296..41149)
                     /locus_tag="ACZPCR_03430"
                     /inference="COORDINATES: protein motif:HMM:NF039199.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5702 domain-containing protein"
                     /protein_id="HIR1229970.1"
                     /translation="MILICIVSLMCTLLQSARMAGSGWYLQTALNSSLDSLMSKYHRE
                     AWETYHIFLLEADRKEELEREISEYLDQYLASDTVYGMKKKKLAVSDMVMVTDERGEP
                     LEREILDYMRYGIWTEAGKEMDLDGLAETIRSADGIAAVKTAYQISSDHVFRLEEALE
                     DIRESLEKQKKYKEEGQRELENCQGRAFIKTGKKLAGEMERMPALSEKYDKAAALLEA
                     ELDASEQEAEQQKEKIGEQAWTLIKSQMDSYRSYTDKEGERRGEVERIKAQTAENRGI
                     VEAAVEMAEETQEYIDSWESDDDDDELDEEELWDDVRSVLNRCQIPSPSYQKGIADKK
                     RLRILERISKMASKDLLDLTLPEGAKPSLRTMDMPDFPSGGGEGYEIGLRLTGAGELA
                     DRALISEYAAAHFLRFQAGQKEENKEKGGLFYEQEYLLNGKKRDRDNLHQMVKKLVGV
                     REGLNLIHILGDSEKQNEARLLAASLTGAASVTPLADIVAFFIMGVWAFAESVEDVRA
                     LLKGEQVPLVKRDSDWKLDLDELFRFVDNQEEIHDSGGQTGLDYGQYLKGFFLIQDQA
                     QRNERMLDMMQYNLFRNQGSFRMKRCSVGMAAECTASGSAFDIRKKAQYRY"
     gene            complement(41208..41390)
                     /locus_tag="ACZPCR_03435"
     CDS             complement(41208..41390)
                     /locus_tag="ACZPCR_03435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp1 family type IVb pilin"
                     /protein_id="HIR1229971.1"
                     /translation="MGYNAEIREFFEDESGVGVIEVVLILVVLIGLVIIFKNQINKLL
                     ETIFKQINSQSKEVYS"
     gene            complement(41410..42636)
                     /locus_tag="ACZPCR_03440"
     CDS             complement(41410..42636)
                     /locus_tag="ACZPCR_03440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006772756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin-like domain-containing protein"
                     /protein_id="HIR1229972.1"
                     /translation="MKFEKKRKIQILCIAAGAFFFLIYPMAGASDFLKPGGVIERNTY
                     GQGDKEGILIVEGLPDGKEEIEIQIKERQYSKKEADNKFGQAFQKAQQEALADNPSFD
                     KVSSSLKLSSRLDSFGMTMKWESQNPELIDPGGEVYLEQMQKEQEKTVLFLTLKAGNY
                     QRKYEIPVTVIKPVLTKQEKSLKLLADTIESADEEQKYEEKLILPAKLEGREIRYSEK
                     HSCDRYIFLLLGAAAAVLMEYRESSQEREEKKKRNTELALDYSDIVSGLCVYLGAGFP
                     VRKAWEQLAKEYEMSLKLPGGRKRAGYEEIRISVGRMNQGMSELRAYGEFGKSCGLRS
                     YRKLAGLMTQYVKNGSGSLRKNLEEEMENAFEERKAAARKIGEETGTKLLIPLFMMLL
                     IVMVMVSVPAFLAFGI"
     gene            complement(42626..43471)
                     /locus_tag="ACZPCR_03445"
     CDS             complement(42626..43471)
                     /locus_tag="ACZPCR_03445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HIR1229973.1"
                     /translation="MWKAFWSRWEIFRTGKSWRCLGRPGHSASGREEGGGTEYETYCL
                     SAREWIRYSCQGAAVCALFAYVFYRNFFSFFLFLPLGLLYPLYKRIDLKQRRQEELKR
                     QFKESVLMLSSSLAAGYSMENSFAQAQAQLEEMYGERGMMSKEFAVMRSQLSMNRTLE
                     ELWGDFAKRSGIEEIRSFAQIFKAARRSGGQLGMIISHVSEIIGGKIQVQEEIRLMTA
                     QKQFEQKIMNLLPLLIVLYIDLTSPGFFDTMYQTAAGRIVMTVCMLVYAGAYILAGRM
                     LDIEI"
     gene            complement(43392..44543)
                     /locus_tag="ACZPCR_03450"
     CDS             complement(43392..44543)
                     /locus_tag="ACZPCR_03450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006778188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpaF family protein"
                     /protein_id="HIR1229974.1"
                     /translation="MEDEELSELIDAMIQQAGETLYLPLAERVKLREELYNSFKKLDI
                     LQELVDNPQITEIMVNGEQSVFVEKGGAICRWNRSFETREQLEDLIQQIVSRVNRTVN
                     AASPIADARLEDGSRVHVVLPPVALDGPVLTIRKFPEPITMERLISLGSVTETAAGFL
                     KKLVKSGYNLFISGGTGSGKTTFLNALSEFIPEEERLITIEDSAELQITHVPNLVRLE
                     TRAANHEGSREITIRDLIRASLRMRPDRILVGEVRGAEALEMLQSMNTGHSGSISTGH
                     ANSSRDMLLRLETMVLMGADLPLAAIRSQIASAIDIFIHLGRLRDRSRKVLEIEEVTG
                     IEDGEIALHPLFQFKETKGGKKGGVEGILEQVGDLQNRQKLEMSGETWP"
     gene            complement(44718..45728)
                     /locus_tag="ACZPCR_03455"
     CDS             complement(44718..45728)
                     /locus_tag="ACZPCR_03455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-loop NTPase family protein"
                     /protein_id="HIR1229975.1"
                     /translation="MKRIMAVYDLDLFYARRFADVMNQKENIPFAVMAFTSLERLRQY
                     AGGHSIEILLVSSQVNRDEICDLGIGQVITLTEGEKKEGDKDYPSVYKYQSSSDIIRE
                     VMACYSAGDEPDGAEHGRAASVIGVYSPVGRCLKTSFALTLGQLMAADRRVLYVTLED
                     YSGLASMTGEEYKSDFSDILYYFSQRNLNCMRLSGIVHSIGNMDYIPPARYPEDLAHI
                     PAEQMAELIRKLAADCGYEIIILDVGNYGHQAAPILSVCQIVYMPIKEDGISSAKIRE
                     FEAYAERTGNSGMLDKVKKLKLPYHRGFGRRENYIEQLLWSELGDYVRKLMRGSREEM
                     EC"
     gene            complement(45725..46240)
                     /locus_tag="ACZPCR_03460"
     CDS             complement(45725..46240)
                     /locus_tag="ACZPCR_03460"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: protein motif:HMM:NF013632.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HIR1229976.1"
                     /translation="MGLKWILHACLTAAAVSDWKTGKIPNMLVKTAVLAGFGYFLAAG
                     RGAQAGPAAARGMMILLCLFPLHLFRMIGAGDIKMMACMAVFLDREEWIQVMAGALVM
                     AGCWSACAMWRRGMVRERFQYLLFYVQRFIRTGERTAYRTEEMDSSALLCLGPFLWAG
                     MTLFMIREGAG"
     gene            complement(46615..47271)
                     /gene="fsa"
                     /locus_tag="ACZPCR_03465"
     CDS             complement(46615..47271)
                     /gene="fsa"
                     /locus_tag="ACZPCR_03465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005422638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HIR1229977.1"
                     /translation="MKFFIDTANVDEIRKANDMGIICGVTTNPSLIAKEGRDFKQVIQ
                     EITSIVDGPISGEVNALTTDAEGMIKEGREIAAIHPNMVVKIPMTAEGLKATKVLSEE
                     GIKVNVTLIFSANQALLAARAGAAYVSPFVGRLDDISQPGVELIETIMDIFETHGIET
                     EVIAASIRTTMHVTECAQAGADIATVPYKILEQMLRHPLTDQGIEKFQADYKAVFGEK
                     "
     gene            47495..47866
                     /locus_tag="ACZPCR_03470"
     CDS             47495..47866
                     /locus_tag="ACZPCR_03470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002605692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HIR1229978.1"
                     /translation="MTEAEELKQCFHQCMPFFIALGDEIRLTIVEALTEAASRRCGGD
                     YSMENLSLHGLNVKEITEYTSLSRPAVSHHLKILKDAGLISVRREGTCNYYYLSISQA
                     TLSLTGLGRRLQSFLNMKEEP"
     gene            47936..48148
                     /locus_tag="ACZPCR_03475"
     CDS             47936..48148
                     /locus_tag="ACZPCR_03475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaL family protein"
                     /protein_id="HIR1229979.1"
                     /translation="MKTKQTSKKRGGSCIFSLKEELRQIMTDMDCARNHFDQAVDPVL
                     IDCYIYEINAAQLRYQFLLRRIKNQE"
     gene            48207..49586
                     /locus_tag="ACZPCR_03480"
     CDS             48207..49586
                     /locus_tag="ACZPCR_03480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007706863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HIR1229980.1"
                     /translation="MTAWYTDSTFYHMYPLGMTGAPKNNPYPWPEEAPAPVSILPSAP
                     MEELLSWIPHLKQMNFTAVYIGPVFESSSHGYDTRDYRLIDRRLGSNAEFAEFVSQCH
                     ENGIRVVIDGVFNHTGREFFAFRDIREHGSSSPYIGWYKGISFDWRSPLGDAFGYEAW
                     RGVWELPCLNLQNPQVKEYLKDVIRFWISEFDIDGIRLDCANVLDFQFMRELRLLAEE
                     VKPDFWLMGEVIHGEYGRWVNSEMLHSVTNYEMHKSIYSAHNDHNYFELAHNVRRLQA
                     IGCSLYTFLDNHDEDRIASKLKDPNHLKVIYTLLYTLPGIPSVYYGSEWGIEGRRTDS
                     CDDALRPRILPSEARKQEDSELSSHIQRLGEIRKTFPPLHGGAYEELLLTNRQYAFLR
                     TAEDGSRLLTAANNDSCQASLTLPCPEANGCVRELLTGQSFPVSDGFLSFTLPPDSGY
                     VFCIGESSS"
     gene            49642..51543
                     /gene="glgB"
                     /locus_tag="ACZPCR_03485"
     CDS             49642..51543
                     /gene="glgB"
                     /locus_tag="ACZPCR_03485"
                     /EC_number="2.4.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006772765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HIR1229981.1"
                     /translation="MNKKIGMGFFGELDLYLFGEGRHYRLYEKMGAHPFTYRRQAGIH
                     FAVWAPHAEEVSVVGDFNGWNPGKTPMKRISGSGIFEAFVPGLKEGELYKYAISTKSS
                     SLLMKADPFAFYSEYRPGTASVTADISGFSWSDSAWMEKRRNQDPVKAPIAVYEVHLG
                     SWRKTNRPERDNCLTYREAARELADYVKSMGYTHVELMGIAEHPFDGSWGYQVTGYYA
                     PTSRYGMPKDFMYLVNYLHKKGIGVILDWVPAHFPRDAHGLADFDGEPLYEYADPRKG
                     EHPDWGTKVFDYGKNEVKNFLIANALYWIEQYHIDGLRVDAVASMLYLDYGRRDGEWV
                     PNQYGGNQNLEAVEFFKHLNSVLTGRRDGVMMIAEESTAWPKVTHQPEDGGLGFTFKW
                     NMGWMHDFLEYMKLDPIYRKFNHNKMTFGLTYASSEHFILVLSHDEVVHLKCSMINKM
                     PGSYEDKFANLKAGYTFMTGHPGKKLLFMGQDFGQLHEWDEKKALDWYLAEEPLHENL
                     QRYVRSLLTLYRKYPCLSRLDSDPEGFQWINANDGDRSIFSFIRRDETKKKNLLFIIN
                     FTPVAREHYRVGVPKRGNFTLVLDSGHGFYEKGDDVHVYRSKKGECDGQPFSFAYPLP
                     AYGAAVFRF"
     gene            complement(51591..52571)
                     /gene="rsmI"
                     /locus_tag="ACZPCR_03490"
     CDS             complement(51591..52571)
                     /gene="rsmI"
                     /locus_tag="ACZPCR_03490"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HIR1229982.1"
                     /translation="MEERRQEEHELMEQEALEWNEALREGTGWEQEKREDSSFGGKNG
                     QGKLYLCSTPIGNLDDITLRVLDTLKRVDLIAAEDTRHSIKLLNHFHIKTPMTSYHEY
                     NKVEKARYLVEQLKKGVNIALVTDAGTPGISDPGEELVRQCHEAGVELTSLPGPAACI
                     TALTISGLPTRRFCFEAFLPPDKKERQMILEELKRETRTILVYEAPHRLERTLAELFK
                     TLGERNITVCRELTKRYEEAFRTTFSGALSFYEDHEPKGECVIVIEGKSFDQVERERQ
                     QSFEEMTIAEHMERYLSQGMDKKEAMKKVAKDRGISKRDVYQSLLEEDGE"
     gene            complement(52640..53368)
                     /locus_tag="ACZPCR_03495"
     CDS             complement(52640..53368)
                     /locus_tag="ACZPCR_03495"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HIR1229983.1"
                     /translation="MLREGERIDALHRNGYRIIQNEKAFCFGMDAVLLSGYAVVKPGE
                     RALDLGTGTGIIPILLEAKTAGSHFTGLEIQDEMAEMAGRSVRLNGLEEKIDIVTGDI
                     KEAGRIFGAASFDVVTSNPPYMNDSHGLKNPELPKAIARHEVLCSLEDVVREGARVLR
                     PGGRFYMVHRPHRLIEIITAFTRHKLEPKRMKLVHPFVDREANMVLIEAVKGGRSMIK
                     VEKPLIVYREPGVYMDEIYDIYGY"
     gene            complement(53423..54331)
                     /locus_tag="ACZPCR_03500"
     CDS             complement(53423..54331)
                     /locus_tag="ACZPCR_03500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PSP1 domain-containing protein"
                     /protein_id="HIR1229984.1"
                     /translation="MINVIGVRFRPAGKVYFFDPAGMDIKTGDHVIVETARGIEFGHV
                     VLGSRAVDESKVIQPLKPVIRMATAADEETERRNKEKEKDAFGICLEKIKKHNLQMKL
                     IDAEYTFDNNKVLFYFTADGRIDFRELVKDLAAVFKTRIELRQIGVRDETKIMGGIGI
                     CGRPLCCHTYLSEFIPVSIKMAKEQNLSLNPTKISGVCGRLMCCLKNEEETYEELNSK
                     LPNIGDYVTTDDGLKGEVHSVSVLRQLVKVVVTVGKDEKEIREYPVESLKFRPKRRRE
                     RVSVDAELKQLEALEKREGKSKLDNN"
     gene            complement(54336..55325)
                     /gene="holB"
                     /locus_tag="ACZPCR_03505"
     CDS             complement(54336..55325)
                     /gene="holB"
                     /locus_tag="ACZPCR_03505"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007870546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HIR1229985.1"
                     /translation="MAGFKDIIGHEMIKDHFQKAIEYHKVSHAYILSGEQGMGRKTLA
                     KAFAMTLLCERSDKEPCMECHSCKQILSGNHPDVIWVTHEKLNSIGVDDIREQINDTI
                     QIKPYSSAYKIYLVDEAEKMTVQAQNALLKTIEEPPAYAIIILMTTNEETFLPTILSR
                     CIKLKLKPLKDQTISSYLTESMGISENQADVFAAFARGNLGKAIHLASSEEFKLLYRE
                     VLTLLKNVKEMDIAMLLDYIKKMQEENLILDECLDFMQLWYRDILMYKVTKDMNCLIF
                     KEEYTAVSRLCQNSSYEGLEAVLNAIDKAKARLAANVNTELALELMLLTMKEN"
     gene            complement(55620..56207)
                     /locus_tag="ACZPCR_03510"
     CDS             complement(55620..56207)
                     /locus_tag="ACZPCR_03510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002605439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside/nucleotide kinase family protein"
                     /protein_id="HIR1229986.1"
                     /translation="MGKSASGKDTIYKKLLEYFPELKTVTLYTTRPMREGETEGVEYH
                     FIREEQLEAMKSEGRVIEMRTYQTMYGPWSYATVEDGQIDLSQGSYMMIGTLESYESI
                     RTYFGENGAVPIYIEVEDGERLIRAVNREKQQKNPKYTELCRRFLADETDFSEEKLAQ
                     AGITAEERYENQELSDCLKNIAGKIEKTIRRYARG"
     gene            complement(56304..57830)
                     /locus_tag="ACZPCR_03515"
     CDS             complement(56304..57830)
                     /locus_tag="ACZPCR_03515"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006772539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HIR1229987.1"
                     /translation="MKLIDRLKEYGESDFYAFHMPGHKRQEELGITLFPNPFSVDITE
                     IDGFDNLHHPEGILKESMERAAAVYGVDRTYYLVNGSTCGILAAISSAVSDGKKLLMA
                     RNSHKSAYHAAMLNRMETEYIYPEIIEESGIQGGIEPGELRRILEADKENRIGAVFLT
                     SPTYEGIVSDIKSLAEIAHERGVPLIVDEAHGAHFAFYEGEGENRQTGRLFPRSALQC
                     GADLVIQSVHKTLPSLTQTAVLHLKEGITDRERLEFYLRIYQSSSPSYVMMASIDNCI
                     EYMAGEGRKRLEQLGRRLEHWMEDAKQWSCLRVLDDHVLGENGAFDRDISKLVVGISP
                     QAEKAGINGTALAEAVRRRFHLEPEMCCDRYVLYMTSLMDSEESLFKLSAALTKIDEE
                     IAGALCMGRNEGTEGTSEETEKYSGKQGTLTWTRDVPRRISMAEAVSKKGRRIRLEDA
                     CGCISRGFLTVYPPGVPAVVPGEMISQETAELLLKNAGLGLTVEGLDSDGSIDAVKDE
                     "
     gene            complement(57870..59801)
                     /locus_tag="ACZPCR_03520"
     CDS             complement(57870..59801)
                     /locus_tag="ACZPCR_03520"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1229988.1"
                     /translation="MRKQTVLEKTAGQVRNGIQDEYEDLYILTVEEVFQAACAAVRKE
                     QSEELLIKFYLELFEQKEMLPESDENIRRYVREMVFHLAGSAPESEEEGIPKGEQIGE
                     SQAAELWLQIEKRLGWSGEDGDGVFDDEDTSSSGLEAYVKGFIRVVFTVALVGGILIF
                     LCRNVIGVISARKAEQTAAQMQQDDGWKDVYSERREKDKEEEQEELLRSAFFEQKDGR
                     LFLMTADGPLRREKICHGKQILSFAEDGALEKIEKNSQADSQNPSAFNGEDQYFIKNG
                     NIYIQEGRSGRENCVVGNGHIVWMDCRCQSLWYVCSYQIPNSDQIKMTAFRSELDGDS
                     EEELITDSLLLKKEGLQFSKDWIYYKSGNSVFRKSMDGLRKEKMAEADGEYFAFGDTV
                     FYMDGDDVRSVSKGESDYQENGEFQVSIEDGSIVFTDEEGEPAVPDENGEIRFGDRIY
                     SMSGNRVANVRQADIVHEGTVYYLDDPDGQRKIYRNSQDDSFTGLMPQNGIRTDSLCL
                     SGSWLYYSACMEQIGGVQYSQIYRVNLENMAQEKVGRLFQGVVTAMYASSHENRIYGE
                     YIDSVKNGEIHGSICAITENGELGIIEDSVPRSQGNDRLQFAVSGGDKIYCFYHTCTY
                     DSESGVIRDISTQAVEIEW"
     gene            complement(59978..60988)
                     /locus_tag="ACZPCR_03525"
     CDS             complement(59978..60988)
                     /locus_tag="ACZPCR_03525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HIR1229989.1"
                     /translation="MSIRYKGKRFLAALAAACMIFGTAPVQRVMASPAEDGAKAPAEI
                     SAQSRQLGTGSQGQDSAADTYLGGASLTMLAPQTDGQNMSFLLQTNQGEVIVIDGGLD
                     QDADHLVETIQAMGGRVSAWLITHPHSDHVGALTNILNRNPIPVQIDQIYCSFLTREQ
                     YEKGDHMGRMSDYDNLMAVFSRFPAEKLHMQLIRGQKITVDNAEITVMNEPLYTDYNT
                     FNNSSIAYRIDINGKRLMFLGDMGWEPGTRLIRMWDYKDLKSDVVQMAHHGQDGAEEN
                     LYQVLHPEICFWPTPAWLWDNMKDGVAGAGSYKTMKTRSWMERMGVARNYVAKDGDLV
                     LR"
     gene            complement(61294..61366)
                     /locus_tag="ACZPCR_03530"
     tRNA            complement(61294..61366)
                     /locus_tag="ACZPCR_03530"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(61331..61333),aa:Lys,seq:ttt)
     gene            complement(61387..61459)
                     /locus_tag="ACZPCR_03535"
     tRNA            complement(61387..61459)
                     /locus_tag="ACZPCR_03535"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(61424..61426),aa:Phe,seq:gaa)
     gene            complement(61518..61591)
                     /locus_tag="ACZPCR_03540"
     tRNA            complement(61518..61591)
                     /locus_tag="ACZPCR_03540"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(61555..61557),aa:Met,seq:cat)
     gene            complement(61651..61732)
                     /locus_tag="ACZPCR_03545"
     tRNA            complement(61651..61732)
                     /locus_tag="ACZPCR_03545"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(61696..61698),aa:Tyr,seq:gta)
     gene            complement(61755..61827)
                     /locus_tag="ACZPCR_03550"
     tRNA            complement(61755..61827)
                     /locus_tag="ACZPCR_03550"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(61792..61794),aa:Thr,seq:tgt)
     gene            complement(61836..61908)
                     /locus_tag="ACZPCR_03555"
     tRNA            complement(61836..61908)
                     /locus_tag="ACZPCR_03555"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(61873..61875),aa:Val,seq:tac)
     gene            complement(61938..62011)
                     /locus_tag="ACZPCR_03560"
     tRNA            complement(61938..62011)
                     /locus_tag="ACZPCR_03560"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(61975..61977),aa:Asp,seq:gtc)
BASE COUNT        14504 a        17872 c        12784 g        16967 t
ORIGIN      
        1 tttcttttaa aatcacgggc ggaggtagta gctatgagca tttttgaata tgatgaagaa
       61 cgggaacggg agctgattaa aaaggcggag tttgaatccg gaaaggaaga gggactgaag
      121 ttgggtaaag ctcagggcat tgaattaggc aaagctcagg gcattgagct gggtaaaatc
      181 cagggtatcg cagccttaat tcaggctttc caggatctgg gcgcttccag ggaagcagct
      241 cttctttctt tgaaaaagca gttttccctt tctgaagagg aggctgaaag acagctgaat
      301 caattctgga agtaaaacag caataaaaaa gaatgttttt cccattcact cttagtgata
      361 tgaaacagaa aaacattctt ttttattatc ttattccatt acctgaacct tcaggcttga
      421 tccgctttct atcagttttt tcatttcgta atacccgtct gtctcagttc ccatgagggc
      481 aacgaaaaag aaaccttctc ccgacaccac gagagtatct tttgacgcaa tgaccgtatt
      541 gacatttctg taatcgtagg aagtaatata ctcctctgtc tgaaccttga aaccattctt
      601 aaaaaacacc agatcttttc tcatcccgtc tgcttttcct tttatctggt tccattcctt
      661 ggcagctgcc tttctcaggg ctttttcact tctggcctgc ttatttttca ggaaataatg
      721 tgctgcgcag actgcggcaa acaccgcctc tactgtcagg taaatgccaa acggaagcgt
      781 aatttccttt aaagtcatat tgataaaggt gaacgccgcg ctgacgcaga gaaataccat
      841 caaatacatg ctgacgggat acttctctct tccggactga atccggttcc actctgccgc
      901 cttatataag cggtaaatac catcctcgct ctccagaact tcggctctcg gcgcgtcctc
      961 cttcagctcc agagaagcct cctctgccat ttttccccga agaaatgatt caaaatcatt
     1021 gggattgccc tccagaaaat ttttcttttc cagaacaatc cgttttcctg cttccatatt
     1081 caggataaat cggctgtttt cacattccag gctttcgatc ctcctgtaag acacatccaa
     1141 tctggaatca tcggattccg taaacatact gccgtcgcca aaccagagat actggcggaa
     1201 tgaatggcga aactgcggat ttcctgcatt tttctttgat gtgatccagg cagacaggaa
     1261 aaatatgcct ctggatgcca gatagaataa aattcccaaa aacggccata tgataattct
     1321 aacaatgccg ctctcaacct gaaaatgatc gcacagcttt acagaaagaa acatggaaat
     1381 tccagtccaa atcagaatct ccagccatcc gtaaggctta aatgcccctc tgacgaccat
     1441 gtctctcgcc acatccttcg cctttcctga tatgaagcca tcctccggat cgtggaagac
     1501 atgaaaatat cctttgctca tcctaaaact ttcctcctat gaatagtttc cccctattat
     1561 gcagacaaaa tgcaaacccg cgctctgcgc ttcctgtctg cttcgcagac gcctgctttt
     1621 ctgctgatgt ggtacattat atcacacttt tttctatccg cccaccctat ctgtgaaaat
     1681 tgaaatgtgg cgaaggcctt cccgcccctg caaatgaatg gtatactggt atcaagaaat
     1741 gaaacagaaa ggaacaggta tttgactatg gcaccatacg attcctatag aaacagaggc
     1801 cgccggaacg gaaacggcgg cggacgcgga ggagacaata gaaacggcag ggaagccggc
     1861 cgaatctcca ccccggacag acccagagta ctgaaggcct ctgaggagct tcggactctc
     1921 cttctctcca ttgaccataa aagctacccg gcctacaagt ctttggccgg tatttaccgc
     1981 tttcccggtt ttcagctttc cattgaccat gtgcaggggg atcccttcgc ttctccttcc
     2041 catttaagcg tgttcgtccc gcacaagacg gcaggcttcg acgcctctct ctacggcacg
     2101 gacgccagaa aaacggcgct tgaggattat ctgatccgcc agtttggaaa ggaagcggct
     2161 cattttaatt tccaggccaa gggttccggc aaaagcggcc tgatttccgt cacccgctgc
     2221 ggacaggaaa tcctgtcccg aactgcctgt gaaatctccg gggatggcgt ctggctccgc
     2281 ttccatgccg gcttcccggc caatggccgc acaattaacg ccagagagct ggaaaaaatc
     2341 ctcttcgatt ttattccggc ctgcgtcaga aaatctctgc tctgcgcctc tcttcccgct
     2401 gacgagatcc aaaagagggc ggatctggcc gatgatcagg agtttatccg cagcgaactg
     2461 gaacgattga atctggcagc ctttgtggcg gacggttctg tccttccaag gcagagcgga
     2521 gtgtcggatc tgccgttaaa aggctgcgtt tccttccagt ctcctgattc tctccggata
     2581 gagctgaccc ttccccataa gggcgtcctt accggcatgg gaatcccgaa aggcattacc
     2641 ctcattgccg gaggcggcta ccacggcaag tccacccttt taaaggccct ggaaatgggc
     2701 gtttacagcc acattgcagg ggatgggcgg gagtatgtaa tcactgattc cacagcagtc
     2761 aagctgcggg cggaggatgg acgctgcatc gaagacaccg atatttccct gtttatcaat
     2821 gatcttccaa acggaaagga cacctgccat ttcaccaccg aggacgccag cggatccacc
     2881 tcccaggctg ccggaattgt ggaaggcatg ttctccggct gccgcgcctt cctcatcgac
     2941 gaggacacct gcgccgccaa ctttatggtc cgggacgagc tgatgcagca ggtcatccac
     3001 cgcaaaaagg aacccattac cccgtttatc gagcgggcca gacagctgtt tgaaacatgc
     3061 ggtatttcca cgatcctggt tgccggaagc tccggcgcgt ttttccacat cgcggacaca
     3121 gtcatacaga tggacagcta ccgccctgtg gacattacag gcaaggtaaa ggagacgtta
     3181 aacgccttcc cgtctccgct gaaatcccag gaagaagccc cggctttccg ccttccagag
     3241 ctttcacggc cctaccgtgt caatggaaaa cgtgtctcgg acgcaaaaat caaatgcttt
     3301 gacagagatt ccttctccat tgataaaaac acggtaaatc tccactatgt agaacagatc
     3361 gcagattctg agcagacggc ggctctggcc tacgttctcc ggtacgcctg ctccgtcctg
     3421 gcagacggcg aaaaaagcat tgcccagata gcggacgtgc tggaagagat gtgggaaagc
     3481 gaaggcttct cctccttctt aaagaaaagc aagggaggcg gctacgcggc gtccggcttt
     3541 gcacgcccga gaaggcagga ggtctgcgcc tgcctggccc ggtacagaaa ataaacaaaa
     3601 aatggcaaaa gaagaggagg ctctattcca gagcctcctc ctcttttgcc ctcgctcttc
     3661 tgtccctgac agactggatg acgggaacca tgaaaatggc caccattcct ccggcgaagc
     3721 cgttgttata aagattcatt cccccatata caattcccac gtttaaggcc accgaggagt
     3781 ggaggaaacc ggccaccagt ccggacagcc agccaaattc tcctgagatg ggagccagcg
     3841 tggtggaaaa gagaaacgct aacatcggcg acggatcgct gatattccac cgcttggtaa
     3901 gccctgccag atacacgccc gccatgatgg gaaatatatt gcggatgtgt tttccagtgg
     3961 agctgaatcc cacaatagta aaaattcctc cgatcgtagg cccatttaaa tcgcctcctg
     4021 caatcagcac cagaagcgtg gccataaagc cgtttaccgc catatttaaa acggtggcag
     4081 gaccgccgtt gtccctcagg taatccgaac cgccgtggcc ggagctgtga agaattttcg
     4141 aatattcctc caccacgccg cgccctccga agtaaaaggc tcccgcggcc atgccaagaa
     4201 aaaggattga tagaatagta aaaaacagga aatcgcttcc tgtgtaccag atcagacggc
     4261 tctccactgt gattccgaac gatttcagga gagacacgat aaccgtggca atgattcccc
     4321 cggcgaagcc tacattgtac agggaatatc cctgatgggc gtggtgaacc tgagccgcca
     4381 gaggcggaag cagaaatccg atcgttattc ccgccgtaag agccaggaaa aacctggctg
     4441 caaccggaag atctccgatg tgcatcagct gtgtgataat gggggacaag ctggttccgt
     4501 aaagccccac atagacataa tgagacatgt gggttttatg atatttggcg taaagccaga
     4561 tacccagcat aatcgcccag atattgaaca gattttttcc aaacagggaa aatccaaaca
     4621 tcaggcaggc ggacgtgata gtatgtccgt ccatctccat atccagaaaa tagataaggg
     4681 caatactgag aagcgtgaga acgcctgcgt tcagaaaagc ggctcccact ccgcctacca
     4741 cgaaatagtc ggtaatcagg aaatccggct ccttgatcag cgtagctatc ccgggccaga
     4801 tctccgaaaa gggctggaga ataaagccgc agacaataaa gtaaacagga atcagagaca
     4861 aaagaaggaa tttatctctt ctggtcagaa tccttttgtg aaacatttat gcacaacctt
     4921 tctatatagc atctcctctc attatatatg attttaaaaa atttgaaaat aatataatta
     4981 ctggtttttt tgtatattta atcattctga cagctttaca atcaccgtgt cctcatccat
     5041 tctgatgctc cccttctccg gataactggt catttcccct gcaaaaggca gagaatccag
     5101 gtatctggag agcaccggct cctcggacgg cagctgcagc gtctgcatca gatcgtaaat
     5161 tcttctggaa attcccatgg gactttcagc gtcccactgg tagaaggaac agccgatcac
     5221 atcacctctc agggcttctg agggaagctc cgcctcccgt ttccccagaa aaataaacgt
     5281 gcagtcctcg atgtctcttc cttcctcctc tgccgtctcc ccggcctttt catagatttc
     5341 ccgcgtcagg ctgatatcct gctccgatac ctgatggatg gtctcaaaca atgcggctgt
     5401 gtccttcgcc tggctccacg aaataagaag gcacagagct gctgccgcag atgcggctcc
     5461 ttttctccac cgaaccgctc cttttccttc ctctggccag agaaaagccg tcaggaagga
     5521 gagagcagag gcgaatacca ggggatatac caggtgggca cggataggct ggtaataccc
     5581 tgccacaagg gtcattaaaa acggagacag caaaaagacg cataccgccg ccagatacca
     5641 tagctttccc ggcctttttc tgcacctcat ccacaccagg gatgagataa aaaataagag
     5701 aaccgcccag ccgaactccg gccggaacat gacgtagtag cagtcgaaca cccgcctgag
     5761 ctctcctgca atccagtgga cgcagacgtt aaatccgtcc tttttccagt gcatcatatc
     5821 tgccacatag gcctcgctgc ctccggacag cgtgcggact gccgcggcgg ccgccatgta
     5881 aaggacaaat ccaatgacaa agacagccgc cagcttcacg cctgccaaaa gccagccaaa
     5941 ccgctgcctg tcctgttctt tgccattttc ccccagataa acggtcataa aaaggatcac
     6001 aatcagagac gccgccacag ccgccatggc ctggtacgtt ccaaaggccc aaaccagaag
     6061 aagaatcgag cctgccgccc agaaccattt tcctccaaaa aaggcaaatt gtccggctcc
     6121 gtatgccgcc aggacgcaga gcagcatggc gaaaaccacc tccgccgact gcagcacaaa
     6181 atagagctgc tccgcgaagc agggagcagt cacataaaca accggaaaca cagccgaaaa
     6241 caggcggaat ctcttctgtc cgccgctcca cttatgcaca aaaaaggata aaaccatggc
     6301 tgttatccac aataaaatca cagtaagcac acgggagatc acaggatgaa acgcagcctg
     6361 gccgaacaga tgcttggtaa ataccaggcc aaaccggtta attcccagcc atgaattcat
     6421 catggcgtcc ggatctgcca tcataatctc tgtgtcaacg gtaatatcct gcctggtcat
     6481 ccaggcccca tacgtacaga gggcggccgc tcctgacagc aaagcgcccg ccctgttttc
     6541 tctgataaaa gaaagaaatt gaaacgccat tattcctccc ccttctctct taaatcgtcc
     6601 tttaaattat cttcagccac tagatagaga ggtctgtgct tcacctccag ataaattttc
     6661 gccagatatt ttcccacaat gccggcgcag agcagctgaa tgcctcccac aaacaaaatg
     6721 atacaggcga gagacggcca tcctcctacc ggatccccga acatcagcgt cttggcgatc
     6781 accaccagca ccatgaaaaa ggctaccaga caaaaaatca gccccagata ggcagcgatg
     6841 gagagaggca gcgtagtgaa cgccacaatt ccctctatgg aatagattaa aagcttccag
     6901 aacgaccact tagtctcccc cgccgcccgc tccacgttct caaaggggat ccacttggta
     6961 cgaaagccca cccagccgaa aatccccttg gaaaaccggt tgtactccgt catggacaca
     7021 atagcgtcct tcatttttcg gttcatcagc cggaaatccc tggctccgtc cacaatatct
     7081 atgtcagaaa ttttccggat caggcggtaa aacatcctgg caaaaaagga acggatggga
     7141 ggttccccct tcctgtctac ccgccttgta gccgcgctgt catagtcccc ggactctaac
     7201 gcctctatca tctccggcag aagcccgggc ggatcctgga gatctgcgtc cataacggca
     7261 gtataatccc cctctgcagc ctccaggccc gcatagatgg ctgcctcctt gccaaaattt
     7321 ctggaaaaag aaatatattt tatccgtgag tcctcctttg ccctctcttt taagagtgaa
     7381 agagttccat ccctggagcc gtcgtccacg aaaatccact cgaattcata ctcagaaagc
     7441 cccttgcata ccctgtcaat ctcctgaaga aataagggca gcgcctcctg ctcgttaaag
     7501 cagggaacaa tgattgaaat ctgtttcatt ttcgttttcc tttaaaccct tttgtcaatt
     7561 gattcatcct ctttttatat catatctggc aggcggttac aagtttattt tgcggcggaa
     7621 gttttccttc acagaccaga aagtatagat accgccggat tcagagcgta tgcgtggcca
     7681 gctgcgtttc cggctcggtt cgcgctgcga aagtctcgct atcgccactg atacgctctg
     7741 aatctggctg tcatactgca ggtccaggct tactgagagg agaatgacag ccagccttaa
     7801 taaatcctct cgtccccctc gcacctgata atattggggc attctccgta aaccagactg
     7861 tacaccggcc tctgcccctc gtattttcgg atttccgcct gaagcttctc cttcatcttc
     7921 tcccgatctc tgggaagtat tcccctcacc cgaaattcaa taaaatcatg gaaaccgtcg
     7981 taggaaatgg gatattcctc tgttcctgcc ctctcgatca aactcagctc ctctttcagg
     8041 cactccagct cgtccgcctg ggtaaatgtg ccccgctctg cctctctgta aagcggaacc
     8101 tccttgtgga ggaacatgga aaagttcacc acatgggcag gatgggtttg attcagaaac
     8161 ctggctaaag ccagagcatt ctcctctccc ctgccttttc cggccactcc cgtcataatg
     8221 tgcgcgtcaa aggtaagacc tgcctcctga agccgtctga tggcctcata ggcctcctcc
     8281 agcgtgtgat ccttgttcat aaacgacagc acgtcgtcca ggcctgtctc gattcccagg
     8341 tagagatggc gcgcccccag cccgtacagc actctcagat cctccctggt ctttttcagg
     8401 attcctgtca ccgtagcgtc catattgatc atgccgcact ggggaaaata tgattttaca
     8461 agccgtaaaa tggccgacag ctcctccatg ggaaggtcaa aggcattccc gtctcccaga
     8521 aaaatccgtt tcgggctgcc gccgcaggct ttcactctct gcagctctga ttctatctgt
     8581 tccacaggca gctttctgta ctttaaatgg cggaacaggt tgcagaattt gcatccattg
     8641 taggaacagc ccaccataac cggaagcata aacgcgctcc tctccatcgg cgcccggcat
     8701 atctgtcctt cgtaattcat aacacccctc cttttagaaa aagtatatca cagatttgcg
     8761 aaagcagcga taaaagacag aaaagcccgc cacatctctt tttcctgaaa tgtgccggac
     8821 ttctgcattt tctgtttatt ctctgtctat tctatgttta tgttcggttc tcttgtgcgc
     8881 tttttctgtc ctctactgaa aaatcataca gactatgacc ataactgccg ccgccaggta
     8941 aagggcctgc tctgcctttg tggttctgcc ctctgtaaat cttccgctct tttccatagc
     9001 cagaagtcca agctcaaaga taatgacagc ggctgccatc agtccgaaag ccgcctgcat
     9061 acctgtcatc tggaaaaata tcataaccag aaacagtacg cctgagatta catgcataaa
     9121 agaaagattg attttttgtg tcatagaaat ccccctctct gaatctgttt cagttttatc
     9181 ctgcgtatca ggttttgtcc tgtactgcca ttatatttca caatttttcc agattcaaga
     9241 gggggcgcgc cggtttaagg attgcgaaaa tgatttgtaa gcttttcgaa agaaactgct
     9301 ttcgccgttt actgtttatc cagccccaga ttcttaaacg cctctgcgaa tggattattc
     9361 accatttttt cttcctggtt ctgcttattc agatactttg ccacgtctcg ctttgtcacg
     9421 cctgcgcctt ccttctggcg gcgttccttg aagtttgaca gcttttcctt atagccgcag
     9481 gagcaggaga aggtctggtt ctctcccttg cctctcagct ccatcttctt gtggcacttg
     9541 ggacatctgg cgttggaggt gcgggaaacg gtttccctgt atccgcattc tctgtcctgg
     9601 cacaccagca tctggctgtt ctttcccttg acggaaagca tccgttttcc gcagcgtggg
     9661 cattttgtat tcgtcaggtt atcgtggcgg aaggttccct ctcctccctt gatctccccg
     9721 atcagctcct ccgtgtaggc gcagatatct cccataaatg cgtcccgctt cagctctccc
     9781 tttgcaattt tagaaagctt catttcccac tctgccgtca gctccggctt ccgaaggtcc
     9841 tccggcacca gctttaacag ctgtttcgcc ttggaagtca ggaaaatatc cttgccccgt
     9901 ttctccagca taaagcttga gaacagcttt tcaatgatat ccgccctggt ggccacggtt
     9961 cccagtcccc ctgtttctcc cagggttttg gccatggcct tatcgtgaga ttccatgtat
    10021 ttcaccggat tttccatggc tgagagaagg gtggcctcgt taaagggagc agggggcttc
    10081 gtttttcctt ctgtcaggga caatcccgcc ccggcaatca cagcgccttc ctttatgtca
    10141 ggaagcgtct gttccttcac cctcgcagcg ccgcctctct cctcctcttc gtctgtctcg
    10201 tcgtccaggt catcgaaaga aaggaatgag ctgtctgccc cgctgtctgt gcctgcagac
    10261 gtctcgtagg cctcccgcca gccctgggat cgcatcacct ttcccctggc tgtaaaccgc
    10321 tggccgccta tctctgccgt aataaccgtc tcgtcgtact ctgccgccgg aagcagaacc
    10381 gccagaaaac ggcgcaccac cagatcgtag attttcctct cctccacagt catatgctgc
    10441 agctggacga actgctccgt agggataatg gcgtggtgat cggatacctt tgcgtcgttg
    10501 ataaaggccg ctttcttcgt ccaggtctgc ttggacagac gggcagccag ctttctgtag
    10561 gggccggtgc cgcaggctgc caggcgatcc tttatggtat ccgccacatc gctgctcaaa
    10621 tatctggaat ctgttctcgg ataggtgagt accttgtggt tctcgtagag cctctgcata
    10681 atgttcaagg tctctttggc agagtagcca aacctcttat tggcctctct ctgaagctcc
    10741 gtcagatcgt agagcagcgg ggccatggtc tttttcggcg tccgcttgac ctgcacaatc
    10801 ttcaccggct gatcacgaag ctcctttaag agtctctcca tccgctctct gtcaaagctt
    10861 ctcatgccgc ctgatttctg atcctgccag gtcagggaca gagaaggact ggaggttctg
    10921 gcagtcagcc catagtagga tttcggcctg aaatttctga tttcctcctc tctccccgcg
    10981 atcatggcca gggtaggcgt ctggacgcgg ccgcaggaca gctgggcgtt gtacttgcag
    11041 gtcagagctc tggtggcgtt taagcccacc agccagtctg cctccgcccg gcacatggcg
    11101 gcatcccgga gacagtcgta ctccctgccg tccctgagcc ttgaaaagcc gtcctttatg
    11161 gccttatccg tgacagagga gatccagagc cgcttaatcg gctttctgca gcccgccttc
    11221 atcaggatga acctggcgac cagctccccc tcccgtcccg cgtctgtggc gatgacaatg
    11281 tccttcacat cgtttcgaaa cagctggcgt ttcaccgcat taaactgctt cgctgtcttt
    11341 ccgatgacct ccagtttgaa aggtttcggc atcatgggaa gagtctccat tttccactct
    11401 ttgtatttct tatcgtaagc ctccggggcc gccagctcca ccaggtggcc taaggcccag
    11461 gtaaccacat atttctcccc ctccaggcag ccgtccccgc tctttttgca gtttaatacg
    11521 cgggcaatgt ctctgcctac ggaaggcttt tctgcaataa caagtgattt catgataaac
    11581 gctcctccaa aatccgtctc agctcgtcca ccacctggcc caggtccttg ccctcctcgt
    11641 ctatggtaat gtccgcatac cgctcaaagt aggcggcccg ctcctcatag agatccttta
    11701 aggtcatgcc ctcctttaac actacacctc ggtctacaat atttcccagg cgcttcgtca
    11761 gctcctcata gctgattttc agatagacca ccaggccgat ttcttttaaa tgggccatgg
    11821 cctccgctcc gtagatcacg ctgcctcccg gggcgatgac gctctgctct gcctgcagag
    11881 ccgcgttcac acggttttcc accgccataa agccgtccat cccctcctgg gcgatgatct
    11941 cctttaacag ccgcttttcc tgctcctgga tcacaatatc tacgtccaca aaggaatacc
    12001 ccagacgctt ggccaaaagc actcccactg tgctcttacc ggccgccggc attccgatga
    12061 gcgttacgtt gtccgccttt ttctgttctc tcatttcctg tctctcctgt cgcttcctgc
    12121 ttttcctctg tctttccgcg cagttcctcc gtttgctctg tttttcagcg gagccttctg
    12181 tttctcaggc tggcttccac gcttttctcc cgctttcttc ccgctttttt tcttctgcac
    12241 agaatatccg aattttccga gttttttacc taatttaaaa tattccccgt gggaatagga
    12301 taccagcccg gcctcgttca gatggaaccg gcctgtctcg tccatatatt tctcgtccac
    12361 cgtcacattg acaatctctg ccagaaacat gtcgtggctt cccagcggaa tgatctgcgt
    12421 cacccggcac tccaggttca caggactttc ctcaataccc ggacaccgta ccttctttga
    12481 tttgagaggc gtcagcttca tatccttgaa tttatctgta tcccggcctg attttacgcc
    12541 gcagtaatcg gtggcaaagg tcagatcctc tgtcaccaga ttggccacga actcgcctgt
    12601 ctctttaata atgtggtggg aatagcgatc cggccggatg gacacataga gcatggccgg
    12661 ggaggaacaa gtggtcccgc accaggccgc tgtgataatg ttgggcttcc cgccctcctt
    12721 ctggcagctt accataatta ccggcacagg atacagcata tttcccggct tccagtcctg
    12781 ttttgacata aatctctcct ttttctactg ttctgtggcg atcatcagcc ccggaatcag
    12841 ctgcttcttt ctggaaacga cgcccggcag cttcaccacg ttggcggcct cccttaaatg
    12901 aaaggcagcg gcggccagct gttccgcacc ctgtccgtcg cagatcaaat ctgtggactg
    12961 ctctaagata tttgtcatca taaagaacat catatccacc ttctgctcct gtctggcctc
    13021 gccgatgtac tttaacagac gctctctcag cttctccagc tcctccgcgt ttaaggaggt
    13081 aatctggccc actccgaagg tcagcttccc ggcggtaaaa cgcttgaaat cctgataaaa
    13141 gatctcggaa tctgtctttc ccttcagctt gcttccggct tcaaacatct ccttggcaaa
    13201 ttcctccgcg tcaattcccg cgatctgggc cagattcagg gccgccgcct ggtccatggg
    13261 cgtgcaggtc ggggagcgga ataaaagggt atcggaaatg atggcgctgc ataaaagccc
    13321 ggctgtcttt ctgtcgatct ccaccttatt ttcgttgtac atctgataga taatggttcc
    13381 cgtacatccc aggggctgat tcctgaagaa taccggggac atggtctcca cggttcccag
    13441 cctgtggtgg tcgatgattt ccagcacgtt ggcgctgtcc atgccctcca ccgcctggct
    13501 tctctcgttg tgatccacta aaatcaggtt ctttcccctg gctcctaaaa ggttccggcg
    13561 ggaaatcatg cccttatact ttccgtcctt atcgagaatc gggaaatccc ggtggcgctt
    13621 gcttgccatc acatccctga tatcgtcgat aaaatcgtcg gttccaaagg taatcaggtt
    13681 atcctttgtc ataaagtagc tgatgggcat actctggtta atcaggcggg ccgctgtgta
    13741 ggtatcgtag ggcgtggtga gcacggtgca tcccctctcc tgggccagct ttttaatggt
    13801 catggacacg cccgctccct cgcagacaat aatgcagctg gcttccatct caatggcgca
    13861 cagctgggat tcatagcggt ttcccagaat caccagatcg ttcttctcaa tgtaatactc
    13921 catcatgtca ggattggcgg ctgctaccag cacctttccc tgatcaaagt aggcgttctc
    13981 atcgcctacc accaaagctc cctccagagt ctccagaata ttggaatact gggtgcaggc
    14041 cttggagaga atgctgctgt cgtagacgtt catgtaggat ctggtaatgt ctcctactgt
    14101 gatcagcccc tccaggatat tgtcctctgt cacagccggc agagtcacca ccgtattgtc
    14161 ctgcatcaga ttccaggcct ttttcaggga aatattcttc tgaacgcccg ctgtctcccg
    14221 gatctcaata tccttcacct gagtccgcac gttttcaata agcttggggg cttccactcc
    14281 aaaatagtcc agtacgtact gtgtctccga attgacgtgg ccggctctgg ccggggtaaa
    14341 tttctctcct gtcaggatgc gcttcagatt ggcgtagcag atggcagaac agatggaatc
    14401 cgtatctgga ttcttatgtc caatgacaat ggtttttcgc tttttgctgt cgctcatatg
    14461 gtttcctccg cctatgtttc atacattgtt aatatgctat tcataattta ttcacaatta
    14521 ttttttatac taattgtata aaaaacaaag cgtataaatc atttttttat ccgatttgca
    14581 tatagatttt tcataattcc cccggtcatc ttcggatgcc gggggctcct catttctcag
    14641 ggctgttttc tgcctgagcc tgttttctct ccgttcctag tccagaatca gtctggccgc
    14701 cccgtaaatt ccggcgtcgt tgcccagctg cgcaagggtg atctccgcct tctggtcaga
    14761 aagggtggta aactggtcga aatatttcct gattccctct gtcagaaagc tgcctgccct
    14821 ggacacgcct cctccgatga caaacacctc cggatctacg gtcatggaca caacggacag
    14881 agcccagccc aggtagtaga atacggtatc catcacgcgg caggccatgg cgtctccggc
    14941 cttcgcgcag tccagcacgt ccttggcagt gatatctgcg ccgaattttc tcatctctgt
    15001 gtcagagctg tcctgctcca tggctcttct ggcttccctg gcgattcccg tggcggaggc
    15061 cacctgctcc agacagccat agccgccgca gttgcacggc tccttctccc cttcgcggat
    15121 gcgcagatgt ccgatctcgc cgccggttcc gtgctttcct gcgactatct tcttatcgag
    15181 aatcacgccg ccgcctacgc cggttcccag agtcaccatg acaatatcgc tgaagccttt
    15241 tcctccgccc tgccacatct ctcccagagc ggccacgttg gcgtcgtttc ctgttctgac
    15301 taaagcgccg tctaacaggg cgctcagctc cttctgcgga ttcttattct tccagcccag
    15361 atttacgcac acgcctacga agccgtccgg catcactggc cccggaaggc caagtcctgc
    15421 tccggccagg tcagaaagag aaaggcctct ctctgaaagc ttctccttca cagaggccgc
    15481 tgcgtcagga aggataaacg ccccgtcctc ctccttcctg gtgggaatct cccacttctc
    15541 catcagggtt ccgtccatct caaacagacc aagctttacc gttgttcctc ctacgtcgat
    15601 tccgatacat ttttttccca ttaaaaagct cctttatcta taatgccttt atctttgttt
    15661 tctgttttcc agtatacaag aaccgtgttt tatttgcaag gtgcgtttgc cgtaccggcg
    15721 tcagtcaggc gctggaatct acgcgctgga atctgctcac tggaatcagc gcgccaaaaa
    15781 gccaaggggc cggcacttgg tcagtgggcg gctccttggc tttccatttt aaacattatt
    15841 tctgaagttt tttaataatc tcttctgtat attcgcttgt ggaagcagtt ccgcggagat
    15901 cctttgtcag gcagatcccc tcctgaagca cctcgtccac cgcctccctg atcctggcgg
    15961 cgcactccgt ttcgccaata tactctaaca tcatgcaggc tgaccagaga aaagctgtgg
    16021 gattggccag attctttcct gcaatatcag gcgcgcttcc atgtactgcc tcgaacatgg
    16081 catactctgt tccaatattg ctggatggaa ccagtcccag gcctccgatt aggccgctgc
    16141 acagatcgga aataatatct ccgtacagat tctgcatgac catcacatca aactggttcg
    16201 gattcatcac cagctgcata caggtgttgt caataatctt gtcatctgcc tcaatctgag
    16261 gatactcccc ggctatctcc cggaaaatgg acaggaacat tccgtccgac ttcttcagga
    16321 tgttcgcctt gtggacgcag gtcacttttt ttcttccatg aagcgccgca tattcaaagg
    16381 cgtcgcggat aatccgctcg ctggcctttc tggtgacaat cttaacggca tgaacggtat
    16441 tttcatctat ctgctcttcc tgtcccacgt aaaggccctc tgtattttcc ctgaaaatca
    16501 caatatctac atcgtgaaac ggcgtatgga ctgcagcatt agagcggacc ggacgaatgt
    16561 tggcatataa gtcgtacatt cctctgagcg tcacgttcag ggagcggaat cccgttccta
    16621 ccggcgttgt aatgggagat tttaacagca ccttcgttct ctcaaaagag cggcaggctg
    16681 cctccggaat caggcttccg cttctcttcc attcattttc acctacgtca aacaattcgt
    16741 aatccagggg cgcgccagcc gcctccaaaa tttttaatac gctgtccact aattccgggc
    16801 cgattccgtc tccccgaaat actgtgactg tctttttcat gatctgtctc ccttctgcca
    16861 gccctccaga gccggtcttt ctttttccgt cctatttctc taccaaatct ctacaaaagt
    16921 tcagctactg ccaggttgta aacggcgcag cagatcacgc tgactggaac tgcgataaac
    16981 aacaggcggt tgaacaggtg gtttctgtcc tcctcacttc ctacagagcc taaaatcagg
    17041 ctgccgccgg aagaaaacgg gctgatggcg ctgctctggg ctccaagcac cgtgcaggca
    17101 aacagcgcgg caggatttaa gcctgtggcc gccgccagcg gaggaattaa cgggaacagg
    17161 gccggcgcta ctactcctgt ggtagaactg aagaaactca taaaagcgcc tacaaagctg
    17221 aaggccagcg gcaccatagg cgtcggtacg ttcgatccga tccaggcgga aagcgcctcg
    17281 attgttcctg cctttaccgc taccgcaatc agcattccgg ctcctgcaat cattaaaatc
    17341 gtattccatg gaatgcgggc aatcacctct ttctgaggag ccagcttcag taaaagagca
    17401 gctactgcaa agcagacggc aaccaggcct acgtcaattc ttccgctgat gacgcccacc
    17461 agagtattct gaggaagcgc cagctttaaa agcgggaata caagcacaac tgccatcatg
    17521 gccagcatca gatataaggt cagcttctga tccttctcaa acgccgccgg tttttcaaat
    17581 acaactcctt ttccaattcc gcggttggaa cggaaaccaa agcggaacac gctgataaga
    17641 atcagggaaa atacaataga aaatgcaaaa atcttcattt cctctgtaaa ggaatcaggc
    17701 gccgcaaggg ccggttccgc ctcgtaggca gtctccatca ggcctctgaa caccacgcct
    17761 aaggccgctg tggaaaagtt tccgcctgcc agagcgccgc agttaatagc caccgctccc
    17821 gtaagcttat ccatcttcgc ttcctcgcag atcagcatgg taataggagc cagaaatgcc
    17881 agtaccgtaa aatacgccgc tcccattata gaaaggacta ctgccacgaa aaataaagcg
    17941 aatggaagca ttcccggaaa tttcctgcat gtataaagca ggtgggacga cactttttcc
    18001 agggttccgt ttactgccgc aaagttataa aacagtgaaa cgcttaaaat aacaaacatg
    18061 gtgctggtag gccagcatgc aatcaattcc ttcgtagtca tcccaaggcc gaaacagcct
    18121 aaaaggtagg caaaggccat acagaaaaag cctgtgttaa tctgcgtctt atatcccaga
    18181 acgaccgcca gggcgattga agctacaagc agtatgctga gcatgattac tcctcctctc
    18241 tgattcccag aagctgtctc tggatcgtgt gggtcatata gtaaacctca tctctggaaa
    18301 ttcctccatc taacaggaac tggatatact ctgcaagagc cagctcccag tggggattct
    18361 ccgtctgtcc gccgtctgtg gacaccatca catttttata tccggcttcc ttcaccatgt
    18421 ccaggttatc ctgaagatta ctcttatatc ggccgtttcc catattttgg gcgtaacacc
    18481 gctctaaaat aatgtcataa tcctttacca tgcggatctg gtcctccagg ctcatgtcca
    18541 caatccacca ctccggatgt gtcaggacaa tctttttgat tcccgcattt ctggcctcct
    18601 ccactacgat aaaggcttcc ttgggagaaa tatgggcagt tcctaacact gcgtcgaaat
    18661 ccttcaccag ctggaaaata tctgaaagtt ccggcacgat ttttccgtct ctcaccactt
    18721 ccgcgcactg gctggcatcc tgccccacct tttccatgtg gtttctggct gactgcgtgg
    18781 gcagccatac aaccttcgct cccagtttaa gcgcagtctc cgccgctttc gggttgattc
    18841 cccctaccac gcggttcaag gtaatgcttc cgaacatggt aaagtcattg gtgcctccat
    18901 ggactctctc attgtaccgg ttgcacagat aggctctctc tgccgtactt ccctggtggg
    18961 ttttaatcac gattcctctg gctcccgccc tgatcccagc ttccatcagc tcaaaatcat
    19021 catacgctct gagccgtaaa tcgggattag aatggacgtg catatcaatc acgcctttca
    19081 tcagattgct gctcatgttt tcccttcctc tcttgtaatg cacattgtat atttttgata
    19141 ataaatccgg attgctttta gacgtttttt attatacact gagttatatc atcggagaaa
    19201 gacagatttt ttaatagaat ccatcggaaa aaacaatatc aaaacagggg gagactactc
    19261 tatggatatg aaagaactca attatattgt tgcgattgca gatgcaggaa gcatctctgc
    19321 cgccgctgaa aagctgttca tggctcagtc aagcctgagc caggctcttt ctttatatga
    19381 atcagaactg ggaacgccta tttttgtgcg cacctcccgc ggagtacgcc ccactccgtc
    19441 aggaagtgtg tttatctctc atgccaggca gattttaaat cactaccgcc tggcccagag
    19501 cgaggtctgg gatattgaag ggctgaacgg aggcagggta gaattcggca tcagttcttt
    19561 ccgcggaacc taccttcttc cccctgccct gaagcagttt cacgcctcct atccgcagat
    19621 tcaggtggaa atcacagagc tggacagctg ggatctggag gatcggattt taaaaggcct
    19681 gttggacatt gccctgattg ccgctccatc ggaaaaaatc aggcacagct gcgattttct
    19741 gatgaaggac gaaatcgtcc tggccgcgtc tgtaaaccat cctgtcatgg ccttcgccca
    19801 tccctgcggc caacactccg gcgaatactg gatcgatctg aaggacacaa aagatttcac
    19861 ctacattctc ggttctcctg gcacagttct gggaaaaatg cttcgcaggg agcttttaaa
    19921 ggccggcgta gagccggctg cagccagctc ccaggtttcc gcccccatgg ccgccgctat
    19981 ggccagagcc gggctggggc tggccgccac ctaccgctcc tgtattccgg ctcatgaatc
    20041 ggcacagtat ctgaaaatcg gcagaaaggg cgtattttta gatctggccc tgatttaccc
    20101 atctggaggc taccgttcca aagcagcagc ggctttagga gaagtactcc ggcagactta
    20161 tctgggactg gaacgtgaaa cgcggcagat atatgattaa gacctctata tttaagtaaa
    20221 aaaaggacgt tccccagctt ctcacatcaa agctggaaaa cgtccttttc tctatttctt
    20281 ttttatttta tctgactatc tgagcatcac aatgttcata cctgctgact ctgcagtctc
    20341 cttacaggct cttcactgta ttgaccacgt tctcaacagt aaatccaaac ttctcgaaca
    20401 gctctgccgc cgggccgctg gctccaaagc ccttcatgga gacgatggct ccgtcgagtc
    20461 ctgtatatct ctcccatccg aagcttccaa gggcctccac agccactctc tttctcactg
    20521 ccttcggaag tacagactct ctgtactcgg cgctctgctc ctcaaagaga tccatacaag
    20581 gcatggatac cacgcggatc ttcattccgt ccttctcaag ctctgccttt gccttcactg
    20641 ccagtcctac ctcagaacct gtggcaatca ggatgacatc cggagttccc tcgcagtcct
    20701 ccagcacata gccgcccttt aatgcctcct tactgctgcc cttcatcggc tccagattct
    20761 gtctggaaag aactaaggct gtcggagtgc tcttagatgt aacagcgctg taccatgcgg
    20821 cctgtgtctc tgtggcgtcg catggacgga acacatggaa gttcggcatt gcccgaagag
    20881 ctgccagctg ttcgataggc tcatgggtcg ggccgtcctc gcctactcca atgctgtcat
    20941 gggtaaacac ataggtaagc ggagttccca tcagcgcgga cagacgggcc ataggcttca
    21001 cataatcgct gaatacgaag aaagtagcca catatggctt taaacctccg tgaagagcca
    21061 taccatttcc gatagcggcc atagccagct ctcttacgcc gaagtgaaga tttcttccgc
    21121 ttctgtcctc tttagagaaa tctccctttc catccatata agtcttgttg gaaggcgcca
    21181 gatctgcgct tcctccgatc aggttcggaa gtctgtcttt taatacattg ataatctttc
    21241 cggaaagaga acgggtagcc tctgccttct cctgtgctgc ccagtaggaa tcatcgttta
    21301 acagatcctc agctgtaccg ttatgatact ggttccacag cttctccatc tccggatatt
    21361 cctcacagta agcggcaaac atcacattcc atgcagcttc tgcctctgcc ttctcgttag
    21421 acagctcgtc gaaatgtctg taaacctcct ccggtacgaa gaatgcctcc tcgtaaggcc
    21481 agtttaaggt ctctctgaga gccttcacat tctccactcc cagcggctcg ccgtgagcgc
    21541 ttgccttgcc ctgcttagcc gggcagccat aaccgatctc tgtcttaata gtaatgaaag
    21601 aaggacgctc tgtatcctgc ttggcagcct cgatagccat agcaatagaa tcaatgttat
    21661 tgccatcctc cacggtaatc gtctggaatc caaaggcgcg catacgctcc tccacattct
    21721 cacggaacgc aatgtctgtg cttccctcaa tggaaatgcg gttggaatcg tagagcacga
    21781 tgagcttgga aagtcccaga gttcccgcca gtgagaaagc ttcagaggaa attccctcca
    21841 tcatacagcc gtctccgccc agcacgtagg tataatgatc taccaccgga tattcttcct
    21901 tgttgaatac gctggccaga tgtgcctctg ccatagccat acctactgcc atacccattc
    21961 ctgcaccaag aggtcctgta gtggcctcca cgcctaccgt atggccgtac tccggatgtc
    22021 caggagtctt agaaccaacc tggcggaagt tcatcagatc ctcctttgtc agatctccta
    22081 ccttaaacag gtgaagaagg gaatagagaa gcatggagcc atggccgccg gacaggataa
    22141 agcggtctct gttggcccag tccggattgg acggattgta gtttaaatga tgcgcccaaa
    22201 gctcgtagcc aataggcgcg cagcccagag gaaggcccgg atggccggaa tttgccttct
    22261 ggattgcgtc ggcagctaaa attctgacag cgttgataga gagagtatca atctggttca
    22321 tttgtataac ctcctgaaaa ttaatttggt gtttgggtat atcgtttatt tcagccggat
    22381 gcttctgaca gtgtcccctc cggtgaaaat aagctcgttc tccatttttc ctgctctgac
    22441 ggcggaaaat gtgaaatcaa atgaaccgga aaacctgcat tttccagaca tattatagat
    22501 ctcacacgaa ttctcattat acagaattac catatccccg tcaatatcta tctccttata
    22561 ctggaagctt acaggctggc tgaactttaa ttttccgcct gcgctgtaga cgtccagccg
    22621 gtaatcggac tctccttccg gattttccac caccacgccc acgtatttat cggaatagca
    22681 gacgcttttg atttcttcct ccagcttaat gtgggcggaa agcgccggag aggtctgatt
    22741 ttccagagaa aagaaaccga tctgaccggt tccgaaggcg caggcccgat cctcgttcag
    22801 gaaacgcact ctcggaatca cgctgtcctt catttcctca aaaccgccta ccagacgatc
    22861 cggatagctc tttccatatt cggaaaagtt atagaacgcc accctgtttc ccatcattcc
    22921 gtcctgaaga tacacattgg acaccatcac ctgggatccc tctggagaga gagagacgtc
    22981 catcaggtat ccgctctttg acatgacggt tttaatcagc cagtccagct cgcttccatc
    23041 ctccttaaaa aaggaaatat aggaagctgt gctgtcctct aaaagcaccg ccgtcacgcc
    23101 gtgggctgag acggaagctc tcagaatcgg caacgtcgtc tccgcctgcc ctctctgccc
    23161 ttcctgattg catatgtaaa gagaattccc ctgcctgtcc gcaatgacgg cgtaggaacc
    23221 gttcacatag cagaccggcg atttcatctg gtagctgatg gaccagacaa tctttcccct
    23281 gctgtcaatg taggaagctc cgtccttcgt atactttaat acgttgcttc caaacggctc
    23341 atatccggcg aaaccattct cgctggctgg aatctgcttt tcccatacca ctcggtagct
    23401 ttcataccgg cgcacataaa gataataata ggccgccgca agcgccgcta aaatgagcgc
    23461 cgccaggatg atgaacatac gaatccgctt ctttctggtg cgggcctccg cattcctgac
    23521 aatctcttcc tcgtccagtc cgcggccgcc tccctggctc tgcccgcctg gagagctgat
    23581 cattctctgg cgaagctgtc tttttttctg ttctctgtcc atagagtcca tattactcat
    23641 ctgcttatct cccattctgt caatcctatc tccgattata caacagaatg tgggagatat
    23701 cactaaattt tttgctccca ggcggcaaac tgcaatatct ggactgccgc agtaactcct
    23761 atttttccac caaatccttc atctcctccg ctacaggcac gtctgccgga agaatcagct
    23821 tctgccccgc cgccacatgg ttcatatccg tcattccgtt gagagcgcag atatcctcca
    23881 catggttcac atttccatag agcttaaagc agattccgta cagggtttct ccatccccca
    23941 ccgcgtatgt tccgcccggc tttttgtctg tggcaggcgc ggctgcctct tttgtctcct
    24001 gagatgcagt ttctgatccc tgatgttccg atgcctgagc ttttggattt ccgtctgcct
    24061 gagtttccct gctttctgcc gacggatcct ctgtctggct ctctgtctgg ctctctgatt
    24121 tctgaaattc tgccccctgg ctctctggct ctcgaagccc gtccccgctg ttctggcttt
    24181 caggctgcgc ttctgcaggc agttccggag cagacgattc cagggctgtc tcctggctta
    24241 aatcctgttt ttcctgaatt tctgccgttt tctctggatc cggctccatt tttacaatct
    24301 cctctccctt ctctccgcct gcgctgcttc ccaccagacg gttcgattcc tcctccgttt
    24361 tcggataaat ccgcccctta atctcctcca caatcaccgg tgcgctctcc tcccgctctt
    24421 ctctgtccgg atcccagggc cttgccccct ccggaagcac agaaaccagt accgtctcca
    24481 tctcctgcat tttctggtaa ttgttcatca tggccacgcc tcccgccaga atcaccatgg
    24541 acatggtact gcacagaagt cccagatttc tgactgtatg cctctggctg accgcttcct
    24601 tttttctgtc ctccattctc tccctgaaat ccctgatcac acggtctcct gccccggatt
    24661 ccactctccg cacatctttc cggcagatca tatagtcctg catcatctga tttttatcat
    24721 aatagatgct gtagcccttc aggcggtaaa atccgtcgtc cgaggtgacg tagacagact
    24781 cctcgccctc cagaccgctg tttaagtaca tcagctggtt cttttcactg aaatactggc
    24841 catgctgttt ccagtaattc agcgggctta acgtgcatcc tggcgctccg cagagaaacc
    24901 acccctgcac cgtccgcctt ggaaacgact cctccatact ctgataggct tttttccagg
    24961 ccgcttccgt aaactcgact ttttctccct cggccgtcac atcctccatt tccagagctc
    25021 cgtctacaaa aataaagggg actccgttct ccgtccgctc tgtccccaac agcagtcccg
    25081 ctctcagatc ctgccctccg gaaggaaaca gccgctttaa atacgtgctg acgtaatcct
    25141 ctatgtacag cctgaccgtg tcgtctctgt ctcctatctg cctgatgttt ttcggcagct
    25201 ttgataatgg ctcgtataaa tctcccatat tggctcaccc cgcttatcta tttcctgctg
    25261 ccagggcctg tccggccccg gcggcttcct gcggcagccc ggtcattttc agaccgccgc
    25321 cagcttccat ccgggccatc atatcacaga gccagtaaaa aacttgtcaa atcaacgccg
    25381 cgttatccca aaatttttcg acaattctta tgcttctgct gatgcagtcc gccattctca
    25441 tcaccacaga caggcggacg ctctgaagca tcagaggatc atagctgctg catcctccca
    25501 caatcccggt aataaaaata tctcccaccg cccccagctc cttgctgacg cccaggcctg
    25561 gcctcagcgc ccccttcccc agagtcagat atcccacatg ctctctgttt cccacagagg
    25621 cgtccaccgc caccacaagg cagtcatggt aacagttttt gataatcctg gcgtactctt
    25681 ctaaattcat ggcgtgaacc gggcgttcca gcgtcccaaa tacggctgcg caggaacgct
    25741 tcatatcgcg gagcttatat ccaatcagcg gccccaggct gtccccggtg gatcggtccg
    25801 tcccgatgca gagaaatacc actccctttt tcccctgtct tgccttctcc tcctcaatca
    25861 tctgatgaag ctgtctggca aaatcctccg ccttaaaatt tctgtccgaa ttaaaataat
    25921 aaatattccg gctgtccttt gccgacatcc actctaacat tttcattccc taaccgcctg
    25981 tcgttttcat tcattgattg ccgtttctca tttccaattc tattataggc agaatgtgcc
    26041 aaaaatatgc ggacaggcag atcgaaaaag agaagcccca aaagactcct cctattttct
    26101 cttatttatt ttctgaccgc cgggccttcc ccgtttttat accgttctat ggcttcgctg
    26161 atattggagg cctcccctga ttcaatcagg cgtttcaggc catctatttt ctccacgttt
    26221 aaaaactccc gtcccaggta ggattcgtag gtgtccgtca tgtacatcct cttctcctgg
    26281 agaatggttc tgacatactt cagctgcccc actgcgtcct catattcctc tgccatgcgt
    26341 tccagctttt cccggctgtt ttccgtaatc tcgtctgaaa tgatcatccg cgtcacattt
    26401 tcaaaggaat tcaaggcgtc ctttttcttt ttcagcatgt cgtccatgtc ctgctccagc
    26461 tgggaaatct cgtcgtcaaa ccgctccaga ttgtagaggg attcattccg atcccttttt
    26521 acggaggagg tgataatgtg gattttcctg ttgttggaga gaatgacatt tcgaatctgt
    26581 ctgccctccc gaagggcctg ctggtggtgt cccctggtca tattgccaac aatcgtgtaa
    26641 agtcctccaa acacaatcac acaggcaaaa tagataagaa tcaggtacag cgtcttctgc
    26701 accggaagca gcgagtaaat cccgcacgga acagccagaa agcacaccac cagagaaatc
    26761 agaagcagca tggcctcctt aaatcccctg gtaaaataga gcgcatagta aaaaccgctc
    26821 tgacagaagg acggaacgtg ttccttctga aataaggttt tcattctgac tctcagctcc
    26881 ctgttatgaa gatgaagttc tgaagtctcc tccttgatcc gctccttaat tccctgattt
    26941 ttcgcctttt cccgccttac cctggtcttt ttcagcctgt cctgagcgcc tgcaatctcg
    27001 ctgtcatagc tcttattaat ctcttccctt ctccgcttca cagtaaggtt gatattgtcc
    27061 gccactgcct ttttctccga ttcaagggcc tttaacagtc tttcctcctc ctctttcgcc
    27121 tgctgttcct ctctttccag gtcagcaagc tccagggcaa tctgcttcgc atctgacaaa
    27181 aatcccttaa aatctgtaat tgcctgtgcc atatagttcc tcttcccttt tcctgtctct
    27241 tattttcata ctcttctcag gcgcagatcc ttctctcctt cgagtcctgg ctctactcct
    27301 cgatcacctg tatttccaga tagtcaaaat caatggattc cacaaagctg tccttggaaa
    27361 accgcgtctt gtcgtgccac ttgaaatcct cgatattcgc gtccagccag atcggctggc
    27421 ccagatcaaa ttcatagcag accttctcca tagcgtcaaa caccatagcg gtcctggaca
    27481 tggaatagtc tccattttca atgaccgtat ccctctgcat tctgttgtct ttccacaatt
    27541 tagcccaaag ccggaacatc tcccgtctcc cttctcttct atatccagcg ccgcttctgg
    27601 ctggcagcca ttttcctata ccgtctattt tcgcatgaag ccgccggttt cgcaagacat
    27661 attttaatct atatgactgt gttcacactg gcccgcttct atgatatact ttgataagca
    27721 gtttttctgc atacagaaca ggatcgccgt cgtcccggaa gccgtatgta tggtctgata
    27781 catgggcctg cctgggcgcg ccggcatgaa aggaacatag actatggcaa acgattacag
    27841 aaacagattt gttaccccag agacggcagc aaaagcggtt cgttccggag actgggtaga
    27901 ctacggcttc ggagccggct ttccggaact gatggacaag gcgctggcca aaagaaaaga
    27961 cgagcttaaa gatgtaaaaa tccgcggcgg ccttgtcatc cgccccagaa tcgaggtggt
    28021 ggagagcgat cccgaacagt ctgcattcac ctactacagc tggcatattg gagattatga
    28081 gagaaagctc caaagccgag ggctctgcca gtttattccc atgattctcc gctccctgcc
    28141 tgagctttac cgccggcata tccgggtaga cgtggccttc gtccccgtct ccaggccaga
    28201 tgaaaacggt ttctgcggtc tgggcatctc caactatgca tggagaacta tttttgagca
    28261 ggccagaacc gttattttcg aaatcaacga gcgccttccc cgccttcagg gtgtggatgg
    28321 ctcccaccgc gtccatctgt cggaggcaga ctacattgtg gagggcgagc atgaacccct
    28381 tcctgtccgt acttaccggg atccgtccgc cactgacatc gagatcgcaa agcgcgtggt
    28441 ggaggagatt cctgacgggg ccgttctctc ccttggcgta ggcggcgttc cctttacagt
    28501 ggccagtatg ctggctgaat ctgacagaaa ggatctgggc tgccatacag gcaccatcag
    28561 cgacgcattt ttagctctcc acaaggccgg aaagctgacc aacagccgca aggagattga
    28621 caccggatac tcttcctgga atctggccat gggatccgag gagctttacc agtggctgga
    28681 cgaggagccg gagctgtttc gcccggctga cgtagattac attcactctc cggagcgtat
    28741 cagccggatg aaaaacgtca tcagtattaa cggaggcgta gagctggatc tgatgggaca
    28801 ggaaaatgcc gagtcggccg gaagccgcca gctctccgga acaggcggac agctggattt
    28861 cctggaaggc gcgttccgct ccgagggcgg aaagggattt atctgtctgg cctccaccca
    28921 caagaaaaag gacggcagct taaaatccaa tattgtcccg ttcattccag gcggcagcac
    28981 agtttccgcc cctcgaacca tgattcagta cgtggccaca gagttcggcg tagccagact
    29041 ctccggtctc tccctgaaag agcgggcaga ggccatggcg tccatcgccc accctgattt
    29101 cagggaggag cttctgcggt acgcggcaga acacttcgcc taacgtccgg cgctgaaata
    29161 taattcagta tataactgca aacgagggaa tcttcctgcg gctttcacat caaagtccgg
    29221 aaaattccct cgttttagtt ttctggtttt cttttctgcg ctttttcagc ccttcgccct
    29281 tctgacagcc ggcagcctgt ctgctacagt ctctttaaaa gctcttctct ggcctcctca
    29341 tagcctggct ttccgagaag cgcaaacatg tttctcttat agctctctac gcctggctgg
    29401 ttaaatgggt ttactcctaa cagatagccg ctgattccgc aggcaaactc aaagaagtag
    29461 aacagctctc ccaggcagaa ctcattctgt tctggaatgt tgaccataag gtttggcaca
    29521 tttccatctg tatgggctaa aatagttccg ttcattgcgc tcttatttac aaagtccaca
    29581 ctctttccag ccagatagtt catgccgtct gtatctacat cctcttcctc cagaagaacc
    29641 tctgccggag agctctccac attcagaaca gtttcgaaca taattctggc tccatcctga
    29701 ataaactgtc ccatagagtg aaggtctgtg gtcagatcta ctgccgccgg gaaaatacct
    29761 ctctggtcct tgccctcgct ctcgccgtaa agctgcttcc accactcgga aacatagtga
    29821 aggctcggct catagttcgc tgcaatctct acctgttttc cttttctcag aaggatattt
    29881 ctcactgccg cataaagcag agcgccgttt tcctcataag gcagctcaag agcctttctt
    29941 cttccgttgg ctgctccctc catcagctta tcgatatctg ctccgctgac tgcaattgga
    30001 agcaggccta ctgctgtaag aacggaaaaa cgtccgccta catcgtccgg tacgacaaaa
    30061 gactcatagc cctcctcatt tgccagattc ttcagcgcgc ccttcgcacg gtctgtggtg
    30121 gcgtaaattc tcttattcgc ctcctctttt ccgtacttct cgatcagcat tttcttaaac
    30181 acacggaatg cgatagcagg ctctgtggta gttcctgact tggaaataat gttgacagag
    30241 aaatcctttc cttccagaac gtccttcaga tcctgaatat acttgctgct gatgctgttt
    30301 cctacaaagt aaatctccgg agtctttctc tttcccttag gaagaacgtt ataaaagctg
    30361 tggcttaaaa actcaattgc agctcttgct cccagatagg aaccgccgat tcccactact
    30421 aaaagcacgt cggaatcatt ctgaatcttc tcagccgcct ttttgattct ggcaaattct
    30481 tctttatcat aatcaaccgg cagatcaatc cagcctaaaa agtcatttcc tgctcctgtc
    30541 ttgccaacaa gtacgtcctt agcgcacata actgcgcttt tcatgttctc cagctcctct
    30601 gcccttacaa agggagctgc cttggaataa tcaaatgcca cttctctgcc cattttgtct
    30661 tctctccttt tcttctgtgc ctgattatac ttctacacct gtttaacctt attatagcaa
    30721 tctgttataa atttatcaac cttgttctgg cacagtctta tgattctcct atgattctgc
    30781 cgacaaatac tggcgcagca gttcccccag ggccttcatc tcctcaggct tcagattctt
    30841 cgtccattcc tcctgctgtt tggagcgttc ccggctggcc gctatctgct caaggctgtg
    30901 ctttaagtaa tcaatatccc tgattccttc tcctgacggt tcctgggcag acggcacgtt
    30961 ctgggactcc tccttcagat tttggaaaag cgcgtttttc tcctccacaa gggcagccgt
    31021 tttcttcact cttcccgttt tctcggcctt cagcctcttt aaacctgcag gcttgtccgc
    31081 ctttttcgct ctgaacagag acgctttatc ctctgcctcg cgctgtcttt ccggcatttt
    31141 aactgcttct tttattaaac cgtccctgat tgcattttca cggataatcg cttccctctc
    31201 gcttaattca tctgtatccg cttctctgac cggaagacgt ctcgcagaat cctggaaccg
    31261 ttcctgttgg cctgcattat cccggaacgc cctgacaagc acagaattat ccgtatattc
    31321 taaaagcgcg ttcgccagac gctgctgttt cagcccaatg ctgaagctgc tgtccaaaaa
    31381 agccagagcc agtcccagaa acgctcctgc cgacgcatac agcacgatat aataggaatc
    31441 cagtctgtac cagtaagcgg caaaagaagc cgcgccgcct gccataattc ctaaaattgt
    31501 catctgagca gacagattat tccagctgtt cagagaaatt ttcataaagc ggaatccata
    31561 catctgccgt tccagatagg cttccgtatt gacgatgttc tgattcagcc ggcaggcatt
    31621 ctccagcttc tgtttcaaag ccttcaaatt cctgtttttt gtcattgcca tgttgtccgt
    31681 ctcgcggatt aatcgtttgt aaaggctgcg cgtgatcaac ttgctgatcg ctccaatggc
    31741 cccgatcgct gccagcgcat ataaggcttt tcctgtttgt aacatttcca gcataaaaag
    31801 ctcccctttc ttttccagat tgttccagat ggcttttatt atagccgccc agtttatctt
    31861 tgaaaaggtg gaagggccta aaatcgatcg tcaaattccc ttataaaata agggttttct
    31921 gggatttctc ccgctgttca agccactttt tatcagtttt cctgctataa agacgaattc
    31981 cgtcgatcgt tttttccctt cagacggaac aggatgccgg cagcggccca tactaattca
    32041 tctgcttggc catctctaaa atcaggttca cagaatggcg gatcgcctgc gcctcaaatt
    32101 ctgcgtaatc cattccagcg ctgtcgtctg ctttatcaga aattgcgcgg attacaagat
    32161 atggaatgcc gtttaagtac gctgcctggg caatcgcgcc tccctccatc tctgtgcagc
    32221 ttgcgccgaa ctcttctgcc agccatttct tcttttcctt atcagaaata aactggtctc
    32281 cgctgactac gcgtccctga aaggcctgaa tgtcagaatt aactttttca ttgcaggaca
    32341 gagccagggc gcagagcttc tcgtccgctt taaatgcaaa ggtatccacc ctcggaatct
    32401 gtcccttcgg atagccgaag ccagaagcat ccacgtcgtg ctgcactgtg tctgtagaaa
    32461 tcacaatatc tccaatattg atctcatttt ttagagaacc agcaatcccc gtattaatca
    32521 cagcgtctgc ctgaaaccga tctgctaaaa tctgtgtaca cattccagca ttcactttgc
    32581 cgatcccgga tctcactacc actgcgtcct gtccgcacag ctttccaaca tagaaatcca
    32641 ttcctgctgt cctggtaacc tgcacctgcg tcatttcctc tttaattttt gcaacctctt
    32701 catccatcgc gcctataatt ccaagcatag ttctgcctcc tgtttacttt ttatttcttc
    32761 tgacattata gaagatctcc cacttcttga caattctttt tgctaaaggt tataatctgc
    32821 tagtagcgtc tttatgatgc aaaaagttta ttttattcag tatcgcttcg atatacgagg
    32881 aggaatgatt catgcttttt aaaacctgcg gcgtgtgttc cagcgccatt gaatttgacg
    32941 ttaaagataa taagataact aatgtgcatt ttatcggagg ctgctccgga aatactcagg
    33001 gcgtagctcg tctgatcgag ggaatggatg ttgatgaggc tatttcccgt atcgacggca
    33061 ttcactgcgg cgcccgcccc acttcctgcc cggatcagct ggcccgcgct ttaaaacagt
    33121 acaaagccag tctgtaacag ctgcctggct atccatttta actgctatca tataggcccg
    33181 ccagctccca ggaaacaatc tgcctgcggg ctggcgctgt ttttgtcaat ccagggaaga
    33241 ggttccaggg gttgactttt ttcttgcagc gtttactatt ataatatgtt taagaaatgc
    33301 ggttctgccg tttctcactg ttaattttat ggaggcaata ctatgaaaaa aatcattttg
    33361 accggcggcg gaactgccgg ccatgtcact ccgaatctgg ctctccttcc ttctcttcgc
    33421 aaggaagaat ttgaaattca ctatatcggc tcctacaatg gcatcgaacg gcgtctgatt
    33481 gaggatgcgg gaatcccata tgacggaatc tcctccggaa aactccgccg ttattttgac
    33541 attaaaaact tttcagatcc gcttcgtgtt ctgaagggat atggccaggc aaaacggctg
    33601 atgaagcagt accaccctga tattgttttc tcaaaaggcg gctttgtctc tgttcctgtt
    33661 gtcctggcgg caaagcatta caaaattcct gttattatcc atgagtcaga catgacgccc
    33721 ggcctggcta ataagatttg tattccagcc gcaaaaaagg tatgctgtaa ttttccagaa
    33781 accttaaact accttccaaa agacaaagcg gtactctccg gttctcctat ccgtgaagag
    33841 ctgctgacag gagatcggct ttctggtctg cagtatgcag gcctgtctgc aaaccgccct
    33901 gtcatcctgg tcattggagg aagtctcggt tccgttaccg tcaaccatgc tgtacgcagt
    33961 attctgccca agcttctttc ccagtttcag gtaatacata tctgcggaaa gggaaatctg
    34021 gatgaaagtc tgatcggcac ctcaggctat gtacagtacg aatatgtgga caaaccgctg
    34081 cgccatctgt ttgctgccgc cgatctgatt atttccagag ccggagcaaa ctctatctgt
    34141 gaaattctgg ccctcagaaa gccaaatatc ctgattcctc tctctgccgc cgccagccgc
    34201 ggagatcaga ttttaaatgc aaattccttt gcaaagcagg gattcagcac cgttctggag
    34261 gaagaggttc tcacctccga cactctgtat caggctgtct ccgacaccta caaaaagcgt
    34321 acggccttta tcgaggcaat ggaaaaaagc acgttaaaca acgcagtaga aacgattatg
    34381 aacctgatcc gggagtgtgc aaaatcataa ctccggcacg cctttttctg ctgaaacttt
    34441 aggaggagaa tcctttccgc aggattctcc ccttttcttt ccagcgtttt tgaaacgcta
    34501 ggattccagc tctgctttca gcatgctgct aatctttgcc aagtcttccg gttctgcttt
    34561 tccaggttcc catgtaacca ttgcaggtcc attttcatac cgtggaataa tgtgtacatg
    34621 aaaatgaaat accgtctgtc ctgccgcctc tccgttattc tgaactacat taaatccagc
    34681 acagcctaac gtttttttca ttgcgcttcc aatttttcca gccagaggaa gtaccttagc
    34741 cgccgtctcc tcgtctaaat gacacagatc ctgataatgc gccttaggaa gaattaacgc
    34801 atgcccctta gatgccggac caagatccaa aataacccga aaattctcat cttcataaac
    34861 tgtggacgcc ggaatctccc catttgctat cttacagaaa atacagtctt tgtctttcat
    34921 attacatttc tcctttttta ttttaagctt cttgctttgc tttttctatc tgcctgtcct
    34981 tcttgcagaa acccaggcat gaaatggtat tcccagaatg attccaatcg ccagtccgcc
    35041 tacatgggcc gcattgttca ctcccgtact ggtaaaaccc agatacagcg aaagaatcgc
    35101 cataagcacc agctgcctgc tgttcatatc tccaatccgt cctctgtttc tgtaaacaat
    35161 ccaaatcagt ccgccgatta cgccaaaaat agctcctgac gctcctgccg acatggtaaa
    35221 cggctctcct gattttaaat agaactgcag agaaatcagg tttgccccta ttccgcaaag
    35281 aatataaaac agcagatatt ttacatggcc caggcagttc tccagcttct cccctaatac
    35341 gaatagaacc agcatattgt tgagcagatg ccggatattg aaatgaagga aaatggaagt
    35401 aaacagtctg taatactctc ctccttctgt cacaagcaga ggaatcaccg ttcctttttc
    35461 aagtaaaaca tccccgctta taagaaagcc aaaaaaatcc ggaatcagaa aaagaattat
    35521 gtttatgata atcagcgcta tattgacaga tgaaattttt ttgaattgct ccatattggc
    35581 ttctatcctt ttccctcaca gacaatctta tgaaatatcc taaacgaact gcagatgcgc
    35641 gcagcatagc tgcagtttgg aattattata ccacattcac taagctcggc aaaacctcgc
    35701 taagtgtctg ggtatgactc gcactaacct catacttcgc ctgcggcttg tattcgctaa
    35761 gtgctcatat tataccacat attgactgtc tattccagat tgttcagaaa agcaaaaaaa
    35821 tatctctttt atctttatag aaattcccga aagcgataat tcagacctgc aatctgaata
    35881 ctgtctccct ccttcacgct gactgtttcg ttggcctcca gcttatatcc attcacagtc
    35941 gttccattag tggaattcat atctgtaaaa atatagacgt cctccttctg atcaattctc
    36001 aaatgaagtc tgctgactgt tgggtagtcc aaaataaagt cgttcatttc cctatgtttt
    36061 cctatcaaaa aaggaacgta tggaatctct atatcacctc tgtcttttga caagctctcc
    36121 agagctgcgc agcgtttttc tttttctgaa acgccagtta aaagctgtgt attcttatct
    36181 tcccagactg gttcttctgg agaagtatcg tcctccagag cctgaaataa aatattcagc
    36241 tcttcctgct cctttttttc cgctttttcc tgtctgacaa tgcctttcgg ctccgactct
    36301 ttacggctct ttatctccgc tttacataag tgctctgtat ttactgcggt ttcatgatct
    36361 tcctcacatt ttgaagaaat aaatttctgt actgctgtcc aaatcaaata tcctccggct
    36421 atagcaaaca ctggaagaac gccatatatt ctgattcctt cttctcccag ccaaaaatag
    36481 acggctgctt ctgccgccag aagcaggcat actattttta atgcaccaga ggattgcttt
    36541 tttctctgca gtatgctttc ttttttacct gaaatttctt ctgcagcggc ttcctcgaat
    36601 tccctgccat taagaatatc atcctcttcg tcctctgatt cttcccacct gtcgtcagat
    36661 tccccctcta aaaaggctgt tttctgttcc cgctgccatc tgtcttcatt ctgcgtcttc
    36721 tttttttctt tccactctgt ttttccgctc tcaataccag acaaatatct cagcaaatct
    36781 tccattccat aattttcttt caggctttca tggtaaagcc catatgccag cacaacactt
    36841 ctgtggtcct ggtgatccac tttttccaga atatactgca aaagacctgt aaatgcctcc
    36901 ggaaaacttc ggctgtaacc tgggagaata cagaaaaaaa tagaaaatgg ttccggctcc
    36961 acgtaaataa actccggctc cagaaggatc tgttcttcct ttaaaagaaa ttcctctatc
    37021 cggctcagca ctctggctgc tgccagcaga atttctttga tttcttcata tgaaatcaat
    37081 ctgccctcta aaagtcttga taacggctgt ttcgatgtga tctcatagta aaattctatc
    37141 cccgtctccg tgatcttctg tcgaaatttc aatagtcctt cgattgtatt accggaaagc
    37201 attctgcttt catagcattc tgtgtcatcg ctgaaagcct ctataatcat gtaattgtgg
    37261 ttcatctctc tgcggtagcc agcttttatt ttttccattt ttccctccct tcatagccgt
    37321 tctgttatat ttttaatcgt tttttgcgct cctatattcc tcccgcacgc accattctta
    37381 aaaatcgttc tggttcaaac agcttcatct gtacgtttcc tcctgttttc ccgtttctgt
    37441 gcttaaaact gcctgtcaga acagttcctc ttttgactat ttcaattttg catcctccac
    37501 atcgataata agcgctcagt gcctggtttc cccacctctc actcatctcc aatgtgtctg
    37561 tattctctcc tcctgtctgg gcctgctcca gcgcgtccat cagaatcagc attcccgtat
    37621 ttctctcatg tacataaaat ccctgagaaa tcagcgctcc acagacaaag aggacaactg
    37681 ccataacaaa ggaagcttcc acagtaatca cagcgtctgc cattttccgc cttggagaca
    37741 gctgtttttg tacttgttct cctcccgttt cccttatctc tttcataagc ttccgctcct
    37801 tttttactgc ccatatgcac gccgctctgc ttctgtcaga cggctcccat ctgaaaagca
    37861 gccaaagcga cagcggctgg aactaaaaac ggcaaaaaag gcagctggat atttttgatc
    37921 ttcttttttt caaacatccc ccatataagc atccccattc cccagaggct gcagatcagc
    37981 aggccaaaaa acaacagcgc tacattatcc caaaatccca ggtacatccc tgaaacaaga
    38041 aagaaaaatc catctccctg tcctactgcg cctttcgtaa ttttcgacag tacaagcagt
    38101 aaaattcccg ggatgagggc agctccacgc atagccagcc ataaatgtgc ctcgtacatg
    38161 tcagcccagt ctaataaaat tatataatat cctgccgtcc aggcagctgc caccgatgct
    38221 gctgcccata aaaataaaac cgaaattttt ttctctctga aatcttccca cgcacacacg
    38281 cataaaaaag ccgcaaacac cagcttcact cttttccccc tcctccgcaa tatgaacacg
    38341 cgcctaagtg cttcacctct ctcagcggaa cctctctcac atagctcact acagacgaac
    38401 agtccattct ggtgtggtag ctggaaccat taggcataat ataaacagtt cccccatttt
    38461 ccccgctgcc gcagacgctg caggcgtagt actttcctcc cgaatggctg cgaagatcct
    38521 ccactgtatc atagggcaca gccttgaaat cgtttgtaag ataatgacag attcttaatc
    38581 ggtgatatct tcccatggaa gatccaatat ataccatctc ttcaacgcct tcttcacttt
    38641 ctacttctcc ccctctgtct cctctgcttc ctatccacgc tcttctgaca gtctgggaaa
    38701 cggcaggaat tccctgaatc ctaagaatcg aaaaaggaag cttcaaactg tattctgccg
    38761 tcagcttaat gttttctccg tcttccatga gctcagcctg cgatatgact aatttttcca
    38821 gcttctcttc tcccaccaga tcagcaatct tttccctcag ataggctttc actgacagtc
    38881 ctgcaagaaa atccggcagc tggtcgatcc agtcttcctt ttgttcaagc actccctcgt
    38941 ctccctgatc caggcggtac aaaatatatc catactggct caaatctctc gcagccgttt
    39001 ccagcgccgt ctgcaccttc tgtctggttc ttagcatctc cataggcgtc atcatgcaga
    39061 tggaaaaaaa tataaataac gtaaggccaa gagccgcctc tattgtcaga gctgcatttt
    39121 gtctttttct tttccagttt ttcatattct ttttaaaggc cactctccgc acccctttcc
    39181 atactctgta cgcctggatt gtcagttttg atctgtcagc caatgtacct ggagagggct
    39241 ttttacattc agagcggaaa gaggtctgga gaatggcctt ttattatatc agtttctaat
    39301 atctgtactg ggcttttttc ctgatatcaa aggcagatcc ggatgccgta cattcggcag
    39361 ccattcccac cgaacatcgt ttcatgcgga agctcccctg gtttctgaac aggttatact
    39421 gcatcatatc cagcattctc tcatttctct gggcctgatc ctgaatcagg aaaaatcctt
    39481 ttaaatactg cccataatct aaaccggttt gtccaccaga atcatgaatt tcttcctggt
    39541 tatccacaaa tcgaaacagt tcgtccagat ccagcttcca atcgctgtct cttttcacca
    39601 gaggaacctg ttctcccttt aaaagagctc tcacatcctc cacagattct gcaaatgccc
    39661 atactcccat aataaaaaat gccacaatat ctgcaagagg cgtgacagaa gccgctccgg
    39721 taagagaagc ggccagcagc ctggcttcgt tttgcttttc actgtccccc aaaatatgaa
    39781 tcagattcaa gccttctctt actcccacca attttttcac catctgatgg agattatcgc
    39841 ggtcccgctt tttcccattt aaaagatatt cctgttcata gaaaagaccg cctttctctt
    39901 tattttcctc tttctgccct gcctgaaacc tcaaaaaatg cgctgccgca tactcgctga
    39961 tcaaagctcg atctgccagt tctcctgctc ccgtcagacg aagtcctatc tcgtagcctt
    40021 cacctcctcc agagggaaaa tccggcatat ccatggttcg aagggatggc tttgctccct
    40081 caggaagcgt taaatccaga agatcctttg acgccatttt actgatccgt tccagaatac
    40141 gcagacgttt cttatcagca attcctttct gataggaggg ggatggaatc tgacaccggt
    40201 tcaatacaga ccgtacatca tcccataatt cttcctcatc cagctcgtcg tcatcgtcgt
    40261 ccgattccca ggagtcaata tactcctgcg tttcttctgc catctctaca gcagcctcca
    40321 caatccctct gttctctgca gtctgcgcct ttatgcgttc cacctctcct ctccgctccc
    40381 cttctttatc tgtataggaa cgataggaat ccatctggct tttgataagt gtccacgcct
    40441 gttctcctat tttttctttt tgctgttccg cctcctgttc agaagcgtca agctcggctt
    40501 ccaggagcgc tgccgcctta tcatatttct ctgatagcgc cggcatccgc tccatctcac
    40561 cggccagttt ttttcctgtc ttaataaatg cccgcccctg acagttttcc agttccctct
    40621 gtccttcttc cttatatttt ttctgttttt ctaatgattc acggatatcc tccagagcct
    40681 cctccagacg gaaaacatgg tctgagctga tctggtacgc cgtttttacc gctgcaattc
    40741 catctgctga gcggatcgtc tcagccagcc cgtctaaatc catctctttt ccagcctctg
    40801 tccagattcc atacctcata taatctaaaa tttctctctc cagcggctct cctctttcat
    40861 ctgtcaccat aaccatatca gatactgcca gcttcttttt cttcattcca tataccgtat
    40921 cagaggcaag atactgatcc agatactccg atatctctct ttccagttcc tcttttctat
    40981 ctgcttccaa tagaaaaata tgatacgttt cccaggcttc cctgtgatat ttgctcatca
    41041 gagagtccag agaagaattt aatgcagtct gcagatacca gcctgagcca gccatcctgg
    41101 ctgactgaag aagcgtgcac ataagcgaaa cgatgcagat taaaatcata ctcagaaaga
    41161 ctgtcacgct ggcctgtatc tgctctgatc cagtctttct ccgcttccta actgtacacc
    41221 tcctttgact ggctgttgat ctgtttaaat atagtttcca gaagtttgtt aatctgattt
    41281 ttgaaaataa tgacaagtcc gatcaatacc accagaatca gcacgacctc gatgacgccc
    41341 actccgctct catcctcaaa aaactctctt atctccgcat tgtatcccat tccttttctc
    41401 ctttcatact tatattccaa atgccagaaa tgctggcact gacaccatca ccattacaat
    41461 taaaagcatc ataaacagtg gaattaacag cttcgttccc gtctcctctc cgatttttct
    41521 ggcagccgcc tttctctcct caaacgcatt ctccatctcc tcctccaaat ttttccggag
    41581 acttcctgaa ccgtttttca catactgtgt catcagccct gccagctttc tataggatcg
    41641 caggccgcag ctttttccaa actctccgta ggctctcagt tcagacatac cctgattcat
    41701 cctccccaca gaaatacgta tttcctcata tcccgccctt tttcttcccc ctggcagttt
    41761 caaactcatt tcatactctt tagcaagctg ttcccaggct ttcctgactg gaaaacctgc
    41821 tcccagatag acgcacaaac cagatactat atcggaataa tccaatgcca gctccgtatt
    41881 cctcttcttt ttctcttctc tttcctgaga actttccctg tattccataa gtaccgcagc
    41941 cgcagctccc agcagaagga atatatatct gtcgcagctg tgtttttcgc tgtatcgaat
    42001 ctcccgtccc tccagttttg ccggaagaat cagtttttct tcatactttt gttcttcgtc
    42061 tgcgctttct attgtatccg ccagcagttt caggctcttc tcctgctttg tcaaaacagg
    42121 ctttattact gtcacaggaa tctcatactt tctttgatag tttccggctt tcagcgtcag
    42181 aaaaagaact gtcttctcct gctccttctg catctgttcc agataaacct cccctcccgg
    42241 atcaatcagt tccggattct gcgattccca tttcatagtc atgccaaagc tatcaagcct
    42301 cgaagataat ttcagcgaac tgctcacttt gtcaaaagag ggattatctg ccaaagcttc
    42361 ttgttgtgct ttctgaaatg cctgtccaaa cttgttatca gcttcttttt tgctgtactg
    42421 ccgttcttta atctgaattt caatttcttc ttttccatcg ggaagtccct caacaatcaa
    42481 tatcccctct ttgtccccct gcccataggt atttctctca atcacgcctc caggctttaa
    42541 aaaatcagag gctcccgcca tcggatagat aagaaagaaa aacgctcccg ccgcaataca
    42601 tagaatctgt atttttctct ttttttcaaa tttcaatatc cagcatcctt cccgccagaa
    42661 tataggctcc tgcatagacc agcatacata ctgtcattac aattcttcca gccgcagtct
    42721 ggtacatggt gtcaaaaaag cccggcgacg tcagatcaat gtacaataca atcagaagag
    42781 gcagcagatt cataattttc tgttcgaact gcttctgagc tgtcataagt cttatctcct
    42841 cctgcacctg tatcttcccc cctataattt cagatacatg ggaaataatc atgccgagct
    42901 gtcctccgct ccgtctggca gccttgaaaa tctgtgcaaa gcttctgatt tcttcgattc
    42961 cgctcctttt tgcaaaatcc ccccataatt cttccagcgt cctgttcata gaaagctggc
    43021 tcctcataac agcaaactcc ttcgacatca tccccctttc accatacatc tcttccagct
    43081 gagcctgagc ctgggcaaat gagttttcca tagaatatcc tgctgccaga gaagatgaca
    43141 gcatcaggac cgactcctta aactggcgtt ttaattcctc ctgcctgcgc tgtttcaaat
    43201 ctatccgctt atacagcggg taaagaagcc ccagcggaag aaagaggaaa aaactgaaaa
    43261 aatttctgta aaacacatag gcaaacagcg cgcagaccgc cgccccctga caggaatagc
    43321 ggatccattc cctcgctgac aggcagtatg tctcatactc tgtccctcct ccttcttccc
    43381 ttccagaagc gctatggcca ggtctcccca gacatctcca gcttttgcct gttctgaaga
    43441 tctcccacct gctccaaaat gccttccaca cctccctttt ttcctccttt cgtctcctta
    43501 aactgaaaca gcggatgaag ggcaatctcc ccatcttcaa ttcccgtcac ctcctcaatt
    43561 tccagaacct ttctgctcct gtcgcgaagc cttccaagat gaataaaaat gtcaatagcc
    43621 gatgcaatct ggctgcgtat cgctgccaga ggcagatctg ctcccatcaa aaccatcgtc
    43681 tcaagcctta aaagcatgtc ccggctgctg tttgcatggc ctgtggaaat agagccggaa
    43741 tggcccgtat tcatgctttg gagcatctcc aaagcctctg ctccccgcac ctcccctacc
    43801 agaatccggt ccggccgcat tctgaggctg gctctaatca ggtccctgat tgtaatctcc
    43861 ctgcttccct cgtgattagc agcccgcgtc tccaggcgga ccagattcgg cacatgggta
    43921 atctggagtt ctgccgagtc ctcaatggta atcaatcgct cctcctcagg aataaactct
    43981 gacaaagcgt ttaaaaacgt ggtttttcca gagccagttc ctccgctgat aaacaggttg
    44041 tatccagatt tcaccaattt tttcagaaat cctgccgccg tctcagtaac gctccccagg
    44101 cttatcagac gttccattgt aataggttcc ggaaattttc ggattgtcag aaccggaccg
    44161 tccagagcca caggcggaag cactacgtga acgcgggaac cgtcctccag cctggcatcc
    44221 gcaatggggg aagccgcgtt caccgtacgg tttacacggc ttacaatctg ctgaatcaaa
    44281 tcctccagct gctctctcgt ctcaaaactt ctgttccacc ggcatatggc ccctcctttc
    44341 tccacaaata cagactgctc tccatttacc atgatttcag taatctgggg attatccacc
    44401 agttcctgga gaatatccag ctttttaaat gaattgtaca gctcctccct cagcttcact
    44461 ctctctgcca gcggaagata cagcgtttcc cctgcctgct gaatcatagc gtcgatcagc
    44521 tccgacagct cctcatcttc catctggcgc cgtccctcca gctcctgccc gagtcttctg
    44581 cgaagctctc ttttcacctc ctccagcgtc cagctgcttt tcttttttag aaaatcaagg
    44641 gattcctctt cctgtcccaa atcccaatca ctgatttgat ttttttcagc ctttttccca
    44701 gccatgtgcc gtcccttcta acactccatt tcctctctgc tgcctctcat cagttttctc
    44761 acataatccc ccagctcgct ccacaaaagc tgctcaatat aattttccct tctcccaaat
    44821 cccctgtggt acggaagctt taatttttta actttatcca gcatcccgct gtttcccgtc
    44881 ctctctgcat aggcctcaaa ttcccgtatc tttgcagatg atattccgtc ctcctttatc
    44941 ggcatataca cgatctggca gacggagaga atcggcgcag cctgatgtcc ataatttccc
    45001 acatccagaa taataatctc atagccgcag tctgccgcca gcttcctgat aagctctgcc
    45061 atctgctctg caggaatatg agccagatcc tccggataac gggcaggcgg aatatagtcc
    45121 atatttccaa tggaatgtac tattccgctt aaccgcatac agtttaaatt tctctggctg
    45181 aaatagtaca gaatatctga aaaatcactt ttatactcct cccctgtcat ggacgccagc
    45241 cctgaatagt cttccagggt aacataaagc acccgtctgt cagccgccat aagctgccca
    45301 agcgtcagcg caaatgaggt tttcagacac ctccctaccg gggaatacac tcctatcaca
    45361 gacgcagctc ttccatgctc tgccccatca ggctcatctc cggcgctgta gcaggccatc
    45421 acctccctga taatatctga actggactga tatttgtaca cagaaggata atccttatcc
    45481 ccctctttct tctctccttc tgtaagggtt atcacctgcc cgattccaag atcgcagatt
    45541 tcatccctgt ttacctggct gctgaccagc agaatctcaa tggaatgccc gcctgcatac
    45601 tgtctcagcc tctccagaga ggtaaacgcc atcactgcaa acggaatatt ttctttctgg
    45661 ttcatcacgt ctgcaaaccg cctggcataa aacagatcca gatcgtatac tgccataatt
    45721 cgtttcatcc tgcaccttcc cttatcataa ataacgtcat accggcccac aaaaacggac
    45781 ccagacagag aagggcggac gaatccatct cttctgtcct gtaggctgtc ctttcgccgg
    45841 ttcttataaa gcgctggaca taaaagagga gatattgaaa ccgttctctt accatccctc
    45901 ttctccacat cgcgcaggcc gaccagcagc cggccataac aagtgctccg gccatgacct
    45961 gaatccactc ctccctgtcc aaaaaaactg ccatgcacgc catcatttta atgtctcccg
    46021 ctcctatcat gcgaaacagg tggagaggaa acagacacaa aagaatcatc attcctctgg
    46081 ctgccgccgg ccctgcctgt gcgcctcttc ctgctgccag aaaataccca aatccggcca
    46141 gaacagccgt ctttacaagc atgttcggaa tcttccctgt tttccagtca gaaactgccg
    46201 ccgctgtcag acatgcgtgc aggatccact ttaagccaat cgtcccattc tatccctcct
    46261 ttgtcatctc tgttttcatt tttctgtttt tcaatcatct gaaacctggg gacgccgccc
    46321 cggatatagc tggaagcttc tgaaatgaat tcccagctct ctcgaactct ttaagaatgt
    46381 taaaagaact ttagaaattt tatgtacccc tattatgtca tgagcagaca aaaagtcaag
    46441 gggaaattct ctgtttttca ttgtaataat taacaaaatg gagcttctat ttttgtatac
    46501 ttttactctg tctcaaaaaa agaaactgtt tcacagaaat tttcaaatct ctgccaaaca
    46561 gtttcctctt cttttccgcc tcataccggc agaatcattt acattttccg cgttttattt
    46621 ttccccaaac acagccttat agtcagcctg gaatttctca attccctgat ctgtcagcgg
    46681 atggcgaagc atctgctcca gaatcttata cggtacggta gcgatatctg cgccagcctg
    46741 agcgcattct gtcacatgca tcgtagtgcg gatgctggcc gcgatcacct ctgtttcgat
    46801 tccatgagtc tcaaaaatat ccataatcgt ctcaatcagc tctactcccg gctgggaaat
    46861 atcatctaaa cgtcctacaa acggagacac ataggcagct cctgctctgg cggctaaaag
    46921 cgcctggttt gctgagaaga tcagggtcac attgacctta attccctcct ctgaaagcac
    46981 cttggtggcc tttaagccct ctgccgtcat agggattttt actaccatat tgggatggat
    47041 agccgcaatc tcacgcccct ctttaatcat tccctccgcg tctgtggtga gcgcgttcac
    47101 ctcgccgctg atcggtccgt ctacaatcga cgtaatctcc tggattacct gtttaaaatc
    47161 acgtccttcc ttggcaatca gagacggatt ggtggtaacg ccgcagataa tccccatatc
    47221 gttggctttt ctgatctcat ctacgttggc tgtgtcaata aaaaacttca tttctttctc
    47281 cttccgcagt cttcctgctt gttccgttcc tttaattctg aatttatgtc acagtctttc
    47341 gctccgtctg aactgcgacg aatttctagc actattctac catatttctg tttatttgca
    47401 atattaatga gatatttttc attgactggc ctatttttca gtgataaaat gattctatat
    47461 tagtttactt ttttaaacca aggaggtgcg ttccttgaca gaagcagaag aattaaagca
    47521 atgctttcac cagtgtatgc cctttttcat tgccctggga gatgaaatcc gtctgacgat
    47581 tgtagaagcc ctgacagagg ccgcctcccg gcgctgcggc ggagattatt ccatggaaaa
    47641 tttaagtctc cacgggctga atgtcaaaga aattacagaa tataccagcc tgtcccgtcc
    47701 tgcagtatcc caccacttaa aaatactgaa ggacgcgggg ctgatttctg tgagacggga
    47761 ggggacctgc aattattact atctctccat ctcccaggcc actttaagcc tgacaggcct
    47821 cgggcgcagg ctccagtcct tcctgaatat gaaagaggaa ccttaacatt ccgcttctat
    47881 tacatatatt tcctgtctgc catccatact aaggccaaca ggaggtaaat gatccatgaa
    47941 aacgaaacag acttctaaaa aacgcggcgg ctcatgtatc ttttctttaa aggaggaact
    48001 gcgccagatt atgacagaca tggactgcgc cagaaatcac tttgatcagg cggtggatcc
    48061 agttctgatc gactgttaca tctatgaaat caacgcggcc cagctgcgtt atcagtttct
    48121 tctgcgccgc atcaaaaatc aggaataatg cgcctgttcc gaccccttca ggcagaacag
    48181 gccgttccaa tcgcaggagg tatgccatga cagcctggta cacagacagc acattttacc
    48241 atatgtatcc ccttggaatg acaggggctc caaaaaataa tccatatcca tggccggagg
    48301 aagctccggc cccggtttcc atccttccgt ccgctcccat ggaagagctg ctttcgtgga
    48361 ttccccactt aaagcagatg aattttaccg cagtctacat aggtcctgta ttcgagtcct
    48421 cctcccacgg ctatgacacc agggattacc gtctcattga ccgccgtctg ggaagcaatg
    48481 cggaatttgc ggaatttgtc tctcaatgcc atgaaaacgg tatccgggtt gtaatagacg
    48541 gcgttttcaa ccacacgggg cgggaatttt tcgccttccg ggatatcagg gagcatggaa
    48601 gttcttcccc ctatatcgga tggtataagg gaatctcctt tgactggaga agcccgctgg
    48661 gggacgcctt cggctacgag gcctggcgcg gcgtctggga gcttccctgc ctgaatcttc
    48721 agaatcctca ggtaaaggag tatctgaaag atgtcatccg gttctggatc tcggagtttg
    48781 acattgacgg catccggtta gactgcgcca atgtgctgga ttttcagttt atgagagagc
    48841 tgcgccttct ggctgaggag gtgaagcctg acttctggct catgggcgag gtgatacatg
    48901 gagaatacgg gcgatgggta aacagtgaga tgcttcactc tgtgacgaat tatgaaatgc
    48961 acaaaagtat ctactctgcc cataatgatc acaattattt cgagctggct cacaatgtcc
    49021 gccgtcttca ggcgataggc tgctctctgt acaccttttt agataaccat gacgaggatc
    49081 ggatcgcgtc caaattaaag gatccaaacc atttgaaggt aatttatacc ctcctctata
    49141 cgctgccggg cattccgtct gtctactatg gcagcgaatg gggaattgag ggcaggcgca
    49201 ccgattcctg cgacgacgcc ctcaggccca gaattctgcc ttctgaagcc agaaagcagg
    49261 aagactctga gctttcctcc cacatccagc gtctggggga aatacggaaa accttcccgc
    49321 cccttcacgg cggagcttat gaggaactgc ttctcaccaa ccggcagtat gcttttttaa
    49381 gaaccgcaga ggacgggtcc agacttctta ctgccgctaa caacgattcc tgccaggcgt
    49441 cccttaccct cccatgccca gaagcaaacg gctgtgtaag agaacttctc accggccaaa
    49501 gcttccctgt atcggacgga tttctctcct tcacccttcc gcctgactcc gggtacgttt
    49561 tctgcatagg ggaaagttct tcatagaaaa aacggcaggg caaagtgagt catacaccat
    49621 aaaattcagg gggaaatgat tatgaacaaa aaaatcggca tgggattttt cggagaatta
    49681 gatctctatc tttttggaga aggacgccat taccgtcttt atgaaaaaat gggcgctcat
    49741 cctttcacat accgcagaca ggccggcata catttcgccg tctgggcgcc ccacgcagag
    49801 gaggtcagcg tagtcggcga tttcaacggc tggaatcccg gaaaaacacc tatgaagcga
    49861 atcagcggtt ccggcatttt tgaggccttt gtgcctggat taaaagaggg ggagctctat
    49921 aaatacgcca tttctacgaa gagcagttct cttctgatga aagcggatcc ctttgccttc
    49981 tacagcgaat acaggcctgg aaccgcctct gtcacagccg atatctccgg cttttcctgg
    50041 agcgattccg cctggatgga aaagcgcaga aatcaggatc ctgtaaaggc ccccatagcc
    50101 gtctatgagg tgcatctggg atcctggcgc aagacaaacc ggccggaacg cgacaactgc
    50161 ctcacttacc gggaagctgc cagggaactg gcagattatg ttaaatccat ggggtacacc
    50221 catgtggagc tgatgggcat tgcggagcat cccttcgacg gatcctgggg ataccaggtg
    50281 accggttact atgcccccac ctcccgctat ggaatgccca aggactttat gtatctggtc
    50341 aattatcttc acaaaaaagg aattggcgtg atcctggact gggttccagc ccattttcca
    50401 agggacgccc acgggctggc cgactttgac ggagaaccgc tctacgagta cgcggatccc
    50461 agaaaaggcg aacatccgga ctggggaacc aaggtatttg attacggcaa aaacgaggtg
    50521 aaaaatttcc tcatcgccaa cgctctctac tggattgaac agtatcacat tgacggtctg
    50581 cgggtggacg ccgtggcttc catgctctat ctggattacg ggcgcaggga cggagagtgg
    50641 gttcccaatc agtacggcgg caatcagaac ctggaggcgg tagaattttt caagcatctg
    50701 aacagcgttc tcaccggacg cagggacggc gttatgatga ttgcggaaga atccaccgcc
    50761 tggcccaaag taacccacca gcctgaggac ggcggactgg gctttacctt taaatggaac
    50821 atgggatgga tgcatgattt cctggaatat atgaaattag atccgattta caggaaattt
    50881 aatcacaata agatgacatt cggcctcacc tacgcttcca gcgaacactt tattctcgtc
    50941 ctctcccacg acgaggtggt gcatttaaaa tgctccatga tcaacaagat gcccggcagc
    51001 tatgaggaca agtttgccaa cctgaaagcc ggctacacct ttatgacagg ccatccggga
    51061 aaaaagctgc tctttatggg acaggatttc ggacagctcc acgaatggga cgaaaaaaag
    51121 gccctcgact ggtatctggc cgaagagccc cttcacgaaa atctgcagcg ctatgtccgc
    51181 agtcttttga cgctttacag aaaatatccc tgtctgtccc gtctagacag tgatccggag
    51241 ggatttcagt ggatcaacgc caatgacgga gaccgcagta ttttcagctt tatcagaaga
    51301 gacgagacaa aaaagaaaaa tctgctcttt atcatcaatt ttacccctgt agccagggag
    51361 cattaccggg taggcgtccc caagcggggc aatttcaccc tggtgctgga cagcggacac
    51421 ggcttctatg aaaagggcga cgacgtacat gtgtaccgct ccaaaaaagg cgaatgcgac
    51481 ggacagccgt tctccttcgc ctacccgctg ccagcctacg gcgcggcggt attccggttt
    51541 taaccattca aaaagggcag ctggttttca cagaccagcc gcccctttct ctattctccg
    51601 tcttcctcca gaaggctctg atatacgtcc ctcttgctga ttccgcggtc cttggccacc
    51661 ttcttcatgg cttccttttt atccattccc tgggacagat accgctccat atgctctgca
    51721 attgtcatct cctcaaagct ctgctgtctc tccctctcca cctggtcaaa ggattttccc
    51781 tcaatgacaa tcacgcactc tcccttgggt tcgtgatcct catagaagga cagcgcgccg
    51841 gaaaacgtgg tcctgaaggc ttcctcgtat cgtttggtca gttctctgca gacagtgatg
    51901 tttctctccc ccagcgtctt aaaaagctct gcaagagtcc tctccagccg gtgaggcgcc
    51961 tcatatacaa ggatcgttct ggtctcccgt ttcagctctt ccagaatcat ctgcctttcc
    52021 ttcttatccg gcggcagaaa cgcctcgaag cagaagcgcc tggtaggcag gcctgaaata
    52081 gtgagagccg taatgcaggc cgcaggtccc ggaagggagg tcagctccac ccccgcctca
    52141 tggcactggc gcaccagctc ctcccccgga tcggagattc caggcgtacc ggcgtccgtc
    52201 accagagcga tattgacgcc ctttttcagc tgttccacca gatacctggc tttctccacc
    52261 ttgttatatt catgatagct ggtcatgggc gtcttaatat gaaaatgatt taacagctta
    52321 atactgtgcc tggtgtcctc cgctgctatt aagtctaccc gtttcagcgt gtccagcacc
    52381 cgcagagtaa tatcgtccag atttccgatg ggggtagagc acaggtagag ctttccctgg
    52441 ccgttttttc ctccaaagga gctgtcttcc ctcttttcct gttcccagcc ggtcccctct
    52501 ctcagggctt cattccactc taacgcttcc tgttccataa gctcatgttc ttcctgtctg
    52561 cgttcctcca ctgtctctcc tccttcttac ggcttccctt tcgtctttcc ttccgctcaa
    52621 acgtcaggcc tgatatggcc tagtatccat aaatatcata aatttcatcc atgtagacgc
    52681 ccggttcccg gtatacaatc aggggctttt ccaccttgat catggatctg ccgcccttta
    52741 ccgcctcgat cagcaccatg ttggcctccc ggtctacaaa tggatgaacc agcttcatcc
    52801 gcttaggctc cagcttatgc ctggtaaaag ccgtgataat ctcaatcagc cggtgaggcc
    52861 tgtgaaccat ataaaagcgg ccgcctggtc tgagaacccg cgctccctcc cgcaccacgt
    52921 cttccagaga gcagagcacc tcatggcggg caatcgcttt cggaagctcc gggtttttca
    52981 gcccgtggct gtcgttcata taaggcggat ttgaggtcac tacgtcaaaa gaggcagcgc
    53041 cgaatatccg ccctgcttct ttaatatcgc ctgtgacaat gtctattttt tcttccagac
    53101 cgttcagacg gacgctgcgg cccgccatct cggccatctc atcctgaatc tccagacctg
    53161 taaaatggct tcccgccgtc ttggcctcca gaagaatagg gataattcct gttcccgttc
    53221 ccagatccag cgccctctcc cctggcttta ccactgcgta gcctgacaga agcaccgcgt
    53281 ccatgccaaa gcagaaggcc ttctcattct gaataatccg atagccgttc cggtgcagag
    53341 cgtcgatccg ctcaccctcc ctaagcacaa tttccctgtt ttctgcgttc aaaatcaatt
    53401 gtcctttcta tcagtggttc ctctaattat tgtccagctt ggattttccc tctctctttt
    53461 ccagcgcctc cagctgcttg agctcagcgt ctacgctgac tctttctctg cggcgtttgg
    53521 gacggaattt caggctctcc accgggtatt cccgtatctc cttctcatcc tttcccaccg
    53581 tgacaaccac cttaaccagc tgtctgagga cgctgacgct gtggacctcg cccttcaggc
    53641 catcgtctgt cgttacataa tcgccgatat tgggaagctt gctgtttaac tcttcgtagg
    53701 tttcctcctc gttcttcaga cagcacatca gccttccgca gacgccggaa attttcgtgg
    53761 ggttcagcga aagattctgc tcctttgcca tcttaatcga aaccggaatg aactcagaca
    53821 gataggtgtg gcagcacaga ggccttccgc agatgccgat tcctcccatg attttcgtct
    53881 cgtccctgac tccaatctgg cgcagctcaa ttctcgtctt aaacacagcc gccagatcct
    53941 tcaccagctc cctgaaatca attctgccgt ctgcagtaaa ataaaataac accttattat
    54001 tgtcaaaggt atattctgcg tcaatcagct tcatctggag attgtgcttt ttaatcttct
    54061 ccaggcagat tccgaaggcg tccttctcct tctccttgtt ccggcgctcc gtctcctcgt
    54121 ccgccgccgt agccatgcgg atcactggct ttaacggctg aatcaccttg gactcgtcca
    54181 cagccctgct gcccagcacc acatggccaa actcaatgcc gcgggccgtc tccacaatta
    54241 catgatcccc tgttttaatg tccatccccg ccggatcgaa aaaatagacc tttccagccg
    54301 gacggaaccg gactccaatt acatttatca taaaattaat tctccttcat ggttaagagc
    54361 atcagttcaa gcgccagctc tgtatttacg ttagccgcca gtctcgcctt cgccttgtca
    54421 atggcgttta agacagcctc cagcccctcg taggagctgt tctggcacaa tctgctgaca
    54481 gccgtgtact cctccttgaa aatcagacag ttcatgtcct ttgtcacctt gtacattaaa
    54541 atatctctgt accacagctg catgaaatcc aggcattcgt ccagaatcag gttctcctcc
    54601 tgcatctttt taatgtaatc taagagcatg gcaatgtcca tctccttcac atttttcaga
    54661 agtgttaaaa cctctctgta gaggagctta aactcctccg aggaagccag atgaatggct
    54721 tttcccagat ttcccctggc aaacgcagcg aacacatccg cctggttctc tgaaattccc
    54781 atggattccg tcaaatagct gctgatagtc tgatccttca gcggcttcag cttcagctta
    54841 atgcaccgtg acagaatagt aggcaggaag gtttcctcgt tcgtagtcat taaaataata
    54901 atggcatagg ccggcggctc ctcaatggtc tttaagagag cgttctgagc ctgtaccgtc
    54961 atcttctccg cctcgtctac cagataaatc ttataggcgc tgctgtaggg cttaatctga
    55021 atcgtatcgt tgatctgttc tctgatatcg tctacaccga tgctgttcag cttctcgtga
    55081 gtcacccaga tcacgtccgg atgatttccg cttaaaatct gcttgcagga gtggcactcc
    55141 atacatggct ctttgtcgct tctctcgcag agaagagtca tggcaaatgc tttcgccagc
    55201 gtttttcttc ccattccctg ttctccagaa aggatatagg catgggaaac cttgtggtat
    55261 tcaattgctt tctgaaaatg atccttgatc atttcgtgtc ctataatatc tttaaaacct
    55321 gccatgattt cctcctgcat gtatgtttaa catctgctcc gcgtatcact ataaactcca
    55381 aaatccagct gtgctccgca catctggcgc cgcttctcgc ggcttgagat aatttactcg
    55441 caaacgcgca ctgcgtgctt actgtctgct ggcgcagacg gtttgctcat tatcgcggct
    55501 taagattttg gagtcagcac atcaggtgaa aacaaatgct gcttttagca acgcttgttt
    55561 ttctgctcgc gtacattata acacactcta tttgatgtgg aaagtgagaa actttgctat
    55621 catccgcggg catatcttct gattgtcttt tcgattttcc cagctatgtt tttcaggcag
    55681 tctgaaagct cctgattttc atatcgttct tctgccgtaa tcccggcctg cgccagcttt
    55741 tcttctgaaa agtctgtctc gtcagccaga aaacggcggc aaagctctgt atatttaggg
    55801 tttttctgct gtttttcccg gtttacggcc cgaatcagcc gttctccgtc ctccacctca
    55861 atataaatcg gaaccgcacc gttctctcca aaataggttc gaatactctc ataagattcc
    55921 agcgttccaa tcatcatata gctgccctgg gacaggtcga tctgcccatc ctctactgtt
    55981 gcgtagctcc aggggccgta catcgtctgg tacgtgcgca tttcaatcac ccgtccctct
    56041 gacttcatgg cttccagctg ttcttccctt ataaaatggt attccacccc ctctgtttct
    56101 ccttcccgca tggggcgggt agtataaagc gtcaccgttt taagctcagg aaaatactcc
    56161 agcagctttt tatagatagt gtcttttccc gacgcgctct ttcccattac aaaaaaaatc
    56221 tttccagcag ttttacaatc tgtcacgatt ttattccttc cttaatattg acgtctttct
    56281 tccatttcag ctgtcatgtc tcatcattca tccttcacag cgtctatgct tccatccgaa
    56341 tccaggcctt ccactgttaa acccagaccg gcatttttca acagaagctc tgctgtttcc
    56401 tgagaaatca tctctccagg cacaaccgct gggactcccg gaggatagac ggtgagaaat
    56461 ccacggctta tgcagccgca ggcgtcttcc aggcgtatcc tccgcccttt tttgctcacg
    56521 gcttccgcca tactgatgcg ccgcggcacg tccctcgtcc aggtcaatgt tccctgcttt
    56581 ccactgtatt tttccgtttc ttcagacgtt ccttccgtcc cttcatttct ccccatacaa
    56641 agcgctccgg ctatctcttc atctatctta gtaagggccg ctgacagctt aaaaaggctc
    56701 tcctctgagt ccataagaga agtcatatac agaacgtatc tgtcgcagca catctccggc
    56761 tccaggtgaa aacgccgtct gactgcctct gccagggcag ttccatttat cccggccttt
    56821 tctgcctgcg ggctgattcc cacaaccagc ttggaaatat ctctgtcaaa agccccgttt
    56881 tctcccaaaa catgatcgtc cagaacccta aggcagctcc actgttttgc gtcctccatc
    56941 cagtgttcca gccgccttcc cagctgttcc agccgttttc tcccctcccc ggccatatat
    57001 tcaatacaat tgtcaatcga agccatcatc acataggacg gactggagct ctgataaatt
    57061 ctcagataaa attccagtct ttccctgtcc gtgatcccct ctttcaaatg cagaaccgcc
    57121 gtctgtgtca gagacggcag cgttttgtga acgctctgaa tcacaagatc cgcgccgcac
    57181 tgcagagcag agcggggaaa cagcctgcct gtctgtctgt tttccccctc tccctcataa
    57241 aatgcaaaat gagctccatg ggcctcgtcc acaatcaggg gaacacccct ttcatgtgca
    57301 atttctgcaa ggctttttat atcggacaca attccctcat aggtaggaga tgtcaaaaaa
    57361 actgccccta tcctgttttc cttatccgcc tccagaatcc gtctcagttc tcccggttca
    57421 attcctccct ggattccgga ttcctctatg atttcaggat aaatgtactc tgtttccatc
    57481 cggttcagca tagccgcgtg atacgctgat ttgtgggaat ttctggccat cagaagcttt
    57541 ttcccatctg aaactgcgct gctgatcgcc gcaagaattc cacaggtgct gccgttcacc
    57601 agataatagg ttcggtccac cccataaacg gccgctgcgc gttccatgga ttcctttaaa
    57661 attccctccg ggtgatgcag gttatcaaat ccgtcaatct ccgtgatatc cacagaaaac
    57721 ggatttggaa acaaagttat ccccagctcc tcctgccgct tatgtcccgg catgtggaaa
    57781 gcataaaaat cagattcccc atactccttc agcctgtcaa tcagcttcat actgcctgac
    57841 ctcccgtttc ttcctccatt tcaaaccgtt taccactcaa tttccacagc ctgtgtactg
    57901 atatcgcgga tcactcctga ttcactgtca tacgtacatg tgtgataaaa gcagtaaatt
    57961 ttatctccgc cggacaccgc aaactgcagc cggtcatttc cctggcttct tggaactgaa
    58021 tcttcaataa ttcccagttc tccattctct gtaatcgcac agatactgcc atgaatctct
    58081 ccatttttta cagaatcaat atattctccg taaatcctgt tttcatgact ggaagcatac
    58141 atggctgtca ccacgccctg aaacagcctt cctaccttct cctgagccat attttccaga
    58201 tttacccggt aaatctgact gtactgcact ccgccgatct gctccataca tgcgctgtag
    58261 taaagccatg aacctgacag gcacaaactg tccgtgcgga ttccgttctg cggcatcagg
    58321 cctgtaaagc tgtcgtcctg agagtttcga tagatttttc tctggccgtc tggatcatcc
    58381 agatagtaga ccgttccttc atggacaata tcggcctgcc gcacgtttgc cacccgattt
    58441 ccagacatag aatagattct gtctccaaag cggatttctc cattctcgtc tgggaccgca
    58501 ggctctccct cctcatccgt gaaaacgatc gatccatcct ctatggaaac ctgaaactct
    58561 ccattttcct gatagtcaga ctcccccttc gacacgcttc tcacatcgtc tccatccata
    58621 taaaatactg tatctccgaa ggcaaaatac tctccgtcag cctcagccat cttctccttc
    58681 cgaaggccgt ccatactctt tctaaaaaca gaattcccac ttttataata aatccagtcc
    58741 ttagaaaact gcagtccttc tttttttaat agcaggctgt ccgtgatcag ctcctcctcg
    58801 ctgtctccgt ccagctcaga gcgaaaagcc gtcattttaa tctgatccga attgggaatc
    58861 tgatagctgc acacatacca cagactctga catctgcagt ccatccaaac gatgtggcca
    58921 tttccaacca cacaattttc ccgcccgctt ctgccttcct ggatgtaaat attgccgttc
    58981 ttaataaaat actgatcctc tccattgaaa gccgaaggat tctgactgtc cgcctgactg
    59041 tttttctcta ttttctccag cgcgccatcc tctgcaaacg agagaatctg ctttccatgg
    59101 cagatttttt cccggcgcaa aggcccgtct gctgtcatca aaaataaccg gccgtccttc
    59161 tgttcaaaaa acgcgctcct gagaagctcc tcctgttcct cctctttatc cttctcccgc
    59221 ctttcagagt aaacatcctt ccagccgtca tcctgctgca tctgcgccgc agtctgctct
    59281 gccttccggg ctgatattac ccctatcaca tttctgcaga gaaaaatcaa aattcctcct
    59341 accagcgcca cagtaaaaac gactcttata aagcccttaa cgtacgcctc cagaccggat
    59401 gacgacgtat cctcatcgtc aaaaacaccg tccccgtctt ctcccgacca tcccagacgt
    59461 ttctctatct gaagccacag ttctgcagcc tggctctctc caatctgttc cccttttgga
    59521 atgccctcct cctctgactc cggagctgag ccggcaagat gaaacaccat ctcccgcaca
    59581 tagcgcctga tattctcgtc tgattcagga agcatttcct tttgttcaaa taactccaga
    59641 taaaatttaa tcagcagttc ctcagactgt tcttttctca ctgctgcgca ggcagcctga
    59701 aagacttcct ccacagtcag aatatagaga tcctcatatt cgtcctggat tccatttctc
    59761 acctgccccg ctgttttctc cagcactgtc tgcttcctca tattcccctc ctgacaagct
    59821 ccctcttctg tctttatttt acggtaaaac ggcccttttt tccactgttt tttcctcgtg
    59881 ccctttgtgc tgttctctgc aaaataaaaa aacagctctg aatacaggat cacttcctgt
    59941 tttcaaagct gcttttcatt tatccctctg cttcttttta tctgagaact aaatctccat
    60001 ccttggccac ataatttctc gcaacgccca tccgctccat ccaggatctt gttttcatgg
    60061 tcttatagga acctgcgcct gccactccgt ccttcatatt atcccagagc catgccggag
    60121 tcggccagaa acaaatttcc ggatgaagca cctggtacag attttcttct gctccatcct
    60181 gtccatgatg agccatctga acgacgtctg acttcaaatc cttataatcc cacatccgga
    60241 tcagtcttgt tccaggctcc catcccatat ctcctaaaaa catcagccgt tttccattga
    60301 tatcaatccg ataggcgatg gagctgttgt taaaggtgtt gtaatctgta taaagcggtt
    60361 cgttcatcac tgtaatctca gcattatcta ccgttatttt ctgccctctt atcagctgca
    60421 tatgcagctt ttccgctgga aacctggaaa acactgccat cagattatca taatcagaca
    60481 tccgtcccat atgatctccc ttttcatact gttctctcgt taaaaaggaa cagtaaatct
    60541 gatcgatctg cacaggaatc ggatttctat tcaaaatatt ggtcagcgca cccacgtgat
    60601 cgctgtgagg atgtgtaatc agccaggctg atactctgcc tcccatcgcc tgaatcgtct
    60661 caaccagatg atccgcgtcc tgatcaagcc ctccgtcaat tacaatcact tctccctgat
    60721 tagtctgcag taaaaacgac atattctggc catctgtctg cggagccagc atcgtaagcg
    60781 acgcgcctcc cagataagta tcggcagctg aatcctgccc ctgacttcca gtcccaagct
    60841 gccgggactg cgctgaaatt tctgccggtg ctttcgcccc atcctctgcc ggagaggcca
    60901 tcactctttg aactggagct gtaccgaaaa tcatacatgc cgcagccagg gctgccaaaa
    60961 atctctttcc cttatatctt atactcatcc ttattttcct catctttctt agtctaactt
    61021 agtatagctc agtatagctg tattgttcct ctgtatcgct atacctgcgc tcagagatgc
    61081 ttcccatcct gcttttatta tgaacattca ctcgtaatta tatcagctgg tttgagataa
    61141 aacaacttaa caaattcttt caatttttag atatttttag atccttttct tcgaatcaaa
    61201 aatcaagtat gtccaggatt tcccctgtaa accggcaaac aaaaaaaccg gctttccttt
    61261 attttcaagg aaaaccggct ttcataaaat aactgaggca tcggggattc gaaccccgga
    61321 caacttgatt aaaagtcaag tgctctaccg actgagctaa taccccgtaa aaaggcaaaa
    61381 aataaatgcc cagagccgga atcgaaccag cgacacgagg attttcagtc ctctgctcta
    61441 ccaactgagc tatctgggca tttcttttat gaatctttcc atcagctgaa agcgaaatga
    61501 aaaaagacat aaaaaaattg cgggggcagg atttgaacct acgaccttcg ggttatgagc
    61561 ccgacgagct tccagactgc tccaccccgc gtcaatattt acatttctat tatatacaat
    61621 aagtatcaaa atatcaatac ttattttaaa tggatggagg tggattcgaa ccaccgaagc
    61681 gtgtcgcaac agatttacag tctgccccct ttggccactc gggaacccat ccatatgaaa
    61741 ttggctttca cctaagccga tgatcggact cgaaccgata acctgctgat tacaaatcag
    61801 ctgctctgcc aattgagcca catcggcaaa tgaaatgggg cctatagggc tcgaacctat
    61861 gaccctctgc ttgtaaggca gatgctctcc cagctgagct aagacccctc atttcaattt
    61921 ttagcttgtc gctaaagcga cccggatggg actcgaaccc acgacctccg ccgtgacagg
    61981 gcggcgctct aaccaactga gccaccgggc cattttaagg atatacatac cctcaaaacc
    62041 acacattgaa ttctactttc tatctctcca tcctcttctc tctacccaac ctcttggtta
    62101 agccctcgac cgattagtaa cagtcag
//
LOCUS       DBMDUW010000010        60693 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_526_length_60693_cov_5.545534, whole genome shotgun sequence.
ACCESSION   DBMDUW010000010 DBMDUW010000000
VERSION     DBMDUW010000010.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 60693)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 60693)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60693
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_526_length_60693_cov_5.545534"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(826..1530)
                     /locus_tag="ACZPCR_03565"
     CDS             complement(826..1530)
                     /locus_tag="ACZPCR_03565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HIR1229990.1"
                     /translation="MQNWLAIAAAVYLAAMILMGHYKGFIRMAVSAASLIVTLIAVNA
                     VMPQVTSYLKQHTEIYQTIENAIGEAIGMDESADADTPAAQRQKIEGLKLPERLKEGL
                     VANNNHEVYRLLGAETFSRYVTGYLVNNMVNLTVYLLLFGVLFGTLQIISRCLDIVAR
                     LPVIYGVNKLAGAALGAAEGLVFLWLFCLLVTAFSAAEWGAELGRLIEESSWLSYLYE
                     HNLLVTLAASLMKGFL"
     gene            complement(1584..2411)
                     /locus_tag="ACZPCR_03570"
     CDS             complement(1584..2411)
                     /locus_tag="ACZPCR_03570"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HIR1229991.1"
                     /translation="MDIKLIALDLDGTLLTEDKQLSERNRRALEACIEKGIYIVPCTG
                     RTFEGIPAAVRQVKGIQYAILTNGAQIQNAATGEVIERRALDWQRAVQIIDKISGCTL
                     MYDAYADGRGKADRRFLDTLEYYEIRPEICELIRRTREPLPSLRDYLNETHPALDKMN
                     IYFKGYDRETKRQVREALSELEGIAVTSSMPSNLEINGEGASKGNAILLLARYLGLSP
                     SQTMAFGDGENDLSMMELAGIGVAMDNGNPALKKKADFIARSNEEDGVARVIEKLIL"
     gene            complement(2565..4790)
                     /locus_tag="ACZPCR_03575"
     CDS             complement(2565..4790)
                     /locus_tag="ACZPCR_03575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003509964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIR1229992.1"
                     /translation="MDKYEFNIKVEQIKKLVNKGDYETAMKIADGIDWRRVRSTSLLA
                     SISQVYERNEEYQEAKDILLLAFERAPIGKGLLFKLTDLALREGNVSEAEAYYREFCE
                     LCGEDPRQNLLRYLILEAKQAPLEQLIVSLERYCQDELDEKWLYKLAELYQKAGREED
                     CVRICDKLMLLFGLGKYVDKAMALKQKYAPLTKYQMDLVENREKYEEKLRAVEEEYSS
                     GRRHREDEEIEADEDFDEPDDDSEAEEARRMAVGASLGEEQAEKELAREISRIPQEEY
                     HADDEEDSLGETRVLTDIRRVGREPEEGKAEALKQTAAASDSRTAGSAQAGAEEDRTS
                     ESETARREEAIARAYEEEEETVIEDWDLEPVENDSNHLMIEAEDPESGLSLALESLKK
                     IHRELGTKNPVAKISAQNLNRRGIFSVADRLSGRDLIVERAADLDEFSVRDLSELMEA
                     DKSGMIVVLIDTPSRMERLHNENPDLADKFQYIGCRAQEKAEDPEEQEIKRRQAAAAA
                     EAARRQAEYEAEQERKRLEEAAAAEENRRREEAEAARRREEERRLEAARLQAEREAEA
                     ERQRRIEEEERAKEQEFQDDYKEPAEEDYDARDFYEEDFQDDGARGREREEHDSYQED
                     EYQDEEAYEDSWDNEEQESDGYSEEGDDREMDVEEFAQYACKYASEIDCSISGKSMLA
                     LYERAEMMEEDGVPLTRESAEELIEEAADRAEKPSFGGFFSSKYDKDGLLILKEKHFF
                     D"
     gene            complement(4861..5460)
                     /gene="recR"
                     /locus_tag="ACZPCR_03580"
     CDS             complement(4861..5460)
                     /gene="recR"
                     /locus_tag="ACZPCR_03580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007707929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HIR1229993.1"
                     /translation="MDYYSSQITKLIEELSKLPGIGNKSAQRLAFHIINMPEEQVERL
                     SSAITSAKKNVRYCRECFTLTDKELCPICESQKRDHSVIMVVENTRDLAAYEKTGKYD
                     GVYHVLHGAISPMLGIGPGDIRLKELMARLQREEVKEVIIATNSSLEGETTAMYISKL
                     IKPTGIKVTRIASGVPVGGDLEYIDEVTLLRALEGRTEL"
     gene            complement(5462..5827)
                     /locus_tag="ACZPCR_03585"
     CDS             complement(5462..5827)
                     /locus_tag="ACZPCR_03585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007707933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HIR1229994.1"
                     /translation="MAKRGGFPGGMPGNMTNLMKQAQRMQRQMEETTKELEEKEYTAS
                     SGGGAVTVTVSGKKEVVSVKLSEEVVDPDDIEMLEDLIVAATNEAFRQMEDASAQAMA
                     KLTGGLGGLGGGLGGGFPF"
     gene            complement(5886..7505)
                     /gene="dnaX"
                     /locus_tag="ACZPCR_03590"
     CDS             complement(5886..7505)
                     /gene="dnaX"
                     /locus_tag="ACZPCR_03590"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007870396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HIR1229995.1"
                     /translation="MSYTALYRKWRPASFEDVKGQDHIVKTLKNQVESGRIGHAYLFC
                     GTRGTGKTSIAKIFARAVNCEHPKDGSPCNECETCKRIKEGASLNVVEIDAASNNGVE
                     NIREIREQVQYPPTEGKYRVYIIDEVHMLSIGAFNALLKTLEEPPSYVIFILATTEVH
                     KIPITILSRCQRYDFKRISLDTIAGRLKELTEAEHIEAEERALRYVAKAADGSMRDAL
                     SLLDQCAAFHFGESLTYDNVLEVLGAVDNSVFSQLFRAAVEGRAKDCISAIEEIVIQG
                     RELSQFVTDFIWYLRNLLIVQSADDAENILDTSMENLRQLKEEAALTDGNTLMRYIRI
                     FSELSGQMRYASQKRVLLEIAFIKLTKPSMEQNLDSVLQRISELEARIAQIPSPAELA
                     ALAAAGQASAAQGTAGGVSISEAAGEHTAEPETVVLPKAQYEDLMAVKGDWGKLSRKL
                     GGAMRVALQGTSLKPAGEGCLSIEFTDVNNYSIMNQENRLAELKELVEADYHRTIEFK
                     AHLRETSVPVSTVYVSDEDLKVIHDVIEIED"
     gene            complement(7525..8607)
                     /locus_tag="ACZPCR_03595"
     CDS             complement(7525..8607)
                     /locus_tag="ACZPCR_03595"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002565848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003872 - 6-phosphofructokinase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HIR1229996.1"
                     /translation="MKRIGMLTSGGDCQSLNATMRGVAKALYKKYNDEVEIVGFEDGY
                     KGLMYADYHIMKPSDFSGILTLGGTILGTSRQPFKLMRTPDENGLDKVASMKHTYYKL
                     KLECLVVLGGNGSQKTANLLREEGLNVIHLPKTIDNDLWGTDMTFGFDSAVTVATNAI
                     DCIHTTAASHGRVFIVEIMGHKVGWLTLYAGIAGGADIILLPEIPYDIDVVVDAIKKR
                     TKAGKNFTILAVAEGAISKEDAALTKKELKEKKKSSPVYPSVAYELGAKITERTGQEV
                     RVTVPGHMQRGGEPTPCDRVLSTRLGASAAGLIMRGEYGYMVSIKNNEIVNVPLSEAA
                     GKLKMVDPSCDMIRDAKAIGISFGDE"
     gene            complement(8902..9163)
                     /gene="ffs"
                     /locus_tag="ACZPCR_03600"
     ncRNA           complement(8902..9163)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACZPCR_03600"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            9359..9982
                     /locus_tag="ACZPCR_03605"
     CDS             9359..9982
                     /locus_tag="ACZPCR_03605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013279768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HIR1229997.1"
                     /translation="MNDKTMFNLTYGLFVLTASLDGKDNGCIINTAGQVTAVPNRISI
                     AVNKSNFTHDMILASGKFNVSILSEEADFSIFKRFGFQSGRDVNKFDGYEHAVRGENG
                     IYYVTEGTNGFISAQVETTLDLGTHTLFIAGVTDMDVLSDIPSTTYTYYQNHIKPKPL
                     PKTESEKGVTIWRCRICGYEYKGDVLPDDFICPICKHPASDFEKITG"
     gene            complement(10171..10680)
                     /gene="tadA"
                     /locus_tag="ACZPCR_03610"
     CDS             complement(10171..10680)
                     /gene="tadA"
                     /locus_tag="ACZPCR_03610"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008706930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HIR1229998.1"
                     /translation="MKKLTEEERCMREAVRQAKKAWKLGEVPIGCVIVYEGKIIGRGY
                     NRRTTDGNVLAHAEIIAIRKACRAMGDWRLEGCTMYVTLEPCPMCAGAIVQARIPKVV
                     IGCMNPKAGCAGSVLDLLHEDGFNHQVETEVGMLGEECSQMLKDFFRELREKKKERKK
                     EQQNEQEQE"
     gene            11017..11709
                     /locus_tag="ACZPCR_03615"
     CDS             11017..11709
                     /locus_tag="ACZPCR_03615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002577113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0051353 - positive regulation of
                     oxidoreductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HIR1229999.1"
                     /translation="MNICGLQKTTLLDYPGRVASTIFLGSCNFRCPFCHNSDLLDGCA
                     EHPFSVPDVLAFLKKRSNVLEGVCITGGEPTLHPELEDFIRKIRSLGLAVKLDTNGFR
                     PEVLKRLCEQSLIDYAAMDIKAGRANYGRACGVPGISLAPIEESVAFLLSGAVPFEFR
                     TTVVRELHSEEDFIDIAQWINGCSSYFLQSYQDSENVLTPGFSACSKEELLHYLDIVR
                     PCAKTVKLRGVD"
     gene            complement(11725..12081)
                     /locus_tag="ACZPCR_03620"
                     /pseudo
     CDS             complement(11725..12081)
                     /locus_tag="ACZPCR_03620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006773469.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6128 domain-containing protein"
     gene            complement(13482..13567)
                     /locus_tag="ACZPCR_03625"
     tRNA            complement(13482..13567)
                     /locus_tag="ACZPCR_03625"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13531..13533),aa:Leu,seq:taa)
     gene            complement(13618..13699)
                     /locus_tag="ACZPCR_03630"
     tRNA            complement(13618..13699)
                     /locus_tag="ACZPCR_03630"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13663..13665),aa:Tyr,seq:gta)
     gene            complement(13793..15922)
                     /locus_tag="ACZPCR_03635"
     CDS             complement(13793..15922)
                     /locus_tag="ACZPCR_03635"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HIR1230000.1"
                     /translation="MSVIDREALFCDETKDYRNPYEPDAGDTVCLRLRTARDNADSVF
                     YIEPETKIRRRMKRICTEGCFDYYEICVEIDEEPVSYYFEIRLGSEICFYNRLGAENQ
                     AEAAYAFRIIPGFHVPEWVQGAVMYQIYVDRFRNGDPTNDVETNEYIYIGSPVQRVED
                     WDELPGTLDVGRFYGGDLQGVWDKLDYLKSLGVECIYLNPVFVSPSNHKYDCQDYEHI
                     DPHYGVIEEDMDLLVASDAMDNDMAGKYAARTADEANLKASDEFFAAFIVAAHQKGIR
                     VIIDGVFNHCGSFNKWMDAELIYQHEGNYEPGAYVSADSPYRSYFKFNNQDGWPFNDS
                     YDGWWGFSTLPKLNYEESEELCQAVMRVAEKWVSPPFGADGWRLDVAADLGRSSEFNH
                     RFWQRFRDAVKKANPQAVILAEHYGDPSPWLDGSQWDTVMNYDAFMEPVSWFLTGMEK
                     HSDEFNEKLLGNGTTFFDIMRYHMCRMQPQSVYSAMNELSNHDHSRFMTRTNRRTGRL
                     DSAGSEAASEGISYGTFRQGVVMLMTWPGAPTLYYGDETGLCGWTDPDCRRTYPWGRE
                     DQELIEFHRYMTRIHRRHPAFCTGSVKRLLAEQDLIAYARVSEGWTAGKAELENGEMK
                     RQRESRGVTIVNTSEEERAVRIPVWLAGITDSMELRRCMLTYEEGYNAGQVLYPVKDG
                     VLEITLPPRGAAVLTAERKIQPDFRLK"
     gene            complement(16309..18156)
                     /gene="ftsH"
                     /locus_tag="ACZPCR_03640"
     CDS             complement(16309..18156)
                     /gene="ftsH"
                     /locus_tag="ACZPCR_03640"
                     /inference="COORDINATES: protein motif:HMM:TIGR01241.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HIR1230001.1"
                     /translation="MKQRQPMGGGFFLLVLALTMLVVMWMRSPNNPLTAPAMTEQDVY
                     VALENGTITKARIRPDAENSTGKLQLWLKSGDMEEVHVLNVSDFAEEFRDDGIPYEVE
                     EIPKENYALTIMLPILLSAGLLAAFFMFMNLRNAGGGNAKMMNFGRSRARMSRDSKVT
                     FANVAGLSEEKEELEEIVDFLKDPQKYTGVGARIPKGVILVGPPGTGKTLLAKAVAGE
                     AKVPFFSISGSDFVEMYVGVGASRVRDMFEEAKKNAPCIVFIDEIDAVARQRGTGMGG
                     GHDEREQTLNQLLVEMDGFGVNEGIIVMAATNRVDILDPAILRPGRFDRKVVVGRPDV
                     KGREEILAVHTRMKPLGEDVDLHRVAQTTSGFTGADLENLMNEAAIHAAREGRKYLMQ
                     SDIDRAFIKVGIGTEKKSRVMSEKDRKITAFHETGHAILFHVLPDVGPVHTVSIIPTG
                     TGAGGYTMPLPESDEQYITKGRMLQQIMVSLGGRIAEELAFDDITAGASQDIRQATAI
                     ARAMVTEYGMSERIGMIDYGSNENEVFIGRDLAHARTYGEDVAAAIDQEIKRIIDECY
                     QKAKEIILSHKEVLSQCSQLLLEREKIGQAEFEELFNRIENGTDGQTEN"
     gene            complement(18169..18693)
                     /gene="hpt"
                     /locus_tag="ACZPCR_03645"
     CDS             complement(18169..18693)
                     /gene="hpt"
                     /locus_tag="ACZPCR_03645"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HIR1230002.1"
                     /translation="MADNIRVLLTEEEVNKRISEVAAQINKDYEGRPVHLICILKGGV
                     FFTCELAKRLDLSVSLDFMSVSSYGSGTESSGIVKIVKDLDEPLEGKDVIIVEDIIDS
                     GRTLAYLIEVLKQRNPKSIELCTLLDKPERRVKKQVQVKYTCFTIPDEFVVGYGLDYD
                     QKYRNLPYIGVVEV"
     gene            complement(18686..20131)
                     /gene="tilS"
                     /locus_tag="ACZPCR_03650"
     CDS             complement(18686..20131)
                     /gene="tilS"
                     /locus_tag="ACZPCR_03650"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HIR1230003.1"
                     /translation="MSLKEKVLSYIRTHNMLAPGQRVVAGLSGGADSVCLLSLLADLR
                     EEYSLELRAVHVHHGLRGEEADRDAAFSRELCRSLGVPFSLAFVNVKEEAGKRRISEE
                     EAGRILRYQVFEREAGRWEQELRREKTAEPAGSQPESVKIAVAHHGDDSAETILYQLF
                     RGSGLKGLSGIPPARGNIIRPLLCAERREIIAYLEEKGLPFVTDSTNLENDYARNKIR
                     NQILPMAVQEINQGAADHIRRAGELIGEADRFFEERAERMLETLLETEALETGETKEQ
                     GSESAALSVSGLLELSHIEASYAVRAVFKRKKWPLRDVTSGHIESVLALLRGRTGAGS
                     DLPGGLRAERSYDRLILAKLQPGQTEKRDESGLPSLFMEVADRENQGEIPKNLYTKWF
                     DYDKIKDTLSVRYRLPGDYITLKGGGRKSLKSLFIDEKIPREERSHIPLLAEGSHVLW
                     VIGGRISEYYKVTEETERILKVQVDGGINCG"
     gene            complement(20169..21578)
                     /locus_tag="ACZPCR_03655"
     CDS             complement(20169..21578)
                     /locus_tag="ACZPCR_03655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007871097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="HIR1230004.1"
                     /translation="MIGKKLHRDMAEVNVYTARRLREMACSLSGLARAFTEEAGSDKR
                     LSFDEGLAAMQTAASMVCGGCSRCNLYETGKKEGSYYLYYLLRAFEQKGKVDKEDMPR
                     LFHESCRRQEEYLSQLNRNLGRATMNLTWKNRFLESRDAVIVQFREMASILEEFSGQM
                     ERALDVTETYEDSVRYLFRRRHMKVENMLMLEYENDQKEAYLTMRTVGGKCVTSRDAS
                     DILSRAAGGRRWSVSRDTKSIVTRRTDTFRFVEEGKYQMIHGVARAVRGGEVTSGDSF
                     TFSEGLPRQMIMSLSDGMGSGAAALADSARVVELTEQLLETGFSARAALKLVNTVLLL
                     AGMEQNPATLDLCCVDLCTGVLESMKLGAVGTFLMGREGVEMIEPGSVPMGVMNPVEP
                     ALVSRKLWDNDRVIMVSDGVLEALPGEEKEETFRQYLEELEPGNPQDMADEILSFAMS
                     FSEQPADDMTVLVGGIFEK"
     gene            complement(21683..22003)
                     /locus_tag="ACZPCR_03660"
     CDS             complement(21683..22003)
                     /locus_tag="ACZPCR_03660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007036002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HIR1230005.1"
                     /translation="MRRQDRTAGKKKKEKAANRLALMGITLVVLSLAVTVHLSGISME
                     EKDLQYRLKEEQLEKQKSEEEQRAQELEEYRIYVQTKEYIEKVAKEKLGLVNKDEILL
                     KPEK"
     gene            complement(22027..22353)
                     /gene="yabQ"
                     /locus_tag="ACZPCR_03665"
     CDS             complement(22027..22353)
                     /gene="yabQ"
                     /locus_tag="ACZPCR_03665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0034301 - endospore formation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex biosynthesis protein YabQ"
                     /protein_id="HIR1230006.1"
                     /translation="MDTIYTEWSCMAAALTAGMTLMLVYDGLRLFRLFVSHAPIWTGL
                     EDLLYWIGAGLSVFFLLRSRNEGEMRVYMIASVLIGMVFYDKTASHLLFTLLKKLKKY
                     FKMKRK"
     gene            complement(22364..22648)
                     /gene="yabP"
                     /locus_tag="ACZPCR_03670"
     CDS             complement(22364..22648)
                     /gene="yabP"
                     /locus_tag="ACZPCR_03670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030435 - sporulation resulting in
                     formation of a cellular spore [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YabP"
                     /protein_id="HIR1230007.1"
                     /translation="MEEKISRRPHHLDLMNRGTGSVTGIQDVVAFDENQIVLDTDMGL
                     LTVKGKGLHVSRLTLEKGEVDIEGTVDSLVYSSNETYRKQGESLFARLFK"
     gene            complement(22711..22950)
                     /locus_tag="ACZPCR_03675"
     CDS             complement(22711..22950)
                     /locus_tag="ACZPCR_03675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002605178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HIR1230008.1"
                     /translation="MRLDKFLKVSRLIKRRTVANEACDAGRVLVGGKPVKASYAVKTG
                     DIIEIQFGVKSVKVEVLDVAETVRKDDAKELYRYL"
     gene            complement(22955..23257)
                     /locus_tag="ACZPCR_03680"
     CDS             complement(22955..23257)
                     /locus_tag="ACZPCR_03680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013274629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030527 - structural constituent of
                     chromatin [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIR1230009.1"
                     /translation="MRRSRRNKSMNKTELIAAVAEKAEISKKDAEKAIKAFTEAVSEE
                     LVKGGKIQLVGFGTFEVSERAAREGRNPKTGETMPIAASKTPKFKAGKALKDMVNA"
     gene            complement(23366..23821)
                     /locus_tag="ACZPCR_03685"
     CDS             complement(23366..23821)
                     /locus_tag="ACZPCR_03685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG nucleotide pyrophosphohydrolase
                     domain-containing protein"
                     /protein_id="HIR1230010.1"
                     /translation="MNGKETENIQSLKQFYGADRPDAYTLEDLRNILRILRSDEGCPW
                     DRKQTFETMVSCVLEEAGEVTEAVRNQDTENLCEELGDLLFQVVFYCQMAEEQGLFAF
                     EDAVDGISRKMVRRHPKIFGGDLPETDGNEGDLWERIKRAEKAKNHKTT"
     gene            24188..24450
                     /locus_tag="ACZPCR_03690"
                     /pseudo
     CDS             24188..24450
                     /locus_tag="ACZPCR_03690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009266637.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
     gene            24541..25089
                     /gene="spoVT"
                     /locus_tag="ACZPCR_03695"
     CDS             24541..25089
                     /gene="spoVT"
                     /locus_tag="ACZPCR_03695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HIR1230011.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRRTLRLREGTPLEIFTDREGEI
                     ILKKYSPMMELTAFSSQYAEAMAQSTGLMVCITDRDQVIAVSGGPRKDYLQKSISRQL
                     EGLIGERQIVTAGKDDRGFIPLTPDEPEGATAQVIVPIICEGDAIGSVILISREPRVK
                     FSETELKLASTAAGFLGRQMEG"
     gene            complement(25169..26467)
                     /locus_tag="ACZPCR_03700"
     CDS             complement(25169..26467)
                     /locus_tag="ACZPCR_03700"
                     /EC_number="4.4.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0080146 - L-cysteine desulfhydrase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-cysteine desulfidase family protein"
                     /protein_id="HIR1230012.1"
                     /translation="MERTDSRYQAYMNILKEELIPAMGCTEPIALAYGAAVARQELGA
                     LPDRVVVGVSGSILKNVKSVIVPNTGHMKGIAAAAAAGIVAGDAKKELEVISQVSEEQ
                     IKEIREFLDRTDIRVEHIDNGLMFEILITMYKGEDWSRVRIANYHTNVVLIEKNGVVK
                     KEVKVEGESEKGLTDRSCLSMEGIWDFINTADLDDLKQVLKRQASYNMAIAKEGMTHS
                     YGANVGKSLASCVESREADSDTDISILARAMAAAGSDARMDGCELPVVINSGSGNQGI
                     TVSVPVLVYADRLHAGEEKTYRALALSNLTAIYQKTPIGRLSAFCGAVSAGAGAGAGI
                     AYLKGGDFEAVCRTVSNTLAVTPGMICDGAKPSCAGKIAMAVEAGIMGCRMNAEGEKF
                     LCGDGIVGEDADETISNTGRVAREGMRATNDTIIKIMIGD"
     gene            26738..27622
                     /locus_tag="ACZPCR_03705"
     CDS             26738..27622
                     /locus_tag="ACZPCR_03705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HIR1230013.1"
                     /translation="MEFREIATFLQAAQLKSFSKAAKKLNYSQGTVTIQIKNLEEELG
                     VRLFDRIGKQISLTSRGEQFYQYAVTLMKNMEEIKCSLSDSRELTGSLALGTIESLCS
                     SLLPPILSEYHRRFPKVNVSVVIDSPRVLLDRLNDNSLDIVYFLDKRISDPRWIKVLE
                     EPEDIVFAASSLHPLAGRSGLKLDEIISHPFLLTEKAASYRHILDQYLAAYGKQIRPF
                     LEIGNTDFIVHMLRENAGVSLLPFFSVRRDIEKGRLAALDAEDFHMQVWRQIVYHKDK
                     WITGEMAEFLKLAGAKPV"
     gene            complement(27772..28062)
                     /gene="spoVG"
                     /locus_tag="ACZPCR_03710"
     CDS             complement(27772..28062)
                     /gene="spoVG"
                     /locus_tag="ACZPCR_03710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007865261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030435 - sporulation resulting in
                     formation of a cellular spore [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HIR1230014.1"
                     /translation="MQITDVRVRRIEREGRMKAIVSITLDNEFVVHDIKVIDGEKGLF
                     IAMPSRRSTDGEYRDIAHPINSETRDMIQSIVLEKYQATASGLDEDGAAGQA"
     gene            complement(28122..29243)
                     /gene="glgD"
                     /locus_tag="ACZPCR_03715"
     CDS             complement(28122..29243)
                     /gene="glgD"
                     /locus_tag="ACZPCR_03715"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008720661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HIR1230015.1"
                     /translation="MRAIGIVLAGGNSKRMRELSNKRAIAAMPVAGSFRSVDFVLSNM
                     SNSHIQSVAVLTQYNSRSLNEHLSSSKWWDFGRKQGGMYVFTPTITAEHSDWYRGTAD
                     ALYQNLDFLKKSHEPYVVIAGGDCIYKLDYHKVLEYHIEKKADITVVCKDMEPEADVT
                     RFGLVKTNAEGRITDFEEKPMLATSNTISCGIYVIRRRQLIELLERCASEDRYDFVTD
                     ILVRYKNLKRIYAYKLDSYWSNIASVDSYYKTNMDFLKPEVRHYFFREYPEIYSKVDD
                     LPPAKYNPGAEVKNSLVSSGCILNGSVENSVLFKKVYIGNNCVIKNSIILNDVYIGDN
                     TVIENCIVESRDTIRANTTHIGAPDNVKIVIEKNERFTL"
     gene            complement(29240..30514)
                     /locus_tag="ACZPCR_03720"
     CDS             complement(29240..30514)
                     /locus_tag="ACZPCR_03720"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002577227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HIR1230016.1"
                     /translation="MIKKEMIAMLLAGGQGSRLGVLTQKVAKPAVSFGGKYRIIDFPL
                     SNCINSGVDTVGVLTQYQPLRLNAHIGIGIPWDLDRNVGGVTVLPPYERSKGSDWYTG
                     TANAIYQNLEYMENYNPDYVLILSGDHIYKMDYEVMLEYHKANNADITIAAMPVPIEE
                     ASRFGILITDEKNRITEFEEKPTNPRSNLASMGIYIFSWPVLRDALIKLSEEPGCDFG
                     KHVIPYCFSGGKRVFAYEYNGYWKDVGTLGSYWEANMELIDIIPEFNLYEEYWKIYTK
                     SDIIPPQYTAPDSKIERSIIGEGSEIYGQVINSVIGAGVTVGKGAVVKDSIVMKGTSI
                     GDGTVVDKAIIAEDVAIGANAEIGVGEYAPSKYDPKVYQFDLVTIGERSVIPDGVKVG
                     RNTAVSGVTESADYHDGALESGDYIIKAGGVQ"
     gene            30894..32285
                     /gene="asnS"
                     /locus_tag="ACZPCR_03725"
     CDS             30894..32285
                     /gene="asnS"
                     /locus_tag="ACZPCR_03725"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002605622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HIR1230017.1"
                     /translation="MDLITVREIYRDRDKFLGKEIQIGGWVRSIRDSKTFGFIVVSDG
                     SYFDTLQVVYHDNMENFNEISRLNVGAAILVKGTLVATPEAKQPFEIQADEVIVEGAS
                     SPDYPLQKKRHSLEYLRTISHLRPRTNTFQAVFRVRSLIAYAIHQYFQERDFVYVHTP
                     LITGSDCEGAGEMFQVTTMDLNSVPKTEDGKVDFSQDFFGRPTNLTVSGQLNGETYAM
                     AFRNIYTFGPTFRAENSNTTRHAAEFWMIEPEMAFADLNDNMALAESMLKYVIRYVLE
                     HAPEEMNFFNQFIDKGLLDRLNHVLNSEFGHVTYTEAVKLLEEHNDEFDYKVFWGCDL
                     QTEHERYLTEKIFKRPVFVTDYPKEIKAFYMKMNEDGKTVAAMDCLVPGIGEIIGGSQ
                     REDDYDKLVGRMEELGLKKEDYGFYLDLRKYGSVRHSGFGLGFERCVMYLTGMGNIRD
                     VIPFPRTVNNCEL"
     gene            32457..33527
                     /locus_tag="ACZPCR_03730"
     CDS             32457..33527
                     /locus_tag="ACZPCR_03730"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HIR1230018.1"
                     /translation="MKFIHTGDVHWGMAPDSDKPWSRERARDIRETFAAIIGKAGELS
                     VDFLFIAGDLFHRQPLLKDLKEVNYLFSTIPDVRIVMIAGNHDRVRKSSAVLSFNWAP
                     NVTFLSDEEFSSAYFEELHTEVTGFSYWTSEISEARLNDISAPDDGLIHILLGHGGDA
                     KHVPIDKEGLLKSGFSYAALGHIHKPEISQSLRMAWCGSPEPLDKTETGRHGIIYGEI
                     SETSLRITNLEFIPMAKLQYIPLMVNVTPNTTNTELFLRMSQEIEKRGSENIFRFRLK
                     GMRDPDISFDLESLMMRYRIADILDESEPQYDFSALFEEHSSDMIGFYIRALQKPDMS
                     PVEKKALYYGIHALLLTTDERS"
     gene            33531..35405
                     /locus_tag="ACZPCR_03735"
     CDS             33531..35405
                     /locus_tag="ACZPCR_03735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1230019.1"
                     /translation="MRFLDLYIKGFGKFHDTFVSFEDGLNLVYGKNEAGKSTIHTFIR
                     GMLFGIERQRGRAAKNDLYSKYEPWENSSTYEGQLRLESGGTIYRFERSFQKNKKEFI
                     IVNETTGREAEPTKALLDEILCGLSETAYNNTISIGQLKSATEGGMISELKNYIANMN
                     TSGNMALNITKATAYLKNQKRQFENQLTPEAAKTYTSLLGEIKNLEREISSPEYENQL
                     RSYAKERTDLKSAIEKKQEEREELLCRIEKGRQALAEFEFTDAQSVSAYLNHAEDIYR
                     QYLEAGQAASKKSRRGLSVFFGLLGLLLLLGAGYFFCWGLMPGNSFLPWMPETIDPLL
                     SGAAAAGASAVSFFAGALFRLKLRQEKKTASLCASNLSEIFRRHLGDGTISEKAMDAL
                     RNRMDDFIDLCSMIVRSEETVRRQMDDVEQLQGRQNQCSEIIEQQQRVQWELEKKLEH
                     LAELKDQASALRQIIAENDRIREEIAAIELAQETMKELSMSIRDSFGLYLNKTASELI
                     SGITGGLYTSMSIDENLGAFLNTRRKLIPLEQVSSGTADQIYLALRLAAARFIQNGTD
                     SMPLIFDDSFVLYDDDRLRQALRWLSEAYKGQIIIFTCHRRELDILKEEKIKHHVVTI
                     "
     gene            complement(35494..36546)
                     /locus_tag="ACZPCR_03740"
     CDS             complement(35494..36546)
                     /locus_tag="ACZPCR_03740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004222642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HIR1230020.1"
                     /translation="MEQKMMKALVFQGIGKLGLEERPVPVIKEPTDAIVRVTRSTICT
                     SDLHIRNGAVPRAREGVILGHEFAGEVVEIGSQVKTLKPGDRAAANCETICGDCWYCR
                     RGFVNNCEQGGWMLGCVIDGCQAEYVRVPLADTSLYRIPDGLTEEQALFTGDILSSGY
                     WGAKLCEIKTGDTVAVIGAGPVGMCAAQSALYLGAGQVILIDPNEERLKTARENRLAG
                     EYLSVTGQEAAEAVKGLTEGRGADAVIEAAGTEASFTLAWEVARPNGIVALVAMYEKD
                     PVLPLTRMYGKNLIFKTGGVDAADCRELLELLREGKLTTDFLITHRGPLSQILEGYDT
                     FEHKKDGCIKWVVTAE"
     gene            complement(36586..37767)
                     /locus_tag="ACZPCR_03745"
     CDS             complement(36586..37767)
                     /locus_tag="ACZPCR_03745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HIR1230021.1"
                     /translation="MLYEEKIIDTIPVGPLGLIPLKSCRAMGEKVDKYLTDWRRERES
                     EHKSTIAFAGYQRDSYIISASTPRFGSGEGKGALNESVRGDDIYILVDVCNHNLTYSL
                     NGMVNHMSPDDHFQDLKRVIAAVGGKARRINVIMPFLYESRQHKRTGRESLDCALALK
                     EIVDMGVENIITFDAHDPRVQNAIPLKGFETVQPIYQFIKHLLKHEKELQIDNDHMMV
                     ISPDEGGMRRAVYFANVLGLDMGMFYKRRDYTKIVNGRNPIVAHEFLGSSVEGKDVII
                     VDDMISSGESMLDVAKELKRRKARKVFVCATFGLFTNGLQKFDEYYENGVIDRVLTTN
                     LIYQSADLLSRPYYIDVDMSKYIALIIDNLNHDASLSELLNPTGRINRLVEKYKAGIR
                     D"
     gene            complement(37828..38823)
                     /locus_tag="ACZPCR_03750"
     CDS             complement(37828..38823)
                     /locus_tag="ACZPCR_03750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008396884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1230022.1"
                     /translation="MALSNSQYDSIMRIYNQAQLRQKHELDKRREEIYEKIPAVKELN
                     EEIASSAVKSARQLLAGDDRAAKGLKAKIADLCEERQVLLAAYGYPADYLELHYDCPL
                     CRDTGYADGRKCSCFKKREIALLYDQSNIREILKRENFSTFSYEYFDDTKPDPRSKKT
                     AREYMKQVAALCKSYVERFGETKDNLLFTGKTGLGKTFLSNCIAKELLDQGYSVVYLP
                     AVKMYEIFSKERFDYDATEEDRDRSSYLLDCDLLIIDDLGTELVNTFTTSQLFYCVNE
                     RLNRKKGTIISTNLPVNEMRDEFTDRVMSRIISQYTVIPLYGEDIRIRKKLLGRG"
     gene            complement(38810..39946)
                     /locus_tag="ACZPCR_03755"
     CDS             complement(38810..39946)
                     /locus_tag="ACZPCR_03755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HIR1230023.1"
                     /translation="MGNFIRNRLAHGVTVVSNEFIDNYMARANGEYVKVYLYILRNGG
                     RADSVADIADALNHTEADVRRALVYWEQEGVLELGDNRQTGLAAADAAPDRKMADRKP
                     AESKTAESKTEEKASAEGAESRLSQPSLEPGRKKSSGAVLNGLSRNEEFSQLLYIAQK
                     YLNRTFTPTDCDVFAYLYGQLHMPAELLEYLVESCAQNGHTSIRYIEKVGLSWHERGF
                     KTAEEAKTQSMGYKKDIFAVMRAFGLSGRNPADSEIDLMDKWFGAFGFTREIVVEACS
                     RTMAAIHKPSFQYADTILTDWSRAGVRTMKDVEHVTRLRREKKAREGKSGSQPEKRRT
                     NNRFHNLEEHGYNYDEMIWSMINSEDGGSGPGQPESTGGKHGAE"
     gene            complement(40199..41596)
                     /gene="murC"
                     /locus_tag="ACZPCR_03760"
     CDS             complement(40199..41596)
                     /gene="murC"
                     /locus_tag="ACZPCR_03760"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HIR1230024.1"
                     /translation="MYQIDFNKPQHIYFMGIGGISMSGLAEILMDEGFTISGSDSKES
                     ELTEHLRSRGAFVSIGQRAENIAAADEAGGAVDAVVYTAAIHPDNPEFQAAQQAGIPM
                     MSRAVLLGEMMRNYKEAIAVSGTHGKTTTTSMLSEIFLAAKADPTISVGGILPSIGGN
                     IRVGGPEFFITEACEYTNSFLEFFPTMALILNIEEDHLDFFKDLADIRRSFALFAEKV
                     PAQGSVIINAEIENWQEIVKNVSGTVITVGRDQACSYSAGSITYDELARPSFELYENG
                     VRRDIISLGVGGEHNVYNALAAIAAALTAGVSMEAVKRGLLNFTGTKRRFEKKGEFNG
                     VTVIDDYAHHPQEIQATLKTAGNYPHNQVWCVFQPHTYTRTKAFLDEFAEALSMADRV
                     ILADIYAARETDTLGISSRDIAERIEKLGTKVWYFPTFSEIEEFLKTNCQPGDLLITM
                     GAGDIVTVGEELLSK"
     gene            complement(41814..42317)
                     /locus_tag="ACZPCR_03765"
     CDS             complement(41814..42317)
                     /locus_tag="ACZPCR_03765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002577594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HIR1230025.1"
                     /translation="MNERNKKSVYLLTYSAAIAAIYIALTMMFMPISFGPVQFRISEA
                     LCVLPYFTPAAVPGLFIGCLLSNLLAGAMTMDVIFGSIATLIGAVGSYALRGNRFLVL
                     LPPIISNAVIVPWILRYAYGSTDLIPVAMVTVGIGEILAVGVLGSVLIRALERYKHMI
                     FRGVSAA"
     gene            complement(42990..43517)
                     /locus_tag="ACZPCR_03770"
                     /pseudo
     CDS             complement(42990..43517)
                     /locus_tag="ACZPCR_03770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004845962.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
     gene            complement(43545..43790)
                     /locus_tag="ACZPCR_03775"
     CDS             complement(43545..43790)
                     /locus_tag="ACZPCR_03775"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HIR1230026.1"
                     /translation="MFEEMHENGWNVAEMSYPFGRGINFSIEVEDVDMIYHKLILNEY
                     PLYRSMILNKYEVNGEYITQKEFLVQDPDGYLLRFTD"
     gene            complement(43847..43999)
                     /locus_tag="ACZPCR_03780"
     CDS             complement(43847..43999)
                     /locus_tag="ACZPCR_03780"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230027.1"
                     /translation="MKNTAITYSVCQVDGKLELTEQSEGMLLVRKGKKMERKRTRKSE
                     VKQNKN"
     gene            complement(44445..45323)
                     /locus_tag="ACZPCR_03785"
     CDS             complement(44445..45323)
                     /locus_tag="ACZPCR_03785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008396899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HIR1230028.1"
                     /translation="MKLSTSTNIVFERPDKSIMPMEDMMELAFAAGFDTFDISFYDWS
                     LPHSPFLTDQWEKWLARIERKKDELGVSFGQCHAYTYNFCAPMTAAERARHEELVERS
                     IYCCAALGSPLCVTHPETDFDSPALVKSSKEKNTAYFQELLRKTEKYPMAFAIENMCD
                     YSIAPKRKYCATPEEMVDFVTSFDDERMGICWDFEHADIMKQDQRQSLLYIGKHLKGT
                     HVSDTHSMTDPDLMHVMPLFGTVNWNEVVQTLREIGYTGYFSFEANNYGNYFPDELLP
                     TALRLAREIGEYLMKL"
     gene            complement(45441..46382)
                     /locus_tag="ACZPCR_03790"
     CDS             complement(45441..46382)
                     /locus_tag="ACZPCR_03790"
                     /EC_number="3.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HIR1230029.1"
                     /translation="MTDRITRKVIIDTDPSADDAVALMLAMVSPELEILGMTAAFGVC
                     DSARSIKNILKIQTLCGREEIPAVQGAEMPLVRRMEFDDAYCGCDGLSQTGLPDPAKK
                     EEPGEAWRFMAETVKRFPGQVSIISLAPMTNLALMIQNDPAAALAAAGIYTIAGSYGL
                     RPDYENLNPRPEWNLAQDPEAAAAVFGSGIPITAAGLDVTRRLDNSMMDRLLARAGEN
                     EKTKFLRRAVQFNLDHGLDPYSLLVDSAAVCLALCPEIAKTVSGHVIVETRGEYTTGQ
                     TLFGNSGRFKKQGSFVQAAWDYDWEKLLSFLEKRVFS"
     gene            complement(46389..46910)
                     /locus_tag="ACZPCR_03795"
     CDS             complement(46389..46910)
                     /locus_tag="ACZPCR_03795"
                     /inference="COORDINATES: protein motif:HMM:NF024808.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HIR1230030.1"
                     /translation="MQQGNGSSSRIPTIKELVGDSFNWGVAQIPLVTSDDIGGAYPSG
                     SGLFLLNRGDDETVKAAWEFEQYMVSPEAQAMWLEGAGYVPVNKNSAELESYQNAIAE
                     TPQLAVPGEVMMKANEAVLAPFVPNSDAVDTTIKDAMLMFGNGQASAEDTKTAIIDGC
                     NQIFNDYYRANGE"
     gene            complement(46859..47491)
                     /locus_tag="ACZPCR_03800"
     CDS             complement(46859..47491)
                     /locus_tag="ACZPCR_03800"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:TIGR01484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HIR1230031.1"
                     /translation="MADISSKVRLVVSDVDGTLVGADCVMGEGIRQLAQLLSEQHIAF
                     TLASGRPVGMLEEYKKALNITLPVVASNGAAGHDGEKFIWEELLPADAVRRTVEEADR
                     MGLAVFLTDENTEGVYRQNDYIRRKSQESGLYKHLIHPEGDEWNGQRLQKLMIIDPDS
                     PGQCDMLRPLLEEEKNRIHVVRYGSRCFEAMPEGCSKGTGAAPVFLPLRS"
     gene            complement(47707..49308)
                     /locus_tag="ACZPCR_03805"
     CDS             complement(47707..49308)
                     /locus_tag="ACZPCR_03805"
                     /inference="COORDINATES: protein motif:HMM:NF012301.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1230032.1"
                     /translation="MHLMLISHDRNTIRALKIALSKTTEDILPITSAYSREQAVSQLK
                     KEPAGLIVCDADMPGNEGIEILRELRGQNYRGGVIVISASCSPELTREALRLEAGDFL
                     LKPVEENQLRSAVKGILARQRKREEEELKKEYGDCWMENHMAIKELFWKDVCLGRIRN
                     DPEIISRKARGCNIRLDADARYRMVLITIKNVEEVQRRWGEELCQSAIQNLAKGVVKG
                     NVQTSQVIVIYTRVVVILDEKEGERFREIGPGLVERCRDMFGAQILCYVSGDIFCEEM
                     EKTYSRLLRFSKDDVLCQDSIQYVTQRDGEREEGDRRLKERIILPSDWGELIFAGQTD
                     GLVEKIRRFLVEQAKKKRLDEMSFRILQQDILQMFFACMEYREIKAHQLFEDEEVYQH
                     YKTACFSIDDMCRWIRMCMELITRLSFPDGNSSGAELAGRIKGMIKENLKTGISRKEI
                     ARELNLNPDYVNRIFKKETGMTVKEYAIKKRMKQAEHLLKHSDLPVSGIAAEVGYDNF
                     SHFIRMFRKETGYTPKQYKKRFREV"
     gene            complement(49682..50794)
                     /locus_tag="ACZPCR_03810"
     CDS             complement(49682..50794)
                     /locus_tag="ACZPCR_03810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004853738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HIR1230033.1"
                     /translation="MSLSFKAVIEFLKKETVLAVSGLLALLSCFLVRPDREYLNYFSS
                     NMGTIIVLFCLMAVVAGLSGLGVFRYVGERLLERIQSERGIVFLLVFLCFFGSMFITN
                     DVALITFVPFGIMILKMAGMTGRLCRVVTLMTIAANLGSMFTPMGNPQNLYLYSISRM
                     TLSAFLRLMLPHTAAAALLLCLCVFFGVGKEKTCVTMTEQTKKPETSGTVYYLLLFFI
                     CLQTVGGVLPAPGLLLAVVAAVMYRDRILFRKVDYSLLLTFLFFFVFIGNMNRFPPFR
                     EFVVNMIAGHEKVAAIGISQVISNVPAALLLSNFTDQWEQLIIGTNLGGLGTLIASMA
                     SLISYKQVAAEYPEKKGRYLAVFTWWNLLFLAVLIW"
     gene            complement(50791..51999)
                     /locus_tag="ACZPCR_03815"
     CDS             complement(50791..51999)
                     /locus_tag="ACZPCR_03815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009242460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HIR1230034.1"
                     /translation="MLTSLAFIFLAGLAMAGICGRLGLPRIIGMLFTGILLGPNVFNL
                     LDSSILLISPQLRQMALIIILLKAGLSLNLSDLRQVGRPAVMMSFVPASFEILAFLLF
                     GPFILGISRVEAALLGSVLAAVSPAVVIPRMVQLMEEKYGTDKSIPQMIMAGASCDDI
                     FVIVLFSTFLGMAQGESVRAADFLNIPVSIVLGILLGAVFGYGLSRFFERAYEKKRYI
                     RNSMKVVIVLGTSFLLMSVEAWLEDVVSVSGLLAVVSMACMIKIKSAPIVSKRLAEKF
                     GKLWVAAEVMLFVLVGAVVDIRYTMGAGAAAVLMIAIALGFRAVGVCLCLAGTKLNRR
                     ERLFGIIAYLPKATVQAAIGSVPLAAGLPCGQLVLSVAVLSILITAPLGAVGMDLTYR
                     KFLEKEKEVS"
     regulatory      complement(52092..52163)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            complement(52288..53250)
                     /locus_tag="ACZPCR_03820"
     CDS             complement(52288..53250)
                     /locus_tag="ACZPCR_03820"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HIR1230035.1"
                     /translation="MSFKILLPQPILESGRQYLLDKGYELVDGSGFEEEDIIRDIKGC
                     DGMIVRTAKITRRILEAADSLKVIARHGAGFDGVDLEAAREKGIVVLYAPRANSQSVA
                     GLAIFYMLHCSRNFKLVQKLYRDDYRFAKFNVEKHELNGKTLGLIGVGNIGGLVAKKA
                     ALGFDMKVLAFDPYAKDLLDYIELAGSREEVFEKADYVSLHVPATPETVNSVGAKEFQ
                     LMKPTAFLINTSRGTVVDEEALIEALKEKQIAGAALDVLKKEPMEKDNPLLDMDNVVT
                     APHIGGATKEASSRSSLICARGIDDFLSGRKPEFVVPPMRDMVK"
     gene            53680..55659
                     /locus_tag="ACZPCR_03825"
     CDS             53680..55659
                     /locus_tag="ACZPCR_03825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HIR1230036.1"
                     /translation="MKLSSAAPGGQAADIVIFAASETFAQTARELILERRLENHIAVT
                     EATGERTLKLALQFAREGSRVFISRGRNTKLIERHVSVPVINVPYLCEEIYSSFLAAG
                     APPERVAMVGFDRAYNIMKTFRRISGLDVQLIEPQSPGTVIKELREKLRPGTEALIGG
                     FSVKRAISEIQDLGLRHIPLTVEPSNISLAIDSALNILASMDRKDEFLTTISTTINRI
                     SNAVMNFDVNGKLLFSNARADHMPQSVKKYLFTGEAAFYLELDGRTPADSRTAPKKEQ
                     ILHVGYDTYVAEYLPVIVNRRLKSIVVIVSSENSIQMAEKRLRLSQSKRGYTAKNHFH
                     DMIGNSPVFQETIQLAKKYARSQSSVLITGETGTGKELFAQSIHNASSRCSEPFVAIN
                     CAALPQSLLESELFGYVKGAFTGASKEGKMGIFEMAHRGTVFLDEIGEMDLNVQAKLL
                     RVLQEREVCRLGDDKIIPVDIRIISATNKDLEELVRQKLFREDLLYRLNVLELRLPPL
                     RERTGDIPLLIKAYNGKQNHPVTFLPEAVRLLEAQPYPGNIRQLFNLLERTITLSDGD
                     MIEASQLANILHLPFSSALPDCGSKEPAFPDPASEASSSGCSVSSLDSAMVLCEKERI
                     LETLRKNRGRRKETAEQLNISPATLWRKMKKYDIF"
     gene            55878..56879
                     /locus_tag="ACZPCR_03830"
     CDS             55878..56879
                     /locus_tag="ACZPCR_03830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008373277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HIR1230037.1"
                     /translation="MTTIFLGMGLLLLTLAGFSLFSMKAPKGSAAMSGLANAAVATFL
                     VEAVHRYISGDLLGSAFLGEVGSVSGSLGGVASAILIPISMGANPLFAVVAGVAVGGY
                     SILPGFVVGYLIGFIAPVIEKHLPAGLDTILGALLLAPIARGIAFLTDPVVNAAMGYI
                     GNTITAATDQSPVLMGFLLGGIIKMICTSPLSSMALTAMLGLTGLPMGIAAIACFGGS
                     FTNGIIFAQLKLGKPSNIAAVMLEPLTQAHIITRHPIPIYGSNFFGGGLAGIAAALLG
                     IVNNAPGTASPIPGLLAPFAFNPPVKVLIALALGAVGGTLAGFAGSIVFKKFTQDEA"
     gene            complement(57063..58646)
                     /locus_tag="ACZPCR_03835"
     CDS             complement(57063..58646)
                     /locus_tag="ACZPCR_03835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0071705 - nitrogen compound transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BCCT family transporter"
                     /protein_id="HIR1230038.1"
                     /translation="MGEKQKTKLSMRPMTFFPPFILLSIFVILSIVNKDGFLGIVNAI
                     NNAIIAHFGWAASILALVITVVAVIAAFSKFGDVRIGGEDAKPELSNFAWFTIALTTT
                     MAAGVLFWGPGEPIAHYMSPPTEIYGVEPKTPEALKFSMETMFLHWTIVPYAMYTVPA
                     VVFAFMYYNGKKPFSITSEMAPLLGKRAYRPMVMQIVDAVTLFSIGAGMAGSVAQAFM
                     NVSGGISKLTGLPSDPKLWLMVGIVVGAVSIATAISGIQKAMTKVSNINVYGFAIFLI
                     FLLIFSNASFLFNLSTEALGGFAGTFLERILITGQSAGSQWPQWWTTFYWFSWMAWAP
                     TSGAFMGRIAYGRKVKHILGMYVGVCATISAVWMMLVSGTSLWMETSGTVDLCASYAK
                     GVENVPYDMLGAMPLSAVIIPLFIILIFLSTVTACNSNMIAMAGISTRGISPDNPDAP
                     NWLKLVWGVIPMAVGYIMIASIGVDGVKIIANFGGMFAALIMIGAAASLGILIVNHKK
                     YDLTIKGARDEIFGEVQNE"
     gene            complement(58647..59474)
                     /locus_tag="ACZPCR_03840"
     CDS             complement(58647..59474)
                     /locus_tag="ACZPCR_03840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HIR1230039.1"
                     /translation="MEQYKLALVQMNCAFGEQEQNRKKAEQYIREAAKKGAALVCLPE
                     SFNGGYLGSRILDMKAMAEPLDGPSVSHMRSLAAELHIHIVAPVLYLTENGETENTAV
                     MIDDEGNVVGTYSKTHPVGDERLYFQRGTEYPVWETKLGKIGIVICYDVCFPETARIL
                     ALKGAQLILVPAAWRASYYFKEWWDLNLSCRALDNLVYVAAVNRCGPSDDEIFAGKSQ
                     VIDPTGKVLSAFGVEEEGVLFQEINLAQVKQEREFNTVLSDRHPEDYRELLKEWREQ"
     gene            complement(59648..60586)
                     /locus_tag="ACZPCR_03845"
     CDS             complement(59648..60586)
                     /locus_tag="ACZPCR_03845"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HIR1230040.1"
                     /translation="MKMREVVFYSEGTKMVGTIYLPDDYKEGEKRPGIIANSGWTGLN
                     KVYPAMFARQMTKYGYVCMGFDYRGFKPSGGIGLMEKYTTLEMEVDDVNNAVTFFKHQ
                     PEVDPEHIALIGWGVGGAVCVTAAYRDKTVKAVATLNSFTDGRRWMRMGMGNDKYNKM
                     LRTLEEDKWKRVSTGDPVLRHPYEFYPNIDESGDFYVEKTLKNLNGGLEDSIEGDYKE
                     PFPTPMSSVIAESFVRFNVQDILPKLAPDCAVFVGHGKYNELHDREEADDAYRLANEP
                     KALYFVEGKHNEWMFDNDPKLVGLCDAMNEFFAAHI"
BASE COUNT        13950 a        17340 c        13264 g        16139 t
ORIGIN      
        1 cgccagcgtt catcctgagc caggatcaaa ctctcatgtt aaagttttga ttccagtcca
       61 aaacttagct tggctaattt ttaaaccgtt ttactgtttt ttaggttgtt ctgaatgttc
      121 tctcgaactt caaggctcct gcgccttttg ttcttagaat tttcagggtt ttacatactg
      181 ttcagttttc aatgttcgtt gttgtttctc aacagcaact cgtttatctt atcacaactc
      241 atcgtgtttg tcaacaactt tttttattta tttttcgaag ctctttcgaa cttccgtgcc
      301 gctctcagcg acgcgttata tcttatcaca acctcgtgtc agtgtcaagc acttttttga
      361 agttttttaa gattttattt tcatccattt ctttcagatg gtatcctcag aaaaccttga
      421 ttttaaaggc cggatgagtc agcacttgtt cagcgctggg ttaaactata ccacttacag
      481 aggccgttgt caagggaatt gttcttattt ttttaaacaa ttttcatttc ctctcctcaa
      541 gcactacatc tatcctttta tttctttgca taccatatct tgtggttttt gaaatccctt
      601 gattttacaa catatttttc tatatttttt atattgtatg taaaatatgt tttgtttaat
      661 caatttgagt tctcatacat gcaaacaccg ggacatgcaa cttcaagcca catgtcccgg
      721 cactctatga gactatatta cgttttctct gtgcgttctc tgcgcgtcag cgccaaagcg
      781 gaagaaacca tgcagcggcg tctcccgctc tgttcatatt gcagattaca aaaatccctt
      841 catcaaggac gcagccagcg ttaccagcag attgtgttca tataaataag acagccagct
      901 gctctcttct atcagtctgc caagctccgc tccccactct gctgcagaaa aggctgtgac
      961 aagcaggcag aacagccaca aaaatacaag gccttccgcc gctcccaaag ctgcgccggc
     1021 cagtttattg actccataaa tgacaggcag cctggccact atgtccagac atctggagat
     1081 aatctggagt gtgccgaaca gaactccaaa taagaggaga tatacggtca gattgaccat
     1141 attattaacc aggtatcccg tcacataccg ggagaaggtt tccgctccca gcaggcggta
     1201 aacttcatgg ttattattgg ctacaaggcc ttccttcagc cgttccggaa gcttcaagcc
     1261 ttctattttc tggcgctggg ccgcaggagt atctgcgtcc gcgctctcat ccattccaat
     1321 cgcctcgcca atggcgtttt caatcgtctg gtaaatttct gtgtgctgct tcagatagga
     1381 ggtcacctgc ggcattacgg cattcaccgc tatcagcgta acgatcagag aagcggccga
     1441 tacagccatt ctgataaatc ccttataatg tcccatcaaa atcatagcgg ccagatagac
     1501 ggccgccgcg attgccaacc agttctgcat agattttccc tttctcttct ctgtgtaggc
     1561 tgctttttcg tttcagcagt tttttataga atcagcttct caatcactct ggccaccccg
     1621 tcttcctcat tggatcgggc aatgaaatca gccttcttct taagcgccgg atttccattg
     1681 tccatcgcca ctcctattcc ggcaagctcc atcatgctga gatcattttc cccatccccg
     1741 aaggccatgg tctggctggg ggaaagtccc agataacggg ccagaagcaa aatcgcgttt
     1801 cccttggaag ccccctcccc gttgatctcc agattgctgg gcatggatga ggtaacggca
     1861 attccttcca gctctgaaag cgcctctctc acctggcgtt ttgtctctct gtcgtaccct
     1921 ttaaaataaa tattcatttt atcgagagcc ggatgggttt cattcagata atctctcaga
     1981 gaagggaggg gttctctggt tctgcggatt aattcgcaaa tctccggacg gatttcatag
     2041 tattcaagcg tatctaagaa acgcctgtca gcctttcctc tcccatctgc gtaagcgtcg
     2101 tacatcagcg tacagccgct tattttatca atgatctgca ctgctctctg ccagtctaac
     2161 gctctgcgtt caatcacctc tcctgtcgcc gcattctgaa tctgcgcccc attcgtcagg
     2221 attgcatact gtatcccctt tacctgtctg actgcagccg ggattccctc aaaggtcctg
     2281 cctgtacacg gcacaatata aatccccttt tcaatgcagg cctccagcgc tcttctgttt
     2341 ctctcagaaa gctgtttgtc ctctgtcaaa agcgttccgt ccagatccag ggcaattaac
     2401 ttgatatcca cgttccttcc tccaaatttt tctcattctg cttttcataa ttatgtaaac
     2461 tgcaccagaa gatgccgacg ataaattcag gccagcggca tcccttcgga tggctggcct
     2521 gaatcgacat aagcgtttaa acgctctggc gctgtgttct atttttaatc aaagaaatgc
     2581 ttttccttca gaatcagaag accatcttta tcgtatttag atgagaagaa tcctccgaaa
     2641 gacggtttct cagcccggtc tgcggcttcc tcgatgagtt cttccgcgct ttctcttgtc
     2701 agaggaacgc cgtcctcctc catcatctca gcgcgctcgt agagggcaag catgctcttt
     2761 cctgaaatac tgcagtcaat ctccgacgca tatttgcagg catactgtgc gaattcctcc
     2821 acatccattt ctctgtcgtc gccttcctca gaatagccgt cagactcctg ttcctcattg
     2881 tcccaggagt cctcatacgc ctcctcatcc tggtactcgt cctcctgata ggagtcatgt
     2941 tcctcgcgct ctctgccgcg ggcgccgtca tcctggaagt cctcttcata aaagtcccgg
     3001 gcgtcataat cctcttctgc aggctctttg taatcgtcct ggaactcctg ctctttcgcg
     3061 cgttcttcct cttctatacg gcgctgacgc tccgcctcgg cttcccgttc tgcctgaaga
     3121 cgagccgcct ccaatctgcg ctcctcctca cggcggcggg cagcttctgc ctcttccctg
     3181 cgtctgtttt cctctgctgc cgcagcctcc tccaggcgct ttctctcctg ctccgcctca
     3241 tattctgcct gacggcgggc agcctctgcc gctgcagccg cctgtcttct cttaatctcc
     3301 tgttcctccg gatcctctgc cttctcctgc gctctgcagc caatatactg gaacttgtcc
     3361 gccagatcag gattttcatt gtgcaggcgc tccattctgg atggagtgtc gatgagaacc
     3421 acaatcatgc cgctcttatc tgcttccatc agctcgctta aatcacggac ggagaattca
     3481 tccaaatctg ccgcacgctc tacgatcaaa tctcttccgc tgaggcggtc tgccacagaa
     3541 aagatacctc ttctgtttaa attctgggcg ctgattttgg ccacaggatt cttggttccc
     3601 agttctctgt gaattttctt taaggattca agggccaggg aaagaccgct ctccggatcc
     3661 tcggcctcga tcatcaggtg attgctgtca ttttccactg gctctaaatc ccagtcttca
     3721 atcaccgtct cctcctcttc ctcataagct ctggcaatcg cttcctcccg gcgggcagtc
     3781 tctgactcag aagttctgtc ctcctctgcc cctgcctgtg cgcttcctgc agttctgctg
     3841 tcggaagctg ctgctgtctg cttcaaagcc tccgccttgc cctcttccgg ctctcttccc
     3901 actcttctga tgtcagtgag cactctcgtc tctcccaggg aatcctcctc atcgtctgca
     3961 tggtactctt cctggggaat tctggagatc tcccgggcca gctctttctc tgcctgctcc
     4021 tccccgagtg aagcgccgac agccattctg cgcgcctcct cagcctctga atcgtcgtca
     4081 ggctcgtcaa aatcctcgtc cgcttctatt tcctcgtcct ctctgtgacg ccggccggaa
     4141 ctgtattcct cctccacagc tctcagcttt tcctcatact tttctctgtt ttccaccaga
     4201 tccatctgat atttggttaa aggcgcgtat ttctgtttca gagccatggc cttatctacg
     4261 tactttccga ggccgaagag cagcatcagc ttatcgcaga tgcggacgca gtcttcttcc
     4321 cgtccggcct tctggtacag ctcagccagc ttatacagcc atttttcatc cagctcgtcc
     4381 tggcagtagc gctccagaga gacaatcagc tgctctaacg gagcctgttt tgcctcaaga
     4441 atcagataac gaagcagatt ctgtctggga tcctccccgc acagctcgca gaattctctg
     4501 tagtatgcct cggcctcaga cacattgccc tctctcagag ccagatccgt cagcttaaac
     4561 agaagcccct ttccaatagg agcgcgctca aaggccaaaa gaaggatatc cttcgcctcc
     4621 tgatactcct catttctctc atacacctgg gaaatagacg ctaacagact ggtgctacgg
     4681 acacgtctcc agtcgattcc atcggcgatt ttcatagctg tctcgtaatc gcctttattt
     4741 accagctttt taatctgttc aacctttatg ttaaactcgt acttatccat ctcttttgca
     4801 tctcctaacg cctgacagac aggcctttct atatgaagat tttctatcta ccgtttcctg
     4861 ttacagctcc gttctgcctt ccagcgcccg aagcagcgtc acctcgtcaa tgtactccag
     4921 atctcctcct accggcactc cgctggcaat tctcgtcacc ttaatgcccg taggcttaat
     4981 cagcttgctt atgtacatgg ctgtggtttc gccttccagg ctggaattgg tggcaatgat
     5041 aacctccttc acctcttctc tctggagtct ggccatcagc tccttcagcc ggatatctcc
     5101 cggcccaatg ccaagcatgg gagaaatcgc tccgtgcagg acgtggtaaa cgccgtcgta
     5161 ttttcccgtt ttctcgtaag cggccaaatc tctcgtgttt tccaccacca taatgacact
     5221 gtgatctctc ttctggcttt cgcagatagg acagagttcc ttgtccgtca gagtaaagca
     5281 ttcccggcag tagcgcacgt ttttcttggc gcttgtaatg gccgacgaaa gacgctctac
     5341 ctgctcctcc ggcatattga tgatatgaaa cgccagtctc tgggcggatt tatttccaat
     5401 gccgggaagc ttcgacagct cctctattaa ttttgttatc tgactgctgt agtaatccat
     5461 gttagaacgg gaagcctccg cctaagccgc ctcccaggcc gccaaggccg cctgtaagct
     5521 tcgccatggc ctgagcgctg gcatcctcca tctggcggaa cgcctcgttt gtggcagcca
     5581 caatcagatc ctccagcatc tcaatatcat ccgggtccac aacctcctca gaaagcttta
     5641 cggagacaac ctccttcttt ccggaaacag tcactgtcac ggctccgccg cctgaggaag
     5701 ctgtgtactc cttctcttcc agctcctttg tcgtctcctc catctggcgc tgcattctct
     5761 gcgcctgctt catcagattt gtcatattcc caggcattcc tcccgggaaa ccgccacgtt
     5821 ttgccatggt gtttatcctc ctaaaaataa ataaatgaaa ttatgtgact gtgtcactgt
     5881 gtctgtcagt cctcgatctc tatcacgtcg tgaattacct tcaaatcctc gtcgcttaca
     5941 taaaccgttg atacgggaac cgaggtttcc cgaagatggg ctttaaattc aatcgtcctg
     6001 tggtaatcag cctccaccag ctccttaagc tctgccaggc ggttctcctg attcataata
     6061 ctatagttat tgacgtctgt aaactcaatg gacaggcatc cttcccccgc cggctttagc
     6121 gaggttccct gaagggccac ccgcatggcg ccgcccagct tcctggaaag ctttccccag
     6181 tcgcccttaa ctgccatcag atcctcatac tgggccttcg gaagcaccac tgtctccggt
     6241 tccgccgtat gttcaccggc cgcctcagaa atcgaaactc cgcctgctgt tccctgcgcc
     6301 gcagacgcct gtccggccgc tgccagggca gccagctcgg ccggagacgg aatctgggct
     6361 atcctggctt ccagctcaga aatcctctgg agcacagaat ccagattctg ctccatggaa
     6421 ggctttgtca gcttgataaa cgctatctcc aaaagcactc tcttctggct ggcatagcgc
     6481 atctgcccgg acagctctga gaaaatgcgg atatagcgca tcagcgtatt tccatctgtg
     6541 agggccgctt cttcctttaa ctggcgcaga ttttccatgg acgtatccag gatattctcc
     6601 gcgtcgtcgg cagactggac aatcagaaga tttctcagat accagataaa atctgtgaca
     6661 aactgcgaaa gctccctgcc ctgaatcaca atctcctcaa tcgcgctgat gcagtccttc
     6721 gcccttccct ccacagccgc gcgaaacagc tgggaaaata cactgttgtc cacagctccc
     6781 agcacttcca gcacattgtc gtaggtgaga gactccccaa aatgaaaggc cgcacactgg
     6841 tccagcaggc ttaaggcatc tcgcatggaa ccgtccgccg ccttggccac atagcgcaga
     6901 gcccgttcct ccgcctcgat atgctccgcc tctgtcagtt cctttaagcg gcctgcaatg
     6961 gtatccaagg aaatcctctt aaagtcatat ctctggcatc tggacagaat ggtaatggga
     7021 atcttgtgaa cctctgtggt ggccagaata aagattacat aggacggcgg ctcctccagg
     7081 gtctttagca gcgcgttaaa ggctccgatg gaaagcatgt gaacctcgtc gataatataa
     7141 actctgtatt tcccctctgt aggcggatac tgcacctgct ccctgatttc ccggatgttt
     7201 tccacaccgt tattggaagc cgcatcaatc tccaccacgt tcagggaagc gccctcttta
     7261 atccgcttac aggtttcgca ttcattgcac gggcttccgt ccttcggatg ttcgcagttg
     7321 accgctctgg caaaaatctt cgcgatactg gtctttccgg ttcccctggt gccgcagaac
     7381 aggtaggcat ggccaatccg gcctgactcc acctgatttt ttaatgtttt tacgatgtga
     7441 tcctgcccct ttacgtcctc aaaggaggca ggacgccact ttcggtaaag ggctgtatac
     7501 gacatagcct cttaactcct cgctctattc gtcgccaaag ctgattccga tagccttagc
     7561 gtcccggatc atatcgcagg acggatccac catcttcagc ttgcctgccg cctcagacag
     7621 aggcacattg acgatctcgt tattcttaat agataccata taaccgtact cgccccgcat
     7681 aatcaggcct gccgccgaag ctcccaggcg ggtggacagt acgcggtcgc agggagtcgg
     7741 ctctccgcct ctctgcatat ggcccggaac ggtcacacgg acctcctggc ctgtccgctc
     7801 tgtaatctta gcccccagct cataggccac agacggatag acggggctgg acttcttctt
     7861 ttccttcagc tccttcttag tcagggccgc atcctctttt gagatagctc cctcagccac
     7921 agccagtatg gtaaaattct ttcctgcttt tgttctcttc ttgatggcat ctaccaccac
     7981 atcaatatcg taaggaatct ccggaagcag aataatatcc gcgccgccgg caattcccgc
     8041 gtacagagtc agccacccca ctttatgtcc cataatctcc acaatgaaga cgcgtccatg
     8101 ggaggccgct gtggtgtgaa tgcagtcaat ggcattggtc gccacagtaa ctgcgctgtc
     8161 aaagccaaaa gtcatgtccg ttccccagag gtcattatca atggtcttag gaagatggat
     8221 cacattcagc ccctcctccc tgagcaggtt ggccgtcttc tggcttccgt ttcctccgag
     8281 aaccacaaga cattccagct ttaatttata ataggtgtgc ttcatggacg ccactttatc
     8341 aagtccgttc tcatccggtg ttctcatcag cttaaacggc tgtctggaag ttccgagaat
     8401 ggttcctccc agtgtcaaaa taccggaaaa gtcagatggc ttcataatat ggtagtctgc
     8461 gtacatcaga cccttgtatc cgtcttcaaa gcctacaatt tccacttcgt cattgtattt
     8521 tttataaagc gctttcgcta cgccccgcat ggtggcattt aaactctggc agtcgccgcc
     8581 gctggtaagc ataccaattc gtttcatcat gtcacaccct ttctgcttgt ctgtatatag
     8641 gtatttcagg ttacactata cccattttgt aattataata caatcttttc ctgcgggcaa
     8701 ggaaaaaatc tttacggaaa gcttaggaat tatgcggttt taaaaggaaa aggatatatt
     8761 ttccatgttc caatttaagt cactggaaaa tatatccttt cctttttaaa gcagttttgt
     8821 gcaagggcat atataccccc acaatgcaaa aatctccccg gcattatccc ggagagatca
     8881 gtaattcttt attattttaa tccgcacatt ctgctttgaa tgctcttcac agacgttacc
     8941 cttgcagtta actcggccca ggctccctcg cggcacacga gagcttccac ttagtgctgc
     9001 tgcattcctg ccctgacacg gttcatggat tcccattgcg caagacccaa acttcaacgc
     9061 cacttacaag gggcagctct gcaaacaagc accctgggca gaatatcacc cctgctatag
     9121 cggattgcag gtacagggca ccgctaactc cccggctgtg cggaatcttt atgacataat
     9181 tatattttat cagctaattc agtatacacg gcaggggagg ttttgtcaag accgccagaa
     9241 ggaaccgaac ataatctgca aactgtccat ttactcccat ccaaattcat aatataataa
     9301 aaaatacaga tacttttcag aaaaacattc attttcccca ctcgaaagga gcacgcatat
     9361 gaatgacaaa accatgttca atctgaccta tggcctgttt gttctgactg ccagcctgga
     9421 cggcaaagat aacggctgta tcatcaacac tgccggacag gtaacagctg tcccaaaccg
     9481 aatcagcatt gcggtaaata agagcaattt cacccatgat atgattcttg cttccggaaa
     9541 atttaatgtt tctattttaa gcgaagaggc tgatttttct atttttaagc ggttcggctt
     9601 ccagtccggc cgtgacgtca ataaattcga cggctatgaa cacgctgtcc gaggtgaaaa
     9661 cggaatttat tatgtgacag aaggtaccaa cggttttatt tccgcacagg tcgaaactac
     9721 tctggatctg ggaacccaca ccctgttcat cgcaggagta actgacatgg atgttttaag
     9781 cgacattccg tccacaacct acacctatta ccagaaccac attaagccaa aaccgctgcc
     9841 aaagacagaa agcgagaagg gcgttaccat ctggcgctgc cgcatctgcg gctacgaata
     9901 caaaggcgac gttcttccag atgactttat ctgtcccatc tgcaagcatc cggcctctga
     9961 ttttgaaaaa attaccggct aaaccaaccg gatcagctgt aaacgcagca ggatctcagg
    10021 cggctttcaa aaataaatga ggcccctcat cttaacagat taacagacaa aaaagcgccg
    10081 ttttcccaca cggtaaacaa ccagctggaa acggcgtttt ctgtttttac atacgctttt
    10141 ctgcttttcg cttttttgat tctcgcttta ttactcctgc tcttgctcgt tctgctgctc
    10201 tttttttcgt tcttttttct tctcccgcag ctcccggaag aagtccttca gcatctggga
    10261 acactcctcc cccagcattc ccacctctgt ctccacctga tggttaaagc cgtcttcatg
    10321 aagcagatct agcactgatc cggcgcagcc ggccttggga ttcatacacc ctatcacaac
    10381 cttcggtatc ctggcctgga caatcgctcc cgcgcacata gggcagggtt ccagggtcac
    10441 atacatggtg catccctcca gacgccagtc gcccatagcg cggcacgctt ttcgtatcgc
    10501 aataatttcc gcatgagcca gcacatttcc gtctgtggtt ctccggttat agcctcttcc
    10561 tatgattttt ccttcatata caatcacgca cccaatcgga acctctccca gcttccaggc
    10621 tttcttggcc tgccggacag cttcccgcat acagcgctcc tcttctgtca gttttttcat
    10681 tccattctcc tgctttcatt ttccctattt tccattaagt atagaccaca gggcctctcc
    10741 ctggcaatag ctgagaaata aaacaaaaag aaagggatga aaaggatgaa tcccggatcc
    10801 acttggccgg ccgtctgatg atatggtata ataggagtac ttaacgaata cgagccgcag
    10861 gcgaagtatg aggttagtac gagtcatacc cagacactta gcgaggtctt ttcgagctta
    10921 gtgaatgtgg tataatatga acacttggcg aggtttttca cgagtctagt gagaatatat
    10981 accagttcca caacatgatc cattggaggt tttaccatga atatatgcgg tttacaaaaa
    11041 acaactcttc tcgactatcc aggccgcgtg gcctccacta tttttctggg cagctgcaac
    11101 ttccggtgtc ccttctgcca caacagcgat ctgctggacg gctgcgcaga gcatcccttc
    11161 tccgtgccgg acgtactggc ctttctgaaa aaacgttcca atgttttgga aggagtctgt
    11221 attacaggag gggaaccgac cctgcatccg gaattggagg attttatcag aaagatacgt
    11281 tcgctgggac tggctgttaa gctggatacc aacggcttcc ggccagaggt tctgaaacgc
    11341 ctatgcgaac agagcctgat cgattatgcc gctatggata tcaaagcggg ccgggcaaac
    11401 tatggccggg cctgcggcgt accgggaatc agccttgctc ctatcgaaga aagcgttgcc
    11461 tttctgcttt caggggctgt tcccttcgaa ttccgcacga cggttgtcag agagctccac
    11521 tccgaagagg attttattga tatcgctcag tggatcaacg gctgcagctc ctattttctt
    11581 cagtcttacc aggattctga aaacgttctc actcccggtt tttcagcctg ctccaaggaa
    11641 gagcttctgc actatctgga tattgtccgt ccctgcgcca aaaccgtcaa actgcgcgga
    11701 gtcgattaga aagccatgtc atttctaatt ccccacccgc acgtctgtat accagtatcc
    11761 aaaacagtcg tcccctgacg gctgtttttt tgacataata aaatcagaaa atccaaacat
    11821 ggacgccata tatttttcat tggaagaata atgccccggg actcccagga gatatctggg
    11881 ctccccgcta ggattttcca atctcgctaa aatcaaatac ctatagctgt agtacccgtg
    11941 gagcagaaaa ctgttattcc caaaaatcca ggcctctctg ggaagaagac cgatatcctg
    12001 gggtttgatc gtcaaaattt cacagccagg ttcatagtca aaagccagta ttttagggta
    12061 cttccgtctc agtctggccc acattctctg gtggctgcat ccgtcgtcca gctcgtgaag
    12121 aggaataaac gctctgtcgt ccgcttttat ggtagcttcc gttttgcagt cccggttaag
    12181 gcctcttgga gccgccaggt tttccgccca ctctctggcg ctcattcccc cgtccagtct
    12241 gcggcgcgaa cgcgggcggg cgcttcgccg gtctgtcctg gcttccgttc tggcttccgt
    12301 catagcgtct gttttgcctt ccgtcatagc ctctgttccg gctcctgttc cagacagcgc
    12361 atgggaagaa actgtccgga tggacggcag agtattctgg caaagcagcc tctcccgtat
    12421 actgtttttc tcctgctccc ctgcttcgtc tgtttttccc gctctttccg gcgctgtctg
    12481 tgccgcttcc acattgactc tttttgtctc ttcttctggc tcctccccct ttgcccgctt
    12541 gtttttctcc tctgtctccc gttttgtttc ttcctcttcc ttctcctgtt ctgccctgga
    12601 ctggacctct tccgctgttg ttttctcctc ttttgctgct gttttctcct cttccgcttc
    12661 tcttttctcc tcttccccct ctactttttc ctctaccggc tttatttctt cctcttcttc
    12721 ctccggcttc tccgcttctg gcttctgttc ttccttctct ggacgcccgg cctctttctc
    12781 ttgcttttcc agcgcttcct ccgcttcgct ttccggtcct atttcttctg cctggtccgc
    12841 ccgctcctct tcctgccggc tttgaagctt ttcctggctt ctgtcagcgt ttttctcctc
    12901 tttcttcacc gcctcagcag cgttcatcgc cgcatcctcc caaatggttg tgtaggaatg
    12961 gcctgcattc tccgcctcat gaatggaaag gccaaaaaac tcctgcaggg gcctgccgct
    13021 tccctctacc cgatccgcgt ttaaaagcgc gcggaattct cccgccccgt ttctggaaaa
    13081 cagcgttccg attctctgct ccccatctcc cgacagcaga tacaccccca aggggcttcc
    13141 caccggaaca acctttttta catttacagt cagacggcac tggctgtttc ttgtctccag
    13201 cttggcaaac cccacatttt tgcctttcag tccgctctca tatgtataga tatatgatat
    13261 taaccgctga taattagaca tgctatcact cctttgctat ttattgtatg caatgaagtt
    13321 tggaatctat gactgttttt aaaaagggat attcaagaac gcagaaaaac ctgaggaaaa
    13381 agacagcagc gcgccaaaag ggactggttt cgacatgaat gctccccaga agctcttccg
    13441 gaaacgaaaa aagagccttg atttctcaag actctctgta atgccgcaga ccggaatcga
    13501 accggtacga agtttaaccc tcgcaggatt ttaagtcctg tgcgtctgcc agttccgcca
    13561 ctgcggcatc tcttatgagt gatttccact ctgagaagca gcgctttcac actgcaatgg
    13621 atggaggtgg attcgaacca ccgaagcgtg tcgcaacaga tttacagtct gccccctttg
    13681 gccactcggg aacccatcca tacggtttgt aaccgtgtta gataatatca tattttgacg
    13741 aaaaaatcaa gcatatttca aaaaataatt tttacagaat tgcatgaaat ttctatttca
    13801 agcgaaaatc cggctgtatt ttcctctctg ctgtcagaac agccgcccct ctgggcggaa
    13861 gagtaatctc cagcactcca tccttcaccg ggtaaagcac ctgtccggca ttgtatccct
    13921 cctcgtaggt gagcatacag cggcgaagct ccatgctgtc tgtaatgcct gccagccaca
    13981 cgggaattct cacggcccgc tcttcttccg aggtgttgac aatcgtcact ccgcggctct
    14041 ctctctgccg cttcatctcg ccgttttcca gctctgcttt tccggcggtc cagccctccg
    14101 acacacgggc ataggcaatc aaatcctgtt cagccagaag gcgttttaca gaacctgtgc
    14161 aaaaggcagg gtggcgtctg tgaatcctgg tcatataccg gtgaaattct atcagctcct
    14221 gatcctcccg gccccagggg taggttctcc tgcagtccgg atccgtccag ccgcagagtc
    14281 ctgtctcgtc tccatagtac agcgtgggcg cccccggcca ggtcatcagc atcacaacgc
    14341 cctgtctgaa cgtgccatag ctgattccct ccgaagccgc ctcagatcca gccgaatcca
    14401 gccgccctgt cctgcggttc gtcctggtca taaaccggga atggtcatgg ttggaaagct
    14461 cgttcatagc gctgtaaaca gactggggct gcatccggca catgtggtag cgcatgatgt
    14521 caaaaaaggt cgttccattt cccagaagct tctcgttaaa ctcgtcgctg tgcttttcca
    14581 tccctgtcag gaaccaggaa accggctcca taaacgcatc gtagttcata accgtatccc
    14641 actggcttcc gtccagccag ggagacggat ctccgtagtg ctctgctaaa atcaccgcct
    14701 gagggttggc cttttttacc gcatcccgga accgctgcca gaaccggtgg ttgaactcgc
    14761 tgctgcgccc caggtcagcc gccacgtcga gacgccaccc atccgctcca aaaggcggag
    14821 agacccattt ctcagccacc cgcatcaccg cctggcacag ctcctccgac tcctcatagt
    14881 tcagcttcgg aagcgtggaa aagccccacc agccgtcgta gctgtcgtta aagggccagc
    14941 cgtcctgatt gttaaactta aaatagctgc ggtaggggct gtcagccgac acataggccc
    15001 ccggctcata attgccctca tgctgataaa tcagctccgc gtccatccac ttgttaaaag
    15061 agccgcagtg gttgaacact ccatcgatta taacccggat tcctttctgg tgggccgcta
    15121 cgataaacgc tgcgaaaaac tcatcgctgg cctttaagtt ggcctcgtca gccgtcctgg
    15181 ccgcgtattt tcccgccata tcattgtcca tggcgtcgga agccaccaga agatccatat
    15241 cctcctcgat cactccatag tggggatcaa tgtgttcata atcctggcag tcatacttgt
    15301 ggttggaggg cgacacaaag acgggattca gataaataca ctccaccccc aggcttttca
    15361 ggtagtcaag cttatcccag actccctgta aatcgccccc gtaaaagcgc cccacatcca
    15421 gcgtcccggg aagctcgtcc cagtcttcca cccgctgcac cgggcttcct atataaatat
    15481 attcgttggt ctccacatca ttggtgggat ctccgttgcg gaaacgatcc acataaatct
    15541 ggtacatgac ggctccctgc acccactccg gcacatggaa ccccggaata atccggaacg
    15601 cataggcggc ctccgcctga ttctccgctc ccagacggtt gtaaaagcag atttcactgc
    15661 ccaggcgtat ctcaaaatag taggaaaccg gttcctcgtc gatctccacg cagatttcgt
    15721 agtagtcaaa gcagccctct gtgcagatcc gcttcattct ccttcggatt ttcgtctccg
    15781 gttctatata aaaaacagaa tccgcattgt ccctggccgt ccgcagtctc agacagactg
    15841 tatccccggc gtcaggctca tagggattcc tgtaatcctt tgtttcatcg caaaacagcg
    15901 cttctctgtc aatcacactt atcactccct cgccttcttc ttttattcta tctgattttc
    15961 agatattgca caagaagaac agaatatctc ccgtcttttc agccatgttt ccggaaaagt
    16021 aaaaaggcca gcggggtaag ctggcctttt taggagaagg tatttcgttt ttatggggtg
    16081 tagcaaaaac tatataatgt attggggggg ttacgtctat tataatagca tagggcgaaa
    16141 aataagtgtg cacaaacatg aatcaatttc aaatattttt ttgtgcataa cgcggacacc
    16201 cctcttttcc cctgctgcgc gccccctcca tttcgcacaa aagcccggac ctggctttcg
    16261 ccgtccgggc ttttcaggca ttttatacct cgtgggctgc gcgtcctttt aattctctgt
    16321 ctggccgtct gttccattct ctatccggtt aaacagctcc tcaaattctg cctgccctat
    16381 cttttctctt tctaaaagca gctggctgca ctggctgagc acctctttat ggcttaagat
    16441 aatctccttc gccttctgat agcactcgtc aatgatccgc ttgatctcct ggtcaatggc
    16501 cgccgccaca tcctcgccgt aggttctggc gtgggccaga tctcttccga taaagacctc
    16561 gttctcattg cttccatagt caatcatgcc gatccgctcg gacatgccgt actcggtcac
    16621 catagctctg gcaatggccg tggcctgcct gatatcctgg gacgcgcctg ccgtgatatc
    16681 gtcaaaggcc agctcctctg caattcgtcc gcccagagaa accatgatct gctgcagcat
    16741 tcgtcccttg gtaatatact gctcgtcgct ttccggaagc ggcatagtat agccgcctgc
    16801 ccccgttccc gtcggaatga tggaaaccgt gtgcaccggg cccacgtcag gaagcacatg
    16861 gaataaaatc gcatgccccg tctcgtggaa cgccgtaatt ttcctgtcct tctcagacat
    16921 gacgcggctc tttttctccg tgccgattcc cactttaata aaggcccggt caatgtcgct
    16981 ctgcatcaga tacttcctgc cttctctggc agcgtggatg gctgcctcgt tcatcaggtt
    17041 ttccagatcc gccccggtga agccggaggt cgtctgcgcc acccggtgaa gatccacgtc
    17101 ctctcccagg ggtttcatcc tggtatgaac cgccagaatc tcctcccggc ccttcacgtc
    17161 cggtcttccc actaccacct tgcggtcaaa tcgtcccggc cttaaaatag ccggatccag
    17221 aatgtccacc cggttggtag ccgccatcac gataattccc tcgttgactc caaagccgtc
    17281 catctccacc aggagctgat ttaaggtctg ctccctctcg tcgtggccgc cgcccatacc
    17341 agttcctctc tggcgggcta ccgcgtcgat ctcgtcaata aacacgatgc agggggcgtt
    17401 tttcttggcc tcctcaaaca tgtcgcggac acgggacgcg ccgacgccca catacatctc
    17461 cacgaagtcc gatccggaaa tggagaagaa aggcaccttc gcctccccgg ccaccgcctt
    17521 ggcaagcagg gtttttccgg ttcccggagg tcccaccaga atcactccct tgggaattct
    17581 ggctcccact cccgtatatt tctgaggatc cttcaggaaa tctacgatct cctccagctc
    17641 ctccttctcc tcgctcaggc ctgctacgtt agcgaacgtc accttgctgt ctcggctcat
    17701 cctggctcgg cttctgccga aattcatcat cttggcattg cctcctccgg cgttcctcag
    17761 attcataaac atgaaaaacg ctgccagaag tcccgccgac agaagaatcg gaagcataat
    17821 cgtcagagca taattctcct tgggtatttc ctctacctcg tagggaatgc catcgtccct
    17881 gaactcctct gcaaagtctg aaacgttcag gacgtggacc tcctccatat ctcccgattt
    17941 cagccagagc tgaagctttc ccgtgctgtt ctctgcgtca gggcggatcc gtgccttggt
    18001 aatggttcca ttttccaggg ccacatagac gtcctgctcc gtcatggcag gcgcggtcag
    18061 cgggttattc ggcgatctca tccacatcac aacaagcatg gtcagggcca gtaccaggag
    18121 gaaaaatcct cctcccattg gctgtcgctg tttcaacggt tttcctcctt atacttccac
    18181 cacaccgata tacggcagat ttctatactt ctgatcatag tccagtccgt agcccactac
    18241 gaactcgtcc ggaatcgtaa agcaggtgta tttcacctga acctgcttct tcaccctgcg
    18301 ctccggcttg tccaacaggg tgcacagctc gatgctcttc gggttgcgct gctttaatac
    18361 ctcgatcagg taggccaggg tacggccgga gtcaatgata tcctccacaa tgataacatc
    18421 ctttccctct aacggctcgt ccagatcctt gacaatcttc acaataccgc tggactctgt
    18481 gccggatccg tagctggaca cggacatgaa atccagggaa acggacaggt caagacgctt
    18541 tgccagctcg caggtaaaga acacgcctcc ctttaaaatg cagatcagat gaacgggacg
    18601 tccctcgtaa tctttgttaa tctgagcagc tacctcgctg atccttttat ttacttcttc
    18661 ttctgttaat aaaacacgga tattgtcagc cacagttgat acctccatct acttgtactt
    18721 ttaaaattct ctctgtctcc tccgttacct tgtaatactc gctgatgcgc ccgcctatta
    18781 cccataacac atggcttccc tcggccaaaa gcggaatatg gctcctctct tctctgggga
    18841 ttttctcgtc aataaacagg gatttcaggc tttttctgcc gccccccttc agggtaatgt
    18901 aatcgccggg aaggcggtat ctgacagata acgtatcttt tattttatca tagtcaaacc
    18961 atttcgtata caggtttttg ggaatttccc cctggttttc cctgtccgcc acttccataa
    19021 aaagggaggg aagaccagat tcgtctcttt tttctgtctg ccccggctga agcttcgcga
    19081 gaatcagcct gtcatagctg cgctctgccc gaagaccgcc aggcagatcg cttcccgccc
    19141 cggttcttcc cctcaaaagg gccaggaccg attcaatatg cccggatgtg acatctctga
    19201 gaggccattt tttcctctta aatactgccc gcaccgcgta ggacgcctca atgtgggaga
    19261 gttccagaag gccggagaca gaaagggccg cgctctctga gccctgctct ttcgtttctc
    19321 ctgtttccaa agcctctgtt tccaggagcg tctccagcat acgttccgct ctctcctcaa
    19381 agaaacgatc cgcctccccg atcagttctc ctgcccttct gatgtgatcc gccgccccct
    19441 ggttgatctc ctgaactgcc atgggaagaa tctggtttct gattttattt ctggcataat
    19501 cgttttccag attggtggaa tccgtcacaa agggaagtcc tttctcctcc agataagcta
    19561 tgatttctct gcgctctgcg cagagcaggg gacggataat atttccccgc gccggaggga
    19621 ttccagacag gcctttcagg ccgctgccgc gaaagagctg gtagaggatc gtctccgcgc
    19681 tgtcgtcccc gtgatgggcc acggcaatct taaccgattc tggctggctg ccggccggct
    19741 ccgctgtttt ctccctccta agctcctgtt cccaccgccc ggcctcccgt tcaaatacct
    19801 ggtaccgaag aatccggccg gcctcctcct cggatatccg cctttttccc gcctcctcct
    19861 tcacattcac aaacgccagt gaaaaaggga cgccaaggct gcggcacagc tcccttgaaa
    19921 acgccgcgtc cctgtctgcc tcttcgcctc tgagaccgtg atggacatgg acggcccgca
    19981 gctccagact gtattcctcc cgaagatccg caagcaggct caaaaggcac acggaatcgg
    20041 ctccgcctga cagtccggct actacccgct gccccggcgc cagcatgttg tgagtcctga
    20101 tataggacag taccttctct ttgagactca tcgccctgtt cctcctttgt attgtttccc
    20161 cgcaggttct atttttcaaa aattccgccc accagcaccg tcatatcgtc tgcaggctgt
    20221 tcggaaaagg acatggcgaa gcttaaaatc tcgtctgcca tatcctgggg atttcccggt
    20281 tccagctcct ctaaatactg gcggaaggtt tcctccttct cctccccggg aagcgcctcc
    20341 aaaacgccgt cgctgaccat gatgacccta tcattgtccc acagctttct ggagacaagg
    20401 gccggctcca caggattcat cactcccatc ggcacgctgc ccggctcaat catctccacc
    20461 ccttcccgcc ccatgagaaa ggttcccacc gcccccagct tcatgctctc cagtacgcct
    20521 gtacataggt cgacacagca cagatcaagg gtagccggat tctgttccat gccagccagc
    20581 agaagaaccg tattcaccag ctttagcgcc gccctggcgg aaaatcccgt ctccagaagc
    20641 tgttctgtca gctccaccac tctggcgctg tcagccagag ccgccgcccc gctgcccatg
    20701 ccgtcggaca ggctcataat catctggcgg ggaagtccct cgctgaaggt gaagctgtcc
    20761 ccggaagtca cctctccgcc ccgcacggct cttgccacac cgtggatcat ctggtatttc
    20821 ccctcctcaa caaaccggaa ggtgtctgtc cgcctggtga caatgctctt cgtatccctg
    20881 gaaacgctcc accggcgtcc tcccgccgcc ctggacagga tatccgaggc atccctggag
    20941 gtaacacatt tcccgcctac ggtccgcatg gtgagatagg cctccttctg atcgttttcg
    21001 tactccagca tcagcatatt ttccaccttc atatggcggc ggcggaagag atatctgacg
    21061 gaatcctcat acgtttccgt cacatccagg gcccgttcca tctggccgga aaactcctct
    21121 aaaatagacg ccatttcccg aaactgcaca atcaccgcgt cccggctctc cagaaacctg
    21181 tttttccagg tgagattcat ggtggcccgt cccagattcc ggttcagctg gctcagatac
    21241 tcctcctgcc tgcggcagga ttcatgaaac aggcggggca tgtcctcttt gtccaccttt
    21301 cccttctgct caaaggcgcg aagcagataa tacaggtaat agctgccttc cttttttccc
    21361 gtttcataca ggttgcagcg gctgcagcct ccgcacacca tagaagccgc cgtctgcatg
    21421 gccgccagcc cctcgtcgaa gctcagcctt ttgtcggatc ccgcttcctc cgtaaaggcc
    21481 ctggccagcc cgctcagaga gcaggccatt tcccgcagcc gcctggctgt gtagacgttg
    21541 acctctgcca tatctctatg taatttcttt ccaatcataa aaatccctcc tgacctgcgt
    21601 aagcttcatt atatacaggc cggagggaaa tatttgtcaa atcaggggcg gtttctgaaa
    21661 aactttccga cagaattccc ctctactttt ccggtttcag gagaatttcg tccttgttta
    21721 ccagtcccag cttttccttg gcaactttct caatgtattc ttttgtctga acgtagatcc
    21781 ggtactcttc cagttcctgg gcccgctgct cctcctcgct tttctgcttc tccagctgct
    21841 cctccttcag acggtactgg agatccttct cctccatgga aatgccgctc agatgaaccg
    21901 taaccgccag gctcagcact accagagtaa ttcccataag cgccagacgg ttggccgctt
    21961 tttctttctt cttttttcct gccgttctat cctgcctgcg catatggcca tctccccttt
    22021 tactgtttac ttccttttca ttttaaaata tttttttaac tttttcaata gggtgaacag
    22081 aagatggctg gccgttttat cataaaaaac cattccaatc agcacagaag caatcatata
    22141 aacccgcatt tccccctcgt tcctgctgcg gagcaggaaa aaaacggaca gcccggctcc
    22201 aatccagtaa agcaaatcct ccaggcctgt ccaaatggga gcgtggctga caaacaggcg
    22261 gaacagacgg agcccgtcgt aaaccagcat caaagtcatt cccgccgtca gagcggccgc
    22321 catacaggac cattctgtgt atattgtatc cataataggc cgcctactta aacagacggg
    22381 caaagagcga ttctccctgc ttcctgtagg tctcgttgga ggagtaaacc aggctgtcca
    22441 ccgttccctc tatgtcaacc tcgccctttt ccagcgtcag gcggctcaca tgaagacctt
    22501 tccccttgac tgtcagaagt cccatatccg tatccagcac aatctggttt tcatcaaaag
    22561 ccacaacgtc ctgaatccct gtgacgctcc ccgtcccccg gttcatcaaa tccagatggt
    22621 gggggcggcg gctgattttt tcttccattt aaaaaacctc ctgacatatt taactactgt
    22681 taaatatatt aggaggtttg tctctttatg ctataaatag cggtaaagtt ccttcgcgtc
    22741 gtccttgcgc accgtctctg ccacgtccag cacctcaacc tttacagatt tgacgccgaa
    22801 ctgaatctcg atgatatcgc ctgtcttcac agcataggac gccttcaccg gctttccgcc
    22861 taccagaacg cggcctgcgt cgcacgcctc gttggccact gttctgcgct taatcagacg
    22921 cgaaaccttt aaaaatttat ctaatctcat gtgattatgc gtttaccata tcctttaatg
    22981 cttttccagc cttaaacttt ggtgtcttgg aagctgcgat aggcatagtc tcgcctgtct
    23041 tcgggtttct tccctctctt gccgctctct cagaaacttc aaatgtacca aaaccaacta
    23101 actggatctt gccgcctttt actaactcct cagaaacagc ctctgtgaaa gccttgattg
    23161 ccttctcagc gtccttcttg gaaatctctg ccttctcggc tacagctgca attaactctg
    23221 tcttgttcat tgatttattc ctcctgcttc ttcttatact gagcttctac ttgccatgaa
    23281 gcctgaacgg ccaaaacagc aatattactc cttcaaaaac cgctaattac ttaccttaca
    23341 tttatataca tttatacctg ctttgtcaag ttgttttatg gttttttgcc ttttccgccc
    23401 gttttatccg ctcccataaa tctccctcgt ttccgtctgt ttccggaagg tctccgccga
    23461 agattttcgg atgcctgcgg accattttcc ggctgattcc gtccaccgcg tcctcgaagg
    23521 caaaaagccc ctgctcctct gccatctggc agtagaacac cacctggaac agcagatcgc
    23581 ccagctcctc gcagagattc tctgtgtcct ggtttctgac ggcctccgtc acctccccgg
    23641 cttcctccag aacgcaggaa accatggtct caaaggtctg ctttctgtcc cagggacagc
    23701 cctcgtctga acggagaatg cggaggatgt ttctcaagtc ctccagcgtg taggcgtccg
    23761 ggcggtctgc cccataaaac tgcttcaatg actgtatatt ttctgtttcc ttcccgttca
    23821 tttctcgtcc tccttccgtt tttttcggca atgattttat tatagtataa atctctgttc
    23881 ttttctcata ctttctcata ctattttcaa aaaataaaag cgtatcccat ggaggaaata
    23941 acagctgaaa aagccttctt ttgtgttgac agcgtatctt tcagaatatt gtaatataag
    24001 tacagaaaat tgtacgtttt attcttagag tagggaattc tatgctggca gttaattata
    24061 cagaattaag aggtcatatg aaaaatatgc atcttatggg gaaccaacta taaatggctt
    24121 atggagtcca aaaaacagct ggaagacggt ttctgtcagg taaaagagct catcgaggtt
    24181 gctgcggatg aataaagtgt ttacccaaaa cggccagact gattacgtct actggcagac
    24241 cgaggacaaa aaaactaaaa aaaaatcaac aaactcattg aagatatctg cagaaacgga
    24301 aattccagtt taggaaaacc cgaaccgctg ttaggcgggt taaccggatt ttggagccgg
    24361 agaattaacg aaaaagacag gctggtttat aaaatagatg aacagaatgt atacattatt
    24421 tcatgcagat atcattacgc agatcactaa taaaaatgta taaaatccct ccatctgcag
    24481 atactatttc cagaaatgat gatatcagga aaagcgatgt taaatggagg aattttttat
    24541 atgaaagcga ctggaattgt aagaagaatc gacgatttag ggcgggttgt catccccaag
    24601 gaaatacggc ggactctgcg tcttcgcgaa gggacacctc tggagatatt cacagatcgg
    24661 gagggagaaa ttatcctgaa aaaatactct cccatgatgg aactgaccgc cttctcctcc
    24721 cagtatgcag aggctatggc ccagagtacc ggcctgatgg tctgcatcac agacagggat
    24781 caggtcatcg ccgtgtcagg cggccccaga aaggactatc tgcagaaatc tatcagccgc
    24841 cagctggagg gcctgatcgg ggaacggcag attgtgacgg caggcaaaga cgatagaggc
    24901 tttattcccc ttaccccgga cgagccggag ggagccactg cgcaggtcat cgtgccaatt
    24961 atctgcgagg gagacgccat cggctccgtc atccttataa gccgggagcc gcgggtaaaa
    25021 ttttcagaga cagagctgaa gctggcctcc acagccgccg gattcctggg aaggcagatg
    25081 gaaggataac atcaattcac agcatcaaat cgggacggtt tccattgttc aaaccgcccc
    25141 tttttgtctc ttcttagctc ttcttccgct aatccccgat cataattttt ataatggtat
    25201 cgttggtggc ccgcattccc tctctggcca ctcttcctgt gttgctgatg gtctcgtccg
    25261 cgtcctcccc gacgattccg tcgccgcaga ggaacttctc tccctccgcg ttcatgcggc
    25321 agcccatgat tcccgcctcc acagccatgg cgatctttcc cgcgcaggac ggcttggctc
    25381 cgtcgcagat catgcctgga gtgacggcca gagtgttgct gacagtccgg catacggcct
    25441 cgaaatctcc gccctttaag taggcaattc ccgctcctgc cccggccccc gcgctgacgg
    25501 ctccgcagaa agcagacaga cggccgatgg gcgttttctg gtaaattgcc gttaaattgg
    25561 acagggctaa ggcccggtag gtcttctcct ccccggcgtg caggcggtcc gcatacacca
    25621 gaaccggcac ggaaacggtg attccctgat ttccgcttcc agagttaatc acaaccggca
    25681 gctcgcagcc gtccattctg gcgtcggatc cggccgccgc catcgccctg gccagaatcg
    25741 agatatctgt atcagaatca gcctcccggc tttccacgca ggaagccagg ctttttccca
    25801 cattggctcc gtaggaatgc gtcattccct ctttggcaat cgccatgtta tagctggcct
    25861 ggcgctttaa aacctgcttt aaatcatcta agtctgccgt attaataaaa tcccagattc
    25921 cctccataga aaggcaggag cggtctgtca gccccttctc cgactctccc tctaccttta
    25981 cttctttttt taccacgcca tttttctcaa tcagaaccac atttgtatgg taattggcga
    26041 tccgtactct ggaccagtcc tctcctttat acatggtaat cagaatctca aacatgaggc
    26101 cgttgtcaat gtgctctacc cgaatatccg tccgatccag aaactccctg atctccttga
    26161 tctgctcctc agatacctgg gaaatcactt ccagctcctt ctttgcgtct ccagccacaa
    26221 ttcctgctgc cgccgccgcc gcgatcccct tcatatggcc tgtgttgggg acaatcacgg
    26281 atttgacatt tttaagaata cttccgctga cgcctaccac cacccggtcg ggaagcgcgc
    26341 ccagctcctg tctggccaca gccgccccat aagccagggc aatgggctcc gtacatccca
    26401 tagccggaat cagctcctcc ttcaaaatat tcatgtaagc ctgatatctg ctgtctgtcc
    26461 gttccatact tccttccctc tttccttttt ctgccttaaa tttttaatca tctgcggcca
    26521 attttcacgc ccctaaaaga gcagaaaagt tttcctgcga ctaagctttt ggtggagcat
    26581 ggaaaacttt tcctgctctt ttaataacgc gtaaaaactt tccgcttccc ctcttcttga
    26641 tctcttctta aaactattat agtatagagc tattagaatg taaaatttaa ggttttaaag
    26701 aaatcgttta atatttttaa atcaaatagg agcgcatatg gaatttcggg agattgccac
    26761 ctttctgcag gcggcgcagc tgaaaagctt ctcaaaggca gccaaaaaac tgaattattc
    26821 ccaggggacc gtgactatcc aaatcaaaaa cctggaggag gagctgggcg tccgcctctt
    26881 tgaccgaatc ggcaagcaga tcagtctgac cagccgcggc gaacagttct atcagtacgc
    26941 tgtcactctg atgaaaaata tggaggagat caaatgctcc ctctctgaca gcagggaatt
    27001 gacgggcagc ctggctctgg gaaccatcga atccctctgc tcctccctgc ttccgcccat
    27061 tctctccgaa taccaccggc gttttcccaa agtgaatgtc agcgtcgtga tcgactcccc
    27121 cagagtgctg ttagacaggc tcaacgacaa ttctctggat attgtatact ttcttgacaa
    27181 gagaatttct gatccgcggt ggattaaggt actggaagaa ccggaggaca ttgtattcgc
    27241 agcttcgtct ctccacccgc tggcaggccg atccggcctt aaactggacg aaatcatttc
    27301 ccaccccttt ctgctcacag aaaaagcagc cagctaccgt catattttag atcagtatct
    27361 ggctgcctat ggaaagcaga tccgtccctt tctggaaatt ggaaatacgg acttcatcgt
    27421 ccatatgctg cgggaaaatg caggcgtctc cctgcttccc ttcttttctg tccgccgcga
    27481 tattgaaaag gggcgtctgg ccgctctgga cgcagaggat tttcatatgc aggtctggcg
    27541 tcagatcgta taccacaagg ataaatggat caccggagag atggcggaat ttttaaagct
    27601 ggcgggggca aagccagtct gacgcgcaaa aaccgacgtt ctgtcaagcg ccctggaaac
    27661 agtctcagag acgctttaaa aacgccggtt cttctctatt atggccttct gcccagatac
    27721 ggcaggaagc gaaacgcgcc ctgatcctct gagcagaatt ccgatttcac tctaagcctg
    27781 ccctgcagct ccgtcctcgt ccagcccgct ggccgtggcc tggtatttct ccagaacaat
    27841 gctctgaatc atatccctgg tctcagaatt aatcggatgg gcaatatccc tgtattcgcc
    27901 gtccgtagac ctgcggctcg gcatggcgat aaaaagaccc ttctctccgt cgatcacctt
    27961 aatatcatgg actacaaatt cattgtccag ggtaatcgac acaatggcct tcattcttcc
    28021 ttctctctca atccgtctga ctctcacgtc tgtaatctgc ataacataac ccctcttccg
    28081 tactgcccgg ttctggaccg ctctttcccc ttgtgccgtc cctataaagt gaaacgctcg
    28141 tttttctcga taacgatctt cacgttatcc ggcgctccga tgtgcgtcgt gttggcccgg
    28201 atggtgtccc ggctctccac aatgcagttt tcaatcactg tattgtcgcc aatgtaaacg
    28261 tcgttcaaga taatagaatt tttaatcacg cagttgttgc cgatgtaaac ctttttaaag
    28321 agaacggaat tctccacgct tccgtttaaa atacagccgc tggaaacaag actgttcttc
    28381 acctcagctc caggattgta cttggccggc ggcaggtcgt ccaccttgga gtaaatctcc
    28441 ggatattcgc ggaagaagta gtgtcttacc tcaggcttta aaaagtccat attggtctta
    28501 tagtaggaat ctacggaggc gatgttgctc cagtaggaat ccagcttgta tgcgtaaatg
    28561 cgcttcaggt tcttataacg caccagaata tccgttacaa agtcatatct gtcctcggaa
    28621 gcacagcgct ctaaaagctc aatgagctgg cggcggcgga tcacgtagat accgcaggaa
    28681 atcgtgttgg aggtagctaa catcggcttc tcctcgaagt cggtaatacg gccctcggcg
    28741 ttggtcttaa ccagtccgaa gcgggttacg tccgcctccg gctccatatc cttgcacaca
    28801 acggtgatat cggccttctt ctcaatgtga tactccagca ccttgtggta atccagcttg
    28861 tagatgcagt ctccgcctgc gatgactaca taaggctcat ggctcttctt taagaaatcc
    28921 aggttctgat agagagcgtc cgccgttcct ctgtaccagt cgctgtgctc tgccgtgatg
    28981 gtaggagtga agacgtacat gcctccctgt tttcttccga aatcccacca tttggaggag
    29041 cttaaatgct cgtttaagga gcgggagttg tactgagtca gcactgccac gctctgaatg
    29101 tgggaattgc tcatgttgct gagtacaaag tcaacgctcc ggaagcttcc tgccaccggc
    29161 atagcggcga ttgccctctt gttggataac tctctcattc tcttgctgtt tccgcctgct
    29221 aaaacaatac cgatcgctct cattgtactc cacctgcctt tataatatag tctccgcttt
    29281 caagcgctcc gtcgtggtaa tccgcactct ctgtcactcc ggaaacagcg gtatttcttc
    29341 ccaccttcac tccgtccgga atcacagaac gctctccaat ggtaaccaga tcgaactggt
    29401 aaacctttgg atcatatttg ctgggcgcgt actcgcccac accgatctcc gcattggctc
    29461 caatggccac atcctcggcg ataatggcct tgtccaccac cgtgccgtcg ccgatggagg
    29521 ttcccttcat tacaatggaa tccttcacca ccgcgccctt tccgacggtc actccggctc
    29581 cgatgacaga attgataacc tggccgtaaa tctctgagcc ctctccgata atacttctct
    29641 cgatcttcga atcaggcgcc gtatactgag gcggaataat gtcgctcttc gtatagatct
    29701 tccagtactc ctcatacagg ttgaattccg ggatgatgtc gatcagctcc atgtttgcct
    29761 cccagtagga gcccagagtt cccacatcct tccagtatcc gttatactcg taggcgaaaa
    29821 ctctctttcc gccggaaaag cagtaaggga tgacgtgttt tccgaagtcg cagcccggct
    29881 cctcagagag cttgattaat gcgtcccgca gcaccggcca gctgaatatg tagataccca
    29941 tggaagccag gttgcttctc gggttcgtag gtttttcttc aaattctgta atacggtttt
    30001 tctcatctgt gatcaggatt ccaaaacggc ttgcttcttc aatcggtaca ggcatggctg
    30061 cgattgtgat atctgcattg tttgccttgt gatattccag cattacctcg tagtccatct
    30121 tataaatgtg atcgccggaa agaatcagga catagtccgg attatagttc tccatgtact
    30181 ccaggttctg gtaaatagcg ttggccgtac ctgtgtacca gtcgcttccc ttacttctct
    30241 cgtacggcgg aaggacggta acgcctccca cgttgcgatc aagatcccac ggaattccaa
    30301 ttccgatatg cgcgtttaag cgcagcggct gatactgggt cagaactccc actgtatcta
    30361 cgcctgaatt aatgcagttg ctcagaggaa agtcgataat tctgtacttc ccgccaaaag
    30421 aaactgccgg cttcgccact ttctgtgtca gcacgccgag acggctgccc tgtcctcctg
    30481 ctaaaagcat agctatcatt tcttttttga tcacgatatc accccttgat gtatatttgc
    30541 ttgtgtgctt taatgttgta acgcttatta tatcatactt tttataaaaa gtacacaaat
    30601 taccgaatga ttttatctat tttttgtaca ttttccgaca ttttgtatgt catatcgcca
    30661 gaaaacacca aattcaactg catcttgtgt ttttcagcgt ttccgccttc cctcccatgc
    30721 gtaaaaatac tgctcttccc cttgaatatg caggaaaaat acagtataat ggcaacatca
    30781 gaaatttgtt tgaaaatagt caaacaaagt acctgtttca tttcgaaacc atttgacggc
    30841 tcgggcctcc tatctgcgcc cgggccgttt atcaaacaaa aaggagcacg attatggatt
    30901 tgattaccgt aagagagatt tacagggaca gagacaaatt ccttggaaag gaaatccaga
    30961 ttggcggatg ggtgagaagc atccgcgatt ctaagacttt tggatttatt gtagtaagcg
    31021 acggaagcta ctttgacacg cttcaggtgg tttaccatga caatatggag aactttaacg
    31081 agatcagcag gttaaacgta ggcgccgcca tcctggtaaa gggaactctg gtagctactc
    31141 ccgaggccaa gcagcccttc gagattcagg cggacgaggt tatcgtagag ggcgcgtcct
    31201 ctcctgacta tccgcttcag aagaagcgcc acagccttga gtatctgaga accatttccc
    31261 atctgcgtcc cagaacgaac accttccagg ctgtcttccg cgtgcgctcc ctgattgcct
    31321 acgcgatcca tcagtatttc caggagagag atttcgttta cgttcacact ccgctgatca
    31381 caggaagcga ctgcgaggga gccggagaga tgttccaggt aactaccatg gatttaaaca
    31441 gcgttccgaa gacagaagac ggcaaggtgg atttctccca ggacttcttc ggcaggccta
    31501 cgaacctgac tgtaagcggc cagttaaacg gcgagaccta cgctatggcc ttccgcaaca
    31561 tctacacctt cggaccgacc ttccgcgccg agaactccaa caccacacgc catgcggctg
    31621 agttctggat gatcgagccg gagatggcct tcgcagactt aaacgacaac atggctctgg
    31681 ctgagagcat gttaaaatat gtgatccgct atgtgctgga gcacgcgccg gaggagatga
    31741 actttttcaa ccagttcatt gacaagggac tgttagaccg tctgaaccat gtgttaaact
    31801 ctgaattcgg ccacgtaacc tacacagagg ccgtgaagct cttagaggag cacaacgacg
    31861 agttcgacta caaggtattc tggggctgcg atctgcagac agagcacgag cgctacctga
    31921 cggagaagat cttcaagcgc cctgttttcg ttaccgatta tccgaaggag atcaaagcct
    31981 tctacatgaa gatgaacgag gacggcaaga cggtagccgc catggactgc ctggttccag
    32041 gaatcggcga gatcatcggc ggaagccaga gagaggacga ctacgacaaa ctggttggcc
    32101 gcatggagga gctgggactt aagaaagagg actacggctt ctacctggat ctgagaaagt
    32161 acggctctgt gcgtcattcc ggcttcggtc tgggctttga gcgctgcgta atgtacctga
    32221 caggcatggg caatatccgc gacgtgattc cgttcccaag aaccgtaaac aactgcgaat
    32281 tataagaagc agccacagga attaaaacga ttcagttgac ataacacaac acgatgaggg
    32341 catctcaaag acggcggcac gccttccctg aggcgccctt ttcttctgaa tgaaaggatc
    32401 ctgctcttct gccggatcct atttcagaag ctgtcttaga gagggggaat aaggccttga
    32461 aatttattca taccggagac gtccactggg gcatggcccc tgacagcgat aagccctgga
    32521 gcagagagcg ggccagagat atccgcgaaa ccttcgccgc cattatcggg aaggccggtg
    32581 agctttccgt ggactttctc tttatcgccg gggatctgtt ccaccggcag ccgcttttaa
    32641 aggatttaaa ggaggtcaac tacctgtttt ccaccattcc ggacgtgcgg atcgtgatga
    32701 tcgccggaaa ccacgaccgg gtgcggaaaa gctccgctgt cctgagcttt aactgggcac
    32761 ccaacgtcac tttcctgtcg gacgaggaat tttcttccgc ctacttcgag gaactgcaca
    32821 cagaggtgac gggcttttcc tactggacct ctgagatatc agaagccagg ttaaatgata
    32881 tctcggctcc cgacgacggg ctcatccaca tccttttagg ccacggaggc gacgcgaaac
    32941 acgtgcctat tgataaggaa gggcttctta aatcaggctt ttcctacgct gccctggggc
    33001 atatccacaa gcctgagatc tcccagagcc tgagaatggc ctggtgcggc tctccggagc
    33061 ccctggacaa gacggagacg ggacgccacg gcattatcta tggggaaatc agtgaaacca
    33121 gccttcggat taccaacctg gagtttattc ccatggcaaa gcttcagtac attccgctca
    33181 tggtcaatgt gacgcccaac accaccaaca cagagctgtt cctgcgaatg tcccaggaaa
    33241 tcgaaaaacg cgggtctgaa aatattttcc gttttcgctt aaaaggcatg agggatcctg
    33301 atatttcctt tgatttagaa tctttgatga tgcggtacag aattgctgat atcttagatg
    33361 aatcagagcc tcagtacgat ttcagcgccc tgtttgagga acactcaagc gatatgatcg
    33421 gtttctatat cagagcgctt cagaagccgg atatgagccc tgtagaaaaa aaggctctct
    33481 attatggcat ccacgccctg ctgctcacta cggatgaaag gagttaaacc atgcgttttc
    33541 tggatcttta tattaaaggc tttggaaaat tccacgacac ttttgtctcc tttgaagacg
    33601 ggctgaatct ggtttacgga aaaaacgaag ccgggaagtc caccattcac acctttatcc
    33661 gcggtatgct gttcggcatt gagcggcaga gggggcgggc ggcaaaaaac gatctttaca
    33721 gcaaatatga gccctgggaa aacagctcca cctatgaggg acagctgcgt ctggaatccg
    33781 gcggcactat ttaccggttc gagcggagtt tccagaaaaa taagaaggaa tttatcattg
    33841 tcaatgaaac tacaggccgg gaagcagagc ctacaaaggc tctgttagat gagatcctct
    33901 gcggactcag cgaaactgcc tacaacaata ccatcagcat cggacagctg aaaagcgcca
    33961 ctgagggcgg catgatctct gagcttaaga actacattgc caatatgaac acctctggaa
    34021 atatggcttt aaacattaca aaggccactg cctatctgaa aaaccagaag cggcagtttg
    34081 aaaaccagct gacgccggag gcagccaaaa cctacacctc tcttctggga gaaattaaaa
    34141 atttagagcg ggaaatttcc tctcctgaat atgaaaatca gctgcgctcc tatgcaaaag
    34201 aacggacgga tttaaaatct gctatcgaaa agaagcagga ggagagggag gaactgcttt
    34261 gccggatcga aaagggccgt caggcactgg cagagttcga atttacagac gcccagtctg
    34321 tttctgctta cttaaatcac gccgaggata tttaccgcca gtacctggaa gcaggacagg
    34381 ccgcctcaaa gaaatcacgc cggggacttt ctgtattttt cggccttctg ggacttctgc
    34441 tgcttctggg agccggctac ttcttctgct ggggactgat gccaggcaat tccttcctgc
    34501 cctggatgcc ggaaaccatt gatcctcttc tctccggtgc tgcagctgcc ggagcgtcgg
    34561 ctgtatcctt ctttgctggg gctctgttcc gcttaaagct gcgtcaggag aaaaaaactg
    34621 cctctctgtg cgcttctaat ctgtccgaga ttttcagacg ccacctggga gacggcacta
    34681 tctctgaaaa ggccatggat gccctcagaa acagaatgga cgactttata gacctctgct
    34741 ccatgattgt ccgctccgag gaaactgtac ggcggcagat ggacgatgta gaacagctgc
    34801 aggggcgtca gaatcaatgc tctgaaatca tcgaacagca gcagcgggtt cagtgggagc
    34861 tggaaaagaa gctggaacat ctggcagagc ttaaagatca ggcctccgcc ctgcgccaga
    34921 ttatcgcaga aaatgacagg atacgggagg aaatcgcggc catcgagctg gctcaggaaa
    34981 ccatgaagga actttccatg tccatccgtg attcttttgg cctctacctg aataaaactg
    35041 cttccgagct gataagcggc attaccggcg gcctctacac cagcatgagc atcgacgaaa
    35101 atctgggagc attcttaaac accagaagaa aactgattcc tctggagcag gtcagcagcg
    35161 gcacggcaga tcagatttac ctggctctcc gcctggcggc ggcacggttt attcaaaatg
    35221 gaaccgattc catgcccctg atcttcgatg acagcttcgt gctctatgac gacgaccggc
    35281 tgcggcaggc tctgcgctgg ctgtccgagg catacaaagg gcagattatt atcttcacct
    35341 gccacagaag agagctggat atcctgaaag aggaaaaaat taagcaccat gtggtgacaa
    35401 tttgacagaa aaggtctgac aaagcaggaa agggaccggt gaaaaacagg gattactcct
    35461 ctatttttca ccgatccctt tctatgaaag cgtctattcc gccgtcacta cccacttaat
    35521 acatccgtcc ttcttgtgtt caaaggtatc gtatccctct aaaatctgag acagcggccc
    35581 tctgtgagtg atcagaaaat ctgtggtgag ctttccttcc cttaacagtt ccaaaagctc
    35641 tctgcagtcc gcagcgtcca cgccgcctgt cttgaaaatc aggtttttcc cgtacatcct
    35701 ggtcagggga agcaccggat ccttctcata catggccacc agagccacga tcccgttagg
    35761 acgggctacc tcccaggcca gagtaaagga agcctccgtt cccgccgctt ctatcacagc
    35821 gtccgctcct ctgccctctg tgaggccttt gacagcctct gcagcctctt ggcccgtcac
    35881 gctcagatat tcgcctgcca gacggttttc cctggctgtt ttcagacgtt cttcattggg
    35941 atcaatgaga atcacctggc cggctcccag atagagcgcc gactgggccg cgcacatgcc
    36001 caccgggcca gccccgatta cagccaccgt atcccccgtc tttatctcgc acagcttagc
    36061 tccccagtag ccgctggata aaatatcccc cgtaaagagc gcctgctcct ctgtcaggcc
    36121 gtctggaatc ctgtagaggc tggtgtccgc caggggcact ctcacatact ccgcctggca
    36181 gccgtctatg acgcagccta acatccatcc tccctgctcg cagttgttga caaatcccct
    36241 tctgcagtac cagcagtctc cgcagatagt ctcgcagttg gcggcagccc tgtctcccgg
    36301 ctttaaggtc ttcacctgag aaccgatctc cactacctcc cctgcaaact catggcccag
    36361 aatcacgcct tctctggctc ttggaaccgc cccgtttctg atgtgcaggt cgctggtgca
    36421 gatggtggag cgggtcaccc ggacaatggc gtctgtgggc tccttgatga ctggaaccgg
    36481 acgctcctcc agccccagct ttccaatccc ctgaaataca agggccttca tcatcttctg
    36541 ttccatttcc ttctcccggc agttttccct tccggtctac ctgccctagt ccctgattcc
    36601 cgccttatac ttctccacca ggcggttgat ccttcccgtt gggtttaaca gctcgcttaa
    36661 ggaagcgtcg tggtttaagt tgtcgataat cagggcaatg tacttgctca tgtctacgtc
    36721 gatatagtac ggtctggaga gcaaatccgc cgactggtaa atcaggtttg tagtcagcac
    36781 gcggtcaatg actccgttct cataatactc gtcaaacttc tgaagtccgt ttgtaaacag
    36841 gccgaaggta gcgcagacaa agacctttct ggcctttctc ctctttaact ccttggccac
    36901 gtcaagcatg ctctctccgg aggagatcat atcgtccaca atgatgacgt ccttgccttc
    36961 cacgctgctg cccaggaact catgggctac aattgggttt ctgccattga caatcttcgt
    37021 ataatcgcgg cgcttgtaga acatgcccat atcaagtccc agcacgttgg caaagtacac
    37081 ggcgcggcgc attccgccct cgtccgggct gatcaccatc atgtggtcgt tgtcaatctg
    37141 aagctccttc tcgtgcttta acaggtgctt gataaactga taaatcggct gaaccgtctc
    37201 aaagcccttt aacggaatcg cgttctggac tcttggatcg tgagcgtcaa aggtaatgat
    37261 gttttctacg cccatgtcca caatctcttt cagagccaga gcgcagtcta aggactcgcg
    37321 gcctgtgcgc ttgtgctggc ggctctcgta gaggaacggc ataatgacgt taattcttct
    37381 ggcttttcct cctacggcgg cgatcactct ctttaaatcc tggaaatggt cgtccgggga
    37441 catgtgattg accattccgt tcagggaata agtcagattg tgattgcata catccactaa
    37501 aatatagata tcatctccgc ggacagactc gtttaaagcg ccctttccct ctccggatcc
    37561 aaatctcggc gtgctggcgg aaataatata ggaatctctc tggtaaccgg caaaggcaat
    37621 cgtagacttg tgctcgctct cccgctctct gcgccagtct gtcagatatt tgtcaacctt
    37681 ttctcccatg gctctgcagc tcttcagggg aatcaggccc agaggcccga caggaatggt
    37741 atcaataatc ttctcttcgt acagcatgtt tctcctccca cgtgtcagtt aaatacttct
    37801 tctttatatc atttaacctg ctctgcgtca accccgccca aggagctttt tccggatccg
    37861 gatgtcctct ccgtaaaggg gaatcaccgt atactggctg ataatcctgg acatgacgcg
    37921 gtctgtaaat tcatctctca tctcgttgac cggaagattg gtggaaatga tggttccctt
    37981 cttccggttc agcctctcgt tgacgcagta gaacagctga gaggtggtaa acgtattcac
    38041 aagctctgtg cccaggtcgt cgataatcag cagatcgcag tccagaagat agctggaacg
    38101 atcccgatcc tcctccgtag cgtcatagtc aaaccgttcc tttgaaaaaa tctcgtacat
    38161 cttaactgca ggcagataga ccaccgaata tccctgatcc agaagctctt tggcgatgca
    38221 gttgcttaaa aaggtcttcc caaggcccgt ctttcccgta aagagcagat tgtccttggt
    38281 ttccccaaac ctctccacgt aggacttgca gagagccgcc acctgcttca tatattctct
    38341 ggccgtcttt ttgcttctgg gatccggttt cgtatcgtcg aaatactcat aggaaaaggt
    38401 gctgaaattc tctcttttta aaatttccct gatgttggac tgatcgtaca gaagggcaat
    38461 ctccctcttt ttaaagcagc tgcacttgcg cccgtccgca tatcccgtat cgcggcagag
    38521 gggacagtcg taatgaagct ccaggtagtc tgccggatag ccgtaggcgg ccagaagcac
    38581 ctggcgctcc tcgcacagat cggcaatctt tgccttcagc cctttcgccg ccctgtcatc
    38641 tccggccaaa agctgtctgg cgctttttac ggctgaggag gcaatctcct cgttcagctc
    38701 tttcacggca ggaattttct catagatctc ctcccgcctc ttatccagct cgtgcttctg
    38761 gcgaagctgg gcctggttgt aaatacgcat aatagaatca tactgggaat tactcagcgc
    38821 catgttttcc tcctgtgctc tctggctggc ctgggccgct tcctccgtct tcggaattga
    38881 tcatgctcca gatcatctcg tcgtaattat agccgtgctc ctccaggtta tgaaagcggt
    38941 tgttcgtccg cctcttttcc ggctggctgc cggatttccc ttccctggcc tttttctccc
    39001 gtctgagcct ggtcacgtgt tccacgtcct tcatggtccg caccccggcc cggctccagt
    39061 cagtcagaat cgtgtccgca tactggaagc tgggcttgtg gatggccgcc atggtgcggc
    39121 tgcaggcctc caccacaatc tccctggtaa agccgaaggc tccgaaccat ttgtccatca
    39181 ggtcaatctc gctgtccgcc ggatttctcc ccgacagccc gaaggccctc atcacggcga
    39241 aaatgtcctt cttatagccc atagactggg ttttcgcctc ctcagccgtc ttaaatcctc
    39301 tctcgtgcca gctcagcccc accttctcaa tatagcggat gctggtgtgg ccgttctggg
    39361 cgcaggactc caccagatac tccaaaagct ccgccggcat gtgaagctgc ccgtacaggt
    39421 aggcgaacac gtcgcagtcc gtgggcgtaa acgtcctgtt taaatatttc tgggcaatgt
    39481 agagcagctg ggaaaattcc tcgtttctcg acaggccgtt cagaactgcc cccgaagatt
    39541 tctttctgcc cggctccaga gaaggctggg acaggcggct ctctgctcct tccgcagacg
    39601 ctttttcctc cgtcttgctc tctgccgttt tactctctgc cggctttctg tccgccattt
    39661 ttctgtccgg cgccgcatcc gctgcggcca ggccagtctg cctgttgtcg cccagctcca
    39721 gaaccccctc ctgctcccag tagaccaggg cgcggcgcac gtccgcctcc gtatggttca
    39781 gggcgtcggc aatgtcggcc acgctgtccg ctctgccgcc gtttctcaaa atataaagat
    39841 aaaccttcac atattccccg ttggccctgg ccatataatt gtctataaat tcattggaga
    39901 cgacagtcac cccatgggcc agacgattcc ttatgaagtt tcccatctct tttcctcccg
    39961 ctgttttact gtaaaatcat tccttccggc gtccaccttt tatccccaga atcccgtgtg
    40021 aatattgtgg ataatgtgga caatcccttg tcctttcccc gccgtttttg tcccttcctg
    40081 tcgaaaacct tgaattttca atgtttttca tacaatagaa acttttgtta tgtcaatcaa
    40141 gaaatccaca ccagaccgct gtataaaatg ttgaaaacta tgtggataat gtggataact
    40201 atttagaaag cagctcctcg cccacagtta caatgtctcc ggcccccata gttatcaaca
    40261 aatcccctgg ctggcagttg gttttaagaa attcttcaat ttcagaaaat gtcggaaaat
    40321 accagacttt tgttccaagc ttctcaattc tttccgcaat atctctggag ctgattccca
    40381 gcgtatccgt ctctctggcc gcgtaaatat ccgccaggat cacccggtca gccatagaaa
    40441 gggcctctgc gaactcatct aaaaaggctt ttgtcctggt gtaggtgtgg ggctggaaca
    40501 cgcaccacac ctggttgtgt ggataattgc cagccgtctt taaggtagcc tgaatctcct
    40561 gaggatgatg ggcatagtcg tcgataaccg tcactccgtt gaactcgccc ttcttttcaa
    40621 agcggcgctt ggttcctgta aaattcaaaa ggcctctctt taccgcctcc atggaaacgc
    40681 cggctgtgag ggcggccgca atcgccgcga gagcgttgta tacattatgc tctcccccta
    40741 cgccaaggct tatgatatct cttcttacgc cgttttcata cagctcaaag gacggccttg
    40801 caagctcgtc gtaggtaatg gaaccggcgc tgtagctgca cgcctgatct cttcccaccg
    40861 taatgaccgt tccgctgaca tttttcacaa tctcctgcca gttttcaatc tctgcgttaa
    40921 taatgacgct tccctgagcc ggaaccttct ctgcaaaaag ggcgaaggaa cggcggatat
    40981 cggccagatc cttgaaaaag tccagatgat cctcctcaat atttaaaatc agagccatag
    41041 tggggaaaaa ctccagaaag ctgttggtgt actcgcaggc ctctgtgatg aaaaattccg
    41101 gtccgcccac ccggatattg ccgccgatag acggaagaat gccgccgaca gagatcgtgg
    41161 gatccgcctt ggctgccagg aaaatctcag acagcatgga ggtagtggtc gtctttccgt
    41221 gggttccgga tacggcgatc gcttccttat aattacgcat catctctccc aggagaaccg
    41281 ctctggacat catgggaatg cccgcctgct gcgctgcctg gaattccggg ttgtcagggt
    41341 ggatagccgc cgtgtaaact accgcgtcca ccgcgccgcc tgcctcgtca gcggccgcga
    41401 tattttccgc cctctgtccg atagacacaa aggcgcctct gcttcttaaa tgctctgtca
    41461 gctcgctttc cttggaatca gagccggaga tcgtaaatcc ctcatccatg agaatctcag
    41521 ccagaccgct catgctgatg cctccgattc ccataaaata aatgtgctgc ggtttattaa
    41581 aatcaatttg atacatagat cattccacct ttttcattaa aattattgca atgtttcttt
    41641 catttaactg cttttgcagg gaaatgtcaa ctgatacagg aaaagctgta aaagccagtc
    41701 cggcctttac agcttttcgt atcgttctaa tctctttgtc ctgccaggcg gccggaatgc
    41761 ttcttcctct gaattctatc tgagttcttc tccgtccagc cggtgaaacg cctctacgct
    41821 gcgctcactc ccctgaaaat catatgctta taacgctcca gagcgcggat taaaacgctt
    41881 cccagcactc ctacagccag aatctctccg attcccactg tcaccatagc cacaggaatc
    41941 aaatccgtgg atccgtaagc ataccgcaga atccatggaa cgatcactgc gttggaaata
    42001 atcggaggaa gcagcaccag aaaacggttt cctctgagag cgtaggagcc gactgctccg
    42061 atcagagtgg caatgcttcc aaaaatcacg tccatagtca tagcccctgc cagcagattg
    42121 gacagcaggc agccgataaa cagtcccgga accgccgccg gagtgaagta cggaagcacg
    42181 cacagcgcct ccgaaatcct gaactggacc ggtccgaagc tgatcggcat aaacatcatg
    42241 gtcaacgcaa tataaatggc cgctatggcc gcgctgtagg tcagcaggta cacagatttc
    42301 ttgtttctct cgttcatatt cagttgtctc ctttagtttt gttttacgag tggaaggtcg
    42361 cgaacactcg attcatttta cgccggaaat cggcggaaag ccctgtaaga ccttgttttt
    42421 atgggctttg caacgggtta gagtatagca tagattcggt gcgggcgcaa gaggttagtg
    42481 atatacttca cgcctacatt agtgatatac ttcacgcctg ttatccgcaa acctggctct
    42541 tcctccagaa cgcgcgccgg aaccaggggt aaaataatct aactgatttt ccttttagag
    42601 gaaccagaaa acttatcgta aatcataccg gacaatataa ggcagacaaa tactgccgtc
    42661 caaatgatcc aaaggttatt tgccggcgta cctcctgcgt cagtaccatc gctttgaaac
    42721 atgattccga ccataaatcc agccatatat gaaaaggcag tacaaacagg cgatattttc
    42781 ccattcaaga taaacgatat tactatggca atgatcccga tgccaaacaa tataactggc
    42841 cactgcttca ttccatgaat atcgaaaaat acatatctgc acaaaataaa gcctatacac
    42901 agcgcgccca gggacagcac atgaatcata atttttttct tgtttaacat ataatcattc
    42961 cccgattctt ctttcgtaga gcaaatccgt cttctttcgt agagcaaatc cgtcatgccg
    43021 ttgtacgatt gtgtcctcaa taatttcagc ttaatttccc tgttattttc tccaaaaagc
    43081 cggatcccgg aacctaaaat cgtcggaata accgtaatat aatagcagtc aattatgtcg
    43141 tctctgacta actgctggat caggtctgcc ccgccgcaga tccagatccc ctttccctcc
    43201 tctgcccgta atttttttac cagacgggcg ggactgtcat tgacaaaacg gatgctttca
    43261 gaggatactt tcgtgttatg agttatcaca taagcagtaa aatcagaata aacccattca
    43321 tccggtgaaa gctcagtcac aatttgatga tacgtattcc agcccatgac taccgtatca
    43381 atctcttttg caaactctga ataagagtct atgttgtcgt cgtcattgcc ctggcctgcc
    43441 agccagtcca cgttcccttt actgtctgcg atatacccgt cgagactcat cgctataaat
    43501 acggtgactt ttttcattga ttctccttta cagcctggaa tctatcaatc agtaaatctc
    43561 aataagtatc catctggatc ttgtactaaa aattcctttt gtgtaatata ttcaccatta
    43621 acttcatatt tattaagtat catagaacga tataatggat attcatttaa tatgagttta
    43681 tggtatatca tatcaacatc ctctacctca atggaaaagt taataccacg cccaaaagga
    43741 tatgacattt ctgcaacatt ccaaccattt tcatgcatct cttcaaacat caattgagtt
    43801 tcctcaaaag atagaaaaat aaatctatct gcctctcttt catattctaa tttttgtttt
    43861 gcttaacttc cgattttctt gttcttttcc gctccatctt cttgccctta cggacaagaa
    43921 gcatcccctc gctttgctcg gtcaattcta atttaccatc cacctggcag acagaataag
    43981 ttatcgcagt attcttcatt ctttttcact ttaacttctt ttcctatact caaaatagcg
    44041 tcagtgtgca aaggacaata cggtcagaaa tgcgcagatt gcgtgtctgc ttcgttactt
    44101 tcgctccgtg tacgtccagt acacgtcgtt ccagtgcctt gcagaacgca caatctgcgc
    44161 tatttttgac tcttcgacct caagcggaga gaattgcgct gttttcaagg cagaggattg
    44221 aggtgtacta aacgtacacc gattaacgat aacgcagaaa acggcgcaat tatcccgcta
    44281 tgaggcgtgt tgtcccttgt acactgatgc taccatatct gttttttcat ggcaagctgt
    44341 tttcagctgt gcaaatccat cccactccag cctcctcccc acaaaaaaaa gaagaacaga
    44401 aagcttcctg tgactttccc ttcttctttc ttctcttctt ccttttacag cttcatcagg
    44461 tactccccga tttccctggc caggcggagg gccgtgggga gcagctcgtc cggaaaataa
    44521 tttccgtagt tgttggcctc gaagctgaaa tatccggtgt agccgatctc tcttaatgtc
    44581 tgcaccactt cgttccagtt tactgtgccg aacagcggca tcacgtgcat cagatccgga
    44641 tctgtcatgc tgtgggtgtc tgagacgtgg gtgcccttta aatgctttcc tatatagagc
    44701 agggactgtc tctgatcctg cttcataata tccgcgtgct cgaaatccca gcagattccc
    44761 attctctcgt cgtcaaagga ggtgacgaaa tccaccatct cctccggcgt agcgcagtat
    44821 ttgcgcttcg gggcaatgga atagtcgcac atattttcaa tggcaaaggc catggggtat
    44881 ttctccgttt ttcttaacag ctcctgaaaa tacgccgtat tcttctcctt ggaggatttc
    44941 accagagccg ggctgtcaaa gtctgtctcc gggtgggtta cgcagagggg agagcccaga
    45001 gccgcgcagc agtagatgga acgctcgacc agctcctcat ggcgggctct ctcagcggcc
    45061 gtcatcggcg cgcagaaatt gtaggtgtag gcgtggcact ggccgaagga aacgcccagc
    45121 tcgtcctttt tcctctcaat gcgggccagc cacttctccc actgatccgt caggaacggg
    45181 gaatggggca gggaccagtc gtaaaagctg atgtcgaagg tgtcaaagcc cgccgcaaag
    45241 gccagttcca tcatatcctc catgggcata atactcttgt ccggcctctc aaatacgata
    45301 ttggtggatg tggataattt catattttaa aacctttcca tgtttcattt ttcatcttaa
    45361 aaaggcagag gcgtaagact gcctgtaaca aaaatgttct aaataaaatt gaatttttcg
    45421 ttttttaaaa aaatactttt ttaagaaaat actcgttttt caagaaaact taaaagcttc
    45481 tcccagtcgt agtcccaggc cgcctgaacg aaagatccct gcttcttaaa tctgccgctg
    45541 tttccaaaga gcgtctgccc tgtggtgtac tctcctctgg tctccactat cacatgtccg
    45601 gaaactgttt ttgctatctc cgggcagaga gccagacaga cggccgcgct gtctaccaaa
    45661 aggctgtagg gatctaaacc gtgatccagg ttgaactgca ccgcccgcct taaaaacttc
    45721 gttttttcgt tttctcccgc tctggctaac agccgatcca tcatggaatt gtccaggcgt
    45781 ctcgtcacgt ccagccccgc cgctgtgata ggaatgccgg agccaaacac cgccgccgcc
    45841 gcctctggat cctgggccag gttccactca ggccgtggat ttagattttc ataatccggc
    45901 cgcaggccgt agcttcctgc tatggtgtaa atcccggcgg cggctaaagc cgccgccggg
    45961 tcgttctgaa tcatcaaagc cagatttgtc ataggcgcca aagagataat ggacacctgg
    46021 cctggaaagc gttttaccgt ctccgccata aagcgccagg cctcccctgg ctcctccttc
    46081 ttcgccggat ccggaagtcc cgtctgggac aggccgtcgc agccgcagta ggcgtcgtca
    46141 aactccatgc ggcgaacaag gggcatttct gccccctgta ctgccggaat ctcctctctg
    46201 ccgcaaagcg tctggatctt caaaatattc ttaatgcttc tggctgaatc gcagactccg
    46261 aaggcagccg tcattcccag gatctccagc tccggcgaaa ccatggctaa catcaaggca
    46321 accgcgtcat ccgcgctggg atcagtgtca ataatcacct ttctggttat tctgtctgtc
    46381 atactgtttt attctccgtt tgcgcggtag tagtcgttga aaatctggtt gcagccgtcg
    46441 ataatcgctg tctttgtatc ctctgcagag gcctgtccgt ttccgaacat cagcatggcg
    46501 tccttgatcg ttgtgtccac tgcgtcagag tttggcacaa acggagccag aactgcctcg
    46561 ttggccttca tcatcacctc acccggaact gccagctgcg gagtctctgc aatggcgttc
    46621 tgatagctct caagctccgc gctgttttta ttaaccggaa cgtatcccgc tccctctaac
    46681 cacatagcct gagcctctgg agataccatg tactgctcga actcccatgc cgccttcact
    46741 gtctcgtcgt cgccgcggtt taacaggaag agtccggaac cgctcgggta agcgcctccg
    46801 atatcgtcgg aagttaccag cggaatctga gctacgcccc agttaaagct gtctccaact
    46861 aactccttaa tggtaggaat acgggagctg ctcccgttcc cttgctgcag ccttccggca
    46921 tggcctcaaa acagcggctg ccgtaccgga ctacgtgaat tctgtttttt tcctcctcga
    46981 gaagagggcg aagcatatcg cactggccgg ggctgtccgg atcaataatc ataagctttt
    47041 gaagcctctg cccgttccat tcgtcccctt ccggatggat cagatgtttg taaagaccgc
    47101 tttcctgaga tttccggcgg atatagtcgt tctgccggta aactccctct gtgttctcat
    47161 ctgtcaggaa gacagcaagc cccatacggt ccgcctcctc cactgtgcgt ctcaccgcat
    47221 ctgccggaag aagctcttcc cagataaatt tctctccgtc gtggcccgcc gctccgttgg
    47281 acgctacgac cggaagtgta atgttaagag cctttttgta ctcctcaagc attccgaccg
    47341 gtcttccgct ggccagtgta aaggcgatgt gctgttcaga aagcagctgt gcaagctgtc
    47401 tgattccttc gcccatgacg cagtccgcgc caaccagggt cccgtccacg tcgctgacta
    47461 ccaggcgcac ctttgaactg atatctgcca tatctgcctc ccatctgctg atccaaacct
    47521 ctgcaaagct ttttcttctt aattatattg aattttcgcc tctgcgtctt tctctcttcc
    47581 gactttttta tcacttttcc gaccttttta tctctccgtt tttacaaatg caataaaaaa
    47641 atgctattta cattttcatt tctcgacata aatagcactt tttcgatata attgtatttt
    47701 tcagacttac acttcgcgaa accgcttttt atactgcttt ggagtatatc ccgtctcctt
    47761 gcggaacatc ctgataaaat gggaaaaatt gtcgtagccc acctcggcgg cgattccgct
    47821 gaccggcaga tcagaatgct tcagaaggtg ctctgcctgc ttcatcctct ttttaatcgc
    47881 gtactccttc accgtcatgc ccgtttcttt cttgaaaatc cggtttacat aatcaggatt
    47941 cagattcagt tccctggcaa tttccttccg gctgattcca gtcttcaagt tttccttgat
    48001 cattcctttg atccggcctg ccagctccgc cccgctgctg tttccgtccg ggaaggacag
    48061 gcgggtgatc agctccatgc acatgcggat ccagcggcac atatcgtcaa tggaaaaaca
    48121 ggcggttttg taatgctggt aaacctcctc gtcctcaaac agctggtggg ccttgatctc
    48181 cctgtactcc atgcaggcga aaaacatctg cagaatatcc tgctgcagaa tccgaaagct
    48241 catctcgtcc agccgctttt tcttagcctg ctctaccaga aaacggcgga ttttctccac
    48301 cagtccgtcg gtctgcccgg caaaaatcag ttcaccccag tcggagggaa ggataatccg
    48361 ctccttcaga cggcggtctc cctcctcccg ctctccgtcc ctttgcgtca catactggat
    48421 gctgtcctgg cagagcacgt cgtccttgct gaaacgcagc agccgcgaat aagttttttc
    48481 catctcctcg cagaaaatat ctccgctgac gtagcacagg atctgggcgc cgaacatgtc
    48541 ccggcaccgc tccaccaatc ccggaccgat ttcccggaaa cgctcccctt ctttctcatc
    48601 taaaatcacc accactctgg tgtagatgac aatgacctgg ctggtctgga cgtttccctt
    48661 caccactccc ttggccaggt tctgaatggc agactggcac agttcctcgc cccagcgtct
    48721 ctgaacctct tccacatttt taatagtaat cagcaccatg cggtagcggg cgtcggcgtc
    48781 caggcggatg ttgcagccgc gggccttcct gctgataatc tccggatcat ttctgattct
    48841 tcccaggcac acgtccttcc agaacagctc cttgatagcc atatgatttt ccatccagca
    48901 gtcgccgtac tcctttttca attcttcctc ctcacgcttc cgctgtctgg ccagaatccc
    48961 ctttaccgcg cttctcagct gattttcctc caccggcttc agcagaaaat caccggcctc
    49021 caggcgcaga gcttccctcg taagctcagg actgcaggaa gcgctgatta caatgacgcc
    49081 tccccggtag ttctggccgc gaagctctct taaaatttca atcccctcat ttccaggcat
    49141 gtcggcgtcg cagacaatca gtcccgccgg ttcctttttg agctgggaaa cagcctgttc
    49201 ccggctgtag gccgacgtaa tcggaaggat atcctctgtc gttttgctga gagcaatttt
    49261 cagagcgcgt atggtatttc tgtcgtggct gataagcatg agatgcataa gcgtattctc
    49321 cgtttcctgt ggtatatgtt ctgggcgcgc cagtatgcga agggtttctt acccctgctg
    49381 tcctgccgtt gctggtgaat ccagtatacc agcatcagcg gagcgtttca atgagttctg
    49441 tggataagaa aaattaatca ggcccgggca gtcggctgcg ttttcggctc gattcgcgca
    49501 tctatgatcc gccgttcgcg aaaactcgcc ttacggctca aacacttcgc tcggcggcgg
    49561 aaatcagcgc aaatctcgct gcgaaagcct cgccatcact gcctggcctg actatttttc
    49621 tattgaaaag tataatcaat ttgcctcatg cagttttttt cttcccctcg cgttttaccc
    49681 tctaccagat caaaaccgcc agaaacagca gattccacca ggtaaaaacc gccagatagc
    49741 gccccttctt ctccggatat tcggccgcca cctgcttgta ggaaatcagg ctggccatgg
    49801 acgcgatgag ggttcccagg ccgcccagat ttgttcctat aatcagctgc tcccactgat
    49861 ctgtgaaatt ggacagcaga agagccgcag gcacgttgct gatcacctga ctgattccga
    49921 tggcagccac tttctcatgg cctgcaatca tattgaccac aaattccctg aacggcggga
    49981 aacgattcat atttccgata aacacaaaga agaacagaaa cgtcaggagc agggaatagt
    50041 ctacttttct aaagaggatt ctgtctctat acatgacggc cgctacgaca gccaggagaa
    50101 ggccgggagc tggcagaacg ccgcccactg tctgaaggca gataaaaaac aaaaggaggt
    50161 aatagaccgt cccggaagtc tccggctttt tcgtctgctc tgtcatggtg acgcaggttt
    50221 tctcctttcc caccccaaag aagacgcaca ggcacagcag aagcgccgcg gctgccgtat
    50281 ggggcagcat cagccttaaa aacgctgaaa gagtcattct ggaaatactg taaaggtata
    50341 aattctgcgg atttcccata ggcgtaaaca tacttcccag attggcggca atggtcataa
    50401 gcgtgacgac gcggcacagc cgcccggtca ttccggccat cttcagaatc ataatgccaa
    50461 aggggacaaa ggtaataaga gccacgtcgt tggtgataaa catgcttcca aaaaagcaca
    50521 gaaaaaccag cagaaatacg atgccccgct ctgattgaat cctctccaga agccgttctc
    50581 ccacataccg gaacactccc aggccgctga gcccagccac cactgccatc aggcagaaca
    50641 ggacgataat ggttcccata ttggaagaaa aataattcag atactcccga tccggcctta
    50701 ccagaaagca ggaaagaagc gccagcaggc cggagacagc cagaacggtc tcctttttca
    50761 aaaattctat gacagcttta aacgataggc tcatgatacc tctttctcct tctccaaaaa
    50821 ttttctgtac gtcagatcca ttcccactgc tcccagaggc gctgtaatga gaatggaaag
    50881 cacagccaca gacagcacca gctggccgca gggcagcccc gctgccagag gaacggatcc
    50941 aatagccgcc tgaactgtgg ccttaggaag ataggcgatg attccaaaca aacgctctct
    51001 tctgttcagc tttgtgcctg ccaggcagag gcagactccc accgcccgga atcccagggc
    51061 aatggcaatc atcagcacag cagccgcccc cgctcccatc gtatagcgga tatccacaac
    51121 tgcgcctacc agcacaaaca gcataacctc agccgcaacc caaagctttc cgaatttttc
    51181 agccagacgc tttgacacaa tcggagcgct ttttattttt atcatacacg ccatactgac
    51241 cacggccaga aggccggaga cagaaacaac gtcctccagc caggcttcca ccgacatgag
    51301 aaggaaagac gttcctaaaa caatgaccac cttcatgctg tttctgatat aacgcttttt
    51361 ctcataggct ctctcaaaaa aacggctcag cccatagcca aaaacggctc ccagaaggat
    51421 tcccagcaca atggaaacgg gaatattcag aaaatcagcc gccctgacgc tttccccctg
    51481 ggccatgccc agaaaggtgg aaaaaagcac gatcacaaaa atatcgtcgc aggaagcccc
    51541 cgccataatc atctggggga tactcttatc tgtaccgtat ttttcctcca tcagctgaac
    51601 catccgcgga atgaccactg ccggtgaaac agccgccagc acagagccca gaagagccgc
    51661 ctccacccgt gaaattccca gaataaacgg gccgaaaagg aggaaggcca aaatctcgaa
    51721 gctggccggc acaaaagaca tcatcaccgc cgggcggcct acctgccgca gatccgacag
    51781 attcagggaa agccccgcct tcagaaggat aataataagc gccatctggc gaagctgcgg
    51841 ggaaatcagc agaatcgacg aatccagcag attgaaaaca ttcggcccca gaagaatgcc
    51901 tgtaaacagc attccgatga ttcggggcag ccccagtctc ccgcagatgc cggccatggc
    51961 cagaccagcc agaaaaataa atgccaggga tgtaagcatg atcgtttctc cttagttttt
    52021 gtaaaaatga agctcttttc atggcagagt aagttccaga ccacacaaaa aagctgacaa
    52081 tttctgcgat ggttgtcaca gaagtcatca gctctatcag cggttttggc ttgccatggg
    52141 agaacttcat tccctagttt tattataatg gaagggggag gctttgtaaa gcggaaatac
    52201 agccggcttt cttaccccct gtagtaagtg tcgatggttc catcctttcc cttgctcttc
    52261 tctcaatatg taattttcag tatcttccta tttcaccata tctctcatcg gcggtactac
    52321 gaactccggt tttctgccgg acaggaagtc gtcgattccc cgggcgcaga ttaaggaaga
    52381 acgggaagaa gcctccttgg tagctcctcc gatatgcggc gctgtcacta cgttgtccat
    52441 gtctaaaagc ggattgtcct tctccatcgg ctctttcttc agcacgtcga gggctgctcc
    52501 tgcgatctgt ttctccttca gagcctcaat cagagcttcc tcgtctacta ctgttccgcg
    52561 ggacgtgttg attaagaatg ccgtcggctt catcagctgg aattcctttg ctcctacgct
    52621 gttcaccgtc tccggagtag ccggaacgtg gagagatacg taatctgcct tctcaaatac
    52681 ttcctctctg cttccagcca gctcaatgta atccagaaga tcctttgcat acggatcgaa
    52741 agccagaacc ttcatgtcaa agccaagagc cgccttcttt gcaaccaggc cgccgatatt
    52801 tcctacgccg atcagaccca gagtctttcc gtttaactcg tgcttctcta cattgaattt
    52861 tgcgaagcgg taatcgtctc tgtagagctt ctgaaccagc ttgaaatttc tggagcagtg
    52921 gagcatatag aaaatggcaa gccctgctac tgactggctg tttgcccttg gagcgtagag
    52981 aactacgatt cccttctctc tggcagcttc cagatccacg ccgtcaaatc ctgctccgtg
    53041 gcgggcgatt acctttaagc tgtctgccgc ctccagaatc cttctcgtaa tcttggctgt
    53101 gcggacaatc ataccatcgc agcccttgat atccctgata atatcctctt cctcaaatcc
    53161 agaaccgtct accagctcat agcccttgtc cagaaggtac tgtcttcctg actctaaaat
    53221 tggctgtgga agtaaaatct taaaactcat attcctaatc ctcctgcttc tttctatttc
    53281 attttttatt ttctgctcat ttatataagc aactttcgtg ccaacttttc caaacaatgc
    53341 tttttttgat gatttttttc atttttatcc gtttttcagg ctttttcccc tccgatctgc
    53401 gcataatata aaagaagccc ggggaagaaa ctccctggac ttctttcatt ctctgctttt
    53461 ttgttttatt tgaatggttt atttcacttt catttcattc ttttgctgtt tttatttcat
    53521 ttttgaaata ttccatcccc ctccatttcc agtatctctt tacaaaccca ctcttttttc
    53581 tatactttga ttaacaatat ccttcataaa tgacagaaat cattcatctt ttttctatca
    53641 tttatgaaat tcaaatctat ttcaaggggg aaatgaccta tgaaattatc cagcgccgct
    53701 cctgggggcc aggcggcaga tatcgttatt ttcgcagcct ctgagacctt cgcccagact
    53761 gccagggaac tgattctgga acgccgtctg gagaatcaca ttgcagtcac agaagccact
    53821 ggggagagaa ccttaaagct tgctctccag tttgcgaggg agggaagccg cgtcttcatc
    53881 agcagagggc ggaacacaaa gctgatcgag cggcacgtct ccgttccggt catcaacgtg
    53941 ccgtacctct gcgaggaaat ttacagttcc tttctggcgg ccggggcgcc tcctgagagg
    54001 gtggccatgg tgggcttcga ccgggcctac aatattatga aaaccttccg ccgcatctcc
    54061 ggcctggacg tgcagctcat cgaacctcag tcccccggca ctgtcatcaa agagctgaga
    54121 gaaaagcttc ggcctggaac agaggcgtta atcggaggct tttctgtcaa gcgggctatc
    54181 tccgagattc aggatctggg cctgcgccac attcctctga ctgtggagcc gtccaatatc
    54241 tccctggcca ttgacagcgc gttaaatatc ctggcctcta tggatcggaa ggacgaattc
    54301 cttaccacca tttccactac catcaacagg atttccaatg ctgtgatgaa tttcgacgta
    54361 aacggaaagc tcctcttttc caacgccagg gcggatcaca tgccccagtc tgtcaaaaaa
    54421 tatctgttta ccggagaagc ggccttttat ctggagctgg acggcagaac gcctgccgat
    54481 tcccgcaccg cgccgaaaaa ggagcagatt ctccatgtgg gatacgatac ctatgtggcc
    54541 gaatatcttc ctgtcatcgt caatagaaga ctgaaaagca ttgtagtgat tgtttccagc
    54601 gaaaacagca ttcagatggc cgaaaaacgg ctgcgcctga gccagagcaa gaggggctac
    54661 acggccaaaa accacttcca cgatatgatc ggaaacagtc ctgtttttca ggaaaccata
    54721 cagctggcga aaaaatacgc ccgttcccag agctctgtgc tgatcacagg ggaaaccgga
    54781 acgggaaagg agctgtttgc ccagagcatc cacaatgcca gctcccgctg cagcgagcca
    54841 tttgtagcca tcaactgcgc ggcccttcct cagtctctcc tggagagcga actgttcgga
    54901 tatgtgaagg gcgctttcac cggagccagc aaagagggga aaatgggtat cttcgagatg
    54961 gctcacagag gaaccgtatt tctggacgag attggggaaa tggatttaaa cgtgcaggcc
    55021 aagcttctgc gcgtgcttca ggagcgggag gtctgccgcc tgggagacga taaaatcatt
    55081 ccggtggata ttaggattat cagcgccacc aacaaggatc tggaagagct ggtgcgccag
    55141 aagctgttcc gggaggatct gctctaccgc ctgaacgtgc tggagctgcg cctgcctcct
    55201 ctgcgggaga gaaccggcga tattcccctg ctgatcaagg catacaacgg aaagcagaac
    55261 catcctgtca ccttccttcc agaggcagtc cggcttttag aggcccagcc ctatcccgga
    55321 aatatacgtc agctcttcaa tttgctggag cggacgatta cgctgtccga cggagatatg
    55381 atagaggcgt cccagctggc aaacattctc caccttccct tctccagcgc tttgccggac
    55441 tgcggttcaa aagaaccggc cttcccggat cccgcttcag aggcctcctc ttccggctgc
    55501 agcgtttcct ccctcgattc ggccatggtt ctctgcgaaa aagaacgcat tctggaaacg
    55561 cttcgcaaaa acagaggacg cagaaaggag acggcagagc agcttaacat cagcccggct
    55621 actctctgga gaaaaatgaa aaagtacgac attttttagc cggctttcaa aaaatcaagg
    55681 gcagaattcc attttccgga ttctgccctt gatttttgtg catattgtat acatttctac
    55741 agttttcttc atgtttttac aaatttagtc acgttttttc tcactctctc ccttttcact
    55801 tttacctttt tatagtatta tattttttat cggcctttta acacggcatt tttcacaaat
    55861 tttgggaggt attacgtatg acaactattt ttctaggcat gggactgctg ctgctcacgc
    55921 tggccggctt ttctctgttc agcatgaaag ctccgaaagg ctctgcagcc atgtccggtc
    55981 tggcaaatgc agctgtggct acctttctgg tagaggcagt tcacagatac atttccggcg
    56041 atctgttagg ctctgcgttt ctcggcgagg taggctctgt atccggaagc ctgggcggag
    56101 tcgcttccgc tatcctgatt cctatcagca tgggggccaa tcccctgttc gcggttgtag
    56161 cgggcgttgc agtgggaggc tacagtatcc ttccgggctt tgtagtcgga tatctgatcg
    56221 gctttattgc tcctgtgatt gaaaagcacc ttccagccgg cctcgacacc attctgggcg
    56281 ctctgcttct ggctcccatc gccagaggca ttgcctttct caccgatccg gttgtcaacg
    56341 cggctatggg atatatcgga aatacgatca ccgctgccac cgaccagtcc cctgtcctga
    56401 tgggatttct cttaggcgga attattaaga tgatctgtac gtcgccgcta agctccatgg
    56461 cgctcaccgc catgctggga ctgaccgggc ttcccatggg aatcgcagct atcgcctgct
    56521 tcggaggttc ctttaccaac ggaatcatct tcgcccagtt aaagctggga aaaccaagca
    56581 atatcgcggc cgttatgctg gagcccttaa cccaggccca catcattacg cgccacccca
    56641 ttcccatcta cggatcgaac ttcttcggcg gaggtctggc cggcatcgca gcggctttgc
    56701 tcggcatcgt aaacaacgcg cctggaaccg cgtcccctat tccaggactg ttagctccgt
    56761 ttgcctttaa tccgccggtc aaggtgctca tagctctggc tctcggcgca gtcggcggaa
    56821 ccctggcagg ttttgccgga agcattgtgt ttaagaagtt tacacaggac gaggcgtaaa
    56881 agaggtaaat gaagattgga aaaaaagcag atttccctgt tctgaggaat gggagagctg
    56941 cttttttaat acaaacagag gaacacaagg gcggagacag actgcatttt ccgtctccac
    57001 tcctgtgttc ctcctatcag ctatatactg ctgcaaaaag atatcctctt cctcctctgc
    57061 ggctactcgt tctgtacctc accaaaaatc tcatctctgg ccccttttat ggtcaggtca
    57121 tattttttgt gatttacaat cagtattcca agggaggccg cggctcctat cataatcaaa
    57181 gcggcaaaca taccgccaaa attagcgatg atttttactc cgtctactcc tatgctggct
    57241 atcataatgt agcctactgc cattggaatc acgccccaaa ctaatttcag ccagttggga
    57301 gcgtctggat tatcaggact gatgcctcga gtagaaatac ctgccatggc tatcatattg
    57361 gaattgcagg ccgtaaccgt cgataaaaag atcaatataa taaacagcgg aataattacc
    57421 gcgctgagcg gcatcgcgcc aagcatatcg tagggcacat tttcaactcc cttcgcatag
    57481 gaagcgcata agtctaccgt tcctgaagtc tccatccaga gagacgttcc gcttaccagc
    57541 atcatccaga ctgcgctgat tgtagcgcat actcccacat acattccaag aatatgtttt
    57601 accttgcgtc cataagcaat acgtcccata aacgctccgg atgtaggcgc ccatgccatc
    57661 cagctgaacc agtaaaaggt ggtccaccac tgcggccact ggcttccagc tgactgacct
    57721 gtaattaaaa ttctttccaa gaaggttcct gcaaagccgc ccaacgcttc tgtagaaaga
    57781 ttaaacaaaa acgatgcatt tgaaaatatt aacaggaaaa tcaaaaaaat tgcaaatcca
    57841 tatacattaa tattggaaac cttcgtcatc gccttctgaa taccggaaat tgccgtagca
    57901 atggatactg ccccgactac aattccaacc atcagccaaa gcttgggatc agaaggcagg
    57961 cctgtcagct tggaaatgcc tcccgaaaca ttcataaaag cctgggcgac tgagcctgcc
    58021 attccagctc caatagagaa cagagtgact gcgtccacaa tctgcattac cataggacgg
    58081 tatgcccttt ttcccagaag aggagccatc tcgctggtaa tggagaaagg cttctttcca
    58141 ttgtaataca tgaatgcaaa tactaccgca ggcaccgtat acatggcgta aggcactatc
    58201 gtccaatgca aaaacatagt ctccatagaa aatttcagcg cctccggagt cttaggctcc
    58261 accccgtaaa tctcagtggg aggcgacata tagtgggcaa tgggctctcc aggcccccag
    58321 aaaagaacac cggccgccat ggtagtagtt aacgcaatgg taaaccatgc gaaattggac
    58381 agctccggct ttgcgtcctc tcctccgatc ctgacgtctc caaatttaga gaatgccgct
    58441 atcactgcca ccactgtaat tacaagagcc agtatgctgg ctgcccagcc aaaatgagcg
    58501 ataatggcat tattaattgc attgacaatc cccagaaaac cgtccttatt tacgatactg
    58561 agaattacaa atatactcag cagaataaac ggtggaaaaa atgtcattgg ccgcatggaa
    58621 agctttgtct tttgtttctc tcccatttac tgttccctcc attccttcaa aagctctctg
    58681 taatcctccg gatgacgatc tgacagaacg gtattaaatt ccctttcctg ttttacctgt
    58741 gcaaggttga tttcctggaa aagaactccc tcctcttcta cgccaaaggc gctcagcact
    58801 tttcctgtcg gatcaatcac ctggcttttt ccggcaaata tctcatcatc tgacggacca
    58861 cagcggttta ccgccgctac atacaccaga ttatccagag cacggcacga taaattcaaa
    58921 tcccaccact ctttaaaata atagctggct ctccaggctg ccgggactaa aataagctgc
    58981 gctcctttca aagctaaaat tctggcagtc tccgggaaac agacgtcata gcagatcaca
    59041 attcctattt tccccagctt tgtttcccag acaggatatt ctgttcctct ttgaaaataa
    59101 agtctctcgt ctcctaccgg atgcgttttc gaataggttc ctactacgtt tccctcatca
    59161 tcaatcatca ccgctgtatt ttctgtttcc ccgttctctg ttaaatacaa aacaggagcc
    59221 acaatatgaa tatgaagctc tgctgccaga ctcctcatat gactgacaga cggcccatcc
    59281 agaggttccg ccattgcttt catatctaaa attctgctgc ccagatatcc gccgttaaac
    59341 gactctggaa ggcagactaa agccgcccct ttctttgccg cctctctgat atattgttca
    59401 gccttttttc tattttgttc ctgctctccg aatgcgcagt tcatctgcac taaagcaagt
    59461 ttatattgtt ccacctgtaa tcccctcctt acctccagtt cgactgtttt attatcttgc
    59521 gtttaaaatc tccgcctccc cctatatctc cctaatcata tcaaaacagc cccctgctgt
    59581 cagtttctat cttttatcgt gacagcaacg gggctttttt atcctatctt ttcagttatt
    59641 tacagattta gatatgcgct gcaaaaaact cattcattgc gtcacaaagt ccaaccagct
    59701 ttggatcgtt gtcaaacatc cattcattgt gttttccctc aacaaagtac agagctttgg
    59761 gctcattagc caatctgtat gcgtcgtctg cctcctctct gtcgtgaagc tcattgtatt
    59821 ttccatgtcc tacaaacacg gcgcagtcag gagccagctt cggcagaata tcctggacgt
    59881 tgaaacggac aaaggactct gcaattacgc tggacatcgg tgttggaaac ggctctttgt
    59941 aatctccttc gatagaatct tccagtcctc catttaaatt tttcagcgtc ttttctacat
    60001 agaaatcacc agattcatca atatttggat agaattcgta cgggtggcgc agaaccggat
    60061 ctcctgtgct gactctcttc catttatcct cctcaagggt gcgcagcatc ttattatact
    60121 tatcatttcc cattcccatt ctcatccatc tgcgtccgtc tgtaaaggaa ttcagcgttg
    60181 ctaccgcttt tacagtttta tctctgtaag ctgctgtcac acataccgcg cctccaacac
    60241 cccagccgat taatgcaata tgctccggat ctacttctgg ctgatgttta aagaaggtaa
    60301 ctgcattatt cacatcgtct acctccatct ccagagtcgt atatttttcc attaaaccga
    60361 ttccgcctga cggtttaaag ccgcggtaat caaatcccat gcagacatag ccatattttg
    60421 tcatctggcg ggcaaacata gccggatata ccttgttaag gcctgtccat ccggaattgg
    60481 cgatgattcc cggacgtttt tccccttcct tataatcatc tggcaggtaa atagttccaa
    60541 ccatctttgt gccttcgctg taaaatacaa cttctctcat cttcatatcc ttctcctctt
    60601 ttctttgata ttatccgttc aaggtctccc ttgtcttggc ctcattatag tttacaaaaa
    60661 agaatatttc aacctttttt cattaaaaac att
//
LOCUS       DBMDUW010000011        56319 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_564_length_56319_cov_4.000036, whole genome shotgun sequence.
ACCESSION   DBMDUW010000011 DBMDUW010000000
VERSION     DBMDUW010000011.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 56319)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 56319)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56319
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_564_length_56319_cov_4.000036"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(148..981)
                     /locus_tag="ACZPCR_03850"
     CDS             complement(148..981)
                     /locus_tag="ACZPCR_03850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008707806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvfB family protein"
                     /protein_id="HIR1230041.1"
                     /translation="MIELGRKQELQVLREKEFGVYLGEKAHPEASVLLPKKQVPEGTK
                     LGDSLQVFIYKDSEDRLIATTAEPKLEAGQTALLKIKEITKIGAFLDMGLEKDLLLPF
                     KEQTARLRPGDDCLAALYVDKSSRLAATMKVYPYLQTAEGYQKDDKVEGRVYEINDRL
                     GVFVAVDDKYYGMIPAKEAFRPFHIGEVIEARITKIRPDGKLDLSCREKAYLQMDKDA
                     EEILKVIDEFDGALPFNDKASPEVIKREFNLSKNAFKRAVGHLLKEGKIEITETSILR
                     K"
     gene            complement(983..1735)
                     /locus_tag="ACZPCR_03855"
     CDS             complement(983..1735)
                     /locus_tag="ACZPCR_03855"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006782128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016297 - fatty acyl-[ACP] hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HIR1230042.1"
                     /translation="MYTFESRVRYSETDETGRLSVTGIMNYFQDCSTFQSEDLHMGIS
                     YLEEEKRAWWLNSWQIVIDRYPSLGEKIQISTYPHGFKGIYGYRNFLIRDESGAVIVK
                     ADSCWFFYDLEKGCPARVTPKEIRGYGECEAPLPMPEAPKKIRLSEHYWEERPVEAAR
                     HHLDTNLHVNNAQYAEIAREFLPGDFEIQELRVEYKKAAVLGDKMVPRISREEDGYTV
                     SLTGEDGSPFANMYLKGSCSGSRDGQEKRKDG"
     gene            1910..1981
                     /locus_tag="ACZPCR_03860"
     tRNA            1910..1981
                     /locus_tag="ACZPCR_03860"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1942..1944,aa:Gln,seq:ctg)
     gene            complement(2156..3181)
                     /gene="queA"
                     /locus_tag="ACZPCR_03865"
     CDS             complement(2156..3181)
                     /gene="queA"
                     /locus_tag="ACZPCR_03865"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006863453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HIR1230043.1"
                     /translation="MNVKDFYFDLPQELIAQDPLEDRASSRLLVLDRETGEVTHRKFR
                     DILGYLNPGDCLVINDTKVIPARLIGSREGTNAKIEVLLLKRRENDIWETLVKPGKKA
                     KPGTVICFGDGLLKGTVIDVVEEGNRLIQFSYDGIFEEILDRLGQMPLPPYITHQLQD
                     KNRYQTVYAKHEGSAAAPTAGLHFTKELLQEIEDKGVKLAHVTLHVGLGTFRPVKVEN
                     VLDHHMHSEFYMVEESEAEKINQTKRDGGRVICVGTTSCRTIESASDENGILKAGSGW
                     TDIFIYPGYQFKILDCLITNFHLPESTLVMLVSALAGREHVLAAYEEAVKERYRFFSF
                     GDAMFIK"
     gene            complement(3218..3979)
                     /locus_tag="ACZPCR_03870"
     CDS             complement(3218..3979)
                     /locus_tag="ACZPCR_03870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230044.1"
                     /translation="MGRSRKKPSGQPMSDRELRRFGILLAVPLLILALAAVLLTAGFL
                     REAGNKGQPEPESQLDSEAEQDVVIEPDTKEYHYDFGGSILEKDAHHEINQLMEEYFR
                     AVSECDMDTFMNLFTSQDTSQEEQFRQSFEKQREYIDGYENISCYTAKGLTEDAYVAY
                     VSYDVRFSGVDTPAPSLVEVYVEKCSDGQWRIFDGEKTPELEAYLEAVNRNEDTVLLG
                     KQIDEAKEAAMNADEELKGRILFMENGPGYMQDEE"
     gene            4097..4168
                     /locus_tag="ACZPCR_03875"
     tRNA            4097..4168
                     /locus_tag="ACZPCR_03875"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4130..4132,aa:Arg,seq:ccg)
     gene            complement(4217..4861)
                     /locus_tag="ACZPCR_03880"
     CDS             complement(4217..4861)
                     /locus_tag="ACZPCR_03880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004079519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HIR1230045.1"
                     /translation="MREAVFQVMDSWGSIGIFLLILIENLFPPIPSEVILTFGGFMTT
                     YTAMTAGEAIAAATAGSVAGAVVLYGAGRLATPSRLERFLGGRVGTLLHFQKEDVEDA
                     AEWFEKRGKAAVLFCRCVPIIRSLISIPAGMAQMALAPFLFLTTVGSLIWNTVLICAG
                     AAAGASWERVMETVDAYSNTAVWAAAAAILAALCIHRRGKKRAGNGKEAENGKK"
     gene            complement(4914..5942)
                     /locus_tag="ACZPCR_03885"
     CDS             complement(4914..5942)
                     /locus_tag="ACZPCR_03885"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230046.1"
                     /translation="MAGCSLLALCLSISSGLSGCGLSSGTGAVSGTLAQPGQELQETP
                     KEEKDLEFSRRFYLTSPDHLQLVTAEELEDWETSGTEKKELEEGKTSWGIVLAEFPRE
                     QVTMYGYLDPERPFQGVMIQCGDSVSYFPELVYMSDSHQMPDAVSDGSGSMFTVSFHA
                     ETGKDRKRDSLWVFLRSESGTMTADCFEEEDYLSQMANRFSLSFQKGEPEGTLLRQDG
                     QALGKADLSWAKDAEITGLNISDRVCFKPGNPARLETEIGISAEGRKPYYGDELAVTA
                     PIEIVVRTYEDGSRGAEFLIGEVEPLTEESLAEEREETGKIKDEAGEIKEEAEKGAGK
                     TEEQGHSE"
     gene            complement(6203..7438)
                     /gene="fliB"
                     /locus_tag="ACZPCR_03890"
     CDS             complement(6203..7438)
                     /gene="fliB"
                     /locus_tag="ACZPCR_03890"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015544828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin lysine-N-methylase"
                     /protein_id="HIR1230047.1"
                     /translation="MKHWKRDQETEKRKLRKTAAVPEYYKEFRCIGPACPETCCRGWD
                     IPVNQEAMRRYRSLKRAGFDFGGGIDFLRKKIRMKETGCPFLEDGLCRIHRDLGEKYL
                     CRTCRSYPRHAEDYGSRREWSLSLSCPEAAGILLRRRNGLKLHEYVLETGEEEPFLSS
                     LLKTRTLMFSLLSEGKVPLKYRLAMILTLAHDLQPSVKRAFRKETEDRGESLRRISRR
                     LARYELLKTPPGCQRFLKKLSEWENRPEERYDSMAGFLGVLGELPDIYPGFGSMISGW
                     MDLLYRTEAGYEDYRRRIVSAGFDRDVEEGSDLELWYENLAIHLLYVYVPGAVYDGEL
                     YSKVKFVLFFVLCIREAYGAAACEEKAERKKEELFITLVSRFCRQIEHSDQVLEQIER
                     AVREEKRFQMEYFLINLLN"
     gene            complement(7392..9875)
                     /locus_tag="ACZPCR_03895"
     CDS             complement(7392..9875)
                     /locus_tag="ACZPCR_03895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HIR1230048.1"
                     /translation="MDISEETGRAFRGMVEEAERLHLEYVTPELLLLHIAAEPAFQEA
                     FENCQGEIGRLAEQLEDYVNGLPVLSEEKRKEGAEPEASADLNELLLTAEWAARSSGR
                     KEVALSHLVSSYFSLKESFALYYLTEQGIEKGEFLLALIEAEEKDGGDEPSAACLYSA
                     EETGPGGKEEAEKLDEAEDAEDLEDEADAEGPENRRGKGRWKRFAVCLNEEISQANPL
                     IGREKELKRTMQILCRKEKNNPLHIGEPGVGKTAVVYGLARLLSEGKVPEPLKGAKIY
                     ALDLGGMLAGTQYRGDFEKRLKSVLSGLSQEEKPIVYLDEIHNIVGAGAVGEGSLDAS
                     NLLKPYLASGKIRFIGATTHEEYKRYFEKSRSLARRFQNVEIAEPGEDEAAEILLGLK
                     TRYEEYHGVSYQNGVIEYMVHMSAKYINERFLPDKAIDLMDEAGAYRKLHPLAQKRQT
                     VGKDVVDEILAKICRIPRQTVESSETRKLALLEKRLASQVFGQEEAVKEVANAIKFSR
                     AGLLDPGKPLASFLFVGPTGVGKTEIARTLAKELGISLLRFDMSEYEEKHAVAKLIGA
                     PAGYVGYEEGGLLTEAVRKTPHAVLLLDEIEKAHPDIYNILLQVMDYATLTDNQGRKA
                     DFRNVILIMTSNAGAGRMAKPGLGFSGSPEEETRNGDEAVLDEVKRVFQPEFRNRLNK
                     IVVFHSIGKKTARAVAGKKLLELGALLASRQVEFSYTRKALDLLAEKGVSREYGAREL
                     GRVIDREIKPLLVDRLLFGSLKKGGTCRLDTEQKDGTESVFAVREADGAKAQSRKGGS
                     CEPAEKRRSRKEGSFETLEKGSGDRKKKA"
     gene            complement(9964..10263)
                     /locus_tag="ACZPCR_03900"
     CDS             complement(9964..10263)
                     /locus_tag="ACZPCR_03900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013281468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0030163 - protein catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease adaptor ClpS"
                     /protein_id="HIR1230049.1"
                     /translation="MSAQTNAREHTKSRIKKPSLYHVVMHNDDFTTMEFVVEILITIF
                     NKGKEEAAALMMAVHKNQKAVVGTYSYDIARTKAEEAERQARAEGFPFRLTVEEA"
     gene            complement(10343..11479)
                     /locus_tag="ACZPCR_03905"
     CDS             complement(10343..11479)
                     /locus_tag="ACZPCR_03905"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008977440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HIR1230050.1"
                     /translation="MEKTAAEDAVKLLKDILEIPSVNGKDDEGAVAEYLDQYFKSYGI
                     ESRVDRIDETHANVIALIPGESGETEIWNGHLDTVPYGDLDKWETEPWKVEEREGKLF
                     ARGASDMKSGLAAMAFALAHLPGKPKHTIQFMGTCDEEKGGLGARRIVEESQMAASRF
                     MLIGEPTDLRPGAAQKGCLWLRLSVKGKTCHGAYPEKGANAIHGLFKTAEEIKAYVEQ
                     FSHPFLGQSTAQINWIGGGGAFNMTADGCEAVMDIRMVPGLDTAMVLERAKEAAGRLK
                     TENPLFDCTFTVENSRRAIEIEEEHEKVRRLKEILGERGLNQESIGINFFTDASILAE
                     HDLEQKILLFGPGKPNLAHQPNEYVETEAYLTAIEALMEMADCR"
     gene            complement(11693..12610)
                     /locus_tag="ACZPCR_03910"
     CDS             complement(11693..12610)
                     /locus_tag="ACZPCR_03910"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HIR1230051.1"
                     /translation="MKVLNFGSLNIDYVYSLDHFVQKGETISSRSLNIFSGGKGLNQS
                     VALGRAGAEVYHAGAIGQDGDFLTDILRDAGVRTEYVRRLSSVRTGNAIIQRDSKGDN
                     CIILYGGANQSIEKAQVDETLDQFSEGDFLVLQNEINELPYIMEQAHKKGLRIVLNPS
                     PMDEKITELPLSFVDIFILNEVEACQILKLPEAERREAAAKGNELCRRLSEAFPEAMI
                     VLTLGENGSVCLDHGVLTEQPIYRTETVDTTAAGDTFTGYFVAGLIRGLSVGEAMDLA
                     AKAASITVSGLGAAPSIPALAQVEGMKAR"
     gene            complement(12665..13414)
                     /locus_tag="ACZPCR_03915"
     CDS             complement(12665..13414)
                     /locus_tag="ACZPCR_03915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009534771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HIR1230052.1"
                     /translation="MAKKVLLAGESWMSYTTHVKGFDTFYTSVYETGEKYLKAAMEKG
                     GYEFTFLPNHLAMEEFPFTMEELKQYDLIILSDIGANTLLLPTATFTRSEIMPNRCNL
                     LRDYVLDGGALLMVGGYMTFSGVDGKGKWQDTAVQEVLPVQVLPTDDRMEHCEGVRPV
                     TVKEHPVLAGLDPEWPRVLGYNKTVLKPEAVEVAEVCGDPFIALGEYGKGRSAAFTTD
                     CAPHWAPPEFCEWKGYDVLFQNLAKWLMREE"
     gene            complement(13501..14784)
                     /locus_tag="ACZPCR_03920"
     CDS             complement(13501..14784)
                     /locus_tag="ACZPCR_03920"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HIR1230053.1"
                     /translation="MRDLKEVLAENRDKYIEQLKNLVSIDTHDLGHGIAGGLEKEGQD
                     YMLRLFEEMGAETAADPMKEEDIVRCKELYQEGNLGHNQTDRYNVYAAFKGNGAGRSL
                     MFNSHIDVMPADEIEEWTSHPFKPEIRDGKMYGRGTADMKGGLMASVMAVQLLKDAGL
                     ETLPGDVVITSVCDEEGGGNGSMQAIMSGQKADGVVVCEGTSDELILAHMGFVFFKVE
                     FEGKACHSGGKRNGVSAIEKAVKVMQALNEKEHEWLLTYKHPLLPAPNLNVGVISGGT
                     AGSTVAGECSFSACVHYLPIQMSYDQVVAEFEDVVRRVSLSDPWLEAHPPKVTIYQAG
                     GGFEMEEEHPFVDSFKKAYQAAKGKAVKVVGSPAGCDSRLWRNIAGCPTIQFGPGNLA
                     QCHGIDEWVSIDAYLESILIYAELILDFCSGGKNA"
     gene            complement(14804..15736)
                     /locus_tag="ACZPCR_03925"
     CDS             complement(14804..15736)
                     /locus_tag="ACZPCR_03925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009534773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HIR1230054.1"
                     /translation="MEREKIILDCDPGHDDAVAIMLAGKSPKIELLGVTVVAGNQTLE
                     KTQINALNVVQCLGLDVSVYAGCGQPMIRQKMTAGDIHGETGLDGPVFEPLTKELEKE
                     HAVSFIIRTLMESDGDITMVTTGPMTNLGMAIRMEPRIVPKIKRIVLMGGAYTNGNVT
                     PAAEFNIIADADAAYVCFTSGRPITMIGLDVTRKALCYPSIVDRMDKIGNKASKLFVD
                     LMRHFCKSQKEVFGWEGGPLHDPITIAWLIDPSVVETKPMHAEIDIRSVQSYGRTNCD
                     FFGYQKLEPNADVGIDIDAEKFWDMVEEVLKMYD"
     gene            complement(15785..16735)
                     /locus_tag="ACZPCR_03930"
     CDS             complement(15785..16735)
                     /locus_tag="ACZPCR_03930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007157123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1230055.1"
                     /translation="MELFENLGKIFNVSLIYATFRASTPIIYAALCAAITQQANILNI
                     GTEGIMLVGAFTAVAVSFFTGSWLAGVIAAMVGGAIIAMIMALGHIKYNSEICAIGMG
                     INLLAIAITKFLMQVLFKTNGTFSNPDIIPIPRVHFAFLENVPVLGELLNDWCFTEWF
                     VIIFIILLQFLFYKTVWGLRLRAVGQFPMAAQTAGIHVNAVKYQAMLISGLIGGLAGA
                     HLSLGYSTQFVENMTNNRGFMGVAAMYFGGANPVLTAIGCLLFGFSDSIGARLQAYGF
                     PAQFVLMMPYIVTVAVLAVSMALKMGAAKKRESSLMGKQA"
     gene            complement(16735..17847)
                     /locus_tag="ACZPCR_03935"
     CDS             complement(16735..17847)
                     /locus_tag="ACZPCR_03935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007157124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1230056.1"
                     /translation="MSQSLKGLRKILLTLALALGIGAIFILAIGENPLAAYGAVFKGA
                     FGTKLGFGTTIAGFTPLLLTSIAFAVAAKAGAFNVGVEGEVCLGGIAAAWIGVNCGFL
                     PKPILMLACFAGAMAVAAAWALIPAVLKAYYNVSEVCVTILMNTVALYIGSYLVSGPM
                     SAGTANPQSDPVLVTLPKIIKPSSANAGVFIAAGVVVLVIVMLYKTKWGYKIRTVGTN
                     PYHADYVGINSKKVFINAMLLSGMLGGIAGCIEVLGVHGYYLDNFAKDLGTNGMLAAL
                     IVKSNMIFTPFMAFFLAVLKAGAMAMQQSTGVPKSIVDTISAIFIIVATMELLFQFNG
                     KRKALAAQKKEMAAKTGGTGINDEAPKGNDREGGNK"
     gene            complement(17844..19412)
                     /locus_tag="ACZPCR_03940"
     CDS             complement(17844..19412)
                     /locus_tag="ACZPCR_03940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016441480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1230057.1"
                     /translation="MSEYVVEMRGISKSFGEVHAVREGEFTLKKGEIHSLIGENGAGK
                     STMMKLLYGMYPIDSGEFIIKGERITKLDPGTAIARGIGMVHQEFMLVNELTVLENVI
                     LGFEPKKGITIDFDKARKEVRHYIDQYNMEIQLDKKVSQISVGEAQRVEIIKTLMRGA
                     DIIILDEPTAVLTPQETKKLFEILFNLKKEGKSLVFISHKLNEVMEISDRISVMRQGT
                     YMGTVNKEETTPLDLTKKMIGREVFLNIDKSYGKAGEKILEVQDVWVPSQKESSKIRG
                     MSLHVNEGEIVGIAGIDGNGQSELIEAITGLRRVEKGKILLNGVDITNRSPRKVREAG
                     LAHIPEDRNKRGLNRDMSIEDNLIAVEIDKGVYTKGAFMNRAAQDQYAQEMTEQFDIR
                     PADYHLPTSSLSGGNAQKVVVAREVSMNKKLLVASQPTRGVDIGAIESIRNTLEQAKK
                     KGAGVLLVSAELEEIISLSDRIIVIHEGKITGEMEASEANENNLGLLMMGGEKAGQNA
                     AAQTDEIRKEGDEA"
     gene            complement(19591..20700)
                     /locus_tag="ACZPCR_03945"
     CDS             complement(19591..20700)
                     /locus_tag="ACZPCR_03945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family lipoprotein"
                     /protein_id="HIR1230058.1"
                     /translation="MKKRALCLLMAGLMCVSLAGCGSSDSGKETTKAAEGGAAEESKE
                     AGNEESKDGLKVCIVYTGNLGDKSYNDSCNIGAQKAVEDFGIELKSLEGTTAQEWEAN
                     LVAACEGGYDLVIGASSNIADYISKHAPNYPDTKFAVIDTTVDLPNVESISFAQNQGS
                     FLAGAAAAMFTQKTDIEGVNEDNVIGWVGGMDIPVLHDFYVGYEQGAKYIDPDITILQ
                     AFAGTWTDPLKGKELTLAQYEQGADIVMNVASGTGPGILEAAKEAGKYAIGVDLDQDK
                     DQPGHVLTSMVKRVDNACYLVIQSAVEGTFEGGSTQYLTLSEGGVSLTDFSVMKEALG
                     DKFPQDIVDKCEELQEKIVSGEIVVENYEGFGANQ"
     gene            21034..22950
                     /locus_tag="ACZPCR_03950"
     CDS             21034..22950
                     /locus_tag="ACZPCR_03950"
                     /inference="COORDINATES: protein motif:HMM:NF012515.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="HIR1230059.1"
                     /translation="MNIKDIARLAGVSVSTVSKVMNRKDGTISQETREKVLKIARDYN
                     YTPYASVMTPSGKTFLIGVLLRSSTVRTTLNGILERARELGYGVLISDSGSSLEGEKK
                     ALSSFFRNRVDAVLWEAFGTESLQNMSELEKAGIPFLFFNCTLPGSINLDYQGMGYAA
                     ARLLIQNGHQDIACLLSPGSRTDALFEGYKKCLFDHQLPFRKDLIFHGITPALLHRLA
                     SHGATAVLCSHFASALELYERGLILHCKTPEDFSLLSLRDDGRLKTPFPDISSFSIPH
                     RQFGRFLCEQLIRLTEREEGDGSGVLTEATAFSWVPEPDSLSTIGLPFSMLPKKMAVV
                     GSSNVDIYLKVDQLPSSGRVARTSLSAQHAGGKGLNQAVGAAKLGHRVSLITAVGNDT
                     EADMLYETLYKHSVESSGIRKNDSLPTGRAYIFVEPGGESMITILSGANDALRPADLK
                     NSAHLFKDAAYTLISTEIPMETVEEACRLTRSQGGKTIVKPATCGPLKPELLKLIDIL
                     IPNLEELNEICPGPADIKEKAAALLNQGTGTVIVTLGADGCLLCTSGEVKHFPASDFP
                     AIDNTGAGDAFISALASYLLYGFDLEHAIQIAGYAAGFCITREGVVPSLIDKSTLETY
                     LQQKAPELLTIPGH"
     gene            complement(22982..24343)
                     /locus_tag="ACZPCR_03955"
     CDS             complement(22982..24343)
                     /locus_tag="ACZPCR_03955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004220420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1230060.1"
                     /translation="MEPRENVMGTKPVFPLLMSMSIPPMISMLIQSMYNVVDSIFVAR
                     ISEKALTAVSLAYPLQNLILAVAVGYGVGINACIAKSLGARKQEETNRAAAHGILFTL
                     LHSILFVLIGLFLTKPFLGFFTSDPETFSMGCSYTYIVVCLSFGSIFHIYIEKMFQAT
                     GNMIMPMILQAAGALTNIILDPIMIFGLFGFPAMGVAGAAIATVAGQMLACGLAVLLF
                     IKKEKQIHISFKGFQFDKAVAVKIYSIGIPSCIMLSLPSLLVGILNALLTSFSSLAVA
                     VFGLYYKFQSFVYMPENGIIQGMRPIMSYNYGAGYLKRMKETVTCSMLSCGAILAAGT
                     VLFLAVPGPIMGMFGAEGEMLEMGISCLRLISLGFIFSAAGTVFCGCFEALGQGLYSL
                     IVSLIRQLVVIPPLALALSKSIGLPGVWLSFPVAEILAAGIGWILYKKQMRQVKKEIG
                     AEG"
     gene            complement(24504..25145)
                     /locus_tag="ACZPCR_03960"
     CDS             complement(24504..25145)
                     /locus_tag="ACZPCR_03960"
                     /EC_number="2.7.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007717519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0050145 - nucleoside monophosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidylate kinase-like family protein"
                     /protein_id="HIR1230061.1"
                     /translation="MGNRNLIITIEREYGSGGRIVGRKLAEDLGIHFYDDEILKLTSE
                     KSAIGEEYFRLADEKAGNNLLHRIVGRKLDFTEEPVLSGNVTAPENLFRFQSSVIREL
                     AREESCIIVGRAAGYVLDQEEELERLIRIFVCADKVRRVQRVMEVDAIDEERAKRRIK
                     KMEKSRREYYKYFTGSEWHNMKNYDLTINTTNLDLDQTAELVKDYIRLKGFDK"
     gene            complement(25169..25888)
                     /locus_tag="ACZPCR_03965"
     CDS             complement(25169..25888)
                     /locus_tag="ACZPCR_03965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HIR1230062.1"
                     /translation="MKEYTEIQKELIALADEPYRQFHSRLLPGTDHILGVRLPLLRKM
                     ARRLLKEEGAACLDRLTDETYEELQLQGLIIGAVREEAGEKLERIRKFVDKIDNWAVC
                     DAFCGGLTFTRKNQRQVLDFLKPYVSSEREFEARFAAVMLLSWYVDEAHISETLRLLD
                     QIRQPDYYASMAVAWAVSVCYVKFPAVTMEYLARWNTLEKDTYRRALQKILESSRADQ
                     DQKRQIRRLRDSISQRQTEKG"
     gene            complement(25906..27195)
                     /locus_tag="ACZPCR_03970"
     CDS             complement(25906..27195)
                     /locus_tag="ACZPCR_03970"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002593443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005534 - galactose binding [Evidence
                     IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HIR1230063.1"
                     /translation="MMIQETLKKLDTDEAGKLMETLYGAAQAEENKARYRHVAEGFLK
                     EYGDGDVLLFSSPGRTEISGNHTDHNHGKVLAGSINLDCVGAAAKNGTDTVRILSETF
                     HQKFIINLKDLKPSREMAGTIDLTKGILQGFKERGFEIGGFDAFITSNVISSAGVSSS
                     ASYEMLICAMLNTFFNDGRMNVVDYAHIGKYSENKFWNKASGLLDQMACAVGGLITID
                     FKKPEAPAVEKIDFDFSAQDHSLIIVNTGKGHADLSADYSSVPNEMKKVAEFFGKEVC
                     ADIEEKDVIANLAKVRAYAGDRSVMRAFHFFEENKRVEAQVAALKENDFGTFLQKITE
                     SGNSSWKWLQNCYTTADVQEQGICVALALTEMFIAEKKRGACRVHGGGFAGVIMAMLP
                     NDLVDEYTAYIEAALGKGNAYRMSIRPYGAVCVNDLM"
     gene            27505..28566
                     /gene="mnmL"
                     /locus_tag="ACZPCR_03975"
                     /gene_synonym="ytqA"
     CDS             27505..28566
                     /gene="mnmL"
                     /locus_tag="ACZPCR_03975"
                     /gene_synonym="ytqA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006428960.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA modification radical SAM protein MnmL/YtqA"
                     /protein_id="HIR1230064.1"
                     /translation="MQETWPNGRTGRPLQTRWGEKPYYSLDYYLKETFGQKVYKLALD
                     GGMTCPSRDGTLGTGGCIFCSEGGSGDFAESPPPSGSGPGCGTPAAPGRVSPSLPEIE
                     QRIARLDVCGQIERAKARVSSKIKDGKYVAYFQSYTNTYGPLPYLTALFSQAVSHPDI
                     AALSIGTRPDCLPKETIALLKKLNQEKPVWVELGLQTIHEDSARLIRRGYELPCFLDA
                     LRRLKEAGLTVVVHVILGLPGETREDMLETVRFLGRLDNPFIDGIKLQLLHVLKGTEL
                     CRLYEREPFHVMEPEEYFSLIADCIRLLPPHIVIHRISGDGPKSLLKAPLWSGNKRFV
                     LNSIAKTLRETGAFQGEWA"
     gene            complement(28563..29762)
                     /locus_tag="ACZPCR_03980"
     CDS             complement(28563..29762)
                     /locus_tag="ACZPCR_03980"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HIR1230065.1"
                     /translation="MYAGKRLIGGEGEMETEVPFRQEAETEEDIKGKTAETEKAGEKT
                     EEQTERETERPVLQIYTGEENEEKEDTGEKENAEEQTLTRQADTVSLLFAGDIYLSEH
                     VLNAYERGGGIEGVLDSGFLQTIEQADIFMANQEFPFSSRGTPETDKQFTFRLPEEKV
                     SIMQEIGPDIVALANNHALDYGSEALSDTIRVLDEAGILHAGAGENLDEAKALKTIEA
                     GGKTFGFLAASRVFPKGYWAAGPDHPGMLTAYDSTVLLEEIQKAKESCDFLTVYVHWG
                     IERRTEPESYQRTLGQQYIDAGADLVIGSHPHVLQGIEYYKGKPIVYSLGNFVFGSSI
                     PKTMLLQVEVPREGDPALVLLPGTSSGGYTRMVADETEKEAFYRYMEGLSFGITVDEA
                     GRIRQAD"
     gene            complement(29983..30825)
                     /locus_tag="ACZPCR_03985"
     CDS             complement(29983..30825)
                     /locus_tag="ACZPCR_03985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008289 - lipid binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HIR1230066.1"
                     /translation="MTYKILGDSCMDLTEELKQDPHFHMVPLTLQVDHAHIRDDETFD
                     QKRFLELVKEAKDCPKTACPSPEDFKEQFDCEAECIFIVTLSAHLSGCYNSACLAKSL
                     YEEEHGAEAKKIAVIDSLSASAGELNVALCIRDLCEQGLEFDEVVRQAEEYRDQMGSY
                     FVLENLDTLRKNGRLTGLQAFFATALNIKPVMAGDKGVIVKLEQARGMNKALGRMTEI
                     ALKQAGETKDRRLVIAHCNNRARAEYVRDLICSKAQFKDVVITDTAGVATVYANDGGI
                     ILTL"
     gene            complement(30960..31388)
                     /locus_tag="ACZPCR_03990"
     CDS             complement(30960..31388)
                     /locus_tag="ACZPCR_03990"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230067.1"
                     /translation="MEELELLNGLEPVQKALQEFQKTYGEELWNMIFHRGEDPEDYLR
                     AEVLCELAEAVERIQKLAGYLKGTITAEGTLTRREDGGLSIGGRALQPGQEVEVCLYD
                     PMFQAVIWTRASVSMEKRQRLIGLDRDVRQEGLKARIREL"
     gene            31510..31758
                     /locus_tag="ACZPCR_03995"
     CDS             31510..31758
                     /locus_tag="ACZPCR_03995"
                     /inference="COORDINATES: protein motif:HMM:NF024835.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1230068.1"
                     /translation="MIVYDKLWTAMKEKGISQNHLYKYYNVSRAQIYRLKHNEVVYTS
                     TLNMLCNILGCDDISDIATFVPDHPGDEGYREPAAGEK"
     gene            complement(31924..33924)
                     /gene="htpG"
                     /locus_tag="ACZPCR_04000"
     CDS             complement(31924..33924)
                     /gene="htpG"
                     /locus_tag="ACZPCR_04000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HIR1230069.1"
                     /translation="MAKTGSLSINSENIFPIIKKWLYSDHDIFYRELISNGCDAITKL
                     KKLEMMGEWEKPEDLEFQIQVTVNSEDKTIIIEDNGMGMTEEEMDEYINQIAFSGAQD
                     FLNKYKDKANEDQIIGHFGLGFYSAFMVADKVTIDSLSYRADAKPVHWESEGGTEFDM
                     KDGDKETVGTKITLYLNEDSTEFANEYRAREVIEKYCSFMPVPIFLNNAKAEPEYETI
                     EKDELNEKDTIVETIVEEAKTEEKENEDGTKETVEVSPAKEKYKILKRPVSLSDVNPL
                     WNKHPNECTEEEYKAFYRKVFMDFKEPLFWIHLNMDYPFNLKGILYFPKINMEYESIE
                     GTIKLYNNQVFIADNIKEVIPEFLMLLKGVIDCPDLPLNVSRSALQNDGFVKKISDYI
                     TKKVADKLSGMCKTDRENYEKYWDDISPFIKFGCLRDEKFAEKMDEYIIFKDLDGKYL
                     TLKDYLEAAKDKHENKVFYVTDEKEQSQYINMFREEKLNAVILTHNIDNPFITHEEQK
                     HENVKFLRIDADVNEIFKEEVKEEDKETLENQAKTLTETFRKALGNDKLEVKVEKLKN
                     ESVSSMITVAEETRRMQEMMKMYNMYGMDPSMFGGTGEVLVLNANNSLVKYVLEHTDG
                     EKTPVICEQLYDLALLSHGTLSPERMTKFIARSNQIMTELAE"
     gene            34210..35388
                     /locus_tag="ACZPCR_04005"
     CDS             34210..35388
                     /locus_tag="ACZPCR_04005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="HIR1230070.1"
                     /translation="MKYKTKTLKYGLAGILSLAMAAAPAGTCLPGFLPAQALTVYAGP
                     AEEATVSSDEPTGPAALGQTQGLSASNYYNVRLSDPIVKPVDKYSYEQMDRDIQALKN
                     RYPNQMTVNVIGQSADGRNLYDIIIGNPSASEHILFQGAIHAREYINVPLMMQQLEYL
                     LACQNTGTFEGKSLSEMLGQTAVHFVPLVNPDGISISQSGDGAIRSPELKAQIRACYE
                     LDTAEGRTTADYDTYLRRWKSNGRGVDLNHNFDAGWNTLNTVGHPSSTDYKGTSPLSE
                     PESQALAALTDQYPFAVCINYHAMGQVIYWDTENNRQTSSSKELAELVSRHNGYQILG
                     SKGVGGYKDWLQQREKSIPGITIEVGKSACPVNFSEYETIREQNEAVPGLIIQYVISH
                     "
     gene            complement(35519..36016)
                     /locus_tag="ACZPCR_04010"
     CDS             complement(35519..36016)
                     /locus_tag="ACZPCR_04010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002600978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5721 family protein"
                     /protein_id="HIR1230071.1"
                     /translation="MVSLQIEEIKEFTRQLFIGTTFDHFLLREAQIVTFNSFQIDGRI
                     RPDYYSAEEREEQGIEGFSAWLALRPFCFSLIKGKRLPESFHIVLQLSGKAQEAFLRD
                     RQTGFASSEVNGLYLNIRYEDKRLSCVTGTSVSRFTLDKTLEHEWDGAVKEFLKKKNI
                     PFEEK"
     gene            36400..37695
                     /locus_tag="ACZPCR_04015"
     CDS             36400..37695
                     /locus_tag="ACZPCR_04015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HIR1230072.1"
                     /translation="MEQYKNDLNGLTELLTAGVSPLHTIRHSMNLLESRGFTELSLDK
                     AWALEPGKGYFVNAFDTTLIGFTVGEDAAEHPSFRIASSHTDWPCLMVKPSPEISAEG
                     YAKLNVAVYGGPILSTWLDRPLSLAGKVCTVSEEPFHPQVHLVDFKRPLLTVPNLAIH
                     FNREVNNGVALNPQIDMQPILAMLDETLNKDSFFLDLVAEELHVNKEDILDYQFYIYN
                     CDMPQTLGIHNEFLSAPRLDNLTSVHACLSGLMESSRKRGICVAALYDNEEIGSSTKQ
                     GAASPLTDRILEKIYLSLGYSRSDFLDALFGGFLLSLDVAHAYHPNKGEKYDPKDRVL
                     LNDGVALKLAVNQAYATDASHVSVIEGICRAHEIPYKKFSNRSDVKGGSTLGSISSCL
                     LTMPAVDAGVALLAMHSSREMMGIKDQWALAELTRQFLA"
     gene            complement(37881..39335)
                     /locus_tag="ACZPCR_04020"
     CDS             complement(37881..39335)
                     /locus_tag="ACZPCR_04020"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 protein"
                     /protein_id="HIR1230073.1"
                     /translation="MDEEQIRQRRRRSRARSRRRRQEEKRRRVLLLVLAVLAAILLAA
                     AGAVAGGRKSVREEAGSIRPELLPGDDTGIGLGGKPEEAEAAENSRENGESDQKGSQE
                     EAQKETLKEEQKETQKEAMEKGDSEAEKMAAELLSSMTLEEKIFQLFMVTPEALTGYD
                     EVYMAGEATKDAIWERPVGGIVYFSQNLKDKDQTREMLAKTARYGEERSGLPPFLAVD
                     EEGGQVARISGKEGFSLEAFPDMSKIGASNDEAKAFEVGETIGKYLADLGFDVDFAPV
                     ADVLTNQDNTVVARRSFGSDAEIVSRMVSEEVKGLKKHGVSPVLKHFPGHGGTAEDSH
                     ETKPVLHRTLEELSETEFLPFAAGIESGADFVMAGHIGVPEIEEDGRPAVFSKTLLTD
                     VLRKQLGFEGIIITDAMNMGAVTESYDSGEAAVAALSAGADMILMPEDFDAAVQAVKD
                     AVEKGALTESRIEESAMRILALKAEKNMERETAR"
     gene            complement(39338..40330)
                     /locus_tag="ACZPCR_04025"
     CDS             complement(39338..40330)
                     /locus_tag="ACZPCR_04025"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HIR1230074.1"
                     /translation="MSRRKKWRIRSAAAVLISLPLLLSGCQKTESILAGMGGEKGYER
                     PEIMIAAMSQKNTCEELCTGQIWSAQVDESGKTFEEYTKEQLKSFMDELKILTLLAKE
                     RNISLTEEEASAMAKASEEYLAALTPEDISYMGVDETSVNTMFHDYCLANKTVEELTK
                     DLDMEVSDSEAKVIQISEVRTADREAAQAVSDSIEAGASLEKAAASEGLEVSSAKIGR
                     ADRGEDYDYAAFALETGEVSKVVEDQGEYCVIRCDNDYDQEATAQRKEQIYDARRQKA
                     FQDIYSGFKEGITLNDSVKDWEALTLGGEAHAENADFFEIYRKHTLIQTEQLGE"
     gene            complement(40365..41153)
                     /locus_tag="ACZPCR_04030"
     CDS             complement(40365..41153)
                     /locus_tag="ACZPCR_04030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HIR1230075.1"
                     /translation="MIKLIVSDIDGTLVRDGENKINQELFDVIMRLKREKQIHFAAAS
                     GRQAASIEYTFAPIGKEIFYIAENGAYLGCLGRNLFLYPMKRADAVELIEDIRKNPSL
                     DLVISGSSHAYMETKNQEFINWVRDGYHFDVVQVEDVTKVDDSIIKVAAYKKSDIQAE
                     AGAFWDKYKDRMKITISGDMWMDCMALEVNKGEAVKTLQESLGIAPEETMAFGDQLND
                     VEMLNRAYYSFAVGNARPEVKQAARFQADTNVRDGVLKILKTLL"
     gene            complement(41150..41776)
                     /locus_tag="ACZPCR_04035"
     CDS             complement(41150..41776)
                     /locus_tag="ACZPCR_04035"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007860414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009146 - purine nucleoside triphosphate
                     catabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Maf family protein"
                     /protein_id="HIR1230076.1"
                     /translation="MKEQNKCGSQIWKVFSFPVVLASASPRRRDILNQIGIEPVIMPS
                     QVEEHITSSDPEQIVKELSWQKAEDVYRRCQKELGGRFAVIGADTIVAADGEILGKPK
                     DEEDAKRMIRLISGRVHQVYTGVTILYEGRTVTFAEKTDVSVAPMTEREIEEYISCGE
                     SMDKAGAYGVQGVFAAFIEGVNGSYTSVVGLPAGRTYRKLRELAEGIE"
     gene            complement(41859..45095)
                     /locus_tag="ACZPCR_04040"
     CDS             complement(41859..45095)
                     /locus_tag="ACZPCR_04040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HIR1230077.1"
                     /translation="MYIADLHIHSRYSRATSRDLTPEQLDFQARKKGIRLLGTGDFTH
                     PAWREELKEKLIPAEDGLYRLREDCVLSPEAGAEEERTRFVVSGEISSIYKQDGKVRK
                     VHSLILLPGLEEAEKLSARLEAIGNIHSDGRPILGLSCHDLLEIMLETCPEGMFIPAH
                     IWTPHFSMFGALSGFDRAEECFGELTPYIHAVETGLSSDPPMNWQLSALDRFQLISNS
                     DAHSPAKLGREANLLSGDLSYYGLKQAVETGEGLDGTIEFFPEEGKYHFDGHRKCHIC
                     LSPAEAEAQGGICPVCQKRLTMGVSHRIAQLADRPEGFVPEKAKPFESLVPLLEVIAA
                     STGRSAAGKKVREEYETMIRKLGTEFAILREVPIEDIKRECGYLTAEGIRRLREGKVE
                     RLPGFDGEYGAVRLFTPDEIESPEGQMSMSGLFETKTDSEAGNRTASGCEKHEREQSG
                     EENFSAKALAGEPDKRADRPADFLSLLNEKQREAAELPSSCLAVIAGPGTGKTGTLTA
                     RIKCLIEKRRVKPSEITAVTFTNQAAGELRERLKRELANKRGQSLIQTGTFHSICLKM
                     LEAAGEKADLADPLELSALAEEILEEESKPLRPTEFLRRVSRKKTELALAQEMSEKTG
                     EKEENSFQKAFDRYRTAMEAQGWLDFDDLLIRTVSLLRENCPAICRFCSHFRYLLVDE
                     FQDISPLQYALIREWNKEGRELFVIGDPDQAIYGFRGSDAECFKRLLQDIPETKVIAL
                     QENYRSTEPIVKAACSVISHNPGGERTLAAKAGSGDPVRVVKAGGRRSEGIFTAREIN
                     RMIGGIDMLDAQERGTFLEKGPRSFSDIAVLCRTNRQAEEMEECLRTEGIPYIVTGRG
                     TFLEADTVREAEGFFALLTEAGEGMEETAFKRTVQFLNRRIGGEKLLQLLEKYRPMAG
                     KKPADLLKAWMGDRDLKEDEPLARLASMAMFHKTMKDFLFTLFWGREGDLKRCGKKRY
                     AADAVSLMTLHASKGLEFPAVIIPGMRKGSLPLETEQAEEERRLFYVGMTRAREELIL
                     VTSGEPSPFLEELPEAEIQNEELAGTPEARARQMSLFDFFPSGEMPSA"
     gene            complement(45172..46413)
                     /gene="fliB"
                     /locus_tag="ACZPCR_04045"
     CDS             complement(45172..46413)
                     /gene="fliB"
                     /locus_tag="ACZPCR_04045"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF038110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin lysine-N-methylase"
                     /protein_id="HIR1230078.1"
                     /translation="MIVKPSYCGSFQCIASRCRDNCCIGWEIDIDEETDQFYRTVKGE
                     FGKRLEDGISREGTPHFRLKGEQERCAFLNDSNLCDIFIHLGEEHLCGICREHPRFYE
                     WYEEIPGLLDWTETGLGLCCEEAARLFVSESGPLRLTVEWESEEERRQWEKAVKQPRT
                     EEAAYLLSILSAREAAFQILEGGGALQENEEDSSPSRSGLADRIVQFLKLAGQIQECL
                     DDTEELEETAGKIRRLSEQSSERFNAENAEYSEKSVKNPELQEERAAYFRQLFAVLRQ
                     LEPMGEFWTKLLDELDCSVEELLSLAAARQEDGTELYERLVEYGVYRYFGKCAFDGDA
                     YSRAGLAVLFAVLARLTDLNAVLRQGGLSREAQAEHIRLLSKEIEYSEENLEFLQNAF
                     WEEEIFSDQGLSEAVKALWGV"
     gene            46635..47309
                     /locus_tag="ACZPCR_04050"
     CDS             46635..47309
                     /locus_tag="ACZPCR_04050"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007713078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA];
                     GO_process: GO:0098869 - cellular oxidant detoxification
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HIR1230079.1"
                     /translation="MEHLEGNRLPLIGDTAPAFQALTTKGTVHFPDDYQGKWVLFFSH
                     PSDFTPVCTTEFMTIASMAEEFKALNTELLGLSVDSLYSHIAWIRRIEELSWNGIEQV
                     HVDFPVIADLNMKVSHLYGMLQPNVSSTQAVRAVFIIDPNAVIRAIIYYPLNLGRNFD
                     ELKRIISALQKADADHCSTPANWRPGDDVILPSPVTCDEAKERAEHPGENEYSLDWFL
                     NFRKEK"
     gene            47433..47996
                     /locus_tag="ACZPCR_04055"
     CDS             47433..47996
                     /locus_tag="ACZPCR_04055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006778992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HIR1230080.1"
                     /translation="MIKKQLIACFMAASLAAASLTGCSGSPSSNETSAQETVANVSLD
                     DILKDIKEAYGENYVPDSSVDEQMLSDIIGLSPDLYESYVAEMPMISTFVETFIGVKA
                     KEGKGEEAEKALNAYRDQLVNDTMQYPMNVAKIQASQVIRHGDYVFFVMLGAPSDEAM
                     EEGDEEALKSAAENNQIAVDIIDGYFK"
     gene            48000..49424
                     /locus_tag="ACZPCR_04060"
     CDS             48000..49424
                     /locus_tag="ACZPCR_04060"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family O-acyltransferase"
                     /protein_id="HIR1230081.1"
                     /translation="MVFSSLLFLFRFLPLFLALYFAAPKRFRNSILFLGSLIFYGWGE
                     PVYISLLLFSTLVDFVHGKLAGSFREKGNMTAAKWVVASSAAINLGLLIIFKYTDFFI
                     RSFNELTGSSIPLLGLALPIGISFYTFQTMSYTIDVYRGQAPVQNNLISFGAYVSMFP
                     QLIAGPIVRYQDIARELNSRRETVAQFAFGVRLFIIGLGKKVLLANQAGALWTEITAI
                     LPGDRSILMVWMGILAFSFQIYFDFSGYSDMASGLGHMLGFYFPDNFRYPYISKSITE
                     FWRRWHISLGTWFKEYVYIPLGGNRKGGLFQIRNILIVWLLTGIWHGAALNFLLWGIY
                     FGTLLLLEKFILKRWLERLPAWIQHGYTCLLVLLGWVLFAFEDMNAGFVYLTQMAGGA
                     DLPLWNDRTLFLLWGSLILLLACTIGSTPLPAAAAKKLCSDIQGKLKTAGLVLEPLFL
                     GLVCFLSVAYLVNATYNPFLYFRF"
     gene            49446..50615
                     /locus_tag="ACZPCR_04065"
     CDS             49446..50615
                     /locus_tag="ACZPCR_04065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006778994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHHW family protein"
                     /protein_id="HIR1230082.1"
                     /translation="MKKQSLYPAVVTGLFCAFLGCGALLSVLMPKKSFSETENRYLAQ
                     LPIFSWERLADGTFGTDYEKYLSDQFPFRDSWIGVKTAAEQLQMKKEINGVWLGADQF
                     LFEALYPEDIDKVLYEKNVKRLSAFAQAQEELLGSSHVRIMLIPSASQILTEQLPAFA
                     SPFQQNQLVTDLENSGISSLMVPVQSALASAHSETHPSDRELYYRTDHHWTSPGAYVG
                     YKAWADSMGFKPLSPSDFTVETVSGNFLGTIHSKLNLPIKPDSIELYRPLEEPEWSVY
                     YDGSSEPSHSLYSMKALQTRDQYRVFLDGNHGWTKIENPAQPSDKKLLILKDSYAHSF
                     APFAALHFGETHMVDLRYFNGKISSFIRDQGITDLLVLYHMPGFMKDANISKLGW"
     gene            complement(50631..51830)
                     /locus_tag="ACZPCR_04070"
     CDS             complement(50631..51830)
                     /locus_tag="ACZPCR_04070"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="WD40/YVTN/BNR-like repeat-containing protein"
                     /protein_id="HIR1230083.1"
                     /translation="MSWKIEEWQNKKQISFKHNNIFESGIEGILADLDEALGLPEELY
                     ISGQFQTGFDETGTIQELDTLIYGKDKNGQTNTYLIDYDADDGETMTVWTDQNTDAAY
                     DSDKLLSPMLEILKKADWEGQVKVWSDTLGEQQIYELLYLGRRAFHSSEGLEYVSGDA
                     DGDGTETGTGSFHMLQNGGEIAGFEVSLHIPEESGITPVRYIMEPEYISQAELAQENT
                     VLQAEKAKEEDGWTIDRSTETMYFFLNDQKGWRLSVAGAAAGSRFYQLDQTTDGGSTW
                     NCANADPFGGQIGAAEGLQFFDENFGAAGLTGASRSHSSIYLTRDGGVSFEMTELPFD
                     QVTELPKTAEEYGLAMEDYDYLSMPKQEGEKLLIRVTSEEAETDGFMFQSEDQGVTWE
                     YQGVFQK"
     gene            complement(52237..52878)
                     /gene="uppS"
                     /locus_tag="ACZPCR_04075"
     CDS             complement(52237..52878)
                     /gene="uppS"
                     /locus_tag="ACZPCR_04075"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl diphosphate synthase"
                     /protein_id="HIR1230084.1"
                     /translation="MRIPKHIGIIPDGNRRWAKRAGLEKQDGYAHGLKPGLDMLKLAK
                     NAGVEEITYYGFTTDNCGRPKEQVEAFSKACVEAINWITAESVSLLVVGNQESPAFPK
                     ALLPYTRRTDFNGGGIRLNFLVNYGWEWDLAKLKAPGSRRMSICRQLESHDISRIDLI
                     IRWGGMRRLSGFLPVQSVYADFYVVDGLWPDFQPEDFSKALEWYQKQDITRGG"
     gene            complement(53033..53701)
                     /gene="deoC"
                     /locus_tag="ACZPCR_04080"
     CDS             complement(53033..53701)
                     /gene="deoC"
                     /locus_tag="ACZPCR_04080"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: protein motif:HMM:TIGR00126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HIR1230085.1"
                     /translation="MKINQYIDHTYLKPFASEQDIIETCREAKEYHFASVCVNPCNIR
                     LAAQELGESEVKACSVIGFPFGTHTTAVKLFEAKEAIRNGAEEIDMVINIGKLVEGNE
                     AYVEEEVQALTDLCHQHRVIIKVIIETCFLNEAQIAAMCRIVENTGADFIKTSTGYGS
                     RGADFKDIELFRKYLKKPAGMKASGGIRTLEDAVHYIELGCKRLGTSNGAAIVNRTEG
                     KESY"
     gene            complement(53722..55032)
                     /locus_tag="ACZPCR_04085"
     CDS             complement(53722..55032)
                     /locus_tag="ACZPCR_04085"
                     /inference="COORDINATES: protein motif:HMM:NF024808.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIR1230086.1"
                     /translation="MKKGTAIGLGLLMAGSLMTGCSAAKDEAASTSEGGVVSEANEKT
                     DVVFWTSMSGGMGETVDKIVKDYNESQDKVHVTVEFQGNYYDMAAKLQTAVTSGEAPH
                     IAQLEMGRTKMFADYGVLQDMTEPAREAGLDPEMFYDGLMDCCDWGEGLYALPFNRST
                     PMFYYNKDMFEEAGLDPETPPQTWDELREYASKLSIPNQRWGFEMPIDAWFYEAFIMQ
                     GDGRILNEDETDIGFNNETGTKPLALWKSMIEEGVMKAPPGKEYNSYEAARSDFAAGI
                     TGMIVTSSGDLGTLTNSCEFEIGTAFLPKDKRFGVPTGGANVVMLAGHEEDTEAVMDF
                     LKYLTSPDIAAYWSVQTGYVPSSEAASESSVYQEFIADNAAAKTALEQMQYTDIPRPI
                     NEDYPQIHSEIMMTEIQRCIEMEGYTPEQAVAAISNQTKALLEK"
     gene            complement(55055..>56319)
                     /locus_tag="ACZPCR_04090"
     CDS             complement(55055..>56319)
                     /locus_tag="ACZPCR_04090"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013799.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HIR1230087.1"
                     /translation="SLFDEDMEYLKTLPNFKKILERGAYAQGGMRSVYPSFTYPAHAS
                     IITGTWPEFHGIYHNEKLDVGNPAPDWFWYHKDLKVPTILDLAHRQGFTTACIGWPCM
                     GANPEIDWLVPEIWPENDRVDPRDILKTACSENMFGENGILERHWHKLRRTTQPFMDQ
                     MMVGCACDIIRRYQPDVMFIHLAHLDHTRHANGIQGSAITQAVIANDDWLGRLMEAAM
                     DAGIYDDTNFAVISDHGHLPVKQVFHPNVLFVQAGLIRVGEDGTIRDWDAYCNSTSLS
                     CQIVMKNPDDSVTRKKLEELLYKMRATPEYGIESVFHKEEVRREQHLAGEFEYVLEGQ
                     NTSFGNRWTGTVIERPDNSDYKFSVASHGHLPSKGPQPVFMMAGPDIREGVIVERKCI
                     IDEAPTFAKLLGFEMPEAKGSAIEELLK"
BASE COUNT        12575 a        16256 c        12020 g        15468 t
ORIGIN      
        1 ttctcaatat tcaattttta aagcagccac cgaaagatgg cttgtttgtg atgcgattaa
       61 ggaaatggat accccctact tctcattttc aatctttcct cctgataaat aataattaaa
      121 atgcaagacc gctgttttca gccgccgcta ttttcttaaa atagaggtct ctgtgatttc
      181 gatttttcct tcctttaaaa ggtgtcccac cgctctctta aacgcgtttt tgctcaggtt
      241 gaactccctc ttaatcacct ccggagacgc cttgtcatta aagggaagcg ctccgtcgaa
      301 ctcgtcaatc acctttaata tttcctctgc atccttgtcc atctgcagat acgccttttc
      361 gcggcagctt aaatccagct ttccatccgg acggattttc gtaattctgg cctctatcac
      421 ctctccgata tggaaggggc gaaacgcttc ttttgccgga atcataccgt aatatttgtc
      481 atccacagcc acaaaaacgc ccagtctgtc gttgatctca tatacgcgtc cctctacctt
      541 gtcgtccttt tgatatcctt ctgctgtctg aaggtaagga tataccttca tggtcgctgc
      601 cagacggctg ctcttatcca catatagagc ggcaagacag tcatctcccg gccgcagcct
      661 ggccgtctgc tccttgaacg ggagaagcag atccttctcc agccccatat ccaggaacgc
      721 tcctattttc gtaatctcct ttatcttcaa aagcgcagtc tgtcctgcct ccagcttcgg
      781 ctctgctgtg gtggcgatca ggcggtcctc agaatcctta taaataaata cctgaagact
      841 gtcccccagc ttcgtcccct ccggaacctg ttttttcgga agcagcaccg atgcctccgg
      901 gtgcgccttc tctcccaggt acactccgaa ttccttttct ctgagcactt gaagctcctg
      961 ttttctgcct aattcaatca tgtcatccgt cctttctttt ctcctgtcca tcccggctgc
     1021 cagagcagct ccccttcagg tacatatttg caaacggcga tccatcttcc cctgtaaggg
     1081 aaactgtata accgtcttcc tctctgctga tgcgcggcac cattttgtcc cccagtacag
     1141 ccgccttctt atattccacc cgaagctcct gtatctcaaa atctcccggc agaaactctc
     1201 tggcaatctc tgcatactgg gcattattga catgcagatt ggtgtccaaa tgatgtctgg
     1261 ctgcttctac cggcctctcc tcccagtaat gctccgagag gcgtattttt ttcggagctt
     1321 ccggcatcgg caggggggct tcgcactccc cgtagccccg gatctcctta ggcgtcactc
     1381 tggcgggaca tcccttttcc agatcataga aaaaccagca ggaatctgcc ttgactatca
     1441 ctgctccgct ctcgtcccgg atcagaaaat tcctgtagcc gtaaatcccc ttaaagccat
     1501 ggggataggt ggatatctga attttctccc caagggatgg gtatctgtca atcacaatct
     1561 gccaggagtt cagccaccag gcccgctttt cctcttccag ataggaaatc cccatgtgca
     1621 gatcctcaga ctggaaggtg gaacagtcct ggaaataatt cataatgcct gttaccgaca
     1681 gtctgcctgt ctcatccgtc tcactgtatc tgactctgct ttcaaatgta tacatctctt
     1741 cacctcttgt actctcctat tatatcggat cccgcctctc ttgtccatgc cggctctggt
     1801 actgtttttc gagttatttt gggattttca cgttttttat atttttttat attttttcaa
     1861 aaaaagtgtt gacgaaatga ttttcatgtc gtataataac acctgtcgtt ggggtatcgc
     1921 caaatggtaa ggcaacggac tctgactccg tcatttcaag gttcgaatcc ttgtacccca
     1981 gttaaatggg aaaagacatc agttttctgt caaacagaaa tctggtgtct tttttgtttt
     2041 ccagtgaaaa tccgattgga agagctcgaa tcccccccgc catagaaaag gagaagcagt
     2101 tcagcgactt ccaattggag cgtgaacgct tctccttttc tattataccc ctatcttatt
     2161 ttataaacat cgcatcccca aagctgaaga accgatacct ctccttcacc gcttcctcat
     2221 aggctgccag aacgtgttcc cggcctgcca gagctgatac cagcatgacg agagtggact
     2281 ccggaagatg gaaattcgtg atcaggcagt ccagaatctt aaactgatat cccggataga
     2341 tgaaaatatc tgtccagccg cttcctgcct tcagaattcc attctcatcg ctggccgact
     2401 cgatggtccg gcagctggtg gttcccacgc agatcactct tcctccgtcc cgtttcgtct
     2461 ggttaatctt ctctgcctcc gactcctcta ccatgtaaaa ttcagagtgc atatgatgat
     2521 ccagcacatt ttccaccttc accggccgga aagtgccaag tcccacgtgg agggttacat
     2581 gggcaagctt cacacccttg tcctcaatct cctgaagcag ctcctttgta aagtgaagtc
     2641 ctgctgtggg agccgccgca gagccctcgt gtttcgcgta aaccgtctgg taacggtttt
     2701 tgtcctgcag ctggtgcgta atgtacggcg gcagaggcat ctgtcccaga cgatctaaaa
     2761 tctcctcaaa aattccatcg taggaaaact ggatcagacg gtttccttcc tccactacgt
     2821 cgatgaccgt tccctttaaa agtccgtccc caaagcaaat cacggttccc ggcttcgcct
     2881 tttttccagg ctttacaagg gtctcccaga tatcgttctc tctccgtttc agaagcagca
     2941 cctctatctt cgcattggtc ccctccctgc ttccgatgag tcttgccgga atcaccttcg
     3001 tgtcgttaat gaccaggcag tctcctggat tcagatatcc taaaatatcg cggaatttcc
     3061 ggtgggttac ctctccggtc tcccgatcca gcaccagcag cctggaggat gcccgatcct
     3121 ctaacggatc ctgggcaatc agctcctggg gcaaatcaaa gtaaaaatct tttacattca
     3181 tgtttattca gcctcttttc tatgggttta tatcatttta ttcttcatcc tgcatgtatc
     3241 cagggccgtt ttccataaag agaatccgcc ctttcagctc ttcgtctgca ttcatggccg
     3301 cttccttggc ctcatcaatc tgctttccca aaagcacagt gtcttcgttt cggttgacag
     3361 cctccagata agcctccagc tccggcgtct tctccccgtc aaaaattctc cactgcccgt
     3421 cactgcactt ttccacataa acttctacta aagacggcgc aggcgtgtcc accccggaaa
     3481 aacgcacgtc gtaggaaaca taagccacat aggcgtcttc cgtcagccct tttgccgtat
     3541 aacaggaaat attttcatat ccgtcgatat actctctctg tttctcaaag gactgtctga
     3601 actgctcctc ctgagaggta tcctgggagg taaacagatt cataaacgtg tccatatcgc
     3661 actccgagac cgcgcggaaa tattcctcca tcagctggtt aatctcatgg tgggcatcct
     3721 tttccagaat gcttccccca aagtcatagt gatactcttt tgtgtccggc tcaattacca
     3781 cgtcctgttc cgcctctgaa tccagctgcg attccggttc cggctgtcct ttatttcccg
     3841 cctctcgcag aaatcccgct gtcagaagca cagctgccag cgccagaatc aaaagaggca
     3901 cagctaagag aattccaaat ctgcgaagct ctctgtccga catcggctgt ccggacggct
     3961 tttttctgct tcttcccatt tttctgcctc ctgtcttttc tctacgtatt ttagcaaaac
     4021 tgcagataaa aagcaaataa cttttcctgc aaaattactt gcttttttgc acaaactata
     4081 gtagaatact attaatgcgt ctgtagctca gtggatagag caatggcctc cggagccgtg
     4141 tgcgtaggtt cgattcctat cagacgcatt tttttgatcc ctgttaaagc tggcagacgc
     4201 caggtgaaac agggatttat ttttttccgt tctctgcttc tttcccattt ccggctcttt
     4261 tctttcctct tctgtgaatg cagagtgctg ccaatatcgc tgcagctgca gcccagacgg
     4321 ctgtgtttga ataggcgtcc accgtttcca tcacccgctc ccaggaagct ccggccgccg
     4381 cgccggcgca gatcagaacc gtattccaga tcaggcttcc cactgtcgtc agaaacagaa
     4441 aaggcgccag cgccatttga gccattccag ccgggatgga gatcagactt ctgataatcg
     4501 gcacacaccg acagaaaagc acagctgctt ttcccctttt ttcaaaccat tctgccgcgt
     4561 cttccacatc ctccttctga aaatggagaa gcgttcccac tctgcctccc aggaagcgtt
     4621 ccagacggct gggcgtggcc aggcgtccgg ctccatagag aaccacggca cctgccacag
     4681 aacccgccgt agccgccgct atcgcctccc ccgccgtcat ggcggtgtag gtggtcataa
     4741 atccgccgaa tgttaaaatc acctctgacg gaatgggcgg aaaaagattt tcaatcagga
     4801 ttaataaaaa aattccaata ctgccccacg aatccattac ctggaagact gcttccctca
     4861 tggctgatcc tgccttatat gtctgtttcc tcgattcagt ttatacagac agcttattca
     4921 ctatgcccct gttcttctgt ttttcctgcc cccttctctg cctcttcttt tatttctcct
     4981 gcttcgtctt ttatttttcc tgtctcttct ctttcttctg ccagactttc ttccgttaga
     5041 ggctccacct ccccgatcag aaactcggct cccctgctgc catcctcata agtgcgtacg
     5101 acaatttcta tcggagccgt cactgcgagc tcatccccgt aatacggctt tctcccttct
     5161 gccgaaatcc ctatttcagt ctccaggcgg gctggattcc caggcttaaa gcagacccgg
     5221 tcagagatat tcagacctgt aatttcagcg tcctttgccc agcttaaatc ggcctttccc
     5281 agggcctggc catcctggcg cagcagcgtc ccctccggct ctcctttttg aaagcttaag
     5341 gaaaaacgat tggccatctg gctcagataa tcctcctcct caaaacaatc cgccgtcatg
     5401 gttcccgatt cgcttcttaa aaacacccag agtgaatctc tctttctgtc ttttcccgtc
     5461 tccgcgtgaa aggacacggt aaacatcgat ccgctgccgt ctgacactgc gtccggcatc
     5521 tgatgggagt ctgacatgta gacaagctcc ggaaaatagc tgacgctgtc gccgcattga
     5581 atcatcacac cctggaaggg cctttccgga tccagatagc cgtacatggt tacctgttcc
     5641 ctgggaaact cggccagcac gattccccag ctcgtctttc cctcctcaag ctccttcttc
     5701 tccgttccag acgtttccca gtcctccagc tcctctgctg tcacaagctg cagatgatca
     5761 gggctggtca aataaaatct ccggctgaat tccagatctt tttcctcttt tggggtctcc
     5821 tgcagttcct gccccggctg cgccagagtc ccagacacag cgcctgtccc ggagctgagg
     5881 ccgcagcctg aaaggcctga cgaaatcgac aggcacaggg caagcagcga acatcctgcc
     5941 atccgtttct tccaattctt cctgaaagtt tcctttcttc tgtcttctct ttccttcatt
     6001 cttctcttct atcctaaaga cgccggggac gttcccttct gtcatactct gatgtctcag
     6061 ggcctccccg gcgcttattt tttacttttc ttctaatagg atacttccgg aagaatacag
     6121 ggtcaatttc cttttcctta cgttttcttt agttttctat ttcctaatta gaaattattt
     6181 taaaattttc taaatttatc catcaattca aaagattaat caggaagtat tccatctgaa
     6241 atctcttttc ctctctgact gcccgctcga tctgctccaa aacctgatcg gaatgttcga
     6301 tttgacggca gaaacgtgat acaagcgtta taaacagctc ttccttcttt cgttctgcct
     6361 tctcctcaca ggctgcggct ccgtatgcct cccgtatgca gagtacaaag aacaggacaa
     6421 attttacttt ggaatacagc tccccgtcgt acacagctcc cggcacataa acatagagaa
     6481 ggtggatggc cagattttca taccagagct ccaggtctga tccttcttcc acgtcccgat
     6541 caaagcctgc tgaaacgatc cgcctcctgt agtcctcata gccggcttct gtccggtaca
     6601 gaagatccat ccacccggaa atcatagaac caaatcccgg ataaatgtca ggcagctccc
     6661 ccaaaactcc cagaaagcct gccatggaat cataccgctc ctccggcctg ttttcccact
     6721 cagaaagctt ctttaaaaaa cgctgacagc cagggggagt ctttaaaagc tcatacctgg
     6781 ctaaacgccg gctgatcctt ctgaggctct cccccctatc ctccgtttcc tttcgaaacg
     6841 cgcgctttac agaaggctgc agatcatgag ccagggtcaa aatcatggcc agcctgtatt
     6901 taagcggcac cttcccctct gacagcaggg aaaacatcag cgttcttgtt ttcagaaggc
     6961 tggacagaaa tggttcttcc tcccctgttt ccagaacgta ctcatgaagc ttaagaccat
     7021 ttcttcgtct taacagaatc cccgcggctt ccgggcagga cagggacaga gaccattcac
     7081 gtctgctccc atagtcttcc gcgtggcggg gatagctgcg gcaggtacgg cacagatatt
     7141 tctctcccag atccctgtga atccggcaca ggccgtcctc caggaaaggg cagcctgtct
     7201 ctttcatccg aatctttttt ctcaggaaat caatcccccc gccaaagtca aagccggctc
     7261 tcttaagaga tctgtacctt cgcatagcct cctgattgac cggaatatcc cagcccctgc
     7321 agcaggtttc cgggcaggcg gggccaatgc agcgaaattc cttatagtat tccggaactg
     7381 cggctgtctt tctaagcttt cttttttctg tctcctgatc ccttttccag tgtttcaaag
     7441 cttccttcct ttctgctccg cctcttttcg gcaggctcac agctgccgcc tttcctgctc
     7501 tgcgcctttg ccccgtctgc ttcccgcact gcaaacacgc tttctgttcc gtccttctgt
     7561 tctgtatcca ggcggcacgt tccgcccttt ttcaggcttc cgaacagaag gcggtccacc
     7621 agcagaggtt tgatctccct gtctatcacc cgtcctaatt ccctggctcc gtactctctg
     7681 ctcactcctt tttcagccag cagatccaga gcctttctgg tgtaggaaaa ctccacctgc
     7741 cggctggcta aaagcgctcc aagctccaga agcttctttc ccgctaccgc cctggcagtc
     7801 ttctttccaa tgctgtggaa cacgacaatt ttattcagac ggtttctgaa ctccggctgg
     7861 aacacccgct tcacctcgtc gagaaccgcc tcgtctccat ttcgcgtctc ttcctcaggg
     7921 ctccccgaaa atccaaggcc cggctttgcc atcctgccgg ctccggcgtt ggaagtcata
     7981 atgagaatca catttctgaa atcagccttt ctgccctgat tgtcggtaag agtcgcgtaa
     8041 tccatcacct ggagaagaat gttgtaaata tcaggatggg ccttctctat ctcgtccagc
     8101 aggaggacag cgtggggggt cttcctgact gcctcggtaa gcagacctcc ttcttcatag
     8161 cctacatagc cggccggagc gccgatcagc ttggccacag cgtgtttttc ctcgtactcg
     8221 ctcatgtcaa agcggagcag actgatcccc agctccttcg caagagttct ggcaatttcc
     8281 gtctttccca cgccggtagg cccgacgaaa aggaagctgg ccaggggttt tccaggatcc
     8341 agaagcccgg ccctggaaaa cttgatggca ttggccacct ccttcaccgc ctcctcctgt
     8401 ccgaacacct gggaggccag gcgtttttcc agcaaggcca gttttctcgt ttcactgctc
     8461 tccaccgtct gtctgggaat ccggcagatt tttgcaagaa tttcgtccac cacatccttt
     8521 cccaccgtct gccgcttttg tgccagagga tgaagctttc tgtacgcccc cgcctcgtcc
     8581 atcagatcaa tggccttatc cggcagaaag cgttcgttga tatatttggc gctcatgtga
     8641 accatgtatt ctatcacacc attctggtaa gacactccgt ggtactcctc atagcgcgtt
     8701 ttaagcccca aaagaatctc tgccgcctca tcctcccccg gctccgctat ctccacattc
     8761 tggaaacggc gggccaggct ccggctcttc tcaaaatacc gtttgtattc ttcgtgggtg
     8821 gtggctccga taaagcggat ttttccagaa gccagataag gctttaaaag attggaggcg
     8881 tcaagacttc cctcccccac cgccccggct cccacaatgt tgtggatctc gtccagatag
     8941 acaatgggct tctcctcctg tgaaagccct gaaagcaccg acttcagcct tttttcaaag
     9001 tctcccctgt actgggtgcc cgccagcatt cctcccagat ccagggcata gattttcgct
     9061 ccctttaaag gctccggaac ctttccctcc gacagcagtc tggcgagacc ataaaccacg
     9121 gctgtctttc ccacgcccgg ttctccgata tgaagaggat tgtttttctc cttccggcag
     9181 aggatctgca tggttctctt cagctccttt tcccgtccaa tcagaggatt tgcctgggaa
     9241 atctcctcgt tcaggcagac tgcaaagcgt ttccagcggc cttttcctct cctgttctca
     9301 ggcccttctg catccgcctc atcctctaag tcctctgcat cctccgcctc atccagcttc
     9361 tctgcttctt cctttcctcc cggccctgtc tcctcagccg aatacagaca ggcggcagac
     9421 ggttcgtccc cgccgtcctt ctcctccgcc tcaatcaagg ccagaagaaa ttctcccttt
     9481 tcaattccct gctctgtcag gtaatagagg gcgaagctct ccttcaggct gaaataggag
     9541 gagaccagat ggcttaaagc cacttctttt ctgccgctgc ttctggccgc ccactcggct
     9601 gtaagcagaa gctcgtttaa atcggcagac gcttccggct ccgccccctc tttccgcttc
     9661 tcctcagaca gaacaggaag cccgttcaca tagtcctcca gctgctctgc cagccttcca
     9721 atctctccct ggcagttctc aaacgcctcc tggaaagccg gctctgccgc tatatggaga
     9781 agcagaagct ccggggtcac gtattccaga tgaagccgct ctgcttcctc caccattccc
     9841 cgaaacgccc gccctgtttc ctcgctgatg tccatctcct gtctctcctc tctttctcct
     9901 caatggttgt ccgccgtgtt ctcccagtac cgaatccggc cctttctcat ccgcctggcc
     9961 gtgtcaggcc tcctctacgg tcaggcggaa gggaaatccc tctgccctgg cctgcctttc
    10021 agcctcctct gccttcgttc tggcaatgtc gtaggagtac gttcccacca ccgccttctg
    10081 attcttgtga acagccatca tcagagccgc agcttcctct tttcccttgt taaaaatagt
    10141 tatcagaatc tccaccacaa attccatggt agtgaaatcg tcgttgtgca tcaccacatg
    10201 gtaaaggctg ggcttcttaa ttctgctttt tgtatgttct ctcgcatttg tctgagccga
    10261 catggcgtct cctcctctca aaacaatcct tctctgaagg tttcagtata ccattgaggg
    10321 ggcggggtgt gcaagagcag agttacctgc agtccgccat ctccatcagc gcctcgatag
    10381 ctgtcagata ggcctctgtc tccacatact cgttgggctg gtgggccagg ttgggctttc
    10441 ccgggccgaa gaggaggatc ttctgctcca gatcatgctc tgccaggatg gaggcgtctg
    10501 tgaagaagtt aattccgatg ctctcctggt tcagccctct ttctcctaaa atttctttca
    10561 gccggcgcac cttctcatgc tcttcctcta tctcaatggc tctccggctg ttttccactg
    10621 taaatgtgca gtcaaacagc ggattttctg tcttcagcct gcctgccgcc tccttcgccc
    10681 gctctaacac catggctgtg tcaagacctg gaaccatacg gatatccatc accgcctcgc
    10741 agccgtctgc cgtcatgttg aaggctccgc cgccgccaat ccagttaatc tgggccgtcg
    10801 actgtcccaa aaacggatga gaaaactgct ctacataggc cttaatttcc tccgctgtct
    10861 taaacagccc gtggatggcg ttggctccct tctccggata agcgccgtgg caggtttttc
    10921 ccttcacaga caggcgcagc cacaggcatc ccttctgggc ggcccccggc ctgagatccg
    10981 tcggctcccc gatcagcata aatctggaag ccgccatctg gctttcctcc acaatccgtc
    11041 tggctcccag acctcccttc tcctcgtcgc aggttcccat aaactgaatg gtatgcttcg
    11101 gctttccggg cagatgagcc agggcgaagg ccatggccgc caggccgctc ttcatgtcgg
    11161 aagctcctct ggcaaagagc ttcccttccc gctcttccac cttccacggc tctgtctccc
    11221 acttatccag gtctccgtaa ggcactgtgt ccagatgccc gttccagatt tctgtctccc
    11281 cgctttcccc tggaatcagg gcaattacat tggcatgggt ttcgtcaatc cgatccaccc
    11341 ggctctcgat tccataggat ttaaaatact gatccagata ctccgctacc gctccctcgt
    11401 cgtcctttcc attgacagaa gggatctcca aaatatcctt taacagtttt accgcatctt
    11461 cagccgctgt cttttccatt tttcccgttt ttttcatttg atctgccttt ctcgtctttt
    11521 gcaactattg taactagcgt cagtgtgcaa gggacaacac gcctttgtac actgacacta
    11581 tatttatgaa acgacaaaga cggcctccgc tcatgccgcg ccgtatttta cctgcgccgg
    11641 cagaaacgtc agccgtctct tctgcttact gctttctttc ctgctgtgca ggttatcttg
    11701 ctttcatgcc ctcaacctgg gcgagagccg ggatggacgg agccgctccc aggcctgaca
    11761 ctgtgatcga tgcagctttg gccgccagat ccatggcctc ccctacagaa agtccccgga
    11821 tcagccctgc cacgaagtaa ccggtaaagg tatctccggc tgcagtggtg tccactgtct
    11881 cagtcctgta aatgggctgc tctgtcaaca ctccatgatc caggcacaca gaaccgttct
    11941 ctcccagagt cagcacgatc atagcctctg gaaacgcctc ggaaagcctt ctgcacagct
    12001 catttccttt tgctgcggcc tccctgcgct ccgcctccgg aagcttcaaa atctggcacg
    12061 cctccacctc gttgagaata aaaatatcta caaaggaaag gggaagctct gtaattttct
    12121 catccatggg agacgggttc agcacaatcc tgagtccctt tttgtgcgcc tgctccataa
    12181 tatagggaag ctcgttgatc tcattctgca gaaccagaaa atctccttct gaaaactggt
    12241 caagcgtctc gtccacctgg gctttctcaa tgctctggtt ggctcctccg tagagaataa
    12301 tacagttgtc gcccttgctg tctctctgga taatcgcatt tccggtgcgg acagaggaaa
    12361 ggcgtctgac gtattcggtg cggacacctg cgtcccttaa aatatccgtc aggaaatctc
    12421 cgtcctgtcc gattgctccc gcatgataaa cctctgcccc tgctcttccc agagctaccg
    12481 actgattgag gccctttccg ccgctgaaga tattcaggct tctggaggag atggtctccc
    12541 ccttctgcac gaaatgatcc aggctgtata catagtcaat atttaatgat ccaaagttta
    12601 atactttcat agtttcaacc accttgccgt ttttttcggg acagactcgg cctgcgctga
    12661 cagcttactc ctctctcatc agccattttg ccagattctg gaagagaacg tcatatccct
    12721 tccactcgca gaactccggc ggcgcccagt gaggagcaca gtctgttgta aacgctgcgg
    12781 agcgtccttt tccatactcg cccagagcga taaacggatc accgcatact tcagctacct
    12841 caaccgcctc aggctttaag acggtcttat tgtatcccag aactctcggc cactccggat
    12901 ccagacctgc taaaaccgga tgctccttaa ccgttacagg acgcacgccc tcgcagtgct
    12961 ccattctgtc gtctgtcgga agcacctgaa ccggaagcac ctcctgaaca gctgtatcct
    13021 gccatttgcc cttgccgtcc acgccggaga aggtcatgta gccgcctacc atgaggagag
    13081 cgccgccgtc cagcacatag tctcttaaca gattgcagcg gttcggcata atctcgcttc
    13141 ttgtgaacgt agcggtggga aggagaagtg tgtttgcgcc gatatcggac aggatgatca
    13201 gatcatactg ctttaactcc tccatggtaa atggaaactc ctccatagcc agatggttgg
    13261 gaaggaaggt aaattcatat ccgcccttct ccatggccgc ctttaaatac ttctctcctg
    13321 tctcgtagac agaggtgtag aaggtgtcga agcccttcac atgtgtggta tagctcatcc
    13381 aggactcgcc tgcaagtaat actttctttg ccatcttttt tattcctcct gtttgtcaaa
    13441 tatgttttta acgttttttt ctatatggtt tttctatata gttttttcta tccggttttc
    13501 ctacgcgttt tttccgccgc tgcagaagtc taaaatcagc tctgcgtaaa taagaatcga
    13561 ctccaggtaa gcgtcaatgc tcacccactc gtcaatgccg tggcactgtg ccaggttgcc
    13621 ggggccgaac tgaatggtag gacagccggc gatgtttctc cacagtctgg aatcgcagcc
    13681 tgccggagat cctaccacct tgactgcctt tcccttagcc gcctggtagg cctttttaaa
    13741 gctgtccaca aacggatgct cctcttccat ctcaaagccg ccgcccgcct ggtaaatcgt
    13801 caccttcggc ggatgagcct ccagccacgg atcggataag gacactctcc ttaccacgtc
    13861 ctcaaactca gccaccacct gatcgtagct catctgaatg ggcagatagt ggacgcaggc
    13921 ggagaaagaa cactctcccg ccacggtgga accggctgtt ccgccggaaa tcacgcctac
    13981 attcaggtta ggagccggaa gaagggggtg cttgtaagtc agaagccatt catgctcctt
    14041 ctcatttaag gcctgcatca ccttgaccgc cttctcaatg gcgctgacgc cgttccgctt
    14101 gccgccggaa tggcaggcct ttccctcgaa ctccaccttg aagaatacga agcccatatg
    14161 ggctaaaatc agctcgtcgc tggttccctc gcacacaacc acgccgtctg ccttctggcc
    14221 gctcataatc gcctgcatgg aaccgtttcc gccgccctcc tcgtcgcaca ccgaggtaat
    14281 caccacatca cccggaagcg tctcaaggcc cgcgtccttc aacagctgca ccgccatgac
    14341 ggaggccatc agcccgcctt tcatgtctgc cgtgccgcgt ccgtacatct ttccgtctct
    14401 gatttccggt ttgaagggat ggctggtcca ttcttctatc tcgtcggcag gcatcacgtc
    14461 gatgtggctg ttgaacatca ggcttctgcc tgcgccgttt cccttaaacg cagcgtacac
    14521 attgtaacgg tctgtctgat tgtgtcccag atttccctcc tggtacagct ccttgcaccg
    14581 tacaatgtcc tcctccttca tgggatccgc cgccgtctca gctcccatct cctcaaacag
    14641 gcggagcatg taatcctgcc cctccttctc caggcctccg gcaatgccgt ggcccagatc
    14701 gtgggtgtca atggaaacca gatttttaag ctgttcaata tatttgtctc tgttttcagc
    14761 cagaacttcc tttaaatctc tcatgcttct ccttaaccgt acattaatcg tacattttaa
    14821 gaacttcctc taccatatcc cagaactttt ccgcgtcaat gtcaatgccc acgtccgcat
    14881 ttggctccag cttctggtat ccgaagaaat cacagttggt tctgccatag gactggacgc
    14941 ttctgatatc aatctctgcg tgcattggct ttgtctcaac cacagacgga tcaatcagcc
    15001 aggcaatagt aatcggatcg tgaagaggac ctccctccca tccgaatacc tccttctgac
    15061 tcttgcagaa gtggcgcatc agatctacaa acagcttcga agccttgttt ccaattttgt
    15121 ccatcctatc cacaatagat ggatagcaga gagcctttct ggttacatcc agaccaatca
    15181 tagtaatggg gcgtcctgat gtaaagcaca cataagcggc atctgcatct gcaataatgt
    15241 taaactcagc agctggggta acgtttccgt ttgtgtaggc gcctcccatg agaacaattc
    15301 tcttaatctt cggcacaatt ctcggctcca tcctgattgc catgccaagg tttgtcatag
    15361 ggcctgtagt taccatggta atgtccccgt cggactccat cagcgtcctg ataataaagg
    15421 aaacggcgtg ctccttctcc agctcctttg tcagcggctc aaatacaggg ccgtcaaggc
    15481 ctgtctcccc gtggatatct ccggctgtca tcttctggcg gatcatgggc tgcccgcacc
    15541 ctgcatatac cgacacgtca agtcccaggc actgcactac gttcagcgcg ttgatctgcg
    15601 ttttttcaag ggtctggttt ccggctacta ctgtcacacc taaaagctcg attttaggac
    15661 tttttccagc cagcataatg gccaccgcgt cgtcatgtcc cggatcacag tccaggataa
    15721 tcttctctcg ttccatgtgt ctgctcctcc tgtttctctg tgaatagatt ttttcctgtt
    15781 ccttttatgc ctgctttccc ataagggaag actctctctt cttagcagct cccatcttaa
    15841 gggccatgga tacagccagc acggctaccg ttacaatata cggcatcatc agtacgaact
    15901 gagccgggaa gccgtaagcc tgaagtctgg ctccgatgga atcagagaag ccaaagagca
    15961 ggcatccgat ggctgtgagc accggattgg cgccgccgaa gtacatcgct gcaactccca
    16021 tgaagcctcg gttattggtc atattctcta cgaactgggt gctgtatcct aaagacaggt
    16081 gagcgcctgc cagacctcca atgagaccgg aaatcagcat tgcctgatac ttcactgcgt
    16141 ttacatgaat tcctgccgtc tgggcagcca tcgggaactg gcctactgcc ctgagtctca
    16201 gcccccatac agtcttatag aacaggaact gcagtaaaat aatgaaaata attacaaacc
    16261 actcggtaaa acaccagtca tttaacagtt ctcctaaaac cggcacattt tccaggaagg
    16321 caaaatgcac acggggaatc gggataatat ccgggtttga gaaagttccg tttgtcttaa
    16381 ataaaacctg cattaaaaac ttggtaatgg caatggccag caggttgata cccataccaa
    16441 tagcgcagat ttcagaattg tacttaatgt ggcccagagc cataatcata gcgataatcg
    16501 ctccgcctac catagctgca atgactccgg caagccagct gcctgtgaaa aagcttactg
    16561 ccacagcggt gaacgctccc accagcataa ttccctctgt accgatattt aaaatattgg
    16621 cctgctgagt gatggccgca caaagggcag cgtaaatgat aggagtcgac gcgcggaacg
    16681 tggcgtaaat taacgacaca ttaaagatct ttccaagatt ttcaaaaagt tccattattt
    16741 atttccccct tccctatcat tgccttttgg ggcttcatcg ttgatgcctg tgcctcctgt
    16801 cttagcagcc atttccttct tctgggcagc cagagccttt ctctttccgt taaactggaa
    16861 cagcagctcc atggttgcca caataatgaa aatagcagaa atggtatcta caatcgattt
    16921 cggaacgccg gtagactgct gcatcgccat agctcctgcc tttaatacag ctaagaagaa
    16981 agccataaat ggtgtaaaaa tcatgttgga ctttacaatc agggccgcta acatgccgtt
    17041 ggttcccaga tcctttgcaa agttgtccag gtagtatcca tgtacgccca gtacctcgat
    17101 acatccggcg attccgccta acataccgga aagcagcatg gcgttaataa ataccttttt
    17161 agagttaatt cctacataat ctgcatggta gggattggtt cccactgtac ggattttata
    17221 gccccacttt gtcttgtaga gcattacaat gaccagaact accacgccgg ccgcgatgaa
    17281 aactcccgcg ttggctgagg atggcttaat aatcttcggc agtgtaacaa gcactggatc
    17341 agactgcggg ttggcagttc ctgcgctcat agggccgctg acaagatagg atccgatgta
    17401 cagagctact gtattcatca gaatagttac gcagacctct gatacattgt aatatgcctt
    17461 taacacagcc gggatcaggg cccaggctgc agccactgcc atagctcctg caaagcaggc
    17521 cagcataaga ataggctttg gaaggaagcc gcagttcacg ccaatccagg ccgcagcaat
    17581 acctcccaga cacacctctc cctctactcc tacgttgaag gcccctgcct tggccgccac
    17641 cgcaaaggcg atggaggtca gaagaagggg cgtaaagcct gcgatggtag ttccaaagcc
    17701 aagctttgtt ccgaaagctc ccttaaatac tgcgccataa gctgccagag gattctctcc
    17761 aattgccaga ataaagatag ctccgatacc cagcgcaagg gcaagggtca gcagaatttt
    17821 ccttaaacct tttaatgact ggctcatgcc tcatctccct ccttcctgat ttcatctgtc
    17881 tgtgcagctg cattctgccc tgctttttct ccgcccatca tcaaaagtcc caggttgttc
    17941 tcattggcct cgctggcctc catctcacct gtgatctttc cttcatggat aacgataatc
    18001 cggtcggaca gagagataat ctcctccagc tccgctgata ccagaagcac gccggctccc
    18061 ttctttttcg cctgctccag ggtgtttctg atggactcga tggctccgat gtcaacgcct
    18121 ctggtaggct gggaagccac cagcagcttt ttattcatgg aaacctctct ggccactaca
    18181 accttctggg cgtttcctcc tgataaggag gatgtgggga gatggtagtc agccggacgg
    18241 atgtcaaact gctctgtcat ctcctgggcg tactgatcct gagccgcccg gttcataaaa
    18301 gcgcccttgg tataaacgcc cttatcaatc tctactgcga tcagattgtc ttcaatactc
    18361 atatcacggt tcagaccgcg cttatttctg tcctctggaa tgtgggccag gccagcttcc
    18421 ctcaccttcc ttggagaacg gttggtgata tccacaccat ttaacagaat ttttcctttt
    18481 tccacacggc gcagtcctgt aatggcctca atcagctcag actgcccgtt tccgtcgatt
    18541 cctgcaattc ctacgatctc tccctcattt acatggagag acatgccgcg gattttagat
    18601 gattccttct ggctgggaac ccatacgtcc tgcacctcca gaatcttctc tccagccttt
    18661 ccgtagctct tatcgatatt taagaagacc tcacggccaa tcattttctt cgtcagatca
    18721 agaggcgtag tctcttcctt gttcacagtt cccatatagg ttccctggcg cataacagaa
    18781 atacggtcgg aaatttccat tacctcgttc agcttgtggg aaataaagac aagggatttg
    18841 ccttcttttt tcaggttaaa caaaatctca aacagctttt ttgtctcctg aggcgtcaga
    18901 accgccgtcg gctcgtccag aataatgata tctgccccgc gcatcagagt cttgatgatc
    18961 tccactcgct gagcctctcc tacagaaatc tggctgacct ttttgtccag ctgaatttcc
    19021 atgttatact ggtcgatata atgtctgact tcttttctgg ctttgtcaaa atcgatggta
    19081 atgccttttt tcggctcgaa gcccagaatc acgttctcca gaactgtcag ctcatttacc
    19141 agcatgaact cctggtgaac cataccgatt cctctggcaa tggcagttcc cggatccagc
    19201 tttgtgatcc tctctccttt tatgataaac tctccgctgt caatgggata cattccatag
    19261 agaagcttca tcatcgtcga ctttccagcg ccgttttctc cgatcagcga gtgtatctcc
    19321 ccctttttca gggtgaattc tccctctctc actgcgtgca cctcgccgaa tgacttcgaa
    19381 atgcccctca tctccactac atactcgctc attgttccct ccgtcctgta cgctcctgtg
    19441 aatttgaagc cctggtctgc cagggcgctt tacccagaga ggggggagcg ccgttcctga
    19501 tgtgaaatcg ctgtgatccc atatcattct gcgacactcc cccctcaccg cctgttttat
    19561 ctgctgtcta ttaagaaact cgcctgaagc ttactgattt gcgccgaatc cctcgtagtt
    19621 ctcaactaca atttcaccgg aaacgatctt ttcctgaagt tcttcacact tatctacaat
    19681 atcttgtggg aacttgtctc caagggcttc cttcataact gagaaatcag ttaagcttac
    19741 gccgccctcg cttaatgtca ggtactgagt gcttccgccc tcaaaggttc cctctactgc
    19801 agactggata accagatagc acgcattgtc tactctcttt accatagaag taagcacgtg
    19861 gccaggctga tccttgtcct gatccagatc tacgccgatt gcatactttc ctgcctcttt
    19921 tgctgcctca aggattccag ggcctgtacc ggaagctacg ttcataacga tatctgcgcc
    19981 ctgctcatac tgagccagtg tcagctcctt gccctttaac gggtctgtcc atgttcctgc
    20041 gaatgcctga aggattgtga tatccggatc gatgtatttc gcaccctgct catatcctac
    20101 atagaaatcg tggagaaccg gaatatccat tccgcctacc cagccgatta cattgtcttc
    20161 gtttacaccc tcaatatctg tcttctgtgt gaacatagct gctgcagcgc ctgccaggaa
    20221 ggaaccctgg ttctgggcaa agctgatgga ttctacgttc ggaagatcta ctgtggtatc
    20281 gataactgcg aacttggtgt ccggatagtt cggcgcatgt tttgaaatat aatctgcaat
    20341 gttggaagaa gcgccgataa ccagatcgta gccgccttca catgcagcta ccaggttagc
    20401 ttcccactct tgagctgtcg ttccttccag ggactttaac tcaatgccga agtcctctac
    20461 tgctttctga gcgccgatgt tacaggaatc attgtaggac ttatctccca gatttcctgt
    20521 gtacacgatg cagactttga gaccgtcttt gctctcttca tttccagctt ccttgctctc
    20581 ttctgccgct ccgccttctg cagccttcgt agtctccttg ccgctgtcgg atgagccgca
    20641 gcctgccagg cttacgcaca tcaatcctgc cattaacaga cacaatgctc gtttcttcat
    20701 gttttctcct cctccataac ctttcgtttc cgtggtgcac ttgcttttta tgatgcggaa
    20761 atttaggaaa ccattttcct acatcatttt ctctgatagt caaatcatac atctatagag
    20821 cgcgtttgtc aatatgtttc gttatttttg tatagatttt cttttgttat ccatcgcttt
    20881 ttaattagat tcactatttt tcaggtttcc cccttcttta tattatgact tttttctaca
    20941 aatacctcag tttccgaaac tgtttttctt actttctctt gtttttgccc ggttcagggg
    21001 gtatactttt atgatacaga gaggagaaag actatgaata ttaaagatat tgcgcgcctg
    21061 gcgggggttt ccgtctctac ggtttccaag gtaatgaacc ggaaagacgg aaccatcagc
    21121 caggaaacaa gagaaaaggt tttaaaaatt gccagagatt acaattacac accctatgct
    21181 tctgttatga cgccttctgg aaaaaccttt ctcatcggcg tactgctgcg ctcctccact
    21241 gtccgaacca ctttaaacgg aattctggag agggccaggg aacttggcta cggagtcctg
    21301 atctcagact ccggctcttc cctggaaggt gaaaaaaagg cgctgtcctc gtttttcaga
    21361 aaccgggtgg atgcggtgct gtgggaggca tttggaacag aaagcctgca gaacatgtct
    21421 gagcttgaaa aggccggaat tcccttcctg tttttcaact gcaccctgcc cggatccata
    21481 aacctggatt atcagggaat gggctatgca gccgcccgcc ttcttattca aaacggacat
    21541 caggatatcg cctgccttct ctcgccggga agccgtacag acgctctgtt tgaaggctat
    21601 aagaagtgtc tgtttgacca ccagctcccc ttccggaaag atctgatatt ccacggaatt
    21661 accccggctc tccttcatcg tctggccagc catggggcta cggctgtcct ctgctcccat
    21721 ttcgcctctg ctctggagct ttatgagaga ggcctgattc tccactgcaa aaccccggag
    21781 gatttctccc ttttatccct cagggacgat gggcggctga aaacgccgtt tccagatatt
    21841 tcctccttct ccattcccca ccgtcagttc gggcgctttc tctgtgagca gttaattcgc
    21901 ctgaccgagc gggaggaagg cgacggatca ggcgttttga ctgaggcgac tgccttttcc
    21961 tgggttcctg aaccagacag cctgtccacc atagggcttc ccttttccat gctgcctaaa
    22021 aaaatggctg tggtgggaag cagcaatgtg gatatttatc tgaaagtaga ccagcttcct
    22081 tcctccggcc gtgtagcgcg cacctccctg tctgcccagc acgcaggcgg aaaggggctg
    22141 aaccaggcgg taggagccgc taaactggga caccgtgttt ccctgattac agcagtgggc
    22201 aatgatacag aagctgacat gctctatgaa acgctttaca aacattccgt agagtcctcc
    22261 ggcatccgga aaaatgactc tctccctaca ggaagagcct acatctttgt ggaacctggc
    22321 ggcgaatcca tgatcaccat cctttccgga gctaacgatg ccctgcgacc tgcggatctg
    22381 aaaaacagcg cccatctgtt taaggacgct gcctacacgt taatcagcac ggaaatcccc
    22441 atggaaacgg tggaggaggc ctgtcggctg accagaagtc agggcggcaa aacgattgta
    22501 aagcctgcca cctgcggtcc cttaaagcct gagctcctga agctgattga tattctcatt
    22561 ccaaatctgg aagaactgaa cgagatctgt cccggaccgg ctgatataaa agaaaaagct
    22621 gcagctcttt taaatcaggg gacagggaca gtcattgtca ccctgggagc tgacggctgc
    22681 ctgctgtgta cctctgggga ggtaaaacat tttcctgctt ctgactttcc tgccatcgac
    22741 aatacaggag ccggagatgc ttttatcagc gccctggcct cctatctgct ctacggcttt
    22801 gatttggagc atgcaattca gattgccggc tatgctgccg gattctgtat tacccgcgag
    22861 ggagttgttc catctctcat tgacaagagt acactggaaa cttatctcca gcagaaggct
    22921 cctgagcttc tgaccattcc tggtcactag gagccctata cgccaattgg cgcagaggta
    22981 actacccttc tgcgccaatc tcttttttta cctgtctcat ctgttttttg taaagaatcc
    23041 agccaattcc agccgccaga atctcagcca ccggaaagga cagccacact cccggcagtc
    23101 ctatgctctt tgaaagcgct aaagccaggg gaggaatcac caccagctgt cggatcagag
    23161 agacaatcag ggagtaaagc ccctgtccca gagcctcgaa gcagccgcag aacaccgttc
    23221 ctgccgccga gaaaataaag cccaggctga tcaggcgcag gcaggaaatt cccatttcaa
    23281 gcatttcccc ttccgctccg aacatcccca taatcgggcc tggaaccgcc aggaacagaa
    23341 ccgttcccgc cgctaaaatc gcgccgcagg agagcatgct gcaggttacc gtttccttca
    23401 ttcttttcag atatccggct ccgtagttgt agctcataat cggacgcatt ccctggataa
    23461 tcccgttctc cggcatgtag acaaagctct gaaatttgta gtacagcccg aagacagcca
    23521 cagccagaga agaaaagctg gttaaaagag cattcagaat gcccaccagc agagacggca
    23581 gggacagcat aatacaggat ggaattccga tggaataaat tttcacagcc acagccttat
    23641 caaactgaaa tcccttaaag ctgatgtgaa tctgcttttc cttcttaata aagagaagca
    23701 ccgccaggcc gcaggccagc atctgcccgg ctaccgtagc tatggcagct cccgccacgc
    23761 ccatggccgg aaatccaaat aagccgaaaa tcataatcgg gtccagaata atgttggtca
    23821 gcgctcccgc cgcctgcaga atcatgggca taatcatatt gccggtggcc tgaaacattt
    23881 tctcaatgta aatgtgaaaa atgcttccaa aggacaggca caccacaatg taggtatagc
    23941 tgcatcccat ggagaaggtc tccggatctg aggtgaaaaa tcccagaaac ggcttcgtca
    24001 gaaacagtcc tatcaggaca aataaaatgc tgtgaagcag ggtaaacaaa attccatggg
    24061 cagccgcccg gttggtctcc tcctgctttc tggctcccag actcttggca atgcaggcgt
    24121 taattcccac tccgtatcct accgccaccg ctaaaatcag attctgaagc gggtaggcca
    24181 gcgatacggc tgtcagcgcc ttctcgctga ttctggctac gaaaatactg tccaccacat
    24241 tgtacataga ctgaatcagc atggaaatca tcggcggaat cgacatggac atcaaaaggg
    24301 gaaagacagg cttcgtcccc atgacgtttt ctcttggttc cataagtgta aatctccctt
    24361 ccgacaaaaa aggaggccat gattccctgt ttaaatcaga aacagaaaaa tctatagcct
    24421 ccggcagtgt ctttttatat gtctttctca taggaacgcg ccctatggtt cagacgcgcc
    24481 ctattaattt atcagattcc cgcctatttg tcaaatcctt tcaggcggat gtaatccttc
    24541 accagctcag ccgtctggtc cagatccaga ttcgtggtgt tgatggtcag gtcgtagttc
    24601 ttcatgttgt gccattcgct gcctgtgaaa tacttgtaat attcccgtct ggacttctcc
    24661 atctttttga tccggcgttt tgccctctcc tcgtcgatgg cgtccacttc cattacgcgc
    24721 tgcactcttc tcaccttgtc tgcgcagaca aagattcgga tcagacgctc cagctcctcc
    24781 tcctgatcca gcacatatcc ggcggctctt cccacaataa tgcaggactc ctctctggcc
    24841 agctcacgaa tcacagagga ctggaaccgg aacagattct ccggcgccgt cacatttccg
    24901 ctcagcaccg gctcctctgt aaaatccagc ttccggccca caatccggtg aagcaggtta
    24961 tttccggcct tttcgtccgc caggcggaaa tactcctccc cgatggcgct cttctctgag
    25021 gtgagcttta aaatttcatc gtcgtaaaaa tggattccca gatcctcagc cagcttccgg
    25081 cccacaatcc ggcctccgct tccatactcc cgttcaatgg tgataatcag atttctattt
    25141 cccataacag aacctccctt ccgccttctt atcctttctc tgtctgcctc tgtgaaatac
    25201 tgtccctcag ccggcggatc tgccgcttct ggtcctgatc cgcccggctg gattccagaa
    25261 tcttctgaag agccctgcgg tacgtatcct tttccagagt gttccatctg gccagatatt
    25321 ccatggtaac cgctggaaac ttcacatagc acacagaaac cgcccaggcc acagccatgc
    25381 tggcgtagta atccggctgc cggatctggt ccagaagacg cagcgtctct gaaatgtgcg
    25441 cctcgtccac ataccagctc agcagcatga ctgccgcaaa ccgggcctca aactcccgct
    25501 ctgaagaaac atacggcttt aaaaaatcga gaacctgcct ttgattcttc ctggtaaacg
    25561 taagtccccc gcaaaaggcg tcgcagacag cccagttgtc aattttatcc acaaatttcc
    25621 tgattcgttc aagcttttcc ccagcttcct cccggactgc gccgatgatc agcccctgaa
    25681 gctgcagctc ctcataggtt tcgtccgtca gccgatccag gcaggcggct ccctcctcct
    25741 tcagaagacg cctggccatt ttccgaagaa gcggaaggcg gactcctaaa atatggtctg
    25801 tccccggaag cagccggctg tgaaactggc ggtagggctc gtcggccagg gcaatcagct
    25861 ctttttgaat ttctgtatat tctttcactt tttacttgat cgcaattaca tcagatcgtt
    25921 tacgcagact gctccgtagg gacggatgct catgcggtaa gcatttccct ttccaagagc
    25981 cgcctcgatg tatgctgtat actcgtccac cagatcattt ggaagcatag ccataattac
    26041 gccggcaaag ccgcctccgt gtacgcggca ggctccccgc tttttctctg cgataaacat
    26101 ctctgtcagg gccagcgcta cgcagattcc ctgctcctgc acatcggctg tcgtgtagca
    26161 gttctgcagc catttccagg aggaatttcc agactcggtg atcttctgga ggaaggttcc
    26221 gaaatcattc tccttcagag cggccacctg ggcctccact ctcttattct cctcaaagaa
    26281 atggaaggct ctcatcacag agcggtctcc cgcataggct ctcaccttcg ccaggttcgc
    26341 aattacgtcc ttttcctcaa tatcagcgca gacttccttt ccaaagaact ccgccacctt
    26401 cttcatctca ttgggaacag aggagtaatc ggcgcttaaa tcggcgtgtc ccttgcctgt
    26461 gttgacgata atcaggctgt gatcctgggc gctgaaatca aagtcaatct tctccactgc
    26521 aggagcttcc ggcttcttga agtcaatggt aatcaggcct cccaccgcgc aggccatctg
    26581 gtctaacaga ccggaggcct tgttccagaa cttgttctct gaatattttc caatgtgggc
    26641 gtaatctacc acgttcattc tgccatcgtt gaaaaatgta tttaacatgg cgcagatcag
    26701 catctcgtag gatgcggagg agctgacgcc tgcggagctg attacgttgc tggtgataaa
    26761 cgcgtcaaag ccgccgatct caaatcccct ctccttaaag ccctggagaa ttcccttggt
    26821 caggtcaatg gttcccgcca tctccctgct gggctttaag tcctttaaat tgataataaa
    26881 tttctggtgg aaggtctcgc ttaaaatgcg cacagtgtct gttccgttct tagccgcagc
    26941 tcctacgcag tctaagttaa tgcttcccgc cagcaccttg ccgtggttgt gatccgtatg
    27001 gtttccgctg atctctgtcc gtcccgggga gctgaataac agcacgtccc cgtctccata
    27061 ttcctttaaa aatccctctg ccacatggcg gtagcgggcc ttattctcct ctgcctgagc
    27121 cgctccgtaa agcgtctcca tcagttttcc tgcttcgtct gtatcgagct tctttaatgt
    27181 ctcttgaatc atcataatct ccggttctcc ttcacccctg gttcttattt cttctgctgc
    27241 ctttctgctg ccagacagca ggttctattc tttttaagta taccatttta acggtagatc
    27301 ctcaatataa tatccccgga aattatgtac gaaaatcgta actggcctga atgccggcct
    27361 gaatttccct gtttccctta aagtccgcta aaatctgtga tagaataaaa aagactgcaa
    27421 aagccctgcc gcggcaggca gaagaaacag cgttaaaata aaaataagga taaaaggata
    27481 gaaatgaacg ataaaagaaa ccagatgcag gaaacctggc caaacggaag aaccggcagg
    27541 cctctgcaga ccagatgggg cgaaaagccc tattattccc tcgattacta tttaaaagag
    27601 acctttggac agaaggttta caaactggcc ttagacggcg gcatgacctg ccccagccgc
    27661 gacggaactc tcggcacagg aggctgcatt ttctgcagcg agggaggttc cggcgatttt
    27721 gccgaatcgc ctcccccctc cggctcaggc ccaggctgcg gaacgcccgc ggcgcctggg
    27781 cgcgtatctc cgtctcttcc tgagatagag caaaggattg cccggcttga cgtctgcggg
    27841 cagattgagc gggccaaggc ccgtgtttcc tcaaaaataa aggatgggaa atacgtcgcc
    27901 tacttccagt cctacaccaa tacctacggg cctctcccct atctgaccgc cctgttttcc
    27961 caggcggttt cccatccgga tatcgcagcg ctctccatcg gaaccagacc cgactgcctg
    28021 ccaaaggaga cgatagctct tttaaagaag ctgaatcagg aaaagccggt ctgggtggag
    28081 ctgggccttc agaccatcca cgaggattcc gcccgcctga ttcgaagagg ctacgagctt
    28141 ccctgctttc tcgacgctct cagacggctg aaggaggcgg gcctgactgt ggtggtccat
    28201 gttattttag ggcttcccgg agaaaccagg gaggatatgc tggaaaccgt ccgttttctg
    28261 gggcgtttag acaatccctt cattgacggg atcaagctcc agcttctcca cgtcttgaag
    28321 ggcacagagc tctgccgcct ttatgaaagg gaaccgtttc atgtcatgga gccggaggaa
    28381 tatttttctc tcatcgccga ctgcatccgc ctgctgcctc cgcacattgt cattcaccgc
    28441 atcagcggag acggcccaaa atctcttctg aaagcgcctc tgtggagcgg caataaacgg
    28501 tttgtattaa actccattgc taaaacgctg cgggagacag gggcgtttca gggcgagtgg
    28561 gcttaatccg cctgccggat cctgcccgcc tcatctaccg taattccgaa ggataatccc
    28621 tccatatagc ggtaaaacgc ctctttttcc gtctcgtcgg ccaccattct cgtataaccg
    28681 ccggaggagg tgcctggcag aaggacgagg gcaggatctc cttccctggg tacttccacc
    28741 tggagaagca tggttttcgg gatgctgctt ccaaagacaa aattgcccag actgtacaca
    28801 ataggctttc ccttataata ttcgattccc tgaagcacat ggggatggct tccgatcacc
    28861 agatccgctc ccgcgtcaat gtactgctgc cccagcgttc tctggtaact ctctggctct
    28921 gtcctgcgct cgattcccca gtggacgtaa acggtcagaa aatcgcagga ttcctttgcc
    28981 ttctggatct cctccaaaag caccgtggaa tcataggccg tcagcattcc agggtgatcc
    29041 gggcctgcgg cccagtaccc ttttggaaat actctggaag ctgccaggaa gccgaaggtt
    29101 ttccctcccg cctctatggt tttaagcgct ttggcctcat ctaaattttc ccccgctccc
    29161 gcgtggagaa tcccggcctc gtccagcacg cggatggtgt cggaaagggc ctcgctgccg
    29221 tagtccagag catgattatt ggccagagcc acaatatccg gccctatctc ctgcatgatc
    29281 gatacctttt cttctggaag gcggaacgta aactgcttgt ccgtctccgg cgttccccgg
    29341 ctgctgaagg gaaattcctg gtttgccata aaaatatccg cctgctctat ggtctggaga
    29401 aatccgctgt ccagaacacc ttcgattcct ccgccccgct cataggcgtt cagcacatgc
    29461 tcagacagat agatatctcc ggcaaacaga agagaaaccg tatctgcctg cctggtcaat
    29521 gtttgctcct ctgcgttttc tttttcccct gtatcttctt tctcttcgtt ttcttcccca
    29581 gtataaatct ggagaaccgg ccgttccgtc tcccgttctg tctgttcttc tgttttctct
    29641 cctgctttct ctgtttccgc cgtttttccc tttatatctt cctctgtttc tgcttcctgt
    29701 ctgaaaggga cttccgtttc catttcccct tctcctccaa tgagccgttt tcccgcatac
    29761 agagcgaaaa aaagaaacag aaggcagacg gcaaggaaca atagccggta cggtcctcct
    29821 gtatggccgg gattcctccg tctgctgcct cttcctcgtt ccatctgttt ctgtttcctt
    29881 tctaaatgtt tcattcactt ccaagtttaa gtcccgctct gtcccagcct caatcctgat
    29941 acgccggatt gcccagccat gataggctgc gcagatgaac gattacaaag taaggataat
    30001 tcctccgtcg ttggcgtaaa cagtagccac tcctgcagta tctgtaataa ccacgtcctt
    30061 aaactgagcc ttgctgcaga tcagatccct gacatactcc gcccgcgccc tgttgttgca
    30121 gtgggcgatc accagccgcc tgtccttcgt ctcccccgcc tgttttaagg caatctctgt
    30181 catcctgcca agggctttat tcatgcctct ggcctgttcc agcttcacaa tcacgccctt
    30241 gtctccggcc ataaccggct taatattgag ggctgtggca aaaaaggcct gaagtcctgt
    30301 gagacggccg ttttttctca gcgtgtccag gttttccagc acaaagtagc ttcccatctg
    30361 atcccggtac tcctccgcct gtcttacgac ctcgtcaaat tccagtccct gttcgcagag
    30421 atctctgata cagagcgcta cgttcagctc tccggcagac gctgatagag aatcaatgac
    30481 tgcaattttc ttggcctctg cgccgtgctc ctcctcataa aggctcttag ccaggcaggc
    30541 agaattgtag catccgctca gatgggcgga caaggtgaca ataaaaatgc actccgcttc
    30601 gcagtcaaac tgttctttaa agtcctcggg agacgggcag gcagttttgg gacaatcctt
    30661 ggcctccttc accagctcca gaaaacgctt ctggtcaaag gtttcgtcgt ctctgatatg
    30721 cgcatgatcc acctgaagcg tcaggggaac catatgaaaa tgaggatcct gcttcagctc
    30781 ctctgtcaaa tccatgcagc tgtctccaag aattttatag gtcataggta ttcctcccag
    30841 gtttgctttt ccttcgatgc ttcgggaatc ctgctccact gttccgaaag tccctccgca
    30901 tcatctggtt ttcattacta tttattataa taatgatgtg ctttaaagtc aagaatggat
    30961 cacagttccc ggatgcgggc cttcagcccc tcctgcctta cgtcgcgatc cagcccaatc
    31021 agcctctggc gtttttccat gcttacagac gctctggtcc atatgacagc ctgaaacatt
    31081 ggatcgtaca ggcagacctc tacctcctgc cccggctgaa gcgccctgcc gccaatggat
    31141 aaccctccat cctctctgcg tgtcagcgtc ccctctgcag tgatcgttcc ctttaaatat
    31201 ccagccagtt tctgaatccg ctccaccgct tccgccagtt cgcacagcac ttctgcccgc
    31261 agataatcct ccggatcctc tcctctgtga aatatcatat tccagagttc ttctccgtat
    31321 gttttctgaa attcctgcag cgctttttgt accggctcca atccgttaag aagttccagc
    31381 tcttccaatt tctcctctcc cttcccggag tttccgaact cggaaactta ttatactcct
    31441 atcttaatga gataatacca ttattgcaag cacttgattt tttgtacgaa acacgcgggg
    31501 actgatgtta tgattgtcta tgataagctg tggaccgcca tgaaagaaaa aggcatatcc
    31561 cagaaccatt tatataaata ttataatgtc agccgcgctc agatataccg gctgaagcac
    31621 aatgaggtcg tgtacaccag cacgctgaat atgctgtgca atattctggg atgcgacgat
    31681 atctcggata tcgccacctt cgtgccggat catcctggag acgagggata ccgggagccg
    31741 gcggcgggag aaaaatagaa ttgttgtgtt ataataaaga ggaagaggaa agtttttacg
    31801 ctccgcttaa agtcgctgaa aactttcctc ttcctctttt ttgtcggctt atcggctggt
    31861 ttttgcgctt cgcttaaagt cgctgaaact ttcctcttcc tctttttact ttactgtttt
    31921 ttcttattct gccagttctg tcatgatctg gttgcttctg gcgatgaatt tcgtcattct
    31981 ctccgggctt aaggttccgt ggcttaacag agccaggtcg taaagctgct cgcagattac
    32041 aggagtcttc tcgccgtctg tgtgctctaa cacgtatttt accaggctgt tgttagcgtt
    32101 taatacaagc acctctcctg tgccgccgaa catggacgga tccatgccgt acatattgta
    32161 catcttcatc atttcctgca tacggcgcgt ttcctcggct actgtgatca tggaggatac
    32221 ggactcattc ttcagcttct caacctttac ctccagctta tcgtttccaa gggccttacg
    32281 gaaggtttcg gtcagggtct tagcctggtt ctccagagtt tccttgtctt cctccttcac
    32341 ttcttccttg aagatctcgt tgacgtccgc gtcgattctc aggaacttca cgttctcgtg
    32401 cttctgctcc tcgtgggtga taaacggatt gtcaatgttg tgagtcagaa tcactgcgtt
    32461 taacttttcc tcgcggaaca tgttgatgta ctggctctgc tccttctcgt ccgtcacgta
    32521 gaagaccttg ttctcgtgct tgtccttagc cgcctccaga taatccttca aagtcagata
    32581 tttgccgtcc agatccttga aaataatata ctcgtccatc ttctcggcaa acttctcgtc
    32641 tctcaggcat ccgaacttaa tgaatgggct gatatcgtcc cagtatttct cgtagttctc
    32701 tctgtctgtc ttgcacatgc cggacagctt atccgctacc ttctttgtaa tgtaatcgga
    32761 aatcttcttc acaaagccgt cgttctgaag agcgcttctg gatacgttta aaggcagatc
    32821 cgggcagtcg ataactccct ttaagagcat caggaactcc ggaatcactt ctttaatatt
    32881 gtcggcaata aatacctgat tattgtaaag cttgatggtt ccctcaatgc tctcgtactc
    32941 catgttgatc ttcgggaagt acaggatgcc ctttaagtta aacggataat ccatatttaa
    33001 gtggatccag aataacggct ccttaaagtc cataaatact ttgcggtaga aggccttgta
    33061 ctcctcctcc gtacactcgt tggggtgctt gttccacaga gggttcacat cgcttaaaga
    33121 aaccgggcgt tttaaaattt tgtatttctc cttggccggg gaaacctcca ccgtctcctt
    33181 ggttccgtcc tcattctctt tttcctctgt tttagcttct tccacaattg tttcaacaat
    33241 cgtatctttt tcgtttaatt catctttttc gatagtctca tattccggct ctgcctttgc
    33301 attattcagg aaaatcggaa ccggcataaa ggaacagtat ttttcaatga cctctctggc
    33361 tctgtactcg ttggcaaact ctgtgctgtc ctcgtttaag tagagcgtaa tctttgttcc
    33421 taccgtctct ttgtctccgt ccttcatgtc gaactctgtg ccgccctctg attcccagtg
    33481 aactggcttt gcgtccgctc tgtaggaaag ggagtcgatg gttactttgt cagctaccat
    33541 gaaggcagag tagaagccca gtccgaaatg gccgataatc tggtcttcat tggccttatc
    33601 cttatactta ttcaggaaat cctgggcgcc ggagaaggcg atctggttaa tatactcgtc
    33661 catctcctcc tcagtcatac ccataccgtt atcctcgatg ataatggtct tatcctccga
    33721 gttgaccgtc acctgaatct ggaactccag atcctccggc ttctcccact cgcccatcat
    33781 ttccagcttc tttaacttcg tgatggcgtc gcagccgttg gaaatcagct ctctgtaaaa
    33841 aatatcgtga tcagaataga gccatttctt aataatcggg aaaatattct cgctgttaat
    33901 ggataaactt cctgtctttg ccatgtgtca acactccttt ttgtattctg tatttcagcg
    33961 gcctcttgtc tgtttcagtc tggcctttgt tctcaattcc ttctctattt tagtccgcct
    34021 tcttccagat gtcaatagaa aatcagcact cgttttaatt gagtgctaat aattcatcag
    34081 ttcctttcct cttttttgtg gaaattctta caattttttt cattttttct cttccattga
    34141 cttttcaatc ctgtgttttt ataatgaatt tgtttcacat gaatggaaaa agcaggaggc
    34201 ttacacaaca tgaaatataa gacaaaaaca ctcaaatacg ggcttgccgg aattctctct
    34261 ctggctatgg ccgccgcccc ggcgggaacc tgcctgccgg gatttctgcc tgcccaggct
    34321 ctgactgttt atgcaggacc agcagaggag gctaccgttt cttcagacga gcccacaggg
    34381 ccagctgctc tggggcagac acaggggctg agcgcctcca actattacaa tgtgcgttta
    34441 agcgatccca ttgtaaagcc tgtggataaa tattcctatg agcagatgga tcgggatatt
    34501 caggccttaa aaaaccgtta tcccaaccag atgaccgtca atgtcatcgg ccagtcggcc
    34561 gacggacgga atctctatga cattatcatc ggaaacccgt ccgcctctga gcatatttta
    34621 ttccagggcg ccatccacgc cagagaatac atcaatgtac ctctcatgat gcagcagctg
    34681 gaatatctgc tggcctgcca gaatacggga accttcgagg gaaaaagtct ttcggaaatg
    34741 cttgggcaga cagccgttca ctttgtgccc ctggtaaatc cggacggcat ttccatcagc
    34801 cagagcggcg atggcgccat ccgttctcca gagctgaaag cccagatcag agcctgctat
    34861 gaactggata ctgccgaggg acgcaccacc gctgactatg atacctattt aaggcgttgg
    34921 aagagcaacg gacgcggcgt ggatttgaac cataactttg acgctggatg gaatacctta
    34981 aatacagtgg gacatccgtc ctccaccgac tacaagggaa cctcccctct ctccgagccg
    35041 gagtcccagg ccctggccgc tctgaccgac cagtacccct tcgccgtctg cattaactat
    35101 cacgctatgg gacaggtaat ttactgggat acggagaata accggcagac ctcttcctca
    35161 aaagagctgg cagagcttgt ctccaggcat aacggctacc agattctggg cagcaagggc
    35221 gtaggaggct acaaggactg gctccagcag agagaaaaat ccatcccggg cattaccatc
    35281 gaggtgggca aatcggcctg tcctgtcaat ttctcggagt acgaaactat ccgggagcag
    35341 aacgaggccg ttccaggact gattatccag tatgtgatct cgcattagag ttcagcattt
    35401 tagacagcaa aaagagagga tgcattttgc agcggcttcc atgggagcgc gcaaaatgtt
    35461 tcctctcttc tgtgttttct ctgccttata tggctggaaa gaaccggctg attttccttt
    35521 atttttcctc aaatggaata ttctttttct tcagaaattc cttcacagct ccgtcccact
    35581 cgtgctccag agtcttgtcc agagtaaagc ggctgacgga ggttcccgtg acgcaggaaa
    35641 ggcgtttatc ctcataacgg atattcagat acaggccgtt tacctctgat gaggcaaaac
    35701 ctgtctgtct gtcccttaga aaggcctcct gggcctttcc ggaaagctgc agaacaatgt
    35761 gaaagctttc cggcagacgt tttcccttaa tcagtgaaaa acagaaaggg cgcagcgcga
    35821 gccaggctga aaatccctcg attccctgct cctccctctc ctccgccgaa tagtaatcag
    35881 ggcgtatccg cccgtctatc tgaaagctgt taaatgtcac gatctgcgct tccctgagca
    35941 gaaaatggtc aaaggtggtc cctataaaca gctgtcttgt aaattctttt atttcttcta
    36001 tttgaagcga taccatattt ttcctccaat atctgctttc cagatttctg gctcctattt
    36061 accatatcag caggaaaaca agcggctgcg aagcagacat ttgttttcac ctgatatggt
    36121 aacgacaaaa tgtcttagct gccagaggca gcggcagatg tgcaaagcac agctgcattt
    36181 tggagttatt ataccacatt cactaagctc gaaaaaacct cgctaagtgt ctgggtatga
    36241 ctcgcactaa cctcttgctt cgcctgcggc ttgcattcgc taagtgctcc tattatacca
    36301 caccttcctt ctctcttcca cacactaaca gttgcaaaaa agcgatgttt tatttatact
    36361 tctatgtata actacagaaa ttaggaggac tttcacacaa tggaacagta taaaaatgat
    36421 ttaaacgggc tgacagagct tcttacggca ggcgtgtctc cccttcacac cattcggcat
    36481 tctatgaatt tactggaaag ccgcggcttt acagagcttt ccttagataa ggcctgggcc
    36541 ttagagcctg gaaagggcta ctttgtcaat gccttcgaca ctactctcat cggtttcacc
    36601 gtgggagagg acgcggcgga gcacccaagc ttccgcatcg cctcctccca tacagactgg
    36661 ccctgcctga tggtaaagcc gtctccggaa atctctgccg aggggtacgc aaagctgaat
    36721 gtggcagtct acggaggtcc gattttaagc acctggcttg accgccctct ctccttagca
    36781 ggaaaggtat gcacagtttc tgaggagcca ttccatcccc aggttcatct ggtagacttt
    36841 aagagaccgc ttttaacggt tcccaacctg gcaatccact ttaaccggga ggtaaataac
    36901 ggcgtggcct taaatcctca gatcgacatg cagccgattc tggctatgct ggacgagacg
    36961 ctcaataagg acagcttttt cctggatctg gtggctgaag agctccatgt gaataaggaa
    37021 gatattctgg attaccagtt ctatatctac aactgcgata tgcctcagac tctcggtatt
    37081 cacaatgaat tcctgtctgc gccgcgcctg gacaacctga ccagcgtcca cgcctgctta
    37141 agcggcctga tggaaagcag cagaaagcgc ggtatctgcg tagctgctct ctacgacaac
    37201 gaggaaatcg gaagcagcac caagcagggc gcggcctctc ctctgacaga cagaattctg
    37261 gagaaaattt atttaagcct tggatacagc agaagcgatt tcctggacgc tctgttcggc
    37321 ggcttcctcc tctctctgga tgtggcccac gcttaccatc caaacaaggg tgagaaatac
    37381 gatccaaagg accgcgttct gttaaatgac ggcgtggcct taaagctggc cgtaaaccag
    37441 gcatacgcta cggatgcttc ccatgtgagc gtcattgagg gcatctgccg cgctcatgaa
    37501 attccttata agaaattctc caaccgttcc gacgtcaagg gaggatccac tctgggaagt
    37561 atttcctcct gccttctgac catgcctgca gtggacgcag gagtcgctct tctggctatg
    37621 cactcctcca gagaaatgat gggcattaaa gatcagtggg ctctggcaga gctgacccgc
    37681 cagttcctgg cttaaaaaga aagaaaaatg gggaagaaag atttctcgtt ccacttaaag
    37741 tcaccgaaat ctttcttccc catgaaagcc aaaaatgtag tttaaaacgg cgaagaaacc
    37801 gttctcattc cgcttaaaat cacagaaatt tttcttcccc atgaaagcca aaaaaaattc
    37861 attttaaaac aacccggctt ttaccgggct gtttctcttt ccatattctt ctctgccttc
    37921 agagccagta tccgcatcgc cgactcttct atccgggact cggtcagcgc ccctttttct
    37981 accgcgtctt tcacagcctg tacggccgcg tcaaaatcct ccggcatgag tatcatgtcc
    38041 gcgcctgccg aaagagcggc cacagcagcc tccccgctgt catagctttc tgtcacagcc
    38101 cccatattca tagcgtctgt aatgataatt ccctcaaatc ccagctgctt tctcagcacg
    38161 tctgtcagca gtgttttgga aaagacagcc ggacggccgt cctcttcaat ctccgggacg
    38221 ccgatatggc ctgccatgac gaaatcggct ccgctctcga tccctgcggc aaatggcaga
    38281 aactctgtct ctgaaagctc ctccagagtt ctgtgaagca caggcttcgt ctcatggctg
    38341 tcctccgccg ttcctccgtg gcctgggaaa tgctttaaaa cagggctgac tccgtgcttt
    38401 ttcagtccct tcacttcctc ggaaaccatg cgcgacacta tctctgcatc gcttccgaag
    38461 gaccgtctgg ctactaccgt attgtcctga ttcgtgagca cgtccgctac cggcgcaaaa
    38521 tctacgtcaa agcctaaatc cgccagatat tttcctatgg tctctcccac ctcaaaggcc
    38581 ttcgcctcgt cattggaagc tcctatttta ctcatatcag gaaaggcttc cagggaaaat
    38641 ccctcttttc cgctgattcg ggctacctgg cctccctcct cgtccacagc cagaaaaggc
    38701 ggcagaccgc ttctctcttc tccgtaccgg gccgtctttg cgagcatctc cctggtctgg
    38761 tccttatcct ttaaattctg gctgaagtag acgattcctc cgaccggacg ctcccagatc
    38821 gcgtcctttg tagcttcccc ggccatgtaa acctcatcgt agccagtcag cgcctccggc
    38881 gtcaccataa acagctgaaa aatcttttcc tccagagtca tggaagagag aagttctgca
    38941 gccatttttt ccgcctctga atcccccttc tccatggctt ctttctgggt ttccttctgt
    39001 tcctctttca aagtttcttt ctgcgcttcc tcctggctgc ctttctggtc agactcccca
    39061 ttttcccggc tgttctctgc agcttcggct tcctccggct ttcctcccag accgatgcca
    39121 gtgtcgtctc ccggaagcag ctccgggcgt attgatccgg cttcctcccg gacagacttt
    39181 ctgcctcctg ccaccgctcc tgccgccgcc agcagaatgg ccgccaggac ggccagaacc
    39241 aggagcagaa cgcgccgcct cttttcttcc tggcgcctcc gcctgctcct cgccctggaa
    39301 cgccttctcc tctgtcttat ctgttcctca tccattccta ctctcccagc tgctctgtct
    39361 gaatcaacgt atgctttctg taaatttcaa aaaagtcggc gttttctgca tgggcttccc
    39421 cgccaagagt cagagcttcc cagtccttca cagaatcgtt cagggtaatc ccctccttga
    39481 atccgctgta aatatcctga aaggccttct gccttctggc gtcgtaaatc tgctccttcc
    39541 gctgggctgt ggcctcctgg tcgtagtcgt tgtcgcatcg gatcacacag tattcaccct
    39601 ggtcctccac aactttgctg acctcccctg tctccagggc aaaagcggcg taatcgtaat
    39661 cctcgcccct gtctgcccgt ccaatctttg cggaggatac ctcaagacct tctgacgcgg
    39721 ccgccttttc cagagaagct cccgcctcta tgctgtctga cacagcctgg gcggcctccc
    39781 gatccgctgt cctcacctct gagatctgga tcaccttggc ctcgctgtcg ctgacctcca
    39841 tatccagatc cttcgtcagc tcctccaccg ttttattggc caggcagtag tcgtgaaaca
    39901 tggtattgac cgacgtctcg tccactccca tataggaaat atcctctggc gtcagagcgg
    39961 ccagatactc ctcagacgcc ttggccatgg cagaggcctc ctcctctgtc agggaaatat
    40021 ttctctcttt ggccaagagc gttaatattt tcagttcatc cataaagctt ttcagctgtt
    40081 cctttgtgta ttcctcaaag gtttttccag actcgtccac ctgggcagac caaatctggc
    40141 cggtgcacag ctcctcgcag gtgtttttct gagacatggc cgctatcata atttccggcc
    40201 gttcatagcc cttctcgcct cccatccccg ccagtataga ctctgttttc tgacatcctg
    40261 acaggagcag aggcagagaa atcagaaccg ccgctgcaga cctgattctc catttttttc
    40321 ttctgctcat ccttttctcc tttgccggca gagcgactgc caggctacag cagcgttttt
    40381 aaaattttta aaacgccgtc tctcacattg gtgtctgcct gaaagcgggc ggcctgcttt
    40441 acctctggtc tggcgttgcc caccgcgaag ctgtaatagg ccctgtttaa catttccaca
    40501 tcgttcagct gatctccaaa ggccatcgtc tcctccgggg caattccaag gctctcctga
    40561 agagttttca cagcctctcc tttgttaacc tccaaagcca tgcagtccat ccacatgtcc
    40621 ccggaaatcg taatcttcat cctgtccttg tacttatccc agaacgctcc tgcctctgcc
    40681 tgaatatcag attttttgta ggccgccacc ttgatgatgg aatcgtccac cttagtcaca
    40741 tcctccacct ggactacgtc gaaatggtat ccgtctctca cccagttgat aaattcctga
    40801 ttttttgtct ccatataagc gtggctggat ccgctgataa ccagatccag gctgggattc
    40861 tttctgatat cctcaatcag ctccaccgca tccgctcttt tcatgggata gagaaacaga
    40921 tttctgccaa ggcatcccag ataggcgccg ttttccgcaa tatagaaaat ttcctttccg
    40981 atgggggcaa aggtgtattc aatgctggcc gcctgacgtc cgctggccgc tgcaaaatga
    41041 atctgctttt ccctcttcag gcgcataatc acatcaaaca gctcttgatt gatcttgttt
    41101 tctccatctc tcaccaaggt tccgtctatg tcagatacta tcagcttaat cattcgattc
    41161 cctccgccag ttctctcagt tttcgatagg ttctgcctgc tggaagtccc accacgcttg
    41221 tgtaggagcc gtttaccccc tcaataaaag cggcgaacac gccctgaacg ccgtaggccc
    41281 cggccttatc catggactcc ccgcaggaaa tgtactcttc tatctccctt tctgtcatgg
    41341 gagctacaga cacgtccgtc ttctccgcaa aggtaacggt tctgccctca tacagaatgg
    41401 taacgcctgt gtaaacctgg tgcacacggc cggaaatcag ccggatcatc cgtttcgcgt
    41461 cctcctcgtc tttgggtttt ccaagaatct ccccgtcggc cgccacaatc gtatccgcac
    41521 cgatgactgc aaaacgtcct ccaagctctt tctggcagcg tctatataca tcctccgcct
    41581 tctgccagga cagctccttg acgatctgct ccggatcaga ggaggtaatg tgttcctcca
    41641 cctgggaggg cataatcacc ggctcaattc ctatctgatt taaaatatcc ctccttctcg
    41701 gagaggcgga ggccagcacc accggaaagg aaaaaacctt ccagatctgc gatccgcatt
    41761 tattctgttc tttcatatat aaaatctcct gttttctttg ctgtcctctc ttttatacca
    41821 taaaaacgaa ggtctggcaa acttccgttt tccttttatt atgcagaggg catttctccc
    41881 gacgggaaga aatcaaaaag gctcatctgt ctggctctgg cttcaggcgt tcccgccagc
    41941 tcctcgttct ggatttctgc ctccggaagc tcttccagaa acggcgacgg ctctcctgag
    42001 gtcacgagaa tcagctcttc tctggctctg gtcatgccca catagaaaag gcggcgttct
    42061 tcctccgcct gctccgtctc cagaggaagc gatccttttc tcatgcccgg gataataacg
    42121 gctggaaatt ccaggccttt agaggcgtga agcgtcatca gggaaacggc gtccgctgcg
    42181 tagcgtttct ttccgcagcg ttttaagtcc ccctcccttc cccagaagag agtaaacaaa
    42241 aagtctttca ttgtcttatg aaacatggcc atcgacgcaa gccgggccag gggctcgtct
    42301 tccttcagat cccggtcgcc catccaggct ttcagaagat ccgcaggctt tttcccggcc
    42361 ataggccggt atttttccag cagctgcaaa agcttctctc cgcctatgcg gcggttcaga
    42421 aattggacgg ttctcttaaa tgccgtttcc tccattccct ccccagcctc tgtcagaaga
    42481 gcgaaaaatc cttccgcctc acggacggta tctgcctcca gaaacgtccc tcttcccgtg
    42541 acaatatagg ggattccctc tgtcctcaaa cattcctcca tctcttctgc ctggcggttt
    42601 gtcctgcaca gcacggcaat gtctgaaaag cttctgggac ctttttccaa aaaagtgccc
    42661 cgctcctgag cgtccagcat gtcgatgccg cctatcatcc ggttaatttc cctggctgtg
    42721 aaaatcccct cagagcgcct tccccctgcc ttcaccacgc ggactggatc cccggaaccg
    42781 gcctttgcgg caagtgttct ctccccgcct ggattgtggg aaatcacgct gcaggcagcc
    42841 tttacaatcg gttctgtgga gcggtaattc tcctgaaggg cgataacctt tgtctccgga
    42901 atgtcctgca gaagcctctt aaagcactct gcgtcagagc ctctgaagcc gtaaatcgcc
    42961 tgatccggat ctccgataac aaacagctct cttccctctt tgttccactc ccggatcagc
    43021 gcgtactgga gagggctgat atcctgaaac tcgtctacca gaagataccg aaaatgggag
    43081 cagaagcggc agatggccgg gcagttctcc ctgagcagcg aaaccgttct gatcagcaga
    43141 tcgtcaaaat ccagccagcc ctgcgcttcc atggctgttc tgtatctgtc aaaagctttc
    43201 tggaaggaat tctcctcctt ttctcccgtt ttttctgaca tctcctgagc cagggccagt
    43261 tccgtctttt ttctggaaac acggcgcaga aattctgtgg ggcgaagggg ttttgactcc
    43321 tcctcaagaa tctcttccgc cagggcagaa agctccagcg gatctgccaa atctgccttt
    43381 tcacctgccg cttccagcat tttcaggcag atagagtgaa aggttcctgt ctgaatcagg
    43441 ctctggcccc tcttatttgc cagctcccgt ttcagacgct ccctgagttc tcctgccgcc
    43501 tggttcgtaa aggtcaccgc cgtaatctcc gacggcttga ctctcctttt ttcaatcagg
    43561 catttgattc tggctgtcag cgttcccgtc tttcctgttc caggtccggc tatcaccgcc
    43621 agacaggagg agggaagctc tgccgcctct ctctgctttt cattcaggag ggacagaaaa
    43681 tctgccggcc tgtcagccct tttatccggc tccccggcca aagcctttgc tgaaaagttc
    43741 tcttctccag actgttcccg ctcatgtttc tcgcagccag acgccgttct gtttcctgcc
    43801 tctgaatccg tcttcgtctc gaacaggccg ctcatgctca tctgtccctc cgggctctca
    43861 atctcgtccg gagtaaacag ccgcacagcg ccgtactccc cgtcaaagcc tggcagacgc
    43921 tccacctttc cctcccgcag cctcctgatt ccctcggcgg tcagataacc gcattcccgc
    43981 ttaatgtcct cgatgggaac ctcccgcaga atggcaaact ctgttcccag cttccggatc
    44041 atggtctcat actcttccct gaccttcttt ccggcggcgg aacggcctgt ggaggccgcg
    44101 attacctcca aaagcggaac caggctctca aaaggcttcg ccttctcagg tacaaagcct
    44161 tccggccggt cggccagctg ggcaatccgg tgggaaactc ccatggtcag gcgtttctgg
    44221 cagacagggc agattcctcc ctgggcctct gcctctgcag gactcaggca gatatggcat
    44281 ttcctgtggc cgtcaaagtg gtactttccc tcctccggga aaaattctat ggttccgtca
    44341 agcccctctc ccgtttccac cgcctgtttt aagccataat aagacaaatc tccgcttaaa
    44401 aggttggctt cccgcccaag cttggccgga gagtgggcgt ctgaattgga aatcagctgg
    44461 aagcgatcca atgcggaaag ctgccagttc ataggcggat cggaggagag ccccgtctcg
    44521 acggcatgga tatagggcgt cagctcccca aagcactcct ccgcccggtc aaagccagaa
    44581 agagcgccga acatggaaaa atgcggcgtc cagatgtggg cgggaataaa catgccctcc
    44641 gggcaggtct ccagcataat ctccagcaga tcatggcagg acaggcccag aatcggcctc
    44701 ccgtctgaat ggatatttcc aatggcctcc agcctggccg acagcttctc cgcctcttca
    44761 aggcccggca gaagaatcag gctgtgaacc tttctcactt ttccatcctg tttgtagata
    44821 gagctgatct caccggaaac cacaaatctg gtccgttcct cctccgctcc ggcctccggg
    44881 ctcagaacgc agtcctcccg gagacggtac agaccgtcct ctgccggtat cagcttttcc
    44941 ttcagctcct ctctccaagc cggatgagta aaatctccgg ttcccagaag ccggattccc
    45001 ttctttctgg cctggaaatc cagctgctcc ggcgtcaaat cgcggctggt agccctggaa
    45061 tacctggaat gaatgtgcag atctgcaata tacataaaat ccctccctga gcgcttgtct
    45121 gttttctttt ctcttttttc tctactgtct ttttctgtga tccgcttctg cttatacgcc
    45181 ccacagtgct tttaccgctt cagaaagccc ctggtcggaa aagatttcct cttcccagaa
    45241 agcgttctga agaaactcca gattctcctc cgaatactca atttcctttg aaagaagacg
    45301 gatatgctct gcctgcgcct ctctggaaag acctccctgg cggagaactg cgtttaagtc
    45361 tgtcagcctt gcgagaactg caaataaaac agccagaccg gcccgggagt acgcgtcccc
    45421 gtcaaaagcg cattttccaa aatagcggta aactccatac tccaccagcc gttcatagag
    45481 ttctgtcccg tcctcctgtc tggccgcagc cagagacagc agctcctcca cagaacagtc
    45541 aagctcatcc agaagcttag tccagaactc ccccataggc tccagctgcc tcaaaacggc
    45601 gaacagctgt ctgaaatacg ctgctctctc ttcctggagt tctgggtttt ttactgattt
    45661 ttcagaatat tcagcatttt cggcgttgaa acgctctgaa ctctgctctg aaagccgacg
    45721 gattttaccg gctgtctctt ccagctcttc cgtgtcgtcc agacattcct gaatctgtcc
    45781 agccagctta aggaactgga cgattcgatc cgccaggccg ctcctggaag ggctgctgtc
    45841 ctcctcattt tcctgtaaag cgccgcctcc ctccaaaatc tgaaacgccg cttccctggc
    45901 agaaaggata gataaaaggt aggcggcttc ctctgtccgg ggctgtttta cggctttttc
    45961 ccactgcctc ctctcctctt cgctttccca ttccacagta agcctgagag ggccggattc
    46021 cgacacaaac agtctcgcag cctcctcgca gcacaggcca agtcccgtct ccgtccagtc
    46081 taaaagccct ggaatttcct cataccactc ataaaatcta ggatgctccc tgcagatgcc
    46141 gcacaggtgt tcctccccca gatgaataaa aatatcgcac aaattgctgt cgtttaaaaa
    46201 agcacagcgc tcctgctccc cttttaaacg gaaatgaggc gttccttccc tggaaatccc
    46261 atcttccagt ctctttccga actctccttt taccgttctg taaaactgat ccgtctcctc
    46321 atctatgtca atttcccatc cgatgcagca gttatccctg cacctggacg cgatacactg
    46381 aaagctgccg cagtaagaag gttttactat cattgtctct ctttctcctc tgtctgattc
    46441 tgtaaaatat tgcaggctat ctgtatccag gcgcagacag cgcctgcttt tcatatacca
    46501 gactcagtat accactgggc gcagcgcccg gcaacttgca gcgctgcctt aaaatgattg
    46561 taagccttct ttctatatgg taagataaaa tatgataaga caaatgaaca ctggttttga
    46621 cgaaaggaga agcaatggaa cacttagaag gaaaccgtct gccgttaatc ggcgatacag
    46681 cccctgcctt tcaggcgctt accacaaaag gaaccgttca ctttccagac gattatcagg
    46741 gaaaatgggt cctctttttc tcacatccct ctgatttcac ccctgtatgc accacagaat
    46801 ttatgaccat cgcctccatg gcagaagaat ttaaagcact taacacagag ctgctaggac
    46861 tttccgtaga ctctctgtac tctcacatcg catggatccg ccggattgaa gagctgtcct
    46921 ggaacggcat tgagcaggtt catgttgatt tccctgtcat tgctgactta aacatgaagg
    46981 tatcccatct gtatggtatg ctgcagccca acgtgtccag cacccaggct gtccgggccg
    47041 tgtttatcat tgatccaaac gctgtcatcc gggcaattat ctattatccg ttaaatctgg
    47101 gacggaattt tgacgagctg aaacgcatta tttcagcgct tcagaaggcg gacgccgatc
    47161 actgctccac tcccgccaac tggcggccgg gagacgatgt gatcctccca tcccccgtta
    47221 cctgcgacga agcaaaggag cgggcagaac atcccggaga aaacgaatac tctctcgact
    47281 ggtttttaaa cttccgaaaa gaaaagtagg acaacatttt gtcagaaaat cgaccgttta
    47341 tcttcagata ttcgtaaatt gcctttttcc tcctgctccc ttataatggt gacaggaaca
    47401 ccagctggtg attaaaagga ggatcattta ttatgataaa aaaacagttg attgcatgtt
    47461 ttatggcagc ttctctggct gctgcatccc tgacgggatg ttccggcagc ccttcttcca
    47521 atgagacatc tgctcaggaa actgttgcca atgtatcttt agacgatatt ttaaaggata
    47581 tcaaggaagc ttacggagaa aattatgttc ctgattcttc cgtcgacgag cagatgcttt
    47641 ccgatattat cggactttct ccagatctct atgaaagcta tgtggcagag atgcctatga
    47701 tcagcacctt tgtagaaacc tttatcggcg taaaggcaaa ggaaggaaaa ggcgaagagg
    47761 cagaaaaagc cctgaatgct taccgcgatc agctggtaaa cgataccatg cagtatccca
    47821 tgaatgtggc taaaatccag gcttcccagg taatccgcca tggcgactat gtattcttcg
    47881 ttatgcttgg cgcgccttcc gacgaggcca tggaggaagg tgatgaggaa gctttaaaat
    47941 ctgctgctga aaataatcag atcgctgtcg atattattga cggatacttt aaataagcca
    48001 tggtatttag cagtctttta tttctgttcc gttttcttcc cctgtttttg gcgctgtatt
    48061 tcgcagcgcc aaaacggttt cggaacagta ttttatttct tggaagcctt attttttacg
    48121 gctgggggga accggtctat atctccctcc tgcttttttc tactctggtg gattttgtcc
    48181 acggaaagct ggcaggcagc ttccgtgaaa agggaaatat gacagcagcc aaatgggtag
    48241 tggcctcttc tgccgctatc aatttaggac tgctgattat ttttaaatat acggatttct
    48301 ttatccgctc tttcaatgaa ctgaccggca gcagcattcc ccttctggga ctggccctgc
    48361 ctatcggtat ttccttttac accttccaga ccatgtccta taccattgac gtctaccgcg
    48421 ggcaggctcc tgttcagaat aacctgatct ccttcggcgc ctatgtatcc atgttccccc
    48481 agttgattgc cggtcccatt gtccgctatc aggatattgc gcgggaatta aacagccgcc
    48541 gagaaaccgt ggcacagttt gccttcggtg tccgcctttt tatcatagga ctgggaaaaa
    48601 aggtgctgct ggctaaccag gccggcgctt tatggacgga aattaccgcg attctccctg
    48661 gagatcgaag tattttaatg gtgtggatgg gaattctggc cttttccttc cagatttatt
    48721 ttgatttttc cggatactct gacatggcat ccggactggg ccatatgctg ggtttttatt
    48781 tcccggacaa cttccgctat ccctacattt caaaaagtat tacagaattc tggagaaggt
    48841 ggcatatttc cctgggaacc tggtttaaag agtatgtcta cattcccctg ggaggcaatc
    48901 gaaaaggagg tctgttccag atacggaata ttctcattgt atggcttctt acgggaatct
    48961 ggcacggcgc agcattaaat ttccttttat ggggaattta ttttggaacc ttgctgttat
    49021 tagaaaaatt cattttgaaa cgatggctgg aacggcttcc cgcttggata cagcatggct
    49081 atacatgtct gctcgtcctg ttgggatggg tattgtttgc atttgaagat atgaatgccg
    49141 gatttgtcta cctgacccag atggccggag gcgccgatct tcctctctgg aatgacagaa
    49201 ctttattcct cctgtggggc agtctcattc tgctgctggc ctgcacaatc ggctccacac
    49261 cgcttcctgc tgcagcagcc aaaaagctgt gttcagacat ccagggaaag cttaaaactg
    49321 caggacttgt tctggaacct ctttttttag gcctggtgtg ctttctgtct gttgcctacc
    49381 tggtaaatgc cacctacaac ccgtttttat atttccgctt ttaacgcggc cagaaggaac
    49441 ctattatgaa aaaacaatca ctttatccgg ctgttgtaac cggtcttttc tgtgcttttc
    49501 tgggctgcgg cgctctctta tccgtcctga tgcctaagaa aagcttttct gaaacggaga
    49561 accgctatct ggcacagctg cccatatttt cctgggaacg cctggcagac ggcacattcg
    49621 gcacagatta tgaaaaatac ttaagcgatc agttcccgtt ccgcgacagc tggatcgggg
    49681 taaaaacagc ggctgaacag cttcagatga aaaaagaaat taacggggta tggctgggag
    49741 ccgatcaatt tctgttcgaa gccctctatc cggaagatat tgacaaggtt ctgtatgaaa
    49801 aaaatgtgaa acggctgtct gcttttgccc aggcacagga agagcttctc ggatcctccc
    49861 atgtccgtat tatgctgatt ccctcagcat ctcaaatcct cacagaacag ctgcctgcat
    49921 ttgccagccc gtttcagcag aatcagcttg tcactgattt agagaacagt gggatttctt
    49981 ctttgatggt tcccgttcaa agtgctctgg cctctgccca ttctgaaact cacccatcag
    50041 acagggagct ctactaccgg accgatcacc actggacctc tcccggggct tatgtcggct
    50101 acaaagcctg ggctgattcc atgggattta aacctttatc tccatctgac tttacggtag
    50161 agactgtttc cggaaatttt ctgggaacga ttcattctaa gctgaatctc cctatcaaac
    50221 cggattccat cgagctttac cggcccttag aggaacctga atggagtgtg tactatgatg
    50281 gatccagcga accatcccac agcctctatt cgatgaaagc tctgcagacc cgcgatcaat
    50341 accgggtatt tctggacgga aatcatggct ggacaaagat tgaaaatcct gcccagccat
    50401 ctgataaaaa gctgttgatt ctaaaagatt cctacgccca cagctttgct ccctttgccg
    50461 ctctccattt cggggaaacc catatggtgg atcttcggta ttttaatgga aaaatcagca
    50521 gctttatcag ggatcagggc attacagatc ttctggttct gtaccatatg cccggattta
    50581 tgaaggatgc caatatcagc aagctggggt ggtaaaattc agcctgtttt ttacttctgg
    50641 aatactccct ggtattccca ggtaacgccc tgatcctctg actgaaacat aaaaccgtct
    50701 gtctctgctt cctcggaggt aactcttata agcagcttct ccccctcctg ttttggcata
    50761 ctcagataat cataatcttc catagccagg ccatattctt ctgcagtttt cggaagctct
    50821 gttacctggt caaatggaag ttctgtcatt tcaaaggata cgcctccatc ccgcgtcagg
    50881 tatatggacg aatgggagcg ggacgcaccg gtaagccctg ctgccccgaa attttcatca
    50941 aaaaactgca gcccctccgc tgcccctatc tggccgccaa atggatctgc attggcacag
    51001 ttccaggtgc ttcctccgtc cgtcgtctga tccagctggt aaaatctgct tcccgccgct
    51061 gcgccggcta cagacaagcg ccatcccttt tgatcattca ggaaaaaata catggtttct
    51121 gtgctgcgat ctatcgtcca gccgtcttcc tccttagcct tctctgcctg aaggaccgta
    51181 ttctcctgag ccagttctgc ctggctgata tactccggct ccatgatgta ccggaccggt
    51241 gtgataccgg attcttccgg aatgtgcagt gacacctcga atccggctat ttctccgcca
    51301 ttctgaagca tatggaagct tcctgttcct gtttctgttc catctccgtc tgcatctcct
    51361 gaaacatact ccaatccctc tgaggaatga aatgctctcc gtcccagata cagaagctca
    51421 taaatctgct gctctcccag agtgtctgac cacaccttta cctgtccttc ccaatctgcc
    51481 tttttcagga tttcaagcat gggagacaaa agcttgtcgg aatcatatgc agcatctgta
    51541 ttctgatctg tccagaccgt catcgtttct ccgtcgtctg cgtcataatc tatgagatag
    51601 gtattcgtct gcccgttttt atcttttcca taaatcaaag tatctaactc ttgaatggtt
    51661 cccgtttcat caaaccctgt ctggaattgg ccagaaatat aaagctcctc cggcaaaccc
    51721 agcgcctcgt ccagatctgc cagaatccct tctataccag attcaaatat attgttatgt
    51781 ttgaaactga tctgcttttt attctgccac tcctctatct tccatgacaa tgctccatga
    51841 tatgggatcg ctgagtagat tattttccct gcaaagaaaa cagatgatgt aataaaaagg
    51901 aacatctcca gccagaatat tgtacttcta ttctgcttct ctgattccgt ttttctgcat
    51961 tttttcctcg ccgccagcca taaaaccagc gttccaacgc atcctgctgt ccctaaagcc
    52021 aaagccggta tatggcttct cacaccgcca tactggcaca gatgccacag acgctgcagg
    52081 gtaaaaatgt aacataccag acttattttt ccagataatg cataaatata ttgcatactg
    52141 acaccttttc ttttgtttta ttcatatttg tggttcgttt cccttttttc ttatgcctat
    52201 tatactatag aacgccatat taaaacagtc tttttctcag cctccccgcg taatatcctg
    52261 cttctgatac cactccagcg ctttcgaaaa atcctctggc tgaaaatcag gccacagtcc
    52321 atcaaccaca tagaaatctg cgtagacaga ctgcacaggc aaaaagccgg acagccgcct
    52381 catgcctccc caccggataa tcagatcgat tcgggaaata tcatgagact caagctgtct
    52441 gcagatgctc attctccggc tgcctggagc ctttaatttt gccagatccc actcccatcc
    52501 atagttcaca aggaaattca gacggattcc tcctccgttg aagtctgtcc tccttgtata
    52561 tggcagcaac gctttcggaa atgcaggaga ttcctggttt cccactacca gaagtgatac
    52621 cgattctgcc gtaatccagt taatcgcctc gacgcaggcc tttgaaaagg cttccacctg
    52681 ttccttagga cgtccgcagt tatctgtagt aaaaccatag taggtaatct cttccactcc
    52741 tgcatttttt gccagtttca gcatgtccag tcctggcttt aatccatgtg catagccgtc
    52801 ctgtttttcc agccctgcgc gctttgccca ccgtctgttt ccatctggaa taattccaat
    52861 atgttttgga atacgcatat catcactctc ctcctggtga gtattgacag atttggcaga
    52921 ggttatacaa tgacctgcac actacttcag aggcctgatg ctcgcccacg cagtaaaatt
    52981 ctgaaataca atatcccctc aaactcccga tgaaatttga ggggacaaac gattaataac
    53041 tctctttacc ttctgttcga tttacaattg ctgctccatt gctggttcca agacgtttac
    53101 agcccagttc tatatagtgg acagcatctt ctaaagtacg aattcctcct gacgccttca
    53161 ttcctgctgg ttttttcagg tattttctga aaagctctat atctttaaaa tcagcccctc
    53221 gtgaaccata tcctgttgac gttttaatga aatcagctcc tgtattttcg actattctgc
    53281 acattgctgc aatctgagct tcattgagaa agcatgtctc aattataact tttataatca
    53341 ccctatgctg atgacataaa tctgtaagag cctggacttc ttcctcaaca taggcttcat
    53401 ttccttctac aagctttcct atattgataa ccatgtcgat ctcttcagcg ccattcctga
    53461 ttgcttcttt tgcctcaaac agcttaactg ccgttgtatg tgtaccaaaa ggaaatccaa
    53521 taacgctgca agcttttact tcactttctc caagctcttg tgctgccagt ctgatattgc
    53581 atggattgac acaaacagat gcaaaatgat actctttcgc ctctctgcat gtttcaataa
    53641 tatcctgttc tgatgcaaaa ggctttaaat atgtgtgatc gatatactga ttaattttca
    53701 tatttgtatc cctttttaac tttatttttc cagtaatgcc ttagtctgat tcgaaattgc
    53761 agctactgcc tgctctggtg tataaccttc catttcaatg catcgctgaa tttctgtcat
    53821 catgatctct gaatgaatct gtggataatc ctcattaata ggtcttggaa tatctgtata
    53881 ctgcatttgt tcaagtgctg tcttcgctgc tgcattatca gctataaact cctgatatac
    53941 agaagactct gaggccgctt cgctgctcgg aacatatcct gtctggacag accagtatgc
    54001 tgctatatcc ggacttgtca gatacttaag aaaatccatt actgcttctg tatcttcctc
    54061 atggccggcc agcataacaa cattagcccc tccggtcggt acaccaaagc gtttatcttt
    54121 cggaaggaat gcagttccaa tttcaaactc acatgaattg gtaagtgttc caaggtctcc
    54181 ggatgaggta acaatcattc ctgtaattcc tgctgcaaaa tctgagcggg ctgcctcata
    54241 agaattatac tcttttcctg gcggtgcctt cataacacct tcttctatca tactcttcca
    54301 aagtgccagc ggttttgttc ctgtctcatt gttgaaccct atatctgttt catcctcatt
    54361 gagaatacgt ccatctccct gcatgataaa tgcttcatag aaccaggcat caatgggcat
    54421 ctcaaatccc catctctggt tgggaataga aagctttgat gcatattccc tcagctcatc
    54481 ccatgtttga ggtggtgttt ccggatccag gcctgcttct tcaaacatgt ccttgttata
    54541 gtaaaacatt ggggtacttc tgttaaacgg aagcgcatat aaaccttctc cccagtcgca
    54601 gcaatccatc agaccatcat aaaacatctc tggatcgagt cctgcttccc tggctggctc
    54661 tgtcatatcc tgaagcactc cataatctgc aaacatcttt gtacgtccca tttcaagctg
    54721 ggcaatgtga ggtgcttctc ctgatgtgac cgctgtctgc agttttgcag ccatatcgta
    54781 ataattaccc tgaaattcca ctgttacatg aaccttatcc tggctttcat tataatcctt
    54841 aactatctta tctactgtct ctcccattcc tccgctcatg cttgtccaga ataccacatc
    54901 tgtcttttca ttagcttcag atactactcc tccttccgaa gttgatgccg cttcatcctt
    54961 tgcagcactg catcccgtca tcaggctgcc tgccatcaga agacccagcc ctattgctgt
    55021 accttttttc atagtaaaaa tttcctttcc ctttttattt taatagttct tctattgcac
    55081 ttccctttgc ctctggcatc tcaaagccaa gaagctttgc aaatgtaggt gcttcgtcta
    55141 taatacactt tctttccaca atcacacctt cccggatatc aggtcctgcc atcataaata
    55201 ccggctgagg gccctttgac ggaagatgtc cgtgagaggc aactgaaaat ttgtaatctg
    55261 aattatccgg tctttctata accgtaccag tccaccgatt cccaaagctg gtattctgtc
    55321 cctctaaaac atattcaaac tcacctgcaa ggtgctgttc ccttctcacc tcttccttat
    55381 gaaaaactga ctctatacca tattccggag tcgctctcat tttatacaga agctcttcca
    55441 gctttttcct ggtcactgaa tcgtctggat tcttcataac aatctggcag gaaagagagg
    55501 tggaattaca gtaggcatcc cagtcacgga tcgttccatc ctctccaacc cggatcaaac
    55561 ctgcctgaac aaacagtaca ttaggatgaa acacctgctt aaccggaaga tgaccatgat
    55621 cactgatgac agcaaagttt gtatcatcat aaattccagc atccatagct gcttccataa
    55681 ggcgtcccag ccagtcatca tttgcaatta cagcctgggt aatggctgat ccctgaatgc
    55741 cgtttgcatg ccttgtatga tccagatgtg ccagatgtat aaacatgacg tctggctgat
    55801 accttcttat aatatcgcag gcacatccaa ccatcatctg atccataaat ggctgtgtcg
    55861 tccttctgag cttatgccag tgtctctcaa ggatcccatt ctccccaaac atattttcac
    55921 tgcaggcagt tttgagaatg tctcttggat ccactctgtc attttccggc catatctcag
    55981 gtacaagcca gtcaatttcc ggatttgcac ccatacacgg ccatccaatg caggctgttg
    56041 tgaacccctg cctatgcgcc aggtcaagta tggtaggaac cttgagatct ttatgatacc
    56101 agaaccaatc cggagccgga tttcccacat ctaacttttc attatgataa atgccatgaa
    56161 attccggcca ggttcctgta ataatcgaag catgggccgg atatgtaaat gacggatata
    56221 cgcttcgcat ccctccctgg gcataagccc ctctctctaa tattttcttg aaattaggaa
    56281 gtgtcttaag atactccata tcttcatcaa aaagagaat
//
LOCUS       DBMDUW010000012        49193 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_664_length_49193_cov_3.225251, whole genome shotgun sequence.
ACCESSION   DBMDUW010000012 DBMDUW010000000
VERSION     DBMDUW010000012.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 49193)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 49193)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49193
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_664_length_49193_cov_3.225251"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..234)
                     /locus_tag="ACZPCR_04095"
     CDS             complement(<1..234)
                     /locus_tag="ACZPCR_04095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009219940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HIR1230088.1"
                     /translation="MATIRDIAERAQVSISTVSRVLNYDETLSVNAATKKRIFEIAEE
                     LEYRGKNQKKRKRRLSLLLINYYSLEGEVEDPYY"
     gene            complement(275..3280)
                     /locus_tag="ACZPCR_04100"
     CDS             complement(275..3280)
                     /locus_tag="ACZPCR_04100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 TIM barrel-domain
                     containing protein"
                     /protein_id="HIR1230089.1"
                     /translation="MQMRAKKRWEDQTLTGINRRPGRTSFFTNSAEQVSLNGSWAFKY
                     LTAPEYSPEGFEKRDYDTAGWDTIEVPSCWQLKGYDHMHYTDVLYLFPLNPPYVPTEN
                     PTGIYKRSFEIPENWMENDTILRFEGVDSAYDVWVNGEHVGFSKVSRLPAEFDISSYI
                     NKGENQVTVRVYKWSDGTYLEDQDMWWFSGIYRNVSLISAPKARIKDCRIHADLDDSY
                     TTGLFDAQIRLAGEGILKWVLADAEGVTAASGEAEAGESASISARLESVRTWTAETPY
                     LYTLTLSMEQNGAVSHQVSYRLGFRRVEVKGNVFTVNGKAVLINGVNHHDYSPEGGRT
                     VDLEVMRQDVLLMKQHNINAIRFSHYPSIEAIYDFCDEYGMYVIDEADLECHGFEWAH
                     VYDMITDDPSWENAYVDRAVRMVERDYNHPSIIMWSLGNESCFGVNFKKEAEAVRAMD
                     SSRLIHYEGDFEAEITDVYSTMYSRLKGLKEIGETKMKHNRPHIHCEYSHAMGNGPGC
                     LADYQKLYRTYDRLQGGFIWEWYDHGIKKTDENGTVTYKYGGNYGDFPTNGNFCIDGL
                     LMPDRTPSPGLVEYKQVICPVWMERLGETGDLFAVKNYYDFKTLDGIYLECSVTDGKE
                     TIETFTIDSLHTEPGVEEILMIPHSAAEWKDNRDYYLNISVREKKETAWAPAGHELGH
                     YQFPLSEKKTVSVKREELPVSVSETATGVSISCQDVVYSFDKVHGVLSSMKKGGQELV
                     KRGPVLTVDRADIDNDMYKVNDWKNNYFISRGMEEMEYMTVSSGQNKAQVYIQKHFGC
                     YNQVWGFKLAYVYTVYGDGSMETELHGTAIRNPEFEPEFLPRIGVEMNVNGAFRHVAW
                     YGMGPGENYCDSRQAAVMGVYETDVDGMHTNYVMPQENGHRENVRWVSLTDEKEGLLI
                     TSRGGVGINVHDYTTEALRSAAHPCEIKKQDDIVLNLDWKHSGLGSNSCGQEQTEECK
                     VRIEDFAMSFALSFTEREKAEERAFTVFC"
     gene            3534..4826
                     /locus_tag="ACZPCR_04105"
     CDS             3534..4826
                     /locus_tag="ACZPCR_04105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009428345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIR1230090.1"
                     /translation="MKKTKLFVSAAAISMVAALSLTGCGGGGDKNAAESDNTITVWAW
                     DVALKQLQASAEKFKETHPDVEFQFEEMGTEQIYTKLATTLNTGKGLADVILLEGEQV
                     SGYASKYPDGFADLSDIVNKDDYLPVKMGEVTVNDKVVGFPWDAGPVALFYRTDYFEQ
                     AGVNPEDIKTWDDFIEAGKKVTATCKTPSGEPVKMLPIAPNGSNFWKLLLTEKGAGYF
                     DAEGNTAVNSPEALECMEMAKKIYDADIALNYTDWAEYEGVVVNQSVATIPEAVWMIG
                     TIKDKGPDQSGKWGVMSLPVFPGDEPSGSTNGGSDIVIPAASANVDIAKEFVQFAMTD
                     VDLQADGFVNYGLFPSYIPAYDAEVFTEPDEFFGGQKIYETFIELGKKVPAVNYTENY
                     NEAMKAAGSACAKVYLEGQDPKTVLEDLEKDLVSKFGK"
     gene            4857..5720
                     /locus_tag="ACZPCR_04110"
     CDS             4857..5720
                     /locus_tag="ACZPCR_04110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009429965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HIR1230091.1"
                     /translation="MKTRKKAKFFPYGMMMPTIVIFGLFMIYPVVYSFYLSFMEFSGG
                     TYTFVGLQNYIELFKDPVFYKALFNTFFYLIIQVPVMIGLALLLAVLIEQKFIRGRGF
                     FRMATFLPTITSLVAYALVFKVLFNTDHGLINYIVEFFGGEKIQWVYSAWPARASIII
                     SITWRWVGYNMIIILAGIQAIPTEMYESASLDGANFWQQLRYITIPAIKPILLFTTIT
                     STIGTLQLFDEPYILTQGGPNYATITLGEYLYDNGFKFLKFGFASALGYVMVIIIGIL
                     SYIQFRMNKED"
     gene            5722..6537
                     /locus_tag="ACZPCR_04115"
     CDS             5722..6537
                     /locus_tag="ACZPCR_04115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009429306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HIR1230092.1"
                     /translation="MLKKIGVYAFLILAAFLSLFPFYFMFVSGTNTNAEILAAPPKLL
                     PGSMLSHNFSILVEKMDIFRVAFNTLFISVVFTVLALMLYSAAGYVLAKFDFKGKGLI
                     FSFIMVSMMIPPQVMYVPLFQLFVATGMTNTYTAVILPALANAFGIFLMRQNMMNFPT
                     ALVEAARIDGYSEFGIFCRIVLPNVKPALSALVIYMFTSMWNNFMWPLIVLETKDMYN
                     FPVALAVLDGNPTNKDFAVILLATAIATLPILIIFMVFQKQFVAGVMGGAVKE"
     gene            complement(6664..7686)
                     /locus_tag="ACZPCR_04120"
     CDS             complement(6664..7686)
                     /locus_tag="ACZPCR_04120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002600120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HIR1230093.1"
                     /translation="MEHEVFLNRLLDAVTVSGEIAQGSQIVKEEMEPFADQVFTDILN
                     DTVAVLNPQAEPKILATAHLDEIGLVITCADEHGYLYAIDRGGVIPQTYPGHKVQIHT
                     EHGMVKGVVNGSRALCRKEKMEVTDLVIDIGADSKEEALSLVKPGSTVTFDCGFEKLS
                     GGRFAGRALDDRLGVYIIMEAFKRVKEAGTKRGVYCAATAGEETTKNGAYFTAGTVKP
                     DLAVVVDVTYCTDYPYGYSVKEAGEVKLGAGPVLCNSPLIPSQLNRQAEKIAARRGIP
                     VQYETASRLTCTDADKIHFENGGTPVILVSIPLRYMHSPAEVADERDVEGCIGLVAGI
                     LEEFEL"
     gene            7861..8967
                     /locus_tag="ACZPCR_04125"
     CDS             7861..8967
                     /locus_tag="ACZPCR_04125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002564564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HIR1230094.1"
                     /translation="MTPSNVYFTTFRTSFRENLLQKLERLIKKAGLFEQVDFQNKYAA
                     IKIHFGEPGNLAYLRPNYSKVLADLIKEHGGKPFLTDCNTLYIGGRKNALDHLDSAYT
                     NGYNPFTTGCHILIADGLKGTDEALVPVDGEYVKEAKIGQAIMDADIFISLNHFKGHE
                     STGFGGAIKNIGMGCGSRAGKMEMHNATSPFILQDKCIGCHACERNCAHGAISFQEKK
                     AFIDENRCVGCGRCIGVCPVDAVANHCDESNDILNKKIAEYTLAVVKDRPHFHISLVV
                     DVSPYCDCHAENDVPIVPNVGMFASFDPVALDMACADAVNRQPVMAGSVLSEREHCHH
                     DHFTDVHPETNWMVALEHAEKLRIGTREYNLITI"
     gene            complement(9294..10202)
                     /locus_tag="ACZPCR_04130"
     CDS             complement(9294..10202)
                     /locus_tag="ACZPCR_04130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006427357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium metabolism-associated LysR family
                     transcriptional regulator"
                     /protein_id="HIR1230095.1"
                     /translation="MNLKQLEAFVEVAESGSFSKAAKRLFLTQPTVSAHILALEKELD
                     IRLFVRNTKEVCLTEEGQRLYFYARQMADLQYKIKEEFGHRKTEEKQCIAIAASTVPA
                     QYLLPELLAKFNEKYPGEQLRIREMDSAQVVEQVSEHKADIGFTGTVLEKKHCRYIPF
                     YRDEMVIIAPNSGRYQAIDRTSGDISWICQEAMLMREEGSGTRKEAERQLAELGILPQ
                     QLNIMASIGNQETIKKSVIQGLGISILSNLAVREEVEDGRLLAFPVPSKRSGRDINVV
                     YNKNYQLSKSAKRFLRTVKEAYKVKE"
     gene            complement(10269..11312)
                     /gene="selD"
                     /locus_tag="ACZPCR_04135"
     CDS             complement(10269..11312)
                     /gene="selD"
                     /locus_tag="ACZPCR_04135"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013176491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004756 - selenide, water dikinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0001887 - selenium compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:complement(11265..11267),aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HIR1230096.1"
                     /translation="MKQNVRLTTLSKTSGUAAKIGPETLAQVLGKLPKFHDDNLLVGI
                     ETSDDAAIYKITDEIAMIQTVDFFTPIVDDPYMFGQIAAANSLSDVWAMGGEPAVALN
                     IVGFPNCLDPGILGDILAGGADKVKEAGAVLVGGHSVQDDEPKYGLCVSGFVHPQKIF
                     KNYGCKPGDVLVLTKQIGSGIVNTAIKAELASASAVQEAQTVMASLNQKAKRAADRCC
                     ISACTDITGFGLLGHCAEMASASGVTFELKVNDIAYFQDAVEYAKMGLVPAGTYKNRG
                     YSIGSVDAQGIEEFYLDLLYDPQTSGGLLLSVAREDLGTLLSELKASGIDTAVSVIGS
                     VAPESDKLIRLLK"
     gene            complement(11409..11591)
                     /gene="rpmF"
                     /locus_tag="ACZPCR_04140"
     CDS             complement(11409..11591)
                     /gene="rpmF"
                     /locus_tag="ACZPCR_04140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HIR1230097.1"
                     /translation="MSICPKNKSSKARRDSRRANWKMSAPNLVKCSKCGALMMPHRVC
                     KACGSYNKKEIIKVED"
     gene            complement(11594..12121)
                     /locus_tag="ACZPCR_04145"
     CDS             complement(11594..12121)
                     /locus_tag="ACZPCR_04145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceD family protein"
                     /protein_id="HIR1230098.1"
                     /translation="MLINLSELFTCEGKKKVYDAEIGLTEVSIGGEDYRVVSAEPFQL
                     TVTNTGDRKYFLEGSTKVTVEIPCSRCLEPVAYVCELTLDRELETDKPEAGQAEDLDE
                     QPYLSGYNLDVDQLALNEILIGLPMKVLCREDCKGICNRCGTNLNYGTCTCDRTSLDP
                     RMAVIQDIYKQFKEV"
     gene            complement(12209..13399)
                     /locus_tag="ACZPCR_04150"
     CDS             complement(12209..13399)
                     /locus_tag="ACZPCR_04150"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002573148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HIR1230099.1"
                     /translation="MNILVINCGSSSLKYQLINSETEDVLAKGLCERIGIDGILTYQP
                     ADGEKEKSEKAMPTHTEAIKFVLEALTNEKTGVIKSLSEVGAVGHRIVHGGEKFTAST
                     VLTAETIKAIEECSDLAPLHNPANLIGVRACQELMPNVPMVAVFDTAFHQTMPKTAYL
                     YGLPYEYYENYKVRRYGFHGTSHSFVSKRTAEIIGKPYEDCKIIVCHLGNGASLSAVM
                     NGKSVDTSMGLTPLEGLVMGTRSGDIDPAIIEFVAKKEGKTLDEMMNVLNKKSGMLGI
                     SCLSSDGRDLEQAAEKGDDKAQAALDIFAYRVIKYVGAYAAAMNGVDAIVFTAGIGEN
                     DAACRSKVCKSLTYLGAEIDEELNKCRGVERIISTPESKVKLLVVPTNEELAIARETL
                     ALVK"
     gene            complement(13444..14445)
                     /gene="pta"
                     /locus_tag="ACZPCR_04155"
     CDS             complement(13444..14445)
                     /gene="pta"
                     /locus_tag="ACZPCR_04155"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008398001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - pyruvate decarboxylation to
                     acetyl-CoA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HIR1230100.1"
                     /translation="MAFIDLMKAKAKQDKQTIVLPESKDKRTLIAAAQILQEGTADLI
                     MVGKEEKIMDGAGWLEVDLTGLKVVDPDTDPKFDHYAETLFELRKHKGMTKEKAEELL
                     KTDYITYGVMMVKEKDADGLVAGACHATADTLRPALQILKTAPGTELVSGFFIMDVPN
                     CEYGSNGTFLFADCGLNQDPNSEELAAIADSSAKSFRALIGEKPIIAMLSHSTKGSAK
                     HALVDKVTKAVEIAHEKYPQLDLDGELQLDAALVPEVAKSKAKGSPVAGHANVLIFPN
                     LDCGNIGYKLVQRLAKAEAYGPMLQGISRPVNDLSRGCSAEDIVGVVALTAVQAQMS"
     gene            14715..15971
                     /locus_tag="ACZPCR_04160"
     CDS             14715..15971
                     /locus_tag="ACZPCR_04160"
                     /EC_number="6.3.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(Met) cytidine acetate ligase"
                     /protein_id="HIR1230101.1"
                     /translation="MHVTGLITEYNPFHNGHLFHLKKARESTGADYTAVVMSGSFVQR
                     GAPAVFDKYSRTRAALLSGADLVFEMPAPFSTASAREFASYAVALFTALGAVDSICFG
                     SECGEIEPILRAARLLNEESESFKKRLQDFLKEGKTFPEARSSALAEEGAEEAKLLSS
                     PNNILGVEYCQAVLRQRSPLSCFTIKREGKGYHDPSLDGVLGSALAVRQALQSGTDVQ
                     ALRFLLPDPSFDSVCRSIPVFLDDFSGLLNYRLLTEQEPERYAEIRPELAARIKKLAP
                     GFASFDQRIKELKSRQLTYTGVSRGLIHLILGIEQRQMDLFKEAGFAPYARILGFRKS
                     AAPLLRRIKENSSIPVIIKLAGAEKRLDPAGAAMLACEIQSSHLYQNVRCEKAASGAF
                     PGRTAVFQNEYTQPVLILDQETSLLL"
     gene            complement(15936..17180)
                     /locus_tag="ACZPCR_04165"
     CDS             complement(15936..17180)
                     /locus_tag="ACZPCR_04165"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HIR1230102.1"
                     /translation="MEQGHKLDETFAFFLNEKLDRIILSNPRTRDGYVKLILRPLILQ
                     GRLKFQAEEFTEKQAFHKNMSAREAAEYLKDQLSKLYRNGEIFSLLGSGTILVGKKGT
                     VTVKIKKKVVLAAPDKKAEKTVQTGRTKAADISPEDLARLSRHNRAKHYVLPEGTPVP
                     FLVDLGVMTKDGAVVKAKYDKFRQINRFLEFVEDILPRLDRSKETRIIDFGCGKSYLT
                     FAMYYYLKEVKGYPVRITGLDLKKDVIALCSRLAKKFGFENLTFLHGDIADYEGADQV
                     DMVVTLHACDTATDYALAKAVRWGAKVILSVPCCQHELNGQIESSLLAPALKYGLIKE
                     RMSALLTDAVRAGLLEEAGYRTQILEFIDMEHTPKNILIRAVRQGKPQKQQGLSELIE
                     ELHAEPALLRLLKEQGSLLVQD"
     gene            complement(17197..18561)
                     /locus_tag="ACZPCR_04170"
     CDS             complement(17197..18561)
                     /locus_tag="ACZPCR_04170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009268286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF711 family protein"
                     /protein_id="HIR1230103.1"
                     /translation="MINMLEVNETNNMIDNEKLDVRTITMGISLLDCAASTVEELNEK
                     IYRKITSYARDLVSTGDAIGREFGVPIVNKRISVTPIALVGGSACKTEADFVSIAKTL
                     DQAAREVGVNFIGGYSALVSKGMTRADELLIRSIPQALASTERVCSSVNVGSTKCGLN
                     MDAVRLMGEVVLETAKATKDQDSLGCAKLVVFCNAPDDNPFMAGAFHGVTEAEAIINV
                     GVSGPGVVKTALEKVRRENFEVLCETIKKTAFKITRVGQLVAQEAAKRLGVPFGIIDL
                     SLAPTPAVGDSVAEILEEIGLERVGAPGTTAALAMLNDQVKKGGIMASSYVGGLSGAF
                     IPVSEDQGMIDAVTLGALTIEKLEAMTCVCSVGLDMIAVPGDTSAATISGIIADEAAI
                     GMINQKTTAVRLIPVIGKQIGDTVEFGGLLGYAPVMPVNRFKCEDFISRTGRIPAPVH
                     SFKN"
     gene            complement(18592..18864)
                     /locus_tag="ACZPCR_04175"
     CDS             complement(18592..18864)
                     /locus_tag="ACZPCR_04175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002564335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HIR1230104.1"
                     /translation="MSRIIISVIGKNDVGMAANICTYLAESNINILDITQTIVKEIFD
                     MMMIVDIARSPKSFDEIAGEMDELGQRIGASIRCQREEIFTSMHRI"
     gene            complement(18906..19703)
                     /locus_tag="ACZPCR_04180"
     CDS             complement(18906..19703)
                     /locus_tag="ACZPCR_04180"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013272554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HIR1230105.1"
                     /translation="MRMVSIASGSSGNCIYIGSDHTHLLVDAGISNKRIEQGLNDIGI
                     KGSELDGVLITHEHSDHVKGLGVLARKHGVPIYSTRETLEEIKTMKSLGDYPEELLRP
                     VAHDVDFFIGDLEIKPFKISHDAANPVAYRVQEGKKSVAVATDMGNYSQYTIDRLQGL
                     DAILLESNHDVKMLEAGPYPYYLKKRILGEYGHLSNDNAGRLLSCVLHDNLKHIFLGH
                     LSKENNYEELAYETVKLEIAESDTPYHSSDFPITVARRDAVSEIVTV"
     gene            complement(19700..20299)
                     /gene="coaE"
                     /locus_tag="ACZPCR_04185"
     CDS             complement(19700..20299)
                     /gene="coaE"
                     /locus_tag="ACZPCR_04185"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510613.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HIR1230106.1"
                     /translation="MRVIGITGGVGSGKSEILRLLKEEFGAKLLMADDIAHEVMAPGG
                     EASRRIEEAFGADYLKPDKSVDRQKMAELIFKDADALETMNSIVHPAVWRRIEEGIQT
                     ASEKLVAVEAALFDEEHNRMFDEVWYVYTSKENRISRLMASRGYSRKKCMDIMGNQRS
                     EEEFRAMADRIIDNNRTIEDVRQQIERILNEKMKEEAQA"
     gene            complement(20322..23036)
                     /gene="polA"
                     /locus_tag="ACZPCR_04190"
     CDS             complement(20322..23036)
                     /gene="polA"
                     /locus_tag="ACZPCR_04190"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002573156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HIR1230107.1"
                     /translation="MSKVVLIDGHSILNRAFYGVPELTNSKGLHTNAVYGFLNIMFRV
                     IEDEKADHLAVAFDLKEPTFRHKMYEAYKGTRKPMPEELREQVPVIKEVLSAMGIPIC
                     SLPGYEADDVLGTIAGRCAAAGAEVAIVSGDRDLLQLADEHVKIRMPKTTRGGTEIKD
                     YYPADVKEQYQVTPKEFVDVKALMGDASDNIPGVPSIGEKTATALITAYGSIENAYAH
                     IDEVKPPRAQKALREHYDMAQMSKELALICTDCPIEFSMEEAKMGNLYTPEAYQLLSQ
                     LEFKSLLLRFDADSRAENQEEKQFRAVSNLEEAAQLFERARKNGEAGVQLAVEAGEVL
                     ALGLAFGEQDIYCIHTSDTISGEYLTEQLNRLAEGGAGLSFLDLKSQLPFLPAADRLG
                     DCGEDTPDSRQLFDAGVAGYLLNPLKDTYDYDDLARDYLDMTVPSKGDLIGKQSFGDI
                     FSEITMDLGQEASENGKEELNSGEQCLCYMAYTAWKSRERLTEKLKETGMEELFFSIE
                     MPLIYSLFHMEQAGICVKREELQAYGERLRGQIETLEQEIYQGTGEVFNINSPKQLGE
                     ILFGKMELPYGKKTKTGYSTAADVLEKLAPEYPVVQKILDYRQLTKLKSTYADGLAGY
                     IRADGRIHGIFNQTVTATGRLSSTEPNLQNIPVRMELGREIRRVFVPQEGCVFVDADY
                     SQIELRVLAHLSGDERLIEAYKKAEDIHAITASEVFHVPLDQVTPLQRRNAKAVNFGI
                     VYGISAFGLSEDLSITRKEALEYINRYFETYPEVKKFLDRLVEEGKEHGYVTTMFGRR
                     RPVPELSSKNFMQRSFGERVAMNSPIQGTAADIIKIAMNRVDRRLRREGLKSRIVLQV
                     HDELLIETWKEELDTVRTVLSEEMKHAADLKVSLESDMKTGNSWFETK"
     gene            complement(23065..23400)
                     /locus_tag="ACZPCR_04195"
     CDS             complement(23065..23400)
                     /locus_tag="ACZPCR_04195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma factor family protein"
                     /protein_id="HIR1230108.1"
                     /translation="MTCQEAERLVTPYIRDELAGDELEAFLNHIDECPNCREELEIYF
                     MVDVGLRQLDHDSGTYDIAGDLEHKIEESYLKVSHMWMFRMFHYAVNTLGVMAVIVTA
                     LLQFRIWFY"
     gene            23594..23676
                     /locus_tag="ACZPCR_04200"
     tRNA            23594..23676
                     /locus_tag="ACZPCR_04200"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:23627..23629,aa:Leu,seq:caa)
     gene            complement(23881..25059)
                     /locus_tag="ACZPCR_04205"
     CDS             complement(23881..25059)
                     /locus_tag="ACZPCR_04205"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016296308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HIR1230109.1"
                     /translation="MNELELKYGCNPNQKPSRIFMENGSELPIKVLSGRPGYINFLDA
                     FNGWQLVSELKKATGLPAATSFKHVSPAGAAVGLPMDETLRKIYWVDDMGELSPIACA
                     YARARGADRMSSFGDFIALSDVCDADTAKLIKREVSDGIIAPGYTEEALAILKSKKNG
                     NYNVIEINQDYQPEKLERKQVYGITFEQGRNELDINKDMFTNIVTENKELPDSAKIDM
                     AVAMITLKYTQSNSVCYVKNGQAIGIGAGQQSRVHCTRLAGQKADNWFLRQAPQVLNL
                     KFVDGIKRADRDNAIDVYIGEEHMDVLAEGSWQRIFKEKPPVFSREEKREWLNQMQDV
                     TLGSDAFFPFGDNIERAHKSGVKYIAQPGGSVRDDNVIETCNKYGMVMAFTGIRLFHH
                     "
     gene            complement(25094..25810)
                     /locus_tag="ACZPCR_04210"
     CDS             complement(25094..25810)
                     /locus_tag="ACZPCR_04210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015540863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP cyclohydrolase"
                     /protein_id="HIR1230110.1"
                     /translation="MNKISLSEELKNNAYPGRGIVIGRSADGTKAVAAYFIMGRSENS
                     RNRVFVEEGDGIRTQAFDPSKLTDPSLIIYAPVRVLGNKTIVTNGDQTDTIYEGMDRQ
                     LTFEQSLRSREFEPDAPNYTPRISGIMHIENGSYNFAMSILKSDSGCPDSCLRYTYAY
                     EKPLAGEGRFIHTYMHDGNPLPSFEGEPKLVDIPDDMEAFAAMLWESLNPDNKVSLFV
                     RYIDIATGEKQTKIINKNMK"
     gene            26068..26871
                     /locus_tag="ACZPCR_04215"
     CDS             26068..26871
                     /locus_tag="ACZPCR_04215"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230111.1"
                     /translation="MRRKTLFLAALLLAMAVTGCRKKETIDLSTLHTTAAETENQSEK
                     EPSKEPIQLDTEHTESSSETEHKYSVDISMETYTDGGVSIQYPVLSSLSDQELQEKIN
                     QLIKENAVSAARAKGLPAEGASLTVSASVESSNLKRLVLSYKGELKKGADTERIFYSN
                     TIDLEEGRNLQLSDYADAYTVAGYLASGDYVFAEAPKGDETAVRAYINGAGRDTDYYY
                     KKLAEADFSETGAFPEYCSFERQGTIFVSVPVSHELGDYALIKYVPDNK"
     gene            26896..27525
                     /gene="upp"
                     /locus_tag="ACZPCR_04220"
     CDS             26896..27525
                     /gene="upp"
                     /locus_tag="ACZPCR_04220"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002564356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HIR1230112.1"
                     /translation="MENVTIFTHPLIQHKISILRKKETGTNEFRSLIEEIAMLMGYEA
                     LRDLPLEEVEVETPIETCMTPFLAGKKLAVVPILRAGLGMVNGILALVPSAKVGHIGL
                     YRDEVTHEPHEYYCKLPSPIDQRIIVVTDPMLATGGSAVEAVDFIKQHGGKSIKFMAI
                     IAAPEGLKRLHEAHPDIQIYVGHVDRCLNENAYICPGLGDAGDRIFGTK"
     gene            complement(27552..28232)
                     /locus_tag="ACZPCR_04225"
     CDS             complement(27552..28232)
                     /locus_tag="ACZPCR_04225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LbetaH domain-containing protein"
                     /protein_id="HIR1230113.1"
                     /translation="MKKQDMKIEKLYDLTHTMAGEYLSGFEYPWEALEGISAFLTELG
                     NTLPEEEFEKRGENIWIHKEAKVAPTAFLNGPLIVCRGAEIRHCAFVRGSALVGEGAV
                     VGNSTELKNVILFDKVQVPHYNYVGDSILGYKSHMGAGSITSNVKSDKLLVKIHGEDG
                     EIETGRKKVGAMLGDQVEVGCGSVLNPGTVIGRESNIYPLSSVRGCVSEKSIYKRLGE
                     VAEKKEER"
     gene            complement(28232..30337)
                     /locus_tag="ACZPCR_04230"
     CDS             complement(28232..30337)
                     /locus_tag="ACZPCR_04230"
                     /EC_number="5.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HIR1230114.1"
                     /translation="MAKALYIAEKPSVAQEFARALKISGRRADGYIESETAVVTWCVG
                     HLVTMSYPEEYDARYKKWRLDTLPFLPKDFKYQVIDGVKKQYKIVSSLLKRSDIDTVY
                     VCTDSGREGEYIYRLVAQMAGVKGKQEKRVWIDSQTEEEILRGIREAKSLSEYDNLAA
                     SAYLRAKEDYLMGINFSRALTLKYGPAIANFMGSKWTVVSVGRVMTCVLGMAVRRERE
                     IRSFVKTPFYRVIGTFQQDGMDFQAEWKAAEGSRYFQSPALYRDNGFKEREKAEELIR
                     FLSEKPPMSGTVLSVEKKKETKNPPLLYNLAELQNDCSKLFKISPDQTLKVVQELYEK
                     KLVTYPRTDARVLSSAVAKEIAKNISGLRGFQPCAAFAEEVLAGGTWKTIGKTRYVND
                     KQITDHYAIVPTGQGMGALRSLSLLNAKVYERIVRRFLSIFYPAAVYRKYSVELLSQT
                     EHFFASFKLLKEPGYLKVSDVSRAGKNDGAEEAGKEKQPQAAESDAESWEKEGSQETV
                     IGNGAFAQMLEGLKKGTVLELKSLSVKEGETSPPKRYTSGSMILAMENAGQLIEDEEL
                     RAQIKGSGIGTSATRAEILKKLMSIHYLSLNAKTQVITPTLLGELIYEVVQASIRQLL
                     NPELTASWEKGLTYVAEGSITEAEYMEKLERFVAGRTYAAVHMANQAGLRRQFELAAQ
                     NYKTGSTKKAASAGKGEKK"
     gene            complement(30352..31233)
                     /locus_tag="ACZPCR_04235"
     CDS             complement(30352..31233)
                     /locus_tag="ACZPCR_04235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HIR1230115.1"
                     /translation="MDTKHMGMAKALAIAAFLAVTIIWGSTFVVMKNSIDMLSPAYVL
                     AYRFTIASLGLAVLFHRRLIHMNRRDLHCGIVLGVLLGMSYVFQTYGLQHTTASKNAF
                     ITTLYVIIVPFLHWVLNGVKPRKNNLTAAVLAVIGLAFISLNGEHGINLGDVLTFLCS
                     VFLAWHMVYVDRYTRHRDPVLLTVLQIMVSALLFWVLALATEGVRDVRELLDWQTAWP
                     LLYLGLIASMLGFLVQNVGQKYLSPNTASILLSFESVFGLIFSVIFLKETVTAKMLAG
                     CVLMFAAAVISEYRAGS"
     gene            complement(31341..32399)
                     /locus_tag="ACZPCR_04240"
     CDS             complement(31341..32399)
                     /locus_tag="ACZPCR_04240"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007857919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HIR1230116.1"
                     /translation="MPYTKEAFGQMPGGEAVHKYTLENKNGLTAGFLDLGAVWHSMLV
                     PDREGKFADVVLGYDSPEHYLASDAHLGEIIGRNANRIGGGRFELNGREYALTVNNGP
                     NNLHSGNDFYRNRLWEARTWEEADESSVCFTLESPDGDQGFPGNLKISVTYTLNDQDE
                     LHIRYQGVSDADTIMNMTNHAYFNLAGHQSGDAMGQQVYLNADQFTPADEVSIPYGTV
                     VPVKGTPMDFTEAKEIRQDLESGYDQLVKGNGYDHNWVINRDREGLALAAKAWDKESG
                     RVMEVWTDMPGVQFYTANYLDNSLPGKDGAVYGARRAYCFETQYYPDAVNHPQFPSPV
                     IKAGVEKQTKTVYRFCTE"
     gene            complement(32426..33517)
                     /gene="asd"
                     /locus_tag="ACZPCR_04245"
     CDS             complement(32426..33517)
                     /gene="asd"
                     /locus_tag="ACZPCR_04245"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013272543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HIR1230117.1"
                     /translation="MKKKLKVGVLGATGMVGQRFISLLAEHPWYEVVTVAASPRSAGK
                     TYEEAVGGRWKMKTPMPECVKSLVVMNVNEVEKVAAGVDFVFSAVDMTKDEIRAIEEA
                     YARTETPVVSNNSAHRWTPDVPMVIPEVNPEHFKVIEFQKKRLGTKRGFIAVKPNCSI
                     QSYAPVLSAWKEFEPYEVVATTYQAISGAGKTFKDWPEMVENIIPYIGGEEEKSEQEP
                     LRIWGEIKDGVIVKASEPVITCQCIRVPVLDGHTAAVFVKFRKKPSKEQLIEKLTAFK
                     GLPQELELPSAPKQFIQYLEEDNRPQVKLDVDFERGMGVSVGRLREDTVYDYKFVGLS
                     HNTLRGAAGGAVLCAELLTAQGYIQAKEQ"
     gene            complement(33637..35409)
                     /gene="ade"
                     /locus_tag="ACZPCR_04250"
     CDS             complement(33637..35409)
                     /gene="ade"
                     /locus_tag="ACZPCR_04250"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008397971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HIR1230118.1"
                     /translation="MMTLEPKNKKALLRTALGLEKADLAVVNCRLVNVFTGEIYPAVV
                     YVKDGFIAHVEDSCLEGPYDAETVYDGQGRYLIPGLIDSHMHIESSMMTPRNFAKAVI
                     PHGTTTIIHDPHEIANVYGREGVVYMHDAAEGLPMRQLVDIPSCVPAVPGCENAGAAF
                     MAEDIEALAELPRAVGLAEVMDFYGVMYGEDRMMEIIEAAGKKGLYLQGHAPAVTGRK
                     LSAYLIGGPATCHETTAGDEALKKLRSGMYVDARESSITKNVEAIWNGVKDIRFFDTL
                     TLCSDDRESDDLLHTGHLNAVVRKAVESGMGPVLAIKSATINTAREIGMEHLGAIAPG
                     YIADMVLTDDLRTMWAKAVFFEGQLAAEDGRLIAEIEERPFELENRNSMNVGELSLED
                     FCLKCPKNHGTAAVNVMEYKTRIQSHTICTVQEHEIRDGQLVLQENEAFVAVINRHGK
                     GTRAVGLVKNFGLREGAVASTVSHDSHNLTVVYFNPEDGLAAAEELIRCGGGMTAVKD
                     KTVLHTLPLEVAGLMTNLEAEELSRKASAMKEVERKLGLTDMENPLLRIVTLALPVIP
                     EVKMSDLGLVSVAERKLIPIFPEA"
     gene            complement(35559..36695)
                     /locus_tag="ACZPCR_04255"
     CDS             complement(35559..36695)
                     /locus_tag="ACZPCR_04255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family lipoprotein"
                     /protein_id="HIR1230119.1"
                     /translation="MRKLLKKAAAVTLTAAMAASLTACGGSGDGASKETGEAQAAGEN
                     GEKIKLTLCIGRKNDLSFQQSAYEGSLRIQEEMGDKYEVNVVEMGDDTTKWQAAFYDA
                     ADAGADIVVGTGFQNKENFETIPTEYPDTKFILFDQELDFESNDLPNTMGVLFDSNQS
                     GFLAGAVAAYYTTGENAANADKTIGFVGGVESTTVNNFLVGYAEGAKYVDPEIKVLTA
                     YVGDYMDTAKAKDLANAQISEGADIIFQVAGGAGNGVIEAAAEKDGVMAIGVDSDQYQ
                     ALEGSNLQPAVITSSLKRLDNALFNICQSYAEDPSSVPFGENVTYGLAEDSVGIVFND
                     NLTNSIGQENVDKVQEALEKIQVGEIEVTEAAGLSAEEIDAIVQ"
     gene            complement(36780..37694)
                     /locus_tag="ACZPCR_04260"
     CDS             complement(36780..37694)
                     /locus_tag="ACZPCR_04260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004461900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1230120.1"
                     /translation="MEFLVNLDFWFTVLRCTTPVLLATMAALIASRSGLLNLGLEGTM
                     TIAALCGVLGSGFTGSLFVGAAAGLLAGTVYTMLLAYFIQHLKANQVITGVALNLAAT
                     GGSVFCLYSLTGDKNASNSLPSQAFPAVNIPVIQDIPVVGDILSGHNCLTYLAFIVAV
                     VMFVMLKKTAFGIRIRAVGESAEAARSVGINVEKVRYQAMFISGILASLGGMYLSMGY
                     VNRFTSNMVAGRGYIALATNAMAAGNALMGTVSSILYGVGSGISIYLQNNNVDPYLIT
                     IIPYASIIIFYVAFSLYYKVRQKSEGGL"
     gene            complement(37707..38786)
                     /locus_tag="ACZPCR_04265"
     CDS             complement(37707..38786)
                     /locus_tag="ACZPCR_04265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1230121.1"
                     /translation="MNIKKKIDWYSVIRVATSILIALIIAAAIIFAVADDPMTALNRF
                     LLGPFSTKRNFFNAVEMMVPLVFCGLAINVMHKSGLFSMVADSSFYFSGVIAAILAIA
                     CPMPAGVHQLVILLTSMAVGGLIGVIPVIIKRKTGANELVISLMMNYIFFNFGYWLIR
                     AFFLDEANGSFSVKFQKTANLGKMIKGTNAHYGIFIMIAAVVFMWILMDKSKFGRELK
                     ITGSNPSFAKYAGLKIGGIVIGSQLIGGMLAGLGGGVEMIGMYTHFQWITAQTYVWDG
                     ILINLLAGTKPLMIPVSAFFISYIRIGALVMSRGGDVDSEIVSIIQGIIILLIASERF
                     MYQMKKRKEEKEALQNQAMETAGVN"
     gene            complement(38790..40331)
                     /locus_tag="ACZPCR_04270"
     CDS             complement(38790..40331)
                     /locus_tag="ACZPCR_04270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1230122.1"
                     /translation="MAEEILRVEDLTKIYPGGVLANYNINFSVNKGEIHALVGENGAG
                     KSTLMKMLFGIEEITSGKVFLHGEEVHFHSSKDAIEHGIGMVHQHMMLVPSLTVAENL
                     VLGIEKKKGLFLDQKKAVEETEAISQKYNLHVDAQKRVRDISIGMKQKLEILKTMYRG
                     AKIIILDEPTAVLAPQETEELFEQLLNLKKEGYTIIFISHKLNEVKYLCDRLTVLKDG
                     RSIGTYNLADITLEEISRLMVGRDVKLEYDKTSQEFGEKILKVENLNYTDKFGTKKLD
                     NLSFSLKAGEVLGIAGIEGNGQKEAMEILTGNRKAESGSVFYKGKDLTKLSITDNRKL
                     GIAHVPEDRNLNGCAPEMSVRDNLIATSLKRLSGKGSILKPEEIESYCGKCVEDFTVK
                     TMNLDISIKSLSGGNVQKAIVAREFTAGAEIIVLNQPTRGVDVGAMEFIHKKILEMRD
                     EKKSLILVSADLTELRALSDRIIVFHQGKVAGVINDVPAATEEELGLYMLGLKEDPAE
                     KLQEA"
     gene            complement(40359..41078)
                     /gene="deoD"
                     /locus_tag="ACZPCR_04275"
     CDS             complement(40359..41078)
                     /gene="deoD"
                     /locus_tag="ACZPCR_04275"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004461904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HIR1230123.1"
                     /translation="MEENRVPTPHIGAQAGEIAETILLPGDPLRAKYIADNFLTDVKQ
                     FNGVRNMFGYTGYYKGKRVSVMGTGMGCPSIGIYSYELIHFYGCKNLIRVGTAGALQE
                     NVKIRDLVIGMGACTTSNYVKQFRLPGDYSCICSFELLEKAVQAARNKGMNFHVGNIL
                     SSDMFYNPELPPVGLGWDKMGVLAVEMEAAALYSNAAAAGVNALCILTISDSAVTGEA
                     TTAEERQTTFTNMMEVALELA"
     gene            complement(41154..42446)
                     /locus_tag="ACZPCR_04280"
     CDS             complement(41154..42446)
                     /locus_tag="ACZPCR_04280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004180 - carboxypeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HIR1230124.1"
                     /translation="MKIGTAGSIVLTEEQKQELAELGHALFACPELGFKEVKSSGILT
                     SFLIKEEFSVETGLSVTGLKAGLGTGDGYHIALVADMDALEVRIQDQPCAFHSCGHSI
                     QTAVMAYAMKLLKERGIAEKSGGRVSFIAAPAEEFIDFDSRRAMQKEGKIQYFSGKQD
                     MIANGVFDDVDCVISMHVNGDSGELMFDVQSSLAGFAVKKAVFHGRASHSGAAPHLGR
                     NALHAASLAMNAIAYMKDQFPAEAGLQLHPVLTSCGGSVNVIPEEAVLETYIRANTLE
                     TLLEAEKKFDDCVLHCARALGMTAQVERTAGYMPLHQSEEISDVIHRQMLSLCREDQI
                     VKQVVSGASGDIGDLGYLIPSVQFGFSGISGRIHSAEFSISNEENAYFNTLKIVTAAV
                     EEILTHPELQVKNPDFSEKKNFYMKEWLRRPSEEKNME"
     gene            complement(42584..44827)
                     /locus_tag="ACZPCR_04285"
     CDS             complement(42584..44827)
                     /locus_tag="ACZPCR_04285"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006776103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009330 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) complex [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase/topoisomerase IV subunit A"
                     /protein_id="HIR1230125.1"
                     /translation="MSEKIIKTEYSEEMQRSYMNYSMSVITSRAIPDARDGLKPVQRR
                     VLYDMSELHLGHDKPHRKSARIVGDTMGKYHPHGDSSIYETLVVLSQMFKKGMPLVDG
                     HGNFGSIEGDGAAAMRYTEARLEKFAEEVYLKDLDKTVNFVPNYDETEKEPEVLPVRV
                     PNLLINGAEGIAVGMSTSIPPHNLGEVIDTVQAYIDNQEMDTASLLEYLHGPDFPTGG
                     IIANKKDLPAIYETGTGKIKLRARMEVELGKRKADKDKLVITEIPYTMIGAGINKCLM
                     DIADLVESKKLTDVVDISNQSNKEGIRIVLELRKDADIEKIKNILYKKTKLEDTYGVN
                     MLAIVKGRPETLNLRGILKNYLDFQYENNTRKYQVLLQKEQEKKEIQEGLIKACDIID
                     LIIAVLRGSKNLKDAKACLMEGDISKIQFRVPGFEEEAKKLCFTERQASAILEMRLYK
                     LIGLEILALEKEHKETLRKIREYEKILSSRDAMDQVIKEDLNSIKEEFSSPRRTGIED
                     GREAVYDESAVEVREVVFVMDRFGYSRILERSTYDRNQETVDSEHSHVVCCLNTDKIC
                     LFTDTGALHQVKVADIPLGKLRDKGTPIDNLCKYDGTKEEIVFLTNAAALPGHILLFA
                     TKGAMLKQVPGEEFETNNRMVAATKLADGDQVADIQMMDGAREAVLQTDHGVFLRFAA
                     EEIPVQKKNAKGVRGIKLSKEEQLETVYLLGENTDNIAVYKEKQVHLNRLKLSHRDGK
                     GSRTRLN"
     gene            complement(44896..46815)
                     /locus_tag="ACZPCR_04290"
     CDS             complement(44896..46815)
                     /locus_tag="ACZPCR_04290"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013272541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase/topoisomerase IV subunit B"
                     /protein_id="HIR1230126.1"
                     /translation="MGKSQYDADSITVLEGLEAVRKRPGMYIGGVGTKGLNHLIYEIV
                     DNSVDEHLAGACTSIWVTLESDGSCTVRDNGRGIPVEMHKKGVSAERVVLSTLHAGGK
                     FDNAAYKTSGGLHGVGSSVVNALSERLDIRIYKNGQIHHDAYRRGLPVVELVDGLLPV
                     IGKTKETGTSINFLPDDTIFEKTKFKAEWLKSRLHETAYLNPALTIHYENKRSGEEEQ
                     ITYSEPEGIVAYVKEINAGKTALHDPIYMKGTVDGIEVEAAIQFVDTFEENILGFCNN
                     IFTQEGGTHLAGFKTKFTMLINSYARELGILKEKDANFTGADTRNGMTAVIAVKHPDP
                     IFEGQTKTKLASADATKAVFTLAGDELQRFFDRNIETLKAVISCAEKSAKIRRAEEKA
                     KTNMLTKSRFSFDSNGKLANCESRDAEKCEIFIVEGDSAGGSAKMGRNRQYQAILPIR
                     GKILNVEKASMDKVLANAEIKTMINAFGCGFSEGYGNDFDITKLRYHKIILMTDADVD
                     GSHIDTLLLTFLYRFMPDLITEGHVYIAMPPLFKVIPKKGEEQYLYDEKALERYRKNH
                     TGSFTLQRYKGLGEMDAEQLWETTLNPENRVLKQVEIEDARMASEITEMLMGSDVPPR
                     RKFIYDHADEAEIDT"
     gene            complement(47002..48084)
                     /locus_tag="ACZPCR_04295"
     CDS             complement(47002..48084)
                     /locus_tag="ACZPCR_04295"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006780158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009101 - glycoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1230127.1"
                     /translation="MIVKDEEKVLKRCLDSAVSFADEIIIVDTGSSDSTKKIAETYTK
                     KVYDFTWNDDFSAARNEAFRHAEMDYCMWLDADDIVSEPEQEKIQRLKEELDDDTAIV
                     MMKYSMGFDKTGSPSLSYYRERLIKNHEGFCWQGKVHEAVALSGKILYTDIEIEHRKT
                     EKGKEGQRRNLSIYRKMKEEKVPFTARDLFYYGRELYYSAMESTECFRESQAVLTEFL
                     SRPDGWAENKIEACRFLALCRQAEGDEEGALASLLHSFFYDCPRAELCCDIGDWFFKR
                     EEYRTASFWYETALKAKTDERKGGFICPDCGGYIPALQLAVCSYRMGETEQAEQWNEL
                     ALRFKPESESCRYNRLFFRQQKEKSD"
     gene            48285..48358
                     /locus_tag="ACZPCR_04300"
     tRNA            48285..48358
                     /locus_tag="ACZPCR_04300"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48319..48321,aa:Pro,seq:cgg)
     gene            48363..48434
                     /locus_tag="ACZPCR_04305"
     tRNA            48363..48434
                     /locus_tag="ACZPCR_04305"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48396..48398,aa:Glu,seq:ctc)
     gene            complement(48482..49102)
                     /locus_tag="ACZPCR_04310"
                     /pseudo
     CDS             complement(48482..49102)
                     /locus_tag="ACZPCR_04310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006779193.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
BASE COUNT        11262 a        13908 c        10589 g        13434 t
ORIGIN      
        1 gtagtaggga tcctccacct ctccttccag tgaataatag ttgatcagga gaagagagag
       61 cctgcgtttc ctcttcttct ggttttttcc tctgtattcc aattcctctg cgatctcaaa
      121 tattctcttt ttcgtcgccg catttacgct cagagtttca tcataattca acacccttga
      181 cactgtgctg atagaaacct gcgccctctc tgctatgtcc ctgatcgtcg ccatatatgc
      241 ttcttcctat tctttctata atttaaatgc ctgattaaca gaagacagta aacgcccgtt
      301 cctctgcttt ctccctctct gtgaaagaaa gggcgaagct catggcaaag tcttcgattc
      361 ttaccttgca ctcctctgtc tgctcctgac cgcaggagtt gcttccaaga ccggaatgtt
      421 tccagtcaag attcaggaca atatcgtcct gttttttaat ttcgcatgga tgagccgcgc
      481 ttctgagcgc ctctgtggtg tagtcgtgaa cattgattcc gactccgcct ctggaggtaa
      541 tgagaagtcc ttctttctca tctgttaagg aaacccagcg cacgttctct ctgtggccgt
      601 tttcctgcgg catcacataa tttgtgtgca ttccgtccac atctgtctca tagacgccca
      661 tcactgctgc ctgtctggaa tcgcagtaat tttctcccgg gcccataccg taccaggcca
      721 catggcggaa cgctccattt acgttcatct ccacaccgat tctcggaagg aactccggct
      781 cgaactccgg attgcggatg gctgtgccgt gaagctctgt ctccatgctt ccatctccat
      841 agaccgtgta tacataggcc agcttaaagc cccagacctg attatagcag ccaaagtgct
      901 tctggatgta aacctgagcc ttattctgtc cgctgctgac agtcatgtac tccatctcct
      961 ccattcctct ggaaataaag tagttgttct tccagtcatt gaccttgtac atgtcgttgt
     1021 caatatcagc ccgatccacg gtaagcacag gacctctctt aacaagctcc tggccgccct
     1081 tcttcatgga agacagcacg ccgtgaacct tatcaaacga gtataccaca tcctggcagg
     1141 aaatggaaac ccctgtagct gtctctgaaa cagatactgg cagctcttcg cgtttcacgc
     1201 tgaccgtctt cttctcagac agcgggaact gataatgtcc cagctcatgg ccggccggag
     1261 cccaggcagt ctccttcttc tccctgacag agatatttaa atagtaatct ctgttgtcct
     1321 tccattccgc cgcactgtga ggaatcatga gaatctcctc cacgcccggc tctgtgtgca
     1381 gagaatcgat ggtaaaggtt tcaatcgtct cttttccgtc tgtcacagag cactccaggt
     1441 aaattccatc cagagtctta aaatcatagt aattcttaac ggcaaacaga tctcccgtct
     1501 ctcccaggcg ctccatccat accgggcaga tgacctgctt gtactctaca aggcctggag
     1561 acggagttct gtctggcata agaagtccgt cgatacagaa gtttccgttt gtagggaagt
     1621 ctccgtagtt gccgccatat ttataggtaa cggttccgtt ctcgtctgtc ttcttaatac
     1681 cgtggtcata ccactcccag ataaatccgc cctgaagacg gtcataggtg cggtaaagct
     1741 tctggtaatc tgccaggcat cccggtccat ttcccatggc gtggctgtac tcgcagtgga
     1801 tgtggggacg gttgtgcttc attttcgtct cgccaatctc ctttaagcct ttgagtctgg
     1861 agtacatggt agagtacacg tctgtgatct cagcctcgaa atccccctca tagtggatca
     1921 gacgggaact gtccatagcc cggacggcct cagcctcctt cttaaagttc acgccgaagc
     1981 aggactcgtt gcccagagac cacatgatga tggacgggtg gttgtaatct ctctccacca
     2041 tgcggaccgc tctgtccaca taagcgtttt cccaggacgg atcgtctgta atcatatcgt
     2101 aaacgtgagc ccactcaaag ccgtggcact ccagatccgc ctcgtcgatc acgtacattc
     2161 cgtactcgtc gcagaaatca tagatagcct caatagacgg atagtgggag aaacggatgg
     2221 cgttgatatt gtgctgcttc atcagaagca cgtcctgtct catcacttcc agatccaccg
     2281 ttctgccgcc ttccggagaa tagtcgtgat ggtttacgcc gttaatcagc acagccttgc
     2341 cgttgactgt aaatacgttt ccctttacct ccactcttct gaagcccagg cggtagctta
     2401 cctgatggga aacggccccg ttctgctcca tggataacgt aagggtatag aggtaaggcg
     2461 tctccgctgt ccatgtgcgg acagactcca gccgggcaga gatggatgcg ctctctcctg
     2521 cctcagcctc tccagacgct gctgtcactc cctcggcatc cgcaagaacc cactttaaga
     2581 ttccctctcc cgccagacgg atctgcgcgt caaacagtcc tgtcgtgtag gaatcgtcca
     2641 gatcggcgtg aatccggcag tccttgattc tggccttcgg cgcgctgatc agggatacgt
     2701 ttctgtagat tccgctgaac caccacatat cctgatcctc taagtaggtt ccgtcagacc
     2761 acttgtaaac gcggactgtc acctggttct ctcccttatt aatataggaa gaaatgtcaa
     2821 actctgccgg gaggcgggaa accttgctga agcccacgtg ctctccgttt acccacacgt
     2881 cataagcgct gtccactccc tcaaagcgga gaatggtgtc gttctccatc cagttctccg
     2941 ggatctcaaa gcttcttttg taaattccgg taggattttc tgtaggcaca tagggcggat
     3001 ttaaaggaaa cagatacagc acgtctgtgt agtgcatatg atcgtagccc tttaactgcc
     3061 agcaggacgg aacctcgatg gtatcccatc cggcggtgtc ataatcgcgc ttctcaaatc
     3121 cttccgggct gtactccggc gccgtcagat atttgaaagc ccagcttcca tttaaagaaa
     3181 cctgctctgc ggagttggtg aaaaaggacg tgcggcccgg cctgcggtta attcccgtta
     3241 aggtctgatc ctcccaccgt ttttttgctc tcatctgcat aacattcata cctcccgttt
     3301 ttacttgtat attctgctgg ttttctaaat taattatatc tattttttta gtaaaagtca
     3361 aatagtttac ttaatatttt tactgttctt tttactaaaa cctattgact ttttatatta
     3421 aaaggcttat tatttaatta cttttagtga ttttacccaa atcacggcgc cgtgttatcg
     3481 gcgtttccgc tggaaggtgg gtaaatagtt ccaattattt aggaggtaaa cgtatgaaga
     3541 aaacaaaatt gtttgtatct gcagcagcca tctctatggt cgcagccctt tccctcacag
     3601 gctgcggagg cggcggagac aagaacgcag cagagagcga caacactatc actgtatggg
     3661 cctgggacgt tgctttaaaa cagcttcagg cttctgctga gaaatttaag gagacacatc
     3721 ctgatgtaga gttccagttc gaggagatgg gtacagagca gatttataca aaacttgcca
     3781 ctactctgaa tacaggaaaa ggacttgcag acgttatcct tctggagggc gagcaggtaa
     3841 gcggctacgc ttctaagtat ccagacggtt ttgcagattt aagcgatatt gtaaataagg
     3901 acgactatct ccctgttaag atgggcgagg ttactgtaaa cgataaggtg gtaggcttcc
     3961 cgtgggatgc aggcccagtg gctctcttct accgcaccga ctactttgag caggccggag
     4021 taaacccgga agatatcaag acatgggacg acttcattga ggcaggaaag aaagtaacag
     4081 ctacctgcaa gactccttcc ggagagcctg ttaagatgct tcctatcgct ccgaacggat
     4141 ccaacttctg gaagctgctt ctgacagaga agggcgcagg ctacttcgac gcagagggca
     4201 acacagctgt taactctcct gaggctctcg agtgcatgga gatggccaag aagatctacg
     4261 acgcagacat cgcgttaaac tacacagact gggccgagta cgagggcgtt gtcgtaaacc
     4321 agagcgtcgc tactatccct gaggctgtat ggatgatcgg aaccatcaag gacaagggac
     4381 cggatcagtc cggcaagtgg ggcgttatga gccttcctgt attccctgga gacgagcctt
     4441 ccggttctac taacggcgga tccgatatcg taatcccggc tgcctccgct aatgtagata
     4501 ttgccaagga attcgtacag tttgccatga cagacgtaga tttacaggct gacggctttg
     4561 taaactatgg attattcccg tcctacatcc cggcttacga tgcagaggta ttcacagagc
     4621 cagacgagtt cttcggcgga cagaagattt acgagacctt catcgagctg ggcaagaagg
     4681 ttccggctgt caactacaca gagaactaca acgaggccat gaaagctgcc ggctctgcct
     4741 gcgctaaggt ttacctggaa ggccaggatc cgaagaccgt tctcgaggat cttgagaagg
     4801 atttagtttc taagttcgga aaataacctc tccatccaga acaacaggag gctgacatga
     4861 aaacacgtaa aaaagcaaag tttttccctt acggaatgat gatgcccacc atcgttatat
     4921 tcgggctctt tatgatttat ccggtggttt actccttcta tttaagcttt atggagttct
     4981 ctggaggaac ctatacgttt gtgggactgc agaactacat tgaacttttc aaggatcctg
     5041 tattctacaa ggctctgttc aatacgttct tctacctgat tatacaggtt ccggttatga
     5101 tcggccttgc gcttctgctc gctgtgctca tcgagcagaa gtttatccgg ggacggggat
     5161 ttttcagaat ggccacattc ctccccacta ttacatccct ggttgcctac gcgctggtgt
     5221 ttaaggtact gtttaatacc gatcacggct taatcaacta catcgttgag tttttcggcg
     5281 gcgagaagat tcagtgggta tactccgcat ggccggcaag ggcgtccatc attatctcca
     5341 ttacctggag atgggttggc tacaacatga ttatcatcct ggcaggcatt caggcaatcc
     5401 ctaccgagat gtacgaatct gcttctctgg acggagcgaa cttctggcag cagctcagat
     5461 acattacgat tccagccatc aagccgattc ttctgtttac aaccattact tctaccatcg
     5521 gtacgcttca gctcttcgac gagccgtaca tcctgactca gggcggaccg aactatgcaa
     5581 ctattactct gggagaatat ctctatgata acggcttcaa gttcctgaaa ttcggctttg
     5641 cttccgcttt gggatacgtg atggttatta tcatcggaat attatcctac attcagttca
     5701 gaatgaataa ggaggattga catgcttaaa aaaatcggag tatacgcatt tttaatactg
     5761 gcggctttcc tctccttatt cccattctac ttcatgtttg tcagcggaac aaacacgaat
     5821 gcggaaatcc tggccgcccc gccgaaactg ctgccgggct ccatgctttc ccacaacttt
     5881 tccattctcg tggaaaagat ggatattttc agggttgctt tcaacacgct gtttatctct
     5941 gtcgtgttca cagtgctggc cctgatgctc tattccgctg ccggatacgt gcttgccaag
     6001 tttgatttca agggaaaagg cctgattttc agctttatca tggtttccat gatgatcccg
     6061 ccacaggtta tgtacgttcc gttattccag ctgtttgtag ccacaggtat gacaaatacc
     6121 tacacagctg ttattctgcc cgctctggcc aatgccttcg gtattttcct gatgcgccag
     6181 aatatgatga acttccccac tgcccttgtg gaggcggcca gaatcgacgg atacagcgag
     6241 ttcggcatct tctgccggat tgtgcttcct aatgtaaagc cagccttaag cgccctggtt
     6301 atctacatgt tcaccagtat gtggaacaac ttcatgtggc cgttaatcgt cctggagaca
     6361 aaggatatgt acaacttccc ggttgccctg gctgttctgg acggaaatcc gaccaacaag
     6421 gactttgcag tgattcttct ggctaccgct atcgctactc ttccgatttt gattatcttc
     6481 atggtattcc agaagcagtt cgtagcaggc gttatgggag gcgctgtcaa agagtaaatc
     6541 tttcagaaac tttcaaaaga gatgtgtatt ttctaaatta agacaagccc ccgggcggcc
     6601 ggttcatcca taccggctgc ctgagggctt gctttattat tacttttcca ttttcattct
     6661 ctattaaagc tcaaactctt ccagaatgcc tgccaccagt ccgatgcagc cttccacgtc
     6721 tctctcgtct gccacctcag ccggagaatg catatagcga agcggaatcg ataccagaat
     6781 gacaggagtg cctccgttct cgaagtgaat cttgtctgcg tctgtgcagg tcaggcggct
     6841 ggctgtctcg tactgaaccg gaataccccg tctggcggca attttctccg cctggcggtt
     6901 cagctgagac ggaatcagcg ggctgttgca gagcacagga ccagctccca gctttacctc
     6961 tcccgcttcc ttcacagagt acccgtaagg ataatcggta cagtaggtca cgtccactac
     7021 cacagccaaa tccggcttta cagttccagc cgtaaagtac gcgccgtttt tcgtagtctc
     7081 ctctcccgct gtagccgcgc agtagactcc ccgcttcgtt ccggcctcct tcactctctt
     7141 aaaggcctcc ataatgatat agacgcccag gcggtcgtcc agggcccttc ctgcaaatct
     7201 gcctccggaa agcttctcaa aaccgcagtc aaaggtaacg gtggagcctg gctttacaag
     7261 gcttaacgcc tcctccttgg aatcggctcc gatatcaatc accagatccg ttacctccat
     7321 cttctctttt ctgcacaaag ctctggagcc gtttacaacg cccttcacca tgccgtgctc
     7381 tgtatgaatc tgaaccttat ggccggggta agtctgggga atcactccgc ctctgtcaat
     7441 agcgtaaagg tatccatgct catccgcaca ggttatcaca agaccaatct cgtccaaatg
     7501 agccgtagcc agaattttcg gctctgcctg cggattcagc actgccaccg tatcgttcag
     7561 aatatctgtg aatacctggt ctgcaaaggg ctccatctcc tccttcacga tctggcttcc
     7621 ctgtgcaatc tcccccgaaa ctgtcacagc atccaaaagt ctgtttaaaa atacttcatg
     7681 ttccatgtag gtcctcctcc tgtctttcat cttaccttta gatcttatct ttcccagcct
     7741 tgaatgtcaa tagaatacgg cgctttatct tttcatccac tgctttttat ggtaaactgt
     7801 tcatagcaca gtgtacataa actgtttcca tttattttca cactaaagga ggaattatcc
     7861 atgacaccat ccaatgtgta tttcaccacc tttcggactt catttcgcga aaatctgctt
     7921 cagaagctgg aacgtctgat taaaaaagcc ggactctttg aacaggttga cttccagaac
     7981 aaatatgctg ccattaaaat ccatttcggc gagccgggaa acctggccta cctgcgcccc
     8041 aactattcaa aggtgctggc agatctgatt aaagaacacg gcggaaagcc ttttttaact
     8101 gactgcaaca ccctctatat aggaggccgc aaaaatgccc tggatcacct ggattccgcc
     8161 tacaccaacg gctacaatcc cttcactaca ggctgccata ttttaattgc cgacggttta
     8221 aagggaacag acgaagctct tgtgccggta gacggtgagt atgtgaagga agccaagatt
     8281 gggcaggcca ttatggacgc cgacattttt atctccctga accactttaa gggccacgaa
     8341 tctaccggtt tcggaggcgc gatcaaaaat atcggaatgg gctgcggctc ccgcgccgga
     8401 aaaatggaga tgcacaacgc taccagcccc tttattcttc aggacaagtg tatcggctgc
     8461 catgcctgcg agagaaactg tgcccacgga gccatctcct tccaggaaaa gaaggctttc
     8521 atcgacgaga acagatgtgt gggctgcggg cgctgcatcg gcgtctgtcc tgtggacgct
     8581 gtggcaaacc actgcgacga atccaacgat atcctgaaca agaaaatcgc agagtacact
     8641 ctggctgtgg tgaaggatcg tccccatttc cacatcagcc tcgtggtgga cgtatctcct
     8701 tactgcgact gccacgcaga aaacgacgtg cccatcgtcc ccaatgtagg catgttcgcc
     8761 tcctttgatc cggtggctct ggatatggcc tgcgctgacg cggtcaaccg ccagccggtg
     8821 atggcaggca gcgttttaag cgagagggaa cactgccacc acgatcactt tacagacgtt
     8881 cacccggaga ccaactggat ggttgctctg gagcacgctg aaaagctgag aatcggaact
     8941 agagaataca atctgattac catttaaaag cattgaaaaa gagcagacga tttcgcgctc
     9001 ccccagggcc gttgcaaatc ctctgctctt ttcatatacc ggaatcttcg tttatttctt
     9061 tttttctccc atcttcacct gcatccaggc cggctggtaa aacagttctc tggcgttccc
     9121 tgtgtatctt cttcaccaga ctccccatat ccagcctgag ccgctcgtca ggccggaaaa
     9181 aggctcgtcc agcagaagga tctccaccca gcctgcaaaa gcgtaaaaaa agatgccttc
     9241 caaagccagt aaacggcgga acgcatctct tttcgctgca tcctgcaaca tacttattct
     9301 tttaccttgt aagcttcttt tacagttctt aaaaaccgct tggcagactt tgagagctga
     9361 tagtttttat tataaaccac attgatatcg cggccggaac gcttgctggg aacgggaaat
     9421 gctaaaagcc ttccatcctc cacctcttcc ctgacagcca gattcgacaa aatggaaatt
     9481 ccaagcccct gaatcacaga tttcttgatg gtctcctggt ttccaatact ggccataata
     9541 ttcagctgct ggggcaggat ccccagctcg gcgagctggc gctccgcttc ctttctggtt
     9601 ccagagcctt cctctctcat cagcatcgct tcctggcaaa tccaggaaat atcgccggac
     9661 gttcggtcta tcgcctggta gcgtccgctg ttcggcgcaa taatcaccat ctcatccctg
     9721 taaaaaggaa tatatctgca gtgctttttt tccagaacgg ttcctgtaaa gccgatatct
     9781 gccttgtgct ctgacacctg ctccaccacc tgggcgctgt ccatctcccg aatccgcagc
     9841 tgctctcccg gatatttttc gttaaatttt gccagcagct ccggcagaag atactgagcc
     9901 ggtaccgtag acgcggcaat ggcaatacac tgcttttctt ctgtcttccg gtgtccgaac
     9961 tcctccttaa ttttgtactg aagatccgcc atctgtctgg cataaaaata caggcgctgc
    10021 ccctcttctg tcagacagac ttccttcgta tttctcacaa acagccggat atccagctcc
    10081 ttctccagcg ccagaatatg agcgctgact gtgggctgag tcagaaacag acgtttcgca
    10141 gctttagaga agctgcctga ctcggccacc tccacaaagg cctctaactg ttttaaattc
    10201 atccgtatgg tatcctttca actgtccccc tgatgtccat cccataacaa tacggattct
    10261 tctatttatt atttcaataa ccgaatcagc ttatcgctct caggcgccac gcttccaatt
    10321 acagagaccg ctgtatcaat accagaggct ttcagctcgg aaagaagcgt acctaagtcc
    10381 tccctggcca cgcttaacag aagaccgccg gaggtctgcg gatcgtacag cagatccaga
    10441 tagaattctt ctattccctg agcgtctacg cttccaatgg aataacctct gtttttgtag
    10501 gttccagccg gaacaaggcc cattttggca tattccacgg catcctggaa gtaagcgata
    10561 tcattgacct tcagctcaaa cgtaacgccg ctggccgaag ccatctctgc acagtgtccc
    10621 agaagtccaa aaccggtaat atctgtgcag gcagaaatac agcatcgatc cgcagccctc
    10681 tttgccttct ggttcaggga agccattacc gtctgcgcct cctgaacagc tgaggcagaa
    10741 gccagctcag ccttgatcgc tgtgttcaca atgccgcttc caatctgctt cgtcaacacc
    10801 agcacgtccc ctggcttaca gccgtaattc ttaaaaatct tctgaggatg tacaaatcca
    10861 gacacgcaga gaccgtattt cggctcgtcg tcctggacgg aatggccgcc gaccaggacg
    10921 gctcccgcct ccttcacctt atcggctccg cctgccagaa tgtctcccag aattcccgga
    10981 tccagacagt ttggaaatcc cacgatgttg agcgcaactg ccggctctcc gcccatggcc
    11041 cacacgtcgc tcagcgagtt ggccgctgca atctgcccaa acatatacgg atcgtccaca
    11101 atcggggtga aaaaatccac agtctgaatc atggcaattt catcagttat cttataaata
    11161 gccgcatcgt cggatgtctc aattccaact aacaggttat catcatgaaa tttcggcagc
    11221 ttgcccagaa cctgggcaag ggtctcagga cctattttag ccgctcatcc agatgtcttg
    11281 ctaagcgttg taagccttac gttctgcttc atagacaatc ccccctcctt cgcatctttc
    11341 tgtaaaataa ataaaaaaaa tcaaggggaa ggtctaagac gaaccccttg atttcatgtg
    11401 cattttaatt agtcctcaac cttgatgatc tctttcttgt tgtaagaacc gcaagccttg
    11461 caaactctat gaggcatcat taaagcgccg cacttgctgc actttactaa gtttggagca
    11521 ctcatcttcc agttagctct acggctgtct cttcttgctt tggaagattt attctttgga
    11581 cagatagaca tggttacacc tccttaaatt gtttgtagat atcctggata actgccatcc
    11641 gtggatcgag cgacgtccgg tcgcaggtac aagtcccata attgagattc gttccacatc
    11701 tattgcaaat ccccttacaa tcttctctgc aaaggacttt cataggcaaa ccaatcagaa
    11761 tttcatttaa cgccaactgg tctacatcca gattataacc gcttaaataa ggttgttcat
    11821 ccaaatcttc tgcctgcccg gcctctggtt tatccgtctc cagctccctg tcaagcgtga
    11881 gctcacagac ataggctacc ggttccagac atctggagca tggaatctcg acagtcacct
    11941 tcgtgctgcc ctccaggaaa tacttcctgt ctcctgtgtt tgtcactgtc agctgaaaag
    12001 gctctgcgga cacaactctg tagtcctctc cccctatgct gacctccgtc agtccgattt
    12061 ctgcgtcata aacctttttc ttgccttcgc aggtaaaaag ttcagataaa ttaatcagca
    12121 tattaatctc ctaatacgca ctatgctatt atacataggc cctcgttttt tgtcaatggt
    12181 taatttgcag attatcttac tgaacggatt attttactaa agccagagtc tctcttgcga
    12241 tggcaagctc ctcgtttgtc ggaacaacta agagtttaac cttggactct ggtgtggaaa
    12301 tgattctctc cacgcctctg cacttgttta actcctcgtc gatctctgct cccaggtaag
    12361 tgaggctctt gcataccttg cttctgcatg cagcgtcgtt ctcgccgata cctgctgtaa
    12421 atacgattgc gtcaacgccg ttcatagctg ctgcgtaagc gcctacgtac ttgattacgc
    12481 ggtaagcgaa gatatcgaga gctgcctgag ccttgtcgtc gcccttctct gcagcctgct
    12541 ccagatcacg gccgtcgctg gataagcagg agattcctaa cataccggac tttttattca
    12601 gaacgttcat catctcgtcc agtgtcttgc cctctttctt agcaacgaac tcgatgatag
    12661 ccggatcgat gtctccggaa cgtgttccca ttacaagtcc ctcaagagga gtgagaccca
    12721 tgctggtgtc aacggatttt ccgttcataa cagcggaaag gctggcgccg tttcctaaat
    12781 ggcatacgat aatcttgcag tcctcatacg gctttccgat gatctcggct gttctcttgg
    12841 aaacgaagct gtggcttgtt ccgtggaagc cgtatcttct taccttgtag ttctcgtagt
    12901 actcgtatgg aagaccgtaa aggtatgctg tcttcggcat tgtctgatgg aatgctgtat
    12961 caaatactgc taccatcggc acgttcggca tcagctcctg gcatgcgcgc acgccgatga
    13021 ggttggccgg attgtgaaga ggagccagat cgctgcactc ttcgattgcc ttgattgtct
    13081 ctgcagttaa aacagtggaa gctgtgaact tctcgccccc gtgtacgatg cggtggccta
    13141 cagctccaac ctcagataag ctcttgatta cgcctgtctt ctcatttgtc agggcctcaa
    13201 gtacgaactt gatagcctct gtgtgagtcg gcatagcctt ctcgctcttc tccttctctc
    13261 cgtcagccgg ctgataggta agaattccat cgattccgat tctctcgcag agtccctttg
    13321 ccagtacgtc ctctgtctca gagttaatca gctgatactt taaagaggag cttccacagt
    13381 taataactaa aatattcatg tctcctaacc ctttccttta tatacattct ttttattttt
    13441 gctttatgac atctgagcct gtacagctgt cagagcaact acacctacaa tatcctcagc
    13501 ggagcagcca cgggataaat cgttgaccgg tctggaaata ccctgaagca tcgggccgta
    13561 agcctctgcc ttagccagcc tctgaaccag cttgtagccg atatttccgc agtccaggtt
    13621 cgggaaaata agaacgtttg catggcctgc aaccgggctt cccttagctt tggatttagc
    13681 aacctcagga acgagcgctg cgtctaactg aagctctccg tccagatcaa gctgcggata
    13741 cttctcgtgt gcaatctcaa ctgcctttgt aaccttatca accagcgcat gctttgcact
    13801 tccctttgtg gagtgggaca gcatggcaat aatcggcttc tctcctatca gagcgcggaa
    13861 gctcttagca ctggaatcag cgatagcagc taactcctca gagttcggat cctgattcag
    13921 accacagtct gcgaataaga aagtgccgtt agaaccatac tcacagttcg gaacgtccat
    13981 aataaagaag ccggaaacaa gctctgttcc aggagcagtc tttaaaatct gaagagcagg
    14041 tcttaaagta tctgcagtcg catggcatgc tcctgcaacg agaccgtctg catccttctc
    14101 ttttaccatc ataacgccgt atgtgatata atctgtcttt aagagttcct cagccttctc
    14161 cttagtcatg cccttgtgct ttctcagctc aaacagagtc tctgcatagt ggtcaaactt
    14221 cggatctgta tctggatcga ctacttttaa tcctgttaaa tcaacttcca gccagccggc
    14281 accatccatg atcttctctt ccttgcctac catgatcaga tcagccgtgc cctcctgaag
    14341 aatctgagca gctgcaatca gtgttctttt atctttactc tcaggtaaaa cgattgtctg
    14401 cttgtcctgt tttgcctttg ctttcattaa atcaataaat gccatggtta aaaaacccct
    14461 ttcatagaga taaatgtatt ttctgctaac attatatacc acctgtttat tgtatacaag
    14521 agataattgt cgatttttta ttaaatattt ttttaacagg cttgtttctt ttttaacctg
    14581 tcgtttcatt cctcccttgc ccttttcgtt tcttctatat ataatgatga cagtccggcc
    14641 tctccgttca gagccttggc ctgcgcgtgc ccgggccgga atcattcagg aacttcagaa
    14701 aggcggaagc agctatgcat gtaacaggac tgatcacaga gtataatcca tttcacaacg
    14761 gccatttatt tcatttaaag aaggcaaggg aatcgacagg cgccgactat acggcagtgg
    14821 tgatgagcgg aagctttgtc cagagaggtg ctcccgctgt gttcgacaag tacagccgca
    14881 cccgggcggc tctccttagc ggagctgacc ttgtgtttga gatgcccgcc cccttctcca
    14941 ccgcctcagc cagagaattc gcctcctatg ctgtggcgct cttcaccgct ctgggagccg
    15001 tggactccat ctgttttggc agcgaatgcg gggaaattga accgattctg cgcgcggcac
    15061 gtctcttaaa tgaagaatca gaatcgttta aaaaacggct gcaggatttt ctgaaggaag
    15121 gaaaaacctt ccccgaggcc agaagctccg ccctggcaga agagggcgcg gaggaggcga
    15181 agcttctctc ctcccccaac aatattttag gggtggaata ctgccaggct gttctgcgcc
    15241 agcgcagtcc tctctcctgc tttacgatta aaagagaagg aaaaggctat cacgatcctt
    15301 ccctggacgg tgtgctggga tctgccctgg ctgtccgcca ggctctccag agcggaacgg
    15361 atgtccaggc tctgcgtttt ctccttcccg atccctcctt tgactccgtc tgccgcagta
    15421 ttcccgtctt cttagacgat ttttccgggc ttctgaatta ccgcctcctg actgagcagg
    15481 agccggaacg ctatgcggaa atacggcctg agctggcggc gagaatcaaa aagctggccc
    15541 cgggcttcgc ttcctttgac cagcggatca aggagctgaa aagccgccag ctcacctaca
    15601 caggcgtcag ccgcgggctg atccacctga tccttggaat tgagcaaagg cagatggatc
    15661 tctttaaaga ggcaggcttc gccccctacg ccagaattct gggctttcga aaaagcgcag
    15721 cccctcttct gcggcggatt aaggaaaatt cctccatccc agtcatcatc aaactggccg
    15781 gagccgaaaa aagactggat cccgcaggcg ccgccatgct ggcctgcgaa atccagtctt
    15841 cccatctcta tcagaacgtc cggtgtgaaa aagctgcctc aggagcgttc cccggcagaa
    15901 ccgccgtctt ccaaaacgag tacactcagc ctgttttaat cctggaccag gagacttccc
    15961 tgctccttta aaagccttaa aagtgccggc tctgcgtgaa gctcctctat cagctctgaa
    16021 agcccctgct gcttctgggg ctttccttgg cggactgccc ggatcagaat atttttcggc
    16081 gtgtgctcca tgtcgataaa ttccaggatc tgcgttctgt agcccgcctc ctccagaagg
    16141 ccggcccgga cagcgtctgt taaaagcgca gacattctct ccttaatcag cccatacttg
    16201 agggccggag ccagcaggct gctctcaatc tgcccgttca gctcgtgctg gcagcaggga
    16261 actgacagaa tcactttcgc tccccagcgg actgccttgg ccagagcata gtcggtggca
    16321 gtatcgcagg cgtggagagt caccaccatg tccacctgat cggccccctc ataatctgcg
    16381 atatccccgt gaaggaacgt cagattttca aatccaaact ttttggccag cctgctacag
    16441 agggcaatca catccttttt cagatccagg cctgtaattc ggacaggata tcccttcact
    16501 tcctttaaat aatagtacat ggcaaaggtc aggtaggatt ttccgcatcc gaagtctatg
    16561 atccttgtct ccttcgagcg gtccagccgg ggcaggatat cctccacaaa ttccaggaaa
    16621 cggttaatct gccggaattt atcatacttg gcctttacca ccgccccgtc cttcgtcata
    16681 acccccagat ccaccaggaa gggaacaggc gtcccttccg gcagcacgta atgcttcgcg
    16741 cggttgtggc ggctcagcct ggccagatcc tccgggctga tatccgccgc cttcgttctg
    16801 cctgtctgca ccgtcttttc cgccttctta tccggcgccg ctaaaacgac ctttttcttt
    16861 atcttaacag tcaccgttcc tttttttccc accagaatcg tcccgcttcc aagcagcgag
    16921 aaaatctcgc cgttccggta gagtttggaa agctgatctt tcaggtactc tgccgcctcc
    16981 ctggcactca tatttttatg gaaggcctgc ttctctgtaa attcttctgc ctgaaattta
    17041 agcctgccct ggagaatcag gggacggaga atcaatttaa catacccgtc cctggttctg
    17101 ggattgctta aaataatccg atccagcttc tcattgagaa aaaaagcgaa cgtctcatcc
    17161 agcttatgtc cctgttccat cttatctcac ctttgcctag ttcttgaagc tgtggacagg
    17221 agccgggatc cggcctgtac ggctgataaa atcctcgcac ttaaagcggt tcaccggcat
    17281 gacgggagcg tagcctaaca gaccgccgaa ttctaccgta tctccaatct gcttgccgat
    17341 caccgggatc aggcggaccg ccgtcgtctt ctggttgatc atgccaatgg cagcctcatc
    17401 tgcgatgatt ccggaaatcg tagccgcaga ggtatctccc ggtacggcaa tcatgtcaag
    17461 tcctacggag cagacgcagg tcatggcctc cagcttctca atggtcagag cgcccagcgt
    17521 caccgcgtcg atcatgccct gatcctcgct gactgggata aaggcgccgc ttaagccgcc
    17581 tacataggag gaggccatga ttccgccctt tttcacctga tcgtttaaca tggcaagagc
    17641 tgccgtcgtt ccaggcgcgc ccacccgctc cagtccaatc tcctccagaa tctcagccac
    17701 gctgtctccc actgccggag taggagccag agaaaggtcg ataattccaa agggcactcc
    17761 cagacgcttg gcagcttcct gggctaccag ctgtccgact cttgtgatct taaaggctgt
    17821 cttcttaatg gtctcgcaca gtacctcgaa attctccctt ctcaccttct ccagagccgt
    17881 cttcaccacg ccggggccgc tgactccgac attgatgata gcctccgcct ctgtgacgcc
    17941 gtggaaggct cccgccataa aggggttgtc gtccggcgcg ttgcagaata ctaccagctt
    18001 ggcgcagccc agggaatcct gatccttggt ggccttggct gtctccagca ccacctctcc
    18061 catcaggcgt accgcgtcca tgttcagtcc gcacttggtg gatcccacat tgacggagct
    18121 gcacacccgc tctgtggaag ccagagcctg cggaatggaa cggatcagaa gctcgtctgc
    18181 tcttgtcatg cccttggata ccagcgcgga atatccgccg ataaagttga cgcccacctc
    18241 tctggccgcc tggtcaagtg tcttcgcaat gctgacaaaa tctgcctctg ttttacaggc
    18301 gctgccgccc accagagcga taggagtaac ggaaattctc ttatttacaa tgggaacgcc
    18361 aaactcgcgt ccaattgcgt ctcctgtgga gaccagatct ctggcgtagg aggtgatttt
    18421 ccgatagatc ttttcattga gctcttccac agtggaggcc gcgcagtcta agaggctgat
    18481 tcccatggta atggtgcgca catccagttt ttcattgtcg atcatgttgt tggtctcatt
    18541 gacctccagc atgttaatca tcatcgtatt tctcatggtt ttgtgtcctc cttagatgcg
    18601 gtgcatgctg gtaaaaattt cttctcgctg gcagcggata gacgctccga ttctctgtcc
    18661 cagctcgtcc atttcccctg caatctcatc aaaagatttg ggggatctgg caatatccac
    18721 gatcatcatc atatcgaaaa tttccttcac aatcgtctgt gtgatatcca ggatattaat
    18781 attgctctct gccaggtagg tacagatgtt tgccgccatt cccacatcgt tttttccaat
    18841 tacgctgata ataattctgc tcataatctc tcttctcctt atttttatta tttcattctt
    18901 ttttactaaa ctgtcacaat ctccgagacg gcatcccgtc tggctactgt aatcgggaaa
    18961 tcgctggaat ggtagggcgt atcgctctct gctatctcca gcttcaccgt ctcgtaggcc
    19021 agctcctcat agttgttttc cttgctcaga tggcccagaa aaatgtgctt taagttatcg
    19081 tgaaggacac agcttaaaag ccttcccgca ttgtcgttgg acaggtggcc gtactccccc
    19141 agaattctct ttttcagata gtaagggtaa ggaccggcct ccagcatctt cacatcgtgg
    19201 tttgactcca gaagaatagc gtccagaccc tgaagcctat caatggtgta ctgggaataa
    19261 tttcccatgt ccgtggccac tgccaccgac tttttcccct cctgcacccg gtaggccacc
    19321 ggattggccg cgtcatggct gattttaaag ggcttgatct ccagatctcc gatgaaaaaa
    19381 tctacgtcgt gggccacagg gcgcaaaagc tcttccggat aatcgcctag gcttttcatg
    19441 gttttgatct cctccagggt ttccctggtg ctgtaaatag gcactccgtg ctttctggcc
    19501 agaaccccca gtcccttcac atgatctgag tgctcgtggg taatcagcac cccatccagc
    19561 tctgatccct tgatgcctat gtcatttaat ccctgttcga tcctcttatt gctgattccc
    19621 gcatccacca gcaggtgtgt gtgatcgctt cctatataga tacagtttcc gctgcttccg
    19681 ctggcaatgc tcaccattct catgcttgtg cttcctcttt cattttctca ttcagtatgc
    19741 gttctatctg ctgtcttacg tcttctatcg tccggttgtt gtcaatgatc cggtccgcca
    19801 tggcccggaa ctcttcttcc gacctctgat ttcccataat gtccatacat tttttccggc
    19861 tgtaaccgcg gctggccatc aggcggctga tccggttctc cttcgaggta tagacgtacc
    19921 acacttcgtc aaacatccgg ttgtgttcct catcaaacag ggcggcctcc actgccacca
    19981 gcttttccga tgcagtctgg atgccctcct caatccgtct ccagactgcc ggatggacga
    20041 tggaattcat ggtttcaagg gcgtccgcat ccttaaaaat cagctctgcc atcttctgtc
    20101 tgtccacact tttatccggc tttaaatagt ctgccccgaa ggcttcctca atcctgcggc
    20161 tggcctcgcc tcccggcgcc atgacctcat gggcaatatc gtcggccatg agaagctttg
    20221 cgccgaactc ttcctttaaa agtcttaaaa tctcgctctt cccggaaccc actcccccag
    20281 taattcctat tactctcatc ttatctctcc cgcctctgcc gctatttcgt ctcaaaccag
    20341 gaatttcccg tcttcatatc tgattccaga gaaaccttca gatccgccgc atgcttcatc
    20401 tcctctgaga gaaccgtcct gaccgtgtca agctcttctt tccatgtctc aattagaagc
    20461 tcatcgtgca cctgaaggac aatcctggac tttaagccct ctcttctcag tcttctgtct
    20521 acccggttca tggcgatttt aataatatct gccgccgttc cctggattgg agagttcatg
    20581 gccactctct ccccaaagga acgctgcatg aagtttttag aggacagctc tggaacgggg
    20641 cgtctgcgcc cgaacatggt agttacatag ccatgctcct ttccctcctc caccagacgg
    20701 tccagaaatt tctttacctc aggatacgtc tcgaaatacc ggttaatata ctctaacgct
    20761 tcctttctgg taatgcttaa atcctcgctc aggccaaagg cgctgatgcc gtagacgatt
    20821 ccaaagttga ctgccttggc gtttcgtctc tgcagaggcg tcacctgatc caaaggcaca
    20881 tggaatacct ccgaggcagt gatggcgtgg atatcctccg cttttttgta ggcctcaatc
    20941 aggcgctcgt ccccggacag atgggccagc actctcagct caatctggga atagtcggcg
    21001 tccacaaaga cgcagccctc ctggggcaca aagacccggc gtatctcccg tcccagctcc
    21061 atcctcacgg gaatattctg gaggttgggc tccgtactgc tcagccttcc tgtcgccgtt
    21121 accgtctgat tgaaaattcc gtggattctg ccgtctgccc ggatgtagcc ggccagtccg
    21181 tctgcatagg tggatttcag ctttgtcagc tggcggtagt ccagaatttt ctgcactacc
    21241 ggatactcgg gagccagctt ctccagcacg tccgcggcag tggaatatcc tgtcttcgtc
    21301 ttctttccgt agggaagctc catcttcccg aacagaatct cacccagctg cttgggagag
    21361 ttaatgttga aaacctcccc tgttccctga taaatttcct gctccagcgt ctcaatctgt
    21421 ccccggagcc gctcgccgta agcctgaagc tcctccctct ttacgcagat tcccgcctgc
    21481 tccatgtgga acagactgta aataagaggc atttcaatgg agaaaaacag ttcctccatg
    21541 ccagtctcct tcagcttctc tgtaagcctc tctctggact tccaggcagt ataggccatg
    21601 tagcagagac actgctcccc ggaatttaat tcttcttttc cgttctctga tgcctcctgt
    21661 cccagatcca tcgtaatttc cgagaagata tcgccaaagg actgtttacc tatcagatcg
    21721 cccttggacg ggacggtcat gtccagataa tctctggcca gatcgtcata atcgtaggta
    21781 tcctttaaag gattcagcag atatcctgcc actccggcgt caaacagctg cctgctgtct
    21841 ggcgtatcct ccccgcagtc tcccaggcgg tctgctgccg gcagaaacgg aagctggctt
    21901 ttcaaatcca gaaagctcag tcccgctcct ccctctgcca gacggttcag ctgctctgtc
    21961 agatattctc ctgaaatggt atctgaggta tgaatgcagt aaatatcctg ctctccaaag
    22021 gccagtccca gagccagaac ctctcccgcc tccacagcca gctggacgcc tgcctcgccg
    22081 ttctttctcg cgcgttcaaa caactgcgcc gcttcctcaa gattcgaaac ggcgcgaaac
    22141 tgtttttctt cctggttttc cgctctggaa tccgcatcga atctcagaag cagagactta
    22201 aattccagct ggcttagcag ctggtaagcc tccggtgtgt agagatttcc cattttcgcc
    22261 tcctccatgg aaaactcaat gggacagtcc gtgcagatta aggccagctc cttgctcatc
    22321 tgggccatgt cataatgctc tctcagggct ttctgtgctc tgggaggctt cacctcgtca
    22381 atgtgggcat aagcgttctc aatgctcccg taggctgtga tcagagccgt cgccgtcttc
    22441 tccccaatgc ttggaacacc gggaatgttg tcggaggcgt cgcccatcag agccttcaca
    22501 tccacaaatt ccttcggtgt cacctgatac tgttccttca cgtcggcagg atagtagtcc
    22561 ttaatctccg tgcctcctct ggtggttttg ggcatccgga tcttcacatg ttcgtccgcc
    22621 agctgcaaca gatcccgatc tcctgacacg atggccacct ccgctccagc cgccgcgcac
    22681 cggccggcga tggttcccag cacgtcgtcc gcctcatagc caggcagaga gcagatggga
    22741 attcccatag cggagagaac ctccttaatc acaggaacct gctcccgcag ctcctccggc
    22801 ataggctttc tcgtcccctt gtaggcttcg tacatcttat ggcggaacgt gggttccttc
    22861 aaatcaaagg ccactgccag gtgatccgcc ttttcatcct caatgacccg gaacataata
    22921 tttaaaaatc cgtaaacggc gttggtgtgg agccctttcg aattcgtcag ctccggcacg
    22981 ccgtaaaagg ccctgttcag aatactgtgt ccgtctatta aaactacctt gctcatctat
    23041 ctgtctccct gcacattttt actgtcaata gaaccaaatc cgaaactgca gaagggctgt
    23101 gacaatcact gccatcacgc ccagcgtgtt gactgcatag tgaaacatcc ggaacatcca
    23161 catatggctc acctttaaat aggattcctc aatcttgtgc tccaaatccc cggcaatgtc
    23221 gtaagttccc gaatcgtgat ccagctgcct gagtcccacg tccaccataa aataaatctc
    23281 cagctcctcc cggcagttgg ggcactcgtc aatatgattt aaaaaggcct ccagctcgtc
    23341 gccagccagc tcgtccctaa tatagggcgt caccagacgc tccgcttcct gacaggtcat
    23401 aggccccctc ctttcccatc tgcgcgcgta aaaatctttt cttatcatac aataagaaga
    23461 ggtgtttttc aagggaagct ttctctttca agaagaaagg atgctggaaa aaacgaaaaa
    23521 attcaaaaaa cagttgcaaa gtctcccgaa ttttggtaga ataaatttgt ttttaagctt
    23581 ctgaagcata gaagccggct tgtcggaatg gcagacgagg aggactcaaa atcctttggt
    23641 ggcgacaccg tgcgggttca agtcccgcag ccggcactcc ttggcagggg caggggatac
    23701 tgatttttgc acagcaaggg ttagtatccc tttttctttc tttttaacag gaatatgcct
    23761 tctcgcagac agacaggggc agatgcggct ttacctgatc cgcatctgcc cctgaaactt
    23821 ttaccagctg ttattaactt ttatcgtgag ctgtttttct cctgctgctc cccttcattt
    23881 ctagtgatgg aacagacgga ttcctgtaaa tgccatcacc ataccgtatt tgttgcaggt
    23941 ctcgattaca ttgtcatccc gcacagatcc tcctggctgg gcaatatact ttaccccgct
    24001 cttatgagct ctctcaatat tatctccaaa tgggaaaaag gcgtcggaac ccagagtcac
    24061 atcctgcatc tggttaagcc actctctctt ctcctccctg gaaaatacag gcggcttctc
    24121 tttaaaaatt ctctgccagg atccctctgc cagcacatcc atatgctcct caccaatata
    24181 gacgtcaatg gcgttgtctc tgtctgctct cttgattcca tccacaaatt tcagattcag
    24241 cacctgagga gcctgacgca ggaaccagtt gtctgccttc tgacctgcca gcctggtgca
    24301 gtggactctg gactgctggc ctgcaccgat tccaatggcc tgtccgttct ttacgtagca
    24361 gactgagttg gactgggtat attttaaggt gatcatggct actgccatat caatcttcgc
    24421 gctgtccgga agctccttat tctctgtcac aatattggta aacatatcct tattgatatc
    24481 cagctcattt ctgccctgct caaaggtaat tccgtatacc tgcttgcgct ccagcttctc
    24541 cggctgatag tcctggttaa tctcaatcac attgtagttt ccgttttttt tggattttaa
    24601 gatcgccaga gcttcctctg tatatccagg agcgataata ccatcagaaa cctctctctt
    24661 aatcagcttc gctgtgtcag catcgcacac gtctgacaag gcaataaaat cgccgaagga
    24721 ggacattctg tccgcgcccc tggctcttgc gtaagcgcac gcaattggag aaagctctcc
    24781 catatcgtcc acccagtaaa tttttctgag ggtttcgtcc atgggaagcc ctactgcggc
    24841 gcctgccgga gacacgtgtt taaaggaagt agctgccgga aggcctgtag ccttcttaag
    24901 ctcgcttacc agctgccatc cgttaaacgc atccaaaaag ttaatgtagc ctgggcggcc
    24961 gcttaatacc ttaatcggaa gctcgcttcc attttccata aaaatcctgg acggcttctg
    25021 gtttgggtta cagccatact ttaactctaa ttcgttcatg tgtcctgcct cttttctgtt
    25081 tttctctttc tgattatttc atgtttttat tgataatctt tgtctgcttt tctcctgtag
    25141 caatgtcaat gtaacgtaca aacagggata ccttattatc agggttcaag ctctcccaaa
    25201 gcatggctgc aaaagcttcc atatcatctg gaatatccac cagcttcggc tctccctcaa
    25261 agctcggaag cggatttcca tcgtgcatat aggtatgaat aaatcttccc tctccagcca
    25321 gaggcttttc ataggcatag gtgtatctta aacaggaatc aggacatccg ctgtcacttt
    25381 ttaagataga catggcaaag ttgtagctgc cgttttcaat atgcatgata ccggaaatcc
    25441 taggcgtata gttaggcgca tccggctcaa attctctgct tcttaaagac tgctcaaagg
    25501 tgagctgacg atccattccc tcataaatgg tatccgtctg atctccattg gttacaatag
    25561 ttttatttcc cagcaccctt actggagcat agataatcag gctgggatcc gtaagcttgg
    25621 acggatcaaa ggcctgcgtg cggattccgt ctccctcctc cacaaacaca cgatttctgc
    25681 tgttttcact tcttcccatg atgaaatagg cggccactgc cttcgtgccg tcggcgctcc
    25741 ttccaatgac aatgcctctt ccagggtacg cattgttctt cagttcctca gaaagcgaga
    25801 tcttattcac cttttcgtcc tccctatacg gttattcaat ccgttcatca tttttatatt
    25861 ctgcggcatc agagtaccga acgtacactg gcgctgattt cattatatac catccctctt
    25921 ctgattgcca gtaataaaaa ctgaagtgtt tttagaagct atacttataa aaagttaaga
    25981 aatattaata taaaatttct gacattttac aggaagatat tgtataatgg gcttattaca
    26041 tgaattcatt gcataggagg aactaccatg cgtagaaaaa cactgttcct tgcagccctt
    26101 ctgctcgcta tggcagtaac cggctgccgg aagaaggaaa ccatcgattt atccacgctc
    26161 cacaccacag ctgccgagac ggaaaaccag tcagagaagg aaccttccaa ggaacccatc
    26221 cagctggata cggagcatac agagtcttcc tcagaaacag aacataaata ttctgtggat
    26281 atttccatgg aaacctacac agacggcggc gtttccattc agtaccctgt cctctccagt
    26341 ctgtcggatc aggagctgca ggaaaagatc aatcagctga ttaaagagaa tgccgtttct
    26401 gctgccaggg caaaggggct tcctgcagag ggcgcttccc tcactgtgtc tgcttctgtg
    26461 gaatcttcca acctgaagcg tcttgtgctg tcctataaag gggaattgaa aaagggcgct
    26521 gacaccgaac ggattttcta ctccaatacc attgatctgg aggagggaag gaatctgcag
    26581 ctgtccgact atgcggatgc ctacacagtc gccggctatc tggcgtcagg ggactatgtg
    26641 tttgcagagg ctcccaaagg agacgagact gctgtccggg cgtatataaa cggcgcggga
    26701 cgggatactg attattacta taagaagctg gcagaagccg atttttctga aacaggcgct
    26761 ttcccggagt actgtagctt tgaacgccag ggtacaatct ttgtgtctgt gcctgtcagc
    26821 cacgagctgg gagattacgc cctcatcaaa tatgttccgg ataacaaata gagaaaaata
    26881 aaggagattt catccatgga aaacgtaacg attttcactc acccgctgat tcagcacaaa
    26941 atttctatct taagaaagaa ggagaccgga accaatgaat tccgctccct gatcgaggag
    27001 atcgccatgc ttatgggcta tgaagccctg cgggatctgc ctctggagga ggtggaggta
    27061 gaaaccccca tcgagacctg catgaccccg ttcttagccg gcaaaaaact ggctgttgtc
    27121 ccgattctca gggctggtct tggtatggta aatggtattc tggctctcgt tccctccgcc
    27181 aaggtaggcc atatcggcct ctaccgcgac gaggtgactc acgagcccca cgagtactac
    27241 tgcaagctcc caagccctat cgaccagaga atcatcgtgg taaccgatcc catgctggct
    27301 accggcggtt ctgctgtgga ggcggtagac tttatcaagc agcacggagg caagagcatt
    27361 aaatttatgg ctatcatcgc cgctccggag ggactgaaaa ggcttcacga agcccaccca
    27421 gacatccaga tttatgtggg acatgtagat cgctgcttaa atgaaaacgc ctacatctgc
    27481 cctggtctgg gcgatgcagg cgaccggatt ttcggaacga aataggaagc tcaggcctgg
    27541 aagggcggtt tttaccgctc ttcctttttt tctgccacct ctcccagtct cttgtagatg
    27601 gatttttcac tgacgcagcc tctcacgctg gacagagggt agatattgga ttcccgtcca
    27661 atgaccgttc caggattcag cacagagccg cagcccacct ccacctggtc tcccagcatg
    27721 gcgcctacct tctttcttcc ggtctcaatc tctccgtcct ctccgtggat tttgactaac
    27781 agtttatcgg atttgacgtt ggaggtaatg gagcctgctc ccatgtggga cttatatccc
    27841 aaaatagagt ctcccacata attgtagtgg ggaacctgaa ccttatcgaa gagaatgacg
    27901 ttcttaagct ctgtggaatt gcccactacg gcgccctctc ctaccagagc gcttccgcgg
    27961 acaaaggcgc agtggcggat ctccgctccc ctgcacacaa tcagaggacc gtttaaaaag
    28021 gcagtgggag ccaccttggc ttccttatga atccagatat tctctcccct cttctcaaac
    28081 tcctcttcag gaagagtatt cccaagctct gtcagaaagg cgctgattcc ttccagagct
    28141 tcccatggat actcaaagcc tgacaaatat tcgcctgcca tggtatgagt caggtcgtag
    28201 agcttctcaa ttttcatatc ctgttttttc attatttttt ctctcctttt ccagcagagg
    28261 cagccttttt tgtactgcct gttttataat tttgggcggc cagctcaaac tggcggcgca
    28321 gtcccgcctg attggccatg tggacggccg cgtaggttct gcctgccaca aaccgttcca
    28381 gcttttccat gtactctgcc tctgtgatgc ttccctctgc cacataggtc agcccctttt
    28441 cccagctggc tgtcagctca ggattcaaaa gctggcggat agaagcctgc accacctcat
    28501 agatcagctc gcccagaagc gtaggcgtaa taacctgtgt tttggcattc agggacagat
    28561 agtgaatgct catcagcttt ttcaaaatct ccgccctggt ggcgctggtt ccgattccgc
    28621 tgcccttgat ctgggctctc agctcctcgt cctcaatcag ctgtcccgca ttttccatgg
    28681 ccagaatcat ggaaccggaa gtgtaccgct taggcgggga ggtctccccc tccttcacag
    28741 aaagcgattt aagctccaga accgttccct tcttcaggcc ttctaacatc tgtgcaaagg
    28801 ctccgtttcc aatgaccgtc tcctgagagc cttctttttc ccagctctcc gcgtccgatt
    28861 ctgctgcctg cggctgcttt tcctttccgg cttcctccgc cccgtcgttt ttcccagcgc
    28921 gggagacgtc ggacaccttc aggtatcccg gctccttcag cagcttaaag ctggcgaaga
    28981 aatgctctgt ctgtgagagc agctccaccg aatactttct gtagactgca gccggataaa
    29041 aaatgctcag gaagcgtctg acaatccttt catacacttt agcgttcagc agcgagaggg
    29101 atcttaaagc tcccattccc tgtccggtgg gcacgatggc gtagtgatcg gtaatctgct
    29161 tatcatttac atatctggtt tttccaatgg ttttccacgt tccccctgcc aggacttcct
    29221 ccgcaaaggc ggcgcagggc tggaatcctc tcaagccgga aatattcttt gcaatctcct
    29281 tcgccacagc agaggacagc accctggcgt ctgttctcgg gtaggttacc agctttttct
    29341 catacagctc ctgcactact ttaagagtct gatccgggct gatcttaaac agctttgagc
    29401 agtcgttctg aagctccgcc aggttgtaga gaagaggcgg atttttcgtc tccttcttct
    29461 tttccactga gagtaccgtt cctgacatgg gcggcttctc tgacagaaaa cggatcagct
    29521 cctccgcctt ctctctctcc ttaaagccat tatcccggta gagcgcaggg gactggaaat
    29581 accttgagcc ttctgcggcc ttccactccg cctggaaatc cattccgtcc tgctgaaagg
    29641 ttccaatgac ccggtaaaag ggggtcttca caaagcttcg aatctcccgc tctctcctga
    29701 ctgccattcc aagcacgcag gtcatcacac ggcctaccga taccaccgtc cacttgcttc
    29761 ccataaaatt tgcaatggcg gggccgtatt tcagtgtcag ggccctggaa aaattgatgc
    29821 ccataagata gtcctctttg gctctcaaat aagcggaggc agccagatta tcgtactcgc
    29881 tcaggctttt cgcttccctg attccacgca gaatctcctc ctctgtctgg gaatcaatcc
    29941 agactctctt ttcctgcttt ccctttacac ccgccatctg ggctaccaga cggtaaatgt
    30001 actctccctc ccgtccggag tcggtgcaca cataaacggt gtcgatatcg cttcgtttca
    30061 aaagcgagct cacaatttta tactgtttct ttacgccgtc aatcacctga tatttaaaat
    30121 ccttcgggag aaacggaagc gtatccagac gccacttttt atacctggcg tcatactcct
    30181 ccgggtagct catggtcacc aggtgtccga cacaccaggt caccaccgct gtctcggact
    30241 caatatagcc gtcagcccgg cgcccggaaa ttttcagagc gcgggcaaac tcctgggcga
    30301 cgcttggttt ctccgcaata tataaagctt tggccattct gttccccctt cctagcttcc
    30361 tgccctgtat tcagaaatca ctgcagccgc aaacatgaga acgcagcctg ccagcatttt
    30421 ggctgtaact gtctccttca ggaaaatcac ggaaaaaatc aggccgaata cagattcaaa
    30481 ggacagcagg atcgacgcgg tattcggact caaatacttc tgccccacat tctgcactaa
    30541 aaagcccagc atactggcaa tcagccccag atacaaaagc ggccatgcag tctgccagtc
    30601 caaaagctct ctaacatccc ttactccctc tgtggcaagg gccaaaaccc agaacagaag
    30661 cgcagaaacc ataatctgga gtaccgttaa aagcaccgga tctctgtgcc tcgtataccg
    30721 gtccacatag accatatgcc aggccagaaa tacgctgcag aggaaggtca gcacgtctcc
    30781 cagattaatc ccatgttctc cgttcaggga gataaatgcc aggccgatca ccgccaggac
    30841 tgcagctgtc agattattct tcctgggctt cactccgttc agcacccagt gcagaaacgg
    30901 tacaataatt acatagagtg tcgtaataaa ggcatttttg ctggctgtcg tatgctgcag
    30961 tccataagtc tggaatacat agctcattcc cagcagaacg cccagcacaa tcccgcagtg
    31021 caggtcccgg cggttcatat gaatcaggcg tctgtgaaac agaacggcca gccccaggga
    31081 agcaatcgta aaccggtatg ccagcacata ggcaggactc agcatatcaa tggagttttt
    31141 cattaccacg aaagtgcttc cccatatgat agtaactgcc agaaaggccg caatcgccag
    31201 ggctttcgcc attcccatat gtttcgtatc cataatctct tttcccttct tcggcacaaa
    31261 gcgaaatatt tcctctccgg gccgaagcaa aaaaacgaca gggagtccgt ctgttcctct
    31321 ggactccccc tgtttttcat ctattctgta caaaaacggt aaaccgtctt cgtctgtttc
    31381 tcaacgcccg cttttataac gggagatgga aactgcggat ggttcactgc gtctggataa
    31441 tactgcgtct caaaacagta tgcgcggcgc gctccgtaga ccgctccatc cttgcctgga
    31501 aggctgttgt ccaggtaatt ggccgtgtag aactgcacgc ctggcatatc ggtccagacc
    31561 tccatcacgc ggccgctttc cttatcccag gccttcgcag ccagagccag accttctctg
    31621 tcccggttaa ttacccagtt gtgatcatag ccgtttccct tcaccagctg gtcatagccg
    31681 ctctccagat cctgcctgat ttcctttgcc tctgtgaaat ccatgggagt gcccttcacc
    31741 ggcacaacgg ttccatatgg aatagaaacc tcgtctgcag gagtgaactg atctgcgttc
    31801 agatacacct gctgtcccat agcgtctccc gactgatggc ctgccaggtt aaaataggcg
    31861 tggttcgtca tattcatgat cgtgtccgca tctgacacgc cttgatagcg gatgtgaagc
    31921 tcgtcctgat cattcagcgt ataggtaacg gaaatcttta aattcccagg gaatccctga
    31981 tctccgtccg gactttccag agtaaagcag acagagcttt cgtctgcctc ctcccaggtt
    32041 ctggcctccc agagacggtt tctgtagaaa tcattgccgc tgtggagatt gttcggccca
    32101 ttgttgacag tcagagcgta ctctctgccg ttcagctcaa aacggccgcc tccaatccgg
    32161 ttggcgttcc gcccaataat ctcccctaag tgagcgtcgc tggccagata gtgttccggg
    32221 ctgtcgtagc ccagaaccac gtcggcgaac ttcccctctc tgtcaggaac cagcatggaa
    32281 tgccacacag ctcccagatc gagaaatccg gctgtcagtc cgtttttatt ttctaatgta
    32341 tatttatgca cagcttctcc gcccggcatc tgtccgaacg cttcctttgt atacggcata
    32401 gctgctcctt tcgcctgtct gctttttact gctccttcgc ctgaatatat ccctgggctg
    32461 tcagaagctc cgcgcagaga acggctcctc ctgccgcgcc tcttaacgta ttgtgggaga
    32521 gaccgacaaa cttataatcg taaacggtgt cttctctcag gcgtcctacg gaaacgccca
    32581 tgccgcgctc gaaatctaca tccagcttta cctgagggcg gttgtcctcc tccagatact
    32641 ggataaactg cttcggcgcg ctgggaagct caagctcctg tggaagtccc ttaaatgcag
    32701 tcagcttctc aatcagctgt tccttggaag gcttctttct gaattttaca aatactgccg
    32761 ccgtatggcc gtccagcacg ggaacgcgga tgcactggca ggtaatgacc ggctcgctgg
    32821 ccttcacaat cacgccgtcc ttaatttctc cccagatacg cagcggttcc tgctcgctct
    32881 tttcctcctc gccgccaata tacgggataa tgttctctac catctccggc cagtccttaa
    32941 aggtttttcc ggcgcctgaa atagcctggt aggtagtcgc cactacctcg taaggctcaa
    33001 attccttcca tgcgctgagc accggagcgt agctctgaat ggagcagttg ggctttacgg
    33061 cgataaatcc tctctttgtt cccagacgtt tcttctggaa ctctatcacc ttaaaatgct
    33121 ccggattcac ctccgggatt accatcggca catccggcgt ccatctgtgg gcgctgttat
    33181 tagatacaac cggcgtctct gttctggcat aagcctcctc aatggcgcgg atttcgtcct
    33241 ttgtcatatc gactgcgctg aacacaaaat caacgcctgc cgcaaccttc tccacctcat
    33301 tgacgttcat gacaacaagg ctttttacgc actccggcat gggagttttc atcttccagc
    33361 gtcctcccac agcctcctca tatgtttttc cggcagatct ggggcttgca gccactgtca
    33421 cgacctcata ccatggatgc tctgccagca gggaaataaa tctctgccca accattcctg
    33481 ttgcgcccag aacgcctacc tttaatttct tcttcatctc cataaccgtt ttctcctcat
    33541 tcccggaaca aatccgcttg tatttcgcct tctgtctgct ctgcggccgg aacgcgatct
    33601 gatacttcac tatcctacaa cagattgcat aaaaaatcaa gcttctggaa aaatcggaat
    33661 cagttttctc tccgccacag ataccaggcc taaatctgac atcttcacct ccggaatgac
    33721 aggaagagcc agagtcacga ttctaagcag cggattctcc atatccgtca gtcccagctt
    33781 ccgttccacc tctttcatgg cggaagcctt tctggaaagc tcctccgcct ccaaatttgt
    33841 catcaggcca gccacctcca gcggaagcgt gtgaagcacc gttttatcct ttaccgccgt
    33901 catgccgcct ccgcagcgga tcagttcttc tgccgctgcc agaccatcct ccggattaaa
    33961 ataaaccact gtcaggttgt gggagtcatg ggataccgta gacgccacag ctccctctct
    34021 caggccaaag tttttcacca agcccacggc cctggttccc tttccatgcc ggttaatcac
    34081 agctacaaag gcctcgtttt cctgtaatac cagctgtccg tccctgattt cgtgctcctg
    34141 gactgtgcag attgtgtggc tctgaattct tgttttgtac tccatcacat tcactgcagc
    34201 cgtgccatgg tttttcggac atttcagaca gaaatcctcc aaagagagtt cgcccacgtt
    34261 catggaattc ctgttctcca gctcaaatgg tctctcctca atctctgcaa taagccttcc
    34321 gtcttctgcc gccagctgtc cttcaaagaa aactgctttc gcccacatgg tccgcaggtc
    34381 gtccgtcagc accatatctg ctatatatcc cggcgctatg gctcccagat gttccattcc
    34441 aatttcccgc gctgtgttaa tggtagcgct cttaatggca agaaccgggc ccatgccgct
    34501 ctccaccgct tttctcacta ccgcgttgag atggcctgtg tgaagcagat catcgctttc
    34561 tctgtcgtcg ctgcagagcg tcagggtatc aaaaaaccgg atatccttca ctccgttcca
    34621 gattgcctcc acatttttag tgatggagct ctctctggca tccacgtaca taccgcttct
    34681 cagcttcttt aacgcctcgt ctcctgccgt agtctcatgg caggtggcag gtcctccaat
    34741 cagatacgct gacagctttc tgcctgtcac agccggcgca tgtccctgaa gatacaggcc
    34801 ctttttcccg gccgcctcaa tgatctccat catccgatcc tcgccgtaca tgacgccgta
    34861 gaagtccata acctcagcca gtcccactgc ccttggaagc tcagccagcg cctcaatatc
    34921 ttcagccata aacgctgcgc ctgcattctc gcagcccgga accgccggca cacagcttgg
    34981 tatatctacc agctggcgca tgggaagccc ctccgccgca tcgtgcatgt agacgacgcc
    35041 ctcccggccg tacacattgg caatctcatg gggatcgtgg ataatcgtcg tggttccatg
    35101 ggggatcacc gccttggcaa aatttctggg tgtcatcata gagctttcaa tatgcatgtg
    35161 ggaatcaatc agccctggta tcagatatct tccctgtccg tcatagaccg tttccgcgtc
    35221 ataaggcccc tccaggcagg aatcctccac atgggcaata aatccgtcct ttacatagac
    35281 aaccgccgga taaatctctc cggtaaacac attgaccaga cggcagttca ccaccgccag
    35341 atcagccttc tccaggccaa gggcagtccg aagcagcgct tttttatttt taggctccaa
    35401 tgtcatcata taaactctcc ttctctccgg tatgaaacag ctgcagatat gaaatggctg
    35461 ttcttaaata aaagcttgtg taagtaaggc aaaaggctgc tgcaaaagaa ttccttccct
    35521 tgcagcagcc tttctatcag ccggatcagg cctgcctgtt actgaacaat cgcgtcgatt
    35581 tcctcagcgg aaagtccggc tgcctctgtt acctcgatct ctccaacctg aatcttctcc
    35641 agagcttcct gtaccttatc cacgttttcc tggccaatgc tgtttgtcag gttgtcgtta
    35701 aatacgattc ccacagaatc ttctgccagt ccgtatgtta cgttctctcc gaacggtacg
    35761 ctggacggat cttctgcata gctctggcag atattgaaca gagcgttgtc cagtctctta
    35821 aggctggatg tgataacagc aggctgaagg ttgcttccct caagagcctg atactgatcg
    35881 ctgtccacgc cgattgccat tacgccgtct ttctctgcag cagcctcgat aacgccattt
    35941 cctgcgcctc ctgctacctg gaagataata tcagcaccct cggaaatctg ggcattggcc
    36001 agatcttttg cctttgcagt atccatataa tctcctacat atgctgtaag aaccttgatt
    36061 tccggatcca catattttgc tccctctgca tatccaacca gaaagttgtt tactgtagtg
    36121 ctctcaacgc cgccgacaaa tccaatagtc ttatctgcat ttgctgcatt ctctcctgta
    36181 gtatagtaag cagccactgc gcccgccagg aagccagact ggttagagtc aaacagaacg
    36241 cccattgtat taggtaaatc attactttca aaatccagtt cctggtcgaa caggataaac
    36301 tttgtatccg gatattccgt tggaattgtt tcaaagtttt ctttgttctg gaaacctgtt
    36361 cccactacaa tatcagctcc agcgtcagct gcatcataga aagccgcctg ccactttgta
    36421 gtgtcatctc ccatttccac tacgtttact tcatatttgt ctcccatctc ttcctgaatt
    36481 ctgagacttc cttcataggc agactgctgg aaggacaggt catttttacg gccaatgcag
    36541 agagtcagtt tgattttctc gccattctcc cctgctgcct gagcttctcc tgtctccttg
    36601 gatgctccgt ctccgcttcc tccgcaggct gtcagagatg ctgccatagc ggctgtcaat
    36661 gtcactgccg ctgccttttt cagtaatttt ctcataattt cctccttttt ctctaaaacg
    36721 tcttataaat cgtttattta tcatcagacc tgcttcccgc aggccagatt ttctgttgcc
    36781 tacagtccgc cctctgattt ctgacgcact ttatagtaga ggctgaacgc cacatagaaa
    36841 atgataatgg acgcataggg aataatcgtg atcaggtatg gatccacgtt gttattctgc
    36901 agataaatag atataccgct tccaactcca tagagaatag aactgactgt tcccatcaga
    36961 gcattacccg cagccatagc gttggttgcc aaggcaatat atccccggcc ggctaccata
    37021 ttcgatgtaa agcgatttac atagcccatg gaaaggtaca tacctcccag agacgctaaa
    37081 attccgctga taaacatagc ctggtagcgc accttttcca cattaattcc cacagaacgg
    37141 gccgcctctg ccgactctcc cactgcccgg atacgaattc caaaagccgt tttcttcagc
    37201 ataacaaaca taactactgc gacaataaac gccaggtagg tcaggcagtt atgccccgac
    37261 agaatatctc ccaccactgg gatatcctga atcacaggaa tattaactgc cggaaaggcc
    37321 tgggaaggaa gggaattgct ggcgttctta tccccagtca gagagtacag gcagaacaca
    37381 gaaccacctg tagcggccag attcaaagca actccagtga ttacctgatt cgcttttaaa
    37441 tgctgaataa aataagccag cagcattgtg taaaccgtac cggccagcaa accggctgca
    37501 gctcccacaa acagacttcc tgtaaagccg cttcccaaaa cgccgcagag agccgctata
    37561 gtcatagttc cctctaatcc cagattcaga agccctgaac ggctggcaat cagagcagcc
    37621 attgtggcca gcagaactgg cgtcgtgcag cgaagaaccg taaaccagaa atcaaggttc
    37681 actaaaaatt ccattttctc tcctccttag tttacaccag cagtttccat cgcctgattc
    37741 tgcagcgctt ctttttcttc cttgcgcttc ttcatttgat acataaagcg ctctgacgca
    37801 atcagaagaa tgataattcc ctgaataatg gatacaatct ctgaatccac atcgcctcct
    37861 ctggacataa ccagcgctcc gattctgatg taggaaataa aaaatgccga tacaggaatc
    37921 ataagcggct tcgttccggc cagcagattg atcagaatac catcccatac ataagtctga
    37981 gctgtaatcc actggaaatg agtgtacatt ccaatcatct ccacacctcc gcccagtcct
    38041 gccagcatac cgccgatcag ctgggatcca atcacgattc ccccgatttt cagtcctgcg
    38101 tacttggcaa agctggggtt ggaacctgtg attttcagtt cacggccaaa tttagactta
    38161 tccataagaa tccacatgaa gacaactgcc gcaatcatga tgaagattcc ataatgggcg
    38221 tttgttccct taatcatttt tcccagattc gccgtcttct ggaacttcac tgagaaggaa
    38281 ccgttggcct cgtccaggaa aaaagcacgg atcagccaat atccgaaatt aaagaagata
    38341 tagttcatca tcagagaaat taccagctca ttcgctcctg tctttctttt aataatgaca
    38401 ggaatcacgc caatcagtcc tcctacagcc atagacgtca ggagaattac cagctggtga
    38461 actcctgcag gcataggaca tgcaatcgcc agaatcgccg ctatcactcc tgaaaagtaa
    38521 aaggagctgt ctgccaccat ggaaaacagg ccgcttttat gcatgacatt gatagcaagt
    38581 ccgcagaaaa ccagcggaac catcatttcc actgcattga aaaaattccg cttagtagaa
    38641 aagggcccca ggagaaaacg gttcagggct gtcatcggat catctgccac tgcaaaaata
    38701 atcgccgccg cgatgataag ggcgatcaga atagaggtgg ctactcgaat gacgctgtac
    38761 cagtcaatct ttttctttat gttcatctcc tacgcctcct gtaatttttc tgcgggatct
    38821 tccttcaggc ccagcatata caggcccagc tcttcttctg tcgccgcggg aacgtcgttt
    38881 atcactcccg ctacctttcc ctggtggaac acaataattc tgtcgctgag agctctcagc
    38941 tccgtcagat ccgcgctcac taaaatcagg gattttttct catcccgcat ttccagaatc
    39001 tttttatgaa tgaactccat agcgcctacg tccacgcctc tggtgggctg gttcagcaca
    39061 atgatctccg ctccggctgt aaactctctg gccacaatcg ccttctgaac gtttcctccg
    39121 gaaaggctct taatgctgat atccagattc atcgtcttaa ccgtaaaatc ttccacgcac
    39181 ttaccgcagt aggattcaat ctcctccggc ttcagaatac ttccctttcc agaaagacgc
    39241 ttcaggcttg tggcaatcag attatcccgc acgctcatct caggcgcaca gccgtttaag
    39301 tttcgatcct ccggaacatg ggcgattccc agctttctgt tgtccgtaat ggaaagcttc
    39361 gtcagatcct ttcccttgta gaagacagat ccgctttccg cctttctgtt tcctgtcagg
    39421 atctccatcg cctccttctg gccgtttccc tcgattccgg caatgcccag aacctccccg
    39481 gccttcaggg aaaagctgag attatccagc ttcttcgtgc cgaacttgtc cgtataattc
    39541 agattctcta ctttaagaat tttctcgccg aactcctgag acgtcttgtc gtactccagc
    39601 ttaacgtcgc ggcctaccat gaggcgggaa atctcttcca gagtaatatc tgccagatta
    39661 taggttccga tggaacgtcc atcctttaaa acggtcagtc tgtcgcagag gtacttcacc
    39721 tcgttgagct tatgggagat aaagataatg gtatatccct cttttttcag gtttaacagc
    39781 tgctcaaaca gctcctccgt ctcctgaggc gctaaaactg ccgtaggctc gtccagaata
    39841 atgatcttgg cgcctctgta catcgtcttc agaatttcca gcttctgttt cattccgatg
    39901 gaaatgtcgc gcacccgctt ctgtgcgtcc acatggagat tgtatttctg agaaatcgcc
    39961 tccgtctcct ccaccgcttt cttctgatcg agaaacagac ctttcttttt ctcaatcccc
    40021 agcaccagat tttccgccac agtcagggaa ggaaccagca tcatgtgctg atgcaccatt
    40081 ccaattccat gttcaatggc gtccttactg gagtgaaaat gtacttcttc tccgtggagg
    40141 aacactttgc cgctggtaat ctcctcgatt ccaaacagca ttttcatcag cgtggacttt
    40201 ccagctccat tttcacctac aagagcgtgg atttcgcctt tattgacgct gaaattaatg
    40261 ttgtagttgg ccagaacacc gcccgggtaa atttttgtca gatcctccac ccgcaaaatt
    40321 tcttccgcca tgttttctcc ctcttacctt ttctcggttt acgctaactc cagggcaact
    40381 tccatcatat tggtgaaagt cgtctgacgc tcctcggcag tcgttgcttc tcctgttacg
    40441 gcagaatcag aaattgttaa gatgcagaga gcgtttacgc cggctgcagc tgcgttgctg
    40501 tacagggctg ccgcctccat ctcaactgcc agaacgccca tcttatccca gccaagtcca
    40561 accggcggaa gctctgggtt gtagaacata tcggaactta aaatatttcc cacatggaaa
    40621 ttcattccct tatttctggc tgcctggact gccttctcca aaagctcaaa gctgcagatg
    40681 caggagtaat ctcccggcag tctgaactgc ttcacgtagt tggatgtggt gcaggctccc
    40741 attccgatta caagatctcg gatcttcaca ttctcctgca gcgctcctgc cgtacctacg
    40801 cggatcaggt tcttgcagcc gtaaaaatga atcagctcat aggaatagat tccgatagac
    40861 gggcatccca tgcctgtgcc catgacagac actctctttc ccttatagta tccggtatat
    40921 ccgaacatgt ttctgactcc gttaaactgc tttacatctg tcagaaaatt gtctgcaata
    40981 tattttgccc ggagcggatc tcccgggaga agaatagtct ccgcaatctc tcctgcctgt
    41041 gctccaatgt gaggggttgg cactctgttc tcttccattt gattttcctc ctgaaatata
    41101 atttattcta aaactgctgc ttcgcaaagc tgtatccctg ctctcttgca gttttattcc
    41161 atgtttttct cttccgaagg gcggcgtagc cattccttca tataaaaatt ctttttttct
    41221 gaaaaatcag gatttttcac ctgaagctcc ggatgcgtca ggatctcctc cactgcggct
    41281 gttacaattt taagagtatt gaaatatgcg ttttcttcat ttgaaattga aaattccgcg
    41341 ctgtgaatcc tgcctgaaat accggaaaaa ccgaactgga ccgatggaat cagatatccc
    41401 agatctccga tatctccgga agcgcctgaa actacctgtt ttacaatctg gtcttctctg
    41461 cacagggaaa gcatctgtct gtgaatcacg tccgaaatct cctctgactg gtgaagaggc
    41521 atatatcctg ccgtgcgctc cacctgagca gtcatgccca gcgccctggc gcagtgaagc
    41581 acacaatcgt caaatttctt ctccgcttcc agaagcgtct ccagtgtgtt ggcccggatg
    41641 taggtttcca gcacagcctc ctccggaatt acgttgacgc ttcccccgca ggaagtaagc
    41701 accggatgca gctgaaggcc tgcctcagcc ggaaactgat ccttcatata ggcaatggca
    41761 ttcatagcca gactggcggc gtgaagcgcg ttccgcccca gatgaggcgc cgcaccggag
    41821 tgggatgccc ttccatggaa cactgccttc ttgacagcaa agcctgccag agaggactgg
    41881 acatcgaaca tcagctctcc gctgtctcca ttcacatgca tggaaatcac acagtctaca
    41941 tcgtcgaata cgccgtttgc tatcatatcc tgctttccgg aaaaatactg gatttttcct
    42001 tccttctgca tggctctgcg gctgtcaaaa tcaataaatt cctcggccgg agccgcaata
    42061 aagctgacgc gcccgcctga tttctccgca atcccccgct cctttaaaag cttcatggca
    42121 taagccataa cagctgtctg aatgctgtgg ccgcaggagt gaaatgcaca gggctgatcc
    42181 tgaatcctga cttccagggc gtccatatcc gctaccaggg cgatatgata gccgtcccct
    42241 gttcccagcc ccgccttcag tcccgtcaca cttaagcctg tttccaccga aaattcttct
    42301 ttgattaaaa aagaagtgag aatcccgctt gatttcactt ccttaaatcc cagttccggg
    42361 caggcgaaaa gagcatggcc cagctctgcc agttcctgct tctgttcttc tgtcaataca
    42421 atactgcctg ctgttcctat cttcatactc tgtctcctgt ctgaaacgct ttttcttctg
    42481 aatctgccgg cggtttgcct gccggcagat catacctttc tatactatat aaatgtagca
    42541 tgaatacaaa acaatgtcaa tttaaagtca agggcgcggc ggcttaattc agccgggttc
    42601 tgcttccttt tccatccctg tggctgagct taagccggtt taaatgcacc tgtttttctt
    42661 tgtatacggc aatattgtct gtattctctc ccagcaggta cacggtctcc agctgctctt
    42721 ccttagacag tttaattcct ctgactccct tggcattttt cttctgaacg ggtatctcct
    42781 ccgcagcaaa ccggagaaag acgccatgat ccgtctggag aaccgcctct ctggctccgt
    42841 ccatcatctg aatatcagcc acctgatctc cgtccgccag ctttgtggcc gccaccattc
    42901 tgttatttgt ctcaaactct tctcccggca cctgcttgag catcgcgcct tttgtggcaa
    42961 acagtaaaat atggcctggc agagccgcag cgttggtcaa aaatacgatt tcttcttttg
    43021 tgccgtcata cttgcagaga ttgtcaatgg gagttccctt atccctgagt tttccaagag
    43081 gtatgtccgc caccttgacc tggtgaagtg cgcctgtatc ggtaaacaga cagatcttgt
    43141 ccgtattcag gcagcagacc acatgggaat gttcactgtc cactgtctcc tgatttcggt
    43201 cgtaggtaga gcgctccagt atgcggctgt agccgaaccg gtccatgaca aatactactt
    43261 ccctaacttc cactgcgctc tcgtcgtaga cagcctccct gccgtcctca attcctgtcc
    43321 gcctcgggct ggaaaattcc tctttaatag aattcaaatc ttccttgatc acctgatcca
    43381 tggcgtctct gctggacaga attttttcat attctctgat cttcctgaga gtctctttgt
    43441 gttccttttc taatgccagg atttccaggc caatcagctt atagaggcgc atttccagaa
    43501 tcgcagatgc ctgccgctct gtaaagcaca gcttttttgc ctcctcctca aagccgggaa
    43561 cacggaactg gatctttgaa atatctccct ccatcaggca cgctttggcg tcctttaaat
    43621 ttttagagcc ccggagaaca gcgatgatca aatcaatgat atcgcaggcc tttatcagtc
    43681 cctcctgtat ctcctttttt tcctgctcct tctgaagcag cacctggtat tttctcgtat
    43741 tattttcata ctggaagtcc agataattct ttaaaatccc cctcagattc agcgtctcag
    43801 gcctgccctt cacaatggca agcatattga ctccgtaggt atcctccagt tttgtctttt
    43861 tataaagaat attcttaatt ttttcaatat ccgcatcttt tctgagttcc agcacaatac
    43921 ggattccttc tttattggac tggttggaaa tatccaccac atccgtcagt tttttagact
    43981 ctaccaggtc ggcgatatcc atgaggcact tattaattcc tgcgccaatc atggtataag
    44041 ggatctctgt aattaccagc ttgtccttat ctgccttcct ctttcccagc tctacctcca
    44101 tcctagcccg gagcttaatt tttccagttc cagtctcgta gatagcaggc agatccttct
    44161 tgttggcgat gatgcctcct gtgggaaaat ccggcccatg aagatattcc agaagcgaag
    44221 ccgtatccat ctcctgatta tcaatgtaag cctgaaccgt gtcaattacc tctcctaaat
    44281 tgtgcggcgg aatgcttgtg ctcattccta cggcgattcc ctccgcgcca ttaatcagga
    44341 gattgggaac gcggaccgga agaacctccg gctctttctc tgtctcgtca tagttgggaa
    44401 caaagttaac tgtcttatcc agatccttta agtaaacttc ctcggcaaac ttctccaggc
    44461 gggcctccgt ataacgcatg gcagccgctc cgtcgccctc gatggatccg aagtttccat
    44521 gtccgtccac cagaggcatt cccttcttaa acatctggga aagaaccacc agcgtctcat
    44581 aaatggagct gtctccgtga ggatgatatt tacccatggt atctcctacg atacgggccg
    44641 attttctgtg aggtttatcg tgccccagat gcagctcgct catatcgtag agcacgcgcc
    44701 tctgcactgg tttcagaccg tcccttgcat cgggaatcgc ccgggaggtg attacgctca
    44761 tggaataatt catgtaactg cgctgcattt cctccgaata ctctgttttt ataattttct
    44821 ctgacatccg tctattttcc tctcactact tttccttcaa tattgcaaag ccgtttttga
    44881 acgccagctg tccggctagg tgtcgatctc cgcctcgtct gcatggtcat agataaactt
    44941 ccgtctcggc ggcacgtcgc ttcccatcag catctctgta atctcggaag ccatcctggc
    45001 gtcctcaatt tccacctgct ttaacacccg gttctctgga ttcagcgtag tttcccagag
    45061 ctgttcggca tccatctctc ccagtccctt atatctctgc agagtaaagc ttcccgtgtg
    45121 gttctttctg taccgctcca gcgctttctc atcatacaaa tactgctcct ctcccttttt
    45181 gggaatcacc ttaaacaggg gcggcatggc aatgtacaca tggccctctg taattaagtc
    45241 gggcataaat cggtaaagga aggtcagaag aagcgtatca atatggcttc cgtccacatc
    45301 cgcatctgtc atcagaataa ttttatggta tctgagcttc gtaatatcaa aatcattgcc
    45361 atagccctca gaaaagccgc atccaaaggc attgatcatg gtcttaatct ccgcgttagc
    45421 cagaaccttg tccatggaag ctttctccac gttcaaaatc tttcccctga taggaagaat
    45481 cgcctgatac tgccggtttc ttcccatctt ggccgagccg ccggctgaat ctccctcaac
    45541 aataaaaatc tcacactttt cggcatccct gctctcgcag ttggccagct ttccattact
    45601 gtcaaaggaa aaacgcgact ttgtgagcat atttgtcttc gccttctcct ccgccctgcg
    45661 gatctttgcg gatttttccg cacagctgat gacagccttt aacgtttcga tattcctgtc
    45721 aaaaaagcgc tgaagctcat ctcccgccag agtaaatacc gcttttgtgg cgtctgcgct
    45781 ggccagtttc gttttcgtct gtccctcaaa aatcggatcc gggtgcttta cggcgatcac
    45841 tgccgtcatg ccgtttctcg tgtcggctcc tgtaaaattc gcgtcctttt cctttaagat
    45901 acccagttct ctggcgtagc tgttaatcag catggtaaat ttcgtcttaa acccagccag
    45961 atgggttcct ccctcctgcg taaaaatatt attgcaaaag cccagaatat tttcctcaaa
    46021 cgtatctacg aactggatcg ccgcctccac ctcaattccg tctaccgttc ccttcatata
    46081 aatcggatcg tggagggctg tcttcccagc attaatctcc ttcacatagg caacgatccc
    46141 ctccggttca gagtatgtaa tctgctcctc ctcgccggag cgcttatttt cataatggat
    46201 tgtcagcgcc ggatttaagt aggccgtctc atgcagtctg ctcttcagcc actccgcctt
    46261 aaactttgtc ttctcaaaaa tcgtatcgtc aggaagaaaa ttaatgctgg ttcccgtctc
    46321 cttcgtcttt ccaatgacag gaagaaggcc gtccaccaac tccactacag gaaggccccg
    46381 cctgtatgcg tcatgatgaa tctgcccgtt cttataaatc ctgatatcca ggcgctctga
    46441 cagggcgttc accacagagg agccgacgcc gtgaaggcct ccgctggtct tataggccgc
    46501 attgtcaaac ttgccgcctg cgtggagagt cgacagcact acccgctctg ccgacacgcc
    46561 ctttttatgc atttccacag gaataccgcg gccgttgtct ctgactgtac aggaaccgtc
    46621 cgattccaga gtcacccaaa tcgaggtgca ggctcccgcc agatgctcat ctacagaatt
    46681 atctacaatc tcataaatca ggtgattcag tcctttggtt ccaacgcctc caatatacat
    46741 gccggggcgc ttgcgcactg cttccagccc ttccagtacg gtaatactgt ccgcgtcata
    46801 ctgtgactta cccataatgt tcctccatct ctctatccgg cagtattcct gccgctgtct
    46861 gacatacaca gctcttttgc tctgtacttt tttattttca tttttcatct cccaggcccg
    46921 ccggatctgg gcaatagttt tcattatggc acaaaaccat aattatttca agaatattat
    46981 agcataatcg aacatatgtt ttcaatcact tttttctttc tgctgccgga aaaacagccg
    47041 attatagcgg cagctttctg attccggctt aaaacggaga gccagctcat tccattgctc
    47101 cgcctgttcc gtctccccca tcctgtaact gcagacagcc agctgaagcg ccggaatgta
    47161 gccgccgcag tccgggcata taaatccgcc ttttctctcg tctgtttttg cttttaaagc
    47221 cgtctcatac cagaaggagg cagttcgata ttcttcccgt ttaaaaaacc agtctcctat
    47281 atcgcagcac agctctgcgc gggggcagtc ataaaaaaat gaatggagca gagaggccag
    47341 cgccccctcc tcatcccctt ctgcctggcg gcacagggcc aggaaacgac aggcctctat
    47401 tttattttcc gcccatccgt ccgggcggga gagaaattct gtcagaactg cctgagactc
    47461 cctgaaacat tctgtgcttt ccatggccga atagtagagt tctcttccat aataaaacaa
    47521 atctctggca gtaaatggaa ccttctcctc tttcatcttt ctgtagatgc tcaaattccg
    47581 cctctggcct tcttttccct tctctgtttt cctgtgctca atttcaatat ctgtgtataa
    47641 aatctttccg gataaagcga ctgcttcatg gacttttccc tgccagcaaa atccctcgtg
    47701 attttttata aggcgctctc tataataaga aagggagggg ctgcctgtct tgtcaaaccc
    47761 catactatat ttcatcatga caatggcagt atcatcatcc agctcctcct tcagcctctg
    47821 tattttttcc tgctcaggct cagaaacaat atcatctgca tccagccaca tgcagtaatc
    47881 catttctgca tggcgaaacg cctcgtttct ggcagctgaa aaatcatcgt tccaggtgaa
    47941 atcataaact ttttttgtat atgtctctgc tattttcttt gtggaatccg aggatcccgt
    48001 atctacaata atgatctcat ccgcaaagct tacagcgctg tccaggcatc ttttcagcac
    48061 cttctcctca tcttttacaa tcatacatag gcttattgtt atcatagagt ctccggcagc
    48121 tttccattac tgatatgtat gtgtccggtt tttaaatcat gccgttccag cataaaatgg
    48181 atttttgagg aatttttcca tttttttaat ttttttgaaa tttatgcttg cattctcccg
    48241 gaacttatgg tatgataatc agcgtcgtca ggaaacgaca acatcgaggc gtggctcagt
    48301 ttggtagagc gctgcgttcg ggacgcagag gtcgcgtgtt cgaatcacgt cgcctcgatt
    48361 ccggcctgtt ggtcaagcgg tcaagacgac gccctctcac ggcgtaaacc cgggttcgat
    48421 tcccggacag gtcactggct tctgcagata tgcagaagcc ttttttcatt tcacagccga
    48481 tttattttat ttgttccaca tttccagatt gaatcgcagc tatattcctg gcgattctct
    48541 cccttggcca gtcccaccac ttgagttcaa gcagtgtatc aatggtttcc tcattaaatc
    48601 gttttcatat cggttttgca ggaacacctc ccgcgattgt ataaggcgga acatcctttg
    48661 tcacaactga ccgcgctccg ataacagctc cgtcgccaat cgtaacaccc gctaaaacga
    48721 ctgcttcata gccaatccag acatcgtttc cgacaacaat atccccttta ttatcccatg
    48781 cctttgcaac ctcttttacg tctaatcccc actcttcaaa gaaaatagga aacgggtagg
    48841 ttgacaggga cgatagcgta tgatttgcac tgttaaatat aaactttgcc ccacaggcga
    48901 tggagcagaa ttttccaatg agcagtttat cacaattgac aggatactga tacaaaacat
    48961 tattcttttc aaaatttttt ggttcgcccg caaagtcatt atatatggta taatcaccca
    49021 ctataatatt gggattagtg ataacacttt taagatatac ggtttcttta tcgtttgaac
    49081 gcggataaat tttctgtgac atagcagctc ctttcttacc tttctaatgg aaacgcgaat
    49141 gtttgaatcc attcaaaatg gttattttct gtgtaatata ccgtctgttc ttt
//
LOCUS       DBMDUW010000013        48251 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_679_length_48251_cov_4.446231, whole genome shotgun sequence.
ACCESSION   DBMDUW010000013 DBMDUW010000000
VERSION     DBMDUW010000013.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 48251)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 48251)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48251
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_679_length_48251_cov_4.446231"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(391..990)
                     /locus_tag="ACZPCR_04315"
     CDS             complement(391..990)
                     /locus_tag="ACZPCR_04315"
                     /inference="COORDINATES: protein motif:HMM:TIGR04076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04076 family protein"
                     /protein_id="HIR1230128.1"
                     /translation="MISIWRNPYLINKRSGLRMRHCVVCFCAFVLYIVCENKNAYDIM
                     RTEKLKFNELNTVKTQKVFMNYECKITVLETKVFPELQEKYLADPKSGPCPCFKAGET
                     FLLKRTPEQDDFYNLMNGKFCGEAWDAISRYVYAALQGGSIMRKWTNDDRMMIACCND
                     GTRPVIFKIERIDIPESEEEKQWLEKQNFKNTADDAYTG"
     gene            complement(1053..2354)
                     /gene="spoIVB"
                     /locus_tag="ACZPCR_04320"
     CDS             complement(1053..2354)
                     /gene="spoIVB"
                     /locus_tag="ACZPCR_04320"
                     /EC_number="3.4.21.116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIVB peptidase"
                     /protein_id="HIR1230129.1"
                     /translation="MTRKEKLQRLLTAVFWGSLVFTLGFTWFYLNEAIPDRLNLVVDE
                     AESFHFPLPVKVTLESDNSEVVVGNDSNIPAEQLHLQINHPFSLYSASEGIYRLDLKL
                     FGLIHFKDIEVNVSDTKYALPCGMPVGIYMKSDGLMVIGTGPVKTKDGSSFDPAQGLL
                     QSGDYIEAINGEPARKKEDMIEAVAKAQDSPVQLTVRRGEKQMDVTMTPLETENGDYK
                     LGVWIRDDTQGIGTMTYVTESGEYGALGHGISDSDTGLLVDTCGGELYDTEIMGIEKG
                     SMGKPGVLSGVIYYGSQSKLGTIDANTEQGIFGTAGNKMWKEIGTMFGTGPGREPVPI
                     GYRQDVRKGTAYIRSCISGKPEDYEIEIQKVDYSTSHKNKSLVIKVTDPRLLELTGGI
                     VQGMSGSPIIQDGKLVGAVTHVFIQDSTRGYGIFIENMLEH"
     gene            2709..3305
                     /locus_tag="ACZPCR_04325"
     CDS             2709..3305
                     /locus_tag="ACZPCR_04325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019163262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25"
                     /protein_id="HIR1230130.1"
                     /translation="MNTLKAEKRSMDVKAKRLRREGFVTGNVFGREIKGSIPVKISKN
                     EAERLLKTNGKGSQVLLNVDGTEMDVLIKEIDYNSLKGQVDEIDFQALVSGEKVHSVA
                     EIHLLNHEKVTTGVLQQMLKEVSYRALPSALVEKIELDVGGMRVGDTIRVRDLAIASD
                     KDVQLQTDLDTVVVEVYASKNTVADEDAEDGGSEAEGK"
     gene            complement(3705..4247)
                     /locus_tag="ACZPCR_04330"
     CDS             complement(3705..4247)
                     /locus_tag="ACZPCR_04330"
                     /EC_number="1.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003021715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HIR1230131.1"
                     /translation="MKKFVCTVCGYVYEGEAAPEKCPVCNAPASKFQEQAADMAWAAE
                     HVVGVAQGASEDIMEDLRANYEGECKEVGMYLAMARVAHREGYPEIGLYWEKAAYEEA
                     EHAAKFAELLGEVLTDSTKKNLEMRVEAENGATAGKFDLAKRAKAANLDAIHDTVHEM
                     ARDEARHGKAFQGLLERYFG"
     gene            complement(4442..4837)
                     /locus_tag="ACZPCR_04335"
     CDS             complement(4442..4837)
                     /locus_tag="ACZPCR_04335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002605221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HIR1230132.1"
                     /translation="MKTLKYSRQRESIKACLMGRKDHPTADALYTSIREQFPNISLGT
                     VYRNLNLLVELGEIRKLSCGDGTDHFDYDTSPHYHYVCKKCGKIVDLAMETDTGLEAA
                     ARECQKGTVEEHTVFFYGTCCDCLQEESH"
     gene            5046..9896
                     /locus_tag="ACZPCR_04340"
     CDS             5046..9896
                     /locus_tag="ACZPCR_04340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004515 - nicotinate-nucleotide
                     adenylyltransferase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009435 - NAD+ biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nicotinamide nucleotide
                     adenylyltransferase"
                     /protein_id="HIR1230133.1"
                     /translation="MSKKQVRQMIEELTAKLCAREFLAASNLSRESVLMLMNREYWEG
                     QLGRIFPIKRRIQCREIYEICREPMSLIGREPRDGWMKFTYQYVCHILYPDEEFSRQA
                     EPYAAGALFYLAVLQFIFDKEREVLPFEPMVDFAFLSEEEALSYESYTEYKKFKNAFY
                     KEYIYEMMRLNAEVTPFRTLEHIAGVHYVAMTVARGLYEAGVPIDLTLTSGAAAGHDL
                     GKFGCKPNERVPYLHYYYTNQWFNRHRMEYTGHIAANHSTWDLEPENLSVESLVLIYA
                     DFRVKQSRGEDGREITYISSLDEAFEIILSKLDNVDEAKLNRYRFVYARLHDFETYMR
                     SLGVDVNLDKKPVKTPPMPDISLRNTEQIVDSLIFMGVEHNIDVMHRMGAERQFGNLL
                     EAARSEKNWKNVRAYLNIFQEYFPYTNDIQKEQTLYFLYELLMHKEGDIRTQAARLIG
                     NVIAQFNAGYRKERPADMPDIADQKAMELWKTFLSMIICPDHKLTVQHKRRIGYNLKQ
                     VLSSMVEHAASADIEGFLQEFLRWYEAPEKRESGEAFVLLDALHNMPFERCSRENMER
                     MAEFACYYAVPRENSFEGLIIAAWRAFKLITAEVRDEPFCETIAEIVEHEAIAEDDIS
                     RTFLQYRILSNLGRNVSRQEEALYGRDVVSDIFLDNLKMATPWVLKAVNIKLLVDQVD
                     HGKKEHILHIAAHLSNLIKVSEYVVVRHDAGRALLRLAPLLTADQRNEIVVELLKGLE
                     VGEYEFSKYIPEYLGQLALWLPPEQLEEVLTYLRGLMANANDRVVSVALDTVGVLTEY
                     YPRYKERFAEDEETARERLGRLLGMVLGGLANHRETVRQEALLVTGQYMFGSRRLNDH
                     EKMEIFALTHKKLLFLINENKGGELTAFYRAAALSNICRFITAYRLTIGQMEIEERKK
                     VAFFPGTFDPFTLSHKGIVREIRDLGYEVYLAVDEFSWSKKTQPHLIRRQIVNMSVAD
                     EFHVNLFPDDIPVNIANPSDLKRLKEVFAGRTVYVVVGSDVIANASSYRKPPEKNSIH
                     SMNHIAFRRVGDRRSDNKYNREMMSLITGELIELELPEYLEDISSTKIRENIDLNRDI
                     SNLIDPVVQEYIYFNGLYLREPEYKPILRARAIGFEEKEKLSEEDEAAALEYIFSDEA
                     DGRGLLKRLQESDGTFLLLRNTVEDNRLTGLLKMRSVMPEELFKVLGSVSMADMVRRH
                     TLGSILLITGIYAEPDSAIYDPEQLLLTEALAKALEQHCSYAMFLPEEEPGEASQGAV
                     IRQGFAEAENFEGKRRLWLVDMHAPLVLVQNLETTLKEPFSSSPRILRAIHKAHRELQ
                     AAMTRLYPGQLVLSLSASVIYHRLVDKITQINQVPGEPTTPRVLGNDMCVPFGKILRG
                     KVVPNTVTKTIHTDKVYEPDLDSYRIEAFPYYSPLRSQVRTIKSFGRPVILVDDLLHK
                     GGRFDALEPYLREEGVEVKKVLLGMISGYGRDAMATRGFEADSIYSIPNLKFWFVEST
                     LYPFIGGDTVRRDTMKVAGLMPSVNIVLPYMVPPLKGCSEESLFELSACCVRNSRDIL
                     LALESEYRALFGRNLTLSRLSEAVILPLCPDKGDCINYDPNLAASVYLDNDLEMLHRI
                     SQLKNL"
     gene            9952..11229
                     /locus_tag="ACZPCR_04345"
     CDS             9952..11229
                     /locus_tag="ACZPCR_04345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005950756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HIR1230134.1"
                     /translation="MFYYRINGTLCCSLNGELDFPREELYGRGTDEKEAREKASGEEE
                     LVFLFERSPKNCRASFRVTDPALLYQDREDVSWLNKNVLGEGMRDEIVDSFIKEGKMR
                     AVNLNHPRFQEILKEKPEKKKKRVHVLAIGDVGSTLLTGLHLLGGDVISSIGICDISD
                     KVTARWEFEENQIAYPWDYDALPEVDVVKPEELFQCDVFVFVASKGIPPVGSEVKDVR
                     MYQFENNSKIVAQYARQAREEKFKGLFAVVSDPVDPLAKAAYLASNTDKNGVFDQKGL
                     RPEQIQGYGLGVMNARAAYYAKRDERFKQFLTEGRSFGPHGQDLVVADSIEHYNDELS
                     KELTQLTVTANLHMRAIGFKPFIAPAYSSGAISLILTLRGEWHCGSVFLGGIFMGVKN
                     RYTVHGLETEILPLPDALYERIVTAQENLKAVN"
     gene            11262..12395
                     /locus_tag="ACZPCR_04350"
     CDS             11262..12395
                     /locus_tag="ACZPCR_04350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HIR1230135.1"
                     /translation="MEQEERETETEKTDGEILLIRPREPGGRENSRLLKALREGLAGV
                     RLQEVTEVSQLEAMTDESGRLAPEGWTGKHLALFAIDLGEYGVNLEYTRLLGWLRSHP
                     KSLEGWTGGVTADADSDLYTKSAARELVFTANRAGCAFVGRPLVEGTKTLSNFAIVAS
                     NLGTDLYGAYVESIKLLVKEMAKSQKPDKERKRELLVLHASSHKSSNTYAVWQGVKQY
                     LTDISITEIGLRNGTLADCSGCPYKMCLHFGERGSCFYGGVMVENVYPAVKKADGILL
                     LAPNYNDALSANLTAFINRLTALFRTTRFYDKKLFGIVVSGYSGSDLIAEQMIAALNM
                     NKTFYLPGHFAMLETANHPGEAMKLPGIEERMRQYAKRIQNNL"
     gene            12513..13793
                     /locus_tag="ACZPCR_04355"
     CDS             12513..13793
                     /locus_tag="ACZPCR_04355"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1230136.1"
                     /translation="MSIRQWKRTLAIGGVIALTSQLYWNAFIDYFRISTSVILLPVLL
                     MTVGLELHTLTTCFVTSVIVFTVRFLIQSGSAGMTWQTALYVLPGALFYLSYGVIFKL
                     CIRNRRATTRKKLLWTIFLSDFGANLIEAEMQEYLQFRTLDEHIIIYLAVIAAIRTMF
                     ACMLLVGERQYRALLKKNEHERRYQRLFLMKTGLKNEIYFMRKNSEEIESVMANAYKL
                     YEKLCEQKLPDEMKQMSLAIARDVHEIKKDYFRIIQGIEEEIGSEYEEESMSFQDILQ
                     ILQSSTYHMIAAKGLDIKLVFSCNDNFITRGHYTLMAVLKNLVNNAIEAIESGKKPGQ
                     VRILEKKENGVYIFQVEDNGPGISERHLPNIFEMGYSTKFDYKTGNIYRGVGLWGVRN
                     TVEEQFKGTINVVSQPGKGTRFQVEIPAERLEES"
     gene            13795..14649
                     /locus_tag="ACZPCR_04360"
     CDS             13795..14649
                     /locus_tag="ACZPCR_04360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009532524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding domain-containing protein"
                     /protein_id="HIR1230137.1"
                     /translation="MEIYIVEDDRTVINILEDIIETNGLGTVCGTSGGQPADMEEIVR
                     LNPDVVLVDFLMPEKDGIQLVRELKEAGCGSRFIMISQVSAKELIGKAYSAGIDFFIS
                     KPINIIEVKSVIENVERQIQNERTLSNIRKMLLAEMKEEVPEEKKKNDGYVKKLQVIL
                     NRIGMSGEKGCDDIIKICQYLHANHKPISQVSIGQLCEILSAAPKNMEQRVRRAIAVG
                     MANLAHMGIEDFMNETFTAYSGTLFPFEEIRAEMDHIRGKRKYGGKVSIKKFIDSLML
                     AADRESRF"
     gene            14797..15981
                     /gene="gltS"
                     /locus_tag="ACZPCR_04365"
     CDS             14797..15981
                     /gene="gltS"
                     /locus_tag="ACZPCR_04365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015501 - glutamate:sodium symporter
                     activity [Evidence IEA];
                     GO_process: GO:0015813 - L-glutamate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HIR1230138.1"
                     /translation="MAPILELDMYQATAVAALVLLLGRFLVKKIPILDRYCIPAPVVG
                     GFVYAIVHCIVRSAGIIEISADMTLKNVFMVGFFCSVGFTASFRMLKKGGIQTIVFLG
                     LALAMVVLQNILGAGLATAFGLDPRLGLATGSIPMVGGHGTAGSFGPLLEDLGVANAN
                     VVAIASATFGLVAGCAIGGPIATGKIKKFKLHSTEMSAEGGFETEDAGKIDSKRFLDA
                     VLALIIAIGFGTIVSMLLGKLMTFPFYIGAMLVGAVIRNVADVAKKELPMEEIGVVGG
                     FCLSVFLGLAMIDMKLWQLAELALPLVVMLAAQTVLMFLYANFVVFNVLGRNYDAAVM
                     TTGFCGFGMGATPNAMANMQAVVGQYGPAPTAFMVVPLVGSLFIDFLNATILTGFINF
                     LG"
     gene            16320..17672
                     /gene="gdhA"
                     /locus_tag="ACZPCR_04370"
     CDS             16320..17672
                     /gene="gdhA"
                     /locus_tag="ACZPCR_04370"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015555083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HIR1230139.1"
                     /translation="MSKYVDRVLAELKEKNAHEAEFLQTAEEVLSTLGPVVDAHPEYE
                     KAALLERMVEPERTIEFRVPWVDDNGAVHVNRGYRVQFNGAIGPYKGGLRFAPSVNLS
                     IMKFLGFEQTFKNSLTTLPMGGAKGGSDFDPNGKSDAEVMRFCQSFMTELYRHIGPDV
                     DIPAGDLGVGAREIGYLYGQYRKIRGAFENGTITGKGMSFGGSLVRPEATGYGAVYYT
                     EAVMKHENDTIEGKSVVVSGFGNVAWGICKKLAELGAKAVTLSGPDGYIYDPEGVVTE
                     EKINYMLEMRASGRNKVQDYADKFGVQFFPGEKPFGVKADIVMPAATQNDVRMEEAKK
                     MVANGLKYYIEVANMPTTNEALKFLMEQPNMVVAPSKAVNAGGVLVSGLEMSQNSERY
                     SWTAEEVDTKLHQIMTGIHDGSAAAAEKYGLGYNLVAGANIVGFQKVADAMMAQGICW
                     "
     gene            17835..18779
                     /locus_tag="ACZPCR_04375"
     CDS             17835..18779
                     /locus_tag="ACZPCR_04375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HIR1230140.1"
                     /translation="MKCLIIDKVYAGIAEELGKYMEVKTADNLPSSKDQVLAEIGDVD
                     VLIMRVDPKIDKDIIDAAKNLKIIGVCSVGLNHIDMDYAKEKGIQIFNAPGLNANAVA
                     ELTISKMLDISRGTMTANTDVKVKHEWDKYKFVGRELRGKTLGVMGFGRIGRRVGELG
                     RAFGMTVVAYDPFLKAEDFEKEHATGMSIDELLKAADFVSIHVPLTPETKDLFNAKSI
                     AEMKDDAVVLNMSRGGIVNEKDMYEALKAGKIGGYATDVMENELAGSGLTGNDTFASP
                     LFECDNFIVSPHIGAQSVDASKDIGIHITAKVKEALGL"
     gene            19314..25868
                     /locus_tag="ACZPCR_04380"
     CDS             19314..25868
                     /locus_tag="ACZPCR_04380"
                     /inference="COORDINATES: protein motif:HMM:NF014850.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding domain-containing protein"
                     /protein_id="HIR1230141.1"
                     /translation="MKKKTKRVVPALLSLVMAVSSVPGPAYGAPLVTLFSSAEDDTQM
                     VSDAETVFVNFYDGSVRSQDFNSNWKFFLGNAGNAQEVNFDDSKWKAVSLPHDYSIEQ
                     DYSPNMEAESGYLPGGTGWYRKNFTVPKEAATKQVRVDFDGVYMNATVYINGHQVGTH
                     PYGYSPFSFDLTPYLNYGGDNVIAVKVDHKTPSSRWYSGSGIYRDVKLTITPMVHEAL
                     HGTKVELPNLESNQSNPSVHVETAVQNESGSEAEVTVSHRIYRKDDDSKTPIGEITAD
                     PVKVASGATVTVESDMTASNPDLWTLDDPDPQLYVMETTVSTGTTTDVTTSDFGFRYF
                     DFDSSTGFSLNGKNMKLKGVCMHHDQGSLGAEAWDRAIERQVEILKDMGCNAIRVTHN
                     PAAQDLIDICNEKGMLVIEEMFDGWHGSKNGNNEDYAKWYGKNIEDGNLIIGQEEGGM
                     TWAEFDMKSVIRRDWNAPSVISWSLGNEVMEGIGIGVGDYPNQAQKLIAWAVETDDTR
                     PVTTGDNKLKSGLAQSQQIGEKLAAADGLVGFNYTALNGSNTLSDYHAKHPDWNIYGS
                     ETASSINSRGVYKPSLYDRQLTAYDESKVGWGHFASDAWYTTIQKDFVAGEFVWTGFD
                     YIGEPTNWNGVGSGAVGTWPSPKNSYFGIIDTAGLPKDSYYLYQSLWNEYENTLHILP
                     AWNGDVIEKDDQGNVKVVVYSDAPTVDLFFTPEGGQETSLGSKTMTEKHSQADDGSEG
                     LYTYQMYEGDDKDNTAHKNLYRTWKVPYQDGTLRAVAKDASGREISNTVGRNVVKTAG
                     KAAKIEAEADRDRIDADGDDLSYITVTITDENGTMVPDADNRVKFTVEGDGKLVGLDN
                     GWTTDHDSYQADNRRAFNGQLVAIVQSTEEEGSFTLKAEADGLKGCEVTVDTDAVESG
                     ETDPGADNMVASYEISKNYYVKVGYEPVLPETLPVTYTDGTTAELSVVWDTIPQDKLD
                     EEGSFLLSGDMEGTKVSVSINMISQIAAILNYSTTVHLGEAPLLPESRQLVSEDGEIL
                     NIALPVEWDERPADDYKEEGIVTVNGTVSVFGEPMDVTASVRVQKEKAVITDNVGTKA
                     KVSQTVGTPSDALSAINDGSTKSVDNPSSPNNSRWSNWDYTKKTQNDPPAELQFVFDT
                     QETLGQIKIYFVRDNGSLRFPDPGITKIYVSNDMKQWTELHTLGVKETIPDKETSSMV
                     KCYTYDFAPLGATYLKLEIHNNKAGSAGAAGAEMPTTGITEVELYRSEGRFTVNSSTA
                     LSSLTLNGVKAPESALKAGEYNTPMSVVEELQAVSEENAAITVLPAADGQVKILLESE
                     DHSKMDEFIIHLEQDSTGSADDDSMDYPVKDMKVTVGNEHGTDKKENALDNNYGTVWH
                     TDWNNVTPVEKRWIQLELDKETNIDALRYYSRNDGPNGRVNKYKVEVSSDGKDWKTVS
                     TGNWKNEGGWKLAAFEEPVKAKFVKLTGVETYGNTANMFMSAAEVRVRTARETTKLTE
                     DNVTLSEDTFIMDEDQTPVKPEVSVSIDGKALRYGIDYTVNYENNDKPGIGTVIVKGI
                     MDYSGVIRLEFHIVGSNTQNVTVLDGTITKLDDQELEGQTQIEAESGRIVTVKADVKD
                     GMEFDHWRTAPANLLSKEDMKKEEVSFIIPESGSRLHAVYREEGEDKLSEEAYTTAEP
                     SNWFAFGDESDMEALLEAALTDSDEVILQKGGSAEVKMNLERSKKEPSKMDILKSYEL
                     LASPSDAEKEEDDDDKNVTSKATASNAEKSETVKASASDAEETLNPRDILKDEVLSPL
                     KAVKEEAGLNDDEEAARTTKIAFWIRTTAEKVVTNSAGNPTRTQLVDPKLPEVQITAE
                     LPKDDRRMEDYQVMRYEYSEDGTSVSVVSCEVEGNNLIFDAAPDGVYAVMYTQCFDVI
                     FEDYDKTVLSKQRVAYGNAAEAPEDPKREGYTFAGWNKDFDYVTSDMRIRAVYEEGEE
                     KPEVNKNRLEAKIEEIQRKMDALDEDDYTSSSWSKLEDALDEAIAVLEDEDATQTQVN
                     KAAEKLDKAYKALKRIGGGSSHSGGSGGSGHSSSRPLYGNSKPQPLDGGAYVTNGTWT
                     NVQDGWTFTKENGEKAVSCWIYTLWGDSYEWYYFNAEGKMATGWVEADGQTFYLNPVS
                     DGTRGKMMTGWQLIDGKYYYFNTVSDGTRGALYRNRTTPDGYQVGADGVWIQ"
     gene            26066..26779
                     /locus_tag="ACZPCR_04385"
     CDS             26066..26779
                     /locus_tag="ACZPCR_04385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002576802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HIR1230142.1"
                     /translation="MSEERLNENMENMETMADYEKEIEESFKKNEDTPVWEKFAKLME
                     EKTPLQVEIAEVVNGGVTAYVDGIRGFIPASKLAASYVENLEEWVGKTIDVLVITVEE
                     ERKKLVLSGRELAREKEQEEKKKRVEQCQVGAVMEGTVETIKDYGAFVRLENGLSGLV
                     HVSRISSQRVKHPGAVLKEGQTVKVKIVGIKDGKLSLSIRDAQEKEEEELQQEEFFDY
                     HENGQAATSLGSLLKGLKF"
     gene            26831..27517
                     /locus_tag="ACZPCR_04390"
     CDS             26831..27517
                     /locus_tag="ACZPCR_04390"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006427351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008728 - GTP diphosphokinase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HIR1230143.1"
                     /translation="MVNIPKSFNQMDQWKAVMFLYNSALKEINTKIEILNNEFVHIYS
                     YNPIEHIKSRLKTPESIVKKLKSDGREVTIPNMIDHLSDIAGIRIICSFTSDIYRIAD
                     MIARQSDVTVLYVKDYIKNPKPNGYKSYHMVVTIPIYLSEGPVDTKVEIQIRTVAMDF
                     WASLEHKIYYKFEGNAPDFLEKELKACADMVDLLDAKMFSLNEAIMKISAEQRLKEEE
                     EFRRSRETQE"
     gene            27542..27994
                     /gene="dtd"
                     /locus_tag="ACZPCR_04395"
     CDS             27542..27994
                     /gene="dtd"
                     /locus_tag="ACZPCR_04395"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - peptidyl-tRNA hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HIR1230144.1"
                     /translation="MKIVLQRVTQASVTVDGQVIGKIGQGFLVLLGVCDTDTEAIADK
                     MVDKLCKLRIFQDDQGKTNLSLADVGGELLVVSQFTLYADCRKGNRPSFVKAGAPGMA
                     NRLYEYVVEKCKGYVNRVEHGEFGADMKVELLNDGPFTLVLDSEEICR"
     gene            28116..29504
                     /locus_tag="ACZPCR_04400"
     CDS             28116..29504
                     /locus_tag="ACZPCR_04400"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009219423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HIR1230145.1"
                     /translation="MDESVKELQKQLTWEFPHIAKEAPDQTKEAAEYCEGYKAFLNKA
                     KTEREFVAEAVRILSENGYQEYEIGKKYETGDKVYFINRKKALIMTTFGCRPLEEGIR
                     LNIAHIDSPRLDLKPNPLYEKTDLAFLKTHYYGGIRKYQWATIPLAMHGVVITKDGTA
                     VDICIGEDEGDPVFCVTDLLPHLAAEQNERKLKDGIKGEELNVLVGSIPYAGEEIKEP
                     VKLLVLKLLNEKYGMTEKDFTRAEIEMVPAVKATDVGLDRSLVGAYGQDDKVCAYTAM
                     TAEMATEKPEYTTVTVLADKEEIGSVGNTGLDSDFSLHYIEYLADAAGADVKTVLRNS
                     ICLSSDVNAAYDPTFASVYEEKNSCYVNKGCVLTKYTGARGKSGSNDASAETMAKVID
                     IMDREGVYWQIGELGAVDVGGGGTVACYVAKMDVDVVDLGVPILAMHAPFELASKLDI
                     YNTYKAFKAFYK"
     gene            29698..30810
                     /gene="tig"
                     /locus_tag="ACZPCR_04405"
     CDS             29698..30810
                     /gene="tig"
                     /locus_tag="ACZPCR_04405"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HIR1230146.1"
                     /translation="MRKFVKAGLAGLAALMLMTGCGAKEQTATPSDAESKAEGGEEAS
                     EEYIAEGSITLGEYKNLPVTVVNPTISDEELQGRIDTVLGGYATWDAVDREAADGDRV
                     KIDYKGLKDGEAFEGGTAEGYTLVLGSNTFIDGFEEGLIGVKAGEERDLNLTFPEDYQ
                     AEDLAGQDVVFEVKIHEVAEKHVPELTDEFVAENFPELGTVDAYKADLKQQMLDAKTM
                     QSEQQRDAELLAAVVENSEIACATDEVNEVYDQQIQYYTSMAGMYGMGLADYAAMMGM
                     DEDGFRTEVRKMSEQTVKQQMALMEIAKKEKLTVEDADREALAEEYKDAYESVDDMIE
                     KAGAENVDNAILYDKAIQVVVDNADVTNVDGLAVAE"
     gene            30837..31430
                     /locus_tag="ACZPCR_04410"
     CDS             30837..31430
                     /locus_tag="ACZPCR_04410"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006782387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HIR1230147.1"
                     /translation="MQMLYDRIRRDGVVRAGNVLKVDRFLNHQMDIELFKEIGKEFKR
                     RFADVEVNKILTIEASGIGIACIVAQYFNVPVVFAKKTKTKNIAGDVYTTKVESFTHG
                     TVYDIIVSKEFLGKGDKVLVIDDFLAKGKALDGLTTLIQNSGAELVGAGIVIEKGFQC
                     GGDIIRQKGIRLESLAIVDSMDETTGEIVFRGEEKQA"
     gene            31472..32269
                     /locus_tag="ACZPCR_04415"
     CDS             31472..32269
                     /locus_tag="ACZPCR_04415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007718867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HIR1230148.1"
                     /translation="MGNRKALFFDIDGTLLSEGRDRKVPESARKALLQAREKGHLVFV
                     NTGRTWCETKEVRHLIDADGWLCGCGTYLMAEGEVLYDWRISPERGDQLIKLIRDCGM
                     DGVLEGVEACYMQKAPSPTRAVEQCRQDFSALGIVSEKTWDDEDISFSKFCLVTDENS
                     CLERFKEETREDLEVIDRGSAFVEVVPRGHSKAAAIERILGRYGLALEDAWVFGDSMN
                     DLSMFQYARNAVLMGRHDKELEPYASFITKTVEEDGIAFAMEKFGLI"
     gene            complement(32384..33724)
                     /gene="hutI"
                     /locus_tag="ACZPCR_04420"
     CDS             complement(32384..33724)
                     /gene="hutI"
                     /locus_tag="ACZPCR_04420"
                     /EC_number="3.5.2.7"
                     /inference="COORDINATES: protein motif:HMM:TIGR01224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016812 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in cyclic amides
                     [Evidence IEA];
                     GO_function: GO:0050480 - imidazolonepropionase activity
                     [Evidence IEA];
                     GO_process: GO:0019556 - L-histidine catabolic process to
                     glutamate and formamide [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazolonepropionase"
                     /protein_id="HIR1230149.1"
                     /translation="MKKLYIRHASELVTCRGKAPRRGREMADIGLIEDGAVLLSDGRI
                     EAVGTTKELDQRLGLDPKQADALHHETASISSQAAEPADTELNGQPATTLNAWGKTVL
                     PGFVDSHTHFIFGGFRADEFSWRLKGDSYMSIMERGGGINATIRPTKEASEEDLIAAG
                     MDRLNRMAEFGVTTVEGKSGYGMDCETELKQLRVMKELDRRHPLDVVSTFLGPHSVLP
                     EYKGREREFLDYMLTQVMPLAKKENLAEFADIFCEKNVFSIEDSEYYLNQAKKLGFRL
                     KIHADEMYPLGGGELAARAGAVSADHLLKASDEGIRQMAEAGVISTLLPATAFCLKEE
                     YAPARKMIDSGCAVALASDLNPGSCFTNSIPLLIALGCIYMNMSIEEVITALTINGAA
                     AVGRADTIGSIEEGKQADILIMKYPSIAYLPYHTAVNQVETVIKKGEIIVSKRW"
     gene            complement(33748..35775)
                     /locus_tag="ACZPCR_04425"
     CDS             complement(33748..35775)
                     /locus_tag="ACZPCR_04425"
                     /EC_number="4.2.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008397649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016153 - urocanate hydratase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="urocanate hydratase"
                     /protein_id="HIR1230150.1"
                     /translation="MNNKEIGAAMTIKLDPVLPEYPVFKEGIRRAPMRELTLNEREIK
                     LAVKNALRYVPEELHKDLAPEFMEELLTRGRIYGYRFMPKERIYGKPIDEYKGNCVQG
                     KAFQVMIDNNLNHDVALYPYELVTYGETGQVCQNWMQYQLIKKYLEILTDEQTLVVMS
                     GHPLGLFKSHKSSPRVVITNGLMVGEGDNPEAWAKATAMGCSSYGQMTAGGWMYIGPQ
                     GIVHGTFNTILNAGRKFLGVPHDGDLAGHLFVTSGLGGMSGAQPKAIEIAGGVGIIAE
                     VDYSRIETRHSQGWVSLITESAEEAFRLAADYMKRKETISIAYHGNIVDLLQYAVDHE
                     MKIELLSDQTSCHVPYDGGYCPQGLTFEERTEMLAHDKERFAELVNASLIKHFHLIKE
                     LVKRGAYFFDYGNSFMKAVFDAGAKDIAKNGTDTSEGFIFPSYVEDIMGPELFDYGYG
                     PFRWCCLSGKHEDLVKTDHAAMEIINPNRRPQDKDNWIWIRDAEKNQLVVGTQCRILY
                     QDAFGRRDIALKFNEMVRNGEIGPVMLGRDHHDTGGTDSPYRETSNIYDGSNMTADMA
                     VQCYAGNAARGMSLIALHNGGGTGIGKAINGGFGLVLDGTAETDAIIREAIPWDTMVG
                     VSRRNWARNEHSIETVAEYNQMRKGSDVITMPYIADDELIEKAYQNAVNRQ"
     gene            35964..38966
                     /locus_tag="ACZPCR_04430"
     CDS             35964..38966
                     /locus_tag="ACZPCR_04430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008397647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HIR1230151.1"
                     /translation="MEEIAVQLFGIPEIRLGDEKIRFPYKKAEAFFYYLCVRKKVSRD
                     QVICLLWGDEDETSGKKKLRDAVYQVKRLLGKDLLLTGGHTEIELNPQAPLRTDWEKQ
                     EEPENEGEFLDHFYIKNCYEFEEWAEEIRTRIRKRRAEEARRRMEKAAVEKDDASLQK
                     YSNFLLAEDPYNEELYFETMSLYAENGSYTMAIRLYNDLKRRLSRDLSEEPSKGLKEL
                     FQRIYNMKETVQAGEAGLTLSFVGRKRELYQLSGFLSGREGAESVLAVCGESGSGKTA
                     FLEQGIRLASGDGFTVLKTACYKQGEEFYLSPWNDIFQELYQLSERENQAGGAGEILE
                     QFLNGAKAEEGKASRMTYPMVEKMALDLLQALSKRRRILLVFDDIQWMDSMSGQLLNR
                     VLLRLGRERLLLLCSMSREGEGRTLESLEPLLLKDQVAILRLEPFTREETDELIRKTL
                     PDLASEEEKKAEIYRATDGNAFFLRELLTLIREKGYTLEKSKKTNYVIQARLSGLSRQ
                     ERETLGAMAVFPGKIQVEDLELLLPDTDRLSLLRLLESLQERFLIREVLTGWNVQYEF
                     VHRAFQEYVCEQQSRGKTQLYHQILARHYEEKALQSRETTLFPQVIYHYEGCHDLIRA
                     CWYKIEWMKEYYTLINENFPVLHWQVADLSEGVGVMPQADEMIRLAGEIMDLQGSSEK
                     IRRMKLEMNYILGRYHIAQGEYRQGLFHIEEGIRLAKELSDTRMLLSCFRQQIFYGIQ
                     VEDLERVKTYVEMGIEKVKENSPLREAFLSLEWELEHSSGQTLEETLRERLKESRGDG
                     ALQDDDVKDWEEYGTFLRLKGWYLLHSQTDSQAERTLWAAADIFKGLGSGCEPGRAAC
                     LSYIGDSMDRQGRFLEAVSFYEQAIALVEKNPRINGLGQFYARAGQALFMAGNTEKGR
                     EYLEQAEKRLKENGCVWGLERTEALLCLISLSEMNLEEAERRFYEGMELSEKIRNPQT
                     QKLLETARQKLRKRGAQLQKRFGADGFS"
     gene            39040..40572
                     /gene="hutH"
                     /locus_tag="ACZPCR_04435"
     CDS             39040..40572
                     /gene="hutH"
                     /locus_tag="ACZPCR_04435"
                     /EC_number="4.3.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004397 - histidine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006548 - L-histidine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ammonia-lyase"
                     /protein_id="HIR1230152.1"
                     /translation="MNKVLITGEDLTLDEIVSVCRGNAQVEISQEAREKVQASRQVVD
                     DLIAEEKVVYGITTGFGKFSDVVISQDQCKELQKNLIITHAVGAGDPFSRDIARGIML
                     LRINNLSKGFSGIRMETLQTMAYMLNKGVTPIIPEKGSLGASGDLAPLSHMVLPMIGL
                     GLAEYQGEVLPGKEAMDRAGIPVIELSAKEGLALNNGTQAMTSAGSLALYDALDLIKT
                     ADIAAALSFEAQNGVVDALDPRVHKVRPHSGQMATARNLLALLEGSKNTTRQGQIRVQ
                     DAYSLRCCPQIHGASKDAVQYVKDKVDIEINSVTDNPIIFKDDHAGISGGNFHGQPMA
                     LSFDFLGIAESELANVSERRIERLVNPAYSGLPAFLTPNGGVCSGFMIVQYSAAALVS
                     ENKVLAHPASVDSIPSSAGQEDHVSMGTIAARKAGEIGRNVRRVLAMELMVACQGIDM
                     RGNKGLGKGTQAAYDLVRKAVAALEDDRELYDDINYCEKIIEDGSLIRAVEAALGREI
                     EV"
     gene            40759..41139
                     /locus_tag="ACZPCR_04440"
     CDS             40759..41139
                     /locus_tag="ACZPCR_04440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002601070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAC/SpoIIIAD family protein"
                     /protein_id="HIR1230153.1"
                     /translation="METAAAVGIIAVLTAVQFKSRGTEFGIYVILAAGVLIFFYSAGK
                     LRIILEAVRQIQSCIQMNQAYLTALLKMAGITYIAELASGLCRDAGYSSMGTQIEMFG
                     KLSILAVSVPIVLALFETLESFLE"
     gene            41167..42375
                     /locus_tag="ACZPCR_04445"
     CDS             41167..42375
                     /locus_tag="ACZPCR_04445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HIR1230154.1"
                     /translation="MSRIALCLGLAAALFFSCPWRAAGEERGGAGEWEEKTRQEDNGG
                     EEELSALEGMELDFSSVEELLGSRKQGEGRFSFEELLKAVFRGDMKEACSMAFHGISD
                     SLFSELSAGAGQMAKILLIALTGAVFTCFSDIFSGGQISETAFYVTFLLLFSLLASSF
                     YESIAVADQAVSQAFELMKALTPGYFMTVAFTGGSLSAGASCGWMLFSITAAQWLLSH
                     LIFPVFRVYILLVLAGHLTKEGVFSRMTEGIRTAVEWSMKTLTGAVLGFHLLQGMVLP
                     YADAVKNASLKRMVSMIPGLGQGAFTVSQMVLGSGILIKNTVGAGAALALLAVTAVPM
                     IKLFVLMLMYHLMAAAAEPICDKQLTACMADVGKGHQILLKLVFTSLLLLVVSIGVIC
                     MASNASYYAA"
     gene            42446..43156
                     /locus_tag="ACZPCR_04450"
     CDS             42446..43156
                     /locus_tag="ACZPCR_04450"
                     /inference="COORDINATES: protein motif:HMM:NF021121.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HIR1230155.1"
                     /translation="MNFMTNLLPGKAYARYVRLFMGMVLILLVIRPLTGSLRLDEQLA
                     RRFEEISFQKEAGELQGQLEEIERQRFETIADEYEKTVSAQAEERLEKSGYGGAQVKV
                     SVDREQGSDSFGMIEEMEVSVEDVEAWEYSAGEMPESDEINNQLKQLEKTQQLKQTKQ
                     SEKEQEIRQVSIEKNQIQVHLGNKEESEEKGEEGQERLENSCGADTGDPDAEAAIRKE
                     LADFYGLEERHIKIQIRD"
     gene            43113..43796
                     /locus_tag="ACZPCR_04455"
     CDS             43113..43796
                     /locus_tag="ACZPCR_04455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HIR1230156.1"
                     /translation="MDWKSVILKFKSGTEKKKRDQWIVLFAAGLLLLLFSASGSGKPA
                     HRKEDLPVSGEVLEKMDRTGANDNDRGRETGGGNDGSGREQEEKDAEASALSAYEKQL
                     EERVKELLRMTEGVGEADVMIVLKSSGEKIIHEDQKRRRASSEETDSAGGTRKTVDEE
                     AEKSAVFVENGSEKEPIVEKELRPAVEGVVISAQGGGNASVKTEISEAMQALFNIPAH
                     KIKVLKRVD"
     gene            43810..44610
                     /locus_tag="ACZPCR_04460"
     CDS             43810..44610
                     /locus_tag="ACZPCR_04460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HIR1230157.1"
                     /translation="MKVKRIFRRNQIIITTLAIMIAAAGYLNYSGKEELSGAVYEAGV
                     MEISDEDILAENQAVGNLNPEAEGAGEEVSGPAEAETKQPGAQQAEAQQGKEGESSVS
                     AGSAEAEEYKEIASLDQEPGEEAGSEQADSSIDNPGEAVLTGGTSVTDYIANVQLSRE
                     QVRAKNKETLMEIINNENADPQAKETAVQDMIDMTAVAEKENAAETLLMAKGFADPVV
                     SITDGKVDVVINASSLTDPERAQIEDIVKRKAEVTAENIVITLMKLQE"
     gene            44686..45075
                     /locus_tag="ACZPCR_04465"
     CDS             44686..45075
                     /locus_tag="ACZPCR_04465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005610159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HIR1230158.1"
                     /translation="MPKEAAEKNIHVLERDGKLGEVKIADEVVAMIAGLAATEVEGVD
                     SMAGNITNELVGKLGMKNLSKGVKVEVSEEHVSVDLSLNMKYGYSLPAVSEKVQERVR
                     TAIETMTGLTVLEVNIKIAGVNMREES"
     gene            45437..46573
                     /locus_tag="ACZPCR_04470"
     CDS             45437..46573
                     /locus_tag="ACZPCR_04470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HIR1230159.1"
                     /translation="MDFLLEGILAITPQQLVMYVVGVLLIWLAIKKGYEPSLLLPMGF
                     GAILVNLPLSGVINQVMEGVGETPGIIQWLFETTIEASEALPILLFIGIGAMIDFGPL
                     LSQPVMFLFGAAAQFGIFFAIMVAVLLGFDLKDAASIGIIGAADGPTSILVSQVLHSD
                     YVGAIAVAAYSYMALVPIIQPFAIKLVTTKKERCIHMTYSPKAVSKTTKIAFPIIVTI
                     IVGLISPASVALVGFLMFGNLIRECGVLQSMSDTAQNELANLITLLLGITISFSMRAD
                     AFVRFDTILIMCIGLVAFVFDTIGGVMFAKIINLFRKEKINPMIGGAGISAFPMSARV
                     IQKMAQEEEKGNIILMHAVGANVSGQIASVIAGGLVIKLVTQFL"
     gene            46587..46703
                     /locus_tag="ACZPCR_04475"
     CDS             46587..46703
                     /locus_tag="ACZPCR_04475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002605419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OadG-related small transporter subunit"
                     /protein_id="HIR1230160.1"
                     /translation="MMENFLIALQIMAQGMGGIFVVIILITLVVMLMGKMNK"
     gene            complement(46876..47268)
                     /locus_tag="ACZPCR_04480"
     CDS             complement(46876..47268)
                     /locus_tag="ACZPCR_04480"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230161.1"
                     /translation="MMEKIKRLNWYQKSVLVVMIAMALVFAVIYSMTISKVGFEYKDA
                     IFVPSQENGSTVYSGRLRGQKAYFSVSQDKTVVFHYGNKIYGPYTVKEDNTAIPEEEK
                     TLEGIVGVELRQGRLTGKLQEDIPPGLL"
     gene            complement(47483..>48251)
                     /locus_tag="ACZPCR_04485"
     CDS             complement(47483..>48251)
                     /locus_tag="ACZPCR_04485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015561012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HIR1230162.1"
                     /translation="RYRFDKVKERAKLKTSVSRLICILFPELEKLVPTLHMASVYALL
                     SEFPSAHAVASAHLTRLINLLSQSSKNRYGKDTAVMFREAARNSIGSNMPTKSLELKH
                     TIKLIQELTSEIDEIEAAIKQIMDEEIQSPILTIPGISYRMGAMIIAEIGDFCRFDSA
                     DKILAYAGMSPSTYQSGQLDNCYSHMEKRGSRYLRYALYNATKYVCHWDKSFGEYLAK
                     KRSEGKHYNVAISHAAKKLVRLIFAMEKSRKAYLPAT"
BASE COUNT        12824 a        10752 c        13599 g        11076 t
ORIGIN      
        1 gaagtaatcc cacatccgat aaaaaaaata aaaataatcc aactaacaag cggcacagct
       61 ttatagcgtt tgttcttaat aattaagaat gctgcagctg ctaacaatat cgttagtata
      121 tgaatcatga ttgccatatc cgtttttcca atactctttc ttttaatcct acttactgat
      181 atttttctta tgggttaatg tcaatgcaag aaattttttc ttcgctgtac ctctttacta
      241 gagttaaaat catgcgaata actgccacaa ccattcaata agcctaaata aaacacgcct
      301 gctataatac ttaatacaat tttttatatc gcataatcgc tgtttctatg taatttgata
      361 atttaatata gttctacaaa ctggaggttg tcagcctgta taagcatcat ctgccgtgtt
      421 cttaaaattc tgcttttcca accattgctt ttcttcttcg ctttccggaa tatcaatccg
      481 ctctattttg aagataacag ggcgtgtgcc gtcattgcag caggcgatca tcattctgtc
      541 gtcatttgtc cacttacgca taatggaacc accctgcagc gccgcataga catatcggct
      601 gatggcatcc catgcctcgc cgcagaattt gccgttcatt agattgtaaa agtcatcctg
      661 ctccggcgtt cttttcagaa ggaatgtctc tcccgccttg aagcaaggac acggacctga
      721 tttcggatca gccaaatact tttcctgcaa ttccggaaat acctttgtct ccaatactgt
      781 tattttgcat tcgtagttca taaaaacctt ctgagtcttc actgtgttga gttcattaaa
      841 tttcaatttt tctgtcctca ttatatcata agcatttttg ttttcacaga cgatataaag
      901 cacaaaagca caaaagcaga caacacaatg ccgcattcgt aatccgcttc gcttattgat
      961 caaatatgga tttcgccaaa tagaaatcaa aaatcaggaa aaccttgtga gcaagcttac
     1021 ggtttttcct gattttcgct ttctgcctga actcaatgct ccagcatatt ttcgataaaa
     1081 atgccatatc cgcgggtgga gtcctggatg aaaacgtgag taacggcgcc gaccagcttt
     1141 ccatcctgaa tgatggggct tccgctcatt ccctggacga tgccgccagt cagttccagc
     1201 agcctgggat ctgtcacttt gatgaccaga cttttatttt tgtgggaggt agagtaatcc
     1261 accttctgaa tctcgatttc atagtcttcc ggctttccgg aaatacagct tcggatatag
     1321 gcagttcctt tccttacgtc ctggcggtag ccgatgggga caggctcacg ccctggccct
     1381 gtgccgaaca tagttccgat ttctttccac atcttatttc cagctgtgcc gaaaatgccc
     1441 tgttctgtgt tggcgtcaat ggttccgagc tttgactggc ttccatagta gatgacgccg
     1501 gacagcacgc ctggctttcc catagatcct ttttcaattc ccatgatttc tgtgtcgtac
     1561 agctctcctc cgcaggtgtc taccagaagt cctgtgtcgc tgtcgctgat tccgtggccg
     1621 agagccccgt attctcccga ttcagttaca taggtcatgg taccgatccc ctgggtatcg
     1681 tcccggatcc agactcccag cttgtaatcg ccgttttccg tttccagagg cgtcatagtc
     1741 acgtccatct gtttttcgcc gcggcgcaca gtcagctgaa cgggggaatc ctgggccttg
     1801 gcgactgcct caatcatatc ttcttttttt ctggctggtt ctccgtttat ggcttcaata
     1861 taatcccctg actggagaag tccctgggca ggatcaaagg aggagccgtc tttcgttttt
     1921 accggtcctg ttccaattac cataaggccg tctgatttca tatagatgcc caccggcatg
     1981 ccgcagggga gggcatattt ggtgtcagaa acattgactt caatatcctt aaaatggatg
     2041 agtccgaaca gctttaaatc cagccggtag attccctcgc tggcagagta gagggagaaa
     2101 ggatgattta tctgaagatg gagctgttct gcaggaatat tagaatcatt tcccaccact
     2161 acctcagagt tgtcactttc cagagtgacc ttcacaggga gaggaaaatg aaagctttcc
     2221 gcctcgtcta ccaccagatt gagccgatct ggaatggctt catttaagta aaaccaggta
     2281 aagcccaggg tgaatacaag gcttccccag aaaacagcgg tcagcagccg ctgaagcttt
     2341 tcttttctag tcacattcga ttcctcctta tcacaagtct tttgtcataa gccatctgtc
     2401 tgaatgcagc gattcagata tactctagta tgtgactaaa agcagaaaag aactcagcaa
     2461 atcgagggga gaaatatgga aacgaaacat agaactatta gataaaaata aaaacaaaca
     2521 aaaaaatatc agataacgga gtgggatttg gtgaaatatt gtcttgaatc atctgatttt
     2581 ggtgttataa tacaaatgta acagataaaa acttaatacg acctgaacga gaaagtgcag
     2641 agacacgcgc tctgaactgg attcgcccag aagccgctaa gcagtcagtt tgatggagga
     2701 aaagataaat gaatactttg aaagctgaga agagaagcat ggatgtgaag gccaaaaggc
     2761 ttagacggga aggatttgta acaggaaatg tatttggacg tgaaattaag ggttccatac
     2821 cagtaaaaat ttccaaaaat gaggcggaac gcctgttaaa gaccaacgga aaaggcagtc
     2881 aggttctgtt gaatgtagac ggaaccgaga tggacgttct gatcaaggag attgattaca
     2941 attctttaaa gggacaggtg gatgagatag attttcaggc gcttgtaagc ggtgagaagg
     3001 tacattctgt ggcagaaatt catctgctca atcatgaaaa agtgacaacc ggagtgcttc
     3061 agcagatgtt gaaggaggtt tcctaccgag cgcttccgtc agctctggta gaaaaaattg
     3121 agctggatgt aggcggcatg agagtgggag acacaatccg ggtacgggat ctggcgattg
     3181 cctctgacaa agatgtgcag ctgcagaccg atttggatac tgtggtagtc gaggtatacg
     3241 cttccaagaa tacggtggct gatgaggatg cagaagacgg aggatcagaa gcagagggaa
     3301 aatagatcaa gaagcctaaa agctgttaat attgcagaga gtagaagagg agtggcgcgg
     3361 tcattcctct ttttttagtt aagagaacgt tgcgccatgt gccgcctcga atctgcttcg
     3421 cagcttctcg ctggacggct ggcacggtgt gcagttaaaa tacataaaat aagccatgct
     3481 gccagctcga ttccgcctgg cggcttcatc tcgctggacg gctggcgtgg tgtgtagcta
     3541 aaatacataa aataagccac gcggccagct cgattccgcc tggcggcttc atctcgctgg
     3601 acggctggcg ccgtatgtgt ctaaaagcaa aaaagaaccc ggctggaaat gtaaacattc
     3661 ccctccgggt tctttcctgc ttttatccac gcatggcttg tagcttagcc aaagtatctc
     3721 tctaagagac cctggaatgc cttgccgtga cgagcctcat ctcttgccat ctcgtgaact
     3781 gtgtcatgga tagcgtcaag gttagctgcc ttagctctct tagccaggtc gaacttacca
     3841 gctgtagcac cgttctcagc ctctactctc atctcaaggt tcttctttgt ggaatctgtg
     3901 agaacctcgc cgagaagctc tgcaaactta gctgcgtgct cagcctcctc gtaagctgcc
     3961 ttctcccagt ataaaccgat ctctggatat ccctctctgt gagcaactct ggccatagca
     4021 aggtacatac caacctcctt gcactcgccc tcgtagttag ctcttaagtc ctccatgata
     4081 tcctcgcttg cgccctgagc aacgcctact acgtgctctg cagcccatgc catatcagct
     4141 gcctgctcct ggaacttgga agctggagcg ttacagactg gacatttctc cggagctgcc
     4201 tcaccctcgt aaacgtaacc acatactgta caaacaaatt tcttcatagc ttatactctc
     4261 ctttgcatat ataaaaattt ttaaaataca tatccataat caagactgtt ttgtttcact
     4321 ccccatgccg gcttatgcag cctggccgtg aaataaaaca gtaatgatta ctgatattaa
     4381 tgtaccacaa cttgtgggga ttgtcaatat ttattttata aaataaatat aaatttgtaa
     4441 attaatggga ttcttcctgc aggcagtcgc agcaggttcc ataaaagaaa acggtgtgtt
     4501 cctcaacagt tcccttctgg cactccctgg ccgcagcttc caggcctgta tcagtttcca
     4561 tggccaggtc cacgattttt ccgcactttt tacacacata gtggtagtgg ggggatgtgt
     4621 catagtcaaa atgatctgtt ccgtcaccgc aggaaagctt gcggatttcc cccagctcta
     4681 caagcaggtt taaatttcga tatacggttc ccagactgat attgggaaac tgttcgcgta
     4741 tgctggtgta taaagcgtcg gcggtgggat gatccttgcg gcccatcagg caggccttaa
     4801 tggattccct ctgacggctg tacttgaggg ttttcatagg tatttcctcc ttttcatctc
     4861 atctgccaat ctgacgcatt cagttgacaa aaaatagtaa taatagttac tgttttattt
     4921 tgccccagat ttgcctgttt gtcaatcctt tttttagaga gaaaatggtg atattgcatg
     4981 attttttgtt ggaagaggtc atagttagtg gtataattac ccatatacaa taagggaggt
     5041 acaggatgag taaaaaacag gtgcgccaaa tgatagagga gctgactgca aagctgtgcg
     5101 ccagagagtt tctggccgcg tcgaatctca gccgggagag cgttctgatg ctgatgaaca
     5161 gagagtactg ggaggggcag ctgggacgta ttttccctat taagagaaga attcagtgcc
     5221 gggagattta cgagatctgc agggaaccga tgagcctgat tggccgggag cccagggacg
     5281 ggtggatgaa attcacctac cagtacgtat gccatatcct gtatccagac gaagaatttt
     5341 ccagacaggc ggagccttac gccgccggag cactgtttta tctggctgtt ctccagttca
     5401 tctttgataa ggaaagggag gttctcccat ttgagcctat ggtggatttt gcattcctgt
     5461 cagaggaaga ggctctttcc tacgaatcct acacagaata caagaaattt aaaaatgctt
     5521 tttataaaga atacatttat gagatgatgc gtctgaacgc ggaagtgact cctttcagga
     5581 ctctggagca catcgcgggg gttcactatg tggccatgac ggtggccagg ggcctttatg
     5641 aggcaggcgt gcccattgac ctgactctga ccagcggagc tgcagcaggc cacgacctgg
     5701 gcaagttcgg gtgtaagccc aatgagagag tgccgtatct tcattattat tatacgaatc
     5761 agtggttcaa cagacaccgc atggaataca caggccacat tgcggccaat cattccacct
     5821 gggatctgga gccggaaaat ctgtcggtag agtcccttgt tctgatctac gcggacttcc
     5881 gggtgaagca gagcaggggg gaggacggcc gggagatcac ctatatttcc agcctggacg
     5941 aggccttcga gatcattttg tcgaagcttg acaatgtgga cgaggccaag ctgaaccgct
     6001 accggtttgt ctacgccaga ctccacgatt tcgagacgta catgcggtcc ctgggagtgg
     6061 acgtaaacct tgacaaaaag ccggtgaaga cgccgcctat gcctgacatt tccctgagaa
     6121 atacagagca gatcgtggat tccctgattt ttatgggagt ggagcacaac attgacgtga
     6181 tgcaccggat gggagcggag cgccagtttg gaaatcttct ggaggcggcc agaagtgaga
     6241 aaaactggaa gaacgtcagg gcctacctga acattttcca ggagtatttc ccctatacca
     6301 acgatatcca gaaggagcag actctctatt ttttatatga gcttctcatg cacaaggagg
     6361 gggacatcag aactcaggct gcccgcctga ttggaaacgt catcgcccag tttaacgcag
     6421 gctaccggaa ggagagacca gcggatatgc cggatatcgc ggatcagaag gctatggagc
     6481 tgtggaaaac cttcctgtcc atgattatct gcccggatca caagctgacg gtgcagcaca
     6541 agcgcagaat tgggtataat ttaaagcagg tgctgtcctc catggtggaa cacgcggcgt
     6601 ccgctgatat tgagggattt ctgcaggagt ttctgcgctg gtatgaagct ccggagaagc
     6661 gggagagcgg agaggccttc gtgctgctgg acgctctcca caatatgcct tttgagcggt
     6721 gcagcagaga gaacatggag cggatggcag aatttgcctg ctactatgct gtgcccaggg
     6781 agaacagctt cgagggcctt atcatcgccg cctggcgcgc ctttaagctg attacggcgg
     6841 aggtgaggga cgagccgttc tgtgaaacga ttgcagagat tgtggaacat gaagcgattg
     6901 cagaggacga tatcagccgc acgtttctcc agtacagaat cttgtctaat ctgggccgga
     6961 acgtatcccg ccaggaggag gcgctttacg gcagggacgt ggtttctgat attttcctgg
     7021 ataacctgaa gatggccacg ccgtgggtgc tgaaggcggt caatatcaag cttttagtgg
     7081 atcaggtgga tcacggaaag aaggagcata tcctccacat tgcggcccat ctgtccaacc
     7141 tgatcaaggt cagcgagtat gtggtagtgc gccatgacgc aggccgggcg ctgctcaggc
     7201 tggctcctct cctgacagcg gaccagagaa acgagattgt agtggagctg ttaaagggac
     7261 tggaggtagg agagtacgag ttttccaagt atattccaga gtacctggga cagctggccc
     7321 tgtggcttcc tccggaacag ctggaggagg ttttaaccta cctgcggggc ctgatggcca
     7381 atgccaacga ccgggtggtt tctgtggctc tggacacagt gggagtgctg acagaatatt
     7441 atccccgcta taaggagcgg tttgcagagg atgaggagac ggcgagagag cgtctgggac
     7501 ggcttttagg catggttctg ggaggtctgg caaaccacag agagacggtg cgccaggagg
     7561 cgcttctggt aacaggccag tatatgttcg gatccagaag gctcaatgac cacgagaaga
     7621 tggagatttt cgccctcacc cataaaaagc tgctcttcct gattaatgaa aacaagggcg
     7681 gagaactgac tgccttttac cgggcggctg ctctttccaa tatctgccgt tttattacag
     7741 cttaccgatt aaccattggc cagatggaga ttgaggagag gaagaaggtg gcgttcttcc
     7801 caggtacgtt cgacccgttt accctctccc acaagggaat cgtccgtgag atccgggatt
     7861 tgggctacga ggtttatctg gctgtggacg agttttcctg gtccaagaag acgcagcccc
     7921 acctgatccg ccgccagatt gtcaatatgt ctgtggcgga cgagttccat gtgaacctgt
     7981 tccccgacga tattccagtc aatatcgcca atccgtctga tttgaagcgg ctgaaggagg
     8041 tatttgcagg gcggaccgtc tatgtggtag tgggaagcga cgtcattgcc aacgcctcct
     8101 cctaccggaa gccgccggag aagaactcca ttcactccat gaaccacatc gccttccgcc
     8161 gggtgggaga caggagaagc gacaataaat acaaccggga gatgatgagc ctgattaccg
     8221 gggagcttat cgagctggag ctgccggagt atctggaaga catcagctcc acgaaaatca
     8281 gggagaatat cgatctgaac cgcgatattt ccaatctgat cgacccggtg gtgcaggaat
     8341 atatttattt taacggactg tatctgagag agccggagta caagccgatt ctccgtgcca
     8401 gagctatcgg ctttgaggag aaagaaaagc tttcagagga ggacgaggcg gctgcgctgg
     8461 agtatatttt cagtgacgag gcagacggcc gcggacttct gaaacgcctt caggagtctg
     8521 acggaacctt cctgcttctc agaaatacgg tggaggacaa tcggctgacc ggcctcctga
     8581 agatgcgttc tgtgatgccg gaggagctgt ttaaggtgct gggaagcgtt tccatggccg
     8641 acatggtgcg ccgtcatact ctgggaagca ttcttctgat tacaggaatc tacgcggagc
     8701 cggacagcgc aatctacgat ccggaacagc tgcttctgac agaggctctg gccaaggccc
     8761 tggagcagca ctgcagctac gccatgttcc tgcctgagga ggagccggga gaagcgtccc
     8821 agggagccgt catccgccag ggatttgcgg aggcggaaaa ctttgaggga aagagacgtc
     8881 tgtggctggt ggacatgcac gcgcctctgg tgctggtgca gaacctggag acgacgttaa
     8941 aggagccgtt ttccagcagt cccagaattt tgagagccat ccacaaggcc cacagggagc
     9001 tgcaggccgc catgacaagg ctctacccgg gccagctggt actgtctctg tcggccagcg
     9061 tgatttatca ccgcctggtg gacaagatta cccagattaa ccaggttcca ggggagccga
     9121 ccacgccgag agtgctggga aacgacatgt gcgttccctt tggaaagatc ctgagaggaa
     9181 aggttgttcc caatacagtg acgaagacca ttcacaccga taaggtgtac gagccggatc
     9241 tggacagcta ccggatcgag gccttcccct attattcgcc tctcagaagc caggtgagga
     9301 ctatcaaatc ctttggacgt cccgttatcc tggtggatga cctgcttcac aagggcggca
     9361 gatttgacgc cctggagccg tatctgcggg aagagggcgt ggaggtgaag aaggtgcttt
     9421 taggcatgat ttccggctac ggaagagacg ccatggccac cagaggcttt gaggcggaca
     9481 gcatttattc cattccgaat ctgaagttct ggtttgtgga atcgacgctt tatcccttta
     9541 tcggaggcga taccgtgcgc cgcgatacca tgaaggtggc gggcctgatg ccatctgtga
     9601 acattgtgct gccctacatg gttccgccat taaagggctg cagtgaggaa tcgctgttcg
     9661 agctgtcggc ctgctgcgtg agaaattcca gggatattct gttggccctg gagtctgagt
     9721 accgggcttt gtttggcaga aacctgactc tttccagact gtcggaggcg gttatcctgc
     9781 ctctctgccc ggataaggga gactgcataa actacgatcc gaacctggcg gcgtctgttt
     9841 atctggacaa cgatctggaa atgcttcacc gcatcagcca gctgaaaaat ctgtaaatct
     9901 gcaagatttc aaatagattt atctaaacta tctaagagga ggacaatgag tatgttttat
     9961 taccgcatca acggaacact ctgctgcagc ttaaatgggg agctggactt tcccagagag
    10021 gagctttacg gccgcggcac agatgaaaaa gaggccagag aaaaggcgtc cggcgaggag
    10081 gaactggtat ttctgtttga gcgttctcct aaaaactgcc gcgcttcctt ccgcgtgacg
    10141 gatccggccc tgctctacca ggatcgggag gacgtttcct ggctgaataa gaatgtcctg
    10201 ggggagggaa tgcgcgacga gattgtagat tcctttatta aagaaggaaa aatgcgcgca
    10261 gtgaatttaa accatcccag attccaggaa attctcaaag agaagccgga aaagaaaaag
    10321 aaacgtgtcc atgtactggc catcggagat gtgggaagta ctcttttgac aggcctccat
    10381 ctgttaggag gagatgtgat aagctccatc ggaatctgcg atatctccga caaggtgacg
    10441 gcccgctggg aatttgagga aaaccagatc gcctatccct gggactacga cgcgcttcca
    10501 gaggtagacg tggtgaagcc ggaggagctg ttccagtgcg atgtgttcgt attcgtggcc
    10561 tccaagggaa tcccgccggt aggttctgag gtcaaggatg tgagaatgta tcagtttgag
    10621 aataattcca agatcgtggc ccagtacgcc cgccaggcca gggaggaaaa atttaagggc
    10681 ctgttcgccg ttgtgtccga tccggtggat ccgctggcaa aggcggctta tctggccagc
    10741 aatacagaca agaacggcgt ttttgaccag aagggactgc gcccggagca gattcagggc
    10801 tacggtctgg gtgtcatgaa cgccagagcg gcctactatg caaagagaga cgagcggttt
    10861 aagcagtttc tgacagaggg gcgcagcttc ggcccccacg gccaggatct ggtggtggcc
    10921 gattccattg aacactacaa cgacgagctg tcaaaggagc tgactcagct gacagtgaca
    10981 gccaatctcc atatgagagc cattggtttt aagcccttta tcgctccggc ctattcctcc
    11041 ggcgccattt ccctgattct cacgctccgg ggagagtggc actgcggatc cgtgttctta
    11101 ggcggaattt tcatgggagt gaagaaccgc tacacggttc acggactgga gacggagatc
    11161 cttcctctgc cggatgctct gtatgagagg atcgtgacgg cgcaggagaa tttaaaagca
    11221 gtaaattagg cgtccggacg cagaaatcga ggggaaataa gatggaacag gaagaacgcg
    11281 agacagaaac agagaaaaca gatggggaaa tcctgctgat ccgccccaga gagcctggag
    11341 ggcgggaaaa ttcccgcctt ctgaaagcac ttcgtgaggg gcttgcaggc gtgcgtctgc
    11401 aggaggtgac ggaggtttcc cagctggaag ccatgacaga cgagagcggc cgcctggccc
    11461 cggaagggtg gacgggaaaa catctggcgc tgtttgccat agatctggga gaatacggcg
    11521 tgaatcttga atataccagg ctgttaggct ggctgagaag ccatccaaag agcctggagg
    11581 gctggaccgg cggagtgacg gcggacgcgg acagcgatct gtacaccaaa tctgcggcca
    11641 gagagctggt atttacggcc aaccgcgccg gctgcgcctt tgtgggccgt ccattagtgg
    11701 agggcacgaa aaccctgtcc aactttgcaa tcgtggcgtc caatctgggt acggatctgt
    11761 acggcgccta tgtggagagc ataaaacttc tggtgaagga gatggccaag agccagaagc
    11821 cggataaaga gaggaaaagg gaacttctgg tactccacgc ctccagccat aaaagctcca
    11881 atacctacgc cgtctggcag ggagtaaagc agtatctgac ggatatttcc atcacggaga
    11941 tcggactgcg caacggaacg ctggcagact gctccggctg tccttataag atgtgcctcc
    12001 actttggaga gaggggaagc tgcttttacg gaggcgtgat ggtagaaaac gtatatcccg
    12061 ccgtgaaaaa ggcagacggt atcctgcttc tggcccccaa ttacaacgac gctctgtccg
    12121 ccaacctgac ggccttcatc aaccgtctga ccgctctgtt ccggacgacc cgcttctatg
    12181 ataaaaagct gtttggaatt gtggtatcag gctattcagg cagcgatctg attgcggaac
    12241 agatgatagc ggcgttaaat atgaataaaa ccttttatct gccggggcat ttcgccatgc
    12301 tggagacggc caaccatccg ggagaagcca tgaagcttcc gggaattgag gagcggatga
    12361 gacagtatgc aaaacgcata cagaacaatc tgtgaaatac aaaactttac agaccgtcaa
    12421 aaagaaagta tactaaaggc tgatattttt ttattaaata gaacggaaag gcagtttcgc
    12481 catgaaactg taggattcag gggatataga gtatgagtat cagacaatgg aagcgcaccc
    12541 ttgccatcgg aggagtgatt gccctcacat cccagctgta ctggaacgcg tttattgatt
    12601 attttcgaat ttccacctcc gtgatcctgc ttcctgtcct gctgatgaca gtggggctgg
    12661 agctgcacac cttgaccacc tgctttgtca catcggtgat tgtgtttacc gtgcgttttc
    12721 tcattcagtc cggaagcgcc ggcatgacgt ggcagacggc gctctatgtg ctccccggcg
    12781 cgctgtttta tttaagctat ggagtgattt tcaagctctg catcaggaac cggcgggcca
    12841 cgactagaaa gaagcttttg tggactattt tcctgtctga tttcggagcg aatctcatcg
    12901 aggcagagat gcaggagtat ctgcagtttc gaaccctcga cgagcatatt attatttatc
    12961 tggcagtgat tgccgcgatc cggaccatgt ttgcctgcat gcttctggtg ggagaacggc
    13021 agtaccgggc ccttctgaaa aagaatgagc atgaacggcg ttatcagaga ctgtttctga
    13081 tgaaaacagg ccttaaaaat gaaatctact ttatgaggaa aaactctgag gagattgagt
    13141 cagttatggc caacgcctac aagctctacg aaaagctctg cgagcagaag ctcccagacg
    13201 agatgaagca gatgtccctt gccatagcca gggacgtcca tgagataaaa aaagattact
    13261 tccgcattat ccagggaatt gaggaggaga ttggaagcga atacgaggag gagagcatga
    13321 gctttcagga tattcttcag attctccagt cctccaccta ccacatgatt gcggccaaag
    13381 ggctggatat taagctggtg tttagctgta acgataattt tatcacccgc ggccactaca
    13441 ctctgatggc agtgttaaaa aatctggtca ataacgcgat tgaggccatt gagagcggaa
    13501 aaaagccggg ccaggtgaga atattagaaa agaaggaaaa cggagtctat atattccagg
    13561 tggaggacaa tggaccaggc atttcggagc gccatctgcc caacattttc gagatgggat
    13621 attcgacaaa gtttgactat aagacgggaa acatctaccg gggcgtagga ctctggggag
    13681 tcagaaatac ggtggaggag cagtttaagg gaacaatcaa cgtggtttca cagcctggaa
    13741 agggaaccag atttcaggtg gaaatccctg ccgagagatt agaggagtca taatatggag
    13801 atttatattg tagaagacga cagaacggta atcaatattc tggaagatat aatagaaacc
    13861 aacgggctgg gaactgtctg cggcacctcc ggcgggcagc cggcggacat ggaggagatt
    13921 gtgcgcctga atccggacgt ggttctggtg gatttcctga tgccggaaaa ggacggcatt
    13981 cagctggtga gagagctgaa ggaggccggc tgcggttcgc ggtttattat gatttctcag
    14041 gtgtcggcca aggagctgat agggaaggcc tacagcgccg gaattgattt ctttatcagc
    14101 aagccgatca atattataga agtaaaatct gtcatcgaaa acgtggagcg ccagatccag
    14161 aacgagcgga ccctctccaa catcaggaaa atgctcctgg ctgaaatgaa ggaggaggtt
    14221 ccggaagaga agaagaaaaa cgacgggtat gtgaagaagc tgcaggtgat tttaaaccgg
    14281 atcggcatgt cgggagagaa gggctgcgac gatatcatca aaatctgcca gtatctccac
    14341 gccaaccata agccaatctc ccaggtcagc atcggccagc tgtgcgagat tctgagcgcc
    14401 gcgcccaaga acatggagca gagagtgcgc cgcgccattg ccgtaggcat ggcgaatctg
    14461 gcccacatgg gcatcgagga cttcatgaac gagacgttta cagcctattc cggcacactg
    14521 ttccccttcg aggagatccg cgcggagatg gatcacatcc gcggaaagcg caaatacgga
    14581 ggaaaggtca gcattaaaaa gttcattgac agcctgatgc tggcggcaga cagggaatcc
    14641 cgcttctaaa gcggggatcc tgcctggaaa aaataaacac ttcataaact ttctgaaaaa
    14701 atcctttcac ttttttaaca aattcctgtt tttttttgta gtattttgta agccatatgg
    14761 taaagtacca ccataaaaat attggaggta atatatatgg cacccatttt agaacttgat
    14821 atgtatcagg caactgcggt cgcagctctc gtgcttcttc tgggacgttt ccttgtaaag
    14881 aagattccga ttctggatcg ttactgtatc ccagcgccgg ttgtgggcgg ctttgtttat
    14941 gcgattgtcc actgtattgt aagatcggcc ggaattatcg agatcagcgc ggacatgaca
    15001 ttaaagaatg ttttcatggt aggtttcttc tgcagcgttg gttttacagc atccttcaga
    15061 atgttaaaga agggcggtat tcagactatt gttttccttg gccttgcctt agctatggta
    15121 gtgcttcaga atattctggg agcaggcctt gccacagcgt tcggccttga tccgagactg
    15181 ggtcttgcta caggttccat cccgatggta ggcggacacg gaacagcagg ttccttcgga
    15241 ccgcttcttg aggatttagg cgtagctaac gcaaacgtag tagctatcgc ttccgcaaca
    15301 ttcggactgg tagcaggctg cgccatcggc ggacctatcg ctacaggtaa gattaagaaa
    15361 tttaaattac attctacaga gatgtcagca gagggcggat ttgagacaga ggacgcagga
    15421 aagatcgatt ccaagagatt cctggatgca gttctggctc tgattattgc aattggtttt
    15481 ggtacaatcg tttccatgct tcttggaaag ctgatgactt tcccattcta catcggcgct
    15541 atgttagtcg gagcagtaat ccgcaacgta gctgacgttg ccaagaagga gcttccgatg
    15601 gaggagatcg gcgtagtagg cggtttctgt ctgtccgtat tcctgggact tgccatgatc
    15661 gacatgaagt tatggcagct ggcagagctg gctcttccgt tagtagttat gttagcggct
    15721 cagaccgttc tcatgttctt atacgctaac tttgttgtat tcaacgtatt aggacgcaac
    15781 tacgatgcag cagttatgac aacaggtttc tgcggtttcg gtatgggcgc tactccaaac
    15841 gccatggcaa acatgcaggc agtagtagga cagtatggac cggctccgac tgcattcatg
    15901 gtagtgccgt tagtaggttc cctgttcatc gatttcttaa acgctacgat cctgacagga
    15961 ttcatcaact tcttaggcta attcagtatc catatacaaa cactcagccg gtcctatggg
    16021 ccggctgttt actgcttgga agcagcgcgg caggacgctt ttctcacagc cggcaggcgc
    16081 tgattcaggc tcaggacgcc tgttattatg taatataaat gaaatataat aatatttata
    16141 atgcgatatt aatttgatta tgcacagaca atgagttata attaaaacag aacgtaagat
    16201 tttcacaaaa acagtagatt ttttgtttct tttttgttac aatgtagaca tgaagcaaag
    16261 agactatact gttgagtgaa aactcacaat attaatgcaa aagcaggagg tattatccaa
    16321 tgagcaagta tgttgacaga gttcttgcag aactcaaaga gaaaaatgca catgaagccg
    16381 aattccttca gacagcagag gaagtattat ccactctggg tccggttgta gatgcacatc
    16441 cggagtacga gaaggctgct cttcttgaga gaatggttga gccggagaga actatcgagt
    16501 tccgtgtacc gtgggtagat gacaacggcg ctgtccatgt aaaccgtggc tatcgtgtac
    16561 agttcaacgg cgctattgga ccgtacaaag gaggcttacg tttcgctcct tctgtaaacc
    16621 tgtctatcat gaaattctta ggcttcgagc agactttcaa aaacagctta acaaccctgc
    16681 cgatgggcgg tgctaagggt ggttctgact tcgatccgaa cggcaagagc gatgcagagg
    16741 ttatgagatt ctgccagtcc ttcatgactg agttatatcg tcacatcgga ccggacgtag
    16801 atatcccggc tggtgacctt ggtgtaggtg ctcgtgagat cggttacctg tatggccagt
    16861 acagaaagat ccgtggtgca ttcgagaacg gtactatcac tggtaaggga atgtccttcg
    16921 gtggttctct ggtacgtccg gaagcaactg gttacggtgc tgtatactat acagaggctg
    16981 ttatgaaaca tgagaacgat acaatcgaag gcaagagcgt tgttgtatct ggtttcggta
    17041 acgttgcttg gggtatctgc aagaaactgg ctgagctggg tgctaaggct gttaccctgt
    17101 ctggtccgga cggatacatc tacgatccgg aaggtgttgt aactgaagag aagatcaact
    17161 acatgctgga gatgagagca tctggacgta acaaagttca ggattacgca gacaagttcg
    17221 gcgtacagtt cttcccaggt gagaaaccgt tcggcgttaa ggctgacatc gttatgccgg
    17281 ctgctactca gaacgatgtt cgtatggaag aggctaagaa gatggttgct aacggcctta
    17341 agtactatat cgaggttgct aacatgccaa ctacaaacga ggctcttaag ttcttaatgg
    17401 agcagccgaa catggtagta gctccgtcca aggctgtaaa cgcaggtggt gttcttgtat
    17461 ctggtcttga gatgagccag aacagcgaga gatacagctg gacagcagag gaagttgata
    17521 caaaacttca tcagatcatg actggtatcc atgatggttc cgcagcagca gctgagaaat
    17581 acggcttagg ctacaacctg gtagctggtg ctaacatcgt tggtttccag aaagttgctg
    17641 acgctatgat ggctcagggt atctgctggt aatcagtacc aacaatcgtt acataaagcg
    17701 gttatctaag taagaggggc tgctgcatta agcggggtaa tgcctggcat caggcgccgt
    17761 ttaaggcagc ggcccttatt taaaccagac aggctgtcag gcctgcctga aatcgaaagg
    17821 agataaaatt cactatgaag tgtcttatta ttgataaggt atatgcaggc attgcagaag
    17881 aactgggaaa atacatggag gtaaagacag cagacaatct gccgtcctcc aaggatcagg
    17941 ttctcgctga gatcggagat gtagacgttc tgatcatgcg cgtggatccg aagattgaca
    18001 aggatatcat cgacgcagct aagaacttaa agatcatcgg cgtttgctcc gttggcttaa
    18061 accatatcga tatggattac gctaaggaga agggaatcca gattttcaac gctcctggct
    18121 taaacgcaaa tgcagttgca gagcttacca tttccaagat gcttgacatc tcccgtggaa
    18181 ccatgacagc taacacagac gttaaggtta agcacgagtg ggataagtac aagttcgttg
    18241 gccgcgagct tcgcggaaag acactgggcg ttatgggctt tggccgtatc ggacgccgcg
    18301 taggcgagct gggacgcgct tttggcatga cagttgttgc ttacgatcca ttcttaaagg
    18361 ctgaagactt tgagaaggag cacgcaacag gcatgagcat cgacgagctc ttaaaggctg
    18421 ctgatttcgt atccatccac gtgccgttaa caccagagac aaaggatctg ttcaatgcta
    18481 aatccatcgc tgagatgaag gatgacgcag ttgttctcaa catgagccgc ggcggaatcg
    18541 taaacgagaa ggatatgtac gaggcattaa aggcaggcaa gatcggcgga tacgcaacag
    18601 acgttatgga gaacgagctg gcaggcagcg gcctgacagg aaacgacacc tttgcaagcc
    18661 cgctgttcga gtgcgataac ttcatcgttt ccccgcacat cggagcacag tctgtagacg
    18721 cttccaagga tatcggtatc catatcacag ctaaggtaaa agaggcactt ggcctgtaat
    18781 caaagataat aaagtattgc attaaggcgg gattcgcgaa ggcgtgtccc gccttttcag
    18841 atccctgcgg cagaagagag gacagcacaa atctgccgca gacgccttac gatataaaaa
    18901 gtagtgtatt tccccttttc gcgaatctcc caagaataaa acgcagtatt ttgtcacttt
    18961 ccacgaactc cccctgggaa taaaacatcg tttccggtga cttcaagtgg aacaagacgg
    19021 tttatgtgag aagtgctata aagaataggt tatatcgcaa ataaaaatgt aaaaaactga
    19081 tgaaaacttc gttgaaattt caccctaact cagttgaaat ttgtatgttt ttttgccaga
    19141 attgtcttta taattatgaa tattagataa gctgaggata gtttgagaag gaaaaaaagt
    19201 atttttggct tatcagaaag acagaattca gccctttcag cggctgtttc tgtagcaaag
    19261 gaactgtaaa cgaaaggcac cgtttaaaac ggtgaaatca gggggaagtt tttatgaaga
    19321 aaaaaacgaa acgcgtagtg ccggctctgc tgagcctggt catggcggta tcgtctgttc
    19381 ccggcccagc ctacggcgct ccgctggtta cgctcttttc ctcagcggaa gacgacacgc
    19441 agatggtctc agacgcggag acagtatttg tgaatttcta tgacggatcg gttcgttctc
    19501 aggacttcaa cagcaactgg aagtttttcc tgggaaatgc cggcaatgca caggaggtca
    19561 atttcgacga ctccaagtgg aaggcagtga gtctgcccca tgactacagc atcgagcagg
    19621 attactctcc aaatatggag gcggagagcg gctatcttcc gggaggaacc ggatggtaca
    19681 gaaagaattt cacagttccg aaggaagctg ccacaaagca ggtccgcgtg gatttcgacg
    19741 gcgtgtacat gaacgccact gtgtatatta atggacatca ggtgggaacc catccttatg
    19801 gatactcgcc gttttccttt gacctgactc cgtatctgaa ctatggcgga gataatgtaa
    19861 tcgctgtaaa ggtagatcac aagactccgt ccagccgctg gtattcagga agcggtattt
    19921 acagagatgt gaagctgacc atcacgccta tggtacacga ggcgctgcac ggaacgaagg
    19981 tggagcttcc gaatctggag tccaatcaga gcaatccttc cgtccatgtg gagactgccg
    20041 ttcagaacga gtccggatct gaggctgagg tcacagtatc tcatcggatt taccggaagg
    20101 acgatgacag caagactccg attggcgaga ttacggcaga tccggttaag gtagccagcg
    20161 gagcgactgt gacggtggag agcgatatga ctgcgtccaa tcccgatctc tggactctgg
    20221 atgatccgga tccgcagctt tacgtgatgg agacaaccgt cagcacagga acgactacag
    20281 acgtaacgac ctctgatttc ggtttccgtt actttgattt tgacagcagt actggtttct
    20341 ccctgaacgg aaagaacatg aagctgaagg gcgtttgtat gcaccacgat cagggctctc
    20401 tgggcgcgga ggcctgggac agagccattg agcgtcaggt agagattctg aaggacatgg
    20461 gctgtaacgc catccgtgtg acgcacaacc cggcggctca ggatctgatc gatatctgca
    20521 atgagaaggg aatgcttgtc attgaggaga tgttcgacgg ctggcatggt tctaaaaatg
    20581 gaaataatga agattatgcc aagtggtatg gaaagaatat cgaggacggc aacctgatta
    20641 tcggacagga agagggcggc atgacatggg ctgagttcga tatgaagtct gtcatccgca
    20701 gagactggaa cgctccaagc gtgatctcct ggtccctggg caacgaggtc atggagggaa
    20761 ttggtattgg agttggcgat tacccgaatc aggctcagaa gctgattgcc tgggcggtgg
    20821 agacagacga tacaagacct gtaaccactg gggataataa gctgaagagc ggtctggcac
    20881 agtcccagca gatcggcgag aagctggccg ctgcggatgg tctggtaggc tttaactaca
    20941 ctgccttaaa cggcagcaac accttatccg attaccatgc aaagcatccg gactggaata
    21001 tctacggctc agagacagcc tcctccatta acagcagagg cgtttacaag ccgtctctct
    21061 acgacagaca gctgacagcc tacgacgagt ctaaagtagg atggggacat tttgccagcg
    21121 acgcctggta cactaccatc cagaaggact tcgtggcagg agagtttgtc tggacaggct
    21181 ttgactacat cggagagccg accaactgga acggcgtggg atctggcgca gtgggaacat
    21241 ggccatcccc gaagaactcc tactttggaa ttattgacac agcaggactt ccgaaggaca
    21301 gctactatct gtaccagagc ttatggaatg agtatgagaa tactcttcac attctcccgg
    21361 catggaacgg cgatgtaata gagaaggatg atcagggaaa tgtaaaggta gtggtttact
    21421 cagacgctcc gactgtagat cttttcttca ctccggaagg aggacaggaa acttcactgg
    21481 gaagcaagac catgactgag aagcacagcc aggcagatga cggcagcgaa ggcctctata
    21541 cttatcagat gtatgagggc gacgacaagg acaacacagc ccataagaac ctgtaccgca
    21601 cctggaaggt tccttatcag gatggaacgc tgcgggcagt ggcgaaggac gcttccggcc
    21661 gtgagatttc caatacagtg ggaagaaatg tagttaagac agccggaaag gccgccaaga
    21721 tcgaggcgga ggctgacaga gacagaattg acgccgacgg agacgatctc agctacatta
    21781 cagtaacgat tacagacgag aatggaacga tggttccgga cgcagacaac cgtgtgaagt
    21841 tcaccgtgga gggcgacgga aagctggtag gccttgacaa cggctggact acagaccatg
    21901 attcctatca ggcagacaac cgcagagcgt tcaacggaca gctggtagcg attgtacagt
    21961 ccacagagga ggaaggttcc ttcacactga aggcagaggc cgatggactg aaaggatgcg
    22021 aggtcacagt agacacagat gcggttgaga gcggagagac cgatccaggc gccgacaaca
    22081 tggtggcaag ctacgaaatt tccaagaact actatgtaaa ggtaggctac gagccggtgc
    22141 ttccggagac actgccggtt acatacacag acggaacgac agcagagctt tccgttgtgt
    22201 gggataccat tccgcaggac aagctggacg aggaaggaag cttcctgtta agcggcgata
    22261 tggagggaac caaggtttcc gtcagcatca atatgatcag ccagattgcg gcgatcttaa
    22321 actactccac aaccgtgcat ctgggcgagg ctccgcttct gccggagtca agacagctgg
    22381 tatctgagga tggagagatc ttaaatatcg cccttccggt tgagtgggac gagcgtccgg
    22441 ctgacgacta caaggaagag ggcatcgtaa cggtgaacgg aaccgtttcc gtcttcggag
    22501 agccgatgga tgtgacagct tccgtgcggg ttcagaagga gaaagcggtt atcacagaca
    22561 atgtgggaac caaggccaag gtcagccaga cagtaggaac tccgtctgat gcactgagcg
    22621 caatcaacga cggctccacg aagagtgtgg ataatccttc cagccccaat aactccagat
    22681 ggagcaactg ggactatacg aagaagactc agaatgatcc gccggcagag cttcagtttg
    22741 tctttgacac acaggagaca ctgggacaga ttaagattta ctttgtaagg gataacggct
    22801 cactccgatt cccggatcct ggcattacga agatttacgt ttccaacgat atgaagcagt
    22861 ggacagagct tcacacactg ggagtgaagg agacaattcc ggataaggaa acctccagca
    22921 tggtaaaatg ctatacctac gactttgctc cactgggagc tacctacctg aagctggaaa
    22981 tccacaataa caaagcaggc agcgcgggtg ctgcaggcgc agagatgccg accacaggaa
    23041 tcacagaggt agagctttac cgctctgagg gacgcttcac agtcaacagc tctacggctc
    23101 tcagcagcct gaccttaaac ggcgtgaaag ctccggagtc tgctctgaag gcaggcgagt
    23161 acaacactcc gatgagcgtt gtggaggagt tacaggcagt cagcgaggag aatgcggcta
    23221 tcaccgtact tccagctgca gacggacagg tgaaaattct cttagagtca gaggatcact
    23281 ctaagatgga tgagtttatc attcatctgg agcaggattc cacaggaagt gcagacgatg
    23341 attctatgga ttatccggta aaggatatga aggtaaccgt tggaaatgag catggaactg
    23401 ataagaaaga gaatgccctg gacaacaact acggcacagt atggcataca gactggaata
    23461 atgtaactcc tgtcgaaaaa cgctggattc agctggaact cgacaaagag accaacattg
    23521 acgcgctgcg ttactattcc agaaatgacg gtcctaacgg acgcgttaac aaatataaag
    23581 tggaggtaag ctccgacgga aaagactgga aaacagtttc cacaggaaat tggaaaaatg
    23641 aaggaggctg gaagctggcg gcctttgagg agccagtaaa ggctaaattt gtcaagctga
    23701 ctggtgtgga gacatatgga aatactgcca atatgtttat gagcgccgcc gaggtgagag
    23761 tccggacagc cagagagaca acaaaactga cagaggacaa tgtgactctt tcagaggata
    23821 cctttatcat ggacgaggat cagactccgg tgaagccgga agtatctgtt tccattgacg
    23881 gaaaagccct gagatacggt attgattaca cggttaatta tgagaacaat gataagccgg
    23941 gaatcggaac tgtgattgta aagggaatca tggactactc aggcgttatc cgcctggagt
    24001 tccacatcgt gggcagcaat acccagaatg tgacagttct ggatggaacc atcacaaagc
    24061 tggatgatca ggagctggaa ggccagactc agatcgaggc agagagcgga agaatcgtta
    24121 cagtgaaggc agacgtaaag gatggaatgg agtttgacca ctggagaaca gctccggcca
    24181 acctgttaag caaagaggat atgaagaagg aagaggtttc cttcatcatt cctgaaagcg
    24241 gaagccgtct gcacgcagta tacagagaag agggagaaga caaactgtct gaagaagctt
    24301 acacgacagc agagccgtca aactggttcg cattcggcga cgaaagcgac atggaggcgc
    24361 tgcttgaggc agctctgaca gacagcgacg aggtaattct tcagaaaggc ggatccgcag
    24421 aggttaagat gaacctggag cgctctaaga aagaaccgag caagatggat atcctgaaga
    24481 gctatgagct tctggcaagt ccgtctgacg cagagaagga agaggatgac gacgataaga
    24541 acgtaacctc caaggcaact gcctccaatg cagaaaagag cgagacagtg aaagcaagcg
    24601 catccgacgc agaggaaaca ctgaatccga gagatatttt gaaggacgag gtactttctc
    24661 cgttaaaggc agtaaaagaa gaggctggtc ttaacgatga cgaggaagct gccagaacga
    24721 caaagattgc attctggatt cggacaacag ctgaaaaggt agtgacaaac agcgctggaa
    24781 atccaaccag aacacagctg gtagatccaa agcttccgga ggttcagatt acagcggagc
    24841 ttccgaagga cgacagaagg atggaagact accaggtaat gcgctacgag tacagcgagg
    24901 acggcacaag cgtatcagtg gtaagctgcg aggtagaggg aaataacctg atctttgacg
    24961 cagcgccgga cggcgtttac gcagtcatgt atacacagtg cttcgacgta atcttcgagg
    25021 actacgacaa gacagttctg agcaaacaga gagttgccta tggcaatgca gctgaggctc
    25081 cggaggatcc gaagcgcgag ggctacacct ttgcaggctg gaacaaggac tttgactatg
    25141 taacttctga catgagaatc cgcgctgtgt atgaggaagg cgaggagaag ccggaggtaa
    25201 ataagaaccg tctggaggcc aagattgagg agatccagag aaagatggac gctctcgatg
    25261 aggacgatta cacaagctcc agctggagca agctggagga cgctcttgac gaggccatcg
    25321 ccgtactgga ggatgaggac gcgactcaga ctcaggtcaa taaggcggca gagaagctgg
    25381 acaaggccta taaggcgtta aagagaatag gcggcggaag cagccattcc ggcggttccg
    25441 gcggaagcgg ccattcctcc agccgtccgc tctacggaaa cagcaagccg cagccgttag
    25501 acggaggagc ctatgtgaca aacggaacat ggacgaacgt tcaggacggc tggaccttca
    25561 caaaagagaa cggagagaag gcagtttcct gctggatcta cactctctgg ggagattcct
    25621 atgagtggta ttacttcaat gcagaaggaa agatggcgac tggatgggtt gaggctgacg
    25681 gacagacctt ctatctgaat cctgtatctg acggtacaag aggaaagatg atgacaggct
    25741 ggcagctgat tgacggaaaa tactactact tcaacaccgt atccgacggc acaagaggag
    25801 ctctctacag aaacagaacg actcccgacg gataccaggt aggagcagac ggagtctgga
    25861 tccagtaaaa ggaatatgaa aatctaaaac agggcagaga gaaatggttt cgcggcttcg
    25921 actgaaagcc gccagaaact gtttcctctg cccgttttgt tgtgttttgg gaaagaaatg
    25981 catatttttt acaggaaaac tatagaaata tcagatagga tatggttaaa tagatataga
    26041 atttcagaat caggaggaaa gatgtatgtc agaagaaaga ttaaatgaaa atatggagaa
    26101 tatggagacc atggccgatt acgagaagga gatcgaggaa tcctttaaga aaaatgagga
    26161 cactcctgta tgggaaaagt ttgccaaact gatggaggag aagactccgc ttcaggtgga
    26221 gatcgccgag gtggtaaacg gcggcgtaac cgcttatgtg gatggtatca gaggctttat
    26281 cccggcttcc aagctggccg cttcctatgt ggagaacctg gaggagtggg ttggaaagac
    26341 cattgacgtg ctggtgatca ctgtggaaga ggagagaaag aagctggttc tgtccggacg
    26401 tgagctggcc agagagaagg agcaggagga gaagaaaaag agagtggagc agtgccaggt
    26461 aggcgcggtg atggaaggaa ctgtggagac catcaaggac tacggcgctt ttgtgagact
    26521 ggagaacgga ctgtcaggcc tggttcacgt atcccgcatc agcagccaga gagtgaagca
    26581 cccgggcgca gttttaaagg aaggtcagac tgttaaggtg aagattgtgg gaattaagga
    26641 cggcaagctg agcctcagca tccgcgacgc acaggagaag gaggaagagg agcttcagca
    26701 ggaggagttt ttcgactacc acgagaatgg ccaggccgct accagccttg gttctctgtt
    26761 aaagggactg aaattttagt tagatatttg gctcagccag cgcgaaagct tcagtgaaag
    26821 gaggccgttc atagtgaata ttccaaagag ctttaaccag atggatcagt ggaaggccgt
    26881 gatgtttttg tataactccg cgctgaagga gatcaataca aagatcgaga ttctgaacaa
    26941 tgaatttgtt cacatttatt cctacaatcc gattgaacat attaaatcca gactgaagac
    27001 gccggaaagc attgtcaaaa agctgaaaag cgacggcaga gaggtgacga tccccaacat
    27061 gatcgatcac ctcagcgata ttgccggaat caggattatc tgttccttca cttcggacat
    27121 ctacaggatt gccgacatga ttgccaggca gtcggacgtg acggtgctgt atgtgaagga
    27181 ctacattaaa aatcccaagc ccaacgggta taagagctac cacatggtgg tgacgatccc
    27241 catttacctg agcgaggggc cggtggacac caaggtggag attcagatcc gcacggtggc
    27301 catggatttc tgggccagcc tggagcacaa gatctactat aaattcgaag gaaacgcccc
    27361 tgattttctg gagaaggagc tgaaagcctg tgccgacatg gtggatctgc tggatgcgaa
    27421 gatgttttcc ctcaacgagg cgattatgaa gatcagcgcc gagcagaggc tgaaagagga
    27481 agaggagttc aggcgctcca gagagactca ggaatgatca taaaaaacgg agaagaagaa
    27541 catgaaaatt gtactgcaga gagtaaccca ggccagcgtg acagtggatg ggcaggtaat
    27601 tggaaagata ggacagggat ttctggtcct gctgggagtg tgcgatacag acacagaggc
    27661 cattgccgac aagatggtgg acaaactgtg caagctcaga attttccagg atgaccaggg
    27721 gaaaaccaat ctctccctgg cagacgtggg aggagagctt ctggtagtca gccagtttac
    27781 cctgtacgca gactgcagaa agggcaacag gcccagcttt gtcaaggcgg gagctcccgg
    27841 catggccaac cggctctacg agtatgtggt agagaaatgc aaaggttatg taaaccgagt
    27901 ggagcacggc gagttcggcg ccgacatgaa ggtggagctg ttaaacgacg gcccgtttac
    27961 tctagtactt gacagcgagg aaatctgccg gtaggaaaag aacggatgaa gcctgggacg
    28021 aagcgtttca ggcccgccgc agaacagaca gaagcgatat aagagcgatc tcagaatgaa
    28081 aagaatcaga tgagatacgg aaaggagcat gacacatgga tgagagcgta aaggagctgc
    28141 agaagcagct gacatgggaa ttcccgcaca ttgcaaagga ggcgccggat cagacgaagg
    28201 aggcggctga atactgcgag ggatacaagg cgtttttaaa taaggccaag acagagagag
    28261 aatttgtggc tgaggcagtg agaattctgt ctgagaacgg ctaccaggaa tatgaaatcg
    28321 gaaagaagta cgagacaggc gataaggttt actttatcaa ccggaaaaag gccctgatta
    28381 tgactacctt cggctgcagg ccattagagg agggcatccg attaaacatt gcccacatcg
    28441 actccccgcg ccttgactta aagcccaatc cactttatga gaagacggat ctggccttct
    28501 taaagactca ctactacggc ggaatccgca agtaccagtg ggcgaccatc ccgttagcca
    28561 tgcacggagt ggtgattaca aaggacggaa cggcagtgga catctgcatc ggcgaggacg
    28621 agggcgatcc ggtattctgc gtgaccgatc tgcttcctca tctggctgca gagcagaatg
    28681 agagaaagct gaaggacgga atcaagggcg aggagctgaa cgtgctggta ggctctattc
    28741 cgtatgcagg cgaggagatc aaggagccgg tgaagcttct ggttctcaag ttgttaaacg
    28801 agaagtacgg catgacggag aaggatttca ccagagcgga gatcgagatg gttccggctg
    28861 tgaaggccac agatgtggga ctggacagaa gcctggtagg cgcttacgga caggacgaca
    28921 aggtgtgcgc ttacactgcc atgacagccg agatggccac agagaagccg gagtacacca
    28981 cagtgactgt gctggctgac aaggaggaga tcggatccgt aggaaacaca ggactggatt
    29041 ctgatttcag ccttcattac atcgagtatc tggcagacgc ggcaggcgcg gacgtaaaga
    29101 cggtgctgag aaattccatc tgcctttcct ccgatgtaaa cgccgcctac gacccgacgt
    29161 ttgccagcgt ttacgaggag aagaactcct gctatgtaaa taaaggctgc gtactcacca
    29221 agtatacggg agccagagga aagtccggca gcaacgacgc cagcgcggag accatggcca
    29281 aggtcatcga cattatggac cgggaaggcg tgtactggca gatcggagag ctgggagccg
    29341 tagacgtggg cggcggcgga accgttgcct gctatgtggc taagatggat gtggacgtag
    29401 tggatctggg agtgccgatt ctggctatgc acgcgccgtt cgagctggct tccaagttgg
    29461 acatttacaa cacctacaag gcgtttaagg cattctataa ataaatctta aaaaacagta
    29521 aaaatcggaa aaactctttt ttatcgcagt attttgtgat attatgtgtt ttatactttt
    29581 cagaacgtgt ttggagatac aggttatttc caaacacgtt tttaaagaaa agtggcaaaa
    29641 caaaaggcgg aacgtccgtc ttttcaaaca gtaaaaagag agtaagagga caggtaaatg
    29701 aggaaatttg taaaggcagg actggcagga ctcgcggctc tgatgcttat gacaggctgc
    29761 ggcgcgaagg agcagacggc gactccgtct gatgcggaga gtaaggcgga aggcggcgaa
    29821 gaggcttccg aagagtatat tgccgaggga agcattaccc tgggagagta taagaatctt
    29881 ccggttacag tggtaaatcc tactatttcc gacgaggagc tgcagggcag gattgacacg
    29941 gttctcggag gctatgccac ctgggatgca gtggatcggg aggcagcgga cggagacaga
    30001 gtcaagattg attacaaggg cttaaaggac ggagaggcct tcgagggagg cacggctgag
    30061 ggctatacgc tggtgctggg atccaacacc tttatcgacg gctttgagga aggcctcatc
    30121 ggcgtgaagg ccggagagga gagagacctg aatcttacct tcccggagga ctaccaggcc
    30181 gaggatctgg ccggacagga cgtggtattt gaggtgaaga tccacgaggt agcggaaaag
    30241 catgtgccgg agctgaccga cgagttcgta gctgagaatt tcccggagct tggaactgta
    30301 gacgcctaca aggcagattt aaagcagcag atgttagacg ccaaaaccat gcagagcgaa
    30361 cagcagagag acgcggagct tctggctgct gtggtggaga attctgagat cgcctgcgcc
    30421 acagacgagg tgaatgaggt gtacgaccag cagattcagt actacacctc tatggcaggc
    30481 atgtacggca tgggactggc cgattacgcc gctatgatgg gcatggatga ggatggtttc
    30541 cgcacagagg tgagaaagat gtccgagcag acagtaaagc agcagatggc cctgatggag
    30601 attgcaaaga aggagaagct gaccgtcgag gacgctgaca gagaagctct ggcagaggag
    30661 tataaggacg cctacgagag cgtggacgac atgatcgaga aggccggagc tgagaacgtg
    30721 gacaatgcca ttctctacga taaggcaatc caggtggttg tggacaacgc tgacgttacg
    30781 aatgtagacg gactggcagt agccgagtag cttaccaagg atggaggttt taggaaatgc
    30841 agatgttata tgacagaatc cgcagggacg gagtggtgag agctggaaac gtgctgaagg
    30901 tagaccgctt cctgaatcat cagatggata tcgagctgtt taaggagatt ggaaaggaat
    30961 tcaagcgccg ttttgccgat gtggaggtca ataagattct gacaatcgag gcatccggca
    31021 ttggaatcgc ctgcattgta gcccagtact tcaacgtgcc ggtggtattt gccaagaaga
    31081 ccaagacgaa gaatatcgcg ggcgacgtat ataccacgaa ggtagaatcc tttactcatg
    31141 gaacggtata tgacattatc gtgtccaagg agttcctggg aaaaggggac aaggtgcttg
    31201 tcatcgacga tttcctggct aagggaaagg ccctggacgg cctgacgaca ctgatccaga
    31261 actcgggagc cgagctggtg ggagcaggaa ttgttatcga gaagggcttc cagtgcggcg
    31321 gagacattat ccgccagaag ggaatccgcc tggagtctct ggccattgtg gacagcatgg
    31381 acgagacgac gggggagatc gtattccgcg gcgaggagaa acaggcttaa cgacaggaaa
    31441 tacagcgagg aaggcataaa ggaattacaa agtgggaaac agaaaagcgc ttttttttga
    31501 tattgacgga acgctgctca gcgagggaag agacagaaaa gtaccggaga gcgccagaaa
    31561 ggctctcctg caggcgagag aaaagggcca cctggtattt gtgaataccg gaagaacctg
    31621 gtgcgagacg aaggaggtca ggcatctgat tgacgcagac ggctggctct gcggctgcgg
    31681 cacctatctc atggcagagg gagaagtgct ttacgactgg agaatctccc cggaacgggg
    31741 ggatcagctg ataaagctga tacgggactg cggcatggac ggagtgttag agggcgtgga
    31801 ggcctgctat atgcagaagg ccccgtctcc gaccagggca gtggagcagt gcagacagga
    31861 tttctcagct ctggggattg tctcagagaa aacctgggac gacgaggata tcagcttctc
    31921 aaaattttgt ctcgtgacag atgaaaacag ctgtctggag cggtttaagg aagaaaccag
    31981 ggaggatctg gaggtgattg accggggaag cgcctttgtg gaggtggttc ccagagggca
    32041 ctcaaaggcg gctgccattg agagaatcct tggccggtat gggcttgccc tggaggacgc
    32101 ctgggtattc ggcgacagca tgaacgatct gtccatgttt cagtatgccc ggaatgctgt
    32161 gctgatgggc aggcacgaca aagaactgga gccctacgcg tcctttataa cgaagacagt
    32221 ggaggaggat ggaatcgcct tcgccatgga gaagttcgga ttaatttaat cagacctgct
    32281 ttggaagaag aaacgtatag aaagggaggg atgccagcgt gatcggatta agatgacgct
    32341 gggatccctc ccttttttga tgcttttgaa ggcggatatc tggttaccac ctcttagaca
    32401 cgatgatttc ccccttctta atcacagtct ccacctgatt gactgccgtg tggtagggca
    32461 ggtaggcgat agaagggtat ttcataatca ggatatcggc ctgcttgccc tcctcgatgc
    32521 ttccgatggt gtcggcgcgt cctacggcag ccgctccgtt gatagtcagg gcggtgatta
    32581 cctcctcgat ggacatgttc atgtagatac agcccagggc aatcaggaga gggatggaat
    32641 tcgtaaagca gctgccggga tttaagtcag aggccagagc cacggcgcag ccgctgtcga
    32701 tcatttttct ggcaggagcg tactcttcct ttaaacagaa ggcggtggca ggcagaagcg
    32761 tgctgatgac gcctgcttca gccatctggc ggatgccctc gtcggaggcc ttcagcaggt
    32821 gatccgcaga gacggctccc gccctggccg ccagctctcc tccgcctaag gggtacattt
    32881 catctgcgtg gattttcagc ctgaagccca gtttctttgc ctggtttaag tagtattcag
    32941 aatcctcaat ggagaagaca tttttctcac agaagatatc ggcaaattct gccaggtttt
    33001 ctttcttcgc cagaggcatc acctgagtca gcatatagtc taaaaattcc cgctctctgc
    33061 ccttatattc cgggagcacg ctgtgggggc ccaggaaggt ggaaaccacg tctaagggat
    33121 ggcgtctgtc cagctctttc atgacgcgga gctgttttaa ttctgtctcg cagtccatgc
    33181 cgtagccgct ttttccctct acggtagtga ctccgaattc tgccatccgg ttgagacgat
    33241 ccataccggc ggcaatgaga tcttcctcag aagcttcttt cgtagggcgg atggtggcgt
    33301 tgatgccgcc tccccgttcc atgatagaca tgtagctgtc tcccttcagc cgccaggaga
    33361 actcgtctgc ccggaagccg ccgaagataa agtgggtgtg ggagtcaaca aagccgggaa
    33421 ggaccgtttt tccccatgcg tttaaagtag tggcgggctg gccgtttagc tctgtgtcgg
    33481 ccggttcagc cgcctgggag gatatagaag ccgtctcgtg atgcagagcg tctgcctgct
    33541 ttggatcaag gcccagccgc tgatccagct ctttcgtcgt ccccaccgcc tcgatgcggc
    33601 cgtcggaaag aagcactgcg ccgtcctcaa tcaggccgat atcggccatc tccctgccgc
    33661 gcctgggagc cttgccccgg caggtaacca gttcggaggc gtggcggatg tataattttt
    33721 tcatagataa aatcccttct gccaagttta ctgcctgttc accgcgttct ggtaagcctt
    33781 ctcaatcagc tcgtcgtctg cgatataagg catggtaatg acgtcgctgc cttttctcat
    33841 ctggttatat tcagctaccg tctcgatgga gtgctcgttt ctggcccagt ttcttctgga
    33901 gacgcctacc atggtatccc acgggatggc ctcccggatg atggcgtccg tctcagctgt
    33961 gccgtccagc acaaggccga agccgccgtt gatggccttt ccaatgccag tgccgccgcc
    34021 gttgtggagg gcaattaagc tcatgcccct ggctgcgttt ccggcatagc actgcaccgc
    34081 catgtcggcc gtcatgttgg atccgtcata gatattggag gtctcacggt aaggagaatc
    34141 tgtgccgccg gtgtcgtggt ggtcgcggcc cagcataacc ggcccgattt cgccgtttcg
    34201 caccatctcg ttgaacttca gggcaatgtc ccttcttccg aaggcgtcct ggtagagaat
    34261 acggcactgg gttcccacta ccagctgatt cttctctgcg tcccggatcc agatccagtt
    34321 atccttatcc tgcggcctgc ggttcggatt gatgatttcc atagccgcgt ggtcggtctt
    34381 taccagatcc tcgtgctttc ctgacagaca gcaccagcgg aaggggccgt agccgtagtc
    34441 gaagagctca ggccccataa tatcctccac ataggacggg aaaatgaagc cttcgctggt
    34501 gtcggttccg tttttggcga tatcctttgc cccggcatca aagactgcct tcataaagga
    34561 gttgccatag tcgaagaagt aagcgcctct ctttaccagt tctttaatca ggtggaaatg
    34621 cttaatcaga gacgcgttga caagctctgc gaagcgctcc ttgtcgtggg ccagcatctc
    34681 agttctctcc tcaaaggtga ggccctgcgg gcagtagccg ccgtcgtaag gcacatggca
    34741 gctggtctga tcggagagca gctcgatttt catttcgtga tccaccgcat actgcaggag
    34801 atctacgata tttccgtggt atgcgatgga aatagtctct tttcgtttca tataatcagc
    34861 tgccagacgg aaggcctcct cggcgctctc cgtgatcagg ctgacccagc cctgactgtg
    34921 tcttgtctca atgcgggagt aatccacctc agcgataatg cccacgcctc cggcgatctc
    34981 aatggcctta ggctgagcgc cgctcatgcc gcccagaccg ctggtgacga acagatggcc
    35041 ggccaggtct ccgtcgtggg gaacgcccag gaatttccgg cctgcgttta aaatcgtgtt
    35101 gaaggtgccg tggacaatgc cctgaggccc gatgtacatc catcctccgg cagtcatctg
    35161 gccgtaggag gaacagccca tggcggtggc cttagcccag gcctctggat tgtctccctc
    35221 tccgaccata aggccgtttg tgattacgac tctggggctg gacttgtggg atttgaacag
    35281 gcccagcgga tggccggaca tgaccaccag agtctgctcg tctgtcagaa tttccagata
    35341 cttcttaatt aactgatact gcatccagtt ctggcacacc tgtcccgtct cgccgtaggt
    35401 aaccagctcg taggggtaga gagccacgtc atgatttaag ttgttgtcga tcataacctg
    35461 gaacgctttt ccttggacgc agtttccctt atactcgtca atgggctttc cgtaaattct
    35521 ctccttgggc ataaagcggt agccgtagat gcgtcccctt gtcaaaagct cctccataaa
    35581 ttccggggcc agatctttgt gaagctcctc cggcacatag cggagggcat ttttgactgc
    35641 cagcttgatt tcacgttcat ttaaggtcag ctctctcatg ggagcccggc ggataccctc
    35701 cttgaataca ggatattctg gaaggacagg atccagtttg attgtcatgg ctgcaccgat
    35761 ctctttgttg ttcatatatc gcaccttcct tttaaaatca ttgatagctt tattatagac
    35821 gcccacagtc taaaaaacgt caaaaacgcc gggggttcct tttattgacc aatgatccca
    35881 agtaaggtat acttaaggaa gactgaagca ggcagatgtt ccggggggct ggacgtctgc
    35941 tctgcggcaa ctaggagagg aaaatggaag aaattgcagt acagctgttt gggattccgg
    36001 aaatacggct gggagatgaa aaaatccgct ttccttataa gaaagcggag gcatttttct
    36061 actacctgtg cgtgaggaag aaagtcagcc gggaccaggt gatctgtctt ctctggggag
    36121 atgaggacga gacttcaggg aagaaaaagc tgcgggacgc cgtgtaccag gtcaagcggc
    36181 tgctgggaaa ggatctgctt ttgacaggcg gccatacgga aattgagctg aatccgcagg
    36241 cgcctctcag aacggactgg gaaaagcagg aagagccgga gaacgaaggg gaatttttag
    36301 atcattttta tatcaaaaat tgttatgaat ttgaggaatg ggcggaagag atcagaaccc
    36361 gcatccgcaa acgccgggca gaggaggcca gacgccggat ggagaaggcg gctgtagaga
    36421 aagacgacgc cagccttcaa aaatacagca atttccttct ggcggaggat ccgtacaatg
    36481 aggagctgta tttcgagacg atgagtctgt atgcggaaaa tggcagttac acgatggcta
    36541 tccgcctgta caacgatttg aaacggcggc tgtccagaga tctttcagag gagccgtcca
    36601 aggggctgaa agagttgttt cagcgcattt ataacatgaa ggaaacggtg caggcaggag
    36661 aagccgggct tacgctttcc tttgtgggca gaaaaagaga gctttatcag ctcagcggtt
    36721 ttctgagcgg acgggaagga gcggaaagcg tcctggcagt ctgcggggag agcggttccg
    36781 gaaaaacggc tttcttagag cagggaatcc gtctggcgtc aggagacgga tttactgtgt
    36841 taaaaaccgc ctgctataag cagggggagg agttctactt aagcccgtgg aacgatattt
    36901 ttcaggagct ttaccagctt tcggagcggg aaaaccaggc gggcggagca ggtgagattc
    36961 tggaacagtt cttaaacggc gcaaaggcag aagagggaaa ggcttccagg atgacctacc
    37021 ccatggtaga gaagatggcc ctggatctgc ttcaggcttt gtccaagagg cggcggatcc
    37081 tcctggtgtt cgacgacatc cagtggatgg attccatgag cggacagctt ttaaaccgag
    37141 ttcttctgcg ccttggaagg gaacggcttc tcctcctgtg cagcatgagc agagagggag
    37201 agggaaggac tctggaatcc ttagagccgc tgctcttgaa ggatcaggtg gcaatcctgc
    37261 gcctggaacc gtttaccagg gaggagacag acgagctgat ccggaaaacc cttccggatc
    37321 tggcgtcgga ggaggagaag aaggcggaga tctaccgggc cacagacggg aacgcgtttt
    37381 tcctgcggga gcttctgact ctgatccggg aaaaaggata tactctggaa aaatcaaaga
    37441 agacaaacta tgtgattcag gccaggcttt ccggcctgtc cagacaagag agagagacgc
    37501 tgggggctat ggcggttttt cccgggaaaa tccaggtgga ggatctggaa ctgcttctgc
    37561 ccgatacaga ccgcctgtct cttttgcgtc tgctggaatc cctccaggaa cgctttctga
    37621 ttcgtgaggt gctgactggg tggaatgtcc agtatgagtt tgtccaccgg gcgtttcagg
    37681 aatacgtctg cgagcagcag agcaggggaa agacgcagct gtaccatcag attctggcca
    37741 gacattatga ggagaaggct cttcagagca gggagaccac gctgtttccc caggtaattt
    37801 accattacga gggctgccac gacttgatca gggcctgctg gtacaaaatc gagtggatga
    37861 aggaatatta taccctgatc aatgaaaatt tcccggtgct tcactggcag gtggcggatc
    37921 tgtctgaggg cgtgggagtg atgccgcagg cagatgagat gataaggctt gctggggaga
    37981 ttatggatct ccagggaagc tcggagaaga tccggcggat gaagctggag atgaactaca
    38041 tcctgggacg ctatcacatt gcccagggag aatacagaca ggggcttttc cacattgagg
    38101 agggaatccg tctggcaaag gagctttcag ataccaggat gctgctgtcc tgcttcaggc
    38161 agcagatctt ctatggaatt caggtagaag atctggaacg ggtgaaaacc tatgtggaga
    38221 tgggcataga gaaggtgaaa gaaaacagcc cattacggga agcgttttta tctctggaat
    38281 gggagctgga acattcttcc ggacagacct tggaggagac tttaagggag cgtttgaagg
    38341 agagcagggg agacggcgcg ttgcaggatg acgatgtgaa agactgggag gaatacggca
    38401 cgtttctccg cctgaagggc tggtatctgc tccacagcca gacggattcc caggcagaga
    38461 ggacgctgtg ggcggccgct gatattttta aaggtctcgg atccggctgc gaacctggcc
    38521 gggccgcctg tctgagctat attggagaca gcatggacag acagggccgc tttttggagg
    38581 cagtgtcctt ctatgagcag gcaatagctc tggtggagaa aaatcccaga attaatggcc
    38641 tggggcagtt ctatgccagg gccggacagg ctctcttcat ggccggaaac acagagaagg
    38701 gccgggagta tctggagcag gcggaaaaac gcctgaagga aaacggctgt gtctggggcc
    38761 tggagcggac ggaggctctg ctgtgcctca taagcctttc agaaatgaat ttagaggagg
    38821 cagaacgtcg tttttatgag ggaatggagc tttcagaaaa aatcagaaat ccccagacgc
    38881 agaagctttt ggagacagcg cggcagaagc taaggaaaag aggagcgcag ctgcagaaga
    38941 gatttggcgc agacggcttt tcatagacgg ttttttgacg ctgaactctg tataatagag
    39001 ataacaaaca gaaatacata aaagagagag ggttgtttta tgaataaggt gctgattaca
    39061 ggagaagatt tgacgctgga tgagattgtc agcgtatgcc gcgggaacgc gcaggtggag
    39121 atttcccagg aggccaggga aaaggtacag gcgtccagac aggtggtgga cgatttaatt
    39181 gcagaggaga aggtagttta cggcattact actggatttg gcaaattcag cgacgtggtg
    39241 atttcccagg accagtgcaa agagctgcag aaaaacctga ttatcaccca cgcggtagga
    39301 gctggagatc cattctccag agacattgcc agaggcatta tgctgctgcg catcaataac
    39361 ctttccaagg gattttccgg aatccgcatg gaaacgcttc agaccatggc gtatatgctg
    39421 aacaagggag tgactccgat tatcccggaa aagggttctc tgggcgcttc cggcgatctg
    39481 gctcctcttt cccacatggt tctgccgatg atcggactgg gactggccga gtatcaggga
    39541 gaggtgcttc ctggaaaaga ggccatggac cgggccggaa ttccagtgat cgagctttca
    39601 gccaaggaag gcttggcgct gaacaacgga acgcaggcca tgacaagcgc aggctcttta
    39661 gcgctttatg acgccctgga tctgattaaa acagccgata tagccgccgc tttaagcttc
    39721 gaggcccaga acggtgtggt ggacgccctg gatccgagag ttcataaggt acgcccccac
    39781 agcggccaga tggctacggc cagaaatctc ctcgctctgc tggagggaag caaaaatacc
    39841 acgagacagg gacagatccg agtgcaggac gcctactctc tgcgttgctg cccgcagatt
    39901 cacggagcca gcaaggacgc tgtgcagtat gtgaaggata aggtggatat tgagatcaat
    39961 tccgtgacag ataacccgat tattttcaag gacgaccacg cgggaatctc cggaggaaac
    40021 ttccacggac agccgatggc tttaagcttt gacttcctgg gcatcgcaga gtctgagctg
    40081 gccaacgttt ccgagcgccg tatcgagcgc ctggtaaatc cggcttacag cggccttccg
    40141 gccttcttaa cgccaaacgg aggcgtgtgc tccggcttta tgattgttca gtattctgcc
    40201 gcagctctcg tatctgagaa caaggttctg gcccacccgg ccagcgtgga cagcattcct
    40261 tcctccgcag gccaggaaga ccacgtcagc atgggaacca ttgcggccag aaaagcagga
    40321 gagattggac gcaacgtgag aagagtcctt gccatggagc tgatggtagc ctgccagggc
    40381 attgacatga gaggaaataa gggccttgga aagggaaccc aggcagccta cgatctggtg
    40441 agaaaggcag tggctgccct ggaggacgac agagagctct acgacgatat caactactgc
    40501 gagaagatta ttgaggacgg aagcctgatc cgtgcggtgg aggctgctct gggcagggag
    40561 attgaggtgt aaaaagccga acggtcagcc tgagaagcag aaagaaaact gaataaataa
    40621 acggaataaa taatgggcta taaggcgctg taaagtcaga taaggacttt gcggcgcctt
    40681 tttcaatccc cagtgctaat actcccctcc cgggaatata ctgtacaagc atcaggaggg
    40741 aggcgaaaaa aggtgggaat ggagacggct gccgctgtag ggattattgc agtgctgacg
    40801 gcggttcagt ttaaaagcag gggaacggag tttggtattt atgtgatcct ggcggctggg
    40861 gttttgattt ttttctacag cgcggggaag ctgagaatta ttttggaggc agtcaggcag
    40921 atccaaagct gtattcagat gaatcaggcc tatctgacgg ccctgctgaa gatggcgggt
    40981 attacgtata ttgcggagct ggcttccggg ctgtgcaggg acgccggata ttcctcgatg
    41041 ggaactcaga tagaaatgtt tggaaagctg tctattctgg ctgtgagcgt cccgattgtg
    41101 ctggccctgt tcgagacgct ggaatccttt ttagaatagg aagagagaga aacgggaggg
    41161 gcggttatgt ccaggatagc gctgtgctta ggccttgctg ccgcgctttt tttctcatgt
    41221 ccctggaggg ctgcgggaga ggagagaggg ggagcgggag aatgggagga gaaaacgcgt
    41281 caggaagaca acggcgggga ggaggagctg tctgccctgg aaggcatgga gctggacttt
    41341 tcttctgtgg aagagctgct tggcagccgt aaacagggag aaggacgttt ttcgtttgaa
    41401 gagcttttaa aggccgtttt caggggggat atgaaagagg cgtgttccat ggcgtttcac
    41461 ggtatctcgg acagtctgtt ttcagagctg tccgccgggg ccggacagat ggcgaagatt
    41521 cttctcattg cattaacagg ggccgtattt acctgttttt ctgatatttt ttccggcgga
    41581 cagatttcgg aaacggcctt ttacgttacc tttctgcttt tattttctct gctggcatcc
    41641 agcttttatg agagcatcgc tgtggcggat caggcggtca gccaggcctt tgaattaatg
    41701 aaagccctga cgcctggtta ctttatgaca gtggcgttta caggaggaag cctgagcgcc
    41761 ggagccagct gcggctggat gcttttttcc atcactgcag cccagtggct gctctcgcac
    41821 ctgatttttc cagtgttcag agtttatatt ctgctggtcc tggcaggaca tctcacaaaa
    41881 gagggagtat tttccaggat gacagagggg atacggacag cggtagaatg gagtatgaaa
    41941 actctgacag gagctgtgct gggctttcat cttctgcagg gaatggtgct tccctatgcc
    42001 gacgcggtga aaaacgcttc tctgaaacgg atggtttcca tgattccagg acttgggcag
    42061 ggagccttca cagtttcgca gatggtgtta ggctctggaa ttttaattaa aaatacagtg
    42121 ggagccgggg cggcgctggc gcttttagct gtcacagcgg tgccgatgat aaagcttttt
    42181 gttttaatgc tcatgtatca tttgatggcc gcagcagcag agccaatctg cgataagcag
    42241 ctgacagcct gtatggccga tgtggggaaa ggccatcaga ttctgctgaa actggtgttt
    42301 acttccctcc ttcttctggt tgtatccatc ggtgtgatct gcatggcatc caacgcatca
    42361 tactatgcgg catagagaaa ggacggaacc ggcaatggag cagttttaca gctggattca
    42421 aacgataatt ttctatatga tttttatgaa tttcatgaca aatctcctgc cgggcaaggc
    42481 gtacgccaga tacgtccgcc tgtttatggg aatggttctg atccttttgg tcattcgtcc
    42541 tctgacagga agcctgaggt tagacgagca gctggccaga cgctttgagg agatttcctt
    42601 tcaaaaagaa gcgggagagc tgcaggggca gctggaggaa atagagagac agagattcga
    42661 gacaatcgcg gacgagtatg agaaaacggt ttccgcccag gccgaggaga gactggaaaa
    42721 gagcggatac ggcggggcgc aggtgaaagt gtctgtggac agagagcagg gcagcgattc
    42781 atttggaatg atagaggaaa tggaggtatc ggtggaagat gtggaggcat gggaatattc
    42841 tgccggggaa atgccagaat cagatgaaat caataatcaa ttaaaacagt tagaaaaaac
    42901 gcagcaattg aagcaaacaa aacaatcaga gaaagaacag gaaatacgcc aggtatccat
    42961 tgaaaaaaat cagatccagg ttcatttggg gaataaggaa gaatcagagg agaaagggga
    43021 agaggggcag gagagactgg aaaacagctg cggggcagat accggagatc cggacgcaga
    43081 ggcggcgatt agaaaggagc tggcagattt ttatggactg gaagagcgtc atattaaaat
    43141 tcaaatcagg gactgagaaa aagaaacggg atcagtggat cgttcttttt gccgcaggac
    43201 ttcttctgct tctgttcagc gcatccggat ccgggaagcc tgcccacagg aaagaggatc
    43261 tgcctgtgtc tggggaggtt ttggaaaaga tggacagaac tggggctaat gataatgaca
    43321 gaggcagaga aacgggggga ggtaatgatg gcagtggcag agaacaggag gagaaggacg
    43381 cagaggcgtc tgctctgtct gcctatgaaa aacagctgga ggaacgtgtg aaggagcttc
    43441 tcaggatgac agagggggtg ggggaggccg atgtgatgat tgtcctgaaa tcatccggcg
    43501 aaaagattat ccatgaggat cagaaacggc gccgggcttc ctctgaggag acagacagcg
    43561 ccggaggaac cagaaaaacg gtggatgagg aggcggaaaa aagcgctgtg tttgtggaaa
    43621 acggttcaga aaaagagccg attgtggaaa aagagctccg ccccgctgtg gagggcgtcg
    43681 tcataagcgc ccagggagga ggaaacgctt ccgtgaaaac ggaaatttct gaggcaatgc
    43741 aagcattatt taatataccg gcacataaaa taaaagtatt aaaaagggtg gattaaagga
    43801 gcggtgaata tgaaagtgaa gcgaattttc agacgaaacc agattattat tacgacgctg
    43861 gccattatga tagcagctgc cggatatttg aattattctg gaaaagagga gctttccggt
    43921 gccgtgtatg aggcgggagt tatggaaatt tcggacgagg atatcttagc tgaaaatcag
    43981 gcggtgggaa acttaaatcc tgaggcagag ggagccggag aggaggtatc cggcccggcg
    44041 gaggccgaga cgaaacagcc tggagcgcag caggcggagg cgcagcaggg gaaggaagga
    44101 gaaagcagcg tgagcgcagg cagcgcagag gcagaggagt acaaggagat tgccagcctg
    44161 gatcaggaac cgggagagga ggctggatcg gaacaggcag attcctctat cgataacccg
    44221 ggggaggcag tgttaactgg gggaaccagc gttacagact acatagctaa tgtgcagctg
    44281 agccgggagc aggtgagggc gaaaaataag gaaaccctga tggagattat taataacgag
    44341 aacgccgatc cgcaggccaa ggagacggcg gtccaggaca tgattgacat gacggcagta
    44401 gcggagaagg agaatgcggc ggagacgctt ctcatggcca agggcttcgc cgatccggtg
    44461 gtcagcatta cagacggcaa ggtggacgtg gtgatcaacg cctcctccct gacggatccg
    44521 gagcgtgccc agatagagga tattgtcaaa agaaaggctg aggtgacggc ggaaaacatt
    44581 gtcattacgc tgatgaagct tcaggagtaa ttgcggttag atcttgcaaa cgcccgccta
    44641 tctgctataa tgaaactatc acagaaaaga caggaggtag cggggatgcc gaaggaagct
    44701 gcggagaaaa acatacatgt attagagaga gacggtaagc tgggtgaggt gaagatcgca
    44761 gacgaggtgg tggctatgat tgccggcctg gctgccacag aggtggaagg cgtggactcc
    44821 atggccggaa atatcaccaa cgagctggta ggaaagctgg gaatgaagaa tctcagcaag
    44881 ggcgttaaag tagaagtgag cgaggagcac gtttccgtag acttatcgct gaatatgaag
    44941 tatggctaca gccttccggc tgtcagcgag aaggttcagg agagggtgcg gactgccatt
    45001 gagacgatga cagggctgac ggttctggag gtcaacatca aaatcgccgg agtcaatatg
    45061 agggaggaaa gctaggaagc agtctgccgc tctgataaaa ggctctgcta aaagttcgtt
    45121 aagaagtgaa caattaagct gtatttcttg acgaactatg aaaaatgtgg tagtatcttt
    45181 agcgttaaaa gggagtagtt attaacatgc agtcaacata cgccgggcgg agagcctgtg
    45241 gttgcatgtc ttttgtttat aagacagaag aacaagactt ttagcatatg gtttcatatg
    45301 ctaaaagtct ttttttgttt cgtgggaaag cgcctgacag gaaggaagtt tccggacatg
    45361 aagtaagacc gcgtggatag tgaaccccct gaaatgagaa aaagggaaga aaaaaaagaa
    45421 attaggaggg aaagaaatgg actttttact ggaaggcatt ctggccatca cgccgcagca
    45481 gctggtcatg tatgtagtag gagttctgct catctggctc gcaattaaga agggctatga
    45541 gccatctctg ctcctgccga tgggctttgg agcaatctta gtaaacctgc cgttatccgg
    45601 cgttatcaac caggtgatgg aaggcgtagg agagacgcca ggaattattc agtggttatt
    45661 tgagacgaca atcgaggctt ccgaggccct tccgattctg ttattcatcg gtatcggagc
    45721 aatgatcgac ttcggcccgc tgctgtccca gccagttatg ttcctgttcg gagcagccgc
    45781 tcagttcggt atcttcttcg ctatcatggt agcagtttta ttaggctttg atttaaagga
    45841 cgcagcgtcc atcggtatca tcggagcagc cgacggcccg acctctatcc tggtatctca
    45901 ggtgcttcac tccgactatg tgggagcgat tgcggtagcc gcttactcct atatggctct
    45961 cgttccgatt attcagccgt ttgcaatcaa gcttgttact acaaagaaag agcgctgtat
    46021 tcatatgaca tacagcccga aggcagtttc caagacaaca aagattgcct tcccgattat
    46081 cgttacgatt atcgtaggac ttatttcccc ggcatccgtt gccctggtag gcttcctgat
    46141 gttcggtaac ctgatccgcg agtgcggtgt gcttcagtcc atgtccgata cagctcagaa
    46201 cgagcttgca aacctgatta cactgctgct tggaatcact atttccttca gtatgagagc
    46261 cgacgcgttc gtacgcttcg acactatcct catcatgtgc atcggtctgg tagcgttcgt
    46321 attcgatacc atcggcggcg taatgttcgc caagatcatc aacctgttcc gcaaggagaa
    46381 gattaacccg atgatcggcg gcgctggaat ctccgcattc ccaatgtctg cccgcgtaat
    46441 ccagaagatg gctcaggagg aagagaaagg taacatcatc ctgatgcacg cagtaggcgc
    46501 taacgtatcc ggccagattg cctctgtaat cgcaggcggt cttgttatca agctggtgac
    46561 acagttcctg taggagggaa aagattatga tggaaaactt tttaatcgct cttcagatta
    46621 tggcgcaggg aatgggcgga atcttcgtag taatcattct gattaccctg gttgttatgc
    46681 tgatgggaaa gatgaataaa taagatgtgt taggaaaaaa ggaactgttt tcgtgctcca
    46741 ctggaagtcg ctgaaaacag ttcctttttt cataggcggg ttcgcaggaa atggcaggaa
    46801 acagttcctt tttttcatca aaagtaaatt tattttactg taatcctatt agaaagatta
    46861 caaacgctgc aattgttata agagtccagg cggtatatct tcctgcaatt tcccagtcag
    46921 acggccctgc ctaagttcca caccaacgat accttccagc gttttttctt cctctggaat
    46981 agcagtatta tcttctttta ctgtatatgg gccgtagatt ttattgccat agtgaaatac
    47041 aactgtctta tcctgcgaca ctgaaaaata tgctttctgc cctcggagtc tgccggagta
    47101 cacggtactg ccattttcct gacttgggac aaaaattgca tctttatatt caaatccaac
    47161 ttttgaaatt gtcatggaat aaattactgc aaataccagc gccatagcaa tcataacgac
    47221 tagaacactt ttttggtacc agtttaaacg tttgattttt tccatcattc tgcctccttt
    47281 ctaaacctga atataatatg ggacaatcca ggccagcccc ttcattattt gatagaaaga
    47341 ctaactatta aaagtcaagc ctaaaataaa agttttttga atgaattgta gaaatgcatt
    47401 tcagatatat ttgaaccttg aaaaccgcat gacaaaaaga gcatctttgc aggtgctcta
    47461 aaaagagata gttacagaaa aattaagtgg ctggcagata tgcttttctg gatttctcca
    47521 ttgcaaaaat caatcgcaca agcttcttag cggcatggga tatggcaaca ttataatgct
    47581 tgccttccga gcgtttcttt gcaagatatt caccaaagga tttatcccag tgacagacgt
    47641 attttgtggc gttgtaaagg gcataccgga ggtatctgga acctcgtttc tccatatggg
    47701 aataacagtt atctaactgc cctgattgat aagtagaggg agacattcct gcgtatgcga
    47761 ggatcttatc tgcagaatca aaacggcaga aatctccaat ctcagcaata atcatggcac
    47821 ccatccggta actgatgcca ggaatggtaa gaatcggtga ctggatttct tcatccatga
    47881 tctgtttgat ggcggcttcg atttcatcaa tttcagaagt caattcttga atgagtttaa
    47941 tggtgtgttt cagttccaag gattttgtag gcatattcga accgattgag tttctggcag
    48001 cttcacgaaa catgacagca gtgtcttttc cgtatctgtt ctttgaactt tgggagagca
    48061 gattgataag ccgagtaaga tgtgcagatg caacagcgtg agcagatgga aattcagata
    48121 acaaagcgta aacagatgcc atatgaaggg ttggaacaag cttttctaat tctgggaaaa
    48181 ggatacagat aagccgtgag acagatgttt tgagttttgc acgttccttt actttatcaa
    48241 aacgataacg a
//
LOCUS       DBMDUW010000014        47477 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_691_length_47477_cov_4.299033, whole genome shotgun sequence.
ACCESSION   DBMDUW010000014 DBMDUW010000000
VERSION     DBMDUW010000014.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 47477)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 47477)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47477
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_691_length_47477_cov_4.299033"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(48..722)
                     /locus_tag="ACZPCR_04490"
     CDS             complement(48..722)
                     /locus_tag="ACZPCR_04490"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002568044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0000270 - peptidoglycan metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HIR1230163.1"
                     /translation="MIKNRGWKLLGMMCVCSAVLFANPAKAEAAEAEEGAVVKVEVEQ
                     VSLYSEMNAESAVVEQASQGDTYEVVEDNGDGWVKVFSESGEEGYLMADGKSAVVEAE
                     AGDVRQDVVDYALTFLGNPYVYGGSDPNTGTDCSGFTSYVLEHAGGVDMNRSSRSQAT
                     QGTQVSAEQMQPGDLVFYANGSRINHVGLYIGDGQIVHASTERTGIKISPWTYRNPVK
                     IVSVLG"
     gene            complement(924..2069)
                     /locus_tag="ACZPCR_04495"
     CDS             complement(924..2069)
                     /locus_tag="ACZPCR_04495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008753462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="double-cubane-cluster-containing anaerobic
                     reductase"
                     /protein_id="HIR1230164.1"
                     /translation="MMNLPENFVTYDEARKAGFMKMKELKEKGARTAGIFCSFVPVEI
                     LMAGGVVNASLCASSEQPIPAAETKLPRNLCPLIKASYGFALTDTCPYFYFADLIVGE
                     TTCDGKKKMFELLNELKETYVMQLPAQRNERGLDLWKKEIIALKEKLEDFYGIQITEE
                     DIKKAIRLKNRERKAMLRFMELGKLYPSPISGYEISTVSDSLGFNFDMEDRIRRVEER
                     TEEVLKDWEENYKGKTSKRPRLLITGCPNGGVRDKIIKTVEEMGADVVAFDSCSGTRE
                     KVEEVDENMPVFDALAKKYLNINCSVMSPNDSRQGYIKEMIHEYQADGVVEIILQSCH
                     TYNIEAHFIKRTVEAEGIPYLMIETDYSKSDQGQIATRLEALLETIS"
     gene            complement(2245..4137)
                     /locus_tag="ACZPCR_04500"
     CDS             complement(2245..4137)
                     /locus_tag="ACZPCR_04500"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1230165.1"
                     /translation="MSNEQRKPRVTKDTLTTGKRLLGYVLRDYKLRFIGVFFCILMSS
                     IASISVSLSLKFLLDDYIIPLIGKQNPNYTELYRAMAVLGCIFLCGVIATFIYSRLMV
                     YIGQGVLKKVRDEMFEHMQKLPIRYFDQNTNGSIMSLYTNDTDTLRQMISQAIPQVLQ
                     SLLTVTVTFISMLVLSPLLTVLAVIMIGVMLFVTKTIGGNSGKYFLSQQLDIAGVTGF
                     VEEHMTGQRVIKVFNHERIAEEEFDKLNEKLFVSASRANTFANMMGPVIGNIGNLQFV
                     LTAVLGGFLSVMGIGGITLGVMASYLQFTKSFTQPFMSIAQQFNSIIMALAGAERIFR
                     LMDEEPELDEGYVTLVNAKKDENGNLTECRERTGLWAWKHPHQSDGTVTYTELKGDVR
                     FFDMTFGYTEEKMVLHDLTLYAKPGQKLAFVGSTGAGKTTITNLINRFYDVQDGKIRY
                     DGININKIKKADLRRSLGIVLQDTHLFTGTIMDNIRYGKLDATDEEIYAAAQLAHADQ
                     FIKMLPKGYDTMLTNDGEELSQGQRQLLAIARAAVADPPVLILDEATSSIDTRTEQIV
                     QKGMDNLMKGRTVFVIAHRLSTIRNSDAIMVLEHGRIVERGSHEELIKEKGIYYQLYT
                     GKLELD"
     gene            complement(4130..5863)
                     /locus_tag="ACZPCR_04505"
     CDS             complement(4130..5863)
                     /locus_tag="ACZPCR_04505"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009203493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1230166.1"
                     /translation="MNRKLFKSIREYRRESILAPVFVILEVLMEVLIPLQMAKIIDVG
                     IAQGNLPYIVRMGVILVAMAMIALFFGAMAGKFAAVAAAGYAKNLRHDIFYKIQNFSF
                     KNIDHFSTSSLVTRLTTDITNVQMAYMMSIRLLARAPFMIILSLIMILTINWEISLIL
                     LVLVPVLGGLLMFIAKKAHPHFIRVFDEYDVLNNSVQENVNASRVVKAYVREEHEIEK
                     FHGVSKLVYDLFTRAEKIVAWNAPTMQFFMYSIILLMVSIGGKSIIGQTMETGELTSV
                     IVYAIQILISLTMVTFVFVMIMIAEASTDRISEVLDEVPEMQDPAGAVTEVPNGDIDF
                     EHVSFSYGGKGGNLSLKDINLHIKSGQTVGIIGGTGSAKTSLVNLIPRLYDVTEGSVK
                     VGGIDVRSYGLEALRDQVSMVLQKNVLFTGSIYDNIRWGDENASDEEVQRVCRLAQAD
                     GFVQEFPAGYNTMIVEGGNNVSGGQKQRLCIARALLKKPKILILDDSTSAVDTKTDAL
                     IRKAFREEIPDTTKIIIAQRVSSVEDADMIIVMENGKVNGVGTSEALLKTNAIYREVY
                     ESQVKGGEDYE"
     gene            complement(5892..6389)
                     /locus_tag="ACZPCR_04510"
     CDS             complement(5892..6389)
                     /locus_tag="ACZPCR_04510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HIR1230167.1"
                     /translation="MCTEAEKSGELCCKSAGRMVNILSNQLKRRFLVPDDGNELTMLQ
                     RHMLHFIIVGSMHQDIFQKDVEAEFQIRKSTATGILQLLEKKGFICRESVERDGRLKR
                     VAPTEKALAMRERVMQSLRCAETQMLQGIAREDLDICMQVLAQMSRNLSCKEQDCKEQ
                     ECRLT"
     gene            6679..6891
                     /locus_tag="ACZPCR_04515"
     CDS             6679..6891
                     /locus_tag="ACZPCR_04515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016291306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230168.1"
                     /translation="MKEFTYVALRQKPELKEAAAWFHDKWEVPQEAYLECMEAYLNHE
                     TEYGWEFLCMVQGDNDPDMTRMYIHR"
     gene            6997..7731
                     /locus_tag="ACZPCR_04520"
     CDS             6997..7731
                     /locus_tag="ACZPCR_04520"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230169.1"
                     /translation="MKKATVIPTVSVLIALVCAALFCLNWNPEPLLKGKEQPVTLSDI
                     EQNLTTDFNGFPAGEDIPRLTSAEDFSEIIYLSDYVTAEPVGIVETGISSLKPWEDQY
                     YTQRVKGRATGRQIRQPEITSSGLDLLGSYQPYYLLELPDHTYIVAQIPPQTAKAIEK
                     GESITLPVGEKVSMTNAARNELSAICEEYGTDMDGVFYAVNDKWQEEHQFILFLLRFG
                     AAALIWFVLAAGLMLAGWKLFKCDEG"
     gene            7758..8042
                     /locus_tag="ACZPCR_04525"
     CDS             7758..8042
                     /locus_tag="ACZPCR_04525"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230170.1"
                     /translation="MNELQKRFFEYLAAVQETCVEVCMIQHKCDDEKTKRMLYDVTFE
                     AITAIMEMIDGYSAFSGNKHDIVNTVTGEHLKENPFIELHDQAAGFFKYE"
     gene            complement(8161..8721)
                     /locus_tag="ACZPCR_04530"
     CDS             complement(8161..8721)
                     /locus_tag="ACZPCR_04530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018595488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015109 - chromate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015703 - chromate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HIR1230171.1"
                     /translation="MIYLQLFFSFLKVGMFSVGGGYAAIPLIQSQAVEACGWLTMDEF
                     TNLVTIAEMTPGPIAINAATFVGIRIAGISGAAAATLGCIFPSFLIVSFLAFLYYKYK
                     GGSFVSSVMSSLRPAVVALIAAAGLSMLNTAVFNGRAASIGNLDVISAALFLLAFLLL
                     RTRKWNPILVMCLCGAANLAIGTALQ"
     gene            complement(8718..9347)
                     /locus_tag="ACZPCR_04535"
     CDS             complement(8718..9347)
                     /locus_tag="ACZPCR_04535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018595487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015109 - chromate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015703 - chromate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HIR1230172.1"
                     /translation="MEEKPLETGQGWENGRREPRWRRLWLLFSGMFYISAFTFGGGFV
                     IVTFMKRKFVDTLHWLDEQEMLDFTALAQSSPGAIAVNAAILVGLKICGAAGMAAAVL
                     GTILPPMIILSVVSFFYSAFSSNLFVALALKGMQAGVAAVILDVAWDLGEGMVKKKSL
                     YLNLILAGAFAADLFLGVNVIYIILAAAGAGILRAVLQKKDKEGREGSL"
     gene            9604..11445
                     /locus_tag="ACZPCR_04540"
     CDS             9604..11445
                     /locus_tag="ACZPCR_04540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016441590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding protein"
                     /protein_id="HIR1230173.1"
                     /translation="MSRLSIVTTSRAQTVVEGLYKDLERRIIASPPGLCPVDLTASFL
                     KMCMAQTCGKCVPCRIGLSQLDLLLNDILEGRGTLDTLNLIEKTARVISSSADCAIGY
                     EAANMVLKGLSGFREDFLNHIESNRCLYHLDQPVPCVALCPAGVDIPGYVALVAAGRY
                     ADAVRLIRKDNPFPTACAMVCEHPCESRCRRNMIDDAVNIRGIKLAAVDNAGIVPPPP
                     CAPSTGKRIAIIGGGPSGLSAAYYLQLMGHQTTVYEKRSKLGGMLLYGIPSYRLPRER
                     LQEDVDAILATGVEVKTDTAVGSEPGQVSMDFLRKEYDAVYISIGAHTDKKVGIEGED
                     AEGVISAVEMLREVGRGRMPDFTGKRVCVIGGGNVAMDVTRSAIRLGASHTTVVYRRR
                     KDDMTALPAEVEGAVAEGAEVLELHAPERIETDENGRVAALWASPKMIGLIKDGRPSP
                     ASSGENPVRIPCDIVIVAIGQGIETRHFEDAGIPIKRGVIQAANWSAVEHAPGVFAGG
                     DCVTGPATVIRAIAAGKVAAANIDQYLGFDHIISVDVDIPEADFSDRPPCGRVNMKER
                     DANERKHDFDLAECPMSLKEADQEAHRCLRCDRFGYGNFKGGRTTEW"
     gene            11439..13193
                     /locus_tag="ACZPCR_04545"
     CDS             11439..13193
                     /locus_tag="ACZPCR_04545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005348317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent [FeFe] hydrogenase, group A6"
                     /protein_id="HIR1230174.1"
                     /translation="MVNLTINKQHVCVPEGTTILEAARQIGIKIPTLCFLKEINEIGA
                     CRVCMVEIAGISRLVTACNTPVTEGMEVITNSARVREARKTNVELILSQHHTDCPTCV
                     RSGNCSLQKIANDLNLVANEYPVRYAETKWTSTFPLVRDAGKCIKCMRCVQICDKVQS
                     LNVWDVSNTGSRTTVDVSMGREIKMSDCSLCGQCITHCPTGALQERDDVSRIFDIHGD
                     LSNPDKITVVQIAPAVRAAWGEEFGLSRDFATDKRMVAALRRMGFDYIFDTTFSADLT
                     IMEEGSELLERLSHKEDYKWPMFTSCCPGWVRFLKSQYPEMTDQLSTAKSPQQMFGAV
                     TKSYFAARLGVDPGSVTCISIMPCVAKKQEADLPTMYDNGINGGIKDVDYVLTTREIC
                     RLIKSEQIDVASLPEEEFDSPLGEGSGAGVIFGATGGVMEAALRTSYSIVTDKNPKPD
                     AFSNVRGMDGWKEAEFKLGGTVLKTAVASGLGNTRKLINALQKGDVSYDFVEIMACPG
                     GCAGGGGQPIHDGKELAEQRSSKLYAMDQKNAVRFSHENEEVRELYHNYFGKPGSHLA
                     HKLLHTDHNGWDMPLGGK"
     gene            complement(13291..13797)
                     /locus_tag="ACZPCR_04550"
     CDS             complement(13291..13797)
                     /locus_tag="ACZPCR_04550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015528408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HIR1230175.1"
                     /translation="MPFKRVKPEELSVNPFTVIGKDWFLITAGTEKECNTMTASWGGL
                     GVIWGKPSATAYIRQSRYTKEFVDREELFTLSVFDESFRPALNLCGKVSGRDQDKIRE
                     AGLTPMEVDGTTAFEEAKMIFVCRKQYHQYMGPEGFDVKENDEKWYADKNYHTMYIGS
                     IEAVLVRE"
     gene            complement(13812..14297)
                     /locus_tag="ACZPCR_04555"
     CDS             complement(13812..14297)
                     /locus_tag="ACZPCR_04555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HIR1230176.1"
                     /translation="MKKTEFLKELEAALKGEVSPELTAENLRYYDNYISQETSKGRSE
                     AEVIEEIGSPRLIARTIIDTSGGSGSYESGESSSSGSYGGAGSASGSYGSGQGGYSRF
                     HYVNLNKWYWKALIIAVLCLVLFTVLSIVGGIFAILFRFATPILIVLLVVSLLRNMRG
                     R"
     gene            14462..15304
                     /locus_tag="ACZPCR_04560"
     CDS             14462..15304
                     /locus_tag="ACZPCR_04560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HIR1230177.1"
                     /translation="MKHESSLPCEQLYVFGTGNAAVTHCYNTCFAIRTETQPGQTEFF
                     MVDAGGGNGILGILDQMQVPLTQIHHIFVTHEHTDHILGIVWMVRMIGTQMKKGAYEG
                     TLSIYCHDGLVETIKTLCRLTLQKKFCDLIGTQILLIPVTDGETRDILGYPVTFFDIH
                     STKARQFGFTTVLKNGKKFTCTGDEPFQELCLPYVEGSSWLLHEAFCLYSQREQFHPY
                     EKHHSTVREACQLAEQLSIPNLVLWHTEDKNLSQRKWLYTEEGTEFYSGRLIVPDDRE
                     IIPL"
     gene            complement(15291..15764)
                     /locus_tag="ACZPCR_04565"
     CDS             complement(15291..15764)
                     /locus_tag="ACZPCR_04565"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0047617 - fatty acyl-CoA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HIR1230178.1"
                     /translation="MEHVKENRQNTEEPDFRTALGIKIVDRGAGWARGEMKAEKLHLN
                     PLGIIHGGCLFSLADTVSGTAIMGYGCRVTTVNGSIQFLRPGKPEGTITAVARTVKHG
                     KTFSVCDCQVFDDTDALIAATTMTFYHLEQGAEEKNQDSRAAVCAREDEGTSTAE"
     gene            16033..17142
                     /locus_tag="ACZPCR_04570"
     CDS             16033..17142
                     /locus_tag="ACZPCR_04570"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007708433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HIR1230179.1"
                     /translation="MLSLLSQQSIGAAGSDSRKDDFIKWVDFNIPEEAMTKAFRLDVA
                     TCQQQLHLNWIELLAFLGARYGGDFSSYLEADMDELASRLQSGISMEQLTADMKYYPY
                     YLEAYTAVLGGLVGYYEIQIPASEAPSFALADSTIQEDDPSCGPSSVSQGGDPGAAGE
                     NHPQSGQNPEKVWVTKYGMKGFLPIAKGFPYTDYDDFGVSRSYGYKRKHLGHDMMGQT
                     GTPVMAVESGYVETMGWNQYGGWRIGIRSFDKKRYYYYAHLRKDYPYQSCLSEGSIVT
                     AGDVIGYMGRTGYSSTENTNNIAKTHLHFGLQLIFDESQKEGNGEIWVNCYELMKFLS
                     INRSEAAKKEGTKEWERIYGMKDPAVAEAEHSRNP"
     gene            complement(17292..18455)
                     /locus_tag="ACZPCR_04575"
     CDS             complement(17292..18455)
                     /locus_tag="ACZPCR_04575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002568085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HIR1230180.1"
                     /translation="MRKIHCLNPISEHGTGLFTEGYEMTENAGEADGILVRSASMHGM
                     EFSENLRAVARAGAGVNNIPLDECASCGIVVFNTPGANANGVKELVLAGMLLAARDVA
                     GGMNWCRENAGNENISKDMEKAKKAFAGNEIKGKKLGVIGLGAIGAEVANAAAGLGME
                     VLGYDPFISVNAAWMLSRDVRHITDVDTIYSQCDYITVHVPLLDSTRGMINRESMAKM
                     KDGVVILNFARDLLVNDADMKAALAEGKVKRYVTDFPNPAVMEMEHVIATPHLGASTE
                     ESEDNCAVMAVKELMDYLENGNIRHSVNYPDCDMGVCTSVNRVALLHMNVPNMIGQIS
                     AILAATDMNIANMVNKSREKYAYTMIDLETKVDQETLEKLKGIKGMMRVRVIQ"
     gene            complement(18481..19563)
                     /gene="serC"
                     /locus_tag="ACZPCR_04580"
     CDS             complement(18481..19563)
                     /gene="serC"
                     /locus_tag="ACZPCR_04580"
                     /EC_number="2.6.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0004648 -
                     O-phospho-L-serine:2-oxoglutarate aminotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006564 - L-serine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoserine/phosphohydroxythreonine
                     transaminase"
                     /protein_id="HIR1230181.1"
                     /translation="MSRVYNFSAGPAVMPEEVLREASEEMMDYRGCGMSVMEMSHRSR
                     DFQDILKEAEQDLRDLMEIPDNYKVLFIQGGGHMQFAMVPMNLMKNKVGDYIITGQWA
                     KKAFKEAQMYGTAHAIASSEDKTFSYIPDCSDLPVDEDADYVYICLNNTIYGTRFPEL
                     PNTKGKTLVADVSSCFLSEPLDVSKFGIIWGGVQKNVGPAGMAIAIVREDLITEDVLP
                     GTPTMLRYKTYADNDSLYNTPPTYCIYICGKVFKWLKKQGGLAAMKEKNERKAKLLYD
                     FLDESQLFKGTVEKQDRSLMNVPFVTGSEEMDAKFIKEAKEAGFVNLKGHRTVGGMRA
                     SIYNAMPEEGVAKLVEFMREFERKNS"
     gene            complement(19622..21310)
                     /gene="ilvB"
                     /locus_tag="ACZPCR_04585"
     CDS             complement(19622..21310)
                     /gene="ilvB"
                     /locus_tag="ACZPCR_04585"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HIR1230182.1"
                     /translation="MKRLNGAEIVIECLKEQGVDTVFGYPGGSILNIYDALYKHQDEI
                     THILTSHEQGASHAADGYARATGKVGVCLATSGPGATNLVTGIATAYMDSIPVVAITC
                     NVGVNLLGKDSFQEIDILGVTMPITKYNFIVKDVTKLADVIRRAFKIAGSGRPGPVLV
                     DITKDVTAAECDYEYKQPDPVKPLSDTITEEDMERALSLIHASQKPFIFVGGGAVSAN
                     ASEELKAFAHKIQAPVADSLMGKGAFDGTDELYTGMIGMHGTKTSNFGVAECDLLIVA
                     GARFSDRVVGDSSRFAKNAKILQLDVDPAEINKNIHTTASVIGDLKVILRRLNARLDP
                     MNHEEWIAHIDRMRDMYPLRYNKEQLTGPYIMEKIYELTDGEAIITTDVGQHQMWAAQ
                     YYKYKKPRTFLSSGGLGTMGYGLGACIGAKMGCKDKTVVNIGGDGCFRMNMNEIATAA
                     RYNIPIIQVVFNNHVLGMVRQWQNLFYGKRYSQTVLDDQVDFVKVAEGLGAKAYRVTE
                     KDEFERVFKEAVELNIPVVIDCQIGCDDKVFPMVPAGKPIEDAFDEIDLMIEGK"
     gene            complement(21374..23053)
                     /gene="ilvD"
                     /locus_tag="ACZPCR_04590"
     CDS             complement(21374..23053)
                     /gene="ilvD"
                     /locus_tag="ACZPCR_04590"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012201350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HIR1230183.1"
                     /translation="MKSDAVRKGPQAAPHRSLLNALGMTPEEMRKPMVGIVSSYNEIV
                     PGHMNLDKIVEAVKLGVAMAGGTPVVFPAIAVCDGIAMGHVGMKYSLVTRDLIADSTE
                     CMALAHQFDALVMVPNCDKNVPGLLMAAARVNVPTVFVSGGPMLAGHVGGRKRSLSSM
                     FEAVGAYAAGNITEEELTEYENKVCPTCGSCSGMYTANSMNCLTEALGMGLRGNGTIP
                     AVYSERIKLAKHAGMKVMEMYEKNIRPRDIMTEKAFLNALTVDMALGCSTNSMLHLPA
                     IAHEAGVDLNMDLVNEISAKTPNLCHLAPAGPTYIEELNEAGGVYAVMNELSKKNLLN
                     LDCMTVTGKTVGENIEGCVNRNPELIRPIENPYSATGGIAVLRGNLAPDTAVVKRSAV
                     APEMLKHQGPARVFDCEEDAIAAIKGGKIVPGDVVIIRYEGPKGGPGMREMLNPTSAI
                     AGMGLGESVALITDGRFSGASRGASIGHVSPEAAVGGNIALVEEGDMISIDIDNHSLN
                     VLVSDEELAERRAKWQPREPKVTTGYLARYASMVTSGNRGAVLEIPGKKQD"
     gene            complement(23138..24223)
                     /gene="leuB"
                     /locus_tag="ACZPCR_04595"
     CDS             complement(23138..24223)
                     /gene="leuB"
                     /locus_tag="ACZPCR_04595"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008395553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HIR1230184.1"
                     /translation="MDYRIAVIPGDGIGPEIVREACKVLDRVGAVHGHKFQYTEVLMG
                     GISIDTYGVPLTEEALETAKNSDSVLLGAVGGNVGNSRWYDVAPNLRPEAGLLAIRKG
                     LGLFANIRPAYLYKELSEACPLKKEIIGDGFDMVIMRELTGGLYFGERYTKEVDGVAT
                     AVDTLTYNENEIRRIAVKAFDIAMKRKKHVTSVDKANVLDSSRLWRKVVEEVARDYPE
                     VTLTHMLVDNCAMQLVMNPGQFDVILTENMFGDILSDEASMITGSIGMLSSASMNESR
                     FGLYEPSHGSAPDIAGKGIANPIATILSAAMMLRYSFDLDQEAAAVETAVQQVLTEDF
                     RTADIMAEGCVQVGTEEMGRLICERIK"
     gene            complement(24518..25282)
                     /locus_tag="ACZPCR_04600"
     CDS             complement(24518..25282)
                     /locus_tag="ACZPCR_04600"
                     /EC_number="4.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF015297.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016830 - carbon-carbon lyase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase family protein"
                     /protein_id="HIR1230185.1"
                     /translation="MEQLKQKVTNRELTLGTMLSELAEPNIVRILKTAGFEFVIIDCE
                     HGYFDLSQTAALIGMGSCCGLPVFVRVPSTGREYITKVMDMGAAGLLVPMVNSAEDAR
                     QAVEYAKYTPLGKRGISTQRAHTNYAPPPLEEYLKMANQRTMIMVQLETREALGHIRE
                     IAETEGVDALMIGPNDLAADLGMPGQVESKEILKAAELAAEEAARAGKSSGIITSKKT
                     LIHSCRELGMNLFSCDSEVGMLIKAAKQSVQQFWQK"
     gene            complement(25292..26656)
                     /locus_tag="ACZPCR_04605"
     CDS             complement(25292..26656)
                     /locus_tag="ACZPCR_04605"
                     /EC_number="2.7.1.14"
                     /inference="COORDINATES: protein motif:HMM:NF012589.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0050277 - sedoheptulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sedoheptulokinase"
                     /protein_id="HIR1230186.1"
                     /translation="MYYIGIDIGSTYVKSVLIDMEAGKARQEQRFPAPAKRELKNRRC
                     FEISAEELLAMVRTQAECFADLYEDIKGVILSTQMHGFVYCTEGREDRYISWQDMRCL
                     DRKNEQETYMDSLAADISRQDMENHGVYIKPSLGLCNLYTLLEEEDLPRDGELFTLGS
                     YIIAGLTGENRCHIMNAAPLGLADVKNCCWDKPLLERLGFHQIRLPKLAESDTEICGF
                     WSYKGTEIPVYPDFGDQQCAILGSMTRQRDAVINIATASQVSVTTKEFRPGPYEIRPY
                     FGNQYINTISNMPSGRNLDVLIDFLGEFYQRLSGQKAEKTDLWKAALQGYDGQADGLL
                     ADMSFYALPDKRQGGEIRGITNVNLNTEHLFAAAFENMADTYWEHIKKLAEEEEIQRL
                     VCAGGVSWKRPELLKKIGERSGKLCTLSAVPDEALNGLYRIALLCEGSCQTPEEHPEL
                     ILQG"
     gene            complement(26673..27029)
                     /locus_tag="ACZPCR_04610"
     CDS             complement(26673..27029)
                     /locus_tag="ACZPCR_04610"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HIR1230187.1"
                     /translation="MENKKVEFKLLHVGINCVDGEEAKKTAEQFSQAMGFDISENPSS
                     LFAGTSVEIMKKPYLGRLGHLAYGVEDIEAALNYLEERGLKRDMSTAVYREDNSLSVV
                     YLEGEIGGFAIHLKQL"
     gene            complement(27070..28104)
                     /locus_tag="ACZPCR_04615"
     CDS             complement(27070..28104)
                     /locus_tag="ACZPCR_04615"
                     /inference="COORDINATES: protein motif:HMM:NF015445.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HIR1230188.1"
                     /translation="MKKAVISILMAGILAVNLAGCSGGTDNSKNAENSSGENYTITLT
                     HAVAEDTSQQAGCLAFKEYVEENSEGKITVNIYPNSQMGGDREQIEGVQEGSITMMTC
                     GSAAQANFVNSAIVFDGPFAFQTEEQMEKVFADQEFIDALSAEYDKAGFYMMGLSSLG
                     FRVTTANKEIRVPEDVKGLTIRTMENKYHMSLWKNLGANPTPLAFNELYTALQQGTVE
                     AQENPLELVYAQKFYEQQKYVIETRHLPQNLVWIMNKNYYDSLPDDLKAVVDEGAKKA
                     VEGSVSYYKENNAELEKKVTEAGVEIIDLTPEELAPFAEATASVWDEVKADCGETVYT
                     AFMNALEASK"
     gene            complement(28152..29132)
                     /locus_tag="ACZPCR_04620"
     CDS             complement(28152..29132)
                     /locus_tag="ACZPCR_04620"
                     /inference="COORDINATES: protein motif:HMM:NF012607.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003682 - chromatin binding [Evidence
                     IEA];
                     GO_function: GO:0003714 - transcription corepressor
                     activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA];
                     GO_function: GO:0140297 - DNA-binding transcription factor
                     binding [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C-terminal binding protein"
                     /protein_id="HIR1230189.1"
                     /translation="MKKFVMLDAHTLPEADYHQEREILAEAGYECVIAQCKTMDEVVD
                     FCSDADVIGDVYFKIDDVLLSKLPKLQAVIRYGIGYDVVDIEAAGRRGVAVCNLPTYC
                     VEDVASHALGLILDLRRKLTLYDRRLHEGQWDPGYGYEMHRFSSTVLGLMGFGRTARI
                     LAGFAKGLGMKVLASDPYLPAEVFREHGVEPVSYEEIYSQADIISLHVPATEETKHLI
                     CRETIGKMKDGVMIVNTSRGSIINLQDLMDALDSGKVAAVGLDVMEGEPISDKNARLF
                     QFEQAVVTPHVAYSSAEASDEQHTQAAQTAVRLLRGERPENIVNKKQLGL"
     gene            complement(29163..30452)
                     /locus_tag="ACZPCR_04625"
     CDS             complement(29163..30452)
                     /locus_tag="ACZPCR_04625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015568354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HIR1230190.1"
                     /translation="MNIGIVLAAFFVTIFLGIPIGVSVGLTSLTASWANPSLPATADF
                     IFRNMVTALDTYALLAVPLFILSGVIMAQGGISKKLFDFFAYFVGNRTAGLPIAVIVT
                     CLFYGAISGSGPATVAAVGAMSIPLLVRLGYEREFVTAMVAVSGGLGVIIPPSIPFIM
                     YGLSSGESVGKLFIAGILPGILIGLFLMIYAYGYCRIKGEDKEKLKANYESIRKQGFF
                     RTFRDSFWALLTPVIILGGIYGGIVTPTEAADISVIYALVVSIFIYKTFKISDIPGAL
                     KEAAKTAAPVLLVVSTATVFGRVLTMMQAPQMIASVMTASFTSKIEVLLVINVFLLFV
                     GMIMDTTPAILILTPIFLPIVTQLGISPIHFGVIMVVNLAVGFVTPPIGVNLFVASSL
                     TKIPVIQIAKKAVPFILVFLAALLLITFVEPISLLLV"
     gene            complement(30449..30931)
                     /locus_tag="ACZPCR_04630"
     CDS             complement(30449..30931)
                     /locus_tag="ACZPCR_04630"
                     /inference="COORDINATES: protein motif:HMM:NF016200.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015740 - C4-dicarboxylate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HIR1230191.1"
                     /translation="MKVLRWLDRHFEETIMLILLAMIVVVMGIQVVMRYGLKSSLVWA
                     EELSRYFFIWFVFMGISYGVRQNIHIKVDIIETVFPRTKRILGVLQDIAFLAFSVYMI
                     QPGFKAMGMLIASSQKSPAMGVPMYLVYISLMGGFLLTIVRMIQKYVLLLAGKGDKKE
                     "
     gene            complement(30960..31643)
                     /locus_tag="ACZPCR_04635"
     CDS             complement(30960..31643)
                     /locus_tag="ACZPCR_04635"
                     /inference="COORDINATES: protein motif:HMM:NF019349.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HIR1230192.1"
                     /translation="MAAIDSVTRTITVANVIENLRDRIILGEYPDGVMLTELALAGEY
                     GTSRGTVRTAMQMLESEGLIETLANGRKRVCGITKQFVHDLYETRALLECQAVRTILQ
                     KDYVNFGPLYEAVDVFQKLSQEQPDVMKEERFNANDRFHKTLLIMSDNKPLLRCWNTI
                     EPTIQALAKFNSNTLDPKTHSADYVKSHSRLLELLVTKDSEIETELRTHIDLAKRDSL
                     NGLRINQCI"
     gene            complement(31852..32124)
                     /gene="yajC"
                     /locus_tag="ACZPCR_04640"
     CDS             complement(31852..32124)
                     /gene="yajC"
                     /locus_tag="ACZPCR_04640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008395554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HIR1230193.1"
                     /translation="MNAMGWIVYFVFLIGLMYFIAIRPQKKEKKKMQELLASVAIGDS
                     VLTSSGMYGVVIDMTDDTVIVEFGSNKNCRIPMRKDAIVQVEKPEL"
     gene            complement(32171..33310)
                     /gene="tgt"
                     /locus_tag="ACZPCR_04645"
     CDS             complement(32171..33310)
                     /gene="tgt"
                     /locus_tag="ACZPCR_04645"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008395555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HIR1230194.1"
                     /translation="MEYKILAKDGRAKRAEMKTVHGTIQTPVFMNVGTVAAIKGAVST
                     DDLKTIGTQVELSNTYHLHVRTGDKLIKQFGGLHKFMHWDRPILTDSGGFQVFSLSGL
                     RKIKEEGVYFNSHIDGRKIFMGPEESMQIQSNLGSTIAMAFDECPPSKASREYVQNSV
                     ERTTRWLKRCKAEMERLNSLPDTVNKEQLLFGINQGAVYEDIRIAHAEEISRLDLDGY
                     AVGGLAVGESHEEMYRILDEVVPHLPEEKPTYLMGVGTPANILEAVDRGVDFFDCVYP
                     SRNGRHGHVYTNHGKLNMFNAKYELDPRPIEEGCQCPACRSYSRAYIRHLMKAKEMLG
                     MRLCVLHNLYFYNKMMEEIRDAIEHHRYAEYKAEKLARMAEGEKN"
     gene            complement(33300..35423)
                     /gene="secD"
                     /locus_tag="ACZPCR_04650"
     CDS             complement(33300..35423)
                     /gene="secD"
                     /locus_tag="ACZPCR_04650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005540241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031522 - cell envelope Sec protein
                     transport complex [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecD"
                     /protein_id="HIR1230195.1"
                     /translation="MKSSKGKAMVRLALLLVLIAIAGFFGYSYMDDIKLGLDLAGGVS
                     ITYQAKEENPSAEDMSDTIYKLQQRVESYSTEAEVYQEGDNRINIDIPGESDANEILT
                     ELGKPGSLAFMDSQGNTILTGDQVASAQGGMVDGNTGKEYVVSLTFTEEGTKAFADAT
                     TNNVGKPIYIVYDNEVVSAPVVREAITGGQCTIDGMSDFEEAENLAATIRIGSLSLEL
                     EELRSNVVGAKLGQQAITTSLKAGAVGFAIVAVFMIAVYLIPGLAAVLALSLYVGLIL
                     ILLVSFEVTLTLPGVAGIILSIGMAVDANVIIFTRIKEEIGAGKAVKTAIDNGFQKAL
                     SAIVDGNVTTLIAAAVLFWRGSGTVKGFASTLAIGIVLSMFTALFVTRFALNALYSLG
                     IENAKFYGIKKETAPKPFLKYRKFCFVLSAAAVAAGFVFMGMNRSSTGQILNYSMEFK
                     GGTSTNVTFNEEMSQERIESEVVPLVEEITKDADVQTQRVTGTNEVIIKTRTLNVEER
                     QAFEKAMQENFGVEEGKIAAESISGAVSQEMKRDAMAAVIIATIGMLLYIWLRFKNIR
                     FAGSSVLALVHDVLVVLACYAAFKWSVGSTFIACMLTIVGYSINATIVIFDRIRENMK
                     ERRRDQSLEEVVNLSITQTFTRSINTSLTTFIMVLALYIMGVSSIREFALPLMVGIVC
                     GTYSSVCLTGAMWYEMSRRKEKNGI"
     gene            complement(35410..36837)
                     /gene="scfB"
                     /locus_tag="ACZPCR_04655"
     CDS             complement(35410..36837)
                     /gene="scfB"
                     /locus_tag="ACZPCR_04655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009533448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HIR1230196.1"
                     /translation="MIHQYINNDYYIVMDVNSGSVHVVDPMLYDMIGLLSEKIDNLTE
                     PVTVPEEAKEYVFGKLEGTYPRQDMEEAFSDIQELIDMEQLFTADVYKDYVIDFKKRK
                     TVVKALCLHIAHDCNLACQYCFAEEGEYHGRRALMTYEVGKKALDFLVANSGNRINLE
                     VDFFGGEPLMNWDVVKQLVAYGRSLEEPHHKKFRFTLTTNGVLLNDEIMEFCNKEMSN
                     VVLSLDGRREVNDRMRPFRNGKGSYDLIVPKFQKFAKSRGEKDYFVRGTFTRNNLDFA
                     DDVLHFADLGFEKMSIEPVVAAPEEPYSIREEDLPKIMEEYDKLAKEYIKRHKEGKGF
                     TFFHFMLDLNQGPCVAKRLSGCGSGTEYLAVTPWGDFYPCHQFVGIDKFLLGNVEEGI
                     THPEICNEFKLCNVYAKDKCRDCFARFYCSGGCAANSYNFHGSITDAYDIGCEMQKKR
                     IECSIMIKAALADESETKEKEHEEQ"
     gene            complement(36995..37141)
                     /gene="scfA"
                     /locus_tag="ACZPCR_04660"
     CDS             complement(36995..37141)
                     /gene="scfA"
                     /locus_tag="ACZPCR_04660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HIR1230197.1"
                     /translation="MKHVKTLNTNTLKNTMRKGGCGECQTSCQSACKTSCTVGNQSCE
                     NKDR"
     gene            37295..37654
                     /locus_tag="ACZPCR_04665"
     CDS             37295..37654
                     /locus_tag="ACZPCR_04665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HIR1230198.1"
                     /translation="MKPSKLQAVVRGTLFSYVLTALLLTALAFLLYRFRLGESQVSLG
                     INLVYVVSCLAGGFLAGKAARQRRFLWGLFTGILYFLILFFASFAVSRELGAGSRELL
                     TVFLMCAGSGTIGGMVS"
     gene            complement(37777..39099)
                     /locus_tag="ACZPCR_04670"
     CDS             complement(37777..39099)
                     /locus_tag="ACZPCR_04670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016291481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HIR1230199.1"
                     /translation="MESSDAIQLLIILVLVALSAFFSSSETALTTVNKIRIRTLADAG
                     DSRAAMVLKVTGNPGKMLSAILIGNNIVNMYASSLTTLLSSKLFGNEMVGAATGVITF
                     LILIFGEITPKTSATLSSEKMSLRCAGVIFVLMVLFTPFIFVINKLSLLVLKLVGVDP
                     NKKAESITEDELRTIVEVSHEEGVIETEEKKMINNVFDFGDSVAKDVMVPRIDMAFVD
                     VNASYEEVIEIFRQEKYTRFPVYEETTDNVIGILNVKDILLAGEREQFSVRDYLRAPY
                     YTYEFKKVSELMVEMKKANVNIIIVLDEYGATAGLITLEDMLEEIVGDIRDEYDEDEE
                     NELVEIAANEYVVEGSMKLDDLNDRLELKLESEDYDSVGGLVIGLLDHLPEEGEDVVF
                     DNVRLVVDRVEKNRIDRIHLYILNPVQAVSARMKEEEERREEKKKNAE"
     gene            complement(39235..39714)
                     /gene="lspA"
                     /locus_tag="ACZPCR_04675"
     CDS             complement(39235..39714)
                     /gene="lspA"
                     /locus_tag="ACZPCR_04675"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HIR1230200.1"
                     /translation="MYLLGAAAALFGLDQCLKQLVEGQNPERFPRSMDHTGGRIKLYR
                     NHNRGFCFEVLKHRPSLVRQLPLCLTSMAGGILCFLSAQKGYRAEKAGYALVLAGGLS
                     NLYDRLRRGYVVDYFSIQAGFLKKVVFNLGDLFIMAGAAVLTVKSLFENEAGRKTQG"
     gene            39869..41608
                     /locus_tag="ACZPCR_04680"
     CDS             39869..41608
                     /locus_tag="ACZPCR_04680"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008395565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HIR1230201.1"
                     /translation="MPCSHPAASSEYADFIIRYFAFPQSLLSTIEEGCLSFINSQFAV
                     VYRPVEEALPITLNSYSYSSIPNLYTLLDASSMESSGILTSFSQPFLNTQGENTIIGI
                     IDTGIDYRNPVFLGEDRSTRILGIWDQTIELNESGVSGERAGQLPEDIFYGTAYTKED
                     IDRALASDSPLDIVPSTDENGHGTFLAGIAAGRQELSGGEAFTGAAPRAFIAAVKLKP
                     AKQYLRDYYVLPDSAEAYQENDIMMGMKYLLSLARTKRLPLTILLALGTNLGSHEGTS
                     PLAQYLDTISNFPGIITVTAAGNETGYSHHFFGTIGTDAEFEDAELRVAEGETGFTLE
                     LWSQEPELFSIGFLSPTGEQIGRIPNHTLTEQRITFVLENTVIYLNYQVAEAGTGSQL
                     IVMRFVKPTPGIWRIRVYNSLYLRGEYHLWLPSKGFISDDTFFLRPSPDTVVTEPGNA
                     SQTITAGAFNHRNGGIYIHSSRGYTRLGRVKPDLAAPGVNVDGPGIQGSAGFPMRAMT
                     GTSAAAAHVAGAAANLLSWSFREGSISYMNTSVAKTYLIRGADRNPVFAYPNREWGYG
                     TLNLYGAFLRLRE"
     gene            41737..42174
                     /locus_tag="ACZPCR_04685"
     CDS             41737..42174
                     /locus_tag="ACZPCR_04685"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230202.1"
                     /translation="MAKNRKLLFLTIALLFQIFFLYQAVFNYHVYTLDPAFRSFAEDF
                     QSDAFSDGYTGALFIAELLFQCALFLSFVYAAVSSPALSWGKLAFGAAAAFLLYQGLM
                     FLFRQFSCHCRLYMTLADTEILSLYLLLPVLQPALFQKQKMAL"
     gene            complement(42308..43723)
                     /gene="clpX"
                     /locus_tag="ACZPCR_04690"
     CDS             complement(42308..43723)
                     /gene="clpX"
                     /locus_tag="ACZPCR_04690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HIR1230203.1"
                     /translation="MDAEKEKHEAGTSDREADHKDDEYEKICYVCRRPESKAGPMITM
                     PGGMNFCHDCMQKAFDTVTQSGLDLSQLQNMPYMNMNLSDFSNLQNLNTEIPKKNKVK
                     KKSQDKEAKKEFSIKDIPAPHVIKSKLDQYVIGQEQAKKVIAVAVYNHYKRAFCQTSG
                     QEGAEDDVQIEKSNILMIGPTGSGKTYLVKTLARLLDVPLAIADATTLTEAGYIGDDI
                     ESVISKLLAAADNDVERAEKGIIFIDEIDKIAKKKNTTSRDVSGESVQQELLKLLEGS
                     QVEVPVGSNQKNALTPMTTVDTNNILFICGGAFPDLENIIKERLNQSSSMGFASELKG
                     KYDEDPKLLSYTATEDLRKFGMIPEFLGRLPIMVTLQALTKELMIRILTEPKNAILRQ
                     YEKLLAMDEVKLVFEDDALEWIAEEALKKETGARALRAIIENFMQDIMYEIPKDPNIG
                     SVVITRAYLEKSGGPMIEMRG"
     gene            complement(44069..45598)
                     /locus_tag="ACZPCR_04695"
     CDS             complement(44069..45598)
                     /locus_tag="ACZPCR_04695"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1C family serine protease"
                     /protein_id="HIR1230204.1"
                     /translation="MYNEKDWEKNHEPLNGENDVDITEGSYVDGVHTGRSEDRSAGRR
                     MYGQIRRPSEENTGCGTYQYGSSQSQEGRNESSWQKAENSGNQENGGDSHRSGKKGSR
                     LAKKAAGIAAAGLLFGCVAGGTMAGINYLTGGSQTEKTEISAQASTEAPQPETQAQAS
                     SGAVIQASTGNDVSAIVEKAMPSVVAINNKTLYTTEDWFFGTQQYEASSAGSGIIVGK
                     SDTELLVVTNSHVIANAEEMNVTFIDGSSAAAALKGTDVDADLAVIAVQLSDIPAETL
                     SQIKVADMGDSDSLKLGNGVIAIGNALGEGQSVTVGYISALNKEVDIEGVTKNLIQVD
                     AAINPGNSGGALLDMNGKLIGINEAKMASTEVEGVGYAIPISYAKDIIDDLMAKTTKV
                     AVAEDEQGYLGIQIQDINSQMAKAYGMPEGIYVYKIVEGLAADGSGLRERDIITKVNG
                     ETVRTAEDLQKMLTYYKGGEIVTLTVQSLDNGAYAEREVQVTLGYRKDAEKNLQQDQE
                     K"
     gene            45842..47047
                     /locus_tag="ACZPCR_04700"
     CDS             45842..47047
                     /locus_tag="ACZPCR_04700"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HIR1230205.1"
                     /translation="MNTNAVVHIKKGGARALKAGGAWIYDNEIERIEGSFENGDLATV
                     CDFDGYCLGYGFINTRSKITVRMMSRKKDSVIDDAFLEMRIRNAWEYRKAVGDISSCR
                     VIFGEADFLPGIVIDKFSDVLVVESLALGIDRMKLTIVDILKRVLAEDGIIIRGVYER
                     SDAKVRLQEGMERIKGFIGEPFDTKVEIVENGVRYLVDVKDGQKTGFFLDQKYNRLAI
                     QKLCPGKRVLDCFTHTGSFALNAGIAGAKEVLGVDASELGVSQARENAALNGLSDRVS
                     FVCADVFELLPELEQKGEKFDVVILDPPAFTKSRNSVKNAVKGYREINLRGMKLVKDG
                     GYLATCSCSHFMTPELFTKTIREAAGNVHKRLRQVEYRTQAADHPILWAADESYYLKF
                     IIFQVVDEK"
     gene            complement(47287..>47477)
                     /locus_tag="ACZPCR_04705"
     CDS             complement(47287..>47477)
                     /locus_tag="ACZPCR_04705"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230206.1"
                     /translation="FAVLPENRTGTEETTDLPLRVQNTFWYSGYVSFTAQAPDGQFTE
                     AEQTEVIAILSSFRVEDN"
BASE COUNT        11041 a        13321 c        10598 g        12517 t
ORIGIN      
        1 tcagtatggt tcatttctct ggcatttatt cagaaaaaac aattttatta acctaacacg
       61 ctcacaatct taactgggtt ccggtaggtc cagggagaga tcttaatgcc tgtccgctct
      121 gtggaggcat gtacaatctg gccgtctcct atgtaaagtc ctacgtggtt aatccggctt
      181 ccattggcat aaaacaccag atcccctggc tgcatctgct ctgcgctgac ctgggtgccc
      241 tgagtcgcct gggagcgtga ggaacggttc atgtccacgc cgccggcatg ctctaacaca
      301 tagcttgtaa atccggagca gtctgtgccg gtattcggat ctgagcctcc gtacacatag
      361 ggatttccaa ggaaggtgag ggcgtaatct acaacatcct gtctcacgtc tccggcttcc
      421 gcctccacaa ctgctgattt tccgtctgcc atcagatagc cttcctctcc gctctctgaa
      481 aagactttca cccagccgtc gccgttgtcc tcgactacct cgtaggtgtc gccctgtgac
      541 gcctgctcga ctacggcaga ctctgcgttc atctctgagt acagtgaaac ctgctctact
      601 tctactttga ctactgcgcc ctcctcggct tcagcggcct ccgccttcgc cggattcgca
      661 aataatacgg cagagcagac gcacatcatt cccaacagct tccatcctct attctttatc
      721 atcccaaaac tcctgacttt ttattttcaa tccgcaatct tacaactttc tcataacata
      781 ttaacttttt ctttctaatt gttacataat tgttaaatat gttacgacgt tattatattt
      841 actttttttt gtgctgtcaa gaaaattgga gcgatttata tttatttaat aatttcccag
      901 gggccggaat ccgctgtctg tctttaggaa atcgtctcta acagagcctc cagtctggtg
      961 gcgatctgtc cctgatcgga cttggaataa tctgtctcta tcatcagata cgggattccc
     1021 tccgcctcca ctgtacgctt gataaaatgc gcctcgatat tgtaggtatg gcaggactgc
     1081 aggataattt ccaccactcc gtctgcctgg tactcatgga tcatctcctt aatatagccc
     1141 tggcggctgt cgttaggact catcaccgag cagttgatat tcaggtattt cttcgctaac
     1201 gcgtcgaata ccggcatatt ctcgtctact tcctctacct tttccctggt tccgctgcag
     1261 gaatcgaagg ccactacatc ggctcccatc tcttccacgg tcttgataat cttatcgcgg
     1321 actcctccgt ttggacatcc tgtaatcaga agtctcggac gtttggaggt tttgccctta
     1381 tagttctcct cccagtcctt taatacctct tccgtccgct cctctacccg gcggattctg
     1441 tcttccatgt caaagttaaa tccaagggaa tcggatactg tgctgatctc atatcctgaa
     1501 atcggggacg gatacagctt tccaagctcc atgaatctca gcatggcctt cctctccctg
     1561 tttttcaggc ggatggcctt cttaatatct tcctctgtaa tctgaatgcc gtagaaatcc
     1621 tccagcttct ctttcagggc aatgatctcc ttcttccaga gatccagtcc tctctcattt
     1681 ctctgggccg gcagctgcat gacgtaagtc tccttcagct cgttcagcag ttcaaacatc
     1741 tttttctttc cgtcgcaggt cgtctccccc acaatcagat ctgcgaaata gaaatacggg
     1801 caggtatctg tcagcgcaaa gccatagctg gccttgatta acgggcagag gtttctcggc
     1861 agcttcgtct cggcagcagg gatcggctgc tcgctggaag cgcacagaga agcgttcact
     1921 acgccgcccg ccatcaaaat ttccaccggg acaaaggagc agaatatgcc tgccgttctg
     1981 gcgccctttt ccttcagttc cttcatcttc atgaatcccg cttttcttgc ctcgtcatat
     2041 gtcacaaaat tttctggcag attcatcatt ttctcttctc ctcctgaaac tacattcctt
     2101 ctgcactgta tgcatattgg tctattttat cacaatttac aggggaattc gagacaaggg
     2161 gacgcggcct gatattggtt ttttaactaa atcgagcttc ttatagaaaa catctataag
     2221 aagccctttc ttttttcttt ctctttaatc cagctccagc tttcctgtat acagctgata
     2281 gtagattcct ttttctttaa tcaattcctc atggctgccc cgctccacaa ttctgccgtg
     2341 ttcaagaacc ataatcgcgt cgctgtttcg gatggtggac agtctgtggg caatgacaaa
     2401 taccgttctg cccttcatca ggttgtccat tcccttctga acgatctgct cggttctggt
     2461 gtcaatgctg gacgtagcct cgtcgagaat cagcaccggc ggatccgcca ctgccgccct
     2521 ggcgatggct aacagctgcc tctggccctg ggacagctcc tcgccgtcgt tggtcagcat
     2581 ggtatcgtat ccctttggca gcattttaat gaactgatcc gcgtgggcca gctgcgccgc
     2641 cgcatagatc tcctcatctg tggcatccag ctttccgtac ctgatgttgt ccataatcgt
     2701 tcctgtaaac aggtgggtat cctgaagtac aattcccaga gaacggcgca gatccgcctt
     2761 tttaatcttg ttgatattaa tgccgtcata gcggattttt ccgtcctgca catcgtaaaa
     2821 gcggttaatc aggttggtga tcgtcgtctt tccggctcct gtggaaccga cgaaagccag
     2881 cttctgcccc ggctttgcgt agagcgtcag atcatgaagc accattttct cctctgtgta
     2941 gccgaaggtc atgtcgaaga aacggacgtc tcccttcagc tctgtgtagg taactgtgcc
     3001 atccgactgg tggggatgct tccaggccca gagccctgtt ctctccctgc actctgtgag
     3061 atttccgttc tcatccttct ttgcattcac aagagttaca tagccctcat ccagctccgg
     3121 ctcctcgtcc atcagacgga aaatccgctc cgctccggct aaggccataa taatggagtt
     3181 aaactgctgg gcgatggaca taaagggctg ggtaaagctc ttggtaaact gaagatagga
     3241 agccatcacg cccagagtaa tgccgccgat tcccatgacg gataaaaatc cgcccagcac
     3301 agccgtcagc acaaactgca ggtttccgat gtttccgatg acaggcccca tcatgttggc
     3361 aaaggtgttg gctctggagg cgctgacaaa cagcttctca ttgagcttgt caaattcttc
     3421 ctctgcaatc cgctcatggt taaacacctt gataactctc tggcccgtca tgtgttcctc
     3481 cacaaagccc gtcacaccgg cgatatccag ctgctggctt aagaaatact ttccgctgtt
     3541 gccgccgatg gtctttgtca caaacagcat gactccaatc ataatcactg ccagaacagt
     3601 cagaagaggg cttaatacca gcatggaaat gaaggtgacc gtcactgtga gaagggactg
     3661 gagcacctga gggatagcct ggctgatcat ctgtctcagc gtatccgtgt cgttcgtata
     3721 aagactcata atggatccgt tggtattctg gtcaaaatag cggatgggga gcttctgcat
     3781 gtgctcgaac atctcgtccc tgaccttttt taacacgccc tgtccgatgt agaccatcag
     3841 gcggctgtag ataaaggtgg cgatcacgcc gcacaggaaa atgcagccca gcacagccat
     3901 ggcccggtac agctccgtat agtttggatt ctgctttcca atcagcggga taatataatc
     3961 atccagcagg aatttcagcg aaagggacac ggagatggac gcaatggagc tcatcagaat
     4021 gcagaaaaac acgccgataa accgcagctt gtagtccctc agaacataac ctaacagacg
     4081 ttttcctgtc gtcagcgtgt ccttggttac ccttggcttt ctctgctcat tactcatagt
     4141 cctcacctcc ctttacctgt gattcgtata cttccctgta aatggcgttt gtcttcagaa
     4201 gcgcctctga ggttcccact ccgtttacct ttccattttc catgacgata atcatgtccg
     4261 cgtcctccac agaggaaact ctctgggcaa tgataatctt tgtggtatct ggaatctcct
     4321 ccctgaaggc cttccgaatg agggcgtctg tctttgtgtc caccgcgctg gtggaatcgt
     4381 caagaatcag gattttcggc tttttcagaa gcgctctggc aatgcagagt ctctgcttct
     4441 gtccgccgga cacgttgttt ccgccctcca cgatcattgt gttgtagccg gccgggaact
     4501 cctgcacaaa gccgtctgcc tgagccagcc ggcagactct ctgaacctcc tcgtcgctgg
     4561 cgttctcatc gccccagcgg atgttgtcgt aaatactgcc tgtaaacagg acgtttttct
     4621 gaagcaccat ggatacctga tctctcagcg cctccaggcc gtagcttcgc acgtcgattc
     4681 cacctacctt tacagaaccc tccgtcacat cgtaaaggcg cggaatcaga ttgacaagag
     4741 aggttttcgc gcttcccgtg cctccgataa tgcccaccgt ctgtcctgat ttaatatgaa
     4801 ggttaatgtc ctttaaggag aggtttccgc cctttcctcc gtagctgaag gacacgtgtt
     4861 caaagtcaat gtcgccgttt ggaacctctg tcacagcgcc tgccggatcc tgcatttccg
     4921 gaacctcgtc aagcacctcg ctgattcggt ctgtggaggc ctcggcgatc ataatcatga
     4981 cgaacacaaa ggttaccatg gttaaagaga tcaaaatctg gatggcgtag acgatcacgc
     5041 tggtcagctc gccagtctcc atggtctggc cgataatgct ttttcctccg atggaaacca
     5101 tcagaagaat tatgctgtac atgaaaaact gcatggtcgg cgcattccag gccacgatct
     5161 tctccgctct ggtaaacaga tcgtagacca gctttgacac gccgtggaac ttctcaattt
     5221 catgctcctc ccgcacgtag gccttgacta cccgggaagc gtttacattt tcctgaacgg
     5281 aattatttaa gacgtcgtac tcgtcaaata ccctgataaa atgaggatgg gccttctttg
     5341 caatgaacat cagaagtcct cccagaaccg gcaccagcac cagcagaatc agagaaatct
     5401 cccagttaat cgtgagaatc ataatcaggg agaggataat cataaacggc gctctggcca
     5461 gaagacggat actcatcata taagccatct gcacgtttgt gatgtccgtg gtaagccttg
     5521 tgacaaggct tgaagtggaa aaatggtcga tatttttgaa tgaaaagttc tgtatcttat
     5581 aaaaaatgtc atggcgcaga tttttggcat agccggccgc cgccaccgcc gcaaactttc
     5641 cggccatagc gccgaagaac agggcaatca tggccatagc caccagaatt acgcccatgc
     5701 ggacaatata gggcaggttt ccctgcgcga ttcccacgtc gatgattttc gccatctgaa
     5761 gcggaatcag aacctccatc agaacctcca gaatgacaaa tacaggggcc agaatggact
     5821 cccgtctgta ctctctgatg gatttaaaga gttttctgtt catggtttcc tccttctgtt
     5881 ttacttagct gtcatgtcag acggcattcc tgctctttac agtcctgctc cttgcaggaa
     5941 aggttcctgg acatttgggc cagcacctgc atacagatat ccagatcttc cctggcaatc
     6001 ccctgcagca tctgtgtttc cgcacacctg agagactgca tcacccgttc cctcatggcc
     6061 agcgccttct ctgtaggcgc cacccgcttt agacgcccgt cccgctctac gctctccctg
     6121 cagataaagc ccttcttctc caaaagctgg agaatccctg tggctgtgga tttccgaatc
     6181 tgaaactccg cctccacatc cttctgaaag atatcctggt gcatagaacc tacaataata
     6241 aagtgaagca tatgacgctg aagcatggtc agctcattgc cgtcatccgg aactaaaaaa
     6301 cgccgtttca gctgattgga taaaatattt accatccggc ctgcgctctt acagcagagc
     6361 tcaccgcttt tctctgcttc cgtacacatc ttaccacctc cgcctgcgct gatttcccgt
     6421 gttcaggacc gtttccgcct ggtttcaact ggacgattca gagcttttta aatagttcgc
     6481 tgcctaactt ttaaaagtat agtcggaaaa atttttattg tcaagagaaa aaaacgccac
     6541 aaaaagccgt ctgagcggcc tgtgattgga tgcaaacaat ataggttctg cgggaaaaat
     6601 ccaggatgtt tttgttgtgg cggggatatg gaattgatat aatacagtta taaaggaagc
     6661 ggaagtccgg aggcatatat gaaagaattt acctatgttg ctttaagaca aaaaccagaa
     6721 ttaaaagaag ctgctgcatg gtttcatgat aaatgggaag tgccgcaaga agcgtatctt
     6781 gaatgcatgg aagcatatct caatcatgaa acagaatatg gctgggaatt tttgtgtatg
     6841 gttcaagggg ataatgatcc tgatatgaca agaatgtata tccatagatg acttcctatt
     6901 taaagaagaa ttgatgcgag ggatatagac ttggaaacac ttttgtgaaa aagaaccaaa
     6961 cattccgctt gccaatgaat gaggagaata ccgcctatga aaaaagcaac cgtcatccca
     7021 actgtcagcg tcctgattgc tctggtttgc gccgctctgt tttgcttgaa ctggaacccg
     7081 gaaccgcttc tgaaaggaaa ggaacagccg gtgacgctga gcgatataga acaaaatctt
     7141 acaaccgatt ttaacggttt cccagccggg gaggatattc caaggctgac cagtgcagag
     7201 gacttttcag aaatcatcta tttgtcagat tatgtgaccg cggaaccagt ggggattgtc
     7261 gaaaccggta tttccagcct gaaaccatgg gaagatcaat attatacgca aagagtcaag
     7321 ggcagagcaa ccggacgtca aatccgtcag ccggaaatca cttcatctgg cttggatttg
     7381 ctgggcagct atcagccata ttacctgttg gagcttccgg atcatactta tatcgtggca
     7441 caaattccgc cgcaaacagc gaaggcaatc gaaaagggcg aaagcatcac acttcctgtc
     7501 ggtgagaagg taagtatgac aaatgccgcc cggaacgaac tttctgctat ctgcgaggaa
     7561 tatggaactg atatggacgg tgtgttctat gccgttaatg acaaatggca ggaggagcat
     7621 cagttcatct tatttctgct gcgcttcgga gctgccgctc tgatctggtt tgtacttgcc
     7681 gcgggactga tgctggccgg gtggaagctg ttcaaatgcg atgaaggata aaaagcggag
     7741 ggattgagga tatttttatg aatgaattgc aaaaaagatt ttttgaatat ttggctgcag
     7801 tacaagaaac atgcgtagag gtctgcatga ttcagcataa atgtgacgat gaaaaaacaa
     7861 aacgtatgct gtacgatgtt acctttgagg caatcacagc aattatggaa atgattgatg
     7921 gttattccgc cttcagcggc aataagcatg atattgtcaa cacagttacc ggagaacatt
     7981 taaaagaaaa tccttttatt gaattacatg atcaagcggc gggatttttt aaatacgaat
     8041 agcgcccgtg tgcaagtagc agccattcca gctttactgc ttctatctct gcttcatctt
     8101 cttgctctgc gggcaggaag catccctcgt tttcagttcg gtcattttca gcccagtcaa
     8161 ttactgcagc gccgtcccta tagccaggtt cgccgctccg cacaggcaca taaccagaat
     8221 gggattccac tttctcgtcc gaagcagcag gaaggccaga aggaacagcg cggcgctgat
     8281 cacgtctaaa tttccaatgg acgccgcccg gccgttgaat actgccgtat tcagcatgga
     8341 aaggccggcg gcggctatca gagccacgac ggcagggcgc agggaggaca tcacggagct
     8401 gacaaaggaa ccgcccttgt atttataata gagaaacgcc agaaaagaga caatcagaaa
     8461 agagggaaaa atacagccca gagtggctgc agccgcacct gatattcccg caattctgat
     8521 tcccacaaag gtagccgcgt taatggcgat ggggccgggc gtcatctccg caatggtcac
     8581 taaattggta aattcatcca tcgtcagcca cccgcaggct tctactgcct ggctctggat
     8641 cagcggaatg gccgcatagc cgcctcctac actgaacatt cccaccttta aaaaactgaa
     8701 aaaaagctgc aaataaatca cagggagccc tcccttcctt ccttatcttt cttctgaagc
     8761 acagctcgca aaatcccggc gccagccgcc gccagaataa tatagataac gtttactccc
     8821 aggaataaat cagcggcaaa ggctccggcc agaatcagat tcagatacag gctctttttt
     8881 ttcaccatgc cttcccctaa atcccaggcc acatccagaa tcaccgccgc cacgcctgcc
     8941 tgcattccct tgagggcgag agccacaaag agattcgagg aaaaagcgct gtaaaaaaac
     9001 gaaaccacag acaaaataat catagggggc agaatcgtcc ccaaaaccgc cgccgccatc
     9061 ccggcagctc cgcagatttt aagtccaact aaaatcgccg cgttcacggc aatcgccccg
     9121 ggcgacgact gggccagggc tgtaaaatcc agcatttcct gctcgtccag ccagtgaaga
     9181 gtgtccacaa atttccgctt cataaaggtg acaatcacaa agcctccccc aaaggtaaaa
     9241 gcgctgatat aaaacatgcc tgaaaacaga agccacagcc ttctccagcg cggctccctt
     9301 ctgccatttt cccatccctg tcctgtctct aacggtttct cttccatcct gctcctcccg
     9361 gccgcctgtc catacccgcc gccgtctatt cgtatatatt ttccttatta tatagaagtt
     9421 tccggtgaaa tacaatcacc ttcacggcaa acgctgaacc aggcgaaaac ttttctattc
     9481 ttcgatctgt ttctgtaata tttcgctata tatgtaacaa tccgtttact ttttcaaaca
     9541 attttgatat tattagttta atattcaatt gacatttctg acggaaagaa aggagctttc
     9601 attttgagca gacttagtat tgtgaccacc agcagagctc agaccgttgt ggaagggctt
     9661 tataaagatt tggagcgccg gatcatcgcc agccctccag gactctgccc ggtggattta
     9721 accgcatcat ttctgaaaat gtgtatggcg cagacctgcg gaaagtgtgt tccctgccgg
     9781 atcgggcttt cccagctgga cctgctgctg aacgatatct tagaggggcg tggaaccctg
     9841 gacaccttaa atctcattga aaaaacagcg cgcgttatct cctcctccgc cgactgcgcc
     9901 attggctacg aggccgccaa catggtgtta aaggggcttt ccggcttccg ggaggatttc
     9961 ttaaatcaca ttgaatcgaa ccgctgtctc tatcatctgg atcagccggt tccctgcgtg
    10021 gctctctgtc cggccggcgt ggacatcccc ggctatgtgg ccctggtggc tgccgggcgc
    10081 tacgcggacg ctgtgcgcct gatccgaaag gacaacccgt tccccaccgc ctgcgccatg
    10141 gtctgcgagc acccctgcga gtcccgctgc cgccgcaata tgattgacga cgctgtcaat
    10201 atccgcggca ttaagctggc ggctgtcgac aatgcgggca ttgtgcctcc gccgccctgc
    10261 gctccttcca ccggaaagag gatcgccatc atcggaggcg gccccagcgg cctgtctgca
    10321 gcctactatc tgcagctgat gggccatcag acaactgtct acgaaaagcg ctccaagctg
    10381 ggcggaatgc ttctctatgg cattcccagc taccgtctcc ccagagagcg gcttcaggag
    10441 gacgtggacg ccattctggc cacaggcgta gaggtgaaaa ccgacactgc tgtgggaagc
    10501 gagccaggac aggtttccat ggatttcctg cgcaaagaat acgacgccgt ctacatatcc
    10561 atcggagccc acactgacaa gaaggtgggc attgagggcg aggacgccga gggcgtcatc
    10621 tccgcagtgg agatgctccg ggaggtagga cgcggaagaa tgcctgactt taccggcaag
    10681 cgggtctgcg tcatcggcgg cggaaacgtg gctatggacg taacgcgctc cgctatccgt
    10741 ctgggcgcct cccacactac ggttgtatac aggagaagaa aggacgatat gactgctctc
    10801 ccggcagagg tggagggcgc tgtggcagag ggcgcagaag tattggagct ccacgctccg
    10861 gagcggattg agacagatga gaacggacgt gtagccgctc tctgggcttc cccgaagatg
    10921 atcggactca taaaggacgg acgcccctcc cccgcttcct ccggcgagaa tccggtgcgc
    10981 attccttgcg atatcgtaat cgtagccatt ggacagggca ttgagacaag acactttgag
    11041 gacgccggca ttccgattaa gcgcggcgtc attcaggcgg ctaactggag cgctgtagag
    11101 cacgcgccgg gcgtatttgc cggaggcgac tgcgtgacag gacctgccac tgtaatccgg
    11161 gccattgcag ccggaaaggt agcggcagcc aatattgacc agtatctggg ctttgaccac
    11221 attatcagcg tggatgtgga tattccggag gcagacttct ctgaccgtcc gccctgcggc
    11281 cgcgtaaata tgaaggagcg ggatgcaaac gagagaaagc atgactttga tttggcggaa
    11341 tgtccgatga gcctgaaaga ggcggatcag gaggctcacc ggtgtctgcg ctgcgaccgc
    11401 ttcggatatg gaaactttaa aggaggcaga acaacagaat ggtaaactta acaatcaata
    11461 aacagcacgt ctgcgtcccg gagggaacca ccatcctgga ggccgccaga cagattggaa
    11521 ttaaaattcc caccctttgc ttcttaaagg aaatcaacga aatcggagcc tgccgcgtct
    11581 gcatggtaga gatagcaggt atcagccgtc tcgtcactgc ctgcaatacg ccggtgacag
    11641 aaggcatgga ggtgattacc aacagcgccc gggtccgcga ggccagaaaa accaatgtgg
    11701 agttgattct ctcccagcat cacactgact gccctacctg cgtcagaagc ggaaactgct
    11761 ccctgcagaa gattgccaac gacctgaacc tggttgccaa cgaataccct gtccgctatg
    11821 cagagacaaa gtggacctcc accttccccc ttgtaaggga cgcaggaaag tgcatcaaat
    11881 gtatgcgctg cgttcagatc tgcgataagg ttcaaagcct gaacgtgtgg gacgtttcca
    11941 acacaggttc ccgcactacg gtggacgtct ccatggggcg ggagatcaaa atgtccgact
    12001 gctctctctg cggccagtgc attacccact gtcccacagg agctcttcag gagcgggacg
    12061 acgtttccag gattttcgat atccacggag atctcagcaa tcctgataaa atcacagtgg
    12121 ttcagatcgc cccggctgtc cgggccgcct ggggagaaga attcggcctc tccagagatt
    12181 tcgccacaga caaacggatg gtggccgctc tcaggcgcat gggctttgac tatattttcg
    12241 acaccacttt cagcgcagat ttgacaatta tggaggaagg cagcgaactg ctggagcgtt
    12301 taagccataa ggaagattac aaatggccta tgtttacctc ctgctgcccg ggctgggtac
    12361 ggttcttaaa atcacagtat ccggagatga cggatcagtt atccacagcc aagtctcctc
    12421 agcagatgtt cggcgctgtg acaaagagct atttcgccgc ccggctgggc gtagatccag
    12481 gcagcgtcac ctgcatctcc attatgccct gcgtagcgaa aaagcaggag gcagatctgc
    12541 ctaccatgta tgacaacggc ataaacggcg gaatcaagga cgtggactat gtgctgacca
    12601 ccagggaaat ctgccgtctc attaaatcag agcagatcga tgtggcttcc cttccggagg
    12661 aggaattcga ctctccgtta ggtgaaggtt ccggagccgg cgtcatcttc ggcgctaccg
    12721 gcggcgtcat ggaagcggcc cttcggacca gctacagcat tgtgacagac aaaaatccaa
    12781 agcctgacgc cttctctaac gtgcgcggca tggacggctg gaaggaagca gaattcaagc
    12841 tgggaggcac tgttttaaag acggctgtgg ccagcggcct gggcaatacc agaaagctga
    12901 taaacgccct tcagaaaggc gatgtgagct atgatttcgt ggagatcatg gcctgtcccg
    12961 gcggctgcgc cggaggcggc ggacagccga ttcacgacgg aaaagagctg gctgaacaga
    13021 gaagctccaa gctttacgcc atggatcaga aaaatgcagt ccgcttctcc cacgaaaacg
    13081 aggaagtccg ggagctgtat cacaattact tcggaaagcc tggatcccac ctggcccaca
    13141 agctgcttca cacagaccac aacggctggg atatgccgtt aggaggaaaa taacagaaaa
    13201 tagcaaaagg gcagaagcaa tcgtttccct gttccactta aagtcactgg aaacgattac
    13261 ttctgcccct gttattttat gtgcaaaaca ctattccctt accagcaccg cctcgatgct
    13321 tccaatgtac atggtgtggt aatttttatc tgcgtaccac ttctcatcat tttctttcac
    13381 atcaaagccc tccggcccca tgtactgatg atactgcttg cggcagacga aaatcatctt
    13441 cgcctcctca aaggctgttg ttccgtccac ctccatggga gtcaggcctg cctcacggat
    13501 cttatcctga tctcttccgg aaacctttcc gcacagattc agcgccgggc ggaaggactc
    13561 gtcaaataca gataaggtaa acagctcctc tctgtccaca aactcttttg tgtagcggga
    13621 ctggcggata taagcggttg cagacggctt tccccagatc acgcccaaac ctccccagct
    13681 ggccgtcatg gtattgcatt ccttctcagt tcctgctgtg atgagaaacc agtcctttcc
    13741 aatgacagtg aacggattga cagacagttc ctcaggcttc acacgtttaa acggcatcat
    13801 tgattcctcc tttatcttcc cctcatattt ctcagcagcg acacaaccag aagcacaatt
    13861 aaaatcggcg ttgcaaagcg aaacagaata gcgaaaattc cgcccactat ggacagcact
    13921 gtaaacagca ccagacacag cactgcaata atcagggcct tccagtacca tttgttcaga
    13981 ttcacatagt gaaacctgga atatccgccc tggccggatc catagcttcc agacgcgctt
    14041 cctgcgcctc catagctgcc ggaagaagag ctttccccgc tctcatagct gccagagcct
    14101 ccgctggtat ctataatcgt tctggcaatc agcctgggac ttccaatctc ctctatcacc
    14161 tctgcctctg aacgcccctt ggacgtctcc tgggaaatgt agttatcata gtagcggagg
    14221 ttttccgctg tcagttcagg agaaacctct cctttcagag cagcctccag ctcctttaaa
    14281 aattctgttt tcttcatata aattgcatct cctaaatgat atcctgcgtt tttccttatg
    14341 cgttctgtcc agttgatttt ctgacaggat tatagtacca tattatcgtg aaaaaaggaa
    14401 gtttcttcac aataaacgcg attccaagcg tagccgttct taaggaggaa atacgatgaa
    14461 catgaaacat gaatccagtc ttccctgcga gcagctgtat gtgttcggca caggaaacgc
    14521 tgctgtcact cattgctata atacatgctt tgccatccgt acagagacac agcctggaca
    14581 gaccgaattt tttatggtgg acgccggagg cggaaacggt atcctcggca tcctggacca
    14641 gatgcaggtt cctctcacac agattcacca tatttttgtc actcatgagc acacagacca
    14701 cattcttggt attgtgtgga tggtgcgcat gatcggaaca cagatgaaaa agggagccta
    14761 cgagggaacc ctttccattt actgccatga cggcctggtg gaaaccatca agacgctctg
    14821 ccgcctgact cttcagaaaa agttctgcga tctgattggg acgcagattc tcctgatccc
    14881 tgtaaccgac ggggaaacca gggatatcct cggttatcct gtcacctttt ttgacatcca
    14941 ctccaccaag gcgcgccagt tcggcttcac tacagtgctg aaaaatggaa agaaattcac
    15001 ctgcacaggg gacgagccgt ttcaggaact ctgtcttccc tatgtggagg gcagctcctg
    15061 gcttctccac gaggccttct gtctctacag ccagagagag cagttccacc cttatgaaaa
    15121 gcaccacagc accgtccgcg aggcctgcca gctggcagag cagctttcca tcccaaatct
    15181 ggtgctctgg catacagagg acaaaaacct ctcccagaga aaatggctgt acacggaaga
    15241 gggaacagaa ttctactccg gacgcctgat tgtgccggac gacagagaaa ttattccgct
    15301 gtagaagtcc cctcatcctc tctggcacag acggctgccc ggctgtcctg attcttctct
    15361 tctgccccct gttccaggtg atagaaggtc atggtcgtgg ccgctatcag agcgtccgta
    15421 tcgtcgaata cctggcagtc acagacggaa aacgtctttc catgctttac cgtcctggcc
    15481 acggccgtga tcgtgccctc cggctttcca ggtcttaaaa actggatgct gccgtttact
    15541 gtcgtcaccc ggcagccata tcccataatg gcggtgccgg acaccgtgtc tgccagtgaa
    15601 aagaggcagc ccccatggat gattcccaga ggattcaaat gaagcttttc tgccttcatc
    15661 tctcccctgg cccatccggc ccctctgtct acaatcttaa ttcccagagc cgtgcggaaa
    15721 tccggctcct ctgtgttctg tctgttctct tttacatgtt ccattttttc tttttccttt
    15781 ctgcctgtca taactgtctt cctgtcctca tatgatccta ataaacatcg tttgccgttt
    15841 gtccggcgca tgattggagg gatatgtgtg cgaaacatat ggaaacggat ttctgacgcc
    15901 tatgagagga ttttattatt tttctaccga aaacgcattg tttttcttat atcagccgag
    15961 gcgctggccc ttgccgccct tacgggatgc ctgctgttaa aagcgtatcc ccgctcccct
    16021 gccgcctcct gtctgctgtc cctcctctcc cagcaaagta tcggggcagc cggatcggac
    16081 tcccggaagg atgattttat caagtgggta gattttaata ttccggagga agccatgaca
    16141 aaggccttcc ggctggacgt ggccacctgc cagcagcagc ttcatctaaa ctggattgag
    16201 cttctggctt ttctgggagc caggtatgga ggcgatttct ccagctacct ggaagccgac
    16261 atggatgaac tggccagccg tctgcagagc ggcatttcca tggagcagct gacagctgat
    16321 atgaaatatt atccctacta tctggaggcc tacacagccg ttctgggggg cctggtggga
    16381 tattatgaaa tccagatccc cgcctcagag gctccctcct tcgccctggc cgactccaca
    16441 atccaggagg acgatccctc ctgcggccct tcctctgttt cccaaggcgg cgatcccggc
    16501 gcagctggtg aaaaccatcc ccagtccggc cagaatcctg aaaaggtctg ggttactaaa
    16561 tatggcatga aggggtttct tcccattgcc aaggggtttc cctacaccga ttacgacgat
    16621 ttcggcgttt cccgctccta cggctataag agaaagcatc tgggacacga catgatggga
    16681 cagactggca ctcctgtcat ggctgtggaa tccggctatg tagaaaccat gggctggaac
    16741 cagtacggcg gctggcgcat cggcatccgc agttttgaca agaagcgtta ctactactat
    16801 gcccatctga gaaaggatta cccctatcag agctgtctct ctgaaggaag catcgtcact
    16861 gccggggatg tcatcggata catgggccgt accggctaca gctccacaga aaataccaac
    16921 aatatcgcca aaactcatct tcacttcggc cttcaactga tctttgacga atcccagaaa
    16981 gaaggaaacg gggaaatctg ggtcaactgc tacgagctga tgaaatttct gagcatcaac
    17041 cgctcggaag cggccaaaaa agaggggaca aaggagtggg agcggatcta cggcatgaag
    17101 gaccctgctg tggcagaagc agaacacagc cggaatcctt agccagaaat aaaaaatgcg
    17161 ccaggtgcat ttttgcgccg ggcgtatccg ctgacagcaa acagcagcag tcgggccgta
    17221 aggccctgtc tgctgctttc tctgcgtttt cctattgccg tttcgcgtat acgcgtctgt
    17281 ttccacaggc gctactgaat cacccgcacc cgcatcattc ccttgattcc ttttaatttc
    17341 tccagggtct cctgatccac ttttgtctcc agatcaatca tggtataggc gtatttttcc
    17401 cggctcttat tgaccatgtt ggcgatattc atgtctgtgg cggccagaat ggcggaaatc
    17461 tgtccgatca tgttcggcac gttcatgtga agcagcgcca cccggttcac cgaggtgcac
    17521 actcccatat cgcagtccgg ataattgaca gaatggcgga tatttccgtt ttccaggtag
    17581 tccatcagtt ccttcaccgc catcacggcg cagttgtcct ccgactcctc tgtagacgcg
    17641 cccagatgag gcgttgcaat tacatgttcc atttccatga cagccggatt ggggaagtct
    17701 gtcacatacc tctttacctt tccctcagcc agggccgcct tcatatctgc gtcgttcacc
    17761 agcagatctc tggcaaagtt taaaatcact actccatcct tcatctttgc catgctttcc
    17821 ctgttaatca tgcctctggt agagtccaga agcggcacat ggacggtaat gtagtcgcac
    17881 tggctgtaga ttgtgtccac gtcggtgatg tggcgcacgt cccgggaaag catccaggca
    17941 gcgtttacag agataaacgg atcgtagccc agcacttcca tgcccaggcc ggcggcggcg
    18001 ttggctacct ccgccccaat ggcgcccagg ccgatgacgc ccagcttctt gcccttgatc
    18061 tcgtttccgg caaaggcctt cttggccttc tccatatcct tggaaatatt ctcgtttcca
    18121 gcgttttccc tgcaccagtt catgcctccg gccacgtctc tggcagccag cagcattccg
    18181 gctaacacca gctccttcac gccgttggcg ttggctcccg gcgtgttgaa cactacaatt
    18241 ccgcagctgg cgcactcgtc cagcggaatg ttgttgactc cggctcccgc cctggctact
    18301 gcccgcagat tctcggaaaa ttccatgccg tgcatggacg cgcttctcac cagaattccg
    18361 tccgcctccc cggcgttctc cgtcatctcg tatccctctg tgaaaagccc tgttccgtgc
    18421 tcagaaatcg ggtttaagca gtgaatcttt ctcatattca tttcctccct ggctgtccaa
    18481 tcagctgttc ttcctctcaa attcccgcat aaattccacc agctttgcca ctccctcttc
    18541 cggcatggca ttgtaaatgc tggctctcat tcctcccacg gttctgtgtc cctttaagtt
    18601 tacaaatccc gcctccttgg cttcctttat aaatttcgcg tccatctcct ccgatccggt
    18661 tacaaagggc acgttcatca gagaacgatc ctgtttctca accgttccct taaacagctg
    18721 gctctcatcc agaaaatcat agagaagctt tgcctttctc tcgtttttct ccttcatggc
    18781 agccagaccg ccctgctttt tcagccactt aaacaccttt ccgcagatgt agatacagta
    18841 ggtgggcggc gtgttgtaga gagaatcgtt gtcagcgtac gtcttgtagc ggagcatggt
    18901 aggcgttccg ggaaggacgt cctctgtgat cagatcctcc ctgacaatgg caatggccat
    18961 tcccgcaggg cctacgttct tctgcacgcc tccccagatg attccaaatt tagacacatc
    19021 taacggttcg gacaggaagc aggaggacac gtctgccacc agagtctttc ccttagtatt
    19081 gggaagctct ggaaacctgg ttccgtaaat ggtattgttc aggcagatgt atacgtagtc
    19141 tgcgtcctcg tccaccggaa gatcggagca gtccggaata tagctgaagg ttttatcctc
    19201 gctggaagcg atggcatggg ccgttccata catctgagct tccttaaatg ccttcttggc
    19261 ccactggccg gtgataatgt aatctcccac cttatttttc atcaggttca tgggaaccat
    19321 ggcaaactgc atgtgtcctc cgccctggat aaacagtacc ttataattat cagggatctc
    19381 cattaaatcc cgcagatcct gctccgcctc cttgagaata tcctgaaagt ccctggagcg
    19441 gtggctcatc tccatcactg acatgccgca gcccctgtaa tccatcatct cttctgacgc
    19501 ttccctgagt acctcctcag gcatcacggc tggacctgcc gaaaaattgt agactctgct
    19561 cataactgct cctccttcta tctattctct ttctatctgt cagcgcctgt atctgccggc
    19621 actattttcc ttcaatcatc agatcaatct cgtcaaaggc atcctcaatg ggctttcctg
    19681 ccggaaccat cggaaatacc ttgtcatcac agccaatctg gcagtcaatg acaaccggaa
    19741 tatttaactc caccgcttcc ttaaataccc gttcaaactc atccttctct gttacccgat
    19801 aggcctttgc ccccagtccc tccgccactt tgacgaagtc tacctggtca tccagcacag
    19861 tctgggaata acgctttcca tagaacaggt tctgccactg gcgcaccata cccagcacat
    19921 gattattaaa tacaacctgg ataatcggga tattatatct ggctgctgtg gcgatctcat
    19981 tcatattcat gcggaagcat ccgtctccgc caatattcac cactgtctta tctttgcagc
    20041 ccatcttggc tccgatacag gctcccagac cgtagcccat agttcccaga ccgccagagg
    20101 acagaaaagt tcttggcttt ttatatttat aatactgagc cgcccacatc tggtgctgcc
    20161 ccacatctgt ggtaataatg gcctccccgt ctgtcagctc atagattttc tccatgatat
    20221 acgggccggt cagctgctcc ttgttatagc gcagcggata catatcgcgc attctgtcga
    20281 tatgggcaat ccactcctca tggttcatag gatccagcct tgcattgagc cttcttaaaa
    20341 tcaccttcag atcgccgatc acgctggccg tggtgtggat gtttttattg atctccgctg
    20401 gatccacatc cagctggaga atcttggcgt tcttggcaaa gcgggaggaa tctcccacca
    20461 cccggtcgct gaatctggcg cctgccacaa tcagcagatc gcactcagct actccgaagt
    20521 tggaggtctt cgtgccgtgc attccaatca tgcctgtata cagctcgtca gtgccgtcaa
    20581 aggctccctt tcccattaag ctgtcagcca caggggcctg aatcttgtgg gcaaaggcct
    20641 tcagctcctc ggaagcgttg gctgacacag ctccgccgcc tacgaagata aagggcttct
    20701 gagaggcgtg aatcagggac agggcccgct ccatgtcctc ctctgtgatc gtgtcagaca
    20761 ggggcttcac cggatctggc tgcttatatt cataatcgca ctcagccgcc gtcacatcct
    20821 ttgtgatatc caccagaacc gggccgggac ggccgcttcc ggcaatttta aaggctctcc
    20881 ggatcacgtc cgccagcttc gtcacatcct ttacaataaa attgtatttc gtgataggca
    20941 tggttacgcc taaaatatca atttcctgaa agctgtcctt tcccagcagg tttaccccca
    21001 cattacaggt aatagctact actggaatgg aatccatata ggcagtagca attcctgtta
    21061 ccaggttcgt ggcgcccggg ccggaggtgg ccaggcacac gcctactttt ccggtagccc
    21121 tggcatatcc gtccgccgcg tgggaagctc cctgttcgtg ggaggtaagt atatgtgtaa
    21181 tctcatcctg gtgcttgtaa agggcgtcgt aaatgttcag aatcgaacct cccgggtatc
    21241 cgaatactgt gtctaccccc tgctccttca ggcactcgat gactatttcc gctccattta
    21301 atcgtttcat ctgcgttcct cgctttgcct tgctttttcc gcctgatcgt tcggttttat
    21361 cttttaattg tttctaatcc tgtttctttc ccggaatttc cagtacagct cctctgtttc
    21421 cgctggtcac catggacgcg tagcgggcca gatatcctgt ggttaccttc ggctctctgg
    21481 gctgccattt tgcccgcctt tctgccagct cctcgtctga taccagcacg tttaaggagt
    21541 ggttgtcaat gtcaatggaa atcatatcgc cttcctctac cagggcaata tttcctccca
    21601 cggccgcctc aggagacaca tgtccgatgg aagctcctct ggacgcgccg gagaagcgtc
    21661 cgtctgtaat cagggccacg ctctctccca gtcccatgcc ggcgatagct gaagtcgggt
    21721 tcagcatctc tctcatgccc gggccgccct tcggtccctc gtagcggatg atcaccacgt
    21781 ctccgggaac gatctttccg cccttgatag cagcgatagc gtcctcctcg cagtcaaaga
    21841 ctctggccgg tccctggtgc tttaacattt ctggagcaac ggcggatctc tttacaacgg
    21901 ctgtgtcagg agccaggttt ccgcggagca ccgcaatgcc gcctgtagcg ctgtacggat
    21961 tctcgatagg acggatcagc tctggattcc ggttcacgca gccctcgatg ttctctccca
    22021 ccgtctttcc tgtaactgtc atgcagtcca ggttcagaag attcttcttg gacagctcgt
    22081 tcatcactgc gtaaacgccg cctgcctcgt ttaactcctc gatataggta gggcctgccg
    22141 gggccaggtg gcagagattc ggagttttag cgctgatttc attgaccaga tccatgttca
    22201 gatccacgcc cgcctcgtga gcgatggccg gaaggtgaag catgctgttg gtggagcagc
    22261 ccagagccat atcgacagtc agggcgttta agaaggcctt ctccgtcata atgtctctcg
    22321 gacggatatt tttctcatac atctccatca ccttcatacc ggcgtgcttg gccagcttaa
    22381 ttctctcaga gtagacagcc ggaatggttc cgtttccgcg aagccccatg cccagggcct
    22441 ctgtcaggca gttcatgctg ttggctgtgt acattccgga gcaggatccg caggtcgggc
    22501 agaccttgtt ctcatactct gtcagctcct cctctgtgat gttcccggcc gcataagcgc
    22561 ctactgcctc gaacatgctg gaaaggcttc tctttctgcc gcctacatgg ccggccagca
    22621 taggtccgcc gctgacaaat acagtgggaa cgttcactct ggctgctgcc atgagaagtc
    22681 ccggcacgtt tttgtcacag tttggcacca tgacaagggc gtcaaactgg tgcgccagag
    22741 ccatacactc cgtagaatcg gcgatcaggt ctctcgttac cagggaatat ttcattccca
    22801 catggcccat ggcaattcca tcgcagacgg caatggccgg gaataccacc ggagttcctc
    22861 cagccatggc tacgcccagc ttcacggcct ccacaatctt gtccaggttc atatgtcccg
    22921 gcacaatctc attgtaagag ctgacaatgc ctaccatcgg ctttctcatc tcctccggcg
    22981 tcatgccaag ggcgtttaac agggatctat ggggagccgc ctgggggccc tttcttactg
    23041 cgtcactttt cataattttt tctccttctt aatttaatct atgtatggaa gatgctgccg
    23101 gaaagcgcca ggctctcagg cagcttgatc agatacttta cttaatcctc tcacagatca
    23161 ggcgtcccat ctcttctgtt cccacctgaa cgcatccttc cgccataata tcggcggttc
    23221 tgaaatcttc tgtgagcacc tgctgcacag ccgtctccac agcggccgct tcctgatcca
    23281 ggtcaaaaga ataccggagc atcatggctg cggacaagat cgtggcgata ggattggcaa
    23341 ttccttttcc cgcaatatcc ggcgcggagc cgtggctggg ctcgtacagg ccgaacctgc
    23401 tctcgttcat gctggctgag gaaagcattc cgatagatcc ggtgatcatg ctggcctcgt
    23461 ctgataaaat atcgccgaac atattttccg tgagaatcac gtcaaactgt cccggattca
    23521 tgaccagctg catagcgcag ttgtctacca gcatatgggt taaagtcacc tcgggataat
    23581 ctctggcaac ctcctccacc acctttctcc acaatctgga ggaatccagc acattggcct
    23641 tatccacgct ggtcacatgc tttttcctct tcatggcaat gtcgaaggcc ttcactgcga
    23701 ttcttcgaat ctcgttttca ttgtaagtga gagtgtccac agctgtcgcc acgccgtcca
    23761 cttccttggt atagcgttct ccaaaataca gaccgccggt cagctcccgc ataatcacca
    23821 tatcgaatcc gtccccgata atctccttct ttaacggaca ggcctcggag agttctttgt
    23881 aaaggtaagc tggacggata ttggcaaaca gccccaggcc ttttctgatg gcaagcagac
    23941 cggcctccgg cctcagattc ggcgccacat cgtaccatct ggagtttccc acatttccgc
    24001 ccactgcccc cagcaggacg gaatcactgt ttttcgccgt ttccagagct tcctcggtta
    24061 aaggaacgcc gtatgtatcg atggaaattc cacccatcaa aacctctgta tactgaaatt
    24121 tatgcccatg gaccgctcca acccggtcca gaaccttgca ggcctccctg acaatctccg
    24181 gcccaattcc atctcctgga attactgcaa tcctgtaatc catcctgtct cactcctccg
    24241 cttttctggt ttctttccat catatcctat ttgtctgtat ttttcaactg cgcggccggg
    24301 atttacagga aaccttctat ataaatttgg aattttttgt ataaccggag gttatcgaaa
    24361 tttctgtcgc atatcgaatg acatgcaagt gtggaggctg gtatgtgaat gaggggaaac
    24421 atccatcctt tataatttta tcagattttc atatagagaa agggtaccgc agctacatct
    24481 ctttggatga ttctgtggta ccctctttcc ctcttactta tttctgccag aactgctgca
    24541 cagactgctt cgccgccttt atgagcattc ctacctcact gtcacagctg aataaattca
    24601 ttcccagttc tctgcaggaa tgaatcagcg tcttttttga tgtaataatt cctgacgact
    24661 tgcctgcgcg agctgcttct tctgcagcaa gctctgctgc ctttaatatc tcttttgact
    24721 ccacctgccc cggcattccc aagtcagcgg ccagatcgtt aggccctatc atcagagcat
    24781 ctaccccttc cgtttctgca atttccctaa tatggccaag agcctctctg gtttccaact
    24841 gtaccataat cattgttctc tggttagcca ttttgagata ctcttcaaga ggcggcggag
    24901 cgtagttcgt atgagctctc tgcgtagata tcccgcgctt tcctaaagga gtgtatttcg
    24961 catattccac tgcctgtctg gcatcctctg ctgaattgac cataggaacc agaagaccgg
    25021 cagctcccat atccattacc ttggtaatat actctcttcc tgttgacgga acacggacaa
    25081 agacaggcag tccgcagcag cttcccattc caatcagcgc cgctgtctgg gataggtcga
    25141 aataaccgtg ttcgcagtca ataatgacaa actcaaagcc tgctgtcttt aaaattctca
    25201 caatattcgg ctccgccagc tctgacagca tcgtgcccag cgtcagttct ctgtttgtaa
    25261 ctttctgttt taactgctcc atgctctctc cttatccttg caatatcagc tctggatgtt
    25321 cctccggcgt ctggcagctc ccttcacaga ggagagcaat cctgtaaagt ccatttaagg
    25381 cctcgtccgg cacagcagac agcgtacaca gttttcctga acgttctcca atctttttca
    25441 ggagttctgg cctcttccaa gatacgcctc cagcgcagac cagcctttga atctcctctt
    25501 cttctgccag tttttttata tgctcccagt aggtgtccgc catattttca aaagcagccg
    25561 caaatagatg ttctgtattg aggtttacat ttgtaatacc tctgatttct cctccctgac
    25621 gcttgtccgg aagagcgtaa aagctcatat ctgctaaaag cccgtctgcc tgcccatcgt
    25681 acccttgaag agccgccttc cacaaatccg tcttctctgc cttttgccct gacaggcgct
    25741 gataaaattc tcccaggaaa tctatcagaa cgtccagatt tctccctgac ggcatattag
    25801 aaattgtatt aatatactga tttccaaaat acggcctgat ttcataggga cctggacgaa
    25861 attctttggt agtgacagat acctgagaag cagtggcaat gttaatcacc gcatcccgct
    25921 gcctcgtcat actgcccaga atcgcgcact gctgatctcc aaaatctgga tataccggga
    25981 tttctgttcc cttatagctc caaaaaccac agatttctgt atcgctctct gccagtttcg
    26041 gaagccgtat ctggtgaaac cctagcctct ccaaaagcgg cttatcccag cagcagtttt
    26101 tcacatctgc cagtcccagg ggagctgcat tcattatgtg gcatcgattt tcccctgtca
    26161 gccctgctat aatataagag cccagagtga acagttctcc gtctcttgga agatcctctt
    26221 cttccagaag agtataaaga ttgcaaagcc ccagagacgg ctttatatag actccatgat
    26281 tttccatgtc ctggcggctg atatcagcag ctaaagagtc catgtatgtc tcctgttcat
    26341 tttttctgtc cagacagcgc atatcctgcc atgaaatata ccgatcctcc cgcccctctg
    26401 tgcaatagac aaagccatgc atttgagtag acagaatcac gccttttatg tcctcataaa
    26461 gatccgcaaa acactccgcc tgggttctga ccatagcgag gagttcttct gctgaaatct
    26521 caaagcagcg cctgtttttt aactcccttt tcgcaggggc gggaaagcgc tgttcctgcc
    26581 tggccttccc cgcctccata tcaatcagga ctgattttac ataggtactc ccaatgtcaa
    26641 ttcctatata atacatcccg tctcctccct gcttacagct gctttaaatg aattgcaaaa
    26701 ccgcctatct caccttccag gtaaacgacg ctcaaagagt tgtcttcacg gtaaacagct
    26761 gtgctcatat cccgcttcaa tcctctttcc tctaagtaat tcagagccgc ttctatgtct
    26821 tccacaccat aagccagatg tcccagacgc cccagatagg gttttttcat aatttctaca
    26881 cttgtaccag caaacagaga gctgggattt tcagaaatat caaatcccat ggcctggcta
    26941 aattgctctg ctgtcttttt agcctcttcc ccatcaacac agttgatccc cacatggaga
    27001 agcttaaatt ctactttttt attttccata acgcctgctt ctcttttcca ttatcttgcc
    27061 tgtttttctt tatttagacg cttctaacgc attcataaat gccgtatata cagtctcgcc
    27121 gcagtctgcc ttaacctcgt cccacactga agctgtagcc tctgcaaacg gagccagctc
    27181 ctccggagtc aaatcaataa tttctacgcc tgcctctgtt actttcttct ccagctctgc
    27241 gttattctct ttatagtaag aaacagatcc ttctaccgct tttttcgcgc cctcgtcaac
    27301 tactgctttc aaatcatccg gcaggctgtc atagtagttc ttgttcatga tccatacaag
    27361 attctgaggc agatgacgcg tctcaatcac atatttctgc tgctcataaa atttctgagc
    27421 atagaccagc tctaaaggat tctcctgagc ttctaccgtt ccctgctgaa gagctgtgta
    27481 aagctcattg aaagccagag gagttggatt agcccccagg tttttccaga gggacatgtg
    27541 atatttattc tccatagtcc ggatagtaag cccctttaca tcctccggca cacggatttc
    27601 cttattagct gtggtaacac ggaagcctaa tgacgaaagt cccatcatat agaagccagc
    27661 cttgtcatat tctgctgaca gcgcgtcgat aaattcctga tcagcaaata ccttttccat
    27721 ctgctcctct gtctggaaag caaacgggcc atcaaagaca atggcgctgt ttacaaaatt
    27781 agcctgagct gcgcttccgc aggtcatcat agtaatgctt ccctcctgta ctccctctat
    27841 ctgttctctg tcccctccca tctgggaatt tggataaata ttaacagtaa tttttccttc
    27901 cgagttctcc tccacatatt ccttaaaagc aagacagcct gcctgctggg aggtatcctc
    27961 tgccacggca tgtgttaaag taatggtata gttttcaccc gacgagttct ccgcgttttt
    28021 agagttatct gttcctcctg aacatcctgc cagatttact gctaatattc ccgccatcaa
    28081 tatagaaatc actgcttttt tcattgtaat tcctcccctt ctcctgtatt tcctatatcg
    28141 ctctgctgtt tttataatcc cagctgtttt ttgtttacaa tgttttccgg ccgctcccct
    28201 ctcagaaggc gaaccgctgt ctgggcagcc tgggtatgct gctcgtctga tgcctcggca
    28261 gagctgtagg ctacatgcgg cgttacaacc gcctgttcaa actgaaacag cctggcattc
    28321 ttatcagaaa tcggttctcc ctccataacg tccagaccaa ctgccgccac cttgcctgaa
    28381 tctaaagcat ccatcaaatc ctgcaaattg ataatactgc ctctggaggt attgacaatc
    28441 atcactccat ccttcatttt gccaattgtc tcccgacaga ttaagtgctt cgtctcctct
    28501 gtagctggca catgaagaga aatgatatct gcctggctgt aaatttcctc gtaggacact
    28561 ggttccactc catgctctct aaaaacctct gccggcagat agggatcgct ggccaaaact
    28621 ttcattccca gtccttttgc aaagccagcc agaattctgg ccgtccttcc aaaccccata
    28681 agccccagaa ctgtagatga aaatcggtgc atttcatagc cgtatccagg atcccactgg
    28741 ccctcatgaa gtcttctgtc atataaagtc agttttcggc gcagatccag aattaagccc
    28801 aaagcgtgcg aagccacatc ctccacacag taggtcggca ggttgcagac tgccactccc
    28861 cttcttccag ctgcctcgat gtccactaca tcataaccga tgccatagcg gatgacagcc
    28921 tgcagcttcg gcagctttga cagcagcacg tcgtcaatct tgaaatacac atctccgatc
    28981 acgtccgcat ccgaacagaa gtctacaact tcgtccatag ttttacattg agcgatcaca
    29041 cattcgtacc cggcttctgc aaggatctct ctttcctggt gataatctgc ttcaggaagt
    29101 gtgtgcgcat ccagcattac aaattttttc actgctatac ctcctcgtat tctctattct
    29161 tcttatacca aaagaagact gattggctct acaaacgtaa tgagcaaaag ggctgctaaa
    29221 aaaacgagaa taaacggcac tgctttctta gcaatctgaa tgactggtat ttttgtaaga
    29281 gaactggcca caaacagatt cactccaata ggaggagtta caaatccaac tgccagattt
    29341 actaccataa tgactccaaa atgaattggc gaaattccaa gctgcgttac aatcggcagg
    29401 aaaatcggcg tcagaatcag aatcgccgga gtagtgtcca taatcattcc tacaaataaa
    29461 aggaatacgt tgattactaa cagcacctct attttggagg taaagctggc tgtcatcaca
    29521 ctggctatca tttgaggagc ctgcatcatt gtaagcaccc ggccaaatac agtggcagtc
    29581 gatacaacta acagaacagg cgccgccgtc ttagccgctt cttttaacgc tcctggaata
    29641 tctgaaattt tgaaggtttt gtagatgaaa atactcacca caagcgcgta gataactgaa
    29701 atatctgcag cttctgtagg agttacaatt cctccataaa ttcctcccaa aatgataacc
    29761 ggagtcagaa gcgcccaaaa actatcgcgg aaggtgcgga aaaatccctg ttttctgata
    29821 gactcgtaat tcgccttcag cttctcctta tcttccccct taatccggca atagccatat
    29881 gcgtaaatca taaggaacaa gcctatcaaa attccaggaa gaatgcccgc aataaacagc
    29941 tttcccaccg attcgccgga tgacaaaccg tacataataa aagggatgct aggtggaata
    30001 atcactccca gtcctcctga cacagccacc atggcagtca caaattcacg ttcatatccc
    30061 agccgcacca gaagcggaat agacatggct cctacagctg ctactgtagc tggaccagaa
    30121 ccggaaatag ccccataaaa caaacaggta acgataactg ctatcggcag accggctgtc
    30181 ctgtttccta caaaatatgc aaaaaaatca aacagttttt tagaaatgcc tccttgggcc
    30241 atgataactc ctgacagaat aaacaacggc accgctaaga gagcgtaggt atcaagcgca
    30301 gttaccatat ttcggaaaat aaaatccgct gtcgccggaa ggctgggatt tgcccacgat
    30361 gcagtcaggc ttgtaagtcc tactgacaca ccaatgggaa ttccaagaaa aattgtcaca
    30421 aaaaatgccg ccagcacaat tcctatgttc attccttctt atcccccttt cctgccagaa
    30481 gcagcacata tttttgaatc atgcgcacga tagtgagcag aaagccgccc atcagcgaaa
    30541 tataaaccag atacataggc acacccatag ccggactttt ctgactggat gcaatcagca
    30601 tccccatagc cttgaatcct ggctgtatca tataaacgct gaatgctaaa aacgctatat
    30661 cctgcagcac tcccagtatg cgcttcgttc tgggaaatac agtttcaata atatctacct
    30721 taatatggat attctgtctc accccatagc tgattcccat aaatacaaac cagataaaaa
    30781 aatatctgga cagttcttct gcccatacca gagaactttt caggccatat ctcataacta
    30841 cctgaatccc cattaccacc actatcatgg ccagaagtat cagcataatt gtttcctcaa
    30901 aatgccgatc cagccatcta agcactttca taaaactctc ccttctcact tatctgaagt
    30961 cagatacact gattaatccg aaggccgttc agcgaatctc ttttcgccaa atcgatatgc
    31021 gttctcagct ctgtctcaat ctcactgtcc tttgtcacca aaagttctaa aagcctggaa
    31081 tgagacttta cataatctgc agaatgtgtc ttcggatcca aggtattaga attgaacttg
    31141 gccaaagcct gtatcgtagg ctcaatggta ttccagcacc gcagaagcgg cttgttatct
    31201 gacataataa gaagcgtttt gtgaaatcga tcgtttgcat tgaagcgttc ctctttcatc
    31261 acatcaggct gttcctgcga cagcttttgg aatacatcta ccgcctcata aagaggacca
    31321 aaatttacat agtccttttg aagaattgta cggactgcct ggcattccag cagcgcccgt
    31381 gtctcgtaca gatcgtggac aaactgcttc gtaatgccgc atacccgttt tcttccattt
    31441 gccagagttt caatcaagcc ttcgctttcc agcatctgca tggctgtgcg aaccgttcct
    31501 ctggacgttc catactcccc tgctaaagcc agctctgtca gcatgactcc atctggatat
    31561 tctcctaaaa taatcctgtc tctcaaattc tcaataacat ttgcaactgt tattgtcctg
    31621 gttacgctat cgatagctgc catctgcatc ccttctttca tatccgttta tagataatat
    31681 tataattctt acatttttca ttgtcaacat tagttaaata tttgtcttac tttttatata
    31741 taattgtcga caatttattt atatttctgt aacgcaaact tccgctccac gcaaaaagag
    31801 cctgctccag aatttccatt ctgaagcagg ctctcttctg ctctccaaag actacagttc
    31861 cggcttctca acctgaacaa tggcatcctt acgcatcgga atacggcagt tcttgttgct
    31921 gccgaactca acgattacag tgtcatctgt catatcaatg acaacaccat acattccgct
    31981 ggatgttaaa acgctgtcgc cgatagccac gctggctaaa agctcctgca ttttcttttt
    32041 ctctttcttc tgaggtctga tagcgataaa gtacataagt ccaatcagga atacaaagta
    32101 cactatccat cccattgcgt tcatgtgtta tttcctcctt catccagatt cggcgcctcg
    32161 ccgcgaaatc ttaatttttt tctccctccg ccatgcgggc cagcttctca gccttgtact
    32221 ctgcgtagcg gtgatgttcg attgcgtcgc gaatctcttc catcatttta ttataaaaat
    32281 acaaattatg caagacgcat aatctcatac cgagcatttc ttttgccttc atcaaatggc
    32341 ggatataagc tctgctgtaa gaacggcagg ccgggcactg gcatccttcc tcaatcggtc
    32401 tcggatccag ctcatacttg gcattaaaca tattcagctt tccatgattt gtgtatacat
    32461 ggccatggcg tccgtttctg gacggataga cgcagtcgaa gaaatccacg cctctgtcta
    32521 ccgcctccag gatattggcc ggtgttccca cacccatcag gtacgtaggc ttttcctccg
    32581 gcagatgggg aactacctcg tcgagaatcc ggtacatctc ctcgtgactc tctcctaccg
    32641 ccagaccgcc tactgcatag ccgtctaaat ccagcctgct gatctcctct gcatgggcga
    32701 ttctgatgtc ctcatagaca gctccctggt tgattccaaa gaggagctgc tctttgttga
    32761 ctgtatcagg caggctgttt aaccgctcca tctcagcctt acagcgcttc agccatctgg
    32821 tggtgcgctc tactgagttc tgaacgtact ccctgctggc cttgctgggc ggacactcat
    32881 caaaagccat agcgatggtg gaacccagat tggactgaat ctgcatgctc tcctccggcc
    32941 ccatgaaaat tttcctgccg tcgatatggg agttaaagta cactccctcc tccttgattt
    33001 ttctgagtcc tgacagggag aaaacctgaa agccgccgga gtcagtcaga attggccgat
    33061 cccagtgcat aaatttgtga agtcctccaa actgcttaat cagcttgtct cctgttctca
    33121 catggaggtg atacgtattg gaaagctcca cctgggttcc tatggtcttc aaatcatcgg
    33181 tggaaaccgc tcccttaatg gctgctacgg ttcccacatt cataaaaacg ggcgtctgga
    33241 tcgtgccgtg aactgtcttc atctcagccc gtttggcacg tccgtccttt gccagaatct
    33301 tatattccat tcttttcctt tctgcggctc atctcatacc acatagcgcc tgtcaggcag
    33361 acagaggaat aagttccgca tacaatacct accattaatg gaagggcaaa ctcacggatg
    33421 gaggaaactc ccataatgta gagtgccaga accataataa aggtagtcag agaggtgttg
    33481 atgcttcgtg tgaaggtctg agtaatactt aaatttacaa cctcctccag gctctgatca
    33541 cggcgtctct ccttcatatt ttctctgata cggtcaaaga taacaatagt agcgttgatc
    33601 gagtatccta caatcgtaag catgcaggca atgaatgtag aaccaacgga ccacttgaaa
    33661 gcagcatagc aggccaggac aactaataca tcatgaacta acgccagcac agagcttcct
    33721 gcaaaccgaa tgttcttaaa ccggagccag atgtagagca gcataccgat tgtggcaata
    33781 ataacggctg ccatggcatc tctcttcatc tcctggctga ctgctccgga aatactctcc
    33841 gccgcaattt ttccttcctc tacgccgaaa ttctcctgca tggccttttc aaaggcctga
    33901 cgctcctcta cattcagggt tctcgtctta atgataacct cgtttgtgcc tgttacacgc
    33961 tgagtctgaa cgtcagcgtc ctttgtaatc tcctctacta acggaactac ctcagactca
    34021 atgcgctcct gactcatctc ctcgttgaaa gttacgttag tagacgtacc tcccttaaac
    34081 tccatgctgt agtttaagat ctggcctgta gaggaacggt tcattcccat aaacacgaaa
    34141 ccggctgcca ctgctgcagc tgaaagtaca aagcagaact ttctgtactt taagaatggc
    34201 ttcggagctg tctccttctt aattccatag aacttcgcat tttcaattcc cagggaatac
    34261 agggcattta aagcaaatct tgtcacaaac agagctgtga acatagagag cacgataccg
    34321 atagccagag tggaagcaaa gcccttcact gtgccggatc ctctccagaa cagaactgcc
    34381 gctgcaatta aggtggtcac gtttccgtcc acaatggcgg aaagagcctt ctggaagccg
    34441 ttgtcaatgg cagttttcac agcctttccg gctccgatct cttccttaat acgggtgaag
    34501 ataatgacgt tggcgtccac cgccataccg atggacagga tgatacctgc cacgcccgga
    34561 agcgtcagag tcacctcaaa ggatactaag agaatcagaa tcagtcccac atagaggctt
    34621 aaagccagca ctgccgccag acctggaatc aggtaaacgg caatcataaa tacagccaca
    34681 atggcaaagc ccacagctcc tgcctttaag ctggtagtaa tggcctgctg gcccagcttg
    34741 gcgcccacca cgttggagcg cagctcctcc agctccaggg aaagggaacc gatccggatg
    34801 gtggcggcca gattctccgc ctcctcaaag tctgacattc cgtcaatggt gcactgtccg
    34861 cctgtgatgg cctctctgac tacaggagcg gataccacct cgttgtcgta cacaatgtaa
    34921 atcggttttc ccacattgtt ggtggtagcg tctgcaaagg ccttggttcc ctcctctgtg
    34981 aaggtcaggg aaaccacata ttcctttcca gtattgccgt ccaccattcc gccctgagcg
    35041 gaagccacct gatcgcctgt cagaatggta tttccctggg agtccataaa cgccagggaa
    35101 cccggctttc caagctctgt cagaatctca ttggcgtcag attctcctgg aatgtcgatg
    35161 ttaatgcggt tgtctccctc ctggtaaacc tccgcctccg tactgtagct ctccaccctc
    35221 tgctggagct tgtaaatcgt gtcgctcata tcctcggcag acgggttttc ctcttttgcc
    35281 tgatacgtaa tgctgactcc tccggccagg tccagtccca gcttaatgtc atccatatag
    35341 ctgtagccga aaaatccggc tatggcaatc aggaccagaa ggagagccag gcgtaccatg
    35401 gcttttcctt tactgctctt catgttcctt ctcctttgtc tcactttcat cggctaacgc
    35461 agcttttatc ataatggagc actcaatgcg ctttttctgc atctcgcatc caatatcata
    35521 cgcatctgta atggaaccgt ggaaattgta ggagttggcc gcgcagccgc cgctgcagta
    35581 gaatctggcg aagcagtccc ggcacttgtc cttggcatag acattgcaga gcttaaactc
    35641 attgcagatc tccggatggg taatgccctc ctccacattt cccagaagga acttgtcaat
    35701 tcccacaaac tgatggcagg ggtagaaatc gccccacgga gtaactgcca gatactcggt
    35761 tcctgaaccg cagccggaaa ggcgcttggc cacgcaggga ccctggttta aatccagcat
    35821 aaagtggaag aaggtaaagc cctttccttc cttatggcgt ttaatatact cctttgccag
    35881 cttgtcgtac tcctccataa tcttcggaag atcctcctcc cggatagaat agggctcctc
    35941 cggagcagcc acaaccggct cgatggacat cttctcaaag cccagatcgg caaagtgaag
    36001 cacgtcgtct gcgaaatcca ggttatttct ggtaaaggtt ccgcggacaa agtaatcctt
    36061 ctccccacgg gatttggcaa acttctggaa cttcggaaca atcaggtcat agcttccctt
    36121 gccgtttctg aacggacgca tcctgtcgtt gacttcccgg cgtccgtcca ggctcagaac
    36181 cacattgctc atctctttat tgcagaattc cataatctcg tcgtttaaca gaacgccgtt
    36241 ggtggtgagg gtaaagcgga atttcttgtg atgaggctcc tccagggaac ggccgtaggc
    36301 caccagctgc ttcaccacat cccagttcat cagcggctct ccgccgaaga aatccacctc
    36361 caggttaatc ctgtttccgg agttggccac caggaaatcc agggccttct ttcccacctc
    36421 gtaggtcata agggctcttc ttccgtggta ctcgccctcc tcggcgaagc agtactggca
    36481 ggccaggttg cagtcgtggg caatgtggag gcagagcgcc ttcaccaccg tttttctctt
    36541 cttaaaatca attacatagt ccttgtagac gtctgccgta aagagctgtt ccatatcgat
    36601 cagctcctga atatcggaaa aggcttcctc catatcctgt ctcggatatg ttccctctaa
    36661 ttttccgaat acgtattcct tcgcctcctc cggaaccgta accggctctg tcaggttatc
    36721 tatcttctca gagagaagcc cgatcatatc ataaagcatc ggatccacca catggaccga
    36781 tccgctgttt acatccatta caatgtaata atcattatta atatactgat gaatcacaga
    36841 ttttctcctt atctaatgtt tgcgcagccc tattccacac gtccccctta tacaatggta
    36901 aagcccctgc aattaaataa ttgcaggggc agcccatctg cctataactg ctggaacctc
    36961 agctcaggga acggtatccg ttctgcctga aaaactagcg gtccttgttc tcgcagctct
    37021 ggtttcctac tgtacaggat gtcttgcatg cggactggca ggatgtctgg cactcgccgc
    37081 atccgccctt tctcattgta ttctttaatg tgtttgtgtt taaagtctta acgtgcttca
    37141 ttctgtatgc cctcctatca tggatttcga tataatttcg tacaaattat agcatatgtt
    37201 tgactccagt gcaagcagaa cacagctctg tccgcatatt caggaaatcc ccggaatata
    37261 ttgaaagcag aatcaggcaa tcagggggaa ttttatgaaa ccatcgaaac tgcaggctgt
    37321 cgtgcggggg acgctgttct cctacgtcct gacggctctg ctgctgacag ccctggcctt
    37381 tcttctctac cgcttccggc tgggagaaag ccaggtcagt ctgggaatca atctggtcta
    37441 cgtcgtctcc tgcctggccg gaggttttct ggccggaaaa gcagccaggc agagacgttt
    37501 tctctgggga ctttttacag gaatccttta ctttctgatt ctctttttcg catcctttgc
    37561 agtcagcagg gagctggggg caggaagcag ggaactgctc accgtctttc tcatgtgcgc
    37621 cggaagcggc acgatcgggg ggatggtgag ctaaaggcag acagcagata tggaaaaagg
    37681 gacgcttcgc tctccttttc agaaagcaaa acgccccttc ttctgctgtg cttctatgct
    37741 gcagcttcct gtttcatgca gtttttcgta tctgtcctat tctgcgttct ttttcttctc
    37801 ttctctgcgc tcttcctctt ccttcatcct ggcagatacc gcctgcaccg gattcaggat
    37861 atagagatgg atccggtcga tccggttctt ctccacccgg tctaccacga gacggacatt
    37921 gtcgaatacc acgtcctccc cttcctccgg aagatggtct aacaggccga tcacaagacc
    37981 gcctaccgag tcgtaatcct ccgactccag cttcagctcc agcctgtcgt ttaagtcgtc
    38041 aagcttcata gagccttcca ccacatactc gttggcagca atctccacca gctcgttttc
    38101 ctcgtcttcg tcgtactcgt cgcggatatc tcccacgatc tcctccagca tgtcttccag
    38161 agtgatgagg cccgccgtcg cgccgtactc gtccagaacg ataataatat ttacattggc
    38221 ctttttcatc tccaccatca actcggaaac cttcttgaac tcataggtgt agtaaggcgc
    38281 tctcagataa tctctcacgg aaaactgctc ccgctctccg gccagcagaa tatcctttac
    38341 attcaaaatg ccgatgacat tgtccgtcgt ctcctcgtac accggaaatc tggtgtactt
    38401 ctcctggcgg aatatctcaa taacctcctc gtaggaagcg ttcacgtcca caaaggccat
    38461 gtcgattctg ggaaccatca cgtccttggc cacggaatct ccgaagtcga acacattgtt
    38521 aatcatcttc ttctcttccg tctcaatgac gccctcctcg tggctcacct ccacgatggt
    38581 gcgcagctcg tcctctgtga tggattccgc cttcttgttg ggatcgactc ccaccagctt
    38641 taagacaaga agggacagct tgttgatcac gaaaataaac ggggtgaaca acaccatcaa
    38701 aacaaaaatc acgcctgcgc agcgcagcga catcttctca gaggaaaggg tcgccgaggt
    38761 cttcggggta atctctccga aaatcaaaat caggaaggta atcacgcctg tggccgctcc
    38821 taccatctcg tttccaaaca gcttggacga taaaagggta gttaaggagg aagcatacat
    38881 atttacaatg ttgtttccaa tcagaatcgc gctgagcatc ttgcctggat ttcccgtcac
    38941 cttcagaacc atggcagccc gcgaatcgcc ggcgtccgcc aatgtccgta tgcggatttt
    39001 gttgactgtg gtcagggccg tctctgacga tgagaaaaat gcagaaaggg caactaaaac
    39061 aagaataatt aacaattgta tggcgtcact cgactccaaa aaaatcaacc tctactttct
    39121 tttttgccag ctccggctca caccggactg aactattttt aaaggtaatt ttacacgaat
    39181 ctgccttttc tgtcaatcgt gttccccggc agaacttatg attttcatat cagctcagcc
    39241 ctgcgtcttc ctgcccgctt cattttcaaa caggcttttc accgtcagga cagcggctcc
    39301 ggccataata aagagatccc ccaggttaaa caccactttc tttaaaaatc cggcctgaat
    39361 gctgaagtag tctaccacat agccccgtct cagcctgtcg tagagattgc tgagtcctcc
    39421 tgcaagcacc agggcatatc ccgccttttc cgcccggtat cccttctgag ctgagagaaa
    39481 gcacaaaatt ccccctgcca tgctggtcag gcacagaggc agctggcgca ccagactggg
    39541 tctgtgcttt aaaacttcaa agcagaatcc cctgttatga tttctgtaaa gtttaatcct
    39601 tccccctgtg tgatccatac tcctggggaa tcgttccgga ttctgcccct ccaccagctg
    39661 cttcaggcac tggtcaagcc cgaacagcgc agcggccgct cccaataaat acatagccgt
    39721 ctcctttctt tctgacaatc ccgtctgttc tgcttcctat cctatcacgg ttttctgctc
    39781 cggtaaagcc gggaaatccc ttcttttccc gcatgtttcg gcatctctct catatagttt
    39841 agaaacaaat atttccagag gtaaaaccat gccctgctcg catcccgccg cttcttcgga
    39901 atacgctgat tttattatac gctattttgc ctttccccag tcccttttat ccaccattga
    39961 agaaggatgt ctttctttta tcaacagcca gtttgcagtt gtatacaggc ctgtggagga
    40021 agcgcttccc atcacgctca acagttactc ctactcctcc atccccaatc tctacacgct
    40081 gttagacgcc tcaagtatgg aaagctccgg cattctgacc tccttcagcc agcctttcct
    40141 gaacacgcag ggagaaaata cgattatcgg tattattgac acgggaatcg actaccgaaa
    40201 tcctgttttt ctgggagagg atcgctccac caggatcctg ggaatctggg atcagacgat
    40261 tgagctgaac gaaagcggcg tttctgggga aagggccgga cagcttccgg aagatatttt
    40321 ctacggaact gcctacacga aggaggacat cgaccgggcg ctggcctccg attcgcccct
    40381 ggatatcgtt ccatctaccg atgaaaacgg acatggaacc ttcctggccg ggatcgccgc
    40441 aggcagacag gagctgtccg gaggggaagc ctttacaggc gccgccccca gggcctttat
    40501 cgctgcagtc aaattaaagc cggccaaaca gtatctgcgg gattactatg tgctccctga
    40561 ttctgccgag gcctatcagg aaaacgatat catgatggga atgaaatatc tgctgtccct
    40621 tgccaggaca aaaaggcttc ccctgacgat tctgctggcc ctgggaacaa acctgggaag
    40681 ccacgaggga acctcccctc tggcccagta tctggatact atcagcaatt ttcccggcat
    40741 tatcacagtg acggccgctg gcaatgaaac tggatacagc caccatttct tcggaaccat
    40801 cgggacggac gcggaatttg aggacgcgga gcttcgtgtg gccgagggcg agaccggctt
    40861 caccctggag ctttggtctc aggagccaga actgttctcc atcggctttc tctcccctac
    40921 aggggagcag atcggccgta ttcctaatca taccctcacc gagcagcgca ttacctttgt
    40981 cctggaaaat acagtgattt atctgaacta tcaggtggcg gaggccggca ccggaagcca
    41041 gctcattgtc atgcgctttg taaagcccac cccgggtatc tggagaatcc gggtctacaa
    41101 ctccctctat ctgcggggcg agtaccacct gtggctgccg tctaaaggct ttatctctga
    41161 cgacaccttt tttctgcgcc cttcccccga cacggtggtg acggagcctg gaaatgcctc
    41221 ccagactatc accgccggag ccttcaacca ccgaaacggc ggcatttata tccactccag
    41281 ccggggctac acccgcctgg gccgcgtcaa gccggatctg gctgctccag gcgtcaatgt
    41341 ggacggcccc ggtatccagg gatccgccgg ttttcccatg cgcgccatga caggaacctc
    41401 cgcggcggcg gcccatgtgg caggcgcggc agccaatctc ctgtcctggt ccttccgtga
    41461 gggcagcatt tcttatatga atacctctgt ggccaaaacc tatctgatac ggggcgcaga
    41521 ccggaatcct gtcttcgcct atcccaaccg ggaatgggga tacggaaccc tcaatcttta
    41581 cggcgcattc ctgcggctga gggagtgaaa gccctgctca gaagatgaga aattttcctc
    41641 tggcttcctc cttgactgtc tggaagggat atgaaataat tgaatcaaat tccagttgtt
    41701 ccattcactt tattttcctg ctcaggaggt gtgcttatgg caaagaatag aaagctgctg
    41761 tttctgacaa tcgccttatt atttcagatt ttctttctgt accaggcggt ttttaactat
    41821 cacgtataca cgctggatcc tgcgttccgt tcctttgctg aggattttca gtccgatgcc
    41881 ttttcagacg ggtacaccgg ggctcttttt atcgcggaac tgcttttcca gtgcgccctc
    41941 ttcttatcgt ttgtctatgc ggctgtatcg tctccagcgc tttcctgggg aaaactggct
    42001 ttcggcgcag cggcggcttt cctcctgtac cagggcctta tgtttttgtt ccgccagttc
    42061 tcctgccact gccgcctgta tatgacgctg gcagacacag agatcctgtc tctgtacctg
    42121 cttcttccgg ttctgcagcc tgccttgttc caaaagcaga aaatggccct gtagaaaaag
    42181 tttcctatag cgtcagtaca ccgacgctaa cataaaagca gaacagcttc tgccaaaaac
    42241 ctgcaaaagc tgctctgctg ctgttttttt ctattctttc tgtatttttc tgctctttct
    42301 atttcctcta gcccctcatc tcaatcatgg ggccgccgct tttctccaga taagctctgg
    42361 tgatcaccac ggatccaata ttgggatcct tgggaatctc atacataata tcctgcataa
    42421 agttctcgat aatcgcccgc agggctctgg cgcccgtctc ttttttcagg gcctcttccg
    42481 caatccactc cagggcgtcg tcctcgaaca ccagcttgac ctcatccatg gccagaagct
    42541 tctcatactg gcgcagaatg gcgttcttcg gctctgtgag aatgcggatc atcagctcct
    42601 ttgtcagggc ctgaagcgtt accataatgg ggagacgtcc cagaaactcc ggaatcatgc
    42661 cgaattttct cagatcctct gtagccgtat agctgagaag ctttggatcc tcatcgtatt
    42721 tccctttcag ctccgacgca aagcccatgg agctggactg gttcagcctc tccttaataa
    42781 tattctccag atccggaaag gctccgccgc agataaagag aatgttgttg gtatccaccg
    42841 tagtcatagg cgtcaatgcg ttcttctggt tcgatcccac cggcacctcc acctggcttc
    42901 cctccagaag ctttaacagc tcctgctgca ccgattctcc gctgacgtcg cggctggtcg
    42961 tattcttctt cttggcaatc ttgtcgatct cgtcgataaa aataatgccc ttctccgctc
    43021 tctccacatc gttgtcagcc gccgccagaa gcttggaaat cacgctctca atgtcgtctc
    43081 caatatagcc ggcctctgtc agagtcgtgg cgtctgcaat ggctaacggc acgtctaaaa
    43141 gccttgccag cgtctttacc agatacgtct ttccgcttcc tgttggtcca atcatcagga
    43201 tattggactt ttcaatctga acgtcgtcct ccgccccttc ctgtccagag gtctggcaga
    43261 acgctctctt ataatggttg tatacagcca cggcgatgac ctttttcgcc tgctcctggc
    43321 cgatcacgta ctgatccagc tttgatttga tcacgtgggg cgccggaatg tccttaatgg
    43381 aaaattcctt tttcgcctcc ttatcctggc ttttcttttt caccttattt ttcttcggaa
    43441 tctctgtatt caggttctga agattggaaa agtcgctgag attcatattc atgtagggca
    43501 tgttctgaag ctggctcaga tccaggccgc tctgggtcac tgtgtcgaag gccttctgca
    43561 tacagtcatg gcagaaattc atgcctcccg gcatagtaat catagggcct gccttgctct
    43621 ccggcctgcg gcacacatag cagatcttct cgtactcgtc gtccttatga tctgcctccc
    43681 tgtcagacgt tcctgcctcg tgcttctcct tttcggcatc cagaaccgcc gtctcctcag
    43741 acgcctcatt tcctctatct ctctcttcgt ttctgtcttt ctctctgtcg tccaaatcgc
    43801 tctccctttc ccagctggtt cagccatttc tccccagctg tctcctgcaa aagctgcatg
    43861 agagtatcat actatatttt catcgtctta gcaatcctgc ggccgctccg gattcaggaa
    43921 attatatcca ttcagccgca cgttttctgt cttcctgcag cagacaagaa gaaaagaaat
    43981 cttcccgcag cttccaggtg aagcggggaa aatttctttt cttttttcta tctgctatct
    44041 attcagtatc tgttatctat tcagctgctt atttctcctg atcctgctgc aggttcttct
    44101 ctgcgtcctt tctgtagccc agagtcacct gaacctctct ctcggcgtaa gcgccgttgt
    44161 ccaaggactg tacggtcaga gtcacaatct cgcccccctt atagtaggtc agcattttct
    44221 gcagatcctc tgccgttctc accgtctctc cgtttacctt ggtgataatg tctctctccc
    44281 gcaggccgga tccgtctgca gccaggcctt ccacaatctt gtagacgtag attccctccg
    44341 gcattccgta ggccttggcc atctggctgt tgatatcctg aatctggatt cccaggtatc
    44401 cctgctcatc ctctgccacc gctaccttgg tggtcttggc catcaggtcg tcgataatgt
    44461 cctttgcata ggagatcgga atggcgtagc ctacgccctc tacctctgtg ctggccatct
    44521 tggcctcgtt aatgccaatg agctttccat tcatgtccag aagcgctccg ccgctgtttc
    44581 cagggttgat ggccgcgtct acctggatca gattttttgt cacgccttca atatccactt
    44641 ccttattgag agcgctgatg tagcccactg tgacggactg tccttcgccc agggcgtttc
    44701 caatggcaat cacgccgttt ccaagcttta agctgtcgga gtctcccata tcagccacct
    44761 taatctggga cagggtctcc gccggaatgt cgcttaactg cacggcaatc accgccagat
    44821 ccgcgtccac atctgttccc tttaatgcag ccgctgcgga gcttccgtcg ataaaggtta
    44881 cattcatctc ctctgcattt gcaattacat ggctgtttgt cacaaccaga agctctgtgt
    44941 cgctctttcc tacaatgatt cccgaacctg cgctggacgc ctcgtactgc tgggttccaa
    45001 agaaccagtc ctctgtcgtg taaagcgtct tattgttaat cgctaccact gacggcatgg
    45061 ccttttctac aatggcagac acgtcgttgc ctgtgctggc ctgaatcacc gctccgctgg
    45121 atgcctgggc ctgagtttcc ggctgcggcg cctctgtgga ggcctgggct gatatctctg
    45181 tcttttctgt ctggcttccg cctgtcaggt aattgattcc cgccatggtt ccgcctgcca
    45241 cgcagccaaa cagcagtccg gcggccgcga tcccggccgc tttcttagcc agccggcttc
    45301 ctttctttcc gcttctgtga gagtcgccgc cgttttcctg gttcccgctg ttctccgcct
    45361 tctgccagct gctctcattt ctgccttcct ggctctggct gcttccatac tgatacgttc
    45421 cgcagcctgt attttcttct gacggtcttc tgatctggcc gtacatgcgg cggcctgcgc
    45481 tccgatcctc tgaacgccct gtgtggacgc cgtccacgta agacccctcc gtgatatcca
    45541 catcattttc tccatttaac ggctcgtgat ttttctccca gtctttctca ttatacataa
    45601 cagctgctcc ttcctctgtt cctatctatc gttcataata ccttatgatg tcttcttttt
    45661 gtttacagcc atagtctacc aatgatttgt gatggaaatg tgaaaatttt ataatgaaat
    45721 tgtgttttct gccggtttcc tatctgctat actgtgtata gcgtcagcgg gcagggaaca
    45781 gcacgccttt gtgcgctggc atcagcgtcc acggacgccg cagagaggag agaatatgac
    45841 catgaataca aatgcagttg tacatattaa aaaaggaggc gccagagctt taaaggcagg
    45901 aggcgcatgg atttatgaca atgaaatcga acggattgaa ggcagctttg aaaacggcga
    45961 cctggcgaca gtctgcgatt tcgacggcta ctgcctgggt tacggcttca tcaacacccg
    46021 ttccaaaatc acggtgcgca tgatgtcccg gaaaaaggac tcggtgattg acgacgcgtt
    46081 cctggaaatg agaatccgca acgcctggga atacagaaag gcagtgggcg acatttccag
    46141 ctgccgcgtc atcttcggag aagctgactt cctgcccggc attgtcattg acaaattttc
    46201 ggacgtcctg gtggtggaat ccctggccct tggcattgac cggatgaagc ttactattgt
    46261 ggatatttta aagcgggtgc tggctgagga cggaatcatc atccgcggcg tctacgagcg
    46321 cagcgacgcc aaggtccgcc tgcaggaggg catggagaga atcaagggat ttatcggaga
    46381 accgtttgac acaaaggtgg aaatcgtgga aaacggcgtc cgctacctgg tagacgtcaa
    46441 ggacggacag aaaaccggct tcttcctgga tcagaaatac aaccgcctgg ccatccagaa
    46501 gctatgcccc ggaaaacgcg ttctggactg tttcacccat accggttcct tcgccctcaa
    46561 cgcaggaatc gcaggggcga aagaagtgtt gggcgtggac gcctcggagc tgggcgtcag
    46621 ccaggcccgt gaaaacgccg cgttaaacgg cctctccgac cgcgtttcct tcgtatgcgc
    46681 cgacgtgttc gagctgcttc ctgagctgga gcagaagggc gagaaattcg acgtagtcat
    46741 cctggatcct cccgccttca caaaatccag aaactctgtg aaaaacgcag tgaagggcta
    46801 ccgggaaatc aacctgagag gaatgaagct ggtcaaggac ggcggctatc tggccacctg
    46861 ctcctgctcc cactttatga cgccggagct gttcacaaaa accatccgcg aggcggctgg
    46921 aaacgtccac aagcggctca ggcaggtgga gtacagaacc caggcagcag accatcccat
    46981 tttatgggct gcagacgaat cctactactt aaagttcatc atcttccagg tcgttgatga
    47041 gaagtaattt ttcagaatgg cagaaatcct tgatttatac ggtttacagt gcatttgtta
    47101 aaaatgtgaa actatcgtaa cttatcggaa aatggtgtaa ttttatagcc agatggtgta
    47161 gtaaatggtg taaatcaaag ggtatgcaga tgtaaaaagg gatatcccaa atcactctct
    47221 tggaatatcc cttatatatt atttttcctt atctccggtc tgataccact tcattcaact
    47281 tgatacttaa ttatcctcta ctctgaaact tgacaatata gcaatgacct ctgtctgttc
    47341 cgcttctgtg aactgtccgt ctggtgcttg tgctgtgaat gaaacatagc cactatacca
    47401 gaatgtattt tgaacacgca aaggaagatc tgttgtttct tctgtcccgg ttctgttttc
    47461 cggcaaaaca gcaaaag
//
LOCUS       DBMDUW010000015        47364 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_693_length_47364_cov_3.406745, whole genome shotgun sequence.
ACCESSION   DBMDUW010000015 DBMDUW010000000
VERSION     DBMDUW010000015.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 47364)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 47364)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47364
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_693_length_47364_cov_3.406745"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            118..909
                     /locus_tag="ACZPCR_04710"
     CDS             118..909
                     /locus_tag="ACZPCR_04710"
                     /inference="COORDINATES: protein motif:HMM:NF012742.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HIR1230207.1"
                     /translation="MEDPYYLSVRIAIERRAAELGCRLVSISEKDEFRVSGIDGVICL
                     GTFGTEELKRIDELERPTIFVDSNPNYDKYDSIVFDLRRETRRILDYLWEKGHRRIGF
                     IGGNDMEGPGTFAETDKRTLEYRAFMEEKKEEGVSYERIGAFTSRMGFRLMNELMALP
                     EPPTAVFVANDSLAVGCLNAISRAGKRCPEDFSIVGFNDIPTAKYMVPPLTTMRLYMD
                     FMGERAVDLLSDRILTKRELPVQVTLPAKLMIRESVKDLTADSSL"
     gene            1020..2132
                     /locus_tag="ACZPCR_04715"
     CDS             1020..2132
                     /locus_tag="ACZPCR_04715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013271512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1230208.1"
                     /translation="MSTVKLEHICKKYPNGFEAVKDFNLEIGDKEFIIFVGPSGCGKS
                     TTLRMVAGLEDISGGDLYIDGKRMNDVEPKDRDIAMVFQNYALYPHMTVYENMAFGLK
                     IRKVPKDEIDKKVHEAAKILDLEHLLDRKPKALSGGQRQRVAMGRAIVRNPKVFLMDE
                     PLSNLDAKLRGQMRIEISKLHQKLGTTIIYVTHDQTEAMTLGTRIVVMKDGVVQQVDT
                     PENLYDKPGNKFVAGFIGAPQMNMVDAEVKEDAEGVHLVFCGQSIKMDEKRAAILKEK
                     GYIGKKVTLGIRPEDLHDESDSERGNKDACLNATIRVYEMLGAETFLYFDMDTATWTA
                     RVNPSVRVKPGEAIKLYMDTEKIHAFDTETENAIFN"
     gene            2240..3397
                     /locus_tag="ACZPCR_04720"
     CDS             2240..3397
                     /locus_tag="ACZPCR_04720"
                     /inference="COORDINATES: protein motif:HMM:NF037653.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HIR1230209.1"
                     /translation="MVSKRALKHVLGEIRDASGLSLALFGGKGELLALSEGEGQLFEE
                     LEKEGLVSDRLKEYVRSLAEGGEKTWQRGGVCFLRTGNERGEGFVLAGTGKEDVLPLL
                     RLSAVALSGLFRRQEKRQDRDVFFRRLILGQLLPGEVSEQARLLRLDGRARRAVFLIK
                     VREDGCDTVLDILYPLYAGPAGGVLFQAEPGSFVYVRTLGEKEDTAKLEEIGKNMIDV
                     INTEGMEDAYLSFGMPAEELSFLNRSYEEAWIAMKAGRIFFREKHVISYDRLGIGRLI
                     YSLPMPLCRQFLGEVFAQADPGAFDEEALTTIRQFFEDSLNVAETARHLYIHRNTLVY
                     RLDKIQKGLGLNIRNFDDAMMLRLGLMVYEYVREKEQEEEKERKTDGRTDV"
     gene            3378..4076
                     /locus_tag="ACZPCR_04725"
     CDS             3378..4076
                     /locus_tag="ACZPCR_04725"
                     /inference="COORDINATES: protein motif:HMM:NF016726.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HIR1230210.1"
                     /translation="MVERMFNTDNHFWQTVGKAGDLIALTFLTLLCSLPLITAGAAFC
                     AMNYVCFKMLEHDNEGTIRNFFHSFRQNLFQGAALSLIMGAAGFLLWYDGWFLTRYFD
                     GQEGGAMLYAGWAVYIYLIFFYLILVLYVFPLQARFYNPLAVTFKNAVIAGFKNLPKT
                     LMMLAGDGAMAVLTVLCFKTFPQIAFLPLLTALPLCVWYHSWVLRDLLGLVPGKLDLP
                     VSDDKEERKEERYE"
     gene            4069..5862
                     /locus_tag="ACZPCR_04730"
     CDS             4069..5862
                     /locus_tag="ACZPCR_04730"
                     /inference="COORDINATES: protein motif:HMM:NF014647.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HIR1230211.1"
                     /translation="MSDFAGEQYKKARKAGIKAFREAGGKGRYPYLTSLDEILLHTKT
                     AGTEDLGVCEIPLSRVTGTKTASRSESFAWNFMPLLREKTEFSGKWERLYEAQMEEGI
                     REPVKVYEYMHHFYVREGNKRVSVMKYVGAVKITADVTRIFPKRDGKKAYEAFYQYAA
                     FNRATGLFELLFSEPDAYQKLAARFEETLAERWKEDKIKELRAAFGRFCSCYEKKARA
                     DSLTEESDAFFVYLEVFGYQGLLTDSDRQIRERMERAWEEMKLAGQKKKVALIEEHRE
                     AEEGKNSLFGFLHGGEKRPLRIAFINDKDSRTSAWAYGHRLGWQALKEKYGSQVKISV
                     YNHCDTPEAVRDALAKAVLQKNDIIFTTAGQMRAQALETAVNHPEIKFLNCSVNASYR
                     SIRSYYARMYEAKFILGMTAAALCEDGRIAYIADYPVYGAVANINAFAIGAQMVRPGV
                     KIYLKWSNLKKGDWKAEIKKSGFTMVSGPDLKLPSEESRLFGLFRYSQKKGDYENLAM
                     PFIDWGRYYCLLTESVMDGNFDSREFTKTGQAVNYFLGMSAQVVSVIFSSRVPYSVRK
                     MADVFEEAMIQGRFSPFDGEIRTKKGWLKGG"
     gene            5891..6025
                     /locus_tag="ACZPCR_04735"
     CDS             5891..6025
                     /locus_tag="ACZPCR_04735"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230212.1"
                     /translation="MKMDWLNDNVIGKIPGIDAFKEDARELLSALGVEAARTEEGGTP
                     "
     gene            6022..6690
                     /locus_tag="ACZPCR_04740"
     CDS             6022..6690
                     /locus_tag="ACZPCR_04740"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007155854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HIR1230213.1"
                     /translation="MKILIVADEESKALYDYYDSSRLKDIDLILSCGDLRASYLEFLV
                     TMGRAPVLYVMGNHDDRYKANPPEGCVCVEERVYNYKGLRIAGLGGCMRYKPDGIYLY
                     TEEEQRRRVQKLKRQLQRYHGADIFLTHAPAKGLGDGSDFPHQGFECFHEILDEFHPK
                     YLIHGHQHLNYGSGARRLEKGPTAIINGYGSYTLEIGPEEYPSEYENTGSLIFDLYNK
                     LRHR"
     gene            6772..8052
                     /locus_tag="ACZPCR_04745"
     CDS             6772..8052
                     /locus_tag="ACZPCR_04745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007717730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
                     /protein_id="HIR1230214.1"
                     /translation="MSKKRSIETTCIQGGWHPENGEARVLPIYQSTTFKYSTSEQMGR
                     LFDLEENGYFYTRLANPTNDAVAEKICEMEGGAAAMLTSSGQAANFYSVFNICSAGDH
                     FICAATVYGGTSNLFTVTMKKMGIEVTLVDPESTDEELDAAFRPNTKCVFGESIANPA
                     LVVLDIEKFARAAHRHGVPLIVDNTFATPINCRPFEWGADIVTHSTSKYMDGHAMSVG
                     GCIVDSGNFDWEAHKDKFPCLTEPDASYHGVVYTEKFGKGAYITKATAQVMRDLGSIQ
                     APMNAFLLNVGLETLHLRVPRHCENALKAAKYLKSREDVAWVNYPGLEGDRYYELAQK
                     YMPNGTCGVISFGLKGGREAAGVFMDKLKLAAIVTHVADARTCVLHPASHTHRQLTDE
                     QLAEAGVDPSMIRLSVGIENADDIIEDIRQALED"
     gene            8079..9629
                     /gene="cls"
                     /locus_tag="ACZPCR_04750"
     CDS             8079..9629
                     /gene="cls"
                     /locus_tag="ACZPCR_04750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HIR1230215.1"
                     /translation="MKKRKKLLRLVFGRTTFVVLFLLIQVGILLMGFAWLEEYMLYFY
                     GASVILSAVTLIYIISADESTSIKLSWVVPILVFPVFGTLFYLFVRLQIGTKLIGHRL
                     KMTSAETAPYLKQDTETAERFNEMSSSQGNLVRYMNRFAGCPVYQNTAAQYFPLGDDM
                     FVEMKRRLKAAKHFIFMEYFIVERGEMWNSILEILEEKVREGVEVRVMYDGMCCLMLL
                     PYSYPKTLREKGIKCKMFSPIRPALSTHQNNRDHRKICVIDGHTAFTGGVNLADEYIN
                     RKVRFGHWKDTAVMVEGDAAVGFTMMFLQMWGVTEQEKERYESYLKPADYRLPKDADA
                     SGFVIPYGDSPLDKENVGEQVYLDILGHAKKYVHIMTPYLILDDQMINALQYSAKRGV
                     ETIIIMPHIPDKMSAYLLARSYYEELLTAGVRIFEYTPGFVHGKVFTCDDEKAVVGTI
                     NLDFRSLYLHFECAAYFYKHPVVAQVEDDYQKTLEKCQEITIADCRNFPFFKRFMGKA
                     LRLFAPLM"
     gene            9820..10674
                     /locus_tag="ACZPCR_04755"
     CDS             9820..10674
                     /locus_tag="ACZPCR_04755"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006779833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HIR1230216.1"
                     /translation="MTEGALVLEGGSLRCLFTAGVLDVLTEENIQLSYVNGVSAGTMA
                     GMNYISGQKGRMLEISETYLHDKRYMGMRSLIKNRLVFNFDFIFGELSDELIPFDYEA
                     FYSSPQKFEAAATRCRTGKTEFFEKSQCSDMMKAVQASCSMPLLSKMVTVDHKKYLDG
                     GISLPIAYQRAMDLGYKKIVLVLTRNHGYRKKPLSSLAVRAYNRYFEPLPQLKAALFE
                     VPDRYNWMQEEIDRLEQEGRIFVIRPERPVRVSRLERDLKKLQALHQEGRETAVKLLP
                     ALRSYLEI"
     gene            10696..11688
                     /locus_tag="ACZPCR_04760"
     CDS             10696..11688
                     /locus_tag="ACZPCR_04760"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070573 - metallodipeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HIR1230217.1"
                     /translation="MKYIDMHCDTIPRLCHPKAGERGETLRKNSGHLDLERMKQGNAL
                     AQCFAVFTDLKAYPDPYVRAREILARFKKEMAENGGMIAQAFTAEDILRNDREGKMSA
                     ILTIEEGAVCQGSLERLREFYEEGVRMMTLTWNYPNDLAWPNRLDPQTGHMTPETERG
                     LTEKGAAFIEEMERLGMIIDVSHLGDAGFWDIAKRARKPFIASHSNSRSEAGHVRNLT
                     DEMIRALADRGGVMGINFCGVFLNSRNGNSPDGGDSRVSDMVRHMKHIRQTGGIECIG
                     LGSDFDGISGDLEVDSPAALYRIADEMSRQGFTGSEIDAVFYKNVLRVFTEILH"
     gene            11757..13418
                     /locus_tag="ACZPCR_04765"
     CDS             11757..13418
                     /locus_tag="ACZPCR_04765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HIR1230218.1"
                     /translation="MSISDLGMLFQFAGGLGMFLYGMNIMADGLQRSAGSRMQHMLGV
                     LTNNRLMGVLAGAAVTAIIQSSSATTVMVVGFVNAGIINLFQATGVIMGANIGTTITS
                     WIVSMSEWGEVLKPEFFAPFLFFIGAFLVLFTKSNKKKEGGEIMIGFALLFIGLSFMS
                     SSIEPYRDAPIFAQAFQTLGKNPILGVLTGLVVTAIIQSSSASVGILQTLALNGMVNW
                     QSAVFITLGQNIGTCVTALLSAVGASRTAKRAAVIHLLFNIFGTILFGTVMFVVFMLN
                     PAFAASTADSVGISIFHTVFNVSNTILLFPFAGILVKTACALVRDSKEEEKTGDVEGD
                     ILRHLDDRILESPSFAIETVEKEVINMGRVAAANLKIATAALTDRNESFCQEVFDNEK
                     KLNHLDTELTDYLVKINNLSLNDSQHLIVKNLFYTIGDVERIGDHAENLAELAQINIK
                     NNREFSESGLNDLKKISEAAIKSVESAMECREDRELSKVRQTARYEEEVDSLEEELKE
                     LHMERLSNHECNTKSGVIFLDAVSNYERIADHARNIAGYVKEEIE"
     gene            13421..14107
                     /locus_tag="ACZPCR_04770"
     CDS             13421..14107
                     /locus_tag="ACZPCR_04770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIR1230219.1"
                     /translation="MKHLIYVTEDDENIRNLICVALESFGYTTCAFETAEEALEAVRG
                     VEGSLPSLFVFDWMLPGMDGMAAVAKLKASPDTRKIPVMMLTAKDSELDVVAGLDGGA
                     DDYMTKPFGILEFSARIRNLLKRFGEEKEEDKSLAVGDISIDLEKREVKNKGEAVELT
                     LKEYELLCYLMENTNRVVTREELLDRIWGYDYDGETRTLDMHIKTLRQKLKESGHSIK
                     TIRGVGYRIS"
     gene            14137..15564
                     /locus_tag="ACZPCR_04775"
     CDS             14137..15564
                     /locus_tag="ACZPCR_04775"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007858223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1230220.1"
                     /translation="MKTAIFRKFIQLLLLALLLNTAILYIVTGSVILNNSRNDMVFIL
                     DTIDSAFHYEGDLEAQAERISQSANLNESRLTIIDPNGVVRVDTGVKDASELDNHMQR
                     EEFQEAVKTGEGDDRRRSKTLGKEMLYVAIQSSYSDCILRLAVPYTGMQDYIKMLFPA
                     VLLSFSVALIGSALEADRFSQSITKPLLEISKEMIKVNGDYTDFHFERCGYEEINIIA
                     DTTTRMSKNVRDYLNRLEQEKQIRQEFFSNASHELKTPITSIRGYVELLDTPMADNPQ
                     MRGDFLSRIKKEAVRMTSLIDDILMISRLETGGIQTELRELSAGELAREAVSSVEGMA
                     RERRIEIETDVEEFYICADGRQMEELFTNLLSNAVKYNLDGGKIWLSLKRKGTDMELQ
                     VRDNGVGIPKESVGRIFERFYRVDKGRSRKQGGTGLGLSIVKHVVNFYHGTVSVSSSQ
                     EEGDRGSIFTVRLPIAREAKQDSRV"
     gene            complement(15586..16143)
                     /locus_tag="ACZPCR_04780"
     CDS             complement(15586..16143)
                     /locus_tag="ACZPCR_04780"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230221.1"
                     /translation="MKPKVKQVLEGPLARAQLLIFGTAFYFEVIAAVCIIIGLIITFL
                     GVPRQILLLADTGAFITFLTFMFNIVIGIELLKMFCRHDLDSVVEVLLFAVARQVIIE
                     HTSMVDNLLCMLSVAILFCIRKFLFVSALDKKEPALKAINPVFKGAVSQQTPSQKQNE
                     KKETEAEEESRERILKAYSRNSLFE"
     gene            16496..17527
                     /locus_tag="ACZPCR_04785"
     CDS             16496..17527
                     /locus_tag="ACZPCR_04785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009662451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIR1230222.1"
                     /translation="MKKTGKIAAAAMAGVMALSMAGCSGNADSQTEAAKTEAESAQAE
                     DTSKEADASGDSYKIGVLQLTQHTALDKVNEGFVAAIEESGIDAELDQQNASGDQSAC
                     QTIAQMLVDSESDLIFAIATPAAQAVAGMTEEIPIVVSAVTDPADSGLVDSNEKPGRN
                     VTGTSDLTPVKAQMDLLQKLLPDAEKVGILYSTAEANSEIQVEMAKEALEDAGIQYEE
                     YTVSNTNEIQTVVESMVGNVDVIYTPTDNTIASGYATVAMVATENKIPTICGESGQVD
                     EGGLVTYGVDYYELGRMAGEQAVEILTEGADIASMPIGYMKDADCELQINEDTAAALG
                     LDMSVLEEE"
     gene            17527..18441
                     /locus_tag="ACZPCR_04790"
     CDS             17527..18441
                     /locus_tag="ACZPCR_04790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1230223.1"
                     /translation="MAGILSSLQGAVGQGVLWGIMVLGIYITFRLMDIADLTVDGSFA
                     LGGSVCAALVAGKGMNPVLALVVCLAAGMAAGAVTGILHTVFEIPAILAGILTQISLW
                     SINLKVMGKSNMNLGKAETPISWLKDSFGLTQNQAMIVTGLVVTVLVIVFLYWFFGTE
                     LGSAMRATGNNEDMIRALGGNTNRIKLLALMLSNGLVGLSGGLVCQGQNYADIQMGTG
                     AIVIGLAAIIIGEVLMGRLIPFYWKLIAVVAGSVIYQIIRAVVLRLGFDSDNMKLLTA
                     VIVVIALAVPVMATRYKQKMAYTEGGEE"
     gene            18441..19238
                     /locus_tag="ACZPCR_04795"
     CDS             18441..19238
                     /locus_tag="ACZPCR_04795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1230224.1"
                     /translation="MLTISNVKKTFNKGTINEKKALNGIDLHLDEGDFCTIIGGNGAG
                     KSTMLNMIAGVYPIDCGKIVIDGVNISREPEFKRAKYIGRVFQDPMRGTAANMEIQEN
                     LALAYRRGQRRGLGWGIKNQEKERYRELLTQLDLGLEDRMTSKVGLLSGGQRQALTLL
                     MATLQKPKLLLLDEHTAALDPKTASKVLSLTERIVESQNLTAMMVTHNMNDAIHIGNR
                     LIMMHEGRIIYNVAGEEKKNLKVEDLLRKFEQASGGQFANDRMMLAR"
     gene            19445..21130
                     /locus_tag="ACZPCR_04800"
     CDS             19445..21130
                     /locus_tag="ACZPCR_04800"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013272807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0070064 - proline-rich region binding
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HIR1230225.1"
                     /translation="MKEKQDLEHVDGLDTEDLELVDLDLEDLDQLPDEPVQQPEENLE
                     HQAEDGKAEKDEPPKKRRKRKGFYKEYAVIGVLALALLAVVIFAGSRLFGKKDDPALN
                     AKGKAVEETVSKEQEKAAKEEEEKKAVVDSYKNLGIVEVTGYLNVRETASPDADVIGK
                     LQDGGACEILDDSTEEWYHISSGGIEGYISAEYVLTGEKAREKAMEEAALRATITADS
                     LNIRKEPGTSAEVVGQALKGERYLVKSQEDGWIQISSGYISDDYATVAYGLNEARKLD
                     MRSMVLNLYDNLGISSVDSYLNIRSEPREDGDIIGKMTSKSAGEILETSEDGKWYKIK
                     SGPVTGYVSADYILTGQAAKDEALQVAELMAIVSTDRLNAREQPTQDSKIWTQISNNE
                     RYPVTEQLDGWVGIELDTSTAYVSTDYVDVRYALPEAVKFSPLDGNQSLRNKMVNYGL
                     QFVGNRYVWGGNDPHTGADCSGFVKYVYSHVAGITLPRTSREQARQGTPIKSSQMRPG
                     DLIFYANGGGTVNHVAMYIGNGQIVHAASRRSGIKISTWNYRTPYRIVNMLGD"
     gene            21309..22988
                     /locus_tag="ACZPCR_04805"
     CDS             21309..22988
                     /locus_tag="ACZPCR_04805"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0070064 - proline-rich region binding
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HIR1230226.1"
                     /translation="MGINKPDDYAARLLKARKRRNGKDPLKYFLIAAGCVIVILVIVL
                     AGKLAKGGRIDLGAGRTGKGPEIEGVFESEGSTEAAQGDLMDEDEELRKIDEQKAAVV
                     ESYENLGIVQVTGYLNMRESPDQNADIIGKMLNGSACEILDDSQEGWYQVTSGGLTGY
                     ISSEYVLTGDEAKTAAFDLVDQMAVITADKLNVRSEPNQDAQVLEQVLRNERYTIEEE
                     EGDWIKIPDGYISSEYVQERYALNEARKLDLRTMVLNMYDNIGISNVNNYLNIRKEPK
                     EDGKIIGKMTSKSAGEILETTEDGKWYKIKSGPVTGYVSSEYILTGQAAKDEALQEAK
                     LMAIVSTDRLNARTEPNTEAPIWTQISNSERYNVLSQQDGWVEIELDTTSAYVATDYV
                     DVRYALNEAIEFTPVEETSDTGSSGGKGGSGGKGSSGSKGSSGSGSSKRSQIASYATQ
                     FLGNPYVWGGTSLTNGADCSGFTMAVMSHFGVSLPHHSGSQANAGRAVSSSEMRPGDL
                     VFYTNSGGTINHVALYIGNGQVVHASNPSSGIKISRWNYRTPAKIVNVLGD"
     gene            complement(23175..24248)
                     /gene="citC"
                     /locus_tag="ACZPCR_04810"
     CDS             complement(23175..24248)
                     /gene="citC"
                     /locus_tag="ACZPCR_04810"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008398076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008771 - [citrate (pro-3S)-lyase] ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006101 - citrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HIR1230227.1"
                     /translation="MSEYRISEILPTDRRGMDQVNSLLEKEGIRRDKNLDYTVGLYDE
                     NYRLAATGSCFGNTLRCMAVDSDFQGEGLLGQLISHLTEYQYGRGNFHLFLYTKCSKA
                     MFFKDLGFYEIARSDGEAVFMENKKSGFADYLKRLVQETDESGAVPSRSGLPVGAVVM
                     NANPFTLGHQYLLEKAASACSLLHLFVVSEDASLVPFPVRFQLVKQGISHLSNVVLHK
                     TGSYLISNATFPSYFLKDEDSAICSHARLDVRLFQSIAKALSVSVRFVGEEPFSQVTG
                     LYNQVMISEAEAGGGPSVTVIPRLEQEGHTVSASLVRSLIHDGRLEEIRSLVPETTYR
                     YFTSEEAAPVVQAIQDSPQVIHY"
     gene            24350..25252
                     /locus_tag="ACZPCR_04815"
     CDS             24350..25252
                     /locus_tag="ACZPCR_04815"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009266195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0051117 - ATPase binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ClpP family protease"
                     /protein_id="HIR1230228.1"
                     /translation="MMYERLFTGKDKKEKAGCTKTPGSRKENVKRRKAMRELYEEKTG
                     YVRENHRGDDKTENSEKTESAQNSSQPQTGEKGEESARTEERIRETGQVLLDSGRQKN
                     RIHLLSVIGEIEGHENLSGSTKTTKYEHILPELAKLEDDDEVDGMLILINTVGGDVSC
                     GLALAEMIASLSRPTVSLVIGDSHSIGVPLAVASDYSFIVPTGTMMIHPVRMTGMVIG
                     AVQTYDYFEMIQDRILSFVAGHAQIAYDQLKRLMLNTEMLTKDLGTILVGQEAVKEGL
                     IDQVGGIREALKKLNELIEKKKKL"
     gene            25322..28756
                     /locus_tag="ACZPCR_04820"
     CDS             25322..28756
                     /locus_tag="ACZPCR_04820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003523893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015616 - DNA translocase activity
                     [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE family DNA translocase"
                     /protein_id="HIR1230229.1"
                     /translation="MAGTSRKKQETSEGPRSRAKNSRSKGASSGKKGTSSKTDRKTGK
                     SAGKADTKARGSSRRRDPEPEENSFILTEVAIIAVFALSVLLFLSNFHLCGVVGDFCR
                     EAMLGTFGKLGYLFPVLLCVGSCFYLSNRGNRRAVMKLAASAVTLLALCGLAQLIFGG
                     GYSEELKLFDYFKQDAVSGKGGGIVGGVLVTVLCSTVGTIGAYLILLVLFAIGVVCIT
                     EKSLVGAVRRGSGRAYRYAKDDMNRRREIYEERREERREERQRIREERARGIDMDAAT
                     LGEYSYEDSYDNSGEDLYEDSRRNSRGRYREDAIENDRYDSPEDYVLEPESKEPLNPA
                     DIFRGSIIMPGRGEQEELAEEPVERLEECRAEKAERHTGGIHAFAEQKASRSEAEPEH
                     PGAAEEAVHKEERREALKENQIGTQPAEHDRVFVSRRKGSAHSETLRRAEMPEFLPET
                     EELEPMQDSGFETPAREETLLKSIYAERDTRTFAELRMEEPSEDSGFGIENQEEEIYY
                     EPIDADEALAEEKSQTGGSPAEADGDFDTEDLAGRDALTAVKEQIREAGERAMAASDL
                     SWEEGNQIVTASGKVMETDADLMRKTLERKRHETKAASSDEEREHGNRESGRSLGREQ
                     TDRSAAAAVSPHPLSGRQETERRQEPVKKPQPEKKPYVFPPMDLLKKGRAVGGRSEQE
                     YKDTAIKLQQTLKNFGVGVTVTNISCGPAVTRYELHPEQGVKVSKIVSLSDDIKLNLA
                     AADIRIEAPIPGKAAVGIEVPNKETETVLLRDLLESENFKRASSKLSFAVGKDIAGQT
                     VVTDIAKMPHLLIAGATGSGKSVCINTLIMSIIYKSSPEDVKLIMIDPKVVELSVYNG
                     IPHLLIPVVTDPKKASGALNWAVAEMTERYQKFAKYNVRDLKGYNEKIKLIEDIEDEN
                     KPKKLPQIIIIVDELADLMMVAPGEVEDAICRLAQLARAAGIHLVIATQRPSVNVITG
                     LIKANIPSRIAFSVSSGVDSRTIIDMNGAEKLLGKGDMLFYPQGIQKPQRVQGAFVSD
                     QEVSRVVEFLAEEGLTTEYDPEVEKKMTSSFSGAGPDSAGDRDAYFEQAARFIIEKDK
                     ASIGMLQRMLKIGFNRAARIMDQLAEAGVVGEDEGTKPRKVLMSEEQFEELMEQGY"
     gene            28838..30301
                     /locus_tag="ACZPCR_04825"
     CDS             28838..30301
                     /locus_tag="ACZPCR_04825"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009214235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HIR1230230.1"
                     /translation="MLNDWLKELKYELVQGELEIPVKEVVYDSRKAGEETVFVCMKGT
                     NVDSHDFIPTVLAAGTKALVVEREVPGIPEDMTVLKVENGRNALALLSAARFGYPAEK
                     MVTIGVTGTKGKTTTTYMIKSILEACGKKVGLIGTNGAVIGDKHYATKNTTPESYILE
                     QYFDEMVKAGCEYMVMEVSSQSYLMHRVDGLTFDYGLFLNISNDHIGPGEHESFEEYL
                     YYKKQLLKHCKTAIVNEDDEHFDEIVKGAPSKIYTFSLERPADFEASGIRYVTASDFV
                     GLVFQMMGSYELEVKVNVPGRFNAANALAAVAVCSFFDLPKPKVSHGLENLKIDGRME
                     IAYKSSRMTVIVDYAHNAVSMESLLRTLRDYKPKRLVCVFGCGGNRAKERRYSMGEIG
                     GKLADFCIITEDNSRYEDVQEILTDIKVGLSMTSGTYIEIPDRRKAIEFAVSHAREGD
                     MIAIIGKGHEDYQEIKGVRYPFLDRQVVQETVEKLGL"
     gene            30357..31793
                     /locus_tag="ACZPCR_04830"
     CDS             30357..31793
                     /locus_tag="ACZPCR_04830"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007858173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HIR1230231.1"
                     /translation="MEHITVKEITEAAGGRLLAGDPSALVTEISIDSREAGKGCLFVP
                     LIGEKNDAHRFIMTALAQGTAAVFTSEHEETSEEVEESRQRWPEAAWIQVEDTRKALQ
                     ALGAFIRRRLTLPLVGITGSVGKTTTREMVAAALSAGYRVFKTPANHNSQIGVPLTLS
                     KISGEDQIGVLELGMSEPGEMEVIAEIAAVDMAVITNVGVTHIENLGSRENILREKLN
                     IQRGMNPSGPIFLNSDNDLLCRVSGWDGRETVYFGTGEQADYRAADISMENGCPSFTM
                     VHGDVRIPVTLSVMGEHNILNALAALAVADRNGVSLEAAAEKLREFGGFKNRQQVYEA
                     AGVTIIDDTYNASPDSMKAGIKVLSSFETSRRRVAVLADMKELGPDAGLFHRQVGEFL
                     AGEQVDALITLGELAEQIEEGARLRRPSLFAASFRDKEEMTRFLEEFLKPGDCVLFKG
                     SNSMKLGETALYFRNKGKEQAESAQARG"
     gene            31802..34063
                     /gene="priA"
                     /locus_tag="ACZPCR_04835"
     CDS             31802..34063
                     /gene="priA"
                     /locus_tag="ACZPCR_04835"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication restart helicase PriA"
                     /protein_id="HIR1230232.1"
                     /translation="MKQTFANVIIDISHEKVDRTFQYIVPEPLKDKIRAGVQVEIPFG
                     KGNSLRRGFVVEVTEKPEFDIDRMKEIAGISPDRVSVQSQLIELAWEMKRIYGSTMNQ
                     ALKTVLPVKQKMKRREKKTVRCRLTREELAEALKEARRRSYRARIRLFEAFLETEQIP
                     GEVVEHQLNITAASLKPLVESGAVEVARREVYRDPLKGLQKEAAQVKLNADQQAAADT
                     FWDSYKERLIQGPEGQKRLSRDRTWLLHGITGSGKTEVYMEMMDRVLREGRQVIVLIP
                     EIALTYQTVMRFYKRFGGRIAILNSRLSAGERYDQWELAMKGGVDIMIGPRSALFAPF
                     SNLGLIVIDEEHEGAYKSETMPRYHAREAAGIRARLSGADVVLGSATPSMESYSRALS
                     GEYGLLRLQKRASSDSRLAQAEVVDLREELKAGNKTMFSRSLSEQIQDRLSRGQQIML
                     FMNRRGYASFVSCRSCGEAVQCPHCDVSMTLHKNGRLYCHYCGYSLPMPKLCPSCGSP
                     YIAGFGTGTQKLEEMTKQLFPQARVLRMDADTTAKKGGHEEILSAFEAGEADILIGTQ
                     MIVKGHDFKNVTLVGIMAADLSLNTPDYRCAERTFQLLTQAAGRAGRGSQPGSVVIQT
                     YRPDHYSIETAARQDYEAFYSREIAYRRMMNYPPACRMSAVLFAAKDEAALEQFCRKA
                     SERISMILKGLSGPCQSIGPVNAPVYKVNDMYRKILYIKCENCDILDKIRDSMDFLTE
                     SGAGTVQVQYDVS"
     gene            34134..34613
                     /gene="def"
                     /locus_tag="ACZPCR_04840"
     CDS             34134..34613
                     /gene="def"
                     /locus_tag="ACZPCR_04840"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HIR1230233.1"
                     /translation="MAIREIRTIGDEVLRKECKLVKEMTPRTAELIEDMFDTMYQANG
                     VGLAAPQVGVRKQIVVIDVEDGNQYVLINPEILETSGSQTGPEGCLSVPGKSGTVTRP
                     DHVKVKALNENMEEYVLEGEGLLARAICHECDHLSGVLYVDKVEGELEDVSAEFEEE"
     gene            34648..35583
                     /gene="fmt"
                     /locus_tag="ACZPCR_04845"
     CDS             34648..35583
                     /gene="fmt"
                     /locus_tag="ACZPCR_04845"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HIR1230234.1"
                     /translation="MKLVYMGTPDFAVPALVSLVEAGHEVAAVVTQPDKPKGRGKAVL
                     MTPVKEKALSYGIPVYQPARVKKNEEFLNVLKEIQPDAIVVAAFGQILPREILELPKY
                     GCVNIHASLLPKYRGAAPIQWAVIDGEKESGITTMMMDVGLDTGDMLERVVVPLAEDE
                     TGGSLFDKLSMAGGPLILETLEKLENGTAVRTPQPEAGVTYAGMLDKSLGNIDWTKGA
                     AELERLIRGLNPWPSAYTHYGEKTMKLWAADVLPENFEGEPGQIVKVLKDRFLVKTGD
                     GTLAVKELQLEGKKRMDAGAFLRGFSLKEGEKLGL"
     gene            35696..36412
                     /locus_tag="ACZPCR_04850"
     CDS             35696..36412
                     /locus_tag="ACZPCR_04850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002603938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HIR1230235.1"
                     /translation="MYYGYGFYPMFDPTMILILIGVALSMAASARVNSTFARYSKVRS
                     MTGMTGAEAAQRLLNSQGIYDVTVRRVGGRLSDHYDPRSKTVNLSDDVYNSTSVAAIG
                     VAAHECGHAIQDAVGYAPLKFRGALVPVANFGSQISWPLILIGFFIGGFGSPMVQLGI
                     LLFSAAVLFQLVTLPVELNASSRAVKLLDATGILSGSEVDGTRRVLGAAALTYVAAAA
                     GSILQLLRLIILFGGRRDND"
     gene            36405..37790
                     /gene="rsmB"
                     /locus_tag="ACZPCR_04855"
     CDS             36405..37790
                     /gene="rsmB"
                     /locus_tag="ACZPCR_04855"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008398087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HIR1230236.1"
                     /translation="MTKTGSGKPANEGNRSASGAREIVLDVLLEILEKKQYSHLVLQR
                     ALAKYQYLDKQERSFIKRTVDGTLERLMQVDCLIESYSSVKLRKMKPVIRTILRMSVY
                     QICFMDRIPDSAACNEAVKLAVRRGFSGLKGFVNGVLRNVSRHKDEITWPDDSTAFCL
                     PQWIFSMWERQYGKEAARTMAESFLKERPLTVRMNLSLASREEIADSLESQGVKVRES
                     GFAEDVVFLSQVDYLESLDAFLDGWIQVQDLSSSLAGDAAGVKEGDYVIDVCGAPGGK
                     SLHIAELLHGTGMVEVRDLTEKKIALVEDNIWRSGFSNIEARVQDATEFDPDAQEKAD
                     LLIADLPCSGLGIIGRKPDIRYNVTEEQTRELAKLQREILSVVWRYVKPGGTMVFSTC
                     TVDPAENEENVRWILSQLPFEPVDLTDRIGDALAETLLEDTRKKGYVQLLPGFYPGDG
                     FFISVFRRKEE"
     gene            37815..38867
                     /gene="rlmN"
                     /locus_tag="ACZPCR_04860"
     CDS             37815..38867
                     /gene="rlmN"
                     /locus_tag="ACZPCR_04860"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dual-specificity RNA methyltransferase RlmN"
                     /protein_id="HIR1230237.1"
                     /translation="MERDGRADLKSMTLPELTEYLKDLGEKPFRAKQLYQWMHVKLAA
                     SLDEMTNLSKEMRGILKETAFYASLNPVDVRISQIDGTRKYLFELEDGNVIESVLMRY
                     KHGNSVCISSQVGCRMGCRFCASTLDGLERNLRPSEMLEQIYRIQRDIGERVSNVVVM
                     GSGEPMDNYDNLIRFIHLLTDENGLHISQRNVTVSTCGIVPRIRQFAEENLQVTLALS
                     LHAPNDEVRKTLMPVANSFALKDVLDACHYYFEKTGRRLTFEYSLVKGVNDNLDEARA
                     LADLLKGQHGHVNLIPVNPIKERDFKQSDRKAVEEFKQYLEKRGINVTVRREMGRDID
                     GACGQLRKSYIEKERT"
     gene            38873..39619
                     /locus_tag="ACZPCR_04865"
     CDS             38873..39619
                     /locus_tag="ACZPCR_04865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HIR1230238.1"
                     /translation="MKACALTDIGRVRPVNQDCRFATTEPIGPLSNLFIVADGMGGHK
                     AGDRASRLLIESLTSYIRNCSTRTPVEALNHGIAEANREIYEASLEHQELAGMGSTLV
                     AATIEDSTLYVANVGDSRLYLIEREGIRQITRDHSYVEEMVSLGQITRDSLEYKKQKN
                     YITRAVGIAKTVEADFFEVGLKEGDYVLLCSDGLSNMVDNSAMFRLVLLPGPLESKAR
                     ALIALANQNGGKDNIAVVLVDPQISEVDGL"
     gene            39619..42003
                     /locus_tag="ACZPCR_04870"
     CDS             39619..42003
                     /locus_tag="ACZPCR_04870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006775819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase domain-containing protein"
                     /protein_id="HIR1230239.1"
                     /translation="MLRPGMYLQNRYEILDQIGSGGMSEVYRAKCHKLNRLVAIKVLK
                     EEFSTDAGFVKKFKLEAQAAAGLSHPNIVSVYDVVDEGSIHYIVMELIEGITLKSYIT
                     KKGRLSSKEAIGIAIQVAQGIAAAHDQHIVHRDIKPQNMIISRDGKVKVADFGIARAV
                     SSQTIGATAIGSVHYISPEQARGGFSDSRTDIYSLGITMFEMVTGTVPFDGDNTVSIA
                     LAHLEQAVTPPSQLNPEVPVSLDRIIMKCTQKKPEKRYSDVYELIADLRHALVDPDDD
                     FVTEEPEVDTSSPTMVISNDELSQIKQARNTGPVVMNGQSSGMRAPSETGQHEKRHDR
                     EYGNGRRETYSRRDSRSGGGRSQEYDYDEYDDYQDEGSYDSYNDSYDGSYDRGRDRGA
                     GRDRGSDRMPASGSGSSGKKARKQKRDSDINPQIEKLLTSVGVVAAIIIVAVLITIFA
                     KLGGIFNSGSNGNNPAQTQTSGQETGLKDTETRVPDFIGLTEEEAEEKAKDSHLKLSY
                     GYVQSDEKKKGRVIEQKTAEGTVVDKQSTVKVIVGEGGEKESEEETKESHQIDLTVLG
                     LEALDGTNAKNLLEAKGLTVSLKQENSDTIPVDMVVRYEPQEADRGDEIELYVSLGPT
                     VSMVKVPDLSGMTEEEAGEALAEAGLLPAPEDQILTQKSDSVKRGTIISQTPLMDEEV
                     PEGSTVSYVVSEGRGKKYAAIVNDDYPLKDNFGPSGASTTITVEIVMVQTVNGQKRTT
                     TVMDARNMKGDVTLPVHYELTGADGVLTGELQIWDLTNDRILKTYPLEFMEVDA"
     gene            42004..42882
                     /gene="rsgA"
                     /locus_tag="ACZPCR_04875"
     CDS             42004..42882
                     /gene="rsgA"
                     /locus_tag="ACZPCR_04875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003523903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HIR1230240.1"
                     /translation="MTGKIVKGIAGFYYVHDGQQKVYECRAKGVFRNRKIKPLVGDNV
                     EFEILDEEAGTGSIVSILERKNSLIRPAVSNIDQALVVFAITEPMPNLNLLDRFLVMM
                     ERQNIPAVICFNKIDLSSREEMERLRSIYAPAGYEIHFISTYEEAGLQEIHRLIQGKT
                     TVLAGPSGVGKSSLTNFLQPEANMETGVVSEKIKRGKHTTRHSELFFVEENTYMMDTP
                     GFSSMYIEDLKPEELKDCFPEFAPEEDGCRFLGCVHVGEKVCGVKEAVKVGTISRSRY
                     ENYLLLYQELKDKRRY"
     gene            42882..43544
                     /gene="rpe"
                     /locus_tag="ACZPCR_04880"
     CDS             42882..43544
                     /gene="rpe"
                     /locus_tag="ACZPCR_04880"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006775817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HIR1230241.1"
                     /translation="MMIRLAPSVLGADFSRLGEEIQAVDRAGAQYIHLDVMDGTFVPS
                     ISFGMPVIERLRPVTDRVFDVHMMVEEPGRYVEDMKKAGADLICVHQEACRHLDRTVN
                     QIKELGLKAAVALNPATPVSTLSCILDQLDMALIMSVNPGFGGQKFIPYTLEKIRQLR
                     RMSDERGLNLDIQVDGGVGLGNVRQVIEAGANVIVAGSAVFKGDAAANTKAFLEIFKE
                     YE"
     gene            43537..44205
                     /locus_tag="ACZPCR_04885"
     CDS             43537..44205
                     /locus_tag="ACZPCR_04885"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006780429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HIR1230242.1"
                     /translation="MSRMEGETCLIITGGNLNLDFAEQFLKHRSYGCVIAVDGGLEAA
                     AALGVCPDEIVGDLDTVNPALFDSYRRKPGIELEIHRPEKDETDTELALLTAERKGFH
                     AVHLLGALGGRMDHALGNVQLLNQCLQNDVHAEIYDEKNRIYLAGPGRTEFAREQAYG
                     QYISFLPLTESVEGITLTGFKYPLSNKTIHLGTSLCISNELTGEKGSLEFQKGILICI
                     ESHD"
     gene            44333..44920
                     /locus_tag="ACZPCR_04890"
     CDS             44333..44920
                     /locus_tag="ACZPCR_04890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002603946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HIR1230243.1"
                     /translation="MIRNNDKAYKIAMTGLMAALSYVVFTFGQIKLTLPGGDATSIHL
                     GNAVCVLGALLIGGFWGGLGGAIGMTIGDLLDPVYVVYAPKTFILKLCIGLITGFVAH
                     RIGKISVSTDKKHILKYVILASAAGLLFNMAADPLFGYYYKLLIIGKPAAELALVWNI
                     ASTSINAVISAAASVLIYMAARPALHSAGLLLRLS"
     gene            44928..45779
                     /locus_tag="ACZPCR_04895"
     CDS             44928..45779
                     /locus_tag="ACZPCR_04895"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007717974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008478 - pyridoxal kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009443 - pyridoxal 5'-phosphate salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HIR1230244.1"
                     /translation="MMNETGQKKIAMINSMAGYGRCSITAAIPVLSALKVQCCPAPTA
                     ILSNHTGYPSCYFDDYTEGLAPYLEEWKKLQFSFDAVMTGFLGSAGQVRTAVDFLMEV
                     KPQGTKVLVDPVLGDNGTLYRTCTQELCEEMRELIQYADVITPNLTEACLLTETPWSE
                     TGWSKNRLADLAYKLLFMGPGAVVLTGAAKSHSIINVVLERGKEPVFFTGKRVETSRH
                     GTGDVFSAVLAGEMVHSVPLEEAVRRAATFTRKCVERSEELQIPEKEGLCIEECLPYL
                     FRLSRRD"
     gene            45934..47211
                     /gene="serS"
                     /locus_tag="ACZPCR_04900"
     CDS             45934..47211
                     /gene="serS"
                     /locus_tag="ACZPCR_04900"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HIR1230245.1"
                     /translation="MLDLRFVRENPEIVKQNIRNKFQDSKLPLVDEVIELDAQNRAVK
                     KEADDLRAGKNKIAKQIGGLMAQGKKEEAEELKKKVGEDAARLAELETLEKELSEKIT
                     KIMMTIPNIIDPSVPIGKDDSENVEIQKYGEPVVPDFEIPYHTEIMERFNGIDLDSAR
                     KVAGNGFYYLMGDIARLHSAVISYARDFMIDRGFTYCVPPFMIRSNVVTGVMSFAEMD
                     AMMYKIEGEDLYLIGTSEHSMIGKFIDTVLKEEELPKTLTSYSPCFRKEKGAHGIEER
                     GVYRIHQFEKQEMIVVCKPEDSMKWYDKLWQNTVDLFRSLDIPVRTLECCSGDLADLK
                     VKSVDVEAWSPRQQKYFEVGSCSNLGDAQARRLKIRVNGENGKYFAHTLNNTVVAPPR
                     MLIAFLENNLQADGSVRIPEVLRPYMGGKAEIR"
BASE COUNT        12460 a        10488 c        14155 g        10261 t
ORIGIN      
        1 aatttaaaga tggatatgta gtaaacctag gaataggaat acagaggaaa aaaccagaag
       61 aagaggaaac gcaggctctc tcttctcctg atcaactatt attcactgga aggagaggtg
      121 gaggatccct actacctttc cgtgaggatt gccatagaaa gacgtgctgc agagcttggc
      181 tgcaggcttg tcagtatttc agaaaaggat gaattccggg tgtcaggcat tgacggagtc
      241 atctgcctgg gaacctttgg aacagaggaa ctgaaacgga tcgacgagct ggaacggccc
      301 accatctttg tggacagcaa tcccaattac gacaaatatg attccattgt gtttgacctg
      361 cgcagggaga ccaggcggat tctcgattac ctgtgggaga aggggcacag acgaattggc
      421 tttatcggcg gaaacgatat ggaagggcct ggaacatttg cggagacgga caagaggacg
      481 ctggagtacc gggcatttat ggaggagaaa aaggaggagg gcgtcagcta cgagcggatt
      541 ggagcgttca cttcccgcat gggctttcgg ctgatgaacg agctgatggc tctgcccgag
      601 cctccgacgg cagtttttgt ggccaatgac tcgctggcag tgggctgttt aaatgccatc
      661 agccgggccg ggaagaggtg tccggaggac ttcagcattg tgggctttaa cgatattccc
      721 acagccaaat atatggttcc accgcttacc accatgcgcc tgtacatgga ttttatgggg
      781 gagagagcgg tggatctgtt aagcgaccgg attctgacga agcgggagct gcctgtccag
      841 gtgacgcttc cggctaagct gatgatccgg gagagcgtga aggatctcac agccgattcg
      901 tcattataac gaaaaatttc tctgtatttt gtgcggtgtg ccgtggaaaa tccggcagaa
      961 gttttatata ctgaatgcat ctgaatgctg aacattattg atagaaaagg agaacccata
     1021 tgtctacagt taaattagaa cacatctgta agaagtatcc taacggcttc gaggctgtaa
     1081 aggatttcaa cctggagatt ggcgacaagg agtttatcat tttcgttggt ccgtccggct
     1141 gcggaaagtc tacgactctg cgtatggtag cgggactgga ggacatttcc ggcggcgacc
     1201 tgtacattga cggaaagaga atgaacgacg tggagccgaa ggatcgggat atcgccatgg
     1261 tattccagaa ttacgccctg tatccgcata tgaccgtgta cgagaacatg gcattcggct
     1321 taaagatcag aaaggttccg aaggatgaga tcgacaagaa ggtgcatgag gctgcgaaga
     1381 ttctggatct ggagcacctg cttgacagaa agcccaaggc gttatccggc ggccagagac
     1441 agcgtgtggc catgggacgc gccattgtaa gaaatccgaa ggtattcctg atggacgagc
     1501 cgttatccaa tctggacgcc aagttaagag gccagatgcg tatcgagatt tccaagctcc
     1561 accagaagct gggcacaacg attatctacg ttacccacga tcagacagag gccatgactc
     1621 tgggaaccag aatcgtcgtt atgaaggacg gagtggttca gcaggtggat acgcctgaga
     1681 atctgtacga caagccgggc aataagttcg tagcaggctt catcggagcg cctcagatga
     1741 acatggtaga cgcagaggtg aaggaggatg cagagggcgt tcatcttgta ttctgcggac
     1801 agagcattaa gatggatgag aagagagcag ccatcttaaa ggagaaggga tacatcggaa
     1861 agaaggttac cctgggaatc cgcccggagg atctccacga tgagtctgac agcgagcgcg
     1921 gcaacaagga cgcctgcctg aacgccacta tccgcgtata cgagatgctg ggcgccgaga
     1981 cgttcctgta ctttgacatg gatacagcta catggacagc cagagtgaat ccttctgtcc
     2041 gtgtaaagcc gggcgaagcc attaagctgt acatggatac agagaagatt cacgcgtttg
     2101 atacggagac tgagaacgca atttttaatt aattttaaaa ccgtctgaat aggaaaatga
     2161 ggcggtgaaa aggggggagg atgctgccgg ggcagtatcc tcttttccgc ttatagacgc
     2221 aggattagga ggaagcggct tggtatcgaa gagagcgctg aaacatgtgc tgggggaaat
     2281 cagggacgcg tccgggcttt cgcttgccct gtttggagga aagggagagc ttctggcgct
     2341 ttcagaggga gaaggacagc tgtttgagga gctggagaag gaaggtctcg tttcggaccg
     2401 cttaaaagaa tatgtaagat ccctggcgga ggggggagag aaaacctggc agcggggagg
     2461 cgtgtgcttt ctcaggacgg ggaatgagag aggggaaggc tttgtgttag ccggaacagg
     2521 taaggaagac gttctgcctc ttctgcgcct gtcggcagtc gctctctcag gtcttttccg
     2581 gcgtcaggag aaacgtcagg atcgggacgt ttttttccgc cgcctgattc tggggcagct
     2641 gcttcccggg gaggtttcag aacaggcccg gctgctccga ttggacggca gggcccggcg
     2701 ggctgtattt ttaataaaag taagggagga tggctgcgat acggttctcg atattcttta
     2761 tcccctttac gcaggtccgg caggaggcgt tctgtttcag gcggagccgg ggagcttcgt
     2821 gtacgtcaga accctggggg agaaggagga tacggccaaa ctggaggaga taggaaaaaa
     2881 catgattgat gtgattaata cagagggaat ggaggacgcc tatctctcct tcggaatgcc
     2941 ggcagaagaa ctgtcttttt tgaaccgatc ctatgaggag gcctggatcg ccatgaaggc
     3001 gggccgcatt tttttccggg aaaagcatgt gatttcctat gacagactgg gaattggacg
     3061 gctgatttac agccttccca tgcctttgtg cagacagttt ctgggggagg tattcgccca
     3121 ggcagatcca ggggcgtttg acgaggaagc gctgactact atccgccagt tttttgaaga
     3181 ttctctgaat gtggcggaga cggcaaggca tctttatatt cacaggaata cgctggtgta
     3241 ccgtctggac aagattcaga aaggcctggg gctgaatata agaaacttcg acgacgccat
     3301 gatgctgcgt ctgggactga tggtttatga gtatgtgaga gaaaaggaac aggaagagga
     3361 aaaggagaga aagaccgatg gtagaacgga tgtttaacac agacaatcac ttctggcaga
     3421 cagtgggaaa ggcgggggat ctgattgctt tgacatttct caccctgctc tgctcccttc
     3481 cgctgatcac ggcgggggcg gccttctgcg ccatgaacta tgtatgcttt aaaatgctgg
     3541 agcacgataa tgagggaacg atcagaaact ttttccacag ctttcggcag aatctctttc
     3601 agggagcggc gctctcgctg attatggggg cagcaggctt cctgctctgg tatgacggct
     3661 ggtttctgac caggtacttt gacggacagg aggggggcgc catgctctac gccggctggg
     3721 ccgtctacat ttacctgatt ttcttttacc tgatacttgt actgtatgta tttccacttc
     3781 aggccagatt ttataacccc ttagccgtta cttttaaaaa tgcagtcata gcaggattta
     3841 agaatctccc caagacgctc atgatgcttg cgggagatgg agccatggca gtcctgaccg
     3901 ttctgtgttt taaaaccttt ccccagatcg cgtttcttcc ccttctgacg gcccttcccc
     3961 tgtgcgtctg gtaccacagc tgggtactga gagatctgct gggactggtt ccgggaaagc
     4021 tggatctgcc agtatctgac gacaaggaag aaaggaagga ggaacgctat gagtgatttt
     4081 gctggggagc agtataaaaa ggcgagaaaa gctggaatta aggccttccg ggaggcggga
     4141 ggaaagggca gatatcccta tctgacgtct ctggacgaga tccttctcca cacaaaaaca
     4201 gctggcacag aggatctggg cgtgtgcgag atccctctgt ccagagtcac gggaaccaag
     4261 acggcctccc gctcggagag ctttgcctgg aatttcatgc cccttcttcg ggaaaaaacg
     4321 gagttttcag gaaagtggga gaggctttat gaggcccaga tggaggaggg aatcagggag
     4381 ccggtaaagg tttacgaata tatgcaccat ttttatgtgc gggagggaaa taagcgggtc
     4441 agcgtgatga aatacgtggg agccgttaaa atcacggctg acgttaccag gatctttcca
     4501 aagagggacg gaaagaaggc ttacgaggca ttttaccagt atgcggcgtt taacagggcc
     4561 acaggactgt tcgagctgct gttttcggag ccggatgctt accagaagct ggccgcccgg
     4621 tttgaggaga ctctggcaga gcggtggaaa gaggacaaaa ttaaggaact tcgggctgcc
     4681 tttgggagat tctgcagctg ctatgagaaa aaggcgagag cggacagcct gacagaggag
     4741 agcgacgcgt ttttcgtgta tctggaggtg tttggctatc aggggcttct cacagacagc
     4801 gaccgtcaga ttcgggaacg gatggagagg gcctgggagg agatgaaact ggccggacag
     4861 aagaagaagg tggccctgat cgaggagcac agggaagcag aagaagggaa aaacagtctg
     4921 tttggcttcc tgcacggggg agagaaaagg cccctgcgca ttgcttttat caatgataaa
     4981 gactccagaa cctccgcctg ggcctacggc caccggctgg gctggcaggc cttaaaggag
     5041 aaatatggaa gtcaggtgaa aatttctgtt tacaatcact gcgatacacc ggaggctgtc
     5101 agagacgctc tggccaaggc agtactgcag aaaaacgata ttatttttac aacagcgggg
     5161 cagatgcggg ctcaggcgct ggagacggct gtcaatcacc cggaaatcaa atttttgaac
     5221 tgttccgtca acgcctccta ccgctccatc cgcagctatt atgccagaat gtacgaggcg
     5281 aaatttattc tgggcatgac ggctgccgct ctctgcgagg acggcaggat cgcctacatt
     5341 gccgattatc ccgtatacgg agctgtggcc aacattaacg cgttcgccat aggcgcccag
     5401 atggtgcggc cgggagtgaa gatctatctg aaatggtcca accttaaaaa gggcgattgg
     5461 aaagcggaga tcaaaaaatc tggatttact atggtttcag ggcctgatct gaagctgccg
     5521 tcagaggaaa gccgcctctt cggcctgttc cggtacagcc agaaaaaggg agactatgaa
     5581 aatctggcca tgccgttcat tgactggggg cggtattact gtcttctgac agagtcggtg
     5641 atggatggaa actttgattc cagggagttt acaaagacag ggcaggcagt caattatttc
     5701 ctgggcatgt cggcccaggt agtgagcgtg atcttttcct cccgcgtccc ctactcggtg
     5761 agaaaaatgg cggatgtgtt tgaggaggcg atgatccagg gcagattttc gcccttcgac
     5821 ggagagatcc ggacgaaaaa agggtggttg aaggggggct gacagcggtt ccctggatct
     5881 gttccagatt gtgaaaatgg actggctcaa cgacaatgta ataggaaaaa taccagggat
     5941 cgacgctttc aaggaggacg caagagagct tctctctgcc ctgggagtgg aggcggccag
     6001 aacggaggag ggaggaacac catgaaaatc ttgattgtag ctgacgagga gtcgaaggcc
     6061 ctctacgatt attatgacag ttcccggctg aaggatatcg atctgatcct gtcctgcggg
     6121 gatctgcggg cctcctatct ggagtttctg gtcaccatgg gccgggcgcc tgtcctctat
     6181 gtcatgggaa accatgacga caggtataag gcgaatccgc cggagggctg cgtctgcgtg
     6241 gaggaacggg tttacaatta taagggcctt cgaatcgcag gcctgggagg ctgcatgcgg
     6301 tacaagccgg atggaattta cctgtacaca gaggaggaac agcgaaggcg cgtccagaag
     6361 ctgaagcggc agctgcagcg gtatcacggg gcggatattt tcctcaccca cgccccggcc
     6421 aaggggctgg gagacggatc ggattttccc catcagggct ttgagtgctt ccatgaaatt
     6481 ctggatgaat ttcatcccaa atatctgatt cacggacacc agcacttaaa ttacggatcc
     6541 ggtgcccgca ggctggagaa ggggcctacc gccatcatca acggatacgg ttcttatacc
     6601 ctggagatcg ggccggagga atacccttcg gagtatgaga atacaggttc tctgattttt
     6661 gatttgtata ataaactgag gcacagataa atcttgtccc agaacatgtt ttgtgataga
     6721 cttaggagca aaagggcctg cgcggcaggc cggactagga ggaaagacag catgagcaaa
     6781 aagcgttcaa tcgaaactac ctgcatccag ggaggatggc atccggagaa tggggaggcg
     6841 agagttctcc ccatttacca gagcactaca tttaaatact ctaccagcga acagatggga
     6901 cggctctttg atttggagga gaacggctat ttctatacga gacttgccaa tccgactaac
     6961 gacgccgtag cggagaagat ctgcgagatg gagggcggag cggcggccat gctgacttcc
     7021 tccggccagg cggccaattt ctattccgtt ttcaacatct gctcggcagg cgatcatttc
     7081 atctgcgcgg ctactgttta cggaggaacg tccaacctgt ttactgttac catgaagaag
     7141 atgggaatcg aggtcactct ggtagatccg gagtctactg atgaggagct ggacgcggcg
     7201 ttccgcccaa acaccaagtg cgtattcggc gagtctatcg ccaacccggc gctggtggta
     7261 ttagacattg aaaaatttgc cagggcagcc cacagacacg gcgttccgtt aattgtggac
     7321 aatacctttg cgacgcctat caactgccgc cccttcgagt ggggagctga cattgtaacc
     7381 cactctacca gcaagtacat ggacggacat gccatgagcg taggcggatg cattgtggac
     7441 agcggaaatt ttgactggga agcccacaag gacaaattcc cgtgtcttac cgagccggac
     7501 gcttcctacc acggcgttgt gtatacagaa aaatttggaa agggagctta tatcacaaag
     7561 gccaccgctc aggtcatgag ggatctgggt tcaattcagg ctcccatgaa cgcgtttctt
     7621 ttaaacgtag gcctggagac tctgcacctg cgtgtgccgc gccactgcga gaacgcgctg
     7681 aaggcagcga aatacttaaa gtccagagag gacgtggcgt gggtaaatta tccgggactc
     7741 gagggagaca gatattacga gctggcacag aagtatatgc cgaatggaac ctgcggcgtt
     7801 atttccttcg gactgaaggg cggcagagag gcggcaggcg tatttatgga taagctgaag
     7861 ctggctgcca ttgtgactca tgtggcagac gcccgcacct gcgtgcttca tccggccagc
     7921 catacccacc gtcagctgac agacgagcag ctggcagagg ctggagtcga tccatccatg
     7981 atccgcctga gcgtgggaat tgagaacgcc gacgatatta ttgaagatat ccgtcaggct
     8041 ttagaggact aacagccctt aaacaggaga acagtcaaat gaaaaagaga aaaaagctgc
     8101 tgcggcttgt gtttggcaga accacctttg tggtgctgtt ccttctgatc caggtgggaa
     8161 tcctgctgat gggatttgcc tggctggaag agtacatgct ctatttctac ggggcgtctg
     8221 tcattttgag cgcggtaact ctgatttaca ttatcagcgc agatgagagc acttccatta
     8281 agctgtcatg ggtcgtcccg attcttgttt ttcctgtatt cggaacgctg ttttatctgt
     8341 tcgtgcggct tcagatcggc acgaagctta tcggccacag actgaagatg acgtctgccg
     8401 agacagcgcc gtatctgaag caggacacgg agacagcaga gcgctttaac gagatgagct
     8461 ccagccaggg caacctggtg cgctacatga accggtttgc cggctgtccg gtctatcaga
     8521 atacagcggc ccagtatttc cctctgggag acgatatgtt cgtagagatg aagcgccgcc
     8581 tgaaagcggc gaagcacttc atttttatgg agtattttat tgtggagagg ggagaaatgt
     8641 ggaacagcat cctggagatc ctggaggaaa aggtcaggga gggtgtggag gtccgcgtta
     8701 tgtacgacgg catgtgctgc ctgatgctgc ttccctattc ctaccctaag acgcttcggg
     8761 aaaaggggat taaatgcaaa atgttttccc ccatccggcc cgccctgtcc acccaccaga
     8821 ataaccggga tcacagaaaa atctgcgtca ttgacggtca tacggccttt acaggcggcg
     8881 tcaatctggc agacgagtac attaacagaa aggtacggtt cggccactgg aaggacacgg
     8941 ctgtgatggt agagggagac gcggctgttg gctttaccat gatgttcctc cagatgtggg
     9001 gagtgacaga gcaggagaag gagcgctatg aaagctactt aaagcctgcg gactaccggc
     9061 ttccaaaaga cgctgacgct tccggattcg tgattccata cggcgacagt cctctggata
     9121 aggaaaatgt gggagagcag gtctacctgg atattctggg ccatgcgaaa aaatacgtcc
     9181 acattatgac gccctatctg attctggacg atcagatgat caacgctctt cagtattccg
     9241 caaagagggg agtggagaca atcatcatca tgccccatat tcccgacaag atgtcagcct
     9301 atctgctggc ccgctcctac tatgaagagc ttttgacagc cggggtaaga atctttgagt
     9361 atacgccggg ctttgtccat gggaaggtct tcacctgcga cgacgagaag gcagtagtag
     9421 gaaccatcaa cctggatttc agaagccttt accttcattt tgagtgcgcc gcttactttt
     9481 ataagcaccc ggtggtggcc caggtggagg atgactacca gaaaaccctg gaaaagtgcc
     9541 aggagatcac catagcagac tgccggaatt tcccattctt caagcgtttt atgggaaagg
     9601 ccctgcgcct gttcgctccg ctgatgtagg gagtttgaca gatttttaat gacagaggac
     9661 tggcagaagt tttcagcggc tttaagtgaa gcgtgaaaac ttctgccagt cctttttgtc
     9721 attttttccc ttccgcttgc attttccaga acgacccttt atattaatgt atagagattt
     9781 taacaaaact ctaacacaat actaaaaagg ggtggaagga tgacagaagg agctctggtg
     9841 ctggaagggg gttctctgcg ctgtctgttt acagcgggag tcctggacgt gctgacagag
     9901 gaaaatatac aattatccta tgtaaacggt gtatcggccg gaactatggc cgggatgaat
     9961 tacatcagcg gccagaaggg cagaatgctg gaaattagcg agacgtatct gcacgacaag
    10021 cggtacatgg ggatgagaag cctcataaag aacaggctgg tattcaattt tgattttata
    10081 ttcggtgagc tgtcggatga gctgattccc tttgactatg aagcgtttta cagctctcct
    10141 cagaagtttg aggctgccgc tactaggtgc aggacgggaa agacggagtt ttttgaaaaa
    10201 agccagtgca gcgatatgat gaaggcggtg caggcttcct gcagtatgcc tcttttatct
    10261 aaaatggtga cagtggatca caaaaaatat ctggacggag gcatttccct gcccattgcc
    10321 taccagaggg ctatggatct gggatataaa aaaattgtcc tggtgcttac cagaaaccat
    10381 ggataccgga aaaagccttt aagctctctg gctgtcaggg cttataaccg gtattttgag
    10441 ccgcttccgc agctgaaagc cgctctgttt gaagtgccgg accggtataa ctggatgcag
    10501 gaggagattg accgcctgga acaggaggga cggattttcg taatccgccc ggaacgtccc
    10561 gtccgcgtct cccgtctgga gcgggatctg aaaaagctgc aggcgctcca ccaggagggc
    10621 agggaaacgg ccgttaagct gcttcctgcg cttcgcagct atctggaaat ctgacaggga
    10681 caggaggata tggaaatgaa atatattgat atgcactgcg atacgatccc gcgcctctgt
    10741 catccgaagg caggggagag gggagagacg ctgagaaaaa acagcggaca cctggatctg
    10801 gagcggatga aacagggaaa cgccctggcc cagtgctttg ctgttttcac agatctgaaa
    10861 gcgtatccgg atccctatgt ccgtgccagg gagattttgg cccgttttaa gaaagaaatg
    10921 gcagaaaacg gcggtatgat tgcccaggcg tttacggcag aggacatttt aagaaacgac
    10981 agggaaggaa aaatgtcggc cattctcacg attgaggagg gggcggtttg ccagggaagt
    11041 ctggaacgcc tgcgggaatt ttacgaagag ggtgtcagga tgatgactct cacctggaat
    11101 tatcccaatg atctggcgtg gcccaaccgc ctggatccgc agaccgggca tatgactcct
    11161 gagacggaaa gggggctgac agagaaggga gccgccttta tcgaggagat ggaacggctg
    11221 ggaatgatca ttgacgtatc ccatctggga gacgccggct tctgggatat cgcgaagcgc
    11281 gccagaaagc cttttatagc cagccattcc aattcgcgaa gcgaggccgg ccatgtgaga
    11341 aatctgacgg acgagatgat ccgggcgctg gcagaccggg gcggcgtcat gggaatcaat
    11401 ttctgcggcg tctttctgaa cagccggaac ggaaattctc cagacggagg agacagccgc
    11461 gtttctgata tggtgagaca catgaagcat atccggcaga cgggaggcat tgaatgtatc
    11521 ggcctgggat cggattttga cgggatttca ggggatctgg aggtggattc cccggcggct
    11581 ctttaccgga ttgccgatga aatgtcgcgc cagggattta ccggatcgga gatagatgca
    11641 gttttttata agaacgttct gcgcgttttt acagaaattt tacattaagc tatagactgg
    11701 ctttacatag agctgatata gttaaaccat acttttacaa taagaggaga aaaatcatgt
    11761 cgatatcgga tttgggaatg ctgtttcagt ttgccggcgg ccttggaatg ttcctgtacg
    11821 gaatgaatat catggctgac ggacttcaga gatccgccgg cagccgcatg cagcatatgc
    11881 ttggggtgct gacgaacaat cgtctcatgg gagttctggc aggcgcggca gttactgcca
    11941 ttattcagag cagttccgcc actaccgtta tggtggtcgg ctttgtaaac gcaggaatta
    12001 tcaatctgtt ccaggcgacc ggagtaatca tgggagccaa tatcggaacc accatcacca
    12061 gctggattgt atccatgagc gagtggggcg aggtgttaaa gccggagttt ttcgcaccgt
    12121 ttttattctt tatcggcgct tttctggtgc ttttcacaaa gagcaataag aaaaaagagg
    12181 gcggcgagat catgatcggt tttgcccttc tgtttatcgg actttccttt atgtcctcat
    12241 ccattgagcc atacagagac gcgcctattt ttgcccaggc cttccagact cttggaaaga
    12301 acccgatttt aggcgttttg acaggacttg tagtgaccgc tatcatccag agcagttctg
    12361 cgtctgtggg aattcttcag actctggcct taaacggaat ggtaaactgg cagtcggctg
    12421 ttttcattac cctgggacag aatatcggaa cctgtgtgac ggctctttta tcagcggtag
    12481 gagccagcag aacggctaag agagcggctg tcatccatct gctgtttaac atttttggaa
    12541 cgattctatt tggaactgtt atgtttgttg tcttcatgct caaccccgcc ttcgcggcat
    12601 ctacagcgga cagcgtggga atttccattt tccacacagt gttcaatgtg tccaacacca
    12661 ttctgctgtt cccgtttgcg ggaatcctcg taaagacggc ctgcgccctt gtccgggaca
    12721 gcaaagagga agagaagacc ggggatgtgg agggagatat tctccgccat ctggacgacc
    12781 gtattctgga atctccgtcc tttgccattg agacagtgga aaaagaagtc atcaatatgg
    12841 gacgtgtggc agcggccaat ttaaagattg ccacggcggc tctgacggat cggaacgaat
    12901 ccttctgcca ggaagtattc gataacgaga agaagctgaa ccacctggat acggagctga
    12961 ctgactatct ggtaaagatt aacaatctgt ccttaaacga cagccagcat ctgattgtaa
    13021 aaaacctgtt ttatactatc ggagacgtgg agcggattgg cgatcatgcg gagaacctgg
    13081 cagagctggc ccagattaat atcaaaaata acagagagtt ttctgagagc ggtttaaacg
    13141 atctgaagaa gatttctgag gctgccatta aatcggtgga gtcagcgatg gagtgccggg
    13201 aggacaggga gctttccaag gtccgtcaga cggcgcgcta tgaggaggaa gtggacagcc
    13261 tggaggagga gctgaaggag cttcacatgg agcgtctgtc caaccacgaa tgcaatacaa
    13321 aaagcggcgt cattttcctc gatgctgtca gcaactatga gagaatcgca gaccatgcca
    13381 gaaatatcgc cggctatgtg aaagaggaga tagaataatg atgaagcacc tgatctatgt
    13441 gacagaagac gatgaaaata tcagaaatct gatttgcgtg gctctggaaa gctttggcta
    13501 tacaacctgt gcctttgaga cagccgagga ggctctggaa gcagtgaggg gggtggaggg
    13561 aagcctcccc tccctctttg tgtttgactg gatgcttccc ggaatggacg ggatggcggc
    13621 tgtagccaag ctgaaggcgt cgcctgacac cagaaaaatt ccggttatga tgctcactgc
    13681 caaagacagc gagctggacg tggtggcagg ccttgacgga ggggctgacg actacatgac
    13741 aaagcccttt gggattttag agttttccgc cagaatccga aatctcttaa aacgcttcgg
    13801 cgaggagaag gaagaagaca agagtcttgc agtgggagat atttccattg atctggaaaa
    13861 gcgcgaggtg aagaataagg gagaggctgt ggagcttacc ctgaaggagt atgagctgct
    13921 ctgctatctg atggaaaata ccaaccgggt cgtgaccagg gaggagctgt tagaccggat
    13981 ctggggctac gattatgacg gagagacgag aacgctggac atgcatatca aaacgctgcg
    14041 ccagaagctg aaggaatcag ggcacagcat taagacaatc cgcggagtcg gatacaggat
    14101 cagctgacag gaaaggaaga caggggaacc agggaaatga aaacagccat attcagaaaa
    14161 tttatccagc ttcttctgct ggcgctgctt ttaaacacag cgattctcta catagtgaca
    14221 ggaagcgtca ttctgaataa cagccggaat gatatggtat ttattctgga taccatagac
    14281 agtgccttcc actatgaggg ggatctggaa gcccaggcgg agcggatttc ccagtctgcg
    14341 aatttaaatg aaagccgcct taccatcata gatccaaacg gagtggtccg ggtagataca
    14401 ggcgtgaagg atgcgtctga gcttgacaac cacatgcagc gagaggagtt tcaggaagct
    14461 gtaaagacgg gggaaggaga tgacagacgc cgctctaaaa cgctggggaa ggagatgctg
    14521 tacgtggcca tacagtcctc ctactctgac tgcatcctgc ggctggcagt tccctatacg
    14581 ggaatgcagg attacattaa aatgctgttt ccggcagttc ttctgagctt ttctgtggct
    14641 ctcatcggtt cggcgctgga ggcggatcgg ttttcacagt ccattaccaa gcccctgctt
    14701 gagatctcca aagaaatgat taaggtaaac ggagattaca cagatttcca ttttgaacga
    14761 tgcggctacg aggagatcaa catcattgcc gacacaacga ccagaatgtc gaagaatgtc
    14821 agagattatt taaaccgcct ggagcaggaa aagcagatcc gccaggagtt tttcagcaat
    14881 gcgtcccatg agctgaaaac gcccattacc tctatccgcg gctatgtgga gctccttgac
    14941 acgcccatgg ctgacaatcc tcagatgcgg ggcgattttc tcagccgcat taaaaaagag
    15001 gcggtccgca tgaccagcct gatcgacgat atcctcatga tttcccgcct ggagacaggg
    15061 ggaattcaga cagaacttcg ggagctgtct gccggagaac tggcgcggga ggcggtttcc
    15121 tctgtggagg gaatggccag agagcgtaga atcgagatag agacagatgt ggaggaattt
    15181 tatatctgcg ccgacggaag acagatggag gagctgttta cgaatctttt gagcaatgca
    15241 gtaaaatata acctggacgg agggaagata tggctttccc tgaaacggaa gggaacggat
    15301 atggagctgc aggtgcggga taatggagtg ggaattccga aagagagcgt aggccggatt
    15361 ttcgagaggt tttaccgggt ggataagggc cgcagccgca aacagggcgg cacaggcctt
    15421 ggactttcca ttgtaaagca tgttgtgaac ttctatcacg ggacggtaag cgtttcctcc
    15481 agccaggagg agggagatcg cggaagtatc tttaccgtgc ggctgcccat cgccagagag
    15541 gcgaagcagg acagccgcgt ctgataacag aaggggagtt tgagactatt caaacagaga
    15601 atttctgctg tacgctttga gaatccgttc tcgggattcc tcctcggctt ccgtttcctt
    15661 tttttcgttc tgcttctgag aaggagtctg ctgagagacc gcgcccttaa atacagggtt
    15721 gatggccttt aaagcaggct cttttttgtc gagcgcagag acgaacagga attttctgat
    15781 gcagaacaga atggccactg agagcatgca cagaagattg tctaccatgg aggtgtgttc
    15841 aatgatgacc tgtctggcca ctgcgaaaag aagcacctct accacagagt ccagatcgtg
    15901 gcggcagaac atttttaaaa gctcgattcc gattacgatg ttgaacatga aagtcagaaa
    15961 agtgatgaaa gctcctgtat ccgccagaag cagaatctgc ctgggaacgc ctaaaaaagt
    16021 aatgatgagg ccgatgatga tacagacggc ggcaatcacc tcgaaataaa aggccgtacc
    16081 gaaaatcaga agctgagccc gggcgagagg gccttccagg acctgtttga ctttgggttt
    16141 cataaaagaa aaaacctcct ttactgataa aaactggtta ttatgtatat aataagatga
    16201 ttatagggga aaattgaaag aaattcaaac aaaaagaaga ttgttgttaa aaaaatgcaa
    16261 agaaagatgg gcggagagga aggaaaggaa gcagaagaaa aaatgcacaa tttccgtcct
    16321 tattttttgt gcaatctaac gattttttcg ctttaacgcg ttgatttcgt gggatattaa
    16381 agaaatgaaa ttgacgaggg ggaaaaagtg tagtaagatg gcgttaataa aaatttaacg
    16441 cctaattcat tcagggcgtt aaaacaggaa aaaggataca tcggaggagt aaaaaatgaa
    16501 aaagacagga aaaattgcag cggcagcaat ggcaggagtc atggctcttt ctatggcagg
    16561 ctgttcagga aacgcagatt cacagacaga agcagcaaag acagaggctg agagcgcgca
    16621 ggcagaggac acatcgaaag aagctgacgc ttccggcgat tcctataaaa tcggcgtgct
    16681 gcagctgact cagcacacgg ctcttgacaa ggtaaacgaa ggctttgtgg cggcaattga
    16741 ggagtcaggc attgacgctg agcttgatca gcagaatgct tccggcgatc agtcggcctg
    16801 ccagaccatc gcgcagatgc tggtagacag tgagagcgat ttgattttcg ccattgccac
    16861 tccggcagcc caggctgtgg caggcatgac agaggagatt ccgattgtag tgagcgcggt
    16921 gacggatccc gctgactccg gactggtaga ttccaacgag aaaccgggac gcaacgtgac
    16981 gggaacgtct gatttgactc ctgtaaaggc tcagatggat ctgcttcaga agctccttcc
    17041 ggatgctgag aaggtgggaa ttctctacag tacagccgaa gcgaactctg aaattcaggt
    17101 agagatggca aaggaggctc tggaggacgc tggcattcag tatgaggagt acacggtttc
    17161 caatacaaac gagattcaga cggttgtgga gtccatggtg ggaaatgtag acgttatcta
    17221 tactcctact gataacacga ttgcttccgg ctacgctaca gttgccatgg ttgccacaga
    17281 aaacaagatt ccgaccatct gcggagagag cggacaggta gacgagggcg gtctcgtaac
    17341 ctatggagta gattactatg agttaggccg catggcagga gagcaggcgg ttgagattct
    17401 cacagaggga gcggatatcg cttccatgcc aatcggatac atgaaggacg ctgactgtga
    17461 gcttcagatc aacgaagata cagcggcggc tttaggactt gatatgtcag tgctggagga
    17521 agaataatgg caggaatact ttcctccctt cagggcgccg taggacaggg cgtgctttgg
    17581 gggattatgg tgcttggtat ttacattacc ttccgtctga tggacatcgc agatttgacg
    17641 gtggacggaa gcttcgcttt gggcggcagc gtctgcgcgg cgctggtagc cggcaagggc
    17701 atgaatcccg tgctggccct cgtggtctgt ctggcagcgg gcatggcggc cggagcagtg
    17761 acgggaattc ttcacacagt atttgagatt ccggccatcc tggcaggaat tctgactcag
    17821 atttccctct ggtccattaa cctgaaggta atgggcaaga gcaatatgaa cctgggaaag
    17881 gcggagacgc cgatttcctg gctgaaggac agcttcggac tgactcagaa tcaggccatg
    17941 attgtcacag gacttgtagt aacggtcctt gtgattgtat ttctctactg gttctttgga
    18001 accgagcttg gaagcgccat gcgcgccact ggaaacaacg aggacatgat ccgcgctctg
    18061 ggcggaaata ccaaccgcat taagctgctg gctctgatgc tcagcaacgg tctggtaggc
    18121 ctttccggcg gcctggtatg ccagggacag aattacgctg atattcagat gggaacagga
    18181 gctatcgtaa tcggcctggc ggccattatc atcggcgagg tgctgatggg gcgtctgatc
    18241 cccttctact ggaagctgat tgctgtggtg gcaggctctg tgatttacca gattatccgc
    18301 gccgttgtgc tgagactggg ctttgactca gacaatatga agcttttgac ggcagtgatc
    18361 gtggtaattg ccctggctgt gccggttatg gctaccagat acaaacagaa aatggcgtac
    18421 acggaaggag gggaggagta atgctgacga tttccaatgt gaagaagacc ttcaataagg
    18481 gaaccatcaa tgagaagaag gcgttaaacg gcattgacct ccatctggac gagggagatt
    18541 tctgcaccat tatcggcgga aacggagccg gaaaatctac gatgctgaat atgatcgcag
    18601 gggtgtaccc cattgactgc ggaaagattg tgattgacgg cgtaaatatt tccagggagc
    18661 cggagttcaa gagggccaaa tatatcggcc gggtattcca ggatccgatg cgtggaacgg
    18721 cggccaatat ggagattcag gaaaacctgg cgctggccta tagaagaggc cagagaagag
    18781 gcctgggctg gggcattaaa aaccaggaaa aggagcgcta cagggagctg ctcactcagc
    18841 tggatctggg attagaggat cggatgacca gcaaggtggg acttctctca ggaggacaga
    18901 gacaggcgct gacgcttctc atggccacgc ttcagaagcc gaagctgctt ctcttagatg
    18961 aacatacggc ggcgctggat ccgaaaacag cctccaaggt gttaagcctg acagagcgga
    19021 ttgtggaaag ccagaacctg acggccatga tggtcactca caacatgaac gacgcaatcc
    19081 atatcggaaa ccgcctgatc atgatgcatg agggacgcat tatttacaat gtggcaggtg
    19141 aggagaaaaa gaatctgaag gtagaggatc tgctccgcaa atttgaacag gccagcggcg
    19201 gacagtttgc caacgacaga atgatgctgg caagataaca gaataagcga tggagaaagg
    19261 ggcagaggca attctgtccc ttttcatttt attttttctc tattggcatt ttttctgatt
    19321 aatgctataa tcatacccaa cgaattgccc agttggcagt gaatgaaaaa cagcgtcagc
    19381 acaaagcggg aacatgcctc tgtgtgctgg ccctgaatca gatggaataa gcggagaaaa
    19441 ctgaatgaaa gaaaaacagg atttagaaca tgtagatggg ctggatacag aggatttgga
    19501 gctggttgat ttagacctgg aagatctgga tcagctgccg gacgagcctg ttcagcagcc
    19561 agaagagaac ttagaacatc aggcggaaga cgggaaggca gagaaggatg aaccacctaa
    19621 aaagcgcaga aagcggaagg ggttctataa ggaatacgct gtgattggcg tattggctct
    19681 ggcgcttctt gcggtggtga tttttgcagg gagccgtttg ttcggaaaaa aagacgatcc
    19741 ggctttaaat gcaaagggaa aggctgtgga ggaaacagtg tccaaagagc aggaaaaggc
    19801 cgcgaaggaa gaggaagaaa agaaggcagt tgtagattct tacaagaatc tgggcatcgt
    19861 ggaggtgaca ggctacctga acgtccgcga gacggccagc cctgacgcag atgtgatagg
    19921 aaagctccag gacggaggag cctgcgagat tcttgatgat tccacagagg agtggtatca
    19981 tatttcttcc ggcggaatcg agggctatat cagcgcagag tacgttctga caggtgaaaa
    20041 ggccagagaa aaagcgatgg aagaggctgc tctcagagcg actatcacag cggattcctt
    20101 aaatatccgc aaagagccag gcacctctgc cgaggtagtg ggacaggcct taaagggcga
    20161 gcgctatttg gtgaagagcc aggaggacgg ctggattcag atctcttccg gctatatttc
    20221 cgacgattac gccacagtag cctacggcct caacgaggcc agaaagttgg atatgcgatc
    20281 catggtttta aatctctatg acaatctggg tatttccagc gtggacagct atctgaatat
    20341 tcgaagcgaa ccccgcgagg acggcgacat tattggaaag atgaccagta aatcggcagg
    20401 agaaattctg gaaaccagcg aagatggaaa atggtacaaa attaagtcag gccctgtgac
    20461 cggttatgtc agtgcagatt acattctcac aggccaggca gccaaggacg aggccctgca
    20521 ggtagcggag ctgatggcca ttgtatccac agaccgtctg aacgccaggg aacagccgac
    20581 tcaggattcc aagatctgga cgcagatctc caataatgag agatatcctg tcacggaaca
    20641 gctggacggc tgggtaggga ttgagctgga tacctccacc gcctatgtgt ccacagatta
    20701 tgtggatgtg cggtatgccc tcccggaggc ggttaagttc agtccgctgg atggaaacca
    20761 gtctctgaga aataaaatgg tcaactatgg tctccagttt gtaggaaacc ggtatgtatg
    20821 gggcggcaac gatccccaca caggagcgga ctgctccggt tttgtcaaat atgtttacag
    20881 ccatgtggca ggaattaccc tgcccagaac ctccagagag caggccagac agggaactcc
    20941 gatcaaatct tcccagatgc ggccgggcga tctgattttc tatgcaaacg gcggaggcac
    21001 agtcaaccat gtggccatgt acattggaaa cggacagatt gtccatgcgg ccagccgcag
    21061 aagcggaatc aagatttcca cctggaatta cagaacgccg taccgcattg taaatatgct
    21121 gggagattaa gacggcggtc tgagagaact gcgtgttcat aataatttaa cttttttcca
    21181 gtcgatttta tcgacaaaat gtgctataat ccgctgtgta tgtttagaca gagcagcgcc
    21241 gccggacaga gcgtcaggcg tttttggctg acggcgctgg agaaattaca gtaaatggag
    21301 cgatgaaaat gggaattaat aaaccagacg attacgcagc cagacttctg aaggccagga
    21361 agaggagaaa tggaaaggat cctcttaaat atttcctgat tgcggcggga tgcgtgattg
    21421 tgattctcgt cattgtactg gcgggaaagc ttgcaaaggg cggcagaatc gacctgggcg
    21481 cgggcagaac tggaaaaggc cccgaaatag agggtgtatt cgagagcgaa ggaagcacag
    21541 aggcagcgca gggcgatttg atggatgaag acgaagagct gagaaagatt gacgagcaga
    21601 aggcagctgt cgtagagtcc tatgagaatc tgggaatcgt gcaggtaacc ggttatctga
    21661 atatgagaga gagcccggat cagaacgccg atattatcgg aaagatgcta aacggaagcg
    21721 cctgtgagat tttagacgac tctcaggagg gctggtatca ggtgacctcc ggcggcctga
    21781 ccggttacat cagctccgag tacgtgctga caggcgacga ggccaagacg gcggcctttg
    21841 atctggtaga tcagatggcg gttatcacag ccgataagct gaatgtgaga agcgagccca
    21901 atcaggacgc tcaggtgctg gagcaggtgc tgagaaacga gcgctatacc attgaggaag
    21961 aggaaggcga ctggatcaag attccggacg gctacatttc ttctgagtac gtgcaggagc
    22021 gctacgcgct gaacgaggcc agaaagctgg atctgcgcac catggttctg aatatgtatg
    22081 acaacattgg tatttccaat gtaaacaatt atctgaacat ccgcaaggag ccgaaggaag
    22141 acggaaagat tatcggaaag atgaccagca agtctgccgg tgaaattctg gagacgacgg
    22201 aagatggaaa gtggtataag attaagtcag gtcctgtgac tggctatgta agctccgagt
    22261 acattctgac tggccaggcc gccaaggacg aggcgcttca ggaggccaag ctgatggcca
    22321 ttgtatccac agatcgtctg aatgccagaa cagagccgaa cacagaggcg ccgatctgga
    22381 ctcagatttc caacagcgag cgctacaacg tactgagcca gcaggacggc tgggtagaga
    22441 ttgagctgga tactacctcc gcctatgtgg ctaccgatta tgtggatgtc cgctatgcgc
    22501 tgaacgaagc cattgagttt actccggtgg aggagacttc tgatacagga agctctggcg
    22561 gaaagggagg ttcaggcgga aaaggcagct ccggcagcaa gggaagctct ggaagcggat
    22621 cctccaagcg ttcccagatt gcaagctatg cgactcagtt cctgggcaat ccttatgtat
    22681 ggggaggcac cagccttaca aacggcgcgg actgctccgg atttaccatg gctgttatgt
    22741 ctcacttcgg cgtcagcctg ccgcaccatt ccggttccca ggccaatgcg ggaagagcgg
    22801 tttcttcctc cgagatgaga cctggcgatc tggtattcta caccaacagc ggcggcacga
    22861 tcaaccatgt ggctctctat attggaaacg gccaggttgt acacgcctcc aacccaagca
    22921 gcggaattaa gatttcccgg tggaattacc gtactccggc aaagattgtc aatgttttgg
    22981 gagattagaa gagagttgta aagatagtat aaaaagcaga taagatttcc ttgctccact
    23041 gaaagtcgct ggaaagctta tctgcttttt taaattttct ttaggcgggg cagtcaccgg
    23101 aaaataattc tgcttctttt tgatatgttt ttacagtgga ggaaccgctg ggagtcttat
    23161 ctgcttttct gcctctaata gtgtatgacc tgaggggagt cctgaatggc ctggacgact
    23221 ggggctgctt cttctgaggt gaagtagcgg taggtagttt ccggaaccag agaacgtatc
    23281 tcctccaggc ggccgtcatg gatcagactc ctgaccaggg aggcgctgac agtatgtcct
    23341 tcctgttcca ggcggggaat gacggttaca gaagggccgc ctcctgcttc agcctcacta
    23401 atcatgacct gattgtagag ccctgtcacc tggctgaagg gttcctctcc gacaaagcgg
    23461 acagagacag acagggcttt cgcaatactc tgaaacaggc gcacgtccaa ccgggcatgg
    23521 gaacagatag cactgtcctc gtccttcaga aagtaggagg ggaacgtggc gttggagatc
    23581 agatagcttc ctgttttgtg gagaaccaca ttggaaagat gggaaattcc ctgttttacc
    23641 agctgaaagc ggactgggaa aggaaccagg gacgcgtcct ccgagacgac gaacaggtgg
    23701 agaaggctgc aggcagaggc agctttttca agcagatact gatgtcccag agtaaaggga
    23761 ttggcgttca tgacaactgc ccccacagga agtccgctgc gggaaggaac agccccgctt
    23821 tcgtcggtct cctgaaccag ccgctttaaa tagtctgcaa agccgctctt cttattttcc
    23881 ataaacaccg cttctccatc agagcgggca atttcgtaga atcccagatc cttaaaaaac
    23941 atggccttgc tgcatttggt gtagaggaac agatggaaat ttccgcgccc gtactggtat
    24001 tctgtcagat gggagatcag ctgccccagc agtccctcgc cctgaaaatc agagtccact
    24061 gccatacacc gcagggtatt tccaaagcag gaaccagtgg ctgccaatcg gtaattttca
    24121 tcgtaaagac cgacagtgta atcaagattt ttgtctcttc gtatgccctc cttttctaac
    24181 aggctgttta cttgatccat tccgcgtctg tccgttggaa ggatttcgct gatgcggtat
    24241 tctgacatgg ctcttagacg tctcctttca ttctggcgtt ttctttcatt ataagtcaaa
    24301 tgtttagaaa aatcgaatat aaaaatccct atatcttcca taagaataaa tgatgtatga
    24361 acggcttttc acggggaagg ataagaaaga gaaagccggc tgcacgaaaa cgccgggaag
    24421 caggaaagaa aacgtaaaac ggaggaaggc catgagggag ctgtacgaag aaaagacagg
    24481 atatgtaaga gaaaaccaca ggggcgatga taaaacagag aactctgaga aaacagaaag
    24541 cgctcagaat agttcgcagc cgcagactgg agaaaaaggg gaggaaagcg cccggacgga
    24601 ggaaaggatt cgggagacgg gacaggttct tttggacagc ggaagacaga aaaacagaat
    24661 ccacctgctt tccgtgattg gcgagatcga aggccatgag aatctatcgg gaagtacgaa
    24721 aaccacgaaa tatgaacata tcctgccgga gctggccaag ctggaggacg acgatgaggt
    24781 ggacggaatg ctgattctca tcaacactgt aggaggggac gtgagctgcg gtcttgccct
    24841 ggcggagatg attgcttctc tcagccgtcc taccgtgtcc cttgtcatag gggacagcca
    24901 ttccatcgga gtccctctgg cggtggcgtc cgactactcc ttcattgttc ctacagggac
    24961 catgatgatc cacccggtac ggatgacagg aatggtcatc ggagcagtcc agacctacga
    25021 ctattttgag atgatccagg acaggatttt aagcttcgtg gcaggacacg cccaaatcgc
    25081 gtacgatcag ctgaaacgtc tgatgttgaa tacagaaatg ctcaccaagg atttggggac
    25141 aatactggtg ggccaggagg cggtgaagga gggcttgatt gaccaggtgg gaggaatcag
    25201 ggaagcgttg aaaaaattga atgaattaat cgaaaaaaag aaaaaacttt aatgcgttgc
    25261 aatttcctct aaatttatgt atacttatct gatgagtaaa aaaatctgga ggcttagata
    25321 agtggcaggt acaagcagga aaaaacagga gacatcagaa ggtccgagat cgcgagcaaa
    25381 gaacagcaga agcaagggag cgtcctccgg aaagaaagga acgtcttcca aaacagatag
    25441 aaaaacggga aaaagcgccg gaaaggctga tacaaaggcc agaggaagca gcaggcgcag
    25501 ggatccggag ccggaggaaa acagttttat tttaacagaa gtggcgatta ttgcagtgtt
    25561 tgcattgtcg gtgcttctgt ttttgagcaa ttttcatctg tgcggcgtgg tgggcgattt
    25621 ctgccgggaa gccatgcttg gaaccttcgg aaagctggga tatctgttcc cggttctttt
    25681 atgtgtagga agctgcttct atttatcaaa caggggaaac agaagggcgg ttatgaagct
    25741 ggcggcgtct gcagtgacgc ttctggcgct gtgcggcctg gcccagctga ttttcggagg
    25801 aggctacagc gaggagctga agcttttcga ttactttaag caggacgccg tttccggaaa
    25861 aggcggcgga atagtgggag gcgttctggt gacggttctc tgttccacag tgggaaccat
    25921 tggcgcgtat ctgatcctgc tggttctttt tgccatcgga gtggtgtgca ttacagaaaa
    25981 atccctggta ggagctgtca ggagaggcag cgggcgggca taccgttatg cgaaggacga
    26041 tatgaaccgc agacgtgaaa tttacgagga gagacgggaa gagagaagag aagaacgcca
    26101 gcgcatcagg gaggagagag ccagaggcat tgacatggat gccgcgacgc tgggagaata
    26161 ttcctatgag gattcttatg acaattccgg cgaggattta tatgaagatt cccgaagaaa
    26221 ttcccgtgga agatacagag aagacgccat agaaaacgac cggtatgaca gcccggagga
    26281 ctacgttctg gagcctgaga gtaaggagcc tctgaacccg gctgacattt tccgcggaag
    26341 cattattatg ccaggccgcg gggagcagga agaactggca gaggagccgg tagaacgcct
    26401 ggaggagtgc agggctgaaa aggccgaaag acatacagga ggcatccatg catttgcaga
    26461 acagaaggcg tcccgctcag aagcggagcc ggagcatcca ggcgcagcag aggaagcggt
    26521 acataaagag gaacgccggg aagcactgaa ggaaaatcag atcggaaccc agccggcaga
    26581 gcatgacagg gtgtttgtca gccgcagaaa gggttctgcc cattcggaga cactgcgcag
    26641 ggcagagatg ccggaatttc tgcctgagac agaggagctg gagccgatgc aggacagcgg
    26701 cttcgagact ccggccaggg aggagactct gttaaaaagc atctatgcag agagagacac
    26761 gagaaccttt gcagagcttc ggatggagga accgtcggaa gacagcggat ttggaattga
    26821 aaatcaggaa gaggaaatct attatgagcc tattgacgct gacgaggctc tggcagaaga
    26881 gaagtcccag actggcggca gcccggcaga agctgatggg gatttcgata cagaggatct
    26941 ggctggaaga gacgctttaa cagctgtaaa ggagcagatc cgggaagccg gagagagggc
    27001 catggccgca tccgatcttt cctgggagga gggtaatcag atcgtgactg cctccggaaa
    27061 ggtcatggag acagacgcag atctgatgcg gaaaactctt gagagaaagc gccatgagac
    27121 gaaagcagcc tcttccgatg aagagagaga gcatggaaac agggagtctg gaagaagcct
    27181 tggcagagag cagacagacc gttctgcagc cgcagccgtt tcaccgcatc cactgtcagg
    27241 aagacaggag acagagagaa gacaggaacc ggttaaaaag ccgcagcctg agaaaaagcc
    27301 ctatgttttc ccgccgatgg atctcctgaa aaagggaaga gctgtgggag gacgttccga
    27361 gcaggaatac aaggacacag cgattaagct gcagcagaca ttgaagaact tcggagtggg
    27421 cgttacagtc accaacatca gctgcggccc ggctgtcacc cgatatgagc ttcatccgga
    27481 gcagggcgtc aaggtcagca agatcgtatc cctgtccgac gatatcaagc tgaatttagc
    27541 tgctgctgat atcagaattg aggctccaat tccaggaaag gccgctgtgg gaatcgaggt
    27601 tcccaataag gagacggaga ctgtgcttct cagggatctg ttagagtcag agaactttaa
    27661 gcgggcctcc tccaagctgt cctttgcagt gggaaaagac attgcgggac agaccgttgt
    27721 gacggatatt gcgaaaatgc ctcatctgct gattgcggga gctaccggtt ccggtaagtc
    27781 cgtgtgcatt aacacgctga ttatgagcat tatttataaa tcctctccag aggacgtaaa
    27841 gcttatcatg atcgatccga aggtggtgga gctgagcgtt tacaatggaa tcccgcacct
    27901 tctgattccg gttgtaaccg atccgaagaa ggcgtccggc gctctcaact gggcggtggc
    27961 ggagatgacg gagcggtatc agaaatttgc caagtacaat gtcagagatt taaagggcta
    28021 caatgaaaag atcaagctca tagaggatat tgaggatgag aacaagccga aaaagctgcc
    28081 gcagattatt attatcgtgg acgagctggc agaccttatg atggtggctc caggcgaggt
    28141 ggaggacgcc atctgccgtc tggcccagct ggccagagca gccggcattc acctggtaat
    28201 cgcgacacag agaccgtcgg ttaatgttat tacaggactg atcaaggcga acattccgtc
    28261 cagaatcgcc ttctctgtat cctccggcgt ggattccaga acgattatcg acatgaacgg
    28321 ggcagagaag ctgctgggca agggcgatat gctgttttac ccacagggaa tccagaaacc
    28381 gcagcgtgtg cagggagcgt tcgtttccga tcaggaagtg tccagagttg tggaattttt
    28441 ggcagaggag ggcctgacta cagagtacga tccggaggtg gagaagaaga tgacttcctc
    28501 tttctccggc gcagggcctg acagcgcagg cgacagagac gcctactttg aacaggcggc
    28561 ccggtttatt attgaaaagg acaaggcttc tatcggaatg cttcagagaa tgctcaagat
    28621 cggctttaac agggcggccc gcattatgga tcagctggcg gaagccggcg tagtaggcga
    28681 ggacgagggc actaagccga gaaaggttct catgagcgag gagcagttcg aggaactgat
    28741 ggaacagggc tattaagata cagagccggg gaaaaaagcg gcagagacac gtaccctgca
    28801 gggcgttccc gcgtatgata aaaagggagg aagaacaatg ctgaatgact ggttaaagga
    28861 gcttaaatat gagcttgtgc agggagaact ggaaattcct gtaaaggaag tcgtttacga
    28921 ctccagaaag gccggggagg agaccgtgtt tgtgtgcatg aagggcacca atgtagattc
    28981 ccacgatttt atccccacag tgttagcggc gggaacgaag gcgctggtgg tggagcggga
    29041 ggttcccggc atcccggagg acatgacggt tctcaaggta gaaaacggcc ggaacgccct
    29101 ggctcttctg tctgcggccc gcttcggata tccggcagaa aagatggtga ctatcggcgt
    29161 gacgggaacc aagggaaaaa ccactaccac ttacatgatc aaatccatcc tggaggcctg
    29221 cggaaagaag gtaggcttaa tcgggacaaa cggagcggtg atcggagata agcattacgc
    29281 cacaaagaac acaacgccgg aatcctatat tctggagcag tatttcgacg agatggtgaa
    29341 ggccggatgc gagtacatgg taatggaggt atcctcccag agctacctga tgcaccgggt
    29401 ggacggcctg acctttgact atggcctgtt tttaaatatt tcaaacgacc atatcggccc
    29461 gggagagcac gagagctttg aggaatatct gtactataaa aagcagcttt taaagcactg
    29521 caaaacggca atcgtaaacg aggacgacga gcatttcgac gagattgtaa agggagcgcc
    29581 gtccaagatt tacaccttct ctctggagcg tccggccgat tttgaggcgt ccggcatccg
    29641 atacgtgacg gccagcgact ttgtgggact ggtattccag atgatgggca gttacgagct
    29701 ggaggtcaag gtgaacgtgc cgggacgctt caacgccgcc aacgccctgg ccgctgtggc
    29761 agtgtgcagc ttctttgatc tgccgaagcc caaggtatcc cacggtttag agaacctgaa
    29821 aattgacgga cggatggaga ttgcctataa atcctccagg atgacagtga tcgtagacta
    29881 tgcccacaat gcagtgagta tggaaagcct gctgagaacg ctgagagatt ataagccgaa
    29941 acgcctggta tgcgtatttg gctgcggcgg caaccgggcc aaggagagac gctattctat
    30001 gggagaaata ggcggaaaac tggctgattt ttgcattatc acggaggaca attcccgcta
    30061 tgaggacgtg caggagattc tcacagatat caaggtgggg ctttccatga ccagcggaac
    30121 ctacattgag attcctgatc ggaggaaggc cattgaattt gctgtttccc atgccagaga
    30181 gggagatatg attgccatta tcggcaaggg acacgaggac tatcaggaaa tcaaaggcgt
    30241 gcgctatcct ttcctggacc gccaggtggt gcaggagacg gtggagaagc tgggactgta
    30301 gaagcggcag gctcaggctt cagacagaat gtatgggaag gcagaggacg aaaacgatgg
    30361 aacacataac tgtaaaagag attacagagg cggcaggcgg ccgtctgctg gcaggagatc
    30421 cgtctgctct ggtgacagag atcagcattg attccagaga ggcgggaaaa ggatgcctgt
    30481 ttgtgccgct gatcggcgaa aaaaacgacg cccaccggtt tattatgaca gccctggctc
    30541 agggaacagc ggcagtattt acctctgagc atgaggagac ttcagaggaa gtggaggagt
    30601 ccagacagag atggccagag gccgcctgga ttcaggtgga ggatacgaga aaggccctcc
    30661 aggctctggg agccttcatc agaagaaggc tgacgcttcc tctggtaggc atcacgggaa
    30721 gcgtgggaaa aacgaccacc agggagatgg tggccgcagc tctttctgcc ggatacagag
    30781 tgtttaagac gccagccaat cacaacagcc agatcggcgt gcccctgact ttgtctaaga
    30841 tttccgggga ggatcagatc ggcgtgctgg agctgggcat gagcgagccg ggagagatgg
    30901 aggtcatcgc ggagattgcg gctgtggaca tggctgtgat tacaaacgtt ggcgtcaccc
    30961 acatcgaaaa tcttggatcc agagaaaata ttttaaggga aaaattaaat attcagcggg
    31021 gaatgaaccc gtcaggcccg attttcctga acagcgacaa tgatctgctc tgccgtgtgt
    31081 ccggctggga cggacgggag acggtttatt tcggaacagg ggagcaggcc gactacagag
    31141 cggcagatat ttccatggaa aacggctgtc cttcctttac catggtacat ggagacgtga
    31201 gaattcccgt tacgctgtct gtgatgggag aacacaacat tctaaacgct ctggccgctc
    31261 tggcggtggc ggatcgaaac ggcgtttctc tggaagcggc tgcagaaaag ctcagggaat
    31321 tcggaggctt taagaaccgt cagcaggtct atgaggcggc aggcgttacc atcattgacg
    31381 acacctacaa tgccagcccg gattccatga aggcgggcat taaggtgctg tcttcctttg
    31441 aaacgagcag gaggagagtg gcggttctgg ccgatatgaa ggagctgggc ccggacgccg
    31501 ggctgtttca ccgtcaggtg ggagaatttc tggcaggaga gcaggtggat gctctcatca
    31561 ctctgggaga gctggcagag cagattgaag agggcgcccg tttaaggcgg ccgtcccttt
    31621 ttgcggcttc cttcagagac aaggaagaga tgacccggtt cctggaagag ttcctgaagc
    31681 cgggagactg cgtcctgttc aagggatcca acagcatgaa gctgggggag actgcgctct
    31741 atttcagaaa caaggggaag gagcaggcag agtccgccca ggcgagaggc tgacagaacg
    31801 tatgaagcag acctttgcaa atgtaattat tgatatttcc catgaaaaag tggatcgcac
    31861 ctttcagtat atcgtgcctg agccattaaa ggacaagatc agggcgggcg ttcaggtgga
    31921 gatccccttt ggaaagggaa attccctccg ccgtggcttt gtggtggagg tgactgaaaa
    31981 gccggaattt gatattgaca gaatgaagga gatagctggg atttcacctg accgtgtgtc
    32041 ggtgcagtcc cagcttattg agcttgcctg ggaaatgaag cgcatctatg gttccaccat
    32101 gaaccaggcc ttaaaaacgg tgcttccggt aaagcagaag atgaagcgca gggagaagaa
    32161 gaccgtccgc tgccgcctga ccagagagga gcttgcagag gccctgaaag aagccagaag
    32221 aagaagctac cgggccagaa tcagactgtt cgaggccttt cttgagacgg aacagattcc
    32281 cggggaggtg gtggagcacc agttaaatat tacggctgcc tccttaaagc ccctggttga
    32341 aagcggggca gtggaggtgg cgcgaaggga ggtataccgg gatccgctga aaggccttca
    32401 gaaggaggcc gcccaggtga agctgaacgc cgatcagcag gctgcggcag ataccttctg
    32461 ggactcctat aaggaacgcc tgatccaggg gccggaggga caaaagaggc tgtccaggga
    32521 caggacctgg cttctccacg gcatcacggg aagcggcaag acagaggtct acatggaaat
    32581 gatggatcgt gttctgaggg agggccgcca ggtgattgtg ctgattccgg aaatcgccct
    32641 gacatatcag acagtcatgc ggttttataa gcggttcggc ggcaggattg ccattttaaa
    32701 ttccaggctc tcggcgggag agcggtatga tcagtgggaa ctggccatga agggtggggt
    32761 ggacattatg attgggccca gatcagccct ctttgcgcct ttttccaatc tggggctgat
    32821 agtcattgac gaggagcacg agggggctta caaaagcgag accatgcccc ggtaccatgc
    32881 cagggaggcg gcggggatca gagccaggct gtcgggagcg gatgtggtgc tgggttctgc
    32941 caccccttct atggaatcct acagcagagc cctgtccgga gaatatgggc ttctgcgcct
    33001 tcagaaaagg gcctcctcag acagccgcct ggcccaggcg gaagtggtgg atttgagaga
    33061 ggagctgaaa gcaggcaata aaaccatgtt cagccgcagc ttgtcggaac agatacagga
    33121 caggctgagc cgcgggcagc agattatgct gtttatgaac agaagaggct acgcaagctt
    33181 tgtgtcctgc cgttcctgcg gggaggcggt tcagtgtccc cactgcgacg tgtccatgac
    33241 gctccacaaa aacggccgcc tgtactgtca ctactgcggc tattctctgc ccatgccgaa
    33301 gctttgcccc tcctgcggct ccccctatat cgcaggcttt gggaccggca cccagaagct
    33361 ggaggagatg acaaaacagc tgtttcccca ggccagagtg ctccggatgg acgcggatac
    33421 caccgctaaa aagggaggac atgaggaaat cctctctgcc tttgaggccg gggaggcgga
    33481 tattctcatc ggaacccaga tgattgtgaa ggggcatgat tttaaaaatg tgacgctggt
    33541 ggggattatg gcggcggatc tctccctgaa tacgccggat taccggtgtg cggagagaac
    33601 gtttcagctt ttgactcagg cagccgggcg ggccggaaga ggcagccagc cgggcagtgt
    33661 agtgattcag acctacaggc cggatcacta cagcatcgag acggcggcca gacaggatta
    33721 cgaggccttc tacagccggg agatcgccta cagaagaatg atgaactacc ctccggcctg
    33781 ccggatgtcc gccgtgctgt tcgcggcgaa ggacgaggcg gcgctggagc agttctgccg
    33841 gaaggcttcg gagcggattt ccatgattct taaggggctt tccgggccct gccagtctat
    33901 cggaccggtc aacgcgcctg tctacaaagt taatgatatg tatagaaaaa ttttatatat
    33961 taagtgtgaa aattgtgata tactagataa aatcagggac agtatggatt tcctgacaga
    34021 aagcggcgcg ggaaccgtcc aggttcagta cgacgtgtcg taagcgcaga agaaataggc
    34081 tgtaaacagc agaatacaga aaataacaga acataaaagg agaggattca gatatggcaa
    34141 tcagagaaat cagaaccatt ggagacgagg ttctcagaaa agagtgcaag ctggtgaagg
    34201 agatgactcc ccgcacggca gagctgatag aagatatgtt tgacaccatg taccaggcca
    34261 acggagtggg gctggcggct ccccaggtag gcgtccgcaa gcagattgtg gtcatcgacg
    34321 tggaggacgg aaatcaatat gtgctgatta atccggaaat tctggagacc agcggaagcc
    34381 agacaggccc ggagggctgc ctgagcgtgc ctggaaaatc aggaactgta acccgcccgg
    34441 atcatgtgaa ggtaaaggct ttaaatgaga acatggagga gtacgttctg gagggcgagg
    34501 gcctgcttgc cagggcaatc tgccacgagt gcgatcactt aagcggcgtt ttatacgtgg
    34561 ataaggttga gggagagctg gaggacgtaa gcgcagagtt cgaggaagag tagaagaacg
    34621 tccgcagagc agaaagggga tgcacacatg aagttagtat atatgggaac gccggatttt
    34681 gcagttcctg cccttgtttc cctggtggag gcaggccatg aggtggcggc ggttgtgact
    34741 cagccggata agccgaaggg acgggggaaa gccgttctta tgactcctgt aaaggagaag
    34801 gctctgtcct acgggattcc tgtttatcag ccggcccgcg tcaagaagaa tgaggaattt
    34861 ttaaacgttt taaaagagat tcagccggac gctatcgtgg tagcggcatt tggccagatt
    34921 cttcccagag agattttaga gcttcccaaa tacggatgcg taaatattca cgcctccctg
    34981 cttcccaagt acagaggagc ggctccgatt cagtgggctg tcatcgacgg ggagaaggag
    35041 agcggtatta ctaccatgat gatggatgtg ggacttgaca ccggagatat gctggagcgg
    35101 gtggttgtcc cgctggcaga ggacgagacg gggggaagcc tgtttgacaa gctttccatg
    35161 gccggaggac cgctgattct ggagaccctt gagaaactgg aaaacggaac tgccgtcagg
    35221 acgcctcagc cggaggcagg cgttacctat gcggggatgc ttgacaagtc tctgggcaat
    35281 atcgactgga cgaaaggcgc ggcagagctg gaacgcctga tccggggcct gaatccatgg
    35341 cccagcgcct acacccacta cggtgagaag accatgaagc tgtgggcggc cgacgttctg
    35401 ccggagaatt ttgaaggtga accaggccag attgtaaagg ttttaaagga tcgctttctg
    35461 gtaaagacgg gagacggaac cttagctgtg aaggagctgc agctggaagg aaagaagcgc
    35521 atggatgcag gcgccttctt aagaggtttt tccttaaagg aaggggagaa gctggggctg
    35581 tagaggccag gcctgccgtg gccgcggctg gatccggctt tgaagcggga acgccatagg
    35641 gggagaatga gtgaaaaggg cggtcattta atttgagaaa ggaagtcttt tatctatgta
    35701 ctatggttat ggattttacc ccatgtttga tccgacgatg attctgatat taatcggagt
    35761 ggcgctttcc atggcggctt ccgccagggt gaacagtacc tttgcccgct attccaaagt
    35821 tcgttccatg acgggaatga caggggcgga ggcggctcag agactgttaa acagccaggg
    35881 tatctacgat gtgacggtgc ggcgcgtagg cggccgtctt tccgatcact atgatcccag
    35941 gagcaaaacg gtgaatctgt cagatgatgt gtataattct acctctgtgg cagcgatcgg
    36001 agtggctgcc cacgagtgcg gacatgcgat tcaggacgcg gtgggatacg cgccgttaaa
    36061 attcagagga gcgctggttc cggtggccaa ttttggttcc cagatttcct ggcccctgat
    36121 tctgattgga ttttttatcg gaggcttcgg ctctcccatg gtgcagctgg gcatcctgct
    36181 gttttccgcc gctgtgctgt ttcagctggt gacgcttcca gtggagctta acgcctcctc
    36241 aagagcggtg aagcttctgg atgctacggg cattctttcc ggcagcgagg tggacggcac
    36301 cagacgggtg ctgggagcgg cggcgctcac ttacgtggct gcggcagccg gatcgatttt
    36361 acagcttctg cgtctgatta tactgtttgg aggaagaaga gataatgact aaaaccggaa
    36421 gtggaaaacc ggcaaacgaa ggaaacagaa gcgcttcggg agcgcgggag attgtgctgg
    36481 acgttcttct tgagattctg gagaagaagc agtacagcca tctggtactc cagagagcgc
    36541 tcgcaaaata tcagtatctg gataagcagg aacgctcttt tatcaagagg accgttgacg
    36601 gtactctgga gcgcctgatg caggttgact gtctgattga atcatattcc agcgtaaagc
    36661 tgcgtaaaat gaagcctgtg atccgcacga ttctcagaat gagcgtctat cagatctgct
    36721 ttatggatcg gattcctgat tctgcagcct gcaacgaggc ggtgaagttg gcggtccgaa
    36781 gaggcttttc cggcttgaag ggttttgtga acggagtgct gagaaacgtg tccagacaca
    36841 aggatgagat cacatggccg gacgacagca cggcgttctg tctgccccag tggatttttt
    36901 ccatgtggga gaggcagtat gggaaagagg cggccagaac tatggcagag agttttctga
    36961 aggagagacc tctcactgtc cggatgaatt taagcctggc ttccagggag gagatcgctg
    37021 attctctgga aagccagggt gtgaaagtcc gggaaagcgg ctttgccgag gatgtggttt
    37081 tcttaagcca ggtagattac ctggagagcc tggacgcctt tttagacggc tggatccagg
    37141 tacaggattt aagctcctct ctggcgggag acgccgccgg agtgaaggag ggcgattacg
    37201 tcattgacgt ctgcggcgct ccaggaggaa aaagcctgca cattgcggag ctgcttcacg
    37261 gaaccggcat ggtggaggtc agagatctga ccgagaagaa aatcgctctg gtggaggaca
    37321 atatctggcg ttctggattt tccaatatcg aggccagagt gcaggacgcc acagaatttg
    37381 atccggacgc ccaggaaaag gcagatctgc tgattgcgga tctgccctgc tcgggccttg
    37441 ggatcatcgg ccgcaagcct gacatccgtt acaatgtgac agaggagcag acgagagagc
    37501 tggcgaagct gcagagagaa atcctctctg tagtctggcg gtatgtaaag ccaggaggga
    37561 ctatggtatt cagcacctgc acggtagatc cggcggaaaa tgaggagaac gtccgctgga
    37621 ttctgtcgca gctgcccttt gaaccggtgg atctgacaga cagaatagga gacgctctgg
    37681 cagagacact gttagaggac accaggaaaa agggatacgt tcagctgctg ccgggcttct
    37741 acccgggaga cggctttttt atctctgtat ttagaagaaa agaagagtag gatttaaaag
    37801 gaggctttaa gcatatggag agagacggac gggcagattt aaaatccatg acccttccgg
    37861 agctgacaga gtatctgaag gacttaggag aaaagccctt tcgggcaaag cagctgtatc
    37921 agtggatgca tgtgaagctg gcggcttctc tggatgagat gacgaatctg tccaaggaaa
    37981 tgagggggat tctgaaggag acggcttttt acgcgtcctt aaatccggtg gacgtgcgta
    38041 tttcccagat tgacggcacg agaaagtacc tgtttgagct ggaggatggg aatgtaatcg
    38101 agagcgtgct gatgcgctat aagcacggca actccgtctg catttcctcc caggtaggct
    38161 gccggatggg ctgccgtttc tgcgcctcca ctctggacgg cctggagaga aacttaaggc
    38221 cttccgagat gttagagcag atttaccgga ttcagaggga tatcggagaa agggtatcga
    38281 acgtggtggt gatgggttcc ggcgagccca tggacaatta cgacaatcta atccgcttta
    38341 tccatctgct gacagacgag aacggcttac atatcagcca gcggaacgtc acagtttcca
    38401 cctgcggcat tgttcccaga atccgccagt ttgcggagga aaatcttcag gtaactctgg
    38461 cgctttctct ccacgccccc aacgacgagg tgagaaaaac tctgatgccg gtggccaaca
    38521 gcttcgccct gaaggacgtg ctggacgcct gccattatta ctttgagaag acaggcagaa
    38581 gacttacctt tgagtacagc cttgtaaaag gagtcaacga taatctggac gaggccaggg
    38641 cgctggcgga tctgctgaaa ggccagcacg gccacgtgaa tctgattcct gtcaatccga
    38701 ttaaggagag agactttaaa cagtcggatc ggaaggctgt cgaggagttt aaacagtatc
    38761 tggaaaagcg gggaatcaat gtcaccgtgc gccgggaaat gggccgcgac attgacggag
    38821 cctgcggaca gcttcgaaaa agctatattg agaaggaaag gacgtaagga agatgaaagc
    38881 ctgtgctttg acggacatcg ggcgggtgcg gcctgtaaac caggactgcc gcttcgccac
    38941 gacagagcct atcggacctc tttcaaattt atttattgtt gcagacggta tgggcggcca
    39001 caaggccgga gaccgggcct ccaggcttct gatagagagc ctgacctcct acataaggaa
    39061 ctgttcgacc agaacgccgg tggaggcgct gaaccatgga attgcagagg ctaacaggga
    39121 aatctacgag gcttctctgg aacaccagga actggcaggc atgggaagca ctctggtggc
    39181 cgctacgata gaggattcga ctctctatgt agccaatgtg ggggacagcc gcctctacct
    39241 gattgagcgg gaaggaatcc ggcagattac cagagatcat tcttatgtgg aagagatggt
    39301 gtccctgggg cagattacca gagacagcct tgagtataaa aagcagaaga actatatcac
    39361 gagggcagtc ggcattgcaa agacagtgga ggcagacttt tttgaggtgg gcctgaagga
    39421 gggagactat gttcttctct gctcggatgg tctttccaat atggtggaca attccgccat
    39481 gttccgcctg gtgctgctgc caggccctct ggagagcaag gccagagcgc ttattgcgtt
    39541 agccaatcag aacgggggaa aggataatat agcagttgtt cttgtggatc cccagataag
    39601 tgaggtggac ggattatgat gcttagacca ggaatgtatt tgcagaatcg gtatgagatt
    39661 ctggatcaga taggctccgg cggaatgtca gaggtctacc gggcaaaatg ccataaatta
    39721 aaccgcctgg tggccatcaa ggtgctgaag gaggaattca gcacagacgc cgggtttgta
    39781 aagaaattta agctggaggc gcaggcggcc gcaggtcttt cccatccgaa tatcgtcagc
    39841 gtatacgacg ttgtggacga gggcagcatt cactatatcg tcatggagct gatagaggga
    39901 atcactctga agagctacat cacgaaaaag ggacggctga gctccaagga ggctatcggg
    39961 atcgccatcc aggtggctca gggaattgca gctgcacacg atcagcacat tgtccaccgc
    40021 gacattaagc cccagaacat gattatttcc agggatggga aggtaaaggt ggcagatttc
    40081 ggcattgccc gggcagtcag cagccagacc atcggtgcta cggctatcgg ctctgtccac
    40141 tacatttctc cggaacaggc cagaggcggt ttcagcgatt ccaggacaga catctattcc
    40201 ctgggaatta ccatgttcga gatggtgaca ggtacagttc cttttgacgg ggataatacg
    40261 gtgagcattg ccctggctca tttagagcag gctgtgacgc ccccgtccca gctgaatccg
    40321 gaggttccgg taagccttga ccggattatt atgaagtgta cccagaaaaa gccggagaag
    40381 cgttacagcg acgtctatga gctgattgca gatctgcgcc acgccctggt ggacccggac
    40441 gacgatttcg taacagagga gccggaggtg gatacctctt cccctacgat ggtgatttca
    40501 aacgacgagc tgagccagat caagcaggcc agaaatacag ggcctgtagt gatgaacgga
    40561 caaagctccg gcatgcgggc gccatccgaa acaggacagc acgaaaaacg gcatgacagg
    40621 gagtatggaa acggccggag agagacttac agccggcggg acagccggag cggaggagga
    40681 agaagccagg aatacgatta cgatgagtat gacgattacc aggatgaggg cagttatgat
    40741 tcctataatg actcttatga cggttcctat gacagaggca gggaccgggg agctggaaga
    40801 gacagaggtt ctgaccgtat gccagcctcg ggaagcggtt cttccgggaa aaaggccaga
    40861 aaacagaaga gagactctga tatcaatcct cagatagaga agcttttgac aagcgttgga
    40921 gtggtggctg ctattattat tgtggctgtt ctcattacca tatttgccaa gctgggagga
    40981 attttcaact caggatccaa tggaaataat cctgctcaga cgcagacttc gggacaggag
    41041 actggactga aggatacaga gacacgggtt cccgatttta tcggcctgac agaggaggaa
    41101 gcggaggaaa aggcaaagga cagccacctg aagctgagct atggctatgt gcagtcagac
    41161 gagaagaaaa agggacgcgt cattgagcag aagacggcgg agggaacggt tgtagataaa
    41221 cagtcgaccg tcaaggtgat agtgggagaa ggcggtgaga aggaatctga ggaggagacc
    41281 aaagaatctc atcagattga tctgaccgtt ctgggcctgg aggccctgga tggaaccaac
    41341 gccaagaatc tgctggaggc aaaggggctt accgtctctt tgaagcagga aaacagcgat
    41401 acgattcccg tggatatggt agtgcgctac gagccgcagg aggcggacag aggggacgag
    41461 attgagctct atgtgagcct tggaccgaca gtcagcatgg taaaggttcc tgatttaagc
    41521 ggcatgacag aggaggaggc cggggaggct cttgctgaag ctggacttct gcctgcgccg
    41581 gaggatcaga tcctcaccca gaagagcgac agcgtgaaga ggggaaccat tatcagccag
    41641 acgcctctca tggacgagga ggttccagag ggaagcaccg tcagctacgt agtcagcgag
    41701 ggacgcggca agaagtacgc ggctattgtc aacgacgatt acccgctgaa ggacaatttt
    41761 ggccccagcg gagcctccac cacgatcacc gtggagattg tcatggtgca gacagtgaac
    41821 gggcagaaga gaacgactac tgtaatggat gccagaaaca tgaaaggcga tgtgacgctt
    41881 cccgtccact atgagctgac aggagcggac ggagttctga caggagaact gcagatctgg
    41941 gatctgacta acgacagaat tttaaagacc tatcccctcg aatttatgga ggtcgacgcg
    42001 tagatgacag gaaagattgt taagggaatc gcaggctttt actatgtcca cgacgggcag
    42061 cagaaagtct atgagtgcag agccaagggc gtgttcagaa acaggaaaat caagcctctg
    42121 gtgggagaca acgtagagtt tgaaattctg gacgaggagg cgggcacagg cagcattgtc
    42181 tccattttgg agcggaaaaa ctccctgatt cgtccggctg tctccaatat tgatcaggcc
    42241 ctggtggtat ttgccattac agaacccatg ccgaatctga atcttctgga tcggtttctg
    42301 gttatgatgg agcgtcagaa tattccggct gtcatctgct ttaataaaat tgatttgtca
    42361 tccagggagg agatggagcg cctgcgctcc atctatgccc cggcaggata tgagattcat
    42421 tttatcagca cctatgagga ggcgggactt caggagattc acagactcat acagggaaaa
    42481 acgactgtgc tggcaggtcc gtccggagtg ggaaaatcct ccctgacgaa ttttctccag
    42541 ccggaggcca atatggagac aggcgtagtc agtgaaaaga ttaagcgggg aaagcataca
    42601 acccgccatt cggagctgtt ttttgtggag gagaatacct acatgatgga cacgcctggt
    42661 ttcagctcca tgtatattga ggacttgaag ccggaggagc tgaaggactg ctttccggag
    42721 tttgccccgg aggaggacgg ctgccggttt ttaggctgtg tccatgtggg agagaaggtc
    42781 tgcggagtca aggaggcggt gaaagtcgga actatcagcc gcagccgata tgaaaattac
    42841 ctgcttttgt accaggaatt gaaggataaa aggagatatt aattatgata cgtttagcgc
    42901 cgtctgtgtt aggagcagat ttttcacgcc tgggagagga gatccaggca gtagacaggg
    42961 cgggagccca gtatattcat ctggatgtga tggacggaac ctttgtgccc agcatttcct
    43021 ttggaatgcc ggtgattgaa cggcttcgcc cggtgacgga ccgcgtattt gacgtccaca
    43081 tgatggtaga ggaaccggga cggtatgtgg aggatatgaa gaaggcggga gccgatctga
    43141 tctgcgtcca tcaggaggcc tgcagacatc tggatcggac agtgaaccag attaaggagc
    43201 tggggctcaa ggctgccgtg gccttaaatc cggctacgcc tgtatccacc ctgtcctgca
    43261 ttctggatca gctggatatg gcgcttatca tgtcagtcaa tccaggtttt ggcggccaga
    43321 aatttattcc ttacacactg gaaaagatta ggcagctgcg caggatgagc gatgagagag
    43381 gactgaatct ggatattcag gtggacggag gcgtgggcct tggaaacgtc cgccaggtga
    43441 ttgaggcggg agccaatgtg attgtggccg gttccgctgt cttcaaggga gacgcggcgg
    43501 ccaacactaa ggcgtttctg gagattttta aggagtatga gtaggatgga aggagagacc
    43561 tgcctgatca tcacgggagg aaacctgaac ctggactttg cggagcagtt tctaaaacac
    43621 agaagctacg gctgcgtgat tgccgtagat gggggactgg aggccgctgc cgctctcggc
    43681 gtctgtccgg atgagattgt gggagatctg gacacggtaa atccggctct gtttgactcc
    43741 taccgcagaa aaccagggat tgagctggaa atccaccggc cggagaagga tgagacggac
    43801 acagagctgg cccttctcac agcagagaga aagggctttc atgcggtaca cctgctgggc
    43861 gctttaggcg ggcggatgga tcacgccctg ggcaatgtgc agctgttaaa tcagtgcctg
    43921 caaaacgatg tacatgcaga aatctatgat gagaagaaca gaatctatct agccggcccc
    43981 ggcagaacag agtttgccag ggaacaggca tatgggcaat atatttcttt tcttccgctg
    44041 acagagtcgg tggaggggat taccctgaca ggctttaaat atcctctttc caataaaacg
    44101 atccatctgg gaaccagcct ctgtatcagc aatgagctga cgggagagaa gggaagcctg
    44161 gaatttcaaa agggcattct catctgcatt gagagccacg actgattgga tgaaaaactg
    44221 acctctgaaa aaatatgaaa actgaatgtt ttgtcaagta cagatctgtg ataagataca
    44281 ggtcagaaag gtgcaggaca tctgcataca gtttacagca ggaggcagtg atatgattcg
    44341 aaacaatgat aaggcgtata aaatcgccat gacaggactg atggcggctc tttcctatgt
    44401 agtgtttaca tttggccaga ttaaactgac gcttccaggc ggagacgcta cgtccatcca
    44461 tctaggcaac gcagtctgcg tgctgggggc gctgctcatc ggcggcttct ggggaggcct
    44521 gggaggagcg atcggaatga ccataggaga tctgctggat ccggtttacg tggtctatgc
    44581 gccgaaaacc tttattttaa agctgtgtat cggcctgatt acaggttttg tggctcacag
    44641 gattggaaag atctctgtca gcacagataa gaagcatatt ttaaaatatg tgattctggc
    44701 gtcagccgca ggccttttat ttaacatggc agctgatccg ctgtttggat attactataa
    44761 actgctgata atcggaaagc cggcagctga gctggctctc gtctggaata tcgcctccac
    44821 ctcgatcaac gcggtgatct cggcagctgc gtctgtcctg atctacatgg cggcgcggcc
    44881 tgcgcttcat tcagcgggcc ttcttctccg gttatcataa ggagattatg atgaatgaga
    44941 caggacaaaa aaagattgca atgataaact ccatggcagg gtatggccgc tgttctataa
    45001 cagcggctat tcctgtgctg agcgctttaa aggtacagtg ctgcccggcg cccacggcta
    45061 ttttgtcaaa tcataccggc tatccaagct gttactttga cgactacaca gaaggtctgg
    45121 cgccttacct ggaggagtgg aagaagcttc agttttcctt tgacgctgtt atgactggat
    45181 ttctcggttc cgccgggcag gtccggactg cagtggactt tctcatggaa gtaaagccac
    45241 agggaacgaa ggttctggta gatccggtgc tgggagacaa tggaacgctc tacaggacct
    45301 gtacccagga gctctgcgag gaaatgcggg agctgattca gtacgcggac gtgattacgc
    45361 ccaatctgac agaagcctgc cttctgacgg agactccatg gagcgaaaca ggatggtcga
    45421 aaaacaggct ggcagatttg gcctacaagc tgctattcat ggggccggga gcggtggtgc
    45481 tcacaggcgc ggcaaaaagc cattcgatta tcaatgtagt gctggagcgt ggaaaagaac
    45541 ctgtcttttt cactggaaaa cgggttgaaa caagccgcca cggtacaggc gacgtatttt
    45601 ccgcagtact ggcgggagag atggtccact ccgtgccgtt agaagaggca gtgcgccggg
    45661 cggccacctt tacgagaaag tgcgtggaga ggtcggaaga acttcagatt ccggaaaaag
    45721 aggggctatg tatcgaggaa tgcctgcctt atctgttccg gttaagccgc agagattaaa
    45781 gggacttcag gaaaaggcag aaatgggctt ttcataaaca ggaaactgta gtataatcaa
    45841 ggtcagacta cgttttggct gtcagaacag ccaaatatca ttgatttcaa tgaaaataaa
    45901 agcggatttc aggaaccgct gcaggaggaa gatatgttag atttaagatt tgtcagagaa
    45961 aatccggaga tcgtaaagca gaacatcagg aataaattcc aggacagcaa gctgcctctg
    46021 gtggacgagg tgatcgagct ggacgcgcag aaccgtgcag ttaagaaaga agccgatgat
    46081 ctgagagctg gaaagaataa aattgccaag cagatcggcg gtctgatggc tcagggcaag
    46141 aaggaagagg ctgaggagct gaagaagaag gtaggcgagg acgctgcccg cttagctgag
    46201 ctggagactc tggagaaaga gctttccgag aagattacca aaatcatgat gacaatcccg
    46261 aacattatcg atccgtccgt tccgattgga aaagacgaca gcgagaatgt ggagatccag
    46321 aagtacggag agccggttgt tccggatttc gagattccgt atcacacgga gatcatggag
    46381 cgcttcaacg gaatcgactt agacagcgcc agaaaggtgg ctggaaacgg tttctactat
    46441 ctgatgggag acatcgccag acttcactcc gcagtgattt cctatgcaag agacttcatg
    46501 attgacagag gctttaccta ctgcgtgccg ccgttcatga tccgcagcaa tgtagtgaca
    46561 ggcgttatga gctttgccga gatggacgcc atgatgtaca agatcgaggg agaggatctg
    46621 tacctgatcg gaaccagcga acactccatg attggaaagt tcatcgacac agttctcaag
    46681 gaggaagagc ttccgaagac gctgaccagc tattctccat gcttcagaaa agagaagggc
    46741 gctcacggaa tcgaggagag aggcgtatac agaatccacc agtttgagaa gcaggagatg
    46801 atcgttgtct gcaagcctga ggacagcatg aagtggtatg acaagctgtg gcagaacaca
    46861 gttgacctgt tccgctccct ggatattcca gtgagaactc tggagtgctg ctccggagat
    46921 ctggctgact taaaggtgaa gtctgtggac gtagaggcat ggtccccgag acagcagaag
    46981 tatttcgagg tgggaagctg ctccaactta ggagacgctc aggcgcgccg cttaaagatc
    47041 cgcgtaaacg gcgagaacgg caaatacttt gcccacacct tgaataacac ggtagtagct
    47101 ccgccgcgta tgctgattgc cttcttagag aacaacttac aggcagacgg atctgtcaga
    47161 atcccagagg tattacggcc gtatatgggc ggaaaagcgg agatccgtta gagagtgcag
    47221 aaagcagaat aatagataga aagaagatgt tttcctgtga taatgagagg catgggaagg
    47281 catcttcttt tttgggctct ttgtcaagag ttggggtaaa tgtatttttg aggcacagga
    47341 atgatgtttc tgtgcctctt tacg
//
LOCUS       DBMDUW010000016        45230 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_739_length_45230_cov_2.674422, whole genome shotgun sequence.
ACCESSION   DBMDUW010000016 DBMDUW010000000
VERSION     DBMDUW010000016.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 45230)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 45230)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45230
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_739_length_45230_cov_2.674422"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..142)
                     /locus_tag="ACZPCR_04905"
     CDS             complement(<1..142)
                     /locus_tag="ACZPCR_04905"
                     /inference="COORDINATES: protein motif:HMM:NF012906.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230246.1"
                     /translation="MAGDDKDNEKTDTGERKVVKQQSPVQNPVLWSTENPYLYKLASM
                     IKR"
     gene            complement(139..1980)
                     /locus_tag="ACZPCR_04910"
     CDS             complement(139..1980)
                     /locus_tag="ACZPCR_04910"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: protein motif:HMM:NF014763.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor domain-containing diguanylate cyclase"
                     /protein_id="HIR1230247.1"
                     /translation="MKIILVFMIFGFVLTSLLDFNRAMQAREYQLELDAMVRVASQGS
                     LVLEIKLSGYLKKLSAMAEFFQEGELHTEKNMEILRNISNEMQQDFQRFALADLEGNS
                     WVTNGSRLDVSEQPYFKNALEKKYTITDNKHSQVIENNHIFIISVPILDGKDQVRGVL
                     YGVVEVDKFQLHQDMDGEEQKYRVVDRNGDYILRGNPDFFHFDSNNLFENISNINMSQ
                     SIDQVKARIQKGEAFLDEFSRDGINYVIYFSPLKINDWYSITVMKQSQILDYIRKMSG
                     KDIYIIMAKVMAAVALLCGTIILFLMKEKKDALSMYHQMKVNNEMLRAAIGKSDALIL
                     IYDLKTRQLQCLNPECVEELSLPEIIENAPEQILQFLPEGENSKRQIQDLFASLEEIR
                     GTQVFQLVFEDGEKRYHYQIRISALLDDENKVFQCVGLAENITEQLVMRQEIEIFRQK
                     AGTDYLTGLYNRGKGTELITELLNNMDPETESHAFIILDLDNFKGLNDTLGHQTGDAA
                     LQDVASILQRHFRNYDIICRLAGDEFVVLINNIPEEIVQKNLEILLKKLNLSYGQEKT
                     VQISASIGVAMAARDGRDFQTLYQKADEALYEAKKSGKQTAVIYGKK"
     gene            complement(2207..2665)
                     /locus_tag="ACZPCR_04915"
     CDS             complement(2207..2665)
                     /locus_tag="ACZPCR_04915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008706997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FoF1 ATP synthase subunit delta/epsilon"
                     /protein_id="HIR1230248.1"
                     /translation="MDSEKSFGLEIYSSSERFFQGRARLITLPSTDGGHTFLPHHENT
                     VIALVPGITRFIPAEAPQKYDGDREKQEERVIATGAGFAEMVNNRMKVFVHSAERPED
                     IDVNRAREAKERAEEQLRQEQSLREYYRNQRELARAMSRLSAAGMKNKTQ"
     gene            complement(2694..4091)
                     /gene="atpD"
                     /locus_tag="ACZPCR_04920"
     CDS             complement(2694..4091)
                     /gene="atpD"
                     /locus_tag="ACZPCR_04920"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018594303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HIR1230249.1"
                     /translation="MNKGRIIQVMGPVVDVLFENGDLPHIEDALRVKNGEKTCVMEVS
                     QHLGNRTVRCIMMSASEGLCRGMEVEASGKGIQVPVGDKTLGRLFNVLGETLDGGSSL
                     EEEEHWVIHRDPPSFSEQKPVVEILETGIKVIDLLAPYAKGGKIGLFGGAGVGKTVLI
                     QELIQNIATEHGGYSIFTGVGERSREGNDLWTEMKESGVLSKTALVFGQMNEPPGARM
                     RVAETGLTMAEYFRDRERQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLATE
                     MGKLQERIASTKEGSITSVQAVYVPADDLTDPAPATTFAHLDATTVLSRKIVEQGIYP
                     AVDPLESTSRILEADIVGEDHYETARRVQEILQKYRELQDIIAILGMEELSEEDKNIV
                     FRARKVQKFLSQPFHVAENFTGIPGKYVPLKETIRGFKMILDGKMDAYPENSFFNVGT
                     IDEVIAKTEEGKTEQ"
     gene            complement(4104..5000)
                     /gene="atpG"
                     /locus_tag="ACZPCR_04925"
     CDS             complement(4104..5000)
                     /gene="atpG"
                     /locus_tag="ACZPCR_04925"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009247287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HIR1230250.1"
                     /translation="MAGTKEIQTRMKSIQDTMKITNAMYMISSSKMKRAKKILADTEP
                     YFFEVHTALERILRHLPEEERESRYLDSRPEIKPEDRKRALIVVTADKGLNGSYNHNI
                     IKMAEDELKKPGHTKLYVLGVVGRQYFSKKDADMDGSFRYTVQKPTMHRARMITETVA
                     GGFLDGMFDEVSILYTQMVNAIKEEPVLETLLPLKHPFQKRISLPVDVHREEIRLFPS
                     AGEVMDNIVPSYIVGVIYGALVESYASEHNARMMAMQASTDNAKAMLKELSIQYNRAR
                     QAAITQEITEVIGGAGAQKKKR"
     gene            complement(5025..6536)
                     /gene="atpA"
                     /locus_tag="ACZPCR_04930"
     CDS             complement(5025..6536)
                     /gene="atpA"
                     /locus_tag="ACZPCR_04930"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007864575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HIR1230251.1"
                     /translation="MSSISSEDIISILKEEIKNYDDRCRGEETGTVISVGDGIARIYG
                     MDQAMYGEILLFENGLKGMVQDIKEDSIGCILFGKDTGISEGSRVYRTKRKAGIPVGE
                     AFMGRVVDALGAPIDGKGEIKAEDYRPVEQEAPGIVERKSVDRPLETGILSIDSMFPI
                     GRGQRELIIGDRQTGKTSIAVDTILNQKGKDVICIYVAIGQKASTVAKLVSTLAEHGA
                     MEYSIVMAASASDCAPLQYIAPYSGTALAEYFMYRGKDVLIVYDDLSKHAVAYRALSL
                     LLERSPGREAYPGDVFYLHSRLLERSSRLSDTLGGGSITALPIIETQAGDVSAYIPTN
                     VISITDGQIFLETDLFFAGQRPAVNVGLSVSRVGGAAQTKAMKKASGSIRIDLAQYRE
                     MEVFTQFSSDLDASTKQQLQYGKTLMELLKQPLGSPLSLHEQVITLCAARHQVFMGMD
                     VKKVRAFQRELLNYFDGSFPKIGEEIEKTGELSDEMEKQISETANQYRADQTV"
     gene            complement(6533..7045)
                     /gene="atpH"
                     /locus_tag="ACZPCR_04935"
     CDS             complement(6533..7045)
                     /gene="atpH"
                     /locus_tag="ACZPCR_04935"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019160514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit delta"
                     /protein_id="HIR1230252.1"
                     /translation="MAGTFDNYARALWELHVPENRVSEAAELLKDNPVLWEALKNPVI
                     CLKEKERIIDRIFPEEMRGFLKTVCSHGRASSLMEILAAYDKYKKEGRGILKAVITCV
                     TPPEEKQRCQIESFLKKKFGKMAVEFEIRIDPALLGGFILEAEGVEYDRSLRGFYRRL
                     REYLCGGESA"
     gene            complement(7026..7511)
                     /gene="atpF"
                     /locus_tag="ACZPCR_04940"
     CDS             complement(7026..7511)
                     /gene="atpF"
                     /locus_tag="ACZPCR_04940"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HIR1230253.1"
                     /translation="MSLVYNIINLIVLCLLLKHFLIKPVLGIMDKRQAFIEAGLAEAK
                     NAREEADALKEQYEAALKDARAQSGRILENARIRAGEEYSRILEEADMKAAESLKCGR
                     EQLEAEQKKAMEQLKSRIAETALCAAEKAAGSGRGELADLAAYDRFIEEAGESHGGNI
                     R"
     gene            complement(7550..7774)
                     /gene="atpE"
                     /locus_tag="ACZPCR_04945"
     CDS             complement(7550..7774)
                     /gene="atpE"
                     /locus_tag="ACZPCR_04945"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007864555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HIR1230254.1"
                     /translation="MTTLIAIGAAVAVLTGIGAGIGIGIATSKAVEAIARQPEAESKI
                     SKALLLGCALAEATAIYGFVIALVIILFLK"
     gene            complement(7816..8478)
                     /locus_tag="ACZPCR_04950"
     CDS             complement(7816..8478)
                     /locus_tag="ACZPCR_04950"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HIR1230255.1"
                     /translation="MEELNCRVAFTIPLFGGIPIYDSVAVTWVIMAALVLLSKILVRN
                     LRVEDPGKAQLFLESSIGFLRDFFLDLVGEEGKNYIPYLISTAVFIGAANLIGIVGFV
                     PPTKDLNMTAALAVISIAVIEYAGFHKKGARGFLKSFAEPVAVILPINILEIFIRPIS
                     LCMRLFGNVLGSFVVMELIKLVVPVIIPIPFSFYFDIFDGVIQAYVFVFLTALFIKEQ
                     LD"
     gene            complement(8824..9648)
                     /locus_tag="ACZPCR_04955"
     CDS             complement(8824..9648)
                     /locus_tag="ACZPCR_04955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006779313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HIR1230256.1"
                     /translation="MSTVMEMLSYPFMVRALLGGILVSLCASLLGVSLVLKRYSMIGD
                     GLSHVSFGALSVALAAGWSPLKVSIPVVVLAAFFLLRITERGQIKSDAAIAMISASAL
                     AVGIIVTSMTTGMTTDVSSYMFGSILAMSREDVEFSAALSAVVLFLFLFCYNKVFAVT
                     FDENFAKATGVRVGFYNVLIAVLTAVTIVLGMRMMGAMLISSLIIFPALTSMRIFKSF
                     HGVVVSSGILSIICFFIGMVISYIYSTPAGASVVVVNLGFFLLFSLIQTVERIIKK"
     gene            complement(9645..10355)
                     /locus_tag="ACZPCR_04960"
     CDS             complement(9645..10355)
                     /locus_tag="ACZPCR_04960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003509267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HIR1230257.1"
                     /translation="MGMLLKCEHADFGYENQDAVVDANLEVKTGDYICIVGENGSGKS
                     TLMKGILGLLKPTSGKITVSDELKKAGIGYLPQQTAAQKDFPATVREVVLSGCLGKRG
                     NRPFYSKKERELADYNMHRLGITDLRKQCYRELSGGQKQRTLIARALCATDKLLVLDE
                     PITGLDPSAIQDFYHMIKKLNREEQVAVLMVSHDIQNIVHQADKILHLKREILFYGSV
                     SDYVKSRVGKGFLGGEEE"
     gene            complement(10340..11401)
                     /locus_tag="ACZPCR_04965"
     CDS             complement(10340..11401)
                     /locus_tag="ACZPCR_04965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006779311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HIR1230258.1"
                     /translation="MTRRGINRAAWAAVWSASVLLSGCSRAEVQLENPADDGTLKIVT
                     TVFPYYDFTRQIAGSLLDSGEAELTLMVPAGMDSHSFEPTPADLIELQSADIIICNGG
                     AMEHWFQQVSDSLDLDEQRVITMMDYVDTVEEEIVEGMEAETHDHAEDHIHEAGENEE
                     EGGHYDDGHQEEIEYDEHIWTSPVNAMKLSAVIADTLCMSDPDHEKIYRENLSAYERQ
                     LSELDQIFREIVDQADGRLVVFGDKFPLRYFFDEYGLEYRAAFTGCSTDTEPSAKTIA
                     YLIDKVREFQIPAVYYLELSSHRVAEIIGEETGAQPLLFHSCHNVTRREFDSGVTYLE
                     LMEQNAVNLRKGLDKWECY"
     gene            complement(11394..12053)
                     /locus_tag="ACZPCR_04970"
     CDS             complement(11394..12053)
                     /locus_tag="ACZPCR_04970"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002603442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HIR1230259.1"
                     /translation="MYKLCIFDLDGTLLNTLTALTYATNLTLRTFGLGDITIEDTKRM
                     VGDGYKTQMERALSHFGQENMKYYDQSLTEYMKNFSANCMRGVEPYDGIPHLLLFLKE
                     QGIKAAVFSNKPHDQAVENIETVFGKDIFDMILGQKEGLPKKPSPEGALLICRELHVK
                     PEECLYLGDTNTDMETGIAAGMDTVGVTWGFRDRKELASFHPRYLADHPAQVEEILSH
                     D"
     regulatory      12266..12458
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            12648..13394
                     /locus_tag="ACZPCR_04975"
     CDS             12648..13394
                     /locus_tag="ACZPCR_04975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004844320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0000041 - transition metal ion transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HIR1230260.1"
                     /translation="MTKHEKQIIAVSVTLAACLGVSFTANAMHIMEGALPAGYCIAWG
                     LICLPFLLAGFFSIRRVLQENRRALTLLAMSGAFVFVISSLKIPSVSGSCSHMTGTGL
                     GAILFGPAAMSVLGLIVLLFQAVLLAHGGLTTLGANTFSMAVAGPFVSYFLFSVLKRL
                     PVNKKISIFLAAFLGDLITYCVTAFQLAIAHNSATSFSAALRENMIIFAGTQLPLAVV
                     EGILTVVVIIGLEAYARPELKAVGFLKEEY"
     gene            13397..13738
                     /locus_tag="ACZPCR_04980"
     CDS             13397..13738
                     /locus_tag="ACZPCR_04980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003021521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HIR1230261.1"
                     /translation="MEKKKSNAALVIILLVTAALISFAPLFVLKDAEFGGADDRGNTL
                     IETTDPDYEPWASPILEVILGGELPGEVESMLFCVQTGIGVGIIAFIMGRFVERKKWM
                     KDTENDGGALS"
     gene            13765..14532
                     /gene="cbiQ"
                     /locus_tag="ACZPCR_04985"
     CDS             13765..14532
                     /gene="cbiQ"
                     /locus_tag="ACZPCR_04985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005945019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0032778 - P-type cobalt transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HIR1230262.1"
                     /translation="MPTIDRLSYESRLRFVHTGEKFFFSLFTLLLCVGSRSIPLAVYV
                     FMTTGILTVYKGKIPVIEYLKLLGVPLVFLGMNSLVLGIAICREPLELFAISMGQWYL
                     TASTETVLYGLRIFLTAMASVSCLYALSCHTPMTDFILFLKRIHVPALLIELMVLIYR
                     FIFILLDCAHAISISQRARLGNKDFKTSLRSFSALISSLFIRAVSRSSILYDAMESRC
                     YDGVLNVLSEEQRPRKREICFIIFYELSALFVLWLTA"
     gene            14546..15400
                     /locus_tag="ACZPCR_04990"
     CDS             14546..15400
                     /locus_tag="ACZPCR_04990"
                     /EC_number="3.6.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005945016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HIR1230263.1"
                     /translation="MKQGDVILKAEHLCFSYDDGQSFSLNDLSLEIRKGSRTAFLGPN
                     GSGKSTFFLCCNGIRRPSSGCLYFHEKPVSYTKKALLELRQKVGIVFQDPDNQLFSAS
                     VYQEISFGLLNLGIEQKESAKQTEAIMEQLEITPYRFKPVHALSGGQKKQVSIADILV
                     MKPEIVIMDEPASALDPKHTSLVNHAVSQMTAEGITVMMATHDVNYAFSWADEIIILK
                     DGRVLDQGDPVSVFSNKELLHDACLEQPAVLTLFDALCQKKILKNSLEIPRNMNTLIQ
                     YIQKYGGL"
     gene            complement(15473..16456)
                     /locus_tag="ACZPCR_04995"
     CDS             complement(15473..16456)
                     /locus_tag="ACZPCR_04995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007713198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bile acid:sodium symporter family protein"
                     /protein_id="HIR1230264.1"
                     /translation="MKALEKISDFFGKYMAFIVLAVAALALFAPDTCLWVQTSWVNYL
                     LMVVMFGMGLTLKLEDFKLVFTRPKDIIAGCMAQFTIMPLLAWLLGKAFHLDPALMAG
                     VVLVGTCPGGTSSNVITYLSKGDVPLSVGMTSVNTLLAPFLTPAITYLLLRTTVTVDM
                     VSMFMSIVQVVIVPIALGFIINKMFGKATQKLVKVLPSVSVIAICLIVAAVVSHNAEK
                     IMSTGALVFVVVILHNLLGYACGLGLGRALGLSVPKMKALSIEIGMQNSGLATSLAGT
                     AFPTLAMATVPGAVFSVWHNISGAVLANLYNRWEEKPAKEKKAGKAVSQAV"
     misc_binding    complement(16622..16878)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(16934..>17568)
                     /locus_tag="ACZPCR_05000"
     CDS             complement(16934..>17568)
                     /locus_tag="ACZPCR_05000"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008372314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - tRNA queuosine(34) biosynthetic
                     process [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HIR1230265.1"
                     /translation="KSNNNRNFQKEMDRLIEKNQGKGIIPTLFLHSCCAPCSSYVLEY
                     LSQYFKITVYYYNPNIYPPEEYEERTMEVERLIRELPAKYPISFISGEYRPELFYEAV
                     KGHEGDKEGGERCSICFSLRLEEAARLAKEGNFDYFTTTLTISPLKNAARLNQIGEEM
                     GEKYGVSYLDSDFKKKNGYKRSTELSKKYNLYRQDYCGCVFSMRERQTKK"
     assembly_gap    17569..17578
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(17867..19000)
                     /gene="rpoD"
                     /locus_tag="ACZPCR_05005"
     CDS             complement(17867..19000)
                     /gene="rpoD"
                     /locus_tag="ACZPCR_05005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006780938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HIR1230266.1"
                     /translation="MEKERDNFLEKLKKLVDLAKTKQNALDITEINDFFAADNLSPEQ
                     MEQIYNYLEQNNIDVIPEVIDETALNDDLLMLDDVDDDFMKNGEEEEIDLDAIDLLEG
                     IGTEDPVRMYLKEIGTVPLLSAEEELRLAKRKAEGDVSAKERLIEANLRLVVSIAKRY
                     TGRGMSFLDLVQEGNLGLIKGVEKFDYTKGYKLSTYATWWIRQSVTRALADQARTIRV
                     PVHMVETINKMSKMQRKLTLELGYEPSVAELSAALDMSEDKVMEIMQIAREPASLETP
                     IGEEDDSNLGDFVADGNVVTPEGNVESVMLREHIDALLGDLKERERQVIVLRFGLEDG
                     HPRTLEEVGKEFNVTRERIRQIEAKALRKLRNPVRSKRIRDFL"
     gene            complement(19139..20029)
                     /locus_tag="ACZPCR_05010"
     CDS             complement(19139..20029)
                     /locus_tag="ACZPCR_05010"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001727 - lipid kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol/lipid kinase family protein"
                     /protein_id="HIR1230267.1"
                     /translation="MKKMLFIFNPRSGRERLRTKLLDILDLFVKAGYEVTVHVTQSAG
                     DAQKQVEKKGGGVELLVCSGGDGTLNEVVSGMMAWSREKRPQLGYIPAGSTNDFAASL
                     DLPKNMLRAAAIAVAGRPFAIDVGKFGDGRYFVYVAAFGAFTEVSYKTPQETKNVLGH
                     QAYMLEAVKRIAGLKSYRMKFFWDDQELEEDFILGMVTNTISIGGFKGLVQPRVALND
                     GEFEVMLVRKPRTPKDIQSIVSCLINKDAENDCVYMFRTSNLRMESEEIVDWTLDGEY
                     GGGVKEICIENLREEIVVKR"
     gene            complement(20080..21219)
                     /gene="mutY"
                     /locus_tag="ACZPCR_05015"
     CDS             complement(20080..21219)
                     /gene="mutY"
                     /locus_tag="ACZPCR_05015"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HIR1230268.1"
                     /translation="MENSWIKRQYGSLMQVEAENQTMDRNERLLAVREPLLSWYHKNR
                     RILPWREQPESYRVWISEIMLQQTRVEAVKPYFARFMEALPDVKALASVEEETLLKLW
                     EGLGYYNRARNLQKAARVCMDEYGGQLPASYESLLSLPGIGSYTAGAVASIAFGIPEP
                     AVDGNVLRVLSRLFESREDIGKQSVKRKMENELRAVIPKELPGEFNQALIELGAIVCI
                     PSGKPLCSQCPCSTLCLARRRQTTGEIPVKAGKKERRREEKTVFIIEYEDKAAIRKRS
                     AKGLLASLYEFPNLPGHLKEEEIPDALAIGREDILAIEPLPEAVHIFSHVEWHMTGFR
                     VMIKRELPHQYPMKRVEEIFETYPLPNAFQAYTALLKRNTKHILP"
     gene            complement(21288..22268)
                     /locus_tag="ACZPCR_05020"
     CDS             complement(21288..22268)
                     /locus_tag="ACZPCR_05020"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin--[biotin carboxyl-carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HIR1230269.1"
                     /translation="MKTEILRYLKEADGYISGQELCGQFHVSRTAVWKVMKQLEAEGY
                     EIEAVRNRGYRLKTAEDILSREEILSSMKGQWAGKEVLYFDETDSTNTEAKKAAENGA
                     PHGTLTVAERQTGGKGRRGRTWDSPGGTGIFMSLVLRPDMAPVHASMLTLVAALAAAR
                     GIEQCAQVKPLIKWPNDIVINGRKVCGILTEMSADPDCINYVVTGIGINVNMEQFPEE
                     IRQVAASIYTESGKKIRRSVLISAVMEAFEEYYGVFMKTADMSGLLEEYNGKLANCGR
                     TVRVLDPAGEYSGTAQGINSQGELLVEMDDKTVKTVISGEVSVRGIYGYV"
     gene            complement(22276..22587)
                     /locus_tag="ACZPCR_05025"
     CDS             complement(22276..22587)
                     /locus_tag="ACZPCR_05025"
                     /inference="COORDINATES: protein motif:HMM:NF042675.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6637 family protein"
                     /protein_id="HIR1230270.1"
                     /translation="MLMTEGQRKNRASRLKKETADIAAGLGIVIFSILVFINPDRYRL
                     LFPVIFLMAAGINLVNGMDRMSTSGGRRAKKRRTGFLFLGLAAALLLMALFSAASILW
                     G"
     gene            complement(22749..23681)
                     /locus_tag="ACZPCR_05030"
     CDS             complement(22749..23681)
                     /locus_tag="ACZPCR_05030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003509410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HIR1230271.1"
                     /translation="MFILFVVLAVVALLVLLSCIKIVPQAQAIVVERLGAYLDTWSVG
                     VHFKMPFVDRVAKRIILKEQVVDFPPQPVITKDNVTMKIDTVVFFQITDPKLFAYGVE
                     NPIMAIENLTATTLRNIIGDLELDQTLTSRETINTKMRAALDVATDPWGIKVNRVELK
                     NIIPPAAIQDAMEKQMKAERERREAILRAEGEKKSTVLVAEGQKASAILEAEAEKEAA
                     ILRAEAEKQKMIKEAEGRAEAILKVQQANADGIRFIKEAGADNAVLQLKSLEAFAKAA
                     DGKATKIIIPSEIQGIAGLVKSLAEIGEKDEAAK"
     gene            complement(23683..24120)
                     /locus_tag="ACZPCR_05035"
     CDS             complement(23683..24120)
                     /locus_tag="ACZPCR_05035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HIR1230272.1"
                     /translation="MERIIWLTAFVVLIGIEAATMTLCTIWFAIGALVSFFLTLAGVG
                     KYGQLAAFFAVSCVLFFFTRPVALRYVNPKTVKTNVDELIGKKAVITEDVDNDRAAGT
                     AVLDGREWTARSADGSVIEAGALAEIMEIQGVKLIVRKIREEK"
     gene            complement(24220..25005)
                     /locus_tag="ACZPCR_05040"
     CDS             complement(24220..25005)
                     /locus_tag="ACZPCR_05040"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003509412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HIR1230273.1"
                     /translation="MITSTSNSQVKQVGALAKKAKARKESGLFLVEGEKMFSELPRER
                     LDRVYVSESFLRQQGERAEALLSGCRYETVTDEVMRAMSDTQTPQGILALCRQFSYQL
                     SDILGGNQMHLAVLETIQDPGNLGTILRAGEGAGITGVIMNRTTADIYNPKVIRSTMG
                     SIYRVPFLYTDDLQETIRQVKKAGVRLFAAHLKGERSYDQEDYTGNTGFLIGNEANGL
                     SAETADMADCYIKIPMLGKVESLNAAVAASILMYETARQRRND"
     gene            complement(25002..26939)
                     /locus_tag="ACZPCR_05045"
     CDS             complement(25002..26939)
                     /locus_tag="ACZPCR_05045"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007870097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA];
                     GO_process: GO:0009435 - NAD+ biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HIR1230274.1"
                     /translation="MRDGFLRVAASTPEVKVADVQFNREEICRKIQEGRKNGVKIMVF
                     PELCLTAYTCGDLFLQKSLLTAVKRELKALADFTKGSDMLVFAGLPWEYNHKLYNTAA
                     AIQDGRLLGIVPKLWIPNYGEFYERRHFNPWEFGNVTVEFDGQKVPMGTKLLFACKNA
                     ENLVVGAEVCEDVWVLNPPSSAHAAAGATVIVNCSASDETTGKADYRRSLISGQSARL
                     LCAYVYANAGEGESTQDLVFGGQNIIAENGTVLKESRRFCSETIVCDIDLERLECERR
                     RMTTYQTEGQADYEIIEFELEDEEAEQEKEYSHLERFVDPSPFVPGSDAERAKRCEEI
                     LMIQAMGLKKRLVHTHCQNAVVGISGGLDSTLALLVTVKAFEMAGLPKEKIYSVTMPC
                     FGTTDRTYHNACLLTKKLGATLLEVDIKDAVNIHFRDINHDPSVHDVTYENSQARERT
                     QVLMDIANQTGGMVIGTGDMSELALGWATYNGDHMSMYGVNASVPKTLVRHLVRYYAD
                     TCGEEELKAVLLDILDTPVSPELLPPEDNGTIAQKTEDLVGPYELHDFFLYYVLRYGY
                     QPGKIYRLALYAFQGTYDRETILKWLKVFYRRFFNQQFKRSCLPDGPKVGSAAVSPRG
                     DLRMPSDAVSRLWLEELEALS"
     gene            complement(27024..27797)
                     /locus_tag="ACZPCR_05050"
     CDS             complement(27024..27797)
                     /locus_tag="ACZPCR_05050"
                     /EC_number="6.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA];
                     GO_function: GO:0061503 - tRNA threonylcarbamoyladenosine
                     dehydratase [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HIR1230275.1"
                     /translation="MEEFERTGLLLGSEGLARLGTSTVAVFGVGGVGSHCIEALARSG
                     VGRLILVDSDVVSRSNINRQSVAFQETIGTFKTKVMEEIIRQISPETEVITIEAFVLP
                     ENLEKLLSEVEGTIDYIVDAIDTVAAKLALAEYAKEHGIPLIASMGTGNKLHPELFQI
                     ADISETSVCPLCRVMRRELKKRGIERLKVLYSRETPIKPREQTEKSSESGLEEPEKIE
                     GTAPRKRAVPGSVSFVPPAAGMMLAGCVIRSLAGIDDNL"
     gene            complement(27784..28110)
                     /locus_tag="ACZPCR_05055"
     CDS             complement(27784..28110)
                     /locus_tag="ACZPCR_05055"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230276.1"
                     /translation="MKNISASIRTFALTYSGRANRRDESEIWRLDCEKLCKMTKTKLT
                     QGDKSAIFNKAKLFNVSVDERDREEPFSRGRSGSFFLYLIKNRRERDVGYIPLFDDED
                     RKNGRI"
     gene            28164..29591
                     /locus_tag="ACZPCR_05060"
     CDS             28164..29591
                     /locus_tag="ACZPCR_05060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008722785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009847 - spore germination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="spore germination protein"
                     /protein_id="HIR1230277.1"
                     /translation="MEISNKLDANLRHFHQLLRVNENFDVVYRVIQIGGRDACVYFVD
                     GFAKDDTLLRILQGFTSLKPDAVPQTAHEFSKLFIPYGEVDLLTDDAEIAVQVLSGVP
                     CLFVDGYSKCFAIDCRTYPARGVAEPDKDKVLRGSRDGFVETLVFNTALIRRRIRDPQ
                     MTIEVMQAGSKSHTDIALCYMEGRVDQDLLSTIKKRIERLHVDALTMNQESLAECIYP
                     HKWFNPFPKFRFSERPDTAAASILEGNLVILVDNSPAAMILPSSIFDIVEEADDYYFP
                     PLTGTYLRVSRMVISFLTLFLTPVWLLFMQNPDWIPSWLEFIRLSDEIHVALIFQLLI
                     LEFAIDGLRLAAVNTPSMLTTPLSVIAGIVLGEYSVKSGWFNSETMLYMAFVTVANYS
                     QASYELGYALKFMRVFLLIITAFFNLWGFVLGTVLCFLALVFNKTIAGKSYIYPLIPF
                     SFSELKKRLIRTRLPHADGQGEEDR"
     gene            complement(29599..31014)
                     /gene="pdxR"
                     /locus_tag="ACZPCR_05065"
     CDS             complement(29599..31014)
                     /gene="pdxR"
                     /locus_tag="ACZPCR_05065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003509434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070279 - vitamin B6 binding [Evidence
                     IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:2000142 - regulation of DNA-templated
                     transcription initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MocR-like pyridoxine biosynthesis transcription
                     factor PdxR"
                     /protein_id="HIR1230278.1"
                     /translation="MERDSSRYLDDEGTLRYMRVYQYYRSLIEEKKLEAGAKLPSIRT
                     CSIQLNLSRTTVETAYLMLAAEGYIAAKPQSGYYVTNLGQARRAESRQQTRKKKKELL
                     FDFSSSRVDRESFRFEVWRRYVKSALRQDERLLSYGEPQGEGELREELSRYLRRHRNV
                     VCTPEQIVVGAGVQSLLHILCPMIRERRQVLMNNESFHQGRTVFEDYGFLVSGMESGR
                     EELPADSIFYLTPSQITSWGEVMGIGERTKLIKTAMEKNLLLIEDDYNSEFSYYNRPA
                     PSLQGLSGGKGVVYMGTFSRMLLPSIRMSFMVLPPELLPVYQRRGEFYNQTASKAEQI
                     ALCQFIRDGHLEAQIRKSRRLYLQKAKLLCEDIQELFGEKAKAYPGEAGFLVLAELQT
                     ELSGEEIRQRAEEAGVGVRTVDEKEWNRAFLSRGSSPDSTETAIGLPIRRILLSCASV
                     PAEHYKEALLRLKQSLGMQLQ"
     gene            complement(31107..31970)
                     /locus_tag="ACZPCR_05070"
     CDS             complement(31107..31970)
                     /locus_tag="ACZPCR_05070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HIR1230279.1"
                     /translation="MEKLNGRELWKDISLLLLGSLIYGIGTYVFVIPANIAPGGATGV
                     ALMVNYVTGLPVGILTLLLNVPLLALAWFYLSKKFAISTAVTTTLCSLVLDFVVPFIV
                     PAYSGDRLLCSLYGGVIVGAGMALIFIAGSTTGGTDILGYVLQKKRPHISIGRALMIV
                     DGIILAVSIFVFGNIEAALFGMIALYVQTKVIDTIIYGGEAGSMATIITSNPDDISDK
                     VIGELDRTATLIPARGMYSKQDTNVLLCTVRKSQFSRLKKIVYEADPNAFVMVTDTSE
                     VFGLGFKNFTE"
     gene            complement(32081..33535)
                     /gene="guaB"
                     /locus_tag="ACZPCR_05075"
     CDS             complement(32081..33535)
                     /gene="guaB"
                     /locus_tag="ACZPCR_05075"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015554889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HIR1230280.1"
                     /translation="MGTIIGDGITFDDVLLVPAYSEVIPNQVDLSTYLTKKIKLNIPL
                     MSAGMDTVTEHRMAIAMARQGGIGIIHKNMSIKEQAEEVDKVKRSENGVITDPFYLSP
                     EHTLKDADELMGKFRISGVPITEGRKLVGIITNRDLKFEEDYSKKIKECMTSENLVTA
                     KEGTTMLEAKKILAKARVEKLPIVDDDFNLKGLITIKDIEKQIKYPLSAKDAQGRLLC
                     GAAVGITANVLERVEALVNAKVDVVVLDSAHGHSANVIHCVKMIKEAYPDVQVIAGNV
                     ATGEAAKALIEAGVDAVKVGIGPGSICTTRVVAGIGVPQISAIMDCYAVAKEYGIPVI
                     ADGGIKYSGDITKAIAAGGSVCMMGSLFAGCDESPGTFELYQGRKYKVYRGMGSIAAM
                     ENGSKDRYFQTDAKKLVPEGVEGRVAYKGMVEDTVFQLLGGLRAGMGYCGASNIPTLQ
                     ETGKFVKISAASLKESHPHDIHITKEAPNYSIEQ"
     gene            complement(33694..34389)
                     /locus_tag="ACZPCR_05080"
     CDS             complement(33694..34389)
                     /locus_tag="ACZPCR_05080"
                     /inference="COORDINATES: protein motif:HMM:NF016119.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase domain-containing protein"
                     /protein_id="HIR1230281.1"
                     /translation="MKEKNSGIGNRLKHMCAAAAAAILLVVMLLSAALLAGKYCRDQR
                     GKAAYQLTRKIAGVEEREDGEEQETDIPVPLLDETRLLQMNPDYAGWIYIPGTPVSYP
                     VVYPENNNEYLDRTFDGQKNPCGCLFFEASYPPLSSKNTVIYGHNMKSGEMFGSLKKY
                     REEEFLKKNKTIYLCVEKEWTEYQIQKVYLADSRDKSPYESDGGALGKTRLTLSTCHG
                     RKQRLIIQAERNG"
     gene            complement(34400..45070)
                     /locus_tag="ACZPCR_05085"
     CDS             complement(34400..45070)
                     /locus_tag="ACZPCR_05085"
                     /inference="COORDINATES: protein motif:HMM:NF049299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HIR1230282.1"
                     /translation="MDTEKEDGSFLTVGDAVSAVLDYYNSHPYYSYGGIDAAEEKNGQ
                     LVFTVYTGISGNPEYFMVLGSDPEKDSLIFKSVPWLPEDKTRSPRLIYADYSNNSDYG
                     TFGTYEEYRETQTESAVFASARLISDAEAAADGTLIPKTVLKNEYYKPGELVRDKNGN
                     LIQAFEYQEILKTEIIEVEETVWKEIPAERRQDGTYLFTADASYTDSFGVPHTNQGQD
                     QTIEFKAVLLEKNIILSEDDVKILTEDLMPGFTAGKPMGSASYFIHVKKARARACLDA
                     DTMEMQGENSYVVQADLSYPGQEKLYEDQKTRTYPSQVFERPIRQRVKIFKDIYTNPD
                     GTYDNNTYGADETEAEPGFQFKAYLKSNLERLYRDEEGTIVWMDRNGNELPYENMLHS
                     LCPQSAGNGKLNVPKLYTKVLHNVKSTLTSINGNNILADYQDPETADENAAKQTPFST
                     SIAPGGAGVIVNAALYSYRGNNENTEKTHQIRKQANKGYTRLLETEDRLVQGENGPVT
                     IQEYNYDKFFDALETVNTDKWDTKAQTYTSWRPLGNQAKRTEYAVNNAKASDGVRQFA
                     VTWYLDDEAAKLLKDNGEKEDAFKNDREQNLSSETVYDEALNAALEKAYHYLKPFFQY
                     DLDQIYAICWDSEEDGGSDGDKTTLEVSQKNGDQSGYYGLSEYLPYGAYVVAEQQPKK
                     RMENRQYKIDCPKEIQIPSVYEAKKAKDQETALSRKYVYQTALSLNEQAEEERFLIRF
                     GEEWDQHASEQREYVIRAHNHTGDFEIYKYGLEPDKLKGTISYDGGSYDYQGFSIGQK
                     PFKPWKDYYYPARQIPGQSLTGEGKYCIYGSVSEQAGTAKKVRFEKKTEAVYKDVKAM
                     QGIQTACEGQYGPMLVPYSVLDPIKGAYEPEAFRGYADQKFRNTFYSSRLRIEKLDSE
                     THENLLHDGAVFMIYKAARDKETGKAQFYEKDTLITGSREFLEAMGASDITPIKREKE
                     RGEKERQKAEEKRTAPGMQYSGIVKAQTPVCREEDKIVMKDTAGNETGQFAAFSTLHE
                     IEMKKEDTNREPKEYRLQAGGYLTTPEPLGAGVYVLAEIPPRGYVRTAPIAVEIYSDQ
                     VSYYEEGKREQRVLAAVYEDGKNGESEDKKTSEKAGTAQIYVENIPIKLKVEKLKKKG
                     TVTFEIGERIDGSLTEIGGNPALQYAYDDNGVYLGYAYPKGTLERLSALKKVGEQVEL
                     VYDGTHFAGYGYVTKDRETNDDKNPYTAGARMTLFDAIELKPSGDTEDFSYEGLEIRR
                     SVNGNVKEMIVKRGYAGKKTELVKEKGHIWKEGTVERPDTEILYYDLDNLSLTWKERI
                     DGKTKLLGWDKSHQKVSVDQMQKDEEGTLFAFKGGKPYLEFSGGDLTKLSYHPVDKVL
                     KGTFATPCRITKTGEWKMGEGTLVYHLDSYGNRDSLVDPQTGMAYVVEPKLNEEGKHT
                     ADRILVWPVETAKDKNGMVTARDKITTSRIATVGENREGKKDSAVIEPNNQSDQKLEE
                     WEKPQYSHTETGFVNGTWGSQEESHKEQTVVQNKKGQNMNREPLFDLNNGKLLNFMDP
                     VYDEHGLVLYYQRSDSCYDKGTELYDRNGDFVRYKNSDNLEEYNRGAYALDGHDKLFD
                     GKADAEHQIQDRLYHRLGESYLLENSWISSDKTPNDPFEEELTEGQPDLLKRLPAGTY
                     IVEELEVPSGSGYTKAFPVGVTVEEEETVKSVSIWDDTTKGYFEKIDGQEGSGEETFC
                     FTNRQMEGAELALYPAKKVSDPSEPDGWRLEKISDVPFRFETTNSRTGSREYQEMLWR
                     TGSIPHYVEGIPAGPYILEELSAPPGFLRAQPKEIWVEHTPDLQNFRLYNDHTKTAFY
                     KYRKDGTKKQLLPGAEFTLYEAETDENGAVVYDKNGNPVPDDSKKIDSWITDDATDYT
                     DTIDLKNYPNAGGMKGQTGFTLELQNMYETYGVMGSGFSWSAERRAQRESKNSRVWIL
                     EDGSRVITGKNEETGEETVTFPLSMSLEERAGFKAAYEARKEGQLALKWVISRRASVE
                     KIESLDVSLEGGKPQKYPEAAKLFLRVAETGKTVLADIRYNGSSFEYHYKFDYCALPH
                     VGPYANAWLSEGGGRRIDYLPSGTAYVLEETKAPEGFIKADPILVKVGEEHEIQQHEI
                     FNEKNALAVSKRSSVTGKELAGAELVLYKADEHGMLNQTESYLIDSWISGTDGVYTEK
                     DFINGLIPEGFAEGDLKPHTLLHLSEGYYYLTEQKAPAYYQAAVPVKFYYSGTKNETV
                     QIETMFNKPIKGELIVHKTDQKENSLQGVVFELSAYDEKGRMVSGFPRKVSDINGTVH
                     VMELPVGRIDRENGNIEPYQYRLKEILPPEGFAANPQIYTFTFENGEGGYCEDGTLHT
                     VIHEQNVKNDVTKIYLEKRELEGLGDSGTEGIFVEGACMAVYRISEINDKGEYTYTEE
                     DLVTEWITSSEEKRHLITGLTAGCSYVLAEKKAPEGYALMEPVLFTLKEDGRGISSIS
                     NSLSAVRVHYRKETAENSDSDSIDSIAFRGRTAVRTELTVFDEEGRDILTIAETGGSH
                     QLSRKDGLTENELYTFEERTFYSDGKSCISRRITKRVHFDEDGFFVFQGRRAVGTRIA
                     VTDQDGVSITEFEPLPEQMETVIQNRVNPENPQIILKNKGAQAGAPIKRGQPAEGIIT
                     WHNTSRKAQDIVIRAEISDNLEVFDAGEGTEESGNGGKRNLVWKIRQAAPLSQGSVKF
                     IAETVSGESAEIAAELELGKEKQLKGRKTVPVLQEHCLTVYNGLTGSAAEQTEKETSL
                     FTVQLWNQKGDELAGTYSYTGSREGTLKSGDTIELAGNEFVTIDPVLKGCTYQVSRKE
                     NGVKTESHETEGVISEDGTAAWFTRNTEDTSERAVFSKGETYLITETTIYSGDQTEVS
                     SCLSFTLNDQADISVVGGYDKQTELEVQKTDLLTGKAVEGAVLQLYRLEKGEEILECQ
                     WTSGEDAFSAEGLLPGRTYRLKEKEAPKGYGYAMDITFTLNPSGAPEILCMEDRQTQI
                     VISKKDITNQEELPGAHLQVLDRNGIVQEEWISERTPHKIQGKLTAGETYILRETIPA
                     DGYALAKDITFTVNKDGSVNYVEMRDDTTKVRIYKNVYQGLDKEIQKALSSDAKEMPV
                     KGAILQILNEDKTPALFEGREMIFTTGETFAFLERKLTAGKTYWLHEVKPAPGYGYAE
                     DVKFTVSTDGAIDIVVMEDKPTKAVISKKDITGEEEISGCEMRLATEDGKEIERWISG
                     TKPHEITGKLEADRTYILTEIKPAPGYSYAEEIKFTVSHDGSVNRVEMRDDVTKTEIL
                     KIDGSSKRPLAGAELEILDEKGNSIERWISEGEPHKLYQKLEAGKTYILHERKAPAGY
                     ALMEDQKFTVSRLGETTTVTAENRKKRGGGGNDFVIRIKKTDEAGMPLSGAAFTVTDE
                     NGKELALETEADGTEFKLLLEKPQTVIVRETAAPDGYEALNKSYKIRIPAKGDAELLG
                     GDHMFCQDAENSYVFIAVNQKKEKMKGKITVSYDETLYGNGTLSIRGQGTEILPAKTG
                     DDFPVKLLEALFAGSAAGLLILCSRRKRRKDS"
BASE COUNT        10640 a        12499 c         8756 g        13325 t
ORIGIN      
        1 cacgctttat catactggcc agtttataca aataaggatt ctccgtactc cataaaacag
       61 gattctgcac tggcgattgt tgcttcacca ccttcctttc tcctgtgtct gttttttcat
      121 tgtctttatc gtctcctgct attttttacc gtaaattacc gctgtctgtt ttccgctctt
      181 tttcgcctcg tataaagcct catctgcttt ttggtacaga gtctgaaaat ctcttccatc
      241 tctggctgcc atagctactc caatggaagc tgaaatctga actgtttttt cctgtccata
      301 tgaaagattc agctttttca gcaaaatttc cagatttttc tgtacgattt cttctggaat
      361 gttgttaatt aacaccacaa actcatctcc agccagccgg cagatgatat cataatttct
      421 gaagtgccgc tgcagaatag atgccacatc ctgaagtgcc gcatctcctg tctgatgtcc
      481 cagcgtatcg ttcagccctt taaaattatc taagtctaat ataataaacg catggctttc
      541 tgtctcagga tccatgttat taagaagctc tgtaattagt tctgttccct ttcctctgtt
      601 atacaaacct gtcaggtaat ctgttcctgc cttctgccgg aaaatttcta tttcctgtct
      661 catcaccagc tgttctgtga tattttcagc cagtcccaca cattgaaata ccttattctc
      721 gtcatccagc aaagcgctga tacggatctg atagtgatat cgcttctccc cgtcttcaaa
      781 aaccagctga aatacctgcg taccccggat ctcctccagg ctggcgaaca gatcctgaat
      841 ctgcctttta gaattttcac cttctggcag aaactgcaga atctgctccg gagcattctc
      901 aattatctcc ggcagagata attcctccac acattccgga ttcagacact ggagctgtct
      961 tgttttcaga tcataaataa gaatcagagc gtcgcttttt ccaattgcag cccgaagcat
     1021 ctcattattt accttcatct gatggtacat agaaagcgcg tccttttttt ctttcatcag
     1081 gaaaagaata atagtaccgc aaagcagagc tacggctgcc attacttttg ccattatgat
     1141 gtagatatct tttccagaca tctttcttat ataatcaaga atctgagact gcttcattac
     1201 ggtaatagaa taccagtcat taattttaag aggagaaaaa taaatcacat agttgattcc
     1261 atctctgctg aattcatcaa gaaacgcttc tcccttctgt atcctcgcct tcacctgatc
     1321 tatgctctgg ctcatgttga tattgctgat attctcaaac aggttgttgc tgtcaaaatg
     1381 aaaaaaatct ggatttcctc gaagaatgta atccccgttc cgatcaacaa cgcggtattt
     1441 ctgctcctca ccatccatat cctggtgaag ctgaaattta tccacctcta ctaccccgta
     1501 gagaactccc ctcacctgat cttttccatc taaaatcggt actgaaatga taaaaatatg
     1561 attattttct atcacctggg aatgtttgtt atctgttatc gtatactttt tttcaagggc
     1621 atttttaaaa tagggctgtt ctgatacgtc cagccgtgat ccatttgtca cccaggagtt
     1681 tccttccaga tctgccagag caaatctctg aaaatcctgc tgcatttcgt ttgaaatatt
     1741 tctcaggatc tccatattct tttctgtgtg aagttctccc tcctgaaaaa actccgccat
     1801 cgcactcagc ttttttaagt atccgctcag ctttatctcc agcacaaggc ttccctgact
     1861 tgcaacacgc accatagcgt ccagctctaa ttgatattcc ctagcctgca ttgctctgtt
     1921 aaaatcaagc aaagaagtaa gcacaaatcc aaaaatcatg aatacaagga taattttcat
     1981 aaaataacta taatatctct tcttcataac tgcttcccct tttctatttc tgacttttat
     2041 tttatcatca actgtctggg cagacaaccg tttgaagaaa gatttatgca ctatttctgt
     2101 ataaatttca gcaaaaaaat acagaaagcg gtatccgcgc tctctatgcg cccgttttct
     2161 gtattttttt ctatattttc ctgtttattt ttatttctgc tgttttttat tgtgttttat
     2221 ttttcattcc tgctgcgctt agacgcgaca tggctctggc cagttccctc tggtttctgt
     2281 agtattccct aagagactgt tcctggcgca gctgttcctc cgctcgttcc tttgcctccc
     2341 gggcccggtt aacatcgata tcctctggtc tctctgccga atggacgaat accttcatcc
     2401 tgttattcac catttccgca aatcctgccc ctgtagcaat cactctttct tcctgctttt
     2461 ctctgtctcc atcgtatttc tgcggagcct ctgctggaat aaatctggta attccaggaa
     2521 ccagagcgat aacggtgttt tcatgatgcg gcagaaaggt atgtcctccg tctgtagagg
     2581 gaagggtaat taacctggcc cttccctgaa aaaaccgttc actgctggaa taaatttcaa
     2641 gaccaaaact cttttctgaa tccataaagc tcctcctcaa aacaggttcc tggttactgc
     2701 tctgttttcc cctcctctgt ctttgcgatt acttcgtcaa tggttcctac attgaaaaat
     2761 gaattttccg gataggcatc catttttccg tccaaaatca tcttaaaccc acgaattgtc
     2821 tctttcagcg gcacatactt tcctggaatt cctgtaaagt tttcagccac atgaaagggt
     2881 tgtgacagaa acttctgaac cttcctggcc ctgaatacga tattcttgtc ttcctctgaa
     2941 agttcttcca ttcccaagat ggcaataata tcctgaagtt ctctgtactt ttgcagtatc
     3001 tcctggacgc gtcttgccgt ttcatagtga tcttcaccca caatgtcagc ttccagaatc
     3061 ctggatgtag actccagtgg atctacagcc ggataaattc cctgctctac aatttttctg
     3121 gaaagtactg tagtcgcatc cagatgagca aatgttgttg ccggggctgg atcagtcaag
     3181 tcatcagccg gcacatatac cgcctgaacg gaggtaatgc ttccttcctt tgtggaggca
     3241 attctctcct gaagttttcc catctctgtc gccagcgttg gctgatagcc tacagccgac
     3301 ggcattctcc ccagaagagc cgatacctca gatccagcct gcacaaagcg gaaaatatta
     3361 tcaataaaca gaagtacatc ctgacgctcc ctgtcccgaa aatattctgc catggtaaga
     3421 cctgtctcag ccacacgcat tcgtgctccc ggcggctcat tcatctgccc aaataccagg
     3481 gctgttttcg agagaactcc tgattctttc atttctgtcc acaaatcgtt tccttccctg
     3541 gatcgttctc cgactccagt aaaaatggaa tatcccccat gttctgtggc aatattctga
     3601 atcagctcct gaatgagcac cgttttgcca actcccgctc ctccaaacag accgattttt
     3661 cctcctttag cgtaaggagc caaaaggtca atcactttga ttcctgtctc cagaatctct
     3721 actaccggct tctgctctga aaaggaagga ggatctctgt ggattaccca gtgttcctct
     3781 tcttccagag aactgcctcc gtccagagtt tctcccagaa cattaaacag gcgtcccaaa
     3841 gttttatctc ctacaggaac ctgtattccc tttcctgaag cctccacctc catgccgcgg
     3901 cagagtcctt cgctggcgga catcataatg caccgtacgg ttctgttccc cagatgctgg
     3961 gaaacctcca tcacacaggt tttttctcca ttttttaccc tcagggcatc ttctatgtgg
     4021 ggaagatccc cattttcaaa taaaacatct acaacaggtc ccataacctg tataattctg
     4081 cctttgttca tacaccgtct cctctaacgc ttctttttct gagccccggc tcctccaatt
     4141 acttctgtaa tttcctgagt aatcgccgcc tgtctcgctc tgttatactg aatagaaagt
     4201 tccttcaaca tcgcttttgc gttatctgtg gaagcctgca ttgccatcat tctggcattg
     4261 tgctcactgg cataggattc cacaagagcg ccgtaaatga ctcctactat atagctcggc
     4321 acaatgttat ccattacctc tcctgcggaa ggaaacagac gtatttcttc ccgatgtaca
     4381 tctacaggaa gagagatccg cttctgaaat ggatgtttta atggcagaag cgtctcaagc
     4441 acaggttcct cctttatggc atttaccatc tgagtataaa gaatcgacac ttcgtcaaac
     4501 attccgtcca gaaatccccc tgctactgtt tccgtaatca tcctcgccct gtgcatggtt
     4561 ggtttctgaa ctgtgtaccg aaagcttcca tccatatctg catccttttt ggaaaaatac
     4621 tggcgtccta caacccccag cacatagagc tttgtgtggc caggcttttt cagctcgtct
     4681 tctgccattt taataatatt gtgattatac gagccgttta gtcccttgtc cgctgtaact
     4741 actatcaacg cccgctttct gtcttccggc tttatctccg gccggctgtc cagataacgg
     4801 ctctccctct cctcctccgg caagtggcgc aaaattctct ccagagccgt atgaacctcg
     4861 aaaaaataag gttccgtatc agccagaatc ttcttggccc gtttcatttt agaagaggaa
     4921 atcatataca tggcattcgt aatcttcatt gtatcctgga tgctcttcat ccttgtctga
     4981 atttcctttg tgccggccat ttaatcaccc gcctttctct gctgctaaac agtctgatcc
     5041 gctctgtact ggtttgcagt ctcagagatc tgcttttcca tttcatccga aagctcaccc
     5101 gtcttttcaa tctcctctcc aatcttaggg aaacttccgt caaaataatt taaaagctct
     5161 ctctggaacg cccggacctt tttcacatcc atccccataa acacctgatg tctggcagcg
     5221 cagagtgtaa tcacctgctc atgaagactt aaaggactgc ctaacggctg tttcaatagt
     5281 tccatcaatg tttttccata ttgaagctgc tgttttgtgg aggcgtccag atcagagctg
     5341 aactgagtga atacttccat ttcccggtac tgagccagat cgattctaat gcttcccgat
     5401 gcttttttca tagcctttgt ctgtgcagcg cctcctacac gggacacaga aagccctacg
     5461 ttaacagctg ggcgctgacc tgcaaaaaat aagtctgtct caaggaaaat ttgtccgtct
     5521 gtaatggaaa ttacatttgt aggaatatag gctgatacat ctccagcctg cgtctcgata
     5581 atcggaagcg cggtaataga accgcctccc agagtatcgc ttaaacggct ggatcgctcc
     5641 agcagcctgg aatgaagata aaatacatct cccggatagg cttcacgtcc tggcgaacgc
     5701 tccaaaagca gggacagcgc ccggtaagct accgcatgct tgcttaaatc atcgtagaca
     5761 attaatacat cctttcctct gtacataaaa tactctgcca gagctgttcc agagtaggga
     5821 gcaatatact gaaggggcgc acagtcactg gctgaagccg ccataacaat ggaatactcc
     5881 attgccccat gttctgcaag ggtggatacc agcttagcta cagtagatgc cttctggcca
     5941 atcgccacat aaatacagat tacatctttt cccttctggt ttaaaattgt atctacagca
     6001 atagaagttt ttcctgtctg cctgtctcca ataatcagtt ctctctgtcc ccgtccaatg
     6061 ggaaacatgg aatcaatcga aagaatccct gtctcaagcg gtctgtctac tgattttctt
     6121 tccacaattc caggagcttc ctgttccacc ggacgataat cctctgcctt tatttctccc
     6181 tttccatcaa tcggcgctcc cagggcatcc actacgcgcc ccataaacgc ctctcccact
     6241 gggattcctg cttttctctt cgtcctgtac acacggcttc cttcgctgat tcctgtatcc
     6301 tttccaaaca aaatacagcc gatgctgtcc tctttgatat cctggaccat tcccttcaat
     6361 ccattttcaa acagaaggat ttctccatac atcgcctgat ccatgccata aattctggcg
     6421 attccatctc ccacggaaat gacggttcct gtctcttccc ccctgcatct gtcatcgtaa
     6481 tttttaatct cttccttcag aatcgaaata atatcctctg aactgatcga actcacgcgc
     6541 tttcacctcc gcataaatat tctcttaacc gcctgtaaaa acctctgagg cttctgtcat
     6601 actctacgcc ttccgcttcc aggataaatc cacctaaaag ggcaggatct atacggattt
     6661 cgaactctac tgccattttt ccgaatttct ttttaagaaa actttcaatc tgacatcgct
     6721 gtttctcttc aggaggcgtt acgcaggtaa tcactgcttt caggattcct ctgccttcct
     6781 tcttatattt gtcatacgcg gctaaaatct ccatcaaaga ggacgctctt ccatggctgc
     6841 agactgtctt taaaaatccc cgcatctcct ccggaaagat tcgatcaatg atccgttctt
     6901 tctccttcaa acatatgaca ggatttttca atgcttccca aagaacagga ttatccttca
     6961 agagttctgc cgcttccgaa acgcgatttt ccggcacatg aagttcccag agagctcttg
     7021 catagttatc gaatgttccc gccatggctt tcacctgctt cctctataaa acgatcatag
     7081 gctgccaaat ctgccagttc ccctcttccg cttccagccg ctttctcggc tgcacagaga
     7141 gctgtctcgg caattcttga cttcagctgc tccatggcct ttttctgttc agcctccagc
     7201 tgttccctgc cgcatttaag gctttctgca gctttcatat ccgcctcttc cagaatacgg
     7261 ctgtattctt cgccagctct tattctggca ttctccagaa tacggcctga ctgggctctg
     7321 gcatccttca aggcggcttc gtattgttct ttcagagcat ctgcctcttc cctggcattt
     7381 tttgcctccg ccaatcctgc ctctatgaag gcctgccttt tatccatgat tcccaaaaca
     7441 ggttttatga gaaagtgctt taaaagcaga cagagaacaa tcaggtttat aatgttataa
     7501 accaagctca tattaaattg cagcacctta tttcacctgc ctttcataat tacttcagga
     7561 acagaataat aacaagtgca ataacaaagc cgtaaatcgc agttgcctct gccagggcgc
     7621 agcccagcaa aagtgcttta ctaattttac tttctgcttc cggctgcctt gcaatggctt
     7681 ccactgcttt tgatgtggca attccgattc caattcctgc tccaatacct gtaagaactg
     7741 caacagctgc tccaatcgcg attaatgttg tcataatttt ttctcctctt ctgataatat
     7801 aattttaatt tttccctaat ccagctgctc tttaatgaac agagccgtca ggaacacgaa
     7861 tacatacgcc tgaatcaccc catcaaatat gtcaaagtaa aaactaaatg gaattggaat
     7921 gattacaggt acaaccagct taataagttc catcactaca aatgaaccca gcacatttcc
     7981 aaacaaacgc atgcagaggg atattggtct gataaaaatc tccaaaatat tgattggcag
     8041 aatcaccgcc acaggctcag caaaactttt taaaaatccc ctggctcctt ttttgtgaaa
     8101 tccagcatat tcaattactg caatgcttat cacagccaag gctgccgtca tgttcagatc
     8161 ctttgtcgga ggtacaaatc cgactattcc tatgagattc gctgcaccga taaaaacagc
     8221 tgtagaaatc agataaggaa tataattttt tccctcctcc cccactaaat ccaggaaaaa
     8281 gtctctgaga aacccaatgg agctttccag aaacagctgg gcctttccag gatcctctac
     8341 cctgagattt ctcaccagga tctttgataa gagaactagc gccgccatga ttacccaggt
     8401 cactgctacc gaatcataaa tcggtatgcc gccaaacaac ggaatcgtga aggccaccct
     8461 gcagttaagt tcctctatca gggcatttga aagagcttcc gttttaatcc ctccttttca
     8521 aataaaaaat gtactcaggc acattcccgc gccgatcaca gccgcctgcg gcatgtttct
     8581 tcttcgcgcg agtgcgcttc ctaagcggag cgttttttat gacataggac gaattttcct
     8641 atgtcatgaa aaaggcagaa aaacacatga tatgcttttt ccgccttctc cccttaattg
     8701 ccccctatta tacgcctatt tggctcagaa caaaatctga aaaactgcca aaatttcgtg
     8761 ggcaaatatt tattcttttg tctaaataat tacttgattt tttgatttaa tttcatttat
     8821 ttattatttt ttaataattc tttcaactgt ctgaatcagt gaaaacagca ggaaaaatcc
     8881 caaattcacc accactacgc tggctcccgc aggcgtagaa tagatatagg aaatcaccat
     8941 tccaatgaaa aagcagataa tggaaaggat acccgatgat accacaactc catgaaagct
     9001 cttaaatatc cgcatggaag ttaaggccgg aaaaataatc aggctcgaaa tcagcatagc
     9061 tcccatcatt cgcattccca gcacaatggt cacagccgtc aggacggcta tcaggacatt
     9121 ataaaagcct acccgcacgc cagtagcttt ggcaaaattt tcatcaaagg tcactgcaaa
     9181 taccttattg tagcaaaata aaaataaaaa cagaaccact gcagagagcg cagcagaaaa
     9241 ttccacatct tcccggctca tggccagaat acttccaaac atatagctgc ttacatctgt
     9301 cgtcattcct gtggtcatgg aggtgacgat gattccgaca gccagcgcac tggcagaaat
     9361 catggcgata gccgcatcgc ttttaatctg tccccgttcc gtaatacgga gcagaaaaaa
     9421 ggcagccagc actaccaccg gaatcgatac cttgagaggc gaccagcctg cagccagagc
     9481 cacagagagc gctccgaagg acacatggga aagaccgtct ccaatcatag aatatcgttt
     9541 taacacaagg ctgacaccca gaagggaggc gcacagggaa acaagaatgc cgcccagcag
     9601 cgcccgaacc ataaacggat acgaaagcat ttccatcact gtgctcattc ttcctcacct
     9661 cccaaaaatc cttttcccac tcggcttttt acataatctg atacagaacc gtaaaacagt
     9721 atctcccttt tcaggtggag aatcttgtcc gcttggtgga caatgttctg aatatcgtgg
     9781 gataccatga gaactgccac ctgttcctcc ctgttcagct tcttaatcat atggtaaaaa
     9841 tcctgaatcg cagacggatc aaggcctgta atcggctcgt ccaacactaa aagcttatct
     9901 gtcgcgcaga gcgccctggc gatcagagtt ctctgcttct ggcctcctga aagctccctg
     9961 tagcactgtt ttctcaaatc tgtaattccc agacgatgca tattataatc tgccagctct
    10021 ctctcctttt tggaataaaa ggggcggttt ccccgctttc caaggcagcc ggaaagcacc
    10081 acctctctta ctgtagccgg aaaatccttc tgggctgcag tctgctgtgg aaggtatcca
    10141 atccccgcct ttttcagctc atcagacacc gtaattttcc cggatgtagg ttttaaaagc
    10201 cctaaaatcc ccttcatcag ggtacttttt ccggaaccat tttctcctac aatacagatg
    10261 taatctcctg tctttacctc cagatttgcg tccaccacag cgtcctggtt ttcatatcca
    10321 aaatctgcgt gctcgcattt taataacatt cccatttatc taatcctttt ctcaaattta
    10381 cggcgttctg ctccatcagt tccagatagg tgacgcctga atcaaattcc cgccgggtca
    10441 cattgtggca ggaatggaat aaaagaggct gcgcccccgt ctcctcccct atgatttcag
    10501 ccacccggtg gctggaaagt tctaaatagt agacagctgg tatctgaaat tcccgtactt
    10561 tatcaatcag ataggcaata gtcttggcac ttggttccgt atccgtgctg cagccggtaa
    10621 atgctgcccg atactccaga ccatactcgt caaaaaaata ccggagagga aatttatctc
    10681 caaacaccac cagccttccg tccgcctgat ctacaatttc tctgaaaatc tggtcaagtt
    10741 ctgaaagctg tctttcgtag gcagacagat tttcccgata aattttctca tggtcaggat
    10801 ctgacataca aagagtgtca gcaatcacag cagaaagctt catggcattg acaggtgacg
    10861 tccagatatg ctcatcatac tcgatttcct cctgatgtcc gtcatcatag tgcccacctt
    10921 cctcctcatt ttctcctgcc tcgtggatat gatcctctgc gtgatcgtga gtttccgctt
    10981 ccattccctc cacaatctcc tcctccacag tgtccacata gtccatcatg gtaataaccc
    11041 gctgctcatc taagtccaga gaatcggaga cctgctgaaa ccaatgctcc atggctcctc
    11101 cgttgcagat aataatatct gcgctctgaa gctcgatcag atctgccgga gtcggttcaa
    11161 aggaatggct gtccataccc gccggaacca tcagagtaag ctctgcctca ccggaatcca
    11221 gaagggaacc tgctatctgc ctggtgaaat cataataggg gaacaccgtc gttactattt
    11281 ttagtgtccc atcgtctgcc gggttctcta actgaacctc tgcgcgggaa cagccagaca
    11341 gaagaactga ggcagaccat accgcggccc acgccgcccg atttatccct cttctagtca
    11401 tgagacagaa tctcctccac ctgggccgga tggtctgcca gataccttgg gtgaaaggaa
    11461 gccagctcct tcctgtcccg aaagccccag gtaactccta ccgtatccat accggccgca
    11521 atgcctgtct ccatgtctgt atttgtatct cccagataca ggcactcctc cggctttacg
    11581 tgaagctctc tgcagatcaa gagcgcgcct tccggagacg gctttttcgg aaggccctcc
    11641 ttctgtccca gaatcatatc aaagatatct ttgccaaaaa ccgtttcaat attttccact
    11701 gcctgatcat gcggtttatt agaaaataca gctgctttga tcccttgttc cttcagaaat
    11761 aaaagaaggt gggggattcc gtcatagggc tccactcccc tcatacagtt agcagaaaaa
    11821 ttcttcatat attctgtcag agactggtca taatacttca tattctcctg tccgaaatgg
    11881 ctgagagctc tctccatctg agttttataa ccatctccca ccatacgctt tgtatcctct
    11941 attgtaatat ctcccaatcc gaatgtacga agcgtcaggt tcgtcgcata ggtcagagca
    12001 gtcagcgtgt tcaataaggt tccgtctaaa tcaaaaatac agagcttgta cataaagtca
    12061 ttctcctttc cgcaagtaac gctgcatttt ttctgttttg atcttgtcta gcgtcagtgt
    12121 acaaggagca acatgccgta ttgccctttg tacactgacg ctatcatatt ccaaaacaaa
    12181 aaaagttgca atctttttaa catttctaca gatattcata tgtttctttt cggttgactt
    12241 tctatcctgt tttccctata atagtttcga ttctatatgg tgcggtgtct gcgttttcat
    12301 tccgcagaag aatagagaag cgaggtgaaa ttcctccacg gtcacgccgc tgtaaaagaa
    12361 gagtttcctc tttttatgcc actgagtctg atactgggga aggcgagagg aaatgtggac
    12421 gcttgagtca gaagaactgc ccgccagaat agaagatctc gcctgcgaga ttcccgcctg
    12481 acagagtgcg aaatgatctg ccacggcaaa atctgcctgc cgctcccgtg aaaggacggt
    12541 acgcaggacg gtgtatgccc tgccgtcagt ctgccctgta aattcatctc acagcaggga
    12601 cagatgcatt gtggagatgg gccccacaaa gaatgaaagg agtcattatg acaaaacacg
    12661 aaaaacaaat tattgccgtg tctgtgacgc tggctgcctg ccttggagtt tccttcacgg
    12721 caaatgcgat gcacattatg gaaggcgcac ttccagccgg ttactgcatc gcctggggac
    12781 tgatctgtct tccatttctt ctggccggat tcttctcaat ccggagggtt ctgcaggaaa
    12841 acagaagagc gctgactctt ctcgccatgt caggagcctt tgtctttgta atttcctccc
    12901 ttaaaattcc atctgtcagc ggaagctgtt cccacatgac aggaactgga ctgggagcta
    12961 tcctgttcgg tcctgcggcc atgtctgttc tgggactgat tgtactcttg ttccaggccg
    13021 ttctgctggc tcacggcggg cttaccaccc tgggagctaa cactttttcc atggcagtcg
    13081 caggtccttt tgtatcttat ttcctatttt cagttttaaa aaggctgcct gtaaataaaa
    13141 aaatttcgat tttcctggca gcattcttag gcgatctgat tacctactgt gttactgcat
    13201 tccagcttgc catagctcac aattccgcca ccagcttctc tgccgctctg cgggaaaata
    13261 tgattatttt tgctggtacg cagctgcccc tggctgtagt agagggaatt cttactgtag
    13321 tagttatcat tggactggaa gcctatgcca gaccagagct taaagctgtc ggctttttaa
    13381 aggaggaata ttaattatgg aaaagaaaaa aagcaatgct gcgcttgtca ttatccttct
    13441 ggttacggcc gcgctgattt ctttcgcccc tctttttgtt ctgaaggatg ctgaattcgg
    13501 tggggcggat gaccgcggaa atacattgat cgaaactaca gatccagact atgagccatg
    13561 ggcctctcct atcctggagg tcattctcgg cggggagctt cccggagaag tagaaagtat
    13621 gctcttctgc gttcaaaccg gtattggtgt gggcattatt gcctttatta tgggacgctt
    13681 tgtagaacgc aaaaaatgga tgaaagatac agaaaatgac ggcggcgctc tgtcataaga
    13741 aaaacgcaaa aaaggaggcg gcttatgccc accattgaca gactcagcta tgagtcacgg
    13801 ctgcgttttg tacatacagg agaaaaattt ttcttttcgc tgttcactct gcttctctgt
    13861 gtgggcagcc gctccatccc tctggccgtc tatgtattta tgacaactgg gatcctgact
    13921 gtttacaagg gcaaaatccc agttattgaa tatttaaagc tccttggagt ccccctggtc
    13981 tttctgggaa tgaattctct ggtcttaggg atcgccattt gccgggaacc tctggagctg
    14041 tttgccattt caatgggaca atggtatctg acagccagta cagaaactgt tctctacggc
    14101 cttcggatat tcctgaccgc catggcgtcc gtttcctgcc tgtacgcgct gtcctgtcat
    14161 acacctatga cagattttat tctctttcta aagcggatcc atgttcccgc tcttttaatc
    14221 gagcttatgg tactcattta tcgttttatt tttattcttc tggactgcgc tcatgctatt
    14281 tccatatccc agagagcccg ccttggaaat aaggacttca aaacttctct gcgttctttc
    14341 tccgctctga tatcttcact ttttatccgg gcagtcagtc gttccagtat actctacgat
    14401 gccatggagt ctcgctgcta tgacggagtt ttaaatgttc tgtcagagga acagcgtccc
    14461 agaaaacgtg aaatctgctt tattattttt tatgagctgt cagccctctt cgttctctgg
    14521 ctgacagcct gaagggagga agcttgtgaa acaaggcgat gtgattttaa aagcggaaca
    14581 tctatgtttt tcttatgatg acggacagag tttttcctta aatgacctgt ccctggaaat
    14641 caggaaggga agcagaacag cctttctggg ccctaacggt tctggaaaat ccaccttctt
    14701 tttgtgctgc aacggaatcc gcaggccctc gtcaggatgt ctgtattttc acgaaaagcc
    14761 tgtgtcctat acgaaaaagg ctctgctgga gctgagacag aaggtaggca ttgtattcca
    14821 ggatcctgac aatcagctgt tttctgccag cgtttaccag gaaatttctt ttggccttct
    14881 caatctgggg attgaacaaa aggagtctgc caaacagaca gaggcaataa tggagcagct
    14941 ggaaatcact ccttaccgtt tcaagccagt tcacgctctg tcaggaggac agaaaaaaca
    15001 ggtttctatt gccgatattc tggttatgaa accggaaatc gtcattatgg acgaacctgc
    15061 atctgctctc gatccgaaac atacatctct cgtcaatcat gcggtcagtc aaatgacagc
    15121 ggaaggcatt acagttatga tggctaccca cgatgtaaat tacgcctttt cctgggcaga
    15181 tgaaattatc attctgaaag acgggcgcgt actggaccag ggagatccag tctctgtctt
    15241 ttcaaataaa gagcttctcc atgacgcctg cctggaacag ccggcagttc tgacactttt
    15301 tgacgctctc tgtcaaaaga aaatcttaaa aaacagttta gaaattccca gaaatatgaa
    15361 tactctgata cagtatatac aaaagtacgg cggcctgtaa ccagtccgcc gtgctttttc
    15421 tatattctcc gaaaattctt ctcttcttca cttttaaaaa actcttcttt ttttaaacag
    15481 cctggctgac tgcctttcct gctttcttct ctttagctgg tttttcctcc cagcggttgt
    15541 acaggtttgc taacacagct cctgaaatat tatgccatac agagaacaca gctcccggaa
    15601 ctgtagccat cgccagagtc gggaaagcag ttcctgctaa ggatgtagcc aaaccagaat
    15661 tctgcatacc aatttcaata gagagagcct tcatctttgg aacactcaat cccagagcac
    15721 gtcccaggcc caggccgcag gcgtagccta acagattgtg gagaattact actacaaaca
    15781 caagagcacc tgtagacata atcttttctg cattgtgaga tacaacagca gctacaatca
    15841 gacagatagc gattacggaa acgcttggaa gaacctttac aagcttctgt gttgcctttc
    15901 cgaacatctt attgataata aagcccagag caatcggaac gataactacc tgcacaatag
    15961 acatgaacat gctgaccata tcaacagtaa ccgttgtgcg caggagtaaa taggtaatcg
    16021 ccggtgtgag gaacggagcc agcagtgtgt tgacacttgt cattcctaca gacaacggta
    16081 catctccttt agaaagatag gtgattacgt tgctggaagt tcctcctgga catgtaccta
    16141 caagcactac gccagccatc agcgcaggat ccagatgaaa agcttttcct aacagccatg
    16201 ccagaagagg catgatagta aactgagcca tacagcctgc gatgatatct ttcggacgcg
    16261 tgaataccag cttaaagtcc tccagcttca gggtcaatcc catgccgaac ataacaacca
    16321 tcaaaagata attaacccat gaggtctgca cccacaggca ggtatcaggt gcaaacagag
    16381 ccagagctgc tactgccagc acgataaacg ccatatactt tccaaaaaaa tcactgatct
    16441 tttctaatgc tttcattttc aatctttcct cctgttatcc ttttcagaca cagccttttt
    16501 attctgcgaa gcattccggc tgccaggctc tgcagcgcct ggcaaaatag agttaattcc
    16561 tgcatagcat ttttatttca caggatgaga tttcctctga aataaaaaaa cctctgtctc
    16621 ataaagagac aaaggttaaa atcctctgcg gtaccactct tcttgctggc aaaaccagcc
    16681 gctccgccca catatcaaac aatatgggat aatataacgg ttatcagccg ttcaaaccta
    16741 ctaagccgga aatctgttcc cagctgttta gccgaaagct caggggtgat cttcacaaga
    16801 tagctggact gcctcgcacc aaacggcagc tctctgaacc tgctcaggcc tgctactttt
    16861 ctccttcaac gctgtgtatt tatctgttgt taatactcta tcactgtaag actgtgatgt
    16921 caagagaaaa attttatttt tttgtctgcc tttcccgcat agaaaaaaca catccacagt
    16981 agtcctgtcg gtaaagatta tattttttag acagttctgt ggagcgtttg tatccgtttt
    17041 tcttcttaaa atcagagtcc agataagata ccccgtattt ctctcccatt tcttccccaa
    17101 tttggttcag tcttgcagca tttttcagag ggctgatagt gagtgtcgta gtgaaataat
    17161 caaagtttcc ttcctttgcc agtcttgccg cctcctcaag acgcaaggaa aaacagatac
    17221 tgcacctttc tccgccctcc ttgtctccct catggccttt cacggcctca tagaacagtt
    17281 caggcctgta ttcccctgaa ataaaggaaa tcggatattt tgccggaagt tctcgaataa
    17341 ggcgttccac ttccatggtc ctctcctcat actcctcagg aggataaata ttcgggttgt
    17401 aataataaac tgtaatctta aaatattgag acaaatattc cagcacatag ctgctgcagg
    17461 gagcacaaca gctgtgaaga aacaatgtag gaataattcc cttcccctga tttttttcaa
    17521 tcagccgatc catttccttc tgaaagtttc tgttgttatt gcttttatnn nnnnnnnntt
    17581 tatttatatt tttatgaatt tcatttataa tttcgttcat cttctgcctc tcctcgaatc
    17641 tcctctgttt tttcgcatcc tgctgcctct tttatttcga tagtgctgta atttctatcg
    17701 aaacaaaaag actgccaaaa cttctttcag cagtcttttt tcgcccatgt taactttttc
    17761 atctaactaa acggccttct tatatctgag gccctgttgt cgtttttatg gtacgtgata
    17821 ttcaaacttc catgaaacag ccttgaaagc tgcaagtcag actccactac aggaagtccc
    17881 tgattctctt gcttctcaca gggtttctga gctttctgag cgccttagcc tcaatctgcc
    17941 tgatacgctc tctcgtcacg ttgaactcct tgcctacttc ttccagagtc ctaggatgtc
    18001 cgtcctccag tccaaagcgc agtacaataa cctggcgctc tctctccttc agatctccaa
    18061 gcagagcgtc aatgtgctct ctgagcatca cagactccac gtttccttca ggcgttacta
    18121 catttccgtc tgcaacgaaa tcgcctaaat tggaatcgtc ctcctcgcca atcggcgtct
    18181 ccagggaagc aggctctctg gcgatctgca tgatctccat caccttatcc tctgacatat
    18241 caagagctgc tgaaagttca gccactgacg gctcataacc cagctccaga gtcagcttcc
    18301 tctgcatctt ggacatcttg ttaatcgttt ctaccatatg caccggtaca cggattgttc
    18361 tcgcctgatc tgcaagtgct ctcgtcacag actggcggat ccaccaggtc gcatatgtac
    18421 tcagcttata tccttttgtg tagtcaaact tttctactcc tttaatcagg cccagatttc
    18481 cctcctgaac cagatccaga aagctcatgc ctcttccggt atagcgcttc gcaatactta
    18541 ctacaagcct taaattggcc tcaattaagc gttcctttgc agacacatcg ccctctgcct
    18601 ttctcttagc aaggcgcagc tcttcttcag cgctgagaag cggaactgta ccaatctcct
    18661 tcaggtacat gcggaccgga tcctctgtgc caattccctc cagaaggtca atggcatcca
    18721 ggtcgatctc ctcctcttcc ccgtttttca taaagtcgtc gtccacatca tcgagcatca
    18781 gcagatcatc gttgagtgca gtctcatcaa tcacttccgg aatcacatca atattattct
    18841 gttccagata gttatagatc tgctccatct gttccggtga caggttgtcg gcggcaaaaa
    18901 aatcattaat ctctgtaata tccagagcgt tctgctttgt ttttgccaga tcgacaagtt
    18961 tttttaattt ttctaaaaaa ttgtctctct ctttctccac gaattaacgt cctttcgcta
    19021 tcagaagctt tataaaaagt ttaccgactt tatattatat actaatcttc tacagatttc
    19081 aacaacattt ttaaaaacct gagccgggca gccagtctca tagaaagctt gcctgtccct
    19141 acctcttcac cacaatctct tccctcagat tttcaatgca gatttccttt actccgcctc
    19201 catattctcc gtccagcgtc caatccacga tttcttcact ttccattctc agattggagg
    19261 tgcggaacat atacacgcag tcattttccg catctttatt aatcaggcag cttacaatgc
    19321 tctgaatatc cttgggagtc ctcggctttc tcaccagcat aacctcaaac tctccgtcat
    19381 ttagagccac tctgggctgt accagccctt taaatcctcc gatgctgatc gtattagtca
    19441 ccattcccag aataaagtcc tcttccagct cctgatcgtc ccaaaaaaac ttcatacggt
    19501 aagatttcag tccagcgatc ctcttgactg cctccagcat ataggcctga tgccccagca
    19561 catttttcgt ctcctgcggc gtcttgtaag aaacctctgt gaaggctccg aatgcagcca
    19621 catacacgaa ataccgtccg tctccaaatt ttcccacatc aatggcaaaa ggacggcccg
    19681 caacggctat tgcagcggcc ctcagcatat ttttgggaag atccagactg gcggcaaaat
    19741 cattggtaga gccggctgga atatacccta gctgaggacg cttttccctg ctccacgcca
    19801 tcattccgga aaccacctcg ttcagcgttc catcgccgcc gctgcacacc agaagctcca
    19861 cgccgccgcc cttcttctcc acctgttttt gggcatcgcc ggcgctctga gttacatgaa
    19921 ccgtcacctc atagcccgcc ttcacgaata aatccaaaat atcaagaagc tttgttctaa
    19981 gccgctccct tcctgatctg ggattgaaaa taaacagcat tttcttcatc tgtcctacgc
    20041 tcctctgtct gctccgcaaa tatgcccatt cccgctctgt caaggcagta tgtgcttagt
    20101 attcctcttt aaaagcgccg tatacgcctg aaatgcgttg ggcaaaggat atgtttcaaa
    20161 aatctcttcc acccgcttca tgggatactg atgcggcagt tctcttttta tcataacacg
    20221 aaagcctgtc atatgccact ctacatgaga aaagatatgg accgcctcag gcaaaggctc
    20281 aatcgccaga atgtcctccc ggccaatggc aagagcgtcc ggaatctcct cctccttcag
    20341 atgccccggc agattcggaa attcatacag ggacgccaaa agccccttgg cgcttctctt
    20401 tctgatggca gccttatcct cgtactctat gataaaaact gttttttcct ctctgcgcct
    20461 ctcctttttt cctgccttta caggaatttc tcctgtcgtc tggcggcgcc ttgccaggca
    20521 cagcgtcgaa catggacact ggctgcagag aggctttcca gacggaatgc agacaatggc
    20581 tcccagctct atgagggcct gattaaactc tccgggaagc tcttttggaa tgaccgctct
    20641 cagttcattt tccatctttc tttttaccga ctgctttcca atatcctctc tgctctcaaa
    20701 cagcctggac agaacccgga gcacattgcc atcaactgcc ggttcaggaa ttccaaaggc
    20761 gatggaggcg acagcgccag ccgtatagct cccaattcca ggcagggaga gaaggctttc
    20821 ataggaagcc ggaagctgtc ctccatactc gtccatacag actctggccg ccttctgcag
    20881 atttctggct ctgttgtaat atccaagacc ttcccagagt tttaagagcg tctcctcctc
    20941 cacagaagct aaagccttta catccggaag ggcctccata aatctggcga aatacggctt
    21001 taccgcctcc actctcgtct gctggagcat aatctctgaa atccacaccc ggtaagattc
    21061 cggctgttct ctccagggca ggatccggcg gtttttgtga taccaggaaa gaagcggctc
    21121 tctcactgcc agaagccgct catttctgtc catcgtctgg ttttctgctt ctacctgcat
    21181 caggctgccg tactggcgct ttatccagct gttttccatg tagtctttcc tctgctttct
    21241 caatttctta cgcccgctgc cgggaagcct ttaaacgttc ctgccgccta aacatatccg
    21301 taaattcccc ttacagaaac ctctccggaa ataactgttt ttacggtctt atcatccatc
    21361 tccaccagaa gctcgccctg gctgttaatc ccctgagctg tgccgctgta ctctccagcc
    21421 ggatccagca cccggactgt ccggccgcag ttagccagct ttccattgta ctcctccaga
    21481 agtccgctca tatctgccgt cttcataaaa acgccgtagt attcttcaaa agcttccatt
    21541 actgcgctga tcagcacgct tctcctgatc tttttccctg attctgtgta gatagatgca
    21601 gctacctgac ggatttcctc tggaaactgc tccatattga cattgatccc aatccctgta
    21661 accacatagt taatacagtc gggatctgcg ctcatttctg taagaattcc gcaaaccttc
    21721 ctgccattta tcacaatatc attaggccac ttaataagcg gcttcacctg agcgcactgc
    21781 tcaatccccc tggctgcagc cagagcagct accagagtca gcatggaagc gtgaaccgga
    21841 gccatatccg gacgcaggac caggctcata aaaattcctg ttccacctgg ggaatcccag
    21901 gttcttcccc gcctgccctt tccgcctgtc tgacgttcag ctaccgtaag ggttccatga
    21961 ggcgcgccgt tttctgctgc cttcttggcc tctgtgttgg tggaatctgt ctcgtcaaaa
    22021 tagagcacct ctttccccgc ccactggccc ttcatgctgc ttaaaatctc ttccctgctc
    22081 agaatatcct cggccgtctt cagcctgtat cctctgttcc gcaccgcctc aatctcatag
    22141 ccttcggctt ccagctgttt catcaccttc cagacggctg ttctcgacac gtggaactgc
    22201 ccgcagagct cctgcccgga aatatatccg tccgcttctt ttaaatatct aagaatttct
    22261 gtcttcatgt tatctttacc cccaaagaat cgatgcggcg ctgaacagag ccatgagaag
    22321 cagcgctgca gccagcccta aaaacaggaa ccctgtccgg cgtttttttg ctctcctgcc
    22381 gcctgacgtg ctcatcctgt ccatgccgtt aaccagatta atccctgcag ccatcaaaaa
    22441 aatgacagga aacaaaagcc tgtacctgtc gggattgata aaaaccagaa tggaaaaaat
    22501 tacaatccca agccctgccg caatatcggc cgtctccttc tttaacctgg acgccctgtt
    22561 ttttctctgt ccttctgtca tcagcatctg ttctcctaac gcctctctct gggccttctc
    22621 tttctcagta atctctttta ttttaaccga atccagcctg attgtaaata aaggatgtca
    22681 gaaaagccgc tgacaaagat gtacagcggc tcttcctgct tccctcataa attttataaa
    22741 acagtctgct atttggcagc ttcgtccttc tctccaatct ctgccagaga ttttacgaga
    22801 cctgcgattc cctgaatttc tgacggaata ataatctttg tggcttttcc atcggcagcc
    22861 ttggcaaagg cctccaggct cttcagctgg agaaccgcat tgtccgctcc tgcctccttg
    22921 ataaagcgga taccgtcggc attggcctgc tgcaccttta agatggcttc tgcgcggccc
    22981 tccgcctcct tgatcatctt ctgtttttca gcttccgccc ttaaaatagc ggcctccttc
    23041 tcggcctctg cctccagaat cgcagacgcc ttctgtccct ctgccaccag gacggtagac
    23101 tttttctctc cctctgcgcg gaggatggcc tctcttcgct cacgctctgc cttcatctgc
    23161 ttctccatgg cgtcctggat cgctgccgga ggaatgatat tctttaactc tacacggttt
    23221 accttaattc cccatggatc cgtagctaca tcgagagcgg ctctcatctt cgtgttaatc
    23281 gtctctctgg aggttaatgt ctgatcgagc tccagatctc cgatgatatt tctcagcgtg
    23341 gtagccgtca gattctcaat cgccataatg gggttttcca ctccataggc aaacagcttc
    23401 ggatcggtaa tctggaaaaa caccaccgtg tcgatcttca tggtaacatt atccttggtg
    23461 attaccggct gaggcgggaa atcaactacc tgttccttta aaataattct cttggccaca
    23521 cggtcaacga aaggcatctt aaaatgcacg cctacagacc aggtgtccag ataagccccc
    23581 agtctctcca cgacaatcgc ctgagcctga ggaacgatct taatgcagga cagaagcact
    23641 aaaagcgcca ccactgcaag cacgacaaac aatatgaaca tactacttct cctcccttat
    23701 ttttcttacg atcagcttaa caccctgaat ttccataatc tcggccagag cgccggcttc
    23761 aatcaccgag ccgtctgcgg aacgcgcagt ccactcgcgt ccgtccagca cagcggttcc
    23821 tgccgccctg tcattatcca cgtcctctgt aatcacagcc ttctttccaa tcagctcgtc
    23881 cacgtttgtc ttcactgtct ttggattgac ataccgcagc gccaccggcc ttgtaaagaa
    23941 gaacagcaca caggataccg caaaaaacgc cgccagctgg ccatattttc ccactcctgc
    24001 cagagtaaga aaaaacgaaa ccagagctcc tatggcaaac catatggtac acagcgtcat
    24061 agtagcggcc tcaattccta tcaataccac gaaagctgtc agccagataa tccgctccaa
    24121 atctgctccc cctttctccg ctctgttttt ctgtatctat ctgttattat atacttcttt
    24181 ccgactttat tcaatcaatg tcagaaaatt gtaagttttt taatcatttc gtctctgcct
    24241 tgccgtctca tacatcagaa tcgaggcagc tacggcggcg ttgagcgatt ccacctttcc
    24301 aagcattgga attttaatgt agcagtcagc catatcggcc gtttcagcac tcaatccgtt
    24361 ggcctcgttg ccgatgagaa agcccgtatt gcctgtgtaa tcctcctggt cgtagcttct
    24421 ctcccccttc agatgggctg caaacaggcg gacacctgcc ttcttcacct gtctgattgt
    24481 ttcctgcaga tcgtctgtat agagaaacgg tacccggtaa atagagccca tggtggaacg
    24541 gattaccttg ggattgtaaa tgtctgccgt cgtgcggttc ataataacgc ctgtgattcc
    24601 ggcgccctcc ccggctctta aaatggttcc cagatttccc ggatcctgga tggtctccag
    24661 aacagccaga tgcatctggt ttccccccag aatatcggaa agctggtagg aaaactggcg
    24721 gcacagagcc aaaatcccct ggggcgtctg ggtgtccgac atggcccgca ttacctcatc
    24781 cgtcactgtc tcgtaccggc agccggacag aagcgcttct gctctctccc cctgctgcct
    24841 taaaaagctc tccgacacat aaacccggtc cagccgctct ctgggcagct cggaaaacat
    24901 cttctccccc tctaccagga acaggccgct ctcctttctg gccttggctt tcttggccag
    24961 cgcgcccacc tgctttacct gtgaatttga cgtgctggta atcatgataa cgcctccagt
    25021 tcctccagcc acaggcggct gactgcgtcg ctgggcattc tcagatcgcc cctcggggaa
    25081 acagcggcgg atcctacttt cggtccgtcc ggaaggcagg aacgcttaaa ctgctggttg
    25141 aaaaatcttc tgtagaatac cttcagccac ttgagaattg tctccctgtc atacgttccc
    25201 tggaaggcgt acagggccag acggtaaatt tttcccggct gatagccgta tcttaacaca
    25261 tagtagagga agaaatcgtg aagctcatag gggcccacca gatcctccgt cttctgggca
    25321 atggttccgt tgtcctccgg aggaagcagc tcagggctta ccggagtatc gagaatatca
    25381 agcagcaccg ccttcagctc ctcctccccg caggtatccg catagtagcg gaccagatgg
    25441 cggaccagag tcttcggcac agaggcgttc accccgtaca ttgacatatg gtcgccatta
    25501 taggtagccc atccgagagc cagctccgac atatctcccg ttccgattac catgcctccc
    25561 gtctgattgg caatatccat gagaacctgg gttctctctc tggcctgaga attttcgtag
    25621 gtcacatcgt ggacggacgg atcgtggtta atgtcgcgga aatggatgtt tacagcgtcc
    25681 ttaatgtcca cctccagaag cgtggctccc agcttcttcg tcagcaggca ggcgttatgg
    25741 taggttctgt ctgtggttcc aaagcagggc atggtgacag aataaatctt ttcctttgga
    25801 aggccggcca tctcgaaggc cttcactgtc accagaagag ccagggtgga gtcaagaccg
    25861 cctgaaattc ccaccaccgc gttctggcag tgagtgtgaa ccaaacgctt tttcagtccc
    25921 atagcctgga tcatcaggat ctcctcacac cgtttcgccc gctcggcgtc actgcccggc
    25981 acaaacggag acggatctac aaaccgttcc agatgggaat actctttttc ctgctccgcc
    26041 tcctcatcct ccagctcaaa ttctataatc tcataatctg cctgtccctc cgtctggtag
    26101 gtggtcattc ttcttctctc gcactccaga cgctccaggt caatgtcgca gacaatcgtc
    26161 tcgctgcaga aacgtctgga ctcctttaag actgtgccgt tttccgcaat aatattctgt
    26221 cctccgaaca ctaaatcctg ggtggactct ccctctcccg cgttggcgta gacgtaagcg
    26281 cataaaagtc tggctgactg tcctgaaatc agacttctcc tgtaatcagc ctttcccgta
    26341 gtctcatcgc tggcagagca gttgacaatc acggtagcgc ctgcggccgc atgagcgctg
    26401 ctgggcggat ttaataccca cacatcctcg cacacctcag ctcctaccac aagattttct
    26461 gcatttttgc aggcgaacag aagctttgtt cccataggaa ccttctggcc gtcaaactct
    26521 accgtcacat ttccaaactc ccagggatta aaatgacggc gttcgtagaa ctctccataa
    26581 ttaggaatcc acagcttcgg aacgatgcct aacagccttc cgtcctgaat cgccgccgct
    26641 gtattgtaaa gcttgtgatt gtactcccag ggaagccctg caaataccag catatcgctt
    26701 cccttagtga agtctgccaa cgccttcagc tcacgcttca ctgccgttaa aagagacttc
    26761 tgcagaaaca aatcgccgca ggtgtaggca gtcaggcaca gctctggaaa aaccataatc
    26821 ttgactccgt tcttccttcc ctcctgaatc ttcctgcaga tctcttcccg gttaaactgc
    26881 acatctgcta cttttacctc cggcgtggac gcggccacgc gtaaaaaacc atctctcata
    26941 gtctgtctcc ttgttgtatg attcattgat ttactgggga acctgtctgt cttcctctgt
    27001 tggttttcag tataccatta ctcttacaaa ttgtcatcta ttcctgccag acttcggatc
    27061 acgcagcctg caagcatcat gccggcggcg ggaggaacga aggaaacgct gcccggcacc
    27121 gccctctttc tgggagccgt tccctctatt ttctccggct cctccagccc ggattcacta
    27181 cttttctctg tctgctccct gggctttatg ggagtttccc tggaataaag caccttcagc
    27241 cgctcaattc ccctcttttt cagctccctg cgcatcacac ggcacagcgg gcacacggag
    27301 gtctccgaaa tatctgcgat ctgaaacagc tctggatgaa gcttattccc tgttcccatg
    27361 gaggcgataa ggggaatgcc gtgctctttt gcatattctg ccagagccag ctttgcggcc
    27421 accgtatcaa tggcgtccac tatataatcg atcgttccct ccacttctga aagaagcttt
    27481 tccagatttt caggaagcac aaaggcttca atggtaataa cctctgtctc cggactgatc
    27541 tgacggataa tctcctccat cacctttgtc ttaaatgttc caatggtctc ctggaacgcc
    27601 acgctctggc ggttgatatt gcttctggag actacgtcgc tgtccactaa aatcagtctt
    27661 cccactccgc ttctggccag ggcctcaata cagtgggaac ccactcctcc cactccgaac
    27721 acagccactg tgctggttcc aagccttgca agcccctctg atcccagaag gagtcccgtt
    27781 ctctcaaatt cttccattct ttctgtcttc atcatcaaat aaagggatgt atcccacatc
    27841 cctctccctc ctgtttttaa ttaaataaag aaaaaaagaa ccgcttctcc ccctagaaaa
    27901 cggctcttcc cggtcacgtt catcaaccga tacattaaat agttttgctt tgttaaatat
    27961 agcactttta tccccttgtg tcaactttgt ttttgtcatt ttgcacaatt tttcacaatc
    28021 cagccgccag atttctgatt cgtcccgcct gttcgccctg cctgaatatg taagggcaaa
    28081 agtccttatt gaagcgctta tatttttcat ccatctggga atactgtaga gaaaccagat
    28141 tttgagagga gcttttttat cttatggaaa tttctaataa attggacgct aatctgcgcc
    28201 attttcatca gcttctgcga gtcaacgaaa actttgacgt agtgtaccgg gtcattcaga
    28261 tcggagggcg ggacgcctgc gtttattttg tagacggctt tgccaaggac gataccctgc
    28321 ttcggattct ccagggcttt acctccctaa agcctgacgc ggttccccag acagcccatg
    28381 agttttccaa gctgtttatt ccctatggag aggtggacct tttgactgac gacgccgaaa
    28441 tcgcggtcca ggtcctgtcc ggcgttccct gcctttttgt ggacggatac agcaaatgct
    28501 ttgccatcga ctgccgcacc tatccggcca gaggcgtggc tgagcctgac aaggataagg
    28561 ttctgcgcgg ttccagagac ggctttgtgg aaactctggt atttaatacc gccctgatac
    28621 gccgccgcat ccgggatcct cagatgacca tagaagtaat gcaggccggc agcaaatccc
    28681 acacagacat tgccctctgc tacatggaag gacgggtgga tcaggatctt ttaagcacca
    28741 tcaaaaagcg gattgaacgc cttcatgtgg acgcgcttac catgaaccag gaaagcctgg
    28801 cagagtgtat ttatcctcac aaatggttta acccttttcc aaaattccgt ttttctgagc
    28861 ggcctgacac agctgctgcc tctattctgg agggaaacct tgtcattctg gtggacaact
    28921 cgcctgctgc catgattctt ccctcctcga tttttgatat tgtggaggaa gcggacgact
    28981 actatttccc gcctctgacc ggaacctatc tgcgcgtttc cagaatggtg atctcatttc
    29041 tcaccctgtt tctgactcct gtgtggcttc tgtttatgca gaacccagac tggattccca
    29101 gctggctgga atttatccgg ctgtccgacg agattcatgt agcgctgatt tttcagctgc
    29161 tcattctgga atttgccatt gacggactgc ggctggctgc agtcaacacg cccagcatgc
    29221 tgaccactcc tctgagtgtg atcgcaggca ttgtgctggg agagtattct gtgaaatccg
    29281 gctggttcaa cagcgaaacc atgctgtaca tggcctttgt cacggtggcc aactattccc
    29341 aggccagcta tgagctgggc tatgctctga aattcatgcg cgtctttctg ctgattataa
    29401 cggcattttt caatctgtgg ggattcgttc tgggcaccgt actctgcttc ctcgccctgg
    29461 tctttaataa gaccatcgcc ggaaaaagct acatttatcc cctgattccc ttcagcttct
    29521 ctgagctgaa aaagcggctg atccgcacgc gcctccccca tgcagacggg cagggagagg
    29581 aagaccgtta aaaaagcttt actgcagctg catacccagg ctctgtttca ggcgaagcag
    29641 agcctcttta tagtgttcag ccggaacaga ggcacaggac agaagaatgc ggcggattgg
    29701 caggccgatg gcagtctctg tagaatccgg cgaagaaccc cttgaaagaa acgctctgtt
    29761 ccactctttc tcgtcaactg tcctcacccc tacgcctgct tcctctgccc tctgtctgat
    29821 ttcttctcca gaaagttctg tctgaagctc tgccagaacc aggaagcccg cttctcctgg
    29881 atatgctttt gccttttctc caaacagttc ctgaatatcc tcacacaaaa gttttgcctt
    29941 ttgaaggtaa agccgcctgg attttcttat ctgagcttcc agatggccgt ccctgatgaa
    30001 ctggcacagt gcaatctgct ctgccttgga ggccgtctgg ttataaaact ctcctcttct
    30061 ctgataaacg ggaagcaatt ctggcggcag caccataaag ctcatacgga tggacgggag
    30121 aagcattctg gagaaggttc ccatataaac gactcccttt ccgcctgaca gtccctgaag
    30181 agatggggcc ggccgattat agtagctgaa ttcgctgtta taatcatcct caatcaaaag
    30241 cagattcttt tccatggccg tctttatcag cttcgtccgc tctccgattc ccatgacctc
    30301 tccccagctg gtaatctggg atggagtgag ataaaaaata ctgtctgccg gcagctcctc
    30361 ccggccgctt tccatccccg acaccaaaaa gccataatct tcaaacactg tgcgcccctg
    30421 gtggaagctc tcattgttca tcagtacctg acgcctttcc cggatcatgg gacataagat
    30481 atgcagaaga ctctggactc ccgctcccac cacgatctgt tccggcgtgc agactacatt
    30541 tctgtgcctt ctcaaatacc gcgacagctc ttctctcagt tctccctcac cctgaggctc
    30601 tccataagac aggagacgct catcctggcg cagagcgctc ttcacatatc ttctccagac
    30661 ctcaaaccgg aagctttccc gatccaccct ggaggaggag aagtcaaata acagctcttt
    30721 tttctttttc cttgtctgct gccggctttc tgcccgcctg gcctgtccta aatttgtcac
    30781 ataatatccg ctctgcggct ttgccgcaat atatccctcc gctgccagca tcaaatacgc
    30841 ggtctccacc gttgtcctgg aaagattaag ctgtattgag caggttctga tagagggcag
    30901 ttttgctcct gcctccagtt ttttctcctc tatcaggctg cggtaatact ggtagactct
    30961 catatatctg agggttccct cgtcatccag atatctggaa ctgtctctct ccatgcttct
    31021 cctcctgtct cggcatgttc tcttttagat gaatctaaga taaaatctct gccggaataa
    31081 acttccggca gagacacttg tttcatctac tctgtaaaat ttttaaatcc aagtccaaac
    31141 acctctgacg tatctgtcac cattacaaac gcattgggat ctgcttcata tacaattttc
    31201 tttaaacggc tgaactgaga ttttctgact gtgcagagaa gcacgtttgt atcctgctta
    31261 ctgtacattc ccctggccgg aatcagcgtt gccgtccgat ccagctctcc aatcacctta
    31321 tcagaaatat cgtctggatt ggatgtgata atggtagcca tgctccccgc ttctccgccg
    31381 taaataattg tatcaataac tttcgtctgt acataaagcg caatcattcc gaacagagcc
    31441 gcctcaatat ttccaaacac aaaaatagat acggccagaa taatgccgtc cacaatcatg
    31501 agcgcccggc caatggatat atggggacgt ttcttctgaa gcacatatcc caggatatcc
    31561 gtgcctccag tggtacttcc cgctataaag atgagggcca ttcccgcgcc tacaataacg
    31621 cctccataaa gactgcacaa aagccgatct cccgaataag ccggtactat aaacggcacc
    31681 acaaaatcca gaaccaatga gcagagcgtc gtagttactg ctgtggatat ggcgaatttc
    31741 ttactgaggt aaaaccaggc cagcgctaaa agcggcacat tcagcagaag tgtcagaatt
    31801 cctactggaa gccctgtcac ataattaacc attaaagcca cacctgtagc tcctcctggc
    31861 gcaatattgg caggtatcac aaaaacgtag gttcctattc catatatcaa tgagcctaaa
    31921 agcagaaggc tgatatcctt ccacagctct ctcccattta gtttctccat aaaatccccc
    31981 tccctttccg ccatcttctc ccgcgataaa acaggtgatg ctaaaaagca tcacctgcgt
    32041 attttgcaaa ctgcgattat tatgtcagaa gtcccttctt ttactgctca atgctgtagt
    32101 tgggcgcctc ttttgtaatg tgaatatcat gcggatggct ttccttcagg gaagcggcgg
    32161 aaatcttaac aaattttcct gtctcctgaa gagtagggat attggaagct ccgcagtagc
    32221 ccattccggc gcgcaggccg cccagaagct ggaatactgt atcctccacc attcccttat
    32281 aagcgacacg gccttccact ccctcaggaa ccagcttttt ggcatctgtc tggaagtagc
    32341 gatccttgct gccgttttcc atggctgcaa tcgatcccat gccgcggtat accttatact
    32401 ttcttccctg ataaagctcg aaagttcccg ggctctcgtc gcatcctgca aagagggaac
    32461 ccatcatgca cacgcttccg cctgctgcaa tcgcctttgt aatatctccg gaatatttga
    32521 ttcctccatc tgcaataaca ggaattccat attcctttgc cactgcatag cagtccataa
    32581 ttgctgaaat ctgcggcacg ccgattcccg caaccacacg tgtcgtacag atagagccag
    32641 gtccgatacc aaccttaact gcgtcaactc cagcctcaat taaagctttt gccgcctctc
    32701 cagttgccac gtttccagcg atcacctgta catccggata ggcttccttg atcatcttca
    32761 cgcagtgaat tacgtttgca gaatgaccgt gggcagaatc taaaacaacg acatcaacct
    32821 ttgcattcac aagggcttcc acacgctcca gcacatttgc tgtaatgcct actgcggctc
    32881 cgcacagaag tcttccctgg gcgtccttgg cagacagagg atatttaatc tgcttttcaa
    32941 tatccttaat tgtgatcaga ccctttaaat taaagtcgtc atctacaatc ggaagtttct
    33001 ccactctggc cttggcaaga attttcttcg cctcaagcat tgtagttcct tccttagctg
    33061 taaccagatt ttcagaagtc atacactcct taatcttctt ggaataatcc tcctcaaact
    33121 tcagatcgcg gtttgtgatg attcctacca gctttcttcc ctctgtaatc ggaacaccag
    33181 aaatacggaa ttttcccatc agttcatctg catcttttaa tgtatgctct ggggataaat
    33241 agaatggatc tgtgatgact ccgttttcag aacgctttac cttgtccacc tcttctgcct
    33301 gttccttgat ggacatgttc ttatggatga taccaatacc gccctgtctt gccatagcga
    33361 tcgccatcct gtgctctgtt acagtatcca tgcccgcact catcagcgga atattgagct
    33421 taattttttt tgtcaggtat gtgctgagat caacctgatt cggaataacc tctgaatagg
    33481 ccggcaccag aaggacatca tcaaatgtaa tgccatcacc gataattgta cccattaatt
    33541 tttcctcact ttcgtattag ctttattaat aagtttaatt aataacatct ttgtgatagt
    33601 aatttattgt atcaatttta aaataagatg tcaacacagg gtgaggaaaa tttttgtctc
    33661 ggcttgtctg ctttgttcct gtatttctat ttttcatcca ttcctctctg cctggatgat
    33721 cagtctttgt tttcttccat ggcaggtaga taatgtcagc cgcgtctttc ccaaagcgcc
    33781 tccgtccgat tcataggggc ttttatctct gctgtccgcc aggtagacct tctgaatctg
    33841 atactctgtc cattctttct caacgcagag ataaattgtt ttatttttct ttaaaaattc
    33901 ctcctctctg tattttttca ggcttccaaa catttctcca gacttcatat tatgtccgta
    33961 aatcactgta ttctttgaag acaacggagg ataggaagcc tcgaaaaaaa gacatccgca
    34021 tggatttttc tgtccgtcaa aggttctgtc cagatattca ttattattct caggatacac
    34081 aaccggatag ctgacaggcg ttccgggaat ataaatccat cccgcatagt caggattcat
    34141 ctgcaggagc ctggtttcgt ctagaagagg gaccggaatg tccgtttcct gttcctcccc
    34201 gtcttcgcgc tcctccaccc cggcaatttt cctggtaagc tggtatgccg cctttcccct
    34261 ctgatcacgg cagtattttc ctgcaagcaa agctgcgctc aaaagcataa ctacaagcag
    34321 tatggcggca gctgcggctg cgcacatatg tttcagtctg tttccaatgc cgctgttttt
    34381 ttctttcatc tatccctttt taagagtcct tcctccgttt tctgcggctg cataaaatca
    34441 aaagtcctgc tgctgagcct gcaaacagcg cctctaaaag cttcactgga aaatcatctc
    34501 ctgttttggc agggagaatt tccgtcccct ggccccgtat gcttaacgtg ccgtttccat
    34561 ataatgtttc gtcataggat accgtaatct ttcctttcat cttttccttc ttctgattta
    34621 ccgcgataaa tacatagctg ttttctgcat cctggcaaaa catatggtcc cctccgagaa
    34681 gctctgcatc tcctttggcc ggaattcgga ttttgtatga tttatttaga gcttcatatc
    34741 cgtccggcgc tgccgtctcc ctgacaatga ctgtctgagg cttctcaagc agaagtttaa
    34801 attctgtgcc atctgcctct gtttccaaag caagctcttt cccattttca tctgtcacag
    34861 tgaaagctgc gcctgaaaga ggcattccgg cttcgtctgt cttttttatt ctgatcacaa
    34921 aatcgtttcc tccgcctcct ctctttttcc tgttttcagc tgtcactgtt gtggtctctc
    34981 ccagacggct gaccgtaaat ttctggtcct ccataagcgc ataaccggct ggcgcctttc
    35041 gttcatggag aatatacgtt tttcctgcct ccagtttctg atacagctta tggggctctc
    35101 cttctgaaat ccaccgctcg atgctgtttc ctttttcatc caggatttcc agttcagctc
    35161 ccgcaagagg cctcttactg ctgccgtcaa tttttaaaat ctctgttttt gtcacatcat
    35221 cccgcatctc tacccggttg acgcttccat catggctgac cgtaaatttt atctcctctg
    35281 cataagaata accaggagcc ggttttatct ccgtcaaaat gtatgttcga tctgcctcca
    35341 gttttcctgt aatctcatgg ggcttcgttc ctgaaatcca ccgttcaatc tccttcccat
    35401 cttctgttgc cagtctcatc tcacagcctg aaatctcctc ttctcctgtt atatcttttt
    35461 tcgaaatgac agcttttgta ggtttgtctt ccattactac aatatcgatt gctccatctg
    35521 tgctgaccgt aaattttacg tcctccgcat agccgtatcc aggcgccggt tttacctcat
    35581 gaagccagta agtctttcct gcggtcagct tacgctccag aaacgcaaag gtttctcctg
    35641 ttgtaaaaat catctccctt ccttcaaaca aagccggcgt tttgtcctcg tttaaaatct
    35701 gcaggatagc tcccttcact ggcatctcct ttgcatcaga agacaacgcc ttctgtattt
    35761 ctttgtccaa tccctgatat acgtttttat aaattctgac ttttgtcgta tcatccctca
    35821 tttccacata gttcacactt ccatctttat ttaccgtaaa cgtaatatcc tttgccaggg
    35881 catagccgtc agccggtatg gtctctctca aaatataggt ttctccggca gtcagctttc
    35941 cctgtatttt gtggggagtc cgttctgaaa tccactcctc ctgtacaatt ccgttcctgt
    36001 caagcacctg caaatgcgct cccggcagtt cctcctggtt agtaatatcc ttttttgata
    36061 tgacaatctg agtctgacga tcctccatac agagaatctc cggcgcaccg gacggattca
    36121 gcgtaaacgt gatatccatg gcataaccat atcccttcgg agcttctttc tctttcagac
    36181 gatatgtgcg gccaggaagc agtccctctg ctgaaaatgc atcttctcca gacgtccact
    36241 ggcactccag aatctcttct cccttctcca gacgatacag ctgcaaaact gcgccctcta
    36301 ccgcttttcc tgtaagcaga tcggttttct gaacctccag ctctgtctgt ttatcatatc
    36361 cccccacaac cgaaatatcc gcctgatcgt tcagcgtaaa agataggcag ctgctgacct
    36421 ctgtttgatc acctgaataa atggtagttt ctgtaatcag gtaggtttct ccctttgaaa
    36481 agacagctct ctctgacgta tcttctgtat ttctggtaaa ccatgccgcc gttccgtcct
    36541 cagaaatcac gccctcggtc tcatgagact ccgtttttac gccattctcc ttccggctca
    36601 cctgataggt acatcctttc agaacaggat caattgtgac gaattcattc ccagccagct
    36661 cgatcgtatc tccgcttttc agcgttcctt ctctgctgcc tgtataagaa taagttcctg
    36721 ccagctcatc tcccttttga ttccacagtt ggacggtaaa aagagaggtt tctttttctg
    36781 tctgttcagc ggctgaacct gtcagtccat tgtaaaccgt gagacagtgt tcctgcaaaa
    36841 caggaaccgt ctttctgcct tttaattgtt tttctttccc cagttccagt tctgcagcaa
    36901 tctctgccga ttctcctgaa accgtctctg ctataaattt tacgcttccc tgactcagag
    36961 gagccgcctg tctgatcttc cagacaagat tcctttttcc tccatttcca ctctcctctg
    37021 tcccttctcc ggcgtcaaaa acttctaaat tatcagaaat ttcagccctg attacaatat
    37081 cctgcgcttt gcgagacgtg ttatgccagg taataattcc ttctgccggc tgccctcttt
    37141 ttatgggagc tccagcctgc gcccccttat ttttgagaat tatttgagga ttttcaggat
    37201 ttaccctatt ttgaatcaca gtttccatct gttctggcag aggttcaaac tctgtgatag
    37261 atactccatc ctgatcggtc actgcaattc tcgttcccac ggctcttctt ccttgaaata
    37321 caaagaaacc atcttcatca aaatgaaccc tctttgtaat tcttctcgaa atgcagctct
    37381 ttccatctga gtaaaaggta cgctcctcaa aggtatacag ctcgttttcc gtcaatccgt
    37441 cctttcggct cagctggtgc gatcccccag tctccgctat ggtcagaata tcccttcctt
    37501 cttcatcgaa aaccgtaagc tctgttctga cagctgttct tcccctgaac gcgatgctgt
    37561 caatggaatc gctgtctgaa ttttcggctg tctcttttct gtaatgtacc cggacagcag
    37621 aaagactgtt ggaaatggaa gatattcccc ttccgtcttc ctttaaggta aagagaaccg
    37681 gttccatcag cgcatatcct tccggagctt tcttctctgc cagaacataa ctgcatcctg
    37741 ctgtcagccc tgtaatcagg tgtctcttct cctctgatga agtaatccac tctgttacca
    37801 aatcttcttc tgtgtaagta tactccccct tatcgtttat ctcagaaatc cggtagactg
    37861 ccatgcaggc tccctccaca aatattcctt ctgttccgga atctcccagt ccttccagtt
    37921 ctctcttttc cagataaatt ttcgtaacgt catttttcac gttctgttca tgaatcacag
    37981 tatggagcgt tccatcctca cagtaaccgc cttctccatt ttcgaaggta aaggtataaa
    38041 tctgcggatt agcggcaaat ccttctggag ggagaatctc tttcagcctg tattgatacg
    38101 gttcaatgtt tccattttcc ctgtcaatcc ttcccacagg cagttccatg acatgaacgg
    38161 ttccgttgat atctgacacc ttcctcggaa atccagatac catccggcct ttttcgtcat
    38221 aagcggacag ttcaaagaca acgccctgca gagaattttc tttctgatct gttttatgta
    38281 ctatcagttc cccttttata ggcttattga acatcgtctc tatctgtact gtttcgttct
    38341 tcgttccact gtagtaaaat tttacaggaa cagccgcctg gtagtaggcg ggagctttct
    38401 gttccgtcag gtagtagtat ccttctgaca ggtgaagcag agtgtgaggc ttcaagtctc
    38461 cctcggcaaa gccctctgga atcagtccgt ttatgaaatc cttctccgta tatactccat
    38521 ctgttcctga aatccaggaa tcaatcagat aggactctgt ctgattcagc attccatgtt
    38581 catctgcctt gtagaggaca agttctgcgc ctgccagctc tttcccagtg acagaggagc
    38641 gtttggaaac tgccagcgca tttttctcat tgaaaatctc atgctgctga atttcatgtt
    38701 cttctcccac cttcacaaga attggatccg cctttataaa gccttccggc gcttttgtct
    38761 cttccagcac ataggcggtt ccagacggaa gatagtcgat tctcctgccg ccgccctctg
    38821 acagccaggc atttgcatac ggtcccacat gaggaagagc gcagtaatca aatttataat
    38881 gatattcaaa gctgcttccg ttatatctga tatccgcaag aaccgttttc cctgtttccg
    38941 ctacccgcag gaacagcttc gcagcttccg gatatttctg cggttttcct ccctccagag
    39001 acacatccag actctctatt ttctccacag acgctctcct ggaaatcacc catttcaaag
    39061 ccagctgtcc ttcttttcgc gcctcgtagg cagctttaaa gcccgctctc tcctcgaggc
    39121 tcatggacag tggaaacgta accgtctctt ccccggtctc ctcgtttttt cctgtgatca
    39181 cgcggcttcc gtcttctaat atccacaccc gtgaattctt tgattcccgc tgcgccctgc
    39241 gttctgcgct ccatgagaat ccgcttccca ttacgccgta ggtttcatac atgttctgaa
    39301 gctccagggt aaagcctgtc tgccccttca ttcctcctgc gttgggataa ttcttcagat
    39361 caatggtatc tgtataatct gtagcgtcat ctgtgatcca ggaatctatt ttctttgaat
    39421 catctggcac cggatttcca tttttgtcat ataccaccgc tccattttcg tctgtctctg
    39481 cctcatagag cgtaaactcc gcgcctggca gaagctgctt ttttgtcccg tccttcctgt
    39541 atttataaaa ggctgtcttg gtatgatcat tatacagcct gaaattctga agatccggcg
    39601 tatgctccac ccatatctct tttggctgtg ccctgagaaa tccaggaggc gcgctcagtt
    39661 cttccaggat ataggggccg gctggaattc cctccacata atggggaata ctgcctgtgc
    39721 gccagagcat ctcctgatac tctctggatc ctgtccggct gtttgtcgtc tcaaaacgga
    39781 agggaacatc tgaaattttt tccagtctcc agccgtccgg ctcagaggga tcggatacct
    39841 tctttgccgg atacagagcc agttcggcgc cttccatctg cctattggta aagcagaagg
    39901 tttcttcccc acttccctcc tgaccgtcta ttttttcaaa atatcccttg gtcgtatcgt
    39961 cccagatgct gacacttttt actgtttcct cttcctctac cgtcactccg acaggaaatg
    40021 ctttcgtgta tccgcttcct gatggtactt ccagctcttc tacaatgtag gttcctgccg
    40081 gaagcctctt aagaagatcc ggctgtcctt ctgtcagctc ttcttcaaag ggatcattgg
    40141 gggttttatc tgaagaaatc caggagtttt ccaaaagata gctttcaccc aggcggtggt
    40201 acagccgatc ctgtatttga tgttcagcat ctgcctttcc atcaaacagc ttgtcatggc
    40261 cgtccaaagc ataggctcct ctgttgtatt cctccagatt gtcagaattt ttgtatctta
    40321 caaaatcgcc gtttctgtca tacagctctg tccccttgtc ataacaggaa tcgcttctct
    40381 gataatagag caccagacca tgttcatcat aaactggatc cataaagttt aaaagcttcc
    40441 cgttatttaa gtcaaacagc ggttcccggt tcatgttctg gcctttttta ttctgtacca
    40501 ccgtctgctc cttatggctc tcttcctggg aaccccaggt tccattaaca aatcctgttt
    40561 ccgtatggct gtactgcggt ttttcccatt cctccagctt ctgatccgac tggttgtttg
    40621 gttcaatcac agcgctgtct tttttcccct ctctgttttc cccgactgtg gcaatgcggg
    40681 aggttgtaat cttatccctg gccgttacca ttccattctt atctttagcc gtctcgaccg
    40741 gccacacgag aattctatct gccgtgtgct ttccctcctc gttaagcttc ggttccacta
    40801 cataagccat tcctgtctgt ggatctacca gggaatctct gtttccataa gaatctaaat
    40861 ggtaaaccag ggttccctct cccatcttcc actctcccgt ttttgtaata cggcagggag
    40921 tggcgaaggt tccttttaat accttatcca caggatgata gcttaatttc gtcagatctc
    40981 ctccagaaaa ctcaagataa ggctttcctc ccttaaaagc aaacagcgtt ccttcttcat
    41041 ctttttgcat ctgatccact gaaaccttct ggtgagattt atcccagcca agcagtttcg
    41101 ttttcccgtc tatccgttct ttccatgtaa gcgaaagatt gtctaaatca tagtataaaa
    41161 tctccgtatc tggccgttct accgtcccct ccttccatat atggcccttt tccttcacta
    41221 actctgtctt tttccctgca tacccccttt tgacaatcat ttccttcaca ttgccgttta
    41281 cgcttcttcg aatctccagg ccttcatagg aaaaatcctc tgtatctcca gaaggcttca
    41341 gctcaatcgc gtcaaacagc gtcattctgg cccctgccgt atacggattc ttgtcatcat
    41401 ttgtttctct gtcttttgtc acatagccgt accctgcaaa gtgggttccg tcatagacca
    41461 gctccacctg ttctcctacc tttttaaggg cagaaaggcg ttccagagtt cctttcggat
    41521 aagcatatcc cagatatacg ccattatcgt cgtaggcata ctgcagcgct ggatttcctc
    41581 caatttctgt cagacttccg tcaatcctct ccccaatttc aaacgtaacc gttcccttct
    41641 ttttaagctt ctctaccttc agtttaatcg gaatattttc cacataaatc tgggcagttc
    41701 cagctttttc agacgttttc ttatcctcgg actctccgtt ttttccgtct tcgtaaactg
    41761 ccgcaagaac cctctgctct ctctttccct cctcatagta agatacctga tcagaataga
    41821 tttcaacggc aatgggagct gtcctgacat agcctctggg cggaatctct gccagcacat
    41881 aaacgcctgc tccaagaggc tctggagtcg tcagataacc gcctgcctgc aggcgatatt
    41941 cctttggttc ccggtttgtg tcctccttct tcatctctat ctcatgcaga gtggaaaacg
    42001 ctgcaaactg tcccgtctca tttccggctg tatctttcat gacaatttta tcttcctctc
    42061 tgcacacagg agtctgagct ttcacgattc cggaatactg cattcctgga gccgttcttt
    42121 tttcctctgc cttttgtctc tccttctccc ctctctcttt ttctctcttt ataggagtaa
    42181 tgtcagacgc ccccatcgcc tccaggaatt ctctgctccc tgtaataagg gtatcttttt
    42241 cataaaactg cgcttttcct gtttccttgt ctctggcagc cttataaatc ataaaaacag
    42301 ccccgtcatg aagcagattc tcgtgagttt cgctgtccag tttttcaatt ctgagccttg
    42361 acgaataaaa agtatttctg aatttctgat ccgcataccc tcggaatgct tccggctcat
    42421 acgctccttt tatcggatcc agcacagaat atggaaccag catagggcca tactgccctt
    42481 cacaggcagt ctgtattccc tgcatagctt tgacatcctt ataaactgct tccgtttttt
    42541 tctcaaaccg cacctttttt gcagtacctg cctgctctga cacagaacca tagatgcagt
    42601 atttcccttc tcccgtcaga ctttgtcctg gaatctgacg cgctggataa taataatcct
    42661 tccacggttt aaaaggcttc tgtccaatcg aaaagccctg ataatcatag cttcctccat
    42721 cataagaaat cgttcctttc agcttatctg gctccagccc atatttatag atttcaaaat
    42781 ctcccgtatg gttatgagcg cggattacat attctctctg ttcggacgca tgctgatccc
    42841 attcctctcc aaagcggatc aaaaaacgct cctcttccgc ctgttcgttc agtgaaagag
    42901 cagtctgata cacgtacttc cggctgaggg cagtctcctg gtctttcgct tttttcgctt
    42961 cataaacgct tggtatctga atttccttcg gacagtcgat tttatactgt cggttttcca
    43021 tcctcttttt cggctgctgc tccgccacca cataagcccc gtagggcaga tactctgaca
    43081 gtccataata accggactga tccccattct tctgggaaac ttccagcgtc gtcttatctc
    43141 cgtctgagcc tccatcctct tctgagtccc agcaaatggc atagatctga tccagatcat
    43201 actggaaaaa tggtttcaga taatgatacg ctttctcaag agcagcgttc agggcttcgt
    43261 catagacggt ttctgacgac aggttttgct ccctgtcatt tttgaacgca tcctccttct
    43321 ccccattatc ctttaacagc tttgctgcct catcgtctaa ataccaggtt accgcaaact
    43381 gtcttacccc atcggaggcc tttgcattat tcacagcata ctcagttctc ttcgcctgat
    43441 tgcccaaagg tctccaggat gtgtaggtct gcgctttcgt atcccattta tctgtattta
    43501 ccgtctccag cgcatcaaaa aatttatcgt aattatactc ctgtattgtg actggcccgt
    43561 tttctccctg taccagcctg tcctccgtct ccagaagcct cgtatagccc ttattggcct
    43621 gcttccttat ctgatgagtt ttttctgtat tttcgttgtt tccccgatag ctgtacagag
    43681 ccgcattgac aatcactccg gctcctcccg gagcaatgga ggtcgaaaac ggagtttgtt
    43741 tcgcggcatt ttcatctgcc gtttccggat cctgataatc agcaagaatg ttatttccat
    43801 tgatgcttgt cagggtagat ttcacattat gcagaacctt tgtataaagt tttggcacgt
    43861 tcagcttccc gtttcccgca gactgcggac aaagggaatg cagcatgttc tcatacggca
    43921 gttcatttcc gtttcgatcc atccagacaa tggttccctc ttcatcacga tacagcctct
    43981 ccaggttgct tttcagatat gccttaaact gaaaacctgg ttctgcttct gtctcatcag
    44041 cgccatatgt attgttgtca taggttccgt ctggatttgt ataaatatcc ttaaagatct
    44101 taactctctg acggatggga cgttcaaaca cctgggatgg ataggttctg gttttctgat
    44161 cttcatacag cttttcctgt ccaggataag acaaatctgc ctgaaccaca taggaatttt
    44221 caccctgcat ttccatagtg tctgcgtcca ggcacgccct ggctctggct ttcttgacat
    44281 ggataaagta ggaagcactt cccatgggtt ttccggctgt aaatcccggc attagatcct
    44341 ccgtgagaat ctttacgtcg tcctctgaca aaattatatt tttttcaaga agaaccgctt
    44401 taaattctat ggtctgatcc tgcccctgat tggtatgcgg cacgccaaag gagtctgtgt
    44461 aggaggcgtc tgctgtgaat agatacgttc catcctgcct ccgctctgcc ggaatctcct
    44521 tccacacggt ctcctccacc tctataatct ctgtttttaa aatttcctga tactcaaatg
    44581 cctgaatcag atttccattc ttatccctca ccagctctcc tggcttatag tattcgtttt
    44641 tcaatactgt tttaggaatc agggttccat ccgctgctgc ttctgcatct gaaatcaggc
    44701 gcgcagaggc aaatacagcg gattccgtct gtgtttccct gtattcctca taagttccaa
    44761 atgttccgta atctgaattg ttggaataat ctgcataaat cagacgagga gaacgggttt
    44821 tatcttccgg aagccaggga acagacttaa aaatcaggct gtccttctcc ggatctgaac
    44881 ccagaaccat aaaatattct ggatttccag aaattcctgt atatacagta aatactaatt
    44941 gtccattctt ctcctctgca gcgtctattc cgccatagct gtaataaggg tggctgttat
    45001 aataatccaa tacggctgac acagcgtctc ccactgtgag gaaagaaccg tcttcttttt
    45061 ccgtatccat aaccagagtt gttacaggag cgccatatac agtatcggca gctggttctc
    45121 ctggctttac gcctgaaatt cctcctggat ctggttctcc ttttcggaca cctctgtcaa
    45181 aaatatctct gtaaatgtca gaataacttg tctttcctcc ttctttgatt
//
LOCUS       DBMDUW010000017        44599 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_755_length_44599_cov_3.932873, whole genome shotgun sequence.
ACCESSION   DBMDUW010000017 DBMDUW010000000
VERSION     DBMDUW010000017.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 44599)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 44599)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44599
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_755_length_44599_cov_3.932873"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            373..759
                     /locus_tag="ACZPCR_05090"
     CDS             373..759
                     /locus_tag="ACZPCR_05090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005950968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0046914 - transition metal ion binding
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HIR1230283.1"
                     /translation="MKIQQSAEDYLETILVLSRKKSQIRSIDIVNELGYSKPSVSVAM
                     KNLRENGYISMDRDGYITLEEPGLRIAETIYERHTFLTGFLVCLGVSPETAAEDACRM
                     EHVISPESFQAMKRFAEKNLKEQDVR"
     gene            complement(843..1124)
                     /locus_tag="ACZPCR_05095"
     CDS             complement(843..1124)
                     /locus_tag="ACZPCR_05095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004845731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HIR1230284.1"
                     /translation="MSVVIVGGHDRMVSQYKQICRNFKCKAKVFTQMSAEFGKQVGSP
                     DLLVLFTNTVSHKMVRAAVEGARGTRTEVVRCHTSSQSALADILEKRCM"
     gene            complement(1145..1576)
                     /locus_tag="ACZPCR_05100"
     CDS             complement(1145..1576)
                     /locus_tag="ACZPCR_05100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005351104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HIR1230285.1"
                     /translation="MNQILIVYWSGTGNTAAMAEMVASGIREAGKEPVLIPAEEAAAE
                     QLSSFQAAAFGCPSMGDETLEESVMEPFVEAAEKNVSGKTIGLFGSYGWGDGQWMRDW
                     SDRMKQAGAYVLGGEDAICCGAPDASAEEALKELGRQLAES"
     gene            complement(1640..2251)
                     /locus_tag="ACZPCR_05105"
     CDS             complement(1640..2251)
                     /locus_tag="ACZPCR_05105"
                     /inference="COORDINATES: protein motif:HMM:NF024084.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HIR1230286.1"
                     /translation="MDQRLYSREQNAIQKQAAFHCAQVLAGVKASNILITTEGTEEDV
                     AFVLRGTGVDCKCLWAGEGRTVYLLYRREQTEKILKSRETRSFFQGFGYSSMELSKAL
                     SGLAARYGLYAEGKGEFPHEIGLILEYPIWDVKGFIEHKGRDFLFSGYWKVYREPEEA
                     RKRFAVYTAVRERVVKEAERGKSLGQICASLLGQPVYSLTAAA"
     gene            complement(2462..4993)
                     /locus_tag="ACZPCR_05110"
     CDS             complement(2462..4993)
                     /locus_tag="ACZPCR_05110"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013100.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008955 - peptidoglycan
                     glycosyltransferase activity [Evidence IEA];
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HIR1230287.1"
                     /translation="MDRERNERGHTRGRQGQKTPGPADAQKRQDRKEAKRLQERRAEE
                     AVQQELGEQIQSILEEETGEQEGARQQKAAGPDPLSWEPAARTEEEAGRRRRPARQKK
                     GWRRLWKRFFLMFLLILFVAAAGCGFLGWKFYTICKEEVDGLVANSTEADFLPGQASY
                     FYDVNGNVLAKISGDEDSQYLPYEEIPQDAVNAFIAIEDRTFWENCGVDFKGILRVGI
                     NFILTKGEEVHGASTITQQLARNRYLTRDVSIKRKVKEILIAMDLTEKYSKEQIMEFY
                     VNDINYANTYYGLQAAAKGYFGKDADELSLSQIAYLCAIPNSPSYYNPYRHPDHALTR
                     RDKILGDMLTMGYITQEEHDAAVAEEITVTGNSYEMRNYETTYAIDCAVRWLMEREGF
                     SFEYGFSSYDDYKSYQAAYEESYAAAKDELYTGGYRIYTSLDPAKQEILQSAVDQVLS
                     FDAETADNGIYALQGAAVAVNNDTGLVEAIVGGRSQETSTYTLNRAFQSFRQPGSSIK
                     PLIVYAPALEEGYASFSSVKDINVDAAKEPKADVASLPGNWITLRQAVEKSRNGAAWW
                     LFNEVTPEEGLSYLTQMQFDKIVPDDYNMAASLGGFTYGVTAEEMAGAFSALENGGVY
                     REPDCIVRMENLAGEDIYTGREPKEVYSQQTAAVMVDVMKGVISRGTARGMGWKSGIE
                     AAGKTGTTNNSKDGWFCGMTPYYTVTVWVGYDTPRTLSSLYGSSYPASIWKQAMEGLT
                     AGLPEAAFAAPEAEKEDIKKEGRGEYLEGYDDSHVLSPNYTVGDYRRDHALADEAQKY
                     IDQMAGASPEEQERLRKKAESAINRIYGRTLKGQMEEVLAGAGKS"
     gene            complement(5166..7802)
                     /locus_tag="ACZPCR_05115"
     CDS             complement(5166..7802)
                     /locus_tag="ACZPCR_05115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004221552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HIR1230288.1"
                     /translation="MYEGKTIDETLKKLSADGERGLREEDVKERQKHYGSNELEEKKQ
                     KTLLKRFAGQLCDSLIFVLFAAAGISVLLGEYSDAVIIMIVVAVNGIVGVVQEGKAQK
                     ALDSLKQMTRLKASVVRDGREIEIDAKELVPGDLALLTAGCQVPADMRLIQSAGLKIE
                     ESALTGESVPVSKSADYLASESGTGNGSGKGKNMAYMTSYVTSGRGKGIVTATGMGTE
                     IGRIAAMIHAAPEEETPLQKRLGELGKVLSLTAVALCAALFLMAVIQKRDVMEMLITA
                     ISLAVAAVPEGLPAVVTIVLALSVTRMVKAGTIVRKLPSVETLGAVSVVCTDKTGTLT
                     KNVMTVTQWYEDGTIRTLENAAAEKPSKRLAECFALCSDARLEQEKGDPTELALLQFA
                     SLADVEKEEMEREMPRKGELPFDSDRKMMTTFHRQGKTGISCTKGAPDRVLRQCTHIW
                     KNHRSVPMTEAERREAEQAAARMSSQALRVLAAAAKEDAAGPEEKGLTFLGLAGMMDP
                     PRDEAKQAVGQFRKASVDTVMITGDHVDTALAIAKELGIAEDRTQCMTGEELERTEDD
                     ELKKKIKHLKVFARVSPGHKVRIVNAFKAAGHITAMTGDGVNDAPSLKNADIGIAMGK
                     TGTDVAKQAADMILTDDNFATIERAMEEGRGVYENIKKSVIFLLSSNFGEIATMFAAI
                     AAGVASPLKPSHILWINLITDSLPALALGVDENDGRRLMEKPPRQSGESLFAGGGWFV
                     TLGYGFLIAAVSLTAFFRLPMELAGSMELSSVRECLQNPEVLLKSQTYAFTVLSLSQL
                     FHAVGMRDVSSSVFGSRLCSNRLMLLAFGLGMLLQAAVTEIPALTQAFGTCVLSLSEW
                     GFLLPLAAAPVIVHEIAVLLRR"
     gene            complement(7982..9046)
                     /locus_tag="ACZPCR_05120"
     CDS             complement(7982..9046)
                     /locus_tag="ACZPCR_05120"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230289.1"
                     /translation="MKKTTFAAGLCASALSLALLPSMHSMAERNQMITWEKTGKNSVR
                     LKLKLQDQEPADSFTAFSLKLIFESDEPMSEDPAFKFSQNIKSKLDPAVYETRYDEDA
                     QEMTVYVADRDPVLEKGEELDLGTITVDSEENVRISVDRDDFQGVNSFHEKLEVTNFG
                     EYEDYEMILETPEPEEPETEDPETPEPEAPDTPDEDTEDDDSDRNSGRGNSRSEWTEK
                     PNGSWKQDGRGWWFAKLDGSYPADGWFECSWNGKKGWYHFNAEGYMETGWFTDKDGHT
                     YFFHDQNDAKIGAMYTGWRWIGDNCYYFTKDSAEGQPAGSMVKNGKTPDGYTVNAQGQ
                     WTVNGIVQINPEKPSGPGLS"
     gene            complement(9083..14425)
                     /locus_tag="ACZPCR_05125"
     CDS             complement(9083..14425)
                     /locus_tag="ACZPCR_05125"
                     /inference="COORDINATES: protein motif:HMM:NF024794.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin type III domain-containing protein"
                     /protein_id="HIR1230290.1"
                     /translation="MKRQLAFVLAAWIGLQQPLGTLEAYAAQPLAAGVTGGSQSEWLP
                     VSSPSNGQEEETETLPEATPDAPLENPYRGNVIVEIRTVLPVEGEIPFEVHLTEKPSK
                     LAKFLRQEAEVNEYGQFTVQPGEMSEIGKGVFQSNYVPDGTYVLTVNAEGYEPYKQEI
                     KIKGDTCKVMLFNDYYDEEQYTSSAHPGLIRMGDVNGDDIIDDEDLEELLDAIHAEEP
                     GVNAMDFNQDGELNLSDLQYFASFYDYDSSSRKHISTVERSVTRKEGEVKFDDTASPS
                     DAVEIDGKPEALFDHDSEESSVTVARKDGEKISEENPVELTLDFTHSETELKAEGFVI
                     QSPSGSENAITSGEIEVTVDDDGKEKKETLTIVKAGEARKARFGRSGGTAEIQPDGSI
                     VVNLKSQKPVKKVTIRVTGTVSQGSLAEISQVEFMEDMKDRIPPPVQNIPKNLQAEIG
                     SAEFTLIWDKENNVTGYEISISHDGETETMASEENSVTINSFGGKKLLNYETYRVRVR
                     SVNGTWKSNYSSELSVTPEPSGPPPAPEYIKIDGFYRCLNVSWKKMKDTQSYTLFYRQ
                     KGTEEFTAVENIDRSQTSLTLEHLADNTEYEVYMVGHNPLGDSPDSTMYSGRTAPAAT
                     AKMPAYGLLNDGPDKGKDVTNHIKKVENIEGANYNRADEEIAIPTVIVDGDPTSYWLL
                     EDWDSGVHYGSRGPIITLDQPYEMDTIRFTAGPAQKSDLSAIKVLAWETEDGSGSGKE
                     IPGRFSRLASMDNNGSVYYEFIASEPFTAKKVQINLSASGNVRYISIGEIRFYEYNSL
                     LNDIDALFTDALHVALKAEVTMDDVKALKERANELDPASGETHPKKELALKDLSVAES
                     ILLTGVSQEAVQIDTSVSKSYDSHITFLGGLNAWQPLGTAALAGEKVTIYVGAPGKTQ
                     GDSTPLKLVATQYHSESSPFYKYASDLKVGVNEIIIPKISSIDCEQGGALYVEYTGRN
                     INDSYAVRVSGGSPYPVLDLTKAENEDERAQLIETYFTEMEERVKELEALHNADPDSE
                     TSHRHISGKEYDEKNCILGATDIVLDQMMYSVAIKPLYDELTKRSDKKEDAVQQLTDS
                     LNAMDAMIDLYYQHKGLSDNPVMDGVTYGKDRTPTSRLNIRYQRMFAGAFMYAGGLHI
                     GIEWGSVPALGGSKPIETDENGKALENQDGQYFGWGISHEIGHIINEGAYAYAETTNN
                     YYPQLAKSRDSNDTTRFSYEDVYKKVTSGTKGGGSERLAMYWQLHMAYDNGGYNFKTY
                     DNYKDQRENLIFARIDSYARDTSRAPAPGGIKLTLDNADKDNKMIRLACAAAEKDLRD
                     FFIRWGLTPDKTTDEYAGQFDEETRAIYYENDDSRVYRLEGGESIAESVTVKAEAEKD
                     SQASNQVHLTMSLSDEGKRDQLLGYEITRIERRYGKEERRVVGFTTSDTFTDHVMTTN
                     NRVVSYEMRGIDQCMNPTETYRISDEFKLLHEGMLDKTDWEITVNTTSPSDEKPDNED
                     ETDTPCSGTISAAGMMIDNQLDQAYVGTTTEKEAEAVISLGKTESIAGFKYTYDGENP
                     VKNYRLSISQDGEKWTEIKSGTFEFQEGSSSALIYFDLKDDPRYHVYETAYLKITAAG
                     SKSFAAAELDILGPTGDNVELAEAGIGILKEDFYLTDAGSGETGEETADKIPAGSVIF
                     TGKYKGNPAYNTFILYDEDGNVVGGRDADGAVTAHQLIFAPDPVNGQLGEITDGIWVY
                     YIEPDELDGVTLPGKVRAEMYRVDNAETNEGDRLVSDTLFVELPKNLPDIEIKP"
     gene            complement(14646..15071)
                     /locus_tag="ACZPCR_05130"
     CDS             complement(14646..15071)
                     /locus_tag="ACZPCR_05130"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230291.1"
                     /translation="MAVTKDKKYAETLICAGDSTDCSVEDLENYLEEYDLMYFDEGSG
                     ARRTGTVELVSKGETCTFEFHGSGKAVHGPHQGKLYRAGALQRAEDVGKYEIRTVDDK
                     DYLVNRSGEIQSPGRYRDGGTVWVVERKDGAYEISAEDA"
     gene            complement(15062..15490)
                     /locus_tag="ACZPCR_05135"
     CDS             complement(15062..15490)
                     /locus_tag="ACZPCR_05135"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230292.1"
                     /translation="MPVYVLTDFVYDVTAAGWRCLPVQRENGGREQRWFYFYPNGKKA
                     ADTSITESDENGRYRYTFDENGMMRSSKKLGSSPNTLTEQWIERVPKASQDSYASENH
                     IKRWYYGLSDGTVVQNRMRNIGGRSICSTRQELCGLAWWL"
     gene            complement(15472..16317)
                     /locus_tag="ACZPCR_05140"
     CDS             complement(15472..16317)
                     /locus_tag="ACZPCR_05140"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230293.1"
                     /translation="MSKKIYTVSMILVLLIAGGAAAFGISRHVQNAEAFWGDGYVLSY
                     QNGKNGSVVPEPLYFKAGTRYKENYSGNISFKDMYGKKQEVPADSFIHYADDSISTFH
                     KGVIVECNELKKGLLNYYSLGAESVMNRQGDKYLLDNQGTPLEFQDYIWKMQEEKYLV
                     SSPEISLTFPDGTEESLKGYAELAYIDRGIVRISGGETAFQVLASGSRMRLADGTELD
                     LENRSIVQNEEVSLYFSEIRARPERQALRARLEKPEKQEHPDLLATEAAAEISPIRSL
                     CRFTC"
     gene            complement(16595..18286)
                     /locus_tag="ACZPCR_05145"
     CDS             complement(16595..18286)
                     /locus_tag="ACZPCR_05145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HIR1230294.1"
                     /translation="MKKKFALMLAAAMLSTTVLTGCGGGGSEETKPAASEDGQAAQTG
                     EGGNNLVVEIGPDPETIDPALNSAIDGANMIIHLFEPLLNFDKDNNIIGGMAETWEVS
                     EDGLTYTFHLRDGLKWSDGTPLTANDFVYTFKRVADPLTAAPYGYDLLCMVKGYDEAA
                     AGDLDALAVSAPDDQTFVVELSYPCVYFDKICAFATLSPVNQATIEANGESWAIDPST
                     YICNGSMKIKEWVPGSHILMEKNENYWNADAVTADTIKFVLMEDMNAAYSAYNAGEVM
                     FIKDVPTEEVPNLRENPEFHVDPLLGTYYISLNLNRDYFKDVKVRQALSLALDRAYIA
                     DTIMQGTYSPATNFVGPGVSDVEPGSSFAEVTIAENGEFFHTDDFEGDLAKAKELLAD
                     AGYPNGEGFPAIEYMTNDAGYHKPLAEYLQSAWGELGITMDIKVVEWATFTPTRRNGD
                     FDIARNGWVYDYDDPSNMLNLFETENGNNDGKYSNPEYDEMIANARMTADKEEHYKLL
                     HEAEQLLLNDMAMIPIAYQNDFWLQKPELQGTWHSPYGYWYFMYGTVGEAAETAE"
     gene            complement(18556..20241)
                     /locus_tag="ACZPCR_05150"
     CDS             complement(18556..20241)
                     /locus_tag="ACZPCR_05150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HIR1230295.1"
                     /translation="MKKKLALVLAAAMLSSAVLSGCGGNDSKPDGGEGQEAQAGEEGN
                     HLVVEVGPDPETIDPALNSASDGNIMIIHLFEPLLNMDKDNNIIGGMAETWDVSEDGL
                     TYTFHLHEGLKWSDGTPLTANDFVYTFKSVSDPMTAAPYGYDLLCMIKGYDEAAAGNL
                     DALAVSAPDDQTFVVELAHPCVYFDKICAYTTLSPVQQATVEANGEAWAIDPATYICN
                     GAMKIKEWVPGSHILMEKNENYWNADAVTADTIKFVLMEDANAAYSAYNAGEVMFIKD
                     VPTEEIPKLRENPEFRVEPLLGTYYISLNLNRGYFQDVRVRQALSLALDRQYIADTIM
                     QGTYTPAKNFVGPGVSDVEPGSSFSDVTIETYGEFFHTDDFEGDLAKAKELLADAGYP
                     NGEGFPMIEYMTNDAGYHKPLAEYLKSAWGDLGINMDIKIVEWATFTPTRRNGDYDIA
                     RNGWIYDYDDPSNLLNLFETENGNNDGKYSNPEYDTKTETARKTADREEHYRLLHEAE
                     QMLLEDMAMIPIAWQNEFWLQKPELQGTYHTPYGYWYFMYGSVGEAESPEETK"
     gene            complement(20375..22093)
                     /locus_tag="ACZPCR_05155"
     CDS             complement(20375..22093)
                     /locus_tag="ACZPCR_05155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HIR1230296.1"
                     /translation="MKKKFALLLAAAMVSTTVLSGCGGSKDSSAGAGDAGVVAEEGNH
                     LVVQLGPDPETMDPALNSAIDASNMIIHLFEPLLTMDRDNNVIGGMAETWEVSEDGLT
                     YTFHLREGLKWSDGSDFTAEDFVYTFKRMADPMTAAPYGHDLLCMVKGYDEAENGNVD
                     ALAVSAPDAQTFVVELSYPCVYFDKICAFAALSPVNQATVEANGESWAIDPATYVCNG
                     PMKIKEWVPGSHILMEKNENYWNAEAVTADTIKFVLMEDMNAAYSAYKTGEVMFSRDV
                     PTEEIPNLREDPEFHVAPILGTYYVSLNLEREYFQDPKVRQALSLALDRQYIADTIMQ
                     GTYTPATNFIGPGVSDAEAGVSFQETTIAEYGEFFHVDDFESDLAKAKELLADAGYPN
                     GEGFPMIEYMTNDAGYNKALAEYLQSAWGELGINTDIKIIEWASFTPTRRNGDYDIAR
                     NGWVYDYDDPSNMLNLFESTNGNNDGRYNNPEYDALIASARETVDKAEHYSLLHEAEQ
                     LLLNDMGMIPIAYNNDFWLQKPELQGTWHSPYGYWYFMYASYGDAGQAEEAAPAEAET
                     SAEAAE"
     gene            complement(22181..23242)
                     /locus_tag="ACZPCR_05160"
     CDS             complement(22181..23242)
                     /locus_tag="ACZPCR_05160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1230297.1"
                     /translation="MENKKLLEIEHLKQHFPVASGKLFEKKVVKAVDDVSFFINKGET
                     LGLVGESGCGKTTTGRTLLRLYEPTSGRIAYDGTTIFDSGDVPLTDENGQPVLNEKGE
                     VQFGHKTKVNMLPYRRKMQIVFQDPYASLDPRMTVADIVGEAIDIHKLASNKKERQER
                     IIRMLERVGLNSEHANRYPHEFSGGQRQRVGIARALAVDPEFIVCDEPVSALDVSIQA
                     QVVNMFEELQQEMGLTYLFIAHDLSIVKHISNRIGVMYLGKLVELADSYELTFHSVHP
                     YTKSLISAIPIADPKTSRESKRIVLSGDVPSPVNPPSGCTFRTRCPYATELCAEKAPE
                     WREVSKGHYAACHHLDKIN"
     gene            complement(23242..24246)
                     /locus_tag="ACZPCR_05165"
     CDS             complement(23242..24246)
                     /locus_tag="ACZPCR_05165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012200020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1230298.1"
                     /translation="MSEYLVNIKNERLSFFTPAGEVKALNDVSLHLKEGEVLGIVGES
                     GSGKSVTAYSLMGLTAYPGRLIGGSIEFNGHQIDQMNEAQMRKIRGEEISLIFQDPMT
                     SLNPVYTIGNQICEMILLHTKKTKQEARERAKELLTLVGINEPEKRLKQYPHELSGGM
                     RQRVMIAIALACEPKLLIADEPTTALDVTIQAQILELMMELKQKLGMAIIMITHDLGV
                     VASMCDKIAVMYAGKVIEYGTTDDIFYRPSHEYTKGLLRSIPRLDEKEKTRLVPIEGS
                     PVDMLNPPAGCPFAPRCESCMKICLKQMPEYTDLSDIHYSACWLLQKEEFLKAQGGDK
                     "
     gene            complement(24260..25300)
                     /locus_tag="ACZPCR_05170"
     CDS             complement(24260..25300)
                     /locus_tag="ACZPCR_05170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1230299.1"
                     /translation="MEKNKLSFQLNADDFLPAGEDEKKSLVVMRESVGFWKDGMRRFK
                     KNKIAMVSLIVVILIFILSFIVPQFYPYKYEQQIKGSNSLAPFEYSQAEQEAIANGEK
                     VFPHILGTDQLGRDYAIRVMMGSRVSLTVGLVASAIILLIGSLYGSIAGFFGGWVDMV
                     MMRIVDIIYTVPDVLIVILLAAVLNYPLKELAMKPGFEWIGLIGVNLISIFVVFALLY
                     WVGMARIVRSQIMILKEQEYVTAARALGASSGSIIKKHLLTNCIGTLIVTTTLQIPSS
                     IFTESFLSFLGLGVNAPMPSLGSLASAALNGLQSYPYRLFAPALMISIIILSFNLLGD
                     GLRDAFDPKLKN"
     gene            complement(25314..26231)
                     /locus_tag="ACZPCR_05175"
     CDS             complement(25314..26231)
                     /locus_tag="ACZPCR_05175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013272520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1230300.1"
                     /translation="MAKYILKRIGLAVVTAWLVATLTFFLMNLVPGGPFMAEKALTPQ
                     AQEAMMEKYGLDKPLPEQYVIYMKDLLHGDLGPSVKQRGRTVNTIIETKFPVSAKIGG
                     VAILLAVCIGVPLGSVAAFNRGKMVDNIIILFTTCGIAIPSFVICTLLMQILSNWLGL
                     LPTYGLTSWKHYIMPVISLALYPSSYIARLMRSSMLDVLGQDYMRTARAKGVSWMVSV
                     FKHALRNAILPVVTYLGPLLAYTVTGSFIVEKIFTIPGLGSEFIGAITGRDYPLIMGT
                     TIFLAVLIIVMNVIVDIAYTLIDPRIKLK"
     gene            complement(26395..27327)
                     /gene="tsf"
                     /locus_tag="ACZPCR_05180"
     CDS             complement(26395..27327)
                     /gene="tsf"
                     /locus_tag="ACZPCR_05180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019162109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HIR1230301.1"
                     /translation="MAVTAAMVKELREMTGAGMMDCKKALAATDGDMDKAVEFLREKG
                     LAGAAKKAGRIAAEGIVMTKMAADEKTAVVVEVNAETDFVAKNEKFQNYVADVAEQAL
                     ASDAADMDAFMAEKWAKDETLTVAEALSSQISIIGENMKIRRYEKMTAANGFVASYIH
                     AGGKIGVLVDVETDVVNDEIREMAKNVAMQAAALKPLYTNRDEVDADYIEKEKEILTV
                     AAKNEKPDANDKIISGMVMGRINKELKEICLLDQVYVKAEDGKQSVSQYVAQVAKANN
                     AKVAIKKFVRFETGEGLEKKEENFADEVAKQMGM"
     gene            complement(27450..28184)
                     /gene="rpsB"
                     /locus_tag="ACZPCR_05185"
     CDS             complement(27450..28184)
                     /gene="rpsB"
                     /locus_tag="ACZPCR_05185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009299114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HIR1230302.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAPYIYTERNGIHIIDLQ
                     KSVGKVDEAYKAVSDIAAEGGTILFVGTKKQAQEAIKVEAERCGMFYVNERWLGGMLT
                     NFKTIQSRINRLKEIETMAEDGTFDVLPKKEVIALKKEWEKLEKNLGGIKEMKRIPDA
                     IFVVDPKKERICVQEAHTLGIPLIGIVDTNCDPEELDYVIPGNDDAIRAVKLIVSRMA
                     DAVIEANQGEAEAPVEGEDAEETAEA"
     gene            complement(28330..29919)
                     /locus_tag="ACZPCR_05190"
     CDS             complement(28330..29919)
                     /locus_tag="ACZPCR_05190"
                     /EC_number="1.8.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009289827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0050311 - sulfite reductase (ferredoxin)
                     activity [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HIR1230303.1"
                     /translation="MGNEAWKQDLAEFKAVTEKFYNKEVSAKDYKGFSGGFGSYAQRG
                     AEASMLRLRLSGGRMTKEQLKFIGDSIEKHQINQVHFTTCQTVQLHNLNGTSVCEIME
                     EALDVGINTRGGGGDFPRNVMVSPLSGVEQGEWFDVLPYALKAAEYLMGFIKTVKLPR
                     KLKVCFSNSPANRPHATFRDLGFAAREDGLFDVYSAGGLGANPKMGVLVAEAVEPEDI
                     LYYIKAMVNTFTAYGDYENRAKARTRYMQDKLGKEEYVKAYQEKLKEVMDQEKDGLKL
                     KKEELFALHLEEKEKLASEILGQLTEEEKAALHCRRVTAQKQEGLFAVEFHPIAGSPD
                     PSLFKMLYETVKDMEQVEMRLDPEEAMYVINLTAREALQVLDVLKDSAENLFETSVAC
                     IGSFICQVGVRDSQNLMKSIVEEVRKHSFKDGTLPKIHISGCPSSCGTHQAGTLGFRG
                     GVKVIDKVPKPAFNLHVNGNELQGEERFGEDWGAMLEENIPAFMAEVGETVEKAGQTF
                     AEWFPEHRETLKEIAEKYMAQ"
     gene            30130..31056
                     /locus_tag="ACZPCR_05195"
     CDS             30130..31056
                     /locus_tag="ACZPCR_05195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HIR1230304.1"
                     /translation="MLDNRIYTFLAVCQEMNFTRAAKKLHITQPAVSQHIQYIERYYG
                     VHAFRFEGKKLSLTPEGELLRSALLTMKNNEESLKTSLSKSAGQISPLRLGATLTAGS
                     FLLAEPLARLFRRWPDLPLSVTVKNTADLLAQIDDGSLDFALLEGNFSKASYSYLVYL
                     REPFIPVCGPDLLFQMKCMQKEKGLPLSLEQLTGQRLLLRESGSGTRMILEQILEERG
                     LFVSDFKNKAEIENMQAIKDLVAAGCGITFLYKSAVQRELCDGTICEIPIENLWLEHE
                     ISVVWQKNRLFQNQVTQAVKEAFGPGFGEELA"
     gene            complement(31053..32057)
                     /locus_tag="ACZPCR_05200"
     CDS             complement(31053..32057)
                     /locus_tag="ACZPCR_05200"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005341001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1230305.1"
                     /translation="MYLEMKDLSKSFDGKEVVSGLNLSMNQGEILCLLGASGCGKTTT
                     LRMAGGFLEPDRGHIYLDGEDITKLPPERRPVSTVFQSYALFPHMTALQNVMYGLKFQ
                     GMKKKEAAERAWEYLEIVGLADRASSSVQELSGGQQQRVALARSMAVNPKVLLLDEPL
                     SNLDAKLRIRMRDELKELQKKTGITMIFVTHDQEEAMALADKIAIMEGGRLIQMGAPR
                     EVYQNPASLFVMEFLGTADRAAMPDGSLIYFRPEDIRILGKAEETKARKDKGTERQAQ
                     NPDGRHLLTGTIVKSDYMGFYTQYFVKTEGGELLVREFEREYQNGDLVALELCGGKTF
                     "
     gene            complement(32029..33792)
                     /locus_tag="ACZPCR_05205"
     CDS             complement(32029..33792)
                     /locus_tag="ACZPCR_05205"
                     /inference="COORDINATES: protein motif:HMM:NF012738.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1230306.1"
                     /translation="MSRLTTKNRQNRGKRVSGLDALFSCAKDRKAFLGLCGDRLLFCA
                     MAAAVLLFVLWPLLGIAAKSVNLGEGVSLAAYENLFRENGVLIRHSAFTGVLAAVFST
                     ILGIAVALFIVTMKGGMKGIFMGILLMTMVSPPFISSLVYIQLFGKRGWITYRLLGLM
                     LSPYNKWGIIIMQTVHFASLNALFAVGILEKLDLRLLEASRDLGASPAQTMRRVVLPM
                     LKPAAGICFILSFIRSVADFGTPAVIGGRYNTLASAIYMELIGYADLEKASAMNMLLL
                     LPAVAAFLLYRVLMRQADRMTAADGQKQGKGGLPLPLAGWFGAAVRLLSSLFFVMMTL
                     QYLCIFLTGFLKSKKGRYYFSLDHFNGLLTYNIESLARSVLYSLITAAAGTLFAMLFA
                     YYLERRKVRFRGFYDFIATMPYLLPGTCFGIGYILVFNREPLKMTGTAAIIIFNMIFK
                     QLPMVMKLTSASLAQLNSRVEDAARDLGAGRFFVTKDIVMPNLKRTFVTGFIYNFSSA
                     MTTAGAVMFLISARHKLAVYTLFDAINSGEYGVASLISSMIIVITIAVTGGVSALVLR
                     EKPKKRKKEEARHVSGNERFE"
     gene            complement(33785..34903)
                     /locus_tag="ACZPCR_05210"
     CDS             complement(33785..34903)
                     /locus_tag="ACZPCR_05210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIR1230307.1"
                     /translation="MKKKSLAGIMTAGLAALMLAGCSSQGGQETTAASAESGAAQESS
                     AAAEETEAEAEEKKADGTLKVVATSEDYVKLFDKFTEETGIKTELLSMSSGEVLSKIK
                     AEGGTPMADLWFGGGIDAFMGAKEDGLLEQVNFDEAANLAPEYKDADNYWFAKGLTVV
                     GFVVNNDIIEEKGLEIPKSWADLTNTAYQGEIIMSNPAISGTNYAVVNAILQAKGEEE
                     GWNYFEELNKNIEYYSKRGKDPLTKTMAGEFAIGIAPMDREVDKLQEEQNMTAVYPED
                     GIPYVPEGVAVFKNSEGAEEAKEFIEWFYSDDENLKMAADIDNKDTIKMVKPDIEGLE
                     LTFDVESLMDEDLSLFGSQREAILAKWDELAGDKSENE"
     gene            35239..35868
                     /locus_tag="ACZPCR_05215"
     CDS             35239..35868
                     /locus_tag="ACZPCR_05215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002576866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HIR1230308.1"
                     /translation="MFVDLHMHERTFSKDSFLTLKEIVEIAKEKGLDGVCITDHDDIG
                     IKEYAEQYSRETGFPIFVGYEFYSLQGDILAFGAPKVPSERISAQEFVDYVKSFGGVC
                     IAAHPFRNNNRGLEENLATVKGLDGIEALNGSTLPDACSKAFSYAKRLGIQCTGASDC
                     HVPSKVGVYATWLPETVSTLDDFISVFKKGQCRPAVYKNGGYVVVEQAQ"
     gene            complement(36033..37655)
                     /gene="groL"
                     /locus_tag="ACZPCR_05220"
     CDS             complement(36033..37655)
                     /gene="groL"
                     /locus_tag="ACZPCR_05220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009267873.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HIR1230309.1"
                     /translation="MAKEIKYGVEARKALESGVNQLADTVRVTLGPKGRNVVLDKSFG
                     APLITNDGVTIAKEIELKDAFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAMINEG
                     MKNLAAGANPIVLRKGMKKATEAAVEAIQNMSKTVKGKADIARVAAISSADDEVGQMV
                     ADAMEKVSKDGVITIEESKTMKTELDLVEGMQFDRGYVSAYMATDMDKMEANLDDPYI
                     LITDKKISNIQEILPLLEQVVQAGAKLLIIAEDIEGEALTTLIVNKLRGTFSVVGVKA
                     PGYGDRRKEMLKDIAILTGGQVISEELGLDLKETTMDMLGRAKSVKVQKENTIIVDGC
                     GNKDEISARIAQIKAQIEETTSEFDKEKLQERLAKLSGGVAVIRVGAATETEMKEAKL
                     RMEDALSAAKAAVEEGIIAGGGSAYIHATKEVEKVVEAMDGDEKTGGRIILKALEAPL
                     FHIAANAGLEGSVIINKVRESEVGMGFDAYNEKYVDMVEAGILDPAKVTRSALQNATS
                     VASTLLTTESVVANIKEETPAVPGGAGGMGMM"
     gene            complement(37725..38009)
                     /locus_tag="ACZPCR_05225"
     CDS             complement(37725..38009)
                     /locus_tag="ACZPCR_05225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008721713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HIR1230310.1"
                     /translation="MKLVPLFDRVVLKQLIAEETTKSGIVLPGQAKEKPQQAEVIAVG
                     PGGVVDGKEVSMQVKVGDKVIYSKYSGTEVEVEDEKYVVVKQNDILAVIE"
     gene            38611..39057
                     /locus_tag="ACZPCR_05230"
     CDS             38611..39057
                     /locus_tag="ACZPCR_05230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230311.1"
                     /translation="MAKKQFGKLAVLAALAGTAVGITYFLRYKSFHEELEEDFHDFEE
                     DLDEFDSKEEEASAKRNYVSLTPEKADSAQKETVPASAKEHPAAEQSPEAEKKADETQ
                     NDFLDSDMEFLDDEPMDGESMFDEEDIPDTASSSATTIVEDEEPEQ"
     gene            39076..39837
                     /locus_tag="ACZPCR_05235"
     CDS             39076..39837
                     /locus_tag="ACZPCR_05235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HIR1230312.1"
                     /translation="MIQSLMRSLDLLEVLKGADHKISIAELSEQLELPPSTIHRILHT
                     FCEKKYVIRDEYTHTYCLGPALISLGRAAASNVRIQDAALPILKNLSYVTREDSYLVI
                     QVGDKGLVLDKVDGPNHLKVVEEFGYELDLHCGAIRKVILAYQSPEYLDYYTRQVLDR
                     PEAFPQTSRSGLLAELREIRETGLSVSHGEYVHDAIGIGAPVFGINGSVTASVGIIAP
                     YSRIADKVHLEHMKEQVRHSAAELSYYMGHTFKQV"
     gene            complement(40053..41201)
                     /gene="hgdB"
                     /locus_tag="ACZPCR_05240"
     CDS             complement(40053..41201)
                     /gene="hgdB"
                     /locus_tag="ACZPCR_05240"
                     /EC_number="4.2.1.167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyglutaryl-CoA dehydratase subunit
                     beta"
                     /protein_id="HIR1230313.1"
                     /translation="MSINTLLDEFKVKAATPKQQLAEYKAQGKKVVGVLPYYAPEELV
                     YAAGIVPMGIWGSNTKTISRAKEYCATFYCTIAQLALEMLLDGTMDGLDGIITPTICD
                     TLRPMSQNFRVAMGDKMSVIFLAHPQNRFEEFGLQFTVDQYNHVKKELEKIAGREITN
                     DDIQNAIKVYNESRAARRKFVKLASDHCDVITPTKRSAVLKAFYFMLKDEYIAKLNEL
                     NAELEKLPVCDWQGTKVVTSGIICDNPALLAAFEENNIAIAADDVAHESRSFRTDVPE
                     NADPMMALAQQFANVDYEVLLYDPKSSENRRGEFVANLVKESGAQGLVLFMQQFCDPE
                     EMEYPYLKKALQAADVPHIKLGIDQQMRDFGQARTAIQAFADVLEMRK"
     gene            complement(41206..42642)
                     /gene="hgdA"
                     /locus_tag="ACZPCR_05245"
     CDS             complement(41206..42642)
                     /gene="hgdA"
                     /locus_tag="ACZPCR_05245"
                     /EC_number="4.2.1.167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501726.1"
                     /note="The alpha subunit (HgdA) and beta subunit (HgdB)
                     together are called component D of
                     (R)-2-hydroxyglutaryl-CoA dehydratase, a key enzyme for
                     glutamate fermentation. This oxygen-sensitive enzyme can
                     perform a large number of turnovers after activation by
                     HgdC, which requires a hydrolysis of ATP and transfers a
                     single electron to the dehydratase; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyglutaryl-CoA dehydratase subunit
                     alpha"
                     /protein_id="HIR1230314.1"
                     /translation="MAKQVSPGVLALRKVVDDVHKEAREAKARGELVGWSSSKFPCEL
                     AAAFDLHVMYPENQAAGIAANRYGEMMCQAAEDLGYDNDICGYCRISLAYAAGIRVSR
                     KYDPETGEYIIDPSTGKPLKDADGNVVMGEDGKPVKDPKTQTPYLQLDNLLEIEKLPD
                     GPEKERRLEAISPIRQMRIPQPDFVLCCNNICNCMTKWYENIARMCNIPLIMVDIPYN
                     NDVHVADENVKYVRAQFDKAIKQLEELTGKKFDEKKFEQACANANRTAKAWLKVCDYL
                     QYKPAPYSGFDLFNHMADVVTARARVETAEAFELLAKDLEETVKKGETTTPFPEKYRV
                     MFEGIPCWPKLPALFKPLKANGVNVTAVVYAPAFGFVYDGMDEMARAYYKAPNSVCIE
                     QGVDWREGICRDNKVDGVLVHYNRSCKPWSGYMAEMQRRFTDDLGVPCAGFDGDQADP
                     RNFNAAQYETRVQGLVEAMEANKQAKEA"
     gene            complement(42673..43461)
                     /gene="hgdC"
                     /locus_tag="ACZPCR_05250"
     CDS             complement(42673..43461)
                     /gene="hgdC"
                     /locus_tag="ACZPCR_05250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyglutaryl-CoA dehydratase activase
                     HgdC"
                     /protein_id="HIR1230315.1"
                     /translation="MAIYTMGIDVGSTASKCIILKDGTEIVGKSLVDVGTGTSGPARA
                     IEEVLADAGMTKDQLDYTLATGYGRNSLSDIAKKQMSELSCHAKGASFLFPKVHTVID
                     IGGQDVKVLHIDNGAMTNFQMNDKCAAGTGRFLDVMARVLEVKVEDLGRLGAMSKKEI
                     GISSTCTVFAESEVISQLAMGTDKCDIINGIHKSVAHRVTGLAHRIGVVPDVVMTGGV
                     AQNSGVVNALQQELGCEIHISPLTQYNGALGAALYAYQAATRQK"
     gene            complement(43772..>44599)
                     /locus_tag="ACZPCR_05255"
     CDS             complement(43772..>44599)
                     /locus_tag="ACZPCR_05255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="HIR1230316.1"
                     /translation="SIVPMNQKRPYDMYEVIARLFDNSEFAEYKKGYGPEMITGLAKV
                     NGLLVGVVANVQGLLMNYPEYKQNSVGIGGKLYRQGLIKMNEFVTLCARDRIPLIWLQ
                     DTTGIDVGDEAEKAELLGLGQSLIYSIENSKLPSLEVTIRKASAAAHYVLGGPQGNNT
                     NVFSLGTGACEYYVMPGETAANAMYSRKLVKAKKAGEPLQPIIDKMNDMINMYTEKSR
                     PKYCTKTGMVDEIVDMTDIRPYIQAFTEAAYQNPQSICPFHQMITPRAIREFETFKK"
BASE COUNT         9668 a        12724 c        10021 g        12186 t
ORIGIN      
        1 aatccagata ccatcagttc catcacagtc accctttcca gcttaaaact ctatgcgttt
       61 catttccgtg tttttagtat tatattcccg ttcctgttcc gtattccccg aatccttctt
      121 ctctcctggc cgggccatac ggcatatctg tccggaaata aagttagttt tttctaactg
      181 ttattaagtt agcacatgct aacccatttg tcaactattt ttcgctgtgt ttttctttta
      241 tgtttttctt tccctgttta gattcggctg actttttacc atatttttga tataatggac
      301 agcgtcagga tacaaagggc aatgtccctt gcactgacgc cagtaaggaa tagtaacaaa
      361 ggagagggta tattgaaaat ccagcagtca gcagaggact atcttgagac gattctggtt
      421 ttaagccgca aaaagtccca gattcgttcc attgatatcg tcaatgaatt gggctactca
      481 aagcccagcg tcagcgtagc catgaaaaac cttcgtgaaa atggatatat ctccatggac
      541 cgggacggct atatcacgct ggaagaaccg ggactcagaa ttgccgagac catttatgag
      601 cgtcacacct ttctgacagg atttcttgtc tgtctggggg taagtcctga gacggcggct
      661 gaggacgcct gccgtatgga gcacgtgatc agtccggaaa gttttcaggc catgaagcgt
      721 ttcgctgaaa aaaatctaaa agagcaggat gtgcggtaaa cgatctgaaa agagagaagc
      781 ttccggccaa aacaggcgtg ggaatcttct ctcttttctt tttctatttt ctattttttc
      841 aattacatgc agcgtttctc aagaatgtcc gcaagggcgc tctggctgct ggtgtggcag
      901 cgcaccacct ccgttctggt tccccgcgct ccctccacag ctgcccgcac cattttatgg
      961 gacactgtgt tcgtaaacag aaccagcaga tctggacttc ctacctgttt tccgaattcg
     1021 gcgctcatct gggtaaatac ctttgcttta catttaaaat ttctgcagat ctgtttatac
     1081 tggctgacca ttctgtcatg tccgcctacg atcacaacac tcatgtgcct ctcccttctc
     1141 tattttatga ttccgccagc tgtcttccca gttccttcaa cgcttcctct gcactggcat
     1201 ccggcgctcc gcagcagatg gcgtcctcgc cgcccagcac ataggcccct gcctgcttca
     1261 tccggtcgct ccagtctctc atccactgac cgtctcccca gccgtaggaa ccgaacaggc
     1321 cgatggtctt tcctgaaacg tttttttcag ccgcctccac aaacggctcc attacgctct
     1381 cctccagcgt ctcatccccc atagacgggc atccaaaagc tgctgcctgg aaggaagaca
     1441 gctgttctgc tgcggcttcc tccgcaggaa taagaaccgg ctcttttcca gcctccctga
     1501 tgccggacgc taccatctcc gccatagccg ccgtatttcc tgttccgctc cagtaaacaa
     1561 ttaaaatctg attcattttc gtatttcctc ctgataattt ttttctgttc agactgctct
     1621 cagacacaga ccgcctgctt taagccgccg ccgtgaggct gtaaaccggc tgtcccagaa
     1681 gggacgcgca gatctgcccc aggctttttc cccgctccgc ttccttcacc acccgctctc
     1741 tgaccgccgt ataaactgcg aagcgttttc tggcttcctc cggctcccgg tataccttcc
     1801 agtagccgga aaaaagaaag tctctccctt tatgctcgat aaatcccttc acatcccaga
     1861 tgggatattc tagtatcagg ccgatttcat ggggaaattc tccttttccc tctgcataaa
     1921 gcccgtaccg cgccgccagc cctgaaagcg ccttcgaaag ctccatagag ctgtagccaa
     1981 agccctgaaa aaagcttctg gtctccctgc ttttaagaat cttttctgtc tgctctctcc
     2041 ggtacagaag atagacagtt cgtccctccc ctgcccagag acatttgcag tcaactcccg
     2101 ttccgcggag gacaaaggcc acgtcctcct ctgttccctc tgttgtaatt aatatattgg
     2161 aggccttcac gccggccagc acctgcgcgc agtgaaacgc cgcctgcttc tgaattgcat
     2221 tctgctctct gctgtataac ctctgatcca tccgctgtcc tccctgctct ttgcttttca
     2281 tttattttcc cttaatctgt ctgtcgctgt ttctttaatt tgtttggtta gtcttatcta
     2341 actcatgcag ttagtataca ctaacccatg ccttttgtcc agcacttttt atttttttca
     2401 aaaaaagaag cgcttcctct gtaccagcca gaaacgcttc tcttctttat tccatatcca
     2461 gttatgattt tcctgccccg gccagcactt cctccatctg gcccttcagg gtccggccat
     2521 aaatgcggtt aatggcgctc tccgcctttt tgcgcagccg ttcctgttct tcagggctgg
     2581 ccccggccat ctggtcaatg tatttctgcg cctcgtctgc cagcgcgtga tctctcctgt
     2641 aatcgcctac cgtataattg ggggagagga catgggaatc gtcatagccc tccaggtact
     2701 ccccccgccc ctccttttta atatcttcct tctccgcttc cggcgccgca aaagccgctt
     2761 ccggaagacc tgccgtcagt ccctccatgg cctgcttcca gatagaggcc ggataggagg
     2821 aaccgtagag agaggagaga gtccgtgggg tgtcgtagcc aacccacacg gtcactgtgt
     2881 agtaaggcgt cattccgcag aaccagccgt ccttgctgtt gttggtggtt cccgtctttc
     2941 cggccgcctc aatcccgctc ttccagccca ttccccgggc ggttcccctc gatataacgc
     3001 ccttcataac gtctaccatc acggccgccg tctgctggga ataaacctcc ttcggctccc
     3061 ttcctgtgta gatgtcttcc ccggccagat tctccattct gacaatacag tccggttccc
     3121 ggtacacgcc tccgttttcc agggcgctga aggcgccggc catctcctct gccgtcacgc
     3181 cgtaggtaaa gcctcccagg gaagccgcca tattgtaatc gtccggcaca attttatcaa
     3241 actgcatctg agtcaggtag gagaggccct cctccggcgt cacctcatta aacagccacc
     3301 aggccgctcc gttccggctc ttctctaccg cctggcgcag ggtaatccag ttgcccggaa
     3361 gggaggccac atccgccttc ggctccttcg cagcgtccac gtttatatcc ttcacgctgg
     3421 aaaatgaagc gtagccctct tccagagccg gagcgtagac aatcagaggc ttaatgctgc
     3481 tgcccggctg gcggaagctc tgaaaggctc ggttcagggt ataggtgctg gtctcctggc
     3541 ttctgcctcc cacaatggcc tccaccaggc cggtatcgtt attgacagcc actgccgcgc
     3601 cctgcagcgc gtaaatgccg ttgtccgccg tctccgcgtc aaaggagagc acctgatcca
     3661 ccgcgctctg caggatttcc tgcttggccg gatccaggga agtataaatc ctgtagccgc
     3721 ccgtatacag ctcatcctta gccgcagcgt agctttcctc gtaggctgcc tggtaagact
     3781 tgtaatcgtc gtagctggaa aatccatact caaacgaaaa tccctccctc tccatcagcc
     3841 agcgcaccgc gcagtcgatg gcataggtcg tctcataatt ccgcatctcg taggaatttc
     3901 ctgtcaccgt gatctcctca gccaccgccg cgtcatgctc ctcctgggta atgtaaccca
     3961 tggtcagcat gtctccgaga atcttatctc tccttgtcag ggcatgatcc ggatggcgat
     4021 acggattata gtaggacggc gagtttggga tcgcgcacag ataggcgatc tggcttaagc
     4081 tcagctcgtc tgcatccttt ccgaaatatc ccttggcagc cgcctgcaga ccgtaatatg
     4141 tattggcgta attgatgtca ttgacataaa attccatgat ctgttcctta gagtacttct
     4201 ctgtcagatc catggcaatc aggatttcct tcaccttgcg cttgatggac acgtctctgg
     4261 tcagataccg gtttctggct aactgctggg taatcgtgct ggccccgtgg acctcctctc
     4321 cctttgtgag aataaaatta attcccaccc ggagaatccc cttaaagtct acgccgcagt
     4381 tctcccagaa ggttctgtcc tcaatagcaa taaacgcgtt caccgcatcc tgtggaattt
     4441 cctcataggg aaggtactgg gagtcctcat cccctgaaat cttggccagc acattgccat
     4501 ttacgtcgta gaaataggac gcctggcccg gcagaaaatc tgcctccgtg ctgtttgcca
     4561 ccagtccgtc cacctcttct ttgcagatgg tgtaaaactt ccatcccaga aaaccgcagc
     4621 ctgcggcagc cacaaagagg atcagaagaa acatcagaaa gaaccgcttc cacagccgcc
     4681 tccagccctt tttctgtctg gcagggcggc gtctgcgtcc agcctcttcc tctgtccttg
     4741 cagctggttc ccaacttaac ggatccggtc cggcggcctt ttgctgtctg gcgccttcct
     4801 gctccccggt ctcttcctcc agaatgctct gaatctgttc gcccagctcc tgctgcacgg
     4861 cttcctctgc ccttctctcc tgaagccgtt tcgcttcctt cctgtcctgt ctcttctgcg
     4921 cgtctgccgg ccccggcgtc ttctgcccct gccggcccct ggtgtgcccg cgttcatttc
     4981 tctctctatc catgttactc ctttttctgc ctgtaccagt ttcgtccgtg catcgtcttc
     5041 tcctgccctc ttgttctcaa acccatattc tgtgagaggg gcagagcttt tgtctatttt
     5101 accgcgtttt cctccataat acaacctgtt tgcagttccc tgcacgacaa acgccaaaaa
     5161 tgcggctatc tgcgcagcag tacggctatt tcatggacga ttacgggagc ggccgccaaa
     5221 ggcagaagaa atccccattc tgacagggaa aggacgcagg ttccaaaagc ctgtgtcaga
     5281 gccggaatct ctgtcaccgc agcctggaga agcattccca gtccgaaggc cagaagcatc
     5341 agccggttgg agcacaggcg ggatccaaag actgaagaag aaacgtcccg catccccact
     5401 gcgtgaaaca gctgggaaag gctcagcacg gtaaaagcgt aggtctggga ttttaataaa
     5461 acctccggat tctgcagaca ttccctgact gacgaaagct ccatggaacc agccagctcc
     5521 atgggaagcc ggaaaaatgc cgtgaggctg actgctgcaa tcagaaaacc gtatcccagg
     5581 gtgacgaacc atcctccgcc tgcaaacaga ctttctccag actgtctcgg tggcttctcc
     5641 atcagacgcc tgccgtcatt ttcatccact cccagagcca gggcaggaag cgaatctgtg
     5701 atcagattga tccacaaaat gtggctgggc tttaagggag aggccacccc ggccgcaatc
     5761 gctgcaaaca tggtggcaat ttccccgaaa ttggaggaca gcagaaaaat tactgatttt
     5821 ttaatattct cgtaaacgcc acgcccctcc tccatggctc tctcaatggt ggcgaaatta
     5881 tcgtctgtca gaatcatatc ggccgcctgc ttggccacgt cggttcccgt ctttcccata
     5941 gcgattccaa tgtctgcgtt tttcagggag ggcgcgtcgt tgactccgtc tcccgtcatg
     6001 gccgtgatgt ggcccgccgc cttaaaggcg tttacaattc tcaccttgtg gccaggggac
     6061 actctggcaa atacctttaa atgctttatt tttttcttca gctcgtcgtc ctctgtccgc
     6121 tccagctcct cccccgtcat gcactgagtc ctgtcctctg caattcccag ctcttttgca
     6181 atagccagag ccgtgtccac atgatcccct gtaatcatga cggtatccac cgacgccttc
     6241 cgaaactgcc cgaccgcctg tttcgcctcg tctctgggcg gatccatcat gccggccagt
     6301 cccaggaagg taagcccctt ttcctccggt cctgcggcat cctccttcgc tgccgcggcc
     6361 agcacccgaa gcgcctggga ggacatcctt gcggctgcct gctccgcttc cctgcgctct
     6421 gcctcagtca tgggaaccga gcggtggttt ttccagatat gtgtacactg cctgagcacg
     6481 cggtccggcg cgcctttggt gcaggaaatg cctgtctttc cctgtctgtg gaaggtcgtc
     6541 atcattttcc ggtccgagtc aaagggaagc tctccttttc tgggcatttc tctctccatc
     6601 tcctcctttt caacgtctgc caggctggca aactggagaa gggccagctc ggtcggatct
     6661 cctttttcct gctctaaccg ggcgtcgctg cacaaggcga agcactctgc caggcgtttt
     6721 gagggttttt ccgccgctgc gttttccagc gtcctgattg tcccgtcctc ataccactgc
     6781 gttacggtca tcacattttt agtcagggtt cccgttttgt ctgtacacac tacgctgaca
     6841 gctcccagcg tttccactga cggcagtttt ctcacaatag ttcccgcctt aaccatcctg
     6901 gtaacgctta aagccagcac aatggtgact actgccggaa gtccctccgg cacggcggct
     6961 actgccagcg atatggcggt gataagcatt tccataacgt cccgcttctg aatcaccgcc
     7021 atgagaaaaa gagcggcgca cagggctacc gccgtcagac tgagcacctt tcccagttct
     7081 cccagacgtt tctgaagagg cgtctcttcc tccggcgccg cgtgaatcat ggccgcaatc
     7141 cttccgatct ccgttcccat ccccgtggct gttacaatcc cttttccgcg gcccgaggtc
     7201 acataggatg tcatataggc catatttttc ccttttccgg atccgtttcc ggttccggac
     7261 tctgacgcca gataatcagc ggacttggac acaggaaccg actctcccgt cagggctgat
     7321 tcctcaattt taaggcctgc cgactgaatc aggcgcatat cggccggaac ctggcagccg
     7381 gctgtcagaa gcgccaggtc gcctggaacc agctccttgg cgtcaatttc tatctccctg
     7441 ccgtccctga cgacggatgc cttcaggcgg gtcatctgct ttaaggaatc cagagccttc
     7501 tgcgcttttc cctcctgcac tacccccaca atgccgttta cagctaccac aatcatgata
     7561 atcactgcgt cactgtactc ccccagaagc acggaaatcc cggccgctgc aaacagcacg
     7621 aaaataagag agtcgcagag ctgcccggca aaccgtttca gaagcgtttt ctgctttttc
     7681 tcctccagct cattgcttcc atagtgtttc tgccgctctt ttacgtcctc ctccctcagc
     7741 ccccgctctc cgtcagcgct cagtttcttt aacgtctcgt ctatggtttt tccttcatac
     7801 atgaatgttc cctcctttgg acagccgttt tgccttttga cactttatga agggcagaat
     7861 tgttttagaa ctgcggggaa gatcggaaaa gagccgccgg gaagcaggtg aatctgcacc
     7921 ttgcttccca gcggctctgt ttctctttct atgccatttt ctatcgtttc cagatccgga
     7981 cttaagaaag tcctggacct gacggctttt caggattgat ctgaacgatt ccgttaaccg
     8041 tccactgccc ctgagcattt actgtatagc cgtccggtgt ctttccgttc tttaccatgg
     8101 agcctgcagg ctgtccctct gccgaatcct tggtgaagta atagcagttg tctccaatcc
     8161 agcgccatcc cgtatacatt gctccgatct tggcgtcgtt ctggtcatga aagaaatagg
     8221 tatggccgtc cttatctgta aaccagcctg tctccatata gccttctgcg ttgaaatggt
     8281 accagccttt ctttccgttc caggagcact cgaaccagcc gtctgccgga tagcttccgt
     8341 ccagctttgc gaaccaccag cctctgccgt cctgcttcca ggagccgttg ggcttttctg
     8401 tccactcaga cctggagttt ccacgtccgc tgtttctgtc tgaatcgtcg tcctctgtgt
     8461 cctcatccgg agtatctgga gcctctggtt caggagtttc cggatcctcc gtctctggct
     8521 cttccggttc cggcgtctcc agaatcatct cataatcctc gtactcgccg aagtttgtca
     8581 cctccagctt ctcatggaag ctgttcacgc cctggaaatc atctctgtcc acagaaatcc
     8641 tcacattttc ctcggaatcc actgtgatgg ttcccagatc cagctcctcg cccttttcca
     8701 gtaccggatc gcgatccgcc acatagacag tcatctcctg ggcgtcctcg tcgtaccgtg
     8761 tctcgtacac agctggatcc aattttgact ttatgttctg tgaaaactta aacgccggat
     8821 cctcagacat cggctcgtcg ctttcaaata taagcttcaa gctgaaggct gtaaagctgt
     8881 cggccggttc ctggtcctga agcttaagtt tcagcctgac cgaatttttt cctgtttttt
     8941 cccaggtgat catctggttt ctttccgcca tggaatgcat ggacggaagg agcgccaggc
     9001 tgagcgccga agcgcacaga ccggctgcaa atgtcgtctt tttcattcgt ccttctttct
     9061 ctccttattt tatgcggctg ccctacggct taatttcaat gtccggaaga tttttcggca
     9121 gctccacaaa cagcgtgtcg ctgacaagac gatctccctc gtttgtctct gcattgtcga
     9181 cgcggtacat ctccgcgcgg accttaccag gaagcgttac gccgtccagc tcatccggct
     9241 cgatgtagta cacccagatt ccgtctgtga tctcgcccag ctgtccgttc accggatccg
     9301 gggcaaaaat cagctgatgg gctgtgactg cgccgtctgc gtctcttccg cccactacgt
     9361 ttccatcctc gtcatagaga ataaatgtgt tgtaggctgg atttcctttg tattttccag
     9421 taaagatcac agaacctgcc ggaatcttgt ctgcagtctc ttctcctgtc tctccggaac
     9481 ctgcgtcagt taaatagaaa tcttccttca ggattccgat tccagcctcc gctaactcca
     9541 cattgtcgcc ggtcgggccg agaatatcaa gctccgctgc cgcaaagctc ttggatcctg
     9601 cggctgtaat ctttaagtaa gccgtctcgt acacatggta gcgcggatcg tccttcaggt
     9661 caaagtaaat gagagcagaa ctgcttccct cctggaattc aaaggttccg gacttaatct
     9721 ccgtccactt ctctccgtcc tggctgatgg aaagcctgta atttttcact ggattctctc
     9781 cgtcgtaggt gtacttaaat cctgcgatgg actctgtttt tccaagagaa atcactgcct
     9841 cagcttcctt ctctgtggta gttcccacat acgcctgatc cagctgattg tcaatcatca
     9901 tgccggcggc gctgatggtt ccggagcacg gagtatcggt ctcgtcctca ttgtccggct
     9961 tctcatcgct tggagaggtg gtgttgacgg tgatctccca gtctgtctta tctaacattc
    10021 cctcgtgtaa gagcttgaac tcatcggaaa tccggtaagt ctctgtcgga ttcatgcact
    10081 ggtcaatacc ccgcatctcg taggatacga ctctgttgtt cgtcgtcatc acatgatccg
    10141 taaaggtatc gctggtggta aagccaacca cccgtctctc ttcctttccg tatctgcgct
    10201 cgattctggt aatctcatag cccagaagct gatcccgttt tccctcgtcg ctgaggctca
    10261 tggtgagatg cacctggttg gaggcctgag aatccttctc tgcctctgcc ttcactgtga
    10321 cagattcggc aatgctctct ccgccttcca gacggtatac tctggaatcg tcgttctcat
    10381 agtaaatagc gcgtgtttcc tcgtcaaact gtccggcgta ctcgtctgtc gtcttgtcag
    10441 gcgtcagtcc ccagcgaatg aagaagtctc ttaaatcctt ctctgccgcc gcgcaggcca
    10501 gacggatcat cttgttgtcc ttatccgcgt tgtcaagcgt cagcttaatg ccgcccggcg
    10561 caggagcgcg gcttgtatct ctcgcatagg agtcaatcct tgcaaagatc agattttctc
    10621 tctgatcctt ataattgtcg tatgtcttaa agttgtatcc tccgttgtcg taggccatat
    10681 gcagctgcca gtacatagcc aggcgctcgc tgccgcctcc cttggttccg gaggttacct
    10741 tcttatatac gtcctcgtaa gaaaatcttg tggtatcgtt gctgtcccgg gacttggcca
    10801 gctgcgggta gtagttgttt gtcgtctccg cgtaggcgta tgctccctca ttgataatgt
    10861 ggccaatctc gtgggaaatt ccccagccga agtactggcc gtcctggttt tctaaggctt
    10921 ttccgttttc gtcggtctca atcggcttgg aaccgcccag agcaggtacg gatccccact
    10981 caataccaat gtgcagtccg cctgcgtaca tgaacgcgcc ggcaaacata cgctggtagc
    11041 ggatgttgag acggctggta ggcgttctgt ccttgccgta ggtcactccg tccatcaccg
    11101 gattgtcgct cagtcccttg tgctgataat ataagtctat catggcgtcc atagcgttca
    11161 gggaatctgt cagctgctgg acggcgtcct ccttcttgtc agagcgtttt gtcagctcgt
    11221 catagagagg cttaatggct acggaataca tcatctgatc cagaacgata tccgttgctc
    11281 ccaggataca gttcttctcg tcgtattcct tgcctgaaat atgcctgtga gaagtctcgc
    11341 tgtccggatc cgcgttgtga agcgcttcca gttccttcac ccgctcctcc atctcagtga
    11401 aataagtttc aatcagctgg gctctctcat cctcgttctc agccttagtc aggtcaagca
    11461 ctgggtaagg tgaaccgccg ctgacgcgga ctgcgtagga atcatttata tttcttccag
    11521 tgtactccac atagagggcg ccgccctgct cgcagtcaat gctggaaatc ttcggaatga
    11581 tgatctcgtt gacgcctacc ttcagatctg acgcatattt gtagaacgga gaggattcgc
    11641 tgtggtactg ggttgcaacc agctttaacg gagtgctgtc tccctgagtc tttcctggcg
    11701 cgcctacata gatcgtcacc ttctcgcctg ccagagccgc tgtacccaga ggctgccatg
    11761 cgttcaggcc tcccaggaag gtaatatggc tgtcatagga tttggataca gaggtatcga
    11821 tctgaaccgc ttcctggctt acgcctgtca gcagaatact ctcagccaca ctcagatcct
    11881 ttaaagccag ctccttcttc ggatgcgtct cgccgctggc cggatcaagt tcattagctc
    11941 tctccttcag cgccttgacg tcgtccatcg ttacctctgc cttcaatgct acatggagag
    12001 cgtctgtaaa cagcgcgtca atatcgttta aaaggctgtt gtattcatag aagcggatct
    12061 cgccgatact gatatatctg acatttccgc tggcgctcag attgatctga accttttttg
    12121 ctgtaaacgg ctcgctggca ataaattcgt agtacacgct accattgttg tccatactgg
    12181 caagtcgtga aaaacgtcct ggaatctctt ttccgcttcc tgaaccatcc tcagtctccc
    12241 atgcaagcac cttgattgca cttaaatcag atttctgagc cggccctgcc gtaaagcgga
    12301 tggtatccat ctcataaggc tggtctagtg tgataatcgg acctctggaa ccgtaatgca
    12361 cgccggaatc ccagtcctcc agcagccagt agctggtggg atctccgtcc acgattactg
    12421 tcggaatggc gatttcctca tctgctctgt tatagtttgc tccttctata ttctcaacct
    12481 ttttaatgtg gtttgtcaca tccttgccct tgtccgggcc gtcattgagc aggccgtagg
    12541 cgggcatctt agctgtagcc gccggagctg tccttccgga atacatcgtg gaatcagggc
    12601 tgtctcccag cggattgtgg cctaccatgt aaacctcata ttccgtgttg tctgccaggt
    12661 gctctaaagt gaggctggtc tggcttctgt cgatattctc caccgctgtg aactcctcgg
    12721 ttcccttctg gcggtagaac agcgtgtagg actgcgtatc cttcatcttc ttccaggata
    12781 cgttcagaca gcggtaaaaa ccgtcgatct taatgtattc cggcgctggc ggcggaccgc
    12841 ttggctccgg cgtcacagac agctcgctgc tgtaattgct cttccaggtt ccgttgacag
    12901 aacgcactct tacccggtag gtctcatagt ttaacagctt ctttccgccg aagctgttga
    12961 tcgtaacaga attctcctcg gaagccatgg tctctgtctc tccgtcatga gaaatagaaa
    13021 tctcgtagcc ggttacgtta ttctccttgt cccagatcag ggtaaactct gcgcttccaa
    13081 tctctgcctg cagattcttc ggaatattct gcactggcgg cggaatgcgg tccttcatgt
    13141 cctccataaa ttccacctgg ctgatctccg ccaggcttcc ctggcttacc gttccggtta
    13201 cgcggatcgt caccttcttc accggcttct ggctctttaa attgactacg atggagccgt
    13261 ccggctgaat ctctgccgta ccgccgcttc ttccgaagcg ggcctttctg gcctctccgg
    13321 cttttacaat ggtgagcgtc tctttcttct cttttccatc gtcgtccacc gtcacttcta
    13381 tttctccgct ggtgatggcg ttctccgatc cggacggaga ctggataaca aatccctctg
    13441 ccttcagctc tgtctcgctg tgggtgaagt ccagagtcag ctcaacagga ttttcctcag
    13501 agatcttctc tccgtctttt cttgccacag tgacagacga ctcctcgctg tcatggtcaa
    13561 agagcgcttc cggctttccg tcgatctcca ccgcgtcgct gggacttgca gtgtcgtcaa
    13621 actttacctc tccctccttg cgggttacag accgctccac tgtggaaata tgcttgcggc
    13681 tgctggaatc ataatcgtaa aagcttgcga aatactgaag gtcagacagg ttcagctccc
    13741 catcctgatt gaagtccatc gcgtttacgc ctggctcctc tgcgtggatg gcgtccagaa
    13801 gctcctccag atcctcgtcg tcgatgatat cgtcgccgtt cacatctccc attcgaatca
    13861 agcctgggtg ggcgctggaa gtatactgct cctcgtcgta ataatcatta aacagcatga
    13921 ctttgcaggt atcccccttg attttaatct cctgcttata aggctcatac ccttctgcgt
    13981 ttactgtcag cacgtacgtc ccgtccggta cataattgga ctggaacact ccctttccaa
    14041 tctcagacat ctctccgggc tgaacggtga actgaccgta ctcgttcact tctgcttcct
    14101 gtctgaggaa ttttgccagc ttagacggct tctctgtgag atgaacctca aacgggatct
    14161 ctccctccac agggagcacc gtgcggatct ccacgatcac attgccgcgg tacgggttct
    14221 ccagcggagc gtcaggcgtt gcctcaggca gggtttccgt ctcctcttcc tgtccgtttg
    14281 aaggactgga tacgggaagc cattcactct gactgccgcc tgtcactcct gctgccaatg
    14341 gctgggccgc gtaggcctcc agcgtgccga ggggctgctg cagtccaatc caggcagcca
    14401 gcacaaatgc cagttgtcgt ttcatgtttt gcttctccta ctctcttgta tttttgggct
    14461 taaaagcggt ttattatacc agttttttct tatttgcaca aggaaaaatc cggagaaaaa
    14521 cgagaagaat tcctgaaaag aacaggtgga atcgaaaaaa aagaagaaaa gaaacttcct
    14581 gctgtttaaa attgaaacag gaattcttct tttcttcttc tctctatctg cttatttcgc
    14641 ctgtattatg catcctcggc gctgatctcg tacgcgccgt cctttctctc cacaacccag
    14701 accgtgccgc cgtcccggta tcgtccagga ctctggattt ctccggaacg gtttaccaga
    14761 taatccttat cgtctaccgt cctgatctca tattttccta cgtcttccgc tctctgcagc
    14821 gctccggccc ggtagagctt cccctgatgg gggccgtgaa ccgcttttcc gcttccgtgg
    14881 aattcaaatg tgcaggtttc gccctttgac acaagttcca cagttcccgt ccgtctggct
    14941 ccgctcccct cgtcgaaata catcagatca tactcttcca gatagttttc cagatcttcc
    15001 acgctgcagt ctgtactgtc tcctgcacaa atcaaggttt ccgcatattt tttgtctttg
    15061 gtcacagcca ccaggccagt ccgcataatt cctgcctggt cgaacagata ctccttcccc
    15121 cgatgtttct catccggttc tgaactaccg ttccgtcgga aagtccgtaa taccatcttt
    15181 ttatatggtt ctcgctggca taagaatcct gcgacgcttt tggaacccgc tcaatccact
    15241 gttctgtcag cgtgtttgga ctgcttccca gctttttcga ggaccgcatc attccattct
    15301 cgtcgaaggt atagcggtat ctcccgtttt catcgctttc cgtgatgctg gtatccgccg
    15361 ccttctttcc attaggatag aagtaaaacc agcgctgttc cctgcctccg ttctctctct
    15421 ggacaggaag gcagcgccat cccgccgcag tcacgtcata tacaaagtct gtcagcacgt
    15481 aaaccggcat aatgacctta tcggactgat ctccgctgcc gcttccgtcg ccagtagatc
    15541 tggatgctcc tgtttttccg gcttctccag tctcgccctc agcgcctgcc tctccggcct
    15601 ggcccgaatc tctgaaaagt acagactgac ttcctcattc tgcacaatac tgcggttttc
    15661 cagatcaagt tccgtcccgt cggccaggcg catcctgctg cctgacgcca gaacctggaa
    15721 cgctgtctcg ccgcctgaaa tacgcacgat tcctctgtca atatacgcaa gctccgcgta
    15781 gcccttcagg ctctcctctg ttccgtccgg aaatgtaagg ctgatctccg gagaggagac
    15841 cagatacttc tcctcctgca ttttccagat atagtcctgg aattccagag gcgttccctg
    15901 gttgtccagc agatatttgt ccccctggcg gttcataaca gactcggctc ccaggctgta
    15961 gtaatttaaa agccccttct tcagctcatt gcactctaca atcacgcctt tgtggaacgt
    16021 gctgatggaa tcgtctgcat agtggataaa actgtctgca ggaacctcct gtttcttccc
    16081 gtacatatcc ttgaagctga tatttccgga ataattctcc ttgtaccggg ttcccgcttt
    16141 aaaatacagc ggttcgggaa caaccgatcc gttcttcccg ttttggtatg acagcacgta
    16201 gccatccccc cagaaggcct ccgcattttg gacatggcgg gaaatcccga atgccgccgc
    16261 gcctcctgca atcagcagta ccagaatcat actgacagta taaattttct tactcatttg
    16321 tcctcccctt atttcaagct gctatggatg aactgttttt acacacggaa acaaacagac
    16381 cgtcattctc tcctgtctgt ctgcctgtaa ctagtatttt tataaagaaa cactgcattt
    16441 tttgcgttta ttttattccc aaaagatgtc aaaaatcaat aatgttttcc aatatttctc
    16501 aaaaaagaca aaaaatcccc tgcgggccgt taaattaaca gtccgcaggg gatatgtctt
    16561 cttatatcag cgtcttacag cgcaaaatct ttttttattc agcagtctct gccgcctcgc
    16621 ctactgtgcc gtacatgaag taccagtagc cgtatggaga atgccaagtt ccctgaagct
    16681 caggcttctg taaccagaaa tcgttctggt atgcaatcgg aatcatggcc atatcgttta
    16741 acagcagctg ctctgcctca tggagaagct tgtagtgctc ttccttatct gccgtcattc
    16801 ttgcatttgc gatcatctcg tcatactctg gattgctgta cttaccgtca ttgtttccat
    16861 tctctgtctc aaacaggttc agcatgttgg atggatcatc gtaatcatat acccagccat
    16921 ttctggcaat atcaaagtca ccgtttcttc tggttggtgt gaaagttgcc cactcaacca
    16981 ccttgatatc catagtaatt ccaagctcgc cccatgcact ctgcagatac tctgccagag
    17041 gcttatgata gcctgcgtca tttgtcatat actcgatggc cgggaatccc tctccattcg
    17101 gatagcctgc atctgccaga agctcttttg ccttagccaa atcgccctca aagtcatctg
    17161 tatggaagaa ctcaccgttc tctgcgatag tcacttctgc gaaggaagaa cctggctcta
    17221 catcggaaac gcctggccct acgaaattag tagccgggga atatgttccc tgcatgatag
    17281 tgtccgcaat ataagcgcgg tcaagagcaa ggcttaatgc ctggcgtacc tttacatcct
    17341 taaaatagtc tctgtttaag ttcaggctga tgtagtaggt tccaagaagc ggatctacat
    17401 ggaactcagg gttctctctg aggttcggaa cctcctcagt cggaacgtcc ttaatgaaca
    17461 taacctcgcc tgcgttgtat gcgctgtagg ctgcgttcat gtcctccatc aggacaaact
    17521 tgatggtatc tgctgttacg gcgtctgcgt tccagtagtt ctcgttcttc tccatcagga
    17581 tgtgggagcc tggcacccac tctttgatct tcatggaacc gttgcagatg taggtagacg
    17641 gatcaatcgc ccaggactcg ccgtttgctt cgatggtagc ctggttgacc gggctgagag
    17701 ttgcaaacgc acaaatctta tcaaagtata cgcatgggta ggaaagctct accacaaagg
    17761 tctgatcgtc aggagctgat actgctaacg catccagatc tcctgctgcc gcctcatcgt
    17821 agccctttac catgcacaga aggtcatagc cataaggagc tgctgtcagc ggatctgcca
    17881 cacgcttgaa tgtatatacg aaatcatttg ctgtcagcgg tgtaccatca ctccacttta
    17941 atccgtctct taagtggaac gtataagtga ggccgtcctc ggaaacctcc caggtctctg
    18001 ccataccgcc gatgatattg ttatccttgt caaagtttaa cagcggctca aataagtgaa
    18061 taatcatgtt ggctccgtcg atggcgctgt ttaacgccgg atcgatggtc tcaggatccg
    18121 ggccaatctc tactaccaga ttatttccgc cctctcctgt ctgtgctgcc tgtccgtcct
    18181 cgctggccgc aggctttgtc tcctcagagc cgcctccgcc gcagccggtt aaaacggttg
    18241 tggaaagcat tgccgctgct aacataagcg caaatttctt tttcataaca ttctcctcct
    18301 tgagattttt ttgaaaagcg cacagccaga cgccggcgct caacctcttt ttcactgtcc
    18361 tttggtaaag cacgaaacag aaaagatagt tcaataatac cacagaatca aaaatatgca
    18421 agaacttttt tattaataca tctatttttt gccgcaaatg ctaaaccgtc aaaaaaaggc
    18481 ccgggattct gttttcccag accttttttt gtatattgtt tactttcagc agaaaatttt
    18541 aattattttc acactttact tcgtttcctc tggggactca gcctctccta cgctgccgta
    18601 catgaagtac cagtagccgt acggagtgtg gtaggttccc tgaagctccg gcttctgcag
    18661 ccagaactcg ttctgccatg caatcggaat catggccata tcctctaaca gcatctgctc
    18721 tgcctcgtga agcagcctgt aatgctcctc gcggtcagcc gtcttgcggg ctgtctctgt
    18781 ctttgtgtcg tactccggat tgctgtactt tccgtcattg tttccgtttt ccgtctcaaa
    18841 cagattcaac aggttggatg gatcgtcgta gtcgtaaatc cagccgtttc tggcgatgtc
    18901 gtaatctcca ttgcggcggg tcggggtaaa ggtcgcccac tccacaatct tgatgtccat
    18961 attgattccc aaatctcccc acgcactctt caggtactct gccagcggct tgtgatagcc
    19021 tgcgtcgttg gtcatgtact cgatcatcgg gaagccttcg ccgttcggat agcccgcgtc
    19081 tgctaaaagc tccttggcct tggccagatc gccctcgaaa tcgtctgtat ggaagaactc
    19141 gccgtaggtc tcgatggtca cgtcggagaa ggaggatccc ggctctacgt cggaaactcc
    19201 aggtcccaca aagttcttgg ccggagtgta ggttccctgc atgatagtat ccgctatgta
    19261 ctggcgatcc agcgcaaggc ttaacgcctg gcggactctc acatcctgga aatacccgcg
    19321 gttcagattc aggctgatgt agtaggttcc cagaagcggc tccacgcgga actcaggatt
    19381 ctctctgagt tttggaatct cctctgtggg aacgtccttg ataaacataa cctcgcctgc
    19441 gttgtatgcg ctgtaggctg cgtttgcatc ctccatcagg acaaatttaa tggtatctgc
    19501 cgtcacggcg tctgcattcc agtaattctc attcttttcc atgagaatgt gggagcctgg
    19561 cacccattcc ttaatcttca tggctccgtt gcagatatag gttgccggat cgatggccca
    19621 tgcctccccg ttggcctcca cagtcgcctg ctgaaccggg ctcagcgtag tataggcgca
    19681 gatcttgtca aagtatacgc acggatgggc cagctctact acaaaggtct gatcgtctgg
    19741 agcggatact gccaatgcgt ccagatttcc ggcagccgcc tcgtcgtagc ccttaatcat
    19801 gcacagaaga tcatagccat agggagccgc tgtcatagga tccgacacgc tcttaaaggt
    19861 atagacaaaa tcattggctg tgagcggcgt tccatcgctc cacttcaggc cctcgtgcag
    19921 atggaaggtg taggtcagac catcctcgga aacgtcccag gtctccgcca ttccgccgat
    19981 gatattgttg tccttgtcca tgttcagcag aggctcaaac agatggataa tcatgatgtt
    20041 tccatcgctg gcgctgttta acgccggatc aatggtctcc gggtccgggc ctacctccac
    20101 gaccagatga ttcccctctt ctcctgcctg ggcctcctgg ccctctcctc cgtctggctt
    20161 ggaatcgttt cctccgcatc ctgacagtac ggctgatgac agcatcgctg ccgccagcac
    20221 aagcgcaagt ttctttttca tcctattcct ccttcatatc tctggggatg aggcctgtgc
    20281 cgcctggaga aatctcttct gcccaaagaa aaaaacctcc cggacgccgt atcggcgcct
    20341 ggaaggtttt tcctgcctgt gtctgattat tatattattc tgccgcctct gcagaagtct
    20401 ccgcctctgc aggcgctgct tcctccgcct gtcctgcgtc gccataggaa gcatacataa
    20461 aataccagta gccatatgga gaatgccagg ttccctgaag ctccggcttc tgaagccaga
    20521 aatcattgtt ataggcaatc ggaatcatgc ccatatcgtt taacagaagc tgctctgctt
    20581 cgtgaagaag ggagtagtgt tctgccttgt ctactgtctc tctggcgctg gcaatcaggg
    20641 catcgtactc tggattgtta tatcgtccat cattgtttcc gtttgtagac tcaaaaagat
    20701 tcagcatgtt ggatggatca tcgtagtcat atacccagcc gtttcttgcg atatcatagt
    20761 cgccgtttct tctggttgga gtgaatgatg cccactcaat aatcttaatg tctgtattga
    20821 tacccagctc gccccatgcg ctctggagat actctgccag ggccttgttg tagcctgcgt
    20881 cgtttgtcat gtactcgatc atcgggaagc cctcgccgtt cggatagccc gcgtctgcca
    20941 gaagctcctt ggccttagcc agatcgctct caaaatcgtc aacgtggaag aactcgccgt
    21001 actctgcaat ggtggtctcc tggaaggaaa ctcctgcctc cgcgtcggaa acgcctggtc
    21061 cgataaagtt cgtagccgga gtgtaggttc cctgcatgat agtatctgca atatactggc
    21121 gatccagggc aaggcttaat gcctggcgaa ccttcggatc ctggaagtat tctctctcca
    21181 gattcaggct cacatagtag gttcccagaa tcggagctac atggaattcc ggatcttctc
    21241 tcaggtttgg aatttcctct gtgggcacat ccctgctgaa cataacctca cctgtcttat
    21301 acgcgctgta ggctgcgttc atatcctcca tcaggacaaa cttgatggtg tctgctgtga
    21361 ctgcctcagc gttccagtaa ttctcatttt tctccatgag aatgtgggag cctggaaccc
    21421 actctttaat cttcatggga ccattgcaca cataagtagc aggatcaatg gcccaggact
    21481 cgccgttggc ctccacagtc gcctggttga ccgggcttaa cgctgcgaac gcgcagatct
    21541 tgtcaaagta tacacatggg taggaaagct ccaccacaaa ggtctgtgca tctggagcgg
    21601 aaactgccag ggcgtccacg tttccgttct cagcctcgtc gtaacccttt accatgcaga
    21661 gcaggtcgtg gccgtaagga gccgctgtca tcggatctgc cattctcttg aaggtgtata
    21721 caaagtcctc ggctgtaaag tcagagccgt cgctccattt taatccctct ctcaggtgga
    21781 aggtataggt gagaccgtcc tcggaaacct cccaggtctc tgccattccg ccgattacat
    21841 tgttgtccct gtccatagtt aagagaggct caaataaatg gataatcatg tttgacgcat
    21901 caatagcact gtttaacgcc ggatccatag tctcaggatc tggtccaagc tgaactacca
    21961 ggtgatttcc ttcctctgcc acaacgcctg cgtctcctgc gcctgcgcta ctgtccttgc
    22021 ttcctccgca gccggacagc acagttgtgg aaaccatggc cgctgccagg agaagtgcga
    22081 acttcttttt cataatgtct tcctcctcag gtcgtaaaaa aatattataa catgaattca
    22141 cctccctgcc ggacggcagg gaggcaaact gttaagcttt ttagttgatt ttatctaagt
    22201 ggtggcaggc tgcgtaatgg cccttggaaa cctcacgcca ctccggcgcc ttctcagcac
    22261 agagctcagt ggcgtagggg catctggtcc tgaaggtaca gccgctgggc ggattcaccg
    22321 ggcttggcac gtctccgctt aacacaatac gcttagactc cctgcttgtc tttggatctg
    22381 caatcggaat cgcagaaatc aggctcttgg tataagggtg aacgctgtgg aaggtcagct
    22441 catagctgtc agctaactct accagcttac ccagatacat aacgccgata cggttggaaa
    22501 tatgctttac aatggacaga tcgtgggcaa taaacagata agttaagccc atttcctgct
    22561 gaagctcctc aaacatattt actacctgtg cctgaatgga cacgtcaagg gcagataccg
    22621 gctcatcgca gacaatgaac tccggatcta cagccagagc gcgggcaatg ccgacacgct
    22681 gtctctgtcc gccggagaac tcgtgaggat agcggttggc atgctcagag ttcaagccta
    22741 ccctctccag catacggatg attctctcct ggcgctcctt cttattggaa gccagcttgt
    22801 gaatgtcgat ggcctcgcct acaatgtcgg caaccgtcat acggggatcc aggctggcat
    22861 aaggatcctg gaatacaatc tgcatctttc tgcggtaggg aagcatgttg accttcgtct
    22921 tatggccgaa ctgaacctcg cccttctcgt ttaagacagg ctgtccgttc tcatcagtca
    22981 gcggcacatc tccgctgtca aaaatagtgg ttccatcata agcaatgcgg ccgctggtcg
    23041 gctcataaag gcgcagcagg gtacgtcctg tggtggtctt tccgcagccg gactctccta
    23101 ccagtcccaa agtctctccc ttattaataa agaaggaaac gtcgtctacc gcctttacca
    23161 cctttttctc gaaaagcttt ccgctggcaa cagggaaatg ctgttttaaa tgctcgattt
    23221 caagcagctt cttattctcc attacttgtc acctccctgt gcctttaaaa actcctcctt
    23281 ctgcagcagc cagcaggcgc tgtagtggat gtcggacaga tctgtatact ccggcatctg
    23341 ctttaagcag attttcatac aggactcaca ccggggcgca aacggacatc cggcaggcgg
    23401 gttcagcata tcgaccggtg agccttcgat cggaacaagt ctcgtcttct ccttctcgtc
    23461 cagacgggga atgctgcgca gaagtccctt ggtgtattcg tgggacggac gatagaaaat
    23521 atcgtctgtg gttccgtact caatgacctt tccggcgtac ataacggcaa ttttgtcaca
    23581 catgctggct accacgccca ggtcgtgggt gatcatgata atcgccattc ccagcttctg
    23641 cttcagctcc atcatcagct ccagaatctg agcctggatg gttacgtcga gggccgtcgt
    23701 cggctcgtcg gcaatcagaa gcttcggctc gcaggccagg gcgatggcaa tcataacacg
    23761 ctggcgcata ccgccggaca gctcgtgggg atactgcttt aagcgcttct ccggctcgtt
    23821 gattccaacg agagtcagaa gctccttcgc tctctccctt gcttcctgct tagttttctt
    23881 ggtgtggagc aggatcatct cgcagatctg atttccaatg gtgtaaaccg ggtttaagct
    23941 ggtcatcgga tcctggaaga tcagggagat ttcctctcct ctgatctttc tcatctgagc
    24001 ctcgttcatc tgatcgatct ggtggccgtt aaactcaatg cttcctccaa tcaggcgtcc
    24061 cggataggcg gtcaggccca tcaggctgta agctgtaaca gattttccgg agccggactc
    24121 tcctacgatg cctaacacct ctccctcctt taaatgaagg gacacgtcgt ttaacgcctt
    24181 aacctctccg gccggcgtaa agaaggaaag gcgctcgttt ttaatattta caagatattc
    24241 actcatgctt gtttcctcct tagttcttca gcttcggatc gaaggcgtcg cgcagtccgt
    24301 ctcctaacag gttaaagctc agaatgataa tggaaatcat cagagccggg gcaaacagac
    24361 gatacggata gctctgcaga ccgtttaagg ccgcgctggc aaggctgccc agagacggca
    24421 tgggggcgtt tactcccagt cccaggaagc ttaagaagct ctccgtgaag atggatgacg
    24481 gaatctgaag cgtggtcgta acaatcagag ttccgatgca gttggtcagc aggtgcttct
    24541 tgatgatgct gccgctggaa gcgcccaggg ctctcgccgc tgttacgtac tcctgctcct
    24601 ttaaaatcat aatctggctt cgcacgatac gggccatacc aacccagtac agcagggcga
    24661 ataccacgaa aatactgatt aagtttacgc cgatgaggcc gatccactca aagcccggct
    24721 tcatggccag ctcctttaac ggatagttta acactgccgc cagaaggatt acgataagaa
    24781 catcggggac ggtgtatatg atatctacaa tacgcatcat caccatgtcc acccagcctc
    24841 cgaagaaacc ggcgatggat ccgtagaggg atccgattaa taaaatgata gcagaggcta
    24901 ccagtccgac ggtcagagat acacggcttc ccatcataac acggatagcg tagtctcgtc
    24961 ccagctgatc cgttcccaga atatgcggga acaccttctc cccgtttgca atagcctcct
    25021 gctctgcctg ggaatactca aagggcgcaa ggctgttgct tcccttgatc tgctgctcat
    25081 atttataagg ataaaactgc ggtacaataa atgagagaat gaaaatgaga attaccacaa
    25141 taaggcttac catggcaatc ttgttcttct taaaacggcg catgccgtcc ttccagaagc
    25201 ctacgctctc tctcatcacc acaagacttt tcttctcgtc ctctcctgcc gggaggaagt
    25261 cgtctgcatt taactgaaat gacagtttat tcttctccat aattgcctcc tccctacttc
    25321 agtttaatac gcgggtcaat cagggtatac gcaatatcca cgatcacgtt cataacgata
    25381 atcagtactg ccaggaaaat ggtagtaccc atgatcagcg gataatcacg gcctgtgatc
    25441 gctccgataa actcagaacc aagaccagga attgtaaaga tcttctctac aataaagctt
    25501 cctgttaccg tataggctaa cagcggtccc aagtaggtga caaccgggag aattgcgttt
    25561 ctcagcgcat gcttgaacac gcttaccatc catgaaacgc ccttggctct cgctgttctc
    25621 atatagtcct gtcccagcac gtccagcatg gaggaacgca tcaggcgggc aatataggag
    25681 gacgggtaaa gggccaggga gataaccggc atgatgtagt gcttccagga ggtgagtccg
    25741 taggttggaa gcagtcccag ccagttgctt aaaatctgca tcagaagggt acagattacg
    25801 aaactgggta tggcgattcc gcaggtagta aacaggataa taatattatc aaccatcttt
    25861 cctctgttga aggctgcaac gcttcccaaa ggaacgccga tacagacagc taacagaatg
    25921 gctactcctc cgatcttggc agatacaggg aactttgtct caataattgt gttgactgta
    25981 cgtcccctct gctttacact ggggcctaaa tctccatgga gcaaatcctt catatagatt
    26041 acatactgct ctggaagagg tttatccagt ccgtactttt ccatcattgc ttcctgagcc
    26101 tgaggcgtca gagctttctc agccatgaac gggcctcccg gaaccaaatt catcaggaag
    26161 aatgtaagag tagcaaccag ccaggctgta accactgcca ggccaatacg ctttaaaatg
    26221 tattttgcca tcgcttatct cctttcccgc attgccccgc taaagctgca gaataaaaaa
    26281 acagaacgct ttattctgag caaaaacata tgtaggctat gtgcggacat ctctgcgtaa
    26341 agaaaagggc tgccgcaaaa taggaaccct gcggcagccc cttttcgttt ggaattacat
    26401 tcccatctgt tttgctactt cgtcagcaaa gttctcttcc ttcttctcaa ggccctcgcc
    26461 tgtctcgaag cggacaaact tcttaatagc taccttagca ttgttagcct tggcaacctg
    26521 tgcaacatac tgggaaacgg actgctttcc atcctctgcc tttacgtata cctgatctaa
    26581 taagcagatt tcttttaact ctttgttgat acgtcccata accataccgc tgatgatctt
    26641 gtcattagcg tccggcttct cgttcttagc agctactgtt aagatctctt tctctttctc
    26701 gatgtagtct gcgtcaacct cgtctctgtt tgtgtataat ggctttaatg ctgcagcctg
    26761 catagctacg ttcttagcca tctctctgat ctcgtcgttt acaacgtctg tctcaacgtc
    26821 tactaaaacg ccgatctttc cgcctgcgtg gatgtaagaa gcgacaaatc cgtttgcagc
    26881 agtcatcttc tcatatcttc tgatcttcat gttctcgccg atgatggaaa tctgggaaga
    26941 gagagcctct gcaactgtga gtgtctcgtc ctttgcccac ttctctgcca tgaaagcgtc
    27001 catatctgca gcgtcggaag caagagcctg ctctgctacg tctgctacgt agttctggaa
    27061 cttttcattc ttagcaacga agtctgtctc agcgtttacc tcaacgacaa ctgctgtctt
    27121 ctcgtcagct gccatctttg tcataacgat accctcagct gcgatacgtc ctgccttctt
    27181 agcagcgccg gcaagtcctt tctctcttaa gaactccact gccttgtcca tgtcgccgtc
    27241 tgtagctgca agggccttct tgcagtccat cattccagcg cctgtcatct cacgtaattc
    27301 ctttaccatt gcggctgtaa ctgccatctt accatacctc catgtttttc taatttaacg
    27361 cagggtgcgt atcctgcgga aaagtccgcg gagccggaag ccggtcccgg ccttctgctt
    27421 cgcggatttt catttatctt gctcttaaat taagcctctg ctgtctcctc agcgtcctct
    27481 ccctcaacag gagcctctgc ctcgccctgg ttagcctcga taacagcgtc tgccattctg
    27541 gacacgataa gcttaacagc tctgatagcg tcgtcgtttc ctggaatcac gtagtcaagc
    27601 tcttccggat cacagtttgt atcaacaatg ccgattaacg gaataccaag tgtgtgagcc
    27661 tcctgtacgc agattctctc cttcttcgga tctactacga agatagcgtc tgggattctc
    27721 ttcatctcct tgataccgcc aaggttcttc tcaagcttct cccactcctt cttaagagcg
    27781 ataacttcct tcttcggaag aacatcaaat gttccgtcct ctgccatggt ctcgatctct
    27841 tttaagcggt tgatacggct ctggattgtc ttgaagtttg tcagcattcc gcctaaccat
    27901 ctctcgttta cgtagaacat tccgcatctc tcagcctcaa ccttgatagc ctcctgagcc
    27961 tgcttctttg tacctacgaa gaggattgtg ccgccctctg cagcgatgtc ggatactgcc
    28021 ttgtaagcct cgtctacctt gcctacggac ttctgtaaat cgatgatgtg gattccgttt
    28081 ctctctgtgt agatgtacgg agccatctta gggttccatc ttcttgtctg atggccaaag
    28141 tgtacgccag cctcaagtaa ctgcttcatt gaaataacgc tcatgtttct ttcctccatt
    28201 tggtttttct tccgccggca tctttcgctc cccctgggac ctgtttccag gcaccgtcct
    28261 ggagaatccg ccgtgcgtga tttttcaact tttatactat atcacagggt tttcttttat
    28321 gcaagcactt tattgcgcca tatatttctc tgcaatctcc ttaagcgtct ccctgtgctc
    28381 cgggaaccac tctgcaaagg tctgtcccgc cttttccacg gtctctccca cctctgccat
    28441 aaaggccgga atgttctctt ccagcatggc gccccagtcc tctccgaaac gctcctctcc
    28501 ctggagctcg tttccgttta catgaaggtt aaaggcaggc ttcggaacct tgtcaatcac
    28561 cttgacgcct ccgcggaatc ctaacgttcc cgcctgatgg gttccgcagg aggacggaca
    28621 gccggaaatg tgaatcttag gaagagttcc gtccttaaag ctgtgctttc tcacttcctc
    28681 cacaatggat ttcatcagat tctgggaatc tctgactccc acctggcaga tgaacgaacc
    28741 gatgcaggcc acggaggttt caaacaggtt ctctgcgctg tcctttaata cgtccagcac
    28801 ctgcagagcc tctctggccg tcaggttaat cacatacata gcttcctctg gatccaggcg
    28861 catctccacc tgctccatat ccttcactgt ctcataaagc attttaaata atgatggatc
    28921 cgggcttcct gcaatggggt ggaactctac ggcaaagagt ccctcctgct tctgtgctgt
    28981 cacccggcgg cagtgaaggg cagctttttc ttcctctgtc agctgtccca gaatctctga
    29041 tgccagcttt tccttctctt ccaggtgaag ggcaaacagc tcttcttttt taagcttcag
    29101 cccatccttt tcctggtcca tcacttcttt aagcttctcc tggtatgcct taacatattc
    29161 ctcttttccc agcttatcct gcatatagcg tgttctggcc ttagcccggt tctcataatc
    29221 tccataggct gtaaacgtat ttaccatagc cttaatatag tagagaatat cctccggttc
    29281 cactgcttct gccaccagaa ctcccatctt gggattcgct cccagtccgc ctgcgctgta
    29341 cacatcaaac agtccgtcct ctctggccgc aaagcccaga tcgcggaagg tggcgtgagg
    29401 acggttagcc ggcgaattgg aaaagcatac cttcaatttt ctcggaagct tcaccgtctt
    29461 gataaagccc atcagatact ccgctgcctt gagagcatag ggaagcacgt cgaaccactc
    29521 tccctgctcc acgccggaaa gaggggacac catgacgttt ctcggaaaat ctccgcctcc
    29581 gcctctcgtg ttaatgccca cgtccagagc ttcctccata atttcgcaga cagacgttcc
    29641 attcagattg tgaagctgaa ccgtctgaca ggtagtaaag tgaacctgat tgatctgatg
    29701 cttctcaatg ctgtctccga taaatttcag ctgttccttg gtcatacgtc ctccggacag
    29761 gcggagcctg agcatactgg cctcagcgcc tctctgggcg tagcttccaa agcctccgga
    29821 aaatcccttg taatccttcg ccgacacttc cttattataa aacttctctg tcactgcctt
    29881 aaattctgct aaatcctgct tccacgcttc atttcccatt ccttgactct ccttttccca
    29941 ctccgcctat gtccgctctg tctccggccg ttctgtatcc ggccgcaagt ctgctgctgc
    30001 ggacgccgct tttttctttt tatagtagcg gattccaaaa ataaagtaaa attatatttc
    30061 tttatctttc cataataatt tattattgat atactggtat cagcatatag tttgcgtaag
    30121 gaggtattta tgctggataa ccgcatctac acatttctgg cagtgtgcca ggagatgaat
    30181 tttacccggg cggccaaaaa gctgcatatc acacagcctg ctgtctccca gcacattcag
    30241 tatattgaac ggtattacgg cgttcatgcg tttcgcttcg agggaaaaaa gctttctctc
    30301 actccggagg gagagcttct ccgctctgct cttctgacta tgaaaaataa cgaggagagc
    30361 ctgaaaacgt ccctctccaa atctgccggc cagatttctc ctctccgcct gggggctact
    30421 ctgacagcgg gaagctttct tctggccgaa cctctcgcca ggctgttccg caggtggccg
    30481 gatcttcctc tttcagtgac tgtcaagaat acggctgacc tgctggcgca gatcgacgac
    30541 ggctctctgg atttcgccct gctggaggga aatttctcca aggcctccta ctcctatctg
    30601 gtctacctga gagaaccgtt cattcctgtc tgcggcccgg atctcctttt tcagatgaaa
    30661 tgtatgcaaa aagaaaaggg cctccctctc tccctggagc agctgacagg acagcggctt
    30721 ctgctgcggg aatctggctc gggaaccagg atgattctgg agcagattct ggaagagcgg
    30781 gggctctttg tatctgattt taaaaacaaa gcggaaattg agaacatgca ggccatcaag
    30841 gatctggtag ccgccggctg cggtatcacc ttcctctaca aaagcgcagt ccagagagag
    30901 ctctgcgatg gaaccatctg tgaaattccc attgaaaatc tgtggctgga acacgaaatc
    30961 tctgtagtct ggcaaaaaaa ccggctcttc cagaatcaag tcacgcaggc tgtcaaagaa
    31021 gcctttggcc ctggctttgg ggaggaactg gcctaaaagg tctttcctcc gcaaagctcc
    31081 agcgccacca aatctccatt ctggtattcg cgttcaaact ccctcaccag aagctctccg
    31141 ccctctgttt tcacaaaata ctgggtataa aagcccatgt aatccgattt cactatggtt
    31201 cctgtgagca gatgtctgcc gtccggattc tgcgcctgtc tctctgtccc tttatccttt
    31261 cgcgcttttg tctcctccgc cttccccaga attctgatat cctctggtct gaaataaata
    31321 agacttccgt ccggcatggc tgcccgatcc gccgttccca aaaattccat gacaaacagg
    31381 ctggccggat tctggtacac ctctctgggc gctcccatct gaatcagcct tcccccctcc
    31441 ataatggcga ttttatctgc cagggccata gcctcctcct ggtcgtgggt gacaaatatc
    31501 atggtaattc ccgttttttt ctgcagctcc ttcagctcgt ccctcatgcg gatccgaagc
    31561 ttggcatcca gattgctcaa aggctcatct aacagaagca ccttgggatt cactgccata
    31621 gagcgggcca gagccactct ctgctgctgc ccgccggaaa gttcctggac agaagacgac
    31681 gcccggtctg ccagccccac aatctctaaa tattcccagg cccgctcagc cgcctccttc
    31741 tttttcattc cctgaaattt caggccgtac atgacgttct ggagagccgt catatgggga
    31801 aacagggcgt aggactgaaa tacggtggat acgggacgtc tctcaggagg aagctttgta
    31861 atatcctccc cgtccagata aatatggccc cgatccggtt caagaaatcc ccctgccatc
    31921 cggagcgtcg tggtttttcc gcagcctgac gcgcccagca ggcagagaat ctctccctga
    31981 ttcatagaaa gattcaggcc agacactacc tccttcccgt caaaggattt actcaaatct
    32041 ttcatttcca gatacatgcc gcgcctcctc tttttttctt ttcttcggct tttcccgaag
    32101 gacgagagcc gatactccgc ctgtcacagc gatggtaatt acaataatca tggacgaaat
    32161 cagggacgcc actccgtact ctcccgaatt gatcgcgtca aacagcgtgt acactgccag
    32221 cttgtgtctg gcgctgatta agaacatcac ggctcccgcc gtggtcatgg cgctggagaa
    32281 gttgtaaata aatcctgtca caaaggtgcg ctttaaattc ggcatcacaa tatctttcgt
    32341 cacaaaaaag cgtcccgctc ccaggtccct ggccgcgtcc tccacccggc tgtttagctg
    32401 agccagggaa gcgcttgtca gcttcatgac catgggaagc tgtttaaata tcatgttaaa
    32461 aatgatgatg gccgccgttc ccgtcatttt cagcggttcc ctgttaaaaa caagaatata
    32521 tccgattcca aagcaggtgc ctggaagaag gtacggcatg gtggcgataa aatcgtaaaa
    32581 gcccctgaat ctcacctttc tccgttccag atagtaggcg aacagcatgg cgaacagagt
    32641 tcccgccgcc gccgtgatca gggaatacag gacgcttctg gccaggctct ctatattgta
    32701 ggtcagaagg ccgttaaagt gatccagcga gaaataatag cgtccctttt tggactttaa
    32761 aaaccccgtc aggaaaatgc agagatactg cagcgtcatc atcacgaaaa acagggagga
    32821 cagcagtctg acggctgctc cgaaccaccc ggcgagggga aggggcaggc cgccttttcc
    32881 ctgtttctgt ccatccgccg ctgtcatccg atctgcctgc cgcatcagaa cgcggtacag
    32941 cagaaaggcc gctaccgccg gaaggagcag cagcatattc atggcagagg ctttttccag
    33001 atccgcgtag ccgattaact ccatgtaaat ggcagaagcc agggtattat atcttcctcc
    33061 gattacagct ggagtcccga aatcagccac cgagcggata aaggacagga taaagcagat
    33121 ccccgccgca ggcttcagca tgggaagcac cacccgcctc atggtctggg ccggagaggc
    33181 ccccaaatct ctggacgcct ccagaaggcg caggtccagc ttttccagaa ttcccactgc
    33241 aaacagggcg tttaaagaag cgaaatgaac tgtctgcatg ataataatgc cccacttatt
    33301 gtaagggctt aacatcagtc caagcagacg gtaagtaatc catcccctct ttccaaacag
    33361 ctggatgtag accagagagg aaataaacgg cggggaaacc atcgtcatca gaaggatccc
    33421 catgaaaatc cccttcatcc cccccttcat tgtcacaatg aagagggcca ccgcaattcc
    33481 cagaatcgta gaaaaaacag ctgccagcac gcctgtaaaa gcgctgtggc ggatgagaac
    33541 gccgttttcc cggaataaat tttcataggc agccaggctt acgccctccc ccagattcac
    33601 gcttttagcg gcaattccaa ggagaggcca caggacgaaa agaagaacag ccgccgccat
    33661 ggcgcagaat aacagcctgt ccccgcaaag tcccaggaag gcctttctgt cttttgcgca
    33721 ggaaaaaagg gcatccaagc cagataccct ctttcctcta ttctgtctgt tcttcgtcgt
    33781 cagcctactc attttcagac ttatcgcctg ccagctcgtc ccacttggca aggatagcct
    33841 ctctctgaga gccgaataag gataaatcct catccatcag agattctacg tcaaaggtaa
    33901 gctccagccc ctcgatgtcc ggcttcacca tcttaattgt gtctttattg tcaatgtcag
    33961 ctgccatctt caggttctcg tcgtcagaat agaaccactc gatgaattcc ttggcttcct
    34021 ctgccccctc agaattctta aatacagcga ctccctccgg aacgtaagga attccgtcct
    34081 ctggataaac ggcagtcatg ttctgctcct cctgaagctt gtccacttca cgatccatag
    34141 gagcgattcc aatggcaaac tcgcctgcca tggtctttgt cagcggatcc tttcctctct
    34201 tggaatagta ctcgatattt ttattcagtt cctcgaaata gttccagccc tcttcttctc
    34261 ccttagcctg gagaattgcg tttaccaccg catagttagt tccggaaata gccgggttgg
    34321 acatgatgat ctcgccctgg taggctgtat ttgtcagatc ggcccaggac tttggaatct
    34381 ccagtccttt ctcctcaata atatcgttat ttaccacaaa gcctactact gtaagacctt
    34441 ttgcaaacca gtagttgtca gcgtccttgt actctggagc caggttagcc gcctcgtcaa
    34501 agttcacctg ctccagcagg ccgtcctcct ttgcccccat aaacgcgtcg attccgcctc
    34561 cgaaccagag atctgccata ggcgttccgc cctcagcctt aatcttggaa agcacctctc
    34621 cggaagacat ggataaaagc tctgtcttaa ttcctgtctc ctctgtaaac ttgtcaaaca
    34681 gctttacata atcctcgctg gttgccacta cctttaaggt tccgtccgcc tttttctcct
    34741 cagcttcagc ctctgtctct tcagccgctg cagaggactc ctgggctgct ccgctctctg
    34801 cagacgcagc tgtagtctcc tgtccgccct gagagctgca tccggccagc ataagagctg
    34861 ccaggcctgc tgtcataatt cctgccagac ttttcttttt catgttccat ttcctcctga
    34921 tacaatcgcg tcagcgcccg ctgcgccgtg ctgtactgcg aaaagcattc tgctttttat
    34981 ttcaattatt tatactaccc ctctcctgtt tctccgtcaa cgctttcccc tgtttttata
    35041 cccatttata gaattttcta taagtggggc gatttattga ttttttctat caacaggccc
    35101 ctctttcttc cttgactctc tttctcctgt gctgatacaa ttttttacag aatcccgcag
    35161 tagatccggt gtctcatccg ccggcagaca gcctgggaaa ccggacgaaa cgcagagcgg
    35221 gcacagggag gttacggaat gtttgtagat cttcatatgc atgaacggac attttcaaaa
    35281 gacagctttt taacgctgaa ggaaattgtg gagattgcca aagagaaggg gttagacggc
    35341 gtctgcatta cggatcatga cgatattgga atcaaggaat acgcggaaca gtattcaagg
    35401 gagactggat ttcccatttt tgtgggatat gaattttact ctctccaggg cgacatcctg
    35461 gctttcggag cgcccaaagt cccctctgag cgcatctcag cccaggaatt tgtagactat
    35521 gtaaaaagct tcggaggcgt gtgcattgcc gctcatccgt ttcgaaacaa taacagggga
    35581 ctggaggaaa atctggccac tgtcaaaggc ttagacggga ttgaggctct gaacggaagc
    35641 acccttccgg atgcctgcag caaggcattt tcctacgcaa agcggctggg aatccagtgc
    35701 accggagcca gcgactgcca cgtgccgtcc aaagtaggcg tctacgccac ctggcttccg
    35761 gaaaccgtct ctactctgga cgactttatc tccgtgttca agaagggcca gtgccgcccc
    35821 gccgtgtaca agaacggcgg atatgtggtg gtcgagcagg cgcagtaaga aaaataggaa
    35881 aaacagaaaa ctttcaaccg tctgactaaa aaaacgggaa gagcagaaag gttccccact
    35941 ccagccggaa gccgctggaa cctttctgct cttcccgttt attcttactt atttcttcat
    36001 ctcttcaatc gattcagact tcagaggaat gtttacatca ttcccattcc gcctgctccg
    36061 ccaggaacag ccggtgtctc ctctttgatg tttgcaacta cagactctgt agtaagcagt
    36121 gtggaagcca cgcttgtagc gttctgaaga gcgcttcttg taaccttggc cggatccagg
    36181 atgcctgcct ctaccatgtc tacatacttc tcattgtatg cgtcaaagcc cattcctacc
    36241 tcagactctc ttaccttgtt gatgataacg gagccttcca ggcctgcgtt ggcagcgatg
    36301 tggaacagcg gagcctcaag ggcctttaag ataatgcggc cgcctgtctt ctcgtcgccg
    36361 tccatagcct caacaacctt ctccacttcc tttgtagcgt ggatataagc ggaaccgcct
    36421 cctgcgatga tgccttcctc gacagctgcc ttagctgcgg ataacgcatc ctccatacgg
    36481 agctttgctt ccttcatctc tgtctctgta gcagcgccta cgcggataac tgcaacgccg
    36541 ccggacagct tagccagtct ctcctgtaat ttctctttat caaattcaga ggtagtctcc
    36601 tcaatctgag ccttaatctg agcgattctt gcagagatct catccttgtt tccgcagccg
    36661 tccacaatga ttgtgttctc cttctgaacc ttaacggatt ttgcacgtcc cagcatatcc
    36721 atagttgtct cttttaagtc gagcccaagc tcttcagaga taacctggcc gcctgtcagg
    36781 atagcgatat cctttaacat ctcttttctt ctgtcgccgt atccaggagc cttaacgccc
    36841 actacgctga aggttcctct taacttgttg acaatcagtg ttgtaagagc ctcgccctcg
    36901 atatcctcgg caatgattaa cagcttagcg cctgcctgaa ctacctgctc taacagcgga
    36961 aggatttcct ggatattgga gatcttctta tctgtaatta agatgtacgg atcgtccaga
    37021 tttgcttcca tcttatccat gtctgtcgcc atgtaagcag aaacatagcc gcggtcaaac
    37081 tgcatacctt ctaccaggtc aagctctgtc ttcatggtct tggactcttc gatggtgata
    37141 acgccgtcct tggaaacctt ctccatagcg tctgctacca tctggcctac ctcgtcgtca
    37201 gcagaggaaa tagctgctac tcttgcaata tcagccttgc cctttactgt cttggacatg
    37261 ttctggatag cctctacagc tgcctctgtg gccttcttca taccttttct taaaacgatt
    37321 gggttagcgc ctgctgccag gttcttcatg ccctcgttga tcatagcctg agctaatacg
    37381 gtcgctgtcg ttgtgccgtc tcccgctacg tcatttgtct tagtagccac ttcctttaca
    37441 agctgtgcgc ccatgttctc aaaggcgtcc tttaactcga tttcctttgc aatggtcaca
    37501 ccatcgtttg taatcagcgg agcgccgaaa gatttgtcaa gaactacgtt tcttcccttc
    37561 ggtcccagtg taacccgtac tgtatctgct aactgattta cgcctgattc cagcgctttt
    37621 ctggcctcta cgccgtactt aatttccttt gccatggtga tcaacctccg atttatttga
    37681 atttactttc tgctgttttc tgatgcgcgt cctgaccgtt tggcttactc aatcacagcc
    37741 agaatgtcgt tctgctttac tacaacgtat ttctcgtcct ctacctcaac ctctgttccg
    37801 gagtatttag agtagataac cttgtcgcca accttaacct gcatggaaac ttccttgccg
    37861 tcaactacac cgcctggtcc tactgcgata acctcagcct gctgcggttt ctccttcgcc
    37921 tgtcccggaa gcacaatacc ggattttgta gtctcctctg caattaactg ttttaaaaca
    37981 actctgtcaa ataatggcac taatttcatt actgactcct ccttactgtt tgtagttttt
    38041 ctaaaatctg acagcggaac agttcggctt tcttccgact gtctcctgtt attgtctgtt
    38101 tcctgtaaat ctttaccttt ctcacttaca acacaagtta tatcacgctt tactagcact
    38161 gtcaagagtc gagtgctaat ttttaggaaa tttatatatt ttttattttg ccgtttccaa
    38221 tctcagcaaa accaccctgt ttttttctat tattatctga tttttcccat aaaatccatg
    38281 tttttcctcc tcttactaca gtttcctctt tagtttattc tatttttcac aatttattca
    38341 taccgaatcc ctttattttt cctccaaatc gtattacaat aaagggaagt acgaagctcc
    38401 cttttgaagc ttcgtacttc ccgctactca aacggaacgc agtgaagttt gagattcctt
    38461 actcccgctg ctcaaacgaa gcacagtgga gtttgaggtt ccttactccc gctactcaaa
    38521 cgaagcacag cggagtttga ggttcctgat acatcagcgg aacagttcaa aaatacaata
    38581 aactaaaaat gatattaaaa ggagtatact atggcaaaaa aacagtttgg aaaactcgca
    38641 gtcctggccg ctctggcggg aactgccgtt ggaattacct attttctcag atacaaatcc
    38701 ttccacgaag agctggagga ggatttccat gattttgaag aggatttaga cgaatttgac
    38761 agcaaggagg aggaagcctc tgcgaagcgc aactatgttt ccctgactcc ggaaaaggca
    38821 gattccgctc aaaaagagac tgtgcctgct tctgcaaaag aacatccagc agcagaacaa
    38881 agccctgagg cagagaagaa agctgatgag acgcagaacg actttttaga cagcgatatg
    38941 gagttcctgg acgacgagcc aatggacggc gagtctatgt ttgatgaaga ggatattcca
    39001 gacactgctt catcttccgc taccaccatt gtggaagatg aagaaccgga acaataatgg
    39061 aaggcggttg actctatgat tcaaagcctc atgcgctccc tggatctcct ggaggtttta
    39121 aaaggagcag atcacaaaat atccatcgca gagctgtctg agcagctgga gcttccgccc
    39181 agcacgatcc accgaatcct ccataccttc tgcgagaaga aatatgtcat aagagacgag
    39241 tacacccaca cctactgtct ggggcctgcc ctgatctctc tgggccgcgc tgcagcttca
    39301 aatgtccgga tccaggatgc ggcacttccc atcctgaaaa atctctctta tgtaaccaga
    39361 gaagattcct atctggtgat ccaggtgggt gacaaaggcc ttgtccttga taaggtagac
    39421 ggccccaatc acctaaaggt ggtagaagaa ttcgggtacg agctggatct gcactgcgga
    39481 gccatccgca aggtcattct ggcctaccag agcccggaat acctggacta ctacaccaga
    39541 caggtcttag accgtccgga ggcgtttccg cagaccagcc ggagcggcct tctggcagag
    39601 cttcgcgaaa tccgtgagac cggcctgtcc gtctcccacg gcgaatacgt ccacgacgcc
    39661 atcgggatcg gagctcctgt ctttggcatt aacggcagcg tcactgcctc tgtgggcatt
    39721 attgcgccct acagccggat tgccgacaag gtgcatctgg agcacatgaa ggagcaggtc
    39781 cgccacagcg cggcggagct gtcctactac atgggccaca cgtttaagca ggtctgatat
    39841 ctgcctgaac ttccaaacac taaaagcaac gaaaaagccc cgccggtggg tgtgaaaacc
    39901 tctgccggcg gggaactttt tttgttcttt tattccgttc ttttatttca gctgtttcag
    39961 cggaaagact ctgctgcgtc cagcgtatct ctcccccaaa accggccgga aaggaacctc
    40021 gtcaggctcc ctctggccgt ttttgctgtt ttttactttc tcatctcaag cacatctgcg
    40081 aaggcctgaa ttgctgtacg agcctgtccg aaatcgcgca tctgctgatc gatacccagc
    40141 ttgatatgcg gaacgtctgc tgcctgtaat gctttcttca ggtatggata ctccatctcc
    40201 tccggatcgc agaactgctg catgaacaga accagtccct gtgctccgct ctccttaacc
    40261 aggttggcaa cgaactcgcc gcggcggttc tcgctggact ttggatcgta gagaagaacc
    40321 tcatagtcaa catttgcaaa ctgctgtgcc agagccatca tcggatctgc gttctccgga
    40381 acgtctgttc tgaaggaacg ggactcatga gcaacatcat ctgctgcgat agcgatgttg
    40441 ttctcctcga aggctgccag cagagccggg ttatcacaga taataccgga agtaacaacc
    40501 tttgttccct gccagtcgca taccggaagc ttctccagct ctgcatttaa ctcgtttaac
    40561 ttagcgatat actcgtcctt taacatgaag tagaatgcct ttaatacggc agatctctta
    40621 gttggagtga ttacatcgca gtgatcggaa gccagcttca cgaatttacg gcgtgctgcg
    40681 cggctctcgt tgtaaacctt gattgcgttc tggatatcgt cgtttgtgat ctctcttccg
    40741 gcaatcttct ccagctcttt ctttacatga ttgtactgat ctactgtgaa ctgaagacca
    40801 aactcctcga aacggttctg cggatgagct aagaagataa cagacatctt atctcccata
    40861 gctacacgga agttctggct catcgggcgg agcgtatcgc agatagttgg agtgatgatt
    40921 ccgtccagac cgtccatggt tccgtctaac agcatctcaa gcgctaactg agcgattgtg
    40981 cagtagaagg ttgcacaata ctctttcgca cggctgatag tctttgtgtt ggaaccccag
    41041 attcccatag gaacgatacc ggcagcataa actaactctt ccggagcgta gtatggcaga
    41101 acgccgacta ctttctttcc ctgagcctta tattcagcaa gctgctgctt tggtgtggca
    41161 gcttttactt taaattcatc taataatgta ttgatactca tttgattatg cctcctttgc
    41221 ctgcttgttt gcttccattg cctctaccag gccctgtaca cgtgtctcat actgtgcggc
    41281 attgaagtta cgaggatctg cctggtctcc gtcgaagcct gcgcatggaa ctcccagatc
    41341 gtctgtgaag cggcgctgca tctctgccat gtatccggac cacggcttac agcttctgtt
    41401 gtagtgaacc agaacgccgt ctaccttatt gtcgcggcag atgccctcac gccagtcaac
    41461 accctgctcg atgcagacag agttcggagc cttgtagtaa gcgcgcgcca tctcgtccat
    41521 accatcgtat acgaagccga atgccggagc gtatacaacg gctgttacgt ttacgccgtt
    41581 tgccttcaga ggcttgaaca gtgcaggcag cttcggccag catggaatac cctcgaacat
    41641 aacgcggtac ttctccggga atggagttgt agtctcgccc ttcttaactg tctcctcaag
    41701 gtccttagct aacagctcga atgcctctgc agtctctacg cgggcacgtg ccgtaacgac
    41761 gtcagccatg tggttgaaca ggtcgaaacc gctgtatgga gctggtttgt actgtaagta
    41821 gtcgcatacc tttaaccatg ccttagctgt acggttagcg tttgcacagg cctgctcaaa
    41881 cttcttctcg tcgaacttct tgcctgtcag ctcctctaac tgcttgatag ccttgtcaaa
    41941 ctgagcgcgc acatacttca cgttctcgtc agctacgtgt acgtcgttgt tgtaaggaat
    42001 atctaccatg ataagcggaa tattgcacat acgggcaatg ttctcgtacc actttgtcat
    42061 acagttgcag atgttgttgc agcagagaac gaaatctggc tgcggaatac gcatctgacg
    42121 gattggggag atagcctcaa gacgtctctc cttctccggt ccgtccggaa gcttctcaat
    42181 ctcaaggagg ttgtcaagct gcaggtaagg agtctgtgtc ttcggatcct taaccggctt
    42241 tccgtcctcg cccattacta cgttgccgtc agcatccttt aatggctttc ctgtgctcgg
    42301 atcgataatg tactcgcctg tctcaggatc gtacttacgg gatacacgga tacctgctgc
    42361 ataagcaagg ctgatacggc agtaaccgca gatatcatta tcatagccca gatcctcagc
    42421 tgcctggcac atcatctcgc cgtaacggtt agctgcgata ccggctgcct ggttctccgg
    42481 gtacataaca tgaaggtcaa atgctgctgc cagctcgcat gggaacttgg aagaggacca
    42541 tcctactaac tctcctcttg cctttgcctc ccgcgcttct ttatggacgt cgtcaactac
    42601 cttgcggagg gcgagtacgc ctggactaac ttgttttgcc ataataatta tcctccattc
    42661 tttctgtgaa atttatttct gacgtgtggc tgcctgatat gcgtaaagtg cggcacccag
    42721 cgcgccatta tactgtgtaa gtggggaaat gtgaatctca cagcccagct cttgctgtaa
    42781 agcgtttacc acgccgctgt tctgagccac gccgcctgtc ataaccacat ccggcacaac
    42841 tccgattctg tgagcaagtc ccgtcacacg gtgagcgact gacttgtgaa ttccgttaat
    42901 aatatcgcac ttatcggttc ccatagccag ctggctgata acctcgctct cagcgaaaac
    42961 ggtgcaggtg gaactgattc caatttcttt cttggacatg gcgcccagtc ttcccagatc
    43021 ttctaccttt acctccagga cacgggccat tacgtctaag aaacggcctg ttccggctgc
    43081 gcacttgtca ttcatctgaa agtttgtcat tgctccgtta tcgatgtgca gaacctttac
    43141 gtcctgaccg ccgatatcga taactgtgtg aactttaggg aacaggaagg aagctccttt
    43201 cgcatggcag gaaagctcgc tcatctgctt tttcgcaatg tcagacaggg agttgcggcc
    43261 gtagccggta gccagagtgt aatccagctg atcctttgtc atccctgcgt ctgccagaac
    43321 ctcctcgata gcgcgggccg gaccgctggt gccggtgcct acgtctacca gagattttcc
    43381 tacaatttct gttccgtctt ttaaaataat gcatttagac gcagtagagc ctacgtcaat
    43441 acccattgtg taaattgcca taatgacctc catatgtaga aggagttcga acggttagac
    43501 tgccctgctc atctcctcac atcattttaa gtataccata tgtactctga aaaagccaaa
    43561 actatttaat gaaactgcat aaaactattg atataacagt aatgtttaat cgtttataca
    43621 gccccatttt cccatgaaaa acgcataaag atccataacc acgataagtc aggtaaaggt
    43681 ttccagttcc tttacccgac tctatcatgc tatcactatc atttatgcgc cctgttcagg
    43741 ctaatttatt atacgttttc gttgcgtttt attacttctt gaatgtctcg aattcacgga
    43801 ttgcccttgg tgtaatcatc tgatggaatg ggcagatgga ctgtggattc tgataagcag
    43861 cctctgtgaa ggcctggatg tatggacgga tgtctgtcat gtctacgatc tcgtctacca
    43921 tacctgtctt tgtgcagtac ttcggacggg acttctctgt gtacatgttg atcatgtcgt
    43981 tcatcttgtc aatgattggc tgaagcggct cgcctgcctt cttagccttt acaagctttc
    44041 tggagtacat agcgttggca gctgtctcgc ctggcattac gtagtactcg caggcgcctg
    44101 ttcccaggga gaatacattt gtattgttgc cctgcggtcc gcccagaacg tagtgggcag
    44161 cagcgctggc cttacggatt gtaacctcta aggacggaag cttggagttc tcgatggagt
    44221 agattaagga ctgtccaaga ccaagtaact cagccttctc tgcctcgtcg cctacatcga
    44281 tacctgttgt atcctgtaac cagattaacg ggattctgtc acgagcgcaa agtgttacga
    44341 actcgttcat cttgattaag ccctgacgat agagctttcc gccgatacct acggagttct
    44401 gcttgtactc cggatagttc atcagaagtc cctgaacgtt ggcaactacg ccgactaaga
    44461 ggccgtttac ctttgcaaga cctgtgatca tctccgggcc gtatcccttc ttgtactcag
    44521 cgaactcgct gttgtcgaag agacgtgcga taacctcgta catatcgtaa ggacgcttct
    44581 ggttcatcgg aacgatgct
//
LOCUS       DBMDUW010000018        43367 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_774_length_43367_cov_3.188531, whole genome shotgun sequence.
ACCESSION   DBMDUW010000018 DBMDUW010000000
VERSION     DBMDUW010000018.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 43367)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 43367)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43367
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_774_length_43367_cov_3.188531"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..649
                     /locus_tag="ACZPCR_05260"
     CDS             <1..649
                     /locus_tag="ACZPCR_05260"
                     /inference="COORDINATES: protein motif:HMM:NF012523.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CatA-like O-acetyltransferase"
                     /protein_id="HIR1230317.1"
                     /translation="FHLIDMDTWERREHYYYYKDFLKVRYNLNIQVDITELLAQVKEQ
                     KLKFYPVFIYIIMRAVNQNREMRMQTDKEGRLGYWDECHPSYTIFHEDDKTFSDIWTE
                     YNEDFTAFYDAVIKDMETYQNQKGIKPKPGKPDNFCPVSCVPWLSFTGYASDTYSDSP
                     MLYPVVLFGRYYEKEGRTFLPLGAAFHHAAADGYHSCRFLNEIQELAETFRLPRR"
     gene            complement(600..1172)
                     /locus_tag="ACZPCR_05265"
     CDS             complement(600..1172)
                     /locus_tag="ACZPCR_05265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230318.1"
                     /translation="MTRKKGKLMTFLWSLIPGAGEMYLGFFKTGVSLMAAFVILLSLS
                     GFLQLNVLSLLAPVVWFYSFFHANNINALPDDEFYALEDDYLVHMEDIRKNSLFFKTH
                     RKFTAACLICFGISVLWSNLYRLLFSHLLPIIALPEQAEEILYSLASAIPQSVVAVAV
                     IAAGILLIRSKSKELNGGEDETSQPAPESH"
     gene            complement(1153..1671)
                     /locus_tag="ACZPCR_05270"
     CDS             complement(1153..1671)
                     /locus_tag="ACZPCR_05270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008395188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230319.1"
                     /translation="MTNKKERKSGHIDPGRPVSSLSREELAHLSSCQFCREQIALQAE
                     KQELLTAPARMKSEILSKLNRPEVQIIAKSNRISKKLELFYFSLRVGTAVLCSLALLS
                     FAPALPGATERPIEIRQEDVKREEDGRFQRPGTPSPKNAGGAVWEASSYVTEQINRLL
                     NLEVFKYDKKER"
     gene            complement(1661..2209)
                     /locus_tag="ACZPCR_05275"
     CDS             complement(1661..2209)
                     /locus_tag="ACZPCR_05275"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1230320.1"
                     /translation="MYRSQGKGGGFINAEKQLEEYIDQYQNLIFSICYKYTENYFDAE
                     DLTQDTFLSAYKSMALFDGAHAKAWLCKIASNKCLDWLKRAGRRTVPTEDEYFTALPS
                     SDSPERDYLEQEVKERLYRCCCSLKEPYRQVALDYYYYEIEIGELVKKTGKPIKTLQT
                     QIYRAKGMLRNLYEKEGLPHDK"
     gene            2417..2875
                     /locus_tag="ACZPCR_05280"
     CDS             2417..2875
                     /locus_tag="ACZPCR_05280"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005541439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008655 - pyrimidine-containing compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HIR1230321.1"
                     /translation="MDRSDKTTALEISREQKEKLIEQAFQALPRAYAPYSHFHVAAAL
                     LCRDGEIYMGCNVENASYPAGICAERSAFSAAVSSGKRQFDAIAIVGGKDGKAQDYCA
                     PCGICRQVMREFVRPDEFLILLAKSPSEYREYTLSQLLPESFGPENLEMA"
     gene            2998..3176
                     /gene="ssrS"
                     /locus_tag="ACZPCR_05285"
     ncRNA           2998..3176
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACZPCR_05285"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     assembly_gap    3363..3372
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <3373..4611
                     /locus_tag="ACZPCR_05290"
     CDS             <3373..4611
                     /locus_tag="ACZPCR_05290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007719093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HIR1230322.1"
                     /translation="AKRYIYWGLTAVCVIAVCIVFWYCIREWKNVSGFLGRLRSIASP
                     IIYGAILAYLISPVYNRVSRAVLKILPAKMKSEKHRQTIAKSMGTIASLFVILAVVSG
                     LIQLIIPQVLDSLRGIQESFPIYLQNLYTWIQKLLADNREIETIVIQNIQTAVEMTEG
                     WLQNAFTRFDMKRLLDFLTGVSSSIFVLINFVKNWLIGLIVMVYLLNIKDHLITQAKK
                     IVYGCLSVRWANHVIEEMRFVHRMFGGFIIGKILDSLIIGVICFVGTSLLHIPYALLV
                     SVIVGVTNVIPFFGPFIGAIPSGILVLLVSPIQCLVLLIWILVLQQFDGNILGPKILG
                     NSTGLASFWVLFSILIFGGLFGFVGMIIAVPGFAVIYDLVNKAVNHSLRMKRLSLKTA
                     DYEGLDYIDEEKKTYIKSKE"
     gene            4658..6931
                     /locus_tag="ACZPCR_05295"
     CDS             4658..6931
                     /locus_tag="ACZPCR_05295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002603836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030435 - sporulation resulting in
                     formation of a cellular spore [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIID/LytB domain-containing protein"
                     /protein_id="HIR1230323.1"
                     /translation="MKSKKMLYWTGAIAAAVVLLIILIVTLDKNGNYVSRALAGKAMA
                     LGMTDREICEEWGDENESFFPASAKGQWYVKYLDYLIGNEYIELPKELKEEDMEDFAA
                     GALTYGEAAFAAEKVEKGLSKALNISKKKYGDPMPKEKWWLFYETFLKKADQERKVQR
                     KNLVLYGTPANVEGAGTWTAYTSEGALEFEGLSLDSYIDWEIQVWVRGTDIIRVEKEI
                     SDKVVYKNAWLVPADGKMEVYIGDIMRSFPLESAVKEETGGVLADVSLTGGKIKKLSL
                     KKDIIQGKVLAVRDNAIEIEGYGNVAVADDFKVYKTYGTVREARKKDILVGYDIQNFV
                     VEDKRICAALLVKSFDARNIRVLLMDTGFKSIFHDTVTLKCQVPMKVTLDDYEFTVEA
                     GEKFTIFDGDERLRRADRRFIVEPEDPTQSIYVTTLERGQGTPAYQGSLEISQEKEGL
                     LLLNDLDVEDYLTKVVPSEMPSSYEMEALKAQAVCARTYAYRQIKANAYSRYGAHVDD
                     STNYQVYNNTVSSERTDAAVKETCGQMVFYGDKAAETYYFSTSCGHTTDGTIWGADQS
                     AVPYLKGVALTDGRTVMKELKDNDSFETFIKDKKVKTYDSSFPMYRWETKFTNRDLEK
                     KVSGIGEIQAVFVTERGTGGIAKKLKIYGSEGEKIVSGESQIRSILGDESLVYRKNDG
                     KTQTGWSSMPSAYIAIDETARDEESGLRTFTVWGGGYGHGVGMSQNGAQQMAREGNDY
                     KDILTFFYEGAEVREEE"
     gene            complement(7008..8228)
                     /locus_tag="ACZPCR_05300"
     CDS             complement(7008..8228)
                     /locus_tag="ACZPCR_05300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002595269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HIR1230324.1"
                     /translation="MKKNVLVGQSGGPTAVINASLYGVVTESLKHDEEIDTVYGMVNG
                     IEGFLADHYLDLSHTLGSRELELLKLTPAAYLGSCRFKLPEDLNSEVYRTLFRKFEAL
                     NIGYFFYIGGNDSMDTVSKLSRYAAAVKSGIRVIGVPKTIDNDLIMTDHTPGFGSAAK
                     YAASMVREIALDASVYQQKSVTIIELMGRHAGWLTAAGVLARKHENDNPLLIYLPESD
                     FSLEQFAADLEAAFKKNPNVVVCVSEGISDASGTFICEYSNEAQIDTFGHKMLTGCGK
                     ILENFIRQQLHVKVRSVELNVCQRCSGMTVSAADIEEAAMAGSAGVQAALNGSTGMMV
                     AFVREDGAEYRLSCSLVDINQVCNQEKTFPREWITDNGTNISPEFLTYALPLIKGEPA
                     RIMEDGLPVYLYRK"
     gene            8595..9530
                     /locus_tag="ACZPCR_05305"
     CDS             8595..9530
                     /locus_tag="ACZPCR_05305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015529350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HIR1230325.1"
                     /translation="MKKMIALMTAGAMAVSMTACAGSDTKETTKTAGTEAGTNTEADT
                     EAAEADEDLTGTITAAGSSALKPLVDDAADMFAEKYPNIAITIDAGGSGEGLKQVSEG
                     TVNIGNSDVPAEDKLEPDQAAELVDHQVCVVTMAPIVNNDVYEAGVTDLTKEQLISIF
                     TGETKNWSEVGGPDEEIVLVTRPTSSGTRATFQKYALDGQEEASNAAMETDDSGVLLQ
                     NVKDTEGAIGYVALSYLTGDAGVSTLAIDGVEPTLENTYSGDYPVWTYEHMYTKGEPD
                     EVTKTFIDYIMSDEYGEQMETLGYGVSSKMTVTEH"
     gene            9652..10590
                     /gene="pstC"
                     /locus_tag="ACZPCR_05310"
     CDS             9652..10590
                     /gene="pstC"
                     /locus_tag="ACZPCR_05310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005338971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HIR1230326.1"
                     /translation="MDRTKGKSMFAKEYFWRDLMTACGLFVIVLTIGIGGFLVYKGSA
                     TFLTYGHSLWEFLGSAEWSPADNSEGGGMVGALIFVTGSLCTCGLALLIAAPFSLGSA
                     IFITDISPRFGEKFYRPVVEIFAGIPSVVYGWVGLTVLVPAIKTVFDRQVGHSILAAG
                     IVLAVMIFPTITTVAADALKAVPKECRMAAYGLGSTRWQTIYKIVVPAAAPGIISGII
                     LGLARAFGEALAVAMVIGQTTALPTSIFSTTKTLTTEIAAQMGNAMEGGEMKSALWSM
                     ALLLFLISLLFIFLIHRVSAARTEDDGRKTAGKGGK"
     gene            10593..11468
                     /gene="pstA"
                     /locus_tag="ACZPCR_05315"
     CDS             10593..11468
                     /gene="pstA"
                     /locus_tag="ACZPCR_05315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005338969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HIR1230327.1"
                     /translation="MAEKRIARARNIDAFMTAVFYAIAIFFFTLLAAFAGKVIIGGLM
                     GATPEMFRFARKGSIGNQLFNTVYLVFISLAVSVPLGVCAGIYLAMYAKEGPVTKFLR
                     MCIETLSSLPSIVVGLFGYLVFLVFFGMGKSLMAGALSVSILTLPLITTTTEDALKGL
                     PAGYYHASLGLGATRWQSIFHVLLPACLPRIMTGVILAAGRGFGEAAALLYTTGSGTS
                     LKWGNWNLSAPTCPLNPFRPAETLSIQIWNLQVNGQDRALANCASAVLMLLVLAFSIG
                     ANVWSSRLKKKHAGE"
     gene            11541..12302
                     /gene="pstB"
                     /locus_tag="ACZPCR_05320"
     CDS             11541..12302
                     /gene="pstB"
                     /locus_tag="ACZPCR_05320"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014078299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HIR1230328.1"
                     /translation="MGEATVKFDISELNLHYGEFHALKNINMKIDANQITAFIGPSGC
                     GKSTFLKTLNRMNDMVENVKIDGTVRLDGTDIFKEMDAITLRHRVGMVFQQPNPFPKS
                     IYDNVAYGPRIFGIKKKDQLDEIVERSLRQAAIWDELKDRLHKSAMGLSGGQQQRLCI
                     ARTLAVEPEVILMDEPTSALDPISTSKIEDLAMELKEKYTIIIVTHNMQQAARISDQT
                     AFFLLGECVEFGDTGEMFAMPKDKRTEDYITGRFG"
     gene            12302..12964
                     /gene="phoU"
                     /locus_tag="ACZPCR_05325"
     CDS             12302..12964
                     /gene="phoU"
                     /locus_tag="ACZPCR_05325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004608581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HIR1230329.1"
                     /translation="MRTNFDRQLNDLEKQLIKMGGLCEEAISLSARALGGEGSAELAK
                     QVHRLEDEINNMEREIENSCMTLLLRQQPIAHDLRNVSAALRMIADLERIGDQADDIA
                     ELVPRIARSGLQSKVHINQMAMAAVSMVMNSVEAFVKEDLALARKVQADDDEVDRLFD
                     CVKEELMKLIEEKGIGAEEALDFLMAAKYLERIGDHAVNVAEWVEYSITGNHKTGETP
                     QI"
     gene            13465..13974
                     /locus_tag="ACZPCR_05330"
     CDS             13465..13974
                     /locus_tag="ACZPCR_05330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C metal-binding domain-containing protein"
                     /protein_id="HIR1230330.1"
                     /translation="MTLLENWRNLAYGDGLDDKKREELWSGYFAIEKGIYEQILSNPA
                     EVVEGTVKELAEKYDTEVLIMTGFLDGINESLKGYENQIETMDENTVVKIEIDPEKLY
                     WNMVEAKAEWLYSLPQWDAILTPEKRKELYRDQKASGTVRNEQKVYPNDPCPCGSGKK
                     YKKCCGKNK"
     gene            complement(14013..14993)
                     /locus_tag="ACZPCR_05335"
     CDS             complement(14013..14993)
                     /locus_tag="ACZPCR_05335"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230331.1"
                     /translation="MKNSFIIADIRRDLIRRLILPLLVIAASLFVLSLTPRDNIFRQR
                     PVNYKSRYENFYNKLLPCVRVRAEDLQYAGLDYYVNGSVSGHYYYTLVDGFCQFYLLD
                     AKNGELPAPSIESLDIHGRLIELKASEYQALLETMASALGWKASSLEEVTSVYAVSAL
                     PSAFYLNFIGRMAANLCLACGLAELFWSLFCLAFPLASPAFRYMADREEACQALQQTE
                     AALSSASKVKRAGKLLLSSSLLLFLDGAGTRLIPTDQIVWTAVRKSRSAVFFCAAASD
                     GKRFRFSCPSYEAARELEQSLRAQNPGIADGDRPPLSRRKHKKKKKHRRS"
     gene            15190..15951
                     /locus_tag="ACZPCR_05340"
     CDS             15190..15951
                     /locus_tag="ACZPCR_05340"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016439335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent DNA methyltransferase"
                     /protein_id="HIR1230332.1"
                     /translation="MESYTSFAAVYDMFMDNIPYEEWASYVISLLREEGIDDGLVLDL
                     GCGTGSLTEILAREGYDMTGIDLSPDMLQIAMEKRMESGRDILYLNQDMREFELYGTV
                     RAIVSICDSMNYLLEKADLVQTLRLANNYLDPGGVFIFDLNTEHKYRDILGQCTIAED
                     REESSFIWDNNFDEETGINEYNLSLFIQEEEDLYRKYQETHYQKAYSLDEVRAAVAEA
                     GMELAAVYDAFTRNAPLEDSERVYVIAREKSKHRK"
     gene            15976..16857
                     /gene="hslO"
                     /locus_tag="ACZPCR_05345"
     CDS             15976..16857
                     /gene="hslO"
                     /locus_tag="ACZPCR_05345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002603752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HIR1230333.1"
                     /translation="MTDYMVRATAAEGQIRAFAATSRETVETARKNHNTSPVATAALG
                     RLLTAGAMMGSMMKGKKDLLTLRIEGDGPIGGLTVTADASGNVKGYAFHPEVMLPPNA
                     QGKLDVGGALGIGVLSVIRDIGLKEPYVGQTILVSGEIAEDLTYYYATSEQTPSSVAL
                     GVLMNKDNTVRQAGGFIIQLLPGASDDMIDRLEEKLKEIKPVTALLDEGKTPEQILDH
                     ILGEFGLEILDKTPVNFYCNCDKKRVEKALISIGKKELQDMIDEGKEIEVNCHFCNRN
                     YAFSVEELKEMLNKAAR"
     gene            complement(17005..17205)
                     /locus_tag="ACZPCR_05350"
     CDS             complement(17005..17205)
                     /locus_tag="ACZPCR_05350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016279324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HIR1230334.1"
                     /translation="MHKGTVKWFNNQKGYGFICDEEGNDVFVHYSGLNMDGFKSLDEG
                     AQVEFEVVNGAKGPQATNVTKL"
     gene            17460..18005
                     /locus_tag="ACZPCR_05355"
     CDS             17460..18005
                     /locus_tag="ACZPCR_05355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002603754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5662 family protein"
                     /protein_id="HIR1230335.1"
                     /translation="MSLHNAVGHFRTITKHKMMVMENCFQVGLYRQGLLHDLSKYSWE
                     EFRTGVRYYQGTRSPNAAEKEVLGYSAAWLHHKGRNKHHFEYWIDFAPDKARGLIGNK
                     MPLKYVIEMVMDRIAASKVYKGKDYTDASPWEYYARGKDYLVMHPETRALLERLLLML
                     KKQGEQKTFAYIRHLLRQGSY"
     gene            complement(18014..19159)
                     /locus_tag="ACZPCR_05360"
     CDS             complement(18014..19159)
                     /locus_tag="ACZPCR_05360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007863260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H-like domain-containing protein"
                     /protein_id="HIR1230336.1"
                     /translation="MITIEKRLELPESYPLSRIGTPDQLLFFDIETTGLSAEHSRLYL
                     IGCVFYRKNEWRMIQWFADTEDSERQLLLAFFEYTKNFSCLIHFNGDSFDIPYLQKRC
                     AFLGLDCGFSHMASFDIYKKIKPFKKLLGLENLKQKTVERFLGISREDRFSGGQLIAV
                     YENYLVSQNQNLYHLLTLHNEEDLKGMPAVLPILSYPDFFRLPAMPAGWKEAFVTDAF
                     GTEEPLIRLLYESPVVLPSPIAAEVPPFSLEAEGNRLCLSVPLVCGEMKRFYPNYKDY
                     YYLIYEDTAVHKSVGEYVERSARKRATAKTCYTKTAGRFLPQPAPIFSEYVKKDYSDR
                     LTYVPCSPELLDRLCPSRRSDSGREPDTKLSLQYLRDVLDWIGLPSS"
     gene            19315..19947
                     /gene="ruvA"
                     /locus_tag="ACZPCR_05365"
     CDS             19315..19947
                     /gene="ruvA"
                     /locus_tag="ACZPCR_05365"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002589645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HIR1230337.1"
                     /translation="MISYIKGTLAEKMEGAAVVEAGSIGYRIFMPASALELLGAVGDE
                     VVVYIYFQVREDAMSLYGFLSRQDREMFKQLIGVNGIGPKAALGLLGTLRPDDLRLAI
                     LTGDAKAISRAPGIGAKTAQRIILDLKDKVSAQEMLSSLAVPAEAAAGRVSQEASAFS
                     AEAAREAVDALVALGYSNLEASRAVKQVELTEDMDAEAVLKASLKFLAFM"
     gene            20032..21045
                     /gene="ruvB"
                     /locus_tag="ACZPCR_05370"
     CDS             20032..21045
                     /gene="ruvB"
                     /locus_tag="ACZPCR_05370"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HIR1230338.1"
                     /translation="MSRRIITTDVTEEDKKIETSLRPQLLGEYIGQERIKGTLKIFID
                     AAKSRNEPLDHVLFYGPPGLGKTTLCGIIANEMGVHMKVTSGPAIEKPGEIAAILNGL
                     SEGDVLFVDEIHRLNRQVEEVLYPAMEDYAIDIMLGKDSSARSIRLELPKFTLVGATT
                     RAGLLTAPLRDRFGIIQKMDFYTPQELKDIVMRSAQVMQVAIEEEGAFEIARRSRGTP
                     RLANRLLKRVRDFAQVKYDGVITKAVADFALDILDVDKLGLDNNDRAILNALIQKFSG
                     GPVGLETLAACLGEDAGTLEDVYEPYLLMNGLINRTPRGRVATEAAYRHLGISMNPAG
                     DRP"
     gene            21114..21617
                     /locus_tag="ACZPCR_05375"
     CDS             21114..21617
                     /locus_tag="ACZPCR_05375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006779859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000917 - division septum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HIR1230339.1"
                     /translation="MSENEKDKKTKAEKTMDSKNYTDVLINGKIYTLGGAEEESYLQQ
                     VASYINEKMSGLQRQPGFQRQSDDYKSVMTCLNLADDYFKERQYAARLENENQNLEKE
                     TYSLKHELVSTQMKLEALHRETEELRRQMKELMLRIPEREEAPAVSETAREAELEQSG
                     DQNSLEG"
     gene            21689..24022
                     /locus_tag="ACZPCR_05380"
     CDS             21689..24022
                     /locus_tag="ACZPCR_05380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HIR1230340.1"
                     /translation="MNSQNRKQEQEKRWQAAVKRGAEILAPAGSFESMKAAVAAGADA
                     VYIGGNKFGARAYADNLDEDRMKEAIDYAHLHGCRIYMTVNTLVKEREMKELYSYLLP
                     YYEQGLDAVIVQDMGVFSFVKRHFPDLDVHASTQMTVTGAPGAALIGRMGASRIVTAR
                     ELSLEEIEEIYRETGAEIESFVHGALCYCYSGQCLFSSLIGGRSGNRGRCAQTCRLPF
                     SVRRGKELLNGKNEKYVLSLKDLCSLDILPDILEAGVFSLKIEGRMKSPRYTAGVVSI
                     YRKYVDQYMKYGRKGYQVDPADRKTLLDLFDRGGQTEGYYREHNGRDMVVLKEKPAFR
                     EENRPLYDYLDKTYVNASLQEPVLGWARAAEGEELRLKLQTDSFGSTIEAEVSGGPVQ
                     TAKNQPMAAERIEKQLNKTGNTPFYFQSLQVETEGNCFIPVQELNELRRNAFEKLETQ
                     ILSQFRRQEPSGHENGEGDGKKAQEGKLQKREISENGTEGEKKGREQAVLHVSLEEPE
                     GLETVLSFRQAAVISIDAAGFPAESWKQTVLNCHERGKECLLLLPHIYRAEAKRYFDA
                     HLRELSEAGFDGAVIRAWEEAELIARWRREGVFFPKITVFDHGLYSFNSLSEEWMEQM
                     LPGETIRFTAPLELNSRELEEKGIRGEELMVYGNIPMMVTAQCLKKTLEGCTGRPELL
                     WMKDRKGKEFPVKNHCRFCYNTIYNSSPLSLLADRSLIERLGPSVLRLSFTTEQPERI
                     REVLKAFSEEFISGTEKGGAPELSGEFTRGHFKRGAE"
     gene            24033..25361
                     /locus_tag="ACZPCR_05385"
     CDS             24033..25361
                     /locus_tag="ACZPCR_05385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007716693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008955 - peptidoglycan
                     glycosyltransferase activity [Evidence IEA];
                     GO_function: GO:0015648 - lipid-linked peptidoglycan
                     transporter activity [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HIR1230341.1"
                     /translation="MANLITNVSKYLMILLIAIYTYYNFRFFGIRDEWGKRRLCRLQN
                     VVMVLIHTLAYLIIYLRTEDEKTLMFFGAQLLFFFLYMGLYRLFYRNLSRLLLNNACM
                     LLSTSFIILTRISMDRAVRQFAIVAVAAAVTMIIPFIMDRAWQLSKIPWVYGSIGLAL
                     LLVVCVMGNTAFGAQLSINIGGFSFQPSEFVKISFVFFVATMFYRSVDFKTIAVTTAV
                     AAAHVLVLVMSKDLGSALIFFVTYLLMLFVATGSWLYLGLGAGSGAAAAVIAYSLFSH
                     VRTRVEAWLDPWSDISGKGYQISQSLFAIGTGGWFGMGLYQGMPSKIPVVEKDFVFSA
                     ISEEMGGIYAICLILICLGCFMQFMMIAAKMQAVFYKLIAFGLGTTYIVQVFLTIGGV
                     TKFIPSTGVTLPFVSYGGSSILSTFIVFNVVQGLYILKRNEEEEDYDEEE"
     gene            25348..26877
                     /locus_tag="ACZPCR_05390"
     CDS             25348..26877
                     /locus_tag="ACZPCR_05390"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002589649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_function: GO:0008955 - peptidoglycan
                     glycosyltransferase activity [Evidence IEA];
                     GO_function: GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HIR1230342.1"
                     /translation="MKKNDPSPEKHGKASASRSRKRSEAAKEQELREAAREKADKNIL
                     RITYAFAALFIGMCLYLGWFLQVDSETVINSSYNARLDRFSDRIVRGKILSSDGKVLA
                     ETQVAEDGTEKRYYPYNYLYVHSVGYSGKNGKTGIESLANFYLLSSHVNLVEKTVNEL
                     QGKKNIGDNVVTTLDSDLQQTASDAMGNRRGAVIAMEPDTGKILTMVSQPNFNANTVD
                     EQWAELTSPENTKAQLVNRATQGLYSPGSTFKIVTALEYLHENPDGMSQFHFDCDGLM
                     EQGEYQIRCYHGESHGSQDLRMSFANSCNGAFSTMGLGLNLTQFNSLASQLLFNSSLP
                     LSLPYKESSFVMGEGADEWERLQTSIGQGKTQITPMHNLMITAAVANGGTLMKPYMID
                     HVENAGGQTVKKFLPEAYGTLMSSEDASVLSGLMTAVVTDGTGSALRGAPYTAAGKTG
                     SAEFETGKETHAWFVGYAPVEDPKIAVCVLLEESGSGGKQAGPVARAVMDKYFEKNPL
                     Q"
     gene            26900..27673
                     /locus_tag="ACZPCR_05395"
     CDS             26900..27673
                     /locus_tag="ACZPCR_05395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HIR1230343.1"
                     /translation="MTQLQMILFLCPIFFFTSFVDAVSGGGGLVALPAYLFTGMPVHS
                     AYACNKVGCVVGSFTSFIRFWKNGLIDMKTALFVGAVTFACSTCGAQIVLHLPDRPLK
                     IMILASMPAVAALIFFQKNYPEVNRTSEITGWKRGGLCLLSGVMMGLYDGILGPGSGT
                     VVMILFTKLLKYNLITASGNTKVILLASTLAASVSYILAGKVIWTVAVPVSVFGMLGG
                     YVGAGMAIKKGTKFIRPMMLGIAALLVIKMAVDLAAGGQ"
     gene            27765..28217
                     /locus_tag="ACZPCR_05400"
     CDS             27765..28217
                     /locus_tag="ACZPCR_05400"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012199368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016817 - hydrolase activity, acting on
                     acid anhydrides [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HIR1230344.1"
                     /translation="MIEATSCGGVVIFRGKILVLYKNYKNKYEGWVLPKGTVEPGEEF
                     KETALREVKEETGVTASIIKYIGKSQYTFNTPQDMVEKDVYWYLMMADSYYSKPQREE
                     YFVDSGYYKFYEAYHLLKFSNEKQILEKAYNEYLDLKRSNLWGSKKYF"
     gene            28399..29883
                     /locus_tag="ACZPCR_05405"
     CDS             28399..29883
                     /locus_tag="ACZPCR_05405"
                     /EC_number="3.4.17.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HIR1230345.1"
                     /translation="MNQSFEKLQNQLEKAMALQTAMVLFEWDNETAAPKEAAERTAVV
                     IGSLSSQYLDIMTGEKLKTALEECSGQMSEMTEVEQAIVRETKEEVEKLERIPADEYR
                     SFAELTARATGIWADAREKKDFSLFAPVLKEIVDYQKRFASYQAKEGQKLYDVMLDNY
                     EKDFGMKELDEFFRVVKEGIVSLLKESAKRSEQIDDSFLSAGYTEEQQEKAARFLAEY
                     VGFDFDRGILAVSAHPFTTNLHNKDVRITTHYLDRIDSSIYSVIHESGHAVYELGIRD
                     DLTQTPAGQGASMGMHESQSRFFENIMGRNRNFWVPIYGNMQEIFGSPLKEVSLDDFL
                     AAVNKTIPGLIRTEADELSYCLHVLVRYEIEKLMIEENAEIDSLPELWNDKYEEYLGI
                     RPKNDGEGILQDIHWSQGSFGYFPSYALGNAFGAQLYHKMKQEMDFDGLLREGRADAI
                     REYLREHIHQYGKLKTSRQLLKDATGEDFNPAYYVEYLTERYGK"
     gene            complement(29921..>30596)
                     /locus_tag="ACZPCR_05410"
     CDS             complement(29921..>30596)
                     /locus_tag="ACZPCR_05410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HIR1230346.1"
                     /translation="DLLYLLSRLLPIEVQPLVYTIIGEIYFKSSAALLSVSSIVTLWS
                     AARGMQGIERGLNRIIGCPKRRGYVISRLINSGYTIVFMAVCVMSLALLVFGTVLQNL
                     ALRFLPFLRFLSPYLISLRSILSLIILAVFFTGLYTFLPYEKMRLKSQLPGAVFSTVC
                     WILFSFAFSLYFKYFSRFSTMYGSLASVAVLMLWLYFCICILFMGAEINFHLSRMEHF
                     RKNRHS"
     assembly_gap    30597..30606
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<30607..30748)
                     /locus_tag="ACZPCR_05415"
     CDS             complement(<30607..30748)
                     /locus_tag="ACZPCR_05415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HIR1230347.1"
                     /translation="MIYFLVHCKQIYDKFVRDEITVYAAQASFFIVLSSVPFIILLLT
                     VLQ"
     gene            30836..32593
                     /locus_tag="ACZPCR_05420"
     CDS             30836..32593
                     /locus_tag="ACZPCR_05420"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003523467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1230348.1"
                     /translation="MKKLLNYLSAYKKEAVLAPLFKMLEASFELLVPLVMAQIIDTGI
                     KNQDLAYILKMGAVLVLLGVIGLACSLTAQYFAARAAVGFGAGVRRDLFRHINRLSYS
                     EIDAQGTATLITRMTSDVNQVQSGVNLTLRLFLRSPFIVFGAMIMAFTIDVKSALIFA
                     AAIPLLSLVVFGIMLISMPLYKRVQRQLDWVMQITRENLTGARVIRAFNREQDEIASF
                     KEEGGLLIRFQIFVGRISALLNPVTYVIVNLAIVVLIYTGAGQVDSGRIPQGEVVALV
                     NYMSQILVELIKLANLIISITKALACAGRISIVFEMESSIADPGEEKGRQVKEGENPS
                     VSGTPRVSFQNVSFSYQGSKEESLSDISFDAAPGEIIGVIGGTGSGKSTLVNLIPRFY
                     DVTKGQVLVNGTDVRAQSLSKLRGQIGVVPQKAVLFKGTIRDNMRWGKEDASDREIEE
                     ALETAQALEVVKSRENGLDAMIFQGGKNLSGGQRQRLTIARALVRKPQILILDDSSSA
                     LDFATDARLRKALRERTGGAAIFLVSQRASALRHADQILVLDDGRLAGKGKHEELLET
                     CPVYREICLSQLSGEEAEQ"
     gene            32608..34386
                     /locus_tag="ACZPCR_05425"
     CDS             32608..34386
                     /locus_tag="ACZPCR_05425"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1230349.1"
                     /translation="MKKDREAKGIFKDTAKSDTIKRVLKHIGAYRWLVLLSLALSAVT
                     VALTLYIPILIGQAVDLITGEGQVDFDGLFRIFGIMAAVILVTAAAQWLMNAINNHIT
                     YRVAMDVREKAFCHLEILPLKYIDGHSYGDVLSRVITDVDQFSDGLLMGFTQLFSGIL
                     TIFGTLVFMFSVNPFIALVVVLMTPLSLLAAGYIAKKTFSMFQEQSEARGEMTSLINE
                     IVENEKVVQAFSYEQKAEERFDKINSRLESCSLRATFFSSITNPATRFVNGLVYASVG
                     IAGAAAAIHGLLSVGQLTSFLNYANQYTKPFNEISGVATELQNAVASAARVFALIDEE
                     PQTPEAEQAIELQEADGRVELSHVAFSYQPDTSLIEDLNLTVEPGKKIAIAGPTGCGK
                     STVINLLMRFYDADSGWIQVSGCDIRQMTRKSLRASYGMVLQETWLKAASIRDNIAYG
                     RPDASMEEIVEAAKKAHAHSFITRMPEGYDTVISEDGGSLSQGQKQLLCIARVMLCQP
                     PMLILDEATSSIDTRTELMVQEAFDRMMEGRTSFIVAHRLSTIRKADQILVMKEGKII
                     EQGNHEELLAKGGFYCELYNSQFAVS"
     gene            34445..34900
                     /locus_tag="ACZPCR_05430"
     CDS             34445..34900
                     /locus_tag="ACZPCR_05430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-thiouracil desulfurase family protein"
                     /protein_id="HIR1230350.1"
                     /translation="MRILVSACLLGENCKYSGGSNRDETVLMWKTKLEQEEKAEFIPI
                     CPEVAGGLPTPRMPAEIRGERVVTRDGRDVTAEYEAGAEEALALSGKHGCRYAVLKER
                     SPSCGSGTVYDGSFSGTLTAGDGIAAALLKKNGVMVVGESQAQKLFEIL"
     gene            35076..35315
                     /locus_tag="ACZPCR_05435"
     CDS             35076..35315
                     /locus_tag="ACZPCR_05435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008396188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1230351.1"
                     /translation="MQICEATVKRIEELRKRERLTLYALAYKTGMPPSTLKCIMNGRS
                     KNPGIVNIKKIAEGFNMTIREFYNSEIFDDLEQED"
     gene            35385..36704
                     /locus_tag="ACZPCR_05440"
     CDS             35385..36704
                     /locus_tag="ACZPCR_05440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004614054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HIR1230352.1"
                     /translation="MEKKSRDQFRTRLGFIVACIGSAVGMGNIWMFPYRTGAFGGAAF
                     LIPYFIFVILLGFSGVLGEMAFGRVMRTGPTGAFGKAMEMRGKRGGRLIGLIPVIGSL
                     GIAIGYSVVVGWFLKYLSAAVSGTLGQVEDMGAYFASLSGSFGSVGWHMLGLALTFLI
                     MLFGVSGGIEKMNKIMMPLFFVFFLILLFRVASLPGAVEGYKYLFIPRWELLGNVKTW
                     VYALGQAFFSLSLAGSGTIVYGSYLSDDADVVTCARNVAFFDTCAALLAGMVVIPAVF
                     AFGLDVTAGPPLMFITLPAVFNQMPAGWLFAVIFFIAVLFAAITSLMNLFETPIEALQ
                     EQFQMSRKAAVACVAFIAAAVGVFIESADAVSMWMDAVSIYMIPLGALLAAVMFFWVC
                     PKGFAREQVQKGREKMLGSWFEPVTRYLFVGLTLGVYVLGILFGGIG"
     gene            36848..37834
                     /locus_tag="ACZPCR_05445"
     CDS             36848..37834
                     /locus_tag="ACZPCR_05445"
                     /EC_number="1.4.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003525383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047850 - diaminopimelate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate dehydrogenase"
                     /protein_id="HIR1230353.1"
                     /translation="MSIRIGILGYGNLGRGVECAVKQNPDMELKAVFTRRDPETVKIL
                     TENAKVYRAEEAERLKDEIDVLILCGGSATDLPVQTPAFARWFNVVDSFDTHANIPQH
                     FEAVDQAASESGHVGIISVGWDPGMFSLNRLYATAVLPEGSNYTFWGKGVSQGHSDAI
                     RRIAGVKDARQYTIPVESALESVRNGENPELTTRQKHTRECFVVAEEGADLAAIEQEI
                     KTMKNYFDEYDTTVHFISQEELDRDHKGLPHGGFVFRSGRTGWEKENSHVIEYSLKLD
                     SNPEFTSSVIVAYARAAYKMSKEGQKGCKTVFDVAPSYLSPESPADLRKKYL"
     gene            37859..39346
                     /locus_tag="ACZPCR_05450"
     CDS             37859..39346
                     /locus_tag="ACZPCR_05450"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HIR1230354.1"
                     /translation="MKRKKWKIHAKQTAALAMAFTLMISGAASAAPIPPDGSGTGQTA
                     QGGNQTSQGGGQNGQQATGPAGPGNGAGNSGSASRLPSLSGTVSTSQSSQTSQNSAQT
                     GSQGSSQAAVPQIKAEGAVLYDATRDQALYEKNADTRYYPASITKIMTALLVLEHCNL
                     NDTVTFSQTAVTNLESGAVTLGVQAGDQFTVEQCLYGLLLKSANEIANGLAEHVSGSI
                     SGFADLMNQKAASLGCTNTHFVNPNGLNDSNHYTTARDMALIADAAFSNPTLCKIAST
                     VNYDFPATASVPSVRKLTMGHKMVNPANSEYYSGIVGGKTGYTSLAGNTLVTCAERNG
                     TRLVAVILKSRQTHYADTRALLDYGFSLVQSGGSGSGTGGPGGGPGSQQGPGGGSASS
                     NPHWVEDSRGWRFVKADGSYAANECMEINGEIYCFKPDSYIVSNDWYQIGGIWYFFRP
                     SGGLAKSRWIETGGKWYYVDGNGSLFTNGTTPDGYRVDADGVWIQ"
     misc_binding    39533..39781
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            39879..40103
                     /locus_tag="ACZPCR_05455"
     CDS             39879..40103
                     /locus_tag="ACZPCR_05455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006779985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6472 family protein"
                     /protein_id="HIR1230355.1"
                     /translation="MFGKGARMSVHSGKKSQASSCETCSNYVYDEDYGYYVCEASLDE
                     DEMAAFLGDRKFQCPYYHINDEYLIVRKQM"
     gene            40147..42798
                     /locus_tag="ACZPCR_05460"
     CDS             40147..42798
                     /locus_tag="ACZPCR_05460"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HIR1230356.1"
                     /translation="MKELEKNYNPADIEARLYQKWLDSKYFHADAERGRREGKKPFTI
                     VMPPPNITGQLHMGHALDNTMQDILIRYKRMQGYEALWQPGTDHAAIATEVKVIDKLK
                     SQGIDKHDLGREGFLEKAWEWKEEYGSRIVNQLHKLGSSADWDRERFTMDEGCSDAVL
                     EVFTKLYEKGYIYKGSRIINWCPVCQTSISDAEVEHEEQDGFFWHINYPIVGEEGRFV
                     EIATTRPETLLGDTAVAVNPEDERYKDLVGKMLKLPLTDREIPVVADEYVDKEFGTGC
                     VKITPAHDPNDFEVGKRHNLPEICIMNDDATISAPGKYFGMDRYEARKAMVEDLQEQG
                     LLVKVVPHSHNVGTHDRCGTTVEPMVKPQWFVRMDEMAKPAVEAIKSGRLKFVPESFG
                     KTYLHWLEGIRDWCISRQLWWGHRIPAYYCDECGEMVVAKTMPEKCPKCGCVHMTQDE
                     DTLDTWFSSALWPFSTLGWPKSTPEYEYFYPTDVLVTGYDIIFFWVIRMVFSGLEQTG
                     KEPFNTVLIHGLVRDSQGRKMSKSLGNGIDPLEVIDKYGADALRMTLMTGNAPGNDMR
                     FYWERVEASRNFANKVWNASRFIMMNVEKAPESQAALSDLTMADRWILSKVNTLAKDV
                     TENMDKYELGIALQKVYDFIWEEFCDWYIEMVKPRLYSDEDTTKAAAIWTLKTVLIQS
                     LKLLHPYMPFITEEIFCNLQEEEPSIMISSWPVYKEEWNFASEENAVETIKEAVRGIR
                     NVRTSMNVPPSKKAKVYVVSEDESLLGIFEHSKVFFATLGYASEVCLQKDKTGIADDA
                     VSAVIPKAAIYMPFAELVDIDKEIERLQKEEERLTKELARVNGMLGNEKFVSRAPEAK
                     IAEEKAKLEKYTQMMDQVKERLAQLSK"
     gene            complement(42933..>43367)
                     /locus_tag="ACZPCR_05465"
     CDS             complement(42933..>43367)
                     /locus_tag="ACZPCR_05465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR-like C-terminal domain-containing protein"
                     /protein_id="HIR1230357.1"
                     /translation="EELDDVLNHFKASDLLSNPALVFTRVFQLVKENSDMVSILIGQN
                     GDINFVNRLKDIVREKCLKDWMELFRPGAGGGRQTSRSSQNTLLDDSAFEAYYSFTVT
                     GCIGLVQYWLDSGLKETPEQLASLVEQIISKGLRMFQPEAGL"
BASE COUNT        11283 a         9698 c        12553 g         9813 t
ORIGIN      
        1 gtttcatttg atcgatatgg atacctggga gcggcgggaa cactattatt attacaaaga
       61 ttttctgaag gtccgctata acctgaatat tcaggtggac attacagagc ttctggcgca
      121 ggtaaaggag cagaagctca aattttatcc tgtgtttatc tacattatta tgagagcggt
      181 caatcaaaac agagagatga gaatgcagac agacaaagag gggcgtctgg ggtactggga
      241 cgaatgccac ccgtcctaca cgatttttca cgaggatgac aaaaccttct ctgatatctg
      301 gacggaatac aatgaggatt ttacggcctt ttacgacgcg gtgataaaag atatggaaac
      361 gtaccagaat cagaagggga ttaagccaaa gccgggaaaa ccggacaatt tctgtccggt
      421 ctcctgcgtg ccgtggctga gctttacagg atatgccagc gatacgtact cagattcccc
      481 catgctctat cctgtggtac tgtttggacg ttactatgag aaggagggaa gaacgtttct
      541 tcctctggga gccgcgttcc accatgcggc tgcagacgga taccactcct gccgctttct
      601 caatgagatt caggagctgg ctgagacgtt tcgtcttccc cgccgttaag ctcctttgac
      661 ttgctgcgga tgagcagaat cccggctgcg attacggcca cggctactac gctctgaggg
      721 atggcgctgg ccaaagagta cagaatttct tccgcctgtt ccggcagagc tatgatcggc
      781 agcaggtggg agaacaggag ccggtacaga ttgctccaca gaacggagat gccaaagcag
      841 atcaggcagg cagccgtaaa tttgcggtga gtcttaaaaa acaggctgtt ttttcggata
      901 tcttccatgt gaaccagata atcgtcctcc agggcataaa attcgtcgtc aggcagggcg
      961 ttaatgttgt ttgcatggaa aaagctgtaa aaccagacga caggagccag caggctcagt
     1021 acgttcagct gcaggaagcc ggacagagac aatagaatca caaaagccgc catcaggctg
     1081 acgcctgtct tgaaaaatcc cagatacatc tccccggctc ctggtatcag agaccagaga
     1141 aacgtcatca gtttaccttt ctttcttgtc atatttaaac acctccaggt ttaataatcg
     1201 gttaatctgt tctgttacat agctggacgc ttcccagacg gcgcctcctg cgtttttggg
     1261 ggagggagtc ccgggacgct ggaaacggcc gtcctcttcc cgcttcacat cctcttgccg
     1321 aatttctatg gggcgttctg ttgctccggg cagggcaggg gcgaaggaga gcagcgccag
     1381 ggaacagaga acggcggttc ccactctgag actgaaataa aaaagctcca gttttttgga
     1441 aattcgattg ctttttgcaa tgatctgtac ctcgggccgg ttcagcttgg acagaatctc
     1501 cgatttcatt ctggcgggag ctgtgagaag ctcctgtttt tcagcctgga gagcgatctg
     1561 ctccctgcag aactggcagg aggacagatg ggcgagttct tctctgctca gggaagaaac
     1621 aggccgcccg ggatctatat ggccgctttt acgctctttt ttatttgtca tggggcagtc
     1681 cctccttttc atagagattt cgaagcattc ccttggcgcg gtaaatctgc gtctgaaggg
     1741 ttttgatggg ctttccggtt tttttaacca gctctccgat ttctatttca tagtaatagt
     1801 agtccagagc cacctggcgg taaggctcct tcagagaaca gcagcagcgg taaagccgct
     1861 cttttacttc ctgttccaga tagtcccgtt ctggggaatc tgacgaggga agagcggtaa
     1921 aatattcgtc ttctgtggga acagtccgcc ttcccgcccg tttcagccag tcgagacatt
     1981 tattggacgc gattttgcag agccacgcct tggcgtgggc gccgtcgaac agagccatgc
     2041 tcttgtaggc ggagaggaac gtgtcctgag tcagatcctc tgcgtcaaaa taattttctg
     2101 tatatttgta gcagatagag aaaatcagat tctgatactg gtcaatatat tcttccagct
     2161 gtttttccgc attgataaaa ccgcctcctt tcccttggct cctgtatatg actggtaatg
     2221 cctttcacag attagaacga agcagagggg gacattactt caaaaatcat ggagacatgc
     2281 gaaacacatg gcggcgttca tggcattatt aaggactgta gcacagaata gaggaaaaga
     2341 caagatttct cttgccccgc agacaagaca gggagtataa ttaagaaaaa agcggctcag
     2401 agagggagga aaaatcatgg atcgcagcga taagacgaca gcgttggaga tttccagaga
     2461 acagaaggag aaactgatag aacaggcgtt tcaggcgctt cccagggcct atgcgcctta
     2521 ctctcatttt catgtggcgg cggctctttt gtgccgggac ggagagattt atatgggctg
     2581 caatgtggag aacgcctcct atccggccgg catctgcgca gagcgcagcg cgttttctgc
     2641 ggcagtcagc agcggaaagc ggcagtttga cgccatcgcc attgtaggag gaaaagacgg
     2701 aaaggcgcag gactactgcg cgccctgcgg gatctgccgc caggttatgc gggaatttgt
     2761 ccgtccggac gaatttttga ttctgttagc caagtcgcct tccgaataca gggagtacac
     2821 cttaagccag cttctgccgg agagcttcgg gccggagaat ctggaaatgg cctagcacag
     2881 atattttagg caggccggga acacggcaga tcagaaaaaa tggcaggaag accagaaaaa
     2941 aatggaactt gaaaaactga cgcaagtgtt gtataatggc cttacaacaa aagaaagtaa
     3001 ttcctgggat gttcgataac tcttactttt tttgaaccta catttgacat aacgggattc
     3061 caatattttt aaacggatgt caggcctcct tgagtggaag gcagatgttt aagtgaggtt
     3121 gcccacctgg cgcggctagg agtcaatttg gtaagagccg gcattttggg gttactaatg
     3181 aaaaaagcag cgagaaatcg ctgctttctt tactttacga aggagaccag gttttctgcg
     3241 ggaagaaaat tcgcgggcgt ttcttgcaaa agaaagtcag gtccgctata ctgtacagga
     3301 gagaaaccgg agatccgcgt aattgtttgg aggaatgact agactatgaa agacaacaac
     3361 gcnnnnnnnn nngcaaaacg gtatatttac tgggggctta cggctgtctg cgtcattgct
     3421 gtgtgtattg tattctggta ctgcatcaga gagtggaaga atgtaagcgg ctttttaggc
     3481 aggctgcgtt ccatcgcgtc gccgattatc tacggagcca tactggctta tctgatcagc
     3541 ccggtttata acagagtgtc cagggcagtc cttaagattc tgcctgcgaa gatgaaaagc
     3601 gaaaagcaca gacagaccat cgccaagtcc atgggaacga tcgccagcct gtttgtgatt
     3661 ctggccgtcg tgtcaggact gattcagctg attatcccac aggttctgga cagcttaaga
     3721 ggaattcagg agtcgtttcc tatctatctt cagaacctgt acacgtggat tcagaagctg
     3781 ttagccgaca accgggagat tgaaaccatc gtgatccaga atattcagac agcggtggag
     3841 atgacggaag gatggctgca gaacgctttt acgagatttg atatgaagcg gcttctggac
     3901 tttctgacag gcgtgtcgag cagtatcttc gttctgatta attttgtgaa aaactggctg
     3961 atcggcctga ttgtcatggt ctatctgctg aatattaagg atcatctgat cacccaggcg
     4021 aaaaaaattg tttacggatg cttaagcgtc cgctgggcga accatgtgat tgaggagatg
     4081 cggtttgtcc acaggatgtt cggcggcttt attatcggaa agattctgga ctccctgatt
     4141 atcggcgtga tctgctttgt gggaacgagt ctgctccaca tcccttacgc gctgcttgtc
     4201 agcgtaattg tgggagtgac caatgtgatt ccgttcttcg gaccatttat cggggccatc
     4261 ccaagcggca ttttagtgct tctggtaagc ccgatccagt gtctcgttct gctgatatgg
     4321 atcctggttc tgcagcagtt tgacggcaat attctgggac cgaaaattct cggaaactct
     4381 accggcctcg caagcttctg ggtgctgttc tccattctga tcttcggagg cctgttcgga
     4441 tttgtgggaa tgattatcgc agttcccggc tttgccgtta tctatgatct ggttaataag
     4501 gcggtcaacc actccctgcg catgaagagg ctgtcgctga agactgcgga ctatgaggga
     4561 cttgattaca ttgacgagga gaaaaagacc tatattaagt cgaaggaata gtacggctgt
     4621 gcagaagggt atgatgcagc aaaggatagg agaatccatg aagtcaaaga aaatgcttta
     4681 ctggaccggc gccattgccg ccgccgtagt cctgttgatc atattgattg taacgctcga
     4741 taaaaacggc aactatgttt ccagggcgct ggccggaaaa gccatggctc tgggcatgac
     4801 agatcgggag atctgcgagg agtgggggga tgagaacgaa tccttctttc cagcctcggc
     4861 caaggggcag tggtatgtga aatatctgga ctatctgatt ggaaacgaat acatagagct
     4921 gccaaaagag ctgaaagagg aagatatgga ggattttgcc gctggcgcgc tgacctacgg
     4981 ggaggcggca ttcgcggctg aaaaggtaga aaagggactt tccaaggcat taaacatttc
     5041 taaaaaaaag tacggggatc ccatgcccaa ggagaagtgg tggctgtttt acgaaacctt
     5101 cctcaagaag gcagatcagg aaagaaaggt tcagagaaag aatcttgtgc tctacggaac
     5161 cccggccaac gtggagggag cgggaacctg gaccgcctac acaagcgagg gggccctgga
     5221 gttcgagggc ctgtccctgg actcctatat tgactgggag attcaggtat gggtccgggg
     5281 aacggatatc atccgtgtgg aaaaagagat ttcagacaaa gtcgtttata agaacgcctg
     5341 gctggttccg gcagacggaa agatggaggt ctacattgga gacattatga gaagctttcc
     5401 gctggaatcg gcggtgaagg aggagaccgg cggcgttctg gccgacgtgt ccctcacagg
     5461 gggaaagatt aagaagctct ctctgaaaaa agatatcatc cagggcaagg tactggccgt
     5521 cagagacaat gccattgaga ttgagggcta tggaaatgtg gctgtcgcag atgatttcaa
     5581 ggtgtacaag acatatggca cggtgcggga ggccaggaaa aaggatattt tagtaggcta
     5641 cgacatccag aatttcgtag tggaagataa gagaatctgc gccgcccttc tggtgaagag
     5701 ctttgacgcc agaaatatcc gggtgcttct catggataca ggcttcaaat ctatttttca
     5761 cgatacggtg acgctgaaat gccaggtgcc catgaaggta actctggacg actatgagtt
     5821 taccgtggaa gcgggggaga agtttacgat ttttgacgga gacgagcggc tgaggcgggc
     5881 agacagacgg tttattgtag agccggagga tccgacacag tcgatctatg tgaccaccct
     5941 ggagaggggg cagggcactc cagcctacca gggcagtctg gagatcagcc aggagaagga
     6001 gggacttctg cttctcaatg atctggatgt ggaggattac ctgacaaagg tggtgcccag
     6061 cgagatgccg tcctcctatg agatggaggc gctgaaggcg caggcagtct gcgccagaac
     6121 ctatgcgtac cgtcagatta aggccaacgc ttacagccgg tacggcgctc atgtggatga
     6181 cagcaccaat tatcaggtgt acaacaatac ggtttccagt gagcggacgg acgcggcggt
     6241 gaaggaaacc tgcggccaga tggtgtttta cggggataag gcggctgaga cctactattt
     6301 ttccacctcc tgcggccata ccacagacgg aacgatatgg ggagcggatc agagcgctgt
     6361 tccgtatctg aagggagtag ccctgacgga tggccgaacc gttatgaagg aattgaagga
     6421 taatgattcc tttgagacat ttatcaagga taagaaggtg aaaacctacg attcttcctt
     6481 ccctatgtac cggtgggaga ccaagtttac aaaccgggat ttggagaaaa aggtgagcgg
     6541 cattggagag attcaggcgg tcttcgtgac agagcgggga accggcggaa tcgccaaaaa
     6601 gcttaaaatc tacggaagcg agggggagaa aatcgtcagc ggcgagagcc agatcagaag
     6661 tattctggga gacgaatccc tggtatatcg gaaaaacgat gggaaaaccc agactggctg
     6721 gagcagtatg cccagcgctt acattgccat agacgagaca gccagagacg aggaaagcgg
     6781 ccttcggacc ttcaccgtat ggggcggagg ctacggccac ggcgtaggca tgagccagaa
     6841 cggcgcccag cagatggcca gagagggaaa cgattacaag gatatcctga ccttcttcta
     6901 tgagggggcc gaggtaagag aagaagaata gtataattta agaagaggaa acattttcct
     6961 gctccgcttt aagctgcaca aaatgtctcc tcttttttct ttttctttta ttttctgtac
     7021 aggtagacgg gaaggccgtc ttccatgata cgggcgggct ctcctttgat gagcggaaga
     7081 gcgtaggtta agaattccgg gctgatattg gtgccgttat ctgtaatcca ctctctgggg
     7141 aaggtctttt cctggttgca gacctgattg atgtctacca gagaacagga aaggcggtat
     7201 tctgcgccat cctctctgac aaaagctacc atcatgccgg tagatccgtt taaggcggcc
     7261 tgaacgcctg cagagcctgc catggcggct tcctcgatat ctgctgccga gacagtcatg
     7321 ccggagcagc gctggcatac gttcagttcc acggaacgca cctttacatg aagctgctgg
     7381 cggatgaaat tctccagaat ttttccgcag ccagtcagca ttttatggcc gaaggtatcg
     7441 atctgggctt cgttggagta ttcgcagata aaggttccgc tggcgtcgga gattccctcg
     7501 gacacacaga caactacgtt tggatttttc ttaaaagcgg cttccagatc tgcggcaaac
     7561 tgctccaggg aaaaatcgga ttccggcaga tagatgagaa ggggattgtc gttctcatgc
     7621 tttctggcca ggacgcctgc ggcggtgagc catccggcgt ggcggcccat cagctctatg
     7681 atagtgacgg atttctgctg gtagacagac gcgtccagcg cgatttcacg gaccatggaa
     7741 gctgcatact tggcggcgct tccaaaaccg ggcgtgtgat ccgtcataat taaatcgttg
     7801 tcaatggttt tcggcacgcc gatgacgcgg ataccgcttt ttacagccgc agcgtagcgg
     7861 gacagcttgc ttacggtatc catggagtcg ttgccgccaa tgtagaaaaa gtatccgata
     7921 tttaaggctt caaattttct gaacagagtc cggtacacct ctgaatttaa gtcctccggc
     7981 agcttaaaac ggcaggaacc cagataggcg gcgggagtca gctttaaaag ctccagttcc
     8041 cggcttccaa gagtatggga caaatccagg taatgatcgg ccaggaatcc ctcgattcca
     8101 ttcaccatgc cgtagaccgt atcgatctcc tcatcatgct tcagactttc tgtgacgact
     8161 ccgtaaagac ttgcgttaat tactgcagta ggacctccgg actggcctac aagtacgttt
     8221 ttcttcattg taacagctct ctcctttatg ttttctggca gatgcccgta aatgaatccc
     8281 gcggacggca gccgcactta ttttataata ggaagccgga tatttcaacc gtttccctgt
     8341 atttcagggg agtttaggag aaaaagggaa gaaattccga ttgggaaatg aaaaatttgt
     8401 gtaaaacaaa caggaaaaaa tatcacaaac ttttgacaaa agcagtattt tagattttac
     8461 aaaccaagag ctatactata gctgttcccg agggaacgaa agaaaacaga gagctgttaa
     8521 gatgcagccg agcgaaaacg gaaaaaacgc acagagacct ggacgggtcc gcgagagaag
     8581 aggagaataa aattatgaaa aaaatgattg cgcttatgac agcaggagct atggcagtga
     8641 gcatgacagc atgcgcaggt tccgacacaa aggagacgac aaaaacagcc ggtacagagg
     8701 ctggcacaaa tacagaggca gacacagaag ccgctgaggc agacgaggat ctgacaggaa
     8761 ccatcacagc ggcaggttcc tctgcattaa agccattagt agacgacgcg gcagatatgt
     8821 tcgcagagaa atatccgaac attgccatca ccatcgacgc aggcggttcc ggagagggct
     8881 taaagcaggt gtccgaggga acggttaaca ttggaaattc cgacgttccg gcggaggaca
     8941 agctggagcc ggatcaggcg gcagaactgg tagatcacca ggtatgcgtc gttaccatgg
     9001 cgccaatcgt aaacaacgac gtctacgagg caggcgtgac agacctgaca aaggagcagt
     9061 taatcagcat ttttacaggg gagacaaaga actggagcga ggtcggcgga ccagacgaag
     9121 agattgtgct tgtgacacgc cccacatcct ccggtacgag agcaactttc cagaaatacg
     9181 ccctggacgg ccaggaggag gcttccaacg cggctatgga gacagacgat tccggagttc
     9241 ttctccagaa tgtaaaggac acagagggag caatcggata cgttgcctta tcttacctga
     9301 caggagacgc gggagtgtct actctggcaa tcgacggagt ggagccgact ctggaaaata
     9361 catacagcgg agattatccg gtatggacct atgagcatat gtacacaaag ggcgagccgg
     9421 acgaggtgac aaagacgttt atcgactaca ttatgtctga cgagtacggc gagcagatgg
     9481 agacattagg ctacggcgta tcctctaaaa tgacagtaac cgagcactaa gagagaaagc
     9541 gccagctttt gcagcagata aggataaagg gggagagccg gggagtgtcc tttggcttct
     9601 ccctttttga gagcttctat tctgggactg ctgagcgggc caggaggata tatggatagg
     9661 acaaaaggaa aaagcatgtt tgccaaggaa tatttctggc gggatctgat gacggcctgc
     9721 ggtttatttg tgattgtcct cacaatcgga atcggaggat tcctggtata caagggttcc
     9781 gctacgtttt taacctacgg ccattccctc tgggagttct taggctccgc agagtggtct
     9841 ccggctgaca attcagaagg cggaggaatg gtcggagcgc tgatttttgt gacaggctct
     9901 ctgtgtacct gcggcctggc ccttttaatc gcagctccct tttcgctggg atccgccatt
     9961 tttatcacag atatttcgcc caggttcgga gaaaaatttt accgtccggt tgtggagatt
    10021 tttgcaggga tcccctcggt tgtatatgga tgggtaggtc ttaccgtgct ggttccggcc
    10081 attaaaacgg tgttcgaccg gcaggtggga cactcgattc tggcggcggg aatcgtgctg
    10141 gcggtaatga ttttcccgac catcactacg gtagccgcag acgcgctgaa ggcggttcct
    10201 aaggagtgcc gcatggcggc ctacggcctg ggttctacca gatggcagac gatttataag
    10261 atcgtggttc cggcggcggc tccaggcatt atttcaggca ttattctggg acttgccaga
    10321 gcgttcggag aggccctggc ggtagccatg gtaatcggac agaccacggc tcttccaacc
    10381 agtatttttt caactacaaa gacgctcacc acagagatag cggcccagat gggaaacgcg
    10441 atggagggag gagagatgaa atccgccctc tggtccatgg ctctgctttt gtttctcatt
    10501 tctctgctgt tcattttcct gattcaccgt gtctctgcgg cgcggacaga ggatgacggc
    10561 agaaaaactg ccggaaaggg aggaaaataa gtatggcgga aaagagaatt gcccgcgcca
    10621 gaaatataga cgcttttatg acagcggttt tttatgccat tgccattttt ttcttcacgc
    10681 tgctggcagc gtttgcggga aaggtgatta ttggaggact gatgggggcc acgccggaga
    10741 tgttccggtt tgccagaaag ggcagcattg gaaatcagtt gtttaacacg gtgtatcttg
    10801 tatttatttc ccttgccgtg tctgttcccc tgggagtctg cgcaggcatt tacctggcca
    10861 tgtacgccaa ggaaggacct gtgacaaagt ttttgagaat gtgtatcgaa accctgtcgt
    10921 ccctgccgtc catcgtggtg ggactgttcg gatacctggt atttcttgtt tttttcggaa
    10981 tgggaaagag cctgatggcg ggagcgctgt ccgtgtcgat tctgacgctt cctctgatta
    11041 ccaccaccac agaggacgcg ctgaaaggac ttccggcggg atattaccac gccagcctgg
    11101 gactgggagc caccagatgg cagagtattt ttcatgtgct tctgccggcc tgtctgccga
    11161 gaattatgac gggcgttatc ctggcggctg gcagaggctt cggagaggcg gcggcccttc
    11221 tctacactac aggatctggt acctcattaa agtggggcaa ctggaatctg tctgcgccca
    11281 cctgtccatt aaaccccttc cgcccggcgg aaactctgtc tatccagatc tggaatctcc
    11341 aggtaaacgg acaggatagg gccctggcca actgcgcctc cgccgtgctg atgctgttag
    11401 tgctggcgtt cagcattggc gctaacgtgt ggagcagcag gctgaaaaag aagcacgcgg
    11461 gagagtaggg cctgcgcagg aaatatcatt cataagcagg aaactaaacg cagatcacag
    11521 tacatggaaa ggaaagaagc atgggagaag cgacggtaaa atttgatatc tcagagctga
    11581 atctccacta cggagagttc cacgccctga aaaatataaa tatgaagata gatgcaaacc
    11641 agatcacagc ctttatcggg ccgtccggct gcggaaaatc tactttttta aaaacgctca
    11701 accggatgaa cgacatggtg gagaacgtaa aaatcgacgg aacggtccgc ctggacggaa
    11761 ccgatatttt taaggagatg gatgccatca cgctgcgcca cagagtggga atggtattcc
    11821 agcagccgaa tccgtttccg aaaagcattt acgacaacgt ggcctatggg ccgaggatct
    11881 tcggaattaa gaagaaggat cagctggatg agattgtgga gcggagcctc cgccaggcgg
    11941 ctatctggga cgaattaaag gatcgcctcc acaagagcgc catggggctg tccgggggac
    12001 agcagcagag gctgtgcatt gccagaactc tggccgtaga gcctgaggtg attctgatgg
    12061 acgagcccac ctccgccctg gatccgattt ctacctccaa gatcgaggat ctggccatgg
    12121 aactgaaaga aaagtacacg attattattg tcacccacaa tatgcagcag gctgccagaa
    12181 tctccgatca gaccgccttc ttcctgctgg gagagtgcgt ggaattcggc gacaccgggg
    12241 aaatgttcgc catgccgaag gacaagcgga cagaagatta cattacaggg aggtttggtt
    12301 gatgagaacg aatttcgaca gacagttaaa cgatctggaa aaacagctga tcaagatggg
    12361 cggactgtgc gaggaggcca tctccttatc tgccagagcg cttggcggcg agggcagcgc
    12421 ggagcttgcg aagcaggtgc accggcttga ggacgagatc aacaatatgg agcgggaaat
    12481 agaaaacagc tgtatgacgc tgcttctgcg ccagcagccc attgcccacg atctgaggaa
    12541 cgtatcggcg gctcttcgga tgatcgcaga cctggagcgg attggagatc aggcggacga
    12601 tatcgcagaa ttggtgccga ggattgccag aagcggactt cagagcaagg ttcatattaa
    12661 ccagatggcc atggccgccg tttccatggt tatgaacagt gtggaggcct tcgtaaaaga
    12721 ggatctggct ctggccagaa aggtgcaggc agatgacgat gaggtagacc gcctgtttga
    12781 ctgcgtcaaa gaggagctga tgaagctgat tgaggaaaag gggatcggag cggaggaagc
    12841 tctggacttt ctgatggccg ccaaatatct ggaacggatt ggcgatcacg cggtcaatgt
    12901 ggcggagtgg gtggagtatt ccattaccgg aaaccataaa acgggggaaa cgccccagat
    12961 ataaattgat tcagccagcg ggcagcggtt cacataagga tcgctgcccg ttttctgcgt
    13021 gaaatattga caagaaaaaa ttctgctctg cagaattctc cgcctgcggc gggctgctca
    13081 gcagcataat accgcaccgc cgcagtgtga ttcctgcgga acatttttta tttcatagga
    13141 cgcgcttttt cctatgaaat aaaaaaatac cccgcctgct gcacaaggcc aacaagcgag
    13201 gtattaaaaa ggggaggata agtattcaaa actttctctt ttgttgatat tactattatg
    13261 gacaaaaaga gagaggatat acaggaaaga taaattttta tgatcattcc agatcttccc
    13321 ctattgtaaa actgtattgg caaagcgaaa ttcattgcaa aatgtcagga cttgttatat
    13381 actgataggg aactttcccg tatccagggc gcttgcagcc aggaggtggg aatggttgat
    13441 tagaaaaaga atggagcggt tattatgaca ttactggaga actggagaaa cctcgcatac
    13501 ggcgacggac tcgacgataa aaaaagagaa gaactgtggt ccggatactt tgcgattgag
    13561 aagggcattt acgagcagat tctttccaac cctgcggaag tggtagaggg aaccgtgaag
    13621 gagctggctg agaagtacga cacagaagtt ctgattatga caggcttctt agacggaatc
    13681 aacgagagct taaagggcta tgagaatcag atcgagacta tggacgagaa cacggtagta
    13741 aagattgaga tcgacccaga gaagctctac tggaatatgg ttgaggctaa ggcagagtgg
    13801 ctgtacagcc ttccgcagtg ggatgcgatt ctgactcctg agaagagaaa agagctctac
    13861 agagaccaga aggcttccgg tactgtacgc aacgagcaga aggtttaccc gaacgatcca
    13921 tgtccatgcg gcagcggaaa gaagtacaag aagtgctgcg gaaagaataa ataaaagaat
    13981 aaataacagg aaaaagcaca gacgctgtga tatcagctgc gcctgtgctt tttctttttt
    14041 ttatgctttc ttctggaaag aggaggccgg tctccatctg caatccctgg attctgcgct
    14101 cttaaactct gttccagctc tctggcggct tcataggagg gacaggaaaa gcgaaagcgc
    14161 tttccgtcgg aggccgccgc gcagaagaaa acggcggagc gggatttcct gacagccgtc
    14221 cagacaatct gatcggtggg aatcaggcgc gttccggctc cgtcgagaaa cagaagcagg
    14281 gaggaggaca gaagcagttt tccggcccgc ttgactttgc tggcggagga gagagccgcc
    14341 tccgtctgtt ggagagcctg gcaggcctcc tctctgtctg ccatgtaccg gaacgctggg
    14401 gaggccagcg gaaaggccag acagaacaga gaccagaaca gctcggccag cccgcaggcc
    14461 agacagagat tggctgccat tcttcctatg aaattcaggt agaaggccga aggaagggcg
    14521 gaaaccgcat agacggaggt tacctcttcg agagagctgg ccttccatcc aagagccgac
    14581 gccatcgttt ccagaagagc ctgatactct gaagccttca gctcgatcag cctcccgtgg
    14641 atatccaggc tttcaatgga gggagcggga agctctccgt tttttgcgtc taacaggtag
    14701 aactggcaga agccgtccac cagggtgtag tagtaatggc cgcttaccga accattgaca
    14761 taatagtcca gcccggcgta ctgcagatcc tcggccctga cgcggacgca ggggagaagc
    14821 ttattgtaga aattttcata tcggcttttg tagtttacag gccgctgccg gaaaatattg
    14881 tccctgggag tcagggagag aacaaacaga gaggcggcta tgaccagaag cggcagaatc
    14941 agtctccgga tcagatcccg ccgtatatct gcaataataa agctgttttt cataaatcaa
    15001 atcttccaat cttaacgtcc ctgtgagaga cgctgtttcc tgccgccagc agactttttg
    15061 cacgccagca gacagcacca taagtatacg caaaaaaact ccaataatca ataaccggtt
    15121 gcttttcaca tgaaatattg ttatgattta atacgaaaaa gctacaatgt tatgagcagg
    15181 aggaacactt tggaatcata taccagcttt gcggcagttt acgatatgtt tatggacaat
    15241 attccctatg aggagtgggc atcctatgtg atttcgcttc tcagggagga ggggattgac
    15301 gacggcctgg ttctggatct gggatgcgga accggaagcc tgactgagat tctggccaga
    15361 gagggctacg acatgacggg aatcgatctg tcgcctgaca tgctccagat tgccatggag
    15421 aagcggatgg aatccggccg ggatattctt tacctgaatc aggatatgag ggagtttgag
    15481 ctttatggga cggtgagagc cattgtcagc atctgcgact ccatgaatta tctgctggag
    15541 aaggcggatt tggtgcagac gcttcggctg gccaacaact acctggatcc aggcggcgtt
    15601 tttattttcg atctgaatac agagcacaag tacagagata ttctgggaca gtgtaccatc
    15661 gccgaggaca gggaagagag cagtttcatc tgggataata atttcgacga ggagacgggg
    15721 atcaatgagt acaatctgag tcttttcatc caggaggagg aagacctcta tcgaaaatat
    15781 caggaaaccc attatcagaa ggcctacagc ctggacgagg tgagagctgc tgtggcggag
    15841 gcagggatgg agcttgcagc cgtctacgac gcctttacca gaaacgctcc gttagaggac
    15901 agcgagcgcg tctatgtgat cgccagagag aagagcaagc atcgaaaata ggacagcaga
    15961 aaggaagaga aagcaatgac agattatatg gtaagagcta cggcggcaga ggggcagatc
    16021 cgcgcctttg cagccacctc cagagagacg gttgagacag ccaggaaaaa tcacaataca
    16081 agcccggtag ctacggcggc tctgggaaga cttttgacag ccggagcgat gatgggcagc
    16141 atgatgaagg ggaagaagga ccttttaact ctgcggattg agggagacgg ccctatcgga
    16201 ggtctcactg tgacagcgga cgcctctgga aatgtgaagg gctatgcgtt ccatccggaa
    16261 gtaatgctgc ctcccaacgc ccaggggaag ctggacgtag gcggtgccct gggaatcggc
    16321 gtgttaagcg taatccgcga tatcggcctg aaagagccgt atgtgggcca gaccattctg
    16381 gtcagcggag agattgcgga ggatctgacc tactactacg ctacttcgga gcagacgcct
    16441 tcctcagtcg ccctgggcgt cctgatgaat aaggacaaca cggtacgcca ggcgggcgga
    16501 tttatcatcc agctgcttcc gggcgcttcc gatgacatga ttgacaggct ggaggaaaag
    16561 ctgaaggaga ttaagcctgt cacagctctg ttagatgagg ggaaaactcc ggaacagatt
    16621 ttagatcata tattaggaga gtttggcctg gaaattcttg ataagacgcc agtgaatttc
    16681 tactgcaact gcgataagaa gcgggtggag aaggcgctta tcagcattgg aaagaaagag
    16741 cttcaggaca tgattgacga gggaaaagag attgaggtca actgccattt ctgcaaccgc
    16801 aattatgcct tttccgtgga ggaactgaaa gaaatgttaa ataaagcggc ccgttaaggc
    16861 gccgcagcca tcgaaaaaag gactatcagc ggaaactgac agtccttttt ttaatcatct
    16921 acttaattca aatatagctt attcacaaaa tataggtgta aatatataga ttggaaacag
    16981 gtacactgga aagaggtata atgattagag cttagttaca ttagtagcct gtggtccctt
    17041 ggctccgttg actacctcga actctacctg agcgccctcg tcaagggatt tgaaaccgtc
    17101 catgttcaga ccggaatagt gaacgaaaac gtcgttgcct tcctcgtcac agataaatcc
    17161 gtagcccttc tggttattga accactttac tgtacctttg tgcataataa acctccaaga
    17221 aaatgaaaaa tgttaaggct tgactattaa aagcctgcct caagaatatc atagtttgaa
    17281 aggggtgtca aatcatttcg gaatctggcc aaaaaaaatc aaaacaaatc tcagctggaa
    17341 ttggcatttg cgccgggaag gcaaatgtgt tagaattatc tgtagttttc cggcctggaa
    17401 tcgtccggtg aaaggacgtt ccggccagag gttaaggatg aagaaggagg atgaggggaa
    17461 tgagcctgca caatgcagtc ggccattttc ggaccattac aaaacataaa atgatggtga
    17521 tggaaaactg tttccaggta gggctttaca gacaggggct gcttcacgat ctgtcgaagt
    17581 attcctggga ggagtttcga accggagtca ggtactatca ggggacgaga agtcccaacg
    17641 cggcggaaaa ggaggttctg ggatattctg ccgcctggct tcaccacaag ggaagaaata
    17701 agcaccactt tgaatactgg atcgactttg cgcctgataa ggccagagga ctgataggaa
    17761 ataagatgcc gctcaagtat gtgattgaga tggtgatgga tcgaatcgcc gcctccaagg
    17821 tctacaaggg aaaggattac acagacgctt ccccctggga atattatgcc aggggaaagg
    17881 attatctggt gatgcatccg gagacgcggg cccttttgga acggcttctc ctgatgttaa
    17941 aaaagcaggg agagcagaaa acatttgcct atatccgcca tctgctgcgg cagggcagct
    18001 attaaaacga gcttcaggag ctggggaggc cgatccaatc cagaacatcc ctcagatact
    18061 ggagagacag cttcgtatcc ggctctctgc cggaatctga gcgcctggag gggcacagtc
    18121 tgtctaacag ctctggactg cagggcacat aggtgagacg gtcagagtag tcctttttga
    18181 catattctga aaagatggga gcgggctgag gcaggaatct tcccgctgtt ttggtatagc
    18241 aggttttggc tgtggccctt tttctggcgg accgttccac atactctccg acgcttttat
    18301 ggacggcggt atcctcatag attaagtagt aataatcctt ataatttgga tagaaccgtt
    18361 tcatttctcc gcagaccaga ggaacgctca ggcacaggcg gtttccctct gcttccaggg
    18421 aaaagggagg gacttctgcc gctatgggag aggggagaac gaccgggctt tcatagagca
    18481 gacggatcag aggctcctct gttccgaagg cgtcggtgac aaacgcttcc ttccatccgg
    18541 caggcatagc gggcagccgg aagaaatcgg gataggagag gatgggcaga acggctggca
    18601 ttcctttcag atcctcttcg ttgtggagcg tcagaagatg gtacagattc tgattttggg
    18661 aaaccagata attttcatac accgcaatga gctgcccgcc ggaaaaacga tcttccctgc
    18721 tgatgcccag aaaccgttcc acggttttct gcttcagatt ctcaaggccc agaagttttt
    18781 taaagggctt tatttttttg tagatatcaa agctggccat atgggaaaag ccgcagtcaa
    18841 ggcccaggaa ggcgcaccgc ttttggaggt aaggaatgtc gaagctgtcc ccgttaaagt
    18901 gaatcagaca ggagaagttc ttcgtatatt caaagaaggc gaggagcagc tggcgttcgc
    18961 tgtcctctgt gtcggcaaac cactgaatca tccgccattc attcttcctg taaaagacgc
    19021 atccgatcag atagagtctt gaatgttctg cggacagccc cgttgtctcg atgtcgaaaa
    19081 agagcagctg atccggcgtg ccaatgcggg agagtgggta agattccggc agctccaggc
    19141 gtttttctat ggtaatcaca gcaggttcct ccttgtagta tttctgttat tatatgacaa
    19201 aaaagggcgg gtttacaagg gaaatttgaa cggggagaat atttgttcgg ttaattttct
    19261 tgcattggca caggccgtat ggtatgatag gctgagataa aaggagagaa aaaagtgatt
    19321 tcatatatta aaggaactct ggcagagaag atggaaggag cggcggtagt ggaagccgga
    19381 tccatcggat acagaatttt tatgcctgcc tccgctctgg agcttttagg ggcggtgggg
    19441 gatgaagtgg tggtttacat ttattttcag gtgcgcgagg acgctatgag cctgtacggc
    19501 tttctgagcc gccaggacag agagatgttt aagcagctga ttggcgtgaa cggtatcggc
    19561 cctaaggcgg ccctgggact tttaggcacg ttgaggcctg acgatctgcg gcttgccatt
    19621 ctcaccgggg acgccaaggc gatttccagg gcacctggca tcggtgcgaa gacggcgcag
    19681 aggattatcc tggatctgaa ggacaaggtg agcgcacagg agatgctgtc ttcccttgcc
    19741 gttccggcag aggcagccgc cgggcgcgtt tcccaggagg cgtccgcctt cagcgcagag
    19801 gcggccaggg aggctgtgga cgctctggtg gcccttggat attctaatct ggaagcttcc
    19861 cgggcagtga agcaggtgga acttacggag gacatggatg cggaggctgt tctgaaggcc
    19921 tccctgaaat ttctggcgtt tatgtagccg gaaaatgcag ggacaggcag cgcggatcag
    19981 ccgctgccag gaaatcagaa cgtgaaataa gtggagacga aggaagcaga tatgagcaga
    20041 aggattataa caaccgatgt gacggaagag gacaagaaaa tagagaccag cctgagaccg
    20101 cagcttctgg gggagtacat aggccaggag cggatcaagg gcacgctgaa aatctttatc
    20161 gatgccgcca aatccagaaa tgagccgtta gatcacgtgc tgttttacgg gccgccggga
    20221 ctgggaaaga cgacgctctg cggcattatt gccaatgaga tgggcgtcca tatgaaagtg
    20281 acctccggtc cggccattga aaagccggga gagattgccg ctattttaaa cggcctgtcg
    20341 gagggggacg tgctttttgt ggatgagatc caccgcctga accgccaggt ggaggaggtg
    20401 ctctatccgg cgatggagga ctatgccatt gatattatgc tggggaagga ttccagcgcc
    20461 cgctccatcc gtctggagct tccgaagttt acgctggtag gggcgaccac cagggcgggg
    20521 cttttgaccg ctcccctgag agacaggttt ggaatcatcc aaaagatgga tttttatacg
    20581 cctcaggaac tgaaggatat tgtcatgcgg tccgcccagg tgatgcaggt ggccattgag
    20641 gaggagggag ccttcgagat tgccagacga tccaggggaa cgccaaggct tgccaaccgc
    20701 cttttaaagc gggtgcggga tttcgcccag gtgaagtacg acggggtgat tacgaaagcg
    20761 gtggctgatt ttgccctgga tatcctggat gtggataagc tgggcctgga caataacgac
    20821 agggccattt taaacgctct gatccaaaag ttttccggcg gtccggtagg cctggagacg
    20881 ctggcggcct gcctgggaga agacgcggga acgctggagg acgtctatga gccctatctt
    20941 ctgatgaacg gactgattaa caggactccc agaggaagag tcgccacaga ggcagcttac
    21001 cgccatctgg gcatttccat gaatcctgcg ggagacaggc cttagaaaaa cagggaatcc
    21061 aaagaaaatc attgttttta tagaaaattc aggtataatg aagatgacgt tctatgtctg
    21121 aaaacgagaa ggataagaaa acgaaagcgg agaaaaccat ggattccaaa aattatacag
    21181 atgttttaat taacggaaaa atttacacat taggcggcgc ggaggaggag agctacctcc
    21241 agcaggtggc cagctatatc aatgaaaaga tgtccgggct tcagcgccag ccgggtttcc
    21301 agcgtcagag cgatgattat aagtctgtga tgacatgttt aaatctggcg gacgattact
    21361 tcaaggagag acagtatgcg gcccggctgg aaaatgaaaa tcagaacctg gagaaggaaa
    21421 cctacagcct gaagcacgag ctggtgagca cgcagatgaa gctggaggct ctccacaggg
    21481 agacagagga gctgagacgg cagatgaagg agctgatgct tcggattcca gaaagagaag
    21541 aggctccggc ggtgtctgag acggcgcggg aggcagaact ggagcagagc ggggatcaga
    21601 attccttaga aggatagtga aacagcggcg aaaggctgat gtgcgtggcg cgcatcagcc
    21661 ttttaaaagt aaaatgagag ggatggaaat gaacagccag aacagaaaac aggaacagga
    21721 gaaacggtgg caggccgcgg tgaaaagagg cgcggagatt ttggcgccag ccggatcctt
    21781 tgagagcatg aaggcggctg tggcggctgg agcggacgcc gtctatatcg gcgggaataa
    21841 attcggcgcc agggcctatg cagacaatct ggacgaggac aggatgaagg aggccattga
    21901 ttatgcccac ctccacggct gcagaattta tatgacagtg aataccctgg taaaggagcg
    21961 ggagatgaag gagctttaca gctatctgct cccttactac gagcaggggc tggacgcggt
    22021 gattgtccag gatatgggag tcttttcttt tgtaaaacgt cattttccgg atctggacgt
    22081 tcacgccagc acccagatga cggtgacggg agcgccggga gcggccctga tcggcagaat
    22141 gggggcgtcc aggattgtga cggccagaga gctttctctg gaggagatag aggagatata
    22201 cagggagaca ggggctgaga ttgaaagctt tgtccacgga gcgctctgtt actgctattc
    22261 cggccaatgt ctgttcagca gcctcatcgg aggcagaagc ggaaacaggg gccggtgcgc
    22321 ccagacctgc cgcctgccgt tttctgtcag aagagggaag gagcttctga acggaaaaaa
    22381 cgaaaaatat gtgctgagcc tcaaggacct gtgcagtctt gacattctgc cggatattct
    22441 ggaggctggg gtattttcgc tgaaaatcga gggcagaatg aaaagtcccc gctacacggc
    22501 aggcgtggtg tccatttaca gaaaatatgt ggatcagtac atgaaatatg gacgaaaggg
    22561 atatcaggtg gatccggcag atcgaaagac actgcttgac ctgtttgacc ggggaggcca
    22621 gacggagggc tattacaggg agcacaatgg cagagatatg gtggttctga aggaaaagcc
    22681 ggcctttcgg gaggaaaacc ggccgctgta cgattatctg gataaaacct atgtaaacgc
    22741 atctctccag gaaccggttc tgggatgggc cagagctgca gagggagagg aactgaggct
    22801 gaagctccag acggacagtt ttggaagcac catagaggcg gaggtttccg gcggtcctgt
    22861 ccagacggca aaaaatcagc ccatggcggc ggagcgcata gaaaagcagc tgaataagac
    22921 gggaaatacg ccgttttatt ttcagtccct gcaggtggag acagagggaa actgcttcat
    22981 tccggtgcag gagctgaacg aactgagaag aaacgccttt gaaaagctgg aaacgcagat
    23041 tctaagccaa ttcagaagac aggaaccgtc tggacatgag aacggcgaag gagacgggaa
    23101 aaaggcgcag gagggaaaac ttcagaagag ggaaatttcg gagaacggca cagaaggaga
    23161 gaagaagggc agagaacagg cggttcttca cgtatcgctg gaggagccgg aaggacttga
    23221 aacggttctc tcgttccggc aggcggccgt tatttccatc gacgcggccg gatttccggc
    23281 tgagagctgg aagcagacgg ttttaaactg ccatgagagg ggaaaggagt gccttctttt
    23341 gctgccgcac atttacaggg cggaggcaaa gcggtatttt gacgcccatc tgagggagct
    23401 ttccgaggcc ggctttgacg gggctgtaat ccgggcctgg gaggaagcgg aactgattgc
    23461 cagatggaga cgggaaggcg tgtttttccc gaaaatcaca gtctttgatc atggactgta
    23521 cagctttaac agcctctcgg aagagtggat ggagcagatg cttccaggag agacgatccg
    23581 gtttacagcg cctcttgaat taaacagcag agagctggag gagaagggaa tccgcgggga
    23641 agagctgatg gtctatggaa atattcctat gatggtgacg gctcagtgtc tgaaaaagac
    23701 gctggaaggc tgtacgggaa ggccggagct tctgtggatg aaggatcgga agggcaagga
    23761 gttcccggtg aagaatcact gccggttctg ctacaatacg atttataatt ccagtcctct
    23821 gtctcttctg gcagacagaa gcctcattga gagactgggg ccgtctgttc tcaggctttc
    23881 ctttaccacc gaacagccgg agcggatccg ggaggtattg aaggcctttt cagaggaatt
    23941 tatctccgga acagagaaag gcggggcgcc ggaactgtca ggcgagttta caagaggcca
    24001 ttttaagcgc ggagcggagt aggtgagaca ttatggcgaa tctgattacg aacgtatcca
    24061 agtatctgat gatactttta attgcgattt acacctatta caatttccgg tttttcggaa
    24121 tcagggacga gtgggggaaa cggcgtctgt gccgtctcca gaatgtggtg atggtgttaa
    24181 tccacactct tgcgtacctt attatttacc tgcgcacaga ggatgagaag acgctgatgt
    24241 tttttggagc gcagcttttg tttttctttc tgtatatggg actgtaccgg ctgttttaca
    24301 ggaatctgtc cagacttctt ttaaacaatg cctgtatgct tctgtctacc agctttatta
    24361 ttctgaccag gatttccatg gaccgggcgg taaggcagtt tgccattgtg gcggtggctg
    24421 ccgccgttac catgatcatc ccgtttatta tggaccgggc gtggcagctg tccaagattc
    24481 cgtgggttta cggaagcatc ggcctggctc tgcttttagt agtgtgcgtc atgggaaata
    24541 cggcttttgg agcgcagctt tctatcaata tcggaggctt ctcctttcag ccgtcagagt
    24601 ttgtaaagat cagctttgta ttttttgtgg ccactatgtt ttaccgatcg gtggatttta
    24661 aaaccatagc cgtcaccact gccgtggccg cggcccatgt gctggtgctg gtgatgtcca
    24721 aggatctggg aagcgcgctg attttctttg tcacctatct gctgatgctg tttgtggcga
    24781 cgggaagctg gctctacctg ggactgggag ccggcagcgg agcggcggcg gctgtgattg
    24841 cctacagcct gttttcccat gtgcgtacca gggtggaggc atggctggat ccctggagcg
    24901 atatttcggg aaagggatat cagatcagcc agtccctgtt cgccattgga acgggaggat
    24961 ggtttggcat ggggctttat caggggatgc cgtctaaaat tccggtggtg gaaaaggact
    25021 ttgtcttttc agccatttcg gaagaaatgg gaggcatcta cgccatctgc ctgattctca
    25081 tctgcctggg ctgctttatg cagtttatga tgattgccgc caaaatgcag gctgtctttt
    25141 ataagctgat tgcctttggg ctgggaacca catacattgt gcaggtattt ctgaccattg
    25201 gcggagtgac gaaatttatt ccctccacag gagtgacgct gccgtttgtc agctacggcg
    25261 gaagctccat tctcagcacc tttattgtgt ttaacgtggt tcagggactg tatattttaa
    25321 aacgcaatga agaggaggaa gattatgatg aagaagaatg atccgagtcc tgaaaaacac
    25381 gggaaagctt ctgcttcccg ttccagaaaa cgctctgaag ccgcaaagga gcaggagctt
    25441 agggaggctg ccagagagaa ggcagataaa aatattctgc ggattaccta tgcctttgcg
    25501 gctttgttca tcggcatgtg cctgtatctg ggctggtttc ttcaggtgga cagtgaaact
    25561 gtcatcaaca gctcctacaa tgccaggctg gaccgcttct ctgaccggat tgtaagagga
    25621 aagattttga gcagcgatgg aaaggtactg gcggagaccc aagtggcgga ggacggaaca
    25681 gagaagcggt attacccata caattacctc tacgttcatt cggttggcta ttctggaaaa
    25741 aacggaaaga caggcatcga gtctctggca aacttctatc tgctgtcctc ccatgtcaat
    25801 ctggtggaga agacggtcaa tgaactgcag ggaaagaaaa atatcggaga caacgtggtg
    25861 acgactctgg attccgatct gcagcagaca gcttccgacg ccatgggaaa caggagaggg
    25921 gctgtgattg ccatggaacc tgatacggga aagattctga ccatggtatc ccagccgaac
    25981 ttcaatgcca atacagtgga cgagcagtgg gcggagctga cttcaccgga gaacaccaag
    26041 gcgcagctgg taaaccgcgc gacccaggga ctttactccc caggctctac ctttaagatt
    26101 gtgacggctc tggagtatct tcatgaaaat ccagacggca tgagccagtt tcattttgac
    26161 tgcgacggcc tgatggagca gggagagtat caaatccgct gctaccacgg ggaatcccat
    26221 ggcagccagg atctgcggat gtcctttgcc aattcctgca acggagcttt ttcgactatg
    26281 gggctggggc tgaatctgac gcagtttaac agtcttgcca gccagctttt gtttaacagc
    26341 agtctgcccc tttctcttcc ctacaaggaa agctcttttg tcatgggaga gggggctgac
    26401 gagtgggaac ggcttcagac ctccatcggt cagggaaaga cgcagattac tcctatgcac
    26461 aacctgatga tcacagcggc ggttgccaac gggggcactc tgatgaagcc gtatatgatt
    26521 gatcatgtgg aaaacgctgg gggccagacg gtaaagaagt ttcttccgga ggcttacggc
    26581 acgctgatga gctctgagga cgcctctgtt ctcagcggcc tgatgacggc agtcgttaca
    26641 gacggaacag gatccgcgct tcggggcgct ccctatacgg cggcgggaaa gacgggatct
    26701 gctgaatttg agacaggaaa agagacgcat gcctggtttg tgggctacgc gcctgtggag
    26761 gacccgaaaa tcgcagtctg cgtgctcctg gaggagagtg ggtcaggcgg aaagcaggcg
    26821 ggacctgtgg ccagagccgt tatggacaaa tattttgaga aaaatcctct gcagtagcgg
    26881 ggacggatag gagagacgga tgacacaact tcagatgata ctgtttttat gccccatatt
    26941 cttttttacc agttttgtag acgcagtttc aggcggcgga ggactggtgg ccctgccggc
    27001 ctacctgttt acagggatgc cggtacacag cgcctatgcc tgcaataaag tgggatgcgt
    27061 ggtgggaagc tttacttcct ttatccgctt ttggaaaaat gggctgatcg atatgaaaac
    27121 ggctcttttt gtgggagcgg tcaccttcgc gtgctccacc tgcggagcgc agattgtgct
    27181 gcacctgccg gaccggcctc ttaagattat gattttagcc tccatgccgg ctgtggcggc
    27241 cctgattttc ttccagaaaa attatcctga ggtaaacaga acctcagaga tcacaggctg
    27301 gaagcgagga gggctctgcc tgctgtcagg agttatgatg ggactttatg acggaatttt
    27361 agggcctggc tccggaaccg ttgtgatgat tctctttacc aagctgttaa aatacaattt
    27421 aattactgca tcgggaaata cgaaggtcat tctgctggcc tccactctgg ccgcctcggt
    27481 gtcctatatc ctggcgggaa aggtgatctg gaccgtggca gttcctgtgt ctgtcttcgg
    27541 aatgctggga ggatatgtgg gcgccggaat ggccatcaaa aaaggcacaa aatttatccg
    27601 ccccatgatg cttggcatcg cggccctcct ggtgatcaaa atggcggtgg atctggctgc
    27661 cggagggcag tagggatacc gcggccggat tttcctctcc gtcttgcaca ttgtcccaaa
    27721 aagcagtata ctaaacagta ataacaacgc caggagggat tgcgatgatt gaggcaacga
    27781 gctgcggcgg tgtggttatt tttcgaggta aaattcttgt tttgtataag aattataaga
    27841 acaagtatga aggatgggtt ttgccgaagg gaactgtaga gcctggggaa gagttcaagg
    27901 aaactgccct cagggaggtc aaggaagaga caggcgtcac tgcgtcgatt atcaagtata
    27961 tcggcaagag ccagtacacg ttcaacactc cgcaggatat ggtggagaag gacgtctact
    28021 ggtatctgat gatggcggac agctattaca gtaaaccaca gcgggaagag tattttgtgg
    28081 attcaggtta ttataagttt tatgaggctt atcatctgct taagttttcc aatgaaaagc
    28141 agattctgga aaaggcttat aatgaatacc tggatttgaa gaggagtaat ctttgggggt
    28201 caaaaaagta cttttaagag caacggacag agggctgaaa cacacgggac agacgtgtgc
    28261 ttcagccttt tctgatccgg agggaaattt cgttttgatt gaaaaatctg gctaattata
    28321 ttaaaatggc atataatacc gcttaggtcc tcggcgggat ctgctgaggg caggaggaga
    28381 gaaaaggaga ataggatcat gaaccagtca tttgaaaaat tacagaatca gctggaaaag
    28441 gctatggccc ttcagacggc tatggtgctg tttgagtggg ataatgagac tgcggcgccg
    28501 aaggaggcgg cagagagaac ggcggtggtc atcggttctc tttccagcca gtatcttgat
    28561 attatgacag gagagaagct gaaaactgcc ttggaagagt gcagtggaca gatgtccgaa
    28621 atgacggaag tggagcaggc catcgtcaga gagacaaagg aagaggtgga aaagctggag
    28681 cgcattccgg ccgacgagta ccgcagcttt gcagagctga cagccagggc caccggcatc
    28741 tgggcggacg ccagggagaa gaaggatttt tctctgttcg cgccggtttt aaaggaaatt
    28801 gtggattatc agaagcggtt tgcttcctac caggccaaag agggacagaa gctttacgac
    28861 gtgatgctgg acaattatga gaaggatttt ggcatgaagg agctggacga gttcttccgc
    28921 gttgtgaaag agggaatcgt gtcgctttta aaggagtctg caaagcgctc ggagcagatc
    28981 gacgacagct ttttaagcgc cggatataca gaggagcagc aggaaaaggc ggctcgtttc
    29041 ctggcggaat atgtgggctt tgactttgac aggggaattc tggctgtcag cgcgcatccg
    29101 tttaccacga acctgcacaa taaagatgtg agaattacca cccactacct ggatcggatt
    29161 gactcttcca tctattcagt gatccacgag tcgggccatg cagtttatga gctgggaatc
    29221 agggatgatt tgactcagac gccggccggg cagggggcgt ccatgggaat gcatgaatcc
    29281 cagtccagat ttttcgagaa tattatggga cggaacagaa atttctgggt tcccatttat
    29341 ggaaacatgc aggagatatt cggcagtcct ttaaaggaag tgagcctgga cgattttctg
    29401 gcggcagtga acaagacgat tccgggactg atccggacgg aggcggacga gctttcctac
    29461 tgcctgcacg tgctggtgcg gtatgagata gaaaagctga tgatcgagga aaatgctgag
    29521 attgacagtc ttccagagct gtggaacgac aagtatgagg agtatctggg aatccgcccg
    29581 aagaatgacg gagaaggcat tttacaggat attcactggt ctcagggttc cttcggctac
    29641 ttcccatcct acgctctggg caacgccttc ggcgcccagc tttatcacaa aatgaagcag
    29701 gagatggatt ttgacgggct tctcagagag ggaagagcag acgcaatcag agaatatctc
    29761 cgggagcaca ttcatcagta cggaaagctt aagaccagcc gccagctgtt aaaggatgcc
    29821 acaggcgaag actttaatcc ggcttattat gtagaatatt taacagaacg gtacggaaag
    29881 tagacgcgct ggagaaatta aaaaaaacgg catttctatg tcaggaatgc cggttttttc
    29941 ggaaatgctc cattctcgac aggtggaaat tgatttccgc ccccatgaag agaatacaga
    30001 tgcagaagta cagccacagc atcagcacgg ctacgctggc aagacttccg tacatggtag
    30061 agaatcttga aaagtattta aagtaaagag agaaggcgaa ggagaacaga atccagcata
    30121 ccgtagagaa cacagctccc gggagctggc ttttcagcct catcttctcg taggggagaa
    30181 aggtataaag gcctgtgaaa aacacggcca gaataatcag agacagaatg gatcgcagac
    30241 tgatcaggta aggagacaga aagcggagaa agggcagaaa ccggagcgcc agattctgga
    30301 gaaccgttcc aaagaccaga agagccaggg acatgacgca gacagccatg aatacgatgg
    30361 tgtagccaga gttaatcaga cggctgatta catagcctct ccgcttcgga cagccgatga
    30421 tccggttcag cccccgctca atgccctgca ttcccctggc ggctgaccac agggtgacga
    30481 tggaggatac ggagagcagg gcggcggagg atttgaagta aatttcgccg ataatggtgt
    30541 acaccagagg ctgtacttct atggggagca gccgggacag cagatagagc agatccnnnn
    30601 nnnnnnactg aagcactgtg aggagaagaa tgataaacgg cacggaggag agcacaataa
    30661 aaaaggatgc ctgagcggca tacaccgtga tctcatccct tacgaattta tcatatatct
    30721 gtttgcagtg taccagaaaa tagatcatac atttctccat ttgtttcgat tctattaaca
    30781 tattatcacg ggggaggaaa aataacaact tttcttgaaa attaagagga ttacaatgaa
    30841 aaagctactg aactatctaa gcgcttataa aaaggaagcg gtgctggcgc ctctttttaa
    30901 gatgctggag gccagctttg agctgctggt ccctcttgtc atggcccaaa tcatcgacac
    30961 gggaatcaaa aaccaggatt tggcttacat tttaaaaatg ggagctgttt tagtgcttct
    31021 gggagtgata ggtcttgcct gctccctgac cgcccagtat tttgcggcca gggcggcagt
    31081 gggattcgga gcgggagtga gacgggatct gttccgccat attaaccgcc tgtcctattc
    31141 ggaaatcgac gcccagggaa cggcgacgct gattaccaga atgaccagcg acgtcaacca
    31201 ggtgcagtcg ggagtcaatc tgacgctccg cctgttcctg cgctctccgt ttatcgtatt
    31261 cggggccatg attatggcct ttaccattga tgtgaaatca gcgcttattt tcgcggcggc
    31321 gattcccctg ctctccttgg tagtgttcgg cattatgctg atcagcatgc ctctctacaa
    31381 gcgagtgcag agacagctgg actgggtaat gcagattacc agggaaaacc tgacgggagc
    31441 cagggtgata cgggccttta acagagagca ggacgagatt gcctccttta aagaggaggg
    31501 aggactttta atccgcttcc agattttcgt gggacggatt tccgctcttt taaatccagt
    31561 tacctatgtg attgtcaacc tggcgattgt ggttctgatt tacacgggag cgggacaggt
    31621 ggacagcgga cggatcccgc agggagaggt ggtggccctt gtcaactaca tgtcccagat
    31681 tctggtggag ttgattaagc tggccaattt gattatttct attaccaaag cgctggcctg
    31741 cgcgggacgc atcagcatcg tgttcgagat ggagagcagt attgcggatc cgggagaaga
    31801 aaagggcagg caggtgaagg aaggtgagaa tccctctgtt tccggaacgc ccagggtttc
    31861 cttccagaac gtcagcttct cctaccaggg atccaaagaa gagtctctct ctgacatcag
    31921 ttttgatgct gcgcctggag agatcatcgg cgtgattgga ggaaccggat ctggaaaatc
    31981 cactctggtg aacctgattc cgcggtttta cgatgtgaca aaggggcagg ttctggtcaa
    32041 tggaaccgat gtgagagctc agtccctctc gaaactgagg ggacagatag gagtggttcc
    32101 ccagaaggcc gttctcttta agggaaccat ccgcgacaat atgcgctggg gaaaggagga
    32161 cgcctctgac cgggagatag aggaagcgct ggaaacagca caggccctgg aggtggtgaa
    32221 atccagggaa aacggtctgg acgccatgat tttccaggga gggaaaaacc tgtccggagg
    32281 acagagacag agacttacca ttgccagagc tctggtgagg aagccgcaga ttttaattct
    32341 ggacgacagc tcgtcggctc ttgattttgc cacagacgcc agactgagga aggccctgag
    32401 ggagcgcaca gggggcgctg ctattttcct ggtatctcag agagcctcgg ctctgcgcca
    32461 cgcagatcag attctggtgc tggacgatgg aaggctggca ggaaagggaa agcatgagga
    32521 attattggag acctgccctg tgtacaggga aatctgcctg tcccagcttt caggagagga
    32581 ggcggagcag tgatggcaaa aacagagatg aaaaaagaca gggaagcgaa agggattttt
    32641 aaggatacgg caaagtcaga caccataaaa agggtgctga agcatatcgg agcttacagg
    32701 tggctggtgc tgctttccct ggcgctgtct gcagtgacag tggccctgac tctctacatt
    32761 cccattttaa tcgggcaggc ggtggatctg attacagggg aagggcaggt agactttgac
    32821 ggcctgttcc ggatctttgg aatcatggcg gcggtgattc tggttacggc ggcggcccag
    32881 tggctgatga acgccatcaa caatcacatc acctaccggg tggctatgga cgtccgggag
    32941 aaggccttct gccatttgga aattctgcct cttaaatata tagacggcca ttcctacggc
    33001 gacgttttaa gccgtgttat cacagatgtg gatcagtttt ccgacggtct tttgatgggc
    33061 tttacccagc tgttttccgg aatactcacg attttcggga ccctggtatt tatgttttcc
    33121 gttaatccct ttatcgctct ggtggtggtt ctgatgacgc ctctttccct gctggcggca
    33181 ggctatattg ccaaaaagac cttctccatg tttcaggagc agtcggaggc cagaggagag
    33241 atgacttcct taattaatga gattgtggaa aatgagaagg tggtgcaggc cttctcctat
    33301 gagcagaagg cggaggagcg gtttgataaa attaacagcc gcctggaaag ctgcagtctt
    33361 cgggctacct tcttttcttc tattacaaat ccggccacac ggtttgtaaa cggcctggtg
    33421 tacgcaagcg tgggaatcgc aggggcagct gcggctatcc atggtctttt gagcgtggga
    33481 cagctgactt ctttcttaaa ctatgcaaac cagtatacaa agccgtttaa tgagatttcc
    33541 ggggtggcca cggagcttca gaacgccgtc gcctcggctg ccagagtgtt tgccctcatt
    33601 gacgaggaac cgcagacgcc ggaggcagaa caggcgatag agcttcagga ggcggacgga
    33661 agagtggagc tgtctcacgt agcgttttcc taccagccgg acacgtctct gattgaagac
    33721 ttaaatctca cggtggaacc ggggaaaaag atagccattg caggccctac cggatgcgga
    33781 aaaagtacgg tgatcaatct gctgatgcgt ttttatgatg cggacagcgg atggattcag
    33841 gtcagcggct gcgacatcag gcagatgacc agaaaaagtc tgcgggcttc ctacggaatg
    33901 gttctccagg agacgtggct gaaagcggcg tctatccggg ataatattgc ctatggaagg
    33961 cctgacgcct ccatggagga gattgtggaa gcggcgaaaa aagcccatgc ccacagcttc
    34021 attaccagaa tgccggaggg atacgacacg gtgatttctg aggacggagg cagtctttcc
    34081 cagggacaga agcagctttt gtgcattgcc agagtgatgc tctgccagcc tcctatgctg
    34141 attctggatg aggctacctc gtctattgat acgagaaccg agctgatggt tcaggaggcc
    34201 tttgaccgga tgatggaggg gcgcaccagt tttattgtgg cccaccgcct ttctaccata
    34261 cgaaaggcag accagattct ggtaatgaag gagggaaaaa tcatcgagca gggaaatcat
    34321 gaagagctgc tggcgaaagg aggattttat tgtgaactgt acaacagcca gttcgccgtc
    34381 tcataaggaa gcggccgtga ttaaaagaga aacggatcgg caggagacgc ggggacagga
    34441 aaaattgaga atcctggtaa gcgcctgcct gctgggagaa aactgcaaat acagcggagg
    34501 atccaaccgg gacgaaacgg tgctgatgtg gaaaacgaag ctggaacagg aggaaaaggc
    34561 agagtttatc cccatctgcc cagaagtggc aggaggcctt cccacgccca gaatgccggc
    34621 agaaatcaga ggagagagag tcgtaacccg cgacggcagg gatgtgactg cagaatatga
    34681 agccggggcc gaagaggctc tcgcgctgtc agggaagcac ggctgcagat atgcagtcct
    34741 gaaggagaga agcccttcct gcggaagcgg aaccgtctat gatggaagct tttcagggac
    34801 tttgacagcc ggagacggaa tcgctgccgc tcttttaaag aaaaacggcg taatggtagt
    34861 tggagaaagc caggcgcaga agctgtttga aatcttgtaa atcagccagg cagacaggtt
    34921 ctggattata tttttaacag aaaattccaa tttttggcaa aaatgccgct gtccatgtaa
    34981 tttttttgtt tctttactaa aaggatgata cgtcgtccta gttgctcacg aatattgtat
    35041 aaactaaggc cagaataaaa aaggaggctg aatttatgca gatttgtgaa gcaactgtaa
    35101 agagaataga ggagcttcga aagcgagaac ggcttaccct gtacgctctg gcctacaaaa
    35161 cggggatgcc gccctccact ttaaaatgta ttatgaacgg aagaagcaaa aatccgggga
    35221 ttgtcaatat taaaaagatt gccgagggct ttaacatgac aatccgggaa ttttacaaca
    35281 gcgagatttt tgacgattta gagcaggagg actaggaaga gagaagtttt ccatgctctg
    35341 ataaaagaag gcggagaaag aaaaaatagg agaggattct gagtatggaa aagaaatcga
    35401 gagatcagtt ccggaccagg ctgggattta tcgtggcctg catcggttct gctgtgggga
    35461 tgggaaatat atggatgttt ccctatcgga cgggagcgtt cggaggagcg gccttcctga
    35521 tcccctactt tatttttgtt attctgctgg gattttccgg cgtgctggga gagatggcct
    35581 ttggccgcgt gatgcgtacc gggccgacag gggcctttgg aaaggccatg gaaatgagag
    35641 gaaagagggg aggacgcctg atcggcctga tccctgtcat cggttccctg ggaattgcca
    35701 tcggttattc cgtagtagtg ggctggtttt taaaatatct gtctgcggca gtttccggaa
    35761 cgctggggca ggtggaggat atgggagctt attttgcctc cctgtcaggc agctttggaa
    35821 gcgtaggctg gcatatgctg ggcctggccc tgaccttcct tatcatgctg ttcggcgtat
    35881 ccggcggaat cgaaaagatg aataagatca tgatgccttt gtttttcgta ttctttctca
    35941 tccttctttt ccgcgtggcg tctcttcccg gagcagtgga aggctataaa tatctgttta
    36001 tccccagatg ggagctgctt ggcaatgtaa agacctgggt ttacgccctg ggacaggcct
    36061 ttttctccct gtctctggcc ggatcgggca ccattgtcta cggcagctat ttaagcgacg
    36121 acgcggatgt ggtgacctgc gccagaaacg tcgctttttt cgacacctgc gccgcgcttc
    36181 tggcgggaat ggtggtgatt ccggctgtct ttgcctttgg gctggacgtg acggcgggac
    36241 cgcctctcat gtttatcacc cttccggctg tctttaacca gatgccggcc ggctggctgt
    36301 tcgcagtcat tttctttatc gccgtgctgt ttgcagcgat tacctccctg atgaatctgt
    36361 tcgaaacgcc gatcgaggcc cttcaggagc agtttcagat gtcgagaaaa gcggcggtgg
    36421 cctgcgtggc gtttattgcg gcggcagtgg gcgtgtttat tgagagcgcg gacgcagtga
    36481 gcatgtggat ggacgcagtt tcgatttaca tgatccctct gggagccctg ttggcggcag
    36541 tcatgttttt ctgggtatgt ccgaaaggct tcgccagaga gcaggtgcag aagggcagag
    36601 aaaaaatgct tggttcctgg tttgaaccgg tgacgcggta tttattcgta gggctgactc
    36661 tgggcgtgta cgtgctgggc attctgtttg gaggaatcgg ctgatctttc agaaaagtct
    36721 tgaaaagata aaaaagatga tgtataataa tgcacatctt acaggggaag gggagtgagc
    36781 attatcactt cctttttgtc attttagtaa ggaaacttta ttttagttta ccggagagga
    36841 gaaagagatg agcattagaa ttggtattct cggatatgga aatttaggac ggggcgtaga
    36901 gtgcgcggta aagcagaatc ctgacatgga gctgaaggca gtttttacga ggcgcgaccc
    36961 tgagacagta aaaattctca cagagaacgc gaaggtatac cgggcagagg aggcagaacg
    37021 cttaaaagac gagatcgacg tgctcattct ctgcggagga agcgcaacgg atctgccggt
    37081 gcagactcct gcttttgcca gatggtttaa cgtagtggac agttttgaca cccacgccaa
    37141 tattcctcag cacttcgagg cagtggatca ggcggcttct gagagcggcc atgtgggcat
    37201 catttccgta ggctgggatc cgggcatgtt ttccttaaac cgtctgtacg ccacggcagt
    37261 tcttccagag ggaagcaatt acaccttctg gggtaagggc gtaagccagg gccactcaga
    37321 tgccatccgc cggattgcag gcgtaaagga cgccagacag tacaccattc ccgtagagag
    37381 cgcccttgag tctgtgagaa acggggagaa tcctgagctg accaccagac agaaacacac
    37441 aagagagtgt tttgtagtgg cagaggaggg agccgatctg gctgccattg agcaggaaat
    37501 caagaccatg aagaattatt tcgacgagta cgacacgacg gtacacttca tcagccagga
    37561 ggaactggac agagaccaca agggacttcc acacggcgga ttcgtattca gaagcggcag
    37621 aaccggctgg gaaaaagaga acagccatgt gattgagtac agcttaaagc tggattccaa
    37681 tccggaattt acttcttctg tcattgtggc ctacgcaaga gctgcttaca agatgagcaa
    37741 agagggacag aagggctgca aaacagtctt tgacgtagct ccgtcctatt tatctccaga
    37801 gagcccggct gacttgagaa agaaatatct gtaagcggcg gcttcaggga gagaatttat
    37861 gaaacgaaag aaatggaaga tacacgcaaa acagacggcg gctctcgcca tggccttcac
    37921 cctgatgatt tcaggcgcag cttcagcggc gcccattcct ccggatggat ccgggacagg
    37981 gcagaccgct caggggggaa accagacgtc tcaaggcggc ggacagaatg gacagcaggc
    38041 cacaggaccg gcagggccgg gaaacggcgc tggaaactca ggctctgcct ccaggctgcc
    38101 gtctctttcg ggaaccgtgt ccacatccca gagcagccag acgtcccaga acagcgcgca
    38161 gacaggaagc cagggaagca gccaggcggc agttccccag atcaaggcgg agggcgcagt
    38221 tttgtatgac gccacccggg atcaggcgct ttacgagaaa aatgcggata cccgctatta
    38281 tccggccagc attacgaaga ttatgacagc gcttctggtg ctggaacact gcaatttaaa
    38341 cgatacggtg acgttttccc agacagcggt tacgaatctg gagtcaggag ccgtgaccct
    38401 gggcgttcag gcaggcgatc agtttacagt ggagcagtgc ctgtacggcc ttctcttaaa
    38461 gtcagccaac gagattgcca acggtctggc agagcacgtg tcgggaagca tcagcggatt
    38521 cgccgatctg atgaatcaga aggcggcttc tctgggctgc accaacaccc attttgtcaa
    38581 tccaaacggc ctgaacgatt ccaaccacta tacgacagcc agagatatgg ctctcattgc
    38641 agacgcggcc ttttccaatc ccaccctctg caaaatagcg tccacagtca attatgactt
    38701 tcctgccacg gccagcgttc cgtctgtgcg gaagctgacc atggggcaca agatggtcaa
    38761 tccagcgaac agcgagtatt acagcggtat tgtaggcgga aagacaggct atacctcttt
    38821 ggcgggcaat acccttgtca cttgcgcgga gagaaacggc acaaggctgg tggccgttat
    38881 cttaaagagc cggcagacgc actatgcaga caccagagcc ctgttggact acggcttctc
    38941 actggttcag tccggcggat ctggatcggg aacaggcggc cccggcggcg gtccgggaag
    39001 ccagcaggga ccgggaggcg gctctgcatc ctccaatccc cactgggtgg aggattccag
    39061 gggatggcgt tttgtcaagg ccgacggctc ctacgctgcc aacgaatgca tggagattaa
    39121 cggggagatc tactgcttta agccggattc ctatatcgtg agcaatgact ggtatcagat
    39181 aggaggaatc tggtatttct tccgtccaag cggcggcctg gcgaaaagcc gctggatcga
    39241 gacaggcgga aagtggtact acgtagacgg aaacggatcc ctgttcacaa acggaaccac
    39301 gccagacggc taccgggtag acgcagacgg agtgtggatt cagtaactgc cctttgtcta
    39361 tgtccaggaa aaaattttca gtgactttaa atggaacaag aaaatttttc cttgtccccc
    39421 gtcctctgct tgacaatctc cgtcaaacct actatattat ttatagctgt ctggaagagg
    39481 ttatgttcag acagacacag cgctgtccac agaggcagca gaaatgaaac agaaaaaggc
    39541 tgagaaaaag aggagtaggc aggaagccgc ccgccagaga gagcagtcag ctggctgaga
    39601 gactgcttgg ggaaaggtct gctgaaggta gcttttgagc ccggcccttg aacctgattt
    39661 ttgcggttga gaagatcaga cagtagagga ctgcgggggt tcccgttaca ggacagatga
    39721 gattgccgtt ttatacttgt gcggcagaat aaaggtggta ccgcggtgat tcgccctttg
    39781 catattgcta tgcagagggc ttttttattt cataggaaaa aataggaaaa aacattctat
    39841 gaaataaaaa atgctccgca ggaattccgc tgcgggagat gtttgggaaa ggagccagaa
    39901 tgtccgttca ttcaggaaaa aagagccagg cctccagctg cgagacctgc agcaattacg
    39961 tctatgacga agactatgga tactatgtct gcgaggccag ccttgacgag gacgagatgg
    40021 cggcctttct gggagaccgg aaattccagt gtccctacta ccacataaac gacgagtatc
    40081 tgattgtgcg taagcagatg tagaatcgaa cacgcgcaga aacaataaga aaaaggagat
    40141 tacaggatga aagaactgga gaagaactac aatccggcgg acattgaagc ccgcctgtac
    40201 cagaagtggc tggacagcaa gtatttccac gcagacgcag agcgcggcag aagagaggga
    40261 aagaagccgt tcaccattgt aatgccgccg ccgaacatta caggacagct ccacatgggc
    40321 cacgctctgg acaataccat gcaggatatt ttaatccgtt acaagagaat gcagggctat
    40381 gaggctctct ggcagccggg aaccgaccat gcggccattg ccacagaggt aaaggttatc
    40441 gacaagttaa agagccaggg cattgacaag cacgacctgg gccgcgaggg cttcttagag
    40501 aaggcctggg agtggaagga agagtacgga agcagaatcg taaatcagct gcacaagctg
    40561 ggatcctctg ccgactggga cagagagcgc ttcaccatgg acgagggctg ctccgacgca
    40621 gtgcttgagg tatttacaaa gctctacgag aagggatata tttacaaggg atcccgcatt
    40681 atcaattggt gtcctgtatg ccagacctct atttctgacg ctgaagtaga gcacgaggag
    40741 caggacggct tcttctggca catcaattat ccgattgttg gggaagaagg acgctttgta
    40801 gagattgcca ccacccgtcc tgagacgctt ctgggagata cggcagtggc tgtaaatcct
    40861 gaggacgaga gatacaagga tttagtggga aaaatgttaa agctgcctct cacagacagg
    40921 gagattcctg ttgtggcaga cgagtatgta gataaagagt ttggaaccgg ctgcgtaaag
    40981 attacaccgg cccacgatcc taacgacttt gaggtaggaa aacgccataa tctgccggaa
    41041 atctgcatta tgaacgacga cgctaccatc agcgctccgg gaaaatactt tggtatggat
    41101 cgctatgaag ccagaaaggc tatggtagag gatttacagg agcaggggct tttagtaaag
    41161 gtagttcccc attctcataa tgtaggaacc catgaccgct gcggtacaac cgtagagcct
    41221 atggtaaagc ctcagtggtt tgtaagaatg gatgagatgg caaagccggc agtggaggcc
    41281 atcaagtcag gaaggctgaa attcgttccg gagagctttg gaaagacata tcttcactgg
    41341 ctggagggca tccgcgactg gtgtatttcc agacagctgt ggtggggaca cagaatcccg
    41401 gcctactact gcgatgagtg cggcgagatg gtggttgcca agaccatgcc ggagaagtgc
    41461 ccgaagtgtg gctgcgtcca catgacccag gacgaggata ctttggatac ctggttctcc
    41521 tccgccctgt ggccgttctc cacgctggga tggccgaaga gcacgccgga gtacgagtat
    41581 ttctacccga cagacgtgct ggtaacaggc tacgatatta tcttcttctg ggtaatcaga
    41641 atggtattct ccggtctgga gcagactgga aaggagccgt ttaacactgt tctgatccac
    41701 ggccttgtca gagactccca gggacgcaag atgagcaagt ccttaggaaa cggcatcgat
    41761 ccgctggagg tgatcgacaa gtacggcgca gacgccctga gaatgacttt gatgacagga
    41821 aatgctcctg gaaacgatat gcgcttctat tgggagagag tggaggccag cagaaacttc
    41881 gcaaacaagg tatggaacgc ttcccgcttt attatgatga atgtggagaa ggcgccggaa
    41941 agccaggcag ctctgtctga tctgactatg gcggatcgct ggatcctctc caaggtaaac
    42001 actctggcca aggacgtgac agagaatatg gacaagtacg agctgggaat tgctcttcag
    42061 aaggtttacg actttatctg ggaggagttc tgcgactggt acatcgagat ggtgaagccg
    42121 cgtctctaca gcgacgagga taccaccaag gcagccgcta tctggacctt aaagacagtg
    42181 ctcatccagt ccttaaagct cctgcatccg tatatgccgt ttatcacaga ggagatcttc
    42241 tgcaatctcc aggaggagga accgtctatt atgatttcct cctggccggt ttataaagag
    42301 gagtggaatt ttgcttccga ggagaacgca gtggagacta tcaaggaggc agtgcgcgga
    42361 atcagaaacg tccgcacatc catgaacgtg ccgcccagca agaaggcaaa ggtttacgta
    42421 gtttccgagg acgagtccct gcttggcatt tttgagcaca gcaaggtatt ttttgctacc
    42481 ctcggatacg ccagtgaggt atgcctccag aaggacaaga caggaattgc cgacgacgcc
    42541 gtgtctgccg taatcccgaa ggcagctatc tacatgccgt ttgcagagct ggtagacatt
    42601 gacaaggaaa tcgagagact gcagaaggaa gaagagcgcc tgaccaagga gctggcccgc
    42661 gtcaatggca tgcttggaaa tgagaagttt gtaagccgcg cgcctgaggc taagattgct
    42721 gaggagaagg caaagcttga aaagtatact cagatgatgg accaggtaaa agagcgcctg
    42781 gctcagcttt ccaagtagag aagcagaata aaatactaaa aatcagatag aaaaaccggg
    42841 cagagagact ggctgatgta acatgccagc ttctctgccc ggttttttac actgcttttg
    42901 caggaaatga tgtttttaca aaaaatgccg ccttacaggc ctgcttccgg ctgaaacatg
    42961 cgaagcccct tggaaatgat ctgctctact aaagaggcca gctgctccgg cgtttccttc
    43021 aggccggagt ccagccagta ctgtaccagg ccgatgcagc cggtgacagt gaaggagtag
    43081 taggcttcaa aggcagagtc gtccagaagt gtgttctggg agctgcggga ggtctgccgg
    43141 ccgccgcctg cgccgggccg gaacagctcc atccagtcct tcaggcactt ttcccggaca
    43201 atatccttca gacggttgac aaaattgatg tctccgttct gtccaatcag aatactgacc
    43261 atatcgctgt tctccttcac cagctggaag acgcgggtga agacgagagc cggattggac
    43321 agcagatcag aagctttgaa atgattcagc acatcatcca gctcctc
//
LOCUS       DBMDUW010000019        40891 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_832_length_40891_cov_4.504021, whole genome shotgun sequence.
ACCESSION   DBMDUW010000019 DBMDUW010000000
VERSION     DBMDUW010000019.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 40891)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 40891)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40891
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_832_length_40891_cov_4.504021"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            224..2011
                     /locus_tag="ACZPCR_05470"
     CDS             224..2011
                     /locus_tag="ACZPCR_05470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013274362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HIR1230358.1"
                     /translation="MDRYGLICRSIWETPGITQRELARLLDVSLGTANRLVNEAIGQG
                     LIKNDINSNNYSLTEQGTEYLRPYKVDGALIMAAGFGSRFVPLTFETPKGLLEVFGER
                     MIERQIKQLHAVGITDITIVVGYLKEKFDYLIDKYQVKLLYNPEYASKNNLATIYHAR
                     EILRGKNMYILSSDNWMRNNMYHAYECGAWYATSYMEGNTSEWCVKTNKKGRITSVSI
                     GGQNCHVLYGPAFFSKEFSEQFLPIINEYYHRPGTEQFYWENAAVDHLADLELYANPQ
                     PEHQIYEFENLEELRLFDPKYQNHSDNEAMSLVSKVFHVPEGDITNIRCLKAGMTNKS
                     FLFELHGDHYICRIPGPGTELLINRKQEEAVYQAVNPLHMTEDIIYFDGETGYKIARY
                     YEGARNADPHSEEDMKLFMQEIKRLHQSGLTVAHTFSLRERIDFYENLCRHRQEMLFE
                     DYTEVRQNMNRLLSLLEQMDRPSCLAHVDCVPDNFLILPDGTGKIIDWEYAGMQDPLI
                     DVAMCAIYSYYNEEETDHLIELYLGRQPECEERFVVYACAALGGFLWCLWAVFKSSLG
                     EEFGEYTLIMYRYAKRYYKKLKLLGEIPE"
     gene            2205..3410
                     /locus_tag="ACZPCR_05475"
     CDS             2205..3410
                     /locus_tag="ACZPCR_05475"
                     /inference="COORDINATES: protein motif:HMM:NF040203.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HIR1230359.1"
                     /translation="MIQKKRLQICGLACLLGALTFSPAMNTFAGWKNTNGTYYHYDDS
                     TGNMTIGWFQEPSNSKWYYLKSDGSMAVGWIQIDGNWYYFDPDGKMATGWRLLDGRYY
                     YMDQQGRMKTGWQQIDGKWYFFSPEGKMRVGWQQIDNNWYYLGENGQMTTGWQKVKDL
                     WYYLDTNGTMMTGWQKINGESYYFHTDGRMLTGWLNDSAGNRYYMSPVSGRMIRGWRE
                     IDQHWYYFNSSGHMVKGWLTENGSYYYLDPSNGMMASDCSKTINNVTYTFAKNGACQT
                     NTNLISGAVQADHLANNSTAGSGSAPGASSPGGGSSGPGGSNSGSSVPGSSNPGTSQV
                     PGSSGNPGSSTAPGSSNTGSSNPGNSTPESSNPGTPNSGGTQAPGSNLGSSNNGYDIP
                     EGLTSGPGR"
     gene            complement(3498..5615)
                     /locus_tag="ACZPCR_05480"
     CDS             complement(3498..5615)
                     /locus_tag="ACZPCR_05480"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase III family protein"
                     /protein_id="HIR1230360.1"
                     /translation="MSDVTNVSEMFGKNVFNDSVMRERLPKSVYKKLKKTIEDGTELD
                     PSIADVVAHAMKDWAIERGATHFSHWFQPLTGITAEKHDSFISVPGSDGRVIMEFSGK
                     ELIKGEPDASSFPSGGLRSTFEARGYTTWDCTSPAFLREDTWGVTLYIPTAFCSYRGE
                     ALDKKTPLLRSMQAINEQALRIIRLFGNTTSKRVIPYVGPEQEYFLVDKEKYLQRKDL
                     IYAGRTLFGAMPPKGQEMDDHYFGSIRPRVGAFMKEVNEEMWRLGVTAKTQHNEAAPA
                     QHELAPIYTQVNVAVDHNQMMMEALKRIAGHHGLTCLLHEKPFAGVNGSGKHNNWSIS
                     TDDGINLLNPGDTPHDNIQFLLVLACIIKAVDVHADLLRESTAVPGNDHRLGAAEAPP
                     AIISIFLGEQLEDVVDQLCSTGLATHTKHGDLLRTGVATLPDFVKDATDRNRTSPFAF
                     TGNKFEFRMVGSSDSVSSPNVVLNTIVAEAFKEAADQLEQAEDFDTAVHDMIKTLLSE
                     HRRIIFSGNGYSQEWVEEAERRGLPNLKIGIDSVDSLITDKAICLFESFGVYTKAELE
                     SRAEIEYESYAKTINIEAKTMIDMAGKQIIPAVIRYTTNLAASLGAVQGACPEADCST
                     QKELLLETSDLLADMKTALAALTDAIGKAAAVANNKERAYAYHDLVTTAMENLRRPAD
                     RLEMIVDKELWPLPSYGDLIFEV"
     gene            complement(5751..6614)
                     /gene="fba"
                     /locus_tag="ACZPCR_05485"
     CDS             complement(5751..6614)
                     /gene="fba"
                     /locus_tag="ACZPCR_05485"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002576541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0030388 - fructose 1,6-bisphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HIR1230361.1"
                     /translation="MLVSAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAEELKSPV
                     ILGVSEGAGKYMTGFKTVSAMVKAMVEELNITVPVALHLDHGSYEGSLKCIEAGFSSI
                     MFDGSHYPIAENVEKTTELVKLCGEKGISLEAEVGSIGGEEDGVVGLGECADPNECKA
                     VADLGIDMLAAGIGNIHGKYPANWPGLRFDVLESIKEKVGDMPLVLHGGTGIPAEMIQ
                     KAISLGVAKINVNTECQLSFAEATRKYIEAGKDLEGKGFDPRKLLAPGTEAIKATVKE
                     KMELFGSVGKA"
     gene            complement(6694..8193)
                     /gene="thrC"
                     /locus_tag="ACZPCR_05490"
     CDS             complement(6694..8193)
                     /gene="thrC"
                     /locus_tag="ACZPCR_05490"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HIR1230362.1"
                     /translation="MEIYYSSTRGKESHVTASQAILKGLADDGGLFMPDKIPSLDRPL
                     REFASMSYQETAYEVMKLFLTDFTEEELKSCISRAYDSKFDTEEIAPLVKADGAYYLE
                     LFHGSTIAFKDMALSILPHLMTTAARKNQVKDTIVILTATSGDTGKAAMAGFADVEGT
                     KIIVFYPKGGVSRVQELQMVTQKGSNTAVAAITGNFDDAQSGVKKIFGDREFAAELSA
                     SGYRLSSANSINIGRLVPQIVYYVYAYAKLLAYGEIEEGEAINITVPTGNFGNILAAY
                     FAKRLGVPVHRLICASNDNKVLFDFFQTGIYDRRREFILTTSPSMDILISSNLERLLY
                     LASGCSADETSRLMSDLSEKGVYEVTPSMKENMKDFVGGFADQKENAEEIRRVFKDTG
                     YLIDTHTGVASAVYRGYRQSSGDQTKTVIASTASPYKFSRSVMEAVCSLDHSEEKLPE
                     DEFELIDKMEQLSGVPQPMAVKEIRDAAILHNRQCSPEDMENMVREILK"
     gene            8438..9151
                     /gene="sfsA"
                     /locus_tag="ACZPCR_05495"
     CDS             8438..9151
                     /gene="sfsA"
                     /locus_tag="ACZPCR_05495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006566347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HIR1230363.1"
                     /translation="MEYINTCKAAFLERPNRFIASARLSDSGVSVVCHVKNTGRCREL
                     LLPGSQLVLEHHPGALKKGRKTEYSLICVYKERAGFSGQTLLINMDSQAPNQAAYEWL
                     ASGGFGSVCHLQREVKFGNSRFDLSFQKDGTLYFMEVKGVTLEQNGTASFPDAPTERG
                     LKHLLELQEAAREGYGAAVLFVIQMKDIRSFTPNRHTHPAFADALKEVSKHGVQILAK
                     DCIVTEHSMTIDQDVPVIL"
     gene            9288..9599
                     /locus_tag="ACZPCR_05500"
     CDS             9288..9599
                     /locus_tag="ACZPCR_05500"
                     /inference="COORDINATES: protein motif:HMM:NF015956.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046914 - transition metal ion binding
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FeoA family protein"
                     /protein_id="HIR1230364.1"
                     /translation="MLNPLSLLTPGQSAVIHWLPEQPAIVSRLLDLGFVPGAAVTCTL
                     RRGNGSISAFLVRNAVIALRKEDAQLILAEPLPSCCAERLPEVQQNSREYDAFKGGDS
                     L"
     gene            9596..10594
                     /locus_tag="ACZPCR_05505"
     CDS             9596..10594
                     /locus_tag="ACZPCR_05505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB small GTPase domain-containing protein"
                     /protein_id="HIR1230365.1"
                     /translation="MKQITAVLAGNPNVGKSTVFNGLTGLSQHTGNWSGKTVSCAEGN
                     FSFGETVCTITDLPGIYSLRTHSEEEEIARSCICSSHPDVLIVVGDATCLERGLHLLK
                     QISQLPDTEDTAIMLCVNLCDEAEKHGILIDFSKLEELLGIPVFRCVARDKKRIEALK
                     ETIVLTSARVISQPEKDFSPEETVSKTVRYTKKNYRKRQDQADRFLTGRFTGSLVMIL
                     LLLLIFWITITGANYPSSFLWEQFFRLETWMAGAFQTAGCPQWLTESLVFGVYRSVAW
                     IVSVMLPPMAIFFPLFTLLEDLGYLPRAAFNMDCAFKKCHACGKQCLTMCVVSASA"
     gene            complement(10665..12185)
                     /locus_tag="ACZPCR_05510"
     CDS             complement(10665..12185)
                     /locus_tag="ACZPCR_05510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008397589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIR1230366.1"
                     /translation="MAELMSELCEKGVELIWKQCNEALFPQGLEYLKEAAEKGDAEAL
                     FFLGHCCSWGDGSVGFNDKKAYEYYLAGAQAGSIRCVLGAARAGQYDDRMKRASRYSL
                     NESFELVAEAAKRGDAFSAYQIAEAFFYEDVYEILPKSERWAGHCFKWYEEAGEGGIV
                     KAMRKAGSFCFSGTYTLKNEKRGLYWAEKAAASGDAWGLLHMGLYTLERQEFEAAFAY
                     FYAASCQGDETSPFYLGELYMNGLGIEQDFSQAAACFEEAARHENREALLRLGELYSE
                     ETFRDDEKAYYWYSRAYGCGKKEAGLALARFCLAPGEHRDLQKAESLLTEYASEDNHW
                     ADQKEACLLLGQMYEGQTEGMPETDWNRAVEYYERGAAQGSEMCKERLGRLYFEGETV
                     VQDYDRAFLFLQECREKGLLQDALPLAFLYQNGYGCEKDERKAAELYLEAANKEKNKD
                     AYYELGKLYERGEQIPQDLEQAVDYYRQAALYGHDGARKCLSHFKRNFFGKWKRVR"
     gene            12334..13266
                     /locus_tag="ACZPCR_05515"
     CDS             12334..13266
                     /locus_tag="ACZPCR_05515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HIR1230367.1"
                     /translation="MNGTMPYRGAIYLRLSKDDESRRESSSISSQRRLLMSYAKEHDF
                     SIVKEYSDDGWSGTTFDRPAFQEMIQDVKKGSINLILTKDLSRLGRNYIVSGQYTEFF
                     FPSMNVRFIAVNDGYDSAVSDSDMIPFKNIMNEMYARDISKKIRSSLRIRMKDGSYIG
                     NFPPYGYEKYPGPPIRLVPDPKASPIVKQIFALGAEGRTPAQIARLLNASHILSPSCY
                     RISKYPQLRESSYPSCGKWTANTILKMLHNPVYLGRMVQGKSRKLSFKSRLTIKNPKE
                     LWIDGGITHEAIVTEELFQACQAAIEKRKCRAGQ"
     gene            13273..14127
                     /locus_tag="ACZPCR_05520"
     CDS             13273..14127
                     /locus_tag="ACZPCR_05520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition domain-containing
                     protein"
                     /protein_id="HIR1230368.1"
                     /translation="MAMGFGCNAVGVTGCRIIDSPRERLIAILTNSLVPCNGRFPTLI
                     TLSLFFMGCFQASKSGIFSIPPSLATALLLTGLILLGIGATLLSSLILSKTLLCGMPS
                     SFTLELPPYRRPQLSKIIVRSVLDRTLFVLGRALLVAAPAGLIIWLSANIQWNGVSLL
                     AHLSGFLDPFGRLLGMDGIILTGFILGFPANEIVIPIILMAYLQTGQLVEMSDQAQLF
                     SLLSAHGWTAKTAVCMAVFSLFHWPCSTTCLTIRKETGSWFWTLTAFLLPTFIGISLC
                     FAMNLLLS"
     gene            complement(14272..15240)
                     /locus_tag="ACZPCR_05525"
     CDS             complement(14272..15240)
                     /locus_tag="ACZPCR_05525"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230369.1"
                     /translation="MGSKTTAGYVLYRVFQTVFAVCVWAVSAAFLSQADELQPPREIL
                     KYSEPEHDPAQLADPPAVFMRENTPYYLASWELSEEELPGRMQYGESSVVYEKVGMNA
                     EIPETAEISMEGENGLFTVPLVRSEYGNQRWEDDFSFTLTFHSCQADTYELGGIEISS
                     DPDSDRPELQGYESELLEMLGLPEAHYRITDYAWAGEAYQDEGGALCRDACARGERLV
                     RDCQAVYGGEVVLSPKKVWRTKAVYRLKDGEGQKQPASGPDQKKREDGQNETAELSWM
                     EEAGRVIKRLTVITVRLGLFLLLLFLLRLLARTGRAVWEKWGRKDG"
     gene            complement(15760..16179)
                     /locus_tag="ACZPCR_05530"
     CDS             complement(15760..16179)
                     /locus_tag="ACZPCR_05530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007706097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease complex subunit PrcB family protein"
                     /protein_id="HIR1230370.1"
                     /translation="MGNMKKLAVWAAGLLLSCVCLLGGCSDKGAEEKVKDLEFTVVGQ
                     NEIPRELMDMIEQKKTEEFRLTYTSGEDLYIAVGYGEQQTGGFSISVPEFYLTENSMV
                     IKTELQGPEQGGQQAASPSYPFIVIKTKFIEEPVVFQ"
     gene            complement(16253..16534)
                     /gene="spoIIID"
                     /locus_tag="ACZPCR_05535"
     CDS             complement(16253..16534)
                     /gene="spoIIID"
                     /locus_tag="ACZPCR_05535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HIR1230371.1"
                     /translation="MKEYIEERAVEIANYIIDHNATVRQTAKKFGISKSTVHKDVTDR
                     LEDINPSLAAQARVVLNINKAERHIRGGLATKEKYQHQLQACSADKKFL"
     gene            16740..18074
                     /locus_tag="ACZPCR_05540"
     CDS             16740..18074
                     /locus_tag="ACZPCR_05540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013272948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015851 - nucleobase transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-xanthine permease family protein"
                     /protein_id="HIR1230372.1"
                     /translation="MKREMNADVSNIYQLEGQVPVMKAIPFGLQHILAMFVSNLTPIT
                     IIAAAGGLAQAEIAVLLQNAMFVAGIATLIQLYPIWKIGSGLPIVMGVSFTFVTVLST
                     VAANYGYPSVIGAVLVGGILEGTLGLLAKYWKKIIAPIVSASVVTSIGYSLFTVGARS
                     FGGGYAEDFGSAENLLLGTITLLVCLIWNIKAKGYRRQLSVLAGLIAGYAAAIFMGKV
                     DFSVIFSSGLISLPKFFPYMPEFHPGAIFSVAIIFFVSAAETIGDTTAMASSGLNRAI
                     TEREITGSLACDGYASAFSSFLGCPPVTSFSQNVGLIAMTKVVNRFTIMTGAACMLLA
                     GLLPPVGNFFASLPESVLGGCTIMMFGTILTSGIEMLSKAGFTQRNITIAALSLSIGI
                     GFTTASETEIWHIFPDIVQSVFSANVVAVVFVVSILLNLILPEDMEMKHSAM"
     gene            18349..19599
                     /locus_tag="ACZPCR_05545"
     CDS             18349..19599
                     /locus_tag="ACZPCR_05545"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="four-carbon acid sugar kinase family protein"
                     /protein_id="HIR1230373.1"
                     /translation="MILLLIIADDFTGALDTGVQFAAHGVSTRVIVDPEVDFSAYHDS
                     VLVIDTETRHLAAGEAFDIVARLTRKAREAGIRYIYKKTDSALRGNIGAELAAVLTAS
                     GCKSLPFLPAFPQTGRVTREGVHYVDGVPVTESPFGIDPFEPVVHSVVTELIGEQCQL
                     PAFSFPALSEASQAPSQEGILVFDASTPSDLLETGKKLAEADMLSIMAGCAGFGAVLP
                     ELLDIAPDRLAALPKLDPRLLVVCGSVNSITLAQLDRAEKAGFSRLRLSPEQKLEPGY
                     WQTERGKEALQGIEDMLASHSHCIIESNDLGGNQPTADYAAALGIDRETLRVRISGCL
                     GYLVGEIFTSPSLGTLLLTGGDTLLQCMNCVGVNELEPLCELDRGVVLARFTYNGCTR
                     HVITKSGGFGQETLLTNLAEQIAD"
     gene            19644..20804
                     /locus_tag="ACZPCR_05550"
     CDS             19644..20804
                     /locus_tag="ACZPCR_05550"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002596031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004308 - exo-alpha-sialidase activity
                     [Evidence IEA];
                     GO_function: GO:0016997 - alpha-sialidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sialidase family protein"
                     /protein_id="HIR1230374.1"
                     /translation="MTYPKLPGLTWDGTIYENEEMGTCEALLPTGGYPTAHAPAMAEL
                     PNGDLLCCWFAGTYEGSADIHVICSLLPKDAPAWLPPVEVSGDPERSEQNPSLFYGPD
                     NAVWAMYTAQLDRQEGKDNMQFTSVVRCQKSTDGGKTWGPYETIFPEEGTFCRQPIQV
                     LSNGRWIFSNWICTDSADGLSGDPTAFRISDDQGKTWKKVMMPESNGHVHANVVELEP
                     GHLAAFMRNREAYRIHRSESFDWGETWTKPEPTPLPNNNSSISAVKLQSGRIAIAYNP
                     TCTPDPQPGKAAWPGLRCPVAVALSEDGGLTFPIIRWMERGEGFIGDENKTNNKQYEY
                     PYLMQTRDGMLHLAYAARTRQGVKYVRFSEQDVLGEKRERVGLYNPTAAQSR"
     gene            20842..22005
                     /locus_tag="ACZPCR_05555"
     CDS             20842..22005
                     /locus_tag="ACZPCR_05555"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008397606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HIR1230375.1"
                     /translation="MLTTYNLKMPHAVYGGENAMDNITSILKSNGVKRVAMFTDKGIE
                     EAGLFALPEEAVKAAGAEYYVLDDLPAEPSYMAVQKLVDEFKASKADMIVACGGGSVM
                     DAAKLASILVTDEYGVKELLDDPGRAKKCVPIILIPTTAGTGAEVTPNAIVAVPEKEL
                     KVGIVNENMIADYVILDARMIKNLPRKIAAATGVDALAHCIECFTSNKANPFSDLYAL
                     EGLDLILNNIEKACDDPEAMTEKNRMQIAAYYGGLAITASGTTAVHALSYPLGGKYHI
                     AHGVSNAILLAPVMRFNEPACQERFAIAYDRCCHDEVKTCRTNAEKSAWIISRLEEIV
                     KHLDIPTSLKEFGVPEEDLDGLVEAGMQVQRLLVNNPRQVTPEDARKLYLEIL"
     gene            22065..22973
                     /gene="dapA"
                     /locus_tag="ACZPCR_05560"
     CDS             22065..22973
                     /gene="dapA"
                     /locus_tag="ACZPCR_05560"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006773812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HIR1230376.1"
                     /translation="MKPVEIKGIIPPILTPMNDDESINVAELRNQVDRMIEGGVHALF
                     PFGTNGEGYILNAKEKQLVLETVIEQCNGRVPVYAGTGCISTKETIEQSKMAQAAGAD
                     VLSIITPSFAAASQDELYAHYKAVAEAVDMPIVLYNIPARTGNALAPATVARLAQIEN
                     IVGAKDSSGNFTNILGYIDAGAKKTNGKFCTLSGNDQLIIWTLLAGGTGGIAGCANVY
                     PHTMASIYNLFMEGKIEEAKAANASIQSFRACFKYGNPNTIVKTATRLLGYNVGPCRA
                     PFNQVPEEGIQALKKVLAENEAKGMR"
     gene            22991..24061
                     /gene="pdxA"
                     /locus_tag="ACZPCR_05565"
     CDS             22991..24061
                     /gene="pdxA"
                     /locus_tag="ACZPCR_05565"
                     /EC_number="1.1.1.262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005944587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050570 - 4-hydroxythreonine-4-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase
                     PdxA"
                     /protein_id="HIR1230377.1"
                     /translation="MNAKPIVGITMGDPAGNGPEITVKALAHAEVYDSCRPIVVGDVK
                     IIEQAARFVGRPDITIHRCEKVSDARFQQGVIDVLHLELIPDVEKFPIGQVSIEGGNA
                     AFQCVKKVIELALAGEVDATCTNALNKEAMNKALEFYHGENSDGYTHFDGHTEIYATY
                     TNTKKYTMMLAHHDLRVVHVSTHVSLREACDRVKKARVLEVIEIAHKACKDMGIENPK
                     VAVAGLNPHCGENGLFGTEEIEEIKPAIEAAKAEGINAIGPIPPDSVFSEALGGWYDI
                     VVCMYHDQGHIPLKTVGFVYDRELQAWKAVEGVNVTLGLPIIRTSVDHGTGFALAGKG
                     TSNELSLVNAIDYAVRMAKGRN"
     gene            24417..25691
                     /locus_tag="ACZPCR_05570"
     CDS             24417..25691
                     /locus_tag="ACZPCR_05570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002596032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HIR1230378.1"
                     /translation="MTTQMIIALAITALMVVLIMMDKLPFGAPPLLACLLLVIFGIAD
                     IKAAFGGFSNATIVMLAEFMAIIAALQKTSFIANFKKTMFKIANQGGIKAYMLMILIV
                     MLGCSLFGTGSTAYYVMVIGFLSTLPYTKKLPPSKVVMTAGFAANHPLIPFNTALQYG
                     IVIAVLNSAGIAANIPVSKFAIVNLFLSLGFLLNCVIQYKFLPDHPIAASTDAAVSED
                     AAPSLPKWKEQVTYFVFILAVVGMLLQSKIGDAGYAIAGISVGVILVTGVMDFKEIRD
                     SISAPIILMSAGVIGVADALGSTGLTDLVGSTVANMLGTNVNPFVMIFVFCILTSVLA
                     TLTGSTIGTVYVFAPLAIATCTSLGLDPTAAACAIVISGWCGHFLPIDGMPAMVMGVG
                     NYSSKEFCKFTIPQYFIRLLALTAGALLVFPM"
     gene            25726..26073
                     /locus_tag="ACZPCR_05575"
     CDS             25726..26073
                     /locus_tag="ACZPCR_05575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HIR1230379.1"
                     /translation="MKNKFELEHVGINTPNPEEAEKLAQLLSLVFNLEPRHGQKSEFA
                     GPYFECMKAPFLGTNGHIAMRTPDLTAAAEELKEKGFDLNMDTAAYTEDGKLKNVYLA
                     GEFGGFAIHIMQK"
     gene            complement(26168..27529)
                     /locus_tag="ACZPCR_05580"
     CDS             complement(26168..27529)
                     /locus_tag="ACZPCR_05580"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HIR1230380.1"
                     /translation="MKKRHKGLSIKARVTLWYTFFMILVFGITAVYLVSSSQRMSGRQ
                     MRERLVDTVTDAVSQVRFRYGELDAEELDFYKNGVSVFLYDTQGRLLAPKVTRGIQVD
                     SLLEDQTIKTASSGRERWMIYDVYSEGEDAGFWVRGMISMTEYGQALGNLPILFGSAL
                     PLLAVLAALGGFRITRRAFRPVTQMAETARAIGTGSDLSQRIETDGRGDELNQLGDTM
                     NEMLARLQASFEAERQFSSDVSHELRTPIAVIRSQCEFALSGQAGEEEKREAFEAVLK
                     QSERMNSIVSQLLLLSRAENGKFVPEREPVELNVLCETVCEELEAMAAERQVELTWNT
                     EELQITGDETLLIRMVNNLVSNAIRYNRPGGSAEVSLRKRGKYAVLTVRDTGIGIRRE
                     DLGQIFSRFYRADRSRSSEGTGLGLSMAAWIARVHGGSIRAESVYGEGSVFTAELPIE
                     EQA"
     gene            complement(27533..28204)
                     /locus_tag="ACZPCR_05585"
     CDS             complement(27533..28204)
                     /locus_tag="ACZPCR_05585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIR1230381.1"
                     /translation="MRILFAEDEPDLREITIKRLRAAGFGADGCPDGEEALYYLEHTE
                     YDVAILDIMMPNMDGLTVLRTLRSRGSQIPVLLLTARDSVGDRVGGLDAGADDYLTKP
                     FEFEELAARIRALLRRRSPEKTDAVSVGDLTVEFSTRRVIRGGKEINLSSKEFALLES
                     LIRHKGAVLSRTQLENQVWDYGFEGGSNIVDVYIRYLRKKLDDPFEKKLIHTIRGAGY
                     TLREE"
     gene            28406..29092
                     /locus_tag="ACZPCR_05590"
     CDS             28406..29092
                     /locus_tag="ACZPCR_05590"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230382.1"
                     /translation="MKRNDNPYDKMLNTAGRAAKAAASGLLLALLLAGCSQKNPVKTQ
                     PISSMESSSEALGETSQTAAASEISPSASGTAGSIETDAESYYRAKAEQDAIHIDIAK
                     LEADFRVGKLSKEDFAAQKSQLEAEKDALDREEDRLEDSLDLAYSQSSPALPSGSLEE
                     LRSMASELEQKEHQLEAQEDALEQSYWSGDVARDEFIAQQIELIRTEETMDREADLLE
                     DALEAMGFDD"
     gene            complement(29073..30752)
                     /gene="recN"
                     /locus_tag="ACZPCR_05595"
     CDS             complement(29073..30752)
                     /gene="recN"
                     /locus_tag="ACZPCR_05595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003509436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HIR1230383.1"
                     /translation="MLFHLSVRNLALIDSAEVEFEEGLNILTGETGAGKSVIIGSVNA
                     ALGGKTSKDMIRQGCDYAYVELVFSVTDEKKRRELAAREVCPDADGNLIISKKIMPSR
                     SISRINDETVTAARLREITGILIDIHGQHEHQSLLYHAKHLEILDEYGKSRIAKLKEQ
                     TAEAYQEYAAVKKKLEYYQSGREQLLRETDFLRFEIEEIENAGLKPGEEEELESAYRR
                     FSNSRRIVESLSEAYQAVNGDAVARALLAVEKAAEYDEGISGIRDQLYDVDALMSDLN
                     REISSYMEEMTFDEAAFRETEERLDLIRGLENKYGDTIEKVLDSLDKKREKLEELEHF
                     DLRREETERRFAQLEERLETLCGELSKIRRETAQTLTERMREGLSDLNFLNVEFTMEF
                     RRLSHYTAGGFDEAEFLISTNPGEPPRPLGAVASGGELSRIMLAIKAVLAETDDIPTL
                     IFDEIDTGISGRTAQMVSEKLSLIAGSHQVICITHLPQIAAMADSHYEIRKTAKENRT
                     VTQIKRLSEDQMTDELARLLGGAEITEAVRQNAREMRALAAEKKRLNRQTP"
     gene            complement(30797..31249)
                     /gene="argR"
                     /locus_tag="ACZPCR_05600"
     CDS             complement(30797..31249)
                     /gene="argR"
                     /locus_tag="ACZPCR_05600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009266019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HIR1230384.1"
                     /translation="MKLERHSKIVELIGKYNIETQEELAEYLNKEGYNVTQATVSRDI
                     RELKLSKIQGEHGRQKYAVFHPQQTAFNDKYIRILRDGFLSMDMAQNILVIKTVAGMA
                     MAVAAALDAIHFSEVVGCIAGDDTIMCAVRTVDDTILLMDKLKKIVNH"
     gene            complement(31278..32144)
                     /locus_tag="ACZPCR_05605"
     CDS             complement(31278..32144)
                     /locus_tag="ACZPCR_05605"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0006741 - NADP+ biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019674 - NAD+ metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HIR1230385.1"
                     /translation="MKYFYMIVNHSKKKAEYGAELIRDYLEGRGCECVVWDASDTDAC
                     RSRRLQFRYTDREAVPGWIECAIVLGGDGTLIQAARDLAGSNIPLLGVNMGTLGYLAQ
                     IGREEDILPALDELIADHYGLEQRIMLKGTVISDGRVIAEDIALNDIVLSRMGLNMLR
                     FNLSIDGEFLNDYSADGIIAATPTGSTAYNLSAGGPIAVPDSEMILLTPICPHTLNSR
                     SVVLAPDRVIELEITGRGETGKFLSFDGDTQVNLKNGDLVRIERSETVTTLIRLKKVS
                     FLENLRDRMKQI"
     gene            complement(32205..33011)
                     /locus_tag="ACZPCR_05610"
     CDS             complement(32205..33011)
                     /locus_tag="ACZPCR_05610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HIR1230386.1"
                     /translation="MKERLDVLLVKHGLAESREKAKAIIMSGIVYVDGQKEDKAGTTF
                     DEKARVEVRGAVLKYVSRGGLKLEKAMTHFGVELNGKVCMDVGASTGGFTDCMLQNGA
                     VKVYSVDVGHGQLAWKLRNDPRVVCMEKTNIRYVTPDDIGDPVEFSSIDVSFISLTKV
                     LGPVKELLTEDGQIVCLIKPQFEAGREKVGKKGVVREKSTHLEVIETVISFAKAIGFQ
                     ILNLEYSPIKGPEGNIEYLLHLQNNGSGGEEELSVSPKDVVEAAHRELDK"
     gene            complement(33023..34882)
                     /gene="dxs"
                     /locus_tag="ACZPCR_05615"
     CDS             complement(33023..34882)
                     /gene="dxs"
                     /locus_tag="ACZPCR_05615"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002601003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HIR1230387.1"
                     /translation="MILERINGPDDIKKLKDGELAVLAEEIRSFLIEKISRTGGHLAS
                     NLGVVELTMALFLAFDLPKDKIIWDVGHQSYTHKILSGRKENFDGLRQYGGLSGFPKR
                     KESPFDAFDTGHSSTSISAGLGMALGRDVRGDDYSVISVIGDGALTGGMAYEALNNAA
                     QIKKNFIIVLNDNNMSISKNVGGISSYLSNLRADEGYNELKKSVVAALRSIPRVGNSM
                     VQTLTRTKNGIKQLLIPGMWFENMGVTYIGPVDGHNVRQLVRIFKEAKKMDHAVLIHV
                     LTKKGKGYEPAEKNPSAFHGVEPFDMETGKPLAAKIYPSYTDIFSKTICQIAEKDKRV
                     AAVTAAMPGGTGLSRFEKLYPERFFDVGIAEEHAVTSAAGMAAAGLRPVVAVYSSFLQ
                     RAYDQILHDVCIQNLPVLFCVDRAGLVGSDGETHQGIFDLSFLSSIPNMSVMAPKNLW
                     ELREMIRFGVNYDGPMAIRYPRGQAYRGLKEALAPIEYGKSEMLFEESEIALLAVGSM
                     VSTAEHVRLKLKNMGVSCTLVNGRFIKPVDTDIVDRLAKNHRVIVTLEENVLRGGYGE
                     RITDYAAKRYPELKVLNIALPDAYVEHGNVSLLRSDLGIDSDSILKKIKEHFL"
     gene            complement(34902..35789)
                     /locus_tag="ACZPCR_05620"
     CDS             complement(34902..35789)
                     /locus_tag="ACZPCR_05620"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HIR1230388.1"
                     /translation="MELREQLLQYTKETEDVVYSFLPKEEGHQKTIFEAMNYSVKAGG
                     KRLRPLLMREVYRLFGGTGKEIEPFMAAIEMIHTSSLIHDDLPCMDNDEYRRGRKTTW
                     VAYGYDMAVLSGDALLIYAIETASRAFAMTAHADRVGRCIGILAEKTGIYGMIGGQTV
                     DVELTNQPVSREQLDFIYQLKTGALLEASMMIGAVLAGASKEELQTVERIAANVGLAF
                     QIQDDILDVTSSQEVLGKPVGSDEKNNKTTYVTLEGMEKAKAEVERLSDDALKLLAGL
                     PGRNEFLEALIRLLIHREK"
     gene            complement(35779..36024)
                     /gene="xseB"
                     /locus_tag="ACZPCR_05625"
     CDS             complement(35779..36024)
                     /gene="xseB"
                     /locus_tag="ACZPCR_05625"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HIR1230389.1"
                     /translation="MEEKGRLPEPNQEELEACSIEELFERLNQVIGGLEDGSSSLEDS
                     FRYYEEGMRLVKACSGKIDRVEKQILVIDEMGGDYGA"
     gene            complement(36043..37266)
                     /gene="xseA"
                     /locus_tag="ACZPCR_05630"
     CDS             complement(36043..37266)
                     /gene="xseA"
                     /locus_tag="ACZPCR_05630"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007860448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HIR1230390.1"
                     /translation="MASIYSVSQVNAYIKNMFSQDFALNRISIKGEVSNCKYHTSGHI
                     YFTLKDGLAAIQAVMFASRRKGLPFQMQDGQQVVVKGSVEVYERDGRYQLYAQQIELS
                     GAGDLFKRFEALRNQLEEMGMFAREYKRPIPMFARTVGVVTASTGAAIRDIMNISHRR
                     NPYVQLILYPAKVQGDGAAESIAMGIERLDQLGVDVIIAGRGGGSIEDLWAFNEEIVA
                     RAIFSCNTPVISAVGHETDVTIADYVADLRAPTPSAAAELAVFDYRQFKEQLSGAGEL
                     LRRGLFRKTEEASGRLEQYRLRLRLHDPKRQVNEKRQRLISAQDDLKRLMEKRLSEYR
                     QRLALLSGRLEGCSPLKKLSQGFGFVTDETGKRVDSVNKVMPGEKIEVRTADGRIDAR
                     VEAVFPYSRRDCHGE"
     gene            complement(37280..37723)
                     /gene="nusB"
                     /locus_tag="ACZPCR_05635"
     CDS             complement(37280..37723)
                     /gene="nusB"
                     /locus_tag="ACZPCR_05635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002601007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HIR1230391.1"
                     /translation="MTRRELREHCFKLLFCADFYSEGETREQIEQYFTEPREDDYTPE
                     GVYELIHCPELDVYDSGYVKTKVEKVLEKRPELDAAIDETAKGWSTRRMGKVELTILR
                     LALFEIRFDEEVPDKVAINEAVELAKKFGGDESPAFVNGILAKLV"
     gene            37970..39616
                     /locus_tag="ACZPCR_05640"
     CDS             37970..39616
                     /locus_tag="ACZPCR_05640"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HIR1230392.1"
                     /translation="MKAKRIIKSGLALLLSMQLALMSCITALAAPEWPSGTGVLADIG
                     IAVDADSGAVLFGQGIHELTPPASITKLLTALVVVENSSMDDMVTFSYDAVNNVESGS
                     GNKKNIAEGDKLSVKDCLYLLLLQSSNQAANALAEHVAGSRDAFADMMNEKVKELGCT
                     DGTHFANPSGLNDDTQVVSAYDMAIIAQAAFNNSDVLEISSTKSYKLAPTQNNPSGAT
                     CANEHRLIITDDETSELYCPEAKAGKTGYTSLAGNTLVTYGEKDGRRVISVVLKGQPS
                     PNYFLDGKTLLQFGFENFQNVSIPDNETKYVTGEETVSINGADFQPDELELESGAVIT
                     LPKDAAFSDASMELVTELPEQHPERAIALLQYTYNDRKIGQAYLLAKEGSLPASSEET
                     DGAAPEEKPGGKTDASDQKDGKEGSIALPPLSLPVIGICLLVFAVLLLSAYTLYTKKK
                     EAEELRRRHERRMQRLKEENYTEEEFYELLGREKERLAGKRSQKRSSGSRPKKAEKKA
                     RSPKQMKTEGESPDESLENLDDLFFEDLDSSEENKNNFDI"
     gene            39915..40124
                     /locus_tag="ACZPCR_05645"
     CDS             39915..40124
                     /locus_tag="ACZPCR_05645"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230393.1"
                     /translation="MGTVVLYNIISLIVIFVLVFALKIVNKSDLRRNQQLIIKVIAAI
                     LIVCVITFILFIDAIAVGIIGLVPN"
     assembly_gap    40131..40140
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <40141..40818
                     /locus_tag="ACZPCR_05650"
     CDS             <40141..40818
                     /locus_tag="ACZPCR_05650"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230394.1"
                     /translation="QNAKRSKKTEHIKRCLNMPAYFSLTFELKKTHDAIGAFCRALIH
                     SGLTFKSGYWGFENDSFEDMIQWNQKKLDENFELGEKEHHSHDYKQFVFDYFDFSEVR
                     LFIMNNQKESTFTFELIVPEDDLGEYEEKENGKYSVQRNTKRMEQLKSLAKNVWIHSS
                     VLAIQTSWECSSCPPAAEKIAAGMKPQAEPFCILNSSSLKNETDFVFESLERNGVLIE
                     NITQWNY"
BASE COUNT         9667 a        11428 c         9354 g        10432 t
ORIGIN      
        1 cctatatcat aatatacctg cacccaaaat acaataacat ttctctgttc attttcttac
       61 agaatcatta cagtaataga aaattaaggc aaaattgtac ttatatcaat acaatcttaa
      121 gatttccact gtactttctc gaatttcatg gtataatgtt catattcttt gatgtgacat
      181 tgttttttga acattaaaat ttatctttag aaagaggtta aatatggatc gatacggctt
      241 aatatgccgg agtatttggg aaactcccgg cattacgcag agggaactgg cccggctcct
      301 ggacgtttct cttggaacgg caaaccgcct ggtcaatgag gccattgggc agggattgat
      361 taaaaatgat ataaattcaa ataattattc actgacagaa cagggaacag agtacctccg
      421 accttataaa gtagacggag ccctgattat ggccgccggc ttcggctccc gttttgttcc
      481 ccttaccttc gaaactccaa aaggtcttct ggaggtcttt ggggaacgca tgattgagcg
      541 gcagattaag cagctccacg ctgtcggcat tacagatatt acgattgtgg taggctacct
      601 gaaggaaaag ttcgattatc tgatcgataa gtaccaggtt aaactcctct acaatccgga
      661 atatgcttcc aaaaataatc tggccaccat ttatcatgcc agggaaattc tgcgcggaaa
      721 aaatatgtac attctctctt ctgacaactg gatgagaaac aatatgtacc acgcttacga
      781 gtgcggcgcc tggtatgcta cctcctacat ggagggcaat acctccgagt ggtgcgtgaa
      841 aaccaataaa aaagggcgga tcacctctgt ctccatcgga ggccagaact gccatgtttt
      901 atatggcccg gccttcttct ccaaagagtt ttcagagcag tttcttccta ttataaatga
      961 gtactatcac aggcctggca cagaacaatt ctactgggaa aacgcagcgg ttgatcatct
     1021 ggctgatctg gagctgtacg ccaatcctca gccggagcat cagatctatg aatttgaaaa
     1081 tctggaggag cttcgtctct ttgatccgaa ataccagaat cactctgaca atgaggctat
     1141 gagcctggtt tccaaagtgt tccacgttcc ggaaggagat attacaaata tccgctgtct
     1201 gaaggcaggc atgacaaaca agtcttttct gtttgagctg cacggagacc actacatctg
     1261 ccggattcca gggccgggaa ctgagcttct tattaaccgg aagcaggagg aggctgtgta
     1321 tcaggctgtc aatccgctcc atatgacgga ggatatcatt tattttgacg gggaaactgg
     1381 ctataaaatt gcccgctact acgagggtgc ccgcaacgcg gatccacaca gcgaggagga
     1441 catgaaactg tttatgcagg agatcaagcg tctgcaccag tccgggctta cggtagcgca
     1501 taccttttcc ctgcgggaac ggatcgattt ctatgaaaac ctctgccgtc acaggcagga
     1561 aatgctgttc gaggactaca cagaagtccg ccagaatatg aaccgccttt taagtcttct
     1621 ggagcagatg gaccgtccct cctgcctggc ccacgttgac tgcgtccctg acaacttcct
     1681 gattctgccg gacggaaccg gaaaaatcat tgactgggag tacgccggaa tgcaggatcc
     1741 gctgatcgat gtggccatgt gcgccattta ttcctattat aatgaagaag aaaccgatca
     1801 tttaattgaa ctctatttag gaaggcagcc ggaatgcgag gaacggtttg tggtttatgc
     1861 ctgcgccgct ctaggcggat tcctgtggtg tctctgggct gttttcaaaa gctccctggg
     1921 ggaggaattc ggagaatata ccctgattat gtatcgatac gcgaaacgct attacaaaaa
     1981 gctgaagctc ctgggcgaaa ttccagaata atccccggct gcggtatacc tcttttctct
     2041 catttgtggt ataataggta cacttgacga ggtttttcac gagtctggtg agaatacata
     2101 tctgtcccac tcagccaggt cttttcgagc ttagcgggca tggtatacta tcgtcacctt
     2161 ttctccgata caaaagttta ctgtacgcat caggaggcat tttcatgata caaaagaagc
     2221 gtttgcaaat ttgcgggctg gcctgtcttc tcggcgctct caccttttct ccggctatga
     2281 atacctttgc cggatggaaa aatacgaatg gtacctacta tcactacgat gacagcaccg
     2341 gtaatatgac aatcggatgg tttcaggagc catccaattc taaatggtat tatttaaaaa
     2401 gcgacggttc catggcagtc ggctggattc agattgacgg aaactggtat tactttgatc
     2461 cggacggaaa gatggccacc ggatggcgtc ttctggacgg ccgctattac tacatggatc
     2521 agcagggacg aatgaaaacc gggtggcagc agattgacgg gaagtggtat ttcttcagcc
     2581 cggagggaaa aatgcgcgtc ggatggcagc agatcgacaa taactggtac tatctggggg
     2641 aaaacggcca gatgacaacc ggatggcaga aagtcaagga tttatggtat tatctggata
     2701 caaacggaac tatgatgacc ggatggcaga aaatcaacgg agaatcctac tatttccata
     2761 cagatggacg gatgctcacc ggctggctca acgacagcgc cggaaaccgt tactatatga
     2821 gtcccgtatc cggccgcatg atacgcggat ggcgggaaat tgatcaacat tggtattatt
     2881 ttaacagcag cggacatatg gtgaagggct ggctgacgga aaacggatcc tattattacc
     2941 tggatccatc caacggtatg atggcctccg actgctctaa gaccattaat aatgttacat
     3001 acaccttcgc caaaaatggc gcctgccaga ccaatacgaa tctgatcagc ggagctgttc
     3061 aggcggatca cctagcaaat aacagtactg ctggttccgg aagcgcccca ggcgcttcct
     3121 cgcctggcgg cggatcatcg ggacctggcg gctcaaattc cggaagttct gtcccaggaa
     3181 gctccaatcc tggcacaagt caggttcccg gcagctcagg caatcccggc tcttccaccg
     3241 ctccaggaag ctccaacacc ggaagttcca acccaggaaa ttccaccccc gaaagctcca
     3301 atcctggaac gcctaattca ggcggaactc aggctcccgg cagtaatctg ggttcctcca
     3361 ataacggtta cgacattcca gagggcctga caagcggccc aggacgataa aaagcgcccc
     3421 cgcagaacca taccatgtgt attacactta tgggtatgcc ctgggggcgc tttttgatta
     3481 tttcttctga ttatggatta cacttcaaaa atcaaatctc cgtagcttgg cagaggccac
     3541 agctccttat ctactatcat ctccagacga tcggccgggc ggcgcaggtt ttccatggcc
     3601 gtggtcacta aatcgtggta tgcgtaggcc ctctctttat tgttcgcaac tgccgccgct
     3661 tttcctatgg cgtctgtcaa ggccgcaaga gctgtcttca tgtcagccag caaatcagac
     3721 gtttccagca aaagctcttt ctgtgtactg cagtctgcct ccgggcatgc gccctgaacc
     3781 gctcccagag aagccgccag attcgtagta taccgaatca cagccggaat aatctgtttt
     3841 cccgccatgt caatcatggt tttagcctca atgttgatag tctttgcata ggactcgtac
     3901 tcaatctcag ctctggactc cagctctgcc ttcgtgtaaa cgccaaagct ttcaaataaa
     3961 cagattgcct tatctgtgat cagagaatcc accgagtcaa ttccgatttt taagttcgga
     4021 agtcctcgtc tctcggcctc ctccacccac tcctgagaat atccgtttcc gctgaaaatg
     4081 attctcctgt gctcagacag cagggtcttg atcatatcgt ggaccgctgt atcgaaatcc
     4141 tccgcctgct ccagctgatc tgccgcttct ttaaacgctt ctgccacaat cgtattgagc
     4201 actacgttag gagaggagac agaatccgag gatccaacca ttcggaattc aaatttattt
     4261 cctgtaaatg caaacggtga agttctgttt cggtcggtag catccttcac aaagtcagga
     4321 agcgtggcaa ctcctgttct cagtaaatcg ccatgttttg tgtgggttgc caggcctgtg
     4381 ctacagagct gatccaccac atcctccagc tgctcgccca ggaaaataga gataatcgca
     4441 ggcggagcct ccgctgcgcc taaacggtga tcatttcccg gaacggctgt agattcccgc
     4501 agaagatccg cgtgtacgtc cactgccttg ataatacatg ccagaacgag caggaactgg
     4561 atattatcgt gaggcgtatc tcctggattt aacagattaa tgccgtcatc ggtagaaatc
     4621 gaccagttat tatgctttcc ggaaccattg actccggcaa agggcttctc atgaagcagg
     4681 caggtcagac catggtggcc tgcgatccgc ttgagggcct ccatcatcat ctgattgtgg
     4741 tcaactgcga cgttcacctg agtataaatc ggcgccagct cgtgctgggc cggggccgcc
     4801 tcgttgtgct gagtcttcgc cgtaacgccc agacgccaca tttcctcgtt gacttccttc
     4861 ataaacgcgc cgactctggg gcggatgctt ccaaaatagt gatcgtccat ctcctgtccc
     4921 ttgggaggca tagctccaaa cagcgttctt cctgcataaa tcagatcttt tctctggaga
     4981 tatttttcct tatctaccag gaaatactcc tgctccgggc ctacataggg aatcacacgc
     5041 ttggatgtgg tatttccaaa caggcggata attctgagcg cctgctcatt aatcgcctgc
     5101 atggaacgga gaagaggcgt tttcttatcc agagcctctc ctctgtaaga acagaaggcg
     5161 gtaggaatgt aaagcgtcac gccccaggta tcttcccgca aaaatgccgg agaagtgcag
     5221 tcccaggttg tatatcccct ggcctcgaaa gtggagcgca gtcctcctga cgggaaggat
     5281 gaagcgtccg gctctccctt tatcagctct tttccagaaa attccatgat cacgcggccg
     5341 tcgcttcccg gcacggaaat aaaggaatcg tgcttttcag ccgtgatgcc tgtgagaggc
     5401 tgaaaccagt gtgaaaaatg ggtcgctcct ctctcaatag cccagtcctt catggcgtgg
     5461 gctaccacat cggcgatgga cggatccagc tctgttccat cttcaatggt cttttttaat
     5521 ttcttataga cgctcttcgg aaggcgttct ctcatcaccg aatcattaaa tacatttttt
     5581 ccgaacattt cggacacatt tgtgacgtcg ctcatcgtat attcctccaa gttatcgttc
     5641 agaccagtct gcctgccgta taaaagaaca aaataagcct gcctgaagct gacttctgac
     5701 tgcgtgccag aaatctgccc agaccggctt atctatgttt taaactttgt ttatgctttt
     5761 cctacggaac cgaataattc cattttttct tttacagttg ccttgatagc ctctgttcca
     5821 ggagccagaa gcttacgcgg gtcgaagccc tttccttcca gatccttgcc agcctcaatg
     5881 tacttgcgtg tcgcctctgc aaaggataac tggcactctg tatttacatt gatcttcgca
     5941 acgcctaaag aaatcgcttt ctgaatcatc tcagccggga ttcctgtacc gccgtgaaga
     6001 acaagcggca tatcgcctac cttctccttg atggactcaa gtacgtcgaa tcttaagcct
     6061 ggccagttag ccggatattt tccatggata tttccaattc ctgctgccag catatcgatt
     6121 ccaaggtcag ctactgcctt gcactcgttc ggatctgcgc actcgcccag gcccactacg
     6181 ccgtcttcct cgccgccaat ggaaccaacc tctgcctcaa gagaaatgcc cttctctccg
     6241 cagagcttta ctaactctgt tgtcttctct acgttctctg caatcggata gtgagagccg
     6301 tcaaacataa tggaagagaa tcctgcctca atgcacttta aggagccctc gtaggagccg
     6361 tgatccagat gcagcgctac agggactgta atgtttaact cctctaccat agccttaacc
     6421 atagcggaaa ctgtcttgaa acctgtcata tactttcctg cgccctcaga tactccaagg
     6481 ataaccgggg actttaactc ctctgctgta agcagaatgg ccttcgtcca ctccaggttg
     6541 ttaatgttaa actgtccaac tgcatacttg ccttctctgg ccttgttaag catttctttc
     6601 gctgatacta acatatcatt gaacctcctt cgcatttctc tacttgcctg cgcctattat
     6661 ataccatttt tctctatttg aaaagcctgt tccttatttt aaaatctctc tgaccatatt
     6721 ctccatgtcc tcagggctgc actggcggtt gtggaggatg gccgcgtcgc ggatttcctt
     6781 caccgccatg ggctgcggca cgccggacag ctgttccatc ttatcgatca gctcaaactc
     6841 atcttctgga agtttctcct ccgaatgatc caggctgcag actgcctcca tcacgcttct
     6901 ggaaaatttg taggggctgg cagtagaagc aattaccgtc ttcgtctgat ccccgctgct
     6961 ctgtctgtaa cctctgtaca cagccgacgc cactcctgtg tgggtatcga tcagatatcc
     7021 cgtatctttg aatacacgtc tgatctcctc tgcattctcc ttctgatctg caaatcctcc
     7081 cacaaagtcc ttcatatttt ctttcatgga aggcgtaacc tcgtacacgc ccttctcaga
     7141 aagatctgac atcagccgtg aagtctcatc tgcgctgcag ccggacgcca gataaagaag
     7201 cctctccaga ttgctggaaa tgagaatatc catagacggg gaggtggtaa gaataaactc
     7261 tctgcgtctg tcgtaaattc ctgtctggaa aaagtcaaac aataccttat tgtcattgga
     7321 agcgcagatc agcctgtgaa ccggaactcc caggcgcttg gcaaaataag cagccagaat
     7381 atttccaaag tttccagtag gaaccgtgat attaatggct tctccctctt caatctctcc
     7441 gtaagccaga agcttcgcat atgcgtaaac ataataaaca atctgcggca ccagacggcc
     7501 gatattaata gagttggcgg acgaaagtct gtaaccggaa gcggaaagct ctgcggcaaa
     7561 ttcccgatct ccgaaaatct ttttcacacc gctctgggcg tcgtcaaaat ttccggtaat
     7621 cgctgcaacc gcagtgttgc ttcccttctg ggtcaccatc tgaagttcct gtacccggct
     7681 cacgcctccc ttaggataga aaacaatgat ttttgtcccc tccacatctg cgaagccggc
     7741 catagcggcc tttcccgtat cgcctgaagt agccgtaagg attacgatgg tatcctttac
     7801 ctgatttttt ctggccgctg tcgtcataag atgaggcaga atggaaaggg ccatatcctt
     7861 aaatgcaatc gtacttccgt ggaacagctc cagataataa gctccgtcag ccttcacaag
     7921 gggagcaatc tcctctgtgt caaatttgga atcataggct ctggaaatac aggatttcaa
     7981 ttcctcttct gtaaaatctg tcaaaaacag cttcataacc tcataagctg tctcctgata
     8041 gctcatggac gcaaactctc ttaacggccg gtctaatgac ggaatcttat ccggcataaa
     8101 cagtcctcca tcgtctgcca gaccttttaa aattgcctgg gaagccgtca catgggattc
     8161 ttttcctctg gtgctgctgt agtagatctc cattcctctc atcctctttt ctttattaat
     8221 gcaatgcttg aggcatctgc ccttccgctg gagccgcctg ctccatagac gccggcacat
     8281 cccttatatt tttcaaaatt ctatcatatt tcttttaaat atgcaatgtc attgcatttt
     8341 ttctcctcct ggtgcaaaat aaaggctgaa cgtttcctat cggtcggtga atgcgcgcat
     8401 ccctgactgc aaacttatct gtataaggag aacatttatg gaatatatca atacctgtaa
     8461 agccgccttt cttgagaggc ccaaccgttt tatcgcttcg gcccgtctct cagattccgg
     8521 cgtttccgtt gtctgccacg ttaaaaatac tgggagatgc agggaactcc tgcttccagg
     8581 ctcccagctg gttctcgagc atcaccccgg cgctctgaaa aaagggcgaa agaccgagta
     8641 ttctctcatc tgtgtctata aagagcgtgc cggtttctcc ggccagacgc ttcttattaa
     8701 tatggactcc caggccccca accaggctgc ctatgaatgg ctggcaagcg gcggcttcgg
     8761 ctctgtctgt catcttcagc gtgaggttaa attcggaaat tcccgctttg atctttcctt
     8821 tcagaaggac ggaacgctct attttatgga ggtaaagggt gtgacgctgg agcaaaacgg
     8881 aactgccagt ttccctgacg ctcccacgga acgcggcctg aaacatctcc tggagcttca
     8941 ggaggctgcc cgggaaggat acggcgcggc tgtcctcttt gtcatacaga tgaaagatat
     9001 ccgctccttc actcccaacc gtcatacgca ccctgccttt gcagacgcct taaaggaagt
     9061 ttccaaacat ggtgtgcaga ttctggcaaa ggactgtatc gtcacagaac attccatgac
     9121 cattgatcag gacgttccag tcatactcta atccatccac tctttccaca gctgtttaag
     9181 cgctgtagtt taaacagctt tactcctaaa aatcgcaggt aaaacgggca cactgtctcc
     9241 tccgctttca tataaaatag taacgcctat ttttatgatg tgatgatatg ttaaatcctc
     9301 ttagtctgct gacgcccggt cagtcggcag tgatacattg gcttcctgaa cagcctgcta
     9361 tcgtttcacg gcttctggat cttggttttg tccctggagc cgccgtcacc tgcactttaa
     9421 gaagggggaa cggcagtatc tccgccttcc tggtaaggaa tgctgtcatt gctctgcgaa
     9481 aggaagacgc acagctgatt ctggctgagc cgctcccttc ctgctgtgca gaacgtcttc
     9541 ctgaagttca gcaaaacagc agagaatatg acgctttcaa aggaggtgac tctctttgaa
     9601 acagataacg gctgtgcttg caggcaatcc aaacgtagga aagagcactg tttttaacgg
     9661 attaaccggt ctgtcccagc atacaggaaa ctggtctggg aagacggtct cctgcgcaga
     9721 gggaaatttt tctttcggcg aaactgtctg cacaattacc gatcttcctg gcatttactc
     9781 gctgagaact cactctgagg aagaagaaat cgcccgttcc tgcatttgtt ccagccatcc
     9841 ggacgtcctc attgtggtcg gtgacgccac ctgtctggag cggggacttc atcttttaaa
     9901 gcagatctct cagctgcctg atacggagga tactgctatc atgctctgcg tcaatctctg
     9961 cgatgaagca gaaaaacatg gcattctcat tgacttttcc aagctggagg agcttttagg
    10021 cattcctgtg ttccgctgcg ttgccaggga caagaaaaga atcgaagcct tgaaagaaac
    10081 gattgtcctg acctccgcca gagttatctc ccagcccgaa aaggacttca gcccggagga
    10141 aaccgtcagc aaaacagtgc ggtatacaaa aaagaattac agaaaacgcc aggatcaggc
    10201 ggatcgtttc cttaccggac gtttcacagg aagtcttgtg atgattctgc tccttcttct
    10261 gatcttctgg atcacgatta caggggctaa ttatccgtct tcctttctgt gggagcagtt
    10321 tttccgttta gaaacctgga tggccggcgc atttcagacg gcaggctgcc cgcagtggct
    10381 gacagaatcc cttgtattcg gagtttaccg ttctgttgcc tggatcgtat ccgttatgct
    10441 gcctcctatg gctattttct tccccttatt tacccttctg gaggatttgg gatatcttcc
    10501 aagagctgcc ttcaatatgg actgcgcctt taaaaaatgc catgcctgcg gaaagcagtg
    10561 cctaaccatg tgcgtagtct ccgcttctgc ctgaatcttc cctgcttctg cctggacctt
    10621 caatcccctt gatttataaa agcatacgct cttccatcca ttctctaacg cactcttttc
    10681 cattttccaa agaaatttct tttaaaatgg gacaggcatt ttctggcccc gtcatggccg
    10741 tagagggccg cctgacggta gtaatctacc gcctgttcca aatcctgggg aatctgctct
    10801 cccctctcat acagctttcc cagttcgtaa taggcgtctt tatttttctc cttgtttgcc
    10861 gcttccaggt aaagctctgc cgcttttctc tcatcttttt cacagccgta cccgttttga
    10921 tataggaatg ccagcggaag cgcatcctgc aggagcccct tttctctgca ctcctgcaaa
    10981 aagagaaacg ctctgtcata gtcctgcacc actgtttcac cttcaaaata cagccggccc
    11041 agtctttctt tacacatttc gcttccctgg gccgcacctc gctcataata ctccacagcc
    11101 ctgttccagt ctgtttccgg catgccctct gtctgtccct cgtacatctg tcccagcagc
    11161 agacaggctt ccttctgatc tgcccagtga ttgtcctctg acgcgtactc agttaaaagg
    11221 ctctctgcct tctgaagatc cctatgttct ccaggcgcca gacaaaatct ggccagagca
    11281 agtcccgcct ctttttttcc gcagccatag gccctgctgt accagtaata cgccttctcg
    11341 tcatctctga acgtctcttc tgaataaagc tctcccagcc tgagaagcgc ttcccggttc
    11401 tcatgtctgg ccgcttcctc aaaacaggct gctgcctggg aaaaatcctg ttcaattccc
    11461 agtccgttca tgtacagctc tcccagataa aagggagacg tctcgtcgcc ctggcacgac
    11521 gccgcataaa agtaggcaaa cgctgcctca aattcctggc gctccagcgt atacagcccc
    11581 atatgcagca gtccccaggc gtctcctgac gccgctgcct tttcagccca gtaaagcccc
    11641 ctcttttcat tctttaatgt atacgttcct gagaagcaga agcttccagc ctttcgcatt
    11701 gcctttacaa tgccgccctc tccggcctcc tcataccact taaaacagtg tcctgcccat
    11761 ctttcacttt taggaagaat ctcatagaca tcttcataga aaaaggcttc cgctatctga
    11821 taggcggaaa acgcgtctcc ccttttcgca gcctctgcca caagctcaaa actttcgttc
    11881 agagaatacc tggacgcccg tttcattctg tcatcatact gaccagcgcg cgctgctccc
    11941 agcacacagc ggatgcttcc tgcctgtgcc cctgccaaat agtattcata tgccttttta
    12001 tcattaaagc ctacggaacc gtcgccccag ctgcagcagt gtcccagaaa aaacagtgcc
    12061 tctgcatctc ccttttctgc ggcttccttc aaatactcca gtccctgcgg aaaaagagct
    12121 tcgttgcact gcttccaaat cagctctacg cccttttcac acagctctga catcaattct
    12181 gccatatgca ttcctcattt tcgtaacatt tctatggcta tcatactatt tttgaggatc
    12241 ctgtacaact gtttttcaag tttttttata tccatcatcc gctctctgct ctccgcatat
    12301 atatagaaga aatcaaatca cagggtgacg tatatgaacg gtacaatgcc atacagaggc
    12361 gcaatttacc tgcggctgtc taaggatgat gaatccagaa gagagagttc cagcatcagc
    12421 agccaaaggc gccttctgat gagctacgca aaagaacacg atttttcaat tgtcaaagaa
    12481 tattctgacg acggctggtc tggaactacc tttgaccgtc ctgccttcca ggagatgata
    12541 caggatgtca aaaaaggcag cattaatctc attttaacaa aggatctgtc gcgtctggga
    12601 agaaattata tcgtttcagg ccagtatact gaatttttct ttccttctat gaacgtccgc
    12661 tttattgcag tcaacgacgg atacgattct gcggtctctg attctgacat gatcccgttt
    12721 aaaaatatta tgaatgaaat gtatgccaga gatatctcga aaaaaatccg ttcttctctg
    12781 cgtatccgca tgaaagatgg aagctatatt ggaaacttcc ctccatatgg atatgaaaag
    12841 tatccaggac cgcctatccg tttagtccct gatccgaaag cttctcctat tgtaaagcag
    12901 attttcgcgc tgggcgcaga aggcagaact cccgcgcaaa ttgcccggct gttaaacgct
    12961 tcccacatcc tgtctccctc ctgctaccgg atcagcaaat atccgcaatt acgcgaaagc
    13021 agctatccct cctgcggaaa gtggactgcc aatacgatcc tgaaaatgct ccataatccg
    13081 gtgtatttag gccggatggt acaggggaaa agccgaaagc tttcttttaa aagccgcctt
    13141 accatcaaaa atccgaaaga actgtggatt gacggaggta taacccacga agccattgtg
    13201 acggaagagc tctttcaggc atgccaggct gccattgaaa agaggaaatg cagagcaggg
    13261 cagtgaccac tcatggctat gggctttgga tgcaacgcag tgggcgtcac cggctgcaga
    13321 attatcgatt ccccacggga acgcctgatc gccatactta caaactctct cgtcccctgc
    13381 aatggccgct tccctacgtt gatcacgctt tccctgtttt ttatggggtg ctttcaggcc
    13441 tcaaagagcg gcattttctc aattccgccg tctcttgcca cagcccttct cttaacaggc
    13501 ctgattctgc tgggaatagg agccacgctg ctctcttcgc tgattctttc aaaaacgctg
    13561 ctttgcggaa tgccctcctc ctttaccctg gagcttccgc cataccgcag gcctcagctc
    13621 agcaaaatta tcgtgcgctc tgtgctggac cgcaccctgt tcgttctggg ccgcgcgctc
    13681 cttgtagcgg ctccggcagg cctgatcata tggctgtcag ccaatatcca gtggaacggc
    13741 gtaagcctcc tggcccacct gtcaggcttc ttagatccct tcgggcggct gcttggtatg
    13801 gatggaatca tcctgactgg ttttatcctg ggatttccgg ccaatgaaat cgttatcccg
    13861 attattctga tggcctacct gcagaccggc cagctggtgg aaatgtcaga tcaggctcag
    13921 cttttttctc tgctgtccgc ccatggatgg acggcgaaaa cagctgtctg tatggctgtc
    13981 ttttccctgt ttcactggcc ctgctccacc acctgcctga ccatccgtaa agaaactgga
    14041 agctggttct ggacgctgac agccttcctg ctccccactt ttataggcat aagcctgtgc
    14101 tttgcaatga atctccttct ttcataaaac tgactgccac tccttctcac cgcagacact
    14161 tcgctgactg tctgctgtca gtctggccgc attctttcaa aaatatcaga aatgagactg
    14221 cggccagaca gagcccccat ggactgcccg catggttcct gtcttcacgc tttatccgtc
    14281 tttcctcccc catttctccc atacagcccg tccggttctc gccagcagac gaagcaggaa
    14341 caaaagcaga agaaataagc ccagacgaac cgtaattact gtaaggcgtt ttatgacgcg
    14401 tcccgcttcc tccatccatg aaagctctgc cgtttcattc tgcccgtctt ctcttttttt
    14461 ctgatccggc ccggaagctg gctgcttctg cccttccccg tctttcaggc ggtacactgc
    14521 cttcgtcctc cagacctttt tcggagacag aaccacctct cctccgtaaa ctgcctggca
    14581 gtctctcacc agccgttctc ctctggcaca cgcgtcccgg cacagtgctc ctccttcgtc
    14641 ctgataggct tctcccgccc atgcgtagtc agtgattcga taatgtgcct caggaagccc
    14701 cagcatctcc agcaattcgc tctcgtatcc ctgaagttcc gggcggtctg aatctggatc
    14761 tgacgaaatc tcaatccctc ccagctcgta agtatctgcc tgacaggagt gaaacgtgag
    14821 cgtaaaggaa aagtcatcct cccaccgctg gttcccgtac tcgcttcgca ccagaggcac
    14881 tgtaaaaagg ccgttttctc cttccatgga aatctctgct gtctccggaa tttccgcatt
    14941 cattcccacc ttctcataaa cgaccgacga ctccccatac tgcatccgtc caggcagctc
    15001 ctcctctgaa agctcccatg acgccagata ataaggggtg ttctcccgca taaacacagc
    15061 aggcggatcc gcaagctgtg ccggatcatg ctccggctct gaatatttca gaatctccct
    15121 tggcggctgc agctcgtctg cctgcgacaa aaaggccgct gatacagccc acacgcagac
    15181 agcaaataca gtctgaaaca ctctgtataa aacatatcct gctgttgttt tagatcccat
    15241 aattttctcc cttcgtagga ataccagtta cggccgccgc ttatctgcag accagctttt
    15301 gaggaggaac actggcaggc ctttgctgcg ctctgttgtc ttctgtgctt cccgcccaaa
    15361 aggcgaaggc ctgatcattc gttcacttga aatttcgcat gatacctgct atggaaagcg
    15421 cctgactgat gccagcgcct gccgaacatt agaattgtcc tctggaacac tgcggacaga
    15481 tgtggaagat ggcgccaata tacaaggaac tgcaggccct ttgtactctg acgttaggtt
    15541 cagtgtagca aatcgttttg aaaaatcaac tgtttttttc catatattca ttgtcatatt
    15601 tcacaaatct tagtttcatt ttttgtgcat tattttattt tcacgcatgg cagtgtcaat
    15661 ttacaaggga cagctcattg tatctcccta ttcctgccgg ctctggacag aggacagaaa
    15721 aacagccttc cacaatcaat gatcctggaa ggctgtatgt cattgaaata caactggctc
    15781 ctcaataaac tttgttttaa taacaatgaa gggataagat ggagaagctg cctgctggcc
    15841 tccctgttcc ggtccctgaa gctccgtctt tattaccatt gaattctctg tcaggtaaaa
    15901 ctccggaacg gaaatgctga atccccctgt ctgctgttct ccatatccta cggctatgta
    15961 aagatcctct ccgctggtgt aggtcagacg aaattcttct gtttttttct gttcaatcat
    16021 gtccatgagt tccctgggaa tctcattctg ccccaccacg gtaaattcca gatcttttac
    16081 tttctcttcc gcccctttgt cagagcagcc gcccagcaga cagacgcagg acagcagaag
    16141 ccccgccgcc cagacagcca gttttttcat gttccccata tgcttcacaa acgctcccgg
    16201 ttctatttgc tattatttta ttaggaagct gtctgtttta ttcctctgct ggttacagaa
    16261 attttttatc ggcgctgcag gcctgaagct gatgctgata cttctctttt gtagccagtc
    16321 ccccgcggat gtggcgttct gccttgttaa tgttcaggac aactctcgcc tgggccgcta
    16381 aggatgggtt gatatcttcc aggcggtcag tgacatcctt atgcaccgta ctcttgctga
    16441 ttccaaactt cttcgccgtc tgacgcaccg tagcgttatg gtctatgatg taattggcga
    16501 tttccactgc ccgttcctca atatattctt tcatgggatt acccctgaaa atgtttttta
    16561 caatttatgt ttccatatga aaaaatatgc cggtttccct cagcttctcc tctggacaaa
    16621 cttgtttttt atggtaaact taatatggtt ttgccgccag ttcagactgg ccaaaaccgc
    16681 aggaaacaca cgaagaaatc cgccgaaaca tcatccagaa cggcggaaaa gggggatgta
    16741 tgaaacgtga aatgaacgct gacgtgtcga atatttacca gctggagggg caggtccctg
    16801 ttatgaaggc gatcccgttc ggtcttcagc acattctggc catgtttgta tcgaacttaa
    16861 caccgattac cattattgcg gcagccggag gactggctca ggcggaaatt gcagttcttc
    16921 tgcagaacgc catgtttgtg gcgggcatcg ccaccttaat tcagctctat cccatctgga
    16981 aaatcggctc cggccttccg attgtaatgg gagtcagctt tacctttgta acggtgctca
    17041 gcactgtggc ggccaattac ggctatccgt ccgtcatcgg agccgtcctg gtgggcggta
    17101 ttctggaggg gactctggga cttctggcca aatactggaa aaaaataatc gctcccattg
    17161 tatcggcctc tgtggtgacg tccatcgggt attctctctt caccgtaggc gccagatcct
    17221 ttggcggcgg ctatgcggaa gatttcggct ctgctgaaaa ccttctgctg ggtaccatta
    17281 cccttctggt ctgcctgatc tggaacatta aggccaaagg gtaccgcagg cagctctccg
    17341 tactggccgg cctgattgca ggctatgctg ccgccatttt tatgggaaag gtggatttct
    17401 ccgttatttt ttcaagcgga ttgatttctc tgccaaaatt ctttccctac atgccggaat
    17461 ttcatcccgg agcgattttc tctgtggcga ttattttctt tgtatcggct gccgagacca
    17521 ttggagacac cacggctatg gcttccagcg gcttaaaccg cgccattaca gagagggaaa
    17581 ttacaggttc tctggcctgc gacggatatg cgtcggcctt ttcctccttc ttaggatgtc
    17641 cgcctgtcac ctccttttct caaaatgtgg ggctgattgc catgacgaag gtggtaaacc
    17701 ggttcaccat tatgacaggg gccgcctgta tgcttctggc cggactgctt cctcctgttg
    17761 gaaacttttt tgcttctctc cctgaatcgg ttctgggcgg atgcaccatt atgatgttcg
    17821 gcaccatcct cacctcaggc attgagatgc tgtcaaaggc cggctttact cagagaaata
    17881 tcaccatcgc ggcgctgtct ctctcaatcg gaatcggctt taccactgcc agcgaaacag
    17941 agatctggca cattttcccg gacatcgtcc agtccgtttt ctccgctaat gtggtggcag
    18001 tagtatttgt cgtatccatc cttctgaatc tgattctgcc ggaggatatg gaaatgaaac
    18061 attctgccat gtaaatctgg ccagagggcc acagagggcc gctggggaag actgaatcca
    18121 gtcttttccg gcggcttcgt ttatttttga tactattttt attttcctct cctctttctt
    18181 tttatattgt gttttatttt gaaacaatat ctgccgcgtt tttcttcctt ttctcccttc
    18241 aattattatt tagttcaaaa acgaaacaat tttattgttt ttttcgatgc caaatccgtt
    18301 taaatacggc ataatatata atatcaatac aagaaaagag gaagaattat gatccttctt
    18361 ttaattatcg cggacgactt caccggagcg ctggacactg gcgttcagtt cgccgcccac
    18421 ggcgtttcaa cccgggtgat tgtagatcct gaggtggact tttccgctta ccatgacagc
    18481 gttttagtga tagacacaga aacccgccac ctcgcggccg gggaagcctt cgatatcgtt
    18541 gcccggctca ccagaaaagc cagggaggca ggaatccgct atatttacaa aaagacagat
    18601 tccgctctca gaggaaacat aggagccgag cttgcagcgg ttctcactgc cagcggctgt
    18661 aaaagccttc cgttccttcc ggcgtttccc cagactggac gagtcaccag agagggtgtt
    18721 cactatgtgg acggcgttcc cgtgacagaa agcccctttg ggatcgaccc gtttgaaccg
    18781 gtggttcatt ccgttgtcac agaattaatt ggcgagcagt gccagcttcc ggcattcagc
    18841 tttccggctc tgtccgaagc ttcacaagcg cccagtcagg aaggaattct ggtgttcgac
    18901 gcgtccacgc cttccgatct tctggaaaca ggaaaaaagc tggctgaggc agacatgctc
    18961 tccatcatgg ccggctgcgc cggcttcgga gccgttctgc ctgaactgct ggacattgcc
    19021 ccagacaggc tggccgctct cccaaagctg gatccgagac ttctggttgt ctgcggaagc
    19081 gtcaattcca tcaccctggc gcagctggat cgggcagaaa aagctggatt ttccaggctc
    19141 cgcctgagcc cggaacagaa gctggaaccg ggatactggc agacagagcg gggaaaagag
    19201 gcgcttcagg gcatcgagga catgctggcc tcccactctc actgcattat cgagagcaac
    19261 gatttgggcg gaaaccagcc caccgccgac tatgccgcag cccttggcat tgaccgggaa
    19321 actctgagag tccggatctc cggctgtctc ggctacctgg tgggagaaat ctttacaagc
    19381 ccctctctgg gaactctgct tctcaccggc ggcgacacgc tgcttcagtg tatgaactgc
    19441 gtcggagtaa acgaactgga acccctgtgc gagctggatc gcggcgtcgt actggcccgc
    19501 ttcacctaca acggctgcac ccgccatgtg atcacaaaat ccggcggttt cggccaggaa
    19561 actctgctga ccaatctggc agaacagatt gctgattaat ctttacattt tattttaaat
    19621 attacatatt ggaggaaaac attatgacat atccgaaact tcccggactg acctgggatg
    19681 gaaccattta cgaaaacgaa gagatgggaa cctgtgaagc cctgcttccc acaggcggtt
    19741 atcccaccgc tcacgctccc gccatggcgg aacttccaaa cggcgatctg ctgtgctgct
    19801 ggtttgccgg aacctacgag ggaagcgctg atatccatgt catctgctcc ctccttccga
    19861 aggacgctcc cgcatggctt ccgccggtag aggtttccgg agatccagag cgcagcgagc
    19921 agaatccttc cttattttat ggacctgaca atgccgtatg ggccatgtac accgcccagt
    19981 tagaccgcca ggagggcaag gacaatatgc agtttacctc tgtggtccgc tgccagaaga
    20041 gcacagacgg cggaaagaca tggggacctt acgagaccat cttcccggag gagggcacct
    20101 tctgccgcca gccgatccag gtactttcaa acggacgctg gatcttctcc aactggatct
    20161 gcaccgactc tgcagacggc ctttccggcg acccgactgc cttccgcatt tccgatgacc
    20221 agggaaagac ctggaaaaag gtgatgatgc ctgagagcaa cggccacgtt cacgccaatg
    20281 tggtagaatt agaaccggga catctggccg catttatgag aaaccgcgag gcataccgca
    20341 ttcacagaag cgagtccttt gactggggcg agacatggac caagccggag ccgactcccc
    20401 ttccaaacaa caactccagc atcagcgccg ttaagcttca gagcggacgc atcgccattg
    20461 cctacaaccc gacctgcact ccggatccgc agccgggaaa ggccgcatgg ccgggacttc
    20521 gctgcccggt ggcagtggct ctctccgagg acggcggttt aaccttccca atcatccgct
    20581 ggatggagag aggcgagggc ttcatcggag acgaaaataa gacaaacaac aagcagtacg
    20641 aatatccgta cctgatgcag acgcgcgacg gcatgcttca cctggcctac gccgcccgca
    20701 cccgtcaggg cgtaaaatac gtccgcttca gcgagcagga cgtgctgggc gagaagagag
    20761 agcgcgtagg actttacaac cccaccgccg ctcagagccg ttaatcttta tacacgaaac
    20821 cattcaagga ggtttttaaa tatgcttact acttacaacc tgaaaatgcc tcacgccgtt
    20881 tacggcggtg agaacgctat ggacaacatt acttctattt taaaatccaa cggcgtaaag
    20941 cgcgtagcta tgtttactga taagggaatc gaggaggccg gtcttttcgc ccttcccgag
    21001 gaagctgtca aagcggcagg cgcagaatat tatgtgctgg acgatcttcc agctgagcca
    21061 agctacatgg ctgttcagaa gctggtggac gaattcaagg ccagcaaagc tgacatgatt
    21121 gtggcctgcg gcggcggaag cgttatggac gcagctaaat tagccagcat tctggttaca
    21181 gacgagtacg gcgtcaagga gctcttagac gatccgggcc gcgctaaaaa gtgcgttccg
    21241 attatcctga ttcctaccac tgccggaacc ggcgcagagg taactcccaa cgccatcgta
    21301 gccgttcctg agaaagaatt aaaggtgggc attgtcaatg aaaacatgat tgccgactac
    21361 gtgattctgg atgcccgcat gattaaaaac cttccgcgca agatcgcggc agctaccgga
    21421 gtagacgccc tggctcactg catcgagtgc ttcaccagca acaaagccaa tccgttcagc
    21481 gacctttacg ctttagaagg ccttgacctg attctcaaca acatcgagaa ggcctgcgac
    21541 gatccggagg ccatgacaga gaagaaccgt atgcagatcg cagcctacta cggcggtctg
    21601 gctatcacag ccagcggaac cacagcagtt cacgccctca gctacccctt aggcggcaag
    21661 taccacattg cccacggcgt ttccaacgcg atcctcttag ctccggttat gcgtttcaat
    21721 gagccggcct gccaggagcg cttcgctatt gcctacgacc gctgctgcca tgacgaggta
    21781 aagacctgca ggacaaacgc cgagaagtcc gcatggatca tcagccgtct ggaggagatt
    21841 gtaaagcacc tggacattcc taccagctta aaggagttcg gcgttcctga ggaggatctg
    21901 gacggcctgg tagaagccgg aatgcaggta cagcgtctcc ttgtaaataa cccgcgccag
    21961 gtaacgcctg aggatgcgag aaagctctat ctggagattt tatagggcgc tgtttcgaaa
    22021 ccaaaaatca ttttataatt tacataacac aggaggaatt cactatgaaa ccagttgaaa
    22081 tcaaaggtat tatcccgcca attctcacac ctatgaacga cgacgagagc atcaacgtag
    22141 cagagctccg caaccaggta gaccgtatga tcgagggcgg cgttcacgct ctcttcccat
    22201 tcggaacaaa cggcgagggc tacatcctga acgctaagga aaaacagctt gtattagaga
    22261 ctgttattga gcagtgtaac ggacgtgttc cggtatacgc aggaaccggc tgcatctcca
    22321 ccaaggaaac catcgagcag agcaagatgg ctcaggctgc aggcgcagac gtactctcca
    22381 tcatcacacc aagcttcgct gctgccagcc aggacgagct ctacgctcac tacaaggccg
    22441 ttgcagaggc agttgacatg cctatcgttc tctacaacat ccctgcacgt acaggaaacg
    22501 ctctggctcc ggctactgta gcccgcctgg ctcagatcga gaatatcgta ggcgctaagg
    22561 attccagcgg aaacttcaca aatattttag gatacattga cgcaggcgcc aagaagacaa
    22621 acggcaagtt ctgcacactg tccggaaacg accagttaat catctggact cttctggcag
    22681 gcggtacagg cggaatcgca ggctgcgcaa acgtatatcc gcacaccatg gcttccatct
    22741 acaacctgtt catggagggc aagatcgagg aggccaaggc tgccaatgca agcattcaga
    22801 gcttccgcgc atgcttcaag tacggcaacc cgaacactat cgttaagact gccactcgtc
    22861 tcttaggcta caacgtagga ccgtgccgtg ctccgttcaa ccaggttccg gaagagggta
    22921 tccaggcatt aaagaaggtt ctggctgaaa acgaagctaa gggtatgcgc taattaaggg
    22981 gggtacgact atgaacgcaa agccgattgt cggtattact atgggtgatc ctgccggaaa
    23041 cggccctgag atcaccgtca aggctctggc tcacgccgag gtctatgaca gctgccgccc
    23101 catcgttgtg ggcgatgtaa agatcatcga acaggcggcc cgtttcgtag gccgtcccga
    23161 tattacaatt caccgctgtg agaaggtaag cgacgccagg ttccagcagg gcgtcatcga
    23221 cgtgctgcac ctggaactga ttcccgatgt ggagaaattc cccattggac aggtcagcat
    23281 tgaaggcgga aacgctgcgt tccaatgcgt aaaaaaggtg attgagctgg ctttagccgg
    23341 agaggtagac gccacctgca ccaacgctct gaacaaggag gccatgaaca aggctctgga
    23401 gttctatcac ggagagaatt ccgacggcta cactcatttt gacggccaca cagaaattta
    23461 cgccacttac acaaatacaa aaaaatatac catgatgtta gcccaccacg acctgagagt
    23521 ggttcacgtt tccacccacg tctccctcag ggaggcctgc gaccgggtaa agaaggcccg
    23581 cgttctggag gtaatcgaaa tcgcccacaa ggcgtgcaaa gatatgggaa tcgagaaccc
    23641 gaaggtagcc gtagccggtc tgaatcccca ctgcggtgag aacggcctct tcggcacaga
    23701 ggagatcgag gagattaagc ctgccatcga ggcggcaaag gcagaaggca tcaacgccat
    23761 cggccccatt ccgccagaca gcgtcttctc cgaggctctg ggcggctggt acgacatcgt
    23821 ggtgtgcatg taccacgatc agggacatat cccgctgaag acagtgggct ttgtctatga
    23881 cagggagctg caggcctgga aggccgtaga gggtgtcaac gtaacgctgg gccttccgat
    23941 catccgcacc agcgtggatc acggcacagg cttcgccctg gccggaaaag gcaccagcaa
    24001 cgagttaagc cttgtcaatg ccatcgacta tgcagtccgc atggcaaagg gaagaaacta
    24061 accgcataat cacttgccta aggagggcgg agcgcaggct ccgctctctt ttttatcatt
    24121 tccgctaatt tttcagaaga gaagaaaacc tttcccctct tcactatatg ttctaaaatg
    24181 aaacccattc tttcctatct acctttattg ttccatttat aaacagtttt tcattttcta
    24241 tttatatttt tttaatattt gttcataaat gaaacataat cagaggttga ttttattgtc
    24301 ttctctctca gcatcttata taattaatgc aaatgaaagc cataccagat tgtgcagatt
    24361 gcagaactga ctgcattggg tatgaggcta ctataagata tgaggaggaa aaacatatga
    24421 ccacccaaat gattattgct ttagcaatca cagcgctcat ggtcgttctg atcatgatgg
    24481 acaagctgcc atttggcgcg ccgcctctgt tagcctgtct tctgctcgtt attttcggaa
    24541 tagcagatat caaggcagcc ttcggcggat tctctaacgc aaccatcgtt atgcttgccg
    24601 agttcatggc aatcatcgca gctcttcaga aaacaagctt tatcgctaat ttcaagaaga
    24661 ccatgtttaa gatcgccaac cagggcggaa tcaaggctta catgctgatg attctcatcg
    24721 ttatgttagg ctgcagcctg ttcggaaccg gttccaccgc ttactacgtt atggttatcg
    24781 gcttcctgtc tacactgccc tacacaaaga agcttccgcc gtccaaggtt gttatgacag
    24841 ccggcttcgc tgcgaaccat ccgttaattc cgttcaacac agcgctgcag tacggtatcg
    24901 taatcgcagt attaaacagc gccggcattg cagcgaacat accggtttcc aagtttgcca
    24961 ttgtaaacct gttcctgtcc ttaggcttcc tgcttaactg tgtgattcag tataagtttc
    25021 tgccggatca tccgattgca gcttccactg acgcagcagt ttccgaggac gcagctcctt
    25081 cccttccaaa gtggaaagag caggttacat acttcgtatt catcctggct gtagtcggta
    25141 tgcttcttca gagcaaaatc ggcgacgcag gctacgctat cgcaggtatc tctgttggcg
    25201 taatccttgt aacaggcgtt atggatttca aggaaatccg cgattctatc agtgctccta
    25261 tcatcctgat gtccgccggt gttatcggtg tggctgacgc tcttggaagc acaggactga
    25321 cagacctggt aggttccact gtagctaata tgctgggaac aaacgtaaac ccattcgtta
    25381 tgattttcgt tttctgtatc ctcacaagtg tgcttgctac actgacagga tctacaatcg
    25441 gaactgttta cgtattcgct cctcttgcca tcgctacctg cacaagcctt ggacttgatc
    25501 cgactgcagc agcatgtgca atcgtaatct ccggatggtg cggacacttc cttcctatcg
    25561 acggtatgcc ggccatggtt atgggcgtcg gaaactacag cagtaaggaa ttctgtaagt
    25621 tcaccattcc gcagtacttc atccgtctgc tggcattaac agcaggagcc ctgttagtat
    25681 tcccgatgta atcgcttcgg gcctgtaaaa gaaagaggta cagttatgaa gaataaattt
    25741 gaattagagc acgttggcat caatactccg aatccagagg aggctgagaa gttagcccag
    25801 ctgttaagcc tggtattcaa cctggaacct cgccacggac agaaatccga gttcgctggg
    25861 ccatactttg agtgcatgaa ggctccattc ctgggaacga acggccacat tgccatgcgc
    25921 actcctgatt taacagctgc cgctgaggag ctgaaggaaa aaggctttga cctcaacatg
    25981 gacacagccg cttacacaga agacggaaaa ttaaagaacg tctatctggc aggagaattc
    26041 ggcggctttg ctatccacat tatgcagaaa taattctttt atttgttaat gaacctttcc
    26101 aagaaaaaca gaacccggtc tctggcatct tccagaaacc gggttctgtt tttctttttc
    26161 ttctctttta cgcctgctct tcgattggaa gctctgctgt aaagacgctt ccctccccgt
    26221 acacgctctc cgcccggata cttcccccgt ggactctggc aatccacgct gccatggaaa
    26281 gtcctaatcc tgttccctcg gagcttcggg aacgatcggc ccggtaaaac cggctaaata
    26341 tctgtcccag gtcttccctc ctgattccaa ttcccgtatc acgcaccgtc aaaacagcgt
    26401 attttcctct ttttctcagg gaaacctccg cgctgccgcc cgggcggttg tagcggatgg
    26461 cgttggacac cagattattg accatgcgga tgagaagcgt ctcgtctccc gttatctgaa
    26521 gctcctccgt gttccaggtc agctccacct gacgctctgc ggccatggcc tcaagctcct
    26581 cgcagacggt ctcgcatagt acgttcagtt ctacaggttc cctctccggc acaaattttc
    26641 cattttccgc ccggctcaga agaaggagct gggatacgat ggagttcatc ctctcagact
    26701 gctttaaaac ggcttcaaac gcttctctct tttcctcttc ccccgcctgc ccggaaaggg
    26761 cgaactcgca ctgagaacgg atcactgcaa tcggcgtgcg aagttcatgg gacacgtcgg
    26821 aagagaactg cctctccgcc tcgaaagagg cctgaagacg ggccagcatc tcgttcatgg
    26881 tatctcccag ctggttcagc tcatctcccc gtccgtctgt ctcgattctc tggctcaaat
    26941 cgctgccggt tccaatggct ctggccgtct ctgccatctg cgttaccggc cggaacgccc
    27001 gcctggtaat ccggaagccg ccgagagccg ccagaaccgc cagaagaggc agcgcagatc
    27061 cgaaaagaat cggcagatta cccagggcct gcccgtactc tgtcatggaa atcatgcctc
    27121 tcacccagaa tccggcgtct tccccttccg aatacacatc gtagatcatc caccgctccc
    27181 tgccgctgga ggccgtctta atggtctgat cctccagcag agaatccacc tgaatccccc
    27241 ttgtcacctt aggagccaga aggcgcccct gtgtgtcata gagaaagaca gaaactccgt
    27301 tcttgtagaa atccagttcc tccgcgtcca gctctccgta tctgaaacgg acctgtgaaa
    27361 ccgcgtctgt caccgtatcc accagccgct cccgcatctg cctgcctgac atacgctggg
    27421 aagaggagac aaggtatact gccgtaattc caaatacgag aatcatgaag aaggtatacc
    27481 agagcgtgac tctggccttg atggaaagtc ctttatgcct tttcttcatg gactattcct
    27541 cccgcagcgt gtacccggct ccccggatgg tgtggatgag ttttttctca aagggatcat
    27601 ccagcttttt cctgagatac cggatataga catccacaat attgctgccg ccctcaaacc
    27661 cgtaatccca gacctgattt tccagctgtg tcctggacag cacagctccc ttgtggcgga
    27721 ttagggactc taacagcgcg aattccttcg aggaaagatt aatctccttc cctccgcgaa
    27781 tcactcttct ggtggaaaat tccactgtca gatctcccac agagacagcg tctgtctttt
    27841 ccggcgaacg cctcctcaaa agcgcccgga tccgggctgc cagctcctca aattcaaacg
    27901 gcttggtcag gtaatcgtcc gcccctgcgt ccaggccgcc cacccggtcc cctaccgaat
    27961 ctctggctgt cagaagcaga accggaatct ggcttccccg gcttctcaaa gtcctaagca
    28021 cggtgagacc gtccatgttc ggcatcataa tgtcaagaat cgccacatca tactctgtat
    28081 gctccaggta gtagagagcc tcctccccgt ccgggcatcc gtccgctccg aatccagccg
    28141 ccctgagccg ctttatcgta atttcccgaa gatccggctc gtcctccgca aataaaattc
    28201 tcatatggtt tctcctcgtc ttttccttgc attttttctt ctatttatgt atcatttcta
    28261 atgtattttt aattttaccc ccgtaaacta tagttatcaa caaaaaagag gaaaaacggt
    28321 gcagaaagaa agctttccct gttccactca aagccactgg aaatttttct tccgcttatt
    28381 ttcttgttta aaaggaggat tttgtatgaa acgaaatgac aatccatatg ataaaatgct
    28441 caacaccgcc ggcagggccg ctaaagctgc ggcttcgggc cttctcctgg ctcttcttct
    28501 ggctggctgc tctcagaaaa accctgtcaa aacccagcct atttcctcta tggaaagcag
    28561 ctcagaggcg ctgggagaaa cttctcagac agctgcggct tccgagatct ctccgtccgc
    28621 ctctggcacg gcgggaagca tagaaacgga cgctgaaagc tactaccgcg cgaaggccga
    28681 gcaggacgcc atccacattg atattgcgaa gctggaagcg gacttccggg tggggaaact
    28741 gtcaaaagaa gactttgccg ctcaaaaatc ccagctggaa gcagagaaag acgccctgga
    28801 tcgagaggag gatcgcctgg aagacagcct ggatctggcc tacagccaga gcagccccgc
    28861 tctcccgtca ggaagtctgg aagagctgcg ctctatggcg tctgagctgg agcaaaagga
    28921 acatcagctg gaagcccagg aggacgctct ggagcagagc tactggtctg gagacgtggc
    28981 gagagacgag ttcatcgctc agcagattga gctcatccga accgaagaaa ccatggatcg
    29041 ggaggcagat ctgctggagg acgccctgga agctatgggg tttgacgatt aagacgtttc
    29101 ttctctgccg ccagcgcccg catttcccgg gcgttctggc gcaccgcctc cgtaatttcc
    29161 gcaccgccca gaagccttgc cagttcgtct gtcatctgat cctctgacag ccgcttaatc
    29221 tgtgtcacag ttctgttttc cttcgcagtc tttcgtatct catagtggct gtcggccata
    29281 gccgcaatct ggggcaggtg ggtgatgcag atgacctggt ggcttcctgc gatgaggctc
    29341 agcttctcag acaccatctg cgccgtccgg ccgctgattc ccgtatcaat ctcgtcgaat
    29401 atcagcgtgg gaatatcgtc cgtctccgcc agaacagcct tgatggccag catgatcctg
    29461 gacagctcgc ctccggaggc cacagctccc agaggacgcg gcggctcgcc cgggttcgtg
    29521 gaaatcaaaa attccgcctc gtcaaatccg ccagccgtat agtgggaaag acggcggaat
    29581 tccatggtaa actccacgtt caggaaattt aagtcagaaa gcccctctct catcctctct
    29641 gtcagcgtct gcgccgtctc ccggcggatt tttgacagtt ccccgcagag agtctccaag
    29701 cgctcttcca gctgggcaaa gcggcgttct gtctcctctc ttctcaggtc aaagtgttcc
    29761 agctcctcca gcttttctct cttcttatcc agactgtcca gcaccttctc tatggtgtcg
    29821 ccgtatttat tttccagtcc ccggatcagg tcaaggcgct cctccgtctc tcggaaggcc
    29881 gcctcgtcga aggtcatctc ctccatgtag gaagaaattt cccggtttaa atcgctcatc
    29941 agagcgtcca catcgtagag ctgatcccgg attccggaaa tcccttcatc gtactcagcc
    30001 gccttctcca cagccagaag cgctctcgcc acagcgtccc cgttgaccgc ctgataggcc
    30061 tcggacaggc tttccacaat ccttctgcta ttggaaaaac ggcggtacgc gctctccagc
    30121 tcctcctcct cgccaggctt taaaccggcg ttctcaatct cctcgatctc aaaacgcaga
    30181 aaatccgtct ccctcagaag ctgctccctg ccgctctggt aatactccag cttctttttc
    30241 acagccgcgt actcctggta ggcttctgct gtctgttctt ttaatttggc aattctggat
    30301 tttccatact cgtcgagaat ttcgagatgc ttggcgtgat agagaaggga ctgatgttca
    30361 tgctgtccgt gaatatcaat gagaatgccc gtgatttccc gaagcctggc ggctgtcacc
    30421 gtctcgtcgt tgatgcggct gatgcttctg gaaggcatga ttttctttga tatgataaga
    30481 tttccgtctg catccgggca gacctctctg gcggccagtt cccgccgttt tttttcatct
    30541 gtgacggaaa acaccagttc tacataggca taatcgcagc cctggcggat catgtccttc
    30601 gacgtttttc cgcccagcgc tgcgttgaca gaaccgatga taaccgactt tcctgctcct
    30661 gtctctcctg tcaggatatt gagcccctcc tcaaattcca cctcagcgga atcgatcaga
    30721 gccagatttc tgacgctcag atgaaacagc atggtatcac ctctttctat tatgacagtc
    30781 cgtgttccgg acctttttaa tgattgacta tcttctttaa tttatccatc agaaggatgg
    30841 tgtcgtccac cgttctgaca gcacacataa tggtgtcgtc tcctgcgatg cagcccacca
    30901 cctcgctgaa atggatggcg tccagagcgg ccgctaccgc catggccatg cccgccacgg
    30961 tcttaatgac cagaatattc tgggccatgt ccatggagag aaagccgtcc ctcagaatgc
    31021 ggatatactt gtcgttaaag gccgtctgct gcggatggaa caccgcgtac ttctgccgtc
    31081 cgtgctctcc ctggatcttg gagagcttca gctccctgat atccctggac accgtggcct
    31141 gcgtcacgtt gtagccctcc ttattcaggt actctgccag ctcctcctga gtctcaatgt
    31201 tgtattttcc aatcagctcc acaattttgc tgtgacgttc cagtttcatg tgttatctcc
    31261 ccttcttttc atctgcctta aatctgcttc atccgatctc tcagattttc taaaaacgat
    31321 acctttttca ggcggatcag cgtagtcacg gtctccgacc gttcaatccg caccaggtct
    31381 ccatttttta aattcacctg ggtatctccg tcaaaactca aaaactttcc cgtctccccc
    31441 cggcctgtaa tttccagctc gatcacccgg tccggcgcca gcaccacgct tctggaattc
    31501 agggtgtgcg ggcagatagg cgtcagcagg atcatctctg aatccggcac cgcgataggg
    31561 ccgcctgccg acaggttgta ggccgtagag cctgtgggcg tggccgcaat gattccatcc
    31621 gccgaataat cgtttaaaaa ctctccgtca atggaaaggt tgaaccggag catgttaagc
    31681 cccattctgg agaggacaat atcgttcagg gcaatgtctt cagctatcac cctcccgtct
    31741 gaaatcacag ttccttttaa cataattctc tgctccagac cgtaatggtc tgcaatcagc
    31801 tcgtccaagg cgggaagaat atcctcctcc cgtcctatct gggccagata gccgagcgtt
    31861 cccatattga ctcccaacag cggaatattg cttcccgcta ggtctctggc agcctggatc
    31921 agagttccgt ctccccccag cacaatcgcg cactcaatcc agcctggaac cgcctccctg
    31981 tccgtatacc ggaactgtag tctgcgggat ctgcaggcgt ctgtatcgct ggcatcccac
    32041 accacgcact cacagcccct gccctccaag tagtcccgga tcagttctgc cccatattct
    32101 gcctttttct ttgagtggtt gacaatcata taaaaatatt tcatctcacc tgctccgcct
    32161 tccccgcctc ttcctttccg ggccttttgg cctctgcgtt tctgctattt atccagctct
    32221 ctgtgagccg cctccaccac gtccttcggg ctgacggaaa gctcctcctc cccgccgctg
    32281 ccgttattct gcagatggag gagatattca atatttccct ccggcccctt aatcggagaa
    32341 tattccaggt tcaaaatctg gaaaccgatg gcctttgcaa aggaaatcac cgtctcaatc
    32401 acctctaaat gagtactctt ctcccggact acgccctttt ttcccacctt ttcacggcca
    32461 gcctcaaact gcggcttaat caggcacaca atctggccgt cctctgtgag aagctccttc
    32521 acaggcccca gcactttggt cagagagata aaggacacgt caatggagga aaactccacc
    32581 gggtctccga tatcgtcagg cgtcacatag cggatattcg tcttctccat gcagactacc
    32641 cggggatcat ttctcagctt ccaggccagc tgtccgtggc ccacgtccac ggaatacacc
    32701 ttcaccgccc cgttctggag catacagtcc gtaaagcccc ctgtggaagc tcctacatcc
    32761 atgcagacct ttccgttcag ctccacgccg aaatgagtca tggctttctc taatttcagg
    32821 ccgccccggc tcacgtattt taaaacggct cctctgacct ccactctggc cttctcgtca
    32881 aaggtggtgc cggccttgtc ctccttctgg ccgtccacgt agacgattcc ggacataata
    32941 atggcctttg ccttttctct cgactctgcc agcccatgtt tcaccagcag aacgtccaga
    33001 cgttccttca tctgcgtcct ccttataaaa aatgctcttt tatcttcttt aaaatggaat
    33061 cgctgtcaat gcccagatca cttctgagaa gcgacacgtt tccgtgctcc acataagcgt
    33121 ccggaagagc gatattcaac accttaagct ccggatagcg cttcgcggca taatcggtaa
    33181 tccgctctcc gtatccgccc cgcagcacgt tttcctccag cgtcactatc accctgtgat
    33241 tcttagccag ccggtccact atatccgtat ccacaggctt aataaaccgc ccgttgacca
    33301 gggtgcagga cactcccata tttttcagct tcaggcgcac gtgctctgcc gtgctgacca
    33361 tgcttcccac ggccagaaga gcgatttcag actcttcaaa cagcatctcg ctcttcccgt
    33421 actcaatggg agccagcgcc tctttcagtc cccggtaggc ctgtcctctg ggatagcgga
    33481 tcgccatagg gccgtcgtag ttcacgccga accgaatcat ttcccgaagc tcccacagat
    33541 ttttcggagc catcacgctc atattgggga tggatgacag aaagctcagg tcaaaaatgc
    33601 cctggtgcgt ttccccgtcg cttcccacca gaccggcccg gtccacacag aacagcaccg
    33661 gcaggttctg aatacagacg tcgtgaagaa tctggtcgta ggctctctga agaaaggacg
    33721 aatacaccgc caccaccggc ctgagccccg ccgccgccat tccggcagct gaggtcaccg
    33781 catgctcctc ggcaattccc acatcaaaga accgctccgg atagagcttt tcaaacctgg
    33841 aaagccctgt tcctcccggc atggccgccg tgacggcggc cacccgcttg tccttctccg
    33901 caatctggca gatagtcttt gaaaatatgt ctgtgtagct gggataaatc ttcgccgcca
    33961 ggggctttcc cgtctccatg tcaaagggct ccaccccgtg gaaggccgac gggttcttct
    34021 ccgccggctc ataccccttg ccctttttcg tcagcacatg gataagaacc gcgtgatcca
    34081 tctttttcgc ttctttgaaa atacgaacca gctgtctgac attgtgtccg tctaccgggc
    34141 cgatgtaggt cactcccatg ttttcaaacc acatgcctgg gataagcagc tgcttgatgc
    34201 cgtttttcgt cctggtcagc gtctgaacca tgctgtttcc cactctgggg atacttcgaa
    34261 gagccgccac cacagacttt ttcagctcat tgtacccctc gtctgccctc agattgctca
    34321 gatagctgga aatgcctccc acattcttgg agatggacat gttgttgtca ttgagcacaa
    34381 taataaaatt cttcttaatc tgggccgcgt tgttcagagc ctcgtaggcc atgccgccgg
    34441 tcagggcgcc gtctccgatg acggaaatca ccgagtaatc gtcgcccctc acgtcccttc
    34501 ccagagccat gcccagtccc gctgaaatag acgtggaact gtggcctgtg tcaaaggcgt
    34561 cgaaggggct ctccttccgc ttgggaaatc cactgagccc tccgtactgg cgcaggccgt
    34621 cgaaattttc tttccgtccg cttaaaatct tatgggtgta ggactgatgt cccacgtccc
    34681 agataatctt atccttgggc aggtcaaagg cgagaaacag agccattgtc agctccacca
    34741 cgccgagatt ggacgccaaa tgtcctcctg tgcggctgat cttctcaatc agaaagctgc
    34801 ggatttcctc cgccagaacc gcaagctccc cgtccttcag ctttttaatg tcgtccggcc
    34861 cattgattct ttccaaaatc acggcttcac cttctctccc attatttttc cctgtgtatc
    34921 aggaggcgaa tcagcgcttc caggaactcg ttccggccgg gaaggccagc cagaagcttt
    34981 aacgcgtcgt ctgacagcct ctccacctcc gctttcgcct tctccattcc ctccagcgtc
    35041 acataagtgg ttttattgtt cttctcatcg cttcctaccg gctttcccaa aacctcctgg
    35101 ctgctggtca catccagaat atcgtcctga atctggaagg ccagtcccac gttcgcggcg
    35161 attctctcca ccgtttgaag ctcctctttg gacgctccgg ctagtaccgc tccaatcatc
    35221 atggaggcct ctaacagggc gcctgtcttc agctggtaga taaaatccag ctgttccctg
    35281 gaaaccggct gattagtcag ctccacatcc accgtctggc ctccaatcat gccgtaaatt
    35341 cctgtttttt cggccagaat gccaatgcac cgtcccaccc ggtctgcatg ggccgtcatg
    35401 gcaaaggcgc ggctggccgt ctcaatggca tagattaaaa gagcgtcccc ggacagcacc
    35461 gccatatcgt agccatacgc tacccaggtc gtctttctgc ctctccggta ctcgtcgttg
    35521 tccatacagg gaagatcgtc gtgaatcagg gaggaagtgt gaatcatctc aatggccgcc
    35581 ataaagggct ctatttcctt ccctgttccg ccaaatagcc ggtaaacctc ccgcatcagc
    35641 agagggcgca gccgcttccc gccagccttc acactgtaat tcatcgcctc gaaaatcgtc
    35701 ttctggtgtc cctcttcctt cgggagaaag gagtacacca cgtcctccgt ctcctttgta
    35761 tactgtaaaa gctgttctct aagctccata gtctcctccc atctcgtcga tcaccagaat
    35821 ctgcttttcc acccggtcaa tctttcctga gcaggccttt accagccgca ttccctcttc
    35881 atagtaccga aacgaatcct ccagagagct gctgccgtcc tccaggcctc ctatcacctg
    35941 gttcagccgc tcaaacagct cctcaatgga gcaggcctct aattcctcct ggttcggttc
    36001 tggcagacgt cccttctctt ccatgacttt ttcctctctt ctctattctc catggcagtc
    36061 ccggcggctg tagggaaaca cagcttccac tctggcgtca atccgcccgt ccgccgtcct
    36121 gacctcaatc ttctctccag gcattacctt atttacagaa tctaccctct ttccagtctc
    36181 atccgtcaca aagccaaagc cctggctcag ctttttcagc ggagagcatc cttccagcct
    36241 tccgcttaaa agggcaaggc gctgcctgta ttccgacagc ctcttttcca tcagccgttt
    36301 cagatcgtcc tgagcagaaa tgagccgctg ccgcttttca ttgacctgcc gtttgggatc
    36361 gtggaggcgc agacgcagcc ggtactgctc cagacggccg gacgcctcct ctgttttccg
    36421 gaacagcccc cgcctgagaa gctccccggc tcctgagagc tgttccttaa actggcggta
    36481 gtcgaacaca gccagctctg ccgccgctga cggcgtgggg gcccgcagat ccgccacata
    36541 atcggcaatc gtcacatccg tctcatgtcc caccgcggaa atcaccgggg tattgcatga
    36601 aaaaatagct ctggccacaa tctcctcgtt aaaggcccac aaatcctcaa tggagccgcc
    36661 gcctcttccc gcgatgatta cgtccactcc cagctgatcc agccgttcga ttcccatggc
    36721 aatactctcc gccgccccgt ctccctggac cttggccggg tataaaatca gctggacata
    36781 ggggttcctt ctgtgagaaa tattcataat atcacggatg gcggctcctg tgctggcagt
    36841 caccaccccc accgtcctgg cgaacatggg gatgggacgc ttatattctc tggcaaacat
    36901 gcccatctct tccagctggt tcctgagagc ctcgaaccgc ttaaacagat cccccgcccc
    36961 ggaaagctca atctgctggg catagagctg atatcttccg tctctttcat agacctccac
    37021 gctgcccttc accaccacct gctgcccgtc ctgcatctga aaaggaagcc cctttcttct
    37081 gctcgcaaac atgacggcct ggatcgcagc cagcccgtct ttcaaggtaa aataaatatg
    37141 gccggaggtg tggtacttgc agttggatac ctcccccttg attgaaatgc ggttcagggc
    37201 aaaatcctgg gaaaacatat ttttaatata ggcgtttacc tgggacactg agtaaatgct
    37261 tgccatggaa cgcctccatc tacactaatt ttgccagaat tccatttacg aaagccggag
    37321 actcgtctcc gccaaatttt ttcgccagct ccaccgcctc gttaatggca accttgtccg
    37381 gaacctcctc gtcaaagcgg atctcaaaca gcgccaggcg cagaatcgta agctccacct
    37441 ttcccatgcg gcgggtgctc cagcccttgg cagtctcgtc aatagcagcg tccagctccg
    37501 gacgcttctc cagcaccttc tccaccttag tcttcacata gccgctgtcg taaacgtcca
    37561 gctccgggca gtgaatcagt tcataaacgc cctccggtgt gtaatcatcc tctctgggct
    37621 ctgtaaaata ctgctctatc tgctccctgg tctctccctc ggaataaaaa tcagcgcaga
    37681 acagcagttt aaagcagtgt tcacgcaatt ctcttctggt cataaaacgt atcctcctga
    37741 tttcttctgt cttggtcagc cattcacaat cgactattac tctaatttat cattataact
    37801 gaatcggagg gattctacaa tagttacgca aaacttttgc agagcgcaaa actttttact
    37861 gcaaaacttt ttcctcctct aaccgtttac agctttctcc tttcacggta tactaacggt
    37921 atactataag atagaagttt tacgacagaa ttttggagga ataacaagaa tgaaagcaaa
    37981 acggatcata aaatcaggac tggccctgct tctttccatg cagctggccc tgatgtcctg
    38041 catcactgct ctggccgctc cggagtggcc aagcggtacc ggcgttctgg ctgatattgg
    38101 aattgcagtg gacgcagatt ccggcgctgt gctctttgga cagggaattc acgagctgac
    38161 gccgccggcc agtattacaa agcttctcac cgctctggtg gtagtggaga acagcagcat
    38221 ggacgacatg gttaccttct cctacgacgc ggtcaacaat gtggagtctg gaagcggcaa
    38281 taagaaaaac attgccgagg gagacaagct ttccgtcaag gactgccttt acctgctcct
    38341 tctccagtcc agcaaccagg ctgccaacgc tctggcggag catgtggctg gaagccgtga
    38401 cgccttcgca gacatgatga acgaaaaggt aaaggagctt ggctgcaccg acggcactca
    38461 ttttgccaac ccgtcaggat taaacgacga tacccaggta gtatctgcct acgatatggc
    38521 tattatcgcc caggctgcct ttaacaattc agacgtattg gaaatttcca gtaccaagtc
    38581 ctataagctg gctcccactc agaataaccc aagcggagcc acctgcgcca acgagcaccg
    38641 cctgattatc acagacgacg agacaagcga gctctactgc ccggaagcga aggcaggaaa
    38701 aacaggatac acctccctgg ccggcaatac cctcgtcacc tacggagaga aagacggcag
    38761 acgggtaatt tccgtcgttt taaaaggaca gccctctccc aactatttcc tggatggaaa
    38821 aacgctgctg cagtttggtt ttgagaattt ccagaacgta tccatcccgg acaatgagac
    38881 gaaatatgtg actggcgaag aaacggtttc cattaacgga gctgactttc agccagatga
    38941 actggaactg gaatctggcg ctgtaatcac ccttccaaag gacgccgcct tctcagacgc
    39001 ttccatggaa ctggtgacag aactgcccga gcagcatcca gagcgggcca tcgctctttt
    39061 acagtacacc tacaatgacc ggaaaattgg acaggcctac cttctggcca aggaaggctc
    39121 tctccctgca tccagtgaag agactgacgg cgccgcgccg gaggaaaagc ctggcggcaa
    39181 aaccgacgcc tccgatcaga aggacggcaa agaaggcagc attgcccttc ctcccctctc
    39241 cctcccagtt ataggcatct gccttctggt cttcgcagtg cttctcctga gcgcctatac
    39301 gctctataca aagaagaaag aggcggagga gttacggcgg cggcacgaac ggcgtatgca
    39361 gcgactcaaa gaggaaaatt atacggaaga ggaattctac gagcttctcg gcagggaaaa
    39421 agaacgcctg gccggaaagc gcagccagaa acgctcctct ggcagccgcc cgaaaaaggc
    39481 ggaaaaaaaa gcccgcagcc cgaaacagat gaaaacagag ggcgaatccc cggatgagag
    39541 cctggagaac ctggacgacc ttttctttga ggatcttgat tcttcagaag agaacaagaa
    39601 taactttgac atttaaaatc ttctataaaa gaggacatgt ttctacgctt caacgaaagc
    39661 cgcagaatcc atgtcctctt tttttgtatg cgtccctgta aatatctgac actacagcat
    39721 ttctttgaaa aaccgctgca aaatcgaaaa aagacaggaa aatttgaagt tgtaaggaaa
    39781 tctttatagt atcccgtcag taattctttt ataatgataa taggttagct cattctgaag
    39841 gcgggcaatg gaaactgatg acctatggat attaaagaac ctacagataa gaagctgatg
    39901 gggaggatac atagatgggt acagtagttc tttataatat tatttctctt attgtcatct
    39961 ttgttttagt ttttgcccta aaaattgtca ataagagtga tttaagaaga aatcaacaac
    40021 ttattattaa agtcattgcg gctatcttaa ttgtttgtgt gataacattt atacttttta
    40081 ttgatgcaat agcagttggc attataggac tggttccaaa ttaacaattt nnnnnnnnnn
    40141 cagaatgcta aacgcagtaa aaaaacagaa catattaaga ggtgtttgaa tatgccagca
    40201 tatttttctt tgacatttga actgaaaaaa actcatgatg ccatcggcgc tttttgccgg
    40261 gctttaattc attctggact tacatttaag agcggatatt ggggatttga aaacgattct
    40321 tttgaagata tgattcaatg gaatcaaaag aaattagatg aaaactttga acttggagag
    40381 aaggaacacc actcacatga ttataaacaa tttgtgtttg attatttcga cttttcagag
    40441 gtcagattat ttattatgaa taaccaaaaa gaatctacct ttacgtttga attaattgta
    40501 ccagaagacg atttaggaga atatgaggag aaggaaaatg ggaaatattc cgtacagaga
    40561 aacacaaaac gcatggagca gttgaaatct ctggcaaaaa atgtatggat tcattcttct
    40621 gttttggcga tacagacaag ctgggagtgt tcttcttgtc ctccagcggc agaaaaaatt
    40681 gcagctggca tgaaaccaca ggcggaacca ttttgtattc ttaattcttc ttctctaaaa
    40741 aatgaaacgg attttgtttt tgaaagtctt gaacgaaacg gtgtattaat cgaaaatata
    40801 acacaatgga actattaaat aagggcagac aatacattct gctgtctgct ccgttctcgc
    40861 ttaggcaaga aaaaataaaa aaatcggaag t
//
LOCUS       DBMDUW010000020        40794 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_834_length_40794_cov_3.683803, whole genome shotgun sequence.
ACCESSION   DBMDUW010000020 DBMDUW010000000
VERSION     DBMDUW010000020.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 40794)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 40794)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40794
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_834_length_40794_cov_3.683803"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..388
                     /locus_tag="ACZPCR_05655"
     CDS             <1..388
                     /locus_tag="ACZPCR_05655"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230395.1"
                     /translation="DRWLQPVDGSSQSALPPPCLTESIIRDSSLRICQTAGENPVFSS
                     SKFEKTPPFSACPGKICEKKQEKGRKEHVRKKLARELLRLRRVASATKFLSAAWRSSR
                     SVFDAIGNYFVMFLLHQKKQDVSRLL"
     gene            complement(447..1673)
                     /gene="ftsZ"
                     /locus_tag="ACZPCR_05660"
     CDS             complement(447..1673)
                     /gene="ftsZ"
                     /locus_tag="ACZPCR_05660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HIR1230396.1"
                     /translation="MLEIKINEAENAARIIVVGVGGAGNNAVNRMIEENIAGVEFIGI
                     NTDKQALQFCKATTAMQIGEKLTKGLGAGARPEIGEKAAEENQEELAQALKGADMVFV
                     TCGMGGGTGTGAAPVVAKIAKDMGILTVGVVTKPFRFEAKTRMNNAIQGIEKLKSCVD
                     TLIVIPNDKLLEIVDRRTTMPDALKKADEVLQQAVQGITDLINIPGLINLDFADVQTV
                     MTDKGIAHIGIGHAKGDDKAIEAVKQAVSSPLLETTIENASHVIINISGDISLIEANE
                     AASYVQELAGDDANIIFGAMYDENAQDEASITVIATGLDEETATPVAKAMTNFGSNPF
                     QKKQTSVAAAGREAATAAQPSQAGFRQPSPSYKPSPSLTQPGQQEPAPAPSPAPSYRP
                     MGQTQINIPDFLKHKR"
     gene            complement(1839..2570)
                     /locus_tag="ACZPCR_05665"
     CDS             complement(1839..2570)
                     /locus_tag="ACZPCR_05665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HIR1230397.1"
                     /translation="MRTYIRHRRKTGLIAALAVLAVIAVTVVSLRITEVKVSGNTRYT
                     AEEIEQTIFDSPISRNAAYCYFQYQFRPHKKLPFVEDYRIVFRGPNEVEIIVYEKSMV
                     GYVSYMNSNLYFDKDGIVVESTSEILPGIPKIEGLKFGHVVLHEPLPVENKDIFEDIL
                     NLTQILSLYEIHADGIRYQSGGQAVVTVGNLRVELGDKKDMNGKIAELSDIIQEYSDL
                     DGTLYLDTYDETNSNPMYRFQKNEP"
     gene            complement(2596..3873)
                     /gene="murA"
                     /locus_tag="ACZPCR_05670"
     CDS             complement(2596..3873)
                     /gene="murA"
                     /locus_tag="ACZPCR_05670"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HIR1230398.1"
                     /translation="MAEIEIVGGGPLRGELSVQGSKNAVLPMMAAAVLNQGVTVIEHV
                     PGIRDVRCMMEILSSLGCSCTLDKSGRLTIDAERLSGSCVRKEDMEKMRSSVILLGPL
                     LARQGKACIYYPGGCMIGKRPIDLHLKALKQFGAEIEEEKETGKVTASLKRRGGMLSG
                     AEVQLPYPSVGATENAIFAAVAAEGESFLSGCAREPEIAALCHMLNRMGARILGVGTS
                     HLRITGGLPLHGCTVRADGDRIVAGTYLIAAAAAGGEIEISGIRSEELASLTALLEEG
                     GAVVYRERDRIYLRSQRPFGRICAKTGPYPDFPTDLQSPLLALMSVSGGGMVEETVFE
                     SRFKTALELNKMGAAAEISGKLAKVAEGRRLHGCRVRACDLRGGAALVAAGLAAEGTT
                     FVEQAEYIFRGYEDICRDLSSLGGRLWYRESVA"
     gene            complement(4027..5172)
                     /locus_tag="ACZPCR_05675"
     CDS             complement(4027..5172)
                     /locus_tag="ACZPCR_05675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002603397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008955 - peptidoglycan
                     glycosyltransferase activity [Evidence IEA];
                     GO_function: GO:0015648 - lipid-linked peptidoglycan
                     transporter activity [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HIR1230399.1"
                     /translation="MADAPKKKKKKKPHRFYDYSLLLSVVFLTIFGLIMIYSASSYRA
                     QLMLGDAAYFVKRQGMIAAGSAVVMLFISKMDYHWFAKFTWLGYFTSLACMIATMLFG
                     VESHGKKRWLQIGPIQFQPTELVKISLILFLAVVISRMGLKINEFRNVRAIIIWCGVP
                     ALLITENNLSSGIITCGIVFVVLFVACKIKWPFFACAGAGIGLIAVSPYIGKALVAVR
                     LLKPYQLDRITAWVDPTATDTGYQTLQGLYAIGSGGFFGRGLGQSLQKLGFVPEPQND
                     MIFSIICEELGLFGATLLILMFMFMIYRFMVIASNAPDLMGSLLVVGVMAHIGIQVIL
                     NIAVVTNTIPNTGVTLPFISYGGTSVLFLMLEMGMVLSVSNQIKLEG"
     gene            complement(5215..6564)
                     /gene="murD"
                     /locus_tag="ACZPCR_05680"
     CDS             complement(5215..6564)
                     /gene="murD"
                     /locus_tag="ACZPCR_05680"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HIR1230400.1"
                     /translation="MSQKVLVAGSGISGIAAAKLLLGMGGEVVLYDGNEKLNEADLRQ
                     KFDEGAKVSFVLGKLDRTDLLGVELSIISPGISLEAPFVSVLQQAGIPIWSEIQLAYH
                     CAKGKLAAITGTNGKTTTTALTGEIMKAFYDSVFVVGNIGDPYTAHALETTDESVTVA
                     EVSSFQLETIMDFRPNVSAILNITPDHLDRHKTMERYIEIKEGITKNQKEEDVCVLNH
                     DDPVLREFGETLKCRVVYFSSREKLEKGLYLDGDMIVYKNDDKTVIEIVNIHDLKLLG
                     RHNHENVMAAVAVSMNMGVPMEIIRRVVKRFEAVEHRIEFVTERFGVKYYNDSKGTNP
                     DAAMQAIKAMPGPTLLIAGGYDKHSEYDEWIESFGGKVRYLVLIGQTRDKIAECAKKH
                     GFTDIMYAEDLKEAVQVCASYANAGDNVLLSPACASWGMFNNYEERGRMFKEYVRNL"
     gene            complement(6578..7549)
                     /gene="mraY"
                     /locus_tag="ACZPCR_05685"
     CDS             complement(6578..7549)
                     /gene="mraY"
                     /locus_tag="ACZPCR_05685"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008724821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HIR1230401.1"
                     /translation="MVNETILAVITAFIISAVMCPIVIPFLHKLKFGQQVREDGPQAH
                     LKKQGTPTMGGIVILGSVVITSLLYIKDYPKIIPILFMTVGFGVIGFLDDYIKIVMKR
                     SEGLNPKQKLLGQIIITGIFAYYLISSSEVGTSMLIPFTGGFDDGFFLALPLWLFVPA
                     LFFIVLGTDNGVNFTDGLDGLCTSVTILVATFFTIVAIGENTGISPITGAVVGSLLGF
                     LLFNVYPAKVFMGDTGSLALGGFVSASAFMMQMPIFIALVGLIYLVEVLSVIMQVTYF
                     KSTGGKRIFKMAPIHHHFELCGWSETRVVAVFSIITAILCLIAYLGL"
     gene            complement(7630..9363)
                     /locus_tag="ACZPCR_05690"
     CDS             complement(7630..9363)
                     /locus_tag="ACZPCR_05690"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007863641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_function: GO:0008955 - peptidoglycan
                     glycosyltransferase activity [Evidence IEA];
                     GO_function: GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HIR1230402.1"
                     /translation="MEQRRTRHRERIALLCGLLCLGMAGLTGRLFFLMTCRADEYSSM
                     ATELHQRERTLKAARGRILDRNGTVIADNRTVCTVSVVHNQIKEPEKVSEVLSRELSL
                     PAEEVKKKVEKYTSREIIRTNVDKETGDRIRDMGLAGVKVDEDYKRYYPFDEMASRVL
                     GFTGGDNQGIVGLEVEYEEWLKGQNGTILTLADAAGVEIENAAEDRIEPVAGNDLTIS
                     LDVNLQQYAQQAALQVMEKKSANQVSVIIMNPQNGEILSMVTVPEFNLNDPFTLPAGA
                     PPADPDKKQELLNQMWRNPCINDTYEPGSTFKIITAAAGLEEGVVTLKDTFSCPGFRI
                     VEDRRIRCHKAGGHGGETFLQGMMNSCNPVLIDVGQRLGTDRYYKYFEQFGLMGKTGV
                     DLPGEAATIMHRKENMGAVELATVSFGQSFQITPLQLIATASSIINGGNRVTPHFAVK
                     VENPSTGFVHEFESKEKGRILSEETSGTMRYILEQVVAEGSGKNARVPGYRIGGKTAT
                     SEKLPRSRKKYISSFLGFAPADNPQVIALITIDEPEGIYYGGTIAAPVIGGIFDNILP
                     YLGIERDQSNS"
     gene            complement(9426..11615)
                     /locus_tag="ACZPCR_05695"
     CDS             complement(9426..11615)
                     /locus_tag="ACZPCR_05695"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006775861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_function: GO:0008955 - peptidoglycan
                     glycosyltransferase activity [Evidence IEA];
                     GO_function: GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HIR1230403.1"
                     /translation="MKMSQSTNNKQPFRKYMQEKLAITVLVMMLALIALTVILYTMVQ
                     NKNEDYTQVVLSHQDYDSRTIPYRRGDIVDRNGSYLATSEKVYTLILDPKQMYEDEKK
                     ECVEPTIALLTELFGFDAEDLRSTITGKKDSSYIRYKKQMTFEEKEQFETESKARNEA
                     FTKNSEQKKILGVWFEDEYRRVYPNGSTACNVIGFAQKDGSAGSGGIEQYYNSSLVGN
                     NGREYGYLTSDSNLERVIKPAQNGNTVVSTIDLNIQKICEKYIDEWQAGIGSNVAAAI
                     VMDPKTGEILAMDTSTRYDLNNPYDLSGYYSQEEINAMDDKAKSEAWYKMWRNFCVND
                     TYEPGSPQKAFTVAGAMEENIINDSETFQCNGFLSIGGHDIHCVSRIVGHGPTTVMQG
                     LMKSCNVVMMNISRMEGVDIFAKYQSIFGFGQKTGIDLPGEADAASLIYTAENMKSAD
                     LATNSFGQNYNCTMIQMAAAYASMINGGSYYQPHVVKQILNEQGSVVDKKEPLLVRET
                     ISKETSDYINEALYQTVSGEGGTAGAAAVEGYEIAGKTGTAEKYPRSANNYLVSFIGY
                     APAHDPQVLCYVVIDTPHLEGKEQAHSTFASEIFSKIMAEVLPYMNVFPDGETAPADQ
                     EMADLPEGITSQNNGETEAPSEAPTNENGETYPVYDEEFIEEGVQYPELMPGDPSAES
                     APPEGQTAAPSQGSTEAPSQAPAAESSASGNGGGAEKPSEAKADTNT"
     gene            complement(11593..12090)
                     /locus_tag="ACZPCR_05700"
     CDS             complement(11593..12090)
                     /locus_tag="ACZPCR_05700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HIR1230404.1"
                     /translation="MAAKRHRVYDTYTDGNTVRKVKQAGKGRSGSREAAQRKRQAEDH
                     LRRSHIVRRNREKALQMDAPYVMALTLAAIITLAICMQYLALRSSITSRLGNIEKLER
                     EVEALRAENDALETSINTYVDLDYIYDVATKELGMVYANKDQILLYDKTESEYVRQYE
                     DVPEH"
     gene            complement(12142..13086)
                     /gene="rsmH"
                     /locus_tag="ACZPCR_05705"
     CDS             complement(12142..13086)
                     /gene="rsmH"
                     /locus_tag="ACZPCR_05705"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000154 - rRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HIR1230405.1"
                     /translation="MTFSHTSVLLYETVDSLNIRPDGIYVDGTLGGGGHASLVLSRLG
                     EQGRLIGLDQDADAIAAAGERLKEYGDRVTVIRTNYENIKDALASQGISGADGIYLDL
                     GVSSYQLDTADRGFTYREDDAPLDMRMDQRNTQTAKDIVNGYSEMELYRIIRDYGEDR
                     FAKNIAKHIVKARQEKEIETAGELTEIIKAAIPAKVRATGGHPSKRTFQAIRIELNRE
                     LQVLEQSIDTMIDLLNPGGRLSIITFHSLEDRIVKNKFRENENPCICPPEFPVCMCGR
                     KSKGRVVTRKPVLPSEEELAANKRSKSAKLRVFEKAGA"
     gene            complement(13083..13508)
                     /gene="mraZ"
                     /locus_tag="ACZPCR_05710"
     CDS             complement(13083..13508)
                     /gene="mraZ"
                     /locus_tag="ACZPCR_05710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HIR1230406.1"
                     /translation="MFKGEYSHTIDGKGRLIVPSKFREQLGDEFVVTKGLDGCLFVYG
                     NAEWAAFEEKLRALPLTNQNARKFTRFFLAGASDCEVDRQGRVLIPAVLRNFAHLERE
                     VVLAGVGSRIEIWNRQLWEEKNVYDDMEDIAENMEGLGI"
     gene            complement(13730..13885)
                     /locus_tag="ACZPCR_05715"
     CDS             complement(13730..13885)
                     /locus_tag="ACZPCR_05715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0E family sporulation regulatory
                     protein-aspartic acid phosphatase"
                     /protein_id="HIR1230407.1"
                     /translation="MANAKEELVEQIEKIRKKMDQCIEQREEYRKIYRYSVELDQLLN
                     QYIVAGY"
     gene            complement(13888..14763)
                     /gene="lgt"
                     /locus_tag="ACZPCR_05720"
     CDS             complement(13888..14763)
                     /gene="lgt"
                     /locus_tag="ACZPCR_05720"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HIR1230408.1"
                     /translation="MTEGADVSFVHLGITIEHLRNSISIGGFEIAFYGIIIGIGMLAG
                     LYMAQKDARRRGQDPELYLDFALYAIIFSIIGARLYYVIFDWELYKDNPIEIFNLRGG
                     GLAIYGGIIGAVLTLIVFTKVRKVSFFSMADTGCIGLITGQIIGRWGNFFNCEAFGGY
                     TDSLLAMRLKMSLVNPSMISQELLDHRIVENGVEYIQVHPTFLYESVWNLGVLAFLLW
                     YRKRKKFDGEILWMYLLGYGLGRAWIEGLRTDQLLFFGTGIPVSQALSMVLVAAASAV
                     IIWKRSKLKTGIKGE"
     gene            complement(14870..16204)
                     /locus_tag="ACZPCR_05725"
     CDS             complement(14870..16204)
                     /locus_tag="ACZPCR_05725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HIR1230409.1"
                     /translation="MSHKNGSFSSSLGFVLACVGSAVGLGNIWMFPYRLGQYGGAAFL
                     VPYIFFIVLFGLTGLSAEFAIGRRARTGTLGSYELCWGGDDKDAPAWKKGIGRIIGWI
                     PLIGSLGIAIGYSIIIGWVLRSLGGSLTGTILSTDSAEYFSQATGSFGSLPWHLAVVL
                     ITVAILLTGSVAQIEKANRIMMPVFFILFAALAVRVGFLDGAEGGYSFLFVPKWEQLK
                     NVDTWVMAMGQAFFSLSITGSGMIVYGSYLNKNADIIGASMRTAVFDTIAALLSALAI
                     MPAVFAFGIEPGSGPALMFITIPKIFSQMPMGQVFSVIFFLSVVFAGITSLINMFEAV
                     IESWQHRFQIPRRLAVALCGAICLGVGIFLEPEPFVGKWMDFITIIVVPFGAVLGAVS
                     VYYVFGYKKIKEELSEGRKAAVPAWFGALAKYLYVPLTIAVFILGIAYKGIG"
     gene            16434..17531
                     /gene="ychF"
                     /locus_tag="ACZPCR_05730"
     CDS             16434..17531
                     /gene="ychF"
                     /locus_tag="ACZPCR_05730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HIR1230410.1"
                     /translation="MKLGIVGLPNVGKSTLFNSLTKAGAESANYPFCTIDPNVGVVPV
                     PDERLQKLAALYNSAKITPAVIEFVDIAGLVKGASKGEGLGNQFLSNIREVDAIVHVV
                     RCFEDPNVVHVDGSVNPLRDIETIDLELIFSDMEILERRIAKTTKSAMGNKALTKELE
                     ILKAMYAHLEEGKLARSYETEDEDELAFIATLNLLTWKPVIFAANVAEDDLSDDGASN
                     EYVQAVRNFAAENGSEVFVICAQIEQEIAELDDDEKKMFLEDLGLTESGLDKLIAASY
                     RLLGLISYLTAGETETRAWTIKVGTKAPQAAGKIHSDFERGFIKAEVVNYQDLLDCGT
                     YTAAKEKGLVRMEGKEYVVKDGDVVLFRFNV"
     gene            complement(17669..18004)
                     /locus_tag="ACZPCR_05735"
     CDS             complement(17669..18004)
                     /locus_tag="ACZPCR_05735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007710753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HIR1230411.1"
                     /translation="MAENKNVNPDAENEEEMTVTLTLDDGRELECVVLTIFPAGDKEY
                     IALLPMDDEDSEEGEVYLYRYTEDENGAPNLENIEDDDEYEIVADAFDELLDEQEYDE
                     LVSEDELDD"
     gene            complement(18069..18716)
                     /locus_tag="ACZPCR_05740"
     CDS             complement(18069..18716)
                     /locus_tag="ACZPCR_05740"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230412.1"
                     /translation="MNRRQRPQMRLITYEMGEEYITRMDEEYPGYRDEREKLYTFVKI
                     FTGVRVIYSLFYIGLCALCGLDVTEGLVNLLSTAVFYFWYTLLLQSGWGVAALMLAAR
                     AIGLGIGGAGLLSNAPWLVAAAPGAVAAAVIFTMIAGMAMQFFEAVFCIYVLFNRQAS
                     MTVKLNRAMSVYFSKKAVSRTTLEQMAGYRNEAAEEEQEERGEENQADDENEKFT"
     gene            complement(18738..19283)
                     /locus_tag="ACZPCR_05745"
     CDS             complement(18738..19283)
                     /locus_tag="ACZPCR_05745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="HIR1230413.1"
                     /translation="MVGNMNCVHLYCGDGKGKTTAAVGLAVRMQGCGYPVVIARFLKT
                     DDSGEVRALKNLPGITVIPCKKTFGFTWQMTREEKKEAALYYSGLFETAVSLAREACA
                     KAGQALLILDEIAAAVGNGFVEEEQVLDFLEKRPQNLETVLTGRNPSARMTEAADYVS
                     EILCRKHPFEQGTGARRGIEF"
     gene            complement(19277..21130)
                     /locus_tag="ACZPCR_05750"
     CDS             complement(19277..21130)
                     /locus_tag="ACZPCR_05750"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012742663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HIR1230414.1"
                     /translation="MPFNEAQSAAVSHKDGPMMVLAGPGSGKTTVVTHRVQSLIEKHG
                     VNPSSILVITFTRAAAREMKERFERLMEGRPMRGQVSFGTFHSVFFRILKLAYQYDAS
                     DIIREDQKLRLIRELTAKEQLEPEDENELISSLISEISAVKGEQIDLEHYYAKSCSGD
                     SFRRIYRGYEEQLQRAHKIDFDDMLVMCWDLFRKRPDILSAWQKKYEYILVDEFQDIN
                     RLQYQIVRMLAAPSDNLFIVGDDDQSIYRFRGAKPEIMLGFERDYPKAARVLLDVNYR
                     STREIVEASLRLIEHNEKRFKKSLKTAGSRGRGVITRIWEDEEEENSRIAEEIRMYAE
                     AGCSYSDIAVLYRTNSGPKRLIEKLMEHNLPFRARDQVPNLYEHWISQNILSYIRVAL
                     GNRDRAEVLQMINRPARYVGRDALRDPQVSFEQLKAYYKDKDWMVERIENLEFDLTAV
                     SRMSPLAAVNYIRKSIGYDAWLYEYAAAHHVKAEELLETAEQLRESAARYKTFDAWFE
                     HIRAYGEELKRQAREREEQADAVMLSTMHSSKGLEYRVVYILDANEGVTPHNKAVLDA
                     DIEEERRLFYVAMTRAKQRLHVYGVKNRYHKPAEVSRFVEEYLEEQDGKEW"
     gene            complement(21246..22697)
                     /gene="gltX"
                     /locus_tag="ACZPCR_05755"
     CDS             complement(21246..22697)
                     /gene="gltX"
                     /locus_tag="ACZPCR_05755"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015520425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HIR1230415.1"
                     /translation="MEKIRTRYAPSPTGKMHVGNLRTALYAYLITKHEGGDYILRIED
                     TDQERYVEGATEIIYNTLKDTGLIHDEGPDVGGPVGPYIQSERQKSGIYMKYAKELID
                     KGEAYYCFCDQERLNSLKKTVNGEEIMAYDKHCLHLSKEEVEANLAAGKPFVIRQNNP
                     TEGTTTFHDEIYGDISVDNSELDDMVLIKSDGFPTYNFANVVDDHLQKITHVVRGNEY
                     LSSSPKYNRLYEAFGWEVPVYVHCPTITNEEHKKLSKRSGHSSYQDLIDQGFLSEAVV
                     NFVALLGWSPEGNQELFTLDELIKEFDYRHISKSPAVFDMVKLRWMNGEYMKSMDFDK
                     FYEMAEPYIREVIKKNLDLRKIAAMVKTRIEVFPDIAGHIDFFEELPEYDPQMYVHKK
                     MKSTEETSLKVLKDVLPILEAQEDFSNDALYERLSAYISETGVKTGFVMWPIRTAVSG
                     KQMTPAGATEIMEVLGKEESLERIRKGIELLEK"
     gene            complement(22795..24147)
                     /gene="mgtE"
                     /locus_tag="ACZPCR_05760"
     CDS             complement(22795..24147)
                     /gene="mgtE"
                     /locus_tag="ACZPCR_05760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HIR1230416.1"
                     /translation="MEEMNFDELHALADEKQYRSLKEKLIEMNEVDIASFMEELDSEK
                     TVVVFRTLPKEIASDVFACLPVEKQQHIITSITDNELQYIMDDLFVDDAVDMLEELPA
                     TIVKRVLKNSSPDTRKLINQFLKYPDNSAGSVMTAEYVGLKKAMTVEEAFAYIRKYGV
                     DKETIYTCYVMDAGRHLEGVVTVKDLLMSPYATTIEEIMDSHVLKAHTTDDQEAVADL
                     FNEYDLLSLPVVDGENRLVGIITVDDVMDVMEQEATEDFEKMAAMNPSEKPYLKTGVF
                     QLAKNRIVWLLILMFSSMVTGEILTTYEEAFSAVPLLVTFIPMLMNTGGNSGSQASTM
                     IIRGMAVGEISPSDLAKVVWKELRVGILVGICLAIANFVRLTLSYPGQEMICLTVVLS
                     IFCIVIIAKTIGCTLPIIAKVLHMDPALMASPMISTILDACSLVIYFNFACRLLDMAA
                     "
     gene            complement(24221..25261)
                     /locus_tag="ACZPCR_05765"
     CDS             complement(24221..25261)
                     /locus_tag="ACZPCR_05765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230417.1"
                     /translation="MNKMGLWFYLSLKRQTKRLFFLLLLLALPAGLWLLREAERPEED
                     AIAIALYAGESDWNRRVADELLSGEHSFEFYLSSSEEELREDVAARRAECGYIFSEDL
                     LEKLESGRFKRSITLVTAPSTAVDKLSSEVVFSGLFTVWGRSLLETYSREGEVFQGEK
                     EVWKRLEPMYDHYLENGSTFAFQYETEEGTQLGKPSMKQTFPARGLTAVFIFVMGLTA
                     AVTVCEDEKRGLFSTLSGLGREAAVFSCLAAPVFLSCVSGFAALAAAGELSSSSWILE
                     GIRLIVYGGMCTLFSWGLCRIVKNPLAVACLIPFFASASLILCPVFIDLSMFLPWASA
                     AAKFFLPYYYLV"
     gene            complement(25254..26465)
                     /locus_tag="ACZPCR_05770"
     CDS             complement(25254..26465)
                     /locus_tag="ACZPCR_05770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1230418.1"
                     /translation="MGRFLTILKIEMKRALKSLPYFLAGAVVLAVLAGTIAFSANRML
                     YGEQSVGSIQVGVAVPEADRGAKWIMSMVSSLESVSSLCEFVYLDEEEGRRQMEKGAI
                     YALMLIPDQLLEGIMNGTNDPVTIVFPEQAGLEASIFRELTDAGTEILKTAQAAVYST
                     DELLGDMGRTGQIPQAESDLNQMYLKYALSRSVYFKTEQVSASGDVTTEVFYGISCAV
                     LAVLLLGIPASGFLRSFSPVMEKKLYLSGFSRPMRLWARTAALAFLFALATAVPFFIC
                     FVKGFFQSGLFSIPVWLLVCVCASGWVILIYEAGRSTLAGVSILFLSTIVMMFMAGGL
                     IPSVFLPEAAAGAGKFTPVFFLMEAVKWMVSEDMSGRAGQLAAWAPVLRLLVLEGAAF
                     CLAAAVRRAYE"
     gene            complement(26487..28361)
                     /locus_tag="ACZPCR_05775"
     CDS             complement(26487..28361)
                     /locus_tag="ACZPCR_05775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230419.1"
                     /translation="MKCPYCDQEIPDGSAECPVCKKNLMEASNETEPNGAAGGENQSG
                     QTEAGSAGEPAELAVAEKKPNKIWMAGAAAAAVAVVGGVAFWQMNKPDPKDVVIDAFK
                     GVVAEGQTDPMEEIFGWKALGEKLYSDSYQVGMNLTLGELLGSSELQGTGFSINARED
                     RSSSTMDMDLGFQYGDIPMFNAKFYLDNSEMAIALPPDMTNKVFTLNLEEDLNTQIAN
                     SPYLGKSLSDMGMDLQAYADYMKKANELSHSETPMFDFGALWDRYKTGSKAVDNLKAA
                     MTVEKGESKSCPVGDAEVECDGYDVVLSNAALVQFFTETKDFFLADETLKKDMITYLE
                     LVYDLNASLYGSEEMAQLYGMESPDMTPEQQQTELWTSADEEVEALLSQLKGAMGDVT
                     LAVYVTDDGKLASFDYSTELSLADQTAEAETAAAEEESAASAEAADTLKLYGTVNFRG
                     GYSQTANIEANLTAEEPSGEKIVIDMAKMGEYEKDKLYQAQLALQVEAAGEKMLFSMS
                     GEYDIPTANYTIDAYAEENDTEVGSIRIDGIMEDLVPGESFNAVVDSLRVTAGPADEG
                     MLLAELSGSYGIKPLEEAVSKPEGESFDILAATEEEWNTVIMELYMGLTSMLSGAGLS
                     "
     gene            complement(28472..29149)
                     /gene="ccmA"
                     /locus_tag="ACZPCR_05780"
     CDS             complement(28472..29149)
                     /gene="ccmA"
                     /locus_tag="ACZPCR_05780"
                     /EC_number="7.6.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015439 - ABC-type heme transporter
                     activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015886 - heme transport [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC exporter ATP-binding protein CcmA"
                     /protein_id="HIR1230420.1"
                     /translation="MLEVSGIYKKFKKRQILNGASFTAVPGQCVGIAGGNGCGKTTLL
                     SILAGVSRPDQGSIRFDGEEAVGRRSVFEKRAAYVPQENPLIPELTARDNFALWYRGD
                     KKKMERDLEQGVAKTLGISQFLDVPAGKLSGGQKKRLSIAAALSNQASLLIMDEPGAA
                     LDLGAKEEILHYIRTFTQGGGTVILTSHEMPELQACSALYILKEGVLIPESIENGVEP
                     EKLIGKF"
     gene            complement(29219..31327)
                     /locus_tag="ACZPCR_05785"
     CDS             complement(29219..31327)
                     /locus_tag="ACZPCR_05785"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HIR1230421.1"
                     /translation="MYKSFSMELAGRTLTVDVGRVAAQANGAAFMHYGDTTVLSTATA
                     SDKPRDGIDFFPLSVEFEEKMYAVGKIPGGFNKREGKASENAVLTARVIDRPMRPLFP
                     KDYRNDVTLNNLVLSVDPECSPEYTAMLGSAIATCISDIPFDGPCATTQIGMIDGEFI
                     VNPTAAQRKISDMALTVASTREKVIMIEAGAKEVPEDVMIQAIFKAHEVNQDIIKFID
                     TIVAECGKEKHSYESCAVPEELFAAIKEIVPQEEMEAAVFTDEKQKREENIKAITERL
                     EEAFAENEEWLAVLGEAVYQYQKKTVRKMILKDHKRPDGRGITEIRPLAAEIDIVPRV
                     HGSGMFTRGQTQILNVCTLAPLSEAQKIDGLDENETSKRYMHHYNFPSYSVGETKPSR
                     GPGRREIGHGALAEKALIPVLPSEEEFPYAIRTVSETMESNGSTSQASICASTLSLMA
                     AGVPIKAPVAGISCGLVTGDTDDDYIVLTDIQGLEDFFGDMDFKVGGTHKGITSIQMD
                     IKIHGLTRPIIEEAIAKTREARLYILDEIMKPVIAEPRKEVGEFAPKIEQITIDPQKI
                     GDVVGKQGKVINKIIEQTGVKIDISDDGSVSVCGTDKAMIDKAISIIKSIVTEIEPGQ
                     ILTGTVVRIMNFGAFVELAPNKDGMIHISKLSDKRVAKVEDVVNIGDEVTVKVIEVDK
                     MGRINLSMKPGDLNQEAHKE"
     gene            complement(31607..31873)
                     /gene="rpsO"
                     /locus_tag="ACZPCR_05790"
     CDS             complement(31607..31873)
                     /gene="rpsO"
                     /locus_tag="ACZPCR_05790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HIR1230422.1"
                     /translation="MISKEKKSAIIAEYGRKPGDTGSPEVQIAILTARITELTEHLKA
                     NQKDHHSRRGLLKMVGQRRGLLDYLKKTDLEGYRALIEKLGIRK"
     gene            complement(32027..32338)
                     /locus_tag="ACZPCR_05795"
     CDS             complement(32027..32338)
                     /locus_tag="ACZPCR_05795"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230423.1"
                     /translation="MDKVLLFVLTAGVLGAAAAVSASIYFLIKRKRFWRRALTAAMLA
                     ELAASSGAMGLTWFCILMEDFERLNQMISVVSLTVAGESILVIGLWGIGKIWERRWDG
                     E"
     gene            complement(32331..33659)
                     /locus_tag="ACZPCR_05800"
     CDS             complement(32331..33659)
                     /locus_tag="ACZPCR_05800"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230424.1"
                     /translation="MRYRWKGIFLAAAAACLLTGCQGAQDGEPVHNPVPEQQEQTKHP
                     EAEEALGRALQAVESQFPDRRFEPLPEEETEKAVSFFKDSYLFSGRKSEDGYSYILGI
                     CLIKENPLEGLTCGKDWSGAGYSASQFHNGQFLLLEKGDTSSGISSLSAALEEGMEGI
                     SYLEEAEKRGAFLVPPQEEGFWKTYSIQNGKLYAELVREETAPEAQGFSPEFLEENGA
                     VVKAELSGTFENGERTESLGNREDLEKLGALLSEAEKEELPMNEYFPGKLTLTMESEE
                     TKELWLSFPDSEGSIPELAAGGSSFYTWDGEQSEAVWRLFGTVYGFGAYGEQIWMEMD
                     PRQVTAEDSELSFILHNDTGRSIQYILSPAIEKKTEKDGKESWEQVESLAGFCGYLTE
                     LSEESVRLAVPWKGSFAPDGPGTYRLRIQVLSEEELRFGVEAEFEVADHG"
     gene            complement(33743..35626)
                     /locus_tag="ACZPCR_05805"
     CDS             complement(33743..35626)
                     /locus_tag="ACZPCR_05805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006772323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HIR1230425.1"
                     /translation="MIDGLEKNENLKGSPQTGRPSENSSSDREGQGRSRARGRSRRKG
                     TAEPSGMAERRKPVSRQPKDPGDGGGFHWGRKQTAIAAGAAAAVLVIGGISYAGMSSR
                     YSRVFFPGTEINGLDVAGKTAAEAQEMIAGGINGYVLTIEERGEKTEQISQKDIGLQA
                     KFDGSLEKIIASQNPFAWGLRVFSPDSYQIQTMMEYDEEAFETALKGLACFDEETAKE
                     PENARLSDYSKENGYTIVPEKEGTLADYELVEKEVSEAILKLETNISLEELGAYQEPE
                     VTADDETLKTLCENMNKAAGVTITYKFGDQTETLSGDRIHEWLVPNADGSAGVDSGKV
                     SAYVKELADKYNTNHKSKTLKTSYGKTVTIKGGSYGWKINQAEEADELAALIRSGESQ
                     SGREPVYSQKAASHGANDYGDTYVEINLTAQHLFFYKDGALLVESDFVSGNLSKGWGT
                     PAGSFPLTYKQRDAVLKGENYRTPVDYWMPFNGGIGMHDATWRSEFGGTIYKTGGSHG
                     CINLPHSVAKKIYENISAGMPVLCYNLEGTEKPSAPAKPQETEPSTQAPAPSEPSSEA
                     AKPSEPAKPSQEAPSEPSKEQVQPTKPAETPAPTQPETTAPEGPAGPASQGENSGPAG
                     PGA"
     gene            complement(35920..37074)
                     /gene="dnaJ"
                     /locus_tag="ACZPCR_05810"
     CDS             complement(35920..37074)
                     /gene="dnaJ"
                     /locus_tag="ACZPCR_05810"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002575014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HIR1230426.1"
                     /translation="MAESKRDYYEVLGVSKDADDAALKKAYRTLAKKYHPDANPGDKE
                     AEKKFKEASEAYSVLSDPQKRQQYDQFGHAAFDGGAGAGAGGFGGFDFSGADMGDIFG
                     DFFGDIFGGGRSRGRSNGPMKGANVRTSIRITFEEAIFGCEKEIELDLKETCEKCHGT
                     GAKPGTQPQTCSKCNGKGKIMYTQQSFFGQVQNVQTCPDCRGTGKIIKEKCPDCYGTG
                     YVTRRKKIKVTIPAGIDNGQMLRDRGNGEPGVNGGERGDLLVEVIVSNHPVFKRQDTS
                     IYSTVPISFAKAALGGAIRIKTVDGEVEYEVKPGTQTDTRVRLKGKGVPSLRNKNVRG
                     DHFVTLVVQVPEKLTEEQKEALRRFDDAMNGVAPEGNEKHKKKGLFGGRL"
     gene            complement(37165..39027)
                     /gene="dnaK"
                     /locus_tag="ACZPCR_05815"
     CDS             complement(37165..39027)
                     /gene="dnaK"
                     /locus_tag="ACZPCR_05815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005540336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HIR1230427.1"
                     /translation="MSKIIGIDLGTTNSCVAVMEGGKPVVIANTEGVRTTPSVVAFTK
                     TGERLVGEPAKRQAVTNAEKTITSIKRHMGTDYKVSIDDKKYSPQEISAMILQKLKAD
                     AEAYLGEKVTEAVITVPAYFNDAQRQATKDAGKIAGLDVKRIINEPTAAALAYGLDNE
                     KEQKIMVYDLGGGTFDVSIIEIGDGVIEVLSTNGDTRLGGDDFDNRITQWMIDEFKKA
                     EGVDLSADKMALQRLKEAAEKAKKELSTATTTNINLPFITATSEGPKHLDMNLSRAKF
                     DELTHDLIERTAIPVQNALKDAGLTASELSKVLLVGGSTRMLAAQEKVKQLTGQEPSK
                     TLNPDECVALGAAIQGGKLAGDAGAGDILLLDVTPLSLSIETMGGIATKLIERNTTIP
                     TKKSQIFSTAADNQTAVDIHVVQGERQFARDNKTLGQFRLDGIPPARRGVPQIEVTFD
                     IDANGIVNVSAKDLGTGKEQHITITSGSNMSDSDIEKAVKEAAEYEAQDKKRKEAIDA
                     RNDADSMVFQTEKALEEVGDKIDANDKAAVEADLNALKEAINRAPIDQMTDAQVEDIK
                     AGKEKLMASAQALFAKVYEQAQAAGAAGQAGPAPDMGASQGADDNVVDGDFKEV"
     gene            complement(39083..39706)
                     /gene="grpE"
                     /locus_tag="ACZPCR_05820"
     CDS             complement(39083..39706)
                     /gene="grpE"
                     /locus_tag="ACZPCR_05820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000774 - adenyl-nucleotide exchange
                     factor activity [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0051087 - protein-folding chaperone
                     binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HIR1230428.1"
                     /translation="MSEEMKDRECTEAEMENEAGTCTDSAAQNCGEEQKEEGDGRAGE
                     NEAAPDASQPEKKGFFSKKKDKRDQQIEELTDQLKRNMAEFDNFRKRTEKEKSAMYEI
                     GAKDVIEKILPVIDNFERGLKAVPEGGDAFAEGMNMIYKQLLKTLEDLGVKPIEAVGQ
                     PFDPNFHNAVMHIEDENFGENVIAEEFQKGYLYRDSVVRHSMVKVAN"
     gene            complement(39742..40773)
                     /gene="hrcA"
                     /locus_tag="ACZPCR_05825"
     CDS             complement(39742..40773)
                     /gene="hrcA"
                     /locus_tag="ACZPCR_05825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HIR1230429.1"
                     /translation="MELGERKERILKAIIQTYLETGEPVGSRTISKYSDLNLSSATIR
                     NEMSDLEELGYIIQPHTSAGRIPSDKGYRFYVDHIIREKEDEVTEIKELMIQKVDRVE
                     LLLKQMASVLAANTNYATMISGPHYHQTKIKFIQLSRMEAGKLLIVTVLEGNIIKNSM
                     VALDGELSEEELLNLNILLNNALNGLTVDQINLGVITKMKEQAGSRRQIVDLVLNEVA
                     EAIKANEEDLQIYTSGATNIFKYPELSDGHKASELLGTLEQKELLRNLLSDTPQEQES
                     TGIQVYIGDETPVQSMKDCSVVTANYVLSDGLRGTIGIIGPKRMDYEKVVNTLRSLMN
                     QLEATFHKE"
BASE COUNT         8971 a        12069 c         8980 g        10774 t
ORIGIN      
        1 ggacaggtgg ttacagccgg tggacgggtc atcgcagtca gctctgccac ccccctgtct
       61 gacagagtct attataaggg acagctccct cagaatttgt caaacggcgg gggaaaatcc
      121 tgttttttca tcgtcaaagt tcgagaagac tcctcctttt tccgcttgtc ccggcaaaat
      181 ctgcgaaaag aagcaggaaa aaggcagaaa agagcatgta agaaagaagc tcgcccgcga
      241 gcttctccgc ctgcggcggg tcgcttctgc gacaaaattc ctttccgccg catggcgatc
      301 ctcgcggagc gtttttgatg caataggaaa ttacttcgta atgttcctat tgcatcaaaa
      361 aaagcaggac gtttcccggc tcctgtgagc ttatggaaaa cgttctgctt tctttcattt
      421 cactttgaaa tgctgcttat gcttttttat ctcttatgct ttaagaaatc aggaatattg
      481 atctgtgtct gtcccatcgg tctgtaggac ggcgctggtg aaggcgccgg agctggctcc
      541 tgctgtcccg gctgtgttaa agaaggggac ggcttgtaag acggagacgg ctggcggaat
      601 cctgcctgag acggctgagc tgccgtagct gcctctctgc ctgctgctgc cacggaagtc
      661 tgcttcttct ggaacggatt gcttccgaaa ttagtcatgg ccttggcaac cggagtcgct
      721 gtctcctcgt ccaggcctgt ggcaatgact gtgatggaag cctcgtcctg agcgttctcg
      781 tcgtacatag cgccgaagat aatgttcgca tcgtcgcctg ccagctcctg aacgtaggaa
      841 gctgcctcgt tagcctcgat caggctgata tctccggaaa tattgataat tacatgggac
      901 gcattctcaa tggtggtctc cagaagcggg ctggatacgg cctgcttaac agcctcgatg
      961 gccttgtcgt ctcctttggc atgtccgatt ccaatgtgag cgattccctt gtcagtcata
     1021 accgtctgaa cgtctgcaaa gtccagattg atcaggccag gaatattaat taaatctgtg
     1081 attccctgaa ctgcctgctg aagcacttcg tctgccttct ttaatgcgtc cggcatagtg
     1141 gttcttctgt ccacgatctc cagcagcttg tcgttgggga ttacgatcag agtgtccacg
     1201 cagctcttta acttctcaat gccctggatg gcgttattca tacgtgtctt ggcctcaaaa
     1261 cggaacggct tcgttacaac gccgactgtc aggattccca tatccttagc aattttagcc
     1321 acaacaggag ctgctcctgt tccggttccg ccgcccatac cgcaggtaac gaacaccata
     1381 tccgctccct ttaacgcctg ggctaactcc tcctggttct cctcagctgc cttctcgccg
     1441 atctccggtc ttgcgcctgc gcccagtccc ttggtcagct tctcgccgat ctgcatggct
     1501 gtggtagcct tgcagaactg gagagcctgc ttatctgtat tgataccgat aaactcaacg
     1561 cctgcaatgt tctcctcgat catgcggttt accgcgttat ttccggctcc gcccacgcct
     1621 actactataa ttctggcggc attctctgct tcatttatct taatctctaa caagaaaact
     1681 tcctccttca ctcacatatc tgctgttttt tgcctgcatt tgcgccttct gatttcagtc
     1741 tatctaatac tatattttat tttaggaaaa atatcaactg ttattttgcc gaatttatga
     1801 ttttcacacc agttcagcta tgggaacggg ccgcaatgct acggctcatt tttctgaaac
     1861 cggtacatgg gattggagtt tgtctcgtcg tatgtgtcca ggtacagcgt tccgtccaaa
     1921 tcggaatact cctggataat gtcgctcagc tccgctatct tgccgttcat atccttttta
     1981 tctcccagct caactctcag attccccact gtgaccacag cctgtcctcc gctctggtac
     2041 cggatcccgt cggcgtggat ctcatagaga gagagaatct gggtcaggtt caaaatatcc
     2101 tcgaaaatat ccttattctc tacgggaagg ggctcgtgaa gcactacatg gccaaacttc
     2161 agcccctcta tcttcggtat tccaggcaga atttcgcttg tgctctccac aacaattccg
     2221 tctttgtcaa agtacaggtt gctgttcatg taggacacat agcctaccat gcttttttca
     2281 tatacaataa tctccacttc attgggacct ctgaatacta tcctgtagtc ttccacaaac
     2341 ggaagcttct tatgaggcct gaactgatac tggaaataac agtaagcggc gtttcggctg
     2401 attggggagt caaatatggt ctgttcaatc tcctcagccg tatatcttgt attgccgctt
     2461 accttcacct ccgtaatccg cagagatacc acggtaacag ctatgaccgc cagcacggcc
     2521 aaagctgcaa tcaggcctgt ttttcttctg tgtctgatat atgtcctcat atctgtacct
     2581 cctgccggaa ctgtttcatg ccactgattc ccgataccag agccttcctc ccagactgct
     2641 taaatcgcgg cagatatcct cgtatcccct gaaaatgtat tctgcctgct ctacgaacgt
     2701 ggttccctct gccgccaggc ctgccgccac aagggcagcc ccgcctctca gatcacaggc
     2761 tctgacacgg cagccatgga ggcgtcttcc ctctgccacc tttgccagtt ttcccgatat
     2821 ctctgcagcc gcccccatct tgttcagctc cagagccgtc ttaaaacggc tttcaaaaac
     2881 cgtttcctcc accattcccc cgcctgaaac gctcataaga gccagcagcg gagactgaag
     2941 atccgtagga aaatcaggat acgggcctgt cttggcgcag atccgcccaa aaggcctttg
     3001 gctccgcagg tagattctgt cccgctcccg gtagaccacg gctcctccct cctccaggag
     3061 agccgtcagg cttgcaagct cctctgagcg gattccggaa atctcaatct ctcctcccgc
     3121 tgcagccgct gcaatcagat aggttcccgc cacaatcctg tctccgtctg cccgcactgt
     3181 acagccatga agaggaagcc ctcctgtaat ccggagatga gaagttccga cgcccagaat
     3241 cctggccccc atcctgttta acatatggca gagagccgct atctccggtt cccgcgcaca
     3301 gccggataaa aagctttctc cctcagcggc cacagcggca aaaatggcat tttccgtagc
     3361 gcccacgctc ggatagggaa gctgtacttc tgctcctgac agcattcctc cccttctctt
     3421 cagggaagcc gtcactttcc cggtttcctt ctcctcctca atctccgccc caaactgctt
     3481 cagcgccttc aggtggagat caatgggccg ttttccaatc atgcagccgc ctggatagta
     3541 aatgcaggcc tttccctgcc tggccagcag cggccccaga agaatcaccg atgagcgcat
     3601 tttttccatg tcctctttcc tgacgcagct tccggaaagg cgctctgcgt caatcgtcag
     3661 ccgcccgctt ttatccagag tacagctgca tcccagggaa gagagtattt ccatcataca
     3721 gcggacgtcc ctgataccag gaacgtgttc aatcactgtg actccctgat ttaaaacagc
     3781 ggcggccatc atgggaagca cagcgttttt agacccctga acggacagtt ctcctctcag
     3841 aggccctcct ccaacaatct cgatttcagc caaggcagca gttcccttct gtttccttat
     3901 attatcctat gcccggcttc ctgtttttgt gacagctgga cgcctgaaac cgtctggtaa
     3961 aaaccgataa gaagaaaggg aggattttcc gctttatttc tgaagaaaat cctccctctc
     4021 cggcatctac ccctccagtt taatctggtt ggagacgctc agcaccattc ccatctccag
     4081 catcaggaac agaaccgagg ttcctccgta gctgataaag ggaagcgtaa ctcctgtgtt
     4141 tggaatcgta ttcgttacaa cggcgatatt cagaatgacc tgaatgccga tatgggccat
     4201 cacgcccacc acaagcagag aacccatgag atccggcgcg ttgctggcga ttaccataaa
     4261 ccggtagatc ataaacatga acataagaat cagaagcgtc gctccaaaca ggcccagctc
     4321 ttcacaaatg atggaaaaaa tcatatcgtt ctggggctcc ggcacaaagc caagcttctg
     4381 aaggctctgt cccagtcctc ttccgaaaaa gccgccggag ccgatggcgt acagaccctg
     4441 gagcgtctga tatcctgtgt ccgtagccgt cggatccacc cacgcggtga tacggtccag
     4501 ctgataaggc tttaacagcc tgactgccac cagggccttt cctatgtagg gcgacacggc
     4561 aatcaggcct atgccagctc ccgcgcaggc aaagaagggc cacttgatct tgcacgccac
     4621 aaacagcact acaaatacaa tgccgcaggt gatgattccg gagcttaggt tattctctgt
     4681 aatcagcaga gccgggacgc cgcaccagat gatgatggcc cgcacattcc gaaattcatt
     4741 gatcttaagc cccattctgg aaatcacaac tgccagaaac agaataagcg aaatctttac
     4801 cagctctgtg ggctgaaact gaatcgggcc aatctgaagc catctcttct ttccgtggga
     4861 ttccacgcca aagagcatgg tggcaatcat acaggccagg gacgtgaagt agcccagcca
     4921 ggtaaacttg gcaaaccagt gataatccat ttttgagata aacagcatca ctaccgcgct
     4981 gcccgctgca atcatgccct ggcgcttcac aaaatacgca gcatccccca gcatcagctg
     5041 cgcccggtag gagctggcgc tgtaaatcat aataagcccg aatatcgtca gaaacacgac
     5101 ggacagaaga agactgtaat cgtagaaccg atggggcttt ttcttcttct tttttttcgg
     5161 cgcgtcagcc atcttaccac tccttacctg tgtctgcgtc tatctgcttc attcctagag
     5221 atttctcaca tattccttga acatgcggcc tctctcctca taattattaa acatgcccca
     5281 gcttgcgcag gccggtgaaa gaagcacgtt gtccccggcg ttggcgtagg aggcgcacac
     5341 ctgcaccgct tcctttaaat cctccgcata catgatgtcg gtaaagccat gctttttcgc
     5401 gcactcggca atcttatccc tcgtctgtcc gatcagcacc aggtagcgca ccttgccgcc
     5461 gaagctctca atccactcgt catactctga gtgcttgtca tagcctccgg cgatgagaag
     5521 cgtgggcccc ggcatggcct tgatcgcctg catggccgca tccgggttcg ttcccttgga
     5581 atcgttgtaa tattttactc caaagcgctc tgtgacaaac tcaattctgt gttcaaccgc
     5641 ctcgaagcgc ttcaccaccc ggcggatgat ctccatgggc acgcccatgt tcatgctgac
     5701 agccacagcg gccatgacgt tttcatggtt atggcggcct aacagcttca gatcgtggat
     5761 attcacaatc tctatcacgg ttttgtcatc gttcttatat acgatcatat cgccgtccag
     5821 gtaaaggccc ttctccagtt tctcccggct ggagaagtaa accactctgc acttcaaggt
     5881 ctctccgaac tcccgcagca ctggatcgtc gtggtttaat acgcagacgt cctcctcctt
     5941 ctggttcttt gtgatgcctt ctttgatctc gatgtaccgc tccatcgtct tatggcggtc
     6001 caggtgatcc ggagtgatat tgaggatcgc gctgacattg ggcctgaaat ccataatcgt
     6061 ctccagctgg aagctggaaa cctccgctac cgttacagac tcatctgtcg tctccagggc
     6121 gtgggctgtg tagggatctc cgatatttcc cactacaaac acgctgtcgt aaaaagcctt
     6181 cataatctcc cctgtcagag ccgtggtagt ggtttttccg tttgttcccg taattgccgc
     6241 cagctttccc ttagcgcagt ggtaggccag ctggatctcg ctccagatgg ggattcccgc
     6301 ctgctgaaga acggacacga aaggagcttc cagggaaatg cccgggctga taatggagag
     6361 ctccacgcct aaaagatctg tgcggtctaa ttttccaagg acaaagctca cctttgcccc
     6421 ctcgtcaaat ttctgtctca aatccgcctc gttcagcttc tcattgccgt cgtagaggac
     6481 aacctctcct cccatgccca gaaggagctt tgccgctgca atgccgctga ttccgcttcc
     6541 tgctaccaat actttctgac tcattgtcca tttcctccta taatcctaag tatgcaatca
     6601 gacaaaggat tgctgttata atagaaaata ctgcgactac tcttgtttca gaccatccgc
     6661 acagctcaaa gtgatggtgg ataggcgcca tcttgaagat gcgctttcca cctgtgctct
     6721 taaagtaggt cacctgcatg atcacagaca gcacctctac cagataaatc aggcccacca
     6781 gagcaatgaa aatgggcatc tgcatcataa aggcgctggc cgacacaaag ccgcccagag
     6841 ccagagaacc tgtatctccc ataaacacct tggccggata cacattaaac agcagaaagc
     6901 ccagaagact tcccactacg gctcctgtaa tcgggctgat tcctgtattc tctccaatgg
     6961 ccacaattgt gaagaaggta gccaccagaa tggtgacgct ggtgcacagt ccgtccagtc
     7021 cgtctgtaaa attcactccg ttgtccgttc caagaacaat gaaaaacagc gccggaacaa
     7081 acagccacag cggaagagcc aggaaaaatc cgtcgtcaaa gcctcctgta aagggaatca
     7141 gcatggaagt tcccacctcg ctgctgctga tcagatagta ggcaaaaatt cccgtaatga
     7201 taatctggcc aagcagcttc tgcttggggt tcaatccctc ggaccgcttc atcacaatct
     7261 taatgtaatc gtccagaaag ccgatcactc cgaatcccac tgtcataaac agaatgggaa
     7321 taattttcgg atagtccttt atatagagta acgaggtaat cacgacggaa cctaaaatta
     7381 caatcccacc catagtgggc gtgccctgct tttttaagtg ggcctggggg ccgtcctccc
     7441 tcacctgctg cccgaatttg agcttgtgca gaaagggaat tacaatcggg cacataactg
     7501 cgctgataat aaatgccgtg ataaccgcaa gaattgtctc atttaccatg tcacacctca
     7561 gattcttatg tagtcttttg ttgagctgtc ctagactcct gattagtata cgtctttttt
     7621 cctgaataat caactgttac tttggtcccg ttcaatcccc agatagggca gaatattgtc
     7681 gaaaatcccg ccgatgacag gggccgcaat ggtgcctccg taataaattc cctccggctc
     7741 gtcgatggtg atcagggcga tgacctgggg attgtcagcc ggcgcgaagc ccagaaagga
     7801 ggaaatatat ttttttctgc ttctgggcag cttttccgag gtagcggtct ttcctccgat
     7861 ccggtagcct ggaactctgg cgttttttcc gcttccctcc gccactacct gttccagaat
     7921 atagcgcatg gttccgcttg tctcctctga gagaattctt cccttttcct tactctcaaa
     7981 ttcatggaca aagcctgtgg atggattttc cacctttacg gcgaaatggg gcgtcacccg
     8041 gtttcccccg ttgatgatgg aggaggctgt ggcaatcagc tggagaggcg taatctggaa
     8101 ggactgtcca aaggacaccg ttgccagctc cactgctccc atgttctcct tcctgtgcat
     8161 gatagtggcc gcttctcccg gcagatccac ccctgttttt cccatgaggc cgaactgttc
     8221 aaaatatttg taatagcggt ccgttcccag acgctgtccc acgtcaataa gcacaggatt
     8281 gcaggaattc atcatcccct gaaggaaggt ctcccctccg tgtcctcccg ccttgtggca
     8341 ccggattctc cgatcctcca caatccggaa gcccggacag gaaaaggtgt ccttgagcgt
     8401 aacgactccc tcctccagcc ctgcggcggc tgttataatc ttaaaggtcg aacctggctc
     8461 gtaggtatcg ttgatgcagg gatttctcca catctggttt aacagctcct gttttttatc
     8521 cggatccgca ggcggcgcgc ctgccggcag agtgaaggga tcgtttaaat taaattccgg
     8581 cacagtgacc atagacagga tctccccgtt ctgtggattc ataataatca cagaaacctg
     8641 attggccgat ttcttctcca tcacctggag agccgcctgc tgggcgtact gctgcagatt
     8701 cacatccagg ctgatagtca gatcatttcc ggccaccggc tcaatcctgt cctccgccgc
     8761 gttctcaatc tccacccccg ccgcgtcagc cagagtcaaa atcgttccgt tctgtccttt
     8821 cagccactcc tcatattcta cttccaggcc gacgatgccc tgattgtcgc ctcctgtgaa
     8881 gccgagaacg cgggaagcca tctcgtcaaa gggatagtac cgtttatagt cctcgtccac
     8941 cttcactccg gccagtccca tatcgcggat tcgatctcct gtctccttgt ctacattcgt
     9001 cctgataatc tctctggacg tatacttttc taccttcttt tttacttcct cagccggaag
     9061 agaaagctct ctgctgagaa cctccgagac tttctccggt tccttgatct ggttgtggac
     9121 caccgatacg gtgcataccg tcctgttatc ggcaatcacc gtcccgtttc tgtctaaaat
     9181 cctgcctctg gccgccttca gcgtccgctc tctctggtgg agctccgtcg ccatggagct
     9241 gtattcgtct gctctgcagg tcataagaaa aaatagcctt cctgtcaggc ctgccatccc
     9301 aaggcataaa agcccgcaca ggagagctat tctttctctg tgccgtgtcc ttctctgctc
     9361 catactgtgt ctctcctgcg tagaacgctg tcccgattga tacagtatat tgccgaaaac
     9421 acattttatg tattcgtatc cgctttcgcc tctgaaggct tttctgctcc gccgccattc
     9481 ccgctggcag agctttctgc cgcaggagcc tgggacggcg cctctgtgct tccctgggac
     9541 ggcgctgctg tctgcccttc tgggggagca gactctgcag acggatcccc cggcatcagc
     9601 tccggatact ggactccctc ctcgataaat tcttcatcgt atacaggata ggtctcgccg
     9661 ttttcattgg tcggagcttc agagggcgcc tccgtctccc cgttgttctg gctggtgatt
     9721 ccctccggaa gatctgccat ctcctgatcc gccggcgctg tctccccatc cgggaatacg
     9781 ttcatataag gaaggacctc cgccataatc ttgctgaaaa tctcgctggc aaaagtggag
     9841 tgggcctgct cctttccctc cagatgcggc gtatcaatca ccacatagca cagcacctgg
     9901 ggatcgtggg ccggagcgta tccgataaag gataccaggt agttgttggc tgaacgcgga
     9961 tatttctcgg ctgttcccgt ctttcccgca atctcgtagc cctctacggc ggcagctccc
    10021 gctgttccgc cctctcctga taccgtctgg taaagagcct cgttgatgta gtcggaagtc
    10081 tccttggaaa tagtctcccg caccagaagc ggctcttttt tatccaccac agagccctgc
    10141 tcatttaaaa tctgttttac cacatgaggc tggtagtaag agcctccgtt gatcatggaa
    10201 gcataggccg ccgccatctg aatcatggtg cagttatagt tctggccgaa ggagttggtg
    10261 gccagatccg cggatttcat attttccgcc gtgtagatca ggctggccgc gtctgcctct
    10321 cccggcaggt cgatgcctgt cttctgtcca aagccgaaaa tgctctggta cttggcgaaa
    10381 atatccacgc cctccatcct ggaaatattc atcataacta cgttgcagga cttcatcagt
    10441 ccctgcatca cggtagtagg accgtggccc acgattctgg aaacgcagtg gatatcgtgg
    10501 cctccgatag acagaaaacc gttgcactga aacgtctcgc tgtcgttgat aatattctcc
    10561 tccatggctc ccgccaccgt aaaggccttc tggggagaac ctggctcgta cgtatcgttg
    10621 acgcagaaat tacgccacat cttgtaccat gcctccgatt tggccttatc gtccatggcg
    10681 ttaatctctt cctggctgta gtagccgctc agatcgtacg ggttgttcag atcgtaccgg
    10741 gtgctggtat ccatggccag gatctctcct gtcttcggat ccatgacaat agccgccgcc
    10801 acgttgcttc cgatgccagc ctgccactcg tcaatgtatt tttcacatat tttctgaata
    10861 ttcagatcaa ttgtggaaac aaccgtattt ccattctggg ccggtttaat cacgcgctcc
    10921 aggttggaat ccgatgtcag gtagccgtac tctctgccgt tatttcccac cagggagctg
    10981 ttataatact gctcgattcc tccggaaccg gcgcttccgt ccttctgggc gaaaccgatg
    11041 acattgcagg cagtggatcc gttgggatac actctcctgt actcgtcctc aaaccagacg
    11101 cccagaattt ttttctgctc gctgttcttc gtaaaggcct cgtttctggc cttggactct
    11161 gtttcaaact gttccttttc ctcaaaggtc atctgttttt tataccggat ataggagctg
    11221 tccttctttc ctgtgatcgt gctgcgcaga tcctccgcgt caaagccgaa cagctctgtg
    11281 agcagcgcaa tcgtaggctc cacgcactcc tttttctcat cctcgtacat ctgcttcgga
    11341 tcgagaatca gagtgtacac cttctcgctg gtggccaggt aggatccgtt ccgatccaca
    11401 atgtctcccc tccggtaggg aatcgtcctg ctgtcgtaat cctggtggga taaaaccacc
    11461 tgcgtatagt cctcgttctt gttctgcacc atggtataga gaatcacggt aagagcaatt
    11521 aaagccagca tcatcaccaa gacggtaatg gccagctttt cctgcatgta ttttctgaat
    11581 ggctgcttat tattagtgct ctgggacatc ttcatactgt cttacatact cgctttctgt
    11641 tttatcatac aaaagaatct gatccttatt cgcataaacc atccccagtt cctttgtagc
    11701 aacgtcgtaa atgtaatcca gatccacgta ggtattgatg ctcgtctcca gcgcatcatt
    11761 ctcggcccgc agcgcctcca cctcacgttc cagcttctca atatttccca gacgggaggt
    11821 aatggaagat cggagagcca gatactgcat acagatagcg agggtaatta tcgctgccag
    11881 agtcagcgcc atcacgtagg gcgcgtccat ctgcagggcc ttctccctgt ttctccttac
    11941 aatatggctg cgcctgagat gatcctcagc ctgcctcttc ctctgcgctg cctcgcggct
    12001 gccagaccgg cccttcccgg cctgctttac ttttctaact gtattcccat ccgtatatgt
    12061 atcatatact cgatgccttt ttgcagccat aggtcctcct cctctttttg cagggcgtct
    12121 cctgcagcgc tgtctgcgcc gctatgctcc tgccttttca aatactctca gcttggcgct
    12181 ctttgatctc ttattagcgg ccagctcctc ctccgagggc agcacaggct ttctcgtcac
    12241 tacccgccct ttgctctttc tgccgcacat gcacaccgga aactccggcg gacagatgca
    12301 gggattttca ttttccctga acttgttctt tacaattcga tcctccagag agtggaacgt
    12361 gataatcgac aggcggccgc ctggattcag cagatcgatc atcgtatcga tggactgctc
    12421 cagcacctga agctcgcggt tcagttcaat ccggatggcc tgaaacgtcc gcttggacgg
    12481 atggcctccg gtggctctca ccttggcggg aatcgccgcc ttaatgatct ccgtcagctc
    12541 gccggccgtc tcgatctcct tttcctgtct ggctttcaca atatgctttg caatattctt
    12601 ggcaaagcgg tcttcaccgt aatctctgat gatgcggtac agctccatct cgctgtagcc
    12661 gttcacaata tccttcgcag tctgagtatt tctctgatcc atccgcatat cgagaggcgc
    12721 gtcgtcctcc cggtaggtaa agcctctgtc agccgtgtca agctgatagg aggaaactcc
    12781 cagatccagg tagattccat ctgctcccga tatcccctgg gacgctaaag cgtcctttat
    12841 attctcgtaa ttcgtccgga tcacagtaac ccggtctccg tattctttca gtctctcccc
    12901 ggctgccgca atggcatccg cgtcctggtc aaggccaatc agcctcccct gttctcccag
    12961 ccggctcagc accagagagg catggcctcc tcctccgaga gtgccgtcca cataaatgcc
    13021 gtcaggcctg atattcaggc tgtccaccgt ctcgtacagg aggactgatg tgtgtgaaaa
    13081 tgtcatatcc caagtccctc catattctcg gcaatatctt ccatgtcatc atagacattc
    13141 ttctcttccc agagctgccg gttccatatc tcaattctgc ttcccactcc cgccagcact
    13201 acttccctct caagatgggc gaaatttctc aaaacggccg gtatcagaac tctcccctgc
    13261 ctgtccacct cgcagtccga agcgcccgcc aggaagaaac gtgtaaattt tctggcattc
    13321 tggttcgtca gcggcagggc tctcagcttc tcctcaaagg cagcccactc ggcattgcca
    13381 tacacaaata aacagccatc gagtcccttt gtcacgacaa actcatctcc cagctgttct
    13441 ctgaacttcg agggcacaat cagacgcccc ttcccatcaa ttgtatggct gtactctccc
    13501 ttaaacatag aaccacctgc aggctgacgc cgcctggctt ctgcggaact ccacacagcc
    13561 ccactttccg ccactttcta ccactttatg ttataatact agtacatacg cagaaaaata
    13621 gcaaggcatt tttcaaaaaa attatgtaaa ttaaaacctg caaaactgcc ctgaggcgtt
    13681 ttctgtacaa acaaaaaaca ggcgccgcca tatcggcagc gcctgcgcgt taatatcctg
    13741 ctacaatata ctgattcagc agctgatcca gctctacgct gtagcggtaa atctttctgt
    13801 attcctcccg ctgttcaatg cactgatcca tctttttgcg aattttctca atttgctcca
    13861 ctaactcttc tttcgcattt gccatcgcta ttctcctttg atccctgttt ttaactttga
    13921 tcgtttccag atgatgacgg ctgatgctgc agccactaaa accatggaca gagcctggga
    13981 taccggaatt cctgtgccga aaaataaaag ctgatccgtt ctcagtcctt cgatccacgc
    14041 gcggccaagt ccatatccca aaagatacat ccacaggatt tctccatcaa atttttttct
    14101 tttgcggtac cacagaagaa aggcgagcac tcccaggttc cagactgatt catagagaaa
    14161 cgtcggatga acctgaatat actccactcc gttttccaca attctgtggt ctaacagctc
    14221 ctgggaaatc atggaaggat tcaccaggga catcttaagt ctcatggcca gcaggctgtc
    14281 cgtatagcct ccaaacgcct cgcagttaaa gaagtttccc cagcgtccga taatctggcc
    14341 tgtaatcagt ccgatgcacc cggtgtctgc catcgagaaa aacgaaacct tccggacttt
    14401 tgtaaacaca atcagagtca ggactgcgcc gatgattcca ccgtagatgg ccaggccgcc
    14461 gccccgcagg ttgaaaatct caatggggtt gtccttataa agctcccagt caaaaatgac
    14521 atagtaaagt ctggctccta tgatggaaaa aataatcgca tacagcgcaa aatccagata
    14581 aagctccgga tcctgccctc ttctgcgggc gtctttctgc gccatataga gtccggccag
    14641 cattccgatt ccaatgataa tcccatagaa agcaatctca aagcctccta tggagatact
    14701 gttcctcaga tgctcaatgg ttataccaag atgcacaaag cttacatctg cgccttctgt
    14761 catataagct ctcctttcga tgtaactttt attttaagtc acgtttcaac aaaaatcaaa
    14821 cacattctct cgacattctg ctctcttttt cgacacgaaa ttccatcttt tagccaattc
    14881 ccttgtaggc aattcccaga atgaacactg cgatggtgag cgggacgtaa agatacttag
    14941 ccagagcgcc gaaccaggcc ggaaccgcag cctttcttcc ctcagacagc tcctccttga
    15001 ttttcttata tccgaataca tagtagacgg aaacggctcc cagaaccgct ccaaagggca
    15061 ccacgataat ggtgataaag tccatccatt ttcccacaaa cggttccggc tccaggaaaa
    15121 tgcctacgcc cagacagatg gctccgcaca gagccacagc cagacggcgc ggaatctgga
    15181 accggtgctg ccagctctca atcaccgcct cgaacatgtt aatcagggac gtaattccag
    15241 cgaacacgac agacaggaag aaaatcactg aaaaaacctg tcccatgggc atctgggaaa
    15301 aaatctttgg aattgtgata aacattaagg ccggaccgga accaggctcg atgccgaagg
    15361 cgaacactgc aggcataata gccagagcgg aaagaagagc cgcgatggtg tcgaacactg
    15421 ccgtccgcat ggaagcgccg ataatatcgg cgttcttatt taaataggag ccatagacaa
    15481 tcatgccgga tcctgtgatg gaaagagaga aaaaggcctg tcccatagcc attacccagg
    15541 tatccacatt ttttaactgc tcccatttgg ggacaaacag aaagctgtag ccgccctccg
    15601 ctccatccag aaagccgact ctcaccgcca gagcggcaaa caggatgaag aataccggca
    15661 tcataatccg gttggccttc tcaatctgag ccactgaacc ggtcagcagg atcgccactg
    15721 taatcagcac aactgccaga tgccatggaa ggcttccaaa gcttcctgtg gcctgggaaa
    15781 aatattctgc tgaatcggta ctcagaatcg ttcccgtcag agaacctccc agagagcgga
    15841 gcacccagcc gatgataatg gaatagccga tggcgattcc taacgatccg attaacggaa
    15901 tccagccaat gatccgccca attccttttt tccaggccgg agcgtcctta tcgtcccctc
    15961 cccagcacag ctcgtaggag ccaagcgttc ctgttctggc tcttcttcca atggcaaact
    16021 cggctgacag ccctgtcagg ccaaacagca caataaaaaa aatgtatggc accaaaaatg
    16081 ccgcacctcc gtattgccca agacggtatg ggaacatcca gatatttccc aggcccaccg
    16141 ccgagccaac gcaggccagt acaaagccca gcgagctgct gaagcttccg tttttgtgac
    16201 tcatctaaaa tttcctcctt tgctactccg ctttaaatca ttaaatcgac cgcggcagtc
    16261 tacaatacct cgatctctta tcttaatata ttgggaaaag aaaagcaaac attttctctt
    16321 ttctttccct ttattctatg atatccttat tacatggcat cacacagcat cttcgcagga
    16381 aaggcagacc gcctcctgtg tgctgacgtt aagctgaagg aaggataaat actatgaaat
    16441 taggaattgt gggtttaccc aatgtaggaa aaagtaccct gtttaactct ctgaccaagg
    16501 ccggagcaga gtccgccaac taccccttct gtaccatcga tcccaacgtg ggcgtagttc
    16561 ccgtaccgga cgagagactt cagaagctgg ctgcgctcta caactctgcc aagattacgc
    16621 cggctgtcat cgaattcgta gacatcgccg gactggtaaa gggcgcgtcc aagggagagg
    16681 gccttggaaa ccagttcctg tccaatatcc gcgaggtgga cgccattgtc catgtagtcc
    16741 gctgctttga ggatcccaat gtcgttcatg tagacggaag cgtaaatcct ctccgcgaca
    16801 ttgagaccat tgacctggag cttatcttct ccgacatgga gattctggag cgccgcattg
    16861 ccaagaccac taagagcgct atgggaaata aggctcttac aaaagagctt gagatcttaa
    16921 aagccatgta cgcccatctg gaggaaggca agttagccag aagctacgag acagaggatg
    16981 aggacgagct ggcatttatc gccactttaa accttctcac ctggaagcct gttatcttcg
    17041 cagccaatgt agcagaggat gatttatctg acgacggagc gtccaacgag tacgtgcagg
    17101 cagtgagaaa tttcgccgct gagaacggca gcgaggtatt cgtcatctgc gctcagattg
    17161 agcaggagat cgcagagctg gacgacgacg agaagaagat gttcttagag gatctgggat
    17221 tgactgaatc aggactcgac aagctgatcg cagccagcta ccgcctgtta ggccttatca
    17281 gctacctgac agctggagag accgagacaa gggcatggac catcaaggta ggcaccaagg
    17341 ctcctcaggc agcaggaaaa atccactctg actttgagag aggctttatc aaggccgagg
    17401 ttgtcaatta tcaggatctc ttagactgcg gaacctacac agccgccaag gaaaaaggcc
    17461 tggtccgcat ggagggcaag gaatacgtgg taaaggacgg ggatgtggtt ctcttccgct
    17521 tcaacgtata atttataaat aaggatctca aaatccccgg cgctgccgtc ctgtcacaga
    17581 catgcagcgc cggggatttc cttttgcttt ctattctgac tttctaagcc gcagctcttc
    17641 gctgccgcct ctgtgccgcg aagaagcttt agtcgtctaa ctcgtcctcg cttaccagct
    17701 cgtcgtactc ctgctcgtct aacagctcgt cgaaagcgtc agccacgatc tcgtactcgt
    17761 catcgtcctc gatgttctcc agattcggag ctccattctc gtcctctgtg tagcggtaca
    17821 gataaacctc gccctcctcg ctgtcctcgt cgtccatcgg aagaagggca atatactcct
    17881 tatctcccgc agggaagatt gtgaggacta cgcactccag ctctcttcca tcgtccagag
    17941 tgagggtgac tgtcatctcc tcctcatttt ctgcatccgg gtttacgttc ttgttctcag
    18001 ccatagcgtt ccttaccttt ccatatttta tcggtgtaca ctaatgctat cagagacaac
    18061 cggaaaaatc aagtaaattt ctcattttcg tcatccgcct gattttcctc tccgcgctct
    18121 tcctgctcct cctcagcggc ctcgtttctg tagccggcca tctgctccag agtcgtcctg
    18181 gaaacggctt ttttcgagaa gtagacgctc atagcccggt tcagcttcac cgtcatagac
    18241 gcctgtctgt taaacagaac ataaatgcag aatactgcct cgaaaaactg catggccatt
    18301 cctgcgatca tggtaaatat cacagccgcc gccaccgctc cgggcgccgc cgctaccagc
    18361 cacggagcgt tgctcaaaag tcccgctccc ccgattccaa ggccgattgc cctggccgcc
    18421 agcattaaag cagctactcc ccatccggac tgcaaaagaa gggtatacca gaaataaaac
    18481 acggccgtac ttaaaagatt taccaggcct tctgtcacat ccagaccgca cagcgcgcac
    18541 agacctatgt aaaacaggct gtatatcact ctcactcctg taaaaatttt gacaaaagta
    18601 tacagcttct cacgctcgtc ccggtagcct ggatactcct cgtccatccg ggtaatgtat
    18661 tcctctccca tctcgtaggt aatcaggcgc atctgcggcc tttgtcttct gttcatgttt
    18721 ttctatcctt tcccgcgtca gaactctatt cctcgtctgg ctcctgttcc ctgctcaaac
    18781 ggatgctttc tgcacagaat ctccgacaca tagtctgcgg cctccgtcat cctggcagac
    18841 ggattccgtc ccgtcaggac tgtctccaga ttctgcggcc ttttttccag gaaatccagc
    18901 acctgctctt cctccacaaa cccgtttccc acagccgcgg ctatctcgtc taaaataaga
    18961 agagcctgtc cggctttggc gcaggcctcc cgcgccaggc tgacggccgt ttcaaacagc
    19021 ccgctgtagt aaagagcggc ctctttcttt tcctcccgcg tcatctgcca ggtaaagcca
    19081 aaggtctttt tacagggaat caccgtaatt cccggaaggt tcttaagggc tcttacctcc
    19141 cctgaatcgt ctgtcttcag aaaccgggca atcaccacag gataaccgca gccctgcatt
    19201 ctcacggcta ggccgacagc cgccgtagtc tttccttttc cgtctccgca gtaaagatgg
    19261 acacagttca tatttcctac cattcctttc cgtcctgctc ctccagatac tcctccacaa
    19321 atctggaaac ctccgccggc ttgtgatatc tgttttttac gccgtacacg tgaagacgct
    19381 gcttggccct tgtcatggcc acatagaaca ggcgtctctc ctcctcgatg tcagcgtcca
    19441 gcaccgcctt attgtgaggt gtgacgcctt cgttggcgtc cagaatgtac accacccggt
    19501 attccagccc tttggaactg tgcatggtgg agagcatcac cgcatccgcc tgctcctccc
    19561 gctctctggc ctgccttttc agctcttcgc cgtaggcccg gatatgttca aaccaggcgt
    19621 cgaaggtctt atatctggcc gcgctctccc tgagctgctc cgctgtctcc aaaagctcct
    19681 ccgctttcac atggtgggcc gcggcatact cataaagcca ggcatcgtag ccgatggatt
    19741 tccggatata attcactgcc gccagggggg acatgcggct gactgccgtc agatcgaact
    19801 ccaggttctc aatgcgctcc accatccagt ccttatcttt ataataggcc ttcagctgtt
    19861 caaaagacac ctggggatct ctcagcgcgt cacggcccac atacctggcc ggccggttga
    19921 tcatctggag cacctctgcc ctgtctctgt ttcccagggc tacccggata taggacagaa
    19981 tattctggga aatccagtgt tcatagagat tgggaacctg atctctggcc cgaaaaggga
    20041 ggttgtgctc catcagcttc tcaatcagcc gcttaggccc ggagtttgtc ctgtacagga
    20101 ctgcgatatc gctgtagctg caccctgcct ctgcatacat cctgatttcc tccgcaatgc
    20161 ggctgttttc ctcttcctcg tcctcccaga ttctcgtgat cacgcctctt cccctgctgc
    20221 ctgctgtttt taaagacttc ttaaaccgct tttcgttgtg ctcaatcagc cgcagagacg
    20281 cctccacaat ctccctggta gagcggtagt tcacatccag aagcactctt gccgccttgg
    20341 gataatctct ctcaaagccc agcatgatct ccggcttcgc tccccggaac cggtaaatag
    20401 actggtcgtc gtcccctacg ataaacaggt tgtccgaagg ggcggctaac atccgcacaa
    20461 tctggtactg aagtctgttg atatcctgga actcgtccac cagaatatat tcgtactttt
    20521 tctgccaggc ggacagaata tcgggacgtt tgcgaaacaa atcccagcac ataaccagca
    20581 tatcgtcaaa atcaatttta tgggcccgct gcagctgttc ctcataccct ctgtagatcc
    20641 tccggaagga atccccggag cagcttttcg catagtaatg ctccaggtca atctgctccc
    20701 ccttcaccgc gctgatctcg ctgatcaggg aggaaatcag ttcgttttca tcctccggct
    20761 ccagctgctc cttcgccgtc agctcccgaa tcagcctgag cttctgatcc tctcttatga
    20821 tatccgacgc atcgtactga taggccagct tcaggatcct gaaaaagacg gagtgaaagg
    20881 ttccgaagct tacctgtcct cgcataggcc ttccttccat cagccgctca aaccgttcct
    20941 tcatctccct ggccgccgcc cgcgtaaagg taatcaccaa aatggaggag gggttcaccc
    21001 catgcttctc aatgagactc tgaacccggt gggtaaccac agtagttttc ccggatcccg
    21061 gtcctgccag aaccatcata ggaccgtcct tgtggctgac tgccgcagac tgcgcttcgt
    21121 taaatggcat gctctaattc ctcccaagac gcgccccgcc caagggcatt tatacatcgt
    21181 ttcccactga gataaaaggg aggatgccgc ggattttccg caggacatcc tcctggcagc
    21241 agcttctact tctccagaag ctcaattccc tttctaattc gctctaaaga ttcctctttt
    21301 cccagaacct ccataatctc tgtggctccg gccggagtca tctgctttcc tgacacagcg
    21361 gtgcggatcg gccacatcac aaatcctgtc ttcacgcctg tctcagaaat gtaggcggac
    21421 agcctctcgt agagggcgtc gttggagaag tcctcctgcg cctccagaat cggaagcacg
    21481 tcctttaaca ccttcagaga cgtctcctct gtggatttca tcttcttgtg aacatacatc
    21541 tgcggatcgt attccggaag ctcctcgaag aaatcaatat ggcctgcaat atccgggaat
    21601 acctcgattc tcgtcttcac catggccgca atctttctca gatccagatt cttcttgatc
    21661 acctctctga tatacggctc agccatctca taaaatttat cgaaatccat ggatttcatg
    21721 tactcgccgt tcatccagcg cagcttcacc atatcgaaaa ctgccgggga tttgctgata
    21781 tggcggtagt cgaactcctt aatcagctcg tccagggtaa agagctcctg gtttccttcc
    21841 ggagaccatc ctaaaagagc gacaaagttg accactgcct cggagaggaa gccctgatca
    21901 atcagatcct ggtaagagga atggccgctt ctcttgctca gcttcttgtg ctcctcgttg
    21961 gtaatggtgg ggcagtgtac ataaaccgga acctcccagc caaaggcctc gtagaggcgg
    22021 ttgtacttgg gggaggaaga cagatactcg tttcctctta ccacgtgagt aatcttctgc
    22081 agatgatcgt ccaccacatt ggcgaaattg taggttggga agccgtcgga tttaatcaga
    22141 accatgtcgt ccagctcaga gttgtccacg ctgatgtctc cgtaaatctc gtcgtggaac
    22201 gtggtcgttc cctctgtcgg attgttctgg cggataacga aaggctttcc tgccgccagg
    22261 ttcgcctcta cctcctcctt ggacaggtgc aggcagtgct tgtcataggc cataatctcc
    22321 tcgccgttta ctgtcttctt caggctgttt aagcgctcct gatcgcagaa gcagtagtaa
    22381 gcctctccct tgtcaatgag ctccttggca tatttcatat aaatgccgga cttctggcgt
    22441 tcgctctgga tgtaagggcc taccggtcct cccacatcgg ggccttcatc gtggatcagg
    22501 cctgtatcct ttaacgtatt ataaataatc tcagtggcgc cttccacgta gcgctcctga
    22561 tccgtatcct caattcgtaa aatataatct ccgccctcat gcttggtaat caggtaggca
    22621 tacagcgcag ttctcagatt tcctacgtgc atctttcctg tcgggcttgg ggcatatctt
    22681 gttctgatct tttccatgac tccacactcc tcactgttag aataaggccc ggccggctgc
    22741 cgggcctgtg ttaaagataa ttcattatat cgcttaatct gaaaaattac aagtctaggc
    22801 tgccatgtcg agaagacggc aggcaaaatt aaaataaatt acaagactgc aggcgtccag
    22861 aatcgtagag atcataggag acgccatcag cgccggatcc atgtgcagaa ccttggcaat
    22921 aatcggcagc gtgcagccaa tcgtcttggc aataatgaca atgcagaaaa tactcaggac
    22981 aacagtgaga cagatcatct cctgtcccgg ataggataag gtcagacgca caaagttggc
    23041 aatggccaga cagattccca ccagaatgcc cacccggagc tccttccaca ctaccttcgc
    23101 caggtcggag gggctgatct cgcccaccgc catgcctcgg ataatcatgg tactggcctg
    23161 gcttccggaa ttaccgcctg tattcatcag catgggaata aaggtaacca gaagaggaac
    23221 cgctgagaaa gcttcctcat aagtagtcag aatttctcct gtcaccatgc tgctgaacat
    23281 aagaatcaac agccagacaa ttcggttctt ggccagctgg aacacgcctg ttttcagata
    23341 tggcttctcg ctgggattca tggcggccat cttctcaaag tcctctgtgg cctcctgttc
    23401 cataacgtcc atcacatcgt caactgtgat aatacccacc agacggtttt ctccgtccac
    23461 aacaggaagg ctcagaagat catactcatt aaacagatcc gccaccgcct cctggtcgtc
    23521 cgtcgtgtgg gccttcagca catggctgtc cataatctcc tcgatggtgg tggcatacgg
    23581 gctcattaaa agatccttca ccgtcaccac gccctccagg tggcgtcccg catccatcac
    23641 ataacaggta tagatagtct ccttatctac tccgtacttc cggatgtatg caaacgcctc
    23701 ctccactgtc atggccttct tcagccccac gtactcagct gtcatcacgc ttcccgcgct
    23761 gttgtccgga tacttcagga actggttaat cagctttctc gtatcagggc tggaattttt
    23821 cagcactctc tttacaatgg tcgccggaag ctcttccagc atgtccaccg cgtcgtccac
    23881 gaacagatcg tccataatat actgaagctc attatccgta atgctggtaa tgatgtgctg
    23941 ctgcttctcc accggaaggc aggcgaacac atccgacgcg atttccttgg gaagcgtccg
    24001 aaacactacc accgttttct ccgaatccag ctcctccata aacgaggcga tgtctacctc
    24061 gttcatctct atcagttttt ccttcaggct tctatactgc ttctcatcag ccaaagcatg
    24121 aagctcgtca aaattcatct cctccatact ctactccctt tccaaaccgc gcactcgctt
    24181 cttcctatta tagtaaggat ccattaaaat ttcaatggat ttatacgaga taatagtagg
    24241 gcagaaagaa tttagccgca gctgacgccc agggaagaaa catggacaga tcgataaata
    24301 cagggcagag aatcaggctt gccgacgcaa aaaacggaat caggcaggca accgccagcg
    24361 gatttttcac aatcctgcaa agtccccagg aaaacagcgt gcacattcct ccataaacaa
    24421 tcagccggat cccctccagt atccaggaag acgaggacag ctccccggcg gctgcaagcg
    24481 ctgcgaatcc gctgacgcag gacagaaaca caggggccgc cagacaggag aaaacggccg
    24541 cctcacgtcc aaggcctgac agggtggaaa acagacctct cttttcatcc tcgcagaccg
    24601 tcactgccgc cgtcaggccc atcacaaaaa taaacaccgc cgtcaggcct ctggctggga
    24661 acgtctgctt catagaaggt tttccaagct gcgttccctc ttccgtctca tactggaagg
    24721 caaaggtgct tccattttcc agataatgat catacatagg ttccagcctc ttccagacct
    24781 ctttctctcc ctgaaaaact tctccctccc tgctgtacgt ctccagaagg ctgcgtcccc
    24841 atacggtaaa caggccggaa aatacgactt cagaggacag cttgtccaca gctgtggaag
    24901 gagccgtcac cagagtaatg cttctcttaa accgcccgct ctccagtttt tccagcaaat
    24961 cctctgagaa aatatagccg cactctgctc ttctggcggc cacatcctcc cgcagttcct
    25021 cttctgaact gctcaaataa aactcaaagg agtgctctcc tgacagcagc tcgtcagcta
    25081 cgcgccgatt ccagtctgac tctcctgcgt agagggcgat ggcaatggca tcctcctccg
    25141 gacgctctgc ctcccgaagc agccagagcc ctgccggcag ggcgagcagc agaagcagga
    25201 aaaaaaggcg ttttgtctgc cgcttcaaag acagataaaa ccacagtccc attttattca
    25261 taagccctcc tcactgccgc cgcaaggcag aacgccgccc cttccagaac aagaagcctg
    25321 agaaccggag cccatgccgc cagctgcccg gcccttcctg acatatcttc tgagaccatc
    25381 catttcaccg cttccatcag aaagaagacc ggcgtaaatt tcccggctcc ggcagccgcc
    25441 tcaggcagaa aaacagacgg aatcagcccg ccagccataa acatcatgac aatcgtggaa
    25501 agaaagagaa tgctgacgcc ggccagcgtg ctccttcccg cctcgtaaat gagaatcacc
    25561 cagccggacg cgcagacgca gacgagaagc cacacaggaa tgctgaacag accgctctga
    25621 aaaaagcctt tgacaaagca gatgaaaaat ggaactgccg tagccagagc aaacagaaag
    25681 gccagcgcag ccgttctggc ccacaggcgc ataggacggc tgaatccaga aagatacagc
    25741 tttttttcca tcacagggga aaaggaacgc agaaatccag acgcaggaat tcccagaaga
    25801 agaactgcca gcacagcgca ggaaattccg taaaacacct ctgtggtcac atctcccgat
    25861 gcgctcacct gctccgtttt aaaatagaca gagcgggaaa gggcatattt cagatacatc
    25921 tggttcagat ctgactctgc ctgcggaatc tggccggttc ttcccatatc ccctaagagc
    25981 tcatctgtgc tataaacagc ggcctgggca gtctttaaaa tttctgttcc cgcatctgtc
    26041 agttcccgga aaatcgaagc ttccagcccg gcctgctctg gaaatacaat cgtcacagga
    26101 tcgttggtcc cgttcataat tccctccagc agctgatccg gtatcagcat aagggcgtag
    26161 atcgccccct tctccatctg cctgcgtcct tcctcctcgt ccagatagac gaattcacag
    26221 aggctggaca cgctctccag agaggacacc atagacatga tccattttgc gccgcgatcc
    26281 gcttcgggca ccgccactcc tacctgaatg cttcccacag actgctcccc gtaaagcatc
    26341 ctgtttgcag aaaaagcaat tgtgccggct aataccgcca gcacaactgc tcctgccaga
    26401 aaatagggga ggctttttaa cgccctcttc atctcaattt ttaaaatcgt caaaaatcgt
    26461 cccatgaaat tctgttatcc ttttctttag ctgaggccag ctccgctcag catggaggta
    26521 agtcccatat acagttccat aatcaccgta ttccactctt cctctgtagc tgccagaata
    26581 tcaaaggatt cgccctccgg tttggaaacg gcctcctcta aaggcttgat tccatagctt
    26641 ccagacagct ctgctaaaag catgccctcg tctgccggac cggctgtcac tctcagagag
    26701 tcaactaccg cgttgaagga ctcgcctgga accagatcct ccataatacc gtctatgcgg
    26761 atgcttccaa cctccgtgtc attctcctct gcgtaagcgt caatggtgta attggctgtc
    26821 ggaatgtcgt actcgccgct catgctgaag agcatcttct cgcctgccgc ctctacctga
    26881 agcgccagct gggcctgata gagcttatcc ttttcgtact ctcccatttt agccatgtcg
    26941 atgacaatct tctcgccgga cggctcctcg gctgtaaggt tcgcctctat attcgcggtc
    27001 tggctgtagc cgcctctgaa gtttacagtt ccgtacagct tcaaggtatc ggctgcctct
    27061 gcagacgccg ctgattcctc ttctgcagcc gctgtctcag cctctgccgt ctgatctgcc
    27121 agagaaagct ctgtactgta gtcaaaggac gccagttttc cgtcatctgt cacgtaaact
    27181 gccagagtaa cgtctcccat agctcccttc agctgggaaa gaagcgcctc aacctcctca
    27241 tccgctgagg tccaaagctc tgtctgctgc tgttccggag tcatatccgg gctctccatg
    27301 ccgtaaagct gagccatctc ctcagagccg tacagggacg cgttcagatc gtaaaccagc
    27361 tccaggtagg taatcatatc cttcttcaag gtttcatcag ccaggaagaa gtcttttgtc
    27421 tctgtgaaga actgaacaag ggcagcgttg ctgagaacta cgtcgtatcc gtcgcactcg
    27481 acctctgcgt ctcccactgg gcagcttttg ctctcgccct tttccactgt catggccgct
    27541 ttcagattat ccacagcctt gcttcctgtc ttatatctgt cccagagtgc gccgaaatca
    27601 aacataggag tctctgaatg ggacagctcg ttggccttct tcatatagtc ggcataagcc
    27661 tggagatcca ttcccatgtc gcttaagctc tttccaagat acggggagtt ggcaatctgg
    27721 gtattcaaat cctcctccag attcagcgta aataccttgt tcgtcatatc cggcggcagg
    27781 gcaatggcca tctccgaatt atccaggtaa aatttcgcgt tgaacatagg aatgtcgccg
    27841 tactggaatc ccagatccat atccatggta ctgctgcttc tgtcttccct ggcattgata
    27901 ctgaagcccg ttccctgaag ctctgaactg cctaacagct cccccagagt cagattcatg
    27961 cctacctggt aggaatcgct gtacagcttc tctcccaggg ccttccatcc aaaaatctcc
    28021 tccatgggat cggtctgtcc ttctgccact acgcccttaa atgcgtcaat gaccacatcc
    28081 ttgggatccg gcttattcat ctgccagaac gccacgccgc cgaccactgc cacggctgcc
    28141 gcagcagctc cggccatcca tatcttattg ggctttttct ctgccacagc cagctccgcc
    28201 ggctctcctg cagagccggc ttctgtctgg ccgctctggt tctctccgcc tgccgctcca
    28261 ttcggctcag tctcgtttga agcttccatc agattctttt tgcatacggg gcactcagcg
    28321 ctcccatctg gaatttcctg atcacaataa gggcatttca taccgttttc ctcctcttgt
    28381 ttagatgaag tttattctaa catattttcc caatttcgtc atcagattag gcaattttgt
    28441 aaagaatctt taagaatttg gacgggtttt gtcagaattt accaatcagt ttttccggtt
    28501 ccaccccgtt ttctatgctt tcaggaatca gcactccctc ctttaaaata tacagcgcgc
    28561 tgcaggcctg aagctcaggc atctcatggg aggtgaggat caccgttcct cccccctgtg
    28621 taaaggtgcg aatgtagtga agtatctcct ccttcgcccc cagatcaagg gccgctcccg
    28681 gctcgtccat aatcagaaga gacgcctgat tggagagggc cgccgcaata ctgagacgtt
    28741 ttttctggcc gcctgacagc tttccagccg gaacgtctaa aaattgggag atccccaatg
    28801 tcttggccac tccctgttcc agatccctct ccattttctt tttgtctccc ctgtaccaga
    28861 gggcaaaatt gtctctggcc gtcagctctg gaatcagagg attttcctgg ggaacatagg
    28921 ccgccctttt ctcaaagaca gaacgccttc ccacagcctc ttccccgtcg aagcggatac
    28981 ttccctgatc cggccggctc acccccgcca gaattgataa aagcgtcgtt tttccgcatc
    29041 cgttgccccc ggcaatgcct acgcactgtc ccggaaccgc cgtaaatgac gccccattta
    29101 aaatctggcg tttcttaaat tttttgtaga ttcccgatac ttccagcata cctgtcctcc
    29161 tgtttaaaaa agggccgctg taaaactgtc tttctgtttt acagcagccc tgtcaagcct
    29221 actctttatg agcttcctga ttcagatcgc ctggtttcat gctcaggtta atgcggccca
    29281 tcttgtcaac ctcgataacc tttaccgtaa cctcgtctcc gatatttacc acatcctcca
    29341 ctttcgccac tctcttatca gaaagcttgg aaatgtggat cataccgtcc ttattgggag
    29401 ccagctccac aaaagcaccg aaattcataa tgcggacaac cgttcctgtc agaatctgtc
    29461 ccggctcaat ctctgtgaca atgctcttaa taatagaaat ggccttgtcg atcatagcct
    29521 tatctgtgcc gcagacggaa acgcttccgt cgtcgctgat gtcaatcttc acgcctgtct
    29581 gctcgatgat cttgttgatc accttgccct gctttcctac tacatcgcca atcttctgag
    29641 ggtcaatggt aatctgctcg atcttcggag cgaactcgcc tacctctttt ctaggctctg
    29701 caataactgg tttcataatc tcatccagga tgtaaagtct cgcctctctc gtcttggcga
    29761 tagcctcctc gatgattggt cttgtcaggc cgtgaatctt aatatccatc tggatggagg
    29821 tgattccctt gtgagttccg cctaccttga aatccatgtc tccgaagaag tcctctaagc
    29881 cctggatatc tgtcagtaca atgtaatcgt cgtctgtgtc tccagttaca aggccgcagg
    29941 aaattccagc taccggagcc ttgatcggaa cgcctgccgc catcagagac agggtggaag
    30001 cacagatgct ggcctgagaa gtagatccgt tggactccat tgtctcagaa acagtacgga
    30061 ttgcgtatgg gaactcctcc tcgcttggaa gtaccggaat taaggccttc tcagccagag
    30121 cgccgtggcc gatctcgcgg cgtcccggtc ctctggacgg ctttgtctct cctacggagt
    30181 aggacgggaa gttatagtgg tgcatgtatc tcttgcttgt ctcgttctca tccagaccgt
    30241 cgatcttctg agcctcagac agaggagcca gcgtacatac gtttaaaatc tgagtctgtc
    30301 cgcgggtgaa cataccagag ccgtggactc tcggcacaat gtcgatctca gctgccagag
    30361 gacggatctc tgtgatgccg cggccgtcag gacgcttgtg atcctttaag atcatctttc
    30421 tgactgtctt cttctggtac tggtaaactg cctcgccgag gactgccagc cactcctcgt
    30481 tctctgcaaa agcctcctcc agacgctctg tgatagcctt gatgttctct tctctcttct
    30541 gcttctcgtc tgtgaagact gccgcctcca tctcttcctg gggtacaatc tccttgattg
    30601 ctgcaaataa ttcctccgga actgcgcagc tctcgtaaga atgcttctct tttccgcact
    30661 cagctacgat tgtatcaata aatttaataa tatcctggtt tacctcatga gccttaaaga
    30721 tagcctgaat catcacatcc tcaggaacct ctttcgctcc ggcctcaatc atgataacct
    30781 tctctctggt ggaagccact gtcagagcca tgtcggaaat ctttctctgg gctgcagtcg
    30841 ggttcacaat aaactctccg tcgatcatgc cgatctgtgt ggtcgcacag ggaccgtcaa
    30901 acggaatgtc agagatgcag gttgcaatgg cagagcccag catagctgtg tactccgggc
    30961 tgcactccgg atcaacggac agaaccaggt tgtttaaggt aacgtcgttt ctgtaatcct
    31021 tcgggaacag aggacgcatc gggcggtcga tgacgcgggc agtcagaact gcgttctcag
    31081 acgcctttcc ctctctctta ttaaatcctc ccggaatctt tccaactgcg tacatcttct
    31141 cctcaaactc tacgcttaac gggaagaaat caatgccgtc tctcggctta tcggaagctg
    31201 tcgctgtgga cagaaccgtg gtatctccat aatgcataaa cgcagcgcca tttgcctggg
    31261 ctgccactct gccgacgtct actgtcagtg ttctgccggc cagctccatt gaaaaactct
    31321 tatacataga aaggtctcct tttcaaattt ccttgttcaa aaactgttgt ctcctgtttc
    31381 ctctccctgc ctgccaaatg gcagagggaa cctgcggaag tatccgaaac tactgatctg
    31441 ggcgcagaac ctgccggata tcaaaagcct tcccggctct cctcctgtgc ctacatcagc
    31501 ggtctcggat cacgtcttcc acagaacctg ttgtcttctg ccggaaacga tgtttcctga
    31561 tgagcgtaaa taattagggt ggatttctcc accctaatgt cattcattac tttctgatgc
    31621 ctaacttctc gattaaagca cggtatcctt ccagatctgt cttctttaag tagtctaaga
    31681 gaccgcgtct ctgaccaacc atctttaaca gaccgcgtct ggagtgatga tccttctggt
    31741 ttgcctttaa gtgctctgtg agctctgtga ttcttgctgt taagatagca atctgaacct
    31801 ccggtgaacc tgtatctcca ggctttcttc cgtactcagc gataatagca gactttttct
    31861 cctttgaaat catggtgatt tcctccttat aataaaaata attcttaccg tgcaccaagc
    31921 ttctgtcagg aactcaaaaa gctgagcgcc ggcgcgtttg tacgtcatag agtatagcac
    31981 atgattttct ggttgtaaat cagtttttca ctgtttttct tctgttttat tcaccgtccc
    32041 accgtctctc ccagattttc ccgattcccc acagaccgat gaccagaatc gactctcccg
    32101 ccacggtaag ggatacaacg gaaatcatct ggttcagcct ttcaaagtcc tccatcagaa
    32161 tgcagaacca ggtaagtccc atagctccag acgaagccgc cagctctgca agcatggctg
    32221 ctgtgagagc cctccgccaa aaccgctttc tctttataag gaagtatatg gaggctgaaa
    32281 ctgctgcagc cgctcctaat acgcctgctg tcagcacaaa aagcagaacc ttatccatga
    32341 tctgctacct cgaattctgc ctccacgcca aaacgaagct cctcctcaga gagcacctga
    32401 attctcaagc ggtaggttcc aggaccgtca ggggcgaagc tgcccttcca tggcacggcc
    32461 agacggacag attcctccga aagctccgtc agatagccgc agaaacccgc caggctttcc
    32521 acctgttccc agctctcctt tccatccttc tctgtctttt tctcaatggc cggagagaga
    32581 atgtactgaa tgcttctgcc tgtatcattg tggagaataa aagacagctc tgaatcctcc
    32641 gccgtcacct gcctgggatc catctccatc cagatctgtt ctccatacgc tccaaagccg
    32701 taaaccgttc caaacagtct ccaaaccgct tcactctgct ccccgtccca ggtgtagaag
    32761 gaggaacctc ctgccgcaag ctccggaata cttccctccg aatccggaaa ggacagccac
    32821 agctctttcg tctcctcgga ttccatggtg agcgtcagct ttcccggaaa atattcgttc
    32881 ataggaagct cctctttctc tgcctctgac agcagcgctc caagcttctc cagatcctcc
    32941 ctgtttccaa ggctttccgt cctttcgccg ttttcaaatg ttccggaaag ctccgctttt
    33001 acaacagccc cgttctcctc cagaaattca ggagaaaatc cctgcgcttc aggcgcagtc
    33061 tcctccctga caagttctgc gtaaagcttc ccgttctgga tagaataggt tttccaaaat
    33121 ccctcttcct gaggcggaac cagaaacgcg cctcttttct ccgcctcctc cagataggaa
    33181 attccctcca ttccctcctc cagtgcagcg gacaggctgg aaatccctga ggacgtatct
    33241 cctttttcca gaagaaggaa ctgtccatta tgaaactgac tggcgctgta gcctgctccg
    33301 ctccagtcct ttccgcaggt cagcccctcc agaggatttt cttttataag acaaatacct
    33361 aaaatatagc tgtagccgtc ctcggacttc ctgcccgaaa acaggtagct gtccttgaaa
    33421 aaagaaacgg ctttctctgt ctcctcctcc ggcagaggct caaaccttct gtctgggaac
    33481 tggctttcca ccgcctgcaa cgcgcggccc agcgcctcct ctgcctctgg atgtttcgtc
    33541 tgttcctgct gctctggaac cggattatga actggctccc catcctgcgc cccctgacat
    33601 cctgtcagaa gacacgcggc agcggcagcc agaaaaatcc ccttccatct atatctcatt
    33661 agctaaaatc ctttctttcc cgtttatttt ctccacacat atgtcgggaa ccctgcgccc
    33721 tgcagcagaa tctctgcgcc gtttaggctc ccggtccggc cgggccgctg ttttctccct
    33781 gggaggccgg gccagccggg ccttcaggag cggtggtctc aggctgagtg ggcgcaggcg
    33841 tctctgccgg ttttgtaggc tgaacctgct ccttagacgg ttctgacggc gcctcctggg
    33901 acggtttcgc cggttccgac ggcttagcgg cctctgagga tggttctgac ggcgccggag
    33961 cctgggtgga tggctctgtc tcctgcggtt tcgccggagc cgacggtttt tccgtgccct
    34021 ccaggttata gcagagtacc ggcattccgg ctgaaatatt ctcgtaaatc ttctttgcta
    34081 cgctgtgggg caggttaata cagccgtggg agccccctgt cttgtagatc gttcctccaa
    34141 actctgaacg ccaggtggcg tcgtgcattc cgatccctcc gttaaacggc atccagtaat
    34201 ccactggcgt acggtaattt tcccctttca gcacagcgtc tctctgttta tacgtcagag
    34261 ggaaggaacc ggccggagtt ccccagccct ttgacaggtt tccggataca aaatccgact
    34321 ccactaacag agcgccgtcc ttatagaaga acaggtgctg ggcagtgagg ttaatctcca
    34381 cgtacgtatc gccatagtcg tttgcgccgt ggctggccgc cttctgggag tataccggct
    34441 ctctgccgct ctggctttcc ccggaacgga tcagcgccgc cagctcgtcc gcctcctcag
    34501 cctggttgat cttccagcca taggagccgc ccttaatggt aactgtcttt ccataagagg
    34561 tctttaatgt cttagacttg tgatttgtat tgtatttatc cgccagctcc tttacatagg
    34621 cggaaacctt tccggagtcc acgcctgcgc tgccgtcggc attgggaacc agccactcat
    34681 ggatcctgtc gcctgacaga gtttctgtct ggtctccgaa tttgtaggtg atcgtcacgc
    34741 ctgctgcctt gttcatattt tcacagagcg tcttcagagt ctcgtcgtcc gccgtcacct
    34801 caggctcctg gtaggccccc agctcctcca gagaaatgtt tgtctccagc tttaagattg
    34861 cctcggaaac ttccttctcc acaagctcat agtctgccag cgttccctcc ttctccggta
    34921 caatcgtgta tccgttttcc tttgaatagt ctgacaggcg ggcgttctcc ggctcctttg
    34981 ccgtctcctc gtcaaagcag gccagcccct ttaaagccgt ctcaaacgct tcctcatcat
    35041 actccatcat ggtctgaatc tggtagctgt ccgggctgaa cacccgaagt ccccaggcaa
    35101 acggattctg ggacgcgata atcttctcca ggctgccgtc aaatttcgcc tggagcccaa
    35161 tgtctttctg ggagatctgc tctgtcttct cccctctctc ctcaatggta aggacgtagc
    35221 cgttaattcc cccagcgatc atctcctgag cctcggcggc tgtctttcct gccacgtcca
    35281 gcccgttaat ctccgttccc gggaagaaaa cgcggctgta acggctgctc atgcctgcat
    35341 aggaaattcc tccgatcaca agaactgccg cagcagctcc cgccgcaatg gctgtctgct
    35401 ttctgcccca gtgaaagcct cctccgtctc ccggatcctt gggctgcctg gaaacaggct
    35461 ttcttctttc cgccatgcct gacggttcag ctgttccctt ccgcctgctt ctgcctctgg
    35521 ctcggcttct gccctggcct tctctatctg aactactgtt ttctgacggc cgccctgtct
    35581 gcgggctgcc cttcagattt tcattcttct ccagtccatc aatcattcca aattaacttc
    35641 ctttctttcc cttgcaccgt tttactgaag cgcccctttc tcctggcgct gtcccggcca
    35701 ttgtataatt ctagctgact ttatatagta agtcaatgtc cgaaatctta cagttcttac
    35761 gtttttctta atcccttttc tgctgtactg gcagtcgaag cgcttcttcc ttcctgtcat
    35821 ccgcccccgc ctgatcgata aaaagcagct tctgcatact ttcttctgca aaaactgctt
    35881 ttcctctgtc ttccggtacc tgcgcggaat ctgccgactt tacagtctgc ctccaaacag
    35941 gccttttttc ttatgttttt cgtttccctc cggtgcaact ccgttcatag cgtcgtcgaa
    36001 gcggcgaagc gcctctttct gctcctcggt aagcttctcc ggaacctgga caaccagagt
    36061 tacgaagtga tcgcctctga cgttcttatt tctgagagag gggactccct ttccttttaa
    36121 gcggactctc gtatcggtct gggttcccgg ttttacctcg tactctactt cgccgtccac
    36181 cgtcttaata cggatggctc cgcccagggc tgccttggca aaagaaatgg gaaccgtaga
    36241 gtaaatgctg gtatcctgac gcttaaagac aggatggttg gatacgatta cctctaccag
    36301 cagatcgcct ctctcgccgc cgtttacgcc cggctctccg tttccgcggt ctcttaacat
    36361 ctgtccattg tcaataccgg ccggaatcgt gaccttgatt ttctttcttc ttgtcacata
    36421 gccggttcca tagcagtccg gacatttttc cttgataatc tttcctgttc cccgacagtc
    36481 cggacaggtc tgtacgttct gtacctggcc gaagaaggac tgctgggtat acatgatttt
    36541 accttttcca ttacacttgg aacaggtctg aggctgtgtt cctggctttg cgcctgttcc
    36601 gtggcacttc tcacaggtct cctttaaatc cagctcaatc tctttctcac agccgaaaat
    36661 tgcttcctca aatgtaatgc ggatgctggt tctcacattg gctcccttca tagggccatt
    36721 gcttcttccc ctgcttcttc cgcctccgaa aatatctccg aaaaagtctc cgaaaatatc
    36781 tcccatatct gcgcctgaga aatcaaaacc tccaaagcct ccggctcccg ctcctgcgcc
    36841 tccgtcgaaa gcggcatggc caaactggtc gtactgctgg cgcttctgcg gatcgcttaa
    36901 tacactgtag gcctcggatg cttccttaaa cttcttctcc gcctccttgt cccccggatt
    36961 ggcatcggga tggtactttt tggcaagggt tctgtatgct tttttgaggg cggcgtcatc
    37021 tgcatccttg gaaacgccta agacctcgta ataatctctc ttactttctg ccatgtcagc
    37081 tcttcctctc taaaccccgc aaaggggatt gggcgttccc gccccatccc catcacggtt
    37141 tctattcgtt ttcctgccgg aagattatac ttccttaaag tctccgtcca ctacattgtc
    37201 atctgctccc tgggaagctc ccatgtcagg tgccggacct gcctggcctg ctgcacctgc
    37261 tgcctgagcc tgctcgtaaa ccttagcaaa cagtgcctgt gcgctggcca ttaatttctc
    37321 cttgccagcc ttgatatctt ctacctgcgc gtctgtcatc tggtcaatcg gagcgcggtt
    37381 gattgcttcc ttcagtgcat ttaagtctgc ctctacggct gccttatcgt tggcgtcgat
    37441 cttgtcgccg acctcctcta aggccttctc tgtctggaat accatggaat ctgcgtcgtt
    37501 tctcgcgtca atggcttcct ttctcttctt atcctgagcc tcgtactcag ctgcctcctt
    37561 aacggccttc tcaatatcgg aatcagacat attggagccg gaggtaatgg taatgtgctg
    37621 ctcttttcct gttcccagat ccttagcaga tacatttaca ataccgtttg catcgatatc
    37681 gaaagtaacc tcaatctgcg gaacgcctct tcttgccggc ggaattccgt ccagacggaa
    37741 ctgtcccaga gtcttgttgt ctcttgcgaa ctgtctctcg ccctgtacga catgaatatc
    37801 tacggcagtc tggttatctg ctgctgtgga gaaaatctgg ctcttcttag tcggaatagt
    37861 cgtatttctc tcaatcagct tcgtagcgat tccgcccatg gtctcgatgg acagggaaag
    37921 aggtgttacg tccagaagaa ggatgtctcc tgcgcctgca tcacctgcca gcttaccgcc
    37981 ctggatagct gctcctaaag caacgcactc gtctgggttt aaagtcttgc tcggctcctg
    38041 gcctgtcagc tgttttacct tctcctgagc agccagcata cgtgtggaac cgccgactaa
    38101 cagaaccttg cttaactcag aagctgtaag gcctgcgtcc tttaacgcgt tctgaaccgg
    38161 aattgccgtt ctctcgatta aatcgtgtgt cagctcgtca aatttagctc tggacaggtt
    38221 catatccagg tgcttcggtc cctcgctggt agctgtgatg aatggaaggt taatgtttgt
    38281 agtagtagct gtggaaagct ctttctttgc cttctcagct gcctctttta atctctgaag
    38341 agccatctta tcagcggaga ggtctacgcc ctctgccttc ttgaattcat caatcatcca
    38401 ctgtgtaatg cggttgtcga aatcatctcc gcctaaccgt gtatcgccgt ttgtagaaag
    38461 aacctcgatg acgccgtcgc cgatttcaat gatggaaaca tcgaatgtac cgccgcccag
    38521 gtcgtatacc ataatcttct gctctttctc attgtcaagg ccgtatgcca gagctgctgc
    38581 tgtcggctca ttgataatac gctttacatc aagacctgca atctttcctg catccttggt
    38641 tgcctgacgc tgtgcgtcat taaagtaagc cggaactgta ataacagcct ctgttacctt
    38701 ctcgcccaga taggcctctg catctgcctt cagtttctga aggatcatag cggagatctc
    38761 ctgcggagag tacttcttgt catcgatgga taccttatag tctgtaccca tatgtctctt
    38821 aatggaagtg atagtctttt ctgcgtttgt aactgcctgg cgctttgccg gctctcccac
    38881 taatctctct cctgtctttg tgaatgccac tacggatggt gttgttctga caccctctgt
    38941 atttgcgatt acaaccggct ttccgccctc cataactgcc acgcagctat tagttgtacc
    39001 taagtcaata ccaataattt tgctcatagc tttttcctcc tgattcactc tatgtgtcaa
    39061 tcaaaatgtt gctgtctaac ttttagttgg ctacctttac catgctgtgc cttactacgc
    39121 tgtctctgta aaggtatcct ttctggaatt cttcggctat cacattctct ccgaagttct
    39181 cgtcctcaat gtgcatcacc gcgttgtgga aattggggtc aaacggctgt cctactgcct
    39241 caatcggctt aacgcccaga tcctctaatg tctttaacag ctgcttgtat atcatgttca
    39301 tgccctcagc gaatgcgtcg ccgccttcag gcacggcctt taagcctctc tcgaaattgt
    39361 caatgaccgg aaggattttc tcaatcacat ccttggctcc aatctcgtac atagcagatt
    39421 tttctttctc tgttctcttt cggaagttgt caaactcagc catatttctc ttcagctggt
    39481 ccgtcagctc ttcaatctgc tgatcccgct tatccttctt ctttgagaaa aatccctttt
    39541 tctctggctg ggaagcgtcc ggggctgcct cgttctctcc ggctctcccg tctccctctt
    39601 ccttctgctc ctcgccgcag ttttgggcag cgctgtctgt acaggttccg gcttcgtttt
    39661 ccatctcagc ctctgtacac tctctgtctt tcatctcttc gctcacttga cttcaccttt
    39721 ccttactccg tccggcgggt tctattcttt atgaaaggta gcttccagct ggttcatcag
    39781 agaacgcagg gtatttacca ccttctcgta atccatcctc ttaggaccaa taattcctat
    39841 ggttccacga agtccgtcac tcagcacgta attggctgtt acaacgctgc agtccttcat
    39901 ggactggact ggcgtctcgt ctccgatgta aacctgaatc cccgtgcttt cctgctcctg
    39961 aggcgtatcg gaaagcagat ttcttaaaag ctccttctgc tccagggttc ctaaaagctc
    40021 gctggcctta tggccgtcgc ttaactccgg atatttgaaa atattcgtcg ctccgctggt
    40081 ataaatctgt aaatcctctt cgttagcctt aatggcctcc gctacctcgt ttaacaccag
    40141 atccacaatc tgtcttctgc ttcctgcctg ttccttcatc tttgtgatga cgcccaggtt
    40201 aatctgatcc actgtcagtc cgtttaaagc attgttcagg agaatattca gattcagaag
    40261 ttcctcctca ctcagctctc cgtccagagc caccatggaa ttcttaatga tgtttccttc
    40321 cagtacggta acaatcagaa gcttccctgc ttccattctc gaaagctgga taaacttgat
    40381 tttagtctga tggtagtggg gaccgcttat catggtggca taattggtat tcgccgccaa
    40441 gacactggcc atctgcttta agagcagctc cacccggtct accttctgta tcatcagttc
    40501 cttgatctct gtgacctcgt cttctttctc cctaatgata tgatccacat aaaacctgta
    40561 tcctttatca gaaggaatcc ttccagcaga ggtatgcggc tggataatgt accccagctc
    40621 ttccagatct gacatttcgt tccggatagt ggctgaactc aggttcaggt ctgaatactt
    40681 tgaaatggtt ctggaaccaa ccggttcccc cgtttccaag taggtctgaa taatagcctt
    40741 taaaattctt tctttccttt cacccagctc caagcgcctc acatcctttc ctgt
//
LOCUS       DBMDUW010000021        40624 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_837_length_40624_cov_4.421070, whole genome shotgun sequence.
ACCESSION   DBMDUW010000021 DBMDUW010000000
VERSION     DBMDUW010000021.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 40624)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 40624)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40624
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_837_length_40624_cov_4.421070"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            6..131
                     /locus_tag="ACZPCR_05830"
     CDS             6..131
                     /locus_tag="ACZPCR_05830"
                     /inference="COORDINATES: protein motif:HMM:NF042595.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6756 family protein"
                     /protein_id="HIR1230430.1"
                     /translation="MYGLNDFYIVSKKFEWLISECHEDVVSFVGDSLDLSCFDEQ"
     gene            163..693
                     /locus_tag="ACZPCR_05835"
     CDS             163..693
                     /locus_tag="ACZPCR_05835"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016298067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1230431.1"
                     /translation="MMKYRTLHAEEICRELFKDFIRHQIVEKCWRRENGTWEIKDAPF
                     VDDWTEQDYQVLISCLKHTVLSGGFVYAAFYDGKLKGFVSVESELSDDEHRYCDLSSI
                     HVSEDMRNRGIGKSLFLAAKEWARKKGARKLYISAHSAVESQAFYQSMGCTEAEVYNQ
                     KHVEAEPYDCQLECAL"
     gene            771..1538
                     /locus_tag="ACZPCR_05840"
     CDS             771..1538
                     /locus_tag="ACZPCR_05840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016441391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HIR1230432.1"
                     /translation="MGMIKNEIPILEFDTEQTAVISPVHENLNLKLPKKCVFAFLGDY
                     IEEYADKSDTRQVSSFISATKRYPIYVTQYKGEEIVLCQAPVGAAAAVQILDWLIGYG
                     VCEIISAGSCGALEYFDEGTFLVPSKALRDEGTSYHYAPPSRFMEINERAKKAIEKTI
                     VEHNMKYQEVITWSTDGFFRETREKVEYRRSEGCSVVEMECSALAACAAFRKAIWGML
                     LYTADSLADIAQYDERHWGGNAYEYALILCLDAVLAI"
     gene            complement(1658..2479)
                     /locus_tag="ACZPCR_05845"
     CDS             complement(1658..2479)
                     /locus_tag="ACZPCR_05845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003525020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HIR1230433.1"
                     /translation="MDLNLDECLEPFTAYLKQKGKSPNTIRSYLCAIRLYASLYSRLN
                     PANLRAYRAHLLDHYRINTVNARIYAVNCFLDSLRFSFRLEPVRQQQCTYLDCVISQR
                     DYEKLKRRLRQDHNFYWYFVVRFLGATGARISELLQIKVENLKSGRLDLYTKGGKMRR
                     LYLPRRLCDEALAWFGEKGVTSGFIFLNHRGQVITSRGVAIQLKHLAVRYHIDPDTVY
                     PHSFRHRFAKNFLKKYNDIALLADLMGHDSIETTRIYLTRSSAEQKELLDRIITW"
     gene            complement(2486..3307)
                     /locus_tag="ACZPCR_05850"
     CDS             complement(2486..3307)
                     /locus_tag="ACZPCR_05850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HIR1230434.1"
                     /translation="MNAVNLQISEFRQYLISKDMAANTVQVYSYALRQFLCRYHQADF
                     SSLHLYKVFLLEHYKPQTVNLRLRALNAYLEFTREKSKKLPLVRIQQKNYLENVISEA
                     DYEYLKSCLLRDKRYLYYFLIRFMAATGARVSEVVQFQAEDVQKGFKEIYSKGNKARR
                     IYIPKALRTDALLWLQAAGIRKGDIFLNRFGRRITPAGIRGQLKTLAVLYGINPDVVH
                     PHSFRHRFAKSFIEKCGDISLLSDLLGHKTIETTRIYLRRSSNEQYEIVNKVVDW"
     gene            3651..5261
                     /locus_tag="ACZPCR_05855"
     CDS             3651..5261
                     /locus_tag="ACZPCR_05855"
                     /inference="COORDINATES: protein motif:HMM:NF016800.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008754 - O-antigen ligase activity
                     [Evidence IEA];
                     GO_function: GO:0008755 - O antigen polymerase activity
                     [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HIR1230435.1"
                     /translation="MSSHLIRPAAEEKRPWRYMELAASVYTLALLCIFPFVVHNKYFD
                     ILPTKYQAYAVLTCAALIFTVIYLIASGAAVRGIQSLRDGTWKGHLSFVDWSVLAFEA
                     LLIFSTLQSEFPYESFWGNEGRYTGLFTMSLYVFSYFFISRFLRWKQWYLDAFLGGGI
                     LACLWGITDYFRMDIFHFKERIAASPDTFTSSFGNINTYTIYVAMVIAVAAALFVTSK
                     SVGRSFYYYICFVIGMFAIIMGVSDNAYLSLGALFALLPLYTFTKGQAVRRYVVLTAT
                     VFTVVRCIAWINTAYADTVIGIDSLFSFLAGHDKLMVLACGSWAFAAALYLLKFAVKR
                     EPKAVLLGLRVAWGVLLAAVFAAAFWIFYDANFAGHQDKYQAIAKYIVFNDNWGTNRG
                     FAWRISWENFKSFPLIHKIFGFGPDTFGIITTFNNYKEMSEIYHVTFDNAHNEYLHFL
                     LTIGAAGFAAYLSFLVSAFVKMTRRAADNPLILAPLLAFTCYSVQAAVNLNVPITAPF
                     MWAFLAMGLALVRRDDKQKKSEDAGAEK"
     gene            5282..7135
                     /locus_tag="ACZPCR_05860"
     CDS             5282..7135
                     /locus_tag="ACZPCR_05860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HIR1230436.1"
                     /translation="MFEKYMPKNKRARMLILMAADIAAIQLCSFLALLIRFDLNIAKI
                     PAEYSANVLSYGLIHTALTIAFFFLAHLYSTMWSVAGIREVIRIVIACGFSTVTQIAG
                     MTLMQYFMPRSYYIISFFGLCITVTGIRLSYRIKNSLFPSGNRGGDRIMIVGAGTSGS
                     VILKEMMTSRHTNGTVVCFVDDDLNKKGKYLNGVPIAGSREDIPGLAREYRVDEIYVA
                     LPSAPAKERKKIIEICRETDCRIKVLPGIYQLLNGEVSVAKLREVQIEDLLGRDPIRV
                     NLDEIMGYVQDKVILVTGGGGSIGSELCRQIAGHKPRQLIVFDVYENNAYDLQQELER
                     TFPDLNLTVLIGSVRNTHRIETVFETYRPDIVYHAAAHKHVPLMENSPNEAIKNNVFG
                     TYKTARAAGRYGAKRFVLISTDKAVNPTNIMGASKRMCEMVVQMMDRRYKTEFVAVRF
                     GNVLGSNGSVIPLFRKQIAEGGPVTVTHPDIIRYFMTIPEAVSLVLQAGAYAKGGEIF
                     VLNMGEPVRILDLAKNLIRLSGYVPNEDIMIEFTGLRPGEKLYEEMLMDEEGMQDTPN
                     KLIHIGKPIEFDEEEFQKQLDELYEIANQDSDHIKEAVQRIVPTYVIKKDS"
     gene            complement(7151..7705)
                     /locus_tag="ACZPCR_05865"
     CDS             complement(7151..7705)
                     /locus_tag="ACZPCR_05865"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012792.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1230437.1"
                     /translation="MTRLPLQFSIQAAVPEDCPALYRLMTDTAFSVQNKDWFFPDSLE
                     FIKTHIKDRGLILKACPDGPEGGAGQAARDSLAAFLLIRFPDPTEDNLGTYLSLSGQE
                     LMQVAHMETVAVAAGFTGYGLQRKLLIEGEKAAAAAGYRHFMATVHPDNHYSLSNFQR
                     LGYKKIAEALKYGGLRRWVLEKSI"
     gene            7851..8864
                     /locus_tag="ACZPCR_05870"
     CDS             7851..8864
                     /locus_tag="ACZPCR_05870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HIR1230438.1"
                     /translation="MKEIGEMRAEDGREGPAFMTVGGLCEEWLRSVKPMVKPSTYACY
                     LTMVEKHIRGELGKVQAADLTNQMIMDFIHSRQKQGLSAGTVRLLLFLLKSIVQAGEE
                     MGACPGEALYLKLPRQAGKRKEIMEWEDFHKMVSYLLNSRKSFELGLLISLGTGIRVG
                     ELCGMRWEDIDLDTGVLKVRRTVSRIRNVEEAQAAVPGGKTILQIGTPKTGSSVRDIP
                     LPGFLTERLRERFCERRFSPQTYVLTGSGRVMEPRSVQRRFKNLLRRCGIKPVSVHSL
                     RHSFASKWIEQGLDSKALSEILGHSSVKITMDIYVHSTMNQKKNYMDHVLEGIVIDQR
                     SSL"
     gene            8906..10357
                     /locus_tag="ACZPCR_05875"
     CDS             8906..10357
                     /locus_tag="ACZPCR_05875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chain-length determining protein"
                     /protein_id="HIR1230439.1"
                     /translation="MESQYNYEQEIDLKDLMFAVLRKWRPIILIAIVFAVLLGGMKGA
                     GALKQMKDSEYLAAKQQEYDNSMDQYAISKASLEKEVENIKASLESQNEYMEKSVLMN
                     INPYDEYVTAAAFYVGTDYQIMPGMAYQNPNTASSIMQAYMSMIQNGDMYNYVLNGMS
                     APLDRRYLQELVTVTPNLENNMFDIRVISSSEEGASSIMKLIMDSLNEYSQVITQAIG
                     PHTLKVMSSSARPGADMAQTPEMIGAGGSPDVYTTVDLELEKKQQEQSARIAELNQSL
                     TDKTKELADLKEPSISLPRKGGAVKSAVKYAVLGGVLGGFLSVFFICVAFLMSDKLGS
                     DKELRRRYGLMILGLFDDAGRKGLFSFVDRFLDRMEGTAGRKMDKETVCSVVAANVMN
                     YAGDAKQLLLVTSAPDLDLEAVRSDIAPALTDLFVTAGGNLDSQADAIRKAASCEAVI
                     LVEKRKSSSFSGIERELDIVRSLDKKVLGCIVL"
     gene            10501..10668
                     /locus_tag="ACZPCR_05880"
     CDS             10501..10668
                     /locus_tag="ACZPCR_05880"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230440.1"
                     /translation="MDAAAQLEELMIEVEHLKDENEILFDTVVQMKSSLDRLITVYIG
                     SGKQKMRQAGM"
     gene            complement(10919..11317)
                     /locus_tag="ACZPCR_05885"
     CDS             complement(10919..11317)
                     /locus_tag="ACZPCR_05885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichuronopeptide"
                     /protein_id="HIR1230441.1"
                     /translation="MKELTVFYCPHCGYYGYYLIPRRAVCPSCRIHMTKLPMSCQQFM
                     DLDYRMRDQLIGSQILDGAEPHSSVVQRITEQARRFNSRAEIAKQAETIQELKQEIET
                     LKAENRKLSDTVAWMHDTIWKLTRGEGEER"
     gene            complement(11604..12935)
                     /locus_tag="ACZPCR_05890"
     CDS             complement(11604..12935)
                     /locus_tag="ACZPCR_05890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HIR1230442.1"
                     /translation="MRKTTKLIAVLSAAAMMSMAAPNVLNDSFLLNVYAANGWVQEDS
                     EWHFYDEDGYLESNTWKKRGSDWYYLDDDGNVTVNQRVDEYYVDSEGKMVKNKWVSPE
                     GEETYDSPDSASDQEWNYFDKNGKIVTSRWMAIQNNWHYFDEDGIMQTGVLELDGSVY
                     YLGKESDGVRKTGWILLEDITEDTDDEGIWCYFDEDGKLVVNQIDRKIDGAFYTFENG
                     QMQTGWVKTEKTAEGEADSPASYQYYDEEQGGKRASGWYQIEGIEGISEEGEEYYFYF
                     KNGKPYYSQEAGLELFNINSERYAFNEKGEMQTGVQTLAVKGGGEAVYYFGDDGAMKT
                     GKQTIYDEDAEENQTWYFYPSGSKKGQGYTGERDNRVYVNGLMKKADPELRYEPVAAG
                     DRTYLVNTSGTIQKASSSSTSDAKPELLKGFKDYKDSNDTVWTVDTNGIIQ"
     gene            complement(13080..14711)
                     /locus_tag="ACZPCR_05895"
     CDS             complement(13080..14711)
                     /locus_tag="ACZPCR_05895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016283056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase catalytic domain-containing protein"
                     /protein_id="HIR1230443.1"
                     /translation="MKQVKLLDCTLRDGGYVNDWNFGHDNMVNIFERLISSGVDILEV
                     GFLDDRRPFDRNRTIMPDTASADRLFGSLDKKNTMLVGMIDYGTCAIENLAPCSESCL
                     DGIRVIFKKHIMKEALAFCTQVKALGYQVFVQAVSITSYSDRELLDLIDLVNALNPYA
                     LSMVDTYGLLHQSSLLHYFEILDHNLNPEIAIGYHSHNNFQMAYANSMEMLSKPVNRT
                     VLVDASLYGMGKSAGNLPVELISMHMNLHYGKSYDTSQMLEAIDINIIPFFEKSPWGY
                     SLFFYIAASNNCHPNYVKFLMDKHTLSLKSLNVILGQIEPEKKLMYDKDYIENLYLNY
                     QNMECSDEDDLKRLSREWSGKPLLLLGPGKNMELQRDRIDRYIKEHAPVVIAVNYIPE
                     NIPVDYAFLSNSRRYVQLTTRLLELKKEQEHAQASPVRVIATSNVTNVNGSFDYTLNY
                     NSLIDRDAEIIDNSFVMLLNVLVKAGVSQAACAGFDGYSVGGDNYFNSDMDYRIGKEK
                     SMNLNSYVKNVLKKLSGSFQAEFITDSWYEEKQSH"
     gene            complement(14716..15384)
                     /locus_tag="ACZPCR_05900"
     CDS             complement(14716..15384)
                     /locus_tag="ACZPCR_05900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HIR1230444.1"
                     /translation="MYKGIIFDLDGTLLDTSEGVLASIRHTIKTMNYRELPLETLLTF
                     IGPPVKRSLMKHYGLTDQEADEATEVFRQQYKNKDLLKAKPYDGILELLKALKDQGFL
                     VGVATLKREDYAHTILEHFGIAKLCDLICGSDFESRMTKTDVLRKCLSGLSLEPSEAL
                     LIGDTSSDGNGAKEAGTDFMAVTFGFGYKTKEAWEKHFSPVFTAADTGEIADFLQVSL
                     VKGR"
     gene            complement(15357..16148)
                     /locus_tag="ACZPCR_05905"
     CDS             complement(15357..16148)
                     /locus_tag="ACZPCR_05905"
                     /EC_number="2.7.7.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008397543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008690 - 3-deoxy-manno-octulosonate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0033468 -
                     CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="HIR1230445.1"
                     /translation="MNMKITGIIPARYGSTRFPGKPLALLDGRPMLLHVFEHASESRL
                     LTGIFAATESPNIKEACESLSIPCLMTDPSHENPTSRLREAAASIPSDLYVMIGGDEP
                     LLTGEDIDLVVQAALDRMEREDALFVVNAMAPVLSPSEAMDTANIKVVCGEDGRGLYT
                     SRIPIPYPKGELNFTYQKFASIGVYTRKALDFFTDTPKGPLETIEECDLLRFLEHNVP
                     VYFVNTGHPSLSVDTKKDLRQVRLMAEQLNTINGGLSCTKELSSI"
     gene            16393..18318
                     /locus_tag="ACZPCR_05910"
     CDS             16393..18318
                     /locus_tag="ACZPCR_05910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005948 - acetolactate synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009099 - L-valine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-binding protein"
                     /protein_id="HIR1230446.1"
                     /translation="MRIKVSNYIAQKLLEAGIKDVFMITGGGAMHLDDALGHQEGLNC
                     IYNHHEQACAMAAEAYARIHGQIAAVCVTTGPGGINAMTGVAGGFMDSIPMFIVSGQV
                     RYDTMSRSTDLHLRAMGDQEFDITASVANMTKYTEMITDPMRIRFCMEKALYLAYAGR
                     PGPVWLDVPLNVQAAMVETEDLTGFDPADYEAGGTGWAKKSEAEIPMDTAGQGEYRAL
                     LPKKVEKETAREIIKKIRAARRPVINAGNGIRIAGAHEVFIRVAEALQIPVVTGADSI
                     DCIWDEHPLYTGKGGNVGDRAGNFAIQNSDLLLSLGSRLSFRQVGYRFDTWAREAYTI
                     INDIDAEELKKPTLHVDMPVHADVKDLLETMEEVLKEEELSRDAMDGETREAQEQWLA
                     QCRTWKEKYPVVLPRHMEGGTETEANVYAFAHELSARLLEDQIVVVGNGSANVVCGHA
                     NIMKKGQRFISNSGIASMGYGLPASIGACIAGSDHDIILVTGDGSIQMNLQELQTVIG
                     RWLPIKIFVINNGGYHSIRQTQKNFFGEPLIGIGVDSRDLTFPSMEKLAWAYGFPYVS
                     IHGNKELDEKLEEALAIDGPVICEVFVTLDQNFEPKSAAKKLPDGTMVSPPLEDLAPF
                     LSDEEMDENMIIPRIQK"
     gene            18341..19282
                     /locus_tag="ACZPCR_05915"
     CDS             18341..19282
                     /locus_tag="ACZPCR_05915"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HIR1230447.1"
                     /translation="MKIVATGATSFVGSGAVKALLERGHKVYAVLRKGSSKADRLLIN
                     GAMPENLVILEEDLGSLERLAEQIPEPCDVFLHMGWKGAGSDSRSAAAIQEENAKDSL
                     NAVQAAKALGCRRFVFTGSQAEYGVHDALMNEETGCRPTSPYGEAKLKVRIEAEALCR
                     KLSMDYGHARIFSTYGIGDHPWSLLSTCVNTFLSGGVMEMGACTQDWNFMYIDDAGRA
                     VAMLCEYQKSLMEQGCVYNLGGPMDETGPLKHFVETVYEMCGRKGSCVYGVRKPNAEG
                     VVNLIPDLTKMKRVIGWEPRVRFRDGMARVIESVRPS"
     gene            19402..20415
                     /locus_tag="ACZPCR_05920"
     CDS             19402..20415
                     /locus_tag="ACZPCR_05920"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006776547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1230448.1"
                     /translation="MKKISILIPCYNEEENVGPISQAVVETMTRELPEYDYELVFIDN
                     DSTDQTRPILRELCRQNPRIKAIFNAKNFGQFNSPYYGLLQVTGDCVISMVADFQDPV
                     ELIPQYVREWEKGYKIVIGIKTGSKENPVMYWLRSCYYKMIKKLSDVEQIEHFTGSGL
                     YDREFIEVLRRLDDPTPFLRGIVAELGYKRKEIPYVQPQRRAGKTHNNFYRLYDAAML
                     SITSYTKVGLRLATIFGSICAGISIAVAFVYLILKLLHWNDFPAGMAPVLIGMCFLGS
                     VQIFFIGLVGEYILSINARVMKRPLVVEEERLNFDSPDAQETERENEETEKALKQEKK
                     HEI"
     gene            20405..22591
                     /locus_tag="ACZPCR_05925"
     CDS             20405..22591
                     /locus_tag="ACZPCR_05925"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009101 - glycoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1230449.1"
                     /translation="MKFNVDVVRIRENSIQLNGWAIGKTPEAAISYDVEDENHKHLEH
                     KYVATRRDDVSQIYFGSVIDREFGFDIQFPYERGKDYYLVIRGEGRRIRVKYNEDLIA
                     KRSSVAHKKMQKIRDLMNMETVRVAYDFWKENGLKALIKKSKHKIQGIDNDYDYAEWY
                     DLTKPTEEELAAQRTAVFEYMPKLSVVIPAYKTPERYLKEMLNSILAQTYENWEICIA
                     DGSPAGESCERVLKRYAEQDRRFKYVILGENKGISGNTNAAMDMAAGDFIVLADHDDT
                     LPPHALYEVVKAINEHPEADVIYSDEDKMDMDGGALFDPHFKPDFNIDLLRSVNYICH
                     LFVVSHDLAARTGGFRQEFDGAQDYDFIFRCVESAGQVYHIPKVLYHWRCHQNSTASN
                     PESKLYAFEAGSRAIMAHYDRVGIQAERVEKGVDYGIYHSIYRIQGEPLVSVIIPNKD
                     HRQDLDLCIRSIMEKASYRNLEFVVVENNSQDPETFAYYEKLQKEFPNVRVVKWEREF
                     NYSAINNFGVTFAKGEYLLFLNNDTEPIEPRFIEEMLGLCQRDDVGVVGARLLYQDDT
                     IQHAGVVVGFGGIAGHTFIGLHKAENSYFHRAMSTQDYSAVTAACMMSKKSLFEEVGG
                     FTEELAVAFNDIDYCMKVRAAGKLVVYNPYALLYHYESKSRGLEDTPEKIARFNREIR
                     IFSERWPKILEEGDPYYNPNLTLRKSNFALRDLKKEAIGEPYKLEI"
     gene            22632..23627
                     /locus_tag="ACZPCR_05930"
     CDS             22632..23627
                     /locus_tag="ACZPCR_05930"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1230450.1"
                     /translation="MTATVTVIIPNYNGMKFLEPCFEALKAQTYRNFKILVVDNGSSD
                     GSKEWLKAQGVDTIFLEENTGFSGAVNIGIKAADTPYVILLNNDTKADEYYVAEMVKA
                     IERSPKIFSVSSRMIQMYHPDLMDDAGDMYCILGWAYQRGIGQSVKKYGRSRRVFSAC
                     AGAAIYRREVFEQIGYFDEMHFAYLEDLDVGYRARIYGYDNVYCPAAVVYHVGSGTSG
                     SKYNAFKVKLAARNSVYLNYKNMPLPQLVLNAAPLALGMAVKRGFFKKIGFEKEYMEG
                     LKEGFSTVKRCRKVPFCREHLKNYLQIEMELIAGLFIYTWEFASRKLSGRNTRES"
     gene            23665..25821
                     /locus_tag="ACZPCR_05935"
     CDS             23665..25821
                     /locus_tag="ACZPCR_05935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family glycopolymer transferase"
                     /protein_id="HIR1230451.1"
                     /translation="MMNQMNYDGDDELERMRQRRQMRRESRQDPDRFGYEDSRYGEGS
                     YERGSRARREAETSRSGRQSAGRAGERPERRMREGERDRARQDGGRTSQNRQSRTRDR
                     EREASGSPSFRSGYSGPKNSHKGSQRRNQRGGRGGGFQMDRRKKIFLIVGGVILALIL
                     FIAAAYAYVNHKLFGNMASVDFDEKKVENLDLSEEQLAQMKGHWMIACFGVDSREKGG
                     EMNVGKGANADVNMICSVDLESGEIKLVSVFRDTYLNISDKNTYNKINAAYAIGGPEQ
                     AVAALNKNLDLNITQYATFNWKAVADAINILGGVDIELSENERSWINAYITETVKETG
                     IGSHQIQKAGLVHMDGVQAVAYGRIRYGDTDYARTERQRIVLQAAFDKVKTADWATVN
                     NVIQTVMPQLATNINMADLIPLARQLANFHIGDTKGFPMARGEANVGKNGDCVIPQTL
                     VSNVSELHQFLFGTENYQPSSKVQSYSAHISEATGMYKEGKSIDHVPVDQGLNASSYV
                     KAKQKRAAEKAAAEQRAKEEAEAAAKKDETKEADQAETQEETKDYFGNWDEEEWDEED
                     WEDFWDGEDWYEDWGDDGIPSDGGATGPGADTSGPAGGSGDQGNSNSGENGSSKPGSG
                     SKAPEKESSPSGNGSSSGKTPGSGESKPASGENTKESVSSPEANSPVSQPSAPSSPQS
                     GSGEQGKNKEPQAPNTSNTNQEAAGPGDAGPAGPAA"
     gene            25867..27285
                     /locus_tag="ACZPCR_05940"
     CDS             25867..27285
                     /locus_tag="ACZPCR_05940"
                     /EC_number="2.7.8.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate glucose
                     phosphotransferase"
                     /protein_id="HIR1230452.1"
                     /translation="MIKDNQKRLNRFHVVLDAFVILASYWLAWFVIMVLSPKATVHNR
                     QAMAEVYILAAVMIVPLYLILYAFFHLYTPKRVQGRRTELGNIIKANTIGILAIALVL
                     FLNAKNDYVINFSRWMVVCFYVFNIVLEFLERNLIRRTLRSMRSKGYNQKHILLVGYS
                     RAAEGFIDRVSMNPEWGYQVRGILDDHEEWGKEYKGVRVIGKTGELEAILELNTLDEI
                     AITLGLREYGKLEKIVAACEKSGVHTKFIPDYNNMIPTLPYMEDLQGLPVIHIRHVPL
                     TSLTNATMKRIIDIFGALVAIVLFSPIMLGTAAAVKLTSRGPVIFSQERVGLHNKPFK
                     MYKFRSMEVQAPSQEKSKWTTPGDPRVTPVGKFIRKTSIDEMPQFFNVLKGDMSLVGP
                     RPERPFFVEKFKEEIPRYMVKHQVRPGLTGWAQVNGYRGDTSIVKRIEHDLYYIENWT
                     LGFDFKILFLTIFKGFINKNAY"
     gene            27300..29207
                     /locus_tag="ACZPCR_05945"
     CDS             27300..29207
                     /locus_tag="ACZPCR_05945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HIR1230453.1"
                     /translation="MRYEDEIDRSRRRQSRGRETVKRSGNRNPAPNRQKELTLITDSF
                     KEDARRRNGRTEGAYGGPQKSSSRKKTSKKEEKNRKAAAQGHNQSYRASAKKKAKKKR
                     RRIALIALWIVLLLGTAVFAGYKYLDIKWKGLTQRDENWNPDDLINLEISEEKQEQME
                     GYWTIAVFGLDSRNGSVGKGNNSDVNIICNLNWATGEIRMASIYRDTYLNVSDKNSYN
                     KINSAFLQGGPTQAVKALNKNLDLEIDDYAVFNWKAVAEAINILGGVDIEITKKEFYY
                     INAFITETVKATGIPSTQLKKAGMNHLDGVQAVAYGRLRLMDTDYERTARQRKVISLA
                     FEKAKKADWATLNNVIQTLLVTEQDVDTSIDLDDIVKMARGITKLHMGESYGFPEDRK
                     EGRVGSKGDCVIPNTLESNVVKLHSFLFGDENYEPSSQVKNISNKIASDCGAGGKKET
                     PKATKAPETEALSTEDLNSTEATGSHGETSPSHEYWYPWESETDDGATGPGKATRPYE
                     TGSSPYPGETHPGGESRPAGEQRPGGGTQAPQESESSPGSGPTQMPQESSSGIIIYPE
                     GGENQNGVQKPGTEQPNAPGTSGGQNGSQNTPGQIAPGGGGPENQTPGQYTDTGVILN
                     PGSVNGGQPGQ"
     gene            29283..30266
                     /locus_tag="ACZPCR_05950"
     CDS             29283..30266
                     /locus_tag="ACZPCR_05950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HIR1230454.1"
                     /translation="MIQARGKAFASVDGGNRRLAEQEKSGPGLAGREEHMGNMNIKEA
                     EEETGITRQNIRFYEKKGLIQPERNKENDYRQYSEEDIKRLKTIKMLRKLDFPVEDIK
                     EVLEGNTDFTQAVRNHLDSLKERKKELSAQINFLEKMEREGADLSNQERYLRQMEQEE
                     RQGRRFTDILEDYKRTAREESRRRFSFVPDTMARTPREFTEELLRFADQEKLNLVITR
                     EGMNPLFEIDGVSYEAFRLSGRFGIVVQCQMTEPRKQETDLAQQGEEEKQKKDSAGKK
                     AARLLHYSWPVLIWAVLFFSRAGFSWWSLLIFIGTSAALGCGCFTYWNLKN"
     gene            30394..30624
                     /locus_tag="ACZPCR_05955"
     CDS             30394..30624
                     /locus_tag="ACZPCR_05955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009253562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4318 domain-containing protein"
                     /protein_id="HIR1230455.1"
                     /translation="MLNMFKKSFWIPYEDSTVYPTMAKAMEEISRYCEERGETCVFTG
                     DDEVEIEGKRYEIYRGYENGSRGNYGIKCREK"
     gene            30817..31389
                     /gene="pth"
                     /locus_tag="ACZPCR_05960"
                     /pseudo
     CDS             30817..31389
                     /gene="pth"
                     /locus_tag="ACZPCR_05960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006771414.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - peptidyl-tRNA hydrolase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
     gene            31592..35149
                     /gene="mfd"
                     /locus_tag="ACZPCR_05965"
     CDS             31592..35149
                     /gene="mfd"
                     /locus_tag="ACZPCR_05965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HIR1230456.1"
                     /translation="MGTIFANPLEELAEFQDMNKELNEGRGPLQVSGCVDSQKAHLIS
                     ETGGGKRWKLIVTYDDSRARELFEDYRTFDPAVYLYPARDLLFYSSDIHGNLLTRQRM
                     QVFKSLLENETGTVVTTADALMDRLLPLPEIQNSCVHVACGETILLEKLKGRLSQLGY
                     ERVGQVDGMGQFSIRGGIIDIFPLTEELPVRIELWGDEVDSIRSFDLESQRSVEELQE
                     VALYPATELLLLPERMEEGLRQIEKETKAYARALREQMKTEQAARIEGSVRELSEEIK
                     EGFRVHGLGGFIQYFSETTVSFLNYFPKDHLAVFLDEPLRIKEKAEVVETEFRESMAH
                     RLEGGYLLPGQTDFLYSAKALLAMTALPCTLLLSGLDQKLSGFPVKKKYSIEAKSMGT
                     YHNGFELLIKDLERWQKGKYRVALLTASRTRASRLANDLREYGLKAYLPDQDCSQVKA
                     GEIMVTYGNLHRGFEYPLLKFAVVTEGDMFGNGQGKKRKKKKTSYQGRHIQSFSELSP
                     GDYVVHENHGLGIYRGIEKIEQDKVVKDYIKIEYADGGNLYLPATKLEGIQKYAGAEA
                     KKPKLNRLGGSEWHKTKTRVRGAVREIAKDLVKLYAARQDQEGFQYGPDTVWQREFEE
                     IFPYEETEDQLDAIDAVKRDMESRKIMDRLICGDVGYGKTEIALRAAFKAIQEGKQVV
                     YLVPTTILAQQHYNTFVQRMKDFPVRVDMMSRFRTPAEQKKTLEDLKKGLVDVLIGTH
                     RVLSKDVEFKSLGLLIIDEEQRFGVAHKEKIKQLKENVDVITLTATPIPRTLHMSLIG
                     IRDMSVLEEPPVDRLPIQTYVMEYNDEMVREAISREVARGGQVYYVYNRVNNIEEIAG
                     HVAALVPDASVTFAHGQMREHELERIMLDFVNGEIDVLVSTTIIETGLNIPNANTIII
                     HDADRLGLSQLYQIRGRVGRSNRTAYAFLMYRRDKLLREEAEKRLQAIREFTELGSGI
                     KIAMRDLEIRGAGNILGAEQHGHMEAVGYDLYCKLLNEAVLALKGETDESQEFETSVD
                     CDIDAYIPPSYIKNEYQKLDIYKRISAIESEEEYMDMQDELIDRFGELPAPVENLLLI
                     ASVKALAHSAGVTEVNINRQEARITMFRQARIDVTGIPELISRYRGDLKLRPGDAPEF
                     MYLDQRNKNKDCQRMIEKTQEILRGLKELSGRSQDAGRK"
     gene            35220..36014
                     /locus_tag="ACZPCR_05970"
     CDS             35220..36014
                     /locus_tag="ACZPCR_05970"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006861838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HIR1230457.1"
                     /translation="MENENRQGRTADVESKKQEIKSGTEGVRLNKFLSESGFCSRREA
                     DRLIEAGKVKVDGMTASMGQKVEPSQKVEADGTVISGKDRPVVLLVNKPRGIVCTTSD
                     KDRAENIVEFLNYPVRVYPVGRLDKDSEGLLLMTNQGELVNQILKGRYGHEKEYLVTV
                     NKEITASFLERMRKGVKILDTVTRPCTAEQTGEKSFRIILTQGLNRQIRRMCEALGYR
                     VKTLKRVRIMNLELGSLKTGEYREITKEEYRELKRLLEGRAGRGNL"
     gene            complement(36099..36923)
                     /locus_tag="ACZPCR_05975"
     CDS             complement(36099..36923)
                     /locus_tag="ACZPCR_05975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HIR1230458.1"
                     /translation="MKITKVTAVYYSAVGSTKAVTEKIAGLIAEKLGVPTDSYDYTLP
                     DSRTKTQNYGPSDLVVFGTSVYAGRVPNKLLPAVQNCFKADGALAVPVVTFGNRNFDN
                     GLIELRNELENNGFHTVAGAGIACRHVFSEKLAPGRPDEADWAAIEKFAVSAAEKVMN
                     LTEIPAPVSVRGDDPVGPYYTPLGTDGKPAVFLKAKPLTKAELCDSCGICVKACPMGS
                     IDAADPSLVSGICIKCQACVKKCPAGAKYFDDPAFLSHVAMLEQNYTRRAEPEFFL"
     gene            complement(37025..37585)
                     /locus_tag="ACZPCR_05980"
     CDS             complement(37025..37585)
                     /locus_tag="ACZPCR_05980"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006442040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HIR1230459.1"
                     /translation="MHFEDFEALQRTRESCRVYSDKPVSRELLTHLVEVAGLSPSACN
                     SQPWRFIVVDDPEVKGRMGEVLDDRGVCGCPWADRVPAFIVICEETAHLKPAVEAQYG
                     SQHFAQMDIGMAAMSLCCEASSLGLGTCMLGTINQEKARQLLNVPEHCPARLVIAVGY
                     PALSDAPRRKTRKSLDEIISYNQWQA"
     gene            complement(37684..38247)
                     /locus_tag="ACZPCR_05985"
     CDS             complement(37684..38247)
                     /locus_tag="ACZPCR_05985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003022180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HIR1230460.1"
                     /translation="MNTDTAASNIAVYSGRPVSEEGRLPREIQVYDFLDKLSIPYERA
                     DHPQADTIEACRDIDQALQVNMCKNLFLCNAQASAFYLLLLPGDKKFRTSVFSKQMGC
                     SRLSFADAAHMEAFLSISPGSVSVLGLMNDKEHRVKLAIDRELLEDPFLGCHPCVNTS
                     SLKIKTSDILEKFLPAVEHDFTLVDLP"
     gene            38515..40053
                     /gene="rlmD"
                     /locus_tag="ACZPCR_05990"
     CDS             38515..40053
                     /gene="rlmD"
                     /locus_tag="ACZPCR_05990"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0000154 - rRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HIR1230461.1"
                     /translation="MADRSKRTETAGKREKLVKQERKNREQPRREKGKARETGKTGEA
                     CPVYKKCGACQYLHLSYEKQLAKKREMLETLLAGSCPVKEMIRMEQPYHYRNKVHAVF
                     GHDRRGNAVSGVYKEGTHDLIPIETCLIEDEKADEIIGTIRSMLRSFKIRTFDEDTGY
                     GLLRHVLVKRGFATGEIMVVLVTASPVFPSKNNFVKALREKHPEITTIIQNINGRSTS
                     MVLGEKEHVLFGKGYIEDVLCGHRFRISSKSFYQVNPVQTEKLYNKAMELAALTGSET
                     VLDAYCGIGTIGITASGRAKRVIGVELNKDAVRDAVQNAKRNEIKNIEFYCNDAGRFM
                     SRMAAQGEKLDVVFMDPPRSGSTEEFIHSVAEAGPRKVVYISCGPETLARDLKIFARN
                     GYRAREAWGVDLFPWTGHVETVVLLSRKTPDDTIEVDLDLDELDITAAESKATYQEIK
                     DYVLKEFGLKVSTLYISQIKRKCGIDVGEHYNISQKENQKVPQCPKEKEDAIRAALEH
                     FAMI"
     gene            40086..40457
                     /locus_tag="ACZPCR_05995"
     CDS             40086..40457
                     /locus_tag="ACZPCR_05995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008373556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HIR1230462.1"
                     /translation="MKSLFEEMGGTYTLGADGMYYPDLELPEEEPHYGKYGRMRLRYL
                     KEHHKMLYNTLLLDGELVKHLNEVDDTANQRMELLTLQMQEQQGINEALKARDQMAWV
                     GACNNIRNAAEEIVLNELICC"
BASE COUNT        10662 a         9112 c        11726 g         9124 t
ORIGIN      
        1 cagaggtgta tgggctgaat gatttttata ttgtttccaa aaagttcgag tggcttatca
       61 gcgaatgcca tgaagacgta gtttcttttg tgggagattc attggatctt tcatgttttg
      121 acgaacagta aatctaaata tggaatatgg agaataatac gcatgatgaa gtatagaact
      181 ttacatgcag aggaaatctg cagagagctg tttaaagatt ttatccggca tcagattgtt
      241 gaaaaatgct ggcgcaggga aaatggaacc tgggaaatta aagatgcgcc gtttgtagac
      301 gattggacgg aacaggatta tcaggtttta atttcctgcc tgaagcatac ggttttgtcc
      361 ggcggatttg tatatgcagc gttttatgat ggaaaattaa aaggatttgt ttctgtggaa
      421 tcagagctgt ctgacgatga acacagatac tgcgacttgt ccagcattca tgtatcagag
      481 gacatgagaa acagaggaat tggaaaatcg ctctttctgg cggcgaagga atgggccagg
      541 aaaaaaggcg ccaggaagct ttacatatcg gcccactcag ccgtagagag ccaggcgttt
      601 tatcagtcaa tgggctgcac ggaggcagag gtttataatc agaagcacgt ggaagcagag
      661 ccctatgact gtcagctgga gtgtgcgctt tagacggaaa aaccgtgaag aaatcggaag
      721 ttattgatgc ggctgcattc agctttcatt aaacattagt gaggctggat atgggaatga
      781 taaaaaatga gataccaata ttggagtttg atacggaaca aacagcagtc ataagtcctg
      841 ttcatgaaaa tctaaatctt aagcttccga aaaaatgtgt ctttgcattt ctcggcgatt
      901 atatagagga gtatgctgac aaatctgata cgagacaagt atcatctttt atcagcgcaa
      961 ccaagagata tcctatttat gtaacacaat ataagggaga ggagattgtt ctctgccagg
     1021 cgcctgtggg tgcggctgcc gctgtgcaga tacttgactg gctgattggc tatggggttt
     1081 gtgaaattat ctcagcaggc agctgcggcg cgcttgaata ttttgacgaa ggtacatttc
     1141 ttgtgccaag caaggcattg cgtgatgaag gtacgtccta ccactatgct cctccctcgc
     1201 gctttatgga aatcaatgaa agagcaaaaa aggccattga gaaaaccata gtggagcaca
     1261 acatgaaata tcaagaggtc attacatggt ccacagacgg tttttttcgt gaaacaagag
     1321 aaaaagttga gtatcgcaga agcgaaggat gttcggttgt ggaaatggaa tgttcggcgc
     1381 tggctgcatg tgcggctttc agaaaagcca tatggggaat gctcttatat acagcagaca
     1441 gtttggctga tattgctcaa tacgatgagc ggcattgggg cggtaatgca tatgaatatg
     1501 cacttatact gtgtctggat gccgtattgg ccatatagct ttatgtgctg ccttccccca
     1561 gccttatcta aaaagcggta taggaatgct ttccagcggc tttcagcgga gtgtgaaaac
     1621 ttttctatac cgctctgtta gacctgcccc gtctccatta ccatgtaata atccggtcca
     1681 gcagctcttt ctgttcggcg cttgagcggg tcaggtaaat tctggtagtt tcaatgctgt
     1741 cgtgtcccat caggtctgcc aggagagcga tatcgttata ttttttcaga aaattcttgg
     1801 cgaatcggtg ccggaaggag tgggggtaga cggtatccgg atcaatgtgg tagcggacgg
     1861 ccaggtgctt cagctggatg gcaacgccgc gggaggtgat tacctggccg cgatgattta
     1921 agaaaataaa tccgctggta acgccttttt ccccaaacca ggccagggct tcgtcgcaga
     1981 ggcggcgggg aagatagagc cgccgcattt tgccgccctt tgtgtagaga tccaggcgtc
     2041 cgctttttaa attttccact ttaatctgaa gcagctcgct gattctggcg ccggtagccc
     2101 ccagaaagcg gacgacaaaa taccagtaga aattgtgatc ctgccggaga cggcgcttca
     2161 gcttttcgta atctctctgg gagatgacgc agtccagata ggtacattgc tgctgtctga
     2221 ccggttccag gcggaaggag aaacgcagac tgtccagaaa gcagttcaca gcgtaaatcc
     2281 gggcgttgac tgtgttgatc cggtaatgat ccagaagatg ggcgcggtag gcgcgcagat
     2341 tagcgggatt taaccgactg tagagggatg cgtaaagccg gatggcgcag agataggagc
     2401 gtatggtatt tgggcttttt cccttttgtt ttaaataagc tgtaaaaggt tccagacact
     2461 cgtccagatt cagatccata ttcacctacc agtccaccac cttgttgaca atttcatact
     2521 gttcattgct ggaacggcgc agataaatcc gcgtcgtctc tatggtttta tgtcccagaa
     2581 gatcggaaag cagggaaatg tccccgcatt tttcaatgaa gcttttggca aaacggtgcc
     2641 ggaaggagtg gggatgcact acgtcaggat tgattccata caaaacggcc agggttttca
     2701 gctgtccccg gatgccggcc ggagtaatgc ggcggccgaa gcggtttaaa aagatatctc
     2761 ctttccgtat tccggctgcc tgaagccaga gaagagcgtc ggtgcggaga gcctttggaa
     2821 tataaatcct tcgcgcctta tttcccttag aatagatttc cttaaagcct ttctggacgt
     2881 cctctgcctg aaactggacc acctcgctga cgcgggcccc ggtagccgcc ataaagcgga
     2941 ttaaaaaata gtagagatac cgtttgtccc gcagcaggca ggattttaaa tattcataat
     3001 ctgcctcgct gatgacgttt tccagataat ttttctgctg gatccgcacg agaggcagtt
     3061 tttttgattt ttcccgggta aattccagat aagcgttcag cgcccgaagg cggagattga
     3121 cggtctgagg cttataatgc tctaagagaa acaccttata caggtggagg ctggagaaat
     3181 cagcctgatg gtagcggcag agaaactggc gcagggcata ggagtagacc tgaaccgtgt
     3241 tggcggccat gtctttggaa atcaggtatt ggcgaaactc actgatttgt aaattgactg
     3301 cgttcatctg actggaaaga cgttcttttt ctgtctcagt caggagagaa gacggcaaag
     3361 cgggttggac gggaggaagc tggctgacag gtgatgccat aaaaaactcc ttttcattct
     3421 aaaatttcga tttctgtagt tcagtttcag ggtttttagt ctatctttca gtttttatat
     3481 tccaattgtg ggaattaccg tataactata acattccgct gtttgaaaat caagactgga
     3541 agaggaaaac aagcggaaaa caagggcttc ttttcttgca cccagcctgt ttaagtgata
     3601 tactaaatca gtatgtaact agacttgaaa taatcaacag ggagaatttt atgagcagtc
     3661 atctgattcg gccggcggca gaggagaaac gcccctggcg ctatatggag cttgcggcca
     3721 gcgtttacac tctggcgctg ctgtgcatct ttccttttgt ggtgcataac aaatatttcg
     3781 atattcttcc cacaaaatat caggcctacg cggttctcac atgcgcggcc ctgattttca
     3841 ctgtgattta tctgatcgcc agcggagcgg cagtgcgtgg gattcagtcg cttcgggacg
     3901 ggacctggaa agggcattta agctttgtgg actggagcgt tctggccttt gaagcgctcc
     3961 tgattttctc gacgcttcag tcggagtttc catatgagtc tttctgggga aacgaggggc
     4021 gctatacggg actttttacc atgtcgctgt atgtgttctc gtattttttc atcagccgtt
     4081 ttctgcggtg gaagcagtgg tatctggacg cgtttctggg gggaggaata ttagcctgcc
     4141 tgtggggaat taccgactat ttccgcatgg acatttttca ttttaaggag aggattgcgg
     4201 cgagtcctga cacttttacc tcctccttcg gaaacatcaa tacctacacc atttatgtgg
     4261 ctatggtgat tgctgttgcg gcggcgctgt ttgtgacttc caaatcagtg gggcgttcct
     4321 tctattatta tatctgtttt gtgattggaa tgtttgccat cattatggga gtgagcgata
     4381 acgcgtacct gtctctgggc gctctgtttg cccttctgcc tctctatacc tttacaaagg
     4441 gacaggcagt ccggcggtat gtggtgctga cagccacagt ttttacggtt gtccggtgca
     4501 ttgcgtggat taatacggcc tacgcggaca cagtaattgg aattgacagc ctgttttctt
     4561 tcctggcggg acatgataag ctgatggtcc ttgcgtgtgg gtcctgggcg tttgcggccg
     4621 ctttatatct gctgaaattt gcagtgaaga gggagccgaa agcagttctt ctgggactcc
     4681 gcgtggcctg gggcgtgctt ctggcggctg tttttgcagc ggcgttctgg attttttacg
     4741 acgccaattt tgcaggtcat caggacaaat atcaggcgat tgcaaagtat attgtgttta
     4801 atgacaactg gggtacgaac cgtggctttg cctggagaat ttcctgggaa aactttaaga
     4861 gctttcctct gattcataag atattcggct ttggcccgga cacctttgga attattacta
     4921 cctttaataa ttacaaggaa atgagcgaga tttaccatgt tacctttgac aatgcccaca
     4981 atgagtacct gcattttctg cttaccatag gagcggccgg ttttgcagcc tatctgtcct
     5041 tcctggtatc tgcttttgtg aagatgacaa ggagagcggc ggacaacccg ctgattctgg
     5101 cgccgctttt ggcctttacc tgctacagcg tccaggcggc tgtcaatctg aacgtgccga
     5161 ttacggcgcc gttcatgtgg gcgtttttag ctatgggact ggctctcgtc agaagggacg
     5221 ataaacagaa aaaatcagaa gacgcaggcg cagagaaatg agaaggatgt tgtaaattac
     5281 catgtttgag aagtatatgc caaaaaacaa aagagccaga atgctgattc tgatggccgc
     5341 ggacattgcg gctattcagc tgtgttcctt tctggctctg ctgatccgtt ttgatttgaa
     5401 tattgccaag ataccggcag agtacagcgc gaacgtgctg agctacgggc tgattcacac
     5461 agcgctgacc atcgctttct ttttcctggc ccatctctac tctaccatgt ggagtgtggc
     5521 gggcatcagg gaggtaatca ggattgtcat tgcctgcgga ttttccacag tgacacagat
     5581 agcaggcatg acgcttatgc agtattttat gccgagaagc tattatatta tcagcttttt
     5641 cggactctgc atcacagtga ctggaatccg cctttcctac cggattaaaa attcactgtt
     5701 tccgtcagga aacagaggtg gagatcggat tatgatcgtc ggagcgggaa cctccggttc
     5761 cgtcatttta aaagagatga tgacaagccg ccatacgaac ggtacggtag tgtgctttgt
     5821 ggacgacgat ctgaataaaa agggaaaata tttaaacggc gtgcccattg ccggatccag
     5881 ggaggacatc cccggtctgg ccagagagta ccgggtggac gagatctatg tggcactccc
     5941 ttccgcgcct gccaaggaga gaaaaaaaat cattgaaatc tgccgcgaga cagactgcag
     6001 gattaaggtt cttccaggaa tttaccagct gttaaacggc gaggtcagcg tggcaaagct
     6061 gcgtgaggtg cagattgagg acctgttagg ccgtgatccg atccgggtaa atctggatga
     6121 gattatggga tatgtgcagg acaaggtcat ccttgtcacc ggaggaggcg gctccattgg
     6181 aagcgagctg tgccgccaga ttgcaggcca caagcccagg cagctgattg tcttcgacgt
     6241 gtatgagaat aatgcctacg atctgcagca ggagctggag cggacgttcc cggatctgaa
     6301 tctgacagtg ctcatcggtt ctgtccggaa tacccaccgg attgagacgg tgtttgagac
     6361 gtaccgccct gatattgtat accatgcggc tgcccacaag catgtgccgc tgatggagaa
     6421 cagccctaac gaggccatca agaacaacgt gttcggcaca tacaagaccg ccagagcggc
     6481 aggcaggtac ggagccaagc gttttgtcct gatctctaca gacaaggcgg ttaatccgac
     6541 caacatcatg ggggcttcca agcgcatgtg cgagatggta gttcagatga tggaccgccg
     6601 atacaagaca gagtttgtgg ccgtgcggtt cggaaacgtg ctgggaagca acggctctgt
     6661 cattccgctg ttcagaaagc agattgcaga gggcggtccg gtgacagtca cccatcctga
     6721 tattatccgg tattttatga ccattccgga ggcggtttcc ctggtgctcc aggcgggcgc
     6781 ctacgcgaag ggcggggaga tcttcgttct gaacatggga gagccggtgc gcattctgga
     6841 cctggccaag aacctgatcc gcctgtcagg atacgttcca aacgaggata ttatgattga
     6901 atttaccgga cttcgtccag gcgaaaagct ctatgaggag atgctgatgg acgaggaggg
     6961 aatgcaggat actcctaata agctgatcca tattggaaag cccattgaat ttgatgagga
     7021 agagttccag aagcagttag acgagcttta tgaaatcgca aatcaggatt ccgaccacat
     7081 taaggaggca gtccagagga tcgtgcctac ctatgtgatc aagaaagatt cctgataaaa
     7141 gacagacaga ttagattgat ttttcaagaa cccaacggcg gaggccccca tattttaagg
     7201 cctccgcaat ttttttatat ccgaggcgct gaaagttgga gaggctgtag tggttatccg
     7261 ggtggacggt agccatgaaa tggcggtaac ccgcggcggc ggcagccttt tcgccctcaa
     7321 tcagaagctt ccgctggagg ccgtatcccg taaagcctgc ggctacggct actgtttcca
     7381 tatgggctac ctgcataagc tcttgtccgg agaggctaag ataagttccc aggttatctt
     7441 ctgtggggtc tggaaaacga atcaggagaa acgcggccag actgtcccgg gcagcttggc
     7501 ccgctccacc ttccggcccg tccgggcagg ccttgagaat caggcccctg tctttgatat
     7561 gggttttgat aaattccaga ctgtcaggaa aaaaccagtc tttattctgc acagagaagg
     7621 ccgtgtccgt catcaggcgg taaagcgcag ggcagtcctc aggcacggct gcttgaatag
     7681 aaaattggag tggtaaacga gtcatggttt ccttcctttc tgctgctttt ctgctgctat
     7741 tctactacat tgaacaggaa aagaaaatac tttatcatgt tttctcctag aagcgggtgg
     7801 taatattttt attatcccaa agggggtaat aaaaacaaag gagaagaaag atgaaggaaa
     7861 tcggagagat gagagcagaa gacggcagag aggggcctgc atttatgacg gttggcggcc
     7921 tctgcgagga gtggctgcgg tcggtgaagc cgatggtgaa gcccagcacc tacgcctgct
     7981 acctgacaat ggttgagaag catatccggg gagagctggg aaaagtgcag gcggcggatc
     8041 tgacgaatca gatgataatg gattttatac atagcaggca gaagcaggga ctttcggcgg
     8101 ggacagtccg gcttctttta tttttgctga aaagcattgt gcaggcaggg gaggagatgg
     8161 gggcatgccc tggagaagca ctgtatctga agcttcccag gcaggcggga aaaagaaagg
     8221 agattatgga gtgggaggat ttccacaaga tggtttccta tctgttaaac tccagaaaga
     8281 gctttgagct ggggcttttg atttccctgg gaacgggaat cagggtggga gagctgtgcg
     8341 gcatgcgctg ggaggatatt gatctggata cgggagtttt gaaggtcaga agaaccgtgt
     8401 cccgcatcag aaacgtagag gaagcgcagg cggcagttcc gggagggaag actatactgc
     8461 agatagggac gcccaagacc ggttcctcgg tgcgggatat tccccttcca ggatttctca
     8521 cagaacgcct cagagagcgg ttctgtgagc ggcggttcag ccctcagacc tatgtgctca
     8581 caggaagcgg gcgggtgatg gagcccagaa gcgttcagcg gagatttaaa aatctcctcc
     8641 ggcggtgcgg gattaagccg gtcagcgtcc attccctgcg ccactccttt gcgtccaagt
     8701 ggattgagca ggggctggac agcaaagccc tgtctgagat tctgggacat tcctcggtga
     8761 agataacgat ggatatctat gtccacagta ccatgaatca gaagaagaac tatatggatc
     8821 atgttttaga aggaattgta attgatcaaa ggtcttctct gtgataagat gaatagcaga
     8881 gcattttaca gttaggagga ttagaatgga gtctcaatac aactacgagc aggagatcga
     8941 cctgaaggat ctgatgtttg ccgtccttcg caaatggcgt ccgattatcc tgattgcgat
     9001 tgtttttgcc gttttgctgg gcggtatgaa gggcgccggc gcgctgaagc agatgaagga
     9061 cagcgagtat ctggcagcta agcagcagga atatgacaac agcatggatc agtacgcgat
     9121 ttccaaggca agccttgaaa aagaggtgga gaatattaag gccagtctgg aaagccagaa
     9181 cgagtatatg gaaaaatcgg tgctgatgaa tattaatccc tacgatgagt atgtgacagc
     9241 agcggctttt tatgtgggaa ctgattatca gattatgccc ggtatggcct atcagaatcc
     9301 caatacagct tccagcatta tgcaggcata tatgtccatg attcagaacg gagatatgta
     9361 caattatgtc ttaaacggca tgagtgctcc actggatcgc agatatcttc aggaactggt
     9421 gacagttacg cctaatttag agaacaatat gtttgacatc cgcgtaatca gcagctctga
     9481 ggagggcgct tccagtatca tgaagctgat tatggattcc ttaaacgagt acagccaggt
     9541 gattacccag gcgattgggc cccacactct gaaggtgatg agcagctccg cccgtcccgg
     9601 cgcagatatg gcgcagacgc cggagatgat tggcgccgga ggaagccctg acgtgtatac
     9661 gaccgtggat ctggaactgg agaagaaaca gcaggagcag tctgccagaa tcgcagagct
     9721 gaaccagagc ctgacggata agacaaaaga actggctgat ttaaaggaac cgtccatctc
     9781 tcttccacgc aaggggggag cggttaagtc agcagtcaag tacgctgtgt taggaggcgt
     9841 cctgggaggt ttcctgtcag tattctttat ctgtgtggca tttttaatga gcgataagct
     9901 gggcagcgat aaggaactgc gccgcagata tggtctgatg attctaggcc tgttcgatga
     9961 cgcaggaaga aaggggctgt tttcctttgt ggacagattc ttagaccgca tggagggaac
    10021 ggcaggcaga aagatggaca aggaaactgt ctgcagcgta gtggcggcta acgtgatgaa
    10081 ctatgcagga gatgcaaaac agctgctttt agtcacgtct gcgcctgacc tggacttaga
    10141 ggcagtaagg agcgacattg cgcctgctct tacagatctt ttcgtgacag caggaggaaa
    10201 tcttgacagc caggctgacg ccatcagaaa ggccgcgtcc tgtgaggctg tgattctggt
    10261 agagaagcgg aaaagctcct ccttctccgg cattgagcgg gagcttgata ttgtgagaag
    10321 tcttgacaag aaggtactgg gctgcattgt tctgtagcat tgccgtttcc gtgtttcgtt
    10381 tctgggtttc agaccagact cgtcagtttc tgtcgaaact tgcggtcgat tttcctgtca
    10441 ttctctcctg gagaggtgta taatggtaaa agcagtctca ggaaagcagg aggggtagaa
    10501 atggatgcgg cagcacagtt ggaagaactg atgattgaag tagaacacct gaaggatgag
    10561 aacgaaattc tcttcgatac ggtagttcag atgaagagct cgttggacag gctgatcaca
    10621 gtctatattg gcagcggcaa acagaagatg agacaggcag ggatgtagca gaaaacagaa
    10681 taaaaaagaa caaatccggc atcagcggca ggaaaatcga agaagatgga atcctgcggc
    10741 tgcatgccgg ttctttttta cacatatcgg tgagccgctg gctgcgcccc ttcacaggct
    10801 gcgccctttc acagtaagag gaaccatatt ccgacgactt taagtggagt aaggaatatg
    10861 gttcctctta ttgtctcccg catctttaag gggagtaagg aattctttct tttcctgtct
    10921 aacgctcctc tccctctcct ctcgtcagct tccagattgt atcgtgcatc caggccacag
    10981 tgtcggagag ctttctgttt tcggctttca gcgtttcgat ttcctgtttt aattcctgaa
    11041 tcgtttcagc ctgctttgca atctcagccc ggctgttgaa gcgcctggcc tgttctgtga
    11101 tgcgctgcac tacagaggag tgcggctccg cgccgtcgag gatctggctt ccaatcagct
    11161 gatcccgcat tctatagtcc agatccataa actgctggca ggacatggga agctttgtca
    11221 tatggatgcg gcaggacggg cagacggccc tcctggggat cagataatac ccgtagtagc
    11281 cgcagtgcgg acagtaaaag acagttagtt ccttcatgaa aatctccttt tgcattgatc
    11341 gatatctaag actttgaagc tggtctccta ttagaaaacg aagaaaacag gagaaatata
    11401 actaaaaaat aaaaaatatt tggaaatttc tgcagaatat aaatcgcagt ctgtgatatg
    11461 tatattctcc gctgtgctgt gtgaatcagc aaaaagcggc gccggcagag agagcatggc
    11521 ccgaactctg ccggtgaatg gccgcaaatc aggagaggaa ctgctttcgc agccctctcc
    11581 tgtgaacgga tgacttatat attttactgg atgattccgt ttgtgtcaac tgtccacaca
    11641 gtatcattgg aatctttgta atctttaaag ccctttaaaa gctcaggctt tgcgtcggaa
    11701 gtggaggaag aggaggcttt ctggatggtt ccgctggtgt ttaccagata agtcctgtct
    11761 cctgcggcca ctggctcata gcgaagctcc ggatcggctt ttttcatcag gccgttgacg
    11821 taaacgcggt tgtctctctc gcctgtgtag ccctggcctt ttttagaacc gcttgggtag
    11881 aagtaccagg tctggttctc ctcagcgtcc tcgtcgtaga tggtctgctt tcctgtcttc
    11941 atggctccat cgtctccaaa gtagtagacg gcctcaccgc ctcccttgac agccagagtc
    12001 tggacaccag tctgcatttc gcctttttca ttgaaggcgt accgctccga gttgatgttg
    12061 aacagctcaa gcccagcttc ctgagaatag tagggctttc cgtttttaaa gtagaagtaa
    12121 tactcttcgc cctcctcgct gattccctcg atgccttcaa tctgatacca gccggaagcc
    12181 ctctttccgc cctgctcctc atcgtaatac tgataggaag ccggggagtc tgcttcgccc
    12241 tcagcggtct tctccgtctt cacccagcct gtctgcatct ggccgttttc gaaggtgtaa
    12301 aaggcgccgt cgattttgcg gtcaatctga ttgacaacca gctttccgtc ctcgtcgaag
    12361 tagcaccaga ttccctcgtc atctgtgtct tctgtgatat cttccagcag aatccagccg
    12421 gttttccgga ctccgtcgct ttcttttcca agatagtaga cagagccgtc cagctccaga
    12481 acgccagtct gcataatgcc gtcctcgtcg aagtagtgcc agttgttctg aatcgccatc
    12541 cagcgggatg tgacaatctt tccgttttta tcaaaatagt tccattcctg gtcggacgca
    12601 gagtccgggg agtcgtaggt ttcctctcct tccggagata cccatttatt tttaaccatt
    12661 tttccttcac tgtccacata gtactcgtcc acccgctggt tgacggttac gtttccgtcg
    12721 tcgtccaggt agtaccagtc gcttcctctc ttcttccagg tgttggactc cagatagccg
    12781 tcctcatcgt agaaatgcca ttcgctgtcc tcctgtaccc agccgtttgc agcgtagacg
    12841 tttaagagaa agctgtcgtt taagacatta ggggctgcca tggacatcat ggcggcagca
    12901 gataatacag cgatcagttt agttgttttt ctcatggaat gttctctcct tttttgtgaa
    12961 tgaagtgtgt ttgaaaatcc atcgttgcat tacagcgctt attatagcgt ggcatgggag
    13021 agaatgaaag tgaaggttac tggaagcgct ggaaggagtg ggaaaaaaga aacagagcct
    13081 taatggctct gcttctcctc ataccaggaa tcggtgataa actctgcctg gaagcttccg
    13141 gagagctttt tcaggacgtt tttcacatag gaattgagat tcatggattt ttcttttccg
    13201 attcggtagt ccatgtcgga gttaaagtag ttgtcgcctc ccacgctgta gccgtcgaag
    13261 ccggcgcagg ctgcctggga tacccctgct tttaccagga cgtttaacag catgacgaag
    13321 gaattgtcaa tgatttccgc atctctgtca atgagggagt tgtagttcag ggtgtagtca
    13381 aaggatccgt ttacattggt cacattggaa gtggcaatga cgcggaccgg ggacgcctgg
    13441 gcgtgctcct gctccttttt aagctccagc agacgggtag tcagctgcac gtaccgcctg
    13501 gaattgctca ggaaagcgta gtctaccggg atattctccg gaatatagtt gacggcgatg
    13561 acaaccgggg catgctcttt tatataccgg tcgatccgat ccctctgaag ctccatgttt
    13621 tttccggggc ccagaagaag aaggggcttt ccagaccact ccctggagag gcgttttaaa
    13681 tcgtcctcat cgctgcactc catgttctgg tagtttaaat acaggttttc aatatagtcc
    13741 ttgtcgtaca tcagcttctt ttccggctcg atctgtccga gaatcacatt taaggacttt
    13801 aaggacaggg tgtgtttgtc catcaggaat ttgacatagt tcggatggca gttgttggag
    13861 gccgcgatgt agaagaagag gctgtagccc caggggcttt tctcaaaaaa cggaatgata
    13921 ttgatatcaa tggcctccag catctggctg gtgtcgtagg attttccata gtggagattc
    13981 atgtgcatgg aaatcagctc cacaggcaga ttcccggcgc tctttcccat gccgtagagg
    14041 gaggcgtcca ccagaacggt cctgtttacc ggcttgctga gcatttccat gctgttggcg
    14101 taggccatct ggaaattgtt gtgggaatgg tagccgatgg caatctcagg atttaagttg
    14161 tgatccagga tctcgaaata gtggagcagg ctgctctggt ggagcaggcc gtaggtgtct
    14221 accatggaga gggcataggg gtttaaggcg ttgaccaggt cgatgagatc taaaagctcc
    14281 ctgtcagagt agcttgtaat ggaaactgcc tggacaaaga cctggtagcc cagagccttc
    14341 acctgggtac agaaggccag agcctccttc ataatgtgct ttttaaagat gacgcggatg
    14401 ccgtccagac agctttcgct gcagggagcc aggttttcaa tggcgcaggt tccatagtcg
    14461 atcatgccta ccagcatggt gtttttcttg tccagactgc cgaacagccg gtctgcgctg
    14521 gcagtgtccg gcataatggt gcggtttctg tcaaagggac gccggtcgtc gagaaagccc
    14581 acctctaaaa tatctactcc ggagctgatg aggcgctcga agatatttac catgttgtcg
    14641 tgtccgaaat tccagtcatt gacatatcct ccgtcccgga gagtacagtc gagaagcttt
    14701 acctgtttca tatgattacc gtcctttcac taaagaaact tgaagaaagt ctgcgatttc
    14761 tcctgtatca gctgctgtaa atacaggaga gaagtgtttt tcccatgcct cttttgtttt
    14821 atagccgaag ccaaaggtga cggccataaa gtctgttccg gcctccttcg cgccgtttcc
    14881 gtcggaggag gtatccccga ttaagagcgc ctcggagggt tcaagactca ggccgctgag
    14941 gcattttcgc agcacgtcgg tctttgtcat cctgctttca aaatcgctgc cgcagatgag
    15001 atcgcacagc tttgcaatgc cgaaatgctc taaaatggtg tgagcgtagt cctctcgctt
    15061 cagcgtggcc acgcccacca gaaagccctg gtccttcagg gcctttaaaa gctccagaat
    15121 gccgtcgtag ggcttggcct ttaaaagatc cttgttctta tactgctggc ggaacacctc
    15181 cgttgcctcg tccgcctcct gatccgtcag cccgtaatgc ttcatcaggg aacgcttgac
    15241 aggggggccg ataaaggtga gaagagtctc cagaggcagc tcccggtagt tcatggtctt
    15301 tattgtgtgg cggatgcttg ccagaactcc ttccgaggtg tccagaagcg tgccgtctaa
    15361 atcgaagata attcctttgt acatgataat cctccattga ttgtgttcag ttgttctgcc
    15421 atcaggcgca cctgccgcag atcctttttt gtgtccaccg acagggacgg gtgccccgta
    15481 ttgacaaagt atacgggcac attgtgttcc agaaagcgga gcagatcgca ctcctcgatg
    15541 gtctccagag gccccttcgg cgtgtctgta aagaaatcaa gcgcttttct ggtgtacacg
    15601 ccgatgctgg caaacttctg ataggtaaaa ttcagctctc ccttgggata ggggatggga
    15661 atgcgggagg tgtaaagccc acgcccgtct tccccgcaga ccaccttaat attagcggta
    15721 tccatggcct cggaggggga gagtacaggt gccatggcgt ttaccacgaa gagagcgtct
    15781 tctctctcca ttcggtcaag ggccgcctga accacaagat cgatatcctc ccctgtaagg
    15841 aggggctcgt cgccgccaat cataacgtac aggtcagaag gaatggaggc tgccgcctcc
    15901 cgaagccggg acgtgggatt ttcatggctc ggatctgtca tcaggcaggg aatggagagg
    15961 gattcgcagg cctcttttat gttggggctt tccgtagctg cgaaaatccc tgtgagcaga
    16021 cgggactctg aggcgtgctc gaatacatgg agcagcatgg ggcgtccgtc taagagagcc
    16081 agaggctttc ccggaaagcg ggtggagccg tatctggccg gaataatgcc agtaattttc
    16141 atattcatct gccagccttt ctaaaaatct cacttcatta taaaaagaat ccagttaaaa
    16201 gacaaggaaa actggtaaaa accatgaaat cttgtggcaa atgtaagaaa aagtttaata
    16261 ggcatttatg ggaaattgtg atatactgag cgtgggtttt tagaaactta aagatttgtt
    16321 cacataactg taacatatga aaaaatagaa caagccggat tctgaatccg gaaggagagt
    16381 aaggagagca tcatgcggat aaaggtatcc aactatatcg cccagaagct tttggaggcg
    16441 ggaattaagg atgtgtttat gattaccgga ggaggcgcca tgcacctgga cgacgccctg
    16501 ggacatcagg agggattaaa ctgtatttat aaccaccacg agcaggcctg cgccatggcg
    16561 gccgaggcct atgccagaat tcacggacag attgcggcag tctgcgtcac cacaggtccg
    16621 ggaggaatca acgccatgac aggcgtggca ggcggtttta tggactcgat ccccatgttt
    16681 atcgtttcag gacaggtacg ctacgatacc atgtcacgca gcacagatct gcacctgaga
    16741 gctatgggag accaggagtt tgacattact gcctctgtgg ctaatatgac gaaatatacg
    16801 gagatgatca cagatcctat gagaatccgc ttctgcatgg agaaggccct gtacctggcc
    16861 tatgcaggcc gtcctggccc tgtgtggctg gacgtgccgt taaatgtgca ggcagccatg
    16921 gtggagacag aggatctgac tggcttcgat ccggcagact acgaggcggg aggaaccggc
    16981 tgggcgaaaa agagtgaagc cgagattcct atggatacag ccggccaggg cgagtaccgt
    17041 gcacttcttc ctaaaaaggt ggagaaggag acggccagag agattattaa gaaaatccgg
    17101 gcggccagac gccctgtgat caacgcagga aacggaatca gaatcgcagg agcccacgag
    17161 gtattcatcc gcgtggcaga ggcgttacag atcccggtag tgacgggagc ggacagcatt
    17221 gactgcatct gggacgagca cccgctgtac accggaaaag gcggaaacgt gggagaccgg
    17281 gccggcaact ttgccatcca gaacagcgat ctgctgcttt ccctgggaag ccgtttaagt
    17341 ttccgccagg tgggctaccg cttcgataca tgggccagag aggcctacac aatcatcaac
    17401 gatatcgacg cggaggagct gaaaaagccg acgcttcacg tggatatgcc ggttcacgca
    17461 gacgtgaagg atctgctgga gactatggag gaggttctga aggaagaaga gctttccagg
    17521 gacgccatgg acggggagac acgggaagct caggagcagt ggctggctca gtgcagaacc
    17581 tggaaggaga agtatccggt tgtgcttcca cgccatatgg agggaggcac ggagaccgag
    17641 gccaacgtgt acgcctttgc ccacgaactg agcgcaaggc ttttggaaga tcagattgtg
    17701 gtggtgggca acggatccgc caacgtagtc tgcggccacg ccaacattat gaaaaaggga
    17761 cagcggttta tttccaactc aggaatcgct tccatgggat atggcctgcc tgcctccatc
    17821 ggagcctgca ttgcaggatc tgaccacgat attatcctgg tgacgggaga cggaagcatt
    17881 cagatgaacc tgcaggagct ccagacggta ataggaagat ggctgcccat caagattttc
    17941 gtgatcaaca acggcggcta tcactcgatc cgccagacgc agaagaattt cttcggcgag
    18001 ccgttaatcg gaatcggcgt ggacagccgg gatttaacct tcccaagcat ggaaaagctg
    18061 gcgtgggcct acggcttccc ctatgtgtcc atccacggaa acaaggagct ggacgagaag
    18121 ctggaggagg cgttagctat cgacgggccg gtgatctgcg aggtatttgt gacgctggac
    18181 cagaactttg agcctaagtc agcggccaag aagctgccgg acggaacgat ggtatccccg
    18241 ccattagagg atctggctcc gttcctttcc gacgaggaga tggatgaaaa tatgatcatc
    18301 ccaaggattc agaaatagca ggagagaaag gcggccatat atgaagatag ttgctacagg
    18361 agcgaccagc tttgtgggaa gcggggctgt gaaggccctt ctggagcgcg ggcataaggt
    18421 ttacgcagtg ctgagaaagg gatcctccaa ggcagacagg cttctgataa acggagccat
    18481 gccggaaaac ctggtgattc tggaggagga tctgggaagc cttgagcgcc tggcagagca
    18541 gattccagag ccctgcgacg tgttcctgca tatgggatgg aagggggcgg gaagcgattc
    18601 caggtcggcc gcggccatcc aggaggaaaa tgccaaagat tccctgaatg ctgtgcaggc
    18661 ggcgaaagct ctcggctgca gacgtttcgt tttcaccggt tcccaggcgg agtacggcgt
    18721 ccacgacgcg ctgatgaacg aggagaccgg gtgccgtccc acatccccct acggggaggc
    18781 gaagcttaag gtgcggattg aggcggaggc cctctgcaga aagctgtcca tggactacgg
    18841 tcacgccaga attttcagca cctacggaat cggcgatcac ccctggtccc ttctctccac
    18901 ctgtgtaaac accttcctgt caggaggcgt gatggagatg ggggcctgca cccaggactg
    18961 gaatttcatg tacattgacg acgcgggaag ggctgtggcc atgctctgcg agtatcagaa
    19021 aagcctgatg gagcagggat gcgtctacaa cctgggaggc cccatggacg agacaggccc
    19081 tctgaaacac tttgtggaaa cggtgtacga gatgtgcgga aggaagggaa gctgcgtgta
    19141 cggagtgaga aagcctaacg cggagggcgt cgtgaacctg attcccgatc tgacgaagat
    19201 gaagcgggtg atcggatggg agcccagagt cagattccgg gacggaatgg cccgggtcat
    19261 tgagagcgtc cgcccatctt aagaaaaatg tcccttgtaa attcctccgc ataagattag
    19321 aataatagaa aatcctgcag gacgggcctg gggcgtacca tgcccgttct gaagagggac
    19381 aggaagagag aacgattgac aatgaaaaaa atcagcattt taattccctg ctacaacgag
    19441 gaagagaatg taggacccat cagccaggct gtggtggaga ccatgacaag ggagctgccg
    19501 gagtacgact atgagctggt gtttattgat aatgattcca cagaccagac ccgccccatt
    19561 ctcagagagc tgtgcagaca gaatccgagg attaaggcga ttttcaacgc caagaacttc
    19621 gggcagttca attcccccta ctacggactt ctccaggtga cgggagactg cgtgatcagt
    19681 atggtggctg atttccagga tccagtggag ctgatccccc agtatgtgag agagtgggag
    19741 aagggctata agatcgtcat cggaatcaag acgggaagca aggaaaatcc cgttatgtac
    19801 tggctgagaa gctgctacta caagatgatc aaaaagctgt ccgacgtgga gcagatcgag
    19861 cattttactg gttctggact ctacgacaga gagtttatcg aggtgctgag acggctggac
    19921 gatccgactc cgtttctcag aggcattgtg gcggagctgg gctataagag gaaggaaatc
    19981 ccctatgtgc agcctcagag aagagccgga aagactcaca acaattttta ccgtctttac
    20041 gatgcggcca tgctgagcat tacctcctac acaaaggtgg ggctgaggct ggctacgatt
    20101 ttcggcagta tctgcgccgg tatcagcatt gcggtggctt tcgtgtattt gattttaaag
    20161 ctgcttcact ggaacgattt tccggcaggc atggcgcctg tgctgatcgg catgtgcttc
    20221 ctgggatctg tgcagatctt ctttatcggt ctggtgggag agtacatttt gtccatcaac
    20281 gccagggtga tgaagcgccc tctggtggtg gaggaggagc gcctgaattt tgacagcccg
    20341 gacgcccagg aaaccgagag ggagaacgag gagacggaga aagccttaaa gcaggagaag
    20401 aagcatgaaa tttaacgtag atgtggtgag aatccgcgaa aattccatac agctgaacgg
    20461 atgggccatc ggaaagactc cggaggccgc catttcctat gacgtggagg atgaaaatca
    20521 taagcatctg gagcacaagt atgtggccac cagaagagac gacgtcagcc agatttactt
    20581 tggaagcgtg attgacagag agtttggctt tgatatccag tttccctatg agaggggaaa
    20641 ggattattat ctggtaatcc ggggcgaggg ccgcagaatc cgggtcaaat acaatgaaga
    20701 tctgattgca aagcgcagca gcgtggccca caagaagatg cagaaaatca gggatctgat
    20761 gaatatggaa acggtccggg tggcctatga cttctggaag gagaacggac tgaaggccct
    20821 gatcaaaaag tcaaagcaca agatccaggg cattgacaac gactacgact acgccgagtg
    20881 gtacgatctt acaaagccca cagaggagga gctggcagcc cagagaacgg cagtgtttga
    20941 gtatatgccc aagctttctg tggtgattcc ggcctacaag acgccggagc ggtatttgaa
    21001 ggaaatgctc aactccattc tggcccagac ctacgaaaac tgggagatct gcattgcaga
    21061 cggaagcccg gcgggagaga gctgcgagcg ggtattaaag cgctacgcgg agcaggaccg
    21121 ccgttttaaa tatgtgattt taggagagaa caaggggatt tccggcaata caaacgcggc
    21181 tatggatatg gcggcaggag actttatcgt gctggcggat cacgacgata cccttcctcc
    21241 ccacgccctc tacgaggtgg tgaaggccat caacgagcat ccggaggcag acgtgattta
    21301 ctcggacgag gacaagatgg acatggacgg cggggcgctg ttcgatcccc actttaaacc
    21361 ggattttaac attgatctgc ttcggagcgt caactatatc tgccatctgt ttgtggtcag
    21421 ccacgatctg gcggccagaa caggaggatt ccgccaggaa tttgacggag cccaggacta
    21481 tgactttatt ttccggtgtg tggagtcggc gggacaggtt taccacattc ccaaggtgct
    21541 ttaccactgg cgctgccacc agaactctac ggccagcaat ccggagagca agctctacgc
    21601 tttcgaggca ggttcgagag ccattatggc ccactatgac cgtgtgggaa tccaggcgga
    21661 gcgtgtggaa aagggcgtgg actacggcat ttaccactcg atttacagga ttcagggaga
    21721 accgctggtc tctgtgatta tcccgaacaa ggatcacagg caggatctgg atctctgcat
    21781 ccgctctatt atggagaagg cttcctaccg gaatctggag tttgtggtgg tggagaacaa
    21841 cagccaggat ccggagactt tcgcctacta tgagaagctt cagaaggaat ttccaaacgt
    21901 ccgggtagtg aagtgggaga gagagttcaa ctactctgcc atcaataatt tcggcgtcac
    21961 ttttgcaaag ggagaatacc tgctgttctt aaataacgat acggagccca ttgagccgcg
    22021 tttcattgag gagatgctgg gactgtgcca gagagacgac gtgggcgtgg tgggagccag
    22081 actgctgtac caggacgaca ccattcagca cgccggcgtg gtcgtaggat tcggcggcat
    22141 tgccggccac acctttatcg gactgcacaa ggcggagaac agctatttcc accgggctat
    22201 gagcacccag gactacagcg ctgtgacggc cgcctgcatg atgagcaaga agagcctgtt
    22261 cgaggaagtg ggaggcttta cagaggagct ggcagtggcc tttaacgata ttgactactg
    22321 tatgaaggtg agagccgccg gaaagctggt ggtctataat ccgtacgctc ttttgtacca
    22381 ctatgagtca aagtctagag gtctggagga cacgccggag aagattgccc ggttcaaccg
    22441 ggagatcagg attttctcag agcggtggcc gaagattctg gaagagggag atccctatta
    22501 caacccgaac ctgaccctca gaaagtctaa tttcgctctc cgggatctga agaaggaggc
    22561 aatcggagag ccctataagc tggagatcta aggccttaac agaagagacc tggaaaataa
    22621 gaggaagata tatgactgcg actgtaactg tgattattcc caattacaat gggatgaaat
    22681 ttctggagcc gtgctttgag gccctgaagg cccagaccta caggaatttt aagattctgg
    22741 tggtggacaa cggatccagc gacggaagca aggagtggct gaaggcgcag ggcgtggaca
    22801 cgatttttct ggaggagaac accggatttt ccggcgcggt gaacattgga atcaaggcgg
    22861 ctgacacgcc ctatgtgatt ctgcttaaca acgacaccaa ggcggacgag tactatgtgg
    22921 cggagatggt gaaggccatc gagcggtcgc cgaaaatctt ctctgtcagc agcaggatga
    22981 ttcagatgta tcacccggac cttatggacg acgcgggaga tatgtactgt atcctgggct
    23041 gggcctacca gagggggatt ggacagagcg taaagaaata cggacgttcc aggcgggtat
    23101 tttccgcctg cgccggagcc gccatctacc gcagagaggt attcgagcag atcggttatt
    23161 tcgacgagat gcatttcgcc tacctggagg atctggacgt gggctaccgg gccagaattt
    23221 acggatatga caatgtatac tgtcctgcgg cagtggttta ccacgtggga agcggaacca
    23281 gcggttccaa gtacaatgca tttaaggtaa agctggcggc cagaaacagc gtatatttaa
    23341 attataaaaa tatgccgctt ccccagcttg tgttaaacgc ggcgcctctt gccctgggca
    23401 tggcggtaaa gcgggggttt tttaagaaaa tcggttttga gaaggaatat atggaaggcc
    23461 tgaaagaggg attttctaca gtgaagcgct gcaggaaggt tcccttttgc agagagcatt
    23521 tgaaaaatta tctccagatt gagatggagc ttatagcggg cctttttatc tatacatggg
    23581 aatttgcatc cagaaagctg tccggcagaa acacgcggga gagctgacgg agggtgcggt
    23641 taagtcagtt tcaaatacaa ggggatgatg aatcagatga attatgatgg agacgacgag
    23701 ttagagcgta tgcggcagag acgccagatg aggcgggaaa gccgccagga tccggaccgc
    23761 ttcggctatg aggacagccg ttacggggaa ggctcctacg agagaggaag ccgggcgcgc
    23821 cgggaggcgg agacctcaag aagcggcaga cagagcgcgg gaagggccgg agaacggccg
    23881 gaacgccgga tgagagaggg agagagagac agagcgcgcc aggacggcgg cagaacctcc
    23941 cagaaccgcc agagcagaac gagggataga gagagggagg cgtcaggcag cccgtccttc
    24001 cgttccggct acagcggccc taagaacagc cataaaggca gtcagagaag aaatcagaga
    24061 ggaggccgtg gcggcggctt ccagatggat cggagaaaga agattttcct catcgtggga
    24121 ggcgtgattc tggctctcat ccttttcata gccgcagcct acgcctatgt gaaccacaaa
    24181 ctgtttggaa atatggccag cgtggatttc gacgagaaaa aggtggagaa cctggattta
    24241 agcgaggagc agctggccca gatgaagggc cattggatga tcgcttgttt tggagtggat
    24301 tcccgtgaaa agggcggcga gatgaacgta ggaaagggag ctaacgccga cgtaaacatg
    24361 atctgcagcg tggatctgga gtccggcgag atcaagctgg tttccgtatt cagagatacc
    24421 tatctgaata tcagcgataa aaatacttat aataagatta acgcggctta tgccattgga
    24481 ggtccggagc aggcggtagc ggctctgaat aagaacctgg atctgaatat cactcagtac
    24541 gccaccttca actggaaggc agtggcggac gccatcaaca ttctgggagg cgtggatatt
    24601 gagctgagcg aaaacgagcg ttcctggatc aacgcttaca tcacggagac agtaaaggag
    24661 acaggaatcg gctcccacca gattcagaag gcgggactgg tccacatgga cggcgtgcag
    24721 gccgtggctt atggaagaat ccgctacggc gacactgact acgcccgtac cgagcgccag
    24781 agaatcgttc ttcaggcagc ctttgacaag gtaaagacgg cggactgggc aactgtcaac
    24841 aatgtaatcc agacagtcat gccgcagctg gccaccaaca ttaacatggc ggatctgatt
    24901 ccgttagcca gacagctggc gaatttccac atcggagata ccaagggctt cccgatggcc
    24961 agaggcgagg caaacgtcgg aaagaacggc gactgcgtta ttcctcagac tctcgtttcc
    25021 aacgtatctg agcttcacca gttcctgttt ggaacggaga attaccagcc gtcctccaag
    25081 gtgcagtcct acagcgccca tatttccgag gcgactggaa tgtacaagga aggaaaatcc
    25141 attgaccacg taccggtgga tcagggctta aatgctagct cctatgtaaa ggcaaaacag
    25201 aagcgggcag ctgagaaggc ggccgcagag cagagagcca aggaggaggc cgaagctgcc
    25261 gccaagaagg atgagaccaa ggaggcagat caggctgaga cccaggagga gaccaaggat
    25321 tacttcggaa actgggatga ggaagaatgg gacgaagagg actgggagga cttctgggac
    25381 ggtgaggact ggtatgagga ctggggcgac gatggaattc caagcgacgg aggagccaca
    25441 ggacctggag cagacacctc aggtccggca ggcggttctg gagatcaggg aaattcaaac
    25501 tctggagaaa acggatcttc caagcctgga agcggttcta aggctccgga gaaggagagc
    25561 agtccgtccg gaaacggaag cagctctgga aagactcctg gaagcggcga gagcaaaccg
    25621 gcttcagggg aaaataccaa agagagcgtt tccagtccgg aagcaaacag cccggtaagc
    25681 cagcccagcg ctccgtcatc cccgcagagc ggatccggag aacagggaaa aaacaaggag
    25741 ccgcaggctc ccaatacgtc caataccaat caggaggcag caggacctgg agacgccggt
    25801 cctgccggcc ctgctgctta acattccggc caacggatgg atggcagcag aatcaggtga
    25861 gatactatga taaaagataa tcagaaacgg ctgaaccgtt tccatgtagt gttagatgca
    25921 tttgtgatac tggcttccta ctggctggcc tggtttgtga tcatggttct gagccccaag
    25981 gctacggttc acaaccggca ggccatggca gaggtatata ttctggcagc tgtgatgatt
    26041 gtacctctgt atctgattct gtacgccttc tttcacctgt acacgcctaa gcgggtgcag
    26101 ggaagacgga cagagctggg aaatatcatc aaggccaata ccatcggtat tctggccatt
    26161 gcgctggtat tgttcctgaa cgccaagaac gactatgtca tcaacttctc acggtggatg
    26221 gtagtctgct tctatgtgtt taacattgtt ctggaattcc tggagagaaa tttaatccgg
    26281 cggacactcc gctccatgcg ctccaagggc tacaatcaga agcacattct tctggtaggc
    26341 tacagccggg ccgctgaggg ctttatcgac cgggtgagca tgaatccgga gtggggctat
    26401 caggttcggg gaattctcga cgatcatgag gaatggggaa aagagtacaa gggagtccgc
    26461 gtaattggaa agacaggaga gctggaggcg atcctggagc tgaacacgct ggacgagatt
    26521 gccattaccc tgggacttag agagtacgga aagctggaga aaatcgtggc tgcctgtgaa
    26581 aaatcaggcg ttcatacgaa atttattcca gattacaata acatgatccc cacgctcccc
    26641 tatatggagg atttgcaggg gcttcctgtg attcatatcc ggcacgttcc cctgaccagc
    26701 ctgaccaacg cgacgatgaa acgcatcatc gacatattcg gggcgctggt ggctattgtg
    26761 ctgttttccc cgattatgct ggggacagcc gcagcggtga agcttacctc caggggaccg
    26821 gtgattttca gccaggagcg ggtaggcctt cacaacaagc cgtttaagat gtataagttc
    26881 cgctccatgg aggtgcaggc gccgtcccag gagaagagca agtggacgac gccgggagat
    26941 ccgagagtga ctccggtggg aaaatttatc agaaagacaa gcattgacga gatgcctcag
    27001 tttttcaatg tgctgaaggg cgatatgagt ctggtcggcc caagaccaga gcggcccttt
    27061 ttcgtggaga agttcaagga agagattccg cggtacatgg taaagcacca ggtaaggccg
    27121 ggactcaccg gatgggccca ggtcaacgga taccggggag acacctcgat tgtaaagagg
    27181 atagaacacg atctgtacta tattgaaaac tggacattgg gatttgactt taaaattctg
    27241 tttctgacga tttttaaggg atttatcaac aagaatgcgt actagaatga ggaagctaca
    27301 tgaggtatga ggatgaaata gaccgttcca ggcgccggca gagccggggc agggagacag
    27361 tcaagcgttc gggcaacaga aacccggcgc cgaaccggca gaaggagctg acgctgatca
    27421 cggattcctt taaggaggat gcgaggcggc ggaacggaag gacagagggg gcctatggag
    27481 gacctcaaaa gtcttcttcc agaaagaaaa cttcgaaaaa agaagagaaa aacaggaagg
    27541 cagctgccca ggggcataat cagtcctacc gggcgtcagc caaaaagaag gcgaaaaaga
    27601 agagaagaag gattgccctg atcgctctct ggattgtgct tcttcttgga acagctgttt
    27661 ttgcaggcta caaatatctt gatattaaat ggaaggggct gactcagcgg gatgaaaact
    27721 ggaatccgga cgatctgatc aacctggaaa tttcagagga aaagcaggag cagatggagg
    27781 gctactggac cattgccgtg ttcggactgg acagccggaa cggctccgta ggcaagggaa
    27841 ataattccga cgtcaatatt atctgcaacc tgaactgggc cacaggagag atacggatgg
    27901 cttccattta ccgcgatacg tatctgaacg tcagcgataa gaacagctac aataagatca
    27961 attccgcctt tttgcagggc gggccgacgc aggcggtaaa ggctctgaat aaaaatctgg
    28021 atttggaaat cgacgattac gccgtattta actggaaagc ggtggcggag gccatcaaca
    28081 ttctgggcgg agtggacatt gagattacaa aaaaggaatt ttactatatc aacgccttta
    28141 ttacagagac ggtaaaggcc acgggaattc cgtccacaca gctgaaaaag gccggcatga
    28201 accatctgga tggcgtccag gcggtggcct acggccgtct gaggcttatg gacacggact
    28261 atgagagaac agccagacag aggaaggtca tttccctggc ctttgagaag gcgaaaaagg
    28321 cggattgggc taccctcaac aacgtgattc agacgcttct ggtgacagaa caggatgtgg
    28381 acaccagcat tgacttagac gatattgtga agatggcgcg cggtattaca aagctccaca
    28441 tgggagagtc ctatggcttc ccagaggaca gaaaggaagg ccgggtaggc agcaagggag
    28501 actgcgtcat tccaaatact ctggagagca acgtggtgaa gcttcacagc ttcctgttcg
    28561 gggacgagaa ttatgagccg tcctcacagg taaagaacat cagcaataag attgcctctg
    28621 actgtggagc cgggggaaag aaggaaacgc cgaaggccac gaaggctccg gagacagagg
    28681 cgctctccac cgaggacctg aacagtacgg aagcgacagg ttcccatgga gaaacctctc
    28741 caagccatga atactggtat ccgtgggagt ctgagacaga cgacggggcc acgggaccgg
    28801 gaaaggctac aagaccttac gagactggaa gcagtccgta tccgggagaa acgcatccag
    28861 gcggagaatc aaggccggcc ggggagcagc gtccgggagg cgggacacag gcgcctcagg
    28921 agagcgagag cagtcctgga tccggcccga cacagatgcc tcaggagagc agctcaggca
    28981 tcatcattta ccctgaggga ggggagaacc agaacggagt tcagaagccg ggaacagagc
    29041 agccgaatgc gccgggaacg tctggcggcc agaacggttc ccagaatact ccaggccaga
    29101 tcgcgcctgg cgggggaggc cctgaaaatc agactccggg ccagtataca gatacgggag
    29161 tgattttaaa tcccggttca gtaaacggcg gacagccggg acaatagaca gaagcggtgc
    29221 gctgcaggaa attttatcct gcagcgcatt ttttacttga ccttatacct ggtataagga
    29281 gtatgataca ggcaagagga aaggcgttcg cttccgttga cggcgggaac cgccgcctgg
    29341 cagaacaaga aaaatctggg cctgggctgg ctggaaggga ggagcatatg ggaaacatga
    29401 acattaagga ggcggaggaa gagactggca tcaccagaca gaatatccgt ttttacgaga
    29461 agaaggggct gattcagccg gagaggaata aggaaaatga ctaccggcag tattcagagg
    29521 aggatattaa gaggctgaag acaatcaaaa tgctgagaaa actggacttt ccggtggagg
    29581 atattaagga ggtgctggag gggaatacag actttactca ggctgtgaga aatcacctgg
    29641 acagcctgaa ggagagaaag aaggaattgt cggctcagat taacttttta gagaaaatgg
    29701 agcgggaggg ggcggatctg tccaatcagg aacggtacct gaggcagatg gagcaggagg
    29761 agcgccaggg aagacgcttt accgatattt tagaggatta taagagaacg gccagggagg
    29821 agagcagaag aagattcagc tttgtgccgg atactatggc caggactccc agagaattta
    29881 cagaagagct gcttcgcttt gcagatcagg agaagctgaa cctggtgatt accagagaag
    29941 gaatgaaccc gctgtttgag atagacgggg tttcctatga ggcgtttcgc ctgtcggggc
    30001 ggtttggcat tgtggttcag tgccagatga cagaacccag aaagcaggaa accgatttgg
    30061 cgcaacaggg agaggaggag aaacagaaga aggacagcgc aggaaaaaag gctgcgcggc
    30121 tgcttcacta cagctggccg gttcttatat gggctgtttt attcttttcc agagctggat
    30181 tcagctggtg gagcctattg atttttattg gaacctcggc ggctctgggg tgcggctgct
    30241 tcacatactg gaacctgaaa aactgacgga gggggatacg aggaaaaatt ttcttgttcc
    30301 acctaaagtc accgaaaatt tttcctcata tacagcagat gaaggggctg gagggtaacc
    30361 ggaaaaaatc atgtttgata aggaggaacc gcgatgttaa atatgtttaa gaagtcattt
    30421 tggatcccat atgaggacag tacagtgtat ccgactatgg caaaggctat ggaggaaatt
    30481 tcaaggtact gtgaggagcg tggtgaaacc tgtgttttca caggagacga tgaggtggaa
    30541 atcgaaggaa aaagatacga aatttacaga ggatatgaaa acggaagcag aggtaattat
    30601 ggaatcaagt gccgggagaa atagagggaa gcatgacgaa tctgccgcag aaaccgggct
    30661 tctcaggcct cctgattttc ccgcctcccc ctttacagaa taacgattga ttgatagaat
    30721 agtgaaacaa gcgaagcgtc aggactcccc atccgggaaa ttctggcgct taaagccgtg
    30781 tgaagaaaga cagaatggat aaggagaacg atacgtatgt atattatagc aggactggga
    30841 aatccaggag agaagtatga caacacccgc cacaacgcag gatttttgac catagatgcg
    30901 ctggcgtcca aatacaatat cgacgtgaag gagaaggccc acaaggccct gattggaaag
    30961 ggagtcatcg aggggcagaa ggtgatttta gccaagcctc agacctacat gaatgtgagc
    31021 ggagagagca tccgcgccct ggtagactac tacaaaattg cccaggagga actgattatt
    31081 attttcgacg acatcagcct ggaaccagga cagtttcgaa tccgcaagaa gggaagcgca
    31141 ggcggccaca atggaattaa aagcattatc gctcacctgg gaacccagga gtttacaaga
    31201 atcaaggtag gcgtaggaga gaagccgccg aagatggatc tggcagacta tgtgttaggc
    31261 cgctttttga aggaagagca ggataccatg aagcaggctt ttgagaatgc ggcaggagcg
    31321 gcggcggcca ttgtcaccca gggggcggac gcggccatga acctctataa cggttccaag
    31381 aaaaaatccg agaagaagac agaaaagcca gaagaaaaga aatcagagga aaagaaggca
    31441 gaggagaaaa cggcggaagg aaagaagcct gaggttcaga cgccgggaac aggagcctcg
    31501 tctgcttcat aagccgggca ggcaggaagg cagagaacag aaaaaagaga cctagaaaga
    31561 acaggacaaa gaaaggacag gagggagaca gatgggaacc atatttgcca atccgctgga
    31621 ggagctggct gaatttcagg atatgaataa agagctgaac gaggggcggg ggcctctcca
    31681 ggtcagcggg tgcgtggact cgcagaaggc tcacctgatc agcgagacag gaggcgggaa
    31741 aaggtggaag ctgattgtca catacgatga ttccagagcc agggagctgt ttgaggacta
    31801 cagaaccttc gatccggctg tgtatctcta tccggccaga gacctgctgt tctacagctc
    31861 cgatattcat ggaaatcttc tgacccgcca gagaatgcag gtatttaaaa gcctccttga
    31921 aaatgagaca ggaacagtgg tgactacggc ggatgccctg atggatcgtc tgcttcctct
    31981 gcctgaaata cagaacagct gcgttcacgt ggcctgcgga gagacaattc ttctggagaa
    32041 gctgaaggga aggctttccc agctgggtta tgagagagtg ggccaggtgg acggcatggg
    32101 gcagttttcc atccgcggag gaatcatcga cattttccct ctgacagagg agctgcctgt
    32161 ccgaatcgag ctgtggggcg acgaggtgga ctccatccgg agctttgacc tggaaagcca
    32221 gagatcggtg gaagagcttc aggaagtcgc cctctaccca gctacagagc ttctgcttct
    32281 gccggagcgg atggaggaag gcctgaggca gattgagaag gagaccaagg cctatgccag
    32341 ggcgctgcgg gaacagatga aaaccgagca ggcggccagg atagaaggat cggtgagaga
    32401 gctttccgag gagattaagg aaggcttccg ggttcacggg ctgggcggtt ttatccaata
    32461 tttttccgag accacggttt cctttctgaa ttattttccc aaagatcatc tggcggtttt
    32521 tctagatgag ccgcttagaa tcaaggaaaa ggccgaggtg gtagagacgg agttcagaga
    32581 gagcatggcc caccgcctgg agggaggcta tctgcttccc gggcagacgg attttctcta
    32641 ttctgccaag gctctgctgg ctatgacagc cctgccctgt actctgcttc tctcaggcct
    32701 tgaccagaag ctttcaggct ttccggtaaa gaaaaagtac agcattgagg ccaagagcat
    32761 gggaacctat cacaatggct ttgagctctt aatcaaggat ttggagcggt ggcagaaagg
    32821 aaaatacagg gtagctttac tgacggcttc ccgaaccagg gccagccgtc tggcaaatga
    32881 tctgagagag tatggcctga aggcctacct gccggatcag gactgcagcc aggtgaaggc
    32941 cggagagatt atggttacct atggaaatct ccacagaggc ttcgagtatc cgctgcttaa
    33001 atttgccgtt gtcacagaag gagacatgtt tggaaacggc cagggcaaaa agaggaaaaa
    33061 gaagaagacg tcctaccagg gcaggcatat ccagagcttt tccgagctgt ctccgggaga
    33121 ttatgtggtt catgaaaacc acggtcttgg catttaccgt ggaattgaaa agattgagca
    33181 ggacaaggta gtcaaggact acattaaaat cgagtatgcg gacgggggca atctgtacct
    33241 gccggccaca aagctggagg ggatccagaa atatgccggc gcggaggcga aaaagcccaa
    33301 gctaaaccgc ctggggggaa gcgagtggca caagaccaag acgagagtca ggggagcggt
    33361 cagggagatt gccaaggatc tggtgaagct gtacgcggcc cggcaggatc aggaaggatt
    33421 tcagtacggg ccagatacgg tgtggcagcg ggaatttgaa gaaatattcc cctacgagga
    33481 gacggaggat cagctggacg ccatcgacgc ggtaaagcgg gacatggaga gccggaagat
    33541 catggaccgc ctgatctgcg gggatgtagg ctacggaaag acggagattg ccctgcgggc
    33601 ggcgtttaag gccatccagg agggaaagca ggtagtatat ctggtaccca ctacgatttt
    33661 agcccagcag cattacaata cctttgtcca gagaatgaag gattttccag tgcgggtgga
    33721 tatgatgtcc cggttccgca cccccgccga gcagaaaaaa acgctggaag atttgaaaaa
    33781 gggtctggtg gacgtgctca tcggaactca ccgggtgctg tcaaaggatg tggaatttaa
    33841 aagcctggga cttttaatta tcgacgagga gcagcggttt ggcgtggccc acaaggagaa
    33901 gatcaagcag ctgaaggaaa atgtggacgt cattaccctg acagctaccc cgattcccag
    33961 aacgcttcac atgagcctta taggaatccg cgatatgagc gtgctggagg aacctccggt
    34021 ggaccgcctt cccatccaga cctatgtgat ggagtacaac gacgagatgg taagagaggc
    34081 catcagccgc gaggtggcca gagggggaca ggtgtattat gtatacaacc gtgtcaacaa
    34141 cattgaggag attgccggcc atgtggcggc tctcgttccg gacgcctctg ttaccttcgc
    34201 ccacggccag atgcgggagc acgagctgga acggattatg ctggactttg taaatggaga
    34261 gattgacgtt ctggtttcca ctaccatcat tgagacgggc ttaaatatcc ccaatgccaa
    34321 cacgattatc attcacgacg cggatcggct gggcctgtct cagctttacc agatccgggg
    34381 acgcgtgggg cgctctaacc ggaccgctta cgcctttctg atgtatcgga gagataagct
    34441 cctcagggag gaggcggaaa agcgccttca ggcaatccgg gaatttacgg agcttggaag
    34501 cggaatcaag attgccatgc gggatctgga gatccggggc gcaggcaata ttttgggggc
    34561 agagcagcac ggccatatgg aggcggtagg ctacgattta tactgcaagc tgttaaatga
    34621 ggcagtgctg gccttaaagg gagagacgga tgaaagccag gagtttgaaa cctccgtgga
    34681 ctgcgacatc gacgcctata ttccgccctc ttatattaaa aatgaatatc agaagctgga
    34741 tatttacaag agaatttccg ccatcgagtc ggaggaggag tacatggata tgcaggacga
    34801 gctgattgac cggttcggag agcttcctgc tccggtggaa aatctgcttt tgattgcctc
    34861 tgtgaaggcc ctggctcaca gcgccggggt gacggaggtg aatatcaacc ggcaggaggc
    34921 cagaattacc atgttcaggc aggctagaat cgacgtgaca ggcattccag agctgatcag
    34981 ccgctatcgg ggcgatttaa agctgcggcc gggcgatgcg ccggaattta tgtacctgga
    35041 tcagcggaat aaaaataagg actgccagcg gatgatagaa aagacgcagg aaattctgag
    35101 aggcctgaag gagcttagcg ggcgcagcca ggacgcaggc aggaaataag gaacaggaaa
    35161 gaggcaggac gcgcaggcag aagacgggat tccgggagaa tccctctgcg ctgaaaacaa
    35221 tggaaaacga gaacagacag gggagaactg cagacgtgga gagtaaaaaa caggaaataa
    35281 aaagcgggac agagggagtg cgcctgaata agtttttaag cgaatcgggt ttctgttccc
    35341 gccgtgaggc agacaggctg attgaggcgg gaaaggtaaa ggtggacggg atgaccgctt
    35401 ccatgggcca gaaggtggag ccgagccaga aggtggaggc agacggaacg gtgatttccg
    35461 gaaaggacag gccggtggtg cttctggtta ataagcccag gggcattgtc tgcaccacct
    35521 cggacaagga tcgggcggaa aatattgtgg aatttctgaa ttatccggta agagtttacc
    35581 cggtgggaag acttgacaag gattcagagg gactgcttct catgacaaac cagggagagc
    35641 tggtcaatca gattttaaag ggcaggtacg ggcacgaaaa agaatacctg gttactgtta
    35701 ataaggagat tacggcgtcg tttttagagc gcatgagaaa gggagtaaag attctcgaca
    35761 ctgtgacaag gccctgtacg gcagagcaga caggcgagaa atccttccgc attattttaa
    35821 cccagggctt aaaccgccag atccgccgga tgtgtgaggc gctgggatac cgggtaaaaa
    35881 ccttaaaacg ggtgcggatc atgaatctgg agctgggatc cttaaagaca ggggagtacc
    35941 gggagattac gaaagaggag taccgggagc tgaaacgcct gttagagggg cgcgcaggcc
    36001 gcgggaatct ataaaataaa ataaaaatct ccccggaagc gtttttgcat tccggggaga
    36061 aatgagatgt ttctgaaggc gtttttctca gccgcttcct agaggaagaa ctccggctct
    36121 gcccgtctgg tatagttctg ttccagcatg gccacatggg ataaaaatgc cggatcgtcg
    36181 aaatacttgg ctccggcagg gcattttttc acacaggcct ggcatttaat gcagatgccg
    36241 gacaccaggg acggatcagc cgcgtcgatg gatcccatag gacaggcctt cacgcagatg
    36301 ccgcagctgt cgcagagctc tgcttttgta aggggctttg cctttaagaa tacggccggc
    36361 tttccgtctg tgccgagagg ggtgtagtaa gggcctaccg gatcgtcgcc tctcacggag
    36421 acaggagcag ggatttctgt cagattcatc accttttcgg ctgcagagac ggcaaatttc
    36481 tcaatggccg cccagtccgc ctcatcagga cgtccgggag ccagcttttc agaaaagacg
    36541 tggcggcagg cgattccagc gcctgcgact gtgtggaagc cgttgttttc cagctcattg
    36601 cgaagctcga taaggccgtt gtcaaaattt ctgtttccaa aggtgacaac cggcacagcc
    36661 agagcgccgt ctgccttaaa gcagttctga acggcaggca ggagcttatt gggaacgcgt
    36721 ccggcgtata cggaggttcc gaacacaacc agatcggaag ggccgtagtt ctgagttttc
    36781 gtccggctgt caggaagcgt gtagtcatag gaatcggtgg gaacgcccag cttttctgca
    36841 atgaggccgg caattttttc tgtcaccgcc ttggtgcttc ccacagcgct gtagtagaca
    36901 gctgtaactt ttgtgatttt cataatcaat ttctcctctc ataggggtgg attagcgtct
    36961 gacgcctggg gcccgctgct ttggccctgc ggacgtccat attcagacgc cggttttgca
    37021 ggcgctaggc ctgccactga ttgtagctga taatttcgtc cagagatttg cgggtttttc
    37081 ttctgggggc gtcggacaga gccgggtatc ccacggcgat caccagcctg gccgggcagt
    37141 gttcagggac gttcagcagc tggcgggcct tctcctggtt aatggttcca agcatacagg
    37201 tgccaagccc cagagaggaa gcctcgcagc acagagacat ggcggccatt ccaatatcca
    37261 tctgggcaaa gtgctgggat ccgtactggg cctccacagc tggttttaag tgggctgtct
    37321 cctcgcagat gacgataaag gcgggaacac gatccgccca gggacagccg cagactcccc
    37381 ggtcgtccag aacttccccc atccggcctt tcacttccgg atcgtccact acaatgaaac
    37441 gccatggctg agagttgcag gcactgggag agagaccggc cacctctacc agatgggtga
    37501 gaagttctct ggagaccggc ttgtcactgt agacacggca gctttcgcgg gtgcgctgaa
    37561 gtgcttcaaa atcttcaaaa tgcatagaac atcctcctgt tttgattcac atgtttaaag
    37621 atattgcttc taatgatatt atacaacagg ttttaaaaag agacaaacgg caatcgcagg
    37681 cgtctacggc agatccacca atgtaaaatc gtgctccaca gccggaagaa atttctctaa
    37741 aatatcagag gttttaattt tcaggctgga ggtgttgacg cagggatgac agcccaggaa
    37801 gggatcctcg agaagctctc tgtcaatagc cagcttcaca cgatgttctt tgtcgttcat
    37861 cagtcccaga acactgacag agcctgggga gatggagaga aacgcttcca tgtgggctgc
    37921 gtctgcgaac gataaacggg aacagcccat ctgcttcgaa aagacagagg tcctgaactt
    37981 cttatccccc ggaagcagaa ggagataaaa ggcagaggcc tgagcgttgc acagaaataa
    38041 atttttgcac atattcacct gaagcgcctg gtcaatatcc cggcaggctt caatggtatc
    38101 ggcctgtggg tggtcagccc tctcgtaagg gatggagagc ttatccaaaa aatcatagac
    38161 ctgaatttca cggggcagac ggccctcctc agagacaggg cgtccggaat agactgcgat
    38221 atttgaagcg gcagtgtctg tattcatatc ggtaaaatcc tcctttataa gctattataa
    38281 agggaaaagg gaaaattgca agaatagcgt cagtgtacac taatgctatg tccgacttga
    38341 aacagctgac ttgaaaccgt ccggcttttc attgcgcccg gcagccagat ggactataat
    38401 agccgaaacg gcacaggaac tgaacggaaa taaaaaacag gaatacagaa atagtttaaa
    38461 acggcaaaat aattaagaac aatacaatca cacaaaggga ggaagagaac agagatggca
    38521 gacagaagca aaagaacaga gacagccgga aaaagggaga agctggtaaa gcaggaaagg
    38581 aagaacaggg agcagccaag gagagaaaaa ggaaaagcac gggagactgg aaaaacagga
    38641 gaagcgtgcc ctgtttataa aaagtgcggc gcctgccagt acctccatct ttcctatgag
    38701 aaacagctgg ctaagaagcg ggagatgctg gaaacgcttc tggctggaag ctgtccggtt
    38761 aaagagatga tcagaatgga gcagccttac cattacagaa ataaggtcca tgccgtattt
    38821 ggccatgacc gccggggcaa cgccgtttcc ggcgtttata aagagggaac ccacgacctg
    38881 attcccattg aaacctgtct gattgaggac gagaaggccg acgagatcat cggaaccatc
    38941 cgttccatgc tccgctcctt taagatcaga accttcgacg aggacacagg ctacggactg
    39001 ctccgccatg tgctggtgaa aagaggcttt gccacaggag agattatggt ggttctggtg
    39061 actgcatcgc cggtatttcc gtcgaaaaat aattttgtta aggcgctgag agaaaagcat
    39121 ccggaaatta cgacgattat ccagaatatc aatggaagaa gtaccagcat ggtgctggga
    39181 gaaaaagagc acgtgctctt tggaaagggg tatatcgagg acgttctgtg cggccaccgg
    39241 ttcagaattt cttccaaatc cttctatcag gtgaacccgg tgcagacgga gaagctttac
    39301 aataaggcca tggaattagc cgctctcacg ggaagcgaga cggtgttaga cgcttactgc
    39361 ggaatcggaa ccattggaat cactgccagc ggcagagcaa aacgggtgat tggagtggag
    39421 cttaataagg acgccgtcag ggacgccgtg cagaacgcaa agagaaatga gataaaaaac
    39481 atcgagttct actgcaacga cgcgggccgt tttatgagca gaatggccgc ccagggcgag
    39541 aagctggacg tggtgtttat ggatccgccg cgaagcggca gcacagagga atttattcac
    39601 tctgtagcag aggcaggccc caggaaggtc gtttacattt cctgcggccc ggagaccctg
    39661 gcaagggatc tgaaaatatt tgccaggaac ggataccggg cacgggaagc ctggggagtg
    39721 gatctgtttc cgtggacggg acatgtggag acggtagttc ttttgtccag aaaaactccg
    39781 gatgatacga tagaggtcga cttagacttg gatgagcttg atattaccgc tgctgagtca
    39841 aaggctacct atcaggaaat caaggattat gtgctgaaag aatttggctt aaaggtttca
    39901 actttatata tttcccaaat taaacgcaaa tgtggtattg atgtaggaga acattacaat
    39961 atttcacaga aagaaaatca gaaagtacca caatgcccga aagaaaagga agatgctatc
    40021 cgagctgctc ttgaacattt tgcgatgatc taaaggtcat tgctgatttc aaggaggaat
    40081 agcatatgaa gtcattattc gaagaaatgg gcggtacata tacgctcgga gcagatggaa
    40141 tgtattatcc ggatttggaa cttccggagg aagaaccgca ttacggaaag tacggcagaa
    40201 tgcgtctgcg ctatctgaaa gaacaccata agatgctgta caacacactt ttgctggatg
    40261 gagaactggt caaacatctg aatgaggtgg atgataccgc taatcaaaga atggaactgt
    40321 tgaccctgca aatgcaggag cagcagggca taaacgaagc attaaaggct cgtgatcaga
    40381 tggcatgggt tggtgcttgc aataacatcc gaaatgcggc agaggaaatt gttttgaatg
    40441 aattgatatg ttgttaaatc gagaaggagg gagtgatgaa ttccctcctt ctcgattctg
    40501 aagatatcat ctcttttgga gaatgaaaag ggattttgta gaaaaattta tgcttatata
    40561 ctaaaatgca cataaggaaa tacaaagctc tacaaattat ttatttatgt gtaacgaatg
    40621 atga
//
LOCUS       DBMDUW010000022        37968 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_900_length_37968_cov_3.479098, whole genome shotgun sequence.
ACCESSION   DBMDUW010000022 DBMDUW010000000
VERSION     DBMDUW010000022.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 37968)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 37968)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37968
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_900_length_37968_cov_3.479098"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(182..2278)
                     /locus_tag="ACZPCR_06000"
     CDS             complement(182..2278)
                     /locus_tag="ACZPCR_06000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HIR1230463.1"
                     /translation="MNVYGTKQIRNVVLLGHGGAGKTTAAEAMALVTGVTKRMGKIAD
                     GSTISDYDKEEVKRQISISTSLVPLEYNGENGPIKINLLDTPGYFDFVGEVEEAMSVA
                     DAAIIVVNCKAGIEVGTEKAWELCEEYRLPRLIFVTNMDDDQASFRELILKLEKRFGR
                     KIAPFQVPIRENEKFVGFVNVVKMGGRRFTNLSDYEECEIPEYTKKNLNIVRDALIEA
                     VAETSEEYMERYFSGEEFTQEEISAALREHVTEGNIVPVLMGSGVNAQGFSHLLQAID
                     KYFPSPDKFECVGVDVSTGERFTAKYNDDVSLSARVFKTVVDPFIGKYSLMKICTGTL
                     KPDSVIYNVNKDAEEKVQKIYVLRGKEAIEVPELKAGDIGAVAKLTVTQTGDTMAVRT
                     APIVYHKPKISTPYTYMAYAAKTKGDEDKISTALSKLMEEDLTLRTVSDVENRQSLIY
                     GIGDQQLEVVVSKLLARYKVDMVLSKPKFAFRETLRKKVEVQGKYKKQSGGHGQYGDV
                     KMEFEPSGDLEKPYVFEERVFGGAVPRNYFPAVEKGIQECVLKGPLAGYPVVGLKATL
                     VDGSYHPVDSSELAFKMAATMAFKKGFMDANPVLLEPIASLKVTVPDKFTGDVMGDLN
                     RRRGRVLGMNSDHHGKQVIEADIPVSELYGYNTDLRSMTGGIGVYSYEFSRYEQAPGD
                     VQKREVEARAAEAEKD"
     gene            2647..3750
                     /locus_tag="ACZPCR_06005"
     CDS             2647..3750
                     /locus_tag="ACZPCR_06005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008977 - prephenate dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0033730 - arogenate dehydrogenase (NADP+)
                     activity [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA];
                     GO_process: GO:0006571 - L-tyrosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase/arogenate dehydrogenase
                     family protein"
                     /protein_id="HIR1230464.1"
                     /translation="MQTQHLTAGFIGLGLIGGSIARALKKQAPSTTVMAYMRSRDRLL
                     KAQEDGAVDIILEGVGEPLRQCDIIFLCTPVEYNASYLEQIRPYLKPGAVITDVGSTK
                     TQIHEAVQSLAMEESFIGGHPMAGSEKTGYENSTDHLLENAYYILTPTDKTPESSVAM
                     MTQTASLIGAIPLVLDYREHDRIVAAVSHLPHIIASSLVNLVRDKDGSQGLMKRLAAG
                     GFKDITRIASASPVMWEQICMTNETNIASLLRDYIESLNRILTVLDSRDSDSVRELFE
                     SSRDYRNSFETRVSGPIAPDYSFSVDVCDEPGAISIISAILAGKGISIKNIGINHNRE
                     NGEGALSINFYDEKSRNAAWERLKKYNYTLFNF"
     gene            3769..5049
                     /gene="aroA"
                     /locus_tag="ACZPCR_06010"
     CDS             3769..5049
                     /gene="aroA"
                     /locus_tag="ACZPCR_06010"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008398801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HIR1230465.1"
                     /translation="MIFSTNKGGLRGELTVPGDKSISHRSVMFGAISRGLTEIDGFLQ
                     GADCLSTIACFQHMGVSIENRGNRVLVHGNGMRGLKQPDGVLDCGNSGTTTRLLSGLL
                     SAQPFSVTLTGDESIQKRPMNRIITPLSQMGASIQSMGGNGCAPLRIEGRKLHGISYQ
                     SPVASAQVKSSILLAGLYADGETRVTEPYLSRNHSELMLSHFGADVRTEGTTAILKPA
                     EELFGQRITVPGDISSAAFFIAAALILPGSELLIKNVGVNPTRDGILTVCRQMGADIT
                     LLNPSSESGEPTADLLVRHSALHGTVIEGAVIPTLIDELPMIAAMACFADGETVIKDA
                     AELKVKESNRIAVMTDSLKAMGADVEETEDGMIIRGGKPLHGAVIDSRKDHRIAMTFA
                     VTALASSGETEILDADCVNISYPSFYEDLKRLQA"
     gene            5068..5838
                     /locus_tag="ACZPCR_06015"
     CDS             5068..5838
                     /locus_tag="ACZPCR_06015"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230466.1"
                     /translation="MMLHKNKKIVLVLLSLALLAAALLAVSFRASSVSFSSGEICSDL
                     SSQESFSFLKTYYYEHQNGEIEENTIRNTYRALPSEAIETCFFDPVTGETSPPQYYAK
                     DNESWFFYRYEKDDTWSREKLENFTVKDYLMTSSFSISGVDLQIVKDWKQAGTETLHE
                     RQSVRFDGTCSMEQYLKEKARLSGEAYIEPSADPGGLGTIRVSVWVDKTSHEALQLQY
                     AFPAPAQPGKSGGTDVITVTLWDETDPFEIPEAAEVSD"
     misc_binding    6104..6348
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6458..7546
                     /locus_tag="ACZPCR_06020"
     CDS             6458..7546
                     /locus_tag="ACZPCR_06020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIR1230467.1"
                     /translation="MRKKTIAALVTAVMAVSALTGCSSSEGARETGNTSSEAGSSAAE
                     SSRSGEAQNSEAAEGEYTIGVAQYAVHGSLDNCREGFLKGLAEEGFVEGKNLEVIYEN
                     ANGDGSLSGQIITNFVSNDVDMVCAIATPIAQSAYSVTKRSDIPVIYTAVTDPVLAEL
                     ATEDQMPVGNITGTSDKLPVSEQLSMIREILPEAKTVGILYSTNEVNSQAAIEEYKKA
                     APEFGLEIVESGISTSADIPLAAEQLAAKVDCISNLTDNNVVSSLPVVLEAASKNGIP
                     VFGSEIEQVKRGCLATMGLDYIALGEQTGRMAAQVLKGEKEASEMPYELIEGAAFYGN
                     TEAAENLGIELPESLTSSAAELFEEISE"
     gene            7577..8467
                     /locus_tag="ACZPCR_06025"
     CDS             7577..8467
                     /locus_tag="ACZPCR_06025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009244174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1230468.1"
                     /translation="MSILLSILTQGLIYSLMALGVYITYSILDFPDLSVDSTFPFGAA
                     VTAAAIVAGVPAPLTLPLSFAAGALAGTATGLIHVKLKIRDLLSGIIVMTGLYSINLM
                     IAGNKANLPIYSQETIFENEMTASLSSRSYELTVAAILLILVVFVKIVMDLYLKTRSG
                     LLLRAAGDNETLVTALAKDKGTVKIIGLALANGLAALSGCVFCQQQGFFDIGVGTGTI
                     VTGLASVIIGTKLFAKLGFLKTTTAVILGSVLYKACTSMAMSIAQNFGINTSNNKFVT
                     AAMFLIILVLSGRSFRKKVD"
     gene            8467..9240
                     /locus_tag="ACZPCR_06030"
     CDS             8467..9240
                     /locus_tag="ACZPCR_06030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1230469.1"
                     /translation="MLEVKHIRKYYNQGTVNEMCLFEDFSLTVEQGQFVSVVGSNGSG
                     KTSLLNIICGSIPVDSGSILIHGTDISKMPEYRRQRVIGRVYQNPSMGTCPNMTILEN
                     MSLADTKGKPFNLRRGTNKKRIDFYRENLRLLGLGLEDKLDVKAGVLSGGQRQAMALL
                     MSTMTPIEFLILDEHTAALDPKTAEVIMELTDRIIREKKLTALMVTHNLRYAVEYGNR
                     LLMMHQGQAVMDKAYEEKESVRVDDILGKFNEISIECGN"
     gene            9288..9707
                     /locus_tag="ACZPCR_06035"
     CDS             9288..9707
                     /locus_tag="ACZPCR_06035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008977422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PPC domain-containing DNA-binding protein"
                     /protein_id="HIR1230470.1"
                     /translation="MDYRRFGNTIAARIDKGEEILEQVKAIALKEEIKLASIQALGAV
                     NQFTVGVFKTDEKKYMANDFAGSFEIVSLTGTINTMDGEFYCHLHMSAGDDKGHVFGG
                     HLNRALVSATCEMIITVIDGTVDRAFSEEVGLNLFRF"
     gene            complement(9687..10628)
                     /locus_tag="ACZPCR_06040"
     CDS             complement(9687..10628)
                     /locus_tag="ACZPCR_06040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006442690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HIR1230471.1"
                     /translation="MELGNRGSKGGRLGRTRRLRLLCQAAWFALTNGYAAGFLEKKIY
                     TGKLKSLCVPGLNCYSCPGALAGCPIGSLQAVLSSSSFTVSCYVLGFLMMFGTLLGRF
                     ICGWLCPFGLVQDLLHKIPFPGKKKNLPGHRFLIYMKYVILVLFVILLPSLAVGVTGN
                     GNPWFCKYICPSGTLMAGLPLGLGNPMLRTALGKLFSWKVFLLVLTVVLSMKYYRPFC
                     KYVCPLGAIYGLFNPISLYRFRIEEKTCIQCGACQKVCKMDIRVWKTPNSPECIRCGD
                     CKSVCPTGSIRSTMERMRAEGSGKAEAYEKQLETEQV"
     gene            complement(10615..10776)
                     /locus_tag="ACZPCR_06045"
     CDS             complement(10615..10776)
                     /locus_tag="ACZPCR_06045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009444510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1871A family CXXC motif-containing protein"
                     /protein_id="HIR1230472.1"
                     /translation="MKCKTDRKKAFGPVQGGLLLTAAVLLAAGVYRGEAATVFIKAAN
                     ICLECIGIG"
     gene            complement(10802..11425)
                     /locus_tag="ACZPCR_06050"
     CDS             complement(10802..11425)
                     /locus_tag="ACZPCR_06050"
                     /inference="COORDINATES: protein motif:HMM:NF012787.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HIR1230473.1"
                     /translation="MKKRYRIALAACMTAAALTACQGKAAEPDASAAVSEKTGTGASE
                     TKEKKQGEKESSGVFESFTAQDLDGNQVDETIFEDAELTMINVWGTFCTPCLEEMPDL
                     AELNREYQEKGVQIIGICSDTINADKELDEAQLEKARELAEQTGADYPHIAMSGTLVD
                     TLLPQVMAVPMTIFVDSEGTQVGTAYMGARDKEGWAGILDEVLASVQ"
     gene            11643..12071
                     /locus_tag="ACZPCR_06055"
     CDS             11643..12071
                     /locus_tag="ACZPCR_06055"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin family protein"
                     /protein_id="HIR1230474.1"
                     /translation="MTQDIELLNQIHQNADMGRDSVRHVIQLSNDVQFLHALNSQLDE
                     YELAYEESGRMLRAHGAAAEDASPVAKAMARVSSTMKSLVNPTTSKLAEMVIQGNTMG
                     ATELKKQLNAYRGSNPSVVSLAQRQLKSEEKNIEDMKQYL"
     gene            complement(12133..12864)
                     /locus_tag="ACZPCR_06060"
     CDS             complement(12133..12864)
                     /locus_tag="ACZPCR_06060"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006776667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0017136 - histone deacetylase activity,
                     NAD-dependent [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family NAD-dependent protein deacylase"
                     /protein_id="HIR1230475.1"
                     /translation="MKEKIAVLKRMLDESNYTVALCGSGMLTDGGVRGIKNPDRAYAI
                     ERAYGASPEYIFTSAYYNTRPEQFFHFYKEEVLRYIPDPGLGSYAMARMEQAGKLQCV
                     ITANVFNQAIRGGCEHVINLHGTVYENQCPRCGELYTVEDILEMKGIPCCRVCNATIR
                     PKVSLFGEMVDSRIMTRTTEEIEKAEVLLLVGTTLRSETFSNYLKYFHGKYLAVLHRT
                     PHYSDEKADLTLIGEPGQILSQLGY"
     gene            complement(13060..13863)
                     /gene="hdhA"
                     /locus_tag="ACZPCR_06065"
     CDS             complement(13060..13863)
                     /gene="hdhA"
                     /locus_tag="ACZPCR_06065"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013658258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0016042 - lipid catabolic process [Evidence
                     IEA];
                     GO_process: GO:0030573 - bile acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="7alpha-hydroxysteroid dehydrogenase"
                     /protein_id="HIR1230476.1"
                     /translation="MNVKGKVVIVTASTRGIGWACVQAFVREGAIVYLAARNEEAAKK
                     RIEELSGEPGQAKWVYCDASVKESYTSMAETVEQAEGRIDVLVNNFGTSDPRTDLDIA
                     RTRYEDFLDTLDKNLSSVFLSTQAVLPAMRKQGGGSIVNISSIGGQIPDIARIGYAVS
                     KDAIIYLSKNIALQEGRNGIRVNVVCPGQTATDAVKNNMSDSFQELFLRHTPIRRMGT
                     PEEIAAAVLYFGSEEAAYTTGQVIAVSGGFGLGTPVYAELSQLSAEDRH"
     gene            complement(13860..15698)
                     /locus_tag="ACZPCR_06070"
     CDS             complement(13860..15698)
                     /locus_tag="ACZPCR_06070"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008398784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015833 - peptide transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HIR1230477.1"
                     /translation="MMRGDMGQDTEKRRKQEKILASVKDLSIEFTDRGIYEEVVKKIS
                     FPIYEGEILGVVGESGSGKSMSALSIMGLLPDSAQVKSGSIEFCKKDGNIVDLLQLSG
                     QEREKIQGEEIAMVFQEPMTSLNPVMKIGKQVGENLALHTDLSKEEIHEKCVKALQAV
                     GLSEAEALLDRYPHELSGGMRQRVMIAQAMIASPRLLIADEPTTALDVIVQAQILRLL
                     KKIHQENQTSILFISHDLNVIREICDRVLVVYQGVIVEQGDAEQVLNSPRHEYTKRLV
                     ASIPEKTGRADSQKEILKISHLDVFYREGGGFFKKASRKKALSDVSLSVREGEILGIV
                     GESGCGKSTLSKTIAGLNRDYSGTIETDGDLRPQMVFQDPFGSLNPAKKIGWILEEPL
                     RVRGVSDRAERKRMAEEMLVKIGLDESFYSRRPRELSGGQRQRISIGTALLADSRLLV
                     ADEPVSALDVTVQSQILKLLLDMHEERKNTLLFVSHDLNVVRRVCHRVAVLYLGEVVE
                     SGAVEEIYHNPCHPYTRLLLASSLGENSEKEKAERNDPGELVSDIGENFGRESAGCPF
                     YPRCPKRSGRCALSRPETMSLENGHKVKCFGCQAPSAEGRQKGEAI"
     gene            complement(15738..16538)
                     /locus_tag="ACZPCR_06075"
     CDS             complement(15738..16538)
                     /locus_tag="ACZPCR_06075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1230478.1"
                     /translation="MKKKRNWNLIIGLAITLFFLAGAVIGQFWTPYPPTQMDSLHVNL
                     APCLAHPMGTDNFGRDIFSRVMNGSGNTFFVAVCTVLIGGVIGTAAGALTGYYGGVLD
                     NVLMRVGDMIMSFPSVLLALIFISLLGPGKYNIILALGIIFIPVFARMVRSEVIRCRE
                     LDFVKSAKVMGVGNLRIIFIHILPNASVSILTTAAIAFNNAVLSEAGMSYLGLGVQPP
                     EPSLGRMLSEAQSFLFGAPWYAIFPGIVIILIILGFSMIGEGLRELQK"
     gene            complement(16554..17498)
                     /locus_tag="ACZPCR_06080"
     CDS             complement(16554..17498)
                     /locus_tag="ACZPCR_06080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1230479.1"
                     /translation="MKYFIKKLVTLIITLLLISLLTFTAFSVIPGDAALARLGDDATE
                     EQIEAFREEMGLNAPLPVRYVDWLSGAVRGDFGASYYYDNMTVGELLSDRLPVTVMLA
                     VISLLMILICSVPLGLLCARGAGGVLDHAVNQILQTVMAVPSFFLGILLTYAFGLVLH
                     WFQPGQFVEPSESFFGAASYLVFPALAVALPKIAMVVKFLRNAVLSELSKDYVRTAKS
                     RGNSSRRILYVHVLKNAMIPVITFTAMVVAEILAGSIIVEQVFSVPGVGRLLISSIFN
                     RDYPVVQAIVMYITLVVVAVNFLVDFMYQLLDPRVRTS"
     gene            complement(17560..19134)
                     /locus_tag="ACZPCR_06085"
     CDS             complement(17560..19134)
                     /locus_tag="ACZPCR_06085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012198462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIR1230480.1"
                     /translation="MMKKKKILLGLTALFVSAALCACSGGKNGEGTSAAAGDSTSAAE
                     TEGNTLSEGTPRPGGSVVVGMTQDLASLDPHATTDAGTRDVVFNLYEGLVKPAPDGSL
                     IPAVASDYQISEDAKIYTFTLRDGITFHDGAPVTAEDVKYSIDRCAEANQGSAFSMLS
                     EVTVKDEKTVEVTLTDSYSEFLSDLSQAYIIPASNADPAGTPIGTGPFRFVSYTPGQS
                     VVMEKYDGYWQENLPYLDQVTFKITADVDTAFMELQAGTIDILKYLNNTQVQTLGDQF
                     KIEEGSMNLVQGMFLNSSYEPLSKAEVRQALCYAVNRDEINQFMFGGKSRIIGTHMIP
                     NMSVYYEPETEKVYSYDPQKAKQLLADAGYADGFDLEITVPSAYSQHVDTAQIIVEEL
                     KQVGINASINQVEWSTWLSDVYKGGKFEATIVGFDGTLAPNDWLRKYVTGDSKNFMHY
                     SNAEYDETFQKAYTAVDEAEKAAFYKEAQMILAEDAASVYIQDPANFVAVNKEFAGYT
                     FYPTAGDDMSVVYQTN"
     gene            complement(19385..19546)
                     /gene="rd"
                     /locus_tag="ACZPCR_06090"
     CDS             complement(19385..19546)
                     /gene="rd"
                     /locus_tag="ACZPCR_06090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004845559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_process: GO:0072592 - oxygen metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rubredoxin"
                     /protein_id="HIR1230481.1"
                     /translation="MKKYICDVCGYIYDPAEGDPDNGVAAGTSFEDIPEDWLCPLCGV
                     GKDQFSVQE"
     gene            complement(19713..22835)
                     /locus_tag="ACZPCR_06095"
     CDS             complement(19713..22835)
                     /locus_tag="ACZPCR_06095"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006779285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HIR1230482.1"
                     /translation="MAVKDISVDTFWKGEVRVSGQVEDQGAVYQTKIYVKGSQIIDYS
                     CSCCRENSFRGVCSHGQELYQVYKDSESPEAARPVFTSSSARLMIREYTNRQVAQIVA
                     EEEKGEVEFIPRLLFSRREILMEAGLKKRREYQLKDLASFALAMREGRYVEYGRGLAF
                     NHDFQAFTEESRKTARLTAELAFSYLENYRQIRRGGMPAEPALRALRLSRGDLDRFFG
                     LNTGRAIRCEDARGQQRELTVVREDPDFAVLVKRAGKSGISVTVPSGMAAFEGEKRLY
                     VADEHHIFCCSTEYGNVMGIFLTGILGGQEEPGKLLIHERDVPLFYERVLSRMEPLGI
                     LSQEGVELENWRPEPLEAVFDFDCDEKGRLCLIPRLSYGDYSFHPLDDGDVPKSICRD
                     VPGEFRISRLITRYFAAREEGAGRLFLPEGEEAVYRLLDEGMEEFRSLGEIRLSGSVK
                     ALTIRRPPEISMGVSASDGWLTLTVDTGDLTGGELLKVLDAYTQKKKYYRLKNGEFLK
                     LSDDGFMTIETIREGLSLGKAELAKKTILLPSFRALYLDQALREDGHISLKRDSGYKA
                     LIRGMKSVEDSDYDVPSSFMGELKAYQKTGYRWLRTLDHWGFGGILADDMGLGKTIQV
                     IALLLSAAQEGTSLIVCPASLIYNWEHELYRFAPSLKTVTAAGTMSERRELLARMEEY
                     QVVITSYELLKRDQEWYEKQKFRFQIIDEAQCIKNAATKSAKAVKAVRARTRFALTGT
                     PVENHLGELWSIFDYLMPGFLFSYQKFRKLYEIPIVKEGNETAASNLRRLIGPFVLRR
                     LKKDVMKELPEKVEKIVYSAFSGEQKKLYGASVLRLKEEVESGEEKFKILSGLTRLRQ
                     ICCDPSLCYENYRGGSAKLDTCMDVIAGAVPAGHRILLFSQFSSMFPLMEKRLSESGI
                     DSFTLTGSTPKEERNRLAARFNAGEAQVFLISLKAGGTGLNLTGADFVILYDPWWNAA
                     AENQASDRAHRIGQRRQVTVVRLISKGTVEENILRLQESKRELADRIVTTGTVSLAGL
                     NREEILRLLE"
     gene            complement(22943..24712)
                     /gene="argS"
                     /locus_tag="ACZPCR_06100"
     CDS             complement(22943..24712)
                     /gene="argS"
                     /locus_tag="ACZPCR_06100"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002573535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HIR1230483.1"
                     /translation="MQKMIDLIVAELTPAFTACGYDEKYVKVTVSNRPDLCEYQCNGA
                     MAAAKAYKKKPIDIAGEVVEKAKESAMFSEINAVMPGFINLRIAPEYLAGYMNRMAED
                     PKYGLEETKEPETIIVDYGGANVAKPLHVGHLRSAVIGESIKRISRYMGHKVIGDVHL
                     GDWGLQMGLIIEELHDRQPNLPYFDENFTGEYPKEPPFTISELEEIYPAASAKSKQDE
                     AFKERAQEATFKLQSGYAPYRAIWEHIMNVSLKDLKRNYGNLNVSFDLWKGESDAQPY
                     IPQLIDDLVEKGLAYESQGALVVDIAEETDTKELPPCIVRKSDGAALYATSDLATIVQ
                     REQDYHPDRYIYVVDKRQELHFTQVFRVAKKAGIVSDKTKMVFLGFGTMNSKDGGPFK
                     TRDGGVMRLERLIADINEEVYKKVQEKQRVSEEEMRKTAEMIGLAALKYGDLSNQATK
                     DYVFDVDRFISFEGNTGPHIQYMVVRIKSILEKYRELMGGSYTLVPVRPASSETEKAL
                     QLELCRFGEVVETAFAETAPHRICQYMYDLSDAFNNFYLVNKIIGEEDREKQAGFISL
                     ISLTKDVLNACMDLLGIEAPEHM"
     gene            complement(24827..25597)
                     /locus_tag="ACZPCR_06105"
     CDS             complement(24827..25597)
                     /locus_tag="ACZPCR_06105"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008375036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0016019 - peptidoglycan immune receptor
                     activity [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0045087 - innate immune response [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein family
                     protein"
                     /protein_id="HIR1230484.1"
                     /translation="MGLYEEMREKNRRQRSGEALEEGRGRRRREPEAYERRKLKEGRR
                     LRRRRSRRTFLAAAALILFLSGGAAGWFLRGSLIREPVNPSSVETPEWVTQDLLTLND
                     YSRPGTKLSEINGIVVHYVGNPGTTARQNRNYFEGLKDQTGSNRISVSSNFIIGMDGE
                     IIQCVPIDEMAYASNTRNSDTVSIECCHPGKDGRFTEETYASLVRLTAWLCRELDLKP
                     KDVIRHYDITEKACPKYFVDHPDEWKEFLKDVKEAMKE"
     gene            complement(25802..26359)
                     /gene="efp"
                     /locus_tag="ACZPCR_06110"
     CDS             complement(25802..26359)
                     /gene="efp"
                     /locus_tag="ACZPCR_06110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008724890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HIR1230485.1"
                     /translation="MVSAGDFRNGITVEIEGNVFQIVEFQHVKPGKGAAFVRTKLKNI
                     KNGGVVEKTFRPTEKFPAARIDRVDMQYLYSDGDLFHFMNVENFEQVALTAEQIGDAL
                     KFVKENDMVKICSHNGEVFSVEAPLFAELEITETEPGLKGDTATGATKPATVETGAII
                     YVPLFVEIGDKVKIDTRTGEYLSRV"
     gene            complement(26426..27883)
                     /gene="aroE"
                     /locus_tag="ACZPCR_06115"
     CDS             complement(26426..27883)
                     /gene="aroE"
                     /locus_tag="ACZPCR_06115"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007863706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HIR1230486.1"
                     /translation="MTEREEMRKQPKDLERMIQAAESVRGTARVCGILANPVEHSMSP
                     MLQNLYAESTGTDLVYVPFKVKEEELQAAVSGAFALNILGMNVTVPHKQEVMKYLDDV
                     DEEAREVGAVNTLVRTERGYKGYNTDVEGLRRAVEEAGFAVNGRDCLLIGAGGAARAA
                     VCMMARGKAGSITVLNRSLEKAEELAEYGNRMAGRDLMKALPLSQWKELPGKRYLAIQ
                     CTSVGMHPAVDAAPIEDREFYQLIEEALDVIYTPAETKFMHLVREAGGRAVNGLKMLV
                     YQGAASYELWNPGTKIEKETLALAEALIQKRLQPEQKHLVLIGFMGAGKTSVGKDLAD
                     LLGCALCDTDQETERQAGMAVSEIFRLQGEESFRKMETDTLRRLLKQTDRDSGFTVIS
                     AGGGLVLREENQRLLKENAVCVYLKASPGQILHRLQGDTSRPLLQGGNVREKVEGLMV
                     ARGPVYEKAADITVNTDGRTPGEIAREIAAFAKSS"
     gene            complement(27890..28414)
                     /locus_tag="ACZPCR_06120"
     CDS             complement(27890..28414)
                     /locus_tag="ACZPCR_06120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006776380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HIR1230487.1"
                     /translation="MFRAFYPKEYRDSAYDIPYEDFYRQGIRGVIFDIDNTLVPHGAP
                     ADDRALQLFARLREMGMKTCLLSNNKEPRVASFAAQVDSPYIYKGGKPARGGYEKAMA
                     LMGTDRQTSLFVGDQLFTDVYGANRAGIYGILTKPIHPKEEIQIVLKRRLEAVVLYFY
                     RRDCRKREREAGKE"
     gene            complement(28416..28871)
                     /gene="nrdR"
                     /locus_tag="ACZPCR_06125"
     CDS             complement(28416..28871)
                     /gene="nrdR"
                     /locus_tag="ACZPCR_06125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008724885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HIR1230488.1"
                     /translation="MKCPFCNASDTKVIDSRPADDNSSIRRRRQCETCGKRFTTYEKL
                     ETMPLMVIKKDNSRELYDRSKIEAGILHSCHKRPVSPQQISETIDEIENQIFNKEERE
                     IETSAIGELVMDKLKDLDEVAYVRFASVYREFKDVGTFMEEIGKLLKKD"
     gene            complement(28940..29188)
                     /locus_tag="ACZPCR_06130"
     CDS             complement(28940..29188)
                     /locus_tag="ACZPCR_06130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HIR1230489.1"
                     /translation="MRLSEMKQKEVINIKDCSRLGFVGDVDIDICTGRVTALIIPGPG
                     CLWGFLGRESEYVIPWRDVKQIGDDIILVELCKKEQKG"
     gene            complement(29299..30300)
                     /locus_tag="ACZPCR_06135"
     CDS             complement(29299..30300)
                     /locus_tag="ACZPCR_06135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HIR1230490.1"
                     /translation="MRKKSLAAWAAAVLAVGALTGCSSQSTGDKAEETTKAEASQEAV
                     EESTQAEQTAFMEDADLVIAGGDPAGMAAAIQAVAEGTDPAKILVLGSSEKTLSGSCM
                     NASDTEEQSDAGIEDTVDSYIADTLAAGGGKGNEEMAEHLGEESRAALDWVRDLGVEL
                     SGVTQKEGSSAARSYEAAGGEELGSQIQTKLQEKFDSLNVTVAEDAELSKVLYGADGE
                     VTGVQVKDAGKEQELTCRSLIVTDSAYLDLLGELGVSYVTDESGKNTGLNVDSCANAV
                     TPDDGEIPGLYAAGDAIGTALHGDKALEGNELTGVVVFGTTAGTEASIYAQDNAPQQ"
     gene            complement(30489..31892)
                     /gene="pepV"
                     /locus_tag="ACZPCR_06140"
     CDS             complement(30489..31892)
                     /gene="pepV"
                     /locus_tag="ACZPCR_06140"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016805 - dipeptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HIR1230491.1"
                     /translation="MYREEIEKYIDSHRGEMLEDIKTLCRINSEKMPYQEGMPYGEGA
                     CRALETALSMAEGYGFSISNYDNYVGTVDFGGTESQLDILAHLDVVPAGEGWTVTKPF
                     EPVEQDGKLYGRGTADDKGPAVAALYAMRAVKELNIPLKKRVRLILGTDEECGSSDIA
                     HYYAVEKEAPMTFSPDGAFPVVNIEKGHLNCEFEAEFEPSQALPRVKSVTAGTKVNVV
                     PGKAYAVFEGLDDDMVREAGNQVEKETGVSFELVGKDGCLEITACGAGAHASTPQEGK
                     NAATALLLLITRLPFAACRQMEVIRSLTELIPHGDTEGKALGVAMADELSGALTLAFD
                     ILEITDSRMHGIFDSRTPICGNEDNVLKPVAEKMAEHGITVLTKEMLPPHHVDGNSPF
                     VKTLLGAYEEYTGRKGECVSMGGGTYVHDLKNGVAFGAALPETDNRMHGADEFAVIDE
                     LLLSAKIFAQVIADLCC"
     gene            complement(31957..32403)
                     /locus_tag="ACZPCR_06145"
     CDS             complement(31957..32403)
                     /locus_tag="ACZPCR_06145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HIR1230492.1"
                     /translation="MSKIDVVRKAMVEAMKAKDKARKDSLSMLLSALKNAEIDKREPL
                     TEEEENAIVKKEIKQTKETMETAPADREDIKSEAAARLAVYEEFAPADLTEEQIRQVI
                     AGVLAELGIEEPKKSDKGAIMKILMPKVKGKADGKAVNEILAGMLK"
     gene            complement(32429..34030)
                     /locus_tag="ACZPCR_06150"
     CDS             complement(32429..34030)
                     /locus_tag="ACZPCR_06150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HIR1230493.1"
                     /translation="MANTENTTEQIKKRRTFAIISHPDAGKTTLTEKFLLYGGAINLA
                     GTVKGRKATKHAVSDWMEIEKERGISVTSSVLQFNYEGYCINILDTPGHQDFSEDTYR
                     TLMAADSAVMVIDASKGVEAQTIKLFKVCLLRNIPIFTFINKMDREARDPFELMDEIE
                     SVLGIKTCPINWPIGCGKNFKGVYDRNTKKITTFTAAMGGQKEVASREFDLESDDVDS
                     VVGADYHSQLLDDIELLDGASEEFDMEKVSTGKLSPAFFGSALTNFGVETFLEHFLKM
                     TTPPLPRKTTEGQVDPFNNKFSAFVFKIQANMNKAHRDRIAFMRICSGKFEAGMEVNH
                     VQGGRKIRLSQPQQLMAQDRKIVEEAYAGDIIGVFDPGIFSIGDTLCAPGDKVQFEGI
                     PTFAPEHFARVRQMDTMKRKQFIKGINQIAQEGAIQIFQEFNTGMEEIIVGVVGELQF
                     EVLTYRLENEYNVDVKLEKLPYEYIRWIENKEEIDPAKIQGTSDMKRIKDLKGNPLLL
                     FVNSWSVGMVLDRNPGLVLSEFGRD"
     gene            complement(34136..35068)
                     /locus_tag="ACZPCR_06155"
     CDS             complement(34136..35068)
                     /locus_tag="ACZPCR_06155"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007706680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HIR1230494.1"
                     /translation="MRIETIQIQIEKNGAFKKTDHTAELTAYLQDSGEECRIQKRPAV
                     VICPGGGYEFCSFREGEPVALELLSKGYQTFVLRYSTAPDSFPTALLELAGAVAMVRL
                     RAAEWNIIPEQVAVMGFSAGGHLAASLGVFWNQEFLSALVKRQVQFPAGDNFRRDETI
                     FSESSLADISLLIRPDRLLLGYPVITSGEYAHRGSFDALLGELEGEEREEFLNLLSLE
                     KQVGSHVPPVFLWHTFTDTSVPAENSLLFLSALKKAGVSAEAHLFPEGRHGLALADER
                     TDKETSDGRGSYVEECCKPWAELAEAFLERWRRP"
     gene            35343..36119
                     /gene="sigG"
                     /locus_tag="ACZPCR_06160"
     CDS             35343..36119
                     /gene="sigG"
                     /locus_tag="ACZPCR_06160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HIR1230495.1"
                     /translation="MALNKVEICGVNTSKLPLLTNEEKEELFARILKGDKEAREQYIK
                     GNLRLVLSVIQRFSGSSENVDDLFQIGCIGLIKAIDNFDITQNVRFSTYAVPMILGEV
                     KRYLRDNNSIRVSRSLRDTAYKAIYARESLTKKNLKEPTLCEIAEEIGVSKEQVTYAL
                     DAIQSPVSLYEPVYTDGGDPLYVMDQLSDKKSSEENWVEDISLNEAMNRLPERERHII
                     DLRFFEGKTQTEVAEEIHISQAQVSRLEKNALKAMRAYLS"
     gene            complement(36230..36970)
                     /gene="sigE"
                     /locus_tag="ACZPCR_06165"
     CDS             complement(36230..36970)
                     /gene="sigE"
                     /locus_tag="ACZPCR_06165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HIR1230496.1"
                     /translation="MIMKAAAPSRFRMKNLPTFRALLMPGEGEIHYIGGTDILPAPLD
                     SREEARVLGELGTERDREAKSSLIEHNLRLVVYIAKKFDNTSVGVEDLISIGTIGLIK
                     AINTFNTGKNIKLATYASRCIENEILMYLRRNNKTKLEVSIDEPLNVDWDGNELLLSD
                     ILGTDEDVIYRDLEDEIERNLLKTAISHLTPRERTIVELRFGLNNADGDEMTQKEVAD
                     LLGISQSYISRLEKKIMKRLKKEIVKYE"
     gene            complement(37065..37880)
                     /locus_tag="ACZPCR_06170"
                     /pseudo
     CDS             complement(37065..37880)
                     /locus_tag="ACZPCR_06170"
                     /inference="COORDINATES: protein motif:HMM:NF015384.6"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
BASE COUNT         8557 a        11008 c         8643 g         9760 t
ORIGIN      
        1 aaaaaaaagc ctgcttatgt tccatttcag cgccagtgtc agcatacaag agacaatata
       61 cgggctgacc ttttcaagcg tgtttgaata tccgcaagca gggactgcct ctcaaactgt
      121 gaaaggcagt ccctgacggt tatttcattg attcaatttt accataagtt aatagaaaag
      181 atcaatcctt ttcagcctcc gcagctctgg cctccacttc tctcttctga acgtcgccag
      241 gagcctgctc gtagcggctg aactcatagg aatatacgcc gattccgcct gtcatggagc
      301 ggagatctgt gttgtatccg taaagctcgg acacaggaat atccgcctca atcacctgtt
      361 tgccgtggtg atcggaattc atgcccagga cgcgtcctct tcttctgttt aagtctccca
      421 taacgtctcc ggtaaattta tccggaactg tcaccttcaa ggaggcaatc ggctctaaga
      481 gaacaggatt tgcatccatg aagcccttct taaaggccat ggtagccgcc atcttaaagg
      541 ccagctcaga ggagtcaacc ggatgatagg atccgtctac cagagttgcc ttcaggccca
      601 caaccggata accggccagc ggtcccttga gaacgcattc ctgaattccc ttctctacag
      661 ccgggaagta gtttctcgga acagcgccgc cgaagactct ctcctcaaat acatagggct
      721 tctccagatc gccggagggc tcgaactcca ttttgacatc gccgtactgt ccgtgtccgc
      781 cggactgctt cttatacttg ccctggacct ccactttctt tctcagcgtc tcccggaacg
      841 cgaatttcgg tttgctgagc accatatcta ccttatagcg ggccagaagt ttgctgacta
      901 ctacctccag ctgctgatcg ccgattccgt agattaagga ctgacggttc tctacgtcgc
      961 tgactgtgcg cagagtcaga tcctcctcca tcagcttgga aagcgcggtg gaaatcttat
     1021 cctcgtcgcc ctttgtcttg gctgcatacg ccatgtaggt gtacggagtg gaaatcttcg
     1081 gcttgtggta aacgataggc gctgtgcgga ctgccatcgt atcgcctgtc tgggttacgg
     1141 tcagcttggc taccgcgccg atgtcgcctg ctttcagctc cggaacctcg atggcttcct
     1201 tgcctctcag cacgtaaatc ttctgcacct tctcctctgc gtccttgttt acattgtaaa
     1261 tcacagaatc cggtttcagg gttccggtgc aaatcttcat cagagaatat tttccaataa
     1321 acggatccac cactgtctta aagactctgg ctgacaggga cacatcgtcg ttatacttag
     1381 cggtaaagcg ctctcctgtg gaaacgtcta cgcctacgca ctcaaattta tccggggacg
     1441 ggaaatattt gtcaatggcc tggagcaggt gggagaagcc ctgggcgttc actcctgaac
     1501 ccatcaatac gggaacgata tttccctctg tcacgtgctc tctgagggct gcggaaatct
     1561 cttcctgggt aaattcctcg cctgagaagt aacgctccat atactcctcg ctggtctctg
     1621 ccaccgcctc gatcagagcg tctctgacga tgttcaggtt cttcttcgtg tactccggaa
     1681 tctcgcactc ctcgtaatcg ctcagatttg tgaaacggcg tccgcccatc ttcactacgt
     1741 ttacgaagcc cacgaatttc tcattctcgc ggatcggcac ctggaacgga gcgatctttc
     1801 ttccaaagcg cttctccagc tttaagatca gttcgcggaa gctggcctga tcgtcgtcca
     1861 tattggttac gaaaatcagt ctgggcagcc ggtactcctc gcacagctcc catgccttct
     1921 ccgttcccac ctcgatgccg gccttgcagt tcactacgat gatcgcggcg tcggccacgc
     1981 tcatagcctc ctccacctcg cctacgaagt cgaagtatcc gggagtatcc aagaggttaa
     2041 ttttaatcgg accgttctct ccgttgtact ctagcggaac cagactggtg gaaatggaga
     2101 tctgacgctt tacttcttct ttatcataat cgctaatggt gcttccgtct gcaatctttc
     2161 ccatccgctt ggtaacgccg gtcacaagcg ccatggcttc tgctgccgtc gtcttgcctg
     2221 ctccgccatg tccaagaaga accacgttgc gaatttgttt tgtcccgtac acattcatat
     2281 aaaattcctc ccgtagataa attttagtcc atgatgatat tttacaagaa aatagagaaa
     2341 atttcaagtt aaatatgcat tttacacaac atttctttca agtttctcca atctttctgt
     2401 tcatccctcc gtttttcctt ctttttcact atatcttttc gccattctgc cgatatattc
     2461 tgtttcaccg ctcataactg ctcctgtttt ctgtttcccg ccggatcgtc tctgtgtttt
     2521 tcagagaaat aggcggcagg attcgagaaa cggttgacaa ggacgtccga tatgatacac
     2581 ttgatattgt ctgaaaacag catcctattt gctgtgctat acttacaaaa acagggagga
     2641 cacactatgc agacacaaca tctcaccgca ggctttatcg gtctgggact gattggcggt
     2701 tccatcgcca gggctctgaa aaaacaggct ccgtccacta ccgttatggc ctatatgcgc
     2761 tcccgtgacc gtcttctgaa ggctcaggag gacggagccg tagacattat tttagaaggc
     2821 gtgggagagc cgctcagaca gtgcgacatt atttttctct gcacgccggt tgaatataac
     2881 gcctcttatt tagagcagat ccggccctat ctgaagccag gcgccgtcat cacggatgtg
     2941 ggaagcacaa agacgcagat ccacgaggcc gttcagtccc tcgccatgga ggagtctttt
     3001 atcggcggac atcctatggc tggttcagaa aagacaggct atgaaaattc cacggatcac
     3061 ctgctggaaa atgcctacta cattctgact cccacagata aaacgcctga atcctccgtg
     3121 gccatgatga cacagacagc ctccctcatc ggcgctatcc cgcttgtttt ggactacagg
     3181 gagcacgaca ggatcgtggc tgctgtcagc catctgcccc atattatcgc ctccagcctg
     3241 gtaaacctgg tgcgggacaa ggacggatca caggggttga tgaagcggct ggcagccggc
     3301 ggctttaagg atatcacccg gattgcctcc gcctcccccg ttatgtggga acagatctgc
     3361 atgacaaacg agacgaatat tgcctccctt ttaagagatt atatcgaatc cttgaaccgc
     3421 attttaaccg ttctggacag ccgggacagc gactctgtca gagagctgtt tgaaagctcc
     3481 agagactaca gaaattcctt tgaaacacgg gtttccggcc ctatcgcccc ggactactcc
     3541 ttttctgtgg acgtatgcga tgaacctggc gccatctcca tcatctccgc tattttagcc
     3601 ggaaagggga tcagcattaa aaatatcgga atcaatcaca accgtgaaaa cggcgagggc
     3661 gctctgtcca tcaacttcta tgacgagaag tcccgaaacg ccgcctggga acggttaaaa
     3721 aaatataatt acacactctt taatttctaa gctgcaggag gattttttat gattttttct
     3781 acgaataaag gaggtcttcg gggagagctg actgtccccg gagacaagtc catttcccac
     3841 cgaagcgtca tgttcggagc catttccaga ggcctgacgg aaatcgacgg cttccttcag
     3901 ggggccgact gcctgtctac gatcgcctgc tttcagcaca tgggcgtttc tattgaaaac
     3961 cggggaaacc gggttctggt acacggaaac gggatgcggg ggctgaaaca gccggacggc
     4021 gtgctggact gcggcaacag cggaactacc accagactgc tctccggcct tctctccgcc
     4081 cagcccttct ctgtcaccct gacaggagac gaatccattc aaaaacggcc catgaaccgc
     4141 attatcaccc ctctcagcca gatgggagct tccattcaaa gcatgggcgg caatggctgc
     4201 gcccctctcc ggatcgaagg ccggaagctc cacggaattt cctatcagtc tcccgtggcc
     4261 tccgcccagg taaaatcttc gattcttctg gccggacttt acgcagacgg agaaaccaga
     4321 gtgacagagc cttacctttc cagaaaccac agcgagctga tgctctccca cttcggcgca
     4381 gatgtaagaa cagagggaac cactgccatt ctaaagccag cagaggaact cttcggccag
     4441 cgcattaccg tgcctgggga tatctcctcc gccgccttct tcatcgccgc cgccctgatt
     4501 ctgcctggat ctgagcttct gattaaaaat gtgggcgtca accctaccag agacggtatt
     4561 ctcactgtct gccgccaaat gggcgctgac attactcttt taaacccgtc cagcgaaagc
     4621 ggcgaaccta ctgccgacct gctggtgcgc cattctgctc tccatggaac agttatcgag
     4681 ggagctgtga tcccgacgct catcgacgag ctgcccatga tcgccgccat ggcctgcttt
     4741 gcagatggag aaactgtgat caaagacgcg gccgagctga aggtaaagga atccaaccgg
     4801 attgccgtga tgacagatag cctaaaggct atgggagccg atgtggagga gacggaggac
     4861 ggcatgatca tccgcggcgg aaagccgctt cacggcgctg tcatagacag ccgcaaggat
     4921 caccggatcg ccatgacctt cgccgtcaca gccctggctt cctccgggga gacagaaatt
     4981 ctggacgcag actgcgtcaa tatctcctat ccttcctttt atgaggattt aaaacggctg
     5041 caggcgtagg aaaaaggagg aatctttatg atgctccata aaaacaaaaa aatcgtcctc
     5101 gttttattaa gcctcgccct gctggcggcg gcgcttctgg ccgtatcctt ccgcgccagc
     5161 tccgtctcct tttccagcgg ggagatctgc tctgatttaa gttcgcagga atctttttca
     5221 tttttaaaaa cttactatta cgagcatcag aatggcgaga tagaggagaa caccatccga
     5281 aatacctatc gcgccctgcc ttccgaggcc atagaaacct gcttcttcga cccggtcaca
     5341 ggagaaacct ctcctcccca gtattacgcc aaagacaatg agagctggtt tttctaccgc
     5401 tatgaaaaag acgatacctg gagcagggag aaactggaaa actttacggt aaaggactat
     5461 ttgatgacct cctccttctc gatcagcggc gttgatctgc agatagtaaa agactggaaa
     5521 caggctggaa cagaaacgct tcatgagcgg cagtcggtcc gctttgacgg aacctgttct
     5581 atggaacagt acctcaagga aaaggcgcgg ttaagtggag aagcctatat cgaaccctcc
     5641 gctgatcccg gcgggctggg aaccatccgc gtcagcgtct gggtggacaa aacgtcccat
     5701 gaggcactgc agctgcagta cgccttcccc gcgcctgctc agccaggcaa atcaggcgga
     5761 acagacgtca tcaccgtaac gctctgggat gaaaccgatc cctttgaaat tccagaagct
     5821 gcagaagtct ctgattgaca aatttttctt gaaacattct tctaaacgta gaaaaaatct
     5881 atcagcccgg cgcttagctg atagattttt ctatttcttc ctgttttaac aagaacacct
     5941 cttatggccg agggaaaatt tttggtgact ttaagtggaa caagaaaatt ttcccttcgg
     6001 gcatatcttc ccattttgcg gcttctccca ttccttttgt aatttttttc atttttctat
     6061 tgacaaacgc ttacaaaagt attaggatga tgacaaccaa aaacacaaac cgttgagaaa
     6121 gagaagtagg ccggattgat acatcacaga gagccgcgca caggtggaag cgcagtatga
     6181 agcagctggc tgaatggact ttcgagggcg ttcccgatac cggtatttgg aggtagggag
     6241 cgacggaaac cgcatccgtt atcttcgcgg catatatgtt agtatatgaa agagtggact
     6301 ttacgtcaat tatgggtggt accgcggatt tgttaattcg tcccagatac aggaaactgt
     6361 gtctgggatt tttttgtttt atccggcaga acacgcttcc cagctctcac tccttccaag
     6421 tacggcataa aaatctattt cattggagga atgtattatg agaaagaaaa caatcgcagc
     6481 tttagtaacc gcagttatgg cagtatctgc cctgacagga tgctcctctt ccgagggcgc
     6541 cagagagaca ggaaacactt cctcagaggc aggaagctct gcagcagaaa gctccaggag
     6601 cggcgaagcc cagaacagcg aggctgcaga gggcgagtat accatcggag ttgctcagta
     6661 cgcggtacac ggctccctgg ataactgccg ggaaggcttt ttaaaagggc tggctgagga
     6721 aggatttgtg gagggtaaaa atctggaagt aatctatgaa aacgccaacg gcgacggctc
     6781 cctctccggc cagattatca caaacttcgt ctccaacgac gtagatatgg tctgtgccat
     6841 cgcgacgcct atcgcccaga gcgcctacag cgtcacgaaa agaagcgata tcccggttat
     6901 ctacacagct gtcacagatc cagtgctggc cgagctggcc acagaggatc agatgccagt
     6961 aggaaatatt acgggaacca gcgataagct tcctgtttcc gaacagcttt ccatgatccg
     7021 tgagattctc ccggaagcta aaacggtggg aatcctctac agcaccaacg aggtcaattc
     7081 ccaggcagct atcgaggaat acaagaaggc ggctccggaa ttcggactgg aaattgtgga
     7141 gagcggcatt tccacctccg ccgatatccc gctggcggca gagcagctgg cggccaaggt
     7201 agactgcatc agcaacctga ctgacaacaa cgtggtaagc tctctcccgg ttgtcctgga
     7261 ggctgcctct aaaaacggca ttccggtatt cggaagtgag attgagcagg taaagagagg
     7321 ctgcctggca actatgggac tggactacat cgctctgggc gagcagacgg gacgcatggc
     7381 agcccaggtt ttaaagggag aaaaagaggc ttccgaaatg ccttacgaac tgattgaggg
     7441 cgcagccttc tacggaaata cagaggcggc agagaacctt ggcattgaac ttccggaatc
     7501 tctcacctcc tcggcagcag agctgtttga agagatttcc gaataaccgg gcgcggcagg
     7561 aaatgaggta acagacatga gcattcttct ttccatcctg actcagggcc tgatttattc
     7621 tctcatggct ctgggcgtat acattaccta cagtattctg gactttccgg atctgtctgt
     7681 agacagcacc ttccccttcg gcgcggcggt gacggcggca gctattgtgg ccggagttcc
     7741 ggctcccctt actctgcctc tctccttcgc ggccggagct ctggccggca cggccacagg
     7801 cctcatccat gtgaagctga aaatcaggga tctcctctcc ggcatcatcg tgatgacagg
     7861 actctattcc attaacctga tgattgcggg aaataaggcg aaccttccga tttacagcca
     7921 ggagacaatc tttgaaaacg agatgacagc gtctctctcc agccggagct atgagctgac
     7981 tgtagcggcc attctcctga tcctggttgt ctttgtaaag attgtcatgg atctgtactt
     8041 aaaaaccagg tccggccttc ttcttcgggc tgccggagac aacgaaacgc tggtaacggc
     8101 cctggcgaag gataagggaa ccgttaaaat catcggtctg gctctggcca acggtctggc
     8161 cgccctctcc ggctgcgtat tctgccagca gcagggcttc ttcgatatcg gagtcggcac
     8221 gggaaccatt gttacagggc ttgcaagcgt gattatcgga accaagctgt ttgccaagct
     8281 gggcttctta aaaactacga ctgccgttat cctgggttct gtcctctaca aggcctgcac
     8341 ctctatggcc atgagcattg cccagaattt tggaatcaat acttccaaca ataaattcgt
     8401 aaccgccgcc atgttcctga ttattctggt gttaagcggc cgttcattca gaaagaaggt
     8461 ggactgatgc tggaggtaaa gcacatccga aaatattata atcaggggac agtcaatgaa
     8521 atgtgcctgt ttgaggattt cagcctgact gtggagcagg ggcagttcgt ctccgtggtg
     8581 ggaagcaacg gttccggaaa aacttctctg ctaaatatta tctgcgggag tattcccgta
     8641 gattccggaa gcattctcat ccatggaacg gatatttcga aaatgccgga gtacagacgg
     8701 cagagagtca ttggccgcgt ttaccagaat ccttctatgg gaacctgtcc caacatgacg
     8761 attctggaaa acatgtctct ggcagatacc aagggaaagc ccttcaacct gcgccggggt
     8821 accaataaaa agagaattga tttctaccgg gaaaacctcc gtcttctggg cctgggcctg
     8881 gaggataagc tggacgtgaa ggcaggggtt ctctccggcg gacagcgcca ggctatggcc
     8941 cttctcatgt ccaccatgac gcccattgaa tttttaattc tggacgaaca cacagcggcc
     9001 ctggatccaa agactgcaga ggttatcatg gagctgaccg accggattat cagggaaaag
     9061 aagctcaccg ctcttatggt tacccacaat ctgcggtacg ccgtagaata tggaaaccgg
     9121 cttctcatga tgcaccaggg ccaggccgtt atggataagg cctatgagga gaaggagtcc
     9181 gtacgggtag acgatatttt aggcaaattt aatgagataa gtattgagtg cggaaactaa
     9241 ttccgcgctc ttttgactta taatcaatca gatggaggat ttttatcatg gattacagac
     9301 gatttggaaa cacaattgca gcgagaattg acaaaggcga ggaaattctg gagcaggtaa
     9361 aggctatcgc cttaaaagaa gagattaagc tggcctccat tcaggctctg ggcgctgtga
     9421 atcagtttac tgtgggcgtg tttaaaacag atgagaaaaa atatatggcc aacgattttg
     9481 ccggcagctt tgaaatcgtg tccctcacag gaaccatcaa tactatggac ggggagtttt
     9541 actgccacct gcatatgagc gcaggcgacg acaagggaca cgtattcggc ggccatttaa
     9601 accgcgccct tgtcagcgcc acctgcgaaa tgattatcac tgtcatcgac ggaaccgtag
     9661 accgggcctt cagcgaagaa gtgggcttaa acctgttccg tttctagctg cttttcgtaa
     9721 gcttctgcct ttccgctccc ctctgccctc atccgttcca tagtggatcg gatggagccg
     9781 gtggggcata cggatttgca gtctccgcag cggatacact ccgggctgtt gggcgtcttc
     9841 cacaccctga tgtccatttt gcagaccttc tggcaggcgc cgcactggat acaggttttt
     9901 tcttctatcc ggaaccgata gagagaaatt ggattaaaga gtccgtaaat ggctcccaga
     9961 gggcacacat atttgcagaa gggcctgtag tatttcatgg acaggacaac tgtcaggacc
    10021 agcagaaaca ccttccagct gaacagcttt ccaagggcgg tgcgcagcat tggatttcca
    10081 agtcccagag gcagtcctgc catcagcgtc ccgctggggc agatatactt gcagaaccag
    10141 ggatttccgt ttcctgtcac tcccaccgcg agagacggca gaagaatgac aaaaagcacg
    10201 agaatcacat atttcatgta gattaagaac ctgtgtcccg gcaggttctt tttctttcca
    10261 ggaaagggaa ttttatggag cagatcctga accaggccga agggacagag ccagccgcag
    10321 atgaaccgtc ccagcagcgt cccaaacatc ataagaaagc ccagaacata gcaggaaacc
    10381 gtaaagctgc tgctggaaag cactgcctgg agagagccga tggggcatcc tgccagagcg
    10441 ccggggcagg aatagcagtt cagtcccggc acgcagaggc tctttagttt tcccgtataa
    10501 atcttcttct ccagaaatcc ggcggcatat ccgtttgtaa gggcaaacca ggcggcctga
    10561 cacaacagac gcaggcggcg cgtcctgcca agccttcctc ccttactccc cctgttaccc
    10621 aattccaata cactccaaac agatattcgc cgcctttata aacactgtcg ccgcctctcc
    10681 cctgtaaact ccggctgcca gaagaacagc tgccgttaaa agcaggccgc cctgcacagg
    10741 gccaaaggcc ttttttctgt ctgtcttaca cttcatcgtt tcgttcctct ttccttccag
    10801 cttactggac agaggcgaga acttcgtcca ggatcccagc ccatccttcc ttgtctctgg
    10861 ctcccatgta ggcggttccc acctgggttc cctcgctgtc cacaaaaatt gtcataggca
    10921 ctgccatcac ctgcggaaga agcgtgtcca ccagcgttcc ggacatggcg atatggggat
    10981 aatccgcccc tgtctgctct gccagctctc tggctttctc aagctgggcc tcgtccagtt
    11041 ccttatccgc gttaatggta tcagaacaga ttccaatgat ctggacgccc ttctcctggt
    11101 actcccggtt cagctcagcc agatccggca tctcctccag gcagggagtg cagaaggttc
    11161 cccacacgtt aatcatggta agctctgcgt cctcaaatat ggtctcgtct acctggtttc
    11221 cgtctaaatc ctgggctgta aaggactcga acactccgct gctctccttc tcaccctgtt
    11281 tcttttcttt cgtttcagaa gctcccgtac ctgtcttctc agaaacagcg gctgaagcat
    11341 ccggctctgc tgcctttccc tggcaggcgg tgagagccgc cgctgtcata cacgctgcta
    11401 aagcgatccg atatcttttt ttcatgaatt gactgcctcc tgttttgctt tttattttta
    11461 ctttttatga tttcaatgcc tttgaaagcc ttttcatctc tgtcctgcgg cgcttttgtt
    11521 ccctttgcgc cgcgttccct gataatacca tgaacgcctt aaaaagacaa tccatttctg
    11581 tctatttttc ttccttttgt ccatacttat aaatataatc cacagggaaa ggagtctctc
    11641 ttatgacaca ggatattgaa cttttaaatc agattcatca aaatgcagat atggggcgcg
    11701 acagcgtccg ccatgtgatt cagctctcca atgacgttca gtttctccac gcgctgaatt
    11761 cgcagctgga cgagtacgaa ctggcctacg aggaaagcgg cagaatgctc agagcccatg
    11821 gggctgccgc ggaggatgca agccctgtcg ccaaggcaat ggcccgggtg tcctccacca
    11881 tgaaaagcct ggtaaacccc actacctcca agctggcgga aatggtcatc cagggaaaca
    11941 ccatgggcgc tacggaatta aaaaaacagc tgaacgccta ccgcgggtct aacccgtctg
    12001 tagtcagcct ggcgcagcgt cagctgaaat ctgaggaaaa aaatattgaa gatatgaaac
    12061 agtatcttta agctgacaga aaaaggaagg gcgtgaaaaa ccagcgtttc ttactccctt
    12121 cctttttcat cattagtagc ccagctgtga aagaatctgc cccggctcac cgatgagcgt
    12181 caaatctgcc ttctcatccg agtagtgggg cgttctgtgg agcaccgcca gatattttcc
    12241 gtgaaaatat ttgagataat tggaaaatgt ctctgagcgc agcgtagttc ccactaaaag
    12301 cagcacctcc gccttctcaa tctcctctgt ggttctggtc ataatgcggc tgtccaccat
    12361 ctcgccgaac agcgacacct tgggacggat cgtcgcgttg cagacccggc agcacggaat
    12421 ccccttcatc tccagaatgt cttccaccgt atacagctcc ccgcatctgg gacactgatt
    12481 ctcgtacacc gttccatgca gattaatcac gtgctcgcag ccgccgcgga tagcctggtt
    12541 aaatacgttc gccgtaatga cgcactgaag ctttccggcc tgctccatcc tggccatggc
    12601 atagctcccc agaccaggat ccggaatata tctgagcacc tcctccttat aaaagtgaaa
    12661 gaactgctcc ggccttgtat tgtaataggc gcttgtaaaa atgtactccg gggaagcgcc
    12721 gtaggctctc tcaatggcat aggcccggtc tggattctta attcccctga cgcctccgtc
    12781 tgtcagcata ccagatccgc agagcgctac tgtataatta ctctcatcca gcattctttt
    12841 gagaactgct attttttcct tcataaacat gtcctcctct ctttcccttc aggccctgtc
    12901 tatggaactt ctatttgtaa ttatactata tacgccctgt tttttctatt acttctttcg
    12961 cattttcttt aaatttccga taatttcagc ctaatatttg aaattgagga aattatatgg
    13021 ctgtaatttc ggcaggaaaa aaatcttttg cttcttattt taatgcctgt cctctgccga
    13081 aagctgagac agctctgcgt ataccggcgt gcccagtccg aagccgccag acacggcgat
    13141 cacctgccct gtcgtgtagg ctgcctcctc gcttccaaaa tacagcactg ccgccgcaat
    13201 ctcctccggc gttcccattc tcctgatagg cgtgtggcgc agaaacagct cctggaagga
    13261 atccgacata ttgttcttta ccgcgtctgt agccgtctgt cccggacaca ctacgttgac
    13321 gcggattccg tttcttccct cctgaagggc gatatttttg gacagataga tgatggcgtc
    13381 cttgctgact gcatagccga ttctggcaat atccggaatc tgcccgccga tggagctgat
    13441 attgacaatg cttcctcctc cctgttttct catagcagga agcacagcct gagtggagag
    13501 gaatacgctg gacagattct tgtccagagt atccagaaaa tcctcgtacc tggttctggc
    13561 aatatccaga tccgttctcg gatctgaggt tccaaagttg tttaccagaa cgtcaatccg
    13621 tccctccgcc tgttccacag tctctgccat agatgtgtag gactccttca ctgacgcgtc
    13681 gcagtaaacc catttggcct ggcccggctc tcctgaaagc tcctcgattc tctttttagc
    13741 cgcctcctcg tttctggcag ccagatagac tatggctccc tctctcacaa aggcctgaac
    13801 gcaggcccag ccgattcccc ttgtagacgc tgtgacaatg acaacctttc cttttacgtt
    13861 catatagctt ctcctttctg tctgccctct gcagacggag cctgacagcc gaagcacttg
    13921 accttgtggc cgttttccag gctcatcgtt tccggtcttg acagggcgca gcgtccgctg
    13981 cgctttggac atctggggta gaagggacag cctgcgctct cccgcccaaa gttctctcca
    14041 atgtcagaga ccagttcacc aggatcgttt ctttcagcct tttctttctc actgttttcc
    14101 cccagggagg aggccagcag aagccttgta taggggtggc agggattgtg gtaaatctcc
    14161 tctaccgccc ccgactccac tacctctccc agatacagca ccgccacccg gtggcagacg
    14221 cggcgcacta cattcaaatc atggctcaca aacagaagcg tattttttct ctcctcgtgc
    14281 atatccagaa gaagctttaa aatctgagac tgcaccgtca cgtccagagc ggaaaccggc
    14341 tcgtcggcca ccagcagcct ggagtccgca agaagagccg ttccaatgct gattctctgg
    14401 cgctgcccgc ctgacagctc tctgggacgg cggctgtaaa agctctcgtc cagaccgatt
    14461 ttgaccagca tttcctctgc catccgcttt ctctcagccc ggtccgagac gcccctcacc
    14521 cggagaggct cctctaaaat ccatccaatt ttcttggccg ggtttaagga tccgaaagga
    14581 tcctgaaaca ccatctgggg gcgcagatcc ccgtcggtct caatggttcc ggaataatct
    14641 ctgttaagcc ctgcaatagt cttggacagg gtggactttc cgcagccgct ctcccccacg
    14701 attcccagga tttccccctc tctcacagac aggctcacat cgctgagcgc cttttttctg
    14761 gaggccttct taaaaaagcc gcctccttcc ctgtaaaata cgtccagatg ggaaattttc
    14821 aaaatctctt tctggctgtc cgccctgccc gttttctccg ggatggacgc caccagacgc
    14881 tttgtatatt catggcgcgg gctgttcaat acctgctccg catcgccctg ctccacaatc
    14941 acgccctgat agaccaccag cacccggtcg cagatttccc gaatcacgtt taaatcatgg
    15001 gaaataaata aaattgaggt ctggttctcc tggtggattt ttttcagaag gcggagaatc
    15061 tgggcctgca caatcacgtc taaagccgtg gtaggctcgt ctgcaattaa cagcctgggg
    15121 gaagcaatca tggcctgggc aatcatcacc ctctggcgca tgccgccgga cagctcgtgg
    15181 ggataccgat ccagcagagc ctccgcctcc gaaagtccca ctgcctgcag cgcttttaca
    15241 catttctcat ggatctcctc tttagaaaga tccgtgtgga gcgccagatt ttctcccacc
    15301 tgctttccaa tcttcataac agggtttaag gatgtcatgg gttcctggaa caccatggca
    15361 atctcctctc cctggatctt ttcccgctcc tgcccggaaa gctgcagaag atccacaata
    15421 tttccatcct ttttgcagaa ttcaatgctt ccgctcttca cctgagcgct gtccgggagc
    15481 agtcccataa tcgaaagggc gctcatggat tttccagatc cgctctctcc caccactccc
    15541 aggatttctc cttcatagat aggaaagctg atctttttta caacctcctc ataaatgcct
    15601 ctgtccgtaa attcgatgga taaatccttt acgctggcca gaatcttttc ctgcttcctt
    15661 ctcttctctg tatcctgtcc catatcgcct ctcatcattc cttgaaacct tttccgtctg
    15721 ttttgtctgt gccttgtcta cttctgaagc tcccgaagtc cctctccaat catggaaaat
    15781 cccaaaataa tgaggataat cacaattccc ggaaaaatcg cataccaggg agcgccgaac
    15841 agaaaggact gggcctcgga gagcatccgc ccaagacttg gctccggcgg ctggactccc
    15901 agtcccaggt agctcatccc ggcttcagac agcaccgcgt tgttaaaagc aatggcagct
    15961 gtcgtcagaa tgctgacgga ggcgtttggg agaatatgga taaaaataat tcttaaattc
    16021 cccactccca ttaccttcgc gctcttcaca aagtctaact cccggcagcg tatcacctcg
    16081 cttcgcacca ttctggcaaa taccgggata aaaataattc ccagagccag gataatatta
    16141 tattttccag gtcccagaag gctgataaaa atcagagcca gcagaacgct tggaaagctc
    16201 ataatcatat ctcccacccg catcagaaca ttgtccagga ctcctccgta gtacccggtc
    16261 agagcccctg ccgccgtgcc gatcacgcct ccgatgagga ccgtacagac tgccacaaaa
    16321 aaggtatttc cgctgccgtt catcacgcgg ctgaaaatat ctcttccaaa gttgtctgtc
    16381 cccatggggt gagccagaca cggagccaga tttacatgga gggaatccat ctgcgtgggc
    16441 ggatacggag tccagaactg tccgatgact gcccctgcca gaaaaaacag ggtaatcgcc
    16501 agtcctatga ttaaattcca gtttcgtttc tttttcacgt ctttttcctc cgcttatgat
    16561 gtcctgactc tcggatctaa cagctgatac ataaagtcta ccaggaaatt caccgctacc
    16621 accaccagag taatatacat gacaatggcc tgcaccaccg gataatcccg gttaaaaata
    16681 gaactgatca gaagtctccc cactccgggc acgctgaaca cctgctccac aataatgctt
    16741 ccggccagaa tctccgccac caccatggct gtgaaggtaa taactggaat catggcgttt
    16801 ttcagcacgt ggacgtagag aatccttctg ctgctgtttc ccctgctctt cgctgtcctc
    16861 acatagtcct tagacagctc tgacaacacg gcatttctca aaaacttcac caccatggca
    16921 attttcggaa gagccacggc cagggccgga aataccaggt aggacgccgc cccaaagaag
    16981 ctctctgacg gctctacaaa ctgtcccggc tgaaaccagt gcagcaccag gccaaaggcg
    17041 tatgtcaaga gaatccccag gaaaaaagag ggaaccgcca tcacggtctg aagaatctga
    17101 ttgactgcat ggtccaacac tcctccggct cctctggcac acaaaagccc caggggaacg
    17161 gaacatatca aaatcataag gagggatatc accgccagca tcacagtaac tggaagccga
    17221 tctgacagaa gttctcccac cgtcatattg tcataataat aggatgcccc aaaatctcct
    17281 ctcaccgccc cggacagcca gtccacatac ctgacgggca ggggagcatt aagccccatc
    17341 tcttctcgaa acgcttctat ctgctcttct gtcgcatcat cccccaggcg ggccagagcc
    17401 gcgtctccgg gaataacaga aaaagcagtg aacgtgagaa gggatatcag caacaatgtg
    17461 ataatgagag taactaattt cttgataaaa tatttcattg atatcctccg gcgattcact
    17521 gccttttatt attttttatt taattctgaa ctcagagccc taatttgtct ggtataccac
    17581 cgacatatcg tctcctgcgg tcggatagaa ggtatatccg gcaaactcct tgtttaccgc
    17641 cacaaaattc gccggatcct gaatgtagac ggaagccgca tcctctgcca gaatcatctg
    17701 agcttccttg tagaacgcag ccttctcagc ctcgtccact gccgtatagg ccttctggaa
    17761 ggtctcgtcg tattccgcat tggaatagtg catgaaattc ttgctgtctc ccgtcacgta
    17821 tttcctgagc cagtcgttgg gcgctaaagt tccgtcaaag cctacgattg tggcctcaaa
    17881 ctttcctccc ttgtacacgt cgctgagcca ggtgctccac tctacctggt taatggaagc
    17941 gttgattccc acctgcttta actcctccac tataatctga gcggtgtcca catgctgaga
    18001 gtaggcgctt ggcactgtga tctccagatc aaagccgtcc gcataacctg catctgccag
    18061 aagctgtttg gccttctggg gatcatagga atacaccttt tctgtctccg gctcatagta
    18121 gacagacatg tttggaatca tgtgggttcc tataatgcgg ctctttccgc cgaacataaa
    18181 ctgattgatt tcgtctctgt tcaccgcata gcagagagcc tggcgcacct ctgccttgga
    18241 cagcggctcg tagctgctgt tcaaaaacat tccctgcacc agattcatgc tgccctcttc
    18301 aatcttaaac tgatcgccta aggtctgcac ctgggtgttg ttcaggtatt ttaaaatgtc
    18361 gatggttccc gcctgaagct ccataaaagc cgtatccacg tcagctgtga tcttaaaggt
    18421 cacctgatca aggtatggaa ggttctcctg ccagtagccg tcgtattttt ccatcacaac
    18481 tgactgtccc ggcgtgtagg agacgaaccg gaaggggcct gtgccaatgg gcgtcccagc
    18541 cggatccgca ttggaagccg ggatgatata ggcctgggac agatcggaca gaaactctga
    18601 atagctgtcc gtcagcgtca cctcaacggt tttctcatcc ttcaccgtca cctctgaaag
    18661 catagaaaaa gcggagccct gattggcctc cgcacatcga tcaatggaat atttgacgtc
    18721 ctcagcagtc actggagcgc cgtcgtggaa ggtaattcca tctctcagag tgaaggtata
    18781 gatcttcgca tcctctgaaa tctgataatc actggccacc gccggtatca gactgccatc
    18841 tggagcgggc tttacaagcc cctcatacaa attaaaaacc acatctctag ttcctgcgtc
    18901 cgtcgtagcg tgggggtcaa gactagccag gtcctgcgtc atgcctacta cgacgcttcc
    18961 gcctggtctg ggtgttcctt ctgaaagagt attaccttct gtttctgcgg cggacgtact
    19021 gtcacctgcc gctgccgagg tgccttctcc attcttgccg ccactgcatg cgcagagtgc
    19081 agcagatacg aaaagcgctg ttaaacctaa aagaattttc ttctttttca tcattttttc
    19141 ctctcactta tccgtaatat tctctcatta ttcaattgtc tcctacattg tagcagattt
    19201 tcttaaaatt tcaatccttt tttcctgcct ttttttcagc ccccggcgca gtcttgacgc
    19261 atcctgttgt ttttcgttac ttcctgttgt cctcctgttt ctgctccaga cagacgataa
    19321 aaccccctgc tgctgtcaaa gacgcagagg gggcgcgctt atgctgtaaa atgatagtat
    19381 catcttattc ctgtacggag aactgatcct ttcctactcc gcacagagga cataaccaat
    19441 cttccgggat atcctcaaaa gaagttcctg ctgccactcc gttatccgga tctccctcag
    19501 ctggatcgta gatgtagccg caaacgtcgc aaatatattt cttcatggca aattcctcct
    19561 gaattgtgaa atctaatttt gtttcttgtt atctgtcgat ggatttagta tagcacagaa
    19621 aggagcattt gtccagcaca attttaataa aaattactat tattgtttta aaacagttat
    19681 cagagcttcc ggctccttct gccagcaggc atctattcca gaagcctgag aatctcttcc
    19741 cggttcagtc ctgccagaga tactgttcct gttgtcacaa tccggtctgc cagctctctc
    19801 tttgactcct gcaggcgcag gatattttcc tccaccgttc cctttgaaat caggcggacg
    19861 actgtcacct ggcgcctctg tccaatccgg tgggcccgat ccgaggcctg attttccgcc
    19921 gccgcgttcc accagggatc gtagagaatg acaaagtcag ctcccgtcag attaagcccc
    19981 gttcctcccg ccttcagaga aatcaaaaac acctgggcct cccctgcgtt aaatctggcg
    20041 gccaggcggt ttctctcttc cttcggcgtg gatcctgtca gagtgaagct gtcaatcccg
    20101 ctttcagaaa gccgcttctc catcagggga aacatggagg aaaactggga aaacagaaga
    20161 attctgtgtc cggcgggaac agcccccgca atcacatcca tacaggtatc cagctttgca
    20221 gagcctcctc tgtaattctc atagcacaga gacggatcgc agcagatctg cctgagcctt
    20281 gtaaggcctg acaaaatctt aaacttctcc tccccgctct ccacttcctc cttcaggcgg
    20341 agtacgctgg ctccatagag cttcttctgt tccccggaga aagcggagta aacgatcttc
    20401 tccacttttt ccggaagttc tttcatgacg tcctttttca gtctcctcag cacaaagggg
    20461 ccgatcaggc ggcgcagatt cgaagccgcc gtctcgtttc cctccttcac aatgggtatc
    20521 tcatagagct tcctgaactt ctggtaggaa aagagaaatc ctggcatcag atagtcgaaa
    20581 atactccaaa gctctcccag atggttttcc accggcgttc ccgtcagggc aaaccttgtt
    20641 ctggccctga cagccttcac cgccttggcg ctttttgtgg cggcattttt aatgcactgg
    20701 gcctcgtcaa tgatctggaa gcggaacttc tgtttttcgt accactcctg atcccgtttc
    20761 agaagctcat aggaggtgat cactacctgg tactcttcca tccgcgccaa cagctcccgg
    20821 cgctcgctca tggttcccgc tgccgtgacg gtctttaagg aaggagcgaa gcggtacagc
    20881 tcatgctccc agttgtaaat cagggaagcc gggcatacaa tgagggacgt cccctcctgt
    20941 gctgcggaca gcagaagggc aatcacctga atcgttttcc ccagtcccat atcgtcggcc
    21001 agaatccctc caaagcccca atgatccagc gtcctgagcc accggtaccc tgtcttctga
    21061 taagccttca gctctcccat aaaggatgac ggcacgtcgt aatcgctgtc ctccactgat
    21121 ttcattccgc ggatcagcgc tttatagccg ctgtctcttt tgagggaaat atgcccgtcc
    21181 tccctgaggg cctgatccag atacagggcg cggaagctcg gaagaaggat ggtctttttt
    21241 gcaagctccg cctttcccag ggacaggccc tcccgtattg tctcaatggt cataaagccg
    21301 tcgtccgaca gttttaagaa ttccccattt ttcagccgat aatacttttt cttctgcgta
    21361 taggcgtcca gaacctttaa aagctctcct cctgtcagat ctcccgtatc cacggtgagg
    21421 gtcagccatc cgtccgaggc agaaactccc atggaaatct ccggcggccg gcggatcgta
    21481 agggccttta cgctccccga cagccgtatt tccccaagag aacggaattc ctccatcccc
    21541 tcgtctaaca gacggtaaac cgcctcctcc ccctccggca gaaagagacg gcccgcgccc
    21601 tcctccctgg cagcaaaata cctggtaatc agccggctga tccggaactc tcccggcacg
    21661 tcccggcaga tgcttttggg cacgtcccca tcatccagcg ggtgaaagct gtaatctccg
    21721 taggaaaggc ggggaatcag gcagagacgg cctttttcgt cgcagtcaaa atcaaacaca
    21781 gcctctaatg gctctggtct ccagttctcc agctccaccc cttcctggga caggatgcca
    21841 agaggctcca ttctgctcag tacccgctcg taaaacaaag gcacgtccct ctcatgtatg
    21901 agaagttttc ccggctcctc ctgccctccc agtatcccgg tcagaaaaat ccccatcacg
    21961 tttccatatt ctgtgctgca gcaaaaaatg tgatgttcgt ccgccacata cagtcttttt
    22021 tctccctcaa aggctgccat ccctgagggg accgtaacgg aaattccact ttttccagcc
    22081 cgttttacca atacggcaaa atcaggatcc tctcttacca ctgtgagttc tctttgctgc
    22141 cccctggcgt cctcgcaccg gatcgcccgg cctgtattca gaccaaagaa ccggtctaag
    22201 tctccccggc tcagacggag cgcccgcagc gcaggctctg caggcattcc tccccttcgt
    22261 atctgtctgt aattctccaa atatgaaaag gccagctctg ccgtaagcct ggctgtcttt
    22321 ctgctctcct ctgtaaatgc ctgaaaatcg tggttaaagg ccagacctct gccatactcc
    22381 acataccggc cctctctcat tgccagggcg aacgaagcca ggtcctttaa ttgatactct
    22441 cttctctttt tgagtcccgc ttccataagg atctctctcc tgctgaacag aaggcgcggg
    22501 atgaattcta cctctccttt ttcctcctcc gccacaatct gagctacctg gcggtttgtg
    22561 tactctctga tcatcagccg cgccgacgag gaggtaaaca caggccgcgc cgcctcaggg
    22621 ctttccgaat ctttataaac ctggtatagc tcctgcccgt ggctgcagac tccccgaaaa
    22681 gaattttccc tgcagcagga gcaagaatag tctatgatct ggctgccctt gacataaatc
    22741 tttgtctgat aaaccgctcc ctgatcctcc acctggccag agacgcggac ttcccccttc
    22801 cagaaagtat ccacagaaat atcttttacc gccatgacgc tccttttccc ctgtcttccc
    22861 gcatatgcgg cgaagctgcc ggacacagtt ccctgtatct tagcagcttc gcatcatttg
    22921 attcatccta ttttaatggc tcttacatgt gttccggagc ttcaatgccc agcagatcca
    22981 tgcaggcgtt cagcacgtcc ttcgtgaggc tgatcaggct gataaagcct gcctgcttct
    23041 cgcgatcctc ctcgccgata atcttgttaa ccagatagaa gttattgaac gcgtctgata
    23101 aatcgtacat atactggcag atacggtgag gcgcagtctc cgcaaaggca gtctcaacta
    23161 cctctccgaa acggcataac tccagctgaa gagccttctc cgtctcagag gaagccgggc
    23221 gtacaggaac cagggtatag cttccgccca tcagttctct gtacttctca agaatcgact
    23281 tgatgcggac taccatgtac tggatgtgtg gacctgtatt tccctcgaag gaaatgaagc
    23341 ggtccacgtc aaatacatag tccttggtag cctggttgga gagatcgccg tactttaatg
    23401 cagcgagacc gatcatctcg gctgtctttc tcatctcctc ctcggatact ctctgcttct
    23461 cctggacctt cttgtaaact tcctcattaa tatctgcaat caggcgctcc agacgcataa
    23521 cgccgccgtc tctcgtctta aaggggcctc cgtccttgct gttcatagtg ccaaatccca
    23581 ggaataccat cttggtcttg tcacttacaa tgccggcctt cttagccacg cggaacacct
    23641 gggtaaagtg aagctcctgg cgcttgtcca ccacgtagat atagcggtct ggatggtaat
    23701 cctgctctct ctggacaatg gtggccagat cagaggtcgc gtaaagagca gctccgtcag
    23761 actttctgac gatacaggga ggaagctcct tggtatctgt ctcctcagca atgtccacca
    23821 ccagggctcc ctggctctcg taagctaatc ccttctcaac caggtcgtcg atcagctgcg
    23881 gaatataagg ctgcgcgtcg ctctctccct tccacagatc gaaggatacg ttgagattgc
    23941 cgtaatttct ctttaaatcc tttaaggata cgttcataat gtgctcccag atagcgcggt
    24001 agggagcgta gccgctctga agcttaaagg tagcctcctg ggctctctcc ttgaacgcct
    24061 catcctgttt ggacttggcg ctggcagccg ggtagatctc ctccagctcg gaaatagtaa
    24121 acggcggctc cttgggatat tctcccgtaa agttctcgtc aaagtaggga agatttggct
    24181 gtctgtcgtg aagctcctcg ataatcagtc ccatctgaag gccccagtcg cccagatgca
    24241 cgtccccaat taccttatgt cccatatagc ggctgatgcg cttaatgctc tctccaatga
    24301 cggcagagcg cagatgtccc acgtgaagag gcttcgccac gttggcgccg ccgtagtcca
    24361 cgataatggt ctccggctcc ttcgtctcct ccagaccata cttgggatcc tccgccatgc
    24421 ggttcatata cccagccagg tactccggcg caatcctgag attgataaag cccggcataa
    24481 cggcgttaat ctcggagaac atagcgctct ccttcgcctt ctccaccacc tcgcctgcaa
    24541 tatcaatcgg cttcttctta tatgccttag cagcggccat ggctccgttg cactgatact
    24601 cgcacagatc cggacggttg gaaactgtga ccttcacata tttctcatcg tatccgcagg
    24661 cagtaaaagc aggcgtcagc tccgctacaa ttaaatcaat catcttctgc atgatctcgt
    24721 ctccttcttg tcagtgtttc tgatgcctcg atccccggca tcctatgttc ctatatacta
    24781 taaaatattt ttgcgctaag ttcaagacta taaagctgcg ggacatttat tccttcatgg
    24841 cttccttcac atccttcagg aactccttcc attcatcggg atgatccaca aagtatttgg
    24901 ggcaggcctt ctccgtaata tcataatggc ggatcacatc tttgggcttt aaatccagct
    24961 cccggcacag ccacgccgtc aggcgcacca gggaggcgta ggtctcctcc gtaaacctgc
    25021 cgtcctttcc cgggtggcag cactcgatgg aaaccgtgtc agaatttctt gtgttggacg
    25081 cgtaggccat ctcgtcgatg ggcacgcact ggataatctc cccgtccata ccgataataa
    25141 aattgctgct caccgaaatc cggttagagc ctgtctgatc cttgagcccc tcaaaataat
    25201 tcctgttctg ccgggctgtc gttccgggat ttcccacata gtggactact atcccgttga
    25261 tctcagaaag ctttgtgcct ggtctggaat aatcgttcag cgtgagcaga tcctgcgtca
    25321 cccactcagg cgtctccaca gacgagggat tcaccggttc tctgatgagg cttcctctca
    25381 gaaaccatcc cgccgctcct ccggacagaa acagaatcag cgctgccgca gccagaaacg
    25441 tccttctgct tctcctgcgg cgaagccgcc gtccctcttt taattttctt ctttcgtatg
    25501 cttccggctc ccttctccga cggcctctcc cctcttccag ggcctccccg gaacgctggc
    25561 gcctgttctt ctctctcatt tcctcgtaca accccatcgc ccccttttcc gtgcaggcgt
    25621 cttttcatct gtatgtttct atctgatgat ggaaggaaaa ggtatcctgg ccttctgata
    25681 ccggattctt ccgggaaaca aagaaactgc tgtaaaatag ccctgggaaa gatattttac
    25741 aacagttcct gattctttta ttcagtcaag ccgtccgctg cagaaatctg ctgaatctgc
    25801 attaaactct ggacagatac tctcctgtac gtgtatcgat cttaaccttg tcgccgatct
    25861 ctacgaataa cggaacgtag atgattgcgc ctgtctctac agtagctggt tttgtagcgc
    25921 ctgtagctgt atctccctta aggcctggct ctgtctctgt gatctcaagc tctgcaaaca
    25981 gaggagcctc tacggagaat acctcgccgt tgtgagaaca gatcttaacc atatcgttct
    26041 ccttcacgaa cttcagagcg tcgccgatct gctcagctgt aagagctacc tgctcaaagt
    26101 tctccacgtt catgaagtgg aacagatctc cgtcagagta cagatactgc atatctactc
    26161 tgtcgattct ggctgccggg aacttctctg tcggtctgaa agtcttctcc acaacaccgc
    26221 cgttcttgat atttttaagc ttggttctta cgaacgcagc gccctttcct ggctttacat
    26281 gctggaactc gacgatctgg aatacgtttc cttcgatttc cactgtaata ccgtttctaa
    26341 aatcgcccgc tgataccata aatgatattc ctccttgaat gatctctctt tatctttttt
    26401 attctatact ataatatgcc gtttttcaac tactttttgc aaaagccgca atctcccgcg
    26461 cgatttcgcc tggcgttctg ccgtctgtat tcaccgtgat atctgctgct ttttcgtaga
    26521 ccggccctct ggcaaccatc aggccttcca ccttctctct cacatttcct ccctgcagaa
    26581 gaggcctgct ggtatctccc tgaaggcggt gcagaatctg cccaggagaa gctttcagat
    26641 agacgcacac tgcgttttcc tttaaaagcc tctggttctc ctctctgaga accaggcctc
    26701 cccctgctga aatcacggta aagccgctgt ctctatccgt ctgtttcaga agccttctca
    26761 gcgtatctgt ctccattttc cggaagctct cctctccctg gagacggaaa atctctgaaa
    26821 ccgccatccc tgcctggcgc tctgtctcct gatccgtatc gcagagagcg cagcccagaa
    26881 gatctgccag atcctttccc acgcttgtct ttcctgctcc cataaagccg atgagaacca
    26941 gatgtttctg ttccggctga agccttttct ggatcagggc ttctgccagg gccagggttt
    27001 ccttctctat ctttgtgcca ggattccaca gctcatagga ggccgctccc tgatatacca
    27061 gcatcttcag tccattgacc gctctgcctc ctgcttcccg taccaggtgc ataaacttcg
    27121 tctccgcagg agtgtaaatc acatccagag cctcctctat caactgataa aactctctgt
    27181 cctctatagg agccgcgtcc accgccggat gcatccccac gctggtgcac tgaatggcca
    27241 gataccgttt tccaggcagt tccttccact gggaaagggg gagggctttc attaaatctc
    27301 tgcctgccat tctgtttccg tactctgcca gctcctctgc cttttccagg cttctgttca
    27361 gcacagtaat gcttcccgcc ttgcccctgg ccatcatgca gactgccgcc ctggcggctc
    27421 ctcccgctcc gatcagaaga cagtccctgc catttacggc aaagccggct tcctccacag
    27481 ctcttctgag gccctcaacg tctgtattat atcctttgta tccccgctcc gtccggacca
    27541 gcgtgttcac agcgccgacc tccctggcct cctcgtcgac gtcgtccagg tatttcatca
    27601 cctcctgctt gtggggcacc gtcacattca tacccaggat gttcagggca aaggctcccg
    27661 aaactgccgc ctgcagctcc tcctctttga ccttaaaggg aacatagacc aaatctgtcc
    27721 ctgtgctctc cgcataaaga ttctgaagca tgggagacat ggagtgctcc accggattcg
    27781 ccaaaatccc gcagactctg gccgttcctc tgacagactc cgctgcctgg atcatccgtt
    27841 ccaaatcttt cggctgtttc ctcatctctt ctctctctgt catctttctt tactctttcc
    27901 ctgcttcccg ctctctcttt ctgcagtctc ttctgtaaaa gtacagcacc accgcttcca
    27961 gacggcgttt taaaacaatc tgtatttcct cttttgggtg gataggcttt gtgagaatcc
    28021 cgtaaattcc cgccctgttt gcgccgtaca cgtctgtaaa cagctgatct cccacaaaca
    28081 ggcttgtctg tctgtccgtc cccatcagag ccatagcctt ctcatagccg cccctcgccg
    28141 gcttgccgcc tttatagata tagggagaat ccacctgggc ggcaaaggag gccaccctcg
    28201 gctccttatt attagacaaa agacaggtct tcatccccat ctccctcaga cgtgcaaaga
    28261 gctgcagcgc ccgatcatcc gccggcgcgc cgtggggaac cagcgtattg tcaatatcaa
    28321 aaatcactcc gcggattccc tgtctgtaaa aatcctcata gggaatgtca taggcggagt
    28381 ctctgtattc cttcggataa aatgctctga acatactagt ccttcttcaa cagctttccg
    28441 atctcttcca tgaaggttcc cacgtcctta aactctctgt acacagaggc aaagcgcaca
    28501 taggccacct cgtccagatc ctttagctta tccatcacca gctcgccgat ggcagaggtc
    28561 tcgatttctc tctcctcctt gttaaaaatc tggttttcga tctcgtcaat ggtctcgctg
    28621 atctgctgcg gtgaaaccgg acgcttatgg caggaatgaa ggataccggc ctcaatctta
    28681 gaccgatcgt aaagctctct ggagttgtcc ttcttgatca ccatcagcgg catcgtctcc
    28741 agcttctcgt aagtggtaaa ccgtttcccg catgtctcac actgacggcg gcggcggata
    28801 gaactgttgt cgtctgccgg tctggagtca atcacctttg tatcagaagc attacaaaat
    28861 gggcatttca cattcttttc ctcctgtgtg atatattgtc cttattttaa cgtactgccg
    28921 gaagatatgc aagctgtttt cagccttttt gctccttttt gcacagctcc accagaataa
    28981 tatcgtcccc gatctgcttc acgtcccgcc atggaatcac atactcgctc tcccttccca
    29041 gaaatcccca cagacatcca ggtcccggaa tgatgagggc cgtcactctt cctgtgcaga
    29101 tatcaatatc cacgtccccc acaaagccca gacggctgca gtccttaata ttgatcactt
    29161 ccttttgctt catttctgaa agacgcatag ataaactcct gacagacctc ttggttccag
    29221 tatatgacgg ctggacgcta aattgccctg cccccggata aaatccggcg ggcagggcgt
    29281 tttctctgct ctaatttcct actgctgggg cgcgttgtcc tgagcgtaaa tggaagcctc
    29341 tgttccagct gtcgttccga atacaaccac gcctgtcagc tcgttccctt ccagggcctt
    29401 atcgccgtgg agagcggttc ctatggcgtc tccggctgca tagagtccgg gaatctcgcc
    29461 gtcgtcaggc gtaactgcat tggcgcagct gtccacgttc aggcctgtgt tctttccgct
    29521 ctcgtccgtc acataggaaa cgcccagttc tcccagaaga tccaggtaag cgctgtctgt
    29581 cacgataagg gagcggcagg taagctcctg ctctttgccg gcgtctttta cctgaacgcc
    29641 tgtaacctcc ccgtcggcgc cgtagagcac cttagaaagc tctgcgtcct ctgccacggt
    29701 aacgttcagg ctgtcaaatt tctcctgaag cttcgtctga atctggcttc ccagctcctc
    29761 tccgccagcc gcctcatagc ttctggctgc gctggatcct tccttctgag tcacgccgga
    29821 aagctccacg cccagatcac gcacccagtc aagagccgcc cggctctcct cgcccagatg
    29881 ctctgccatc tcttcattgc cctttccgcc tccggctgcc agggtatctg cgatgtagct
    29941 gtccaccgta tcttcaattc cggcatcaga ctgctcctct gtatcggaag cgttcatgca
    30001 gcttcctgac agagtttttt cgctgctgcc cagcactaaa attttggccg gatcggttcc
    30061 ttctgccact gcctgaatcg ctgccgccat gccggccgga tcgccgcctg caatcacaag
    30121 atccgcgtct tccatgaaag ctgtctgctc tgcctgcgtg ctctcctcca cagcctcctg
    30181 ggaagcttcc gcctttgttg tctcttctgc tttatctcct gtactctggc tgctgcaccc
    30241 tgtcagggct cccactgcca gaactgctgc cgcccatgcg gccaatgatt tttttctcat
    30301 aaatgatgct cctctcccgg aagaaatctc ttccgtgcaa aataaaaaag ttcaatcgaa
    30361 cgttccttct tccgtgacag cattctatca caggaagcag gtcagatcaa ttgaactttt
    30421 attaaggttc tgttctaaat ccaaattttt tatgaatttt ttctgtactg gacttagaat
    30481 ccactttctt aacagcagag atccgcaatc acctgggcga aaatcttagc gcttaaaagc
    30541 agctcgtcaa tcacggcaaa ctcgtctgcg ccgtgcatcc ggttgtctgt ctccggaaga
    30601 gccgctccga aagccacgcc gttctttaag tcgtggacgt atgttccgcc tcccatggaa
    30661 acgcactctc ccttgcgtcc cgtgtactct tcataggcgc caagaagcgt ctttacaaac
    30721 ggagaattgc cgtctacgtg gtgaggcggc agcatttcct ttgtaagcac cgtaatgccg
    30781 tgctctgcca tcttttctgc caccggcttt aagacattgt cttcattgcc gcagataggc
    30841 gtccggctgt cgaaaattcc gtgcatccgg ctgtctgtga tctccagaat atcaaaggcc
    30901 agagtaagag cgcctgaaag ctcgtctgcc atggctactc ccagagcttt tccctctgtg
    30961 tctccatggg gaatcagctc tgtcagagaa cggattacct ccatctgtct gcaggctgca
    31021 aacggaagtc tcgtaatgag aagcaaaagc gcggtagccg cgttctttcc ctcctgggga
    31081 gtggaagcgt gggctccggc tccgcaggcc gtaatctcca gacatccgtc ctttcctacc
    31141 agctcaaagg aaactcccgt ctccttctcc acctggtttc ctgcctcgcg caccatatcg
    31201 tcgtccagcc cttcaaagac agcgtaggcc tttcctggaa ccacgttgac ctttgtgccg
    31261 gctgtgacag atttcactct tggaagcgcc tgggacggct caaactcagc ctcaaattcg
    31321 cagtttaaat ggcctttctc aatatttacc accggaaacg ctccgtctgg agaaaaggtc
    31381 atgggagctt ccttctccac tgcatagtaa tgggcgatat cgctgcttcc gcattcctcg
    31441 tccgttccca ggatcaggcg cacccgcttt tttaatggga tatttaattc ctttaccgcc
    31501 cgcatggcgt agagagccgc cacggccggt cccttgtcgt ctgctgttcc gcgtccgtag
    31561 agctttccgt cctgctccac cggttcaaat ggctttgtca ctgtccatcc ctctcccgcc
    31621 ggaaccacgt ccagatgggc caaaatatct aactggctct ccgttccgcc gaaatcaacc
    31681 gttcccacat aattgtcata gtttgaaatg gagaaaccgt agccctctgc catggacagg
    31741 gctgtctcca gggcgcggca ggctccctct ccatagggca tgccctcctg ataaggcatt
    31801 ttctcgctgt taatgcggca cagcgtctta atgtcctcca gcatttctcc cctgtgactg
    31861 tcaatatatt tctcgatctc ttctctgtac atccgatcct ctcctttccg gaaaccttcc
    31921 ctcagctgtt tcctctctct ttctttccca gagtctctat ttcagcattc ctgctaaaat
    31981 ctcgttgact gccttgccgt ctgcctttcc cttcaccttc ggcatcagaa tcttcataat
    32041 ggcgcccttg tcggacttct tcggctcctc gatgccaagc tcggccagca ctccggcgat
    32101 cacctggcgg atctgctcct ctgtcagatc agccggagca aactcctcgt atacggccag
    32161 tctggcagcc gcctcgctct taatatcctc tctgtctgca ggagcggttt ccatcgtctc
    32221 tttcgtctgc ttgatctcct tcttgacaat ggcgttctcc tcctcctctg tcagaggctc
    32281 cctcttgtca atctccgcgt tcttcagcgc ggacagcagc atggaaagag aatcctttct
    32341 cgccttgtcc ttggccttca tggcctccac catcgctttt ctcaccacat caattttgct
    32401 catgcgtcta cctcctgatg tttttatctt aatcccgtcc aaactcgctt aacacaagac
    32461 ctggatttct gtcgagaacc attccgacgc tccagctgtt gacgaataag agcagaggat
    32521 ttccctttaa gtccttaatt ctcttcatat cagaggttcc ctgaatctta gccggatcga
    32581 tctcctcctt attttcaatc cagcggatgt actcgtatgg aagcttctcc agcttgacat
    32641 ccacgttgta ctcattttcc agacggtagg tcagaacctc aaactgaagc tcgcctacca
    32701 cgcctacgat gatctcctcc attccagtat tgaactcctg gaaaatctgg attgcgccct
    32761 cctgggcaat ctggttgatt cccttgataa actgttttct cttcatggtg tccatctggc
    32821 gcactctggc gaaatgctcc ggcgcgaagg taggaattcc ctcgaactgc accttgtctc
    32881 ccggcgcgca gagagtgtct ccaatggaga aaatgcccgg atcgaagact ccgataatgt
    32941 ctccggcgta tgcctcctcc acaatctttc tgtcctgggc catcagctgc tggggctggg
    33001 acaggcggat ttttctgccg ccctgcacat gatttacctc catgcctgcc tcaaatttac
    33061 cggagcagat acgcataaag gcaattctgt ctctgtgggc tttattcatg ttggcctgaa
    33121 tcttgaatac aaaggcgctg aacttattgt taaacggatc tacctggcct tccgtagtct
    33181 ttcttggaag aggcggcgtc gtcattttca ggaagtgctc caaaaaggtc tccacgccga
    33241 agttagtcag agccgatccg aagaaggcag gagacagctt tcctgtgctg accttctcca
    33301 tatcaaactc ctcgctggca ccgtcaagca gctcgatgtc gtctaacagc tggctgtgat
    33361 aatcggctcc tacgacagaa tccacgtcgt ctgactccag atcaaattct ctggaagcca
    33421 cctccttctg accgcccata gcggctgtaa aggtagtgat tttcttcgta tttctgtcgt
    33481 aaacgccctt gaaattcttg ccgcagccaa tgggccagtt aatcgggcac gtcttaatgc
    33541 ccagaacgct ctcaatctca tccatcagct caaagggatc tctggcctcc cggtccatct
    33601 tgttgataaa ggtaaaaatc ggaatgttcc tcaggagaca tactttaaac agcttgatgg
    33661 tctgggcctc cacacctttg gaagcgtcga tgaccataac ggcggaatcg gccgccatca
    33721 gagtacggta ggtatcctct gagaagtcct ggtgtcccgg cgtgtccaga atgttgatgc
    33781 agtagccctc gtagttaaac tggagcacag aggaggtaac ggaaattcct ctctccttct
    33841 cgatctccat ccagtcggaa acagcgtgct tggtagcctt tctgcccttt accgtaccgg
    33901 ccaggttaat ggctcctccg tagagcagaa acttctctgt cagagtagtc tttcccgcat
    33961 ccgggtggga aataatcgca aaggtacgtc tctttttgat ctgttctgtt gtattttctg
    34021 tatttgccaa aatggtcttc ctccatattc tgtcgtgatt catttacatt ttcaggaaaa
    34081 aacagacacc tcttttcagg tgtccgtttt attctattat gaaatatatg gaaagtcaag
    34141 gccgtctcca gcgttccaga aaggcttccg ccagctctgc ccagggtttg cagcattctt
    34201 ccacatagct ccctcttccg tcggaggttt ccttgtccgt tctctcgtcg gccagagcca
    34261 ggccgtggcg tccctctgga aacaggtggg cctccgcgct gactcctgcc tttttaaggg
    34321 ccgacaaaaa gagcagcgaa ttttctgccg gaacggaggt atctgtgaag gtatgccaca
    34381 gaaaaaccgg tggaacgtgg cttcccacct gcttttccag ggacagcaga ttaagaaact
    34441 cctctctctc ctccccctca agctctccca acagcgcgtc aaaggagcct ctgtgggcgt
    34501 attctccaga ggtaatcaca ggatatccaa ggagcagccg atccggacgg atcaggagcg
    34561 aaatgtcggc cagactgctc tctgaaaaaa tcgtctcgtc tcttctgaaa ttgtctcctg
    34621 ccggaaactg cacctgccgc tttaccaggg cggacagaaa ttcctggttc cagaacactc
    34681 ccaggctggc cgccagatgg cctcctgcgg aaaatcccat gacagctacc tgttccggga
    34741 taatattcca ctctgcggcc ctcaggcgca ccatggccac tgcccccgcc agctcaagca
    34801 aagctgtggg aaagctgtcc ggcgcagtgc tgtagcggag cacaaaggtc tgatacccct
    34861 tggacagcag ctctaacgct accggctctc cctccctgaa cgagcagaat tcatagccgc
    34921 ctcccgggca gatcaccact gccggccgtt tctgaatcct gcactcctcc ccggaatcct
    34981 ggagataggc tgtcagctcc gccgtatgat ccgttttctt aaacgcgccg tttttctcta
    35041 tctgaatctg aatggtttca attctcacaa tctgcgtcct ccctctgtat ctttgcgcct
    35101 tattatagta catctttgcg tctgatacaa gcccgggccg cggcgggagc aggaagggcc
    35161 ataccggaag aatatacagg cccggcggta atgggaggct ttcgcagcaa atcgccggcc
    35221 tgcatattct tcactctccg tctgtcaagg ggcaaaattt tttaaatttc cctgctcccg
    35281 gtatattgtc cctgaaaaac ggaaagcctg atcatggaca aacaaagaag gaggctctct
    35341 ttatggcact gaataaagtt gaaatctgcg gcgtaaatac atcgaagctg cccctgctca
    35401 ccaacgagga aaaggaggag ctgttcgccc gaatcctgaa gggagacaag gaagccagag
    35461 aacagtatat taagggaaat ctccgcctgg ttctcagcgt catccagcgt ttttcaggca
    35521 gcagtgaaaa tgtggacgat ctgtttcaga ttggctgcat cggcctgatt aaagccattg
    35581 ataatttcga cattacccag aacgtccgct tctccaccta cgcggttccc atgattttag
    35641 gggaggtgaa gcggtatctt cgggacaata attccatccg cgtcagccgt tctctccggg
    35701 acactgccta caaagccatc tacgccaggg aaagcctgac aaagaaaaat ctgaaggaac
    35761 cgactctctg tgagatcgca gaagaaatcg gcgtcagcaa ggaacaggta acctatgccc
    35821 tggatgctat tcagagtccg gtcagcctct atgaaccagt ctacacagac ggaggcgatc
    35881 ctctctatgt catggatcag ctcagcgaca agaaaagctc ggaggaaaac tgggttgagg
    35941 atatttctct gaacgaggcc atgaaccgcc ttcctgagcg ggagcgccac atcatcgatc
    36001 tgcgtttttt tgaggggaaa acccagacag aggtggcgga ggaaatccat atcagccagg
    36061 cccaggtcag ccgcctggaa aaaaatgcct taaaggccat gcgtgcctac ctcagctgat
    36121 ccggtatttc ctgagagcgc acaggggatt ctgtctttca ggaggacatt caaacatgaa
    36181 aagagacgtt ttctgccaaa aatcagcgga acgcgtctct ttcttctggt tattcatatt
    36241 ttacaatctc ttttttcagc cgcttcatga tctttttctc cagtctggag atataagact
    36301 gggaaattcc cagcagatct gccacttcct tctgcgtcat ctcgtctccg tctgcgttgt
    36361 tgagtccgaa gcgcagctcc acgatggttc tctccctggg agtcagatgg ctgatggccg
    36421 tctttaagag atttctctct atctcatcct ccaaatcacg gtaaatcaca tcctcgtctg
    36481 tccccagaat gtcggaaagc agcagctcgt ttccatccca gtctacgttt aagggctcgt
    36541 cgatggaaac ctccagcttt gtcttgttat ttctcctcag atacattaaa atttcatttt
    36601 caatgcaccg ggacgcgtag gtagccagct tgatattttt ccctgtgttg aaggtgttga
    36661 tcgccttaat cagccctatg gttccaatgg aaatcagatc ctccactccc acgctggtat
    36721 tgtcaaattt ttttgctatg tacacaacca gcctcagatt gtgctcaatc aggctggatt
    36781 tggcctcccg atccctctcc gttcccagct ctcccagcac tctggcttct tccctgctgt
    36841 ccaggggagc cggcagaatg tccgttcctc caatgtagtg gatttcccct tctcccggca
    36901 ttaacagcgc ccggaaagta ggcaggtttt tcattcgaaa ccggctgggc gccgcggctt
    36961 tcatgatcat gattctctcc tcctgtttta tttctgctcg cctgtttttt tctgcaaagc
    37021 tctggagaaa gcgaaactgc ctgctcccag acctctgtgt gcagcaaaag tccatagctt
    37081 ccgtctggcg aaaggggcgt tttggagacg gcaatcagag gccgtttgaa atatctcttc
    37141 tggccgttta gttctattcg gattccgtcc gccgccgccg caggcagcat tccattctcc
    37201 ctccccacgc ttctgtaggg gatcagagac gtcccttctg tcccatcaaa cagtccgttc
    37261 agggctccct cccatattac gctgaccggg cggcggaaaa tcggatcgta cagctggttg
    37321 cctgtgtcta aaaatgcctt tacctgtatc tgtctccctt tgcagacgag aacggtttcc
    37381 gccctgcagc ttctgagccg tttctccctt cctgctgcct cccacagaaa acaggcagaa
    37441 aagcacacaa atcctgctcc ggacaggagc gctaaaaagg gaaggcagct ctgagccatc
    37501 cccttctgtc catctgatac aataccatag acagcccgtt ttaaaagcga cagacctcct
    37561 gacatcagag ccgacgtcag ataaagacct cccgcctgat gaagcaggct ctttggccgt
    37621 ctttcccggt aagccagata caccatgaga acgctgaccg ggccgaaggc aagcatcagc
    37681 tgaaatccct gttccgggac aacaaacgga ctgacgcagg cccacagcgc gcctgcggct
    37741 gctccagcgg caattcttcc ggcccgtatg ttaagtccca tcagctttcc cgtcattacc
    37801 agaagaaaac tgtctaacaa accgttttgg atcaatacca catccaggta cagtctgatt
    37861 tctgtctcca gctctgccac ccccctgtct gacagagtct attataaggg acagctccct
    37921 cagaatttgt caaacggcgg gggaaaatcc tgttttttca tcgtcaaa
//
LOCUS       DBMDUW010000023        36456 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_948_length_36456_cov_4.311539, whole genome shotgun sequence.
ACCESSION   DBMDUW010000023 DBMDUW010000000
VERSION     DBMDUW010000023.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 36456)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 36456)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36456
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_948_length_36456_cov_4.311539"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..662
                     /locus_tag="ACZPCR_06175"
     CDS             <1..662
                     /locus_tag="ACZPCR_06175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009262328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HIR1230497.1"
                     /translation="FNIRMPQPVNQKFLEVQDAYLQEEIEQHGITRIEDLQPIQQGIY
                     LWQGDITTLQCDAIVNAANSQMLGCFCPNHGCIDNAIHTFAGVQLRLACAELMKEQKH
                     EETTGSAKITPAFNLPCQYVIHTVGPIVGDCLTKQDEMLLSSCYRSCLELAEKNHIRH
                     IAFCCISTGEFRFSNGRAAEIAIQTVKEYKTQTHSRMEVIFNVFKEADYNIYRKLLQT
                     N"
     gene            607..1479
                     /locus_tag="ACZPCR_06180"
     CDS             607..1479
                     /locus_tag="ACZPCR_06180"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0017136 - histone deacetylase activity,
                     NAD-dependent [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family NAD-dependent protein deacylase"
                     /protein_id="HIR1230498.1"
                     /translation="MFLRKPIITSTESYSKQINRLKNEIGNADAIVIGAGAGMSASAG
                     FSYDGERFEKHFADFHQEYGITDMYSGGFYPYHSLEEYWAWWSRHIWINRYDVWVGKP
                     YTALLQLVKDKDYFILTTNVDHQFQLAGFDKKRLFYTQGDYGLWQCSKPCHDKTYDNE
                     ETVQQMVAEQKELKIPTELIPQCPVCGAPMAMNLRCDSTFVQDKGWYEAASRYDKFIR
                     RHKGKRILFLELGVGANTPAIIKYPFWQMTAQNAQATYACINYTEAVCPSQILKQSIC
                     IGADIGRVISEIVA"
     gene            1494..1667
                     /locus_tag="ACZPCR_06185"
     CDS             1494..1667
                     /locus_tag="ACZPCR_06185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016280883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HIR1230499.1"
                     /translation="MSKENWVLCPICGSKTRTKIREDTILAHFPLYCPKCKQETLIEA
                     KQLKISVVKEPDA"
     gene            2041..2493
                     /locus_tag="ACZPCR_06190"
     CDS             2041..2493
                     /locus_tag="ACZPCR_06190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016280390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1230500.1"
                     /translation="MIYSEQYKEHIEYTFAAFCKIVLRNAALSAYRDIGRRRKWEISL
                     DYLMEEKHYEPSTTDNYFDKQATKFVVCGEIIEIENERLAKAFSSLPELRQEILVLYY
                     FFHYTDKKIGETYGRSRTTANYWKLSSLKRLRKELERLEHEERKADTL"
     gene            2465..2668
                     /locus_tag="ACZPCR_06195"
     CDS             2465..2668
                     /locus_tag="ACZPCR_06195"
                     /inference="COORDINATES: protein motif:HMM:NF024059.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1230501.1"
                     /translation="MRNEKLIPFETIEKAVAGEPEAVNTVLLHYRGYIKHLSVFQGHY
                     NAEIQERMEAQLVRAILKFRFNK"
     gene            3636..5165
                     /locus_tag="ACZPCR_06200"
     CDS             3636..5165
                     /locus_tag="ACZPCR_06200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HIR1230502.1"
                     /translation="MRTVSEQEIISLAPNTGAVSNGRKISSSQRFVSRMRSADDTFYM
                     GECKGSGKSNYRVSADFVKEGAPVFRCSCPSRQFPCKHAVALLFEIEAGKDFPIGEIP
                     EDILEKRVKKEARERKAEQAAEEREGKSGIQDSGEEGSAGTEKKGGKSSKARSGSRSA
                     RTKKLKKQLEGLAMLGQLTDSLLTAGLASMGSISLKEYRELSKQLGDYYLPGPQAGLN
                     RLIFQMEKYQKIQDEACRKEAVRILIRLRALRKKGEAYLTNQLEQDSEETGSWLYEEL
                     GGIWRLDQLEKLGFKKENASLLQLAFSVRYDEAVKEYIDEGFWADIETGEVSVTRNYR
                     PLKALKYIKQEDSCFSLLKVPLLLYYPGEGNRRIRWDTASFAEPEDRDRKALMEKVQT
                     DFTAAVKQAKGQLKNTLSDDFCAILLAFSRIGRIPEEGKEGAWRYAAEDRAGNRIELR
                     DRKGEGWESCTAVLDMVSDSSLLQNQVLFGFLYYDEDDRSICLHPRSIVTEKEIVRLL
                     Y"
     gene            5184..7067
                     /locus_tag="ACZPCR_06205"
     CDS             5184..7067
                     /locus_tag="ACZPCR_06205"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230503.1"
                     /translation="MNLTALYELKEQLETAAVSGCRLMKEDFRLKRAIEQMKPLAAAA
                     PVFQKIEQTARLAVSSECGDPTGTLLDALALIDAVACTQGTVGVSGELQPLEGGEETD
                     GLRLLSNISYSRMAPLVEALTGTGGGRYAVIVKAMEEEPELFCDCRLAGLLVGALGDS
                     YRELASLAYRQLLKTGPGVLPLLKNGFDVAGKREMSLRLELIGKLAGRAETLLYRQAA
                     LEGDKQMKETAIPLLSLDQENVPFLFDMMKAEKGTVKNAVLKALSCMDMEDDSEYRKA
                     LKKKKAKEQAAILEESSHDRASDLTADLIEQELAAEQKQEKKRDLEERNALWRAAGGK
                     HSRRLLNLIRTLYQENPEEIPEWFFYDSLCDNPCQELYEFTEEMFEIWDKREPEKKER
                     SSGLLEAECAAKLITRPAAEVYEWFQSRPEEDTSGIFRALLGVRYASQSGQYVFSDWG
                     HGKGEEKKMIPLLEPLDGRWYDWLLTKTTRSRIRRANIKLRARTAYDRTAWDWKGWTK
                     LDTLLASLYCPEREGLAERYREYFGSLLQDGVGIERFHIDILSRCGYSDWDMAVDRIL
                     KNNKDRYLWGVRMLLDQIPLEGRALAECMKKSLSHGTATGQDRLLVWADQLMCGASVM
                     ELI"
     gene            7131..8225
                     /locus_tag="ACZPCR_06210"
     CDS             7131..8225
                     /locus_tag="ACZPCR_06210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015544324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1230504.1"
                     /translation="MGKKNDVQRLPAEALFQKEIDALIQAEQDPVPTGWNMSPRSVLT
                     YICGGKAGDMDISPKYIGNRRLVEIAISTLVTDRALLLIGEPGTAKSWLSEHLTAAIN
                     GDSTKVVQGTAGTTEEQIRYSWNYAMLIADGPSKEAMLKSPVYRAMETGTIARVEEIS
                     RCASEVQDALISILSEKRISVPELGIEVPAKKGFSLIATANTRDKGVNDMSAALKRRF
                     NIVVLPSPESLDAEMEIVRTRVAGLSENLDLNAALPDQEVVEKVCTIFRELRSGATLD
                     GKQKLKSTSGVLSTAEAISLLANSMALAGSFGNGRITDGDLAAALQGAVVKDEEKDAR
                     AWVEYLENIMKKKGSRWLGLYQECRDLNTI"
     gene            8271..10604
                     /locus_tag="ACZPCR_06215"
     CDS             8271..10604
                     /locus_tag="ACZPCR_06215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009215505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5682 family protein"
                     /protein_id="HIR1230505.1"
                     /translation="MERQWNSGMEQPDRPHLFGIRHLSPSGAWHLRKFLDETDPELVL
                     IEGPSDFTELLEDLTKKEVKPPVAVMAYTSDLPIRTILYPLAVYSPEYQAALWARDKG
                     KKARFFDLPSSVFLALEDQEKLSEENPGEKDKEGPESGDTGNTGDVYARLDQAAGTGG
                     NEDFWEHVLEHSETPKGYQMGAAVFGTELRRLSENTEGETDRENRLRERCMLREIKKA
                     VEEGIPASRIAAVTGAFHVAGLLEETPMTDEEFAALKRLPAHKTLMPYSYFRLSGLSG
                     YGAGNRAPAYYELLWEGRKRGQADYGAIQYLARLAAFQRKEGNPVSSAEVIEALRLAG
                     ALARLNGYENPSLQDLKDGAAACMGHGNIGELSVAMADTEIGTTMGSLPQGVSQTSVQ
                     ADFNRNLARLKLERFRSVTAQALDLDLREKLTVKSEQAAFLDLNRSFFLHRLRILHIS
                     FACLSDSRQTEATWKERWTLRWTPEAEMELVESVLKGDTVEQAASFELKSRADGAEEI
                     GKLSEIIREAFLCGMPEAVAYTVSALQAMAVDAVSAPELAQAAGALSFVIQYGDIRKL
                     DREPLIPVLKQLFLRLCLVLPGECRCDDEAADRLIPAMDTAARAAAAHDFLDGQRLER
                     TFREISERDDVNTRLSGFAGAILLEAGKMSETELSAEVSRRLSRGIPAELGAGWFEGL
                     SMKNHYGLIARLSLWKSLSGYLDTLDGEEFKRALVFLRRAFADFTSEEKNKIAENLGE
                     IWQVNPAAASAALNETLTAEETKELLEGLEDFDFDDI"
     gene            10645..11835
                     /locus_tag="ACZPCR_06220"
     CDS             10645..11835
                     /locus_tag="ACZPCR_06220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005540646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HIR1230506.1"
                     /translation="MDTMEQMRRWRLILGGESETQFETMNGYGEAGLSKEQLLMDQAL
                     AAIYNSSAYGGFGSPGNAGKGGGRGPSNPQITRWLGDVRTLFDRDLVKIIQADAMERC
                     GLKQLLFEPEVLENLEPDIGLASTILLLKDQIPKASKDSVREFIKKIVEQINQLLEQD
                     IRRAVTAAVNRRNHSPIPSASALDAAMTIRRGLKHYNPQLKKIVPEHFYFFDRTCRTA
                     AERYTVILDVDQSGSMGESVIYSSIMSCILASMAAVKTRIVAFDTNIVDLTDKCSDPV
                     DLLFGFQLGGGTDIDKSVAYCQQFIENPKKTLFFLVTDLEEGGNRASLLRRLEEIRQS
                     GASVICLLAISDRGKPCYDAQMAGRVAGLGIPCFACAPEKLPLLLERAFKGQDLSVFE
                     KQKE"
     gene            11982..12842
                     /locus_tag="ACZPCR_06225"
     CDS             11982..12842
                     /locus_tag="ACZPCR_06225"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0032775 - obsolete DNA methylation on
                     adenine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HIR1230507.1"
                     /translation="MTSSHTTGASARQELTPILKWVGGKRQLLDFIRPLIPEHTTYCE
                     PFVGGGAVFFDLQPKKAVINDFNQELINVYQTVKEQPEELIELLLRHREQNSQEYFYQ
                     IRALDREPEKYEELTPAQRAARIIYLNKTCYNGLFRVNSAGQFNAPWGRYKNPNIVPE
                     DNIRAMSRYLNKSKTTIRCGDYREALKGLRKGAFVYLDPPYMPLSSSSSFTGYTASGF
                     GQAEQIELKRQCDLLNKKGIKFLLSNSCCDFIEDLYSGYQIERVPAKRAINARADRRG
                     AIDEVLVRNF"
     gene            12853..14136
                     /locus_tag="ACZPCR_06230"
     CDS             12853..14136
                     /locus_tag="ACZPCR_06230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction enzyme"
                     /protein_id="HIR1230508.1"
                     /translation="MGMIEEKWNALFETYGIAEQVKRQGIFSITADQIREFKEPRLMT
                     KFDTRESVPTVFGKLGILPVTRGSYVIGDFSLYHDFPEEESRGGVIQVDRSRIPDYLE
                     TIDVRDVRSEAAAIKLISLTGILEDFLGEKRLVETVSGRMSSGAFDFQIHSGDRKHVS
                     RIQVNNSQLEIDGGFEGRDSFAILEGKNVVHSNFLVRQLYYPFRLWEGRLTKPVRPVF
                     LVCSNQIFRLLEYEFDDPMVYDSIRLVKEQRYSLEDTRITMEDLAGIMGSVPVKPEPE
                     GVPFIQADSFEKVISLIEHLGEKPLTMAEIAEIFGFQERQSGYYYNACAYLGLAVRKK
                     GRDGVVRAELTERGVSISRMDYKKRQLAYAGRILEHEIFHQLFETAVRTGKLPDKPYI
                     QRKMKELRLCGDSLIGRRASSVAGWLRWMVRLTEE"
     gene            14149..14763
                     /locus_tag="ACZPCR_06235"
     CDS             14149..14763
                     /locus_tag="ACZPCR_06235"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009254432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HIR1230509.1"
                     /translation="MDSKEARERMRAGRLYYESGSDLGEEQAKCLELLYDFNQTRPSE
                     DEKRQALLKEMFAEFGENCHIEPPLHANWAGKNVHFGDGVYANFNLTLVDDTDIFVGN
                     SVMFGPNAVVCTGNHPICPEIRRKQAQYNLPVHIGDNVWVGAGAIILPGISIGENSVI
                     GAGSVVTKDIPANVVAVGNPCRVIRPIGEEDRKYYNHGVEIDIE"
     gene            14831..16825
                     /locus_tag="ACZPCR_06240"
     CDS             14831..16825
                     /locus_tag="ACZPCR_06240"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230510.1"
                     /translation="MKKQRRRQMVSAALAGLCLVQASVLSGCSEKTKSPQAETDSQVH
                     TESGAAEQAGDKDRYLYYLKDNALYRADIKNPEKADPELLVDQVNKDEGEGISSSLDM
                     KWSEDGSYVLVPLYQEEEEGQYMRLYVIENRKGGKAERIAENASWYKLEGNTIVFNEK
                     SSKPDISPEALYCYRPEEGVFVISQQGGSNYPVLMTESCVCFSLQRTDFKENPVREDV
                     YYSDLTSKEASSPVLLGENVAYIEGMSGDGSKIWYTKEDKETDRLQLFLWEKGKDGKQ
                     LLDMDLANGYVASLSGETGEVYYMDRNPEDMASESGSLFDDMKVKQEKRENGQSGPRD
                     ALYYYKDGETVMLSEDVYDCAYGEEEGIFWYEEERADEEGAVVRYLVKDGQSWELKGV
                     PCDGCEYPQMYSPEEECCYLVCYDAEEDEEALYGWTYEYKLVKADMSDGHMGEMELID
                     TSLGEILLSRADDSQILYEKNINTENAEEFGNTELYLNGEKIAEDPLTYGKMNAGSED
                     IYVIAPYEDRNYQYLSYNYDNSGTLKRISEGQEETVSEEVTNVSAADDFLVMLTDYRN
                     PEFYGNLKLYQDGQTCLIDDHVESFYIRDIDRSLSAPSYYLQRDEETEESGDMSGMFP
                     DLFGQTEAQDDEEAATIEFPVEDEAYTGGLSAEETAEQQD"
     gene            complement(16889..17368)
                     /locus_tag="ACZPCR_06245"
     CDS             complement(16889..17368)
                     /locus_tag="ACZPCR_06245"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006782433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0043768 - S-ribosylhomocysteine lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HIR1230511.1"
                     /translation="MDKITSFTINHLELLPGVYVSRKDKADNAVITTFDIRMTRPNFE
                     PVMNTAEVHTIEHLAATFLRNHSLWKERVLYFGPMGCRTGFYLLLSGDYEARDIVPLM
                     KEMFAFIRDYQGEVPGACARDCGNYLDMNLPMANWLADRFLREVLDVIDDSHLIYPE"
     gene            17594..18598
                     /gene="trpS"
                     /locus_tag="ACZPCR_06250"
     CDS             17594..18598
                     /gene="trpS"
                     /locus_tag="ACZPCR_06250"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018596307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HIR1230512.1"
                     /translation="MLDGKKTLFSGMQATGNLTLGNYLGALKNWVTISDEYQTFFSVV
                     DMHSITVRQDPAELRRRARNLLTLYIAAGLDPEKNCIYYQSHVSGHAELSWILNCFTY
                     MGELNRMTQFKDKAAKHADNINAGLFTYPVLMAADILLYQADVVPVGIDQMQHLELTR
                     DIAIRFNNIYGDVFTVPEAYIGKAGAKIMSLQDSAKKMSKSDENPNGSIYLMDDPDTI
                     IRKFKRAVTDSEACVRYCDEQPGIKNLIDIYRACTGKTPQEVEKEFDGKGYGDFKMAV
                     GEAVVDVLRPLQERYAELSKDKAYIDSVIKNNAEKAQYFSNKTLRKVQKKVGFPEKIR
                     "
     gene            18874..19863
                     /gene="dhaK"
                     /locus_tag="ACZPCR_06255"
     CDS             18874..19863
                     /gene="dhaK"
                     /locus_tag="ACZPCR_06255"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004611211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HIR1230513.1"
                     /translation="MKKIINSVEQVENEMVLGMAKAYPQYVRKLDCGNVVVRANRKEG
                     KVALISGGGSGHEPAHGGYVGEGMLDAAVSGAVFTSPTPDQIYEGIKAVATDQGVLMV
                     IKNYTGDVMNFEMAGEMAQMEGIKVAQVVVNDDVAVKDSLYTVGRRGVAGTVFVHKIA
                     GAKAETGASLEEVQAVAQKVIDNVRTMGMAIRPCTVPAAGQPGFELNDDEMEVGIGIH
                     GEPGTHREPLKKADEIVDLLLEKILADLDYSGKEVAVMINGSGATPLMELFIVNNRVS
                     DVLAEKGVKVYKTLVGEYMTSIEMEGFSISLLRLDDELKELLDAKADTPAFKA"
     gene            19974..20597
                     /gene="dhaL"
                     /locus_tag="ACZPCR_06260"
     CDS             19974..20597
                     /gene="dhaL"
                     /locus_tag="ACZPCR_06260"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004611210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="HIR1230514.1"
                     /translation="MTDSAKIIELLDKIGDKIIEEKEFLTELDKPIGDCDHGINMARG
                     FGEVKKKLPGMADSDLGTIFKTTGMTLVSTVGGSAGPLYGTAFMKMGMALAGKKEMSF
                     NEFLTAFEAAVEGVKQRGKSDRSEKTMLDAMIPALEAMKAAAAEGKDAETAWKEGTEA
                     AEAGVEYTKTIIATKGRASYVGERSIGHQDPGATSFTFMMETVGAAL"
     gene            20625..21005
                     /gene="dhaM"
                     /locus_tag="ACZPCR_06265"
     CDS             20625..21005
                     /gene="dhaM"
                     /locus_tag="ACZPCR_06265"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HIR1230515.1"
                     /translation="MVGIVIVSHSKNLADSVVEFTGLMAPDAKIAAAGGMEDGGFGTS
                     FEKIQKAIESVYSEEGVIVLMDMGSAVMTTEMVLDMFEPDTVKMADCPLVEGAVVATI
                     NAVSGMKMDEILAALSQVAGTPKF"
     gene            21034..21822
                     /locus_tag="ACZPCR_06270"
     CDS             21034..21822
                     /locus_tag="ACZPCR_06270"
                     /inference="COORDINATES: protein motif:HMM:NF042666.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6612 family protein"
                     /protein_id="HIR1230516.1"
                     /translation="MRRWRKAAAVLMAGALAVAAVSGCAKKQDPKEIYSAAMEKNSAL
                     DSVDMDVTMKMAMTADEESMDMEVSSNTKMDQSDKEHVKFITASSVAMDGMNMETTVF
                     YEDGYYYMEAMGQKMKYPMDLESLTAQIQESVGSTTLPVESLDTVEVKKDGDNQILTF
                     TANPEKMNDYLGQVMGAMGDVSQVSGLNMTINSADGEYTIGKDGYYTDMKMNLDLSME
                     SQGASVGMILDITGTVHQPGQPVEITLPDTADYVEIDPALLGAS"
     gene            complement(21950..22180)
                     /locus_tag="ACZPCR_06275"
     CDS             complement(21950..22180)
                     /locus_tag="ACZPCR_06275"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230517.1"
                     /translation="MNIQKFLDSKHGNILGRVYFLILLFFGNGLIPIGAVIKFLHNGS
                     GVLMIAGLLITVIAIAILSTPYDLSNYKETEE"
     gene            complement(22180..23526)
                     /locus_tag="ACZPCR_06280"
     CDS             complement(22180..23526)
                     /locus_tag="ACZPCR_06280"
                     /inference="COORDINATES: protein motif:HMM:NF013715.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HIR1230518.1"
                     /translation="MNQTETNPRYSENALREKAFLSELNKKPPLQKFFGYCKLSGPGF
                     MNAAFTLGAGSFASSVTLGAAYGYDMLWIPLYSFALGLFMLALSTRFVTASEISVIKA
                     QDKFHGKFFGSLATGLIACFIASIVYNFGQYALGADAVTALFSIVNINVPKNISWILL
                     VAVSVPLSLMYGSGNNPKGVRIVENAMKILIGIMLVVFGAVLCVTGIDMPAMIKGLLI
                     PTLPSGIDGIVMLIASLTATIGVMDWVLFNNGMESRGYSENHETLGRFDAVFGGLVPV
                     TLVLSFVSIAFAEAFAGKEGIPTDSTELCSALVSVIPSIWIQIGFYIGIIALVCSSMI
                     GLSVTCATSFYQSTNVKKDTNAWYHPFIVLAPQIGFLGAFFGKPVMVVVFIAAMQSLF
                     NWISGNSWYLLGNDPRYLGKKVIQSRFFNAGILACISVLNIVFITFIMSKMGVWPS"
     gene            complement(23561..24040)
                     /locus_tag="ACZPCR_06285"
     CDS             complement(23561..24040)
                     /locus_tag="ACZPCR_06285"
                     /inference="COORDINATES: protein motif:HMM:NF025559.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HIR1230519.1"
                     /translation="MYNPNDPVGKVTETMAKLFAVMADEIIREMGNEKGEAAVRRAVR
                     RFANLRADAIKERIRKDGKEVTFHTVEEYSDYPDNQAWDCESSVEGNQLREINRVCPF
                     STAFREIGLEQAGKLYCEEIDLALNEAFFGKIKFERPSLFTDGPCAPCEMIVTRLDK"
     gene            complement(24225..26012)
                     /locus_tag="ACZPCR_06290"
     CDS             complement(24225..26012)
                     /locus_tag="ACZPCR_06290"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: protein motif:HMM:NF025854.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1230520.1"
                     /translation="MANRIYRIFWVFFLAVSGVFLLSLQNERPTDSYHVFLDLTKSNG
                     AVHFESSEAEEDTLSFCCPLPSVQAAQPTLAVSGQLPSEIWADGRKIPVPDSCETFAL
                     DSETWFLIPLSQKEESSFSRLRLQFEPLQTAPSLLFRESCGEYILSETPRICFGSRNA
                     LLSNLAMSGSLHIVAAAVLFFVAFVILAAGFVFQYVYKIQTYIFSIGFCFFGYGIWIL
                     CESSLALSVLDGFSIDMIKCVSIFIIPVLLYRYIRLKFPRVYPGIFTFLYLFHFVVLL
                     SAVLAMMAGSLPFYRLEQSLWFLFICTLIVCICFLSAEVSENKPLHTVYIGILIIFFT
                     FFIYLLFYNFQPMVAIRSLVIGSVCLILYNFSIFVPETARIYRQSLERKSLEQQLNEQ
                     VRHYRQMETRDEQFRRLHHDMKHHWQTVQTLLSEGKSREVLDYVARIQEQLSPPARRC
                     IINTGNSFLDAVLTSKLEQASEADIQTDTEIMVIKNMNIDMADCSIIFGNILDNAIEA
                     CRLIRSPEQRRISVKLLYKKNMLVCGFSNSMSQDVPVRAGFPTTKPSPEQHGLGLSNV
                     REAAAKYGGNLNIRAEQGRFEVSFVLFGV"
     gene            complement(26026..26757)
                     /locus_tag="ACZPCR_06295"
     CDS             complement(26026..26757)
                     /locus_tag="ACZPCR_06295"
                     /inference="COORDINATES: protein motif:HMM:NF012301.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HIR1230521.1"
                     /translation="MIHICVCDDDDAMGSRLSGLIQDVCKKHGICASVCRFSSGEELL
                     FHLEEMKQPIDIYFLDILMKQLNGVETAARLRAVSPTAQIIFLTVSKEHVFEALDVMP
                     LHYLLKQDVGTGKIETVLLRAVSLAEKSQRQSFTYKFGKTIGSVLLRDIVYFEVKNRI
                     IEIHLKNGPAIEFYGNIKDLEQQLLSASFERVHRSYIVNFENVDYLQGREFVCVDQTV
                     IPIGQKYAGAVEQYQNYLLNGLSMI"
     gene            27001..27858
                     /locus_tag="ACZPCR_06300"
     CDS             27001..27858
                     /locus_tag="ACZPCR_06300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003022952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HIR1230522.1"
                     /translation="MKIAVAYDNGNVFQHFGKTEYFKVYETENNQVVSSEVISSNGEG
                     HGALAGVLAAQSVNVLICGGLGGGAQTALDEAGIQVFSGAQGSCDEAVEAYLKGELVS
                     TGVNCDHHDHEEHEEGHSCGGCGGGCSGCGGGCGSQPQIIMEGRNAGKLCRAHYRGTL
                     NDGTQFDSSYDRGQPLEFICGVGQMIKGFDAAVVNMEPGQSVDVHLMPEEAYGMPDPD
                     AIFTVEIAQLPGAENLEVGQQVYLSNQFGQPFPVKVTAKDETNITFDANHDMAGKELN
                     FHIELLETE"
     gene            28117..29199
                     /locus_tag="ACZPCR_06305"
     CDS             28117..29199
                     /locus_tag="ACZPCR_06305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007038288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1230523.1"
                     /translation="MSEHVQAVMEHNSELEQLGNLTRRELKELEEKEKTPVQKVEEAL
                     IMALPAVCGAAALSEYLLIPDLARNKNPMYYVYVLAAMMAAYLCAGLFAAFKRRRGNK
                     VYYEKLRYGAPRISALFLLLALYDYLTLKTGTLTQPFVPCMNFIINAFVSDYPMLIEC
                     TMHTLRLLMIGYVIGVSLGLVTGITCGYSRRVRYWVDPVIKFLGPIPTSTWIPVIMVI
                     ASSLFAGAVFIIALGSWFAVTVASLTGISNVDKDFFEAARTLGASKRQLVFRVAIPHA
                     MPSILQGCTQAMSSSCVALMIAEMLGVKAGLGWYMTWQTGWASYDKVFAALFVICLIF
                     TLVTKALEAVKHHVLRWQNGVESNGR"
     gene            29174..29962
                     /locus_tag="ACZPCR_06310"
     CDS             29174..29962
                     /locus_tag="ACZPCR_06310"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1230524.1"
                     /translation="MELKVMEDKKVTLKLENVSKVFAKVESDDVTHALYNVNVQMESG
                     EFISLVGPSGCGKSTILRLVAGLITPTLGTVSVNGAVVEGPDPNRGMVFQKPTLFPWL
                     TVEKNIAFSLEMQGKLKGNEEKVQRMLNIIGLEQFKDDYPGQLSGGMAQRVALVRSLI
                     NEPDILLLDEPLGALDAFTRMNMQDEILNMWADTRQLALMVTHDVDEAIYMGTRVLVM
                     DANPGRIVAEIKIDGAFPRDRSSAQFVEYRNEILNQLHYGGKRG"
     gene            30026..31258
                     /locus_tag="ACZPCR_06315"
     CDS             30026..31258
                     /locus_tag="ACZPCR_06315"
                     /inference="COORDINATES: protein motif:HMM:NF020650.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIR1230525.1"
                     /translation="MKKKQIAASLLALTVACSMTACSGKPEEAADTTAAAAEQGEIAG
                     DTNNDGQIDMGVDENVEVKQENASEHMDSFEASTSGKWEAMFTPVDMEGRAIDMADFD
                     LTPTEEELEAMKKEPAYGQKVLYYMADGCTAGPTVAAHLGYYEEAGLEAEGVKGNSYT
                     EALGSGQATVAVGHIATMLVPITNNVDITFVGGAHIGCKSLYVLADSEYNTTEDLKGT
                     NISAPNGIGKSDYNITCLLLDADGINPQEDVNITAVSADACLTAMTNGEISAALLSDT
                     FAYGLVKDGTLKCVRSLLDEDFADENCCMIAMNRTFVKENPVISKKITQAVQKAHSYM
                     RDNPEEATQMLLDQGWNGGSYEMNVMLNNSLQFGLDQDFTEVSLRDVVEKYVRLGLIQ
                     NMDDTDEIMSIAWTPVLD"
     gene            31361..31897
                     /locus_tag="ACZPCR_06320"
     CDS             31361..31897
                     /locus_tag="ACZPCR_06320"
                     /inference="COORDINATES: protein motif:HMM:NF025745.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4418 family protein"
                     /protein_id="HIR1230526.1"
                     /translation="MSGEFPSRLAVGIFPVHGEIGYESEEKERMMVGSNETNRRKQEK
                     NSLIFAAAQAVHALLLILAVKVFAPVCTGMVDTAAGKQVPMRCHYTAVLLLFLGLILL
                     VNAGLCAVRREMAVCGTITAVLSALAFAALSSSMGTGICLNPEMACHVTASFVKALGG
                     IGILIGVLCTYMGVKAGK"
     gene            31920..33146
                     /locus_tag="ACZPCR_06325"
     CDS             31920..33146
                     /locus_tag="ACZPCR_06325"
                     /inference="COORDINATES: protein motif:HMM:NF024116.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1230527.1"
                     /translation="MKRDKKLSALNMAVQNLKAKKSRTLFMMFFVVLMAATVFFSTIL
                     MDNMRRGIKSTTERAGADIIVVPDEGTEDIRDSLFAGKPCSVFFDRSMKEAVEQVEGV
                     ERVSGQMYVGTLSASCCSLPVQMIAFDPETDFVVQPWLKNQNAVRLEKGQVLVGSSVV
                     AEPGETLQFYSTDFQVAGKLERTGMGYDSSVFMTFESLYELKNSETAMNNLPMEDIEN
                     KLSMLMVDIRDDIKDLDLIHLRLDIAKCGPEGEKMYAGSTDELLSGVSSQVKKLSGYG
                     NILTYISILSAALALISIFVITINERKYEFGVLYALGAKKSHMRNIILAEALMISGAG
                     GILGVLAAYGLTAAFADVIRVQLDIPYLNMSLAEAAPVAGLCIGLALLTGIAAAVCSA
                     YQISKGEVYRLLRENE"
     gene            33147..33806
                     /locus_tag="ACZPCR_06330"
     CDS             33147..33806
                     /locus_tag="ACZPCR_06330"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: protein motif:HMM:NF012235.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1230528.1"
                     /translation="MIQVEHVTKQFTRNDRDFDAVHDVSLEVKKGEFAAITGHSGSGK
                     TTLFNMMAGLTAPLSGKIYIGGSEITGMKENEKAVFRSQNMGYVLQGQSLLNNFTILD
                     NICMPAYLSSQVKEFKERALELLRQIGLEEFAGEYPANLSGGEIRRVAIVRAMLNQPK
                     VILADEPTSNLDPENSHKVMQMLKDISRSGTTVVLSTHELEYLSYVDRVFNMNRGKME
                     E"
     gene            33990..35168
                     /locus_tag="ACZPCR_06335"
     CDS             33990..35168
                     /locus_tag="ACZPCR_06335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005604278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease domain-containing protein"
                     /protein_id="HIR1230529.1"
                     /translation="MAESDFQKAESQLQIDAEYYNTLDIGGFSRMLKDPSYCYKFYWL
                     EAIVKLISEDRQEVSYDEMINEMISNAWYSVLEFHVHLSGIWGDGEIKDSLEKAVLKL
                     YRLSGLPANASKVEIKNKIAEFDKELHEEKMVLTKNVPYKALSGFANRSSEYIDLNSS
                     AGRMIAYYNRLNSRGTLLLYTFDSQKGLERKIIFQEAWIQMIQDQMTAILGWIQYEKV
                     RWLQNNNPEVPGLVYKLMPLDDKMRKLAHVRRLWEGILDTTSITDVFKHEPIKKESYD
                     VDHFIPWSFVMNDELWNLMPMDSSLNSSKSNRLPQWDRFFARFAENQYIMYELIHGKA
                     RIRKLYEACYRDNLHSIWASQELYRKGNTRKEFFSILEKNMRPVYDSARRQGYEVWRV
                     "
     gene            35702..36319
                     /gene="fic"
                     /locus_tag="ACZPCR_06340"
     CDS             35702..36319
                     /gene="fic"
                     /locus_tag="ACZPCR_06340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005947501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0070733 - AMPylase activity [Evidence
                     IEA];
                     GO_process: GO:0018117 - protein adenylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="HIR1230530.1"
                     /translation="MLENKLGITDSTELARAEEKISKQKAVEMFENGFFETLESGTYK
                     SLAMIHQYLFDEIYDFAGKLRKVNISKGNFRFAPLMYLEAALQSIDKMPQSTFDEIVE
                     KYVEMNVAHPFREGNGRSTRIWLDLMLKKEIGCVVDWSKVGKEDYLLAMERSPIKDIE
                     IKFLLKNALTDDVNNREIYMKGIDHSYYYEGYYVFKTEDLTGTKE"
     gene            36354..>36456
                     /locus_tag="ACZPCR_06345"
     CDS             36354..>36456
                     /locus_tag="ACZPCR_06345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein Fic"
                     /protein_id="HIR1230531.1"
                     /translation="MQYLSAAKITEKWNISERSVRNYCAHNRVEGAFI"
BASE COUNT         9987 a         7709 c        10550 g         8210 t
ORIGIN      
        1 tttttaatat tcgtatgccg caacctgtaa atcaaaagtt tttagaagta caggacgcat
       61 atttgcaaga agaaatagag cagcatggaa ttacacgtat tgaagattta caaccaatac
      121 aacaagggat ttatctatgg cagggagata ttactacact ccaatgcgac gctattgtaa
      181 atgccgccaa cagtcaaatg ctcggttgtt tctgtcctaa tcatggttgt attgacaatg
      241 ccattcatac ctttgcaggt gttcagcttc gcttggcttg tgcagagcta atgaaagagc
      301 aaaagcatga agaaaccaca ggcagcgcaa aaatcactcc ggctttcaat ctgccttgcc
      361 agtatgtcat tcatacagtc ggaccgattg ttggagattg cttgacaaag caagatgaaa
      421 tgttactttc ttcctgttat cgttcctgtc tggaactggc agagaaaaac cacataaggc
      481 acatagcatt ttgttgtatc tctacgggag aatttcgctt ttcaaacggc agagcggcag
      541 aaatcgcaat tcagacagtt aaagaataca aaacacagac acatagcaga atggaggtaa
      601 tttttaatgt ttttaaggaa gccgattata acatctaccg aaagttactc caaacaaatt
      661 aacagactga aaaacgagat aggaaatgcc gacgctattg tgattggagc aggggcggga
      721 atgtctgctt cggcgggatt ttcttatgac ggagaacggt ttgaaaaaca ctttgccgac
      781 tttcatcaag agtacggtat taccgatatg tattccggcg gcttttatcc ctatcattct
      841 cttgaagaat attgggcttg gtggtcaagg catatttgga taaaccgata tgacgtatgg
      901 gtgggaaaac cttatactgc attattgcag ctcgtgaaag acaaagatta ttttatcttg
      961 acaaccaatg tagaccacca atttcagctt gcgggatttg ataaaaagcg gctgttttat
     1021 acgcagggcg attatgggct ttggcagtgt tctaaaccct gtcatgataa aacctatgat
     1081 aacgaggaaa cggtgcagca aatggtggca gaacaaaaag aattgaaaat tccaacagaa
     1141 ctgatacccc aatgtcccgt atgcggtgcg cctatggcaa tgaatttacg gtgtgatagt
     1201 acctttgtgc aggataaagg ttggtatgaa gcagcgagcc gttatgataa gtttatcaga
     1261 cggcataaag gtaagcgtat tttattttta gaacttggag ttggggcaaa cacgcccgcc
     1321 attatcaaat atccattttg gcaaatgacg gctcagaacg cacaggctac ttatgcttgt
     1381 attaactata ccgaggcggt ttgtccgtcg caaatactaa aacagtcaat ttgtataggc
     1441 gctgatattg gacgtgtaat ttcagaaatt gtcgcttagg ggggagaaaa aaattgagta
     1501 aggaaaattg ggtgctttgt ccgatatgcg gcagtaagac gaggacaaaa ataagagaag
     1561 atacgattct tgctcatttt cctctttact gtccaaagtg caaacaagaa actttgattg
     1621 aagcaaagca attaaaaata tccgttgtca aagagccgga cgcatagacg cagagccgat
     1681 aacacataag gttttttcct tgtggttatc ggcttaattt ttttgaaata accgccgttt
     1741 tcctttttca aaacgtgaat acggagggcg tattaaattt gcctattttt aaggatatgg
     1801 cggtatcaaa tgcttaacgc attgggaggt atcgttatgt cctttttcta cgtccttaat
     1861 cattatctat catcaaaaaa agtctgtttc ctgtaagggg attttgcggc tatgaagatg
     1921 aacagacaaa tcatattgat tgcttaaata attcatatta cctaaatgcc tatgccgctt
     1981 tatgctgcgt aggcgtttgt tgtaatagcc ccctactggg aagaaagggg gtgatttcag
     2041 atgatttatt cagagcaata caaggagcat atcgaataca cctttgcagc cttttgcaaa
     2101 atcgttctcc gcaatgccgc cctgtctgct tatcgggata ttggcaggcg gcgaaagtgg
     2161 gaaatttccc ttgattatct catggaagaa aagcactatg agccgtctac aacagacaat
     2221 tactttgata aacaggcaac aaaatttgtt gtatgcggcg agataatcga aattgagaat
     2281 gaacgattag caaaggcatt ttccagtctg ccagaactgc gacaggagat tttggtgttg
     2341 tattactttt tccactatac cgacaagaag attggcgaaa catacggaag aagccgtaca
     2401 actgcaaact actggaaatt atcgtcactt aagagattaa gaaaagaatt ggagagattg
     2461 gagcatgagg aacgaaaagc tgataccctt tgaaacgatt gaaaaagcgg ttgccggaga
     2521 gccggaagcg gtaaatactg tcttattgca ttaccgaggg tacatcaaac atctgtctgt
     2581 atttcaaggg cattataacg ctgaaattca ggagagaatg gaagcacagc ttgtaagggc
     2641 aatcctaaaa tttcgtttca acaagtaacg aatagcaaag ccagaaacag ccgtcaagga
     2701 taaacgttgc gctgaaagcg tccttgacgg ctgttactat ctttgcttgt gggtagtcaa
     2761 gagagcgcaa tcggataaac cgcttacgct ctcaaatcat tatggagaat gtcacgcagt
     2821 aggcggtctg aaagccttga ttttgtggct ttgtgagcac aaaataaagg agggcaaggg
     2881 ttttatactc atacccccga aaatagcgtt ctattgcgta acaaaacagg tagcctgttt
     2941 acgctcccta tggttttcta aacggataat gattgctgtc tttccgtttc ttttcgcttc
     3001 tattccgaca gcttgcgagt agagagaaaa ttggtggaac ggaaaggaat ggaatgggta
     3061 attgatttaa tccgtaatta ttttatcttt actttatata tctttattta attatccggt
     3121 atcggaaaat ccaacatcgg gtaatccaac atcggaagcg gaaactgcaa catagtttta
     3181 ttccatgcga acagctacat gaattgccgt aggaatgtta cgtagtaggg gcttaaaaag
     3241 ccttgattta tacggcttac agacacgaaa atatcaagga taagggtttt ataccttttc
     3301 cctcaaaagt ggcgttctac tgcgtaacgg gatataaaaa cagcgtgtac cgtttcttac
     3361 agtacacgcc gctttgttgc aaccctgttt gtcagccgtt aagttaattt tcttgtgata
     3421 cttccttatc ggcgttcatc taaggcgtat gccttctttt tttattgcag gaacattttt
     3481 gggaatcccg gtctttggat gggatatttg aaaaactctc cagagccagg cgcttggcag
     3541 acagacttga attgacgaaa aattaagaaa atagtcgaag attttttgac tgcactatgg
     3601 tatgataaat aaaaattcta cagataggag gccatatgag aacagtcagt gaacaggaaa
     3661 tcatcagcct ggctcccaat acgggggctg tatccaatgg aagaaaaatc tcttccagcc
     3721 agagatttgt gtccagaatg cgatctgcag atgatacctt ctacatgggg gaatgtaagg
     3781 gaagcggaaa atcgaattac agagtgtcgg ccgactttgt gaaggaggga gcgccagtct
     3841 tccggtgtag ctgccccagc cggcagtttc catgcaagca cgcggttgct ctgctgtttg
     3901 agatagaggc ggggaaggat tttcccatag gagagattcc ggaggatatt ctggaaaaga
     3961 gagtgaaaaa ggaagccaga gagaggaagg cggagcaggc cgctgaagag agggaaggaa
     4021 aatcagggat tcaggattcc ggggaagaag gttctgccgg gacggagaaa aagggcggca
     4081 agtcttccaa agccagatca ggatccagga gcgccagaac gaaaaagctg aaaaagcagc
     4141 tggaagggct ggccatgctg ggacagctga cagattctct tcttacagcc ggactggcgt
     4201 ccatgggaag catttccctt aaagagtaca gagagctgtc taagcagctg ggagattact
     4261 atctgcccgg tcctcaggcg gggctgaacc gtctgatttt ccagatggag aagtatcaga
     4321 agatccagga tgaggcctgc cggaaggagg ctgtccgcat tctgatccgt ctgcgggcgc
     4381 tgagaaagaa aggggaggct tatttgacga atcagctgga acaggattct gaggagacag
     4441 gaagctggct ttacgaggag ctgggaggaa tctggcgtct ggatcagttg gagaagctgg
     4501 gattcaaaaa agagaacgcc tctcttttgc agctggcctt ttcagtccgg tacgacgagg
     4561 cggtgaaaga gtatattgac gagggcttct gggcggatat cgagacaggc gaggtgtcgg
     4621 tgacgagaaa ttacaggccg ttaaaggcgc ttaaatacat taagcaggag gattcctgtt
     4681 tttcccttct gaaggttccg cttcttctgt attatccggg agagggaaac agaaggatcc
     4741 gctgggacac ggcttctttt gccgaaccgg aggacagaga cagaaaagct ctgatggaga
     4801 aggtccagac agattttacg gcggcggtga agcaggccaa gggtcagtta aaaaatacgc
     4861 tgtccgacga tttctgcgcc attcttctgg ccttttcaag gattggccgc atcccggaag
     4921 agggaaagga aggcgcgtgg cgttatgcgg cggaagacag ggctggaaac agaattgagc
     4981 tgcgggatcg aaagggagag ggctgggagt cgtgcacagc tgtgctggat atggtttctg
     5041 attcatctct tctgcaaaat caggttttgt ttggttttct ctactatgac gaggacgacc
     5101 gaagcatctg cctccatcca agaagcattg tgacagagaa agagattgtg aggcttctgt
     5161 attaggaaaa aggagggatg aatatgaatc tgacggcttt atatgaactg aaggaacagc
     5221 tggagactgc cgcagtcagc gggtgcaggc tgatgaagga ggatttccgg ctgaagaggg
     5281 cgattgagca gatgaaaccg ttagctgccg cggcccctgt atttcaaaag attgagcaga
     5341 cggccaggct ggcagtttcc tcagagtgcg gtgatccgac tggaacgctt ttagatgctc
     5401 tggccctgat tgacgcggtg gcctgcactc agggaaccgt gggagtgtcc ggagaactgc
     5461 agcccctgga aggcggggag gaaacggacg gactccgcct gttaagcaat atttcctaca
     5521 gccgtatggc tcctctggtg gaagctctca cgggaacggg gggcggacgg tatgccgtca
     5581 tagtgaaggc catggaggag gagccggagc tgttttgtga ctgccgcctg gcaggacttc
     5641 tggtgggcgc cctgggggac agctaccggg agctggccag cctggcttac aggcagctgc
     5701 tgaaaacagg ccccggcgtt ctgcctcttt taaagaacgg cttcgatgtg gcgggaaaga
     5761 gggaaatgtc tctccggctg gaactgattg gaaagctggc aggcagagcg gaaacgcttc
     5821 tgtaccgcca ggcagctctg gaaggggaca agcagatgaa agagactgcc attccacttc
     5881 tcagcttgga tcaggaaaac gtgccgtttc ttttcgatat gatgaaagcg gagaagggga
     5941 ctgtaaaaaa cgctgtgctg aaagcgctgt catgtatgga tatggaggat gattctgaat
     6001 acagaaaggc gctgaaaaag aaaaaggcga aggagcaggc ggctattctg gaggaatcca
     6061 gtcatgacag agcttccgat ctgacggctg atttaatcga acaggagctg gctgcagagc
     6121 agaaacagga gaaaaagcgg gatttggagg agcggaacgc tctctggaga gcggcgggag
     6181 gcaagcattc cagaaggctt ttaaatttga ttcggacgct ttaccaggaa aatccggagg
     6241 aaattccaga atggtttttc tacgattctc tctgcgacaa cccatgtcag gagctttatg
     6301 agtttacaga ggaaatgttt gaaatctggg ataaaagaga gccggaaaag aaggaaagga
     6361 gttcaggcct tctggaggct gagtgcgcgg caaagctgat tacaaggccg gcggcggagg
     6421 tttatgagtg gtttcagtcc aggccagagg aggatacgtc cggcattttc cgggctcttt
     6481 tgggcgtcag gtatgccagc cagagcgggc agtacgtttt ctcagactgg ggccatggaa
     6541 agggggagga gaagaaaatg atccccctgt tggagcctct ggacggcaga tggtacgact
     6601 ggcttctcac caagacgacc agaagcagaa tcaggagagc caatattaag ctccgcgcga
     6661 gaacggccta tgacagaacg gcctgggact ggaagggatg gacaaagctt gatactcttt
     6721 tggcctctct gtactgcccg gagcgggagg gcctggctga gagataccgg gaatatttcg
     6781 gaagccttct gcaggacgga gtgggaatcg agcgtttcca tattgatata ttgagccgct
     6841 gcggctattc agactgggat atggcggtgg accggatctt aaaaaataat aaggatcggt
     6901 atctctgggg cgtgcggatg ctccttgacc agattccgct ggaaggaaga gcgctggcgg
     6961 aatgtatgaa aaaatctctt tcccacggaa cggccacagg ccaggatcgg cttctcgtat
     7021 gggcggatca gctgatgtgc ggcgcgtccg tgatggaatt gatatagccg cagaaaaaga
     7081 aaagagagaa gataagaagg caggaaaaaa gagggaaagg cggaaacagg atgggaaaga
     7141 aaaacgatgt gcagagactt ccggcggagg ctctgtttca gaaggagata gacgcgttaa
     7201 tccaggcgga acaggatccg gtgccaaccg ggtggaatat gtcgccccga tcggtgctga
     7261 cctacatatg cggaggaaag gcgggggaca tggatatttc ccccaaatat atcggaaaca
     7321 gaaggctggt ggagattgcc atttcgactc tggtgacaga ccgggcgctg cttctgatcg
     7381 gggagccggg aacggcgaag tcgtggctgt cagagcatct gactgccgcc attaatgggg
     7441 attccaccaa ggtggtgcag ggaacggcgg gaacgacgga ggagcagatc cgctattcct
     7501 ggaattacgc catgctgatt gcagacggcc catcgaagga ggccatgctg aaaagccccg
     7561 tttaccgggc catggagacg ggaaccatcg ccagggtaga ggagatttcc agatgcgcct
     7621 ccgaggtaca ggacgcgctg atttccattt tgtcagagaa gcgcatctct gtgccggagc
     7681 tgggaatcga ggttccggct aaaaagggat tttctctgat tgccacggct aatacaaggg
     7741 ataagggcgt caacgatatg tccgccgctc tgaagcggag atttaacatc gtggtgcttc
     7801 cgtcaccgga aagcctggat gcagagatgg agattgtgag aaccagagtg gcaggccttt
     7861 ctgaaaatct ggatttgaac gcagctctgc cggatcagga ggtggtggag aaggtctgca
     7921 cgattttcag ggaactgcgt tccggcgcga ctttagatgg aaagcagaag ctgaaaagca
     7981 cctccggcgt gctgtccaca gcggaggcaa tttctcttct ggcaaacagc atggcgcttg
     8041 caggcagctt cggaaacgga cggatcacag acggggatct ggcggcagct ttacagggag
     8101 ctgtggtcaa ggacgaggag aaggacgcca gggcctgggt ggaatatctg gaaaacatta
     8161 tgaagaagaa aggatccagg tggctgggac tttaccagga gtgccgggac ctcaatacaa
     8221 tttagcggcg ggatacaagg ggtatcgtgc ccctcagcgg gaggaatgaa atggagagac
     8281 aatggaacag cggcatggaa cagccggatc ggcctcatct gtttggaatc cgccacctgt
     8341 cgccttcagg agcctggcat ttgagaaaat ttctggatga gacggatccg gagctggttc
     8401 tgatcgaagg gccgtccgat tttacagagc ttttggagga tttgacaaag aaggaggtaa
     8461 agcctccggt ggccgttatg gcctacacgt ccgatttgcc gatcaggacg attctctacc
     8521 ccctggccgt ctactcgccg gagtaccagg cggcgctgtg ggccagggat aaggggaaaa
     8581 aggccagatt ttttgatctg ccgtcctcgg tatttctggc gcttgaggat caggagaagc
     8641 tgtcggaaga aaatccggga gagaaagaca aggaaggccc ggaaagcggg gatactggaa
     8701 atacgggaga cgtctacgcc cgtcttgacc aggcggcggg aaccggggga aacgaggatt
     8761 tctgggagca cgtactggag cactccgaga cgccgaaagg ctatcagatg ggagcggctg
     8821 tctttggaac ggagcttcgc cgcctttctg agaacacaga gggagagacg gacagagaaa
     8881 acaggcttcg tgaacgctgc atgcttcggg agataaagaa agcggtggag gagggaattc
     8941 cagccagccg gattgcagct gtcacagggg cctttcacgt ggccgggctt ttagaggaaa
     9001 ctcctatgac ggacgaggag tttgccgccc tgaagcggct tcctgcccat aaaacgctga
     9061 tgccgtattc gtatttccgc ttgtcgggat taagcggata cggagccgga aacagagcgc
     9121 cggcgtacta cgagcttttg tgggagggca ggaagcgggg acaggcagat tacggggcca
     9181 ttcaatatct ggcccgtctg gcagctttcc agagaaagga aggaaatccc gtctcgtcgg
     9241 cagaggtgat tgaagccctg cggctggccg gcgccctggc ccgtctgaac ggatatgaaa
     9301 acccctcgct gcaggactta aaggacgggg cggcggcctg catggggcat gggaatatag
     9361 gggagctgtc tgtggccatg gcggatacgg agataggaac cacaatggga agccttcccc
     9421 agggcgtgag ccagacctct gtccaggccg actttaacag gaacctggcc cggcttaagc
     9481 tggagagatt ccgctcagtg acggctcagg cactggatct ggatctccgg gaaaagctga
     9541 ctgtaaaatc agagcaggcg gcgtttttag acttaaaccg atcctttttc cttcacagac
     9601 tgagaattct ccacatcagc tttgcctgcc tttcggacag ccgccagacg gaagctacct
     9661 ggaaggagcg gtggactctc agatggacgc cggaagcaga gatggagctg gtagagtcgg
     9721 tgttaaaggg agatacggtg gagcaggccg cttcgtttga gctgaaaagc agggcggacg
     9781 gggcggaaga gataggaaag ctgtcggaga ttatcaggga ggctttctta tgcggaatgc
     9841 cggaggccgt tgcctatacg gtgtcggcgc ttcaggccat ggcggtggac gcagtgtctg
     9901 ctccagagct ggcccaggcg gcgggagcgc tctctttcgt gattcagtac ggagacatca
     9961 gaaaacttga cagggaacct ttaattccgg tgcttaagca gctgttttta agactctgtc
    10021 tggtgcttcc gggggagtgc cggtgcgacg acgaggcggc ggaccgtttg attcctgcca
    10081 tggatacggc ggccagagcg gcggcagccc acgacttctt agacggacag cgtctggaac
    10141 ggacgtttcg ggagatttct gagagagacg acgtcaatac gaggctgtcc ggatttgcgg
    10201 gagccattct cctggaagca ggaaagatgt cagaaacgga gctgtcagca gaggtgtcca
    10261 ggcggctgtc caggggaatt cccgccgaat tgggagccgg gtggttcgag ggcctttcca
    10321 tgaaaaatca ttatggtctg attgccaggc tgtctctctg gaagagcctg agcggctatc
    10381 tggacacact ggacggggag gagttcaagc gggctctggt gttcttaagg agggctttcg
    10441 ctgattttac ctcagaggag aaaaataaaa ttgccgaaaa tctgggagaa atctggcagg
    10501 taaatccagc cgcagccagc gctgctctca atgaaacgct gacagcggag gagacgaagg
    10561 agctgctgga gggactggag gattttgatt ttgacgatat ttaaaaagaa atggccagac
    10621 tgatttggga gaggagggcg gccgatggac acgatggaac agatgagacg gtggaggctg
    10681 attctgggcg gagagagcga aacgcagttt gagacgatga acggatatgg ggaagccggt
    10741 ctttccaaag agcagcttct gatggatcag gcgttagccg ctatctataa cagcagcgcc
    10801 tacggaggat tcggatcccc gggaaacgct ggcaaaggag gcgggagagg accgtccaat
    10861 ccgcagatta ccagatggct gggagatgtg aggacgctgt ttgaccggga tttagtgaag
    10921 attatacagg cggacgccat ggagcggtgc ggcttaaagc agcttctctt tgaaccggag
    10981 gttcttgaaa atctggagcc ggatattggt ctggccagca caatcctgct tttaaaggat
    11041 cagattccca aggcgtcgaa agacagcgtg cgggagttta ttaaaaagat tgtggaacag
    11101 attaaccagc tgctggagca ggatatcaga agagcggtga cagctgcggt gaaccggaga
    11161 aaccattctc ctattccgtc tgcatctgcc ctggacgccg ccatgaccat acggcgggga
    11221 ctcaaacact acaatccaca gcttaaaaag atcgttccgg agcattttta cttctttgac
    11281 agaacctgca gaacggcagc agagcggtat acggtgattc tcgatgtgga tcagagcgga
    11341 tctatgggag agtctgtgat ttattcttcc attatgagct gtattctggc cagcatggcg
    11401 gcggtgaaga cgcgaattgt agcttttgac acgaatattg tggatttaac ggacaaatgc
    11461 agcgatccgg tggatctgct gttcggattt cagctgggag gcggcacgga tatagacaag
    11521 tcggtggcct attgccagca gtttatagaa aatccgaaaa aaactctgtt ttttctggtt
    11581 accgatctgg aggagggagg caaccgggcc tctcttctgc gccgcctgga ggagatcagg
    11641 cagtcagggg cctctgtcat ctgcctgctg gctatctccg acagaggaaa gccctgctat
    11701 gacgcccaga tggccggacg ggtggcggga cttggaatcc cctgctttgc ctgcgcgccg
    11761 gagaagctgc ccctgcttct ggaacgggcc tttaaaggcc aggatctgtc ggtgtttgag
    11821 aagcagaagg aataaaatga tggaaagaaa tagcgcggct ggcgaaggca gaacaagaaa
    11881 aattttccct tgttctgcct tttatattta agggaacagc agtttgtggt atacttggaa
    11941 gcagaacaga actaattttt tgcataacag gagaccattt tatgacttca tcacatacaa
    12001 ccggcgcgtc tgcccgccag gagcttacgc cgattctcaa gtgggtggga ggaaaacgcc
    12061 agcttttaga cttcatccgc cccctgattc cagagcacac cacctactgc gaaccttttg
    12121 taggaggggg agccgtattt tttgacctgc agcccaagaa ggcagtgatc aatgatttca
    12181 accaggagct gatcaatgtc taccagacgg tgaaggagca gccggaggag ctgattgagc
    12241 tgctgctccg ccacagggaa cagaacagcc aggagtattt ttaccaaatc cgtgctctgg
    12301 accgggagcc ggagaaatat gaggagctga ctccggcgca gcgggcggcc cggatcatct
    12361 acctgaacaa aacctgctat aacggcctgt tccgcgtcaa cagcgcgggc cagtttaacg
    12421 ccccctgggg ccgctataag aatcccaaca ttgtcccgga ggacaatatc agggccatga
    12481 gccggtatct gaacaagtct aagacgacaa tccgctgcgg cgactacagg gaagccctga
    12541 aggggctgag aaagggagcc tttgtctacc tggatccacc ttacatgcct ctcagctctt
    12601 cctcctcctt caccgggtat acggcgtctg ggtttggaca ggcagagcag atagagctga
    12661 agagacagtg cgatctgctg aacaaaaagg gcataaagtt tctgctctcc aattcctgct
    12721 gcgattttat tgaggatttg tacagcggat accagatcga gcgggttccg gccaagcggg
    12781 ccatcaacgc cagggcggac aggcggggag ccattgacga ggtgctggtg agaaactttt
    12841 aggagaggct gcatgggaat gatcgaggaa aaatggaacg ccctgtttga aacatacggc
    12901 attgcggagc aggtgaagag acaggggatt ttttcaatta cggcggatca gatccgggaa
    12961 tttaaggaac ccaggctgat gacgaaattt gacaccagag agtcggttcc cacggtgttt
    13021 gggaagcttg gcatcctccc tgtgacgagg ggaagctacg tgatcggaga tttttccctg
    13081 tatcacgatt ttccggagga ggagagcaga ggcggcgtaa tccaggtgga caggagcagg
    13141 attcccgact acctggagac tatcgacgtc cgcgacgtgc ggtcggaggc cgccgccatt
    13201 aagcttatca gccttactgg gattctggag gatttcctag gggaaaagcg gctggtggag
    13261 acggtatctg ggcgtatgtc ctccggcgct tttgactttc agattcactc cggggacaga
    13321 aagcatgtgt ccagaatcca ggtgaacaac tctcagctgg agattgacgg aggctttgaa
    13381 gggagagaca gctttgccat tctggagggg aaaaacgtag ttcacagcaa ttttctggtg
    13441 cgccagctct attatccttt ccgcctgtgg gagggccgcc tgacaaagcc agtgcggcct
    13501 gtctttctgg tctgttccaa ccagattttc agacttttgg agtacgaatt tgacgatccg
    13561 atggtgtacg attccatccg gctggtgaaa gaacagcggt acagcctgga ggacacgagg
    13621 attaccatgg aggatctggc cggaatcatg ggaagcgtgc ctgtaaagcc ggagccggag
    13681 ggcgttccct ttattcaggc cgacagcttt gagaaagtca tctctctcat tgagcatctg
    13741 ggagaaaagc cgctgaccat ggcggagatt gcagagattt tcggctttca ggagagacag
    13801 tcaggctact actataacgc ctgtgcctac ctggggctgg cagtcaggaa aaagggaaga
    13861 gacggagtcg tccgggctga gctgacagag cggggcgtca gcatcagccg gatggattat
    13921 aagaagcgcc agctggccta cgcgggcagg atactggagc acgaaatctt tcaccagctg
    13981 tttgaaactg cggtgcggac gggaaaactg ccggacaagc cgtatattca gaggaaaatg
    14041 aaagaattaa ggctctgcgg ggacagcctg atcggcagaa gagcttcctc tgtggccgga
    14101 tggctcagat ggatggtgcg tctgacagaa gagtaggagg agaaaacgat ggattcaaaa
    14161 gaagcaagag agagaatgag agcaggacgg ctgtactatg agagcggaag cgatctgggg
    14221 gaggagcagg ctaaatgtct ggagctttta tatgatttca atcagaccag gccgtcggag
    14281 gatgagaaaa ggcaggccct tttaaaggag atgtttgcag aatttgggga aaactgccat
    14341 attgagccgc ctcttcacgc caactgggcc ggtaaaaacg tccatttcgg agacggcgtt
    14401 tacgcgaatt tcaatctgac tctggtggac gacacagata tttttgtggg gaacagcgtc
    14461 atgttcgggc ctaacgcggt ggtatgtacg ggaaaccatc caatctgccc tgaaatcagg
    14521 agaaaacagg ctcagtataa ccttccggtt cacattgggg acaatgtgtg ggtcggcgcg
    14581 ggagccatta tccttccagg catatccatt ggagaaaatt ctgtgattgg agcgggaagc
    14641 gtggtgacga aggatattcc ggccaatgtg gtggcggtgg gaaatccctg ccgcgtgatc
    14701 cgtccaattg gagaggagga tcgaaaatac tacaatcacg gagtggagat agatattgag
    14761 tagtccaggt atttgataag atggattttg gaaaaacggg gtaagacaca ggggggggag
    14821 gcagaagcat atgaagaaac agaggagaag gcagatggtc agcgcggcgc ttgcaggtct
    14881 gtgcctggtt caggcgtcgg ttctttccgg ctgcagcgaa aaaacgaaga gcccacaggc
    14941 ggagactgat tctcaggtac atacggaatc cggggcagca gaacaagcgg gagataaaga
    15001 caggtatctt tactatttga aggacaatgc cctttaccgg gcagatatta agaatccaga
    15061 gaaagcggat ccggagctgc tggtggatca ggtgaacaag gatgagggag aaggcatttc
    15121 cagcagtctg gacatgaaat ggtcggagga tggaagctat gtgctggttc ccctgtacca
    15181 ggaggaggaa gagggccagt atatgcggct ctatgtgatt gaaaaccgta aaggcggtaa
    15241 ggctgaacgg atcgcagaga acgcgtcctg gtataagctg gagggaaata cgattgtttt
    15301 caatgaaaag agcagtaagc cggacatttc tccagaggct ttatactgct acaggccaga
    15361 ggagggagta tttgtcatct ctcagcaggg aggttccaat tatcctgttt taatgacaga
    15421 aagctgtgtg tgcttttctc ttcaaaggac agattttaag gagaatccgg tgagagaaga
    15481 cgtatactat tccgatttaa cctccaaaga ggcatccagc cctgtgctgc ttggggaaaa
    15541 cgttgcctat atagaaggaa tgagcggaga cggatctaaa atctggtaca caaaggaaga
    15601 taaagagaca gaccggctcc agctgtttct atgggaaaag gggaaagacg gcaaacagct
    15661 tttagacatg gatttggcaa acggctacgt cgcctctctg tctggggaga caggggaggt
    15721 gtactatatg gacaggaatc ctgaggacat ggcttctgaa agcggcagtc ttttcgacga
    15781 tatgaaggtt aaacaggaaa agcgggaaaa tggccagtca ggccccagag acgccctcta
    15841 ctattataaa gatggagaaa ccgtcatgct cagcgaagac gtatatgact gcgcttacgg
    15901 ggaggaggag ggaatcttct ggtatgagga agagagagca gatgaggaag gcgctgtggt
    15961 ccggtatctg gtgaaagacg gacagtcctg ggagctgaaa ggagtaccct gcgacggatg
    16021 cgagtacccg cagatgtaca gcccggagga agaatgctgc tacctggtat gctatgacgc
    16081 cgaggaggac gaagaagcgc tctatggctg gacctatgag tacaagctgg tgaaggcaga
    16141 tatgtcggac gggcatatgg gcgaaatgga gctgattgac acttcgctgg gagagattct
    16201 gttaagcagg gcagacgatt cccagatttt gtatgaaaaa aatataaata cagaaaatgc
    16261 agaagaattt ggaaatacag aattatatct caatggagag aaaattgcag aggatcctct
    16321 gacatacgga aaaatgaatg caggatcaga agatatttat gtgattgctc cctatgaaga
    16381 cagaaattat caatatttat catacaatta tgataattcc ggaacactga agcggatttc
    16441 agagggacag gaagagacgg tatcagagga ggtcaccaat gtatcggcgg cagacgattt
    16501 cctggtgatg ctgactgatt acaggaatcc agagttttac ggaaatctga agctttatca
    16561 ggatggccag acctgcctga tagacgatca cgtggagagc ttttacatca gagatatcga
    16621 cagatccttg tccgcgccca gctattatct gcagcgggac gaagagacag aggagagtgg
    16681 agatatgtcc ggcatgttcc cggatttatt cggccagaca gaagcccagg atgatgagga
    16741 ggcagcgacc atagaatttc cagtggaaga cgaggcgtat acgggtgggc tgtccgcgga
    16801 agaaacggca gagcagcagg actgaccgtc tcaatcagaa agaaatgcag ctgtgcgggg
    16861 aaagaattcc ccgcacattc tgcctctgct attccggata gatcagatgg ctgtcgtcaa
    16921 ttacgtctaa aacctcccgc aggaagcgat cggccagcca gttggccata ggcaggttca
    16981 tatccagata atttccgcag tccctggcgc aggctcccgg aacctcgccc tggtaatccc
    17041 tgataaaggc gaacatctcc ttcatcagag gcacaatgtc tctggcttca tagtctcccg
    17101 acaggagcag atagaagccg gtgcggcagc ccatggggcc gaagtagagc acccgctctt
    17161 tccagagact gtggtttctt aaaaaggtgg cagccaggtg ctcgatggtg tgaacctcag
    17221 ccgtgttcat gaccggctcg aagttagggc gcgtcatgcg gatgtcaaag gtggtaataa
    17281 ccgcgttgtc cgccttgtcc tttctggata cgtagacgcc cggcagcagc tctaaatgat
    17341 tgatggtgaa gctagtaatt ttatccataa gaattctccc agtatagaaa tttgcagcag
    17401 tctgctgtaa atatcagtgt agcagagatg ggaagggaag acaagaaaat ttgaaggccg
    17461 ctggaatatt tcccctgccg tttatgggag aaaagatgaa aacagatgaa cttgaaactg
    17521 aggcgattct gtactataat gaactcatat tgattagact ctgcacagcg gagaaacata
    17581 aggagatcac gatatgttag acggaaagaa aacacttttc agcggtatgc aggcaacagg
    17641 aaacctgact cttggaaatt atctgggagc gctgaagaac tgggttacta taagcgacga
    17701 gtatcagacc tttttcagcg tggtggatat gcactccatc acagtgcgcc aggatccggc
    17761 cgagctgaga agaagagcca gaaatctttt gactctctat attgccgcag gtctggatcc
    17821 ggagaagaac tgcatttact accagtccca cgtcagcggc catgcggagc tgtcatggat
    17881 tttaaactgc tttacctata tgggagagtt aaaccgcatg actcagttta aggataaggc
    17941 ggcgaagcac gcggacaata tcaatgccgg cctttttacc tacccggtgc tgatggcggc
    18001 agatattctt ctgtaccagg cagacgtagt tccggtaggc attgaccaga tgcagcatct
    18061 ggagctgaca agagacattg cgatccgttt caacaacatt tacggcgacg tgttcaccgt
    18121 tccggaggcc tacatcggaa aggcgggagc caagatcatg agtcttcagg attcggccaa
    18181 gaagatgtcc aagtcagacg agaatccaaa cggcagcatt tacctgatgg acgatccgga
    18241 taccattatc cgcaagttca agagagctgt gacagattct gaggcctgcg tccgctactg
    18301 tgacgagcag ccgggaatta agaacctgat cgacatctac agagcctgta caggaaagac
    18361 tccgcaggag gttgagaagg agtttgacgg caagggctac ggcgacttta agatggctgt
    18421 cggcgaggcg gttgtggacg tgctccgtcc tcttcaggag agatatgcag agctttccaa
    18481 ggacaaggcc tacattgaca gcgtgattaa gaataatgct gagaaggctc agtatttttc
    18541 aaataagacg ctgcgcaagg ttcagaaaaa ggtgggcttc ccggagaaga tccgctagag
    18601 aaagccgctg gcgcggacac ggccagggaa tatttttaac aggtgtaaga gaggaatcca
    18661 tgaatgcatg ggttcctttt ttcatctttt tacatattca tccagttgac tattgaacat
    18721 ctgcctgaat ttttttataa tatatctgat cagctgggag aagacaggta ttttgccggc
    18781 ttttggcgtg ggggcagaga acagggcgcg ttttgctgca gaaagcagcg tttctgttct
    18841 gggcggacgg aaataagatt ggaggaaacg gctatgaaaa aaattatcaa cagtgtggag
    18901 caggtggaga atgagatggt cctcggcatg gccaaggcgt atccacagta tgtgagaaag
    18961 ctggactgcg gaaacgtggt tgtccgcgcc aacagaaaag agggaaaggt agcgctgatc
    19021 agcggcggag gcagcggcca tgagccggct cacggcggct atgtgggaga gggaatgctg
    19081 gacgcggccg tatccggagc tgtatttaca tccccgacgc cggatcagat ttatgaggga
    19141 atcaaggcag ttgccacaga ccagggcgtt ctcatggtta tcaagaacta tacgggagac
    19201 gtgatgaact ttgagatggc cggagagatg gcccagatgg agggcatcaa ggtcgctcag
    19261 gtcgttgtaa acgacgatgt ggccgtaaag gacagccttt acaccgtagg ccgcagaggt
    19321 gtggcgggaa ctgtgtttgt acataagatt gcaggagcca aggcagagac aggcgcttcc
    19381 ttagaggagg ttcaggctgt ggcccagaaa gtcattgaca atgtaagaac catgggaatg
    19441 gccatccgtc catgcaccgt tccggcggca ggacagccgg gctttgagct gaacgacgac
    19501 gaaatggaag tgggaatcgg catccacggc gagcctggaa cccacagaga gccccttaaa
    19561 aaggcagacg agatcgtgga tcttctgtta gagaagattt tagccgatct ggactacagc
    19621 ggaaaagagg tggcggtgat gattaacgga tccggagcga cgcctctgat ggagctgttt
    19681 attgtaaata accgcgtatc agacgttctg gctgagaaag gcgtcaaggt ttataagacg
    19741 ttggtgggcg agtacatgac gtccattgag atggagggat tttctatttc actgctgcgc
    19801 ctggacgacg agctgaagga gcttctggac gcaaaggcag atacgccggc atttaaggct
    19861 taagaagcag acggcggggg aggccttttg cgcttctcct gccgtttcag attacaggat
    19921 ccgccggata gagggcggct gtcctgaaaa atatgagaac aggagatggg ataatgacag
    19981 acagcgctaa gataattgaa ctgcttgaca agatcggaga taagattata gaggaaaagg
    20041 agtttctgac agagcttgat aagccgatcg gagactgtga ccacggcatt aacatggcca
    20101 gaggcttcgg cgaggtgaag aaaaagctgc cgggtatggc ggacagcgac ctgggaacta
    20161 tctttaagac taccggcatg accctggtat ccacagtggg aggatccgcc ggaccgctct
    20221 acggaacggc ttttatgaaa atgggtatgg ctctggctgg aaagaaggaa atgagcttta
    20281 acgaattcct gacagccttt gaagcggctg tggagggcgt aaagcagaga ggaaagtctg
    20341 acaggagcga gaagaccatg ttggatgcca tgatcccggc gctggaggcc atgaaggccg
    20401 ccgcagcaga gggcaaagac gcagaaacag cctggaagga aggcacagag gcggctgagg
    20461 caggcgtaga gtacacgaag acgattatcg ccaccaaggg aagagccagc tatgtaggag
    20521 agagaagcat cggccatcag gatccgggag cgacttcctt tacctttatg atggagacag
    20581 tgggagcggc gctttaggag aggaagtaaa acggaggaga acagatggta ggaatcgtga
    20641 ttgtgtccca cagtaagaac ctggcggaca gtgtggtgga atttacagga ttgatggctc
    20701 ctgacgcgaa gattgcggcg gcagggggta tggaggacgg cggcttcgga accagcttcg
    20761 agaagattca gaaggccatt gaaagcgtct actcggagga gggagtcatt gtcctcatgg
    20821 atatgggaag cgcggtgatg acgacggaga tggtgcttga catgtttgag ccggataccg
    20881 ttaagatggc ggactgcccg ctggtggagg gagcggtggt cgccactatc aacgcagtca
    20941 gcggcatgaa gatggatgag attctggcgg ctttaagcca ggtggcaggc acgccgaaat
    21001 tctagattta ggacataaga aggagggtgg tatatgagaa gatggagaaa ggcggcagcg
    21061 gtccttatgg ctggcgcgtt agcggtggca gcagtgtcgg gatgcgctaa gaagcaggat
    21121 cccaaagaaa tttacagcgc ggcgatggag aagaacagcg ccctggacag cgttgacatg
    21181 gacgtgacga tgaagatggc catgacggcg gatgaggaga gcatggatat ggaggtctcc
    21241 agcaacacca agatggatca gtcggataag gagcacgtaa aattcatcac agcttcttct
    21301 gtggctatgg acggcatgaa tatggagaca accgtatttt atgaggacgg ctactattac
    21361 atggaagcca tgggccagaa aatgaaatat cccatggatc tggaaagcct gactgcccag
    21421 atacaggaga gtgtgggaag cactacgctt ccggtggaaa gcctggatac tgttgaggta
    21481 aagaaggacg gggataacca gattctcacc tttactgcca atccagagaa gatgaacgat
    21541 tatctgggcc aggtgatggg cgcgatggga gacgtaagcc aggtgtccgg cctgaatatg
    21601 accatcaatt ctgcagacgg cgagtatacg attggaaaag acggctatta tacagatatg
    21661 aagatgaatc tggatctgtc catggagtct cagggcgcgt ctgtgggtat gattctcgac
    21721 ataacgggaa ccgtccacca gccaggacag ccggtggaga ttacccttcc cgacacagcg
    21781 gactatgtgg aaattgatcc agccctgtta ggagccagct agactgggcg gaaggttaag
    21841 aacatgaaat gaaggagagc ggcacgtttc aggccgctct cctttgtcaa tatggaatgg
    21901 ttatgtaatt gttatggaat ctgttatgga atcctttagg aaacggcagt tattcctctg
    21961 tctccttata attgcttaaa tcataaggtg tggagagaat tgcaatggca atcaccgtga
    22021 tcagcagccc tgcaatcatg agaacgccgg aaccgttatg caggaattta atcactgctc
    22081 caatgggaat cagcccgttt ccgaaaaaaa ggaggatcag gaaatatacg cgtcccagaa
    22141 tgtttccatg tttcgaatct aaaaatttct gaatattcat tatgaaggcc acactcccat
    22201 cttactcata ataaaggtga taaacacaat gttcagcaca gaaatgcagg ccagaatgcc
    22261 ggcattgaaa aatctggact gaatcacttt ctttccaagg tatctgggat cattgcccag
    22321 aagataccag gagtttccgg agatccagtt gaacagagac tgcatggctg cgataaagac
    22381 tactaccata accggctttc cgaagaacgc gcctaagaag ccgatctggg gagccagcac
    22441 gataaatggg tgataccagg cattggtatc cttcttcacg tttgtggact gatagaagga
    22501 cgtagcgcag gtaacgctca gtccgatcat ggaagagcat accagagcga tgatgccgat
    22561 gtagaagcca atctgaatcc agatggatgg aatgacagat acaagagcgc tgcagagctc
    22621 tgtggagtcg gttggaattc cttcttttcc ggcaaaggcc tcggcgaagg caatggagac
    22681 gaaggacagt accagggtaa ccggcactaa acctccgaat acagcgtcga atcgtcccag
    22741 agtctcgtga ttttcagagt agccgcggga ttccatgccg ttgttgaaca gcacccagtc
    22801 cataacgccg atggtggcgg tcagggaggc gatcagcata acaataccgt cgattccgct
    22861 tggcagagtc gggattaaga gtcccttgat catggccggc atgtcgatgc ctgtgacgca
    22921 gagcacggcg ccgaatacca ccagcatgat tccgattaag attttcatgg cattctctac
    22981 gatgcgcacg ccctttgggt tatttccgga tccatacatc agagataagg gaacggagac
    23041 agctaccaga agaatccagc tgatgttttt gggaacgttg atatttacaa tggagaacag
    23101 ggcggtcacg gcgtccgcgc ccagggcgta ctgtccaaag ttgtatacga tggaggcgat
    23161 gaagcaggcg attaagcctg tggccagact tccgaaaaac ttgccgtgga acttgtcctg
    23221 agccttgata acagatattt cagaggcagt gacaaaacgt gtggacagag ccagcataaa
    23281 aagtcctaaa gcaaaagaat agagggggat ccagagcatg tcgtagccgt aggcggcgcc
    23341 cagggtaacg gagcttgcaa aggatcctgc gcccagcgtg aaggcggcgt tcataaagcc
    23401 tggacctgag agcttgcagt agccgaaaaa tttctgcaag ggcggttttt tgttcagttc
    23461 actcagaaac gccttttccc gcagggcgtt ttctgaataa cggggattgg tttccgtttg
    23521 attcatgtga tgatatcctc ctgtagataa taagtacgat ttacttgtcc aggcgcgtca
    23581 cgatcatttc acagggcgcg caggggccgt cagtgaacag agacgggcgc tcaaatttga
    23641 ttttgccgaa aaacgcttcg ttcagagcca gatcaatttc ttcacagtaa agctttccag
    23701 cctgttccag accgatttcc cggaatgcgg tggaaaacgg acagacgcgg ttgatttccc
    23761 tgagctgatt gccctccacc gaggactcgc agtcccaggc ctgattatca ggataatcag
    23821 agtattcctc cactgtgtgg aacgtcactt cctttccgtc cttccggatc cgctccttaa
    23881 tggcgtctgc ccttaaattg gcaaagcgcc ggactgccct cctgacggca gcctccccct
    23941 tttcatttcc catttcccgg atgatctcgt ccgccatgac ggcaaacagc ttcgccatgg
    24001 tttccgtgac ctttccaacg ggatcatttg gattgtacat atgcttcccc ctttcaatcc
    24061 atcgctgtca ttcgatctat cagtattata ataaattacc gcagtaaaga atgggaaatg
    24121 ttgtaaacac cgggaaaaat gtagtgaaaa gagcggaaaa agaatgcccg gggaaaaatt
    24181 tccctgggca taggcggaga ctggagaagg cttttctttt tcttctacac gccgaacagc
    24241 acaaaggaca cttcaaaccg gccctgttct gccctgatgt tcaggtttcc gccgtatttt
    24301 gccgcagctt ccctgacatt ggatagtccc aggccatgct gttccgggct tggtttcgta
    24361 gtggggaaac cggcgcggac aggaacgtcc tggctcatgg aattggagaa tccgcagacc
    24421 agcatatttt tcttgtacag aagcttgaca gaaattctgc gctgctctgg ggatctgatc
    24481 aggcggcagg cctcgatggc gttatccaga atgtttccaa agataatact gcagtctgcc
    24541 atgtcgatat tcatattttt tatcaccatg atttctgtgt ccgtctgaat gtctgcttcc
    24601 gaggcctgct ccagcttgga tgtgaggacg gcgtccagaa aggaatttcc tgtatttatg
    24661 atacagcggc gggccggagg cgacagctgt tcctgaatgc gcgcaacata gtcgagaacc
    24721 tccctggatt ttccttcaga gagaagcgtc tgaaccgtct gccagtgatg cttcatgtcg
    24781 tggtgcagac ggcggaattg ttcgtccctg gtttccatct gcctgtagtg gcgtacctgc
    24841 tcgtttaact gctgttccag gcttttccgt tccaggctct gtctgtaaat ccgggccgtt
    24901 tcaggaacga agattgaaaa attgtagaga atcaggcata cagagccgat cacaaggctt
    24961 cgtatggcca ccataggctg aaaattgtaa aacagcagat agataaaaaa ggtaaaaaag
    25021 ataatcagga tgccaatgta cacagtatgc aaaggtttgt tttccgatac ctcagcgctt
    25081 aaaaagcaga tgcagacaat cagcgtacag ataaagagaa accacagaga ctgctccaga
    25141 cggtagaacg gaagggaacc agccatcatg gccaggacgg cagagagcag aaccacaaag
    25201 tgaaacaggt ataaaaaagt gaagatgccg ggatacactc tgggaaattt caggcggatg
    25261 taccggtaca gaagcactgg aataataaaa atggacacac atttgatcat atcaatggag
    25321 aagccgtcca aaacagacag ggccagagaa gactcacaca gaatccagat tccatagcca
    25381 aagaagcaga aaccgatgga gaaaatgtaa gtttgtattt tgtatacata ttgaaaaaca
    25441 aatccggcgg ccagaatgac aaacgcgacg aaaaacagaa ctgccgccgc cacgatgtga
    25501 aggctgccgg acatggccag attactcagg agagcatttc gggatccgaa gcagattctt
    25561 ggcgtttccg acaggatgta ttcgccgcag gattcgcgaa acagcagact gggagccgtt
    25621 tgcaaaggtt caaactgaag cctgaggcgg gaaaaggaag attcttcctt ctggctcagg
    25681 ggaatgagaa accaggtttc agaatcaagc gcaaaggttt cgcagctgtc aggcacaggg
    25741 attttccttc cgtccgccca tatttctgac ggcagctggc cgctgacagc cagggtgggc
    25801 tgggctgcct ggacagatgg gagcgggcag cagaaagaaa gggtgtcttc ttctgcctca
    25861 gagctttcaa aatgaacggc tccgttagat tttgtcagat ccagaaagac gtggtaagag
    25921 tcggtgggac gttcgttctg cagggagagg agaaacactc cggacacagc cagaaagaac
    25981 acccagaata tgcggtaaat gcggtttgcc atggaaattc ctcctctaaa tcatagaaag
    26041 gccgttcaga aggtaattct ggtactgctc cactgcaccg gcatacttct gtccaatggg
    26101 aatgactgtc tgatcaacgc agacaaactc ccgtccctgc agatagtcta cattctcaaa
    26161 attgacgatg taggaacggt ggacccgttc aaaggaagcg gaaagaagct gctgttccag
    26221 atccttaatg ttgccgtaaa actcaatcgc aggcccattt ttcagatgaa tttcaataat
    26281 tctgtttttc acttcaaaat acacaatatc ccgaagcaga acagacccaa tggttttgcc
    26341 gaatttatag gtaaaggact ggcgctggct tttttcagcc agggaaacgg cccgcagaag
    26401 caccgtttcg atttttcccg tgcccacgtc ctgctttaaa aggtagtgga gcggcatcac
    26461 gtccagggct tcgaagacgt gttccttgct gacggtgaga aaaataatct gggctgtagg
    26521 gctgacggcc cggagtctgg cggctgtctc cacgccattg agctgtttca tcagaatgtc
    26581 gagaaaatag atatcaatgg gctgtttcat ttcttctaag tgaaataaaa gctcttcacc
    26641 ggagctgaaa cggcagacag aagcgcagat accgtgtttt ttgcagacgt cctgaatcag
    26701 cccgctcaga cggcttccca tagcgtcgtc atcatcgcag acgcagatat gtatcataaa
    26761 ataatccccc ttcaatccag acgccaggca tttagaacaa gacggtttcc tgcactccgg
    26821 cgttccaatc aaattatata ggaaagcagg gggaaaagca acgaagaggc ggttcacaaa
    26881 cagcttttta tatgttagaa tagactgcat tcattacatt gtcagatcgg aatagattcg
    26941 cggagaggga agctgtcaga tctggccaga ttcacaggca ggaaagaaga ggacagagat
    27001 atgaagatag cagttgctta tgacaacgga aacgtatttc agcattttgg aaaaacagaa
    27061 tatttcaagg tttatgaaac agagaataac caggtggttt caagcgaggt gatcagctcc
    27121 aacggagagg gacacggcgc tttagcaggc gttctggcag cgcagtccgt gaacgtgctg
    27181 atctgcggag gcctgggcgg aggagcacag acggctctcg acgaggctgg aatccaggtg
    27241 ttttccggcg cgcagggaag ctgcgatgaa gctgtggagg cttatctgaa gggagagctg
    27301 gtttccacag gcgtaaactg tgatcaccat gaccacgagg agcatgaaga gggccattcc
    27361 tgcggaggct gcggaggcgg atgcagcggc tgcggaggcg gatgcggttc tcagccgcag
    27421 attatcatgg aggggcgcaa tgcaggaaag ctgtgccgtg ctcactacag aggaacgctc
    27481 aacgacggaa cacagtttga ctcctcctat gacagaggcc agccattaga gtttatctgc
    27541 ggagtaggcc agatgatcaa gggctttgac gcggcagttg tgaatatgga gccgggccag
    27601 tcagtggacg ttcatctgat gccggaggag gcttacggca tgccggatcc ggatgctatt
    27661 tttacagtgg agattgcgca gcttccagga gcagagaatc tggaagtcgg ccagcaggtt
    27721 tacctgtcca atcagttcgg ccagcccttc ccggttaagg taacggcaaa ggacgagaca
    27781 aacattacct ttgacgcgaa ccacgacatg gcaggcaagg agttaaactt ccatattgag
    27841 cttctggaga cagaataagc agaaagcgga ctgctgaaat ttcatattgc agataatcag
    27901 aaaaagagat tttccgacgc cttccctatg gggaggcggg aaggtctctt tttttgattt
    27961 ttatggcgga aagaggtccg gcctgcacgt ctcagactgt ataaagaata tcaataagca
    28021 gactttttta tggataaaat caatttctta tttgttccag attgtggtag cctaatagtt
    28081 agaaaattta ggaaacaagg aacaggagag gaaacaatgt cggaacatgt gcaggctgtt
    28141 atggaacaca attcggaatt ggaacagctg gggaatctta cccgccgtga attaaaggaa
    28201 ctggaagaga aagagaaaac tccggttcag aaagtggaag aagcgctgat catggctctt
    28261 cctgccgtat gcggggccgc ggctttatcg gagtaccttt tgattccgga tttagcaaga
    28321 aataagaatc ccatgtacta tgtgtacgtg ctggctgcca tgatggcagc ctacttatgc
    28381 gcgggtctct ttgctgcctt taaaagacgg aggggaaata aggtttacta tgagaaactg
    28441 cgctatgggg cgccccgcat ttcggctctt tttctgcttc tggcgctgta tgattatctg
    28501 actcttaaga caggtacgct gacgcagccc tttgtcccgt gcatgaactt tattatcaac
    28561 gcgtttgtat cggattaccc catgttaatc gagtgtacca tgcacacgct gcggcttctg
    28621 atgatcggct atgtgatcgg cgtcagcctg gggctggtaa cgggaattac ctgcggctat
    28681 tccaggcggg tgcgctactg ggttgacccg gtcatcaaat ttctggggcc gattccgacc
    28741 tctacctgga ttcctgtgat tatggtaatc gcctcctccc tgtttgcggg agcggtgttt
    28801 atcattgccc tgggttcctg gtttgccgtc acagtggcct ctctgaccgg aatctccaat
    28861 gtggacaagg actttttcga ggcggccaga actctgggcg ccagcaaaag gcagctggtg
    28921 ttccgggtgg cgattcccca cgccatgccg tcgattctgc agggctgtac ccaggccatg
    28981 agctcttcct gcgtggctct tatgatcgcg gagatgctgg gcgtaaaggc cggacttggc
    29041 tggtatatga catggcagac gggctgggcc agctatgata aagtatttgc ggcgctgttt
    29101 gtgatctgcc tgatcttcac tcttgttacc aaggcgcttg aggcggtgaa gcatcatgtg
    29161 ctccgctggc agaatggagt tgaaagtaat ggaagataaa aaggtaacat taaagcttga
    29221 aaatgtgagc aaggtgttcg cgaaggtaga gagcgacgac gtgacgcacg ccttatataa
    29281 cgtaaacgtc cagatggaga gcggggagtt tatttctctg gtaggcccgt ccggctgcgg
    29341 aaaatccacc attctccgcc tggtggcagg ccttattacc ccgactctgg ggacggtttc
    29401 tgtcaatggc gcagtggttg agggaccgga tccgaaccgt gggatggtat tccagaagcc
    29461 cacgctgttt ccatggctga cggttgagaa gaacattgcc ttcagcctgg aaatgcaggg
    29521 aaagctgaag ggaaatgaag agaaggttca gaggatgtta aatatcatcg gtctggagca
    29581 gtttaaggac gattatccgg gacagctctc aggcggcatg gcccagagag tggctctggt
    29641 ccgttccctg atcaacgagc cggatattct gctgttagac gagcctctgg gcgctctgga
    29701 cgccttcacc cgcatgaaca tgcaggatga aattttaaat atgtgggccg ataccaggca
    29761 gctggccctg atggtcaccc acgatgtgga cgaggctatc tatatgggaa ccagagtgct
    29821 ggtgatggac gccaatccag gccgcattgt ggcagaaatt aagattgacg gggcttttcc
    29881 gagagatcgt tcctccgcgc agttcgtgga gtacagaaac gagattttga atcagctgca
    29941 ctacggcgga aaaagaggtt aactgctttg ctttgaaatc gcctcagacg attttaagaa
    30001 taaaaaacga aggagatagg gaactatgaa aaagaaacag attgcagcat cattactggc
    30061 ccttacagtg gcatgcagca tgacggcgtg ctccggtaag ccggaggagg cggctgatac
    30121 gacggcggct gccgcagagc agggagaaat tgccggcgac acaaacaacg acggccagat
    30181 tgatatggga gtggacgaga atgtagaggt aaaacaggag aacgcgtcag agcatatgga
    30241 ctccttcgag gcttccacat ccggaaaatg ggaggccatg ttcactcctg tcgatatgga
    30301 aggacgcgcc attgacatgg cagattttga cctgactcca acggaggagg agttagaggc
    30361 gatgaagaaa gagccggctt acggacagaa ggtgctctac tacatggcgg acggatgtac
    30421 ggcaggcccg acggtggcag cccaccttgg atactacgag gaggctggac ttgaggcaga
    30481 gggcgtaaag ggaaattctt atacagaggc ccttggaagc ggccaggcga ccgttgcggt
    30541 aggacacatc gcaaccatgc tggttccgat taccaataat gtagatatta cctttgtagg
    30601 cggcgcccac attggctgca agtccttata cgtgctggct gacagcgagt acaatacaac
    30661 ggaggatctg aagggaacga acatttccgc tccaaacgga atcggaaaat ccgactacaa
    30721 cattacatgc ctgctgttag acgcagacgg aatcaatccc caggaggatg taaacatcac
    30781 cgcagtttct gccgacgcct gcctgacggc catgacaaat ggagaaattt ctgcagccct
    30841 gctttccgat accttcgcct acggtctggt aaaggacggc actctgaaat gcgtgcgttc
    30901 cctgttagac gaggacttcg cagatgagaa ctgctgcatg atcgccatga accgcacctt
    30961 cgtaaaggag aacccggtta tctccaagaa gattacgcag gccgttcaga aggcccattc
    31021 ctacatgcgc gacaacccgg aggaggcgac tcagatgctt ctcgatcagg gctggaacgg
    31081 cggaagctac gagatgaacg taatgctcaa taattctctt cagttcggcc tggaccagga
    31141 tttcacagag gtttctttaa gagacgtcgt tgagaagtac gtgagactgg gactgatcca
    31201 gaacatggac gatacggatg agattatgtc cattgcgtgg acgccggttt tagactagga
    31261 tccatgcaga taaaaggggg ttctggcgga tggggggtct tctgtccgaa cagaggtatg
    31321 aaaaagatca gagatacagc cgcatgagtg acgcggcaga atgtcaggag aattcccatc
    31381 gaggcttgcg gtgggaattt ttcctgtaca tggggaaatc gggtacgaaa gtgaagaaaa
    31441 ggagagaatg atggtgggaa gcaacgaaac gaatcgaaga aagcaggaga aaaacagtct
    31501 tatttttgcg gcggcgcagg ctgtccacgc cctgctttta attctggcgg taaaggtatt
    31561 tgcgcctgtc tgtacaggca tggtggacac ggcagcggga aagcaggttc ccatgcggtg
    31621 ccactatacg gcggttctgc tgctgttttt aggccttatt ttactggtaa acgctggttt
    31681 atgcgcagtg cgaagggaga tggctgtgtg cggaacgata acggcggttc tctccgctct
    31741 ggcatttgcg gcgctcagtt cctcgatggg aaccggcatc tgcctgaatc ctgagatggc
    31801 ctgccatgtg acggcgtcct ttgtaaaggc tctgggagga attggaatcc tgattggcgt
    31861 cctctgtact tacatgggag taaaggccgg aaaataaaca gaaagaggaa agattctaaa
    31921 tgaaacgcga taaaaagtta agcgctctga atatggcggt tcagaacctg aaggcgaaga
    31981 aatcccgcac gctttttatg atgtttttcg tggtgctgat ggcagcgact gtgtttttca
    32041 gcaccattct gatggacaac atgaggcggg ggattaagag caccacagag agggcgggag
    32101 cagatattat tgtagtgccg gacgagggca cggaagatat cagagattct ctgtttgccg
    32161 gaaaaccatg ctccgtattt ttcgaccgct ccatgaaaga agcggtggag caggtagagg
    32221 gcgtggaacg ggtttccggg cagatgtatg tggggactct ttccgcctcc tgctgttccc
    32281 ttcctgtgca gatgattgcc ttcgacccgg aaactgattt tgtggtgcag ccgtggctga
    32341 aaaaccagaa tgcggtccgc ctggaaaagg ggcaggttct ggtaggcagt tcagtggtgg
    32401 cggaaccggg agagacgctg cagttttatt ctacagactt tcaggtggca ggaaagctgg
    32461 aacggacggg aatgggatat gacagctctg ttttcatgac gtttgaaagc ctctatgagt
    32521 taaaaaattc tgagacagcc atgaataacc tgcctatgga ggacattgaa aataagcttt
    32581 ccatgctgat ggtagatatc agggacgata ttaaagatct ggatctgatc cacctgcgcc
    32641 tggacattgc caaatgcggg ccggagggag aaaagatgta tgcaggcagt acggacgagc
    32701 tgttaagcgg cgtatcaagc caggtgaaaa aactgtccgg atacggaaat attctgacct
    32761 atatttccat tctctccgcc gccctggcgc tgatcagcat ctttgtcatt acaatcaatg
    32821 agagaaaata tgagttcgga gtgctgtacg ccctgggagc gaaaaaaagc catatgagaa
    32881 acattattct ggctgaggcc ctgatgatca gcggagccgg aggaattctg ggcgtgctgg
    32941 cggcctacgg cctgacggcg gcttttgccg acgtaatccg ggtgcagctg gacattccat
    33001 atctgaatat gagcctggct gaggccgcgc ctgtggcagg actctgcatc ggccttgcgc
    33061 ttttgacagg aatcgcggcg gccgtatgct ccgcatatca aatcagcaag ggcgaagtat
    33121 accgcctgct tagggagaat gagtaaatga ttcaggttga acatgtgaca aaacaattta
    33181 cgagaaatga cagggatttc gacgcagtcc acgacgtgtc cctggaggtg aaaaagggag
    33241 agttcgcggc cattacaggc cactccggaa gcggaaagac cacgctgttc aatatgatgg
    33301 cagggctgac tgcgcctctg tccggaaaga tttatatcgg cggatccgag attacaggga
    33361 tgaaggaaaa tgagaaggca gtcttccgca gccagaatat gggatatgtg ctgcagggac
    33421 agagcctttt gaacaatttc acgattctcg acaatatctg tatgcccgcc tacctgtcct
    33481 cccaggtgaa ggaatttaag gagagggccc tggagctgct gaggcagatc ggcctggagg
    33541 aatttgcagg agagtacccg gccaacctgt ccggcggcga aatccgccgc gttgccattg
    33601 tccgggccat gttaaaccag cccaaggtca tcctggcgga tgagcccacc agcaacctgg
    33661 acccggaaaa ttcccacaag gtgatgcaga tgttaaagga tatcagccgc tccggaacca
    33721 ccgtagtcct cagcacccac gagctggagt atttaagcta cgtggaccgg gtatttaata
    33781 tgaaccgggg aaagatggag gagtagggga gaagaggata acaggagatg aaacatgaaa
    33841 gcagacccgc caaggcgcgc agagtgccga ggcgggtttt gctgttggga aagatgattg
    33901 agattgctgt tgggagatga taaaatacag ataaggatgt tggaatgatg gagataggag
    33961 atggggaaag acagaagagg agaggaaaga tggctgaatc tgattttcag aaagcagagt
    34021 cccagctgca gatagatgcg gagtattaca atacactgga tattggggga ttttcaagaa
    34081 tgctgaagga tccgtcctac tgttataaat tttattggct ggaagcgatc gtgaagctga
    34141 tttcagagga cagacaggag gtttcctatg atgaaatgat caatgagatg atttccaatg
    34201 cctggtattc tgtgctggaa ttccatgtgc atctcagcgg tatttgggga gacggagaaa
    34261 tcaaagacag cctggaaaag gcagtattga aattatatag actaagcggg ctgccagcta
    34321 acgcatcaaa agtggaaatc aaaaataaaa ttgcagaatt tgacaaagag ctgcatgaag
    34381 agaagatggt gctgacgaaa aatgtgccct ataaagccct gtcgggattt gccaatcgaa
    34441 gttcagagta cattgattta aacagcagcg ccggcagaat gatagcttac tacaatagac
    34501 tcaacagcag aggaaccttg cttctgtata cctttgacag tcaaaaaggc ctggaacgga
    34561 aaatcatctt tcaggaagca tggattcaga tgattcagga tcagatgact gccattttag
    34621 gatggattca gtatgaaaag gtacgctggc tgcagaacaa taacccagaa gttccaggcc
    34681 ttgtatacaa actgatgccg ttagacgata aaatgaggaa acttgcccat gtccgaagac
    34741 tgtgggaggg aatcctggat acaaccagta ttacagatgt gtttaagcat gaaccaatta
    34801 aaaaggaatc ctacgatgta gaccatttca ttccatggtc atttgtgatg aacgatgaac
    34861 tgtggaattt aatgccaatg gattcctctc tgaattcctc aaaaagcaac cgcctgccgc
    34921 agtgggacag attctttgcg cgttttgctg aaaatcaata cattatgtat gaactgattc
    34981 acggaaaagc aaggataaga aagctatatg aagcctgtta ccgcgataat cttcattcta
    35041 tctgggccag ccaggaatta taccggaaag ggaatacgag aaaagagttt ttcagcatat
    35101 tagagaaaaa tatgcgcccg gtttatgatt ctgccagaag acaggggtat gaggtctgga
    35161 gggtgtaggg ggaataatac taaagctgca atgacagatg gggcattcta cggtgacaga
    35221 ttgaaaaccg atatatgaat ttgctgcatt gaaggcagaa gcggaaaagt tacagataaa
    35281 tgcagacatt tccgaagagc gtgcatttgt ataaaaatag ggagtagata tcatttgacc
    35341 caaattctca aagcacataa aatgggaaaa atagaagtgt cccccaaggg gaatggttaa
    35401 atggttctac ggggagatta ctacagaagg gaatgatgtg aatatttaag agaaaacgtc
    35461 ctgcagatgt gggacgtttt tgatgagatt tcaaagatag agctgacttg aaattctaaa
    35521 aataagattt tgctgataaa aaacgggaga aaatatggta taataacgag gaaattagct
    35581 gtcgtacttg catgaacagc tatctgacga gaaaaccatc gagacgatag ttgagatggt
    35641 gtacttataa cgatagattt gtgactggaa aagtgatcgc atgaaaaatg tggggtaagc
    35701 tatgcttgaa aataaattgg gtattacaga ttctacagaa ttagcaaggg cagaagaaaa
    35761 aatcagtaag caaaaagccg ttgaaatgtt tgaaaacggc ttttttgaga cgttagaatc
    35821 agggacttat aaaagtcttg cgatgattca tcaatatctt tttgatgaga tttatgattt
    35881 tgccggtaaa ttacgaaagg tcaatatttc aaaaggaaat tttcgatttg ctccgctgat
    35941 gtatttggaa gcagcgttac agagcataga caaaatgcca cagtcaactt ttgatgaaat
    36001 tgtcgaaaaa tatgttgaaa tgaacgtggc tcatccattc cgagagggga atgggagaag
    36061 cacgagaata tggcttgatc tgatgttgaa aaaagaaatc ggctgtgtgg ttgactggag
    36121 caaggtgggt aaagaggatt atctgcttgc catggagcga agtcctatca aagatatcga
    36181 aataaagttt cttctgaaaa atgcccttac agatgatgta aataaccgag aaatttatat
    36241 gaagggcatt gatcacagtt attactatga aggctattat gtgtttaaga cggaagattt
    36301 gacaggcaca aaggagtaac ttgatttagc attagaaaat cggaggaata cggatgcagt
    36361 atctttcagc tgccaaaata acagagaaat ggaatatatc ggaacgcagt gtacgaaact
    36421 actgcgctca taatcgtgtg gaaggagcgt tcatca
//
LOCUS       DBMDUW010000024        33515 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1038_length_33515_cov_4.022476, whole genome shotgun sequence.
ACCESSION   DBMDUW010000024 DBMDUW010000000
VERSION     DBMDUW010000024.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 33515)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 33515)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33515
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1038_length_33515_cov_4.022476"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..210
                     /locus_tag="ACZPCR_06350"
     CDS             <1..210
                     /locus_tag="ACZPCR_06350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574300.1"
                     /note="with RbsBCD acts to import ribose into the cell;
                     RbsA contains 2 ATP-binding domain; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose ABC transporter ATP-binding protein"
                     /protein_id="HIR1230532.1"
                     /translation="DVKTKADIYHLIDRLTAEGLSVIFISSEMPELINMCDRIVVMNH
                     GRTTGVLSREEFTQERIMELSTKEL"
     gene            224..1213
                     /locus_tag="ACZPCR_06355"
     CDS             224..1213
                     /locus_tag="ACZPCR_06355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1230533.1"
                     /translation="MKHKWGQSAVNTIKMNFGILMGLLILCVGLTFLTDKFATVTNFF
                     NVIRQITINLYLACGMTFVILLGGIDLSVGSVIAVSGCISAGMITWLGLPVPVGILIG
                     VFFGTLIGAFNGLVVSRTTIPAFIVTLAAMNIGRGIARIYTHAQTIAVLDDAYTFWGM
                     GEILGLPIQLYLIIAVIIVSSFILNRTKLGRHIYAVGGNKTAAEYSGINVKKVTFFVF
                     AFSGFLASLAGVLTVGRTFTATMIMGDSAEMDAIAAVVLGGTSMSGGKGSISGTVIGV
                     IVIGILKNGMNLLGIDSSWQYVVQGIVILIAVYIDFIKSGGTASDLIRKLKRA"
     gene            1267..1818
                     /gene="hxlB"
                     /locus_tag="ACZPCR_06360"
     CDS             1267..1818
                     /gene="hxlB"
                     /locus_tag="ACZPCR_06360"
                     /EC_number="5.3.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0043800 - 6-phospho-3-hexuloisomerase
                     activity [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-3-hexuloisomerase"
                     /protein_id="HIR1230534.1"
                     /translation="MGYTRKTEEVLGELSRALRGIDEKEVTGMVACLNRENRIFCDGA
                     GRSRLQAEGFAMRLAQMGFLASVVGEATAPAITQNDILIILSGSGETPVLLEHGKKAK
                     KAGALVLAITASPHSSLSELCDVSVIVKADRKDQAGGCSMQPMGTLFEQSAGILCDTM
                     VLLLMDRFHITGEEMFRNHSNLE"
     gene            1895..2731
                     /locus_tag="ACZPCR_06365"
     CDS             1895..2731
                     /locus_tag="ACZPCR_06365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HIR1230535.1"
                     /translation="MGNTDSRIRIGAVAWGLPGGGSYSVRTAHEAGLSGIQLELGSFE
                     AGYPLAQKTVMEGYLEDGERYGIEFPALVLNDLMEHEFIHGNSTENGKIAWEQMEIGV
                     ETAAQMGIRRLMIPNFIHNLITCEEHIEHAREALSYACRLGAEQGITILTENALDWKR
                     QIELLDAVGADNLKIHFDTQNFKFNFDMDQLSQLEGLYPYMDTILHVKDGTDAPGNRL
                     LGEGNTDFFSQMKYLKERGFEGWIITENYYNLLPLRNQARSGGQMELLLRDVNTIQGC
                     FA"
     gene            2863..3942
                     /locus_tag="ACZPCR_06370"
     CDS             2863..3942
                     /locus_tag="ACZPCR_06370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007863818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HIR1230536.1"
                     /translation="MTFDQIIIWVIAAGAVIGAADKIFGNRLGLGRKFDEGFQAMGPL
                     ALGMVGIVCLAPVIADVSGPVIIPIFEALGADPAMFGAVLANDMGGYSLAVELAENQE
                     AGLLAGTIVSSMLGCTLVFSIPVGLSLIEKEDRPYFSRGFLIGLITIPAGSVIGGLAA
                     GFELSMVLRNMVPVILLAAVLALGLKAFPEAMVKGCMIFGQLITIVIYIGLAAAAFEH
                     LTGAVVIPGMADIMEGMRAVAGIGIVLIGTFPALTILTKLLDKPLNRAGRKLGLDKTS
                     AAGLVFTLANSVPVYTMMKNMNKKGIIVNTAWLVPATSALGAHLGFTAGVEPSMITPV
                     VAGKLSAGVLAVCLALFMCRDMEEA"
     gene            3980..4681
                     /locus_tag="ACZPCR_06375"
     CDS             3980..4681
                     /locus_tag="ACZPCR_06375"
                     /inference="COORDINATES: protein motif:HMM:NF019349.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HIR1230537.1"
                     /translation="MTHKDQTPLAQIAAEKIIEMIREEKLQPGDRLQNEYDLAKRLEV
                     GRSTVREAIKSLETRNILTIRRGAGTYLSSREGVAEDPLGIALMGKDEEIALELLEVR
                     MILEPESAAMAAVHASKEEKAAIRRQNRRVTAMIEQGLNHTEEDSKFHQLIAKATGNR
                     IIAKLIPIIYRSVSLTIEMTNRRLSETTILFHEQIVDAIERGDERGARSAMVAHMSEN
                     RLYIIKEIERKNRFQ"
     gene            4974..5990
                     /locus_tag="ACZPCR_06380"
     CDS             4974..5990
                     /locus_tag="ACZPCR_06380"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008398891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase"
                     /protein_id="HIR1230538.1"
                     /translation="MKALVYAGPKKAELRDVETGEKKEGQIKIDVTYCGVCGSDIGIY
                     LGTHPRAKAPLVFGHEFLGVAAEDGKRIKKGDRVVPYPLLSCGHCKACRNGNEHVCNT
                     LGLIGIDVDGGMCESVYVDEDVLYKVPEGVSDKAAAVIEPLAVLVHAIHMSGFEPLDT
                     AVVAGAGPIGMLCAVMLKHAGASQIFISDVAEKRLEAARELGMIPVNPLKEDLEAVVK
                     AATDGEGCDVFFECSGAAAAAVQMTDVTRVRGKICMVSVHKQPHEVNLRDVNFKEQTL
                     VGTRVYTKDEFGQAVELTKKLESQLEKIVTHVVPLRESEKVFDMIADPECGTIKVVVD
                     CKAV"
     gene            6016..7062
                     /locus_tag="ACZPCR_06385"
     CDS             6016..7062
                     /locus_tag="ACZPCR_06385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004607462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DctP family TRAP transporter solute-binding
                     subunit"
                     /protein_id="HIR1230539.1"
                     /translation="MKQRGKAVTAGCILLALLAGVGFTKAGSKYRTQEEVNLIFSNVT
                     SNSAKQAAEKFKELVEEYSGGKMTVDVFQDNQLGDDKTAAEGVQNGDIDIAVSSTSSL
                     STLYKDYYLYDTPYLFLNKEEVYDVGFTGETATKMLEGVEKVGLKHMAMWENGFRNYT
                     NNAHPIESPADCKGQKIRTMENPIHMKAWKEIGANPTPMAFSELFTAMQQGTVDGEEN
                     PIGIISSNRFYEVQKYISLTQHVYTPYVVVMNPDKYDTLTKEQQEIVDRAMKEATQFQ
                     LEQSAKDEEEGIKIMEDYGCEVNELTDEQKMEFQKIMEDADVFGVAKDAMENPEYFDG
                     ILKELEEYRAEGEQ"
     gene            7066..7566
                     /locus_tag="ACZPCR_06390"
     CDS             7066..7566
                     /locus_tag="ACZPCR_06390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004607463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015740 - C4-dicarboxylate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HIR1230540.1"
                     /translation="MKKGLQFLNRYLEEILCVALMSVMTIIIFVQVIMRYVAHNSLSW
                     SEELARYCFIWLIYIGVAYGCKLMKHIKIDAALYLFPKKLRPYITILGELLVLMFAAY
                     IVVTGVELTYKQWVFGKVSPALGLPLQYINAAPVVGFGLVIIRQIQNIWYLAGNLGKT
                     EEGGEE"
     gene            7566..8846
                     /locus_tag="ACZPCR_06395"
     CDS             7566..8846
                     /locus_tag="ACZPCR_06395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004607464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HIR1230541.1"
                     /translation="MVAIVLFGTLVIALILNMPVGIAIGLSSLCAVLADGRLSSLYIV
                     QQLVTSADSFPLMAIPLFILAGELMGAGGVSKRLLNVCNVFLGRFTGGLATVTVVLCM
                     FFAAVSGSGPATVAAIGSMVIPTMLQKGYSKSFTLALIATAGSIGVIIPPSIPMVVYG
                     VSTSTSISSLFMAGFLPGLLIGSSLILMSYIYCRRHGWKGDDRRYTFREKMEAIWDAK
                     WALINPIIILGGIYAGVFTPTEAAAVAAVYAFICGVFIYRELDFKQLFGTLGSACSTT
                     GTTMVIIGCATAFTRILTIEKIPDTITTGILNFSDNMIVILLLINLLLLVVGCFMDTT
                     PAMMVLSPILLPIAMQFGVDPIHFGLIMVVNLAIGFITPPLGINLFVAARVGGSSLET
                     VCSGIIKFILVMILDLLLITFIPGISMILPNTFM"
     gene            8874..9638
                     /locus_tag="ACZPCR_06400"
     CDS             8874..9638
                     /locus_tag="ACZPCR_06400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007860981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HIR1230542.1"
                     /translation="MNLFDLTGKTAIVTGGTRGLGHGMAEGLLEAGCRVAVIGTGDSV
                     FERAEEFRERGYFCEGVKADLGCSEERKRAFDECVQKLGGRLDILVTAHGIQRRHPSE
                     EFPMEDWEQVLGVNLTAVFELCQLAANQFLSQKSKGKIITVSSMLSFFGGYTVPAYAA
                     SKGGVAQLTKALGNEWAGKGICVNSLAPGYMATDMNTALMDPDNPRKKEITDRIPEGR
                     WGTGEDMKGPCIFLASDASDYLSGAVIPVDGGYLVR"
     gene            9667..10620
                     /locus_tag="ACZPCR_06405"
     CDS             9667..10620
                     /locus_tag="ACZPCR_06405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009290140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003682 - chromatin binding [Evidence
                     IEA];
                     GO_function: GO:0003714 - transcription corepressor
                     activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA];
                     GO_function: GO:0140297 - DNA-binding transcription factor
                     binding [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C-terminal binding protein"
                     /protein_id="HIR1230543.1"
                     /translation="MKVIITDCDHDNIEIEKKIFADAGIEMELKHAISEDEVIEQCQD
                     AEILIVQYAKITRKVMEHCPRLKFVVRYGVGVDTIDVAAAAEFGVQIGNVPDYGMNEV
                     ADHAIALALSMTREIVKMNQFTKNEKWDYTKAIPIHRFSNLTVGVIGLGRIGRNFAQK
                     MHALGFQVIGTDPYFSPTEETNAYVKAVSMDEVIETSDIISLHCPADGNRDLFCKETF
                     KRMKNTAVLINVARGGIINETDLDQALTDGEIAGAALDCMAGEPVSKDSPLFAHENLL
                     VTPHMAWYSEEAAQELKRKVAEESVRFARGEKIHYPINKLA"
     gene            10634..11602
                     /gene="eda"
                     /locus_tag="ACZPCR_06410"
     CDS             10634..11602
                     /gene="eda"
                     /locus_tag="ACZPCR_06410"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008976435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008675 -
                     2-dehydro-3-deoxy-phosphogluconate aldolase activity
                     [Evidence IEA];
                     GO_function: GO:0008700 - (R,S)-4-hydroxy-2-oxoglutarate
                     aldolase activity [Evidence IEA];
                     GO_process: GO:0009255 - Entner-Doudoroff pathway through
                     6-phosphogluconate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HIR1230544.1"
                     /translation="MHEVLKKVEQFGVVPVIKIEDANDAVPLAKALCEGGLPCAEVTF
                     RTEAAEAAIQAMREAYPDMLLIAGTVLTKEQADRAVSAGAQAVVSPGFNRKVVDYCVR
                     KGILILPGCSCPSDMEQAIEAGLSAVKFFPAEASGGIKAIQAMAAPYGQLRFMPTGGV
                     NAVNMQEYLKNDKVLACGGSWMVPEKLIQEGRFEEIRQLTKEAVLAVHGFALAHVGIN
                     SADEEEARKTAQTFERLFGFESHENPSSIFSASYVETIKKPYLGAKGHIAIAVHSVER
                     AKAYLERMGTEFLEDSAVYRPDGRIQAVYLKEEIGGFAVHLVRRAV"
     gene            11631..12587
                     /locus_tag="ACZPCR_06415"
     CDS             11631..12587
                     /locus_tag="ACZPCR_06415"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009290138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HIR1230545.1"
                     /translation="MGKTILFGEPMALLIADTTGPLEEVEHFTRALSGAEVNVSIGLS
                     RLGHPVEYLTRLGDDPFGHYIENQLKKNEIGTSMVTYDPVYRTGIQLKNRVTDGSDPY
                     APYYRKGSAASHISKAEIDALDLTDVELIHVTGIPPALSESAREASFCLMKRAREAGI
                     FLTFDPNLRPALWENEETMIRVINQLASMADAVLPGIGECRILAGTDQPEEAADFYQN
                     LGVKTVIVKNGADGAYVREGEASYCVPGYRVEKIVDTVGAGDGFAVGVLSGMLERLSM
                     RDSVLRGNAIGAIQVMNISDNEGLPTQEELRKFQTGTKAQIL"
     gene            12670..13461
                     /locus_tag="ACZPCR_06420"
     CDS             12670..13461
                     /locus_tag="ACZPCR_06420"
                     /inference="COORDINATES: protein motif:HMM:NF012669.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HIR1230546.1"
                     /translation="MLQSRREKIAEMIQADRVLKVSDLMRQFDVSIETIRRDLEYLEK
                     QGLLTRVYGGAVLNQKKGKEPLYEQREIKHYAEKAAIAQRAVELIEDGDVLGIDIGTT
                     AREFAKALIGKKKVIVLTNSMPIAEILSEDENIRVIMLGGEVRKGEFSVSGFVAEQVM
                     SRFNLDKYILGIGGLTVENGITDYHIEETNLRRVMLERSQKVIGLTDYSKFGVIAMNE
                     VCPLSRLDVLITDSRADRMIIGKMHTMKTEVIQIEAPGEQPDTEQ"
     gene            13852..14952
                     /locus_tag="ACZPCR_06425"
     CDS             13852..14952
                     /locus_tag="ACZPCR_06425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012200648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HIR1230547.1"
                     /translation="MTFDQIILWVMAAGVLIGAADKIFGNRLGLGEKFDEGFQAMGPL
                     ALGMVGIVCLAPVIADLLGPVIIPVFEALGADPAMFGAILANDMGGYPLAVELAQDQE
                     AGLLAGNIVASMLGCTLVFSIPVGLGLIEKEDRPYFSKGLLIGLITIPAGSVIGGLIA
                     GFDPSMVLWNTVPVIILAAVLALGLKFIPEAMVKGCMVFGQFITIVIYIGLAAAAFEH
                     LTGVVVIPGMADIMEGMSAIAGIGIVLLGTFPVLTILTKVLDKPLNRAGQKLGLDKTS
                     AAGLVFTLANSVPVYTMMKDMNKKGIIVNTAWLVPATAALGDHLGFTAGVEPSMITPV
                     VVGKLAAGVIAVCLALFMCRGMEQEHNRQQPE"
     gene            15035..16531
                     /gene="glpK"
                     /locus_tag="ACZPCR_06430"
     CDS             15035..16531
                     /gene="glpK"
                     /locus_tag="ACZPCR_06430"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009263020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HIR1230548.1"
                     /translation="MEKYYLGLDQGTTGTTALIFDSQWNQIARGYKEHTQYYPKPGWV
                     EHDPMEIWNSILETIAMAAEEAGIQVADLTCMGLDNQGETVMLWDRYTGVPVYNAIVW
                     QDRRTAKMADELAEKYGDLIRERTGLVADAYFSATKIRWIMDHVERVREKIENGHVIA
                     GTLDTWMIWKLTHGHVHVTDYSTASRTMLLNIHTGEWDDDILKALGIPKKILPEIHDS
                     AEVYGYTDPLDFFGALIPISGSVVDQQAALFGQACFKPGTVKTTYGTGCFMLMNTGDK
                     PVYSENGLLTTVGWGLNQKQMTFALDGGIYISGAAVQWLRDKLHLIASAAETEDLAKS
                     VPDTGGVYFVPAFAGLAAPHWDQYARGTIVGITGGTTKEQLVRATLESIAYQVKDNLD
                     VMVKDSGIPIEVMRVDGGAVVNEFLMQFQADILGIPVDVPVITDTTGLGAAYLAAYGI
                     GEFHDLSELEHNWKLYKRYEPHMEESVRAELLRNWHRAVERAKSWAEK"
     gene            16557..17993
                     /locus_tag="ACZPCR_06435"
     CDS             16557..17993
                     /locus_tag="ACZPCR_06435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HIR1230549.1"
                     /translation="MRTNVVVIGAGAVGCAVARELSKYKIDVVVVDKNEDIGGDASKS
                     NSAIIHTGYDASPGTLESQLVVAANPMYDELARDLDVPFKRIGAILPAITQEQYEKLP
                     EIKAKAFKNRVYDVEYKTGEELLAMEPNLNPEVKGGLYIPRESIIDPFILVQALAENA
                     NENGVSFLLNTKVTGIQTENGKVKAVETTGGIIETDYVINAAALYCDEIAAMVGKADY
                     KVVARRGQFYILDKNTSCQVEHIVLPIPTKVTKGKLMCPTIHGNMLVGPTAEDLDNKT
                     DKSVTPEGLQSIVDDVKRLIPNVNVRDTITQYSGLRPNRNPEGLHVDMWEDLEGFVNL
                     SGVRSTGLTLSVAMGKYVAQLLIDHGAPLVFKENFKKTRKGIVRFHELSREEKEKLIK
                     ENPAYGTVICRCETITEGEILDCIRRPLGARSMDAVKRRVRAGMGRCQGGFCGPKVIE
                     ILAKEWNIPVEQVNKNNAGSYMVTGRMR"
     gene            18040..19341
                     /locus_tag="ACZPCR_06440"
     CDS             18040..19341
                     /locus_tag="ACZPCR_06440"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007863823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HIR1230550.1"
                     /translation="MYEITCDVAIIGAGPAGLSAAVAAKKEGAERVLLIERDESVGGI
                     LQQCIHPGFGLTYFKEELTGPEYAGRFEDEAEKLGAEVLLNSMVLEVVPEENVVYCVN
                     SRYGMTRVRAGSIVLAMGCREKTRAGIQIPGTRPAGVYTAGAAQRLINRQNAMVGREV
                     VILGSGDIGMIMARRMSLEGAHVKAVVEIMDFLAGLTRNKVQCLDDFDIPLKLSHTVT
                     RIVGNERVEGVYVAAVDENKKPILETEEFISCDTLLLSVGLLPENELTRQAGIEMNPV
                     TNGPSVNQYMQTSAPGVFACGNVVHVNDLVDNVTTESMQAGACAARYAALWKDGAVQG
                     EMAGERNSVKAVPGSNVRYLCPQSICLDSSLKRNSENETVRLFFRVLAPDTEVKITAK
                     CGEKEIKEKKALRVNPGEMESIEIPLHLVTGDVTVEIEKEA"
     gene            19346..19702
                     /locus_tag="ACZPCR_06445"
     CDS             19346..19702
                     /locus_tag="ACZPCR_06445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007863825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1667 domain-containing protein"
                     /protein_id="HIR1230551.1"
                     /translation="MTKEIICTVCPMGCHILVEGEGDQVTSITGYTCRRGEEYGRQEF
                     SHPVRILTTTVKTDSEAHPLLPVRSSRPVPKELLAQCMEEIRKKKVTAPVRRYDVIIE
                     NICGCGADIVASGEIR"
     gene            complement(19807..19962)
                     /locus_tag="ACZPCR_06450"
     CDS             complement(19807..19962)
                     /locus_tag="ACZPCR_06450"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230552.1"
                     /translation="MKDMKTVIIAVLCGVIAGLALILKKQQDIQMVLALSHRELESWL
                     DEGKRVK"
     gene            complement(20093..21313)
                     /locus_tag="ACZPCR_06455"
     CDS             complement(20093..21313)
                     /locus_tag="ACZPCR_06455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007882086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HIR1230553.1"
                     /translation="MYCVRKVTDDIYWVGANEHRLHLFENIHPIPRGVSYNAYLLLDK
                     KTALFDTVDWAACRQLLENLDHLLNGRPLDYLVINHMEPDHGASIEEVLLRYPDVTII
                     STEKSFMLMRQFGFAVDSHPLMEVKEGDSISFGKHTVQFIAAPMVHWPEVMVSFDSTD
                     GVLFSADAFGSFGALDGKLFADEVNFDRDWIDDARRYLSNIVGKYGPHIQLLLKKAAG
                     ILDQIHYICPLHGPVWRKDLGYFIDKYDKWSRYEPEEKGVMIAYASMYGNTEAAAQAL
                     ASRLCERGCTNVWMYDVSNTHISQLISESFRLSHIVLASVTYNLGIYPVMHNYLMDMK
                     ALNLQNRTFALIENGSWACKSGDLMQKFINEELKNMTVLNERLSLASSLLPDKAAELD
                     MLADAIAESVKAAK"
     gene            complement(21332..23242)
                     /locus_tag="ACZPCR_06460"
     CDS             complement(21332..23242)
                     /locus_tag="ACZPCR_06460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HIR1230554.1"
                     /translation="MLFHTTAEHEALRAKIRAFAEEEVKPHAFLMDKENRFPDEAVKK
                     LGEMGLMGIPYPKEYGGAGLDVISYAIAVEELSRVDGGTGVILSAHVSLGSWPIFAFG
                     TEEQKKKYLVPLCRGEKIGAFGLTEPNAGSDAGGTETTAIDKGDHYLLNGGKIFITNA
                     PKADTYVVFAVTTPDIGTRGISAFIVEKGWKGFTFGDHYDKMGIRSSSTAELIFNNVK
                     VPKENLLGKEGQGFKIAMATLDGGRIGIASQALGIAQGAYESALDYAKERVQFGKPIG
                     FNQAIGFKLADMATKLRCARFLVYSSAELKEHHEPYGMESAMAKMYASDIALEVTNDA
                     VQIFGGTGFLKGMDVERMYRDAKITTIYEGTNEIQRVVISSALLGKPPKDASGSSSRP
                     KKPAPVTGVRKRHMITEGSPKEQATELAALLRKDGYDFTVGIPMDTPIIQAERVVSAG
                     QGIGEKENMKLIEQLAKAAGAAVGSSRPVAETLKYVPLNRYVGMSGQKFTGNLYIACG
                     ISGAVQHLKGIKDASTIVAINTNGNAPIFKNCDYGIVGDVKEILPLLAEELGLEEKKP
                     APPMVKIKRPLPPKPEPIGKRYVCGGCGYEYIPELGDEDGDIAPGTLFEKLPEDWVCP
                     ECAESKEMFIEA"
     gene            complement(23486..25261)
                     /locus_tag="ACZPCR_06465"
     CDS             complement(23486..25261)
                     /locus_tag="ACZPCR_06465"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007717853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HIR1230555.1"
                     /translation="MYAKKEKDRSRLMKAALQEIPCDLTVSNVRYLNIFTGEIYPAQV
                     DILDGVVVRVREEGQETACPSREIYDGKDAYLIPGFIDVHMHVESTMMIPEQLSRAVL
                     PWGTTTICTDPHEIGNVMGIEGVEFMLENAKKSALRQYVLAPSCVPAVPGLESSGASF
                     EAPEIRTLLEKEGVIGIAEIMDFVGVYKDSPRMHAIIDEGLKKNAFLQGHAPTVTGRE
                     LCAYRLGGPESDHESQSAAEVREKLRLGMHVNVRGSSLCDVVPDLIRGLDGHRWYDHV
                     SFCTDDVHASDLLADGHVNRVVKRAVAAGMSSLDAIKCATLNAAKELGIQDLGAVAPG
                     YVADFQLVRRLDGSQPEAVFMEGRKVAENGVYTGCDPEPAASSFKNTVNIPQISSAAD
                     FILTVPENYAKDTIEVNVMVPSADKILRTVRPVSLPVRDGAVSLEGREDLQFVSVVNR
                     YGNGKQVIGVFENFGLCEGAFATTITHDSHNLLVVYRDPESALKAVQALQACGGGICA
                     VKDSKASVLELPVAGLMSNLPCRQMAERIETVQKAVQEITTPETSLLGASIMSLTALP
                     GVTITDFGLVDGISQTLLPVFPSER"
     gene            25606..26667
                     /locus_tag="ACZPCR_06470"
     CDS             25606..26667
                     /locus_tag="ACZPCR_06470"
                     /inference="COORDINATES: protein motif:HMM:NF012742.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HIR1230556.1"
                     /translation="MEQKSTLRDVAQLAGLSAGTVSKYLNHPESVQEKNRKKIEKAIR
                     LLNYTPNVLARKLASGRSRVLGLCIVTEPEISDSTWLHLLPMIQTLNDSACQAGYQLQ
                     IGLSSVGREEQTLQMLRDGAEGKGMDGLFLVSAWEVPEDLIRYLLNREFPFVLVENHS
                     RCLENRQFYFDNYGIGVSCTEYLSGLGHREIGFFHAGGSQQHMADRYQGYLDTLKRLG
                     LPWKEEFTRYGDYSIESGFCCMEELFSMECRPTAVICGNDNMAAGALQFLRKRGLSAP
                     ETVSLIGVDDSIAARAASPALTSVHLPMAQVAKEAAQALIRQIEEGKTAESRKFSCRL
                     VERESTAPGVSQAAGNSKR"
     gene            26687..28015
                     /locus_tag="ACZPCR_06475"
     CDS             26687..28015
                     /locus_tag="ACZPCR_06475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015851 - nucleobase transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HIR1230557.1"
                     /translation="MKMEEFFKLRERKTDVKTEILAGITTFMTMAYVLAVQPSAIVGF
                     GDAASLTDANGYVISKSAILIMCALVSGVITIFMGLYANFPFALSTGMGTNFLLGALL
                     QDGSLSFGSIMSIILISGIIFLALTIFGIRDMIVKMIPKNIKVAISASIGFFVAYLGF
                     KNTGIGTFTDGIAMGDFTDPKVLLAIAGLLLISILTAYNVRGAILIGIIAITIAGIPF
                     GVTKLPEHFFEIPDMANLGNVCFNFDFKHLLTADTVIWVFVAFFGDFFSTLGTVLGVA
                     GKARMLDEDGNLPGIEKPFLVDAIGTCVGAVTGCTTITTFVESTSGVEAGGRTGLTAV
                     TTGIIFLLTIFAAPLFVIIPDAATGPALIFVGFLMISGFSEIDFSNFDDAFGPFIMIV
                     FGTYTANIATGIAAGILAHVGIKAATRKWKEIHPGLYILCIPLILYFIYN"
     gene            complement(28114..29481)
                     /locus_tag="ACZPCR_06480"
     CDS             complement(28114..29481)
                     /locus_tag="ACZPCR_06480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015520320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1230558.1"
                     /translation="MKHAVRASSKKPHLYSNRQLIALMLPLICEQIFTSFMGTVDSMM
                     VSNVSEAAISAVSLVDSINILVIQAFYALASGGAIVCANYLGQKRRDQAERSANQLLF
                     IIFAISLAVLAVCQLFRAPLLRLVFGSVEQEVMDAAMVYFFYTSLSFPFIALFDSGSA
                     VFRAQNNSRLPMAITVSTNLMNIAGNALLIWGFHLGVAGAAVSTLLSRIAAALLVLLF
                     LRRKSGELRIGNFIFLKPDGRLIKNILRIGIPSGVENGMFQFGKLAIQSTVSTLGTTA
                     IAAQAMTNIMENFNGIAGIGIGIGMMTVVGQCLGAGRPDEARYYIKKLSFAAEFVVFG
                     SCLLIFLMAGPITKLAGLSGESASLCLFMNSWITIVKPLVWTAAFIPGYGLRAAGDVK
                     FSMILSCLSMWICRVSLCIYLIRVCGFGPIAVWIGMFTDWTVRGLFFIHRFRSGKWLN
                     HQVTD"
     gene            29710..30708
                     /locus_tag="ACZPCR_06485"
     CDS             29710..30708
                     /locus_tag="ACZPCR_06485"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230559.1"
                     /translation="MKMKRKHLLCCLTVAAMLGGCGPESLEKTPQERQTQTADMAQNG
                     KRESGTKRETSGNEGQSEREENSQFADGFGLIEEESPRVYQLAEEDTPFTESALARAD
                     LVFAAQQEGKFWFTAVITDYSVEEADEETAPREIDHNPAYFKIEETGESGQETFYGYS
                     PYLERINDTEQTEPVRIEGTNIEKAGYAPGRLVQKTSSLSRLPSGSFIMNFGYFMEDF
                     YSCPGEPEGEYRLYLPGFENPIVFEMEAAPALEGKQEHSEKAVSESSSAWEELGKGIS
                     GTAEGDGYKRGKTHTAGRRNRQMEAQVESRECRSYLRCRRKPGRSFRREKRDISRR"
     gene            30630..31181
                     /locus_tag="ACZPCR_06490"
     CDS             30630..31181
                     /locus_tag="ACZPCR_06490"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230560.1"
                     /translation="MQIVFEMPEEARKELQTGKAGHFQAVMEGITLVGADESQMVNIP
                     VPSPGETRTLEQTVSFRDCQIRLLKVAAQERTEEEKKESGTDADVLLHVSASVTDRSE
                     GQTFTFAQIEWEGERKTVSYARTGWPEFPDEGGGVQPETVMTGFSLLSSGSEESVSAR
                     IYAPSYWLPETVIIPLKIDNLNL"
     gene            31445..32878
                     /locus_tag="ACZPCR_06495"
     CDS             31445..32878
                     /locus_tag="ACZPCR_06495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HIR1230561.1"
                     /translation="MENSKKIDWYTLSFMAFSTVWGFGNVLNGFVYFNGIEVIFSWIL
                     MFVLYFIPYTLMVGELGSAFKHSGGGVSSWIRETINPKFAYYAGWTYWACHVTYIASK
                     GSGGLKALSWMVFQNGSTYDQFPTLWVQMATLAVFLFFCWVASRGLNPLKKLATLAGT
                     SMFIMSMLYILMMFAAPVINPNGGYVSMDFSVKNLIPQFNVGYFTSLSILVFAVGGCE
                     KISPYVNKVKNSATGFPKGMIALAIMVMVCAILGTIAMGMMFDPAIINESKESFDSYV
                     SNGSYWAFQKLGEYYHVGNLFLIIYAACNAVGQFSTLVLSIDAPLRMLLDNEDAREFI
                     PSKLLKKNKYGAYINGIWMVVVLSGTIILVQSFVPGAAAVLSQLNKLNSVTMPLRYLW
                     VFAAYIALRKYVGKFTPEYRFTKNQGLAFTAGIWCFAVTAVCCVMGMYVEGDMASTAL
                     NIITPFILTALGLILPIIKKRETERAS"
     gene            complement(33032..>33515)
                     /locus_tag="ACZPCR_06500"
     CDS             complement(33032..>33515)
                     /locus_tag="ACZPCR_06500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004845336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="ANTAR domain-containing response regulator"
                     /protein_id="HIR1230562.1"
                     /translation="VHTVSSINAARCTLTEKTYDFIIINAPLRDDIGVRFAIDTCCNK
                     QSVVLLIVKSDIYNGIHEQVTEYGVFTLSKPLSKITMTYALNWLESSRERLRQFEKKS
                     LSIEEKMDEIRLVNKAKWILISQLSMSESEAHRYIGKQAMDRCVTKRTIAEEIIKTYS
                     "
BASE COUNT         8764 a         7276 c         9706 g         7769 t
ORIGIN      
        1 gacgtaaaga caaaggcgga tatttatcat ttaattgatc gcctgacagc ggagggcctg
       61 tctgtgatct ttatttcttc tgagatgcca gagcttatca atatgtgcga ccggattgtg
      121 gtgatgaatc acggaaggac gacaggtgtg ctttccaggg aggaatttac ccaggagcgt
      181 attatggaat tatccacaaa ggaattgtaa agaggtgaca aaaatgaagc ataaatgggg
      241 gcagtcagca gtaaacacaa ttaaaatgaa cttcggcatt ctgatgggcc ttttgatcct
      301 ctgtgtggga cttacgttcc tgacagataa atttgctaca gtaacaaact ttttcaatgt
      361 cataagacag attacaatca atttgtatct ggcctgcggc atgacttttg tcatcctttt
      421 aggaggcatt gacctgtcgg tgggttctgt cattgctgtg tcaggatgca tcagtgcggg
      481 catgattaca tggctgggac tgcctgttcc agtgggaatt ctgattggcg ttttctttgg
      541 aaccctgatc ggagcattta atggactggt agtttccaga actacaattc cggcctttat
      601 tgtgacgctg gcggcgatga atattggccg tggaattgcc agaatttata cccacgccca
      661 gacaattgcc gttttggacg acgcatatac cttctgggga atgggagaga ttctgggact
      721 ccccattcag ctttatctga ttattgccgt tattattgta tcttccttta ttctaaacag
      781 gacaaagctg ggacgccaca tttatgcggt aggaggaaat aaaacagcgg cagagtattc
      841 aggaattaat gtaaaaaagg ttacattctt tgtgtttgcc ttcagcggtt ttctggcgtc
      901 tctggcagga gttctgacag taggaagaac ctttacagct acgatgatta tgggagacag
      961 cgcagaaatg gacgccattg ccgcagttgt gctgggagga accagcatga gcggaggaaa
     1021 gggaagcatt tccggaacag tcattggcgt aattgtaatc ggtattttga aaaatggaat
     1081 gaatctgtta ggtattgatt cctcctggca gtatgtagtt cagggaattg taattctgat
     1141 tgccgtttac attgacttta ttaaatcagg aggaacggcc tctgatttaa ttcggaaact
     1201 gaagcgggct tagagtgcag ttcggaacga tattgagata gaggaagtaa aagaggaaca
     1261 tgcagaatgg gatataccag gaaaacagag gaggtgctcg gagagctgag ccgggccctt
     1321 cgaggaattg atgaaaaaga agtaactgga atggtagcct gccttaaccg agaaaaccgg
     1381 attttctgcg atggggctgg aagaagccgt ctccaggcgg aagggtttgc catgcggctg
     1441 gcccagatgg gatttttggc cagcgtggtg ggagaagcga cagctccagc cattacccaa
     1501 aatgatattt tgattatact cagcggttcc ggagaaacgc ctgtgcttct ggaacatgga
     1561 aaaaaagcca agaaagcagg agccctggta ctggcgataa cggcgtcgcc tcattcctcc
     1621 ctgtcagaat tgtgcgatgt ttctgtaatt gtaaaggcag acagaaagga tcaggcggga
     1681 ggctgctcta tgcagccgat gggaacgctg ttcgaacaga gtgcaggaat cctttgcgac
     1741 acaatggtac ttctcctgat ggatcggttt catattacgg gagaagaaat gttcagaaac
     1801 cacagcaatt tagagtaatc ggaattagaa taaaagcatg ggaatggaaa tcaggaaaag
     1861 gattaagcaa gaagatggga ggcgcaggaa atatatggga aatacagaca gcagaattcg
     1921 aatcggagcc gtagcctggg gacttccggg aggcggctcg tacagtgtca gaactgccca
     1981 cgaagcaggc ctttcaggaa tccagctgga actgggaagt tttgaggcag gatatcctct
     2041 ggcccagaag acggtgatgg aaggttacct ggaggatgga gagcgatatg gaatagaatt
     2101 ccctgccctt gtcttaaatg atctgatgga gcatgagttt attcatggaa attctaccga
     2161 gaatgggaaa attgcctggg agcagatgga gatcggtgtg gagacggcgg cgcagatggg
     2221 aatccgccgt ttgatgattc ctaattttat tcacaatctg attacctgtg aggagcatat
     2281 tgaacatgcc agagaagctc tcagctatgc gtgccgtctg ggcgcagagc agggaattac
     2341 aattttgaca gaaaatgctc ttgactggaa aagacagatt gaacttctgg atgcagtagg
     2401 cgcagacaat ctgaaaattc actttgacac ccagaatttt aaatttaatt ttgatatgga
     2461 tcagctcagc cagctggaag gactgtatcc ttatatggac acaattcttc atgtaaaaga
     2521 cgggacggac gctccgggaa atcgtctgtt aggagaagga aatacagatt tcttcagcca
     2581 gatgaaatat ttgaaggagc ggggatttga aggctggatt attacagaaa attactataa
     2641 tctgctgcct ctcaggaacc aggcccggtc aggaggccag atggaacttc ttttgagaga
     2701 tgtgaatacg attcagggat gcttcgcgta gagaattttg ccgtataggg aaacctgtac
     2761 ggcatttttt tgccattccc tgcggttggc aaatgtcttc taaggtatta taatgaaacc
     2821 tgatataagc gccgggcagg cgtgagagag ggaggagatg gaatgacatt tgaccaaatc
     2881 attatttggg taatagcagc cggggcagtc atcggagcgg ctgataaaat ttttgggaac
     2941 aggctggggc tgggccggaa gtttgacgag ggatttcagg ctatggggcc gctggccctg
     3001 gggatggttg gaatcgtctg tctggctcct gtgattgcgg atgtgtcagg ccctgtgatt
     3061 attccgatat ttgaggcgct gggagcggat ccggccatgt ttggagcggt tttagccaat
     3121 gatatgggcg gctattctct ggctgtggag ctggccgaaa atcaggaggc gggactttta
     3181 gctggaacga ttgtatcctc catgctgggg tgtacgctgg tgttttccat tcctgtaggc
     3241 ttgagtctga ttgaaaagga ggatcgccct tatttttcca ggggattttt aatcggtctc
     3301 atcaccattc cggcgggaag cgtcatagga ggcctggccg caggctttga gctgtccatg
     3361 gtgcttcgga acatggttcc tgtcattctt ctggcggctg ttctggctct ggggctgaag
     3421 gcgtttccgg aggccatggt aaaagggtgc atgatattcg gacagttgat tacgattgtc
     3481 atctacatag ggctggcggc agctgccttt gaacatctca ccggggcggt ggtgattccg
     3541 gggatggcgg acattatgga gggaatgcgg gcagttgcag ggattgggat tgttctgatt
     3601 ggaacctttc cggcgctcac cattctcaca aagctgctgg acaaaccgtt aaaccgggcg
     3661 gggaggaagc tgggacttga taagaccagc gcggcaggcc tggtatttac gctggctaat
     3721 tctgttcctg tttatacgat gatgaagaat atgaacaaaa agggcattat tgtgaacaca
     3781 gcctggctgg ttccggctac gtcggcgctg ggggctcatc tgggatttac ggcaggggta
     3841 gaaccttcca tgatcactcc tgtcgtggcg ggaaagctgt cagccggcgt acttgccgtg
     3901 tgcctggctc tctttatgtg cagggacatg gaggaggcgt gagaaggaag cgaaggaaga
     3961 gattggggag gtggaggaca tgacccacaa ggatcagacg ccgctggcgc agattgcggc
     4021 agaaaaaatc atagagatga tccgggaaga gaaactgcag ccgggagacc gtctgcagaa
     4081 tgagtatgat ttggccaaga ggctggaagt gggaagaagc acagtcaggg aggccatcaa
     4141 aagtctggaa accaggaaca ttttaacgat cagaagagga gccggaactt acctgtccag
     4201 ccgggagggg gtggcggagg atcctcttgg gattgcgctg atgggaaaag acgaggagat
     4261 tgccctggag cttttggagg ttcgcatgat tctggaaccg gaaagcgcgg cgatggcggc
     4321 ggtccatgct tctaaggagg agaaggctgc catacgcagg cagaatcgga gagttactgc
     4381 gatgattgag caggggctca accacacgga agaagattcc aagtttcatc agctgattgc
     4441 aaaggcgacg ggaaacagga ttatcgccaa gctgattccg attatttacc gatcggtcag
     4501 ccttaccatt gagatgacaa accgccggct gtcggagaca accatcctgt tccacgaaca
     4561 gattgtggac gccattgagc gcggggacga gaggggagcg agaagcgcga tggtggcgca
     4621 catgagtgaa aacaggcttt acatcattaa ggagatcgag agaaagaacc gtttccagta
     4681 aacgaaaaag agcaaagaga gacaatttag agatcagacg tatctgaaaa gaaaaaaacg
     4741 agcagaaaca gcgtaaaaca ggcaggttga acgcttttct gactcgtttc ttttttgacg
     4801 atttttaaga catcagacaa atttagggcg gttatttgta tataatacat ataaaataca
     4861 cttaaaatcg tgtaaaaaag agaaaaatat atacaatatt gctaaaaata agtgtgtaat
     4921 atataataaa acacataaaa taaatcagac atattgcgcg aggaggagag caaatgaaag
     4981 cgttagtgta tgcgggacct aaaaaagcgg agcttcggga cgtagagaca ggggaaaaga
     5041 aggaaggcca gataaagatt gacgtaacct actgcggcgt gtgcggatcg gatattggaa
     5101 tttatctggg aacccatcca agggcaaagg cgcctcttgt gtttggacat gagtttctcg
     5161 gagtggctgc ggaagacgga aagagaatca aaaaaggaga cagggttgtg ccttatccgt
     5221 tattgtcctg cggacactgc aaagcgtgca gaaacggaaa tgagcatgtg tgcaatacgc
     5281 tggggctgat cggaattgac gtggacgggg gaatgtgcga aagcgtttat gtggacgagg
     5341 acgttctcta caaggtgccg gagggagtca gcgacaaggc ggctgcagtg attgagcctt
     5401 tggcagtgct ggttcatgcc atccatatgt cagggtttga gcctcttgat acggcggtgg
     5461 tggcaggcgc cggccctatt ggaatgctct gcgcagttat gctgaaacat gcgggagcct
     5521 cacagatttt tatttccgac gtggcggaaa agagactgga ggctgccagg gagctgggca
     5581 tgattccggt caatccgctg aaagaggatt tggaagctgt ggtaaaagcg gcgacggacg
     5641 gagagggatg cgacgtattt ttcgagtgca gcggagctgc ggctgcggct gtgcagatga
     5701 cggatgtcac gagagtgcgg ggaaaaatct gcatggtttc agtccacaag cagccccatg
     5761 aagtgaatct gcgggatgtg aattttaagg aacagacact ggtgggaacc agagtttaca
     5821 cgaaggatga gtttggccag gccgtggagc tgacgaagaa gctggaaagc cagctggaga
     5881 agattgtgac ccatgtagtg cctcttcggg aaagcgaaaa ggtctttgac atgattgcgg
     5941 atccggaatg cggaaccatt aaggttgtgg tggattgtaa ggcggtatag atgggcagaa
     6001 aaaggaggag agggaatgaa acagagaggg aaggcagtca cggcaggatg tattctgctg
     6061 gctctgctgg cgggagtcgg gtttacgaag gctggaagca agtacaggac gcaggaggaa
     6121 gtgaatctga ttttttcaaa cgtaacgtcc aattcagcca aacaggcggc agaaaagttt
     6181 aaggagctgg tggaggaata ttctggagga aagatgacgg tggacgtgtt ccaggacaac
     6241 cagctgggag acgacaagac ggcggcggaa ggcgtgcaga atggagacat tgatatcgca
     6301 gtatcgtcta ccagttcctt atctacgctg tataaagact attatctcta tgatactccc
     6361 tacctgttct taaataaaga agaggtgtac gacgtgggct ttacgggaga gacggcgaca
     6421 aagatgctgg aaggcgtgga aaaggtcggc ctgaagcata tggcgatgtg ggaaaacgga
     6481 ttccgaaact atacgaacaa cgctcacccc attgaaagtc cggcggactg taaaggacag
     6541 aagatccgta ccatggaaaa tccgattcac atgaaggcgt ggaaggagat tggagccaac
     6601 cctacgccta tggcgttttc cgagctgttt acagccatgc agcagggaac ggtagacgga
     6661 gaggaaaacc ccatcggaat tatttccagc aaccggtttt acgaggttca gaaatatatt
     6721 tctttgactc agcatgtcta tacgccgtat gtggttgtta tgaatcctga caaatacgac
     6781 acgctgacaa aggagcagca ggaaattgta gaccgggcca tgaaggaggc gacgcagttc
     6841 cagcttgagc agtcggcgaa agacgaggaa gagggaatta aaatcatgga agactacggc
     6901 tgtgaggtca acgagctgac agacgagcag aagatggaat tccagaaaat tatggaggat
     6961 gcggacgtat ttggagtggc aaaagacgcg atggagaatc cggagtattt tgacggaatt
     7021 ttgaaggagc tggaagaata ccgggcggaa ggagaacagt aaaaaatgaa gaaaggactg
     7081 cagtttttaa atcgttatct ggaagagatt ctgtgcgtgg cgctgatgtc agttatgacg
     7141 attatcatat ttgttcaggt tatcatgcgg tatgtggcgc acaattccct gtcatggtca
     7201 gaggagctgg ccagatactg ctttatctgg ctgatttaca taggagtagc ttacggatgt
     7261 aagctgatga agcatattaa gattgacgcg gcgctgtatc tgtttcccaa gaagctcaga
     7321 ccgtacataa ccattctggg ggagcttctg gtgttaatgt ttgcggctta cattgttgtg
     7381 acaggagtgg agcttacata taagcagtgg gtattcggaa aggtgtctcc ggcgctggga
     7441 ctgcctcttc agtatatcaa cgcggctccg gtcgtaggat ttggacttgt gattataagg
     7501 cagattcaga acatctggta cctggcaggt aatcttggaa agacagaaga agggggcgaa
     7561 gaatagtggt agcgattgta ttatttggaa cattagtaat tgccttaatt ttaaatatgc
     7621 cagtgggaat cgccattgga ctgtcctcgc tctgcgcagt cctggcagat ggaagactga
     7681 gctctctgta catcgttcag cagctggtaa ccagtgcaga ttccttccca ctgatggcaa
     7741 ttcccctgtt tatcctggcg ggagagctga tgggagcagg aggtgtatca aaacgtcttc
     7801 tcaacgtgtg caacgtattt ctgggaaggt ttaccggcgg tcttgccacg gtgacagtag
     7861 tgctctgtat gttctttgcg gctgtatcag gatccggccc cgccacagtt gcggcaatcg
     7921 gttctatggt cattccgact atgctgcaga agggatacag caaaagcttt accctggcgc
     7981 tgatcgcgac tgcgggaagc attggagtta ttattcctcc cagtattccc atggtggtgt
     8041 atggagtctc caccagcacc tcgatcagct ccctcttcat ggcaggcttt ctgccgggac
     8101 ttttgattgg atcgtccctg attctgatgt cttacattta ctgcagacgc cacggatgga
     8161 agggggacga caggagatac acattcagag agaagatgga agcgatctgg gatgccaaat
     8221 gggctttgat caatccgatt attattctgg gcggcattta tgctggagtg ttcacaccga
     8281 cagaggcggc agccgttgcg gcagtgtatg cgtttatctg cggcgtattt atttataggg
     8341 agcttgattt taagcagctg ttcgggaccc tgggaagcgc gtgcagcaca acgggaacta
     8401 ccatggtaat cattggctgt gcgactgctt ttacgagaat cctgaccatt gaaaagattc
     8461 cggatactat tacgactgga attttaaact tcagcgacaa catgattgtg attcttcttc
     8521 tgattaacct gcttctgctt gtggttggat gctttatgga caccaccccg gccatgatgg
     8581 tgctttcgcc gattctgctt ccaattgcga tgcagtttgg cgtggatccg attcatttcg
     8641 gactgattat ggtcgtaaac ctggccattg gatttatcac tccgcctctt ggaatcaacc
     8701 tgtttgtggc ggccagagtg ggaggcagca gcctggaaac cgtatgctct ggaatcatca
     8761 agtttattct ggttatgatt cttgatctgc tcctgattac ctttattcca ggcatctcca
     8821 tgattctgcc aaatacgttt atgtagggcg gcgaaagaaa gagaggagaa aacatgaatt
     8881 tatttgattt aacgggaaag acagcgattg ttacgggcgg aaccagggga cttggccatg
     8941 gaatggctga aggccttctg gaagcaggat gcagagtggc ggtaatagga accggagaca
     9001 gcgtatttga acgagcagag gaatttcggg agagaggcta tttctgcgag ggcgtgaagg
     9061 ctgatctggg atgttcagaa gagagaaaac gggcgtttga cgagtgcgtt caaaagctgg
     9121 gaggccgtct tgacattctg gtgacggccc acggcatcca gagaaggcat ccttcggagg
     9181 aatttcccat ggaggactgg gaacaggtgc tgggggtaaa tctgacggca gtctttgagc
     9241 tgtgccagct ggcggccaat cagtttctct cccagaagag caagggcaag attataacgg
     9301 tatcctccat gctgtcattc ttcggaggct acacggttcc agcttatgca gcgtcgaaag
     9361 gaggcgtcgc ccagctgacg aaggcccttg gaaacgagtg ggcagggaag ggaatctgtg
     9421 tgaattccct tgcgcccgga tatatggcga cggatatgaa tacggcgctt atggatcctg
     9481 acaatccgag aaaaaaagag attacggaca ggattccgga aggccgctgg gggacaggcg
     9541 aagatatgaa agggccgtgt attttcctgg cgtctgacgc gtcggattat ttaagcggcg
     9601 cggtgattcc ggtggacggt ggatatctgg tgcggtaaac cgcaggaaaa gaaggaggaa
     9661 gagaagatga aggtaattat tacagactgt gatcatgaca atattgagat tgagaaaaag
     9721 atctttgcgg atgcgggaat tgagatggag ctgaagcacg ccatctctga ggatgaggtg
     9781 attgaacagt gccaggatgc ggaaatcctg attgtccagt atgccaagat taccagaaag
     9841 gtaatggaac attgtccaag gctgaaattt gtggtgcggt acggtgtggg cgtcgacact
     9901 atcgatgtgg cggcggctgc agagtttgga gtacagattg gaaacgtacc ggactacggc
     9961 atgaacgagg tggcggatca cgcgattgcc ctggccctct ccatgacaag agagatagtg
    10021 aaaatgaatc agtttacaaa gaacgagaaa tgggactaca caaaggcaat tccgattcac
    10081 cgtttcagca atctgacagt cggcgtcatc ggcctgggca gaatcggaag aaatttcgct
    10141 cagaagatgc acgcgctggg atttcaggtt attggaacgg atccgtattt ttctcctaca
    10201 gaggaaacca acgcctatgt gaaggcggtt tccatggacg aggtaattga gacgtcggat
    10261 attatttccc tgcactgtcc ggcagacgga aaccgggatc tcttctgtaa ggaaactttt
    10321 aagcgcatga aaaacacagc ggttctgatc aatgtggcca ggggcggcat tatcaatgaa
    10381 acggacctgg atcaggccct gacagatggg gaaattgccg gagccgccct tgactgcatg
    10441 gcgggagagc cggtatccaa ggattcgccg ctgtttgccc atgaaaatct cctggttact
    10501 cctcatatgg cctggtactc tgaggaggcg gcccaggagc tgaagcggaa ggtggcggag
    10561 gaatccgttc gttttgccag aggagagaag attcattatc cgattaataa gctggcataa
    10621 gggggagaat gcgatgcatg aagtattaaa aaaagtagag cagttcggcg tagtgccggt
    10681 gattaagatt gaggatgcaa acgatgcggt tccccttgcg aaggccctgt gcgaaggagg
    10741 tctgccctgc gcggaggtaa ccttccggac agaagctgcg gaagctgcga tccaggcgat
    10801 gagggaagct tatccggaca tgcttctgat tgccggaacc gttttgacta aagagcaggc
    10861 agaccgggca gtgtcagccg gagcgcaggc agtggtcagc ccgggcttta accgaaaggt
    10921 agtagattac tgcgtgcgga aaggaattct cattctgcct ggatgctcct gcccaagcga
    10981 tatggagcag gccattgagg cggggctgtc tgcggtgaaa tttttcccgg cagaggcaag
    11041 cgggggaatc aaggcgatcc aggcgatggc ggcgccttac gggcagcttc ggtttatgcc
    11101 tacaggaggc gtaaacgctg taaatatgca ggagtattta aaaaacgaca aagtcctggc
    11161 ctgcggcggt tcctggatgg tgccggaaaa gctgattcag gaaggcagat ttgaggaaat
    11221 cagacagctg acaaaagaag cggttctggc ggttcatgga tttgccctgg cccatgtggg
    11281 aattaacagc gcagacgagg aggaggccag aaagacggcg cagacttttg agcgcctgtt
    11341 tggatttgag tcccatgaaa atccgtcctc tatcttttca gcctcctatg tggagactat
    11401 taagaagcct tatctgggag cgaaagggca tatcgccatt gcagttcatt cagtggagcg
    11461 ggcgaaggcg tatcttgaga gaatgggaac ggaatttctt gaggacagcg ccgtgtaccg
    11521 gccggacggc agaatccagg cggtatatct caaagaagag attggcggat ttgccgtcca
    11581 tctggtgaga agagcagtct gacagacggc agagcaagga gggagagaag atgggaaaga
    11641 ccattttgtt tggagagccg atggctcttc tgattgctga taccacaggg ccgctggagg
    11701 aagtggagca tttcaccaga gcgctttccg gcgcggaggt aaatgtttcc atcggccttt
    11761 ccagactggg gcatccggtg gaatacctga ccaggctggg agacgatccc tttggccatt
    11821 atatagaaaa ccagctgaaa aagaacgaga ttggaaccag tatggtgacg tatgatccgg
    11881 tataccgcac gggaattcag ctgaaaaacc gtgtgacaga cggaagcgat ccctatgcgc
    11941 cgtactacag aaagggttct gcagcctccc acatctcaaa ggcggagata gacgcgcttg
    12001 acttgactga tgtggagctg atacatgtga cgggcattcc ccccgcgctg tcagaaagcg
    12061 caagggaggc gtccttctgc ctgatgaaac gggccagaga ggcggggatt tttctcacct
    12121 ttgatccaaa tctcagaccg gcgctgtggg aaaatgaaga gaccatgatc cgggtcatca
    12181 accagcttgc gtccatggcg gatgcggtgc ttcctggaat cggcgagtgc agaattctgg
    12241 cgggaaccga tcagccggaa gaggcggcag atttctacca gaatctgggc gtgaagacgg
    12301 taattgtgaa gaatggggcg gacggagctt acgtcagaga aggagaagcc tcttactgcg
    12361 tgcctggata ccgggtggag aagatcgtag atactgtagg cgcgggagat ggatttgcag
    12421 tgggagtgct cagcggaatg ctggagagac tgtccatgag agacagtgtg cttcggggaa
    12481 atgccatcgg tgccatccag gtcatgaata tcagcgacaa tgaaggactt cccacacagg
    12541 aggagcttcg gaagttccag actggcacaa aagctcagat tttgtgacct gtcatttccc
    12601 ttgttggcaa atgctccccc aggtattata atgaaatcat agataaatgc cagacagggg
    12661 gagaaaacca tgcttcagag caggagggaa aaaatagcag agatgatcca ggcggatcgg
    12721 gtgctgaagg tcagcgatct gatgagacag ttcgacgttt ccatcgagac tatccgcaga
    12781 gatttagaat atctggaaaa acaggggctt ttgacacggg tatacggagg tgcggttctg
    12841 aatcagaaga aggggaagga acccctctat gagcagcggg agattaagca ttatgcggaa
    12901 aaggcggcca tcgcccaaag agcggtggag cttatcgagg acggcgacgt gctgggaatc
    12961 gacattggaa cgacagccag agagtttgcc aaagctctga ttggaaagaa aaaagtgatt
    13021 gtgctgacca attccatgcc gattgcagaa attttaagcg aggatgaaaa catccgcgtc
    13081 ataatgctgg gcggagaggt caggaaggga gaattttccg tttccggctt tgtggcagag
    13141 caggtgatga gccggttcaa cctggataaa tacattctgg ggatcggagg tttgactgtg
    13201 gaaaacggca ttacagacta tcacattgag gagacgaatc tgagacgcgt catgctggag
    13261 cggagccaga aggtgatcgg gctgacagac tacagcaaat tcggcgtgat tgccatgaac
    13321 gaggtgtgcc ccctgtccag gctggacgtg ctgatcaccg acagccgggc ggatcggatg
    13381 atcataggaa aaatgcacac aatgaagaca gaggtcatcc agattgaagc gccaggagaa
    13441 cagccggata cggaacagta agagatgtga ttccttccag ggatttctgt caaggcggcg
    13501 gacttctgtc acggcagcag aagggaaaag ccgtaataaa aataaaaaga atagaataaa
    13561 atgagaaaga gaagagcgtt aacaggctgt gtgccaagtg aaacgcgctt ctctttttta
    13621 tttcttcaga aagtgcgtct gatgaaataa aatgtggaat taattgtatt tacgaaaata
    13681 atcacaacat acagaaaaaa tatgcacaaa aacatggctt taaaatcagt tattttgtgg
    13741 tattgatttt aaaaatggaa agtaatacaa taaaatacaa caaaacatgg agaaatgtgt
    13801 ggatttttac aacaaagcgc tgggcagagc gcaggaaaag gaggaaactg catgacattt
    13861 gaccaaatca ttctttgggt gatggcggcc ggagttctga ttggagcggc tgacaagatt
    13921 tttgggaacc ggctgggact gggggagaag tttgacgagg gattccaggc tatggggccg
    13981 ctggctctgg gaatggtggg aatcgtctgt ctggctccgg tgatcgcaga tttgctgggc
    14041 cctgtgatta ttccggtatt tgaggcgctg ggagcggatc cggccatgtt cggagcgatt
    14101 ttagccaacg atatgggcgg ctatcctctg gctgtggagc tggcccagga tcaggaggcg
    14161 ggacttctgg cggggaatat tgtggcgtcc atgctggggt gcacgctggt gttttcgatt
    14221 cccgtcggac tgggactcat tgaaaaggag gaccgtcctt acttttccaa agggctttta
    14281 atcggcctca ttacgattcc ggcaggaagc gtcataggag gcctgattgc aggctttgat
    14341 ccgtccatgg tgctgtggaa cacagttccg gttatcatcc tggcagcagt tctggctctg
    14401 gggcttaaat tcattcccga ggccatggtg aagggatgca tggtattcgg acagtttatc
    14461 acgattgtca tttacatagg actggcggct gctgcctttg agcatctcac cggagtggtg
    14521 gtgattccgg gaatggcaga tattatggaa ggcatgagcg ccattgcggg aatcggcatt
    14581 gtactgcttg gaaccttccc ggtgctcacc attctcacca aggtgctcga caagcctctg
    14641 aaccgggcgg gacagaagct ggggcttgat aagaccagcg cggcaggtct tgtatttaca
    14701 ctggccaact ccgttcctgt ttataccatg atgaaggaca tgaataaaaa gggaattatc
    14761 gtgaatacag cctggctggt tccggctacg gcggctctgg gagatcacct gggatttacg
    14821 gctggggtag agccgtccat gattacgccg gttgtagtgg gaaagctggc ggcaggcgtg
    14881 attgccgtgt gtctggcgct ctttatgtgc aggggcatgg agcaggagca taacaggcag
    14941 cagccggagt aactggcggg agaacattcg gggtgtttga aagtgtttat cagaatcgtc
    15001 agaatagata gaaagcagta aaggaggaaa acagttggag aagtattatt taggtttgga
    15061 tcaggggaca acaggtacga cagcgcttat ttttgattcc cagtggaatc agattgccag
    15121 aggatataag gagcataccc agtattatcc gaaaccggga tgggtagagc acgatcccat
    15181 ggaaatctgg aacagcattt tggagaccat agccatggcg gccgaggagg cggggatcca
    15241 ggtggcggat ctgacctgta tggggcttga caaccagggg gagacggtga tgctctggga
    15301 ccgctacaca ggcgttccgg tgtacaatgc cattgtctgg caggacagac gaaccgcgaa
    15361 gatggcagac gagctggcgg agaaatacgg agatctcatc cgggagcgga cgggactggt
    15421 ggcggacgcc tatttcagcg ccacgaagat acgctggatt atggatcatg tggagagagt
    15481 cagggagaag atagagaacg gccatgtgat tgcaggcacg cttgatacct ggatgatctg
    15541 gaagttgact cacggccatg tgcatgtgac ggattactct accgcttcca gaactatgct
    15601 gttaaatatt catacaggag agtgggacga tgacatttta aaggctctgg gcattccaaa
    15661 gaagattctg ccggaaatcc acgacagcgc agaggtctat ggatatacgg atccgctgga
    15721 tttcttcgga gccctgattc cgatttccgg ctctgtggta gatcagcagg ccgctctgtt
    15781 cggccaggcc tgcttcaaac caggaacagt gaagactacc tatggaacag gctgttttat
    15841 gctgatgaac acgggagata agccggttta ttcggaaaac ggccttctga ccaccgttgg
    15901 ctggggattg aaccagaagc agatgacttt tgccctggac ggcggcattt acatatcagg
    15961 agcggcagtc cagtggcttc gcgacaagct tcacctgatt gccagcgcgg ctgagacgga
    16021 ggatctggcc aaatctgtgc cggatacagg aggcgtatac tttgtgcctg cctttgccgg
    16081 actggcggcg cctcactggg atcagtacgc cagaggaacc attgtgggaa tcacaggagg
    16141 aaccacaaag gagcagctgg tgcgggccac gttagagagc atcgcttatc aggtgaagga
    16201 caatctggac gtgatggtaa aggattcggg aattcccatt gaggtgatgc gcgtggacgg
    16261 cggagcggtt gtcaatgaat ttttaatgca gttccaggca gatattctgg gaatcccggt
    16321 ggacgttccg gtgattaccg atacgacggg tctgggagcc gcctacctgg ctgcctacgg
    16381 aatcggagag ttccacgatc tgtcagagct tgagcacaac tggaagcttt ataaaagata
    16441 tgagccgcac atggaggaat cagtcagagc agagcttctc agaaactggc acagagcggt
    16501 agagcgggcc aagagctggg cagagaaata agagtgagac aggaggaacg agggttatga
    16561 ggacaaacgt agtagtaatc ggagccggcg cagtgggctg cgctgtggcc agagagcttt
    16621 ccaaatataa aatcgatgtg gttgtggtag ataagaatga agacattgga ggggacgcct
    16681 caaaatccaa cagcgccatt atccacacag gctatgacgc ttctccggga acgctggaat
    16741 cccagctggt cgtggcggcc aatcccatgt acgacgagct ggcgagagat ctggacgtgc
    16801 cgtttaagcg gatcggagcg attctgccgg ccattaccca ggaacagtat gagaagctgc
    16861 cggagattaa ggccaaagcc ttcaaaaaca gggtgtatga cgtagagtat aagacaggcg
    16921 aggagcttct ggctatggag ccgaatctga atcctgaggt aaagggaggc ctttacattc
    16981 caagagagag cattatcgac ccgtttattc tggtgcaggc gctggcggag aatgccaatg
    17041 aaaacggcgt ttccttcctg ctcaatacaa aggtgacggg gattcagaca gagaatggaa
    17101 aagtgaaggc cgtggagact acaggaggaa tcatagagac cgactatgtg atcaatgcgg
    17161 cggctctcta ctgcgacgag atcgcggcta tggtgggcaa ggcagattac aaggtggtgg
    17221 ccagacgagg acagttctat attttagata agaataccag ctgccaggta gagcacatcg
    17281 tgcttccgat tccaaccaag gtgacaaagg gcaagctgat gtgtcctacc attcacggaa
    17341 acatgctggt aggcccgact gcggaggatc tggacaataa gacggataag agcgtgacgc
    17401 cggagggcct tcagagcatt gtggacgatg tgaaacggct gattccaaac gtcaatgtaa
    17461 gagataccat tacccagtac agcggcctgc ggcccaaccg gaatcctgag ggactccatg
    17521 tggatatgtg ggaggatctg gagggctttg tgaatctttc cggcgtccgt tccacaggcc
    17581 tgacactctc tgtggccatg ggaaaatatg tggcgcagct gcttatagat catggcgcgc
    17641 cccttgtatt taaagaaaat tttaaaaaga ccagaaaggg aattgtccgg ttccatgagc
    17701 ttagcaggga ggaaaaggag aagctgatta aagaaaatcc ggcctacgga accgttatct
    17761 gccgctgcga gaccatcaca gagggggaga ttttagactg tatccgccgc ccgctgggag
    17821 ccagaagcat ggatgccgtg aagcggagag tgcgcgctgg aatgggacgg tgccagggcg
    17881 gtttctgtgg tcccaaagtg attgagattc tggctaagga gtggaacatt ccggtggaac
    17941 aggtgaacaa gaataacgca ggttcctaca tggtaacagg aagaatgaga tagcaggaac
    18001 ggtatcggtc agagacagca gacagaagga gaggtttgta tgtatgagat aacatgtgat
    18061 gtggcgatta taggggcagg cccggcagga ctttccgcag cggtggctgc aaagaaagag
    18121 ggagcagaaa gggtgcttct tattgagcgg gacgagagtg tgggaggcat tttgcagcag
    18181 tgcatccacc cgggctttgg actgacctat tttaaggaag agctgacggg gccggagtat
    18241 gccggacggt ttgaggacga ggcagagaag ctgggcgcgg aggttctgct gaactctatg
    18301 gtgctggagg ttgtgccgga ggaaaatgta gtgtactgcg tcaattccag gtatggaatg
    18361 acgagagtga gggcaggaag cattgtcctg gccatgggat gcagggagaa gacgagagca
    18421 ggaatccaga ttcccggaac cagaccggca ggcgtctaca cggcgggagc cgcacagcgc
    18481 ctgattaacc gtcagaacgc catggtaggc agggaagtgg tgattttagg ttccggagac
    18541 attggaatga tcatggccag gagaatgagc ctcgagggag cccatgtgaa ggcagtagtg
    18601 gagattatgg attttctggc aggccttacc agaaataagg tacagtgcct ggacgacttt
    18661 gacattccgt taaagctgtc ccacacagtc accagaatcg tgggaaacga gagagtagaa
    18721 ggcgtgtatg tggctgcagt agatgagaat aaaaagccca tccttgagac agaggaattt
    18781 atctcctgcg acacgctgct tttgtccgtc ggacttctgc cagaaaacga gctgacgagg
    18841 caggcgggaa ttgagatgaa tccggtgaca aacgggccgt ctgtgaatca gtatatgcag
    18901 acctcggctc caggcgtttt cgcctgcgga aacgtggtgc acgtcaatga tctggtggac
    18961 aatgtaacga cagagagtat gcaggcaggg gcctgcgctg ccaggtacgc cgcactctgg
    19021 aaagacgggg cggttcaggg agaaatggca ggagagcgga attctgtgaa agctgtaccg
    19081 ggatcaaacg tgcggtatct ctgcccacag tccatctgcc tggacagttc tttaaagaga
    19141 aactctgaaa atgagaccgt ccgcctgttt ttcagagtgc tggcgcctga tacagaagta
    19201 aagattactg ccaagtgcgg cgaaaaggaa attaaggaaa aaaaggcgct gcgggttaat
    19261 ccgggagaaa tggagtctat tgaaatcccc ttacatcttg tgacaggcga tgtgacggtt
    19321 gaaattgaga aggaggcgta aacctatgac aaaggaaatc atctgtacag tctgccccat
    19381 gggctgtcat attctggtgg agggagaggg agatcaggta acctccatca caggatatac
    19441 ctgccgccgc ggcgaggaat acggacgcca ggagttttcc catccggtgc ggattctcac
    19501 caccacagtg aagacagaca gcgaggccca tccccttctc cctgtccgct ccagccgtcc
    19561 agttcccaaa gagcttctgg cacagtgcat ggaggagatt agaaagaaga aagtaaccgc
    19621 ccctgtgaga aggtatgatg ttataataga gaatatatgc ggatgcggag cggatattgt
    19681 ggcgtcaggg gagataaggt aagggaccat acgaaacaag caggcataaa gactgtcatc
    19741 aaacagtctg tgcctgcttt ttctgcgcct gtttatcata atcattttcc tgcgtgcttc
    19801 ctgatattac tttacccgtt ttccctcgtc cagccagctt tccagctcac ggtggctgag
    19861 cgccagaacc atctggatat cctgctgttt tttcaaaata agagccaggc cggcgatgac
    19921 gccgcacagg acggcaatta taactgtttt catatctttc atcgtatacg cacctccatt
    19981 ctagttcatt ataatcaata taaggataat attcaactgc tagagagcga aaaaagagaa
    20041 atccacagaa agaatgagct tctgtctgtg gattccccat ataagagagt atttacttag
    20101 ctgcctttac agattctgcg atggcgtctg ccagcatatc cagctctgcg gccttatcag
    20161 gcagaaggga ggaagctaaa gataaacgct cgttcagaac cgtcatattt tttaactcct
    20221 cgttgatgaa tttctgcatc aaatcgccgg acttgcaggc ccaggaacca ttttcgatga
    20281 gggcgaaggt acggttctgg agattcagcg ccttcatatc catcaggtaa ttgtgcatca
    20341 ccgggtagat gcccagattg taggtgacgg acgccagcac aatgtggctt aaacggaagg
    20401 actcggaaat cagctgggaa atgtgagtgt tcgacacatc gtacatccac acatttgtac
    20461 agcctctctc gcagaggcgg gatgccaggg cctgagcggc agcctctgtg ttgccgtaca
    20521 tggaagcgta tgcaatcata acgcccttct cctccggctc atagcggctc cacttatcgt
    20581 atttatcgat aaaatagcct aaatcctttc tccacacagg tccatggaga ggacagatat
    20641 agtggatctg gtctaaaatt ccagcggctt tctttaacag aagctggata tgaggaccgt
    20701 attttcccac aatatttgac agatagcggc gggcgtcgtc aatccagtcg cggtcgaaat
    20761 tgacctcgtc ggcaaagagc tttccgtcta aagctccgaa ggagccgaag gcgtcggcag
    20821 agaagagaac gccgtctgtc gagtcaaagg aaaccatgac ctcaggccag tgaaccatgg
    20881 gcgctgcaat aaactgaacg gtgtgctttc caaaggagat ggaatctccc tcttttacct
    20941 ccatgagagg gtgggagtct acggcaaatc cgaactggcg catcagcata aaggatttct
    21001 cggtgctgat aatagtcaca tccgggtagc ggagcagcac ctcttcgatg gaagcgccgt
    21061 gatccggctc catgtggttg ataaccagat aatccagagg acgtccgttt aacaggtgat
    21121 ccagattttc cagaagctgg cggcatgccg cccagtccac cgtgtcaaac agggcggtct
    21181 tcttgtctaa gagaaggtat gcgttgtagg aaacgcctct tggaatcggg tggatatttt
    21241 caaacagatg aaggcggtgc tcgttggctc ctacccagta aatatcatct gtaaccttgc
    21301 gtacacagta cataatctta cctcctttgc cttatgcctc aataaacatt tcttttgatt
    21361 ctgcacattc cgggcagacc cagtcttccg gcagcttttc aaacagagtg cctggagcga
    21421 tatcgccgtc ctcgtcgccc agctccggaa tgtactcgta tccgcagccg ccgcagacat
    21481 agcgctttcc gattggttcc ggcttcggag gcagaggcct cttgattttt accataggag
    21541 gagccggctt cttttcctcc agacccagct cttcggccag cagaggcaga atttccttca
    21601 catctcccac gattccatag tcgcagtttt taaagatggg agcgtttccg ttggtgttaa
    21661 tggctacgat ggtagaagcg tccttgatgc cctttaagtg ctggaccgct cctgaaatac
    21721 cgcaggcaat gtagagattt ccggtgaatt tctggccgga catgcccaca tagcggttca
    21781 gcggaacgta ttttaacgtt tcggctaccg gacgggagga accgacagcg gctccggctg
    21841 ccttagccag ctgctcgatc agcttcatat tttctttctc cccgataccc tggcctgcgc
    21901 tgactacgcg ctctgcctgg atgatcggag tatccatcgg aatgccgaca gtgaagtcgt
    21961 atccgtcctt tctaaggaga gcggccagct ctgtagcctg ttccttcgga cttccctctg
    22021 tgatcatgtg gcgctttctg acacctgtca caggagccgg ctttttcgga cggctggagg
    22081 aacctgacgc atccttcggc ggtttaccca gaagagcgga agaaataacg actctctgaa
    22141 tctcattggt tccttcatag atagtggtaa ttttagcgtc acggtacata cgctcaacgt
    22201 ccataccctt taagaagccg gttccgccga aaatctgaac ggcgtcgttg gtcacctcga
    22261 gggcaatgtc ggaggcgtac atcttagcca tggcagattc catgccgtaa ggctcgtggt
    22321 gctccttcaa ctctgcgctg gagtagacaa ggaatctggc gcagcgcagc ttggtagcca
    22381 tgtcggccag cttaaagccg attgcctggt taaagccgat gggctttccg aactgaacgc
    22441 gctcctttgc gtagtcgagg gcgctttcgt aggctccctg agcgattccg agggcctggg
    22501 aggcgatacc aatacggccg ccgtccagag tggccatggc aatcttaaag ccctgtcctt
    22561 cctttccgag gaggttctcc ttgggaacct ttacattgtt gaaaatcagc tcggcagtag
    22621 aggaagaacg gattcccatc ttgtcgtagt ggtcgccgaa agtgaagccc ttccagcctt
    22681 tctctacgat gaaagcagag atgccgcgcg ttccgatatc aggagtcgtc acggcgaata
    22741 ccacataggt gtcagcctta ggagcgtttg tgatgaagat cttaccgccg tttaacagat
    22801 agtggtcgcc cttatcgatg gcggttgtct cggtgccgcc ggcgtcagag cctgcgttag
    22861 gctcagtcag tccaaaggcg ccgattttct cgcccctgca gaggggaacc agatattttt
    22921 tcttctgctc ttccgtaccg aaggcaaaaa taggccagga gcccagggaa acatgggcgg
    22981 agagaataac gcctgtgcct ccgtctacgc gggaaagctc ttctacggca atggcgtagc
    23041 tgatcacgtc cagtccggcg ccgccgtact ccttcggata cgggattccc atgagaccca
    23101 tctcgcctaa ttttttgacc gcctcgtctg gaaaacggtt ttccttatcc ataagaaatg
    23161 cgtggggctt tacctcttct tcagcgaagg cgcggatttt ggcacgaaga gcttcgtgtt
    23221 cagcagtagt atgaaacagc ataggtagat cctcctttcg aatcgtaaaa tcataataaa
    23281 aaattaataa caataacaat aatcattttt atattataga tattaccata ctctgccagc
    23341 ttgtgtcaac taaaaattat gcaaaaaaca gataaaaaag aattacaaaa gagtgggatt
    23401 gtacaaaaaa acgaaaaaag cagcgctgac gcacaaagga aatactgcac tttgtacatc
    23461 agcgctgctg aatagataga aaggattaac gctcagacgg gaaaacaggc agaagtgtct
    23521 ggctgatgcc gtcgacaaga ccgaaatcgg tgatcgtcac gccgggaagg gcggttaagg
    23581 acataatcga agcgcccagc agagacgttt ccggggtggt gatttcctga acggccttct
    23641 gaaccgtttc aatccgctct gccatctggc ggcagggcag attggacatt aagccggcca
    23701 cgggaagttc cagaacagac gctttgctgt ccttgactgc acagatgcct ccgccgcagg
    23761 cctgcagagc ctgaacggct tttaaagcgc tttccggatc acggtagacc acaagcaggt
    23821 tgtggctgtc gtgggtgatg gtggtggcga aagcgccctc gcaaagaccg aagttttcaa
    23881 acacgccgat gacctgtttt ccgtttccgt accggttgac tacgcttaca aactggagat
    23941 cctcacggcc ttccaaagat acggctccgt ctctgacagg aaggctgacc ggacggacgg
    24001 tgcggagaat cttgtcagcg gaaggcacca ttacatttac ctcaatcgtg tcctttgcat
    24061 agttctcagg aacggtgaga atgaaatctg ccgcagagga gatctgggga atattgactg
    24121 tatttttaaa ggaagaagcg gccggctcag gatcgcatcc tgtatacacg ccgttttcgg
    24181 ccaccttcct tccctccata aagacagcct ctggctggct tccgtccagg cggcgtacca
    24241 gctggaaatc agcaacatag ccgggagcca ctgctcccag atcctgaatg cccagctcct
    24301 ttgcagcgtt taaggtggcg catttaatgg cgtctaaaga gctcatgccg gctgcgacag
    24361 cccgttttac cacccggttc acatggccgt cagccagcag gtcgctggca tggacatcgt
    24421 ctgtacagaa ggaaacgtga tcgtaccatc tgtgtccgtc cagaccgcgg atcaaatccg
    24481 gaactacatc gcataaagag cttccccgaa cgtttacatg catgcccagg cggagcttct
    24541 cccgcacttc cgccgcgctc tggctttcgt gatcgctttc cggacctccc aggcggtagg
    24601 cgcacagctc cctgcctgtg acagtggggg cgtggccctg aaggaaggcg ttctttttaa
    24661 ggccttcgtc aataattgcg tgcatcctgg ggctgtcctt gtaaacgccc acgaaatcca
    24721 tgatctcagc aatgccgatg acgccttcct tttccagaag cgtgcggatt tcaggggctt
    24781 caaaggaagc gccgctgctt tccaggcctg ggaccgccgg cacgcaggag ggagccagca
    24841 catactggcg cagagcagac ttcttcgcgt tttccagcat aaattctacg ccctcgatgc
    24901 ccatgacatt tccgatttcg tggggatcgg tgcagatagt agtagttccc caggggagaa
    24961 cagcacggct taactgctcc ggaatcatca tggtgctctc cacatgcatg tggacatcga
    25021 taaagcctgg aatcagataa gcgtcctttc catcgtaaat ttccctggag gggcaggccg
    25081 tttcctgtcc ctcctcgcgg acgcggacta ccactccgtc taaaatatca acctgagccg
    25141 gatagatctc gccggtgaag atattcagat aacggacgtt ggaaacagtc agatcgcagg
    25201 ggatttcctg cagagccgcc ttcatcaggc gggaacggtc tttttctttc tttgcgtaca
    25261 taaagtctcc tttcagccgc cgcataggcg gcagaacagt aatttaatta ttagtataac
    25321 ttatcaaaag gaacggaatg aaatgataaa tgaaccgatt cattttccat ttctatcatc
    25381 atagaaaaaa agaagaccat tgtcaatgaa tttagataaa atttcaaaaa tttattgaca
    25441 tataagggaa aaaggtgtag gttaacagag tggaaaatat gggggaaaag aaaaaatgaa
    25501 ccgattcatt tgttgggagc ggaacatact cctgcggctt atttattagc gcagcgaatg
    25561 aatacggccg ggaaaatacg gccgggaaag gaacaggaaa gagccatgga acaaaaatcg
    25621 accctcagag atgtggcgca gcttgcagga ctttcggcag gtacggtttc caaatatctg
    25681 aatcatccgg aaagcgtgca ggaaaaaaac agaaagaaga ttgagaaagc gatccggctt
    25741 ttgaactaca cgccgaatgt cctggcccgg aagctggcca gcggccgttc cagagtactg
    25801 ggactctgca ttgtgacaga gccggagatt tcagactcta cctggcttca tctgctcccc
    25861 atgattcaga cgctgaatga cagcgcctgc caggcaggat atcagcttca gatcggtttg
    25921 agctccgtag ggagagagga acagacgctc caaatgctga gagacggcgc ggagggaaag
    25981 ggcatggacg gcctgtttct ggtgtcggca tgggaagtgc cagaggattt gatccgctat
    26041 cttctgaacc gggagtttcc ttttgtgctg gtggaaaacc acagccgctg tctggaaaac
    26101 cgccagttct attttgataa ttatgggatc ggcgtctcct gcacagaata cctgtctggc
    26161 ctgggccacc gggagatcgg atttttccat gcgggaggaa gccagcagca catggcggat
    26221 cggtatcagg gctacctgga tacgctgaaa cgtctggggc tcccctggaa agaggagttt
    26281 accagatatg gagattattc cattgagagc gggttttgct gcatggagga gctgttttcc
    26341 atggaatgcc gccctacggc cgttatctgc ggaaatgaca acatggcggc cggagcgctg
    26401 cagtttctga gaaagcgggg gctttccgcg ccggagacgg tttccctcat aggcgtggac
    26461 gacagcattg cggccagggc ggccagtcct gccctgacca gcgtgcatct gcccatggct
    26521 caggtggcga aagaggcggc ccaggcgctg atccgccaga ttgaagaggg aaaaacggca
    26581 gagagcagaa aattttcctg caggctggtt gaaagagaat ccacagcgcc gggagtaagc
    26641 caagctgccg ggaacagcaa aagatgaaaa caagagatca gggaggatga aaatggaaga
    26701 gttttttaaa ctgcgggagc gaaagaccga tgtgaagacg gaaattctcg caggcattac
    26761 tacgtttatg acgatggcct atgtgctggc ggtgcagcct tcggcgattg taggctttgg
    26821 ggacgccgcc agcctgacgg acgccaacgg ctatgtgatc agcaagtcgg ctatccttat
    26881 tatgtgcgcc cttgtcagcg gcgttatcac aatttttatg ggactttacg cgaactttcc
    26941 cttcgccctt tctacgggaa tgggaacgaa cttcctgtta ggcgctcttt tgcaggacgg
    27001 aagcctttcc tttggttcca ttatgagcat tatcctgatt tcaggaatta tttttctggc
    27061 tctgaccatt tttggaatca gggacatgat tgtgaagatg atccccaaga atattaaggt
    27121 ggccatctcg gcgtccatcg gatttttcgt agcgtacctg ggctttaaaa atacgggaat
    27181 cggaaccttc actgacggca ttgccatggg tgatttcaca gacccaaagg tgctgctggc
    27241 tatcgcggga ctgcttttaa tttccatttt aacggcgtac aatgtgcggg gcgcaatcct
    27301 tatcggaatc atagcgatca ccatcgcggg cattcccttc ggagtcacaa agcttccaga
    27361 gcatttcttt gagattcctg atatggccaa tctgggaaat gtgtgcttta atttcgattt
    27421 taagcatctg ctgacagccg acacggtgat ctgggtattt gtagccttct tcggagattt
    27481 cttttccact ctggggacag ttctgggagt ggcaggaaag gccaggatgt tagacgagga
    27541 cggaaacctg cctggcattg aaaagccctt cctggtggac gccattggaa cctgcgtggg
    27601 agctgtgacc ggatgtacga ccattaccac ctttgtagag tccacctccg gcgtggaggc
    27661 gggaggacgt accggcctga cggcagtcac cacgggaatt attttcctgc tgactatttt
    27721 tgccgctccg ctgtttgtca ttattcctga cgcagccaca ggcccggcgc tgatttttgt
    27781 aggctttctg atgatcagcg gcttctctga aatcgacttt tccaatttcg acgacgcctt
    27841 cggtccgttt atcatgattg tgttcggaac ctacacagcc aacattgcca caggaattgc
    27901 agctggaatt ctggcccatg tgggaattaa ggcggctacc agaaagtgga aggagatcca
    27961 tccgggactc tatattctgt gcattccgct gattctctat tttatttata attagaatgg
    28021 atataaaaag gatccgatcc ttcatctcat atctgaggtg gaggatcgga tcctttttgt
    28081 aatttctgga acagacgatg gatactaagc gttttagtcc gttacctggt ggttcagcca
    28141 ttttccgctt ctgaaccggt ggataaagaa caggccgcgg accgtccagt cggtgaacat
    28201 gccgatccag actgcaatag ggccgaagcc gcagacgcgg atcaggtaaa tgcagaggct
    28261 gacgcggcag atccacatgg agaggcagga gagaatcatg gaaaatttca cgtcgcctgc
    28321 cgcacgcagg ccgtagcctg gaataaaggc ggcagtccat accaggggtt ttacaatggt
    28381 aatccagctg ttcataaaca gacagaggga tgcgctctcc ccggaaagtc ctgccagctt
    28441 tgtgataggc ccagccatca ggaaaatgag aaggcagctt ccaaagacca caaactccgc
    28501 cgcaaagctc agctttttaa tatagtagcg ggcttcgtcc ggtctgcctg cccccaggca
    28561 ctggcccacc accgtcatca tgccgattcc aatgccgatt ccagcaattc cgttaaagtt
    28621 ttccataata tttgtcatgg cctgagcggc gatggcggtg gttccaagag tagaaacggt
    28681 ggactggatt gccagctttc caaactggaa catgccgttt tccacgccgg acggaatacc
    28741 gatccgcagg atatttttga taaggcgtcc gtctggtttc aggaagatga agtttccaat
    28801 ccgcagttcc cctgatttcc tgcgtaggaa gagaagcacc agaagggccg cagcaatgcg
    28861 ggaaagcagg gtggagacgg cggctcccgc cacgcccagg tgaaagcccc agattaagag
    28921 ggcgtttcct gcaatgttca tcagattggt ggacacggta atcgccatag ggaggcggct
    28981 gttgttctgc gcccggaaga cggcggatcc ggaatcaaaa agcgcgataa aaggaaagga
    29041 cagagaggtg tagaaaaagt acaccatagc ggcgtccatg acctcctgtt ccacagagcc
    29101 gaaaaccaat cggagaagag gcgcccggaa cagctggcag actgccagca cagccagaga
    29161 gatggcgaaa ataataaaca gaagctggtt ggcagagcgt tccgcctgat cccgccgttt
    29221 ctggccaaga tagttggcac agacaatggc acctccggag gccagggcgt aaaaggcctg
    29281 gatcaccaaa atattgatgg aatccacgag ggatacggcg gaaatagctg cctcgctcac
    29341 attgctgacc atcatggaat ccacggttcc cataaaggaa gtgaaaatct gttcgcagat
    29401 cagggggagc atcagggcaa tcagctgccg gttggaatag agatggggct tttttgaaga
    29461 agcccggacg gcgtgtttca taagatgtca ccttcgtttc attagagtat tcagtaagga
    29521 aattgtataa aaatccagca cctattttaa tagaagggac ggcagagttc aactggcgga
    29581 aaagaaaaat gtaataaata aaaacgataa atcagattaa aaatctgtta caatataaaa
    29641 tatcaaataa tagacggctg ttttaatgga cagaatgaga aaacaggagt gcagaaagag
    29701 gaggggggca tgaaaatgaa gcggaagcat ttgctttgct gtctgacagt ggcagcaatg
    29761 ctgggaggat gcgggccgga gagcctggag aaaacacccc aggaaaggca gacgcagacg
    29821 gcggatatgg ctcagaatgg aaaaagagag agtgggacaa aacgggaaac aagtgggaac
    29881 gaggggcaga gcgaaagaga ggaaaattct cagtttgctg acggattcgg gctgattgag
    29941 gaggaaagtc ccagagtgta ccagctggca gaagaggata ccccctttac cgaatcagcc
    30001 cttgccaggg ccgatttggt atttgcggca cagcaggagg ggaaattctg gtttacagcg
    30061 gtgatcacag attattctgt ggaggaggca gacgaggaga ctgcgccgag ggagatagat
    30121 cataatcctg cgtattttaa aatagaagag acaggagagt ccgggcagga gacattctat
    30181 ggatacagtc cttatctgga gcgaatcaat gacacagagc agacagagcc ggtgcggata
    30241 gaggggacaa atatagagaa ggccgggtat gctcccggca gactggtgca gaaaacgtcc
    30301 agcctgtcga ggcttccatc cggcagcttt atcatgaatt ttggatattt tatggaggac
    30361 ttctattcct gcccgggaga gccggaagga gaataccgcc tgtatctgcc aggctttgaa
    30421 aatcccattg tgtttgagat ggaggcggct ccggcgctgg aggggaagca ggagcattca
    30481 gaaaaagcgg tttcagagag cagctctgcc tgggaagagt tgggaaaagg aatatcagga
    30541 acggcagaag gagacggata caagcgtggg aaaacccata cagctggcag gaggaaccgg
    30601 cagatggaag cgcaggtgga atccagggaa tgcagatcgt atttgagatg ccggaggaag
    30661 ccaggaagga gcttcagacg ggaaaagcgg gacatttcca ggcggtgatg gaagggatta
    30721 cgctggtggg ggcagatgag tcacagatgg tgaatattcc agttcccagc cctggtgaga
    30781 cgagaactct tgagcagacg gtcagctttc gggactgcca gatccgcctt ctcaaggtgg
    30841 cggcgcagga gaggacagaa gaggagaaaa aggaatccgg aacagacgca gacgttcttc
    30901 ttcatgtttc agcttctgtg acagaccgtt cagagggaca aacgttcacg tttgcacaga
    30961 tagagtggga gggagagcgg aagacggttt cctatgccag aacaggctgg ccggaatttc
    31021 cagatgaagg tgggggagtg cagcctgaaa ccgtgatgac agggttcagc ctgctttcca
    31081 gcggcagcga ggagtctgtt tcagccagga tttacgcccc ttcttactgg ctcccagaaa
    31141 cggttataat accgctcaaa atagataact taaacttata ggaaataaaa cttctggttg
    31201 acgcaggcct gaatttatgt aataatctgc tttgtgactt gcgggaacca ataaaatagc
    31261 agcagtctgg ccatgcagag agcctgacaa aaaaggcttc atgctgaatc gctgcataac
    31321 atgaatgttt atttcttcaa ttactatgtg gagaactttc ctgcaaaacc tcatggatgt
    31381 ggataccctg ccaaaagcgg ggaatcctaa aaggcagaaa ataaataaca agaagaggtg
    31441 ttgaatggaa aattcaaaga aaatcgactg gtataccctg tccttcatgg cgttttccac
    31501 agtctggggc tttggaaacg ttctgaacgg cttcgtatac tttaacggaa tcgaggttat
    31561 tttcagctgg attctgatgt tcgtgctgta ctttatcccc tacacgctga tggtaggaga
    31621 gctgggatct gcatttaagc attccggcgg cggtgtgagc tcctggatcc gcgagaccat
    31681 caatccgaag tttgcctact atgcaggctg gacctactgg gcctgccacg taacctacat
    31741 tgccagcaag ggaagcggcg gcttaaaggc attaagctgg atggtattcc agaacggaag
    31801 cacatatgac cagtttccga cgctctgggt gcagatggct acgctggctg tattcctgtt
    31861 cttctgctgg gtggcgagcc gcggcttaaa tccgcttaag aagctggcta cactggctgg
    31921 aaccagtatg ttcatcatgt ccatgctgta tatcctgatg atgtttgcag cgcctgttat
    31981 caatcctaat gggggctacg tttccatgga tttcagcgta aagaacctga ttccgcagtt
    32041 taacgtgggt tactttactt ccttatccat cctggtattc gcggtgggcg gctgtgagaa
    32101 gatttctcct tatgtaaata aggtgaaaaa ttctgctaca ggatttccca agggaatgat
    32161 cgctctggcc atcatggtta tggtctgcgc tattttagga accatcgcta tgggaatgat
    32221 gttcgatccg gccattatca acgagagcaa ggaaagcttt gattcctatg tttccaacgg
    32281 atcctactgg gcgttccaga agctgggcga gtattatcat gtgggcaatc tgttcctgat
    32341 tatctacgct gcctgcaacg cagtgggaca gttctctacc cttgtgctta gtatcgacgc
    32401 tcctcttcgt atgctgcttg acaatgagga tgcaagagag ttcatcccgt ccaagcttct
    32461 taagaagaac aaatacggcg cttacattaa cggaatctgg atggtagtcg tattatctgg
    32521 aacgatcatt ttagtacagt ccttcgttcc aggtgcagct gccgttctgt cccagctgaa
    32581 caagttaaac tctgttacca tgcctctgcg ttacctgtgg gtatttgccg cttacattgc
    32641 actgcgcaag tatgtgggca aatttactcc ggagtaccgc tttacaaaga accagggact
    32701 tgcctttaca gccggcatct ggtgctttgc agtaacagca gtctgctgcg taatgggaat
    32761 gtatgtagag ggcgatatgg cgtctactgc gttaaatatc attactccat ttattctgac
    32821 tgccctcggt ctgatccttc cgatcatcaa gaagagagag acagagcggg caagctaact
    32881 gaacaaaagc ctgaaccatg agtgaaaagg gccgctgcaa aagagacacg agtttctgag
    32941 agcagcggcc cttttaatat gacgctttgc agctatgcgg actttcgtac ttacgatatg
    33001 gtaaaaacgt atctggccgg ttgcgatata tttaagaata ggtcttgatg atctcctctg
    33061 caatagttcg tttggtaaca cagcgatcca ttgcctgttt tcctatgtag cggtgagcct
    33121 cagattcgct catggaaagc tgactgatca aaatccactt tgccttattg acaaggcgga
    33181 tttcatccat tttttcttca atggataggg attttttttc aaattgtctt agccgttctc
    33241 tggagctttc cagccagtta agcgcatatg tcatagttat tttggataat ggctttgaca
    33301 aggtaaacac accatattcc gtaacctgct catgaatccc attatagata tcgcttttta
    33361 cgatgagaag aacaacagat tgcttattac aacaagtgtc aatggcaaaa cgaacgccga
    33421 tatcatcgcg taaaggggcg ttaatgataa tgaaatcata agttttttct gtcagcgtac
    33481 atctggcggc attgatactt gaaacagtat gaaca
//
LOCUS       DBMDUW010000025        32411 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1072_length_32411_cov_5.059115, whole genome shotgun sequence.
ACCESSION   DBMDUW010000025 DBMDUW010000000
VERSION     DBMDUW010000025.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 32411)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 32411)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32411
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1072_length_32411_cov_5.059115"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(1..523)
                     /locus_tag="ACZPCR_06505"
                     /pseudo
     CDS             complement(1..523)
                     /locus_tag="ACZPCR_06505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008975858.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            654..860
                     /locus_tag="ACZPCR_06510"
     CDS             654..860
                     /locus_tag="ACZPCR_06510"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230563.1"
                     /translation="MAATRLIALHINKGKTVAQCLADRTDYSENAAKTEDGKYISAYA
                     CDAKTCDEEFLLSKRQYEHITGRT"
     gene            870..1694
                     /locus_tag="ACZPCR_06515"
     CDS             870..1694
                     /locus_tag="ACZPCR_06515"
                     /inference="COORDINATES: protein motif:HMM:NF015397.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HIR1230564.1"
                     /translation="MIAYQIRQSFKPGEITPEEANKVRYETAMRFTNGKHAFIVATHV
                     DRAHIHNHIIFNSTTLDCTRKFCDFHLSGLALARLSDIVCLKHRLSVIIRKPYGERQK
                     RTEYPEKKSQRDEICEAIDATLARKPKDFRELIGILQEAGYEYKDGKQPALRGKGHAR
                     FARFRSLGKGYSIEELCEVIAGNAVHKSKFAEKTRTSARFAQVHQRTELSFLIDIRAK
                     MQAGKGAGYARWAKVFNLKQMAKAMMFMEEHGIKSNVELKEKAEEISENAMRCWNL"
     gene            1712..2119
                     /locus_tag="ACZPCR_06520"
     CDS             1712..2119
                     /locus_tag="ACZPCR_06520"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230565.1"
                     /translation="MSEVSVLRKHLINYAKTKDVFAAYKASGYNREFYEAHRDTLALR
                     SAAKKAFDAYKKENGSDKKLPRISELNAEYAMLLQRKKSAYAEYRKTKSEMQDWLVAQ
                     KIVQEILKEDEQKKEQLHEREVRQEEENRQSSR"
     gene            2285..3244
                     /locus_tag="ACZPCR_06525"
     CDS             2285..3244
                     /locus_tag="ACZPCR_06525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008755226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HIR1230566.1"
                     /translation="MEYLNKVLGVKVTYEDVEFKHLPNFIVTRYRLQMVSMNEKKVVL
                     LYPKTELEQIEVLKKHIARIQKNENLPVVLVLKELSFRQKEYLIREKIPFIVDGKQIY
                     LPFMAVYLQERCSAEKIPRKEILPSAQMLLLHFIYGGAQELSTSQAAKDLELTPTSIS
                     RASRQLEEMGLLHIRKAGVQRIMQSEDSPKTLFQKAGDKLLNPIKRTVYIPKELVGTE
                     LLESGYSALAEYSMLNTPNVRCYAAERISQWKDAMINNLQDSQVQVAVEMWRYNPRKL
                     SARNVVDELSLALALREDADERVEEAVEEMLNELWRKIDGYRN"
     gene            3228..3986
                     /locus_tag="ACZPCR_06530"
     CDS             3228..3986
                     /locus_tag="ACZPCR_06530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015529064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230567.1"
                     /translation="MVTGIDSFREWFKGSEEQYAIIGGTACDILMTEEGLDFRATKDI
                     DLVLIIEAVDANFGKKFWKYVKQAGYEHCNKSSGVPQFYRFSHPISNQYPAMIELFTR
                     KLDTIQLPEDAVLTPLPMDDDISSLSAILLDNDYYEFLKQGKVVVDGVTILDAAYLIP
                     FKAKAWMDLADRKAAGEHVDSKNIKKHKNDVFRLTELIDPTAKIVAPKGVYADIQEFV
                     QRMKNENVDIKQLGVVGRTKEKILEELKVMYETV"
     gene            4039..5133
                     /locus_tag="ACZPCR_06535"
     CDS             4039..5133
                     /locus_tag="ACZPCR_06535"
                     /EC_number="3.1.1.106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013274280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyl-ADP-ribose deacetylase"
                     /protein_id="HIR1230568.1"
                     /translation="MPLQITRNDITKMSVDAIVNAANTSLLGGGGVDGCIHRAAGLEL
                     LAECSTLHGCETGSAKITKGYHLPCKYVIRAVGPRWRDGKHREQELLQSCYRTSLNLA
                     KENGCQSVAFPLISSGIYGYPKDQALRVAVDTISMFLMENEMMVYIVIFDKKANEREH
                     NYFNNLLKNSKTAKKQIALYLDEAKVERIDKIIKIFSSLSDSKSFSRNTLIEEAIDKF
                     IGESEQFLYDEHGIDVERLLEEERAEKYDTVVFSSSGRGFEETFLGESEPACWYPCKV
                     SDSREGSLKYIAVYRGRLVSAITHYAKIKEFKYDSEKKCKVCYFDGDPIELPTKIRLG
                     NKDSCFFIGTKYTSLESLLNASQADEVAFG"
     gene            5375..5872
                     /locus_tag="ACZPCR_06540"
     CDS             5375..5872
                     /locus_tag="ACZPCR_06540"
                     /inference="COORDINATES: protein motif:HMM:NF024803.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HIR1230569.1"
                     /translation="MKKTSEISRIAGISKRTLQFYDDEGVVKAERSGSNYRLYDERAL
                     GELWEVMIYKEAGMELKEIKQLMRAPEQEKKLFYQMYIKSLEEKIKRLEGQREWISFI
                     MTHGFPKVPENEEGVTYKERIAELSCRETGGEAGSCRKTAGESSREEKLKDLRNPAEK
                     TVRYF"
     gene            complement(5927..6193)
                     /locus_tag="ACZPCR_06545"
     CDS             complement(5927..6193)
                     /locus_tag="ACZPCR_06545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009268303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1230570.1"
                     /translation="MKNHDSIDRIIQVNDTNIGKNIAKIRKSMKIKQTDMAARLQIHG
                     IDISIYSYNRIEKGTQNPTVSFLYACCHILECDMNAIFRFSEMV"
     gene            6303..7490
                     /locus_tag="ACZPCR_06550"
     CDS             6303..7490
                     /locus_tag="ACZPCR_06550"
                     /inference="COORDINATES: protein motif:HMM:NF014036.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcjF family protein"
                     /protein_id="HIR1230571.1"
                     /translation="MEKGNVLVIGNSGVGKSTLINAVLGEEKAKTGCGTKGTTEYLEI
                     YESDEVPFRIIDSVGFEPSFIKKRQAVHAVKKWSRESAKKENENRPINVIWFCVDGMA
                     KKLFSDTIKSLSSATSMWESVPVVVVITKSYGIPDREENVRMVYSAFAQQKRYSKNLR
                     KVIPVVASAYVLNESAYAPPEGISELIDITNELMPEGIKAAEKDIYQFKLSRKRALAQ
                     GIVSVSTTAGITVGAVPVPLADAFILSSIEVAEINALARVYGINKNEESKHFFNSIVE
                     AGTVSAAARGAISALKGIPGVNLAAGLVNAVIAGSFVAAIGEGTIYAFEQVYLGKKTV
                     KDIDWVTKAVESRLSTEFIDKVASAVRQITENTDKNAIGKVILDLFGEKEKQPGCNGK
                     GRR"
     gene            7500..8075
                     /locus_tag="ACZPCR_06555"
     CDS             7500..8075
                     /locus_tag="ACZPCR_06555"
                     /inference="COORDINATES: protein motif:HMM:NF025380.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4230 domain-containing protein"
                     /protein_id="HIR1230572.1"
                     /translation="MGNIHKNRKLILAAALVLAVLVVGSLFGPNVMNKIGKENVITSS
                     QLEKAIDISQLSTAEFVYNGIAEKYDDDKPEKVECYIAYHADVKVGIQMEDVEFEIDE
                     ENKTVTPILPEISVNIAALDENEISYIPKNPDIPLKEIIVLCKEDAVREANDSKKLYQ
                     TAEENLKAVIEALVSPILEHAGYTIKWQSVS"
     gene            8088..8675
                     /locus_tag="ACZPCR_06560"
     CDS             8088..8675
                     /locus_tag="ACZPCR_06560"
                     /inference="COORDINATES: protein motif:HMM:NF025380.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4230 domain-containing protein"
                     /protein_id="HIR1230573.1"
                     /translation="MKRKTNRGIRMLAVLAASGVCLTGCAEKKKEADFSGINSVCELA
                     TLKCYYHNVAKGETKASGLLKWFGTGYKKIWTEYSGIVELGIDVNKVSVSSPGADGVV
                     KITIPDAEILNVDLDEDSMGEPLTDTGFLTEITKEEETAALAEAQDNMEETAKKNSAL
                     LAQAKERAKNLIEGYVKNVGEQIGEEYTIEWEEIE"
     gene            complement(8939..10003)
                     /locus_tag="ACZPCR_06565"
     CDS             complement(8939..10003)
                     /locus_tag="ACZPCR_06565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008706250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HIR1230574.1"
                     /translation="MTFYQELQLNSAGSKTLIRITEDKKERRRHILIYNFKVYLVVAF
                     CFAAVTLFSMVFGSENSIAGVAVLLALLVLRQADFGIHTSHGLLCIAGIFSILMAGPR
                     LTNAVSPFTAFFINLICILILMFLGCHNILMSNHSTFVLSYLILQGYDVTGHSFVMRT
                     AGLFFGMLLCMAVFYKNQRHRVHKRNFSHLFQEFNPFSLRNRWYIKLTLCLSTTLLIA
                     SLLGLPRAMWAGIACMSVCLPFEKDMVKRAKERGVFNLVGSLIFLGLYLILPADLHSM
                     LGLIGGIGVGYSARYPWQTVFNTFGALSIASGVFGITGAVILRIGLNAAAALYTVAAG
                     WLFDRVFNRLSERIACEKAA"
     gene            complement(10105..11436)
                     /locus_tag="ACZPCR_06570"
     CDS             complement(10105..11436)
                     /locus_tag="ACZPCR_06570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1230575.1"
                     /translation="MTRDMTQGNITGHMLSYAVPLVFGNLFQQLYHTVDSVIVGQFNG
                     KEALAAIGSAGPVMNILIFLIVGISMGSSILMAEYFGAKDYESLRKEMATSLTAGFLL
                     TAVLTVVSVCGSGLFVRFTRTPAEIAPLAADYLRIVSAGLFFTFLYNILAAGLRAVGD
                     SKAPLYVLIFTTAVNVVLDLLLVGVLGMGVCGAAIATVSAQAASALALLGCLFFRARF
                     LWVPLSEMRIERKFLKKTIDYSSVSALQQTMLYLGRLLVQSGVNSLGVDAVAAFNAVS
                     IADSYILAPGDSLAASMTTFAAQNKGAGTRDRIGKGLKTMLCIAELYVCLAAVIVFTQ
                     SRWILGIFLKPQETSALAFGLSYLLPMSWGYILTGITNTFQGYFRGIGNLKITLWATL
                     IQIPIRVTVTYLLLGALGLQAVAVGTIIGWICMAVFQYFCCRKWGIHETGS"
     gene            11670..12773
                     /locus_tag="ACZPCR_06575"
     CDS             11670..12773
                     /locus_tag="ACZPCR_06575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HIR1230576.1"
                     /translation="MKYMDYILETLERIVNTPSPSGYTKEVMEIIRREAENFGFQTEF
                     NRKGGLIITVPGQTEHVLGFSAHVDTLGAMVRSVRSNGTLALTQIGGMMMEAIEGSYC
                     QILTRDGRRFTGTIQTKEPSVHVWDDCKEFKRTEENMEVRLDEIVRTKEDVEQLGIGA
                     GDFISFDPKFVITESGFVKSRHMDDKASAAVLLGLLKYVHDTGKKPEQTLKLLISNYE
                     EVGHGCSYIPQDVEELIAVDMGCVGDDLNGDEYRVSICAKDSRGPYDFDMTNRLIGLA
                     KEYGIGYMVDVFPHYGSDVSAALAGGNNIRGALIGQGVSASHGQERTHVKGLMETFKL
                     AAAYAGLLNKEEAETVFADFKGVQALDSEKSGR"
     gene            12777..13499
                     /locus_tag="ACZPCR_06580"
     CDS             12777..13499
                     /locus_tag="ACZPCR_06580"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HIR1230577.1"
                     /translation="MQAVLLAGGLGTRLRSVVSDRPKPMALIEGRPFMEYVIRGLARH
                     GITDIIFAVGYKGSMVEEHFKDGTDMGIHVSYAYEEELLGTAGAIKNAGKFVTEDQFF
                     VLNADTFYQLDYSRLTALAGEKNLDMALVLREVEDVSRYGAATLENQMLTGFNEKLKA
                     ADGEEKRPGTINGGVYLLKKSLLDEIPEGKVSLEQEMIPRWMKEGKRLGGFVNDGYFI
                     DIGIPEDYFRFQEDVKKGVVQW"
     gene            13493..14563
                     /locus_tag="ACZPCR_06585"
     CDS             13493..14563
                     /locus_tag="ACZPCR_06585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003524189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GHMP family kinase ATP-binding protein"
                     /protein_id="HIR1230578.1"
                     /translation="MVIRAKAPLRVSFGGGGTDVEPFCVEQGGAVIGSTINKYAYCSI
                     IPREDDQIIVHSLDFDMTVKYNARENYVYDGRLDLVTAALKAMDINKGCEVYLQCDAP
                     PGSGLGTSSTVMVALLSAMAKWKGIEMDGYGMADLAYGVERLDLGIAGGYQDQYASTF
                     GGFNFIEFHGRNNVVVNPLRIKKDIIHELQYNLLLCYTGNIHVSANIIKDQVNNYKKQ
                     DAFDAMCEVKALAYAMKNELLRGNLHSFGKLLDYGWQSKKRMSSKITNPQIDELYDEA
                     KKAGALGGKLLGAGGGGFLLMYCPYNVKHKVAARMEAVGGQLMDWNFELRGVQSWCCD
                     EERWKYDEVKVQMPNRDYTFHI"
     gene            14579..15196
                     /locus_tag="ACZPCR_06590"
     CDS             14579..15196
                     /locus_tag="ACZPCR_06590"
                     /EC_number="3.1.3.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034200 - D-glycero-beta-D-manno-heptose
                     1,7-bisphosphate 7-phosphatase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-alpha-D-manno-heptose-1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HIR1230579.1"
                     /translation="MPEKGIKTVFLDRDGTMNVEVNYLHRPEDLRLIPGVPQAVRQLN
                     EAGFCVVVVTNQAGVARGYYGEEDVKRLHQYLNEQLKAEGAHVDAFYYCPHHPEHGIG
                     PYKRECRCRKPGIGMFEEADRDCPVDRERSFMVGDKLIDTEAGHRFGVRSILVGTGYG
                     AEIRRQEAARGDSGEAAGYDWYAEDLKAAADLICRLDREQNGEAD"
     gene            15198..17606
                     /locus_tag="ACZPCR_06595"
     CDS             15198..17606
                     /locus_tag="ACZPCR_06595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter KefB"
                     /protein_id="HIR1230580.1"
                     /translation="MEKNRIMEAFLSLGLLVLAVLCVAVPFFVLFTGDGTYSWQFGDP
                     ATKKMMAEIALLFVLLSGILLLGKRPAVRWGKTALVCLIFCWGHVIFLPMTVSALYLG
                     YVILAGRFVRTVLLGQKEIEDGWMADFILGVSAVLCAFCLLSAFKTGSIAQLRLFSAA
                     SGAALYLWAALSGGFGRAAAWLKDSARRDGFRKEGLQKAEFQKKEFQIEGFQGKNRTL
                     WALLTAFIIVMILVQAGRMNISLDFDTLWYGVRSEYVLDNGTGIYENPGMVGMAYVYA
                     KGLETLALPLSDLASHSYLLALNLWIAAAGLMGIYRLAGLFMNRTWALAAAALSSCIP
                     GIMNMAISAKPDVITWVIQIFMVYYMACYIKNRKFALLALSGGAYLLSLTMKSTALVF
                     STAVFGMSGLYLLGRRLLSLRAPLRQWLLLAAPAGALTGIWARTMMITGMPVTSVFTS
                     IFAVLGFQMKYPFATSGLPQNYEEASNLAVLLRRLFHMLLMPTGKDMGHVVFAWGSPL
                     MLFLTGACLAAALLMAAAWKRRRAGESGGQPDRKQNRESAKKRLSLYAHVAFWPFLAV
                     NLVSLVMLYQIDGNYFMLLYTGIIIGSLSLLHSLKQAGHRRFLRTVSWLLVPIMAFNV
                     LMTAESNWAWSLGFSEIQWANKGRVNHEALQHEKMVQAGNEQIWNILAEDETTRVIAF
                     GDHPGCLQFPCVVQSYKDITSPWGNVELVNTVEAFEEYMAYAQADYAYVEAGFIGEGN
                     WEWSYGLVRRMIERGTLTDLVFEHGNVLARVDLDGVSSMETRENLRLFDENYITYERK
                     QGGK"
     gene            17608..18258
                     /locus_tag="ACZPCR_06600"
     CDS             17608..18258
                     /locus_tag="ACZPCR_06600"
                     /EC_number="5.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006778527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008968 - D-sedoheptulose 7-phosphate
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-sedoheptulose-7-phosphate isomerase"
                     /protein_id="HIR1230581.1"
                     /translation="MQERKEYRYLDQLTERYPCLSAIRPELEKAYETLRECYAKGGKL
                     LAAGNGGSCADSEHIVGELMKGFVKRRELPEEMKAALKQADPALGEELSGCLQQALPA
                     IALTGHAGLSTAFANDVNADMAYAQQVMGYGNEGDVFLGITTSGNSLNVRYAAAAARA
                     KGMKVISLTGRDGGKIRELSDICLIVPEQETFKIQELHLPVYHALCLMLEDCFFES"
     gene            18275..19654
                     /locus_tag="ACZPCR_06605"
     CDS             18275..19654
                     /locus_tag="ACZPCR_06605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008396575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230582.1"
                     /translation="MNEKLGKRLLYLGVPAAGIAFCLYYLSIATEDVAYTDYMRLIVS
                     YLPDVANPAKFFVPDVLTRVPITYLGRIINVALFHYSTVFDMVLGVLSHGLAALALAS
                     YCRDKKGYAPWFLVIMLLMFSLNKWEMLGNGSGWVCFLSIAGFYWNFVILDRTVCGRE
                     RKYDRVLLKALPAFLTLLVAGPYCGSYSLIMTMAYCALLVSDYRKNRRINKEWAADLA
                     FVLGALGLYLLSSHFAVYEYRGATEATLLSTLVSNPEFFVKFILEAFASPIIGIEVVS
                     NVIKTSAGVCLLGAVVIFFYLLALWMNVKYRLWERTILPLMLILIGGVNHALVLYSRW
                     IFLQENYGMASRYAIQYEMGIFGILLTFAAVFALKRERRQVLAVLAGGFICLLLAGNF
                     YTTREELLKAPLRKLSLEQTIETALDYRNKTDEELGAQLHTNGERARKALEILDKNNL
                     NIFYQEGAE"
     gene            19654..21315
                     /locus_tag="ACZPCR_06610"
     CDS             19654..21315
                     /locus_tag="ACZPCR_06610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
                     /protein_id="HIR1230583.1"
                     /translation="MKRYTKYAYLAVFAAFYVFLLMQFGNVFIYYDDYGYLSLSYGTN
                     IDVAGAEYSFSELLAFMKGHYFNSNGRLLYMFLYCFVHMLGGIRGVQVFMATAVLAVA
                     LLLFFTARRMLEGRLEAEKVSGDGTKEEGGELQGRLSPGALAALAAFLCLLYGTLGIM
                     VQRMGTYWYAASFIYVVPAITFLVFALYFYRTVFLPKGEKPGVLRMCLCAALGFLAAW
                     SQEQWFVTTISFVVICLGVKLWRDRRLELYEILTFLACAAGGLIIILSPAVSARMNSA
                     GNAEFASLSLFGKLGRNIPLLMNLFFSGENIRYLMFFFPMMIFMGCMAAAKDRKLLPL
                     HLGFSAVSAAVFAGVFLKQKLHVFAPGTYSALTANLLLLYIAFCFAEVILFYRAEKQI
                     FGSAVFAAAVLSVGSAAIVPEVPLRIFYPFLYLSWLLFAYLYGRILLIEARRIPLSAA
                     CTLVFLAMISIPNLKSIYTGYKMNYQVLMYDDAVFKESAEAIRQGADIETIEVYELPD
                     LLCKNEVVYDENFSFMIAWMRQYYDLPEYVEFEYRPLSSMEDLRQ"
     gene            21384..22160
                     /gene="rfbF"
                     /locus_tag="ACZPCR_06615"
     CDS             21384..22160
                     /gene="rfbF"
                     /locus_tag="ACZPCR_06615"
                     /EC_number="2.7.7.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007717315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047343 - glucose-1-phosphate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate cytidylyltransferase"
                     /protein_id="HIR1230584.1"
                     /translation="MKVVILAGGFGTRISEESHLKPKPMIEIGERPILWHIMKHYSQY
                     GFHEFVICLGYKQYVVKEFFADYFLHTSDVTFDLANNQMEVHNNYAEPWKVTLVDTGL
                     HTMTGGRIKRIKDYVGDETFLLTYGDGVSDVNLDELLKFHRQHGKIATITGVNVGQRF
                     GVLEVDDQGAITAFREKNDDDGKIVNGGFMVMEPKVFDYIEGDSTVFEKAPLEHLAAD
                     KELMVYRHNGFWHCMDTQRDKNHLEEMWQSGRAPWKTWEN"
     gene            22169..23230
                     /gene="rfbG"
                     /locus_tag="ACZPCR_06620"
     CDS             22169..23230
                     /gene="rfbG"
                     /locus_tag="ACZPCR_06620"
                     /EC_number="4.2.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009216201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047733 - CDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glucose 4,6-dehydratase"
                     /protein_id="HIR1230585.1"
                     /translation="MTNPIFDFYRGKRVLVTGHTGFKGSWLCEILLLAGAQVTGYSLN
                     PPSDPSLFELLGLSERMDSRIGDVRDLAHMKQVFEETQPEIVLHLAAQPIVRESYKNP
                     VYTYETNVMGTVHLLECARLCPSVRSLVNVTTDKVYENREWEYGYRETDRLDGYDPYS
                     NSKSCSELVTHSYVKAFFGEETSPAVSACRAGNVIGGGDFAADRIVPDCIRAMQKGEE
                     IAVRNPYSTRPYQHVLEPLYLYLTVAMRQYEDRSFAGYYNVGPDDEDCIATGELVDLF
                     CGFWGGEARWENRYDGGPHEANFLKLDCSRVKKTFGWRPRYHVSQAVEKTVEWTKEWL
                     SGGDVRACTDRQIEEFFMK"
     gene            23262..24593
                     /gene="rfbH"
                     /locus_tag="ACZPCR_06625"
     CDS             23262..24593
                     /gene="rfbH"
                     /locus_tag="ACZPCR_06625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein RfbH"
                     /protein_id="HIR1230586.1"
                     /translation="MNEKEARSQILSLVADYCREFHNKKEAFKEGDRIPYASRVYNED
                     EMVNLVDSALEFWLTSGRYTDEFEAELARYLGVRYCSLVNSGSSANLLAFMALTSPLL
                     GERRICRGDEIITVAAGFPTTVTPAIQYGAVPVFVDVAIPQYNIDVTKLEAALSEKTK
                     AVMLAHTLGNPFDLKAVKAFCDAHGLWLVEDNCDALGSRYEIDGEMKFTGTIGDIGTS
                     SFYPPHHMTMGEGGAVYTDNALLNKIIRSFRDWGRDCVCPSGCDNLCGHRFDRQYGEL
                     PLGYDHKYVYSHFGYNLKATDMQAAVGCAQLKKFPSFVERRKHNFARLHKALEGTEDR
                     LILPVACEHSDPSWFGFLITCKEGVDRNKVVQYVEERGVQTRMLFAGNLIKHPCFDEM
                     RKTGEGYRVSGTLENTDRIMADTFWVGVYPGMTDEMIDYMAKTIREALTQA"
     gene            24634..25473
                     /locus_tag="ACZPCR_06630"
     CDS             24634..25473
                     /locus_tag="ACZPCR_06630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HIR1230587.1"
                     /translation="MEHWDLTRVHEANLKLLKEIDRICRKYKIKYMIDSGTLLGAVRH
                     QGFIPWDDDADVIFTRPNYEKFLKVAGRELPEGMTLLRPEDIRGGKVFYDFTTRIIYD
                     NSRVHEDNEQMQFYEGKLNHIWVDLFIIDRLPESRFGAFFAKFLQKVVYGMAIAHRDR
                     IDFSKYSLADKIRVGTLSAAGRLVPMPVLFRLQTALAAKDRNKRTGKRYCSNYQPDFL
                     YVTLDEDWCEKTVDLPFEDTVLMAPEGFEHVLSILYGDYMTLPPEEKRVPAHSSIEIQ
                     ILD"
     gene            25488..26423
                     /locus_tag="ACZPCR_06635"
     CDS             25488..26423
                     /locus_tag="ACZPCR_06635"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006778536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1230588.1"
                     /translation="MKKISIIVSVYNEESALRQFYGESKPIFDALPWDYELLFVNDGS
                     SDGSLAILKEFAAQDPKVKLVNFSRNFGHEAAMIAGIDHFDGDGLVCMDADLQHPPEC
                     VAQIIEKFEEGYEVINMVRTKNKSAGLIKNITSGGFYKVINTISDVKLEPNASDFFAM
                     TANAADVLKQSYREKVRFLRGYVQNIGFNRTNIEYEARARVAGESKYSLKKLFKFSIN
                     TILCFSDLPLKLGIYSGIFVGMMGVLLMIYTIYGRMVHGAPSGYATIVVVMCFMFAML
                     FVIVGIIGEYIAIIFTELKDRPIYIVKETANIEEK"
     gene            26620..27261
                     /locus_tag="ACZPCR_06640"
     CDS             26620..27261
                     /locus_tag="ACZPCR_06640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230589.1"
                     /translation="MRKILVLLACAAVLSGCAPKSNIVSPDSTEGTVAGQPDFDAKDD
                     VEIDWEQAKVDAEDIFTDTKEYPYSVDFHLLLQPEQKEIMLVWVVKDDLPSNQIAKYS
                     EALVKGFNDMVATQDFSIERSSDTSYGGLWKTYGLSYGLAPESTQDDEDTWFISGSYP
                     AGTDFKLPSAEEIQKAVDSVEAADAAETEAPEEEASGNSEEEPAEENEADTAE"
     gene            27566..28462
                     /locus_tag="ACZPCR_06645"
     CDS             27566..28462
                     /locus_tag="ACZPCR_06645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HIR1230590.1"
                     /translation="MKKRVWAMGAAVMMMGALTACAGGSDSKAASTQAEESGTEAGKG
                     AVSESEGDDTETRQAERTDETSEGGTFTVGFDQDFPPMGFVGEDGEYTGFDLELAQET
                     AKRLGLTYVAQPIAWDAKNMELESGNIDCIWNGFTMTGREDEYTWSEPYMENSQVVVV
                     MEDSGIETLEDLAGKIVEVQADSSAEAALKEMPDLTSTFGTLQTTPDYNTAFMDLEMG
                     SVDAIAMDVIVAGYQMQEREGSFKILEESLASEEYAIGFKKGNTELCEKVQQTLEEMA
                     ADGTMAEISEKWFGEDITTVGK"
     gene            28548..29198
                     /locus_tag="ACZPCR_06650"
     CDS             28548..29198
                     /locus_tag="ACZPCR_06650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009662943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HIR1230591.1"
                     /translation="MDLLQIMKQLAGGMGTSIEIFTVTLLVSLPLGLLISFGRMSKNP
                     VLRAAVKFYISIMRGTPLMLQLMVVYFGPYYLFGIRVGNGYRLWAAFIGFAVNYAAYF
                     AEIYRSGIQSMPAGQYEAAKLLGYTKYQTFFRIIFPQVVKRILPSITNEVITLVKDTS
                     LAFTISVMEMFTVAKALASSQVSMVPFVAAGLFYYIFNLLVASFMEYAEKKMNYYQ"
     gene            29211..29969
                     /locus_tag="ACZPCR_06655"
     CDS             29211..29969
                     /locus_tag="ACZPCR_06655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006907074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HIR1230592.1"
                     /translation="MSVLEIKNIEKSFGGSRVLKDISIQVEDGEIVSIIGPSGSGKST
                     LLRCAAMLETMDRGAVLYEGRKAVWNQGDGRVQYAGKEEMKEIQAMYGLVFQNFNLFP
                     HYSVLKNITDAPIHVQKRKREEAEAEARELLAKMGLSDKADMYPCQLSGGQQQRVAIA
                     RALALHPRILFFDEPTSALDPELTKEVLKVIRSLADLNIAMVIVTHEMAFAREISDRV
                     IFMADGVIVEEGKPEKVFSSENERTRAFISGISG"
     gene            complement(29990..30973)
                     /locus_tag="ACZPCR_06660"
     CDS             complement(29990..30973)
                     /locus_tag="ACZPCR_06660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007594825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HIR1230593.1"
                     /translation="MPGFTTHYIFGMKAYNDLPNNQLKRIIAKYRWLYQLGLQGPDMF
                     FYYIPVLRHRDYRNVGSYMHEHHINEFFRCSLNRLSRLQSRQQREQAAAYLAGFMNHY
                     IADYVCHPYVYGRIGYDTSNPSAVHHGKHAALENDIDAILLYKYKKKKPSEFNQTATI
                     CLNGQEMQFVSHFLASCINDAYYPITYRNNFQITPAMVHRSIWAMRVGCRTLADKSGK
                     KKGGIAIVESLFVSHPVASAKLVTDTFSDPRKCCNLDHEPWCNPWNKALASTDSFVDL
                     FHLTLNKLHNVYYYFNACLSSGIPLEEQDFHKLLMELGNYSYHSGLDVGGN"
     gene            31229..32371
                     /locus_tag="ACZPCR_06665"
     CDS             31229..32371
                     /locus_tag="ACZPCR_06665"
                     /inference="COORDINATES: protein motif:HMM:TIGR00835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HIR1230594.1"
                     /translation="MEKRGQPFEREGRAMVQWILGIVWGPWLTVLFLAAGIYFTVRFR
                     GFQITGCFLWWRETAGSLLKGGNKEKKGQFASACTALAATVGTGNIAGVAAAVAVGGP
                     GAVFWMWASAVLGMMTAYAEVYLGRKYRYKDKNGRPVCGPYAYLEKGLGMRWMGLLYA
                     AFCVLASLGMGSMVQANAVAQSADFSASIPLPVTGAVLTVLVMAVIFGGAGRISAAAV
                     SLVPVSAAFYMGLCAVILLFHAKELPGAFLLIVKDAFSAESAAGGAAGVLTGKAVRYG
                     ISRGVFSNEAGLGSLAVLHGEAEAPEEFERFGNPFAREQGMWAVFEVFFDTIVSCTMT
                     ALVLLCVGGSRTPADVGQGEAMAGSACELLPVKRTEKKYKIFPASS"
BASE COUNT         8563 a         6982 c         9434 g         7432 t
ORIGIN      
        1 ccttgattct ggagaaaccg aaaagctttg caggtattcc ctgtttagaa gcttcacgga
       61 ctcctgaatc ttatggagca ttttttcttc ccatttccca accgatttct tacagacaaa
      121 tgtatatttg tttgcacagg tttctaagtt tcacaggcat ctgccagaaa tccggtgcga
      181 aaacgagcaa tctactatga tcaggggctt tctgcccggc cagcagccac ataaagttga
      241 tgtctcgttt gcaggcgctt tctatctttc ttgaggaata aatgttttga gaataagcgt
      301 aggtcagaat cttgaacatg gtctttgggt caaccgccgg atttctgcct ttggcagagt
      361 aagcctgata cagcaggctg taatctaaat cctccaattc gtggcttagc agtcggacag
      421 aatcatcatc aggaaccaga ccttccaaat ctaatggcaa aaccagttga taaggttcgc
      481 cgaattcggt ataattctta tggtatttaa gatgtttggt catatcttat tataccatgg
      541 attgaggact cttcggagtc cgttttcttt tttaggacat aaaaatggag ctgctgctcc
      601 agtagattat tatctacttt tgcaacagcc cttttagatg aaggaatatg aaaatggcgg
      661 ctacaagact aattgcgctg catatcaata aaggaaagac ggtagcgcag tgtctggctg
      721 accgtactga ttattctgag aatgcagcaa agacggaaga tggaaaatat atcagtgcgt
      781 atgcctgtga cgcaaagacc tgtgatgaag aattcctgct ttccaaacgg cagtatgagc
      841 atatcacagg aagaacctag gcacatgatg tgattgcata tcagatccgg caatctttta
      901 agcctggaga aatcacgccg gaggaggcga acaaggttag gtatgagacg gctatgcgat
      961 tcaccaatgg aaaacacgcc tttatcgtgg caactcatgt tgatcgcgcg cacattcata
     1021 accatattat ttttaattcg actacattgg actgcaccag aaaattctgc gattttcact
     1081 tatctggtct tgcgctggca aggctcagtg atatcgtctg cctaaaacac cggttgtcgg
     1141 tcattatccg gaaaccctat ggagagcggc agaagagaac ggaatacccg gagaaaaaat
     1201 cgcagcggga tgaaatctgc gaggccattg atgcaacatt ggcaagaaaa ccaaaagact
     1261 tccgggaact gattggaatt ctgcaggagg caggatacga gtataaagac ggaaaacagc
     1321 ctgccctacg gggaaaaggt cacgccagat ttgctcgttt ccgctctctt ggcaaaggat
     1381 attcgattga agaactctgc gaagtgattg ccgggaatgc ggttcataaa agcaaatttg
     1441 cagagaaaac ccgcacaagc gcacggtttg cacaggtgca tcagagaacg gagctgtcgt
     1501 tccttattga tatccgtgcc aaaatgcagg cgggtaaagg cgcgggatat gcgcgttggg
     1561 cgaaagtctt taatctgaag cagatggcga aagctatgat gttcatggaa gagcatggaa
     1621 ttaagagcaa tgtagagctg aaagaaaagg cagaggaaat ttccgaaaat gcgatgcgct
     1681 gctggaatct gtaaaggcag atgaggcacg gatgtcggaa gtgtcagtgc tgcggaagca
     1741 tctaatcaat tatgctaaga caaaagatgt ttttgctgcg tataaggcat ccggctacaa
     1801 tcgggagttc tatgaagctc atcgggatac gctggcctta cgcagcgcag cgaaaaaggc
     1861 atttgatgcc tataagaaag agaacggctc tgataaaaag ctcccacgta ttagcgagct
     1921 gaacgcagag tatgcaatgc ttctgcaacg aaagaaaagc gcttatgcag agtatcgcaa
     1981 gaccaaatcg gaaatgcagg attggcttgt ggcgcagaag attgtgcagg aaatcctgaa
     2041 agaggacgag cagaaaaaag agcagctgca tgagcgggaa gtgcggcagg aagaagaaaa
     2101 cagacaaagt agtcgatgat ggaatgtccg gtgtagtgtg agtgtaatgc tcatgctgca
     2161 ccgggctttt ttggaaaatg atttttaata ttgttgatgt tcaactgctc ttaactcaaa
     2221 gattgtattt taacttaaaa agagttataa tacagaaaaa agagttaaga ttgcaggtga
     2281 tgacatggaa tatctcaata aagttcttgg agtcaaggtt acttatgagg atgtggagtt
     2341 taagcactta cccaatttta tagtcacaag ataccgttta cagatggtgt ctatgaatga
     2401 gaagaaggtg gttctccttt atcctaagac agaactggag cagattgaag tgctgaaaaa
     2461 gcatattgcc cggatacaga aaaatgagaa tttgcccgtt gtgctggtgc taaaagaact
     2521 tagctttcgc cagaaagaat atttgattcg tgagaagatt ccatttattg tagatggaaa
     2581 gcaaatttat ttgcccttta tggctgtgta tttgcaggaa cggtgcagtg cggaaaaaat
     2641 accacggaaa gaaatacttc catcggcgca gatgcttcta ctgcatttca tttatggagg
     2701 cgcacaggaa ctatccacaa gtcaggctgc gaaggacttg gaactgacac ctacttctat
     2761 atcaagggca tcgagacagc ttgaagaaat gggattgctg catatcagga aagccggtgt
     2821 acagaggatc atgcaatctg aggattctcc gaaaacactg ttccaaaaag caggagataa
     2881 gttgctgaat ccaataaaac gaaccgttta tattccgaaa gaattggtgg gaacagagct
     2941 gttggaaagc ggatattcgg cattggcaga gtattccatg ctgaatacac cgaatgtcag
     3001 atgttatgcg gcagaaagaa tctctcaatg gaaagatgct atgatcaata acttgcagga
     3061 ttcgcaggtg caggtggctg tagaaatgtg gagatacaat cctcgaaaat tgtctgcgcg
     3121 aaatgttgta gatgaacttt cgctggcatt ggcattgaga gaagatgcag atgaacgagt
     3181 tgaagaagca gtggaagaaa tgctgaatga actgtggaga aaaatagatg gttacaggaa
     3241 ttgacagctt tagggaatgg ttcaagggca gtgaagagca atatgccatc attggaggaa
     3301 cggcgtgtga cattctgatg acggaagaag gactggattt tcgagcaaca aaggacattg
     3361 accttgttct gattatagaa gcagttgacg cgaatttcgg aaagaaattt tggaaatatg
     3421 taaaacaggc tggatatgaa cattgcaata aaagttcggg tgtgccgcag ttttatcgtt
     3481 ttagccaccc aatctcgaat cagtatcctg cgatgattga acttttcacg cgaaagctgg
     3541 ataccattca gcttccagaa gatgcagtgc taacaccgtt accgatggac gatgatattt
     3601 caagtctgtc tgctattctt ttagacaatg attactacga atttctgaag caggggaaag
     3661 ttgtcgttga tggagtgact atcttggatg cggcatattt gattccattt aaggcaaaag
     3721 catggatgga tttggcagat cgtaaggccg caggagaaca cgttgacagc aaaaatatta
     3781 agaaacataa gaatgatgtt ttccgtctga cggagttgat tgatcccacc gcaaagatag
     3841 tagctcccaa aggagtttat gccgatattc aagagtttgt ccagcgtatg aaaaatgaaa
     3901 acgtggatat taagcaactg ggagtggttg gcagaacaaa ggagaagatt ctggaagaat
     3961 tgaaggtaat gtatgagacg gtttaaatag atatttgaac agacaagggc attgatctga
     4021 cgaatggggg tatgcttcat gccattgcag attaccagaa acgatattac aaaaatgagc
     4081 gttgacgcaa tcgtcaatgc tgccaacacg tctcttctgg gcggtggtgg tgtggacggc
     4141 tgcattcatc gtgccgccgg actggagctg cttgcagagt gcagtacgct gcatggctgc
     4201 gagacaggca gcgcaaaaat cacaaaggga taccacttgc cctgtaaata tgtgatccgt
     4261 gcagttggac cgcgttggag ggatggcaaa catcgggaac aggagcttct gcaatcttgt
     4321 tatcggacat ctttgaacct ggcaaaagaa aatggctgtc agtcggtggc ctttccgctg
     4381 atttcttccg gcatctacgg ctatccaaaa gatcaggcac tgagggttgc agtcgatacc
     4441 atcagtatgt tcctgatgga aaatgagatg atggtctaca tcgttatctt tgataagaaa
     4501 gcaaatgaga gggaacataa ttattttaat aatctgctga aaaacagcaa aacagctaaa
     4561 aaacagattg ccctgtattt ggatgaagct aaagtagagc gtatagataa aattataaag
     4621 atcttttcct cgctcagtga ttcgaaaagc ttttcaagaa atactttaat tgaagaggca
     4681 atagataaat ttataggtga atcggaacaa tttttgtatg atgaacatgg aattgacgtc
     4741 gaaagactgc tggaagagga gcgggccgaa aaatatgata cggtagtgtt ctcatcttct
     4801 ggaagaggat ttgaagagac attcttagga gagagtgaac cagcctgctg gtatccgtgt
     4861 aaagtgagcg acagcaggga aggcagtctg aaatatattg cggtttatcg cggaagactg
     4921 gtgtcagcaa tcacgcatta tgcaaaaatt aaagaattca agtatgattc agaaaagaaa
     4981 tgcaaggtat gctatttcga tggagatcca atcgaactgc cgacaaaaat caggctggga
     5041 aataaagaca gctgcttttt cattggtaca aaatatactt cgcttgaaag cctgttaaat
     5101 gcttctcagg cagacgaggt tgcttttgga taatataaat agataaggac aagttaatac
     5161 agccagcact ccccggaact tcggttccgg ggagtttttt tgactgcgga aaagcttacg
     5221 ctgctgggag agggactctt ttctgatagg acagtcattc gcgaaattta caaggccttt
     5281 tttgaaacaa atcaaaagga tttccgaaac agagtattgc tgtcacgttc acgtgatagg
     5341 ctatgctctc tatgcggaga aaggaaaggc cgtagtgaag aagacgagtg agataagcag
     5401 gattgctgga atcagcaaac gaaccttgca gttttatgat gatgaagggg tggttaaagc
     5461 ggaacgttcg gggagtaatt accgcctgta cgacgagaga gcgctggggg aactatggga
     5521 agtgatgata tataaggaag cgggaatgga actgaaagag attaaacagc tgatgcgcgc
     5581 accagaacag gaaaagaagc tgttttatca aatgtatata aaaagtctgg aagagaaaat
     5641 aaaaaggctg gaggggcaga gggaatggat ttcatttatt atgacgcatg gatttccgaa
     5701 ggtgccggag aatgaagagg gagttacata taaggagaga attgctgagc taagctgcag
     5761 ggaaacaggc ggggaagcgg gaagctgcag aaaaacagca ggggagagca gcagggagga
     5821 gaagctgaag gatctgcgga atccagctga aaaaacggtc agatattttt aaaggactga
     5881 aagaaaaggc atagctgaga ggcttctccc agctatgccg cagatatcat accatttcgc
     5941 tgaaacggaa gatggcgttc atatcgcact ccaggatatg gcagcaggca tacagaaagg
     6001 ataccgtggg gttctgtgtg cctttttcga tgcggttata ggagtagatg gagatatcaa
     6061 ttccgtgaat ttgaagtctt gcagccatat ccgtctgctt gattttcatg gatttgcgga
     6121 tttttgcaat attttttccg atattggtat catttacctg aataatgcgg tcaatgctgt
     6181 catggttttt catacgattg cacctccacg caatatttta tgtgggtttc agggaaaata
     6241 attgcacgaa aacgcaataa atgatatgct ggtactgaaa caatacggag gaggaaagct
     6301 cagtggagaa aggaaacgtt ttagtaattg gaaattcggg tgtgggaaaa tctactttga
     6361 tcaatgctgt tttaggtgag gagaaggcaa agacaggctg cggaaccaag ggcacgacag
     6421 agtatctgga aatatatgaa agtgacgaag ttccatttag gattatagat tcagttgggt
     6481 ttgaaccttc ttttattaag aaaaggcagg cagtccatgc ggtgaaaaaa tggtcaaggg
     6541 agagcgcaaa gaaagaaaat gaaaacagac cgatcaatgt aatctggttc tgcgttgacg
     6601 gaatggcgaa aaaattgttt tcagatacca taaagagtct gtccagcgcg acttccatgt
     6661 gggaatcagt tcccgtggta gtggttatca caaaatccta tgggatccca gatcgggagg
     6721 agaatgtccg gatggtttac agcgcgttcg cacagcagaa gcgttattct aaaaacctga
     6781 gaaaagtgat accggttgtc gcgtctgcct acgttctgaa tgaatctgct tatgcgccgc
     6841 cggaagggat atccgagctg atcgatatca caaatgagct tatgccggaa ggcattaaag
     6901 cggctgagaa agacatttac caatttaagc tttccagaaa gagagctctg gcgcaaggca
     6961 ttgtgagcgt gtccacaaca gctggaatta cagtgggggc ggttccagtt ccccttgccg
     7021 acgcgtttat attgtcatcg attgaagtgg cagagattaa tgctcttgca agggtgtacg
     7081 ggattaataa aaacgaagag tcaaagcatt tttttaactc tattgtcgaa gctggaacgg
     7141 tcagcgccgc cgccagaggc gctataagcg ctttaaaggg tatcccggga gtcaatttgg
     7201 cggcaggtct tgtgaacgca gtgattgccg gaagctttgt tgccgcaatt ggagaaggga
     7261 ctatttatgc gtttgagcag gtctatttag gaaagaaaac ggtaaaggat atcgactggg
     7321 tgacaaaggc cgtggaatcc agattatcta cagaattcat tgataaggtg gcatccgcgg
     7381 tcaggcagat tacagaaaac acggataaaa atgcgattgg aaaagtgatt ctggatctgt
     7441 ttggagagaa ggaaaagcag ccgggctgca atgggaaagg caggaggtag gatacacaaa
     7501 tgggaaacat acataagaac aggaaattaa tcctggcggc ggctcttgtt ctggccgtat
     7561 tagttgtcgg aagcttattc ggcccgaatg tgatgaacaa aataggaaaa gaaaacgtga
     7621 tcacgtcgtc gcagcttgaa aaggcaattg acatcagcca gctgtcgact gccgaatttg
     7681 tttacaacgg aatagcggaa aagtatgacg acgataagcc ggaaaaggtt gagtgctata
     7741 ttgcgtacca tgcggacgtc aaggttggaa ttcagatgga agacgttgag tttgagattg
     7801 atgaggaaaa caaaacggta acgccgattc tcccggaaat ttcagtcaac attgcggcgc
     7861 tggatgaaaa tgaaatcagc tatattccga agaacccgga tattcctttg aaggaaatca
     7921 ttgttttgtg caaggaagac gcagtgagag aggccaatga ttcaaaaaag ctgtatcaga
     7981 cggcagagga gaacctgaaa gctgtaatcg aagcgctggt atctccgatt ctggaacatg
     8041 ccgggtacac aataaaatgg cagagcgtca gctgaggagg attgaacatg aagagaaaga
     8101 cgaatcgggg aatcaggatg ctggctgttc ttgcagccag cggcgtctgc ctgacaggat
     8161 gtgcggagaa gaaaaaggaa gccgattttt ccggaattaa ttcagtatgt gaattagcta
     8221 cgttaaaatg ttattatcac aatgtggcga agggggagac aaaagccagc ggcctgctga
     8281 aatggttcgg taccggatat aagaaaatat ggacggagta cagcggaatc gtggagctgg
     8341 gaattgatgt aaacaaagtg tccgtttctt cgccaggcgc tgacggagta gttaaaatca
     8401 cgattccgga tgcagaaata ttgaatgtgg acctggacga agattctatg ggagaaccgc
     8461 tgacagacac tggatttctg actgaaatca caaaagagga agaaacggct gcgctggcag
     8521 aggcgcagga caacatggaa gagacggcga aaaagaacag cgcgctttta gcccaggcta
     8581 aggagagagc caaaaatctc atagagggat atgttaaaaa tgtcggagaa cagatagggg
     8641 aagaatacac aatagagtgg gaagagattg agtaaatctc aaacagaaga ataaagaatg
     8701 acagaacctc ctttcctgtc gttataagag tggataatat tcttataacg ataataggag
     8761 gtttttgatt tatgaaagga aatgtctatg ggtatgtccg cgtatccaca aaagaacaga
     8821 atgaaggcgg ccaggaagct ttccgtggcg caggatacct ttctgagatg ggttcggggc
     8881 aaataaaaag tccccctgct gtgcaggggg aagagaaaga tctgccgccg gtttgacgct
     8941 acgctgcctt ttcgcaggcg atcctctcgg aaagcctgtt gaaaacacga tcaaacagcc
     9001 agccggcagc gacggtgtac agcgcggcgg cagcgttcaa accgattctc agaatgactg
     9061 cgccggtgat tccgaacacg ccggaggcga tggaaagggc gccaaaggta ttaaacacag
     9121 tctgccatgg gtagcgggca gagtagccca cgccgattcc gccgatgagc cccagcatgg
     9181 aatgaaggtc tgccggcaga atgagataga gccccaggaa aatgagggat cctaccagat
     9241 tgaaaacgcc tctctccttt gcccgcttta ccatatcctt ttcaaaggga aggcacacgg
     9301 acatacaggc aattccggcc cacatggctc ttggaagtcc cagaagggat gcgattaaaa
     9361 gcgtggtgga aagacataag gtcagcttga tataccacct gtttctgaga gaaaacggat
     9421 taaattcctg gaacagatgg ctgaaattcc gcttgtggac gcggtgcctc tgattcttat
     9481 agaagaccgc catgcagaga agcataccga agaacagccc tgccgtccgc atgacaaagg
     9541 aatggcctgt tacgtcatag ccctgtaaaa tcaaataaga taatacaaaa gtagagtggt
     9601 tggacataag aatgttgtgg cagccgagaa acatcagaat cagaatgcag attaaattaa
     9661 tgaaaaaagc tgtaaagggg gagactgcat tggtcagcct ggggccagcc atgagaatgg
     9721 aaaaaattcc cgcaatacac agcagaccgt gggaggtgtg gatcccaaaa tcagcctggc
     9781 gcagcacaag gagagccagc agcacagcca cgccggcgat gctgttctca gagccgaata
     9841 ccatgctgaa aagcgtcaca gccgcgaagc agaacgccac caccagataa accttaaagt
     9901 tatagatcag gatatggcgc cggcgctctt ttttatcctc tgtgatgcgg attaaagtct
     9961 tggaaccggc agaattcagc tgaagttcct gataaaatgt catatgtact ctaacctcct
    10021 tagtatcagc gcaaaaaata tgcgcttcag ataagacaat aaagaagatt ttaccttttt
    10081 tggaggcaga atgcaagaaa atctttatga gcctgtctca tggattcccc attttcggca
    10141 gcagaaatat tggaacacag ccatgcagat ccagccgatg attgttccca cagccacagc
    10201 ctgcaggccc agcgcgccca gaagcaggta agtgacggtt acccggatgg gaatctggat
    10261 cagagtggcc cagagggtga tcttcaggtt tccgatcccc ctgaaatacc cctgaaaggt
    10321 atttgtgatt ccggtgagaa tataccccca ggacatggga agcaggtagg acaggccaaa
    10381 ggccagggca gacgtttcct ggggcttcag aaaaattccc agaatccagc ggctctgggt
    10441 gaagacgatg acagccgcca ggcagacgta gagttccgct atgcagagca tggttttcag
    10501 gccttttccg attctgtctc tggttccggc ccccttattc tgggcggcaa aggtggtcat
    10561 ggaggcggcc aggctgtcgc cgggagccag tatatagctg tctgcgatgg agacggcgtt
    10621 gaaggcggcc acagcgtcta cgcccagact gttgacgccg gactggacca gaaggcggcc
    10681 caggtacagc atggtctgct gaagcgccga cacagagctg taatcaatgg tctttttgag
    10741 aaatttccgc tcgatccgca tctctgacag tggaacccag agaaacctgg cccggaaaaa
    10801 aagacatccc aggagggcca gagcggacgc cgcctgagcc gacacagtgg caatggccgc
    10861 gccgcagacg cccattccca ggactcctac cagcagcaga tccaggacca cattgacagc
    10921 cgtggtaaat atcagcacgt aaaggggagc tttggaatct ccgactgccc ggagccctgc
    10981 ggccagaata ttatagagga aggtaaagaa cagtcctgcg gagacgattc tgagataatc
    11041 ggcggccaga ggggcgatct ctgccggagt ccgcgtgaag cggacaaaca gcccgcttcc
    11101 gcacacagaa accacagtga ggactgcggt gagcagaaat cccgctgtca gagaggtggc
    11161 catctccttt ctcagggact cgtagtcctt agcgccgaaa tactcggcca tcaggatgga
    11221 agaacccatg gaaattccca caatcagaaa gataaggata ttcatcacag gccctgcgga
    11281 tccgatggca gccagggcct ctttgccgtt aaattgtccg actatcacag aatctacggt
    11341 gtggtagagc tgctggaaca gattgccgaa taccagggga accgcgtagg acagcatgtg
    11401 ccctgtaata tttccctggg tcatatcccg cgtcataaaa taaaacctcc ttgagaaaaa
    11461 atgcagacat tacaataaga cgattataag ggcggaagaa caaatgatca agaagggagg
    11521 caaggcattt tcccccacag tatagaaaat acaggggaat tgtggtagaa tgatattatt
    11581 ccggactgcg cccacagggg agaacgcagg aaataaaaaa atgacaggca gtgtgaaaga
    11641 aagcagacgc tttgaaagga gtagggacga tgaaatatat ggattatata ttagagacgc
    11701 tggagaggat tgtgaacacg cccagtcctt ccggatacac gaaggaggtc atggagatca
    11761 tccgcaggga ggcggaaaac tttggttttc agacagagtt taacagaaaa ggcggcctga
    11821 ttatcacagt tccggggcag acggagcatg ttttgggatt ttccgcccat gtggacacgc
    11881 tgggcgctat ggtccgctcg gtgagatcca atggaaccct tgccctgact cagataggcg
    11941 gcatgatgat ggaggccatt gagggaagct actgccagat tctgacgaga gacggcagga
    12001 gatttacagg cacgattcag acaaaagagc cgtctgtcca cgtgtgggac gactgtaaag
    12061 agttcaagcg cacagaggag aacatggaag tccgcctgga cgaaattgtg agaacaaagg
    12121 aggacgtgga gcagctggga atcggagcgg gagatttcat cagctttgat ccgaaatttg
    12181 tgatcacaga gagcggattc gttaaatcca gacacatgga tgacaaggcg tctgcagcgg
    12241 tgctgttagg cctgttaaaa tacgtacatg acacaggaaa gaagccggaa cagacgctga
    12301 agctcctgat cagcaactac gaggaggtcg gccacggctg cagctatatt ccacaggatg
    12361 tggaggagct gattgcagtg gatatgggct gcgtgggcga cgacctgaac ggcgacgagt
    12421 accgggtgtc catctgcgcc aaggattcca gaggaccgta tgacttcgat atgacgaacc
    12481 gcctcatcgg gctggctaag gagtacggaa tcggatatat ggtggacgta ttcccccact
    12541 acggttccga cgtgtccgca gctctggcag ggggcaataa tatccgtggc gctctcatcg
    12601 gacagggcgt cagcgcttcc cacggccagg agagaactca tgtgaaaggg ctgatggaga
    12661 cctttaagct ggcggcggcc tatgcgggcc ttttaaataa ggaagaagct gagaccgttt
    12721 tcgcagattt taagggagtt caggccctgg actctgaaaa gagcgggagg taggaaatgc
    12781 aggcagtatt actggcaggc ggacttggga caaggctcag aagcgtggtc agcgaccggc
    12841 ctaagccgat ggccctgatt gagggaaggc cttttatgga gtatgtgatc cgggggctgg
    12901 cccgccatgg aattacagat atcatttttg ccgtaggcta caagggcagc atggtggagg
    12961 aacactttaa ggatggaacg gatatgggaa tccatgtttc ctacgcttat gaggaggagc
    13021 ttctgggcac agccggcgcc attaaaaacg ccgggaaatt cgtgacggag gatcagtttt
    13081 tcgttctgaa cgcagacacc ttctaccagc tggactacag ccgcctcacc gctctggccg
    13141 gggagaagaa cctggatatg gctctggtgc tccgggaggt ggaggacgtt tcccggtacg
    13201 gggcggccac gctggagaac cagatgctga caggatttaa cgaaaagctg aaagccgcag
    13261 acggggagga aaagcgtccg ggcacaatca acggaggcgt gtacctgctg aagaaaagtc
    13321 tcctggacga gattccggag ggaaaggtgt ctctggaaca ggagatgatt cccagatgga
    13381 tgaaggaagg aaagcggtta ggcggatttg tcaacgacgg atatttcatt gacataggaa
    13441 ttccggagga ttatttccgc ttccaggagg atgtgaagaa aggagtcgtg caatggtaat
    13501 tcgtgcgaaa gcgcctctgc gcgtcagctt cggcggcggc ggaacggatg tggagccatt
    13561 ctgcgtggag cagggaggag ccgtcattgg aagcactatc aataaatacg cgtactgttc
    13621 gattattccc agggaggacg accagattat cgtccactct ctggactttg atatgacggt
    13681 gaaatacaac gccagggaaa actacgtcta tgacggacgc ctggatctgg tgacagcggc
    13741 tctgaaggcc atggatatca acaaaggctg cgaggtgtat ttacagtgcg acgcgccgcc
    13801 tggatccggc cttggaacct cctccaccgt gatggtggct cttctgtccg ccatggccaa
    13861 gtggaaggga atcgagatgg acggctacgg gatggcggat ctggcctacg gcgtggaacg
    13921 cctggatctg ggaatcgccg gaggctacca ggatcagtac gcgtccacct tcggaggctt
    13981 taactttatt gaattccatg gccggaacaa cgtggtagtg aatcccctta gaattaagaa
    14041 ggacattatc catgagctgc agtacaacct gctgctgtgc tatacgggca atatccacgt
    14101 ttctgccaac attatcaagg atcaggtcaa taactacaaa aagcaggacg ccttcgacgc
    14161 catgtgcgag gtgaaggccc tggcctacgc catgaaaaac gagctgttaa ggggaaatct
    14221 ccacagcttt ggaaagcttt tagactatgg atggcagagc aagaagagga tgagcagcaa
    14281 gatcaccaat cctcagattg acgagctcta cgacgaggca aaaaaggcgg gagccctggg
    14341 cggaaagctg ttaggcgcag gcggaggagg cttccttctc atgtactgcc cttacaatgt
    14401 gaagcacaag gtggcggccc gcatggaggc agtcggcgga cagctgatgg actggaattt
    14461 cgaactgcgg ggcgtgcaga gctggtgctg cgatgaggag cgctggaagt acgacgaggt
    14521 gaaggtgcag atgccgaacc gggactatac ctttcatatt taggaggacg actgaaatat
    14581 gccggaaaaa ggaataaaaa cggtatttct ggatcgggac gggaccatga acgtggaggt
    14641 caattacctt cacaggccgg aggatttacg gctgattcca ggcgttcccc aggcggtcag
    14701 gcagctgaac gaggcgggat tctgcgtggt ggtggtgacg aaccaggccg gggtggccag
    14761 aggctactac ggggaggagg acgtaaagcg ccttcaccag tacctgaatg agcagctgaa
    14821 ggcagagggc gcccatgtgg acgcatttta ctactgtcct catcacccgg agcatggaat
    14881 cggtccgtac aagcgggagt gcagatgcag aaagcctgga atcggaatgt ttgaagaggc
    14941 ggacagggac tgccctgtgg acagagagcg gtccttcatg gtgggggaca agctgattga
    15001 cacggaggcg ggacacaggt ttggcgtcag gagtatcctg gtgggaacgg gatacggagc
    15061 tgagatacgg cgtcaggaag ctgcccgggg agattctgga gaagccgcag gctatgactg
    15121 gtatgcagag gacttaaagg cggcggcgga tctcatctgc aggctggaca gagagcagaa
    15181 cggagaggca gactgatatg gaaaagaaca ggattatgga agcgtttctg tcgcttggcc
    15241 ttctggttct ggctgtcctc tgcgtggcag ttcctttttt cgtccttttc acaggggacg
    15301 gaacctattc atggcagttt ggtgatccgg ccacaaagaa aatgatggcc gagatcgccc
    15361 ttctttttgt cctgctgtca ggaattctcc tgctgggaaa aaggcctgct gtcaggtggg
    15421 gcaaaacggc tctggtttgc cttatattct gctggggcca tgtgattttt cttcccatga
    15481 ccgtgtcggc cctgtacctg ggatatgtaa tcctggcggg acgctttgtg cggaccgttc
    15541 tgctggggca gaaggagata gaagacggat ggatggcaga ctttattctg ggagtttccg
    15601 ctgtgctgtg cgcgttctgc ctgctcagcg cctttaaaac aggaagcatt gcccagctga
    15661 ggctgttttc cgccgcttcg ggagccgccc tttatctgtg ggccgccctg tcaggcggct
    15721 ttggccgggc agccgcctgg ctgaaggaca gcgctcgaag agacggcttc cggaaagaag
    15781 gacttcaaaa agcagaattt caaaaaaaag aatttcaaat agaaggattt cagggaaaaa
    15841 acagaacgct ctgggcgctt ctgactgcct ttatcattgt gatgattctg gtacaggccg
    15901 ggcgcatgaa tatttccctg gattttgata ctctgtggta cggcgtccgc tcagagtacg
    15961 tgctggacaa tggaacggga atttacgaaa atcccggaat ggtgggtatg gcctacgtgt
    16021 acgccaaggg gctggaaacg ctggctctgc ctttaagcga tctggccagc cacagctatc
    16081 tgctggctct gaacctgtgg attgcagccg ccggattaat ggggatttac cgtctggcgg
    16141 gcctgttcat gaaccgaacg tgggctctgg cggcggcagc cctttccagc tgcattccgg
    16201 gtattatgaa catggcgatc tccgccaagc cggatgtgat tacctgggtg attcagatct
    16261 ttatggtata ttacatggcc tgctatataa agaacaggaa gtttgccctg ttagccctga
    16321 gcggaggcgc atatctgctg tctctgacca tgaaatccac ggctctggtg ttttccacgg
    16381 ctgtttttgg aatgagcggc ctgtatcttc tgggaaggcg gctcctttcc ctgagagcgc
    16441 ccctgcgcca gtggcttctt ctggctgcgc ctgcgggggc ccttacggga atctgggcca
    16501 gaaccatgat gatcacagga atgccggtga cctccgtgtt tacctctatt ttcgctgtgc
    16561 tgggctttca gatgaagtat ccctttgcca ccagcggcct tccccagaat tatgaggagg
    16621 ccagcaatct ggccgtactg cttcggaggc tcttccacat gctcctcatg cctacaggaa
    16681 aggacatggg ccatgtggtg tttgcctggg gcagccctct gatgctgttt ctcacagggg
    16741 cgtgcctggc ggctgcgctt ctcatggcgg cggcctggaa aaggcgaaga gcaggagaaa
    16801 gcggagggca gccggacaga aaacagaaca gggagtctgc taaaaaacgt ctttccctgt
    16861 acgcgcatgt ggctttctgg ccgtttctgg cagtgaacct ggtgagcctg gtgatgctgt
    16921 accagattga cggcaattat tttatgctcc tctacacagg aattataata ggaagcttaa
    16981 gccttctgca ttccctgaag caagcgggac acaggcgctt tctgcggacg gtttcctggc
    17041 ttcttgtgcc gattatggcc tttaacgtgc tgatgacggc agagtccaac tgggcgtgga
    17101 gcctgggatt ttccgagatt cagtgggcga ataagggaag ggtgaaccat gaggccctgc
    17161 agcatgaaaa gatggtgcag gcgggaaacg agcagatctg gaatatcctg gcagaggacg
    17221 agacgacgcg ggtgattgcc ttcggagacc atcctggctg tcttcagttt ccctgtgtcg
    17281 ttcagtccta caaggatatt acctccccct ggggaaatgt ggagttagtg aatacggtgg
    17341 aggcctttga ggagtatatg gcctacgccc aggcagatta cgcctatgtg gaggccggat
    17401 ttatcggcga ggggaactgg gagtggagct acggcctggt gcgccggatg attgagcggg
    17461 gaaccctgac agacctggta ttcgagcacg gcaatgtgct ggcaagagtg gatttggacg
    17521 gcgtttccag catggaaacg agagaaaatc tccgcctgtt cgatgaaaat tatatcacct
    17581 atgaaaggaa gcaaggagga aagtaacatg caggagagga aggaatacag atatctggat
    17641 cagctgacag agagatatcc atgcctttcg gctatcaggc cggagcttga gaaggcttat
    17701 gagacgctgc gggaatgcta cgcgaagggc gggaagcttc tggcagcggg aaacggcgga
    17761 agctgcgcgg attccgaaca tatcgtggga gaactgatga agggcttcgt aaagagaaga
    17821 gagctgcctg aggagatgaa ggcggcgtta aaacaggcgg atccagcgct tggagaggaa
    17881 ctgtcaggat gcctgcagca ggcccttccg gctattgccc tgacgggaca tgcgggcctt
    17941 tccactgcct ttgcaaatga tgtgaatgca gatatggcct acgcccagca ggtgatgggg
    18001 tatggaaacg agggagacgt attcttaggc attaccacct ccggaaattc tcttaacgtg
    18061 cgttacgcgg cggcagcggc cagagcgaag ggcatgaagg tgataagcct gacaggccgg
    18121 gacggcggaa aaatccggga actgtcggac atatgcctga tcgtgccgga acaggagacc
    18181 tttaaaattc aggagctgca cctgccggtg tatcacgcgc tgtgcctgat gctggaggac
    18241 tgcttctttg aatcatagga ggactttaag ccaaatgaat gaaaaactgg gaaaacgcct
    18301 gctgtacctg ggcgttccgg ctgcaggcat cgcgttctgc ctttactatc tgagcattgc
    18361 cacagaggac gtggcctaca cagactacat gagactgatt gtctcctatc ttcccgatgt
    18421 ggccaatccg gcgaaatttt tcgtgccgga cgtgctgacc cgggttccca tcacctatct
    18481 gggaaggata atcaacgtgg ccctgttcca ctacagcact gtgttcgaca tggtgctggg
    18541 ggttctcagc cacggcctcg ccgccctggc cctggcctcc tactgcaggg acaaaaaggg
    18601 ttacgccccc tggtttctgg ttatcatgct tttgatgttc agcctgaaca aatgggagat
    18661 gttaggcaat ggaagcggct gggtgtgctt tttatccatc gccggattct actggaattt
    18721 tgtcatctta gacaggacag tgtgcggcag ggagaggaaa tatgacagag tccttttaaa
    18781 ggctctgccg gcgtttctga cccttctggt ggccggccct tactgcggaa gctattctct
    18841 gattatgact atggcctact gcgccctgct ggtttccgat tacaggaaaa accgcaggat
    18901 aaataaagag tgggcagcgg atctggcctt tgtgctggga gcgctggggc tctaccttct
    18961 gagcagccac ttcgcagtct acgagtaccg gggggccacc gaggcgacct tgctttccac
    19021 cctggtatcg aacccggaat ttttcgtgaa atttattctg gaagccttcg cttccccgat
    19081 tatcggcatt gaggtagtgt cgaatgtgat aaagacgtct gcgggagtct gcctgctggg
    19141 ggcagtggtc atcttctttt acctgctggc cctctggatg aacgtgaaat acaggctgtg
    19201 ggagaggacg attctccctc ttatgctcat tctgatcggc ggagtgaacc acgcgctggt
    19261 tctctattcc agatggattt tcctccagga aaactacggc atggcttccc gctatgctat
    19321 tcagtatgag atggggatct tcggaatcct tctgaccttt gccgctgtgt ttgccctgaa
    19381 acgggagcgg agacaggttc tggccgtttt ggcaggcgga tttatctgtc ttctgctggc
    19441 aggcaatttc tataccacca gggaggaact tttaaaggcg cctctcagga agctgtctct
    19501 ggagcagacc atcgagacgg ctctggatta caggaataag acggacgagg agctgggagc
    19561 ccagcttcac accaacggag agagggcgag aaaggccctg gaaatcctgg ataaaaataa
    19621 tctgaacatc ttttatcagg aaggggcaga gtgatgaaac gctatacgaa atacgcgtat
    19681 cttgccgtgt tcgcggcatt ttatgtgttt ctgctgatgc agtttggaaa tgtatttatt
    19741 tactacgacg attacggcta cctgtcttta agctacggca cgaatattga cgtggctggg
    19801 gccgaatatt cgttttcaga gcttctggcc tttatgaaag ggcattattt taactccaat
    19861 ggccgcctgc tctatatgtt tctctactgc tttgtccata tgctgggcgg aatcagaggc
    19921 gtgcaggttt tcatggccac ggcggtgctg gcggtggctt tgctgctctt tttcactgcc
    19981 agacggatgc tggagggaag acttgaggcg gaaaaagtat cgggagacgg aacaaaagag
    20041 gagggcggag agcttcaggg ccggttaagt cccggggctt tggcggccct ggcggcgttt
    20101 ctctgcctgc tctatggaac tttgggaatc atggttcaga gaatgggaac ctactggtat
    20161 gcagccagct ttatctacgt agtgccggcc attacctttc tggtgtttgc cctgtacttt
    20221 tacagaaccg tgtttctgcc gaagggagag aaaccgggag ttctgcgcat gtgcctctgt
    20281 gccgcgctgg gatttctggc tgcctggtcc caggagcagt ggtttgtcac aacgatatcc
    20341 tttgtggtta tctgccttgg cgtcaagctg tggagagaca gaagactgga gctttacgag
    20401 attctgacgt ttctggcctg cgcggcggga ggactgatta tcatcctttc cccggctgtg
    20461 tcggccagaa tgaacagcgc aggcaacgca gagtttgcct ctttaagcct gtttggaaag
    20521 ctgggacgga atattcctct gctgatgaat ctgttcttct caggcgagaa tatccggtat
    20581 ctgatgtttt tcttccccat gatgattttc atgggatgta tggcagcggc aaaggacagg
    20641 aagcttctgc ctcttcacct gggattttca gctgtctccg ccgcagtgtt cgccggagtc
    20701 ttcctgaaac agaagcttca cgtgttcgcg ccggggactt attcagcctt aaccgccaat
    20761 cttttgctcc tttatattgc tttttgtttt gcagaagtga tattattcta tagagcagaa
    20821 aaacagatct ttggatcggc tgtctttgcg gcggcggtgc tgtccgtggg atccgcggcc
    20881 attgtgccgg aggttcccct tcggattttc tatccgtttt tatatctgtc ctggcttcta
    20941 ttcgcctatc tgtacggccg gattttactg atcgaggcca gacggattcc tttgtcagcc
    21001 gcctgcacgc tggtgttttt agccatgatc agcataccga acctgaagag catttacaca
    21061 ggctataaaa tgaattatca ggtgctcatg tacgacgacg cagtgtttaa ggagagcgcc
    21121 gaggccatcc gccagggagc ggatatcgag accatagagg tctatgagct gccggatctg
    21181 ctgtgcaaaa acgaggtagt atacgatgag aatttctcct ttatgattgc ctggatgagg
    21241 cagtattacg atctcccgga atacgtggag tttgagtaca ggcctcttag cagcatggag
    21301 gatttgagac agtaatgatt tccggcgtcc cgcttccggg attgggccgg gatattcaga
    21361 aagaatgagg aggtacgttc cagatgaaag ttgtaatatt ggcaggggga ttcggaaccc
    21421 ggatcagcga ggaaagccat ctgaagccca agcccatgat cgagattggc gagcggccta
    21481 ttttgtggca cattatgaag cactattccc agtatggatt ccatgaattc gtcatctgcc
    21541 tgggatataa gcagtatgtg gtgaaggagt tttttgccga ttacttcctc catacctccg
    21601 acgtgacctt tgacctggcc aacaaccaga tggaggtcca caacaactac gcggagccgt
    21661 ggaaggtgac gctggtggat acgggactgc acaccatgac aggaggccgc atcaagcgga
    21721 ttaaggatta tgtgggggac gagaccttcc tgctcaccta cggggacgga gtgtccgacg
    21781 tgaatctgga cgagcttttg aagttccaca gacagcacgg aaagattgcc actattacag
    21841 gcgtcaacgt gggccagcgg ttcggcgtgc tggaggtgga cgaccaggga gccatcacag
    21901 ccttcaggga gaagaacgac gacgacggca agattgtaaa cggcggcttt atggtcatgg
    21961 agccgaaggt atttgactat attgagggag attccacggt ctttgagaag gcgcctctgg
    22021 agcatctggc ggcggacaag gagctgatgg tgtaccgcca caatggtttc tggcactgca
    22081 tggataccca gcgggataag aaccatctgg aagagatgtg gcagagcggc agggcgccgt
    22141 ggaagacctg ggagaactag gagggactat gacaaatccg atttttgact tttacagggg
    22201 aaaacgcgtc ctggtaacag ggcatacggg ctttaaggga tcctggctct gcgagatcct
    22261 tctgctggca ggggcccagg ttacgggata cagcctgaat ccgccttcgg atccttctct
    22321 gtttgagctt ctgggccttt cagagcgcat ggacagccgg attggggacg tgcgggatct
    22381 ggcgcatatg aagcaggtgt ttgaggagac acagccggag atcgtgctgc atctggcggc
    22441 ccagccgatt gtcagggaat cctacaaaaa tcctgtgtat acctacgaga caaacgtgat
    22501 gggaacggtt catcttctgg agtgcgcaag actctgcccc tccgtccgtt ccttggtcaa
    22561 cgtgacgaca gacaaggtct atgagaacag agagtgggag tacggctaca gggagacgga
    22621 tcggttagac ggctacgatc cttattccaa cagcaaatcc tgttccgagc ttgtgactca
    22681 cagctatgtg aaggcctttt tcggggagga gacttccccg gctgtctccg cctgccgggc
    22741 aggaaatgtc ataggcggag gagactttgc ggcggaccgc attgtcccgg actgcatcag
    22801 ggccatgcag aagggggagg agatcgcggt gagaaatccg tattccaccc gcccctatca
    22861 gcatgtgctg gagccgctgt acctgtacct gactgtggcc atgcgccagt atgaggatcg
    22921 ctcctttgcc ggatactata acgtaggccc ggacgacgaa gactgcattg ccacgggaga
    22981 actggtggat ctgttctgcg gattctgggg cggggaggcc agatgggaaa accggtacga
    23041 cggaggcccc cacgaggcca atttcctgaa gctggactgc tcccgtgtga agaagacctt
    23101 tggctggcgg cccagatacc atgtgtccca ggcagtggag aagacggtgg agtggacgaa
    23161 ggagtggctt tcaggaggag acgtgagagc ctgcacagac cggcagatag aagaattttt
    23221 tatgaaatag caatcatcag acagagagac gaggaaatca tatgaacgaa aaagaagcac
    23281 gcagccagat cctttccctg gttgccgatt actgcagaga atttcacaat aaaaaagagg
    23341 cgttcaagga gggagaccgc atcccttacg cgtcccgcgt ctacaatgaa gacgagatgg
    23401 taaacctggt ggacagcgcc ctggagttct ggctcacctc aggccgctac acagacgaat
    23461 ttgaggcaga gttagccaga tacctgggcg tgcgttactg ctccctggta aactccggct
    23521 cctcagccaa cctgctggcc tttatggccc tgacttctcc tcttttagga gagcgcagaa
    23581 tctgcagggg agacgagatt atcacagtgg ccgcaggatt tcctaccaca gtaactccgg
    23641 ccatccagta cggagccgtg cctgtgtttg tggatgtggc catcccccag tacaacattg
    23701 atgtgacaaa gctggaggcg gcgctgtctg agaagacgaa agccgttatg ctggcccaca
    23761 cgctgggcaa cccctttgac ctgaaggcag tgaaggcgtt ctgcgacgcc cacggtctgt
    23821 ggctggtgga ggacaactgc gacgccctgg gaagccgcta tgagatagac ggggaaatga
    23881 agtttacggg aaccatcgga gatatcggaa cctccagctt ctacccgcct catcacatga
    23941 ccatgggaga gggcggagcc gtgtatacgg acaacgccct gttaaataag attatccgtt
    24001 ccttccgcga ctggggccgg gactgcgtct gcccgtccgg ctgcgacaac ctgtgcggcc
    24061 accggtttga ccgccagtac ggggagctgc ccttaggcta tgaccacaag tacgtatatt
    24121 cccatttcgg ctacaactta aaggctacgg atatgcaggc agcggtggga tgcgcccagc
    24181 tgaagaaatt cccgtccttt gtggagcgca gaaagcacaa ctttgcccgc cttcacaagg
    24241 ctctggaggg aacggaggac aggctgattc ttcctgtggc ctgcgaacac tcggatccca
    24301 gctggttcgg cttcctcatt acctgcaaag agggcgtgga tcggaacaag gtggttcagt
    24361 atgtggagga gagaggcgtt cagaccagaa tgctgtttgc cggaaatctg attaagcatc
    24421 cctgcttcga cgagatgaga aagacagggg agggctaccg cgtatccgga accctggaaa
    24481 acacagacag gattatggcg gataccttct gggtaggcgt atatccgggc atgacggacg
    24541 agatgattga ctacatggcg aaaaccatca gagaggccct gacacaggcc tgaaacgctg
    24601 gtttaagaaa gactggacaa agaggagaga ttcatggaac actgggatct gacaagggtt
    24661 cacgaggcca atttaaagct tttaaaggag attgaccgaa tctgccggaa atataaaatt
    24721 aaatatatga ttgactctgg cacgctgctg ggcgcagtcc ggcatcaggg ctttatcccc
    24781 tgggacgacg atgcggacgt gattttcacc cgccctaatt atgagaaatt tttgaaggtg
    24841 gcaggacggg agctgccgga ggggatgacg cttctgcggc cggaggatat ccggggagga
    24901 aaggtgttct atgattttac cacccgcatc atttacgaca acagccgtgt tcacgaggat
    24961 aatgagcaga tgcagtttta cgagggaaaa ctgaaccata tctgggtgga tctgttcatt
    25021 atagaccgcc ttccggagag ccggttcggg gcgtttttcg ccaaatttct tcagaaggtg
    25081 gtgtacggca tggccattgc ccacagggat cggatcgact tttccaagta cagcctggca
    25141 gacaaaatcc gggtgggaac gctgtccgca gccgggcggc tggttcccat gccggtgctg
    25201 ttccgccttc agacagccct ggcggccaag gacaggaaca aacggaccgg aaaacgctac
    25261 tgcagcaatt atcagccgga ttttctctat gtgacgctgg acgaggactg gtgcgaaaag
    25321 acggtggatc tgccctttga ggatacggtt ttgatggcgc cggagggatt tgaacacgtg
    25381 ctttccatcc tgtacggaga ctacatgact ctgcctccgg aggagaagcg ggttccggcc
    25441 cattccagca ttgaaatcca gattctggat taaggagaca cacgacaatg aagaaaattt
    25501 caattatcgt ttcagtatat aacgaggaat ctgccctgcg gcagttttac ggggagtcga
    25561 agccgatttt tgacgcgctg ccttgggatt atgagctttt gtttgtcaat gacggaagct
    25621 ccgacggttc cctggctatt ttaaaggagt ttgcggccca ggatccgaag gtgaagctgg
    25681 tgaatttctc caggaacttc ggccatgaag cggctatgat cgccggcatc gaccatttcg
    25741 acggcgacgg acttgtctgc atggacgcgg atctccagca tccgccggag tgtgtggccc
    25801 agattattga aaaattcgag gagggctatg aggtcatcaa catggtccgg acgaagaata
    25861 agtcggcggg actgatcaaa aatatcacct ccggcggctt ctacaaggta atcaacacca
    25921 tttccgatgt gaagctggag cccaacgcct ctgatttctt tgccatgacg gccaatgcgg
    25981 cggatgtttt aaagcagagc taccgggaga aggtgcgctt cctcagaggc tacgtccaga
    26041 acatcggctt taacaggacg aacatcgagt acgaggccag ggccagagtg gcgggagaga
    26101 gcaagtacag cttaaagaag ctgtttaaat tctccatcaa tacgattttg tgcttctccg
    26161 acctgccctt aaagcttgga atctattccg gcatcttcgt gggaatgatg ggcgtgcttt
    26221 tgatgattta cactatctat ggaaggatgg ttcatggggc ccccagcggc tacgctacca
    26281 ttgtggtggt gatgtgcttt atgtttgcca tgctgtttgt gattgtggga atcataggag
    26341 agtatatcgc cattatcttc acagagctga aggacaggcc gatctacatt gtgaaggaga
    26401 cagccaatat agaggaaaaa tagcaggaga gaaacatttt ccgcgcttca ctgaaagccg
    26461 ctgggagatg tttctctctt gccgtatcag aagacaggat gggaatttct taagaacctg
    26521 ctttaaatat gaagattttt tgaatttttc aaaaatgggt ataaaaaccc agggggatat
    26581 tatataatac caattacgaa ctacgaggag gtatgaagaa tgagaaaaat cctggtttta
    26641 ttagcctgcg ctgctgttct cagcggatgc gctcccaaga gcaatattgt atcccctgac
    26701 agcacagagg ggactgtggc tggacagccg gattttgatg ccaaggatga tgtggagatc
    26761 gactgggaac aggccaaggt ggatgcggag gacatcttca ccgatacgaa ggagtatccc
    26821 tacagcgtag atttccatct tctgctgcag ccggagcaga aggagatcat gttagtctgg
    26881 gtagtgaagg acgatcttcc ttctaatcag attgcaaagt attcagaggc tctcgtaaag
    26941 ggctttaacg atatggtagc cacacaggac ttctccatcg agcgttccag cgataccagc
    27001 tacggaggac tctggaagac ctacgggctc tcctatggac tggctccgga gagtacccag
    27061 gacgacgagg atacctggtt tatcagcgga agctacccgg cgggaacgga tttcaagctt
    27121 ccgtcagccg aggagattca gaaggcagtg gacagcgtag aggcggctga tgcggctgag
    27181 acagaggccc cggaggagga agcttctggg aattccgagg aagaaccagc agaggagaac
    27241 gaggccgata cagctgaata ggacaggctg ttttcagcag agaaccgtgc atttcattgg
    27301 agatgcgcgg ttttttactg tataggaaaa aagcgtcctg tgaaataaag aatgatccgc
    27361 aggaatcgca ctgcggcgtt gcggtattgt gatgctgaag cagcccgccg caggcggatt
    27421 acagacaggg actgattgta cagaaagaaa tacaaaactg cctgcaagaa agtgctttac
    27481 aaaaacactt tagtatgcta ccatagtagc acaataaaac aggaagaaac agttacggtt
    27541 acagtcacag acaggaggag cgattatgaa aaagagagta tgggcaatgg gagcggcagt
    27601 tatgatgatg ggagcactga cagcatgcgc aggcggatcc gattccaagg cggcttccac
    27661 gcaggcggag gaaagcggca cagaggcagg aaaaggagct gtttccgaga gcgaaggaga
    27721 cgatacggag acgaggcagg cagagagaac agatgagact tcagagggag gaacctttac
    27781 agttggcttt gaccaggatt tcccgcctat gggctttgtg ggagaagacg gggagtatac
    27841 aggctttgat ttggagctgg ctcaggagac tgccaagagg ctggggctta cctatgtggc
    27901 tcagcctatt gcctgggatg cgaaaaatat ggagctggag tcaggaaaca ttgactgtat
    27961 ctggaacggc tttaccatga ctggaagaga ggacgagtac acctggtctg agccgtatat
    28021 ggagaacagc caggtggtag tggtgatgga ggactctgga attgagactt tggaagatct
    28081 ggcaggaaag attgtggagg ttcaggcaga ttcttccgca gaggcggctt taaaggaaat
    28141 gcctgacctg acctccacct ttggaacgct tcagacaact cctgattata atacggcttt
    28201 catggatctg gagatgggca gcgtagacgc catcgccatg gacgtgattg tggccggata
    28261 ccagatgcag gagcgagagg gaagctttaa gattctggag gagtctctgg catcagagga
    28321 gtacgccatc ggctttaaga agggaaatac agagctgtgc gaaaaggtgc agcagaccct
    28381 ggaggagatg gcggcagacg gaaccatggc tgagatttca gagaaatggt ttggcgagga
    28441 cattaccaca gtgggaaaat aagccaggat cagagacaga aacagaacgg cgaaagaaca
    28501 aaaaaacagc aaaaatagaa cgataacagg acaggggata aaaagccatg gatttattgc
    28561 agattatgaa acagctggca ggaggaatgg gaaccagcat tgagattttt acagtgacgc
    28621 ttctggtctc ccttcctctg gggcttctta tctcctttgg aagaatgtcg aagaacccgg
    28681 ttttaagggc agcggtgaaa ttttatattt cgattatgag gggaacgccc ctgatgcttc
    28741 agctgatggt agtatatttc ggcccctact atctgttcgg aatccgggtg ggcaacggct
    28801 accgcctgtg ggcggcattt atcggatttg ccgtcaacta tgccgcttat ttcgctgaga
    28861 tttaccgcag cggcatccag tccatgccgg cgggacagta tgaggcggcg aagctgttag
    28921 gatacacaaa atatcagacc tttttccgca ttatcttccc gcaggtggta aaacggattc
    28981 tgccgtccat taccaacgag gtgatcactc tggtaaagga cacgtccctg gccttcacga
    29041 tcagcgtgat ggagatgttc acagtggcca aggccctggc ttcctcccag gtgagcatgg
    29101 ttccctttgt ggcggcggga ctgttttact atatttttaa tctgctggtg gcttccttta
    29161 tggagtatgc agagaagaag atgaattatt atcagtagcg gggagagaac atgagcgtat
    29221 tagagattaa aaatattgag aagtcctttg ggggcagccg ggtgctgaaa gacatttcca
    29281 ttcaggtgga agacggggag attgtttcca ttatcggtcc ttccggatcg ggaaagtcca
    29341 ctctgctgcg gtgcgcggcc atgctggaga ccatggatcg gggcgctgtg ctctatgaag
    29401 gcagaaaggc agtgtggaac cagggggacg gccgcgttca gtatgcggga aaggaggaaa
    29461 tgaaggagat tcaggccatg tacggcctgg tgttccagaa ttttaacctg tttccccact
    29521 attcggtgct gaaaaacatt acggacgcgc ccattcacgt gcagaagaga aagagagagg
    29581 aggctgaggc ggaagccaga gagctgctgg ctaagatggg gctttctgac aaggcggata
    29641 tgtatccctg ccagctttcc ggaggccagc agcagagagt ggcaatcgcc agagccttgg
    29701 ctttgcatcc caggattctg ttctttgacg agcccacctc agccctggat ccggagctga
    29761 caaaggaagt tttaaaggtc atccgctctc tggctgacct gaatatcgct atggtcatcg
    29821 tgactcacga gatggccttt gccagggaga tatctgaccg tgttattttc atggcagacg
    29881 gagtgattgt ggaggaggga aagccggaga aggtcttttc ctcggaaaac gaaagaacac
    29941 gggcgtttat ctccggtatt tccggctgac gaaagcctgg aggaagtctc tagttgccgc
    30001 ctacgtccag accgctgtgg taggagtaat ttccaagctc catgagaagc ttgtggaaat
    30061 cctgctcctc cagagggatt ccgctggaca ggcaggcgtt aaagtagtag tacacattgt
    30121 gcagcttgtt cagtgtcagg tggaacaggt cgacaaaaga gtctgtagaa gccagcgcct
    30181 tattccaggg attgcaccag ggctcgtgat ccaggttgca gcatttgcgg ggatcggaaa
    30241 aggtgtctgt caccagcttg gcggaggcca ccggatggct gacgaacagg gattccacaa
    30301 tcgcgatgcc gccctttttc ttgcccgact tatcagccag agtccggcat cccacccgca
    30361 tagcccagat ggaacggtgg accatagccg gagtaatctg gaaattattc cggtaggtga
    30421 tgggatagta ggcgtcgtta atacagctgg ctaggaaatg ggagacaaac tgcatttcct
    30481 ggccgttcag gcagatagtg gccgtctgat taaattcaga cggcttcttt tttttgtatt
    30541 tgtacaggag aatggcgtca atgtcatttt ccagcgccgc atgctttccg tggtggacgg
    30601 cagacggatt agaggtgtcg tacccaatgc ggccgtacac gtaggggtgg cacacatagt
    30661 ccgcaatgta atggttcata aagccggcca gataggcggc agcctgctct ctctgctgtc
    30721 tggactgcag acgagagaga cggtttaagg agcagcggaa aaattcattg atatggtgct
    30781 cgtgcatgta ggagcctacg ttcctgtaat ctctgtggcg caggacagga atatagtaga
    30841 aaaacatatc cggcccctgc agtcccagct ggtagagcca gcggtacttg gcgataatac
    30901 gtttcagctg gttgttggga agatcattgt aggccttcat accgaaaata tagtgagtgg
    30961 taaatcctgg cataaatacc gccttctttc tatgaaaaat tttaaaacga ctgtacgttg
    31021 acgttagcgt caagacacaa ggactagctt gtctttggcc tgctgacgtt aacaccagta
    31081 tagcacaatt ttcacaggag tgcaggggaa gaataaggaa atcaggaatg aaagtggagg
    31141 aaccgcgaaa ggatgtcttt tcgcgcctgt gttttgcttc aggatgcggt catggagtgg
    31201 gaaaaaaggg catacccttg actataggat ggaaaagaga ggacagccat tcgaaagaga
    31261 gggaagagcg atggtgcagt ggattctagg aatcgtgtgg ggcccctggc tgacagtttt
    31321 gtttctggcg gcgggaattt attttacagt ccgttttcgc ggatttcaga tcacagggtg
    31381 cttcctatgg tggagagaga cagctggaag cctgctgaag ggcgggaaca aggagaagaa
    31441 aggtcagttt gcctccgcct gcacggctct ggcagccaca gtggggacgg gaaatattgc
    31501 aggcgtggcg gccgcagtag ctgtgggagg gccgggagcc gtattctgga tgtgggcgtc
    31561 cgctgtcctt ggcatgatga ccgcttatgc ggaggtgtat ctgggaagaa aataccggta
    31621 caaggataag aatggaagac ctgtctgcgg tccctatgct tacctggaaa aagggctggg
    31681 gatgagatgg atgggacttc tctacgcggc cttctgtgtt ctggcctctc tggggatggg
    31741 cagtatggta caggccaacg cggtggccca gagcgcggac ttttcagcgt ccattcccct
    31801 gcctgtcaca ggggcagttc tgaccgttct tgtcatggcg gtgattttcg gaggagccgg
    31861 gcggatttct gcggccgcag tcagcctggt tcctgtatcg gccgcatttt atatgggcct
    31921 gtgtgccgtt attcttctgt ttcatgccaa agagcttcca ggggcgtttc ttcttatagt
    31981 aaaagacgct ttttcagcag agagcgcggc tgggggagct gcaggagtac tgactgggaa
    32041 agcggtgcgg tatggaattt ccagaggcgt gttttccaat gaagcggggc ttggaagcct
    32101 ggcggttctc cacggggagg ccgaggcgcc ggaggagttt gaaaggtttg gaaatccgtt
    32161 tgccagggaa caggggatgt gggctgtctt tgaagtattt tttgatacga ttgtcagctg
    32221 tactatgacg gcgttggtgc ttttgtgcgt gggaggaagc cggactccgg cagacgtggg
    32281 acagggggag gcgatggcag gaagcgcctg tgaactgctc cccgtcaaga ggacagagaa
    32341 aaaatataaa attttcccgg ccagcagcta aatgttgctg gccgcttttt atgcagcaag
    32401 gcacaacttg t
//
LOCUS       DBMDUW010000026        31337 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1101_length_31337_cov_3.153573, whole genome shotgun sequence.
ACCESSION   DBMDUW010000026 DBMDUW010000000
VERSION     DBMDUW010000026.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 31337)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 31337)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31337
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1101_length_31337_cov_3.153573"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            69..245
                     /gene="rpsU"
                     /locus_tag="ACZPCR_06670"
     CDS             69..245
                     /gene="rpsU"
                     /locus_tag="ACZPCR_06670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005603101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HIR1230595.1"
                     /translation="MSNVIVKDNESLDSALRRFKRNCAKAGIQQEIRKREHYEKPSVR
                     RKKKSEAARKRKYN"
     gene            526..798
                     /locus_tag="ACZPCR_06675"
     CDS             526..798
                     /locus_tag="ACZPCR_06675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HIR1230596.1"
                     /translation="MFDRQKRAVVSALNLPEDVMLGDMFLSFTGNRGVLIENYRSIIL
                     YTDTALRLQGKNGRLTIEGTCLTIRYYDKEQLFLSGLIRSAVFEPL"
     gene            809..2029
                     /locus_tag="ACZPCR_06680"
     CDS             809..2029
                     /locus_tag="ACZPCR_06680"
                     /inference="COORDINATES: protein motif:HMM:NF018591.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HIR1230597.1"
                     /translation="MNRFRHALTGMVRVRLTGCSPERFFNLCGQGDVEIWNISCADHE
                     YECCMTVQGFFACRPLAKKAGIRLKLLKKRGLPFFFYRNRKRKLWAAGFFSFFMILYL
                     CSLFIWDIEFQGNLRHSDQELLNFLKTEEISCGVRKGGIDCEELEGRIRSRYPDVTWV
                     SARVKGTRLYVHIKENDVVLTVPEKDQTPADLAAAENGTIVSMVVRSGIPMVRPGDTV
                     EKGQVLVSGTIPITDDGGTVVSEYTVRADADIVGRHRKVEKTKVPLWHEEKIPTGRER
                     KGIFFQIFGKTFVLLPPDFKGREWIYAAETRQAHITETFCLPFFYGTVRAEEYVSCFM
                     NYTENELSAMAEEYRRQTEAKLIEKGVQIIENNVTILDNDSACQFQLEMTVEEPFGRL
                     VPVEERKRPEGEGD"
     gene            2038..3048
                     /locus_tag="ACZPCR_06685"
     CDS             2038..3048
                     /locus_tag="ACZPCR_06685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013272736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HIR1230598.1"
                     /translation="MSVIETIIDIPMEHERNVCGQFDAYLKKIERTLHVTMIARDGAL
                     KIIGPEHAIRQAKSVFNNLIELSKRGNTITEQNVDYAISLSFTENDDKILEIDKDIIC
                     RTVTGKPVKPKTLGQKQYVDAIRKKMIVFGIGPAGTGKTYLAMAMAIQAFKNGEVGRI
                     ILTRPAIEAGERLGFLPGDLQSKIDPYLRPLYDALYQIMGAESYLHNSEKGLIEVAPL
                     AYMRGRTLDNAFIILDEAQNTTPAQMKMFLTRIGFGSKVIVTGDQSQKDLPAGAASGL
                     DTAIRVLKKLDDISFCYLTSSDVVRHPLVQKIVEAYEDYEKKSAQTQKQIQTKKRNRH
                     DD"
     gene            3038..3535
                     /gene="ybeY"
                     /locus_tag="ACZPCR_06690"
     CDS             3038..3535
                     /gene="ybeY"
                     /locus_tag="ACZPCR_06690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HIR1230599.1"
                     /translation="MTINIEYEAEKKLDLPYEEIIREVVTAALDYEKCPYEAEVNVLL
                     TDDQEIHRINQEFRGIDRATDVLSFPMGDYETPSDFERLEEVAEDYFNLETGELLLGD
                     IVISVDKVEEQAEKYGHSQARELAFLTAHSMLHLCGYDHMEEDERLVMEKKQEEILSL
                     KGYTR"
     gene            3546..5483
                     /locus_tag="ACZPCR_06695"
     CDS             3546..5483
                     /locus_tag="ACZPCR_06695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006780604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative polysaccharide biosynthesis protein"
                     /protein_id="HIR1230600.1"
                     /translation="MNGRMRRRGTGRRQPERRVITLADLQDAFDTAPPSERPSAPPFK
                     TSGHQPDRRGEPKRERTVSAAPAKKEDRRQEASAGKRPEQRKPKRQTVQEPAKTKRKK
                     TGNFVIQGTILAVAGIIVRLIGLMYRIPMTNIIGDEGMGYYSTAFNVYNIVLILSSYS
                     LPLAVSKMVSARLARGEFRNASRVLWAALVYATIAGGLACALVWHFGDFFADKVFMTP
                     FCVYALKTLAPTIWVMAYLGVLRGYFQGHGTMVPTAFSQIFEQVVNAVISVTAAGLLF
                     KVGLDSNRVFETTGYPEAFGAAGGTIGTGAGALTALLFMLFLFAVYRPVMRKRARKDR
                     KGRKESYGHISRSFALTVLPVILSSAVYNINAVLDNSIMAYGMGALGQGEEFLALWGI
                     YNNKYLLLVHVPLAMANALSSSLIPSLAAAVAKKERQEAKRKTGMAIRFSMVIAIPAA
                     VGLTVLAEPVTRLLFHSGDTASAVQMMVCGSSAIVFLSLSTVTNAILQGLSHMNIPVR
                     NAAAALILHVAALYVMLMGLHWGIYSVLYANILFAAIICLLNGLAIRKHLRYRQEIKR
                     TFLIPALAAAVMGAAAYGSYQGLLLLLKNSAAATILAVCAGGAVYGCLLLKLGGVEQS
                     ELRSMPGGTKVIALGRKFHLF"
     gene            5542..6045
                     /locus_tag="ACZPCR_06700"
     CDS             5542..6045
                     /locus_tag="ACZPCR_06700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007711737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230601.1"
                     /translation="MGQYNNRSKTLWFFAGASVFLAGMAALVLMFSGIGNREKPFSQE
                     GSQAESEKKENLAESLKGQKADREDVPEESGGGAGREIDGKGNQKEELPAGIPGEQVE
                     AQEESYCLVSENGFLLVFAKDRSSICLDTHMPLAEFPLAEQERLLDGVWFSSMMEVFH
                     YLESYTS"
     gene            6095..7405
                     /locus_tag="ACZPCR_06705"
     CDS             6095..7405
                     /locus_tag="ACZPCR_06705"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF015451.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016628 - oxidoreductase activity, acting
                     on the CH-CH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BaiN/RdsA family NAD(P)/FAD-dependent
                     oxidoreductase"
                     /protein_id="HIR1230602.1"
                     /translation="MPARKLRRQRELQRKKLDTDRRIYMSKRVIVIGGGASGMTAAIF
                     AARQGAAVTLLEHMDRVGKKILSTGNGKCNLTNRRMDASCYRSNAPGFPMEVLGRFGE
                     PETEVFFEELGIVLKDRNGYLYPASGQASSVLDALREELSRLGVTIVTECGEAEVAAP
                     GSGKGGNQEWTVLCKKGRFCSDALILAAGSKAAPSTGSDGSGYDLAKRLGHRIIRPLP
                     ALVQLRCREKFFKQISGVRADACVSIWADGERLAYDQGELQLTDYGISGIPVFQVSRF
                     ASVALSRGAQVKAEIDFYPELDRKELGRFLRERRQLLGDRNADSFLTGWFNKKLALLF
                     LRLAGISPDRNVSSLTETQLSELGRRIKQFETEIAETNPFANAQICCGGVDVREVNPH
                     TMESKKRKGLYLAGELLDVDGICGGYNLQWAWSTGALAGIHGGR"
     gene            7409..9028
                     /locus_tag="ACZPCR_06710"
     CDS             7409..9028
                     /locus_tag="ACZPCR_06710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HIR1230603.1"
                     /translation="MIRINQLKLPVDHGKQDLLKKAAKLLKIPQERIRKLTIRRQSID
                     ARKKGELLYIYAVDVQIDGSEASVAKRAKSPNILTVQEKKYQFPGPEAGAERLSDRPV
                     IIGFGPAGLFCGLMLARAGFRPVILERGADVDTRTKEVKRFWEEGTLNPESNVQFGEG
                     GAGTFSDGKLNTLVKDVSGRNTEVLRILTEAGADESILYSSKPHVGTDVLSRVVKRLR
                     EEIISLGGEVRFLTRAADLIVQDGAVTAVKTEHPERGEEMIPAMAVVLAVGHSARDTF
                     QTLFEKGISMEAKAFAVGLRIQHPQKQINLSQYGKEDPGTLGAAPYKVTRQTSNGRGV
                     YSFCMCPGGYVVNASSEPGRLAVNGMSNHAREGINANSALIVTVTPEDFPEMTAMGGI
                     TFQRRLEEAAYRAGAGRIPVQLYGDFKAGEISRQFGDVEPAFCGKTAFADLNQVLPEA
                     LCLSLKEGIEAFGGMIRGFDRRDAILAGVESRTSSPLRIGRGETMESSVKGLYPCGEG
                     AGYAGGITSAAMDGIKIAEAIAKRFQPSYRE"
     gene            9078..9932
                     /gene="proB"
                     /locus_tag="ACZPCR_06715"
     CDS             9078..9932
                     /gene="proB"
                     /locus_tag="ACZPCR_06715"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0055129 - L-proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HIR1230604.1"
                     /translation="MVKEREALKNKKRIVIKIGSSSLTHPETGDLNMRKIEKLVRIIS
                     DLRGEGREVVLVSSGAIAAGRQALGFTERPKEIAQKQAFAAVGQARLMMVYQKLFAEY
                     NQTAAQILMTKNTMINKESRFNARNTFDELLKLGTVPIVNENDTVSTYEIQFGDNDRL
                     SALVAALIGADVLMLMSDIDGMYTDDPNKNPDAEMIPLVRELTPELLAMGKDTGSSVG
                     TGGMSAKLVAAQIATGSGSDMVIANAADLDVIYEILNGEEKGTLFVENRDEQFHLSDY
                     LEKPQTGK"
     gene            9992..10219
                     /locus_tag="ACZPCR_06720"
     CDS             9992..10219
                     /locus_tag="ACZPCR_06720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013272728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HIR1230605.1"
                     /translation="MKQEKIDRINELYHKSQAVGLTEAEKEEQAALRKEYIESIRQNM
                     RGTLNSIRIKEKDGSITDLGQKYGNVGTRRH"
     gene            10257..10853
                     /locus_tag="ACZPCR_06725"
     CDS             10257..10853
                     /locus_tag="ACZPCR_06725"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HIR1230606.1"
                     /translation="MKEKAGRPAEEKEELRQKVKRLRRQLTEKERLFWDRKLAEQILF
                     LGRWKPGDCVYCYISVRNEAGTKALIQELWNRKIQVAVPRVQGKEMDFYYISKMEDLE
                     PGAMGIPEPREGCRKAAEPGAPVIVPGVAFGQDFSRLGYGGGYYDRFFEREPDHRKIG
                     ICYEFQMETALPSEDFDVKMDVIATPDRCLAREENEYA"
     gene            10846..12087
                     /locus_tag="ACZPCR_06730"
     CDS             10846..12087
                     /locus_tag="ACZPCR_06730"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008398161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0055129 - L-proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HIR1230607.1"
                     /translation="MLREIGERAKKAARKLNSLGSEEKNRGLRAAAKALLDGEAGILA
                     ANQDDVIFAAENGMSQGLIDRLELNPDRIQAMAEGLLQIAALEDPVGEVISMKPRPNG
                     LLIGQKRVPLGVVGIIYEARPNVTADAFGLCFKSGNAVILKGGKDALRSNEAIVSCLR
                     KGLSDAGLLEDAVCLITDTDRETTRQFMRLNEYVDVLIPRGGAGLIRTVVENSTIPVI
                     ETGTGNCHIYVDEGADLDMAAEIIFNAKTQRIGVCNACESLLVHKNSAPLLLPKLKER
                     LDEKNVEIRADERARAIVPQFQEASEEDWGTEYLDYILSLKLVDSLDEAIDHINTYNT
                     GHSEAIITRDYEHAQRFLNEVDAAAVYVNASTRFTDGFEFGFGGEIGISTQKLHARGP
                     MGLKELTTTKYIIYGNGQVRK"
     gene            12257..13708
                     /gene="miaB"
                     /locus_tag="ACZPCR_06735"
     CDS             12257..13708
                     /gene="miaB"
                     /locus_tag="ACZPCR_06735"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HIR1230608.1"
                     /translation="MDLKTITYTEIWNKAPSAEPERQEYFMDLCRRAVEAWKQQEQKT
                     AVTFHIETFGCQMNAHDSEKLEGILLAAGFEHTDTEEADLVLYNTCTVRENANQRVYG
                     RLGYLNSLKKKNPRMLIGLCGCMMQEDQVVEKIKKTYRFVDVIFGTHNIYKLAELLYA
                     RFETGRMVIDIWKDTDKIVEDLPSERKYPFKSGVNIMFGCNNFCSYCIVPYVRGRERS
                     RKPEDIVKEIEGMVADGVVEVMLLGQNVNSYGKNLEEPVSFAELLRRVEQIEGLERIR
                     FMTSHPKDLSDELIEVMRDSKKICRHLHLPLQSGSSRILGQMNRRYTKEKYLELAEKI
                     KREIPDISLTTDIIVGFPGETEEDFEETLDVVRKVRYDSAFTFIYSKRTGTPAAAMEN
                     QVPEDVIKNRFDRLLKEVQDISAQISGRDVHTVQKVLVEEPDSHEEGMVTGRLSNNII
                     VHFKGGTELIGTIVDVYLDESKGFYYMGTLCEH"
     gene            13721..15064
                     /locus_tag="ACZPCR_06740"
     CDS             13721..15064
                     /locus_tag="ACZPCR_06740"
                     /EC_number="2.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0071972 - peptidoglycan L,D-transpeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0018104 - peptidoglycan-protein
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HIR1230609.1"
                     /translation="MKKQHLRAAALLLAAAMTAGGGTTAFAAEGAPTGPGLEIEQGQQ
                     LPPSQPEGQGQTGSGENQPDAQAPTEGNTQTGDNGTASTAPNVTVSYNQGVGTEVTSL
                     SMNLNNYNGIGGVSYRSFVNNGGFIWWNHDGKPTGGTEASTYIEAIEIVLTGDAERDF
                     DVYYSVTSSGQGKMGWAKNGEVAGTSNLGEHLVSVEVVLVPKGQPGPASAAGRYINEL
                     TNHIRIGAEGSTMTNADGTPYTGWVSYDHERFYFKDGQSLSGWHYIDGMKFYFEPSGR
                     LVQDVDSIIGKQSSYVIKVNKTLNCSTVYAKDGDNGYIIPVKAMLTSVGDDTPIGTFK
                     TPEKYRWRLMVNDSYTQWATRITQGFLFHSITYSEPDINKLNTEGYNGLGVSRSLGCV
                     RLTCANSKWVYDNCPIGTTVVIYEDPNVASPFDKPDLIPVSDNQYWDPTDPLIQR"
     gene            15253..17898
                     /gene="mutS"
                     /locus_tag="ACZPCR_06745"
     CDS             15253..17898
                     /gene="mutS"
                     /locus_tag="ACZPCR_06745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HIR1230610.1"
                     /translation="MMAHYLETKKQYPDCILFYRLGDFYEMFFEDAKTASRELEITLT
                     GKECGLEERAPMCGVPYHAVDNYLNRLVQKGYKVAIAEQMEDPKTAKGLVKREVIRVV
                     TPGTITSSQALEESKNNYLMGIVYMDGVFGISSADISTGDYLVTEVRSERTLLDEIYK
                     FSPSEIICNEAFYMSGIDLEELKNRLHAVVTALENRFFSDDSCRKLLREHFHVNHLDG
                     LGISQYEAGTIAAGAVLQYLCETQKSTLEHLTGITPYTTGQYMMLDTSTRRNLELTET
                     LREKQKRGTLLWVLDKTKTAMGARMLRSFVEQPLISRERILDRQNAVEELNMNYISRE
                     EMAEYLNAVYDLERLIGRISYKTANPRDLIAFKSSLAMLPHIKQLLGEFQSPLLRQVD
                     EEMDTLADLTDLIERAIVEEPPISVREGGMIKDGYSEEADRLRHAKTQGKDWLADLEA
                     EEKEKTGIKTLKVKFNKVFGYYFEVTNSFKDQVPDYFIRRQTLTNAERFTTERLKELE
                     GTILGAEDKLFSLEYDLFCQVRDAVGARVETIQKTAKAIALLDVLVSLSAVATRQNYI
                     KPKINEKGVIHIKNGRHPVVEQMMRDDLFVANDTYLDNGKNRISIITGPNMAGKSTYM
                     RQTALITLMAQIGSFVPADEANIGLCDRIFTRVGASDDLASGQSTFMVEMTEVANILR
                     NATRNSLLILDEIGRGTSTFDGLSIAWAVVEYISSTKTLGAKTLFATHYHELTELEGA
                     ISGVNNYCIAVKEQGDNIVFLRKIVKGGADKSYGIQVAKLAGVPEPVISRAKELVEEL
                     SDADITARAKEIASGSRSAQPRRSVERPDEVDLRQMSIFDTVREEDIIRELMDLDISR
                     LSPVEALVTLDKFQSRLKNRWEAEK"
     gene            17910..19898
                     /gene="mutL"
                     /locus_tag="ACZPCR_06750"
     CDS             17910..19898
                     /gene="mutL"
                     /locus_tag="ACZPCR_06750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007864893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HIR1230611.1"
                     /translation="MPNIKVLDQTTINQIAAGEVVERPASVVKELLENAIDAKATAVT
                     IEIKEGGIGFIRVTDNGCGIPRDEISTAFLRHATSKIQTVEDLFTVASLGFRGEALSS
                     IASIAQVELITKTGDALSGSRYCIDGGEEKSLEEVGAPEGTTFLVRNLFYNTPARRKF
                     LKSPTTEGAHIADLVEKIALSHPEVSIRFIQNGQSRLHTSGNHNLRDIIYTVYGREIA
                     ANLLPVEMGEEPVKLSGFIGKPLIARGNRNFETYFINGRYIKSSLISKAVEDAYKPFM
                     MQHKYPFTMLNFAIDPSFLDVNVHPAKMELRFRDGEMIYKMVYHTISMALSERELIPG
                     VELGQTQKKEAPLKPVHVQRPEPFEEKRREAVQASETFKTFKASAPVFETRTSDRVLD
                     PGEGLRSQKTVIREAEPEYGRAAGQTVRQEEKERENKNQESLFQKDKIQKDENLKKPQ
                     EPQEPRQMDLFEDRLLTREARAEHRLIGQLFDTYWLVEYRDKLYIIDQHAAYEKVLYE
                     KTMATLKSREYTSQLVSPPVILTLNDSEQLLLERYMDHFTGIGFEIEPFGGREYAVRA
                     VPANLFSIAKKDLLMEMLDSLSEEAERSGADMINDRIASMSCKAAVKGNHHLSASEAE
                     TLIDELLELENPYACPHGRPTIISMSRYELEKKFKRIV"
     gene            19930..20907
                     /gene="miaA"
                     /locus_tag="ACZPCR_06755"
     CDS             19930..20907
                     /gene="miaA"
                     /locus_tag="ACZPCR_06755"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HIR1230612.1"
                     /translation="MEEKRPLIIITGPTASGKTALSIELAKQIGGEIISADSMQVYRH
                     MDIGSAKVTKEEMDGVPHHLIDVLDPPEEFNVVRFQEMAKKAMEEIYGRGNIPILAGG
                     TGFYIQALLYDIDFTETEEQSGLREELEETARTKGASALHVMLREIDPESAEAIHENN
                     VKRVIRAIEFYRQTGRKISDHNREEREKTSPYQFLYYVLDLPRPLLYSRIDERVDRMM
                     ESGLVEEVRALQAMGCTRDMVSMQGLGYKEILDYLNGELTLDEAVYILKRDTRHFAKR
                     QLTWFRRERDVRWLQPEAFGGSREEMLDAVLKDCREAFGERWLRKQPEL"
     gene            20973..22253
                     /locus_tag="ACZPCR_06760"
     CDS             20973..22253
                     /locus_tag="ACZPCR_06760"
                     /EC_number="4.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016846 - carbon-sulfur lyase activity
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0000096 - sulfur amino acid metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine gamma-lyase family protein"
                     /protein_id="HIR1230613.1"
                     /translation="MDLTSMYKTLGISEEVLKFGLEIEETLKKRFKKVDETAEFNQLK
                     VISAMQQNRLSDIHFSGTTGYGYNDLGRETLEQVYASVFHTEDALVRPQITCGTHALY
                     TALAGNLRPGDELLSPVGKPYDTLEEVIGIRNSNGSLREYGITYSQVDLLEDGSFDFD
                     GIRKAINERTKLVTIQRSKGYATRPTLSVERIGQLIAFVKSIKPDLICMVDNCYGEFV
                     ETIEPSDVGADMVVGSLIKNPGGGLAPIGGYIAGTRKCVENAAYRLGSPGLGREVGAS
                     LGVNQSLFQGLFLAPTVTAGALKGAIFAAAVYEKLGFSVVPDSTESRHDIIQAVTFGK
                     PEGVIAFCEGIQAAAPVDSFVTPEPWDMPGYDSQVIMAAGAFIQGASIELSADGPIKP
                     PYSVFFQGGLTWYHAKLGILMSLQKLKDAGIVTI"
     gene            22412..23104
                     /gene="radC"
                     /locus_tag="ACZPCR_06765"
     CDS             22412..23104
                     /gene="radC"
                     /locus_tag="ACZPCR_06765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002595577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RadC family protein"
                     /protein_id="HIR1230614.1"
                     /translation="MDYQTMKEIPGPDRPYEKCERLGAEALTDAELLSIIIRTGARGE
                     HSLALAQKILSLNEPAGILGLLHLSLPELTAVKGIGRVKGLQLLCIGELSKRIWKTLA
                     VQETKHYESPEEIAAFYMEDMRHMEQEELHLMMFNTKNMLIRESCLFRGTVNASVASS
                     REIFIEALRYHAVRLALVHNHPSGDPSPSREDIGLTEKVERAGELLGLTLLDHVIIGD
                     NSYFSFKERGML"
     gene            23108..23938
                     /gene="mreC"
                     /locus_tag="ACZPCR_06770"
     CDS             23108..23938
                     /gene="mreC"
                     /locus_tag="ACZPCR_06770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HIR1230615.1"
                     /translation="MKNSKYILAGLSFFCIVLIAVTSINNSILTPLRTGVGYVLIPFQ
                     SGVNAIGTSLYNHIRDFSTMQEAQAENEELKGRVAELTEENNRLQAEQYELERLRELY
                     ALDQDYMQYEKVAARVIAKDSGNWFQIFRINKGSNDGIKENMNVIAGGGLVGIVTDVG
                     ANYATVRSIIDDASRVSCMSMRSGDNCIVSGDLTLFQEGLLGLDHVKKEADIQEGDKI
                     VTSNISDVFLPGILVGYATELTTDSNNVTKSGQIVPVAEFDNLQEVLVITQLKDGGEE
                     "
     gene            23944..24477
                     /gene="mreD"
                     /locus_tag="ACZPCR_06775"
     CDS             23944..24477
                     /gene="mreD"
                     /locus_tag="ACZPCR_06775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HIR1230616.1"
                     /translation="MVKNSIRKIILNIILLILAFTIQICVFPQIAFLSAAPNLLLILV
                     FINGFIDGRAAGICYGLVAGLFMDLFYSGPFGFYTLFFINAGYINGVFTKYYYEDYIT
                     LPLILSITNDLAYNMYIYVFRFLIRARLDFLYYFKEIMVPEIIFTTVTTLLVYRLLLF
                     INRKLEERMQRRDSTIV"
     gene            24470..27322
                     /locus_tag="ACZPCR_06780"
     CDS             24470..27322
                     /locus_tag="ACZPCR_06780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HIR1230617.1"
                     /translation="MFRDLLEYLKELLKKVVTSRLFAISLVFVLMYGTLMARLFSLQI
                     VHGEEYQDEYISLTEKVIKTASTRGNIYDRNGNVLAYNELAYNVTVQDIGAFENSAGW
                     NFMLWELVEILNEHGETVKGDLEITADAEGNVSYTSASESARLRFLRDLYGLKSVDEL
                     DDPKGEYPSNVTAEELLREQMRIYKLDEMKDENGNLVEVPLDIAVQIVNIRYTMRFTS
                     FRKYEATTVAENISEETMADILEHTADLPGVNIEESTIRVYNDAIYFAPVIGYTGKVT
                     TDGLEELKKQSDDYELNDVAGRTGIESSMELDLKGTKGSQTIYVDNMGKILETANVVE
                     PKAGNDVWLSLDRDLQKAIYHILEKQLAGILTNVLVNQEPEEIKNVDASEIKLPIKDA
                     YFQLINNNVLSFHDFASEEASDTERQINAKFESARARIEADLKNELTSSAPAPMNALS
                     EDMQAYMQYIYTLLASDSEKLILSSEIDTKSEEYEAWKAGSLSLKEYLYYGIANNWID
                     TTRLEIENKYSSADDVYQVLVEHIFEILTDNDEFSKKIYQYLIYNDTVLGRELCLALY
                     DQGVLAYDEAQVAALRQGDANYTYSFMMQKIRNVELTPAQLALDPCTASCVVTDVHTG
                     KVLALVTYPGYDNNKINNVDYFAQVNSDLSGPLRNNATTTLKAPGSTFKPITAIAGLE
                     EGVIGLGEPVVCDGVFKEISNPLKCLGHHGPLNVVGGITNSCNVYFAELAHRMAMEGD
                     TYKADKGLETLKKYASMFGLDETSGIEIFESEPHISDMDPERSAIGQGTHAFANVQLA
                     RYVTALANRGTVFDLSLLLKETDSKGNLVQEFAPKVHEQLDIAASTWDAVFEGMRGVV
                     TRSARFQDLPVNIAGKTGTAQEVKTRGNHAFFISFAPYENPEISVAVNIPNGYNSANA
                     ALTAKSVYRYYYGYMSLDEIMSAGALNASRETINGE"
     gene            27409..28200
                     /gene="minD"
                     /locus_tag="ACZPCR_06785"
     CDS             27409..28200
                     /gene="minD"
                     /locus_tag="ACZPCR_06785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007718407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0000918 - division septum site selection
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HIR1230618.1"
                     /translation="MSEVIVITSGKGGVGKTTTSANVGTGLAILGKRVVLIDTDIGLR
                     NLDVVMGLENRIVYNLVDVVEGNCRMKQALIRDKRYPNLFLLPSAQTRDKSSVNPGQM
                     VKLVASLREEFDYILLDCPAGIEQGFKNAVAGADRAIVVTTPEVSAIRDADRIIGLLE
                     ADEMKHIDLIINRIRMDMVRRGDMMSVDDVMDILSVPVIGTIPDDEDIVISTNQGEPL
                     AGMNGFAGQAYLNICRRILGESVPFLNFDNSRNLWSKITCLLKRA"
     gene            28214..28495
                     /gene="minE"
                     /locus_tag="ACZPCR_06790"
     CDS             28214..28495
                     /gene="minE"
                     /locus_tag="ACZPCR_06790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032955 - regulation of division septum
                     assembly [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HIR1230619.1"
                     /translation="MGILRLLGRNNSGEIARKRLKLLLASDRAGCSPDILEMIRTDLL
                     HAVSRYMEVKEEDVIVQMIRTLPDGRKTPALCATILVHNIKQSKETFTA"
     gene            28492..29616
                     /locus_tag="ACZPCR_06795"
     CDS             28492..29616
                     /locus_tag="ACZPCR_06795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008955 - peptidoglycan
                     glycosyltransferase activity [Evidence IEA];
                     GO_function: GO:0015648 - lipid-linked peptidoglycan
                     transporter activity [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HIR1230620.1"
                     /translation="MIFNYSLKNYNFRIVIYMIFLSVAGILVLRSASGGDPSIVGKQI
                     LGVAVSFVCCLLISMIDYHRIFRLSTLIYAGCVALLAAVLLTGHSSGGATRWLKIFGF
                     TIQPSEFLKVGLIVVLSCYLAKNHERINKVSVLGTIVLMIALPVGLVLAQPNLSTSIV
                     ITIPLIVIIYAAGLSYKWIGGVLAAGIPAGGLFLYLAQFGIVPFLREYQARRILAKIF
                     HDSAQYADANNQQDKSIMAIGSGQLWGKGLNNAGVGSVKSGNFVAEDQTDFIFAVIGE
                     ELGFVGSMVIISVLALLVFECLLTASRAKDMGGRLVCIGMAVLIGFQGFANIAVATGI
                     FPNTGLPLPFISSGISSVLSIYAGMGIVLNIELQRKSSNN"
     gene            29631..30026
                     /gene="mgsA"
                     /locus_tag="ACZPCR_06800"
     CDS             29631..30026
                     /gene="mgsA"
                     /locus_tag="ACZPCR_06800"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006774757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006007 - glucose catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HIR1230621.1"
                     /translation="MNIGLVAHDSKKKLMQNFCIAYRGVLSRHSLYATGTTGRLIEEV
                     TNLNVYKYLPGHLGGAQQLSSQIEHDQMDLVIFLRDPSTAKSHEPNVNNVVMICDMYN
                     IPIATNVATAELLIKSLERGDMEWREMYR"
     gene            30088..31029
                     /locus_tag="ACZPCR_06805"
     CDS             30088..31029
                     /locus_tag="ACZPCR_06805"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013272703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HIR1230622.1"
                     /translation="MFGLAAALFLTGCSGNTLEEPYSFADRGSNLGVSEGSASLAPLF
                     ASDLCVIDGEPADDSTEFTGEAGAVFGITDQHVIYSKNAYKQLYPASITKVMTALIAI
                     EEGELSDTVQVTKDAVITESGASLCGIKPGDTLTMEQLLYGLLIPSGNDAANAIAVHM
                     SGSVEAFAGRMNEKARQLGATQTHFKNPSGLSDPEHYTTAYDLYLIFNEAMKLPKFRE
                     IIGADAYTASYTDAQGNAVSKTWKVGNWYQNGETETPEGLTVLGGKTGTTQAAGYCLI
                     MAEQDEAGKEYISVVLKAENRQGLYKNMTNIITKIVD"
     gene            31122..>31337
                     /locus_tag="ACZPCR_06810"
     CDS             31122..>31337
                     /locus_tag="ACZPCR_06810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="twitching motility protein PilT"
                     /protein_id="HIR1230623.1"
                     /translation="MIQIISGNKGKGKTKYLLDMANTAIKESTGSIVYLDKSSKHMYE
                     LNNRIRLINVNEYPITSSEGFIGFICGI"
BASE COUNT         8310 a         6954 c         9169 g         6904 t
ORIGIN      
        1 aaaaaatgcc caaacagttg tattaatatg cacttattac acaactgaag ggaggttagg
       61 tgtgagctat gtcaaatgta atcgttaaag ataacgaaag cttagacagc gctttacgca
      121 gattcaaaag aaactgtgca aaggctggta ttcagcagga gattcgcaag agagagcatt
      181 acgagaaacc aagcgttaga cgtaagaaga aatctgaagc tgctagaaaa cgcaaataca
      241 attaatcaag acaaaatccc tggctttaaa agccagggat tttttgtggt gcgccagtct
      301 ccaccttgcg aatgagggaa aatttttgat gatttttgtc ttgcgaacaa ggaaaacttt
      361 ttgatgattt ttgtcctatg aacgaggaaa aattttcggt gactttgctg gaacaagaaa
      421 atttttccct cgttcatttt taacagatgc tttttacggt ccaggcataa gctgcctggc
      481 ttttttcata tattgagtat gagaatgggg agaggcggcg cttgcttgtt cgacagacag
      541 aaaagagcgg ttgtgtcggc cctcaatctt ccggaagacg taatgttggg ggatatgttt
      601 ctgagcttta cgggaaacag aggcgttctg atagaaaatt acaggagtat tattctctac
      661 acagatacgg cgctgcggct tcagggaaaa aacggccgtt taacgataga gggaacatgt
      721 ctgacgatcc gctattatga caaggaacag ctttttctgt cagggctgat ccgctctgca
      781 gtattcgagc cgctttaagg aggagaacat gaaccggttc agacatgcgc ttacgggaat
      841 ggtgagggta aggcttacgg gctgttcgcc ggaacggttt ttcaacctct gcggccaggg
      901 agacgttgaa atatggaata tttcctgtgc agatcatgaa tatgaatgct gcatgacggt
      961 tcagggcttt ttcgcctgcc gccctctggc aaaaaaagct ggaattcgcc tgaaactgct
     1021 gaaaaagagg gggctgccct tcttttttta cagaaacaga aagcggaagc tgtgggctgc
     1081 cggctttttt tcttttttca tgattctgta tctctgctcg ctgtttatct gggatatcga
     1141 atttcagggg aatctgcgcc actcggacca ggaactttta aattttctga agacagagga
     1201 gatttcctgc ggagtgcgaa agggcgggat tgactgtgaa gagctggaag gcaggatccg
     1261 aagccggtat ccggacgtta cctgggtttc ggccagagtg aagggaacca ggctgtacgt
     1321 ccacattaag gaaaatgacg tggtgctgac ggttcctgaa aaggatcaaa cgcctgctga
     1381 tctggcggca gctgagaacg gaacgattgt ttccatggtc gtcagaagcg gtatccctat
     1441 ggtgcgtccg ggggatacgg tagaaaaggg gcaggtgtta gtcagcggga cgattcccat
     1501 tacggacgac ggaggaacgg tcgtatcaga gtacacagtc agagcagacg cagatattgt
     1561 gggaagacac agaaaggtgg aaaaaacgaa ggttcccctg tggcatgagg aaaagattcc
     1621 aacaggcaga gagcggaaag gaattttctt tcagatattt ggaaaaacct ttgtcctgct
     1681 gccgccggat ttcaagggga gggagtggat ttatgcggca gagacgagac aggctcatat
     1741 tacagagacc ttctgcctgc cttttttcta tgggacggtc agagcggagg aatatgtgtc
     1801 ctgttttatg aattatacag aaaacgagct ttccgccatg gcagaggaat acagaagaca
     1861 gaccgaggca aaattaatag aaaagggggt acaaattata gaaaataatg ttacaatact
     1921 agataatgat tctgcctgcc agtttcagct ggagatgacg gtggaggagc cctttggccg
     1981 cctggttcct gtggaggaaa ggaagcgtcc agagggggaa ggagactaac agcaaagatg
     2041 agcgtaatag agactataat cgacataccg atggagcacg agaggaacgt ctgcggacag
     2101 tttgacgcgt acctgaaaaa aatcgagcgc acgctccacg tgacgatgat tgccagagac
     2161 ggggcgctta aaatcattgg tccggagcac gctatccggc aggcgaaaag cgtatttaac
     2221 aacctgattg agctttccaa acgggggaat accatcacag aacagaatgt ggactatgca
     2281 atttccctgt cctttacaga aaatgacgat aaaattctgg agatagacaa agacattatc
     2341 tgccgcacag taaccggaaa gccggtgaag cccaaaactc tgggacagaa gcagtatgtg
     2401 gatgccatca gaaagaagat gatcgtattc ggcatcggcc cggctggaac gggaaagacg
     2461 tacctggcta tggccatggc cattcaggcc tttaaaaacg gggaggtggg cagaattatc
     2521 ctgacccgac ctgccattga ggcgggagag cggctgggct ttctgccggg agatctgcag
     2581 agcaaaatag acccctattt aagacctctg tacgacgcgc tgtaccagat tatgggggcg
     2641 gagagctatc tgcacaactc cgagaagggc ctgatcgagg tggcgcctct ggcctacatg
     2701 agagggcgca ccctggacaa cgcttttatt attctggatg aggcccagaa tacgacgccg
     2761 gctcagatga agatgttcct gacgcgaatc ggcttcggtt ccaaggtgat cgttacggga
     2821 gaccagtccc agaaggatct gccggcagga gcggcgtcag gacttgacac ggccatccgg
     2881 gttttgaaaa agcttgacga tatcagcttc tgctatctga ccagctcgga cgtggtgcgc
     2941 cacccgctgg tacagaagat tgtggaggcc tacgaggatt acgagaagaa gagcgctcag
     3001 acgcagaagc aaatacagac gaaaaagagg aacagacatg acgattaata ttgaatacga
     3061 ggcagagaaa aagctggatc ttccctatga ggagatcatc agagaggttg tgacggccgc
     3121 tctggattac gagaaatgtc cctatgaggc ggaagtaaat gtgcttctca cagacgatca
     3181 ggagatccac cggatcaacc aggaattccg cggcatcgac cgtgccacgg acgtgctctc
     3241 atttcctatg ggagactatg agacgccttc tgattttgag cgtctggagg aggtggcgga
     3301 ggattatttt aacctggaga caggagagct tctgctggga gacattgtta tttctgtgga
     3361 caaggtggag gaacaggcgg aaaaatacgg ccattcccag gccagagagc tggcgttttt
     3421 gacagctcac agtatgctcc acttatgtgg atatgaccac atggaagagg acgagcgtct
     3481 ggtgatggag aagaagcagg aagaaatttt aagccttaaa ggctacacca gataggcggt
     3541 tctctatgaa tggaagaatg agacgaagag ggacgggaag gcggcagccg gagcggagag
     3601 tgattactct tgcggatctt caggatgctt ttgacaccgc tcctccatca gaacgtccgt
     3661 ctgcgcctcc ttttaagact tccgggcacc agccggacag acggggagaa ccgaagagag
     3721 agcggactgt atctgcagcg ccagccaaaa aagaagacag gcggcaggag gcttctgccg
     3781 ggaagaggcc ggaacaaagg aagcctaaaa ggcagacggt acaggaaccg gcaaaaacca
     3841 aacggaaaaa gaccgggaat tttgtgattc agggaacgat ccttgccgtg gccggcatta
     3901 ttgtgcggct gattgggctg atgtaccgga tccccatgac aaatatcatc ggggacgagg
     3961 gcatgggata ctattccact gcctttaatg tgtacaacat tgtcctgatt ctctcctcct
     4021 acagccttcc tctggccgtc tccaagatgg tttcggcaag gctggccaga ggagagttca
     4081 gaaatgcctc ccgggtgctc tgggcggctc tggtgtacgc taccatagcc ggagggctgg
     4141 cctgcgctct ggtctggcat ttcggcgatt tttttgcgga caaggtgttt atgactccgt
     4201 tctgcgtata cgccttaaag acgttagccc ccaccatctg ggtgatggcc tatctgggcg
     4261 tgctgagggg ctatttccag ggccacggaa cgatggttcc caccgccttt tcccagattt
     4321 ttgagcaggt agtgaacgcg gtaatcagcg tgacagcggc aggccttttg tttaaggtgg
     4381 gactggattc caaccgcgtt ttcgagacca caggatatcc ggaggccttc ggagcagccg
     4441 gaggcaccat cggaacagga gcgggcgctc tgactgcgct cctcttcatg ctgtttttat
     4501 ttgctgtcta ccgtccggtg atgagaaagc gcgccagaaa ggacagaaag ggaaggaaag
     4561 agtcctacgg ccatatttcc agatccttcg ccctgacggt tctgccggtt attttaagct
     4621 ctgccgtcta taacatcaac gcagttctgg acaacagcat tatggcttat ggaatgggcg
     4681 ctctgggcca gggagaggaa ttcctggcgc tctggggcat ttacaacaat aaatatctgc
     4741 ttctggttca tgtgccgtta gccatggcca acgccctgtc ctcctctctg attccgtccc
     4801 tggcggcggc tgtggcgaaa aaggagaggc aggaggcaaa aagaaaaaca gggatggcga
     4861 tccggttttc catggtaatt gccattccgg ccgctgtggg actgacggtt ctggcggaac
     4921 cggtgactcg tcttctcttc cacagcgggg atacggcgtc ggcggtccag atgatggtct
     4981 gcggctcctc agccattgtg tttttatctc tgtccacagt gacgaacgcg attttacagg
     5041 ggctgagcca catgaatatt ccggtccgga acgcggcagc agccctgatt cttcatgtgg
     5101 cggctctgta cgtgatgctc atgggacttc actggggaat ttacagcgtg ctgtacgcca
     5161 atattctgtt tgcggccatt atctgcctgt taaatgggct ggcgattcga aagcatctgc
     5221 gatacagaca ggagataaag agaaccttcc tgatccctgc tctggcggcg gcagtgatgg
     5281 gagcggcagc ctacggaagc taccagggcc tgcttctgct ccttaaaaac agcgcggcag
     5341 ccacgattct ggcagtgtgc gccggagggg ctgtctacgg ctgtctgctt ttaaagcttg
     5401 gcggcgtgga acagtcagag cttcgctcca tgccgggcgg cacaaaggtc attgcccttg
     5461 gacgaaaatt ccatcttttt taaaaatgtg tttaaaaagt tccctcctga cggatactac
     5521 cggtaaggag ggaatttttt catgggacaa tataacaaca ggagcaaaac gctttggttt
     5581 tttgcaggcg catctgtttt tcttgcaggc atggcggcgc tggttctgat gttttcagga
     5641 atcggaaaca gggagaagcc cttttcacag gaaggttccc aggcggagag cgaaaagaaa
     5701 gagaacctgg cagagagtct aaaagggcag aaggcggaca gagaagacgt tcctgaagaa
     5761 agcggcggag gggcaggacg ggaaatagat ggaaaaggga atcagaaaga ggagcttccg
     5821 gctggaattc caggagagca ggtggaggcc caggaggaga gctactgcct tgtatcggaa
     5881 aatggctttt tgctcgtctt tgcaaaggac agaagctcta tctgcctgga tacccacatg
     5941 ccgctggcgg aatttcctct tgcagagcag gaacggctcc tggacggcgt gtggttttct
     6001 tccatgatgg aggtatttca ctatctggag tcctacacca gctaaatttt aaattgcact
     6061 tttttttctg ttcatgtata ctagcgtcag tgatatgccc gcgcgaaagc tgcgccggca
     6121 gagagaatta cagcgtaaaa agctggatac agacaggaga atttacatgt caaaacgtgt
     6181 gattgtgata ggaggcggag cttccggcat gacggcggca atttttgcag ccagacaggg
     6241 cgccgcggtg acgcttttgg agcatatgga ccgggtgggg aagaaaattt tatccacagg
     6301 caatggaaag tgcaatctga cgaaccggcg tatggacgca tcgtgctacc gaagcaatgc
     6361 gcctgggttt cccatggagg tcttaggccg gtttggagag ccggagacag aggtcttttt
     6421 tgaggaactg gggattgttc taaaagacag gaatggttat ctttacccgg cttccggcca
     6481 ggcgtcctca gttctggacg ctcttcggga ggaattatcc aggctgggag taaccatagt
     6541 gacagaatgc ggcgaagcag aggtggctgc gcctggctct ggaaaagggg gaaatcagga
     6601 gtggacggtt ctgtgcaaaa aagggcgttt ttgctcggac gctctgatcc tggcagcagg
     6661 ttccaaggcc gccccttcca caggctccga tggaagcggc tacgatttgg cgaaaaggct
     6721 gggacacagg attatccgtc cccttcccgc tctggtgcag ctgcggtgcc gggaaaagtt
     6781 ttttaagcag atttccggcg tcagggcaga cgcctgtgtc agcatctggg cagatgggga
     6841 gaggctggct tacgatcagg gagagttgca gctgacggac tacggcattt ccggcattcc
     6901 tgtgtttcag gtgagccgtt ttgcctctgt ggccctgtcc cgtggagcgc aggtgaaggc
     6961 tgagattgat ttttacccag agcttgaccg gaaggagctg ggacgtttcc tcagggagcg
     7021 cagacagctg cttggagatc ggaacgcaga cagcttttta accggatggt ttaataagaa
     7081 actggctctt ttgttcctcc gcctggcggg aatctctccg gacaggaacg tatccagcct
     7141 gacggagacg cagctgtctg agctgggcag gcggatcaag cagtttgaga cggaaattgc
     7201 ggagacaaat ccgtttgcga acgcccagat ctgctgcggc ggcgtggatg tgagagaggt
     7261 gaatcctcac acaatggaat caaaaaagag aaagggcctt tatctggctg gagagctgtt
     7321 ggatgtggac ggcatctgcg gaggctacaa cctgcagtgg gcctggagca ctggagccct
     7381 ggcaggcatt catggaggaa gatagagcat gatacgaatc aaccagctga agcttcctgt
     7441 ggatcacggg aagcaggatt tattgaaaaa agcggcgaag cttttaaaaa ttccccagga
     7501 gagaatcagg aagctgacca tcaggcgcca gtccatagac gccagaaaaa agggagagct
     7561 gctgtacata tatgcggtgg acgttcagat agacggaagc gaggcttctg tggcaaaacg
     7621 ggcgaaaagc cccaatattc tcaccgtgca ggaaaagaaa taccagtttc ccggacctga
     7681 ggccggtgca gagcgccttt ctgacaggcc tgtgatcata ggctttggtc ctgcgggact
     7741 tttctgcggc ctgatgcttg cgagggcagg ctttcggcct gtcattttag agcggggcgc
     7801 agatgtggac acgagaacaa aagaggtgaa acggttctgg gaggagggaa ctttaaatcc
     7861 tgaatccaac gtccagtttg gggaaggagg agccggaacc ttttccgacg gaaagctcaa
     7921 tactctggtc aaggacgttt ccggcagaaa tacagaggtg ctgaggatcc tgacagaggc
     7981 gggggccgac gagtccattc tctattccag caagccccac gtggggacgg acgttttaag
     8041 ccgcgtcgtt aagcgcctga gagaggagat catttctctg ggaggagaag tgcgctttct
     8101 caccagggca gcagatctga ttgttcagga cggagcggta acggctgtga agacagaaca
     8161 cccggagcgg ggggaggaga tgattcccgc gatggctgtg gttctggctg tggggcacag
     8221 cgccagggac accttccaaa ctctgtttga gaaggggatt tccatggaag ccaaggcctt
     8281 tgcagtgggc cttcgaatcc agcatcccca gaagcagatc aacctgtccc agtacgggaa
     8341 ggaggatccg ggaacgcttg gggccgctcc ctacaaggtg acccggcaga cgtccaacgg
     8401 cagaggcgtc tactccttct gtatgtgtcc cggcggctat gtggtcaacg cctcctcgga
     8461 gccgggacgt ctggcagtaa acggtatgag caaccacgcc agagagggaa taaacgccaa
     8521 cagcgcctta attgtaacgg tgacgccgga ggattttccg gaaatgacag ccatgggagg
     8581 cattaccttc cagagacgtc tggaggaggc ggcttaccgg gcgggagccg gcaggattcc
     8641 cgtccagctg tacggagatt tcaaagccgg agaaataagc cggcagtttg gggacgtgga
     8701 accggctttc tgcgggaaga cggcctttgc cgacttaaac caggtgcttc cggaagctct
     8761 ctgtctctca ctgaaagagg gaattgaggc tttcggaggc atgatccggg gctttgaccg
     8821 ccgcgacgcc attctggcag gggtggagag ccgtacctcc tcgcctcttc gcattggcag
     8881 gggagaaacc atggagagca gcgtgaaggg actctatcca tgcggagagg gagccgggta
     8941 cgcaggggga atcacctccg ccgccatgga cggaattaag atcgcagagg ccatcgcaaa
     9001 acggtttcag ccgtcttaca gggagtaagc agacgaggag aagcagagag gggaaagcag
     9061 agagaggaag cgcagatatg gtaaaagaga gagaagcatt aaaaaataag aaacgaatcg
     9121 tcatcaagat aggttcctca tccttaaccc atccggagac gggggatctg aacatgagaa
     9181 agatcgagaa gctggtccgc attatcagcg atctgcgggg agagggacgg gaagtggttc
     9241 tggtatcctc aggcgcgatt gcggcaggcc gtcaggcgct gggctttacg gaacggccaa
     9301 aggagattgc ccagaagcag gcctttgcgg ctgtaggcca ggccaggctg atgatggtgt
     9361 accagaagct gtttgccgaa tataatcaga cggcggctca gattcttatg accaagaaca
     9421 ccatgatcaa caaggagtca agatttaacg ccagaaatac ctttgacgag cttttaaagc
     9481 tgggaacggt gcctattgtc aatgaaaacg acacggtgtc cacctatgag atccagttcg
     9541 gagacaatga ccgcctgtcg gccctggtag ccgctctcat cggcgcggac gtgctgatgc
     9601 tgatgtctga cattgacggt atgtatacgg atgatccaaa taaaaatcca gacgccgaga
     9661 tgattcctct ggtgcgggag ctgacgccgg agcttttagc catgggcaag gacacaggca
     9721 gcagcgtggg aacgggaggc atgtcggcca agctggtggc agcccagatt gccacgggaa
     9781 gcggatccga tatggttatc gccaatgctg ctgacttaga cgtgatctat gagattctaa
     9841 acggagaaga aaaaggtacc ttatttgtag agaaccgtga tgaacagttc catctgagcg
     9901 actacctgga aaagccgcag acaggaaaat agagaaaaaa cagaaaatag agaaaaatta
     9961 gaaaacagag aaaatcagga ggacagatac tgtgaaacag gaaaagatag acagaattaa
    10021 cgagctttac cataaaagcc aggccgtagg gctgacagag gcggagaaag aggagcaggc
    10081 tgctttaaga aaggaatata ttgagtccat ccgccagaat atgcggggaa ctttaaacag
    10141 catccggatt aaagaaaagg acggaagcat tacggatctg ggacagaagt acggaaacgt
    10201 gggaacccgc agacattagg gcgcctgaac cgtcaggaag gcgcagggag gcggatatga
    10261 aagaaaaagc tggaaggccg gcagaggaga aggaagagct gagacagaaa gtaaagagac
    10321 tgcggagaca gctgacggag aaggaacgcc ttttctggga ccgaaagctg gcagaacaga
    10381 ttctttttct gggcagatgg aagccgggag actgcgttta ctgctacata agcgtcagaa
    10441 acgaggcggg gaccaaagcg ctcattcagg agctctggaa caggaagatt caggtggctg
    10501 ttccgagagt ccaggggaaa gagatggatt tttactatat ttccaaaatg gaggatctgg
    10561 aacctggagc catgggaatc ccggagccga gagaaggatg cagaaaggcc gcagagccgg
    10621 gcgcgcctgt cattgtgccg ggagtggcct ttgggcagga tttttccagg cttggctacg
    10681 gaggcggtta ttacgaccgc ttttttgagc gggagccgga tcaccggaag atagggatat
    10741 gctatgaatt tcagatggaa acagcgcttc cgtcagagga ttttgatgta aaaatggatg
    10801 tgattgccac accggacaga tgcctggcaa gagaggagaa cgaatatgct tagggaaatt
    10861 ggagagagag caaaaaaagc ggccagaaag cttaacagcc tgggctctga ggagaagaac
    10921 cgggggctgc gggcagcggc caaggctctg cttgacggag aggccgggat cctggcggcc
    10981 aaccaggacg atgtgatttt tgccgcagaa aacggtatga gccagggcct tattgaccgc
    11041 ctggaattaa atccggacag aattcaggcc atggcagagg ggcttttgca gatcgctgct
    11101 ttagaggatc cggtgggaga ggtgatttcc atgaagcccc gtccaaacgg ccttttaatc
    11161 ggtcagaaga gagttccctt aggcgtggtt ggaatcatct acgaggccag gccaaacgta
    11221 accgccgatg cctttgggct ctgctttaaa tcaggcaatg ccgtcatttt aaagggagga
    11281 aaggacgccc tgcgatccaa tgaagccatc gtatcatgcc tgagaaaggg cctttcagac
    11341 gcaggtcttt tagaggatgc cgtctgcctg atcaccgata cggaccggga gaccacaaga
    11401 cagtttatgc gccttaacga gtatgtggat gtgctgattc cgagaggagg agccggactc
    11461 ataagaactg tggtggagaa cagtaccatt ccggtgattg agacagggac gggaaactgt
    11521 catatttatg tggatgaggg cgcggatttg gatatggctg cggagattat ttttaatgcg
    11581 aaaacccagc ggatcggagt ctgcaatgcc tgcgaatccc tgctggtcca caaaaattcg
    11641 gcgcccctgc tgcttccaaa actgaaagag cggctggacg aaaaaaacgt ggagatcagg
    11701 gcggatgaaa gggccagggc cattgtgccg cagtttcagg aggcgtcaga ggaggactgg
    11761 ggaaccgagt atctggatta cattctctct ctgaagctgg tggattccct ggatgaagcc
    11821 atcgaccata ttaataccta taataccgga cactcggagg ccattattac aagagattac
    11881 gaacatgccc agaggttctt aaacgaggtg gacgcagcgg ctgtctatgt gaacgcctcc
    11941 acccgcttta cagacggctt cgagttcggc tttggagggg agataggaat cagcacccag
    12001 aagcttcacg ccagaggccc catgggactc aaggaactga caacgacgaa atatatcatc
    12061 tatggaaacg gtcaggtgag aaagtaattt gttaaaattc tgtaagaaat taacaggcgt
    12121 tttactattt ccattaacag gcatttatgc tataatctgt agatgtcagc cgcctgcagg
    12181 gcggttttca cggaaaaggg aagtaagctt aacggataac gtcagcgcgc gctgacgctc
    12241 agaaaggacc tgatcaatgg atttaaagac tattacatat acagaaatct ggaacaaagc
    12301 cccgtctgcc gagcctgaga ggcaggaata ctttatggat ctgtgccgcc gggcggtgga
    12361 ggcctggaag cagcaggagc agaagacggc ggtgaccttc cacattgaaa cgtttggatg
    12421 ccagatgaac gcccatgact cggaaaagct ggagggcatt ctcctggcag ccggttttga
    12481 acatacggat acagaggagg ccgatctggt gctctacaac acctgcacag tcagggagaa
    12541 cgccaatcag agagtgtacg gccgtctggg ctatttaaac agcctgaaga agaaaaatcc
    12601 ccggatgctc atcggcctgt gcggctgcat gatgcaggag gatcaggtgg tagagaagat
    12661 caagaagacc taccgctttg tggatgttat tttcggaacc cacaatattt acaagctggc
    12721 agagctttta tatgccagat ttgagacggg caggatggtg attgacatct ggaaggatac
    12781 ggataaaatc gtggaggatc tgcccagcga gagaaaatat ccttttaaat caggcgtcaa
    12841 tattatgttc ggctgcaata acttctgcag ctactgcatc gtaccctatg tgcggggaag
    12901 agagaggagc agaaagccgg aggacattgt aaaggagatt gagggaatgg ttgcggacgg
    12961 cgtggtggag gtcatgctgc ttggacagaa cgtcaactcc tacggaaaga atctggagga
    13021 accggtttcc tttgcagagc ttttaaggag agtcgagcag attgaagggc tggagcgcat
    13081 ccgctttatg acctctcatc caaaggatct gtcggacgag ctgattgagg tcatgcggga
    13141 ttccaaaaag atctgccgcc atctccacct tccgcttcag tcgggaagca gccggattct
    13201 ggggcagatg aaccgccgct atacgaagga aaagtatctg gagctggcgg agaagatcaa
    13261 gcgtgagatt ccggatattt ctctgacgac ggatattatc gtaggatttc cgggagagac
    13321 ggaggaggac tttgaggaga ctctggatgt ggtgagaaaa gtacgctacg acagcgcctt
    13381 tacctttatc tattccaaga ggaccggcac tccggcggca gcgatggaga accaggttcc
    13441 ggaggacgtg attaagaacc gctttgaccg cctgttaaaa gaggtgcagg atatttctgc
    13501 acaaatcagc ggacgggacg ttcacacggt tcagaaggta ttagtggagg aaccggacag
    13561 ccacgaagag ggcatggtga caggccgtct ttccaacaat attatcgttc atttcaaggg
    13621 cggaacggaa ctgattggaa cgattgtgga cgtgtatctg gatgaatcaa aaggatttta
    13681 ttatatggga acattatgtg agcattagga gggcatactt atgaaaaagc agcacttaag
    13741 ggcagcggcg cttcttttgg cagcagccat gacggcagga ggaggaacca ctgcgtttgc
    13801 ggcggagggc gcgcctacag gcccaggact ggagatagaa cagggacagc agcttccgcc
    13861 ttcccagcct gagggacagg gacagacagg aagcggagag aatcagccgg acgcccaggc
    13921 tccgacagag ggaaataccc agacagggga caatggaacg gcttccactg ctcccaacgt
    13981 gaccgtatcc tataatcagg gcgttggcac cgaggtgaca agcctttcca tgaatctgaa
    14041 caattacaat ggaatcggag gcgtttccta ccgttccttc gtcaacaacg gcggttttat
    14101 ctggtggaac cacgatggaa agcctacagg aggaaccgag gcgtccacct atatcgaggc
    14161 cattgagatt gtgcttacag gagatgcgga gagggacttt gacgtatact attccgttac
    14221 ctccagcggc cagggcaaga tgggctgggc aaagaacgga gaggtagcgg gaacgtctaa
    14281 tttaggcgag cacctggtga gcgtggaggt ggtgctcgtt ccgaagggac agccgggacc
    14341 agcctcagcg gcaggacgct atatcaatga gttgacgaac catatccgga ttggggcaga
    14401 gggaagcacc atgacgaatg cagacggaac gccgtataca ggatgggttt cctatgacca
    14461 tgagagattt tattttaagg atggacagtc tctctccggc tggcattata tcgacggcat
    14521 gaagttctac ttcgagccat ccggccgtct ggttcaggac gtggacagca tcattggaaa
    14581 gcagagcagc tatgtgatca aggtaaataa gaccttaaac tgctctaccg tctacgccaa
    14641 ggatggagac aacggctata tcattccggt caaggccatg cttacctcag tgggagacga
    14701 tacgcctatc ggaaccttta agacgcctga gaagtacaga tggagactga tggtgaacga
    14761 ttcctacacc cagtgggcga ccagaatcac acaaggcttc ttattccact ccatcaccta
    14821 ctcagagccg gatattaaca agctgaacac agaaggctac aacggcctcg gcgtttccag
    14881 atctttaggc tgcgtgcgct taacctgtgc aaattccaaa tgggtatacg ataactgccc
    14941 gattggaact acggtagtca tttatgagga tccaaatgtg gcttctccgt ttgacaagcc
    15001 ggatttaatt cctgtttctg ataatcagta ctgggatccg accgatccgc tgattcagag
    15061 gtagtcgaag cttcatctgc caggatgaaa aagaaaagat aaaaaagagt tcccttgctg
    15121 ttctctgtga taaaaaggct gccgcccggc ttcccatatt ttgggggccg ggcagcagtc
    15181 gttcttttgc agaggagggg aaattcatac aatacataga agagaggaca gactgtggca
    15241 caattatcac ctatgatggc tcattatctg gagacaaaaa agcagtaccc ggactgcatc
    15301 cttttttaca ggctgggaga tttttacgag atgttttttg aggatgcaaa aactgcgtcc
    15361 agagagcttg aaatcaccct gacgggaaag gagtgcgggc tggaggaacg ggctcccatg
    15421 tgcggagttc cctaccatgc ggtagacaac tatctgaatc gactggtaca gaaaggctat
    15481 aaggttgcga ttgccgagca gatggaggat ccgaagacag ccaagggcct ggtgaagcgg
    15541 gaggttatcc gcgtggttac gccgggaacc atcaccagct cccaggctct ggaggaatct
    15601 aaaaataatt atctgatggg cattgtttac atggatggag tgttcggcat ttcctccgca
    15661 gatatcagta cgggagatta cctggtgacg gaggtgcggt cagagagaac gctgttagac
    15721 gaaatctata aattttctcc gtctgagatt atctgcaacg aggccttcta catgtccgga
    15781 atcgatctgg aggagctgaa aaaccgtctt catgcggtgg tgactgctct ggaaaaccgc
    15841 tttttttccg acgattcctg ccgaaagctt ctgcgggagc atttccatgt gaatcatctg
    15901 gacggactgg gaatttccca gtatgaggcg ggaaccattg cggccggggc ggtgcttcag
    15961 tatctctgcg aaactcagaa aagcaccctg gagcatctga cgggaatcac tccctacact
    16021 acaggccagt acatgatgtt agacacctcc accagaagaa atctggagct gacggagact
    16081 ctcagggaaa aacagaagag aggaaccctt ctgtgggtgc ttgacaagac gaagactgcc
    16141 atgggagcca ggatgctgcg ctcctttgtg gagcagccgc tgatttccag agagcggatt
    16201 ctggatcgcc agaacgcggt ggaggagctg aatatgaact atatttccag ggaggagatg
    16261 gcggagtatt taaacgctgt ctacgatctg gagcggctta tcggacgaat cagctacaag
    16321 acggcgaatc ccagagatct gattgccttt aagagctctt tagccatgct tcctcacatc
    16381 aagcagcttc tgggagaatt ccagagcccg cttctccggc aggtggacga ggagatggat
    16441 acgctggcgg atctgacgga tttaatcgag cgggccattg tggaagaacc gccgatttct
    16501 gtcagagaag gaggcatgat taaggacggc tacagcgagg aggcagaccg tctgcgccat
    16561 gcgaaaaccc agggaaagga ctggctggcg gatctggagg cagaggagaa ggaaaagact
    16621 ggaatcaaga ccttgaaggt gaagttcaac aaggtgttcg gctactattt cgaggtgacc
    16681 aactccttca aggatcaggt tccggactat tttatcagac gccagactct gaccaatgcg
    16741 gagcgtttta ccacagagcg tttaaaggag ctggaaggta cgattctggg ggcggaggac
    16801 aagctgtttt ccctggagta tgatctgttc tgccaggtga gagacgccgt gggggcgaga
    16861 gtggaaacca tccagaagac ggccaaggcc atcgccctgt tagacgtgct ggtgtctctg
    16921 tcggcggtgg cgacgcgcca gaattacata aagccgaaaa tcaacgagaa gggtgtcatc
    16981 cacattaaaa acggccgcca tccggtggtg gagcagatga tgcgggacga tctgtttgtg
    17041 gctaacgata cttatctgga taatgggaag aaccgtattt cgattattac aggccccaat
    17101 atggcgggta agtccactta catgaggcag acggccctga ttaccctgat ggcccagata
    17161 ggaagctttg tgccggcgga cgaggccaat atcggcctgt gcgaccggat tttcacgagg
    17221 gtgggagctt ccgacgatct ggcttccgga cagagcacct ttatggtgga gatgacggag
    17281 gtggccaata ttcttcggaa tgccaccaga aacagccttc tgattctcga tgaaattgga
    17341 aggggaacca gcacctttga cggcctttcc atcgcctggg cggtagtgga atacatcagc
    17401 agcacgaaga ctctgggcgc gaaaacgctg tttgccactc attaccacga gctgacggag
    17461 ctggagggag ctatcagtgg agtgaacaat tactgcatcg ctgtaaaaga gcagggagac
    17521 aacatcgtat tcctgagaaa gattgtaaaa ggcggggctg ataaaagcta cggaatccag
    17581 gtggccaagc tggcgggagt gccggagccg gttatcagcc gggccaagga gctggtggag
    17641 gagctttcag acgcggatat tacggcccgg gccaaggaga ttgcttccgg cagcagaagc
    17701 gcccagccca gacgcagcgt agaacgtccg gacgaggtag atctgcggca gatgtcgatt
    17761 tttgataccg tccgcgagga ggatattatc cgggaactga tggatttgga tatcagcaga
    17821 ctgtctccgg tggaggctct ggtaactctc gataaattcc agtcaaggct taaaaaccgc
    17881 tgggaggcag agaaatagga ggtgttttgg tgccaaatat taaggtgctt gatcagacga
    17941 ccattaacca gattgcagcg ggagaggtgg ttgaacggcc cgcttccgtg gtaaaggagc
    18001 ttttggagaa cgccatcgac gcgaaagcga cggcagtgac catcgagatt aaggaaggcg
    18061 gaatcgggtt catccgggtg acggacaatg ggtgcggaat ccccagagac gagatttcca
    18121 ctgcgtttct acgccatgcc accagcaaga ttcagacggt ggaggatctg tttacggtgg
    18181 cctctctggg ctttcgcggc gaggctctct ccagcatcgc ctccattgcc caggtggagc
    18241 tgattaccaa gacaggagac gccttatccg gttccaggta ctgcattgac ggaggagagg
    18301 aaaaaagtct ggaggaggtg ggcgctccgg aggggacgac ctttctggta cggaatctct
    18361 tttacaatac gcctgccaga agaaaatttt taaaatcccc gacgacagaa ggagcccaca
    18421 tcgccgacct ggtggagaaa attgccctgt cccatccaga ggtatcgatc cgcttcatcc
    18481 agaacgggca gagccggctt cacacgtcgg gaaaccacaa tctgagagat atcatctata
    18541 ccgtttacgg cagggaaatc gcggctaatc tgcttcctgt ggagatgggg gaggagccgg
    18601 tgaagctttc aggctttatt ggaaagcctc tgatcgccag gggaaacagg aattttgaaa
    18661 cgtattttat caatgggcgt tatattaaga gcagcctgat cagcaaggct gtcgaggacg
    18721 cctacaagcc gtttatgatg cagcacaagt atcctttcac catgctgaat tttgccattg
    18781 atccctcctt tttagatgtg aacgtccatc cggcgaaaat ggaactgcgc ttcagggatg
    18841 gagagatgat ctataaaatg gtttaccata cgatttccat ggccctgtca gagcgggaac
    18901 tgattccggg ggtggagctg ggacagactc agaagaaaga agctcctttg aaaccggtcc
    18961 atgtgcagag gccggaacca tttgaggaaa agcgccggga ggcggttcag gcttccgaaa
    19021 cttttaagac ttttaaggct tctgccccgg tttttgaaac aagaacttct gaccgtgttt
    19081 tggatccagg agaaggctta agaagccaga aaactgtgat ccgggaagca gagcctgagt
    19141 atgggcgcgc tgcagggcag acggttcggc aggaggagaa ggagcgggaa aataagaacc
    19201 aggagagtct gtttcagaaa gataagatcc agaaagatga gaatctgaaa aagccgcagg
    19261 agccgcaaga gcccaggcag atggatctct ttgaagaccg gcttctgacc agggaggcca
    19321 gggcggagca cagactgatt ggccagctgt ttgacaccta ctggctggtg gaatacaggg
    19381 ataagctcta cattatcgac cagcatgcgg cctacgagaa ggtgctctat gagaagacca
    19441 tggctacgtt aaagagcaga gaatatactt cccagctggt gagtcctcct gttattctca
    19501 cgctgaatga ctcggagcag cttcttttgg aacggtacat ggaccatttt actggcattg
    19561 gctttgagat tgagcccttt ggcggcaggg aatacgctgt gcgggccgtg cctgccaacc
    19621 tgttttccat tgccaagaag gatcttctga tggagatgtt agacagtctg tcggaggagg
    19681 cggagagaag cggcgcagat atgattaacg acaggattgc gtccatgtcc tgcaaggcgg
    19741 ctgtaaaggg aaaccaccat ctttcggcgt ctgaggcgga aacgctgata gacgagcttc
    19801 tggagctgga aaacccatat gcctgcccgc acggaaggcc cacaattatt tccatgagcc
    19861 ggtatgagct ggagaagaaa tttaagcgga ttgtgtaaga aaagcaggtg atggaaggag
    19921 gaaacacaga tggaagagaa acggcccctt attattatta caggccctac ggcctctgga
    19981 aagacggcgc tttccattga gctggcaaag cagattggag gagagattat cagcgccgac
    20041 tccatgcagg tgtaccgcca tatggatatc ggatcggcca aggtgacgaa ggaagagatg
    20101 gacggcgttc cccaccacct gatcgacgtg ctggatccgc cggaagaatt taatgtggtg
    20161 cggtttcagg agatggcgaa aaaagctatg gaggagattt acggtcgggg aaacattccc
    20221 attctggcag gaggaaccgg tttttatatc caggcgcttt tatacgatat cgattttacg
    20281 gagacagaag aacagtcagg actcagagag gagctggagg agacggccag gacaaagggc
    20341 gcctcggctc ttcacgtcat gctgagggag atagacccgg aatctgcaga ggcaatccat
    20401 gaaaataatg tgaagagagt gatccgggcc attgagtttt acagacagac agggagaaag
    20461 atctcggatc acaaccggga ggagagggag aaaacctcgc cctatcagtt tctctactat
    20521 gtgctggatc tgccgagacc tctcctctac agccggattg acgaacgggt agaccggatg
    20581 atggaaagcg gactggtgga ggaggtcagg gctcttcagg cgatgggctg caccagggat
    20641 atggtttcca tgcagggcct ggggtataag gaaatattag attacctgaa cggggaactg
    20701 actctggacg aggcagttta tattttaaag cgggatacca gacatttcgc aaaacgccag
    20761 ctgacctggt ttcgcagaga gcgggacgtg cggtggctcc agccggaggc gttcggcggc
    20821 agcagggagg agatgcttga cgctgtgtta aaggactgca gggaagcgtt cggggagcgc
    20881 tggctcagga agcagccgga gctttagaag atataaaagg aatcagatta agaaattcaa
    20941 ttaaggaaag aaaaacagaa aggcagatac caatggattt aacatcaatg tacaaaacgc
    21001 ttggcatcag cgaagaggtg ctgaaatttg gactggaaat cgaggagacg ttaaagaaac
    21061 ggtttaaaaa ggtggatgag acggcagaat tcaaccagtt gaaggtgatt tcggccatgc
    21121 agcagaaccg tctgagcgat attcactttt caggaaccac aggctacggc tacaacgatc
    21181 tgggaagaga gaccttagag caggtgtacg ccagcgtatt ccacacagag gacgccctgg
    21241 tgcggccgca gattacctgc ggaacccacg cgctttacac ggctctggcg ggaaatctgc
    21301 gtcctggaga cgagcttctc tccccggtag gaaaacccta cgatacactg gaagaggtaa
    21361 tcggaatcag gaattccaac ggctctttaa gggagtacgg tattacctac agccaggtgg
    21421 atcttttgga ggacggaagc tttgacttcg acggaatcag gaaagccatt aacgagcgga
    21481 caaagctggt tacgatccag cgctccaagg gctacgcaac caggccgact ctttccgtgg
    21541 agcggatcgg ccagctgatt gcctttgtaa agagcattaa gccggatctc atctgcatgg
    21601 tggacaactg ctacggagaa tttgtggaga ccatcgagcc cagcgacgtg ggagccgata
    21661 tggtggtggg ctctctgatt aagaatccag gcggcggact ggctcccatc ggcggatata
    21721 ttgcaggaac caggaaatgc gtggagaacg cggcgtaccg tctgggctcc ccgggacttg
    21781 gaagagaggt aggagccagc ctgggcgtca accagtcctt attccaagga ctgtttttag
    21841 cgcctaccgt gacggcaggt gccttgaagg gagctatttt tgcggcggct gtctatgaga
    21901 agctgggctt ttccgtggtg ccggacagta cggaatcacg ccacgatatc atccaggcgg
    21961 tgacgtttgg aaagccggag ggagtcatcg ccttctgcga gggcatccag gcagccgcgc
    22021 cggtagacag ctttgtgacg ccggagccgt gggacatgcc tgggtatgat tcccaggtga
    22081 ttatggcagc aggcgccttt atccagggag cttccatcga gctgtcagca gacggcccta
    22141 ttaagccgcc ttactcagta ttcttccagg gaggactgac ctggtatcac gcaaaacttg
    22201 gaattctcat gtccttacag aaactgaagg acgcaggaat tgtgacaatt taactgaaaa
    22261 aatatgggag aaatttctgg ttttttaaga aatgatttcg aaaaaaatag aaattctcgt
    22321 atatacacgc cggagcgatt gtgataaaat aggtaagcag ccatccgttt tcctttgtac
    22381 ctggagaggc aatggagaag aggaggccga tatggattac cagactatga aagaaatacc
    22441 ggggcctgac aggccctatg agaagtgcga gcgcctgggg gcggaggccc tgacagacgc
    22501 ggagctgctc tcgatcatta tacgcaccgg agccagagga gagcattctc tggctctggc
    22561 gcagaaaata ctgagcctga atgaaccggc ggggatttta ggcctgctgc acctctcgct
    22621 gccggagctt acggcagtga aggggatcgg acgagtgaag ggacttcaac ttctgtgcat
    22681 tggggagctg tcgaagcgga tatggaaaac cctggccgtc caggagacga agcattatga
    22741 gagccccgaa gagattgcgg ctttttatat ggaagatatg cgtcatatgg agcaggaaga
    22801 acttcatttg atgatgttta atacgaaaaa tatgctgatc cgggaatcct gcctgtttcg
    22861 cgggacggtc aatgcgtctg tggcttcttc cagagaaatt tttatcgaag ctctgcgcta
    22921 ccacgccgtg cggctggcgc ttgtccataa tcaccccagc ggggatccgt ctcccagccg
    22981 tgaagatatc gggctgacag agaaggtgga aagagcgggg gaacttctgg gccttacgct
    23041 tcttgatcat gtgattatag gagataattc ctacttcagc tttaaggaac ggggaatgtt
    23101 ataaaatatg aaaaacagta aatatattct ggcgggtctg tcctttttct gtattgtgct
    23161 gatcgccgtt acatcgatta ataacagtat cctgacgcct ctgcggacag gagtgggata
    23221 tgttttaatt ccattccagt caggagtcaa tgcgattggg acgagtctct acaatcatat
    23281 cagggatttt tccactatgc aggaagcaca ggcggaaaat gaggagctga agggccgcgt
    23341 agcggagctg acagaggaga ataaccgtct gcaggctgag cagtacgagc tggaacggct
    23401 gagggagctg tatgccctgg atcaggacta tatgcagtat gagaaggtgg ctgcaagagt
    23461 gattgccaag gactctggaa actggttcca gattttcagg attaataaag ggtctaacga
    23521 cggcattaaa gaaaacatga atgtaattgc cggaggagga ctggtgggaa ttgtcaccga
    23581 cgtgggggcc aattacgcca cagtgcgttc tatcatcgac gacgccagcc gcgtcagctg
    23641 catgtccatg cgctccggcg acaactgcat tgtcagcgga gatctgactc tgttccagga
    23701 gggactttta ggcctggatc acgtgaagaa ggaggctgac atccaggagg gagacaagat
    23761 cgtaacctcc aatatcagcg acgtgttcct gcccggaatc ctggtcggct acgccacaga
    23821 gctgaccaca gattccaata acgtgacgaa gtcaggacag attgttccgg tagctgaatt
    23881 tgacaacctt caggaggtgc ttgtcatcac ccagctgaag gacggcggcg aggagtagag
    23941 attatggtta agaacagcat caggaaaatc attttaaata ttatccttct gatcctggct
    24001 tttacgattc agatctgcgt gtttcctcag attgcctttt tatcagcggc gccgaatctg
    24061 cttttgatcc ttgtgtttat caacggcttt atagacggga gggcagccgg catctgctac
    24121 ggcctggtgg cggggctgtt tatggatctg ttttacagcg gtccctttgg attttacacg
    24181 ctgtttttta tcaacgcagg gtatattaac ggtgttttta ccaaatatta ctatgaggat
    24241 tacattaccc tgcctctgat tttgagtatc accaatgatt tagcctacaa catgtatata
    24301 tatgtgttcc gtttcctgat acgggccagg ctggatttcc tctactattt caaggagatc
    24361 atggtgccgg aaatcatttt tactaccgta accacgctgc tggtctaccg cctccttctg
    24421 tttatcaaca gaaagctgga ggaacggatg caaaggagag attctaccat tgtttaggga
    24481 tttactggaa tatttaaagg agcttttaaa aaaagtcgtt acctcccggc tctttgccat
    24541 ctccctggtg tttgtgctta tgtacggaac gctgatggcg cgtctgtttt cacttcagat
    24601 tgtgcatggc gaggagtatc aggatgaata tatttcgctg actgaaaagg tgattaagac
    24661 agccagcacc agaggtaata tttacgacag aaacggaaac gtgctggctt acaacgagct
    24721 ggcctacaac gtgacagtac aggacatagg tgcctttgaa aacagcgccg gctggaactt
    24781 tatgctatgg gagctggtgg agatactgaa cgaacacggt gaaacggtaa agggcgatct
    24841 ggagatcact gcagacgcgg agggaaacgt atcctatacg tcggcctccg aaagcgccag
    24901 actccgtttt ctgcgtgacc tgtacggctt aaagagcgta gacgagctgg atgatccaaa
    24961 aggagagtat ccgtccaatg taacggcgga ggaacttctg agggagcaga tgcgcatcta
    25021 caagctggat gagatgaagg atgaaaacgg aaatttggtg gaggttcccc tggacattgc
    25081 cgtccagatt gtaaacatcc ggtataccat gcgtttcaca agctttagaa agtacgaagc
    25141 cacgactgtg gcggaaaata tcagcgagga gacgatggcg gatatcctgg aacacacggc
    25201 ggatctgccg ggagtgaaca tcgaggaatc taccatccgg gtttacaacg atgcgattta
    25261 ctttgctcct gtcattggat acacgggaaa agttacgaca gacggtctgg aggagttaaa
    25321 aaaacagagc gacgactatg agctgaacga cgtggcgggc cgtacgggaa tcgaatcctc
    25381 tatggagctg gatctgaaag gaacgaaggg gtctcagact atctacgtgg acaatatggg
    25441 aaaaattctg gagacagcca acgtggtgga gccaaaagcc ggaaacgacg tctggctttc
    25501 gctggatcgg gatcttcaga aggccattta ccacattttg gaaaagcagc tggcaggtat
    25561 tctgaccaac gtgctcgtca accaggagcc ggaggagatt aagaatgtgg acgcctccga
    25621 aattaagctt ccgatcaagg acgcctattt tcagctgatt aacaacaacg tcctctcatt
    25681 ccacgacttt gcgtcagagg aggcctctga cacagaacgg cagattaacg ccaagtttga
    25741 aagcgccaga gcaaggattg aggcggacct gaagaatgag ctgacaagca gcgcgcccgc
    25801 tcccatgaac gccctttcag aggatatgca ggcctacatg cagtacattt acacccttct
    25861 ggcctctgac agcgagaagc tgatcctctc ctctgagatc gacacaaaga gcgaggagta
    25921 cgaggcctgg aaggcaggca gcctgagtct gaaggaatat ctgtattacg gcattgccaa
    25981 caactggatt gacaccacca ggctggaaat cgagaacaag tattccagcg cggacgacgt
    26041 atatcaggtt ctggtagagc atatttttga aattctcacg gataacgacg agttttccaa
    26101 gaaaatttac cagtatctga tttataacga taccgtgttg ggaagagagc tctgcctggc
    26161 tctctacgac cagggcgttc tggcctatga cgaagcccag gtggctgcgc tgagacaggg
    26221 agacgcgaac tacacctact cctttatgat gcagaagata cgaaacgtgg aactgacgcc
    26281 ggcccagctg gccctggatc cgtgtactgc gtcctgcgtg gtcacagacg ttcacacggg
    26341 aaaggttctg gctctcgtca cctacccggg ctatgacaac aacaaaatta ataatgtaga
    26401 ttattttgcc caggtgaaca gcgatctgtc aggacctctg agaaataatg cgacgacaac
    26461 gctgaaggct ccaggatcca cctttaagcc tatcacagcc attgcaggac tggaggaagg
    26521 cgtgatcgga ctgggagagc cggttgtctg cgacggcgta tttaaggaga tcagcaatcc
    26581 cttaaagtgt ctgggacatc acggcccgct aaacgtagtg ggaggaatca caaattcctg
    26641 caacgtttac tttgcggagc tggcccacag aatggccatg gagggcgaca cctacaaggc
    26701 ggacaagggc ctggagacac tgaaaaaata tgcttccatg ttcggccttg acgagacctc
    26761 cggaattgag attttcgaat cggaacctca tatcagtgac atggatccgg agcgttctgc
    26821 cattggacag ggtacccacg cctttgcaaa cgtacagctg gccagatatg tgacggctct
    26881 cgccaaccgg ggcacggtat tcgatttaag ccttcttttg aaggagacgg actccaaagg
    26941 aaatctggtg caggagtttg cgccgaaggt acatgagcag ctggatattg cggcttccac
    27001 ctgggatgct gtattcgagg gtatgagagg agtggtgaca aggagcgcca gattccagga
    27061 ccttccggtt aatatcgccg gaaagacagg tacggcccag gaggtaaaga caagaggaaa
    27121 ccacgcgttc tttatttcct ttgcgcctta tgagaatcct gaaatcagtg tggcagtcaa
    27181 tattccaaac ggctacaact ctgccaacgc ggccctcact gcaaaatcag tgtaccgcta
    27241 ctattacggc tacatgagcc tggatgagat catgagcgca ggagcgttaa acgcatccag
    27301 agagacaatt aatggagaat aaatatttaa taaagattta atactggaaa cttttggaat
    27361 tttagggtaa aataagaatg taaactgaat acaggaggat attgcactat gagtgaagtc
    27421 attgtgatta catccggaaa aggcggcgta ggcaaaacga ctacctccgc aaatgtggga
    27481 acaggccttg ccatactggg gaagagagtg gtgctgatag atacagatat cggcctcagg
    27541 aacctggacg tggtgatggg actggaaaac cgcattgtct acaacctggt agacgtggtg
    27601 gagggaaact gtcggatgaa gcaggcgctg ataagagaca aaagatatcc taacctgttt
    27661 ttactgccat ctgcccagac gagagacaaa tcgtcggtaa atcctggaca gatggtcaaa
    27721 ctggtcgctt ctctgagaga ggagttcgac tacatacttc ttgactgccc ggccggtatc
    27781 gagcagggct tcaaaaatgc cgttgcagga gctgacagag cgattgtagt gactacgccg
    27841 gaggtatcgg cgattcgtga cgcagaccgc attatcggac ttctggaggc agatgagatg
    27901 aagcatatcg atctgatcat taaccgtatc cgcatggata tggtaagacg cggcgatatg
    27961 atgtcggtag acgatgtgat ggatattctg tccgttccag tgattggcac catccctgac
    28021 gacgaggata ttgtaatttc caccaatcag ggagaacctt tggcagggat gaacggcttc
    28081 gccggacagg cgtatctgaa tatctgcagg agaatcctgg gagagtccgt accgtttctg
    28141 aattttgaca acagccggaa tctctggtca aaaatcacct gtcttttaaa gcgggcataa
    28201 ggagggagac aagatgggca tcctcagact gcttggcaga aataattcag gtgaaatagc
    28261 gagaaagcgt ctgaagcttc ttctggcatc tgaccgggca ggctgctctc cggatattct
    28321 ggagatgata cgcacagacc tgctccatgc agtttccaga tacatggagg tgaaggagga
    28381 ggacgtcatc gtacagatga taagaacctt gccggacggc agaaaaacgc cggctctatg
    28441 cgctacgata ctggttcata acattaagca gagcaaggaa acatttacag catgatattc
    28501 aactacagct taaagaatta caacttccgc attgtaattt acatgatttt tttaagtgtt
    28561 gcgggaatcc tggtgctgag aagcgccagc ggcggagatc cgtcgattgt cggaaagcag
    28621 attctggggg tggcagtatc gtttgtatgc tgtctgctga tttccatgat cgattaccac
    28681 aggattttcc gcctgagtac cttgatttac gcaggctgcg ttgcccttct ggctgccgtt
    28741 ctgcttacag gacacagctc cggaggagca acgcgctggc tgaagatttt tggctttacc
    28801 attcagccgt ctgagttttt gaaggtaggt ttgatagtgg ttctctcctg ttatctggca
    28861 aaaaatcacg agagaatcaa taaggtatcg gttctgggaa cgattgtgct tatgatagcg
    28921 cttccggtag ggcttgttct ggctcagccg aatctgtcca ccagcattgt tattacgata
    28981 ccgcttattg ttattatcta tgcggctggg ctcagctata aatggatcgg cggggtactg
    29041 gcggcgggga ttcctgccgg cgggctgttc ctttatctgg cccagtttgg gatagtacca
    29101 ttcctgagag agtatcaggc ccggagaatc ctggctaaga ttttccatga cagcgcccag
    29161 tatgcggacg caaacaatca gcaggataaa tccatcatgg ccatcggttc cgggcagctt
    29221 tggggaaagg gactgaataa tgcaggcgta ggttccgtaa aaagcggaaa ctttgtggcg
    29281 gaggatcaga cggacttcat ctttgccgtg attggcgagg agctgggttt tgtgggcagc
    29341 atggtcatta tttctgtgct ggctctcctg gtgtttgaat gtcttctcac agccagccgc
    29401 gccaaggaca tgggcggacg ccttgtctgt attggaatgg cggttctcat aggctttcag
    29461 ggctttgcga acattgccgt tgccaccggg atttttccga atacgggact tccccttccc
    29521 ttcatcagtt ctggtatcag ctctgtgctg agtatttatg ccggtatggg aattgtacta
    29581 aacattgaac ttcagagaaa aagcagcaat aattaaggag gtagcccagt atgaatatag
    29641 ggttggtagc tcacgattcg aaaaaaaagc tgatgcagaa tttctgcatt gcgtacagag
    29701 gcgttttaag caggcattct ctttatgcca cgggaactac aggaaggctg atagaggagg
    29761 ttacgaatct gaatgtgtat aagtatcttc cgggacatct gggaggcgct cagcagctca
    29821 gctcgcagat tgaacacgat cagatggatc tggtgatctt tctcagagat ccgtctaccg
    29881 ccaaatccca cgaaccgaat gtcaacaatg tggtgatgat atgcgatatg tataacattc
    29941 ctatcgcgac caatgtagcc acagcagaac tcctgattaa atctttggag cgcggcgaca
    30001 tggagtggag agaaatgtac agatagacag ggaagttcct taagaaagca ggagagcagc
    30061 gacttgaagc atttatttca taagcagatg tttggattgg cagccgcgct ttttctcacc
    30121 ggctgcagtg gaaacacgct ggaagagccg tattcctttg cggatcgggg aagcaatctg
    30181 ggggtgtcgg agggttcagc ctcactggcg cctctttttg cttctgatct gtgcgtgatt
    30241 gacggagaac ccgccgatga cagtacagaa tttaccgggg aggcgggggc tgtattcggc
    30301 atcacagacc aacatgtaat atacagtaag aacgcctata agcagctcta cccagccagc
    30361 attaccaagg tgatgacggc gctgattgcc attgaggagg gagagctttc cgatacggtc
    30421 caggtgacaa aggacgctgt cattacagag tcaggcgcgt ctctgtgcgg catcaagccg
    30481 ggagacacgc tgactatgga acagctgctg tacggactcc tgattccgtc aggaaacgat
    30541 gcggccaacg ccattgccgt tcacatgtcc ggcagcgtgg aggcctttgc cgggcgtatg
    30601 aatgagaaag ccagacagct gggagccacg cagactcatt ttaaaaaccc cagcggtctg
    30661 tctgatccgg aacactatac cacagcctat gatctttacc tgatattcaa cgaggccatg
    30721 aagcttccga aattccggga aatcatagga gctgacgcct acacggcgtc ctacacggac
    30781 gcacagggaa acgcagtttc caaaacctgg aaagtgggaa actggtatca gaacggagag
    30841 acagagacgc cggaaggcct gacggttctg ggggggaaga cgggaaccac ccaggcggcc
    30901 ggctactgcc tgattatggc agaacaggat gaagcgggga aagaatacat ctccgttgtg
    30961 ttaaaagcag agaaccgaca gggactttac aaaaatatga ccaatataat tactaaaatt
    31021 gtcgattagt gattgatttt ttcgggcatt tatactataa ttaattgcat aataaaagat
    31081 tttttataca acttaaataa agtccaagga ggagatttga tatgattcag attatttcgg
    31141 gaaacaaggg aaaaggaaaa actaaatatc ttcttgacat ggccaataca gccatcaaag
    31201 aatccacagg ttcaattgtg tatctggaca aaagctccaa gcacatgtat gagctgaaca
    31261 acaggattcg tttaatcaat gtaaatgagt atcccatcac ttccagcgag ggctttattg
    31321 gttttatctg cggtatt
//
LOCUS       DBMDUW010000027        29476 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1155_length_29476_cov_2.889226, whole genome shotgun sequence.
ACCESSION   DBMDUW010000027 DBMDUW010000000
VERSION     DBMDUW010000027.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 29476)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 29476)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29476
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1155_length_29476_cov_2.889226"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..1886
                     /locus_tag="ACZPCR_06815"
     CDS             <1..1886
                     /locus_tag="ACZPCR_06815"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: protein motif:HMM:NF012301.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="hybrid sensor histidine kinase/response
                     regulator"
                     /protein_id="HIR1230624.1"
                     /translation="MDPYLKRILNGIHEGTLEEDHPYVINPNGEKRGVYYEKMDNGWT
                     CIVTIPYKELLGNFWNVTLWYMGLFNFCFALVLFMGVNSCLLSRKMKRINETVQVLGN
                     SFYAIYRVNFKNDVYDMIKGSEYVRSQVPEKGRYSDFLKIMGGVIEEHAYQEFIESFS
                     LSNINHLVSQKVQDYGGDFRRRFQDGYRWVSIRFLYDESLNKDEAVLCFREVDEEKKS
                     QLKHQHILETALDRAKKNEDAQNRFFSAMSHDMRTPLSAIIGMTELAEKHPEDTAQVK
                     SYLRRIGVSSRQLLGLINDILEMSRVQKGKITIENSDFDLKAAIGDYTAPFAIQAERE
                     NKKFSVSFQARNHRVRGDAFRLGQVMNNLLSNAFKFTKPGDSISVCIRQEELSEDRFC
                     IVVSDTGAGMSEEFLTRLFLPYERETRFGAKYIAGTGLGMAIVKSIVSQMDGQIKVDS
                     RLGEGSMFTLLLPFEVLPDAKEKEHTETALEGSEAKEGSEREYTNLSGLKILLAEDNE
                     INMEICREMLGMAGIQVTEAWNGREALEAFRASSVSHFDAVLMDMQMPEMDGCAAAMA
                     IRNLKNEREDAETIPIIAITANAFSEDIAATEAAGMNAHISKPIDFPVLCRTLERLTG
                     NRV"
     gene            1977..2870
                     /locus_tag="ACZPCR_06820"
     CDS             1977..2870
                     /locus_tag="ACZPCR_06820"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: protein motif:HMM:NF005491.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008478 - pyridoxal kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009443 - pyridoxal 5'-phosphate salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HIR1230625.1"
                     /translation="MKKTAVIHDLSGFGKCSLTAAIPILSVMGVQAVPLPTAVLSGQT
                     GYGDYVCEDFTAPMSSISKLWKRQAVEFDGIYSGFLLNERQADQILEFIRDFSGRETL
                     VVVDPVLGDNGKRYDIFDSQMELAAGRLAEQAHVITPNLTEALLLGRQARESIPDWKA
                     VRLMGRQERLALAEDLAEVLTESYRLRGAVITGIELSQNGFPQIGNLVLAEKGTPQWT
                     VSPKTGGSYSGTGDILASIVTASLVNGGSLFDSVCRAADFIEKGIREAAREQTDRNDG
                     ICFESCLWELGREALGSEKSL"
     gene            2854..3390
                     /locus_tag="ACZPCR_06825"
     CDS             2854..3390
                     /locus_tag="ACZPCR_06825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HIR1230626.1"
                     /translation="MKKVCDRASDKKLELMSQAAVMAALTAALTLWLHIPAGLNGGYI
                     HFGDAVIYLAAALLPKPYAMAAGAAGGVIADLLTAPLWAPATLLIKPLLVLPFSNGGE
                     RIVTRRNTAALVLAFFLSASGYFLAEGLMFGFHTAFLVSVSGSAVQSGGSALAFLAAG
                     GALDRLQVKKRWRAGSRG"
     gene            3422..4027
                     /locus_tag="ACZPCR_06830"
     CDS             3422..4027
                     /locus_tag="ACZPCR_06830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006444543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HIR1230627.1"
                     /translation="MADIVYQYKNQVYLNITNRCPCRCEFCIRSHGDSVGDAENLWFE
                     REPELEEIFDAVDSFDFSGCREIIYCGYGEPVMALDKMKQISPFLRERFPDCRIRLNT
                     NGLGDLIYGRSTAGEVCRLADSISISLNMPDADSYEAVVHPVYGKKAFASMLQFARDC
                     KAILGDVRFTVVDIIGREKVEESRRLAQRLGIPLRVREYSE"
     gene            4258..5085
                     /gene="licT"
                     /locus_tag="ACZPCR_06835"
     CDS             4258..5085
                     /gene="licT"
                     /locus_tag="ACZPCR_06835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002603874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HIR1230628.1"
                     /translation="MRVNKVINNNIVSALDSEGKEIVVMGRGLGFGAKPGKEIPEAKI
                     EKIFRLDSQNTMDRFKELLSNLPLEHIQVSAEIINYAKSVLNRSLNQNIYVTLTDHIN
                     FAIERFRKQMRFSNPLLSEIKAFYKEEYLIGEYAVALIEKEIGIWLPIDEAGFIALHV
                     VTAEYNTAMRETIDITNLIQNVVGMVRDYFHVGLDETSLNYQRFVTHLRFLAQRIVAG
                     ELLDGGNPEFNRLISQMYPEEYACSLKIREHIKSVYSHDVTDEETAYLAVHIKRIRD"
     gene            5104..5592
                     /locus_tag="ACZPCR_06840"
     CDS             5104..5592
                     /locus_tag="ACZPCR_06840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013272837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HIR1230629.1"
                     /translation="MFSSLKKMFGGKEEKKTVLAPAAGKAVSLKEVNDPTFSQEILGK
                     GVAIIPSEGKIVAPADGTISVFFETKHAVSISAENGAEIIVHVGLDTVNLKGEHFTAH
                     KQQGDKVKAGELLLEFDMEAIKAAGYDVITPVIICNTPDFPDMVCHTGQDVKELDTII
                     EL"
     gene            5606..5878
                     /locus_tag="ACZPCR_06845"
     CDS             5606..5878
                     /locus_tag="ACZPCR_06845"
                     /inference="COORDINATES: protein motif:HMM:NF012599.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HIR1230630.1"
                     /translation="MKILTIAVQTAEGLHVKPASQLFMAARDFSCRITASCREAQADC
                     KSILELLGLGAAGGERLVLSFDGPDEEAAERAFRRLTEKSEEFSYI"
     gene            5979..7442
                     /gene="nagE"
                     /locus_tag="ACZPCR_06850"
     CDS             5979..7442
                     /gene="nagE"
                     /locus_tag="ACZPCR_06850"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004844031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HIR1230631.1"
                     /translation="MKFLQKLGKSLMLPVACLPVCGILMGIGYALCPSTMQGGTVEGL
                     KEIIGFFLVKAGGALIDNMSWLFAVGVAVGMSDDNDGTAGLAGLVSWLMMTKLLNPAV
                     VGTLTGVAADAVDLSYSKIETQFIGILAGIIGAMCYNRFKTAKLPDWLSFFSGKRCVA
                     IVTALVSIVVAAVLFFVWPIVFGALVALGKGIMSLDAVGAGIYAFFNRLLIPFGLHHA
                     LNNVFWFDTIGIGDLTHFWAGETSADVTWSLGMYMAGFFPCMMFGIPGAALAMVQCAK
                     KEKRKIVIGLVGSAAVAAFVCGVTEPFEFAFMFLAPVLYLVYSLLYGIFTTITVALGF
                     RAGFSFSAGLTDLVFSAQLPAAAKTMLIIPLGAAAFVVFYLVFRVLITKLDLKTPGRE
                     DDDTESEKAVSLSNNNYTEVASIILEGLGGPSNVTSIDNCITRLRLEVKDQALVDEKK
                     IKSAGIAGIIRPGKTSVQVIVGTQVQFVADEFKKLCK"
     gene            7583..8350
                     /locus_tag="ACZPCR_06855"
     CDS             7583..8350
                     /locus_tag="ACZPCR_06855"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009242909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HIR1230632.1"
                     /translation="MILAIDVGNTNIVIGCIDKEKCHFIERLSTVRIKTELEYAIDIK
                     SVLDIYHVCPEEIEGGIISSVVPQITTNIKLAAEKILKKEILVIGSGIKTGLDIRIDD
                     PGQLGADLVAASVAGIAEYPVPMMIFDMGTANTVCVIDREKRYLGGMIYPGLGVSLDS
                     LTAHASQLGGISLEAPERVIGRNTIDCMKSGVIYSAAAAMDGIIDRIQEEMGETLTVI
                     ATGGLAKCIVPHCRREVILDDDLLLKGLLVLYDKNRR"
     gene            8356..11085
                     /locus_tag="ACZPCR_06860"
     CDS             8356..11085
                     /locus_tag="ACZPCR_06860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007858906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HIR1230633.1"
                     /translation="MGALSENQLKKHICAGIVAHVDAGKTTLSEALLYLSGSIRKLGR
                     VDNQDAFLDTCQLERARGITIFSKQAELQWNGTSVTLLDTPGHVDFSAEMERTLQVLD
                     YAILVISGADGVQGHTETLWRLLARYEIPVFLFINKMDQPGTDRDALMRELKKRLDEG
                     CIDFQEEGTEEFYEQAAMCEEKLLDAYLETGTVEEEEIRRLIQKRKLFPCFFGSALKL
                     QGVKELLDGFCRLSKLPCYPEDFGARIYKISRDGQGNRLSHLKVTGGILKVKTAPVSG
                     CPDKINQIRIYSGSRFETVQEAPAGTVCAVSGLSSSFAGQGLGFEEELAAPVLEPVLT
                     YRLILPEGCDAASFLPKLRQLEEEEPLLRVLWNESLQEISMQMMGQVQIEVLKSQMEE
                     RFGVLAEFGTGSIVYKETIAGPVEGAGHFEPLRHYAEVHLLLEPGEPGSGLSFGSLCS
                     EDVLDKNWQRLVFTHLEERQHPGVLTGSPITDMRILLTAGRAHPKHTEGGDFRQAVCR
                     ALRQGLMEAESLLLEPWYSYRLEVPEPSIGRAMNDMEQRSGTCVLEESRDGMAVLTGQ
                     APAICLTEYQAEVTSYSRGRGRLFCSLLGYRPCHNTEEVITRIGYDPERDTDNPTGSV
                     FCAHGAGFAVPWNQAKAYMHVESGLHLDREDEKQDGQPRGFKNPGSSTRQEAAEEMWM
                     GTEEIDAILERTFYSNSRGKDTPRKKYSSGVRKQRRFPEEPSSQPIRSALKPAGKKQE
                     YLLVDGYNVIFAWERLKALAEDNLDGARMALLDMLCNYQAVRQCSLMVVFDAYRVEGH
                     TTEVSAYHNIQVVFTREAETADQYIEKFAHENAGRFDVSVATSDGVEQVIILGQGCRL
                     ISSRELEQELERMNQALREEFLLETEKKGIRLSDLLTEEELLRLRQEIEPETE"
     gene            11102..11932
                     /locus_tag="ACZPCR_06865"
     CDS             11102..11932
                     /locus_tag="ACZPCR_06865"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002564992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HIR1230634.1"
                     /translation="MADIHWITDFSAPELDIYARLSEGQLLHYHEPDTGIFIAESPKV
                     IERALDAGYEPVSFLTDPKCMEGEAKDILARCTGIPVYAAKFDILTKLTGFQLTRGLL
                     CAMRRKALPDVKSLCAGLTRIVILENVMNPTNVGAVFRSAAAMNMDAVLLTPGCSNPL
                     YRRASRVSMGTVFQIPWTFFDEKKGAWPEGGMKILKELGFKTAAMALREDSTTLDDPA
                     LKAEEKLAVIIGTEGDGLASETIADCDYTVRIKMARNVDSLNAASAACLAFWELGKRL
                     "
     gene            12043..13074
                     /gene="plsX"
                     /locus_tag="ACZPCR_06870"
     CDS             12043..13074
                     /gene="plsX"
                     /locus_tag="ACZPCR_06870"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013272585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HIR1230635.1"
                     /translation="MIRIAVDAMGGDNAPEELVAGAVEAVKEKSEIKVLLIGQEDAVN
                     RELSKYTYNKEQIEVVHASEVIATEEPPVNAVRKKKDSSLVVGMNMVRKGEADAIVSA
                     GSTGAILVGGQVLVGRIKGVERPPLAVLIPTDKGVSLLLDGGANVDARPSHLVQFAKM
                     GSIYMEHAMGVKHPRVAIVNIGAEEEKGNALVKETFPLLKECGDINFTGSIEAREIPH
                     GGADVIVAEAFVGNVILKLYEGVGAALISKVKEGMMTSLRSKIGALLVKPALKTTLKS
                     FDASRYGGAPLLGLKGLVVKTHGSSKRTEVKNSIIQCLTFTEQGVNAKIQESLREKEN
                     REAGLSDGI"
     gene            13064..13294
                     /gene="acpP"
                     /locus_tag="ACZPCR_06875"
     CDS             13064..13294
                     /gene="acpP"
                     /locus_tag="ACZPCR_06875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008725969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HIR1230636.1"
                     /translation="MEFEKLQKIIAEVLNVEPEEIAMETTFVDDLGADSLDIFQIVMG
                     IEEGFDIEIPTEAAERIVTVGDAAEQIKNALN"
     gene            13436..14140
                     /gene="rnc"
                     /locus_tag="ACZPCR_06880"
     CDS             13436..14140
                     /gene="rnc"
                     /locus_tag="ACZPCR_06880"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007865052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HIR1230637.1"
                     /translation="MTHAHLNELQGKIGYSFKDSSLLTLAMSHSSYANEKHLSKLGCN
                     ERLEFLGDAVLEIVSSDFLFHRFPDMPEGDLTKTRASMVCEPTLAYCAEQIDLGSYLL
                     LGKGEDATGGRTRNSVVSDAMEALIGAIYLDGGFTSAKEFILNFVLNDMEHKKLFYDS
                     KTILQEIVQARGTELLSYELLEETGPDHNKTFQVAALIGSQEISRGFGRTKKAAEQRA
                     AYQAILKLKAEENKGV"
     gene            14148..17735
                     /gene="smc"
                     /locus_tag="ACZPCR_06885"
     CDS             14148..17735
                     /gene="smc"
                     /locus_tag="ACZPCR_06885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002564306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HIR1230638.1"
                     /translation="MYLKSIEIQGFKSFANKILFEFHNGITGIVGPNGSGKSNVADAV
                     RWVLGEQRVRQLRGGTMQDVIFSGTEIRKPQGFAYVAITLDNSDHKLPIAYDQVTVSR
                     RLYRSGESEYKINGSACRLKDINELFYDTGIGKEGYSIIGQGQIDKILSGRPEERREL
                     FDEAAGIVKFKKRKLIAQRKLDDEEQNLVRVKDILSELEKQVGPLKLQSEAAKEYLKL
                     KEELKGRDANLFLLEHKALQLQLSELDQKTSIVKGDWENASSQSEQLKKDFDRLEEEN
                     SASEEKIASTREEHSKSILLKESIEGQIAVLREQIRSEQLNEENRKERISSIDQELLG
                     KEEQKQEYEKQREETKKQVAQAEQALTQAGQTLSETEQEMARLSKESEAAKAAIISAL
                     NEKAGLAAKSQRYETMLEQVDVRRSEVTQKLLRFKSDESVQEEELKKEEKRLEQIQEE
                     LDRLTELEEETAFRLTAAEEDGAALAARLSRSQQDYHISHSKLESLKNLAERYEGYGN
                     SIRRVMEQKSRIPGIHGVVADLISTSKKYETAIETALGGSIQNIVTDREETAKELIEY
                     LKKNRYGRATFLPLTGISARGGFTQESALREPGILGLASDLVEVKDEYRTLIQYLLGR
                     VVVADTIDHAIALARKFRHTLRIVTLEGELLSAGGSMTGGSFKNSSNLLGRQRELSEL
                     QASCRKALQDVEETQKAIADNGRLKAQCAGEAARLRETKQEIVLRKNTAQMNMERLLG
                     KKQEIAESSADLVMENRELEFQLKEIRENRARLSREEEQLEQLQKEQEARSEQLSRKL
                     SDAQQQKEETAKLLSGAQLTAAGIRQQDRFIAENVSRILKEESSLKEERQRILDGSSE
                     SEAVISEKLAKIEQLGRQILEETSKAQRLEEALAQNSEEKERLAEKQKSFFRKREELS
                     EEIGRLDKELYRLESQKERLTERMSDQISYMWEEYELTYSGAQALKDEAPGTIPEIRR
                     AIEELKGNIKGLGNVNVNAIEDYREISERYEFLKSQNDDLAAAREALLKIIEELDTGM
                     RLQFEEKFAQIRQEFDKVFKELFGGGHGALILQEDEDILEAGIQIISQPPGKKLQNMM
                     QLSGGEKALTAIALLFAIQNLKPSPFCLLDEIEAALDDSNVDRFAKYLHKLTKNTQFI
                     VITHRRGTMVSSDRLYGITMQEKGVSTLVSVNLVESELEAQAKAGRTKF"
     gene            17767..18705
                     /gene="ftsY"
                     /locus_tag="ACZPCR_06890"
     CDS             17767..18705
                     /gene="ftsY"
                     /locus_tag="ACZPCR_06890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002564305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HIR1230639.1"
                     /translation="MSGGKKGFFGRLVEGLTKTRNSIVAGIDSIFSGFSAIDDDFYEE
                     IEETLIMGDLGIQTTMAIMEDLRQKVKDQHIKEPSECKELLIESIRSQMDLGENAYEF
                     ENRKSVVLVIGVNGVGKTTSVGKLAGQLKDQGKKVILAAADTFRAAAIEQLTEWSSRA
                     GVELIAQQEGSDPAAVIYDAIAAAKSRHADILICDTAGRLHNKKNLMEELKKINRIID
                     KEYPDAYRETLVVLDGTTGQNALSQAKQFMEAADITGIILTKLDGTAKGGIAVAIQSE
                     LGIPVKYIGIGEKIEDLQKFNANDFVNALFEKPAEQ"
     gene            18732..19973
                     /gene="ilvA"
                     /locus_tag="ACZPCR_06895"
     CDS             18732..19973
                     /gene="ilvA"
                     /locus_tag="ACZPCR_06895"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006567 - L-threonine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HIR1230640.1"
                     /translation="MCENEKKLTLEKFEEATEVVGKVISETKLVYSEHFSNMTGNKVY
                     FKPENMQYTGAYKVRGAYYKISTLSEEEKQKGLITASAGNHAQGVAYAAKLAGIKATI
                     VMPTSTPLMKVNRTRGYGAEVVLEGDVFDQALAHAYQLADEHGYTFVHPFNDLDVATG
                     QGTIAMEIIKELPTVDYILVPIGGGGLCTGVSTLAKLLNPKIKVIGVEPAGANCMQES
                     LKAGKVVALPGVNTIADGTAVQRPGDLLFPYIQENVDKIITIDDSELIVAFLDMVENH
                     KMIVENSGLLTVAALKHLDVKKKKIVSILSGGNMDVITMASIVQHGLIQRDRVFTVSV
                     LLPDKPGELAKVASLLAEQHGNVIKLEHNQFVSINRNAAVELRITLEAFGTDHKNTIV
                     AALSEAGYRPKLVKSKGVYEL"
     gene            20002..21258
                     /locus_tag="ACZPCR_06900"
     CDS             20002..21258
                     /locus_tag="ACZPCR_06900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HIR1230641.1"
                     /translation="MYQLDKNTPLGKNLWFFVKWSAVSTLIGLTTGLVGTVFGHLVMR
                     AGAYFNSRRWTLALLPAAGLMIVWIYHLLKEDKNRGTNMVIESIYTDSDISPGTAPAI
                     FLGTILTHFSGGSAGREGAALQMGGSIGNQIGRLMKLDEKDKKIAVMCGMSGAFAALF
                     GTPMAAALFSMEVISIGVMYYAALVPCTFSAFIGAAVSKHLGLAPEAFSIGPVPEFSL
                     KAALIMTVLGVLCALVSELFCIVLHRTEKVYRRYFPSPGRRIAAGAVLIIILTLLESS
                     FDYNGSGILLIERCFEGDVRYEAFLWKILFTAVTLEAGFKGGEIVPTFCIGAVFGCSF
                     AMITGQPFGLMTACGMLALFVGVTNCPISTLLIGFEMFGYQAMPYFVLVIAVSFTLSG
                     YYSLYSSQKFVYSKTKTEYINRKMEE"
     gene            21271..22605
                     /locus_tag="ACZPCR_06905"
     CDS             21271..22605
                     /locus_tag="ACZPCR_06905"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019239 - deaminase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HIR1230642.1"
                     /translation="MKTLIRHATVLTMDEKNTVFKNGCVLIDGDRIVKAGEEEELQAE
                     MESFGASQIIDGHGGILIPGLINTHCHVSMMPFRTLGDDCADRLRRFLFPLENDAMTR
                     KLVRLAARYGICEMLLAGVTSFVDMYYFEDQVAEACEELGIRGWLGETVIGQKTCDSE
                     EPYGGLAYAENFIRQWKGSNLVKPSAAPHATYSNSPEMLKKAYELSCKHDTLFTLHAS
                     EMDFEMEQFRREKNMTPSEFLYDLGVLSGRTLLAHCVYMTDRDMDLLAETGTSVAHCI
                     GSNTKGGRGVAPVPAMQKRQIPVGFGTDGASSGNTLDLFTLFKLFADFQKTAYHDRSL
                     FPAEDIVRIGTMGGAQALHAEKDLGSIEAGKKADLVIVETDSVNMFPCYNPYSALVYS
                     ANASNVDTVMVDGQLLVRGRQLVNADLAKIREELRQEMGPFMEAARQYGDML"
     gene            complement(22607..23539)
                     /locus_tag="ACZPCR_06910"
     CDS             complement(22607..23539)
                     /locus_tag="ACZPCR_06910"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002575344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase family protein"
                     /protein_id="HIR1230643.1"
                     /translation="MKTRIQTPKKILIIGSTCVDIIINVDHLPKTEEDIHPFSQSMAL
                     GGCAYNAANIIRQFGAPHTFISPVGTGVYGDYVRKELKQKGVPVLADVPDQENGCCYC
                     LVERGGERTFMSLHGAEYTFSRTWMEPFEKETFDITYVCGLEVEEPTGNELLGYLEDH
                     REQQIFYAPGPRGILIEREKTERMLALHPVLHINEAEACALSGCSQAREAAEALAHRT
                     GNTVIVTLGKDGACCLEKDGSFYQIPAYPAQVADTVGAGDSHIGTVMACLSLGYNMRE
                     ALHTAGRVSAAVVSVKGASLTEEEFSNLDLKTGF"
     gene            23661..25019
                     /locus_tag="ACZPCR_06915"
     CDS             23661..25019
                     /locus_tag="ACZPCR_06915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006780396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004180 - carboxypeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HIR1230644.1"
                     /translation="MERKQSGQPQTEEDIYRKISDMAEEQRDELIQLRRDFHRYPETS
                     WLEMRTSAKIAEYLTELGMEVLTGKDVCREEARIGVPDSDILERHFSQVKEQGAPARF
                     LTEELEQGYTGVVGILRCGEGPTVALRFDIDALPMEEAEDLEHRPFREGFSSQNPGMM
                     HACGHDCHAAIGLGTARILSELRDQLHGTVKFLFQPGEEGTKGAYAMVENGHLDGVDY
                     FAGTHVAPDDKEDDGDITPGTYGSLATCKYNVFFHGQAAHAGGFPEEGKNAVLAAAHA
                     AVGLSGIARHSQGISRVNVGVIRGGSNSNVVADEAMISMEVRGETDEINQYMDRRAKE
                     ICQAAAMMEECSCEMRLMGRAPSQVSSPELIDRISNLVRNHLPQYRVSSNPNAKNWGS
                     EDIGFMMNRVQEQGGQAVYMRTMTKMASPQHTVRFDVDEDVLVKGAVSFSAIVCDLLK
                     KN"
     gene            complement(25022..25243)
                     /locus_tag="ACZPCR_06920"
     CDS             complement(25022..25243)
                     /locus_tag="ACZPCR_06920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016438870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1230645.1"
                     /translation="MAIILRLDRVMADRKMSLNELSERVGVSNVNLSKIKTGKISAVR
                     FSTLNAICQALDCQPGDILEYIPDEDALK"
     gene            complement(25288..25779)
                     /locus_tag="ACZPCR_06925"
     CDS             complement(25288..25779)
                     /locus_tag="ACZPCR_06925"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230646.1"
                     /translation="MFLFLNAAFVLVDAAVFVSVLAVPGFYIEGNGWGIFLAQLLGGL
                     FIVQDGDGAHISYLALLLCAVSKILPNLITCYVFLALLRIFEKIKTGRTPFTELSSRM
                     WKNCSHIYAVLSVLAFLSSFIFGIAGLAALLPYMMTYLFFHALELIFLYGEGLQTESD
                     ETL"
     gene            26271..26516
                     /locus_tag="ACZPCR_06930"
     CDS             26271..26516
                     /locus_tag="ACZPCR_06930"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="polya polymerase"
                     /protein_id="HIR1230647.1"
                     /translation="MKIKMYHVSNLEKFMELVSQCKGNVYVVSEDGDKLNLKSKLTQF
                     VALSKLFASGYIESLSLETTDESDSALLLNYMISGEQ"
     gene            26616..27401
                     /locus_tag="ACZPCR_06935"
     CDS             26616..27401
                     /locus_tag="ACZPCR_06935"
                     /inference="COORDINATES: protein motif:HMM:NF025115.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HIR1230648.1"
                     /translation="MKKNYRLIACLSVSMLLFTGCASGQKPQETGAQTTAAPLDEEQN
                     VSERPSDKKENEKISIEVKEGQSYEKEEGTLSAKIRRPVLVDQNGTELSINKEISEYV
                     DSLIAEYEENKAASEKEEGDVHYAVSNTYEVTHDGEQYFSMYMAAARIMGSGSETYQT
                     YTIDKKTGEAVSLGELLGNEETLRLVSENISAQMEEQMKEDASVVYFQASEGGFSGLK
                     GDESFYLNQDGSLVVVFDEYTVAPGSMGMVEFTIPTETAGAFR"
     gene            complement(27411..28130)
                     /locus_tag="ACZPCR_06940"
     CDS             complement(27411..28130)
                     /locus_tag="ACZPCR_06940"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF012792.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1230649.1"
                     /translation="MDQTKRSTSEKAVKWLADRGIVNHIDMIEAIRIKQAEILYAEQD
                     GVMIYETDSQTCMIAAENFEPCRQILSQNTYHQFAVHQKELAEEIQAQYHFATSVLTN
                     QAAWMQKNAPEFDDSGIIALKNEHAKEVCSFYGTMEDPGDYVRELISRGQLWGIFEGD
                     RMAGFAGEHLEGSMGLLEILPEYRRKRYGFRLEAFLIRHFLEHGKIPFCQVIEGNTES
                     MSLQKKLGMEISEQPTWWLFN"
     gene            28495..28788
                     /locus_tag="ACZPCR_06945"
     CDS             28495..28788
                     /locus_tag="ACZPCR_06945"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230650.1"
                     /translation="MQIWPFGLPANGPIFRVDIQRMAVREDLMDVLTHEYGYFIHRHA
                     EADYVQKSKVFRAKELGGELMNGDWKYNINTRYSAKAKIDAAKISKYATAKSL"
     gene            28814..29146
                     /locus_tag="ACZPCR_06950"
     CDS             28814..29146
                     /locus_tag="ACZPCR_06950"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230651.1"
                     /translation="MDKGEKIPDNIEKVINAAKTKAGAKNVAKETGSGIMKNIRIPSA
                     ALSAKNITADIVDEIQSGIDGILLEYDAKIAFISVRDMSIQFPDTPYMIQSGDISQML
                     FRTFVIYP"
BASE COUNT         7932 a         6794 c         8064 g         6686 t
ORIGIN      
        1 gtatggatcc gtacctcaaa cggattctga atgggattca cgagggaacg ctggaggaag
       61 atcatcccta tgtgattaat cccaacggtg aaaaaagagg cgtctactat gaaaaaatgg
      121 acaacggatg gacctgcatt gtgacgattc catataagga actgttagga aacttttgga
      181 atgtaacgct ctggtatatg ggattattca atttctgctt tgccctggtg ctcttcatgg
      241 gggtgaacag ctgtctgctc agccgcaaaa tgaaacggat caacgagacg gttcaggttc
      301 ttggaaattc cttctacgca atctaccgtg tgaactttaa aaatgacgtt tatgatatga
      361 tcaagggttc ggaatatgtc cgttcccagg ttcctgaaaa gggacgctac agcgactttt
      421 tgaagatcat gggcggagtg atcgaggaac acgcctatca ggaatttatt gaaagctttt
      481 ctctctccaa tatcaaccat ctcgtttccc agaaggttca ggattacggc ggcgacttcc
      541 gaagacgctt tcaggacggc taccggtggg taagcattcg cttcctgtac gatgaatctc
      601 tcaataaaga cgaagctgtg ctctgtttcc gtgaagtgga tgaggagaaa aaaagccagc
      661 tgaagcacca gcatattctg gagacagctc tcgacagggc caaaaagaac gaggacgctc
      721 agaaccggtt cttctcagct atgtcccacg acatgaggac gcctctcagt gcgattatcg
      781 gaatgaccga gctggctgaa aagcaccctg aggacacggc acaggtaaaa agctatctga
      841 ggaggattgg cgtttccagc cgccagcttc tgggattaat caacgatatt ctggaaatgt
      901 cccgggtgca gaagggaaaa atcaccatcg aaaacagcga ttttgattta aaggccgcga
      961 ttggcgacta cacggccccc tttgccattc aggcggagag ggaaaacaag aaattcagcg
     1021 tttccttcca ggccagaaat catagagtgc ggggagacgc gttccgcctg ggacaggtca
     1081 tgaacaatct tttgtcaaac gcttttaaat ttacaaagcc aggcgactcg atttccgtct
     1141 gcatcaggca ggaggagctg tctgaagaca gattctgcat cgttgtctcc gacactggcg
     1201 ccggcatgtc ggaggaattt ctgacacgcc tgttccttcc ctatgagagg gaaaccaggt
     1261 ttggggcaaa atacattgcc ggaacaggcc tgggaatggc gattgtaaaa agtattgtca
     1321 gccagatgga cggacaaatt aaagtagaca gccgtctggg agagggcagc atgtttaccc
     1381 ttctgcttcc atttgaagtt ctacctgatg caaaggaaaa ggaacatacg gagacagctt
     1441 tggaaggctc tgaagcaaag gaaggttctg aacgggaata tacgaatctg tcgggactga
     1501 aaatcctgct ggcggaagac aatgaaatca acatggaaat ctgccgggag atgcttggca
     1561 tggcaggaat ccaggtgacg gaggcgtgga atggaagaga agccctggaa gccttccgtg
     1621 cctcttcagt ctcgcacttt gacgccgttt tgatggatat gcagatgccg gaaatggacg
     1681 gatgtgcggc agctatggca atccgaaacc ttaaaaatga gcgggaagac gcagagacga
     1741 ttcctatcat tgccatcacg gccaacgcct tcagcgagga tatcgcggcc acggaagcgg
     1801 cgggaatgaa cgcccatatc tccaagccta ttgattttcc tgtgctgtgc agaactctgg
     1861 aacggctgac tggaaacagg gtataactgt actctttaaa aaatgtattt ttgtccattt
     1921 aaacaggtac acttttgctg tatactggtc aaaacgcaga aaggagcgtg aatccagtga
     1981 aaaaaacagc agtgattcat gatttatctg gatttggaaa atgttctctc accgcggcaa
     2041 tcccgatcct ctcagtgatg ggagtccagg ccgttcccct gcccacagct gtattaagcg
     2101 gccagactgg atacggagac tatgtctgtg aagatttcac agcgcctatg tcctccatct
     2161 caaagctttg gaaaagacag gcagtagagt ttgacggcat ctattccggt tttctcctga
     2221 atgaaaggca ggcagaccag attttggagt ttatccggga tttttcgggg agggagactc
     2281 ttgttgtggt agatcccgtt ttgggggaca acggaaaacg atacgacatt tttgacagtc
     2341 agatggaact ggcggccgga cgcctggcag aacaggctca cgtaatcacg ccgaatctga
     2401 cggaagccct tctgttagga cggcaggcca gagaatcgat accagactgg aaggcggtcc
     2461 gtcttatggg acggcaggaa aggcttgcgc tggccgaaga cctggcggag gttctgacag
     2521 aatcctaccg gctgaggggc gcggttatca cgggaatcga actgtcacag aacgggttcc
     2581 cacagattgg aaatctggtc ctggcagaaa agggaacgcc gcagtggaca gtttctccca
     2641 aaacaggagg aagctattct ggaacaggag atatcctggc ttcgattgtc acggcctccc
     2701 tggtaaacgg cggctccctc tttgacagcg tctgcagggc ggcagatttt attgaaaaag
     2761 gcattcggga ggctgcgagg gaacaaaccg atcgaaacga cggaatctgt tttgagtcct
     2821 gtctctggga gcttggaagg gaggcgctgg gcagtgaaaa aagtctgtga cagagcttcc
     2881 gataaaaagc tggagcttat gtctcaggcc gctgtgatgg cggccctgac cgcagccctg
     2941 actctctggc tgcatattcc ggcaggatta aacggaggct atattcactt tggcgacgcg
     3001 gtgatttatc tggcggccgc gctgctgcca aagccttatg ccatggcggc gggagcggcg
     3061 ggcggcgtaa tcgccgatct tttgacagcg cctctgtggg cgccggccac cctgctgatc
     3121 aagccgcttc tcgtccttcc cttttcaaac ggaggagagc ggatcgtgac cagaagaaat
     3181 acggcggctc ttgtgctggc gttttttctg tcggcatccg ggtactttct ggcagaagga
     3241 ctgatgtttg gttttcacac ggcgtttctt gtctctgtct cgggcagcgc agtacagtcc
     3301 ggcgggagcg cgctggcatt cctggcagca ggaggcgctc tggatcgtct gcaggtaaag
     3361 aagagatgga gagccggttc gcgagggtga gaacgcggca aaggttaagg aggaaacggt
     3421 tatggcagat attgtgtacc aatacaaaaa ccaggtctat ttaaacatta cgaaccgctg
     3481 tccctgcaga tgtgaattct gtatcagaag ccacggcgat tccgtagggg atgcagaaaa
     3541 cctctggttt gagagagagc ctgaactgga agaaattttt gacgcagtcg acagcttcga
     3601 tttttccggc tgccgggaga ttatttactg cggctatgga gagccggtga tggctctcga
     3661 caagatgaag caaatcagcc ccttcctgcg ggaacggttt cctgactgcc gcatccgcct
     3721 gaacacaaac ggattgggcg atttgattta tggacggtct acagccggag aggtctgccg
     3781 tctggcagac agcatttcca tcagcctgaa tatgcctgac gccgacagct atgaggctgt
     3841 ggtccatcct gtttatggaa aaaaagcgtt tgcctccatg ctgcagtttg cccgggactg
     3901 taaagcgatt ttgggtgacg tccgctttac cgtagtggac ataatcggca gagaaaaggt
     3961 agaggaaagc cggcgcctgg cacagcgttt gggaattcct ctgagagtgc gggaatattc
     4021 ggaataaaga ctttgttaaa aatatataaa aaaagaataa agtttctatt gacttatagg
     4081 taatgatttg gtaagatcaa aagcaagaaa taaataagct atggattgtt actggtaagc
     4141 aggcaaaacc aattttgagg gagaagggta taagtgttcg ttcaggacag gatccttatc
     4201 ttcaaagttg gtttttttat tgccgcagta tcgtttgcca gagggagaac atgacttatg
     4261 agagtaaaca aggtgatcaa caataatatc gtaagcgctc tggattcgga gggaaaagag
     4321 attgttgtca tgggaagagg acttggcttc ggagcaaagc ctggaaagga aattcctgaa
     4381 gcgaagattg aaaaaatatt ccgtctggac agccagaaca ccatggaccg ttttaaagag
     4441 ctgctttcca atcttcctct ggagcacatt caggtctccg ctgaaattat caactatgcc
     4501 aagagcgtgt taaacagaag cctgaatcag aacatctatg taactttgac ggaccatatt
     4561 aattttgcca ttgagcggtt tcggaagcag atgcgttttt ccaatccgct gctcagtgag
     4621 attaaggctt tctacaagga agaatatctg ataggagaat atgccgttgc gttgattgaa
     4681 aaggaaatcg gcatctggct tccgatagac gaggccggct tcattgccct ccatgtggtg
     4741 acagctgaat acaatacagc catgagggaa accatcgaca ttacgaatct gattcaaaac
     4801 gtagttggaa tggtccggga ttattttcat gtgggcttag acgaaacttc tctcaattat
     4861 cagcggtttg tcacccacct gcgtttcctg gcccagcgga ttgtggcggg ggagctttta
     4921 gacggaggaa atcccgagtt taaccgcctg atttcccaga tgtatccgga ggaatacgcc
     4981 tgcagcctga aaatcaggga acacataaaa tcggtataca gccatgatgt gacggatgag
     5041 gaaaccgcat atctggcagt tcatataaaa cgtatcagag attaagaaag agaggaaaat
     5101 cgcatgtttt catcactgaa aaagatgttt ggaggaaaag aggagaaaaa gactgtttta
     5161 gctccagcag caggaaaggc cgtttcttta aaagaggtaa atgatccgac cttcagccag
     5221 gaaattcttg gaaagggcgt tgccattatc ccgtctgagg gaaaaatcgt ggctccggca
     5281 gacggaacca tcagcgtgtt ctttgagaca aagcacgcag tcagcatttc cgctgagaac
     5341 ggcgctgaga tcatcgtcca tgtaggcctt gacaccgtta atttaaaggg cgagcacttt
     5401 acagcccaca aacagcaggg cgacaaggta aaggcaggcg agcttctgtt agaattcgat
     5461 atggaagcga ttaaagcagc cggatacgat gttatcacac cggtcatcat ctgcaatact
     5521 ccagattttc cggatatggt ctgccataca ggccaggatg ttaaggaatt agatactatc
     5581 atcgagctgt agaaaggcag aaaatatgaa aattctgacg attgccgttc aaacggcaga
     5641 ggggcttcat gtaaagcctg cgtcccagct gtttatggcc gcgagagatt tcagctgccg
     5701 gattaccgct tcctgccggg aagcgcaggc ggactgtaaa agtatcctgg agctgttagg
     5761 cctgggggct gcgggaggag aacggcttgt tctaagcttt gacgggccgg atgaggaggc
     5821 agcagaacgc gccttccgcc gcctgacgga aaagtctgag gaattctcat acatctagca
     5881 cagcaaaata cgatttgcac ctgtcttctc aggcaggttc agataaaaaa actgccggta
     5941 gtccggcaaa aaaggaaagg ggttcattat ttatggtaat gaagttttta cagaaactgg
     6001 gaaaatccct gatgctcccg gttgcatgtc tccctgtctg cggtatcctg atgggaattg
     6061 gatatgcgtt atgtccaagc accatgcagg gcggtactgt agagggactg aaggagatca
     6121 tcggtttctt cctggtgaag gccggcggcg ctctgattga caacatgtcc tggctgttcg
     6181 cagtaggcgt tgcagtggga atgtccgacg acaacgacgg tacggcaggc cttgcaggtc
     6241 tcgtatcctg gttaatgatg acaaagctgt taaacccggc tgttgtaggt accttaacag
     6301 gcgttgctgc agatgcagta gacttatcct acagcaagat cgagacacag tttatcggta
     6361 tcctggcagg tatcatcggc gctatgtgct acaaccgctt taagactgcc aagcttccgg
     6421 actggctgtc cttcttctcc ggcaaacgct gcgttgccat cgtaaccgct ctggtttcca
     6481 tcgttgtggc agctgttctg ttcttcgtat ggccaatcgt gttcggcgca ttagttgctc
     6541 ttggaaaggg tatcatgagc cttgatgcag taggcgcagg tatctatgcg ttcttcaacc
     6601 gtctgctgat tccgtttggt ctccaccatg cgttaaacaa cgtattctgg ttcgacacaa
     6661 ttggtatcgg cgacctgaca catttctggg caggcgagac atctgcagat gttacatgga
     6721 gccttggtat gtacatggca ggcttcttcc catgtatgat gttcggtatt cctggcgctg
     6781 ccctggctat ggttcagtgc gctaagaagg agaagagaaa aattgtaatc ggtctcgtag
     6841 gttccgccgc tgtggctgct tttgtctgtg gcgttacaga gccgttcgag ttcgcattca
     6901 tgttccttgc tcctgttctc tacttagtat actcactgtt atacggtatt ttcacaacta
     6961 ttacagttgc ccttggtttc cgtgcaggct tctcattctc tgccggactg acagaccttg
     7021 tgttctccgc acagcttccg gctgctgcca agaccatgtt aatcatcccg ttaggcgctg
     7081 cagcattcgt tgtattctac ctggtattcc gtgttcttat cactaagtta gacttaaaga
     7141 caccaggacg cgaggacgac gatacagaga gcgagaaggc cgtaagcctc tccaacaata
     7201 actatacaga ggtagcctcc attatccttg agggacttgg cggcccatcc aatgtaactt
     7261 ccatcgacaa ctgcatcaca cgtctccgtc tggaggtaaa ggatcaggct ctcgtagatg
     7321 agaagaagat caaatccgca ggtattgccg gcattatccg cccaggcaag acaagcgtgc
     7381 aggttatcgt aggaactcag gttcagttcg tagccgacga gttcaagaag ctctgcaaat
     7441 aatacgttta caacggtatg aaaaagctcc tttatggagc tttttcgcat ttacggaaac
     7501 tggaagcttg cattttcaga ggcctgaaat tataatgaaa caagtgtaaa acacaatccc
     7561 tgacaaacga aggagaatgc aaatgatttt agccattgac gtaggaaata caaatattgt
     7621 gattgggtgt attgataagg aaaaatgcca ttttatcgag cggctctcca ccgtccggat
     7681 taagacagag ctggagtacg ccattgatat taaaagcgtg ctggatattt accatgtctg
     7741 ccccgaggag attgagggag gcattatttc ttctgtggtt ccccagatta ctacaaatat
     7801 taagctggcg gcagaaaaga ttctgaaaaa ggaaattctt gtgatcggtt ccggcattaa
     7861 aacaggactg gatatccgaa tcgacgatcc gggccagctg ggcgccgacc tggtggcggc
     7921 ttctgtggcc ggaattgcag aatatccagt tccgatgatg atctttgaca tgggaactgc
     7981 caacacagtc tgcgtcattg accgtgaaaa gcggtacctg ggcggcatga tctatccggg
     8041 tctcggcgta tccttagatt ccctgactgc ccacgcgtcc cagctgggag gaatcagcct
     8101 ggaagcccct gaaagggtga ttgggcgcaa tacaatcgac tgcatgaaga gcggcgtgat
     8161 ttacagcgcg gctgctgcca tggacggcat catcgacagg attcaggagg aaatgggaga
     8221 gacgctgaca gttatcgcta ccggaggtct ggccaaatgt atcgtgccgc actgcagaag
     8281 agaagtgatt ttagacgacg atcttctgtt gaagggactt ctggttctct acgataaaaa
     8341 cagacggtaa acgttatggg agctttatct gaaaaccagc tgaaaaaaca tatctgcgcg
     8401 ggaattgtag cccatgtcga cgccggaaaa actacgctgt cggaggccct tttatatctg
     8461 tccggttcta tcagaaagct gggccgtgta gacaatcagg acgctttcct ggatacctgc
     8521 cagctggagc gggccagagg aatcactatt ttttccaagc aggcggagct tcagtggaac
     8581 ggtacgtccg tgacgctgtt agacacaccg ggacatgtgg atttttcggc ggagatggaa
     8641 cgcacgcttc aggtactgga ttatgccatt ctggtaatca gcggcgccga cggcgtccag
     8701 ggccacacgg aaaccctgtg gcgtctcttg gccagatatg aaatccctgt ttttttgttt
     8761 atcaacaaga tggatcagcc tggaacagac agagacgctt tgatgagaga gctgaaaaag
     8821 cgcctggatg agggctgtat cgactttcag gaggagggga cagaagagtt ttatgagcag
     8881 gccgccatgt gcgaggagaa gcttctggac gcctatctgg aaacgggaac cgtggaggag
     8941 gaggaaatcc gccgcttgat ccagaaaagg aagcttttcc cctgcttttt cggatctgcc
     9001 ttaaagctgc agggagtgaa agagctgttg gacggtttct gccgcctgtc taagcttccc
     9061 tgctatcctg aggactttgg agccagaatc tacaagattt ccagagacgg ccagggaaac
     9121 cggctgagtc atctgaaggt gacaggcgga atcctgaaag taaaaacagc tcctgtttcc
     9181 ggctgtcccg ataaaattaa tcaaatccgc atctactccg gaagccggtt tgagacggtg
     9241 caggaagcgc cagccggaac cgtctgcgcg gtatccggtc tttcttcgag ctttgccggg
     9301 cagggactgg gatttgagga ggagcttgcg gcgccggttc tggaaccggt gctgacctac
     9361 cgcctgatcc ttccggaggg ctgcgatgcg gcgtcctttc tcccgaagct cagacagctg
     9421 gaagaagaag aaccgcttct gcgggtactg tggaatgagt ctctccagga gatttccatg
     9481 cagatgatgg ggcaggtgca gattgaggtg ttgaaaagcc agatggaaga gcgcttcggc
     9541 gttttggcgg agttcggcac cggttccatt gtatataagg agaccatcgc ggggccggtg
     9601 gagggggcgg gacattttga gcctttgcgc cactatgcgg aggtccacct tctcctggag
     9661 ccgggagaac cggggagtgg tctttccttt ggcagtctgt gcagtgagga cgttctggat
     9721 aaaaactggc agcgtcttgt gttcactcat ctggaagaga ggcagcatcc aggcgttctc
     9781 acaggctctc ccattaccga tatgcgcatt ttactgacag caggaagagc ccatcccaag
     9841 cacacggagg gaggagattt caggcaggcc gtctgcagag cgcttcgcca ggggctgatg
     9901 gaggcggaat cgctcctgct ggagccctgg tattcctacc gcctggaggt gccggagccg
     9961 tctatcggcc gggctatgaa cgatatggaa cagcgaagcg gaacctgcgt cttagaagag
    10021 tccagggacg gcatggctgt tttgaccggg caggcgcctg ccatctgtct gacagagtat
    10081 caggcagagg ttacctctta ctccagggga cggggacgcc ttttctgctc tctgcttgga
    10141 taccggccct gccacaacac agaggaggtc ataacccgta tcggctacga tccggaacgc
    10201 gatacagaca atcccacagg atccgttttc tgcgcccatg gagcaggatt tgccgtcccc
    10261 tggaatcagg ccaaggcgta tatgcatgtg gagagcggcc tgcatctgga ccgcgaagat
    10321 gagaaacagg acggacagcc caggggcttt aaaaatccag gttccagcac aagacaggaa
    10381 gcggccgagg agatgtggat gggtacggag gaaatcgacg ctatccttga gagaaccttt
    10441 tattccaaca gccgcggaaa ggatacgccc aggaaaaaat actcctccgg cgtcagaaaa
    10501 cagcgccgct tcccggaaga accgtcgtct cagccgatcc gatccgccct gaagccagcc
    10561 ggaaaaaagc aggaatatct gctggtagac ggctataacg tgatctttgc ctgggagagg
    10621 ctgaaggctt tggcagagga caatctggac ggagccagaa tggcgctcct ggacatgctc
    10681 tgcaattatc aggcggtccg ccagtgctct cttatggtcg tattcgacgc ttaccgggtg
    10741 gagggccata cgacagaggt cagcgcctac cacaatattc aggtggtgtt taccagagag
    10801 gcagaaacgg cggatcagta tattgaaaaa ttcgcccacg aaaacgccgg ccgcttcgac
    10861 gtgtcggtgg ccacctccga cggggtggaa caggttatca ttctgggcca gggatgccgt
    10921 ctcatctctt ccagagagct ggaacaggaa cttgagcgga tgaatcaggc ccttcgggag
    10981 gagtttttgc tggagacgga aaaaaagggc atccgtctgt cagatcttct gacagaggag
    11041 gagcttttaa ggctcaggca ggaaatagag ccggagacag aataaaaaca aggagtgtgt
    11101 tatggcagat attcattgga ttaccgattt ttcagctcct gagctggata tttacgccag
    11161 gctttcagag gggcagctgc tccattacca tgagccggac acaggaatct ttattgcaga
    11221 aagtcccaag gtcattgagc gggccttgga cgcaggctat gaaccagttt cctttctcac
    11281 agatccaaag tgtatggagg gggaggcgaa ggatatttta gcccggtgta cggggattcc
    11341 cgtctatgca gccaaattcg atatccttac aaaattaaca ggatttcagc tgaccagagg
    11401 cctcctctgc gccatgcgcc ggaaggctct tccagacgtc aaaagcctct gtgccggcct
    11461 tacgcggatc gtaattctgg aaaatgtgat gaatcccacc aacgtagggg cggtattccg
    11521 ctcagccgcc gccatgaaca tggacgcagt tcttttaacg cccggctgca gcaatcctct
    11581 ctaccggaga gccagccgtg tcagcatggg aaccgtgttc cagattccct ggaccttttt
    11641 tgacgaaaag aaaggcgcct ggccagaagg cggaatgaaa atcctgaaag aactggggtt
    11701 taagacggct gccatggctc tcagagagga ttctaccact cttgacgatc cggcgctgaa
    11761 agcggaggaa aagctggcgg tgatcatcgg aacggaaggc gacgggctgg cctcagagac
    11821 catcgcagac tgcgactaca cggtgcggat caagatggcc agaaacgtgg attctctcaa
    11881 cgccgcctct gcggcctgcc tggcgttctg ggagcttggg aagcgtctct aaggcggaaa
    11941 actgaagctg ccatcctgtt tgtaaagcca aaaacagatt gatttctcat aaaatctcta
    12001 gtatagtaat tacaggttta aaagggaaag aaggaaaaag agatgatacg aatagcagta
    12061 gacgccatgg gcggagataa cgctccggaa gagctggtgg cgggagccgt ggaagcggta
    12121 aaggaaaaaa gcgaaatcaa ggttcttctg attggacagg aggacgctgt aaatcgtgag
    12181 ctttccaaat atacatataa taaggaacag attgaggtcg ttcacgccag cgaggtgatt
    12241 gccacagagg agccgcctgt caacgcggtg cgcaaaaaga aggattcctc ccttgtggtg
    12301 ggcatgaaca tggtcaggaa gggggaggcg gacgctattg tgtcagccgg aagcaccggg
    12361 gctatcctgg taggaggcca ggtgctggta ggccgcatca agggtgtgga gcgtccgccg
    12421 ttagccgttc tgattcccac cgataagggg gtatctctcc ttctggacgg aggcgccaac
    12481 gtggacgccc gcccgtccca tctggtacag ttcgccaaaa tgggttccat ctacatggag
    12541 catgcgatgg gagtcaaaca tccgcgggta gccattgtca acatcggcgc ggaggaggag
    12601 aagggcaacg ctctggtcaa ggagacgttc ccgcttctga aagagtgcgg cgatattaac
    12661 tttaccggca gcattgaggc ccgtgagatt ccccatggag gcgcggacgt tatcgtggcg
    12721 gaggccttcg tgggcaacgt cattttgaag ctgtacgagg gcgtgggggc cgccctgatt
    12781 tccaaggtga aagagggcat gatgacaagc ctccgatcca agataggcgc gcttcttgta
    12841 aagcctgctt taaagacaac cttaaaaagc tttgacgcca gccgctatgg cggagcgccg
    12901 cttctgggct taaagggcct ggttgtgaaa acccacggaa gttccaaacg gacagaggta
    12961 aagaattcga ttattcagtg tcttactttt accgagcagg gcgtcaatgc aaaaattcag
    13021 gaaagtctga gggagaaaga aaacagagag gcaggtctca gcgatggaat ttgaaaaact
    13081 gcagaaaatc attgcagagg tgttaaatgt ggagcctgag gagattgcca tggaaaccac
    13141 attcgtggat gatctgggcg cagactccct ggatattttt cagattgtaa tgggaattga
    13201 agagggattt gacattgaaa ttcccacaga ggcagccgag cggattgtga cagtgggaga
    13261 cgcggcagag caaatcaaga atgcgttaaa ttaatgctct gataccaggc gcgcaacgag
    13321 cggcaatccg gtatcagagg gggatctttt cccgaacatt ataccatttc agcagggagg
    13381 cagctctggg aacagggctg cttccagcat atcatgaaca gtcaggagga tctatatgac
    13441 acatgcacat ttaaacgagc ttcagggaaa gattggctac tcctttaagg acagctctct
    13501 tctcaccctg gccatgagcc acagctccta cgccaatgaa aagcacctga gtaagctggg
    13561 ctgcaacgaa cggctggaat ttttaggaga cgcagtgctg gagattgtgt ccagcgactt
    13621 tctttttcac cggtttcccg atatgccgga gggggatttg acgaaaacaa gggccagcat
    13681 ggtgtgcgag ccgacgttag cctactgtgc ggagcagatc gatctgggca gctatctcct
    13741 tttgggaaag ggggaggacg ctaccggcgg acgtaccaga aattccgttg tctcagacgc
    13801 catggaggct ctgatcggag caatttacct ggacggtggt tttactagcg caaaagagtt
    13861 tattctgaat tttgtcttaa atgatatgga acacaaaaaa ctcttttatg atagcaagac
    13921 tatcttgcag gagatcgtgc aggccagagg cacggagctt ttatcctacg aacttctgga
    13981 ggaaacgggg ccggatcaca acaagacgtt ccaggtggcg gccttgatcg gaagccagga
    14041 aatcagccgc ggctttggac ggacgaaaaa agcggcagag cagagagccg cttatcaggc
    14101 gattctgaag ctgaaagcag aagaaaataa aggcgtttag gtgatctatg tatttaaaaa
    14161 gcattgaaat tcagggattt aagtcctttg ccaacaagat tctcttcgag ttccacaatg
    14221 gtatcaccgg catcgtcggc cccaatggca gcggaaagag caacgtggcc gatgcggtcc
    14281 gctgggtgtt aggagagcag agagtccggc agctgcgggg cggaaccatg caggacgtta
    14341 ttttctcagg tactgagata cgaaagcccc agggatttgc ctatgtggcc attacgctgg
    14401 acaattcgga tcacaaactt cccatcgcct acgatcaggt aacagtttcc agacggcttt
    14461 accgttccgg cgagagcgag tacaaaatca atggaagcgc ctgccgcttg aaagatatca
    14521 acgaactgtt ctatgacaca ggaattggaa aggaaggcta ttccattatc ggacagggcc
    14581 agattgacaa aattttaagc ggccggccag aggagcgcag agagctgttt gacgaggcgg
    14641 ccggaatcgt aaaatttaaa aagcgcaagc tgatcgccca gagaaagtta gacgacgagg
    14701 agcagaacct ggtgcgcgtc aaagacattc tgtctgagct ggaaaagcag gtaggcccgt
    14761 tgaagcttca gtcagaggct gcgaaggaat acctgaagct gaaagaggag ttaaagggca
    14821 gagacgccaa tctctttctg ctggagcaca aagcgctgca gctgcagctc tctgagctgg
    14881 atcagaagac ttctatcgta aaaggagact gggagaacgc ctccagccag tcagaacagc
    14941 tgaaaaagga ttttgacagg ctggaggagg agaattctgc ctctgaagaa aaaattgcct
    15001 ccaccaggga ggaacactcg aaatccatcc ttttaaagga gagcatagag gggcagatcg
    15061 cagtcctcag ggagcagatc cgttccgagc agctgaatga ggagaacagg aaggagcgga
    15121 tttcctccat tgatcaggag cttctgggaa aagaggaaca aaagcaggag tacgagaagc
    15181 agagggagga gacaaaaaag caggtagccc aggcagaaca ggctcttacc caggcaggac
    15241 agactctctc agagacagag caggagatgg caaggctctc aaaagagtcc gaagcggcta
    15301 aggcggcaat tatctctgct ctcaacgaga aggccggtct ggctgccaaa agccagcggt
    15361 acgaaaccat gttagagcag gtggacgtgc gccgctcaga ggtaacgcag aagcttctgc
    15421 gctttaaaag cgacgaatcc gtgcaggagg aggagctgaa aaaagaggag aagcgtttag
    15481 agcagataca ggaggagctg gacaggctga cggagctgga agaggaaacg gcgtttcgtc
    15541 tgactgccgc agaggaggat ggagccgctc tggccgcccg gttaagcaga agccagcagg
    15601 attaccatat cagccattcg aaactggaat ccttgaaaaa tctggcggag cggtacgaag
    15661 gatacggaaa cagcatccgc cgggtgatgg aacaaaagag ccggattccc ggaatccacg
    15721 gcgtggtggc ggatctgatc tccacatcga aaaaatatga gacagccatt gagacggctc
    15781 tgggaggcag tatccagaac attgtcacag accgggagga gacggccaag gagctgatcg
    15841 aatatctgaa gaaaaacaga tatggccggg ctaccttcct tccgcttacc ggcatcagcg
    15901 ccagaggcgg ctttactcag gaaagcgctc tgagagagcc tggaattctg ggactggcca
    15961 gcgatctggt ggaggtgaag gacgagtaca gaaccctgat ccagtacctg ctggggcggg
    16021 tggtagtggc ggataccatc gaccatgcca tcgccctggc cagaaaattc cgccatactc
    16081 tccgaattgt caccctggag ggagagcttt taagcgcagg cggttccatg acaggaggat
    16141 cctttaagaa cagcagcaac ctcctgggac gccagagaga actttctgag cttcaggcat
    16201 cctgccggaa ggccttgcag gatgtggaag agacccagaa ggcaatcgca gataacggcc
    16261 gcctgaaagc ccaatgcgcc ggagaggcgg cgaggcttcg ggagacaaag caggagattg
    16321 ttctgagaaa aaatacggcg cagatgaata tggaacggct tctgggaaag aagcaggaga
    16381 tagcggaatc ctccgccgac ctggtgatgg aaaacaggga gctggagttc cagctcaagg
    16441 aaatccggga aaacagggcg cgtctgtcca gagaagaaga acagctggag cagctccaaa
    16501 aggagcagga ggcacgctcc gaacagcttt ccagaaagct ctctgatgct cagcagcaga
    16561 aggaggagac ggcaaagctt ctctccggcg cacagctgac ggcggctgga atccgtcagc
    16621 aggaccgctt tattgcagag aatgtaagcc gtattttaaa agaagagagc agcctgaaag
    16681 aagaacggca gcggattctc gacggcagca gcgaaagcga ggcagtgatt tcagaaaagc
    16741 ttgctaagat tgaacagctt ggccgccaga ttctggagga gacgtcgaag gctcagagac
    16801 tggaggaagc gctggcccag aattcagaag aaaaggaacg tctggctgaa aaacagaaat
    16861 cctttttccg gaagagggag gagctttccg aggaaattgg ccgtctggac aaagagctgt
    16921 accgtctgga gagccagaag gaacggctga cagagcggat gagcgatcag atctcctaca
    16981 tgtgggagga atatgaactg acctattccg gcgcccaggc tctgaaggac gaagcgccgg
    17041 gaaccattcc tgagatccgc cgggccatcg aggaactcaa aggaaacatt aagggacttg
    17101 gaaacgtcaa tgtcaacgcc attgaggact accgggaaat ctccgaacgg tacgaattcc
    17161 tgaaatctca gaacgacgat ctagcggcag ccagggaggc tcttttaaaa attatagaag
    17221 agctggatac tggcatgcgt cttcagtttg aagaaaaatt cgcccagatc cgccaggaat
    17281 ttgataaggt gttcaaggaa ctgttcggcg gcggccacgg cgctctgatt ctgcaggaag
    17341 atgaggatat cctggaggcg ggaattcaga ttatttcaca gcctccggga aagaagcttc
    17401 aaaatatgat gcagctgtca ggaggagaga aggcgctgac cgcaatcgcc cttctgttcg
    17461 ccatccagaa cctgaaaccg tcgcccttct gtcttctgga cgagattgag gcggcattag
    17521 acgattccaa cgtagaccgg tttgcaaaat atcttcacaa gctgacaaaa aatacacagt
    17581 ttatcgtaat tacccaccga agaggaacca tggtgtcctc tgaccgcctg tacggtatca
    17641 ccatgcagga gaagggcgtt tcgactctcg tttccgtaaa tcttgtggag agcgagctgg
    17701 aagcccaggc aaaggcaggc aggacaaaat tttagacaga cttttatata gaggaggaaa
    17761 gcatacatga gcggaggaaa aaaggggttt ttcggacgcc tggtagaagg gctgacgaag
    17821 acaaggaatt caattgtagc tggaattgac tcaattttca gcggtttttc agccattgac
    17881 gacgatttct acgaggagat tgaggagacg ctgattatgg gagacctggg aatccagact
    17941 accatggcga ttatggagga tctccgccag aaggtaaagg atcagcacat caaggagccg
    18001 tccgagtgca aggagcttct gattgagagc atccgttctc agatggatct gggcgaaaat
    18061 gcctatgaat ttgaaaacag gaaatctgtg gtccttgtca tcggagtcaa cggggtggga
    18121 aaaaccacct cagtgggaaa gctggcgggc cagttaaagg atcagggcaa aaaggtgatt
    18181 ctggcagcgg ccgacacctt ccgtgcggcg gccatcgagc agctgaccga gtggtccagc
    18241 cgtgcgggtg tggagctgat tgcccagcag gaaggatccg atccggcagc cgtcatctat
    18301 gacgccatcg cggcagccaa gtcaagacac gcagatattc tgatctgcga tacggcgggc
    18361 cgtctccaca ataaaaagaa cctgatggag gaattaaaaa agatcaaccg aatcattgac
    18421 aaggagtatc cggacgcata cagagagact ctggtcgtgc tggacggaac caccggacaa
    18481 aacgccctgt cccaggcgaa gcagttcatg gaagccgccg atattaccgg aatcatcctg
    18541 acaaagctgg acggaaccgc caagggagga atcgccgtag ccatccagtc ggagcttggc
    18601 attccggtga aatatattgg aattggagaa aaaatcgagg atcttcagaa atttaatgca
    18661 aatgactttg taaacgccct gtttgagaag ccggcagaac agtaaaaaaa cagaagagga
    18721 gagggaacgt tatgtgcgaa aacgaaaaga agcttacact ggaaaaattt gaggaagcca
    18781 ccgaggtggt aggaaaggtg atttctgaga caaagttagt ctacagcgaa cacttttcca
    18841 atatgacggg aaataaggtc tattttaaac cggaaaatat gcagtacacc ggcgcttaca
    18901 aggtaagagg cgcttactac aaaatcagca ctctgtcaga ggaggaaaag cagaaaggac
    18961 tgattactgc ctccgccgga aaccacgcac agggagtcgc ctatgcggcc aagctggccg
    19021 gcattaaggc cacgattgtc atgcctacct ccacaccgct gatgaaggtc aaccgcacca
    19081 gaggctacgg cgctgaagta gtgctggaag gagacgtgtt cgatcaggcc ctggcccatg
    19141 cctaccagct ggcagacgag cacggataca ccttcgtcca tcccttcaac gatctggacg
    19201 tggccacagg acagggaacg atcgccatgg agattatcaa agagcttccg acggtggact
    19261 atattttagt tcctatcggc ggcggcggcc tctgtaccgg agtgtccact ctggccaagc
    19321 tgttaaatcc caagatcaag gtaatcggag tggaaccggc cggagcaaac tgtatgcagg
    19381 aatccttaaa ggctggaaaa gtagtggctc tcccaggcgt caataccatt gcggacggaa
    19441 cagccgttca gaggcctggc gatcttttgt tcccatacat tcaggaaaat gtggataaaa
    19501 ttattaccat cgacgattcc gagctgattg tggccttcct ggacatggtg gaaaatcaca
    19561 agatgattgt agaaaactcc ggtcttttga cagtagccgc cttaaagcat ctggatgtga
    19621 agaaaaagaa aatcgtttct attttaagcg gcggaaatat ggacgtcatc acgatggctt
    19681 ccattgtcca gcatggactg atccagagag accgggtatt cacagtttcc gttctgcttc
    19741 cagacaagcc cggagagctg gccaaggtcg cttcacttct ggcagaacag cacggaaatg
    19801 tgatcaagct ggagcacaac cagttcgtca gcatcaaccg gaacgcggcg gtggaactgc
    19861 gcattaccct ggaagccttt ggaacggatc acaaaaatac aatcgtagcc gcgttaagcg
    19921 aggccggata ccgtcccaag cttgtcaagt caaagggcgt ctacgagctg tagatgaaat
    19981 ggggggagct gtaaaagcat tatgtatcaa ttagataaaa atacgcctct ggggaaaaat
    20041 ctctggtttt tcgtcaaatg gagcgctgtt tccactctga tcggtctgac caccggtctg
    20101 gtgggaactg tattcgggca tcttgtcatg agggcaggcg cttattttaa cagccgccgc
    20161 tggaccttag cccttctgcc ggcagccggc ctcatgattg tatggattta ccacctttta
    20221 aaagaagaca aaaacagagg aaccaacatg gtgattgaat ccatctacac ggattctgat
    20281 atttctcccg gcacagcgcc ggctattttc ctgggtacga ttctcactca tttctccggc
    20341 ggatctgccg gacgggaggg agccgccctg cagatgggag gaagcatcgg caaccagatt
    20401 ggccgcctga tgaagctgga cgagaaggat aaaaagattg cggttatgtg cggaatgagc
    20461 ggcgcctttg ccgctctgtt cggcaccccc atggctgcgg ctctcttttc catggaggtt
    20521 atcagcatcg gcgttatgta ctatgcggcc ctggttccct gcaccttttc cgcatttatt
    20581 ggagcggctg tttcaaagca cctgggactg gctccggagg ccttctccat cggcccggtt
    20641 cctgaatttt ctctgaaagc ggccctgatc atgactgtat taggcgtttt atgcgctctt
    20701 gtttcagagc tgttctgcat tgtccttcac cgcaccgaaa aggtgtatcg gaggtacttt
    20761 ccgtctccag gcaggcggat agcggcaggc gctgttctga ttatcatact tacgcttctg
    20821 gagagttcct ttgattacaa tggaagcggt attctgctga ttgagcggtg ctttgagggg
    20881 gacgtccggt acgaagcctt tctctggaaa atcctgttta ctgcagtaac tctggaggcc
    20941 ggttttaagg gaggagagat tgttccaacc ttctgtatcg gcgctgtctt tgggtgcagc
    21001 tttgccatga taacagggca gccgttcggc ctgatgacag cctgcggtat gctggctctg
    21061 tttgtgggag tgaccaactg tcctatttcc acgcttttga ttggcttcga gatgttcgga
    21121 taccaggcaa tgccctattt tgtgctggtg attgccgtga gttttactct ttccgggtat
    21181 tacagccttt actccagcca gaagtttgtc tactctaaga cgaaaacaga atatatcaac
    21241 cggaaaatgg aagagtagga ggaaagttca atgaaaacac tgattcggca cgcgactgtg
    21301 cttaccatgg acgagaaaaa tactgtattt aaaaacggct gcgttttaat tgacggggac
    21361 aggattgtaa aagcggggga ggaggaggag ctgcaggcag agatggagtc cttcggcgct
    21421 tcacagataa ttgacggcca cggaggaatc ctgattcccg gcctgatcaa cacccactgc
    21481 catgtctcca tgatgccctt ccgcaccctg ggagacgact gcgccgaccg cctgagacgt
    21541 tttctttttc ctctggaaaa tgacgccatg accagaaaat tagtccgcct ggccgccaga
    21601 tacggaatct gcgagatgct gttagccgga gtaacctcct ttgtggacat gtactatttt
    21661 gaagatcagg tagccgaggc ctgtgaggag cttggcatcc ggggctggct gggagagacg
    21721 gtgatcgggc agaaaacctg cgacagtgaa gagccctacg gcggcctggc ttatgctgag
    21781 aactttatca ggcagtggaa aggcagcaat cttgtaaaac cctctgcagc tccccacgca
    21841 acctacagca acagcccgga aatgctgaaa aaagcttacg agctgtcatg taagcacgac
    21901 accctgttta ccctccatgc cagcgagatg gactttgaga tggaacagtt ccggcgtgag
    21961 aagaacatga cgccgtctga atttttatac gatctgggcg tattaagcgg caggactctg
    22021 ctggcccact gtgtttacat gacggatcgc gacatggatc tgctggcgga gacggggaca
    22081 tctgtcgccc actgcattgg ctccaacaca aaggggggca gaggagtagc ccctgttcca
    22141 gccatgcaga agaggcagat tccagtagga tttggaacag acggcgcttc ctccggaaat
    22201 acactggatc tgtttaccct gtttaagctg tttgccgatt tccagaagac ggcttaccat
    22261 gacagaagcc tgttcccggc agaggacatt gtgagaattg gaaccatggg cggcgcgcag
    22321 gcgctccatg cagaaaagga tctgggatcc atcgaagctg gaaagaaagc agatttagtg
    22381 atcgtggaga cagattctgt caatatgttt ccatgttaca atccctattc tgcccttgtc
    22441 tactctgcca acgcctccaa tgtggacacg gttatggttg acggacagct gcttgtgaga
    22501 ggcagacagc tggtcaatgc cgacctggcc aagatccggg aagagcttcg ccaggaaatg
    22561 ggccccttta tggaggcggc cagacagtat ggagacatgc tgtagattaa aacccagtct
    22621 ttaaatcaag atttgaaaat tcttcttctg tgagggaggc tcctttcacg cttactaccg
    22681 cggctgaaac gcggccagcg gtgtgaagag cctctctcat gttatatcca aggcttaaac
    22741 aggccatgac cgttccaata tgggaatcgc ctgctcccac cgtatcggcg acctgggccg
    22801 ggtaagcggg aatctggtaa aaggatccgt ccttttccag gcagcaggcc ccgtcttttc
    22861 ctaacgtaac gatcactgta tttcctgtcc tatgagccag cgcttctgcc gcttcccttg
    22921 cctgactgca gccggagagg gcgcaggcct ctgcctcgtt gatatggaga accgggtgga
    22981 gcgcaagcat tctctctgtc ttttctcttt caatcagaat cccccttgga cccggggcat
    23041 aaaaaatctg ctgttccctg tgatcctcca gatagcctaa cagttcgttg cccgtaggct
    23101 cctccacctc cagcccgcag acataggtta tgtcaaaggt ctccttctca aagggttcca
    23161 tccatgttct gctgaacgta tactcggctc catgcaggga cataaaggtt ctctctccgc
    23221 cccgttctac cagacagtag cagcatccat tttcctgatc cgggacgtcg gccagcacgg
    23281 gaaccccctt ctgtttcagt tcttttctca cataatctcc gtaaacaccg gttcctaccg
    23341 gtgaaataaa ggtatggggt gctccaaact gtcggatgat gttagccgca ttgtaggcgc
    23401 acccgcccaa agccatggac tggctgaagg gatgaatgtc ctcctctgtc ttcggaagat
    23461 ggtctacatt gataataata tccacgcagg tggagccaat gatcaagatt tttttcgggg
    23521 tctggattct ggttttcata taatatttcc tcacattgaa attataattg aaagtcgctg
    23581 tttttatagt atactaaaaa acagaaatat tcaaatagtt tagacagcta taaatactga
    23641 ttttaaagga ggagacaacg gtggagagaa agcagagtgg acagccacag acagaagagg
    23701 atatctacag aaaaatttca gatatggcgg aggagcagag ggacgagctt atccagctcc
    23761 ggcgtgattt tcacagatat ccggaaacca gctggctgga aatgagaact tccgctaaaa
    23821 ttgcagaata tctgacagag cttggcatgg aagtcctcac cgggaaggac gtgtgcaggg
    23881 aggaagcccg tatcggcgtg cctgattcag atattctgga acgccatttc agccaagtga
    23941 aggagcaggg cgcacccgcc cggtttttga cggaggaact ggaacagggg tacacgggag
    24001 tggtaggaat cctccgctgc ggggaggggc cgaccgtcgc tctgagattt gatattgacg
    24061 cgctccccat ggaggaagca gaggatctgg agcatcgtcc tttccgggag ggattttctt
    24121 cccagaatcc aggaatgatg cacgcctgcg gccatgactg ccatgcagct atcggccttg
    24181 ggacagccag gattctatct gagctcagag atcagctgca cggcactgta aaatttctgt
    24241 tccagcctgg ggaggaaggg acaaagggcg cttacgccat ggtggaaaat ggccatctgg
    24301 atggagtcga ctattttgcc ggaactcatg tggcgccgga cgacaaggag gacgacgggg
    24361 atattacccc aggaacctac ggttcactgg ctacctgtaa gtataacgtc ttcttccacg
    24421 gtcaggcagc tcatgcagga ggctttccgg aagaagggaa aaatgccgtt ctggccgcag
    24481 ctcatgctgc agtagggctg tccggcattg cccgccacag ccagggcatc agccgcgtca
    24541 acgtaggagt gatccggggc ggcagcaaca gcaacgtagt ggcggatgaa gccatgattt
    24601 ccatggaggt ccggggagaa acagatgaaa ttaatcaata catggatcgg cgggcaaagg
    24661 aaatctgtca ggcagcagca atgatggagg aatgcagctg cgagatgcgg ctgatgggca
    24721 gagccccctc ccaggtcagc agtccggagc tgatagatcg gatttcaaac ctggtcagga
    24781 accatctgcc ccagtaccgg gtgagcagta atccaaacgc caaaaactgg ggcagcgaag
    24841 atatcggttt tatgatgaac cgggtacagg aacagggcgg acaggctgtc tacatgagaa
    24901 ccatgacaaa aatggcatcc cctcagcata ctgtgcggtt tgatgtggat gaggatgttc
    24961 ttgtaaaggg agctgtttca ttttctgcca ttgtgtgcga cctgctgaaa aagaattaaa
    25021 atcattttag agcatcttca tctggaatat actctaaaat gtcccctggc tggcagtcta
    25081 aggcctggca gatggcgttc agggtgctaa aacggactgc gctgattttt cctgttttaa
    25141 tcttggaaag atttacatta gaaacgccta cccgctctga caattcatta agcgacattt
    25201 ttctgtcagc cattacccgg tcaaggcgga gaataatagc cataaaaaag actcctttca
    25261 taagataggc gcgggtaaaa tccgcgccta caaagtttca tctgactctg tctgcagccc
    25321 ctctccatag agaaaaatca gctctagcgc gtggaaaaac aggtatgtca tcatgtaagg
    25381 cagaagggct gccagtcctg ctattccgaa aataaaactg cttaaaaaag ccaaaacaga
    25441 taaaacagca tagatgtgag agcagttttt ccacatgcgg gagctaagct ccgtaaaagg
    25501 agtccttcct gtcttgatct tttcaaatat acgcagaaga gccaggaaca catagcaggt
    25561 tatcaggttg ggaagtattt tagacactgc gcagagaagc aatgccagat aactaatatg
    25621 ggcaccgtcc ccgtcctgca caataaacag gccacccaaa agctgtgcca aaaagattcc
    25681 ccagccgttt ccttcaatgt aaaaccctgg aactgccaat acgctcacaa atactgccgc
    25741 atccaccaga acaaaagctg cattcagaaa aagaaacacc tttaaataag agcaaataag
    25801 tccgctttcc tctgaaagca gattcaagag agacgattgg ctaagatttt ttaagttttc
    25861 acgcttcata tggttcgctc ctttctaaaa ctcatcagca gatgatgccc tgctttctct
    25921 aacagttatc tttctgtttt aattatacct cttattttta tggaatgcaa taatttttta
    25981 atgtttatca ttaaaaatgt ttaacgtata tggaagcagg gatatggaag tataggctga
    26041 acagcaagac aaaatagaaa cactcaggtt ttattaaaac gtattctacc cgctcgtcgt
    26101 tatggataat tcttctgcat tttcttccat atttctgtcg aaagaggaga atctggaaaa
    26161 agaagagacc ttctatttga caggagacgt cctgtgtctt atcctaatag cgtaaatata
    26221 agttcagaat cagataactg gcagtccaga aaaaggagga accatatttt atgaagatta
    26281 aaatgtacca cgtaagcaac ctggaaaaat ttatggagtt agtcagccag tgtaagggaa
    26341 acgtatatgt cgtttcagaa gacggagaca aattaaatct aaaaagtaag ctgactcaat
    26401 tcgtagctct gtccaagctg tttgcttccg gatatatcga gagcctttct cttgagacaa
    26461 cagacgaatc agactcagct ctgctgttaa actatatgat cagcggcgag cagtagaaga
    26521 ggagcgcaga aactgcaaaa agtttttctg cgctccaact ttttacccat ccctcccatc
    26581 tataaaacag aaagaaaaca aaaggagaga tgattatgaa gaaaaattat cgattaatag
    26641 cctgtttatc cgtatccatg ctgcttttta ccggctgcgc ttccggacag aagccgcagg
    26701 aaaccggtgc tcagaccaca gcggctccgc ttgacgaaga gcagaatgtt tcagaacgtc
    26761 cttccgacaa gaaggagaac gagaaaattt ccattgaggt aaaggagggg cagagctatg
    26821 aaaaggagga aggcacattg tctgcaaaaa tccgaaggcc tgtgttagtg gatcagaatg
    26881 gaacagaact ttccataaac aaagaaatct cagagtatgt ggacagcctg attgcagaat
    26941 atgaggaaaa taaggctgcc tctgaaaaag aggagggaga cgtacattac gcagtttcca
    27001 atacttatga agtcactcac gacggagagc agtatttttc tatgtatatg gcagcagcgc
    27061 gtattatggg aagcggttca gaaacctatc aaacgtacac cattgataaa aaaactggag
    27121 aagcagtttc tctcggggag ctgctgggaa atgaggaaac gctcaggctt gtcagtgaaa
    27181 atatctctgc ccagatggaa gaacagatga aggaggacgc atctgtcgtc tactttcagg
    27241 catcggaagg cggcttttcc ggtctgaaag gcgatgagag cttttacctg aatcaggacg
    27301 gctctctggt tgttgtgttt gatgaatata ctgttgcgcc aggctccatg ggaatggtgg
    27361 aattcacgat tcccacagag acagcaggcg ctttccgata atgatttcga tcagttaaac
    27421 agccaccagg tcggctgttc tgatatctcc atgcccagct ttttctgaag gctcatggat
    27481 tctgtatttc cttctatgac ctggcagaac ggaatctttc cgtgttccag aaaatggcgg
    27541 ataagaaagg cctccaaacg gaagccatat cttttccgcc tgtattctgg aagaatttct
    27601 aaaagcccca tgcttccttc cagatgctcg cctgcaaagc cagccatccg atccccctca
    27661 aaaatccccc acagctgtcc gcgcgaaatc aattccctca cataatcgcc aggatcctcc
    27721 atcgtgccgt aaaagctgca cacttccttg gcatgctcat ttttcaaagc aatgattcct
    27781 gaatcatcga attcaggagc gtttttctgc atccaggccg cctgattcgt cagtacactg
    27841 gtagcaaaat gatactgcgc ctgtatttcc tccgccagct ctttctgatg aacggcaaac
    27901 tggtggtatg tattctggga caaaatctga cggcatggtt caaaattctc tgccgcaatc
    27961 atgcaggtct ggctgtctgt ttcataaatc atgactccgt cctgttcggc atataaaatt
    28021 tcagcctgct ttatccgaat ggcttctatc atatcaatgt ggtttacaat tcctcgatct
    28081 gccagccatt taaccgcttt ttcgctggtg cttcttttcg tctgatccat ccttttgtac
    28141 ctccttctat aacagcttag cgcccagaaa caaccgtttt gtacgctgcg ccaagccgcc
    28201 cgaaaaatca gaaagcaaaa actttctctg acgaaatcat atcctttaaa acactcattg
    28261 tcaagccagc tcccacacac cagggaaaat aaaaatgtct gtttaagcct ggaaagcagg
    28321 aagagacctg gaaggcggag aaggtaaagc ggctgaaagc cctggaaaga tacaagcagg
    28381 agaacaagaa gcggtatact gggaagctcc agtctctgaa cagagagatt gaggatctga
    28441 ttcgaaaggc cagggaaaca gggggtatgg agcagggaag agcaatcgaa tgctatgcag
    28501 atatggccat tcggactgcc agcaaacggg cctatcttca gggtagatat ccaacgcatg
    28561 gcagtaaggg aagaccttat ggatgtgctc acacatgagt atggctactt catacacagg
    28621 catgcagaag cggactatgt tcagaaatca aaagttttcc gggcgaaaga gctgggcgga
    28681 gagcttatga acggagattg gaagtataat atcaatacaa gatactccgc taaagccaaa
    28741 atagatgcag ctaagattag taaatatgcc acggcaaaat ccttatgagg catttgcgga
    28801 agggttcctg gctatggata aaggcgagaa aataccagac aacatagaga aagtcattaa
    28861 tgcagccaag acaaaagcag gggcgaaaaa tgttgcaaag gaaactggct ctggtataat
    28921 gaaaaatatc aggatacctt ccgccgctct ttcagcaaag aatattacag cggatatagt
    28981 tgatgaaatc cagtccggta tcgatggaat tctgcttgag tacgatgcaa aaatagcttt
    29041 tatatcggta cgagatatga gcattcaatt tccagatacc ccatatatga ttcagtctgg
    29101 tgatatttct caaatgcttt ttcgcacttt tgtaatttat ccataaaacc tctctgtcca
    29161 taaagaaagc cgccctgcaa tgcaaggcgg ctttgaacat tttctttcgg ctttgcagcc
    29221 tactccggtt tgaggttact gcacaacccc tactgaaagc tctgcataac aaggcatccc
    29281 ggtacgctgt tatgcttcaa cgctttggca gacacacgcc gttgcccacc ttatactatt
    29341 attatatgca acttcagaaa atatgtcaat ccccatgaaa aatcaaaaaa tatcttaaaa
    29401 ctttcaaaag taaattccac cgaataaacg gacggtggaa tttacttttg aaagttttag
    29461 aggagagaaa ctgttt
//
LOCUS       DBMDUW010000028        28898 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1178_length_28898_cov_3.602875, whole genome shotgun sequence.
ACCESSION   DBMDUW010000028 DBMDUW010000000
VERSION     DBMDUW010000028.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 28898)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 28898)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28898
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1178_length_28898_cov_3.602875"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            201..1208
                     /locus_tag="ACZPCR_06955"
     CDS             201..1208
                     /locus_tag="ACZPCR_06955"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: protein motif:HMM:TIGR00254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HIR1230652.1"
                     /translation="MRKKTTAGKERTRRQLEQTIAAYQKLAEEDWLTGLYNGRAMEEK
                     AGEYLKRNRAGSMILMDIDQFKKINDTYGHIIGDQLLQDIASVLKKMFPSGCLIGRCG
                     GDEFAIFMPQTLEEEDIQRRCRQIRERFVRVEVNGTVILRLSMTICGGSYHPGFEYKD
                     LFDLADQKIVKEKRSRNGETLERVAVADVNGDEIRIDMKILAKEMREEDPLPGAYCQD
                     YETFKSIYRFVERKMIRKDMGAFLILFTLTDMANEFPTLEQRDYQLELLGQAIQNNLR
                     MGDLYAQYSSCQFLVMLSDTTEENVEMIAGRICQAFYKENKMEDELILHHTYPLKPAG
                     K"
     gene            complement(1231..1788)
                     /locus_tag="ACZPCR_06960"
     CDS             complement(1231..1788)
                     /locus_tag="ACZPCR_06960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005384 - manganese ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0071421 - manganese ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese efflux pump MntP"
                     /protein_id="HIR1230653.1"
                     /translation="MSLTELFILAVGVSMDAFAVAVCKGLSIRRLSWRHAVLVGLYFG
                     GFQAAMPLIGYLLGSHFKDAIASFDHWIAFLLLAAIGFSMIREACSKEEDELDSSLGF
                     KTMSILALATSIDALAVGVTLSFLSVEIVPAVSFIGIITFLFSAAGVKAGHVFGTRYK
                     SKAEFCGGVILILIGLKILIEHLFL"
     gene            2005..3291
                     /locus_tag="ACZPCR_06965"
     CDS             2005..3291
                     /locus_tag="ACZPCR_06965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HIR1230654.1"
                     /translation="MKPYSELTKEELVALSHELNAQYRAFQAKDLKLDMSRGKPSAEQ
                     LDLSMGMMDVLNSSTDLTCEDGTDCRNYGVLDGISEAKELVGDMIEVPAANLIIYGNS
                     SLNVMYDTISRAMTHGIMGSTPWCKLDKVKFLCPVPGYDRHFAITEYFNIEMINVPMN
                     EEGPDMELVEKLVAEDEAIKGIWCVPKYSNPSGISYSDQTVRRLARLRPAAKDFRIFW
                     DNAYGIHHLYEDKQDQVTEILAECKRAGNPDLVYKFASTSKICFPGSGIAALATSHNN
                     LEDIKKQLKIQTIGHDKVNQLRHVRFFKDIHGMVEHMKKHADILRPKFEAVEEILDRE
                     LSGLGIGTWTKPRGGYFICFDSMEGCAKAIVAKCKKAGVVMTNAGATYPYGKDPYDSN
                     IRIAPSYPPLQDLITATELFALCVKLVSVKKLLEDK"
     gene            3454..3903
                     /locus_tag="ACZPCR_06970"
     CDS             3454..3903
                     /locus_tag="ACZPCR_06970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002568471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HIR1230655.1"
                     /translation="MIRKIWNQLAAKCVNRETVSYFIFGVLTTAVDWVGYFALYNMGY
                     SVVFSQTMSWAAAVLFAFITNKLFVFQSTSLKLSRLFSELVSFVACRLFTGILTIAGM
                     ELMVNGLGWSNLFGKIAVSVLSLVLNYILSKLFIFRGREAVSEKRGK"
     gene            3934..6804
                     /locus_tag="ACZPCR_06975"
     CDS             3934..6804
                     /locus_tag="ACZPCR_06975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002588308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HIR1230656.1"
                     /translation="MREDDITGISQEFDLALSRIMPPRGKGAQERDMEMANHHRMRPE
                     AEKEERLEEKDVQAEEKRPHREKTSRPEGGLLKPRDGYIAAFFVPVVIMIIIFAQRGI
                     FPFGEESFLRTDMYHQYAPFFSEFRHKLAEGGSLLYSWDIGLGVNFAALYAYYLASPL
                     NWLLILCPGKYVIEFMTAAIVLKIGLAGLSFTCYLRKRSGVTDFGACFFGIFYALSGY
                     MAAYSWNIMWLDCIVLFPLILLGLEQLVREKKGLLYCISLALSILSNYYISIMICMFM
                     VIYFAVLMVLDWENFKDGWGKCIGLFAGCSLLAGGLAAVVLLPEIFALQSTASGEMSF
                     PQTVESYFSIVDMLARHIGNVQVEIGLEHWPNIYCGTAVLMLFLLYLVCRNISLREKA
                     VYCSLLLFFLASFSVNVLNFIWHGFHYPNSLPARQSFIYIALMLTVCFQAYRNLDRFS
                     DRSILAAFLGAVSFVLLSQKFREGDEAYHFAVFYGAVFFLAVYAGLMVLYRRRGQGER
                     GRKRAALAALLTLFTVCVEAAVNTTCTSVTTTSRTAYTADNEAVETLAASLKESADFY
                     RIEKTDQRTKNDGAWMHFPSVSLFSSMAHADVTEFIKSLGCEGSTNAYSITGSTPFVD
                     CLLSVKYAFYPREQSMDRLEYVQDYQGTYLYANRYALPLGFMIPDIMKNEWHLNMANP
                     ADVQNSLCSLFDAPDVLQEETGLGNGPSLIYTPEEAGEYYAFVSNKQVKSVSLKKGEE
                     KDTFDNINRGYLIEVGMVEAGETLAFQNEEGNEDLGIRLYRYNEAGLEHVYRKLAESP
                     LTLSVWEDDRLKGTVDAGMGGTLFTSIPYDKGWTVTVDGQERQPQELFGAFLGIELEP
                     GSHVIECSYMPEGLKEGMMISLLCAAVLAAAVFISRRRRQKERKAMRRRLSERRTRRE
                     EHLTRKAFERHLEAADAEPVETAEAAGITESEETEKDINQET"
     gene            6818..8191
                     /gene="argH"
                     /locus_tag="ACZPCR_06980"
     CDS             6818..8191
                     /gene="argH"
                     /locus_tag="ACZPCR_06980"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004056 - argininosuccinate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0042450 - L-arginine biosynthetic process
                     via ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HIR1230657.1"
                     /translation="MKLWGGRFTKEENQLVHNFNASISFDQKMYRQDIRGSIAHVTML
                     AKQGILSEEDKCAIIEGLKGILKDVEDGTLLMTPEYEDIHSFVESNLIDRIGEAGKRL
                     HTGRSRNDQVALDMKLYTRDEIDELDGLVKKLLETLLALMEEHLDTYMPGFTHLQKAQ
                     PITLAHHLGAYFEMFFRDLSRLHDIRKRMNYCPLGSGALAGTTYPLDREYTAELLDFY
                     GATLNSMDSVADRDYLIELLSALSTISMHLSRFCEEIIIWNTNEYQFVEIDDSYSTGS
                     SIMPQKKNPDIAELIRGKTGRVYGALVSLLTTMKGIPLAYNKDMQEDKELAFDAMDTV
                     KGCLALFTGMISSMTFKKDVMEKSAKNGFTNATDAADYLVNHGVPFRDAHGIIGRLVL
                     ACIERGCSLDDLPLEAYKEICPVFEEDVYEAISMETCVKKRTTIGAPGQEAMKKVIAE
                     CRKRLEE"
     gene            8221..8745
                     /locus_tag="ACZPCR_06985"
     CDS             8221..8745
                     /locus_tag="ACZPCR_06985"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008723691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HIR1230658.1"
                     /translation="MKKLEEYVRSIPDFPEPGIIFRDITTILQDPDGLKLAVDGLLKT
                     LEGVEYDVVVGPESRGFIFGVPVAYAAHKGFVPVRKKGKLPCKTVSMKYDLEYGSAEV
                     EMHEDSIKPGQKVVIIDDLIATGGTMEAICKLIESLGGEVVRICFVMELAGLEGRKKL
                     KDYPVESLIVYEGK"
     gene            8870..9859
                     /locus_tag="ACZPCR_06990"
     CDS             8870..9859
                     /locus_tag="ACZPCR_06990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HIR1230659.1"
                     /translation="MVGYGKGKRILITLPVTEQHRKLLEQAAGEAELICTQDRTEIEE
                     QLKQADGVIGNVPPVLLKQNKNLGWVQLNSAGTDEYTDEGVLSASAALTNATGAYGIA
                     ISEHMTGMLLNLLKKFPKYMENQKNRQWKDEGEVRPIWGCRILIIGMGDIGTEFARRM
                     KAFGASIAGIRRTVHKKPDWVDELYTMDVLKEELKRADIVAVCLPGTESTRGLFGREL
                     FQCMKQGAVFLNVGRGNIVDTDALADALEEGKLSGAGIDVADPEPLPSSSRLWNCPNV
                     IITPHVSGGFHLSVTLDRIVEISAKNMRAFLGDGEYVSLVDRKTGYKKTETGE"
     gene            10021..12309
                     /locus_tag="ACZPCR_06995"
     CDS             10021..12309
                     /locus_tag="ACZPCR_06995"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006860927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008728 - GTP diphosphokinase activity
                     [Evidence IEA];
                     GO_function: GO:0008893 - guanosine-3',5'-bis(diphosphate)
                     3'-diphosphatase activity [Evidence IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RelA/SpoT family protein"
                     /protein_id="HIR1230660.1"
                     /translation="MEKMDQIKQLDRELEQPADFTSPEVLYQDLIDSIHRYHPSDDIS
                     MVEKAYRLAYDAHKEQKRKSGEPYIIHPLCVAIILADLELDKETIVAGILHDVVEDTV
                     MTTAGVAEQFGNEVALLVDGVTKLTNINWDKDKVEMQAENLRKMFLAMAKDIRVILVK
                     LADRLHNMRTLQYMKPEKQKEKAKETMEIYAPIADRLGISRIKTELDDLALKYLEPDV
                     YYDLAEKISLRKDSREAFVKSIVDEVKSHMDDAGIECKVDGRVKHFFSIYKKMVKQNK
                     TLDQIYDLFAVRIIVDTVKDCYGALGVIHEMYKPIPGRFKDYIAMPKINNYQSLHTTL
                     IGSSGRPFEIQIRTYEMHRVAEYGIAAHWKYKQSGSTKAAMDSAEEKLSWLRQILEWQ
                     KDMSDNKEFLDSLKSDLDLFSDSVFCFTPSGDVKNLPSGSTPIDFAYSIHSAVGNKMV
                     GAKANGVLVNIDYVIKNGDRIEILTSQNSKGPSRDWLKIVKSTQAKNKINQWFKAELK
                     EDNIIRGRDMIDKYCRNKGINYAELNKPEFMEKVMKRYSYKDWDSVLASIGHGGLKEG
                     QVINKMMEAHMKKMEKEKTDATILDSIGDGNKVPVAVSHGKPKSGIVVKGIDDLAVRF
                     SKCCSPVPGDEIVGFVTRGRGISIHRTDCINVINLPEDEKARLIEAEWQQPVGDEAGK
                     ERYTTEIKIFANNRIGMFVDLSKVFTERQIDIKSMNVRTTKQGKATILMTFDIRGIEE
                     LNKLADKLRQIEGVIDIERTAG"
     gene            12369..13016
                     /locus_tag="ACZPCR_07000"
     CDS             12369..13016
                     /locus_tag="ACZPCR_07000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003502041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HIR1230661.1"
                     /translation="MQIKKLTVGYVQTNCYIVSNEETKEAVIVDPGDRGDLIIECCKR
                     EGLDVKAILLTHGHSDHIGALDQVKKAFGAKVYALEDEKELMADENLNLSKSLLGTVI
                     RTEADVWLRDNETVNLIGLPFQVIATPGHTEGSCCYYIESEKALFAGDTLFEGSYGRV
                     DLPGGSSVKLLHSVLDRLFELPEDVTVYPGHLGYTTIGDEKKYNPLAPYKGKLLE"
     gene            13036..14556
                     /gene="hemZ"
                     /locus_tag="ACZPCR_07005"
     CDS             13036..14556
                     /gene="hemZ"
                     /locus_tag="ACZPCR_07005"
                     /EC_number="1.3.98.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen dehydrogenase HemZ"
                     /protein_id="HIR1230662.1"
                     /translation="MIGILLSDQSFEQDIRELLMAFCPGQKFTHDEGEALREAGLIVR
                     GGRTGSGFWLSAERSVSEAENQDGAGTETGPRRFETVSEGRITVDEDSRFETKNRLKR
                     ELYQMMSRLTGKELPWGTLTGIRPTKIALTRLYEGASEQEIHDHMKETYLTSEEKIAL
                     SLDVARREKELLSVVDYENGYSLYIGIPFCPTTCLYCSFTSFPIGKWQGRTELYLNAL
                     FWEMEYVAEKMRGRVLDTIYFGGGTPTSLSPEDLDAILNKVESTFPMDQVKEFTVEAG
                     RPDSITREKLEVLRKHGITRISINPQTMKQETLDLIGRRHTVEQVKETFRLARELGFD
                     NINMDLIVGLPEEDEEDVRATMEEIKKLGPDSLTVHSLAIKRAARLNMFREKYGNLKI
                     TGTQEMIDMTARYAKEMGMEPYYLYRQKNMAGNFENVGYSTPGKACIYNILIMEEKQT
                     IMACGAGTTTKVVFPAENRLERAENVKEVEQYIDRVEEMLLRKEKLICQMEQSSGK"
     gene            14583..15845
                     /gene="hisS"
                     /locus_tag="ACZPCR_07010"
     CDS             14583..15845
                     /gene="hisS"
                     /locus_tag="ACZPCR_07010"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006782803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HIR1230663.1"
                     /translation="MALKKKPVTGMKDILPAEMEIRDYVLGKIKETYRGFGFSAIETP
                     CVEHIENLTSKQGGDNEKLIFKILKRGEKLNLETAKEEADLVDGGLRYDLTLPLSRYY
                     SNNSANLPSPFKALQVGSVWRADRPQKGRFRQFVQCDIDILGDATSLAEIELITATTT
                     ALSRICPDNSFTVRINDRELLKAMASYCGFPEDDCDKVFITLDKMDKIGLDGVAAELL
                     ELGYAAESVEKYKALLDSVKTDADGVRALGETLKGVLKEGTAEGLAEIMETVSSIAEV
                     KFGIEFDPTLVRGMGYYTGTIFEVSMEGFGGSVAGGGRYDKMIGKFTGMDTPACGFSI
                     GFERIVTILLDNGFKVPAAAGKKAYLFEKNIGAEKLAQVLKEASEERKAGVQVLVAQM
                     NKNKKFQKEQLQKDGYTEFKEYYREGLK"
     gene            15900..17711
                     /gene="aspS"
                     /locus_tag="ACZPCR_07015"
     CDS             15900..17711
                     /gene="aspS"
                     /locus_tag="ACZPCR_07015"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015534324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HIR1230664.1"
                     /translation="MAESMLGLKRSHRCTELSTENIGENVTVMGWVQKSRNKGGIIFV
                     DLRDRSGLLQIIFEEADCGEESFAKAEKLRSEFVVAVTGKVEARSGAVNENLKTGAIE
                     IRANSLRILSESETPPFPIEENSKTKEELRLKYRYLDLRRPDLQRNLMTRSRVTTLTR
                     SFLAEEGFLEIETPTLIKSTPEGARDYLVPSRVHPGSFYALPQSPQLFKQLLMCSGYD
                     RYFQIARCYRDEDLRADRQPEFTQIDMELSFVDVDDVLDVNERLLKKLFKEICDYDLQ
                     LPIQRMTWREAMDRFGSDKPDLRFGMELKNVSETVKDCQFVVFKGALENGGSVRGINA
                     EGQAGMPRKKIDALVEYAKGFGAKGLAYLAVNEDGSYKSSFAKFMTEEELSALVKAMD
                     GKPGDLLLFAADKDKVVFDVLGNLRLELARQLDLLKKDDFKFLWVTEFPLLEYSEEQE
                     RFVAMHHPFTMPMEEDLELIDTNPGAVRAKAYDIVLNGTEMGGGSIRIHQSDIQSKMF
                     EVLGFTEEQAKDQFGFLLDAFKYGVPPHAGLAYGLDRMVMLMVGADSIRDVIAFPKVK
                     DASCLMTEAPSPVDVKQLQELGIEVSEEETQEESSEK"
     gene            18328..20202
                     /locus_tag="ACZPCR_07020"
     CDS             18328..20202
                     /locus_tag="ACZPCR_07020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6273 domain-containing protein"
                     /protein_id="HIR1230665.1"
                     /translation="METALAVCVFCLSGMMGSGEMKSYGGPLSGFEAALSTASDAEEE
                     EETAREEIPRSCQLQAYFQTAREYESRLTGEAEDAVPDSRFMITGQEENDIRVLSAAS
                     QIPDGEERTFYVIGKNFVPNGKALAEWFGAGAVYANYLEAEEKEGKDTWYVARMSVWK
                     NGSFDGLKHWEMVRETRASCLGKGTALYRCRETREEKEIVTAPFGHCDSDQDSLCDRC
                     RRRAFGQEEGSKIHAVLGGRNMTFTCIDADYQSSSLPEGGMLYLADQKVETGFFGGYG
                     SCMYEDSQIRRYFRDGFQNGCSLGEALEGISVPGCSGTDYAMSLSREEYGRYQRLIQG
                     GGFFLRDDTGSQVWAVDEKGELQPANPDDPDYGIRPAIVLKKPWAGEAERIHWELGDL
                     QQAEIDGQNLLFRCIDQNYSDHMENHGQTALFLCETVIPADYGSRYELREQEDGSHEY
                     EFCPGPLVNFGQSSDYKHSNIQTWLEQAGDKIYLAKQVQIGTDMAFTGETPKGEYSSF
                     DAVNLSSHPIGAQSLYGKLFLLSVEEAVKYKEFLWTFEGAQEENPETQLSSFSKGYWL
                     RTPMGTGDGADMGYVYGVDLEQGQIRPERIRPTEGTGDAELDATSPFGVRPAFVMPQD
                     "
     gene            20222..24565
                     /locus_tag="ACZPCR_07025"
     CDS             20222..24565
                     /locus_tag="ACZPCR_07025"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230666.1"
                     /translation="MRKKLLLGRTAAFVMAAAIAAGNTVPVQAKGAGEQRREAENLAD
                     EKKTHEDKESFPKASPSEPEEERPEEEEPEEGRPEEEEPERPDSGQDPDQESEQGEKP
                     GEDAPEEEDAPEEEDEEAEEEPEEIPETLSSATGDLWEEWHGAKTDWEGEGTRKNPYK
                     ITNLSELMGLSESVSQGESFAGVYFELQSDIHLGDLETNHGSWNPIGWFQNKTDLGGE
                     PRTAFEGSFDGAEHRISGLKFTKNDENYSYLGLFGLIKNGTVENLALEAEEIAGDDNV
                     ALLAGCVEGSSVIRNVTVNGSVYAEQDAGGIAGEVTGGTNRAVIENCTADSITVNSEG
                     RTGFTGGIAGNVQKAQLADVTVVTQDGDSSRIQGKGYVGGVAGRQNQADIYNSSVSGT
                     IGGNGSRAAGGVTGLYESGDLIVSRFDGEIGRTGQGTAAHEGTFIGTREPKNGFTYGT
                     GKNDQVSYLFAGTAAQAKKAIGSSIADDNAWTYDAHIGYFTDYQRRYALVRGTGEQDG
                     GERFFYEELEDGIQHIITQKLGEKLDELTKKRLFHLDHYAPGNSGEPVRGYLVSIPRI
                     DTKNANGTFDNDVAVLTAISSTNNSYYRQIDKDHPSAVAPGCTVTAATAPKNQNGNRY
                     QLVYDENEPGQAKPPTFTDEEGERRPMAYVNGGSYSFQMPEANTELNAEYVKVTTELA
                     ITPKETVISVIQTRTGDRKQPQIMTEVKDQEGRLIAKYLNGSENSEVQVLPVRIHAEH
                     NGQGSAADRTVQWSIDNQDLLNFEEGWTEGYTQKDARVLPNINSKFIQEIILRETKNQ
                     ADSGYQEAIKNTVYTDTAVVTASTNPATSADNQAVTGTCRVNVSFQIVDQTTVRVEQM
                     ELNQSNLAFHVTRRLTGDRKNPEETYTADAPYYLDTSLKPSQPFFKNVSWKTREGQKI
                     LSLKPSGQNEQSCQVSVVFDENGVSHPAWIQNIVNQDNSRKEASGGYLRLSGTGGVQE
                     MITATSEDQTHGVVSADCRVNVSFQTEDETVIHPEAVLLDKNELDYDLSFQFAGDTRS
                     EIIKKEGFGIRDTLKASVLPQLEDREEYEPYNRKGLWSSSEPDAVSVKDGVLSVNDKA
                     AWIEEALKSSPYSADKEVVITARTEDGGKETSCRIKLHFQAKAVQADREEEQFDIVLT
                     KSGPRSNPSFTWKGTDGKQMKAELHPERKGEKPIWKSGDSAVLTVTSDGLAAPKTADS
                     AGNAEAEWIKNAMKTYPYSGETRTFLEVSDPEGVSKDRILVRLTFKMFDRTYASGGGS
                     SSGSGGGSSSGSRGGSASGPGASSSLKGVSGPAGESAGLSGQAEGIFGQWTCTPEGFW
                     TFEAGRTYKNEWAYIKNPYAAEGQNQADWFRFDEEGRMVTGWFTDTDGNEYYLWPESD
                     GTKGHITVGWQWIDMDQDGARECYYFNPVSDGTKGKLIKSPEVPEGYQVNAHGAWMIN
                     GTVQTKGQRQE"
     gene            24562..25377
                     /locus_tag="ACZPCR_07030"
     CDS             24562..25377
                     /locus_tag="ACZPCR_07030"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230667.1"
                     /translation="MKKAAGAILAAFLTGAGAVSALAAEGYANGGYWSNQDTMEWTLQ
                     NGTAEVYGRGPVFSELHPEITDPEHYLEEKFCLNRAEDDENREKESLTEEEEKRLKEF
                     LHSFDWIHSDEVSRAQKAYERIANGHSGNQYKMPDPSLRSIRFPVLTGGFGLCENFAG
                     EYAALAELMGLQCEAYDSDLNHRACLLKIDGRWFRVDPTCSSAFFSNASFYPVDYEKE
                     KRRIGEASKEKWDTYFKEHPDRLLEEDFLMMDRLARGEITAEEYNSWAKHYYK"
     gene            25495..>28898
                     /locus_tag="ACZPCR_07035"
     CDS             25495..>28898
                     /locus_tag="ACZPCR_07035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003508337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HIR1230668.1"
                     /translation="MWMVCLPYLPPLQFQAAENRNVVTLTSAHGEFGGEHKLYCIDKG
                     GLAIWGIADDGDQYEMHSPSTMRIPLSQREQEYIFWGILTLQASMGVTEAVSAVKNIK
                     VNAAAQGKTPITSLVTEEDLKALIYRADVRAKYPWMEEAAADTEGYLKMAGLISEGGG
                     VSQSGQKIPDFLSGCTSEEAAYPVSADDRTIHFAEDGSDARFIAEVPLLFSGGSGLSY
                     TETPPDGWICTKTDKEISFYNPSPNPPRLLVKFAVEGTGYASAESAYRSEGELFEDCL
                     QLWECIQCSGRHTGGTPPNSPTEIHQRMVWLDLKMAQSGLFASVGGTAVSEEAEGSVV
                     FHVFRHAEDFTSAYNVQLFKFDHETGQPLENARFVLYERFDDKGEVNTERDGPAHIYK
                     GGSPYASYHKDNPVIWDNFRRVGTVVTDENGYGQKRITHGYHYDKTFCNGHPAPVFLF
                     VPEPEEDEETGEILNSSEIEQAKAVNQLTAKKWMDTAEDCEKQASGAFEGVHFHWYME
                     GVDREAIEEISDSGGEEGTTPSAGNTQEAPPEEAYDKSGCHQDMEETYHRFIALRYSY
                     AFSEFQARDGYIRHDLHPDALPIEIITTDSSENGANAVFSGEYSKKEQLEGEEKAELS
                     ARPRDLVQAPFLKATESGAEEETEEEKDETEEEGESQTEEEEEKPEEEPETEEGRWEA
                     EAETEEIKEEKATSSVPELQWTRTDFSFRMPEMRTGETASDSLFPPAYEEGLLSGSKG
                     EEIKPEPNDRYSHCSGADGEKEAWRVYDHRTEMEFHINKKDLDLSAGESEEYSAYGEA
                     QGDGTLEGAVYGLFAAEDIRHPDGKTGVVYRAGNLAAVAVSDQNGDASFLANTEAPGR
                     TYDYKTGTIVNTPDGWAADAPGNLYTEDISYDDYTPDHQYERTYADNEKNNGNCWIGR
                     PLLEGSYYVKELSRSEGYELSVGNKRHPLTNRGQDLQTQTAGKGDGYAVIASPLYAEE
                     QTAEDGPGAGPNELFFSVRSRDTKDQRYDVLLSQLPEGVRFYRKETGIKKTEVSAGTG
                     IYEKVFLKNPDGSPKYIRAEYEGQYPRYNEDGSLMTKEFPVDCGAERIRQVPVRGLDL
                     DIVQEMMMEPEKGMTEAENQEELLKPASESELLFIKGKTERILRKHG"
BASE COUNT         8065 a         6107 c         8592 g         6134 t
ORIGIN      
        1 aagttgtgcc ttgctgcata aaaagcggcc agcaacattt agctgctggc cgggaaaatt
       61 ttatattttt tctctgtcct cttgacgggg agcagttcaa aacggctttt ctgtcttatt
      121 tttacttatc tgaggattga agttttaagc cctctgtgct actgttaaaa aaagcgctaa
      181 cggaacgaga gggattgaga atgagaaaga agacaacagc aggaaaagag agaacgcgga
      241 ggcagctgga acagacgatt gcagcttatc agaagctggc ggaggaggac tggctgacag
      301 gtctctataa tggcagagct atggaggaga aggcgggcga atacctgaaa cggaacagag
      361 cggggtcaat gattctcatg gatatcgacc agtttaaaaa gatcaacgac acatacggcc
      421 acattatcgg ggatcagcta ctccaggata ttgcgtcggt gctgaagaaa atgtttccct
      481 ccggctgcct gatcggaagg tgcggaggcg acgaatttgc aatttttatg cctcagacac
      541 tggaagagga ggatatccag agacggtgca ggcagattcg agagcggttc gtgagagtgg
      601 aggtgaacgg cacggtgatt ctccggcttt ccatgaccat ctgcggagga agctatcatc
      661 cgggctttga gtacaaggat ctgtttgatc tggcggatca gaaaattgtg aaggaaaaga
      721 ggagcagaaa cggagagacg ctggagaggg tggctgtggc cgacgtaaac ggcgacgaga
      781 tacgcattga catgaagatt ctggccaagg agatgcggga ggaggatcct cttccaggcg
      841 cctactgcca ggactatgag acgtttaaga gtatttaccg gtttgtagag agaaaaatga
      901 tacgaaagga catgggagcc ttcctgatcc tgttcacgct cacagacatg gccaatgaat
      961 ttcccaccct ggaacagcgc gattaccagc tggagctgtt aggccaggcg attcagaata
     1021 accttcgtat gggggatctt tacgctcagt acagcagctg ccagttttta gtcatgctgt
     1081 ccgacacgac ggaggagaat gtggagatga tcgccgggcg tatctgccag gcgttttaca
     1141 aggagaataa gatggaggat gaattgattc tccaccacac ctatccgtta aagccggcag
     1201 gaaaataagc tcctgccggg cggaagaaga ttacaaaaac aggtgctcga tcagaatttt
     1261 aagcccaatg agaatcagga tcactccccc gcagaattct gccttggatt tgtaccgggt
     1321 tccaaataca tggccggcct tgactccggc tgccgagaaa agaaaagtaa taattccgat
     1381 aaacgagaca gcaggcacaa tttcaacgct taaaaaggac agggtgacgc ctacggcaag
     1441 agcgtcgatg ctggtggcca gggccagaat gctcatggtt ttaaagccca gagagctgtc
     1501 cagctcatcc tcttccttgg aacaggcctc ccggatcata ctgaagccga tggctgccag
     1561 aagaaggaag gcaatccagt gatcgaaaga agcgatggcg tccttgaagt gggaacctaa
     1621 caggtatccg atcagcggca tggccgcctg aaagcctccg aaatagagtc ctactaaaac
     1681 ggcgtggcgc cagcttaaac gcctgataga cagccctttg cagacggcga cggcgaacgc
     1741 gtccatagac actcccacgg cgagaataaa aagctctgtc agtgacatgg tgaatttcct
     1801 cctgagattt gagataaatt aaaacacgga gccttattat accattgtcc ctttaaggag
     1861 gcaatctttt gtcgggaatt gcaggaagag cgcaaaaaat gtcttgtcaa tgaaatcatg
     1921 ttttgatatg ataaattcgg tgaaataatc agttataaga ataaatggct gggaaagcct
     1981 gataacaagg aggattttga gggaatgaag ccttacagcg aacttacaaa agaagaatta
     2041 gttgcgctca gccacgagct gaatgcacag taccgtgcgt ttcaggccaa ggatttaaag
     2101 cttgacatgt ccagaggaaa gccgtctgca gagcagttag acctttccat gggtatgatg
     2161 gacgtgctta acagctctac ggatctgacc tgcgaggacg gtacggactg ccgcaattat
     2221 ggcgtgctgg acggaatcag cgaggcgaag gaactggttg gagatatgat cgaggttccg
     2281 gcggccaatc tgattatcta tggaaactcc agcttaaatg taatgtatga taccatttcc
     2341 cgcgccatga cacacggtat tatgggaagc actccctggt gcaagcttga caaggtgaag
     2401 ttcctctgtc ctgttccggg atatgacaga cattttgcaa ttacagaata ctttaacatt
     2461 gagatgatca atgttcctat gaacgaggaa ggcccggata tggagctggt ggagaagctg
     2521 gttgcagagg acgaggccat caagggaatc tggtgtgttc ccaagtactc caacccaagc
     2581 ggaatttcct actccgatca gacggtgcgc cgtctggcca gactgagacc ggctgccaag
     2641 gatttcagaa ttttctggga taatgcctat ggcatccacc atttgtacga ggacaagcag
     2701 gatcaggtga cggagattct ggcagagtgc aagagagcgg gaaatccgga tcttgtttac
     2761 aaatttgcct ccacttccaa aatctgcttc ccgggatccg gcatcgcagc gttagctacc
     2821 tcccacaaca atctggagga catcaagaag cagttaaaga ttcagaccat cggacacgac
     2881 aaggtaaacc agctgcgcca cgtgagattc tttaaggata tccacggaat ggtggagcac
     2941 atgaagaagc atgccgatat tctccgtccg aagttcgagg cagttgagga gattcttgac
     3001 agagagttaa gcggactggg aatcggaacc tggacaaagc cgagaggcgg ctactttatc
     3061 tgttttgact ctatggaggg atgcgcgaag gctatcgtag ccaagtgcaa gaaggccggc
     3121 gttgtgatga caaacgcagg agcgacatat ccttacggaa aggatccgta cgacagcaat
     3181 atccgtattg ctccttccta tccgccgctt caggacctga ttacagccac agagctgttt
     3241 gctctctgcg taaagttagt cagtgtaaag aagctgttag aggataagta gcctgagcgc
     3301 ataccggcgc tgaaattttc aaatataaaa gggcggggac atgtgatttg caggctcccg
     3361 cccttgcttt ttgcagaaaa acacattaca atagcaaaag aaaagcaaaa gaacgatcaa
     3421 tagctaaaaa agaagttgag gaagtaagtg catatgatta gaaagatatg gaatcagctg
     3481 gcggcaaaat gcgtcaaccg cgagacagta tcttatttta ttttcggcgt cctgacgacg
     3541 gctgtggact gggtgggata tttcgccctc tacaacatgg gatattccgt agtgttttcc
     3601 cagaccatgt cctgggcggc ggcggttttg tttgcgttta tcaccaacaa gctgtttgta
     3661 tttcagagca cttccctgaa gctgtcaagg ctctttagcg agctggtttc ctttgtggcc
     3721 tgcaggctgt ttacagggat tttgacgatt gcgggaatgg agcttatggt aaacggcctg
     3781 ggatggtcca atctgtttgg aaagattgcg gtttctgtcc tgtctctggt attgaactat
     3841 atactcagca agctgtttat tttccgcggc agagaggctg tctctgaaaa acggggaaaa
     3901 taaagagggc ggcgaaagct ttgcggaggt tgtatgagag aagacgatat aacagggatt
     3961 tcacaggaat ttgatctggc gttaagccgg atcatgccgc ccagagggaa gggagcgcag
     4021 gagagagaca tggagatggc gaatcatcat agaatgcggc cggaggcgga gaaggaagaa
     4081 cggctggagg aaaaagacgt tcaggcagaa gaaaagcggc cccacagaga aaaaacgtct
     4141 aggccggagg gcggcctttt aaagcccaga gacggctata tcgcggcttt ttttgtgccg
     4201 gttgttatta tgattattat ttttgcccag agaggaattt tcccttttgg ggaggagagc
     4261 tttctgagaa cggacatgta tcaccagtac gcgccgtttt tctcagagtt ccgccacaag
     4321 ctggcggagg gaggaagcct tctgtacagc tgggacatcg gcctgggcgt caactttgcg
     4381 gctctttacg cctattacct ggccagccct ttaaactggc ttcttatttt atgtccgggc
     4441 aaatatgtca ttgagtttat gactgccgcc attgtgctca aaatcggact ggcaggtctt
     4501 tcttttacct gttatctgag aaagagaagc ggcgtcacgg atttcggcgc ctgctttttc
     4561 gggatttttt acgccctgtc aggttatatg gcggcctaca gctggaatat tatgtggctg
     4621 gactgcattg tcctgtttcc gctgatcctt ttgggtctgg aacagctggt gagagagaaa
     4681 aagggacttc tctactgtat ttctctggcg ctctccatcc tgtccaacta ctatatctcc
     4741 attatgatct gtatgttcat ggtgatctat tttgccgtgc ttatggtgct ggactgggag
     4801 aattttaagg acggatgggg gaaatgcatc ggcctgtttg ccggatgttc gcttctggca
     4861 gggggattgg cggctgtggt gctgctgccg gaaattttcg cccttcagag cactgcttcc
     4921 ggggagatga gctttcccca gacagttgag agctattttt ccattgtcga catgctggcc
     4981 cgccacattg gaaacgtaca ggtggagatt ggtctggagc actggcccaa tatttactgc
     5041 ggaacggcgg tgctgatgct gtttctgctc tatctggtct gcagaaatat ttcccttcgg
     5101 gaaaaggcag tgtactgctc cctgcttctg ttttttctgg ccagcttttc agtcaatgtg
     5161 ctgaacttta tatggcacgg cttccactat ccaaacagtc tgccggccag acagtccttt
     5221 atctacatcg ctttgatgct gacggtctgc tttcaggcct acaggaacct ggatcggttt
     5281 tccgacagaa gcattctggc agcctttctg ggggccgtct cttttgtgct cctgtcccag
     5341 aaattcaggg agggagacga ggcctaccat ttcgccgtat tttacggcgc ggttttcttc
     5401 cttgccgtgt atgcagggct gatggttctg tacaggagga gagggcaggg agaaaggggc
     5461 agaaaacggg cggctctggc agctcttctg actctgttta cggtctgtgt ggaggcggcg
     5521 gtgaacacca cctgcaccag cgtgaccacc accagccgga cggcttatac ggccgacaac
     5581 gaggcggtgg agacgctggc ggccagcctg aaggaaagcg ctgattttta ccggatagaa
     5641 aaaacggatc agagaacaaa gaacgacggc gcctggatgc attttccgtc tgtttccctg
     5701 ttttcctcta tggcccacgc cgatgtgacg gaatttataa aaagcctggg ctgcgaagga
     5761 tctactaatg cgtacagcat tacggggagc acgccgtttg tggactgcct tctgtctgtc
     5821 aaatacgcct tttaccccag ggaacagagc atggatcggc tggagtacgt ccaggattac
     5881 cagggcacct atctctatgc caaccggtac gcccttccgc tgggctttat gattcccgat
     5941 atcatgaaaa acgagtggca tttgaatatg gcgaacccgg ctgacgttca gaattccctc
     6001 tgcagcctgt ttgacgcgcc ggatgtgctt caggaggaga ctggccttgg aaacggcccc
     6061 agcctgatct acacgccgga ggaggctggg gagtattacg cctttgtctc caacaaacag
     6121 gtgaaatcgg tttccctgaa aaagggcgag gaaaaggaca cctttgacaa tatcaaccgc
     6181 ggctatctga tagaagtggg aatggtggag gctggggaga cgctggcctt ccagaacgaa
     6241 gagggaaatg aggatctggg aatccgcctt taccggtaca atgaagcggg gctggagcat
     6301 gtatacagaa agctggcaga gagccctctg actctgtctg tctgggagga tgacaggctg
     6361 aagggaacgg tggacgcagg catgggggga accctgttta catccattcc ctatgataaa
     6421 ggatggaccg tgacggtgga cggacaggaa agacagcctc aggaactgtt cggcgctttt
     6481 ctgggcattg agctggaacc gggaagccat gtgatagaat gttcctacat gccggaagga
     6541 ctgaaagagg gaatgatgat ctcgctgctt tgcgcggctg ttttggccgc cgcagttttt
     6601 atatcccgaa gaagacgtca gaaggagcgc aaggctatgc ggcgtcgtct ttcggagcgg
     6661 agaacccgcc gggaggagca tctgacgaga aaggcttttg aaaggcatct ggaagcggca
     6721 gatgcagaac cagtggaaac agcagaagca gcagggatca cagagtcgga agagacagaa
     6781 aaagacataa atcaggagac ataaggagga aacagccatg aaattatggg gaggacgatt
     6841 caccaaggag gagaaccagc tggtacacaa ctttaacgct tcgatttcat ttgatcagaa
     6901 gatgtaccgc caggatatca gggggagcat cgctcatgtg acgatgcttg caaagcaggg
     6961 aattctctct gaggaagaca aatgcgcgat tatcgagggg ttaaaaggaa ttttaaagga
     7021 tgtggaggac ggaacgcttc tgatgacgcc agagtacgag gatatccact cctttgtgga
     7081 gagcaatctc attgaccgca tcggggaggc aggaaagcgc ctccacacag gccgcagccg
     7141 gaatgatcag gtggccctcg acatgaagct ttataccagg gacgagatcg acgagctgga
     7201 cggcctggta aagaagcttc tggagactct tctcgctctg atggaggagc atctggacac
     7261 ctatatgccg ggctttaccc atcttcagaa ggcccagccg attacattgg cccaccatct
     7321 gggagcttac tttgagatgt ttttcaggga tctttccagg cttcacgata tcagaaagag
     7381 gatgaattac tgtccgcttg gctcaggagc cctggcaggc acgacttacc ctctggaccg
     7441 ggaatacacg gcagaacttc tggactttta cggagcgacc ctgaacagca tggattctgt
     7501 ggctgacaga gactatctga ttgagctgtt aagcgcactg tccaccattt ccatgcatct
     7561 gagccgcttc tgcgaggaga ttattatctg gaatacaaac gaataccagt ttgtggagat
     7621 tgacgattcc tatagtacgg gaagcagcat tatgccccag aagaagaacc ctgacatcgc
     7681 ggagctgatc cggggaaaga cgggacgcgt gtacggggct ttagtcagcc tgttaaccac
     7741 catgaagggc attccactgg catataataa ggatatgcag gaggataagg agctggcctt
     7801 tgacgctatg gatacggtga agggatgtct ggctctgttt acaggcatga tctccagcat
     7861 gacctttaaa aaggacgtga tggagaagag cgcgaaaaac ggctttacca acgcgacaga
     7921 cgcggcggat tacctggtaa accacggtgt tcccttccgt gacgcccacg gaattatcgg
     7981 ccgcctggtg ctggcctgca ttgagagagg ctgctcctta gacgaccttc cgctggaggc
     8041 ctacaaggag atttgtcctg tgtttgagga ggacgtttac gaggccatca gcatggaaac
     8101 ctgcgtgaag aagagaacta ccatcggcgc tcccggacag gaggcgatga agaaggtgat
     8161 tgccgaatgc cgaaagaggc tggaagaata ggagaacaga aagagagagg aaacagcgtt
     8221 atgaagaaat tagaggaata tgtgagaagc attccggatt ttccggagcc aggcattatt
     8281 ttcagggata tcaccacgat tcttcaggat ccggacggcc tgaagctggc ggtagacggc
     8341 ctgttaaaga ccttagaggg cgtggagtac gacgtggtag tgggaccgga gtccagaggc
     8401 tttatctttg gagtgccggt ggcctacgcc gcccacaagg gctttgtgcc ggtccgcaag
     8461 aagggaaagc tgccctgtaa gaccgtttcc atgaagtacg atctggaata cggaagcgcg
     8521 gaggtggaaa tgcacgagga ttccattaag ccgggccaga aggttgtcat tatcgacgat
     8581 ctgattgcta caggaggaac catggaggcc atctgcaagc tgatcgagag cctgggcgga
     8641 gaggttgtgc gcatctgctt cgtcatggag ttagccggcc ttgagggaag aaagaagctg
     8701 aaggactatc cggtagagtc cctgattgtt tacgagggaa aataaaggac agacggcagg
     8761 cgccggaatg ctgcaggaag cggcgttccg gcgctttggc gcatacatat gtgagcgtgc
     8821 ggaataaaga ggccattagt aaaaatgaga atgaaaggaa ggtttctata tggtgggata
     8881 cggaaaagga aagaggattc tgataacact gccagtgaca gaacagcaca ggaaattgct
     8941 ggagcaggca gcaggagagg cagaattgat ctgcacacag gacagaacag aaatagagga
     9001 acagctgaaa caggcagatg gagtaattgg caatgtgccg ccagttctgt taaaacagaa
     9061 taaaaatctg ggctgggtac agttaaacag cgcggggaca gatgaatata cagatgaagg
     9121 agtgctgtcg gcctctgcag cgctgactaa cgctacggga gcttacggga tcgccatttc
     9181 agagcatatg acagggatgc ttttaaatct tctgaaaaaa tttcccaagt acatggaaaa
     9241 ccagaaaaac cgccagtgga aggatgaggg ggaggtgagg ccgatctggg gctgcagaat
     9301 tctgatcata ggcatgggag acattgggac agagtttgcc agaagaatga aagcatttgg
     9361 agccagcata gcaggaatca ggagaacagt gcataaaaaa ccagactggg tagacgagct
     9421 ttataccatg gatgtgctga aggaagaact gaagagggca gacattgtgg cagtctgcct
     9481 gccaggaact gagtccacca gagggctgtt tggaagagag ctttttcaat gtatgaaaca
     9541 gggagcagtc tttttaaacg taggaagggg aaatatcgta gatacggacg ctttggcgga
     9601 tgctctggag gaggggaagt tgtccggcgc tggaatcgat gtggccgatc cggagccgct
     9661 gccatcatcc agccgcctgt ggaattgtcc taatgtgatc attaccccac atgtatcagg
     9721 aggatttcac ctgagcgtta ccctggatcg gattgtggaa atcagcgcaa agaatatgag
     9781 agctttcctg ggagacgggg agtatgtcag tcttgtggat aggaagacag ggtataaaaa
     9841 gaccgaaaca ggggaataat cctagaaatt ttacagggaa acacccaaaa acgcctgcac
     9901 gtccaggagg aagcagaaaa gaattgcatt ttctgacaaa aaaaattata atagtgataa
     9961 ttctctataa aacgacaaag gcatgatggg agcagatgcc tgaagctggg aggcgtatgt
    10021 atggaaaaga tggatcagat aaaacaactg gatagagagc tggagcagcc ggctgatttt
    10081 acaagcccgg aggtattgta tcaggatttg attgacagta tccacagata ccacccgtcc
    10141 gatgatattt cgatggtgga gaaggcctac aggcttgctt atgatgccca taaggagcag
    10201 aagcgcaaat ctggggagcc gtatattatc catcctctgt gcgtagcgat tatcctggct
    10261 gatttagagc tggacaagga gacgattgta gcgggtattc ttcatgatgt agtggaggat
    10321 accgtgatga ctactgcagg cgtggcggaa cagtttggaa acgaggtagc gctgttagta
    10381 gacggcgtta cgaagctgac caatattaac tgggacaagg acaaggtgga gatgcaggcg
    10441 gagaacctgc ggaagatgtt tttagctatg gccaaagaca tccgggttat tctggtaaag
    10501 ctggcggatc gtcttcacaa tatgcggact cttcagtata tgaagccgga gaagcagaag
    10561 gaaaaggcca aagagaccat ggagatttac gcgccgatcg cagaccgcct gggaatttcc
    10621 agaatcaaga cggagcttga tgatctggct ctcaagtatc tggagccgga cgtatactac
    10681 gatctggcgg agaagatttc cctcagaaag gattccaggg aagcctttgt aaagagcatt
    10741 gtggacgagg ttaagagcca catggacgat gcgggaatcg agtgcaaggt ggacggccgg
    10801 gtgaagcatt tcttcagcat ttataagaag atggtgaagc agaacaagac tctggatcag
    10861 atttacgatc tgtttgcagt caggattatc gtggatacgg tgaaggactg ctacggagcc
    10921 ctgggcgtaa ttcacgagat gtacaagccg attccaggcc gctttaagga ttacatcgcc
    10981 atgccgaaga tcaataatta ccagtctctt cacacgactc tgatcggaag cagcggacgt
    11041 ccctttgaga tccagatccg cacctacgag atgcacaggg tggctgagta cggaattgcc
    11101 gcccactgga aatataagca gagcggaagc acgaaggccg ccatggacag tgcggaggag
    11161 aagctctcct ggctgcgcca gattctggag tggcagaagg atatgtccga caataaggag
    11221 ttcctggatt ccttaaagag cgatctggat ctgttctcag acagcgtgtt ctgctttacc
    11281 ccctcgggag atgtgaagaa cctgccaagc ggttctactc ccattgattt tgcctactcg
    11341 atccacagcg cggtgggcaa taagatggtg ggcgccaagg ccaatggagt gctggtaaat
    11401 attgactatg taattaaaaa cggcgaccgg attgagattc tgacttccca gaacagcaag
    11461 ggccccagcc gggactggct taaaattgtc aagagcaccc aggcgaagaa caagatcaat
    11521 cagtggttta aggcggagtt aaaggaagac aatattatcc gcggccgcga tatgattgac
    11581 aaatactgcc gcaataaggg cattaactac gcggagctta acaagccgga gttcatggaa
    11641 aaggtgatga agcgctattc ctacaaggac tgggattctg tccttgcctc catcggccac
    11701 ggcggcctga aggagggcca ggtcatcaac aagatgatgg aggcccatat gaaaaagatg
    11761 gagaaggaga agacagacgc tacgatcctg gattctatcg gagacggaaa taaggttcct
    11821 gtggcggtgt cccacggcaa gcccaagagc ggcattgtgg tgaagggaat cgacgatttg
    11881 gcggtgcgtt tctccaagtg ctgcagccct gttccgggag acgagattgt gggctttgtg
    11941 acgagaggcc gaggtatttc catccacaga acagactgca tcaacgtgat aaacctgccg
    12001 gaggacgaga aggcaaggct catcgaggcg gagtggcagc aacctgtggg agacgaggca
    12061 ggcaaggagc gctacaccac ggagattaag atttttgcca ataaccggat cggcatgttc
    12121 gtggatctgt ccaaggtgtt cacagagcgg cagattgaca ttaaatccat gaacgtgcgg
    12181 acgaccaagc agggaaaggc cacgatttta atgaccttcg acatccgggg aattgaagaa
    12241 ctgaataaac tggccgacaa gctgagacag attgaaggcg taatagatat agagagaact
    12301 gccggataag cagttttctc tatgtttccg tattttgcta aacttatgct gaaggagagg
    12361 acaggcgaat gcagattaag aagctgacgg taggctatgt gcagaccaac tgctatattg
    12421 tatcaaacga ggagacgaag gaagcggtga ttgtagatcc cggcgacaga ggggatttga
    12481 ttatagagtg ctgtaagcgc gaagggctgg atgtgaaggc cattttgctg actcacggcc
    12541 attccgacca tattggagcc ctggatcagg tgaagaaggc ctttggagcg aaggtctacg
    12601 cgcttgagga cgagaaggag ctgatggcgg acgagaatct gaacctttcc aagagtcttt
    12661 tgggaactgt gatccggacg gaggcagatg tgtggctgag agataacgag acggtaaatc
    12721 tgattggcct gcccttccag gtcatcgcca cgccgggcca tacggaggga tcctgctgct
    12781 actacataga gagcgagaag gcgctgtttg caggagacac gctcttcgag ggttcctacg
    12841 gacgggtgga tctgcctggc ggaagctctg tcaagctgct tcactcagtc cttgaccgtc
    12901 tgtttgagct tccggaggat gtgacggtgt atccgggaca tctgggatat acgaccattg
    12961 gagacgagaa aaagtataat ccgctggctc cctacaaggg aaagctgtta gaataaggga
    13021 aagacaggaa acaagatgat aggaatactg cttagcgatc aatcatttga acaggatatc
    13081 agggaacttc tcatggcctt ctgtccgggg cagaaattta cccacgacga gggggaggcc
    13141 ctgcgggagg cagggcttat tgtgcggggc ggacggacag gcagcgggtt ctggctttct
    13201 gcggagcgct ctgtgtcaga ggctgagaat caggacggcg cgggaactga gactgggccc
    13261 cgcaggtttg agacggtttc tgagggcagg attacagtgg acgaggacag ccgttttgag
    13321 acgaagaaca ggcttaagag ggagctgtac cagatgatga gccgtcttac cggaaaagag
    13381 cttccctggg ggactctcac cggcatccgt cccacgaaaa ttgccctgac gaggctttat
    13441 gagggggctt ccgagcagga aatccacgat cacatgaagg aaacctacct gaccagtgag
    13501 gagaaaattg ccctgagcct tgatgtggcc agacgggaga aggagcttct gtcggtggta
    13561 gattatgaga acggctacag tctctacatt gggattccgt tctgccccac tacctgcctc
    13621 tactgctcct ttacttcctt ccccatcgga aaatggcagg gaaggacaga gctttattta
    13681 aacgctctgt tctgggagat ggagtatgtg gcggagaaga tgaggggccg cgttctggat
    13741 accatttatt ttggaggcgg aactcccacc tccctgagcc cggaggatct ggacgccatc
    13801 ctgaataagg tggaaagcac cttccccatg gatcaggtga aggaatttac tgtggaggcg
    13861 ggacggccgg acagcattac cagggagaag ctggaggttt taagaaagca cggcattacc
    13921 cgtatttcca ttaatcccca gaccatgaag caggagacgt tagacttaat cggccgccgc
    13981 catacggtgg aacaggtgaa ggagaccttc cgtctggcca gggagctggg ctttgacaat
    14041 atcaatatgg atctgattgt gggacttccg gaggaggacg aggaggacgt cagggccact
    14101 atggaggaga ttaaaaagct ggggcccgac agcctgaccg ttcattctct ggccatcaag
    14161 agagccgcaa ggcttaacat gttccgggaa aaatatggaa atctgaagat caccggaacc
    14221 caggaaatga tcgacatgac ggcccgttat gcaaaagaga tgggcatgga gccctactat
    14281 ctctacaggc agaagaacat ggcgggcaac tttgagaacg taggctacag cacgcccggc
    14341 aaggcctgca tttacaacat tctcattatg gaggagaagc agaccattat ggcctgcgga
    14401 gccggaacca ctaccaaggt ggtgttcccg gcagagaacc gtctggagag ggcggaaaac
    14461 gtaaaagaag tcgagcagta catcgaccgg gtggaggaga tgcttcttag gaaggaaaag
    14521 ctcatctgcc agatggaaca gagctcagga aaataaacag ttagaaaaca ggagagatta
    14581 ccatggcttt gaagaaaaaa ccagtaaccg gaatgaagga tattctgccg gcagagatgg
    14641 aaatccgcga ctatgtgctt ggaaagatca aggaaactta ccgcggattc ggcttttctg
    14701 ccattgagac gccgtgtgtg gagcacatcg agaacctgac cagcaagcag ggcggcgaca
    14761 atgagaagct gattttcaag attttaaaga gaggcgagaa attaaacctg gagacggcga
    14821 aggaggaggc cgatctggtg gacggcggtc tgcgctatga cctgacgctc cccttatccc
    14881 gttactattc caacaattcc gctaatctgc caagcccgtt caaggcgctg caggtgggaa
    14941 gcgtgtggag ggctgaccgt ccgcagaagg gacgtttcag acagtttgtg cagtgcgata
    15001 tcgacatttt aggggacgcc acctctctgg ctgagatcga gctgattaca gccaccacca
    15061 cagccctgtc ccgtatctgc ccggataact cctttaccgt ccgcatcaac gacagagagc
    15121 tgttaaaggc catggcatcc tactgcggtt tcccggagga cgactgcgac aaggtgttca
    15181 tcactctgga caagatggac aagatcggtc tggacggcgt ggcggcagag cttctggagc
    15241 tgggctatgc ggctgagagc gtggagaagt acaaggcgct gctggactcc gtaaagacag
    15301 acgcagacgg cgtgagagcc ctgggagaga cattaaaggg cgttttaaag gaaggcacag
    15361 ccgaggggct ggctgagatt atggagaccg tatcttccat cgcagaggtg aaattcggca
    15421 ttgaatttga cccgactctc gtaagaggaa tgggatacta tacaggaacg attttcgagg
    15481 tgtccatgga gggcttcggc ggatctgtgg caggcggagg ccgctacgac aagatgatcg
    15541 gcaagtttac aggcatggat acgccggcct gcggcttttc catcggtttt gagagaattg
    15601 taaccattct tctggacaac ggcttcaagg tgcctgcggc ggcaggaaag aaggcgtatc
    15661 tcttcgagaa gaacatcgga gcagaaaagt tagcccaggt tttaaaggaa gcttccgagg
    15721 agagaaaagc tggcgtacag gttctggtag cccagatgaa caagaataag aaattccaga
    15781 aggagcagct ccagaaggat ggctacacag agtttaagga gtactaccgg gaaggattaa
    15841 agtaggcttt agcccctacc ggatctacat ttttacaaaa ttcaggagga aaataaatca
    15901 tggcagaatc aatgctggga ctgaagcgtt cccacagatg tacagagctg tccacagaaa
    15961 atatcggtga aaacgtcacc gtcatgggat gggttcagaa gagcagaaat aaaggcggaa
    16021 tcattttcgt ggacttaagg gatcgctccg gcctgcttca gattatcttc gaggaggcag
    16081 actgcgggga ggaaagcttt gcaaaggctg agaagctgag aagcgagttc gtagtcgcag
    16141 tgacaggaaa ggtggaggcg cgttccggcg ctgtcaatga gaacttaaag acaggagcca
    16201 tcgagatccg cgccaattcc ctgcggattc tttccgagtc cgagactccg ccattcccca
    16261 tcgaggagaa ctccaagaca aaggaggagc tgagattaaa ataccgttac ctggatctga
    16321 gaagaccaga tctgcagaga aacctgatga ccagaagccg cgtgactacg ctcaccagaa
    16381 gctttctggc agaggaggga ttcttggaga tcgagactcc gactctcatc aagagcacgc
    16441 cggagggagc cagggactac cttgtgccca gccgtgtgca tccaggcagc ttctatgccc
    16501 ttccccagtc tccacagctc tttaagcagc tgttaatgtg ctctggctat gaccgttact
    16561 tccagattgc cagatgctac agagacgagg atctgagagc agacagacag ccggagttca
    16621 cacagatcga tatggagctt tcctttgtgg atgtggatga tgtgctggat gtcaacgaga
    16681 gactgttaaa gaagcttttc aaggagatct gcgattatga tttacagctt ccgatccaga
    16741 gaatgacatg gagagaggcc atggaccggt tcggttccga caagccggat ctccgctttg
    16801 gaatggagct taagaacgtg tccgagacag tgaaggactg ccagttcgtc gtatttaagg
    16861 gcgctctgga aaatggcggc tctgtcagag gaatcaatgc agagggacag gctggaatgc
    16921 cgagaaagaa aatcgacgct ctggtagagt atgccaaggg cttcggcgct aagggactgg
    16981 cttatctggc tgtcaacgag gacggatcct acaagtcctc tttcgctaaa tttatgacag
    17041 aggaagagtt aagcgccctt gtaaaggcca tggatggaaa gccaggcgac ctgttattat
    17101 ttgccgcaga caaggacaag gttgtatttg acgtgctggg caacctccgt ctggagctgg
    17161 caagacagct tgacctgtta aagaaggatg actttaagtt cctctgggtg acagagttcc
    17221 cgttattaga gtactcagaa gagcaggagc gctttgtggc tatgcaccac ccatttacca
    17281 tgccgatgga ggaggatctg gagcttattg atactaatcc aggcgcagtc cgcgcaaagg
    17341 catatgatat cgtattaaac ggaactgaga tgggaggagg ttccatccgt atccaccaga
    17401 gcgatatcca gtctaagatg tttgaggtgc tgggcttcac agaggagcag gcaaaggatc
    17461 agttcggctt cctgttagac gccttcaagt acggagttcc gccgcacgca ggccttgcat
    17521 acggtctgga ccgcatggtc atgctgatgg tgggagcaga cagcatccgc gacgttatcg
    17581 ccttcccgaa ggtgaaggac gcttcctgtc tcatgacaga ggccccgtct ccggtagatg
    17641 taaagcagct gcaggagctg ggaatcgagg tttctgagga agagacacag gaagaaagtt
    17701 ctgagaaata aaagcagaaa aaaacagaaa aaaaagcaga agggaacagc tggcaggagc
    17761 aggaaaaagc gctcctgcca gccggtttca tactgcgaaa gcagtccgtt gcaggcaaag
    17821 aaggcttttt cataaaaagc tataaaaatt ttaacagaca gttgaaatat cacccggatt
    17881 gtgatatgat gagtacagtt tcaggaaaca ttctggtttc ctattctttc cggtctgctc
    17941 agaccgacgt tccagacagt aatgagaaga taaaggatat acaggacagc agagaactgc
    18001 agtaccctga tttgacggct ttttccgttt attgggagaa aagagcccgt tttgcgcttc
    18061 ttgaatttct attgccgaag gcattctaag acaaatctgt tatcacagcg caatttatca
    18121 aaataattca aataattgaa aataacaaaa tattagtaaa aacagcaatc gttcagccgg
    18181 gagaaacagg aggtttaaag gaaggcttaa ataaatggtt tggaaccgga ataacagcgg
    18241 gacaggaaac aataggaaac cagcctgaga aaggaggggg aaaagacgag acgggtcaat
    18301 aggaaggcac cgctcaggac aagccagatg gagacagctc tggctgtatg tgtgttctgc
    18361 ctgtcaggaa tgatgggaag cggggaaatg aaaagctatg gaggaccgct ttccggtttc
    18421 gaagcggcgt tatctactgc ctctgacgca gaggaagagg aggagaccgc acgagaggag
    18481 attccaagga gctgccagct tcaggcatat tttcagactg ccagagaata tgagagcaga
    18541 ctgacagggg aggcagaaga cgcagttcca gacagccggt ttatgattac agggcaggag
    18601 gaaaatgata tcagagtact gagcgcggcg tcgcagattc cagacggaga ggagaggact
    18661 ttctatgtaa tcggaaagaa ttttgtgcca aacgggaagg ccctggcaga gtggtttggt
    18721 gccggagctg tgtacgcgaa ctatttggaa gctgaggaga aagaaggaaa ggatacctgg
    18781 tacgttgcca ggatgagcgt atggaaaaat ggaagctttg atgggctgaa gcactgggaa
    18841 atggtaaggg agaccagggc ttcctgtctg ggaaagggaa cggcgctgta ccgctgccgt
    18901 gagacgaggg aggagaagga gattgttacc gcgccgtttg gacactgcga ttcggatcag
    18961 gattccctct gcgaccggtg ccggcggagg gcctttggac aggaggaggg atctaagatt
    19021 cacgctgttt taggtggacg gaacatgacg tttacctgca ttgacgctga ttatcagagc
    19081 agcagcctgc cggagggagg gatgctctat ctggccgatc agaaggtgga gacaggattt
    19141 tttggaggat atggctcctg catgtatgaa gacagccaga tcaggagata tttccgcgat
    19201 ggctttcaga atggatgttc cctgggagaa gccctggaag gaatttcggt tcctggatgc
    19261 agcgggaccg attacgccat gagcctgtca agggaggagt atgggagata ccagagactg
    19321 attcagggag gaggcttttt cctaagggat gatacaggca gccaggtgtg ggcggtcgat
    19381 gaaaaaggag aacttcagcc agcaaatccc gatgatccag attatggcat acgcccggct
    19441 attgtgctga aaaagccatg ggcaggcgag gcggaacgga tccactggga gttaggagat
    19501 ctgcagcagg cggagataga cggacaaaac ctgctgtttc gctgtattga ccagaattat
    19561 tcggaccaca tggaaaacca tggacagacg gccctgtttc tctgcgagac ggtgatcccg
    19621 gctgattatg gatccagata cgagctgaga gagcaggagg atggaagcca cgaatacgaa
    19681 ttttgtccag gccctctggt aaatttcgga caaagcagcg attataagca ttcaaatatt
    19741 caaacatggc tggaacaggc gggagataaa atttatctgg caaagcaggt gcagattgga
    19801 actgatatgg cgtttacagg ggaaacgccg aaaggagagt attcctcctt tgacgcggta
    19861 aatttaagca gccatccgat aggggctcag tcgctctatg gaaagctgtt tctgctgtct
    19921 gtggaggaag cggtgaaata taaagagttt ctctggacct ttgagggagc acaggaagaa
    19981 aatccggaga cgcagctgtc ttccttttca aaaggatact ggctgagaac tccaatggga
    20041 acaggggacg gagcagacat gggatatgtg tacggggtgg atttagagca gggacagatt
    20101 cggccggaac ggatccggcc gacggaagga acaggagatg cggagctgga tgcgacgtcg
    20161 ccttttggcg tcaggccagc ctttgtgatg ccgcaggatt agagaaagag gaggagacag
    20221 attgagaaaa aaattattat tgggacggac agcagccttt gtaatggctg ccgccatagc
    20281 agcgggaaat acagttcccg tacaggcgaa gggggccggg gaacagcgaa gagaagcaga
    20341 gaatctggca gacgagaaga agacgcatga ggataaagaa tcttttccta aggcgtcgcc
    20401 gtcagaaccg gaggaagaaa gaccagagga ggaagaaccg gaggaaggaa gaccggaaga
    20461 ggaagagccg gagagaccgg attcaggaca ggatccggat caggaatcag agcagggcga
    20521 aaaaccagga gaagatgctc cggaagaaga ggatgctccg gaagaggagg atgaggaggc
    20581 agaagaagag ccggaggaaa ttccagagac gctcagctcg gctacaggcg atctgtggga
    20641 ggaatggcat ggagcgaaga cggactggga gggagaggga accagaaaaa atccatataa
    20701 aattacaaat ctttcagagt tgatggggct ttcagagtca gtttcacagg gagaatcctt
    20761 tgcaggcgtt tattttgagc tgcaaagcga cattcatctg ggagatttgg agacaaacca
    20821 tggttcctgg aatccgattg gatggttcca gaacaaaaca gatctggggg gagaaccgcg
    20881 cactgccttt gagggcagct ttgacggagc ggaacatagg atttcagggc tgaaatttac
    20941 gaaaaatgat gaaaattatt cgtatttggg actgtttggg ctgataaaaa atggaacggt
    21001 cgaaaacctg gcgctggaag cagaagagat tgcaggggac gataatgtag ctcttctggc
    21061 aggctgcgtg gagggctcgt ccgtgatccg aaatgtgacg gtaaacggat ccgtctatgc
    21121 ggagcaggac gccggaggaa tcgcaggaga ggtgacggga ggaaccaatc gcgctgtgat
    21181 tgaaaactgc acggctgaca gcattacggt taactcagag gggcgaaccg gctttacggg
    21241 aggaattgcg ggaaatgtgc agaaggcgca gctggccgac gtgacggtcg tcacccagga
    21301 cggggacagc agccgcattc agggaaaggg atatgtagga ggcgtggcag gccgccagaa
    21361 tcaggcggat atttacaaca gctctgtctc cggaacgata ggaggaaacg gaagcagggc
    21421 ggcaggagga gtgacgggcc tttatgaatc aggcgatttg attgtatccc ggtttgacgg
    21481 agaaatcgga agaaccggac agggaacggc tgcccacgag ggaactttta ttgggacgag
    21541 ggagccgaag aacggtttta cctatggaac gggaaagaac gatcaggtat cctacctgtt
    21601 tgcaggaacg gccgcccagg caaaaaaggc gataggttcc tccattgcag atgacaatgc
    21661 ctggacttat gacgctcaca tcggatactt tacggattac cagagacggt atgccctggt
    21721 gagaggaacg ggggagcagg acggaggaga gagatttttc tatgaggaac tggaggacgg
    21781 gattcagcat attattacgc agaagctggg agaaaagctg gacgagctga caaagaagcg
    21841 cctgttccat ctggatcact atgcgcctgg aaacagcgga gagcctgtca ggggatatct
    21901 tgtctccatt cccagaattg atacgaagaa tgcaaacgga acttttgaca acgacgtggc
    21961 ggttctgacg gcgatctctt ctacaaacaa cagctattac aggcagattg acaaggatca
    22021 tccttcagcc gtcgctccag gatgtacggt tactgcggcg actgcaccga aaaatcagaa
    22081 tggaaacagg taccagctgg tttacgatga aaatgagccg ggccaggcga agcctccgac
    22141 cttcacagac gaggaaggag aacgccgccc catggcatat gtaaatggag gctcctactc
    22201 gtttcagatg cccgaggcaa acacagagct gaatgccgag tatgtgaagg tgacaacaga
    22261 gcttgccata acgccaaaag aaaccgttat ttctgtgatt cagacgagaa cgggagacag
    22321 gaagcagccg cagattatga cagaggtaaa ggatcaggaa ggaaggctga ttgcaaaata
    22381 tttgaatgga agtgaaaact cggaggttca ggtgcttccg gtcagaatcc atgcagagca
    22441 caacggccag ggttctgcgg cagatcggac ggtgcagtgg tccattgaca accaggatct
    22501 gctgaacttt gaggaagggt ggacggaagg atatacgcag aaggatgcca gagtgcttcc
    22561 aaacataaac tccaaattta ttcaggaaat tattctcaga gagacaaaaa accaggcaga
    22621 cagcgggtat caggaagcca taaaaaacac ggtatataca gatacagcag tagttacagc
    22681 gtctacgaat cctgccacaa gcgcagataa tcaggctgtc acaggaacct gcagagtcaa
    22741 tgtttctttc cagattgtag atcagaccac agtgcgggta gaacagatgg agctgaatca
    22801 gagtaatctg gcttttcatg tgacaaggag gttaactggg gacagaaaaa atccggagga
    22861 gacatataca gctgacgctc cctattatct ggataccagt ttaaagccgt cgcagccgtt
    22921 ttttaaaaat gtttcctgga agaccaggga gggacagaaa attttgtctc tgaaaccgtc
    22981 gggacagaat gaacagagct gtcaggtgtc tgtcgtattc gatgagaatg gagtcagcca
    23041 tcctgcctgg attcagaata ttgtgaatca ggataacagc aggaaggaag catcaggcgg
    23101 atatctcagg ctgtcgggaa ccggcggggt ccaggagatg attacggcta cctctgagga
    23161 tcagactcac ggagtagtga gcgctgactg ccgcgtcaat gtttcgtttc agacagagga
    23221 cgagacggtg attcatccgg aagccgttct ccttgataaa aatgagctgg attatgattt
    23281 gtcgtttcag tttgcagggg atacccgctc ggaaattata aaaaaagaag gatttggaat
    23341 cagggacacg ctgaaagcct ctgttctacc ccagttagag gacagggaag agtatgagcc
    23401 ttataacagg aagggtttat ggagctccag cgagccggac gccgtgtcgg tgaaggacgg
    23461 cgttttatcc gtaaacgaca aggccgcatg gattgaggag gctctgaagt cttctccata
    23521 cagcgctgac aaagaggtcg tcataactgc caggacagag gatgggggaa aggagacatc
    23581 ctgccgcata aagcttcatt ttcaggcgaa agcggtgcag gcggaccggg aagaggaaca
    23641 gtttgacatc gttcttacaa aaagcggccc cagatcaaac ccctccttta cctggaaggg
    23701 aacggacggg aagcagatga aggcagaact gcatccagag agaaaaggcg aaaaaccgat
    23761 ctggaagagc ggagattctg ctgtacttac agtgacttca gacggtctgg cagcgccgaa
    23821 aacggcagac agcgcgggga acgcggaggc ggaatggatt aagaatgcga tgaaaaccta
    23881 tccttattca ggagaaacca ggacattttt ggaagtatca gatccggaag gagtgtcaaa
    23941 agacaggatt ttggtcagac tgacgtttaa aatgtttgat agaacgtatg cttcaggagg
    24001 aggctcgtcc tccggatcag ggggaggctc ttcttccgga tcgagaggag gatctgcttc
    24061 aggcccagga gcttcctcca gcttaaaagg cgtctctgga ccggcaggag agagcgctgg
    24121 cttatctggc caggcagaag gaattttcgg tcaatggacc tgcacaccgg aaggattctg
    24181 gacatttgag gcaggaagaa cctacaagaa cgagtgggcc tatattaaaa atccttatgc
    24241 ggcagaaggg cagaatcagg cagactggtt ccgttttgac gaggagggcc gtatggtgac
    24301 aggatggttt acagatacag atggaaacga gtattacctc tggccagagt cagatggaac
    24361 gaaaggccat ataacagtcg gatggcagtg gatcgacatg gatcaggacg gagcaaggga
    24421 atgctattat tttaaccctg tatctgatgg gacaaaggga aagctaataa aatcgccaga
    24481 ggttccagaa gggtatcagg taaacgctca cggagcatgg atgataaacg ggacagttca
    24541 gacgaaagga cagagacagg aatgaaaaaa gcggcaggag cgatattggc agcgtttctg
    24601 acaggggctg gggcggtttc cgccctggcc gccgaaggat atgcaaacgg gggatactgg
    24661 tcaaatcagg acacgatgga gtggactctt cagaacggaa cggcagaggt ttacggcaga
    24721 gggcctgtat tcagcgagct gcatccggaa attacagatc cggagcacta tttagaagaa
    24781 aagttctgcc tgaacagggc ggaagacgac gagaaccggg aaaaggaaag tttgacagaa
    24841 gaagaggaaa aacgattaaa agaatttctc cacagctttg actggattca ctcagacgag
    24901 gtcagcaggg ctcagaaggc ctacgagagg attgccaatg ggcattcggg aaatcagtat
    24961 aaaatgccgg atccttccct tcgctccatc cggtttccgg ttttgacggg aggattcggg
    25021 ctgtgtgaaa attttgccgg cgagtatgcc gcgctggcag agttgatggg ccttcagtgc
    25081 gaggcctatg acagcgatct gaaccacaga gcctgccttc tcaaaataga cggcaggtgg
    25141 tttcgagtag atccgacctg ttccagcgca tttttcagca acgcatcctt ttatccagtt
    25201 gactatgaaa aagaaaagag acggataggc gaagcgtcaa aggaaaaatg ggacacgtat
    25261 tttaaggagc atccggaccg cttactggaa gaggattttt taatgatgga tcgccttgcg
    25321 agaggggaaa ttacggcaga ggagtataac agctgggcaa agcattacta taaatagcct
    25381 ggcaggttgt cagcgaaatt tggaaagagg ggatgggcag tggaaaaatt cagcagatat
    25441 tgcttcaggg gaaaaggccg gcgcgcggta tcttttgttt tatcaatcgt tttaatgtgg
    25501 atggtgtgtc ttccgtacct gcctccgctt cagttccagg cagctgaaaa cagaaatgtg
    25561 gtaacgttga cgtctgccca tggagagttt ggcggagaac acaaactgta ctgcattgat
    25621 aaaggcggcc tggcaatctg gggaattgca gacgatggag atcagtatga gatgcacagt
    25681 ccttccacca tgaggattcc cctgtctcag agagagcagg aatatatttt ctggggaatt
    25741 ttgacgctgc aggcatcgat gggggtgaca gaggctgtca gcgcagtaaa aaatataaaa
    25801 gtaaatgccg ctgcgcaggg gaaaactccg attaccagtc tggtgacgga ggaggattta
    25861 aaagccctta tttacagagc cgacgtgagg gcaaaatatc cctggatgga ggaagcagcg
    25921 gctgatacag agggctacct caaaatggca gggctgattt cagaaggagg gggcgtctct
    25981 cagagcgggc agaaaatccc ggatttcctg tctggctgca cctctgagga ggcggcctat
    26041 ccggtaagtg ctgacgaccg tacaatacat tttgctgaag atggttcaga cgccaggttt
    26101 atcgctgaag tcccgctcct tttttcaggc ggctctggtc tgtcttatac agagacgccg
    26161 cctgacggat ggatctgcac aaagacggat aaggaaataa gcttttacaa tccgtctcct
    26221 aatcctccga gacttctggt gaaatttgca gtggagggaa ccggctacgc ttctgcagaa
    26281 agcgcctacc gttcagaagg ggagctgttt gaggactgtc tccagctgtg ggagtgcatt
    26341 cagtgctctg gcaggcatac aggaggaacg cctccaaaca gccccacaga aattcatcag
    26401 cgtatggttt ggctggatct taagatggcg cagtcaggtc tttttgcctc tgtgggagga
    26461 acggcagttt cagaagaagc agagggaagc gtggtatttc atgtgttccg ccatgcagag
    26521 gatttcacgt ctgcctataa tgtgcagctg tttaagtttg atcatgagac tggacagccg
    26581 ctggaaaacg ccagatttgt tttatacgag cgttttgacg ataaaggaga agtgaataca
    26641 gagagggatg gaccggccca tatttacaaa gggggaagtc cgtatgccag ctatcacaag
    26701 gacaatccag tcatctggga taattttcgg agagtcggaa cggtcgtaac tgacgagaac
    26761 ggctatggac agaagaggat tacccatgga taccactatg ataaaacctt ctgcaacggc
    26821 catccagcgc ctgtatttct tttcgttcca gaaccggagg aggatgagga gacgggagaa
    26881 atcctcaatt cttcagaaat tgaacaggca aaagccgtca accagcttac ggcaaaaaaa
    26941 tggatggata cagctgaaga ctgtgaaaaa caggcgtcag gggcatttga aggggtacac
    27001 tttcactggt atatggaagg ggtagaccga gaagcaatag aagagatatc tgattcagga
    27061 ggggaggaag gaaccacgcc ttctgctgga aatacgcagg aagcgccgcc agaggaggca
    27121 tatgacaagt caggctgcca tcaggatatg gaggaaactt accacaggtt tattgctctg
    27181 aggtacagct atgcattttc agagtttcag gccagagacg ggtatatccg ccatgacctg
    27241 catccagacg ctcttcccat cgagattatt acaacagatt cttctgaaaa tggtgccaac
    27301 gctgtgtttt ctggtgaata cagcaaaaaa gagcagctgg agggggagga aaaggcagag
    27361 ctttctgcac gcccgagaga tttagtacag gcgcctttct taaaagccac tgaatcaggc
    27421 gcagaagagg agacggaaga agaaaaagac gagacagagg aagaggggga atcccaaaca
    27481 gaggaggaag aagagaagcc agaagaagag ccggaaacag aagaaggcag atgggaagca
    27541 gaggcggaaa cagaagagat aaaggaggag aaggcgacgt cgtccgtccc tgagcttcag
    27601 tggactagga cagatttttc attccgtatg cctgagatgc gaacaggcga aactgcttcg
    27661 gacagcctgt ttccgcctgc ctatgaggag gggcttttgt ccggaagcaa aggggaggag
    27721 ataaaaccag agccaaacga caggtacagc cactgcagcg gagctgacgg ggagaaggaa
    27781 gcctggaggg tttacgatca cagaacagag atggaatttc acatcaataa aaaagatttg
    27841 gatctttccg caggagaatc ggaagaatac agcgcttacg gggaagcgca gggagatgga
    27901 accttagagg gagcggtata cggcctgttt gcagcggagg atatccgcca tccggacgga
    27961 aaaacgggag tggtttaccg cgcgggaaat ctggctgctg tggcggtttc ggatcagaac
    28021 ggggacgctt cttttctggc caatacggaa gcccctgggc gtacttacga ctacaagaca
    28081 ggaacaattg tgaacacacc ggatggctgg gcggctgatg cgcctggaaa tttatacaca
    28141 gaagatattt cctatgacga ctacacgccg gatcatcaat atgagagaac ctatgcagat
    28201 aatgaaaaaa ataatggaaa ctgctggatt gggcgtcctc ttctggaagg aagctattat
    28261 gtcaaagagc tgtcccgttc ggaagggtat gaactttctg tgggaaacaa aaggcatcct
    28321 ttgaccaaca gagggcagga tcttcagaca cagacagccg ggaaggggga cggatatgct
    28381 gtgattgctt ctcctctcta tgcagaagag cagaccgcag aagacggccc cggagcaggt
    28441 ccaaacgaac tgtttttttc agtccgatcc agagatacaa aggatcagcg ctatgatgta
    28501 cttttatcac agcttccaga gggcgtcaga ttttaccgga aagaaacagg aataaaaaaa
    28561 acagaggttt ctgcaggtac gggaatttat gagaaggtgt ttctgaagaa tccggacgga
    28621 tctcccaagt atatcagagc agagtacgaa ggacagtatc ccaggtataa tgaggatgga
    28681 agcctgatga ccaaagaatt tccggttgac tgtggggcag aacggatcag gcaggttccg
    28741 gtgagaggac ttgacctgga tatagtccag gagatgatga tggagcctga aaaaggcatg
    28801 acagaggcgg aaaatcagga agagctttta aagcctgcgt cagaatcaga acttttattc
    28861 ataaaaggga agacggaaag gattctcagg aagcatgg
//
LOCUS       DBMDUW010000029        27932 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1219_length_27932_cov_3.128885, whole genome shotgun sequence.
ACCESSION   DBMDUW010000029 DBMDUW010000000
VERSION     DBMDUW010000029.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 27932)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 27932)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27932
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1219_length_27932_cov_3.128885"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(211..1146)
                     /locus_tag="ACZPCR_07040"
     CDS             complement(211..1146)
                     /locus_tag="ACZPCR_07040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007861192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230669.1"
                     /translation="MAVNVLEYAKLFETNLDLLAVQTLKTGFMDANSGQVRYSGGDEV
                     KVPKLSVQGLGNYSREEGYVRGAVNLSYQTLKMTQDRGRKFMIDAMDVDESNFLATAG
                     NVMGEFQRTMLVPEIDAYRISKLAATAMGVDGDVQAEYGYTVDGSSIIKKIKTAVKRI
                     RENGYDGEIDILATYDVVGAVEEAALGKLTAMTFSQAGINTQVPQIDGCPLIAVPSNR
                     MYTAITVYDGKTGGQEAGGYKKGEKGLDVNFIAIARNVPIAVTKQDKMRIFTPDTYQA
                     ANAWSIDYRRYHDLWVLDNKKGSLFVNVKDAKPSD"
     gene            complement(1161..1706)
                     /locus_tag="ACZPCR_07045"
     CDS             complement(1161..1706)
                     /locus_tag="ACZPCR_07045"
                     /inference="COORDINATES: protein motif:HMM:NF018515.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019069 - viral capsid assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HIR1230670.1"
                     /translation="MEFLKKLFDGKALTYEELETAVNGAGIKLADVSSGYARQGDLEA
                     KERELKAANESIRELTGKLKGFDGVDVEGLKADVKSWETKYNNDMRALKKAAAVDMAV
                     MKAGARNAKAVKALIDMDKVTVKDDGTIEGLDIEKIKETDGYLFNVETVTTEGNGVAA
                     GRAADGAENLNDVIAKAMGII"
     gene            complement(1660..2016)
                     /locus_tag="ACZPCR_07050"
     CDS             complement(1660..2016)
                     /locus_tag="ACZPCR_07050"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230671.1"
                     /translation="MDDREDMMNLRELWKKYDSYNQFNVSVLSEEIKTQGVQLVYPAG
                     SVIISLGDFPDYVYFIQSGSAIGTRDYHSRERKPISNNILKRLSSDKRFFNANKKRGK
                     RNGIFKKAVRRQGPHI"
     gene            complement(2029..2865)
                     /locus_tag="ACZPCR_07055"
     CDS             complement(2029..2865)
                     /locus_tag="ACZPCR_07055"
                     /inference="COORDINATES: protein motif:HMM:TIGR04041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjW family glycine radical enzyme activase"
                     /protein_id="HIR1230672.1"
                     /translation="MDLKAPVNKIIPFSSVDGFGNRTAVFLQGCNQNCLYCHNPETIH
                     MCRNCGACVNTCPAGALMMENGRVSYDYSKCCNCDTCLKTCQFDASPKIRNMTAGQLY
                     EEIRGFFPFVNGITTSGGECSLYLDFLKEFYTLVQAAGKTTFMDTNGQIPLWEREDVL
                     EVTDKTMIDLKAGSEEDHLHLTGRGLSVVAENIRRMAAMDKLYEIRTVVVPDAVDNLK
                     TVELGSNLIANYPNVRYKLIKFRHYGVRENFSSTREPDDAYMKLLRDTALKAGVKDVL
                     IV"
     gene            complement(2865..4361)
                     /locus_tag="ACZPCR_07060"
     CDS             complement(2865..4361)
                     /locus_tag="ACZPCR_07060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007861342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjI family glycine radical enzyme"
                     /protein_id="HIR1230673.1"
                     /translation="MASFDMTNDILYTIKNPKVTFNQRLKDMAKIAENSIELVEYTEK
                     SKEYFANGAMMDMFEGKTPYRTRYCVPDYEKFLKQGSEFLMLEPPKDIWDAVGNLLCL
                     YHNIPADGGLPVYIGNLGTLLDPFVTDEAEAEKAIRFLLVHVDRTISNAFCHANLGPE
                     DTKAGRIVLKLTKEMQRPCPNMTLLYRDDTPDSFMLAALDTAMAAAKPSFANDKMYRK
                     EMGDYAVVSCYNTLPIGGCGLTLVRLNMNRLPELAKSPEDLLDRVIPDAVTAVCDAID
                     SRCRFIVDECHYYENNFLYREGLIRKEKDYMIGMFGFVGLAECVNKALGLTEPGERYG
                     HNEKADAFGEAIMDRIRAEIDKRPAAYGKYGLHAQVGVMEDTESTPGGRIPIGEEPEL
                     PLQIQHFTRMHKGCDAGCGELFPFDHTVGNNPQYLLDILKGAFSTGARYLSFYSGDSD
                     LVRVTGYLVKRSDIEKFNKEQMTLNEATVNGAVVDKNLHLLDRKVRGN"
     gene            complement(4391..5308)
                     /locus_tag="ACZPCR_07065"
     CDS             complement(4391..5308)
                     /locus_tag="ACZPCR_07065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009537331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1230674.1"
                     /translation="MKALADLIFTSDFFYSIFRVATPLLFASMGAVVSDVAGVPNIAL
                     EGMMLIAAFAGMYFSYLFGSAWAGLAFAILFAVLAAGILAFFTLYYKTNIILGGIAIN
                     SLASGGTIFFLYLVAHDKGTSVALTSKVLPNINIPIIEQIPIIGPAISGHNVLTYLSI
                     LAVVFTYLLLKKTSLGYHIRAVGEKKEAADSVGISVMKTQAAALLISGVMSGLGGAFM
                     SMGYVSWFSRDMVSGRGWIALAAEAMGQRGAVGTAATSLLFGVADALSNAVATLGWPS
                     DLVKTIPYCATLIGLAVFSIRACRKMKRA"
     gene            complement(5305..6348)
                     /locus_tag="ACZPCR_07070"
     CDS             complement(5305..6348)
                     /locus_tag="ACZPCR_07070"
                     /inference="COORDINATES: protein motif:HMM:NF014684.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1230675.1"
                     /translation="MSRERSFNIIRTAVSMLVAILVAFVIILLVSDQPVESIKTFLLA
                     PFSSKRYLGNIVETAVPLIFSGLAMAVMFKANLFNLGGEGVFFISGIAGSFLAIWLKM
                     PPIVFPIACIAAGALAGMIIMLVPGVLKAKYGANEMVTSLMMNNILLGVGLYLLNNVM
                     RDPKVASLVSYKYRSNALLSNIVPGTRIHSGFLIAVLCAVLVYLFMFKSKWGYEIRMT
                     GNNAKFASYSGINVTKVIIIVHLAAGAIAGAGGLIECIGMHKRFEWTALPGYGFDGAM
                     IAMLAGNNPLGVIGAAFFVSYLRIGADLVNRSSDIPTEMIAILQSIIILLISAERFLH
                     KYKQNWIEKEVKG"
     gene            complement(6345..7895)
                     /locus_tag="ACZPCR_07075"
     CDS             complement(6345..7895)
                     /locus_tag="ACZPCR_07075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002601545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1230676.1"
                     /translation="MEQYLLEMNNISKIYSNGIAANKNVNFNLKKGEIHALVGENGAG
                     KSTLMKILFGMEPPSSGEIILRGEPVRFSSSKDAIAHGIGMVHQHFMLVESFTAAQNI
                     ILGMEPKKGLFVSEEEAIRFTKEISKKYNLDVDAEAVTQTLPVGVKQKIEILKALARG
                     AEILILDEPTAVLAPQETDQLFDELINLKKQGHTIVFISHKIPEIKRISDRITVMRAS
                     QFVGCCETKDVTEQEISAMIMGCEMDTSIQKTVPKPGDVKIQVKNLSYTDKNQVKLLN
                     NINFGVRGGMIFGIAGVQGNGQVELVELMTKKRMIKDGDILLNGTSVKNLSIEQIRNM
                     QFGYVPEDRMEQGIAGQESIAENMVSNRYGSKEFCRGGLLNYKKILKFAEERIKSYEI
                     RCSGTGQNVGMLSGGNMQKVVVARECSHNPEVLIAEQPTRGVDIGAAHIIHKKMMELR
                     DQGCAVLLISADLSEALKLSDVIAVMYEGEIVAYFDNTEGLNEEKLGLYMLGLEKHSE
                     EQIRRAEG"
     gene            complement(7913..9058)
                     /locus_tag="ACZPCR_07080"
     CDS             complement(7913..9058)
                     /locus_tag="ACZPCR_07080"
                     /inference="COORDINATES: protein motif:HMM:NF014647.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HIR1230677.1"
                     /translation="MKKLTAAALAVCMTAGMMTGCSAPDPEETTAPSKAAESAAEAQG
                     EGDAEAVNPEDYKVALMIPGNLGDKSFFDASFRAIEPIEEQLGVTVDYVEAGLDTSKY
                     YPVLVDMCEADYDLILTISSNNDDALVQAAEEYPDQLFINLDDELTDPPANVYIMGTK
                     NNEMSFLAGAAAALKAAELGEDKIGFVGGMDIPGINEFLVGYIEGAQAVNPDIKVATS
                     YVGSFTDTAKGKENALLLYNSGLSVIFAAAGQSGLGVIDAAVAQNKFAIGVDSDQAEA
                     LKETKPEMAGVIITSAIKNIPENAVKAVDRAMKGEIPYGTREVFGIAEDAVGIAENEF
                     YEALLSEEDRAKIEELKGQVVAGEIEMTPTTGITTEKVNEIREAVRP"
     gene            complement(9140..10045)
                     /locus_tag="ACZPCR_07085"
     CDS             complement(9140..10045)
                     /locus_tag="ACZPCR_07085"
                     /EC_number="3.2.2.-"
                     /inference="COORDINATES: protein motif:HMM:NF013335.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HIR1230678.1"
                     /translation="MNGTERMKKTTILIDTDFGDDTDDAAAFRLALSCGCLDIAAVTT
                     VFGDTKKRAEMVLEFLSLYGRHDIPAAAGHEKALIERAHSAGPEPIQYPVLKNKTGLL
                     SDRPAEDLIIQCVREHPDLVILAMGSMTNLAMAFLREPELMRHVKILAMGGAFFDAKP
                     EWNIACDPEAARLVMEQSENLIMMGLDVTKYLRISPEMLDGWRKRKDPAMDYFLEGVS
                     LFQKATGFPVTFHDVLLVAYLLDPETVSLQRGDYTVELSGSMTRGTLVSLSNYYEIHS
                     PEEGRLQFAVHVDTNRFFQILEQYF"
     gene            complement(10348..11028)
                     /locus_tag="ACZPCR_07090"
     CDS             complement(10348..11028)
                     /locus_tag="ACZPCR_07090"
                     /inference="COORDINATES: protein motif:HMM:NF015945.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspA/IM30 family protein"
                     /protein_id="HIR1230679.1"
                     /translation="MAGIFDRIGMIVKSNLNELLDKFEDPEKIIDQTIIDAVQEYGNM
                     KKTALDVLANETLTKKQLDELKKEAETWHSIAVKALTAGNEADAKKALEKENDCQTRA
                     ASQEAAYEAARQAADTVRGKLRQMEGEINDMKQKAAQIKAKAVTAKVTKKAAELTSRD
                     TDRGAFDAFARMEEKADRELARAQASEALSAGSEEAEAEDLMKKYGGASPSDADLALE
                     KLKAELGL"
     gene            complement(11051..12187)
                     /locus_tag="ACZPCR_07095"
     CDS             complement(11051..12187)
                     /locus_tag="ACZPCR_07095"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230680.1"
                     /translation="MGRGGGRSGGGRSGGRSGGFSRGGSRGFSSRRSAGQGRSRGGAR
                     SPARRSSSGFYSNRRRPGGSSPRPLFGGIFISDFGGGGGFSNKTQMPLSSSGGSPDSG
                     SFNPPPDRDRGPDGQGMCRENRRENGGIPGWYMVLMAIMVIFSAMLFWNAAQARSDAA
                     GHPVREKLAESACITEDVWINDSLDWLGNDTSVRKAMKYFQEKTGIQPYLFITDNLDG
                     KGGEITDKEAETYLADLYDSLYSDEGHMIFTFMEYAPSQYVTYLYTGTAADSVMDTDA
                     RNLFLDCADRYYADSSLSDAEFFEKVFVKAADQIMEDTAGHARAAVLYAVCGAAVLLV
                     MAAGLILFKIQEKKAAEAETLKKILDTPVGLSSEEEELKNKYSE"
     gene            12369..13808
                     /locus_tag="ACZPCR_07100"
     CDS             12369..13808
                     /locus_tag="ACZPCR_07100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008398318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HIR1230681.1"
                     /translation="MPDAAVITPLHVLYLAGVISILAVMIMRLDTPLVCIFFLFLIGA
                     VGLGSVVGGIQTVFNASLFAAREFMEIIATIALVTALSKCLGELGSDQLIAAPVKRVM
                     KTPSAAWWTLGIFMFLVSLFLWPSPAVALVGAVLLPVTLKAGLSPLLAAMAMNLFGHG
                     FALSWDAVIQGAPAVSASAAGISASLLLTEAGPVFLTMGIVTALAAFILNKKEISGQS
                     AAARKAGGILSGSRQESDQREKQQSGKEPGESLPDRSRKSAAAIMAVLVPLAFLTDIL
                     IMLSRNLSGGEATSIVSGTAAALMCLGSVLGFGRRSLKKVTSYLTDGFLFAIQIFAPV
                     IVIGAFFFLGGNGITSILGEKFQTGILNDWAVWLASHAPLNAHMAAFLQIIIGGLTGL
                     DGSGFSGLPLTGAMARTFGAATGASVPVLAALGQISAIYVGGGTIVPWGIIPVAAICG
                     VSPVDLARKNLLPVAAGFLAAFLAACFLL"
     gene            13876..15741
                     /gene="asnB"
                     /locus_tag="ACZPCR_07105"
     CDS             13876..15741
                     /gene="asnB"
                     /locus_tag="ACZPCR_07105"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0070981 - L-asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HIR1230682.1"
                     /translation="MNKIAGFYSLEQDLSEKKSDSENLLKKMKEAQEPSRRKKGMLCS
                     TENEAAQKEESEYLNSRFGLIRTGRLSVRPKDGADACVLYSGEIYNWKELCKELSDWG
                     FPEPKDEADALLIAYLAWGPDFIKKVNGCFSIAVADEKENRLLLYRDRAGTRPLFYTV
                     NPEKLLCFSSSLKALLACPGIRPQVDLGSLNEIFSIGPARTPGCGVYKNISEVLPGCF
                     LCASPAGIQLHDYWKLKAEPHTDSYEETIEKTKALIEDSVRRQMRPEMPFCTFLSGGL
                     DSSLISALCARELKKQNRQLTTYSFDFVGNDKNFQSNAFQPSQDRPYVEKMAAFLETD
                     HHFLECSTKTQTEYLKESVKAHGLPAMADVDSSLLYFCSQVGERYEAALTGECADEIF
                     GGYPWFHREELMMADTFPWTIDLAPRKLLLSDEFAEALSMEEYVQNAYEASLARMPRL
                     EGETGLNAKRREISWLNLQWFMETLLNRMDRTSGACGLTARVPFADFRIVEYLYNVPW
                     EMKAKNGVIKGLLRDTGRGLLPDEVLFRRKSPYPKTYDRAYETLLASQMRELLHDSSS
                     PLLPLLDKTKTEQFLESPSDYGRPWYGQLMAGPQLIAYLLQIDFWMREYQVELLL"
     gene            complement(15818..17047)
                     /gene="pepT"
                     /locus_tag="ACZPCR_07110"
     CDS             complement(15818..17047)
                     /gene="pepT"
                     /locus_tag="ACZPCR_07110"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HIR1230683.1"
                     /translation="MSKVLDRFLHYVSFDTQSMDDQEQVPSTEKQLTLAKALKEELEA
                     MGASQVRMSEHGYVYAVIPATADHPVRSLGFVAHMDTAPAMSGKNVKPRIVERYDGQD
                     LVLNEEKKIVMRVKDFPGMLDCVGKDLIVTDGTTLLGADDKAGIAEIMTMAEFFLSHP
                     EIPHGKICISFTPDEEVGRGADFFDVEHFGAEAAYTVDGGPVGELEYENFNAASGKVD
                     ICGRGVHPGSAKGAMVNALLVGMEFQSMLPAFENPMYTEGYEGFFHLDQMAGDVESAH
                     LEYIIRDHDRKAFEKKKALFEEVSRYLNVKYGEGTVLTAVKDSYYNMKEQIEPDHLYL
                     IDTAKEAMKSLDIKPLVSPIRGGTDGARLSYMGLPCPNLSTGGYNFHGRYEFIPVQSL
                     EQMVEVLKKIVTLFEEM"
     gene            complement(17142..17678)
                     /locus_tag="ACZPCR_07115"
     CDS             complement(17142..17678)
                     /locus_tag="ACZPCR_07115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004462427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HIR1230684.1"
                     /translation="MGTWKTRGLRGSTLEDLINRTNDSYREKGLALIQKVPTPITPIS
                     IDKESRHITLAYFDQKSTVDYIGAVQGIPVCFDAKECAASTFPLQNLHPHQVAFMREF
                     EQQGGVSFILVSYTGLEEMYYVPFRHVEKFWRRMEEGGRKSFTYDEVDKAFRVRAFRE
                     FFVHYLEAMQRDLELRED"
     gene            complement(17679..18653)
                     /locus_tag="ACZPCR_07120"
     CDS             complement(17679..18653)
                     /locus_tag="ACZPCR_07120"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004462424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HIR1230685.1"
                     /translation="MRLVTVTKNEAGQRLDKLMFKYMNLAGKSFIYKMIRKKNITLNG
                     KKCDGSEKLAEGDEIRLFLAEETIEKFSEVKIQKVKKTALDIVYEDKDVIFINKPAGM
                     LSQKAKDSDESLVEYLIDYLLGSGQLSREELKSFRPSVCNRLDRNTSGLVAAGKSLLG
                     LQVLSKAIKERTIGKYYLCIVKGVIDSPRRIQGWLLKNEKTNQVTVTKQRREGSLPIE
                     TEYVPMASDGHYTLLKVKLITGRSHQIRAHLASIGHPIIGDTKYGDPRENLAAKKKYG
                     VSCQLLHAALLVLPEELPEELSRLRGMEVSAPLPDVFAAFAGQLQGGR"
     gene            complement(18653..19222)
                     /locus_tag="ACZPCR_07125"
     CDS             complement(18653..19222)
                     /locus_tag="ACZPCR_07125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-linked GlcNAc transferase-like protein"
                     /protein_id="HIR1230686.1"
                     /translation="MKRIKKGEYGYRNSMRRGRVMKIAVLTLFILAQLGARWFTDSTA
                     LKNILTVMAVITVIPAANLASPYIAVFPFKTPSREFYEKLSPYESKFTILYDLVLTTK
                     DDVLPMDAIVVHPTGIYAYCVNKKAKLPRAEKAINEILTAQRLDPNMKITGELSSFEK
                     RVKSLKAASEYEDDGSVEYAVTVMKGLSM"
     gene            complement(19209..20057)
                     /locus_tag="ACZPCR_07130"
     CDS             complement(19209..20057)
                     /locus_tag="ACZPCR_07130"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070401 - NADP+ binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HIR1230687.1"
                     /translation="MKKIAVVTGASSGMGREAAVQLADQFGWLDEIWLIARREERLSR
                     LRKELPCPSRIFELDLTKQTALSALSAALEEEQPRIVFLVNAAGYGKIGQVGEVSLSE
                     EMGMPDLNCAALTGVTHLALPYMGANSRILQFASSAAFLPQPGFAVYAATKAFVLSYS
                     RALGEEVKKRGIYVTAVCPGPVKTEFFDIAQTTGSIPLYKALAMADPKKVVKLAIRDS
                     VMKKSVSVYGPLMKLFRLASKALPHSFLLSLMSVLSPEQTVQESGNTQAHPINKYAGE
                     QTYETN"
     gene            complement(20100..22046)
                     /locus_tag="ACZPCR_07135"
     CDS             complement(20100..22046)
                     /locus_tag="ACZPCR_07135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HIR1230688.1"
                     /translation="MIHDYLPICREDMEKRGWDQCDFVYVTGDAYVDHPSFGHAIISR
                     VLESHGYRVGIIPQPDWKNPESIQILGEPRLAFLISAGNMDSMVNHYSVSKKRRAKDS
                     YTPGGEMGKRPDYATVVYGNLIRSVYKKTPIVIGGIEASLRRLAHYDYWSGRLKRSIL
                     LDSQADLISYGMGERSIVEIADALNSGIDVKDITFIDGTVYKAENLDSVYDELRLPSY
                     QSMKEDKREYAKSFYTQYCNTDPFVGKRLVEPYKDNLFVIQNPASKPLTQEEMDDVYA
                     LPYMRSYHPSYEAAGGVPAISEVKFSLISNRGCFGGCNFCALTFHQGRIVQTRSHDSI
                     VDEAKLLTEEPDFKGYIHDVGGPTANFRFPACEKQMTAGVCPERQCLFPKPCRNLRAD
                     HKDYIALLRRLRDIPKVKKVFIRSGIRFDYLLADPSREFLKELCQYHVSGQLKVAPEH
                     VADNVLKRMGKPESSVYRQFMKEYKDMNERLGLKQYLVPYLMSSHPGSTLTEAVELAE
                     YLRDLGYMPEQVQDFYPTPSTISTCMYYTGLDPKTLTPVYVPTNPHEKAMQRALIQYR
                     NPKNYDLVEEALKKAGRTDLIGYDKKCLIRPRRNEHRGPGGQEFYGNKSGLGKGQGKG
                     AAGQGSGRQPKKKKTIRNVHKKRS"
     gene            complement(22082..22726)
                     /locus_tag="ACZPCR_07140"
     CDS             complement(22082..22726)
                     /locus_tag="ACZPCR_07140"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HIR1230689.1"
                     /translation="MTGKKAFLFDLDGTLVDSMWMWGAIDVEYLGKFGLTCPPDLQKA
                     IEGMSFSETAAYFKKRFALEASLEEIKADWISMSIEKYRSQVPPKPGTEAFLSWAAKQ
                     NIKMAVCTSNGREMVDAVLSSLNLARYFDCIITGCEVAAGKPSPDIYLEAARRMKVSP
                     EECAVFEDVPAGILAGKRAGMEVFAVEDEYSLGMEEKKRALSDFYIRDYRELTP"
     gene            complement(22763..23470)
                     /locus_tag="ACZPCR_07145"
                     /pseudo
     CDS             complement(22763..23470)
                     /locus_tag="ACZPCR_07145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013272637.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
     gene            complement(23470..24933)
                     /locus_tag="ACZPCR_07150"
     CDS             complement(23470..24933)
                     /locus_tag="ACZPCR_07150"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HIR1230690.1"
                     /translation="MKKNREPGTLPADFKEKMKLLLGDEYEAYVKSFEEPCHNGLRIN
                     RLKIDKETWKQIAPFSIKPVPWIENGFYYASDDEASEAEIRPSKHPWYYAGLYYLQEP
                     SAMTPASLLPVVPGDRVLDLCAAPGGKSTELGAKLQGKGLLFSNDISNSRAKALLKNL
                     EMAGISNFCVSSETPEKLSGLLLEFFDKILVDAPCSGEGMFRRDPDMIKSYEKQGPSD
                     YVPIQRSIVSEAVNMLKPGGLLLYSTCTFDEEENEGTIRYLLERFPDMKLLELPQGEG
                     FSRGIGLPQCVRLFPHRIQGEGHFIALLQKDPKAAAEAPKEDAGSRSDDSAGKAVKIP
                     SSLEQLAGSEAAAFLSAVSREFPLSQLFEKNGSLYLLPEAVAELGERQRKSIRFLRTG
                     LLLGEIKKGRFEPSQALAMALKKEEYPAVIDFQPEDERAVRYLKGETIAVSSEEEASL
                     DSRFSWILVCTGGFPLGWAKRLKGSLKNKYYPGWRWQ"
     gene            complement(24968..25771)
                     /locus_tag="ACZPCR_07155"
     CDS             complement(24968..25771)
                     /locus_tag="ACZPCR_07155"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HIR1230691.1"
                     /translation="MIVILLLLLALFITAVTGFLFASVPLARLTPYALESDGFRAMRL
                     GESVSALDQLDPEQLAALMIQHNYDLTECTDLSYDNKILEMKKPRAYQKLADGYRTVL
                     SDLAYFPVPASIRPDTPRPVYEDGWQQKRTYGRERGHEGCDIMGTERERGFYPVVSMS
                     SGTVEKVGWLELGGWRIGIRSPSGAYLYYAHLYSYSRDWKEGDTVEAGELLGFMGDSG
                     YGREENTVGNFPVHLHLGIYIQTEHFKELSVNPYWILRYLEKRTLLYDY"
     gene            25824..26759
                     /locus_tag="ACZPCR_07160"
     CDS             25824..26759
                     /locus_tag="ACZPCR_07160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230692.1"
                     /translation="MKKSLFPSAMAAVMGLLLFCPSLALKGARSGLLLWFHTVLPTLL
                     PFMLCSSAIVAFGAVPAITCPLAPLFSRLSLSENGSYALMAGILCGYPMGPKTAADFL
                     AEEEISTEEARYLLAVSAWPSPMFLAGYLAVLLPASLSFPKVLFCVYAPIFLTAALAR
                     AVYHVPKQTCKKQNQRPAVKTSVPASTGSFDEILMDCLEIMAKIGGYLMIFSILSSFV
                     TAFSPKECFLRPYLLGLIEMTTGIREMASSCHPDLLIGAGMTGAAVFGGLSGIFQVSA
                     VIKKNAGLSIRHYVLWKLLHLLLSTVLFILLSLSD"
     gene            complement(26734..27315)
                     /locus_tag="ACZPCR_07165"
     CDS             complement(26734..27315)
                     /locus_tag="ACZPCR_07165"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit B family protein"
                     /protein_id="HIR1230693.1"
                     /translation="MSRIEQIINEIEEYIESCKFQPLSNTKILVNKEEIEELLVELRL
                     RIPEEIKKYQKIISNQDAILQEARSQADAMVAKATEQTNELVNEHEIMQRAYAEAESI
                     IQNAQTQGQAILDRAVNEANAMRQSSVQYTDDMLRSLQTIVKHTMDEAQNRFDSFASS
                     LQSSYDIVSSNRIELAGSLVEETPDPNQTGTAE"
     gene            complement(27302..27823)
                     /gene="coaD"
                     /locus_tag="ACZPCR_07170"
     CDS             complement(27302..27823)
                     /gene="coaD"
                     /locus_tag="ACZPCR_07170"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005424620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HIR1230694.1"
                     /translation="MKTAIYPGSFDPVTLGHYDIIERSSKIFDRLIVGVLNNSAKSPL
                     FSVEERVKMLKDVTKGLPNVEVMAFDGLLIDFARAKEAQVIVRGLRAVTDFEYELQMA
                     QMNRVIAPEIDTLFLTTNLKYAYLSSSISKEVAMYGGDISAFLDPLVAKEVQKKCSAS
                     HKKVKEIENYEQN"
BASE COUNT         6213 a         7575 c         6677 g         7467 t
ORIGIN      
        1 taaaagctgc tcccacacta actctcccta actcatccca acccttttca ttacacacag
       61 ctgaagtaca gggctgtgtg gtcagaattc ttacacaaga gctgggacct caccctgtag
      121 ccttctttaa taagcgcttg tttttccctt tcgctttcca caagcctttc cacattttcc
      181 cttataagcc tgaacatcat tcattccccc ttaatcgctc ggtttggcgt ccttgacgtt
      241 tacaaacagc gaacccttct tattgtcaag cacccataaa tcatggtacc gcctgtaatc
      301 tatgctccac gcgtttgcgg cctggtatgt gtccggcgta aaaatcctca ttttgtcctg
      361 ttttgtaacc gctatgggaa cattcctcgc tatggctata aagttgacgt caaggccttt
      421 ttcgcccttt ttataaccgc ccgcttcctg gcctcccgtc ttgccgtcgt aaacggtaat
      481 cgccgtgtac atcctgtttg aaggcacagc tataagcggg caaccgtcaa tctggggtac
      541 ctgcgtgttt atacccgcct gtgaaaacgt cattgccgta agctttccga gggcggcctc
      601 ctcaaccgcg cccacaacgt catatgtcgc aagtatatca atttcgccgt cgtagccgtt
      661 ttcgcgtatc cttttaaccg ccgttttaat cttttttata atactgcttc cgtcaaccgt
      721 atatccgtac tcggcctgta cgtcgccgtc aacgcccatt gccgtcgccg ctaatttcga
      781 aatacggtat gcgtcaattt ccggcacaag cattgtgcgc tggaactcgc ccataacgtt
      841 gcccgccgtg gcgagaaagt tggattcgtc tacgtccatg gcgtcaatca tgaatttcct
      901 gcccctgtcc tgggtcattt ttaacgtctg gtatgaaagg tttaccgcgc ctcttacata
      961 tccttcctcc cttgaatagt tgcccaaccc ctgcaccgaa agtttgggaa ccttaacctc
     1021 gtcgccgccg ctgtagcgca cctgtccgct gtttgcgtcc ataaagcccg tttttaaagt
     1081 ctgcaccgca agcaggtcaa gatttgtttc aaatagtttt gcatactcca atacgtttac
     1141 cgccataata ttttacctcc ttatataatt cccatggctt ttgctattac gtcgttcagg
     1201 ttttccgctc cgtccgccgc cctgcccgcg gcaacgccgt tcccttcggt tgtaacggtt
     1261 tcgacgttga acagatagcc gtcggtttcc ttaatctttt caatatcaag gccttcaata
     1321 gtcccgtcgt ctttaacggt tactttgtcc atgtctataa gcgccttaac ggctttcgcg
     1381 ttgcgcgccc ccgccttcat aaccgccata tccacggcgg ccgctttctt taatgcccgc
     1441 atatcgttat tgtatttcgt ttcccatgat ttgacgtccg ctttaagtcc ttcaacgtcc
     1501 acgccgtcaa agcccttaag tttccccgtc aattccctta tgctttcgtt cgcggcttta
     1561 agttcgcgtt ctttcgcctc aaggtcccct tgtctggcgt agcctgacga aacatccgca
     1621 agcttaatgc ccgccccgtt tacggccgtt tcaagctcct catatgtgag ggccttgccg
     1681 tcgaacagct tttttaaaaa ttccattcct tttccccctt tttttgtttg cattaaaaaa
     1741 gcgcttatct gatgataaac gctttaaaat attattagat attggttttc tctcacggct
     1801 gtggtaatcc ctggttccga tggcagaacc ggattgtata aaatatacat agtcaggaaa
     1861 atctcccagg ctgatgataa cagagcctgc gggataaaca agctgcactc cctgagtttt
     1921 tatttcctcc gacagaactg aaacattaaa ctggttgtaa gagtcatatt ttttccatag
     1981 ctcccgcagg ttcatcatat cctccctgtc atccaatcac agtgtctgtt aaacaatcaa
     2041 aacatctttg actccggcct tcagcgctgt atcacgaaga agtttcatat aggcatcgtc
     2101 aggttctctt gtggatgaaa aattttctcg gacgccatag tgccggaact taattaattt
     2161 ataccgcaca ttgggataat ttgcaatcag attgcttccc agctcaaccg ttttcaggtt
     2221 atctactgca tctggaacga ctacggttct gatttcatag agcttatcca tagccgccat
     2281 acggcggata ttttcggcca caacggaaag gccccttccg gtgaggtgga gatgatcctc
     2341 ctcgcttcct gcctttaaat cgatcatggt tttatcggtt acttccagca cgtcctctct
     2401 ctcccaaaga ggaatctgtc cattggtgtc cataaacgta gtttttccgg ctgcctgaac
     2461 cagggtatag aattctttta gaaaatcaag atagaggctg cattctccgc ctgaggtagt
     2521 gatgccgttt acgaagggga aaaagccgcg tatttcctca tacagctgtc cggctgtcat
     2581 gtttcgtatc ttgggggagg cgtcaaactg acaggttttt aagcaggtat cgcagttaca
     2641 gcattttgaa taatcatagg agacccttcc gttttccatc ataagcgcgc ctgcgggaca
     2701 tgtgtttaca catgccccgc agtttctgca catatggatg gtctccggat tgtggcagta
     2761 gagacagttc tgattgcagc cctgaagaaa gactgcagta cggtttccaa agccgtctac
     2821 actgctgaaa ggaataattt tattaaccgg agccttaaga tccattagtt tccacgcacc
     2881 tttctgtcaa gaagatgaag atttttatca accacagcgc cgtttacagt ggcttcgttt
     2941 aaagtcatct gctctttatt aaacttttca atgtcagagc gttttaccag gtatcctgtg
     3001 acgcgcacca ggtcggaatc tccggaatag aaggagagat atctggctcc tgtggagaaa
     3061 gcgcccttta aaatgtcaag cagatactga ggattgtttc ccactgtgtg atcaaaaggg
     3121 aacagctctc cacagccggc atcgcagccc ttatgcatac gggtaaaatg ctgaatctga
     3181 agcggaagct ccggctcctc tccgatagga attcggccgc ctggagtaga ttccgtatcc
     3241 tccatcacgc cgacctgggc gtgaagaccg tattttccat aggccgccgg acgtttgtca
     3301 atctctgcac ggatgcggtc cataatcgcc tcgccaaagg cgtctgcttt ttcattatgt
     3361 ccgtagcgct ctcccggctc tgtgagtccc agggccttgt ttacgcactc tgccaggccc
     3421 acaaaaccga acatgccgat catatagtcc ttttccttgc ggatcaggcc ttcccggtag
     3481 agaaagttat tttcataata atggcactcg tccacgataa aacggcagcg gctgtcgatg
     3541 gcgtcgcaga cggctgtcac agcgtcaggg atgacacggt ctaagagatc ttccggactt
     3601 tttgccagct ctggaagacg gttcatattc agacgtacca gagtcaggcc gcagcctccg
     3661 ataggcagcg tgttgtagca gctgacaact gcatagtctc ccatttcttt ccgatacatt
     3721 ttatcattgg caaagcttgg cttggctgct gccatggctg tgtccagagc cgccagcata
     3781 aagctgtccg gtgtgtcatc tctgtagaga agcgtcatat tcgggcaggg ccgctgcatt
     3841 tcttttgtca gttttaagac aatgcgtccg gcttttgtat cctccggtcc caggtttgca
     3901 tgacagaaag cgttggaaat cgttctgtct acatggacta acagaaaacg aatcgctttc
     3961 tcagcttcag cctcatcggt tacaaacgga tccagaagag ttcccagatt tccgatgtaa
     4021 acaggaagcc cgccgtctgc cgggatgtta tggtacaggc agaggagatt tcccactgcg
     4081 tcccagatat ccttaggcgg ctccagcata agaaattcgc tgccctgttt taagaatttt
     4141 tcgtagtccg gcacgcagta gcgtgtgcgg tagggagttt ttccttcgaa catatccatc
     4201 atggcgccgt ttgcaaagta ttcctttgat ttttcggtat actctaccag ctcgatggaa
     4261 ttttccgcga tctttgccat atcctttaat ctctgattaa aggtaacctt aggatttttg
     4321 atggtgtaca ggatatcgtt tgtcatatca aaagatgcca tgtcagtcct cctttttact
     4381 gtttgagcgc ttatgctcgt ttcatttttc tgcaggctct gatagagaag acagccagac
     4441 caatgagggt tgcacagtat ggaatggtct taaccagatc ggacggccat cccagggttg
     4501 ccactgcgtt tgacagggcg tccgccacac cgaacaggag ggaagtggcg gctgtgccga
     4561 ctgcgcctct ctggcccatg gcttcagctg ccaaggcaat ccatccgcgg ccgctgacca
     4621 tatctctgga gaaccaggat acataaccca tggacataaa agctccgcca aggccgctca
     4681 taacgccgct gatcaacagt gcagctgcct gagtcttcat cacactgatg cccacagaat
     4741 ccgctgcctc ttttttctct ccgactgcac ggatgtggta tccaagtgat gttttcttca
     4801 gaagcaggta agtaaatacc actgccagaa ttgacaggta ggtaagtacg ttgtggccgg
     4861 atatggccgg tccgataatc ggaatctgct cgataatcgg gatattgatg tttggcagca
     4921 ccttactggt gagggctacg ctggtaccct tgtcatgagc caccagatag aggaagaaaa
     4981 tggttcctcc gctggccagg ctgttaatgg caatgccgcc taagataata ttggttttgt
     5041 agtacagagt aaagaaggcc agaattcctg ccgccagcac ggcgaagaga atggcgaaag
     5101 ccagtccggc ccaggcactt ccaaacaggt agctgaagta cattcccgca aaagcggcga
     5161 tcagcatcat gccctccagg gcaatattgg gaacaccggc cacgtcagac acaactgcgc
     5221 ccatagaggc aaacagaagg ggtgtggcta cacgaaaaat ggagtaaaaa aagtcactgg
     5281 taaaaatcag gtctgcaagc gctttcatcc cttcacctcc ttctcaatcc agttctgttt
     5341 atatttgtgc aggaatcgtt ctgctgaaat taagagaatg ataatactct gaagaatcgc
     5401 tatcatctct gtaggaatat cagaggaacg gttcacaagg tctgctccga ttctcaggta
     5461 gctgacaaag aaagccgccc cgatgacacc taaggggtta tttcccgcca gcatggcgat
     5521 catggctccg tcgaaaccgt agcctggaag agctgtccac tcgaaccgtt tgtgcatgcc
     5581 gatgcactcg atcagtcctc cggctccggc aatagcgcct gctgccagat ggacgataat
     5641 aatcactttt gttacattaa ttccggaata gctggcaaat ttagcattat ttccagtcat
     5701 acggatttcg tatccccatt tacttttgaa cataaacaga tatactaaga cagcgcataa
     5761 aactgcaatc agaaaaccgg aatgaattct ggttccaggt acaatattgg aaagaagggc
     5821 attggagcgg tatttgtagg ataccaggga cgctaccttc ggatcgcgca tcacattgtt
     5881 taagagatag agtcccactc ccagaagaat gttgttcatc atcagagaag ttaccatctc
     5941 gttggcaccg tattttgcct tcagaacacc gggaaccagc ataattatca taccggctaa
     6001 agctcctgct gcaatgcagg caataggaaa tacgatggga ggcattttca gccagattgc
     6061 caggaaggat ccggcgattc cggaaataaa aaagacgccc tctccgccca gattaaacag
     6121 gttggcttta aacatgactg ccatagccag accagagaaa ataagcggaa ctgctgtttc
     6181 cacaatattt cccagatatc gtttagaaga aaacggcgct aacaggaagg ttttaatgga
     6241 ttccaccggc tgatcgctga ctaacagaat gatgacaaag gccaccagga ttgctaccag
     6301 catggaaacg gcggttctta tgatgttaaa ggaacgctct ctgctcatcc ttctgccctc
     6361 cttatctgtt cttcgctgtg cttttccagt cccagcatgt aaagtcccag cttctcttcg
     6421 ttcagtcctt ctgtattatc gaaataagcc acaatttctc cttcatacat aacggcaatc
     6481 acatcggaga gctttaatgc ttcgcttaaa tcagcagaga ttaaaagcac cgcacagccc
     6541 tgatccctca gctccatcat ttttttatgg ataatgtggg cagctccgat atcgacacct
     6601 ctggtaggct gttctgcaat cagaacttct gggttgtggc tgcactctct ggctacgact
     6661 actttctgca tatttccgcc ggacagcatt cccacattct gtcccgtgcc ggaacagcgt
     6721 atttcgtagg atttaatgcg ctcctccgca aattttaata tctttttata gttcagaagg
     6781 ccgccgcggc agaattcctt gctgccgtac cggttggaaa ccatgttttc tgcaatggat
     6841 tcctggcctg cgatgccctg ctccatacgg tcctccggca catagccgaa ctgcatgttc
     6901 cggatctgtt caatggacag attcttcacg gacgttccgt ttaaaagaat atctccatct
     6961 tttatcatcc tctttttcgt catcagttct accagctcca cctggccgtt tccctggacg
     7021 ccggcaattc caaaaatcat gccgcccctg actccgaaat taatgttgtt cagcagtttc
     7081 acctggtttt tatctgtgta ggacaggttt ttaacctgaa ttttcacatc gcctggcttg
     7141 gggactgtct tctgaatgga agtatccatt tcacagccca tgatcatggc tgaaatctcc
     7201 tgctctgtca catcctttgt ctcgcagcag cctacaaact ggctggctct catgacagta
     7261 atgcggtcgg aaatacgctt gatttccgga attttatggg aaatgaacac aatggtgtgt
     7321 ccctgctttt tcagattaat aagctcgtcg aagagctggt ctgtttcctg gggagccagc
     7381 acggcggtgg gctcgtccag aatcaggatc tctgcgcctc tggccagagc cttcaaaatt
     7441 tcaattttct gttttacgcc tacgggaaga gtctgtgtaa ccgcttccgc gtctacgtcc
     7501 agattatact ttttactgat ttcctttgta aagcggatcg cttcctcctc gctgacaaaa
     7561 agcccctttt tcggttccat gccgaggata atgttctggg ccgctgtaaa ggattccacc
     7621 agcataaagt gctgatgcac cattccgatt ccatgagcga tggcatcctt agaggaggag
     7681 aacctgacag gttctcccct caagatgatc tctcctgatg acggcggttc cattccgaat
     7741 aagattttca tcagggtaga ttttccagct ccgttttctc ctaccagagc atgaatctct
     7801 ccctttttca gattgaaatt aacattttta ttcgctgcaa tcccgttgct ataaattttt
     7861 gagatgttgt tcatctctaa aagatactgt tccatcagga tacctccgtg aactatgggc
     7921 gtacagcctc gcggatttca ttcactttct ctgtagtaat tccagtagtt ggagtcattt
     7981 cgatttctcc ggcaactacc tgtcctttta actcctcgat tttcgctctg tcctcctcag
     8041 acagtaaagc ctcatagaat tcgttctcag cgatgccaac agcgtcctcg gcgattccga
     8101 atacttctct tgtgccgtaa ggaatctcgc ctttcatggc tctgtctact gcctttacgg
     8161 cgttctccgg gatattcttg atagcggagg tgataatcac gcctgccatc tccggctttg
     8221 tctcctttaa ggcctctgcc tggtcagagt caacgccgat agcgaacttg ttctgagcta
     8281 cagccgcgtc aattacgcca agaccggact gtcctgctgc cgcgaagata acagaaagac
     8341 cggaattgta gagaagaaga gcgttctctt ttcccttggc tgtgtcagtg aagcttccca
     8401 cataggatgt cgctaccttg atatccggat taacagcctg ggcgccctcg atgtatccca
     8461 ctaagaactc gttgattcca gggatatcca tgccgcctac gaagccgatt ttgtcctctc
     8521 ccagctctgc tgccttgaga gctgcggctg caccggccag gaaactcatc tcgttgtttt
     8581 ttgtacccat gatatatacg tttgcaggcg gatcggtcag ctcatcgtcc agattgatga
     8641 acagctgatc cggatactcc tctgctgcct gaactagggc gtcgtcgttg ttgctggaaa
     8701 tcgttaagat taagtcataa tcagcctcgc acatatctac gagaaccggg taatacttag
     8761 atgtgtccag tccggcctcc acgtagtcta ccgttacgcc aagctgctcc tcaataggct
     8821 caatggcgcg gaaggaagcg tcaaaaaatg atttgtctcc caggtttcca ggaatcataa
     8881 gagctacctt gtagtcctcc ggatttactg cctctgcgtc tccctctccc tgcgcttctg
     8941 ctgcgctctc agcggccttg gacggcgctg tggtctcctc cggatccggc gcagagcatc
     9001 ctgtcatcat gcccgcagtc atgcatacgg caagggccgc tgctgtcagt ttcttcatag
     9061 tgattgtcct cctcataatc gttttctcta tcgaaagccc tctggctttt gattaaaata
     9121 acactcagct gaaataaaat taaaaatact gttccagaat ctgaaagaac cggtttgtat
     9181 ccacatggac ggcaaactga agacgtccct cctctgggga gtgaatttca tagtaattgg
     9241 aaaggctgac cagagttccg cgggtcatag agccgcttaa ctcaactgtg taatcgcccc
     9301 gctgcaggga aactgtctcc ggatccagca ggtaagcgac taaaagcaca tcgtgaaacg
     9361 tgaccggaaa gccagtggcc ttctgaaaca gggaaactcc ctccagaaag taatccatag
     9421 ccggatcttt tcgttttctc cagccgtcaa gcatttccgg gcttattctc agatatttcg
     9481 tcacgtccag ccccatcatg atcaggttct cagactgttc catcacaagt ctggccgcct
     9541 ccgggtcgca ggcaatattc cactcaggct ttgcgtcgaa aaaggcgcct cccatggcga
     9601 gaatttttac atggcgcatc agctccggtt ccctgagaaa ggccatggcc agattcgtca
     9661 tggatcccat agctaagata acaaggtctg gatgctctct gacgcactgg atgattaagt
     9721 cctccgccgg acgatcagac agcaggccag tcttgttttt taaaacaggg tactggatag
     9781 gctccggccc ggcgctgtgg gcccgttcaa tgagagcttt ttcgtgccct gccgctgcgg
     9841 gaatatcatg tctgccgtaa aggcttaaaa attccagcac catctcagcg cgctttttcg
     9901 tgtctccgaa tacggttgtc acagctgcga tatccagaca gccgcaggaa agagccaggc
     9961 ggaaagccgc cgcatcgtcg gtgtcgtctc cgaaatctgt gtcgattaat atggttgtct
    10021 ttttcattct ctctgttccg ttcataaaaa taaagcaata ggctgtactg cttttgcaga
    10081 ttcattatat aaggaaacca taaacaggaa aaggacattt gtccttttgt tggccagatt
    10141 ttgtgagttt ttgtaaaaat ttctggttat aatccatgaa tattagtgaa actaatgaaa
    10201 tttcattaaa aaaactaatc aagccattct atatcacgtc ctgctgtata gaagaagcca
    10261 atccgtttcc gaactggctt cgcaggcgtc tctattctat tttcatgaag cagaatgctt
    10321 ttttcacgtt tttaaagcgg gatgaggcta cagtcccagc tctgccttca gcttttctaa
    10381 agctagatct gcgtcagaag gactggctcc cccgtatttt ttcatcagat cctcagcctc
    10441 cgcttcctcg ctgcctgcgc tcagagcctc ggacgcctgg gctctggcaa gctctcggtc
    10501 cgctttttct tccattctgg cgaaggcgtc aaacgcccct ctgtctgtat ctctggaggt
    10561 gagctcagcg gcttttttcg tcactttggc cgttacggct ttcgccttaa tctgagcggc
    10621 cttctgcttc atatcgttaa tctcgccctc catctgtctc agcttgcccc gtacagtatc
    10681 cgccgcctgc ctggcagcct cataagcagc ttcctgggaa gcggcgcgtg tctggcagtc
    10741 gttttccttt tctaacgcct ttttggcgtc agcctcattt ccggccgtta atgccttcac
    10801 tgcaatggaa tgccaggttt cagcctcctt tttcagctca tccagctgct ttttagtaag
    10861 ggtttcattg gccagcacgt ctaaggccgt ttttttcatg tttccgtatt cctgaaccgc
    10921 gtcaatgatg gtctgatcga tgatcttttc tggatcctca aacttatcaa gaagctcgtt
    10981 cagatttgat tttactatca ttccaattct gtcaaaaatt ccagccatag ctgtattcct
    11041 ccttacatgc ttactcgcta tatttgttct tcagctcctc ctcttccgaa gataagccga
    11101 caggcgtatc taaaatcttc ttcagagtct ctgcttcagc tgcctttttc tcctgtattt
    11161 tgaaaagaat cagccctgcc gccatgacaa gcaggacggc cgctccgcac acggcgtata
    11221 atactgcggc tctcgcatgg cccgccgtgt cctccataat ctgatcagcg gcttttacaa
    11281 agaccttttc aaagaactct gcgtctgaca gagagctgtc cgcgtaataa cggtccgcac
    11341 agtccagaaa cagattccgc gcgtcggtgt ccatcacgct gtcggcagcc gttccggtat
    11401 acaggtaagt gacgtactgg gatggcgcgt actccataaa ggtaaaaatc atatgcccct
    11461 cgtcggaata gagagaatca tacaggtctg caagataggt ttctgcctct ttgtctgtta
    11521 tctccccgcc ctttccatcc agattgtccg taatgaaaag gtagggctga ataccggtct
    11581 tctcctgaaa atacttcatg gccttcctga cagaggtatc gtttcccagc cagtctaaag
    11641 aatcgttgat ccagacgtct tccgttatgc aggcgctttc tgccagcttc tcccgcactg
    11701 gatgcccggc tgcgtccgat ctggcctgag ccgcattcca gaacagcatg gcggagaaga
    11761 taaccataat ggccataaga accatgtacc atccgggaat accgccgttc tctctcctgt
    11821 tctcccggca cattccctgg ccgtctggcc cgcgatccct gtcaggcggc ggattaaagg
    11881 atccgctgtc cggggagccg ccagaggaag aaagaggcat ctgcgttttg tttgaaaagc
    11941 cgcctccccc tccgaagtcg gaaataaaaa ttccgccgaa caatggccgc ggggacgaac
    12001 ctccaggccg cctgcggttt gaataaaatc cgctggagct gcgtctggcc gggcttcgcg
    12061 ctcctcctct ggaacgtccc tggcctgcgg agcgtctgct ggaaaatccc ctgctgcccc
    12121 ctctggaaaa tcctccggaa cgccctcccg aacgtccgcc gccggagcgg cctcctcctc
    12181 ttcccatatg ttttcctccg tacatgatag aattaattgg atagaaataa agtcagacga
    12241 ttataaaaac tatctattaa attatagacg aaagccgggg ttccggcaat aaaaactggc
    12301 acaattttca agaaaacctg tccccgcgca tacattacgg tatatcctta cagacaggag
    12361 gcctatgtat gcctgacgca gcagtgatta ctccccttca cgttctctat ctggcgggag
    12421 taatttctat ccttgcagtt atgatcatgc ggcttgacac gccgcttgta tgtattttct
    12481 ttctgttttt aataggagcc gttggacttg gttccgttgt aggcggcatt cagaccgtgt
    12541 tcaacgcatc gcttttcgca gcccgcgagt ttatggagat tatcgctacc attgccctgg
    12601 taacggcttt atcgaaatgc ctgggggagc tgggaagcga tcagctgata gcggctccgg
    12661 taaagcgcgt catgaaaact ccctcagccg cctggtggac gctgggaatt ttcatgtttt
    12721 tagtctcgct gtttttatgg ccctccccgg cagtggctct tgtgggagcc gttctgcttc
    12781 cggtaacctt aaaggcaggc ctctccccgc ttctggcggc tatggccatg aatttatttg
    12841 gccatggctt tgccttaagc tgggacgccg tgatccaggg cgcgcccgct gtctccgcct
    12901 cagccgccgg gatctccgcc tctcttctgc tgacagaagc cgggccggtc tttctcacca
    12961 tgggaattgt gacagctctg gcggcgttta ttttaaataa aaaagagatt tccggacaga
    13021 gcgccgcagc ccgaaaagct ggcggcattc tttcgggaag cagacaggaa agcgatcaaa
    13081 gggagaaaca gcagagtggg aaggagccag gcgagagcct gccggacaga agcaggaaat
    13141 ctgcggccgc gataatggcc gttctggttc ctcttgcatt cctgaccgat attctcatca
    13201 tgctctccag aaatttaagc ggcggggagg ctaccagcat tgtctccgga acggcggcag
    13261 cgctgatgtg cctggggtcc gtgctgggct ttggacgccg ttctctgaaa aaggtcacct
    13321 cttacctgac agacggattt ttgttcgcta tacagatttt cgctcctgtc attgtaatcg
    13381 gagccttttt ctttctggga ggaaacggca tcacctccat tttaggcgag aagtttcaga
    13441 caggaatctt aaatgactgg gccgtctggc tggcttccca tgcgccatta aacgcgcata
    13501 tggcggcgtt tctccagatt ataatcggag gactgacagg actggacgga tccggatttt
    13561 ccggacttcc tctgacaggg gccatggcca gaacctttgg agcggccaca ggggcctctg
    13621 tgcccgtgtt agcggctctg ggacaaattt cagccatcta tgtgggaggc ggaaccatcg
    13681 tgccatgggg aattatcccg gttgccgcca tctgcggagt cagcccggtg gatctggcaa
    13741 gaaagaatct gcttcccgtg gcagccggat ttctggcggc ctttctggca gcctgctttc
    13801 tgctctagga gctggcagcc gcgtccccat tacagtaact caacacagcc atatggcaga
    13861 aggagggctt tcaatatgaa taaaatagcg ggcttttaca gcctggaaca ggatttatcg
    13921 gagaaaaaga gtgattcaga gaacctgtta aagaaaatga aagaagcgca ggagccgtcc
    13981 cggcggaaaa aaggaatgct ttgcagcacg gaaaacgagg cagcccaaaa ggaggaatca
    14041 gaatatctca acagccgctt cggcctgatc cgcaccggca ggctttctgt ccggccaaag
    14101 gacggcgcgg atgcatgcgt gctgtacagc ggagaaatct acaattggaa agagctctgc
    14161 aaagagctgt ctgactgggg ctttcctgag ccgaaggacg aggcagatgc gcttcttatt
    14221 gcctatctgg cctggggccc tgactttatc aaaaaggtaa acggctgctt ttccattgca
    14281 gtggcagatg aaaaggaaaa ccggctgctg ctctacagag acagagccgg aaccaggccg
    14341 ctgttttaca cagtgaaccc agaaaagctt ctgtgctttt cctcctctct gaaggcgctc
    14401 ttagcctgcc cgggaatcag gccccaggta gaccttggaa gcctcaacga gatcttcagc
    14461 atcggccctg ccagaacgcc tggctgtggc gtctacaaaa atatcagcga ggtgcttccc
    14521 ggctgctttc tctgcgcctc cccagccgga attcagctgc atgattactg gaagctcaag
    14581 gcggagcccc acacagactc ctacgaggag acaatagaga agacaaaggc tctgatcgag
    14641 gactccgtca ggcgtcagat gcggcctgaa atgcctttct gcactttttt gtcaggaggt
    14701 cttgattcgt ctttgatttc cgccctctgc gccagagagt taaaaaagca gaaccgccag
    14761 ctgaccacct actcctttga ctttgtgggc aacgataaaa actttcagtc caatgcgttc
    14821 cagccctccc aggatcgccc ttacgtggag aaaatggcgg cctttctgga aacagaccat
    14881 cattttctgg aatgctctac aaagacacag acagaatacc tgaaggaatc cgtcaaagct
    14941 cacgggcttc cggccatggc agatgtggac tcctctcttc tctacttctg ctcccaggta
    15001 ggagaacgct atgaggccgc ccttacaggc gaatgtgccg acgagatttt cggcggatat
    15061 ccctggtttc acagagaaga actgatgatg gccgatacct tcccatggac catagacctg
    15121 gctcccagaa agctcctgct ctccgatgaa tttgcagagg cgctttcaat ggaagaatat
    15181 gtacaaaacg catatgaggc atctctggcc cgtatgcccc gcctggaggg agagacaggt
    15241 cttaacgcca aaaggcggga aatcagctgg ctgaatcttc agtggtttat ggaaacgctg
    15301 ttaaacagaa tggatcgaac cagcggagcg tgcggcctga cagcccgcgt cccctttgcc
    15361 gacttccgga tcgtggaata tctttacaat gtcccgtggg agatgaaggc aaaaaacggc
    15421 gtgattaaag ggctgctccg ggacacggga cggggcctgc tgccggacga ggtacttttc
    15481 agaaggaaat cgccttatcc gaaaacctac gacagagcct acgaaacgct tctggccagt
    15541 cagatgaggg aactgctgca cgactcctcc tcccctcttc tcccgctgct ggataagacg
    15601 aaaacagaac aattcctgga gtctccttct gattatggac gtccctggta cggccagctg
    15661 atggcaggcc ctcagctgat agcctacctg ctgcagatcg atttctggat gagagaatac
    15721 caggtagagc ttctgcttta attatttctg tgctaaatta tctctgtact aaaaaagcct
    15781 gcatgtctga tgcaggcctt tttagtctaa gaatctgtta catttcctca aaaagggtta
    15841 cgattttctt taatacttct accatctgct ccagggattg gacaggaata aattcatatc
    15901 tgccgtggaa gttgtagcct ccggtggaca ggttcgggca gggaagtccc atgtaggaga
    15961 gacgtgcgcc gtctgtgcct ccgcggatcg gagatactaa aggcttgata tcaaggctct
    16021 tcatggcttc ctttgccgtg tcgatcaagt acaggtgatc cggctcaatc tgctccttca
    16081 tgttatagta ggagtccttg actgccgtca ggacagttcc ctccccgtac ttgacgttca
    16141 gatagcggga tacctcctca aacagagcct ttttcttctc gaaagccttc ctgtcgtgat
    16201 cccggataat atactccaga tgcgcgcttt ccacgtctcc ggccatctga tccaggtgga
    16261 agaagccctc gtagccctct gtatacatgg gattttcgaa ggcaggcagc atggactgga
    16321 attccattcc aactaaaagg gcgttgacca tggctccctt ggcgcttccc gggtggacgc
    16381 cgcggccgca gatatctacc tttccggaag cggcgttgaa gttttcgtac tccagctctc
    16441 ccacagggcc gccgtctacc gtgtaggcag cctctgctcc gaaatgttct acatcaaaga
    16501 aatcggcgcc tcttcccacc tcctcgtcag gggtaaagct gatgcagatt ttgccgtgtg
    16561 gaatttccgg gtgggacagg aaaaattctg ccatcgtcat aatctcggct atgcctgcct
    16621 tatcgtctgc tcccagaaga gtcgttccgt ctgtgacgat gagatccttt cccacgcagt
    16681 ccagcatacc ggggaagtcc tttacccgca tgacaatctt cttttcttcg ttcaatacta
    16741 aatcctgacc gtcatagcgc tccacaattc tgggctttac atttttgccg gacatggcgg
    16801 gagccgtatc catatgagcc acaaagccca aagacctgac cgggtgatcg gcagttgccg
    16861 gaatcacggc atatacatag ccgtgttcgc tcatgcgcac ctggctggct cccatggcct
    16921 ccagctcctc tttcaaagct ttggccaggg tcagctgttt ttccgtgctg ggaacctgct
    16981 cctggtcgtc catggactgg gtgtcaaagg aaacatagtg taaaaaacga tccaatacct
    17041 tgctcataat atcctcctgt gcttgtaagt aatcagcctg caaatcattg gcagtttact
    17101 tcttcagtta tatcatgttt tccatttatt ttccagaata tttagtcctc ccgaagctcc
    17161 aaatctctct gcatggcttc caggtagtgg acgaaaaatt cccggaaggc cctgacgcgg
    17221 aaggccttgt ccacctcgtc gtaggtgaag cttttccgcc cgccctcttc cattcgccgc
    17281 cagaatttct ccacatggcg gaagggcacg taatacatct cttccaggcc tgtgtaggag
    17341 accagaataa aggaaacgcc tccctgctgt tcaaattccc tcataaaggc aacctggtgc
    17401 gggtgaaggt tctggagggg aaaggtggat gccgcgcact ccttggcgtc aaagcagacg
    17461 ggaatgccct gcaccgcgcc tatgtagtct acggtacttt tctggtcaaa gtaggccagc
    17521 gtaatgtggc ggctttcctt gtcaatcgag atgggcgtga tgggggtggg caccttctga
    17581 atcagagcca gccccttttc ccggtagctg tcgttggtcc ggttgattaa atcctccaga
    17641 gtggagccgc gcagccctct tgttttccag gttcccatct accgtcctcc ctgaagctgc
    17701 cctgcaaagg ctgcgaagac gtctggaaga ggagccgaga cttccatgcc gcgaagacgg
    17761 gaaagctcct ctggaagctc ttctggaaga accagaaggg ctgcgtgaag cagctggcag
    17821 gagacgccgt atttcttttt cgcagccaga ttttccctcg gatctccgta ttttgtatcc
    17881 ccgataatcg ggtggccgat ggaggccaga tgagccctga tctggtggga ccgcccggta
    17941 atcagcttta ccttaagaag agtgtaatgt ccgtctgaag ccatgggaac gtactctgtc
    18001 tcaataggaa ggctgccctc ccgccgctgt tttgtcaccg tcacctggtt cgtcttttca
    18061 tttttcaaaa gccatccctg gatgcgcctg gggctgtcta tcacgccttt tacaatgcag
    18121 agataatatt ttccaatggt tctctccttg atggcctttg agagaacctg aaggcccagg
    18181 aggctctttc cggcagccac cagaccgctg gtattgcggt ccagccggtt gcagacagag
    18241 gggcggaagc tttttaactc ctccctggaa agctgtccgc tgcccagaag atagtcgatg
    18301 agatactcta ccagagattc gtcgctgtcc tttgccttct gggagagcat acccgccggc
    18361 ttattgataa agattacgtc cttatcctcg tacacaatgt caagggccgt cttttttacc
    18421 ttctgaattt ttacctcaga aaacttttcg atggtctcct ccgccagaaa cagacggatc
    18481 tcgtctccct cggcaagctt ttccgaaccg tcgcactttt ttccgttgag ggtaatgttt
    18541 ttctttcgga tcatcttata gatgaagctt ttgcccgcca gattcatgta tttgaacatc
    18601 agcttgtcca ggcgctggcc ggcctcgttt tttgttactg ttacaagtct cattacatgg
    18661 ataatccttt catcacagtg actgcgtact ctacgcttcc gtcgtcctcg tattcagaag
    18721 ccgccttcag gcttttcaca cgcttttcaa aggaagacag ctctcctgta attttcatat
    18781 tgggatccag gcgctgggca gtcagaattt cattgatggc cttttctgct ctgggaagct
    18841 ttgccttctt attgacgcag taggcgtaaa ttcctgtggg gtgcaccacg atggcgtcca
    18901 tgggcagcac atcgtccttt gtcgtcagca ccagatcata gagaatcgta aatttgctct
    18961 catagggaga gagcttttcg taaaattccc tggaaggcgt cttgaaggga aacacggcga
    19021 tgtaggggga ggccaggttg gcagccggaa tcacggtaat cacagccata acggtgagaa
    19081 tatttttcag agccgtgctg tctgtaaacc atctggcgcc cagctgggcc agaataaaga
    19141 gggtgagaac ggcgattttc ataacccgcc cccgcctcat actgtttctg tatccgtatt
    19201 cgcctttttt aattcgtttc ataggtttgt tctcctgcgt atttgttgat tggatgggcc
    19261 tgcgtattcc cgctctcctg aaccgtctgt tccggggaaa ggacagacat caaagagaga
    19321 aggaagctgt ggggaagcgc ctttgaggcc agccggaaca gtttcataag cggtccgtag
    19381 acagagacgc tttttttcat gaccgagtcc cggatagcaa gctttaccac ctttttagga
    19441 tccgccatgg ccagcgcttt gtagagagga atacttcccg tagtctgggc aatgtcaaaa
    19501 aattccgtct ttacaggtcc cgggcagacg gctgtcacgt agattccgcg ctttttgacc
    19561 tcctctccca gggcgcggct gtagctcaat acaaaggcct tggttgctgc gtagacggcg
    19621 aagccgggct ggggaaggaa ggccgcggag gaggcgaact ggagaatccg gctgttggct
    19681 cccatatagg ggagagccag gtgggtgacg cctgtgaggg cggcgcagtt taaatcaggc
    19741 atgcccattt cctctgacaa agacacctct cccacctggc cgattttgcc gtagcccgcc
    19801 gcgttgacca ggaagacgat tctgggctgc tcctcctcaa gggcggctga aagggctgaa
    19861 agggccgtct gctttgtcaa atccagctca aagattctgg acggacaggg aagctccttt
    19921 cttaaacgcg aaaggcgctc ctctctcctg gcgatcagcc agatttcgtc cagccagccg
    19981 aactgatccg ccagctgaac ggcggcctcc cgccccattc cggaggaagc tcctgttaca
    20041 actgcaattt tcttcatatg ccttctgcct ccttatttaa gctgacgggc ttttttcggt
    20101 cagctcctct ttttgtgtac gtttcggatg gttttctttt tctttggctg gcgtccgctt
    20161 ccctgtccgg cggctccttt tccctgccct ttgcctaaac cgctcttatt tccatagaat
    20221 tcctgcccgc ccgggcctct gtgctcgttt cgtctggggc ggatcaggca ctttttgtcg
    20281 tagccgatga gatcggtgcg tccggctttt ttgagggcct cttccaccag atcgtagttt
    20341 ttcggattcc tgtactggat cagcgccctc tgcatggcct tttcatgggg attcgtaggc
    20401 acgtaaacag gcgtcagggt tttcggatcc agccctgtgt aatacatgca ggtggaaatg
    20461 gtggacggcg tgggatagaa atcctgcacc tgttccggca tatagcccag atcccgcagg
    20521 tattccgcca gctccactgc ctctgtcagg gtggatcctg gatgagagct catcaggtag
    20581 ggcaccaggt actgttttaa gccaagccgc tcgttcatgt ccttatattc cttcatgaat
    20641 tgacggtaca cgctgctctc cggctttccc atccgcttca gcacgttgtc agccacatgc
    20701 tccggcgcca ccttcagctg tccgctgaca tggtactggc acagctcctt taaaaattcc
    20761 cggcttgggt ccgccagcag atagtcgaaa cggatgccgg atcggatgaa cacctttttc
    20821 accttgggga tatcgcgcag cctccgaaga agggcaatat aatccttgtg gtcagccctc
    20881 agattccggc acggctttgg aaaaaggcac tgccgctccg gacatacgcc ggctgtcatc
    20941 tgcttttcac aggccgggaa gcggaaattg gccgtagggc ctccgacgtc gtggatgtat
    21001 cccttaaaat ccggttcctc cgtgagaagc ttcgcctcgt ccacgatgga atcgtggctt
    21061 ctggtctgaa cgattctgcc ctggtggaag gtaagggcgc agaaattgca gcctccgaag
    21121 cagccacggt tgctgatcag gctgaatttc acctctgaaa tagcgggaac tccgcctgcc
    21181 gcctcatagg acggatggta gctgcgcata tagggcaggg cgtacacgtc gtccatctct
    21241 tcctgggtca ggggcttgga ggcaggattc tggatcacga acagattgtc cttgtaaggc
    21301 tccaccagac gctttcccac aaagggatcc gtattgcagt actgggtgta aaagctcttg
    21361 gcatactccc ttttatcctc tttcatgctc tggtaagagg gcaggcgcag ttcgtcgtag
    21421 acggaatcca gattctccgc cttgtaaact gtgccgtcga taaaggtgat atccttcacg
    21481 tcaatgccgc tgtttaaggc gtctgcaatc tccacgatgg atcgctctcc cattccgtag
    21541 gagatcagat cggcctggga atccaggaga atcgaccgct tgagtctgcc ggaccagtaa
    21601 tcgtagtggg ccagccttcg aagactggct tcaatgccgc caatgacaat aggcgttttt
    21661 ttgtagaccg agcggatgag attgccgtag acaacggtag cgtagtccgg ccgttttccc
    21721 atttccccgc ccggggtgta ggaatccttc gctctgcgct ttttagagac agagtagtgg
    21781 ttgaccatgg aatccatgtt tccggctgag atgagaaagg caagcctggg ctctcccaaa
    21841 atctggatgc tctccggatt tttccagtcc ggctgcggga tgattcccac ccggtagccg
    21901 tgagattcca gcacacggct gataatggca tggccgaagg aggggtggtc cacataggca
    21961 tcgcctgtca catagacgaa gtcgcattga tcccatcctc ttttttccat atcctctctg
    22021 cagattggta aataatcatg tatcataaat cctttgtact cctcctcaca ctctttggaa
    22081 tttacggcgt cagctctctg taatcgcgga tatagaagtc agagagcgct ctctttttct
    22141 cttccattcc aagggaatat tcatcctcca cggcaaatac ctccattccg gctctctttc
    22201 cagccaggat tccagccggc acgtcctcga acacggcgca ctcttcagga gagaccttca
    22261 tacgccgcgc cgcctccagg tagatatcgg gggacggttt gcctgccgcc acctcgcagc
    22321 cggtgataat gcagtcaaaa tagcgggcca gattcagaga gcttaacaca gcgtccacca
    22381 tttcacggcc attgctggtg cagacggcca tttttatgtt ttgttttgct gcccaggaca
    22441 aaaacgcctc tgttcccggc tttggaggca cctggcttct gtatttttca atggacatgg
    22501 agatccagtc tgccttgatt tcttccaggg aagcctccag ggcaaaccgc tttttaaaat
    22561 aggcggccgt ctcggaaaaa ctcattccct caatcgcctt ctggagatca gggggacatg
    22621 taagcccgaa ttttcccaag tattccacgt cgatggcgcc ccacatccac atagaatcca
    22681 ccagagttcc gtccagatca aataaaaagg cctttttgcc tgtcaggggg ctgctgtttt
    22741 ctaaagaaga gacttcctct ccctttaaag cgcgcagctc gtcgtctgtc agccttctgt
    22801 attctcccgg agccagcgtt tcgtccagca caaggcttcc catggaaagc cgtttcaggt
    22861 agatcacgcg gcagcctact gcctcgaaca tccgctttac ctggtggaat tttccttcat
    22921 ggatcgtcag gcggacctca gagacaggcc cttcttttaa gagttccagc tgggcgggaa
    22981 gcgtctttac ctctccgtcc agagtcaggc ctttcgcaaa ctgctccttc acgtcacttg
    23041 gcagtatacc ctctactctg gcaaaataca ccttatctac gtgctttttg ggagacagca
    23101 gctgatgggc cagctggccg tcgttggtaa tcaggagaag tccctctgtg tcgatatcca
    23161 gccgcccggc cgggaagaga tcctttcttc tggcgtcgcc gattaaatcc acaactgtct
    23221 gaaaacggcg gtcttctgtg gcggagacta ccccctgagg cttgttgagc ataaagtatt
    23281 caaaggaagc gtaggacacc gtctggccat ccagggagat ctgcgctcgt tccgggtcaa
    23341 acttttgttc cggttcccgc accgtccggc cgtctaccgt cacccgtccg cttttgatca
    23401 gcttttttac ctcgcttcgg cttccttttt tcatttccac cagaaatttg tcaaggcgca
    23461 tggttcccat tactgccacc tccatccagg ataatattta tttttcaggc tgccctttaa
    23521 acgcttggcc cagcccagag gaaatcctcc cgtgcagacg aggatccagg aaaaacggct
    23581 gtcaagagaa gcctcctctt cgctgcttac agcgatggtt tcgcccttta aatagcggac
    23641 agcccgttca tcctccggct gaaaatcgat cacagccgga tattcttctt ttttaagggc
    23701 catagccaga gcctgggacg gctcgaaccg tcccttcttg atttcgccaa gcagcagacc
    23761 ggttctaaga aaccggatgc tttttctctg tcgttcgcca agctctgcaa ccgcctcggg
    23821 cagcaggtag agactgccgt ttttttcaaa cagctgagaa aggggaaatt ctcttgaaac
    23881 ggcggataaa aaggccgccg cctcgcttcc ggccagctgt tccagagacg aggggatttt
    23941 tacggctttt cccgcgctgt catctgaacg gctgcctgca tcttctttcg gcgcttctgc
    24001 cgccgctttc ggatcctttt gaaggagagc aataaaatgc ccttccccct gaatccggtg
    24061 ggggaacagg cggacgcact gaggcagacc gatgccccgg gaaaagccct ccccctgggg
    24121 aagctccaaa agtttcatat caggaaaccg ctctaacaga taccggatcg tcccctcgtt
    24181 ctcttcctcg tcaaaggtgc aggtggaata caggagaagt cctccgggct tcagcatgtt
    24241 tacggcctca gagacaatag aacgctgaat ggggacgtag tctgacggcc cctgtttttc
    24301 gtagcttttg atcatatccg gatcccggcg gaacattcct tccccggagc agggggcgtc
    24361 caccaagatt ttatcgaaaa attccagaag caggccggac agcttttccg gcgtttcgct
    24421 ggacacgcag aaattggaga ttcccgccat ttccagattt tttaagaggg ccttggccct
    24481 ggaattgctg atgtcgttgg aaaacagcag cccttttccc tgaagcttcg cccccagctc
    24541 tgtgcttttg ccgcccggag ccgcgcagag atccagcacc cgatcccctg gaacaacagg
    24601 aaggagactg gccggagtca tggcgctggg ctcctgcaga tagtaaagtc ccgcgtaata
    24661 ccaggggtgc ttggacggcc ttatctctgc ctccgaagcc tcgtcgtcgg aagcgtaata
    24721 aaaaccgttc tcaatccagg gaacaggctt tatagagaag ggagcaatct gcttccaggt
    24781 ctccttatca atcttcagac ggttgatgcg cagaccgttg tggcagggct cttcaaaact
    24841 ttttacatac gcttcatact catctcccag aagcagtttc atcttttctt taaaatcagc
    24901 gggaagcgtt cccggctctc tgtttttttt cataaattct gttaccaacc atttctcttg
    24961 tatcgtgtta ataatcatac agaagcgtcc gcttttccag atatctgaga atccagtaag
    25021 gattaacgct cagctcctta aaatgctctg tctggatgta aatgcccagg tgcagatgaa
    25081 ccggaaaatt tcccacagtg ttctcctctc tgccgtatcc ggaatcgccc ataaagccca
    25141 gaagctctcc tgcttctacg gtgtctccct ctttccagtc tctgctgtag gagtaaagat
    25201 gggcatagta gagatatgct ccggaaggag agcggatgcc tatcctccag cctcccagct
    25261 ccagccatcc caccttttcc accgttccgc tgctcatgct gactacagga taaaagcctc
    25321 tctcccgctc tgttcccata atatcgcagc cctcatggcc ccgctctctg ccgtaggttc
    25381 tcttctgctg ccatccgtct tcatagaccg gccttggcgt atcgggacgg atgctggcgg
    25441 gaacaggaaa ataggccaga tccgagagta cggttctgta cccgtccgcc agcttttggt
    25501 acgctctggg ctttttcatc tcaagtattt tattatcata agacaaatct gtacattctg
    25561 tcaaatcgta attgtgctgg atcatcagag cggccagctg ttccggatcc agctggtcaa
    25621 gggcagagac agactctcca agcctcatgg cccggaaacc gtctgactcc agggcatagg
    25681 gcgtcaggcg ggccagcggg acagatgcga agagaaagcc tgtgacggct gtgataaaca
    25741 gggccagaag aaggagcaga attacaatca taacctcacc aattttttac atatagtgta
    25801 caaaacagtg tattcggtgg cttatgaaaa aatccttgtt tccgtctgcc atggcggcgg
    25861 ttatgggact tctgctcttc tgcccgtctc tggccctgaa gggggcaagg tccgggctgc
    25921 ttctgtggtt tcacaccgtg cttcccacgc ttcttccctt catgctgtgt tccagcgcga
    25981 ttgtggcctt tggagccgtg ccggccatta cctgccctct ggcccctctg ttttcccgtt
    26041 tatccctttc ggaaaacggc agctacgctc tgatggcagg cattctctgc ggctatccta
    26101 tggggccgaa aacggcggct gattttctgg cggaggagga aatttcgacg gaggaagcca
    26161 gataccttct ggcagtctcc gcctggccca gccccatgtt tctggccggt tatctggctg
    26221 tcctgctgcc tgcttccctc tccttcccaa aagtcctttt ctgcgtctat gcgccgatct
    26281 ttctgactgc agccctggca cgggcagttt accatgtacc gaaacaaaca tgcaaaaaac
    26341 agaaccagcg cccggcagtg aaaacttccg ttccggcttc cactggatcc ttcgatgaaa
    26401 ttttgatgga ctgtctggag attatggcaa aaatcggagg atatctcatg atcttctcca
    26461 ttctgtcctc attcgtgaca gccttttctc cgaaggaatg tttcctgcgc ccctatcttt
    26521 tgggactgat tgagatgacg accgggatcc gggaaatggc ctcctcctgc catccggatc
    26581 tgcttattgg agccggcatg acgggagccg ctgtgtttgg cggtctgtca ggtatcttcc
    26641 aggtttcagc ggtgataaag aaaaatgccg gactttccat ccggcattat gtactgtgga
    26701 agctgcttca cctgcttttg tccacggttc tgtttattct gctgtccctg tctgattagg
    26761 atccggagtc tcctccacca ggcttccggc taactcaatt cgattagagg aaacgatatc
    26821 atagctggac tggagggagg acgcaaagga atcaaagcgg ttctgagctt cgtccatcgt
    26881 atgctttaca atggtctgaa ggcttctcag catatcgtcg gtgtactgga cagagctctg
    26941 gcgcatggcg ttggcctcat tcacagcgcg gtctaagata gcctgtccct gcgtctgcgc
    27001 gttctgaata atgctctctg cctccgcata agccctctgc ataatctcat gctcgttgac
    27061 cagctcgttt gtctgctctg tggccttggc taccatggcg tctgcctgag agcgggcctc
    27121 ctgaaggatt gcgtcctgat tgctgataat cttctggtac ttcttaatct cctccggaat
    27181 acgaaggcgc agctccacca gaagctcctc gatctcttct ttatttacaa gaatctttgt
    27241 attggaaaga ggctgaaatt tacagctctc aatatattcc tcaatttcat tgataatctg
    27301 ctcaattctg ctcatagttc tctatctcct ttaccttttt atggctggcg gaacactttt
    27361 tctgcacctc tttcgccaca aggggatcca gaaacgccga aatgtcgccg ccgtacatgg
    27421 cgacttcctt cgaaatgctg gagcttaaat aggcgtattt taagttcgta gtcagaaaca
    27481 gtgtatcaat ctccggggca atgacgcggt tcatctgagc catctgaagc tcatattcaa
    27541 aatctgtaac ggcgcgtaag cctctgacga tgacctgggc ctccttcgcc cgtgcaaaat
    27601 cgatcagaag cccgtcaaaa gccatcacct ccacatttgg aagccctttt gttacgtctt
    27661 ttaacatctt aacacgttct tctacagaaa acaatggaga ttttgcacta ttattgagga
    27721 ctcctacaat cagtctgtca aaaatttttg aggaacgctc aataatatca tagtgtccca
    27781 gtgttactgg atcgaagctt cccggataaa tggctgtttt catagtactg ttttctcctt
    27841 tggtgtttaa gaattgcagt cagatagact gataaataaa tgcttgtttg tttcttcagt
    27901 acactctttg tcgctctctt ttttttcact tt
//
LOCUS       DBMDUW010000030        26634 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1283_length_26634_cov_3.650171, whole genome shotgun sequence.
ACCESSION   DBMDUW010000030 DBMDUW010000000
VERSION     DBMDUW010000030.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 26634)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 26634)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26634
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1283_length_26634_cov_3.650171"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            1..902
                     /locus_tag="ACZPCR_07175"
                     /pseudo
     CDS             1..902
                     /locus_tag="ACZPCR_07175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297587.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
     gene            1020..1634
                     /locus_tag="ACZPCR_07180"
     CDS             1020..1634
                     /locus_tag="ACZPCR_07180"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007869362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HIR1230695.1"
                     /translation="MIGSNIKNIVFDMGRVLLDYDPALVARHAGASEEETALIKKYLF
                     GSEEWILLDKGTITEEEAIRRIQDRLPNERLRKLAKECLDCWHEYNISPKPGMEKVVR
                     DLKAKGYRMYVCSNASLRFRVFQNEIPGFSLMEGALVSAEEKLLKPDPAIYRRLFEKF
                     DIRPEESFFIDDIQENIDGAKACGMDGYCFADGDVEKLREELGI"
     gene            complement(1677..2285)
                     /locus_tag="ACZPCR_07185"
     CDS             complement(1677..2285)
                     /locus_tag="ACZPCR_07185"
                     /inference="COORDINATES: protein motif:HMM:NF012235.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HIR1230696.1"
                     /translation="MAGSLRPREVCARHLSKSYQGRPVLSDVSLTVQPRERCALMAPS
                     GMGKTTLFRLLLGLETTDQGNIQTASAGAVFQENRLIESLSPIENVRLALPPLPKADT
                     RAELFSILSSLLPAESLTRPVSTLSGGMKRRCALARALLSPSEILILDEPFTGLDEDT
                     KKQAVQFIETWQKGRPLLFSTHDPKDVLLLQARLLPVDFKQS"
     gene            complement(2382..3134)
                     /locus_tag="ACZPCR_07190"
                     /pseudo
     CDS             complement(2382..3134)
                     /locus_tag="ACZPCR_07190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273999.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(3134..4219)
                     /locus_tag="ACZPCR_07195"
     CDS             complement(3134..4219)
                     /locus_tag="ACZPCR_07195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003509062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIR1230697.1"
                     /translation="MKKFKSAALAFALAASLIGCSAAPSETPETKEASEAQNASQTQE
                     ASQAQNASEAQKSPETQETPVRVGSLKGPTSIGLVHMMEEDAEAGNYQFTMAAAADEL
                     LASVVSEKLDIALIPANVASVLYQKTEGQVSVIDINTLGVLSMISGDSSIASWSDLAG
                     KTVYLTGKGTTPDYVLQYLLKEHASLDGFSPEDVTLEYKSEAAEIAAILKENPEAVGL
                     LPQPFATVAMSQNEALQTVFDLTEEWDKLQTESKSRLVTGVTIVRNGFLEEHPEEVEA
                     FLERHEESAKLALEEPDATASLIVKTGIIEKEPIAKKALPSCSIVFIEGNEMKDALSG
                     YLEVLFEQDPKSVGGSLPGDDFYYGAK"
     gene            complement(4270..5346)
                     /gene="ytvI"
                     /locus_tag="ACZPCR_07200"
     CDS             complement(4270..5346)
                     /gene="ytvI"
                     /locus_tag="ACZPCR_07200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HIR1230698.1"
                     /translation="MEMQKRRQFIINFLYFGIIFMLAFVLLKYGLPMVSPFAAGFVIA
                     CILRKPVLFLAEKLPLSQKAAAVLTVLLFYCTIGILFFLTGVKAFSAVRAFFFQLPEL
                     YTSHVEPVLNSIYRGFEESFLHMDPSLLASLEELVLQFSQSLGQLVSSLSGIAMGWVS
                     GAASSLPGLFISLLLLIISTFFIAADYETLTGFCLRQLSDRQREMFLLIKEYVVGTLL
                     VCIRSYALIMSITFIELSVGLTVIGVKNPIPIALLISIFDILPVLGTGGIMIPWIILE
                     ALTRNFTLSFALLAVYLFVTVVRNILEPKIVGTQIGLHPIVTLSSMFVGTQLFGVIGL
                     FGFPIGLSLLRYLNEKEMIHLFHN"
     gene            complement(5380..7017)
                     /locus_tag="ACZPCR_07205"
     CDS             complement(5380..7017)
                     /locus_tag="ACZPCR_07205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003022284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HIR1230699.1"
                     /translation="MNATDILGLLGGLALFLYGMQMMSAGLEDAAGNRMKQILERLTS
                     NRFLGVAVGAGITAVIQSSSATTVMVVGFVNSGMMTLKQAVWIIMGANIGTTITGQLI
                     ALDVGAIAPLFAFIGVVFIVFIKKVVFHHYGQIIAGLGILFIGMEMMSSSMMPLRDSA
                     AFVDLVSNFSNPLIGILAGMIFTAIIQSSSASVGILQALAVSGVIGLPTAVYVLFGQN
                     IGTCITAVLASIGTSRSAKRTTVIHLMFNIFGTVLFTVICMVTPLTSVMMSFAPDNPA
                     AQIANMHTLFNIVTTLLLLPFGTLLADLAERILPEQENEEPDVMRLCYIRPDDKSKEH
                     QIGSSAIVLTNIRSELSRMAKMAAENVESSFSAVIAQSPETLPQVEEKEEYIDFLNKE
                     IAKYISHTIAFEANERDSALISAFFKISGNLERIGDHAMNICEYTKRIEEKKIAFSDQ
                     AKEEIAQMKEVCSAAMKLLLPMEEMNVSALSEAAALEQKIDDLTLMFRQNQFKRMQKG
                     ICSDEACILYSEMLTDFERIGDHILNIGQELALSSPE"
     gene            7253..8875
                     /locus_tag="ACZPCR_07210"
     CDS             7253..8875
                     /locus_tag="ACZPCR_07210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative polysaccharide biosynthesis protein"
                     /protein_id="HIR1230700.1"
                     /translation="MERKQRHSGDNFLLQGSILAAAGILVRLIGLLYKIPMTRILGDE
                     GIGYYNTAYEIYNIGLILSSYSLPLAVSKLIAGKEQEGRRGDAKKVFHCGIFVGVVTG
                     GLMSLFLIVCSDRIAAEIFNSPGSALPLRVMAPTILVFAVMGVFRGFFQGRGNMVPTS
                     VSQVAEQLVHAGVSIWASWDFMNRFAGTENPSSYGAAGGTLGTLAGALAAFAILAVWM
                     AAARGNAGGLWRSEGGSREVSGYSEIMKLLLCTFAPIILSQFVYQLSGSVDNAMFGLI
                     MGGKGLDEAERLSLLGIYGGKYRLLTNVPVAIASSLGASMIPSIVASRVMKREQETAD
                     KIYMTIKFNMLLAIPCAAGMFALASPVMRLVFGDGRKLTAELLMLGSCAVVFFSLSTV
                     TNAVLQGIDQMRKSVTHSAISLAVHAVLVYVMLDKLNWGVYGLVIGNVTFALAVCVLN
                     WAAIGRTLGYRQEVKTTFLLPLFCSAVMGAAARLAYQGLMWATGSNTISLLAAAGLGA
                     VFYGWLLTTVGAVNEKELRSMPMGRLLLRFMR"
     gene            8971..10332
                     /locus_tag="ACZPCR_07215"
     CDS             8971..10332
                     /locus_tag="ACZPCR_07215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1230701.1"
                     /translation="MAGNEIKDMTKGSPFTLILGFALPMLIGLLFQQFYSMVDTIIVG
                     KYLGVKALAAVGSTGSLNFMIIGFCIGVCSGFAIPVAQRFGAGDYRGLRKYTANAAWL
                     SLVFSIVMAVIVCVLCRPILEWMKTPEDIIDQAFGYIFVIFAGIPATYLYNMTAGIIR
                     SLGDSKTPVYFLLLSSVLNIALDLFTIVVLKMGVAGAAYATVISQAVSGLLCLLYMKK
                     HFEILKMEKDEKKIDRHLIGRLCGMGIPMGLQYSITAIGSVILQASVNTLGSMAVAAV
                     AAGSKVTLFFCCPFDALGGTMATYAGQNVGAGKLDRIKAGLKSSSIIGCIYAVIAFLI
                     LVFFSDKIALLFMDAGETETIRQVSMFLIANSAFYIPLVFVNVVRFTIQGMGYSTFAI
                     LAGVFEMAARGLAGLVLVPAFGYIAACFGSPLAWIFADIFLFPAFFHCLKTMKRELKE
                     AKQ"
     gene            10570..11511
                     /locus_tag="ACZPCR_07220"
     CDS             10570..11511
                     /locus_tag="ACZPCR_07220"
                     /inference="COORDINATES: protein motif:HMM:NF012707.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HIR1230702.1"
                     /translation="MKMKQTALLTLTGLMAAVSLTACSGSAGGNSQTEAKTEAGSEAQ
                     STEAGSAAGSEAAESPEGEGRLAKIKEAGKITMATSPDFAPFEFKDISSGQVEYVGCD
                     IELAKYIADKIGVELEIQPMDFAAVQAAVTSGSVDMAIAGMSYTEERAENMGLSHGYD
                     YDRGDMPSTQGILVMADQVESYQTAEDFAGKKVAAQNGALQQGLVTEQLPDAQMETIT
                     TVNDGIMMLQTGKVDAVAVATSVGEPMIENYPELQFAGFWFETDDEGNVVGVPKGEDA
                     LLEVVNEAVEEVMEQGLYTQWHDEAVEKAKALGIEMD"
     gene            11561..12244
                     /locus_tag="ACZPCR_07225"
     CDS             11561..12244
                     /locus_tag="ACZPCR_07225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003500815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HIR1230703.1"
                     /translation="MLEKIINIWDKYWMLFMQGLGITLLLSLIIVIVGTLLGFLLAMF
                     RLSNWKIAKIRPLNTVAGIYVEIVRGTPMLLQLYFFYFMLPMAFPKMNLSPVVCATVA
                     LCLNSAAYVSEVIRSGIQAVDKGQMEAARSLGLNQKQAMVKVILPQAVKNIMPALGNE
                     FVMMIKDTSLASTFFVGELMTVWQTVRGVLYLSIEPLIIVGCIYFIVTFSLSKGIYYM
                     ERRMSANER"
     gene            12234..12974
                     /locus_tag="ACZPCR_07230"
     CDS             12234..12974
                     /locus_tag="ACZPCR_07230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008372631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HIR1230704.1"
                     /translation="MSGNNIITVENLHKRFGSLHVLKGVTEHIGKGEVVSIIGPSGGG
                     KSTFLRCLNLLEVPDEGQILFEGIDITDKKVDINLHRQKMGMVFQHFNVFPNMSVGKN
                     ITMSPVLLKKKTQKEADEMAKELLNRVGLLDKINEYPGKLSGGQKQRLAIVRALAMEP
                     EVMLFDEPTSALDPEMVGEVLDVIKGLVNTGMTTVIVTHEMGFAREVSDRVFFMDGGV
                     IAEKGTPSEIFEHPQNDRTKEFLGKVLY"
     gene            13041..14492
                     /locus_tag="ACZPCR_07235"
     CDS             13041..14492
                     /locus_tag="ACZPCR_07235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HIR1230705.1"
                     /translation="MGKKEALEYIDSKAELVTEVSDKIWGYAELSLMEHQSSELYVEV
                     LKKEGFQVETPVCGIETAYIASYGSGKPIIGILAEYDALSGLSQEAGAVERKEVIPGG
                     HGHGCGHNMLGAGAMAAALAVKHYLEEKGEGSGTVKFYGCPGEEGAASKAFMAKEGVF
                     NELDAALTWHPGTANEVTSGTCNSCIQTEYQFTGLASHAAGAPELGRSALDAVELMNI
                     GVQFLREHMSDECRIHYSITDTGGQSPNVVQPKAQVLYMVRAKLMKDAMKLQARVDKI
                     AEAAAMMTETTVKKKFIDGCSNTVPNKTLEQLLYRNFDQVGVPSYTEAELEFAKKLND
                     SCELAKEGLPGSMVDESFEAQEFVDQASCHGTKAMNDFLIPYIYSEKMRAGSTDVGDV
                     SWNTPTAQIRVACFTANAPGHSWQNVSCGATSIGHKGVLAAGKVLAGAAIDLMENTEL
                     LAEARAEFEKKTKGGYDCPIPDGAKPVLAGEQM"
     gene            14833..16035
                     /locus_tag="ACZPCR_07240"
     CDS             14833..16035
                     /locus_tag="ACZPCR_07240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase domain-containing protein"
                     /protein_id="HIR1230706.1"
                     /translation="MEERVALPVDKKRTGSFAAFRISFAVHGFRFPETPILFEDMGYG
                     FGRTGIAVLVLSAGQPRHWESGEMQAVCRGEQDIWKYCTKEQWKEMICSFGLLGDPEI
                     PQEIQMAVLYRFSRHSSCYYREKKIPKRFGGVRCLMIPDSGLKAVQRRILKHILSERP
                     VSSCACAYRKGVGIRDNAAAHVGQESVLKLDIEDFFGSITSSAVYGLAFPGTLFPPPV
                     RGLLTALCCCKGRLPQGSPASPAISNLVMKPFDDSMDLWCRQRGIRYSRYCDDMTFSG
                     SFEPGEVIRKVQSYLSELGMRLNRRKTGVYAKNCRQEVTGITVNQKAQLSKDYRRKLR
                     QECYYCRKYGIESHMERLGAGGQEAEEQVLARLLGKIEYLLSVDPANREFQAQREYFR
                     KLMKTLHT"
     gene            16061..16387
                     /locus_tag="ACZPCR_07245"
     CDS             16061..16387
                     /locus_tag="ACZPCR_07245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004078687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HIR1230707.1"
                     /translation="MEIVKKEQANGGEGAIFIKHILNETELNGKCKMFAEVTIPAGCS
                     LGYHVHHNESETYYIVKGEGEYNDNGTTRTVKAGERTFTPDGCGHGIANRTDQDLVFM
                     ALIILD"
     gene            16547..17716
                     /locus_tag="ACZPCR_07250"
     CDS             16547..17716
                     /locus_tag="ACZPCR_07250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0004529 - DNA exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HIR1230708.1"
                     /translation="MKFFHLSDLHIGRQLNGWSLKENQERVLAQITEYAGVYRPDAIL
                     ICGDVYDKSIPSGEAFSMFGHFLEQISETGIPALIIAGNHDSPERLGFAGPLLEKGRI
                     FLSSFPPSKEGEHLKKVTLKDRWGNVNFYLFPFMKPGYVRPLLRAEGREYEDTYDGAF
                     RAVLERETIDTSERNVILCHQFFTSSSGDPETCESETAVLTAGGLDAIGSSALDLFDY
                     AALGHIHGPQKAGRETVRYCGSPYKYSVSEERHKKSVVMAELTEKGEPAILTFLPLSG
                     IQDVRSVRGTLQEVLGKAEEPSCHDFVKITLTDDREPAYFREQLRERYDHILEIRIDN
                     ERTRESLKEEGEPMPVLSPMEVFRRFFTVVQKSEMTKEEEALMEQIIEEAKEEMK"
     gene            17713..20883
                     /locus_tag="ACZPCR_07255"
     CDS             17713..20883
                     /locus_tag="ACZPCR_07255"
                     /inference="COORDINATES: protein motif:HMM:NF024867.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HIR1230709.1"
                     /translation="MKPLKLTMSAFGSYVKETAIDFERLGDGIFLITGDTGAGKTTIF
                     DAIAFALYGETSGQRREGPMMRSQWAPPDQETRVELVFSDGGETYKIVRSPSYQRRSL
                     RKNKDGEYSMTLSQARASLTLPDGTEFPGRISDINEKIRSIVGIDREQFSQTAMIAQG
                     EYMRLLLASSKERKEIFSKIFDTGIYGAIQQKLREKNSALTRKLEDNRKFFEREASRL
                     QIPEDSCLGQRWKEVSGLLDSRGEEILKTVEEALAASLQAEKESRELEQQVLARKTGL
                     ERRLEAARAGEKLRQQQIRAEGLLQALEAERGLQEERKRRLKQAVEALPLQAKEEEIL
                     ANRSALAQSRKSAERLSGQLAALTERLAEADAQKKTAAEAFEREQPALLEQEARLREA
                     LPLYDSWEAAGRRLAQAEQAFRKTAETRKKTGEEKENSAAALALLKAEQEEKSRAPLL
                     LQKSREKRKRTEEKLDRIRSLKARLENLKERQTALSEEQRLLQQETSRYEEISREYDE
                     RNRRFICSQAGILALSLEEGVPCPVCGSRVHPAPASLAEAHVTEEELEKAKGQRDLAD
                     QRLRIHMEQVQTLRAQTEAESEQCKTLYLEMREASGEQVPVCLETALEEMKAFYDMAV
                     QDEQRQREEERQYQEEALRFEKLTDLIRREEEKFSALQERENRLREDEGALLAETASL
                     KTQWEEQKKRLPMEQKREAEERRIQIVGRLEQLSQRRQETEREAERLKQEEGTLKGQQ
                     EAEEKNGRRLEEQRTLLKSEFAERARRSGFANEGEYRKAICTEAERARLSEEISDYEA
                     QTAAARERANQCKEALKGASEESEDEVKPQLAELLEELSQARELSLKAAAARTEYEKA
                     YGAVKELLKERTALMEKYQLIHTLYITADGKMSQTARLDFQTFVQRQYFSQMIYAANR
                     RLKRMTEGRFILKCRDLEALSLQGEAGLDLDVYSVETDSVRNVKTLSGGEAFLAALAM
                     ALGMADVIQDTAGSVEMGALFIDEGFGSLDDEARARAIAVLKELSGGKRMIGIISHVA
                     ELREQIEKKITVKRGEEGSLVRVETE"
     gene            21393..22718
                     /gene="rsxC"
                     /locus_tag="ACZPCR_07260"
     CDS             21393..22718
                     /gene="rsxC"
                     /locus_tag="ACZPCR_07260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HIR1230710.1"
                     /translation="MGLATFIGGIHPFEGKELSEDKPIQVLPPLAGEEMVFPLSQHIG
                     APARPLVKKGDQVLKGQMIAEAGGFISANVICSVSGVVKGIEPRLAANGAMVDSIIVE
                     NDGEDRAVDGFGEHRDCTKLSKEEIRDIIKGAGIVGLGGAGFPTHVKLTPKDEAAIDH
                     VIVNGAECEPYLTSDYRLMMEQPEKIIGGLKVILQLFDNAKGVIGIENNKPEAIKKLT
                     EMVKDEPRIEVCPLLTKYPQGGERTLIYAVTKREINSSMLPADAGCVVDNIDTVVSIY
                     NAVCESTPLIRKIITVTGDAVANPQNYEVRLGTSYNRLIEAAGGFKTEPEKMISGGPM
                     MGQALFSTNFPVAKTSSALTCFTKDEVKAQAPTPCIRCGRCVDVCPEHLVPPLMMKAA
                     SAEDLDRFQSLNGMECVECGCCAFACPAKRPLTQAFKEMRKAVAASRRK"
     gene            22732..23670
                     /locus_tag="ACZPCR_07265"
     CDS             22732..23670
                     /locus_tag="ACZPCR_07265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HIR1230711.1"
                     /translation="MEKLLNVSSSPHVRNKITTQNLMFDVAIAMIPASVYGVWQFGMH
                     ALLVLIATVVSCVLSEYVYEKLMKKPITVSDGSAVVTGMILALNMPPEIPVWIPFLGG
                     IFAIIVVKQLYGGLGQNFMNPALAARCFLLISFAGFMNNFSSAKLGFDSMSGATPLAA
                     MRAGNDVDLMSLIVGRVPGTIGEVSVIALLIGAVYMIARKVISPRIPLIYIGTVAVFI
                     FLFGGFDITYVAKEVCAGGLIFGAFFMATDYVTSPLSKTGQVVYGLFLGILTGIFRLW
                     GASPEGVSYAIILGNLFVPLIEKVTLPKAFGKGAKK"
     gene            23670..24278
                     /locus_tag="ACZPCR_07270"
     CDS             23670..24278
                     /locus_tag="ACZPCR_07270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006775795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HIR1230712.1"
                     /translation="MKGILKDTFILFVITLVAGFCLGGVHDITLEPIAKAQQAAATAT
                     YKEVYPDAANFQETDELIEQASAAAADLEGQGFGKVSIDGAMEAVDANGAVIGYLITS
                     TSSESYGGDVQISVGITADGTITGVGFLAINDTPGLGMKAKEPAFKDQFNGRAAQTFE
                     VTKTAASGDAQIQAISGATITSSAVTNAVNAAVYFYTSCVAQ"
     gene            24290..24973
                     /locus_tag="ACZPCR_07275"
     CDS             24290..24973
                     /locus_tag="ACZPCR_07275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007157840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit E"
                     /protein_id="HIR1230713.1"
                     /translation="MNKYIERIYNGIWKENPIFVQMLGLCPTLAVTTSAINGIGMGLS
                     TTAVLVAANALIAALRNLIPDRVRLPAEIVVVASFVTIIDMLMEGFVPSLYSALGIYI
                     PLIVVNCIILGRAESYAMKNGVLLSIFDGIGMGLGFTVALGLIGAFRELLGSGMIFNI
                     QVAPASYQPVSIFILAPGAFFVLACLTALQNKLKAPCATNGSVKKEKKSGCCGDCASC
                     KDKDAKKDE"
     gene            24986..25561
                     /locus_tag="ACZPCR_07280"
     CDS             24986..25561
                     /locus_tag="ACZPCR_07280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002600142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex protein RnfA"
                     /protein_id="HIR1230714.1"
                     /translation="MKELLVIAISSALVSNVVLSQFLGICSFVGVSKKVETAAGMGGA
                     VIFVITIASIVSSLIYQFVLQPLGMDYLKTIVFILIIAALVQIVEMFLKKCMVSLYNA
                     LGVFLPLITTNCAVLGVALTNVQNGYGFVQSVVNGIGTAVGYTISIVLLAGIREHIEG
                     NDVPYSFQGSPIVLVTAGLMAIAFFGFSGLL"
     gene            25577..26368
                     /locus_tag="ACZPCR_07285"
     CDS             25577..26368
                     /locus_tag="ACZPCR_07285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HIR1230715.1"
                     /translation="MNVTAIIIAAVVIAATGIIVGIGLGLFGEKFKVEVDEKEAAVRE
                     ALPGNNCGGCGYPGCDGLAKAIAEGKAPANACPVGGAPVGEKIAAIMGVEAGSSEKMV
                     AFVKCKGTCDKTKVKYTYHGIEDCKKAAVVPGGGPKACTYGCMGFGSCVKACKFDAIH
                     VIDGIAVVDKEKCVACGKCVAACPQKLIDLVPYKAEHLVQCNSHDKGKDVKAKCDVGC
                     IGCTLCTKQCEFDAIHMDNNVAVIDYEKCTNCGKCAEKCPVKIIQ"
BASE COUNT         6906 a         5994 c         7733 g         6001 t
ORIGIN      
        1 tgggagaggt tactgtgtat gacagaactt cctatgagga ggatccgatt atcgcagaga
       61 gaattggcag cgcagagatt gtgattacga ataagacgcc tattacaaaa gaaaccattg
      121 acaaatgccc aaatctgaag ctgatcgctt ttctcgcgac tggatataac gccgctgatt
      181 acagctatgc ggcagaaaaa ggaatccctg ttgtaaacgt tcctacctac ggcactcaga
      241 ttgtcggcca gtatgccgtc ggccttctgt tagaaatctg ttcccactat ggccatcaca
      301 atcagacggt tcaggacgga acatgggaac gtcatcagga ctggtgttac tgggattatc
      361 ctatgattga attgtccgga aaaacggcgg gaattatcgg tctgggacgc atcggacaga
      421 caactgccag aattttaaag gcaatggata tgcgggtgct ggcatatgac gcccatccaa
      481 acgacgcagg cagggaaacg gcagaatatg tggatcttga taccttattt gccagctctg
      541 acgtcatctt cctgcactgc ccgctgtttc ctgagacaga ggggattatt aataaagaaa
      601 atatcggcaa gatgaaagac ggagttatta tcatcaacaa cagccgcgga cagttagtgg
      661 cagagcagga tttggccgac gcgctgaaga gcggaaaagt ccgcgcggca ggactggatg
      721 tagtctccac agaaccggtg aaaagcggta atcctctcct tcacctggat aactgaatca
      781 ttacccccca tatctcctgg gcagctaaag agtcaagaca gcggattatg gatattacag
      841 tagaaaatgt gaaggcgttc ctggagggaa atcccattca tgtcgtaaat atgggaaaat
      901 aagttctcgt aatataatgt gtttaaagct tatgaacata ataattcact tggctggctg
      961 ctttgtgcta taataactcc aaaaccagaa catagctgta ctgagtggag gaaggaaaaa
     1021 tgataggatc aaacataaaa aacattgtat ttgacatggg acgcgtgctg ttagactatg
     1081 atccggcgct tgtggccaga catgcggggg cttctgagga ggaaacggcc ctgattaaaa
     1141 aatacctgtt tggctcagag gaatggatcc tgctggacaa aggaaccatt acagaggagg
     1201 aggccatcag acgaatccag gacaggcttc ccaatgagag actgagaaag ctggcaaagg
     1261 aatgtctgga ctgctggcat gagtacaata tcagccccaa gccgggaatg gagaaggtag
     1321 tcagggactt aaaggcgaag ggatacagaa tgtacgtctg ctccaacgcc tccctccgct
     1381 tccgtgtatt tcagaatgag atcccaggct tttctcttat ggagggcgcg ctggtgtcgg
     1441 cggaagaaaa gcttttaaag ccggatccag ccatttacag acggctgttt gaaaagtttg
     1501 atatccgtcc cgaggagtcc ttttttatcg acgatatcca ggaaaatatc gacggagcga
     1561 aggcctgcgg aatggacgga tattgttttg cagatgggga tgtggaaaag cttcgagaag
     1621 agcttgggat ttaatacggt ctgagtgcag agaaagatgt ctctgcacgg cagacactag
     1681 gactgcttaa aatctacagg cagcagtctt gcctgaagaa gcaggacgtc ctttggatcg
     1741 tgggtggaaa agagaagagg tcttcctttc tgccaggttt cgataaactg gacggcctgc
     1801 ttttttgtgt cttcatccag accggtgaag ggctcgtcta aaatcagaat ctccgagggg
     1861 gagaggagcg cccgcgccag ggcacagcgg cgtttcattc ccccgctcag ggtggagaca
     1921 ggccgcgtca gggactccgc aggaagcagg gaggagagaa tagaaaacag ctctgcccgg
     1981 gtgtcagcct ttggaagagg cggcagggcc agacgcacat tttcaatggg cgaaaggctc
     2041 tctatcagcc ggttttcctg aaacacagct cctgcagaag ctgtctggat gtttccctga
     2101 tctgtagtct ccagccccag aagaagacgg aacagagtcg ttttgcccat cccggacgga
     2161 gccatcagag cgcagcgttc tcttggctgc acagtgagag aaacgtctga cagtacggga
     2221 cgtccctgat aggacttgga aaggtggcgg gcgcagactt cccgagggcg cagagatcca
     2281 gccatggcct tgattctgcc ggaagggatg gaggagggga cgcctgcgtt tttccgcact
     2341 gccgtcttta ctgacgcgga tgtgtgaagc ctctggcctg ctttctcaag cagaatgaga
     2401 aagccgcgct ccaggaacca ggacatggcg ataatgacgg cagtccaggc aaacagccgg
     2461 tccgtttcca ggtaaatttt agccgtgtag agctgttcgc cgatggaatg ctctggaatg
     2521 ccgatgactt ccgccgcgat tccggatttg atccccattc cgatggcaga acggcagttg
     2581 gctgccagat agggaagcag ggcaggcagg taaataaaac ggaatgttct tgtgaatgga
     2641 atctggaaaa cctgcgccat ttccagcagt ctgaaatcag cgctggccag tcctgccagt
     2701 accgactcat agatcatggg gaagactacc acaaaggaaa taaagaggga aaggcgtttc
     2761 gagccggccc aaatcagggc taaaatcaca aaggaaacga caggaacgga tttcatcagc
     2821 aggacggcag gagccagaag ctctctaaga ggccttaaaa aataggcggc agctccgaag
     2881 actgccgcca ggagaaaggc tcccagaaag cccaggctga tccgcaggca ggaggagaaa
     2941 aaaacactcc agaattctgc gagaaacagc tgggagacaa gcgcttttcc tgtctccaga
     3001 ggactggcca gaataatgga atttccaatg agcagggccg ccgcctgcca gagagccagc
     3061 cagaagagaa cggatgcaat tcggatgagg gaaggcgttg tctgccttcc cggttccagc
     3121 ttaacagact tcattatttt gctccgtaat agaaatcatc tccaggaagg gagccgccca
     3181 cagacttggg atcctgttca aataaaacct ctaaatatcc ggagagtgcg tctttcatct
     3241 catttccctc gataaatacg atgctgcagg agggcagagc ttttttggcg atgggctcct
     3301 tctcgataat tccagttttt acgatcagag aggctgtagc gtcaggttcc tctaaggcca
     3361 gcttcgctga ttcctcatgg cgctccagga aagcttccac ctcttctgga tgttcctcta
     3421 aaaagccgtt tctcacaatc gtaacgcctg tgaccagacg gctcttgctc tcagtctgaa
     3481 gcttatccca ctcctcagtc aggtcaaaca cagtctggag cgcttcgttc tggctcatag
     3541 ccacagtggc gaagggctgg ggcagaagtc ccacagcttc tgggttttct tttaatatgg
     3601 ctgcgatctc ggctgcctca gacttatatt ccagggtgac atcctccggg gagaagccgt
     3661 ccagggaagc atgctccttt aacaggtact gaagcacata gtctggagtc gttccctttc
     3721 ccgtcagata gacggttttt ccagccagat cggaccagga agcgatggag ctgtctccgg
     3781 aaatcatgga gagaacgccc agggtgttga tgtcgatgac agacacctgg ccttctgtct
     3841 tctggtagag aacgctggcc acattggcag gaatcagggc gatatccagc ttttctgata
     3901 cgacggacgc cagcagctcg tcggcggctg cggccatggt gaattggtag tttcccgctt
     3961 ctgcatcttc ttccatcata tgcaccaggc cgatggaggt gggccctttt aaggaaccga
     4021 ctctcacagg agtttcctgg gtttcagggg atttctgcgc ctcagaggcg ttctgtgcct
     4081 gtgaggcttc ctgtgtctgg gaagcgtttt gcgcctcaga ggcctctttt gtttccggcg
     4141 tttctgacgg agctgcagag cagccaatta aggaagccgc caaagcgaag gctaaggcgg
     4201 cggatttgaa ttttttcatg ataattacct cctttatccc tgtaagtata caggaaaatc
     4261 aggaaaatat caattgtgaa acaggtggat catctctttt tcgttgagat agcgcagtag
     4321 ggataagccg atggggaagc cgaacagtcc gatgactcca aacagctgcg tccccacaaa
     4381 catgctggat aaggtgacga tggggtgaag tccaatctgg gtgcccacga tcttcggctc
     4441 cagaatattt ctcactaccg ttacgaacag gtagacggcc aggagcgcga aggagagagt
     4501 aaaatttctg gtgagggctt ccagaataat ccatggtatc ataattccgc ctgttccgag
     4561 gacagggaga atatcgaaaa tggagattaa aagggcgatg ggaatggggt tctttacgcc
     4621 gatgactgtc agccccacag acagctctat aaaggtgatg ctcatgatca gggcatagga
     4681 gcggatgcat acgagaagcg ttcccactac atattccttg atcagcagga acatctctct
     4741 ctgcctgtca gagagctgtc tcagacaaaa tccggtcaga gtctcgtagt cggcggcaat
     4801 gaagaaggta gagatgatca gcagcagaag gctgataaaa agccccggca gggaagaagc
     4861 cgcgccggaa acccagccca tggcaattcc tgacaggctt gacaccagct gccccagaga
     4921 ctgggaaaac tgcagcacca gctcctccaa cgatgccaga agggagggat ccatatggag
     4981 aaaggattcc tcaaagcctc tgtaaatact gttcaggaca ggctccacgt gggaggtgta
     5041 gagttccgga agctggaaga aaaaggccct gactgcggaa aaggccttga cgcctgtcag
     5101 aaagaacaga atgccgatgg tacagtaaaa caatagcact gttaaaacag cggctgcttt
     5161 ctggctgaga ggaagcttct cagccagaaa cagcacgggt ttcctcagga tgcaggcaat
     5221 cacaaaacct gctgcgaagg gggagaccat aggcagcccg tatttcagca ggacaaaggc
     5281 cagcataaag atgatgccga agtataaaaa gttgatgata aactgtctgc gtttctgcat
     5341 ttccataaaa agccgtttta aacctttctg ttttccttcc tattccgggg aggaaagggc
     5401 cagctcctgg ccgatattta aaatgtgatc tccgatacgc tcaaagtcag tcagcatctc
     5461 tgagtagaga atgcaggcct cgtcggagca gattcccttc tgcatccgct taaactgatt
     5521 ctggcggaac atgagagtca gatcgtcgat tttctgttcc agggcagccg cctcagagag
     5581 agcggacacg ttcatctcct ccatggggag aaggagcttc atggctgcgg agcagacctc
     5641 cttcatctga gcgatttcct ccttggcctg atcggagaag gcgattttct tctcctcgat
     5701 ccgcttggtg tactcgcaga tattcatggc gtgatcgcca atccgctcca ggtttccgga
     5761 gatcttaaag aaggcgctga tcagagccga atcccgctcg tttgcctcaa aggcgatggt
     5821 gtgggagatg tacttggcga tttccttatt caggaagtcg atgtactcct ccttctcctc
     5881 cacctgcgga agcgtctcag gactctgggc tataacggct gaaaagctgc tctccacatt
     5941 ttccgccgcc atttttgcca tgcggctcag ctcgctgcgg atatttgtga ggacaatggc
     6001 ggaagaacca atctggtgct cctttgactt atcgtccgga cggatatagc acagacgcat
     6061 cacatccggc tcctcgtttt cctgctccgg gagaatccgc tcggctaaat ctgccagcag
     6121 agttccgaac ggcagcagaa gcagagtcgt cacgatattg aataaggtgt gcatgtttgc
     6181 aatctgagcc gccgggttgt caggagcaaa ggacatcatg acagaggtta acggcgttac
     6241 catgcagata accgtaaaca gaacggttcc gaatatattg aacatcagat gaatgacagt
     6301 ggttctcttg gcgcttctgc tggttccgat agaagccaga acagctgtga tgcaggttcc
     6361 gatattctgg ccgaagagca cataaacagc agtgggaagt ccgatcactc cgctgacagc
     6421 cagggcctga agaattccga cggatgcaga ggaagactgg ataatggcgg tgaaaatcat
     6481 tccggccaga attccgatta acgggttgct gaagttggat accagatcaa cgaaggcggc
     6541 ggaatcgcgc agcggcatca tggaggagct catcatctcc attccgataa agaggatacc
     6601 gagacctgcg ataatctgtc cgtagtggtg gaacactacc ttctttataa aaacaataaa
     6661 tacaacgccg ataaaggcaa agagcggggc gatggcgcct acgtcaaggg cgatcagctg
     6721 tccggtgatg gtagttccga tattggcgcc catgataatc cagaccgcct gctttaaggt
     6781 catcatgcct gagttgacga aacctacgac catgacggtg gtagcggaag aagactggat
     6841 cacagctgtg attccggctc cgacagccac tcccagaaaa cggttggatg tgaggcgttc
     6901 caggatctgc ttcatccggt tgcccgccgc gtcctccagt cccgcgctca tcatctgcat
     6961 tccgtagaga aagagcgcca ggcctccgag aaggccgagt atgtctgttg cattcataat
     7021 aaaattttcc tcctgaatat agttaagtag ggagcgcgcc ctttcggcgc gacacttccc
     7081 ggataatcat aaagaaaaag aaatgaaaag acaagcagaa tttacaaata tttacaaaga
     7141 tttaattgta caaatcttct ctaggaattt tttggaaaat gtagtaaaat attggctgcg
     7201 aaaaatgaca gaaatcgaac gctgagagac ggcatacaaa ggagaaagcc atatggaacg
     7261 aaaacagaga cattctggag ataattttct gctgcagggc agtattctgg ctgcggccgg
     7321 tattttagtg cggctgatcg gacttctcta taaaattccc atgaccagaa ttctggggga
     7381 cgagggaatc ggatattata acacggccta tgaaatctac aatatcggcc tgattctgtc
     7441 ctcctacagc ctgcctttgg cagtatcgaa gctgattgcc gggaaggagc aggagggcag
     7501 aaggggggac gcaaaaaagg tctttcactg cggaattttc gtgggagtgg tgacaggcgg
     7561 actgatgagc ctgtttctca tcgtctgttc cgaccggatt gcggcggaga ttttcaacag
     7621 tcctggaagc gcgcttcccc tcagggtgat ggcgccgacg atcctggtct ttgccgtgat
     7681 gggcgtgttc cgcggctttt tccagggcag gggaaatatg gtccccacct ccgtatccca
     7741 ggtggcggaa cagctggttc acgcaggagt cagcatctgg gcttcctggg actttatgaa
     7801 ccggtttgca ggaacggaaa accccagttc ctacggtgcg gcggggggaa ccctcggaac
     7861 gctggcagga gctttggccg cttttgcgat tctggctgtc tggatggcgg ctgccagagg
     7921 aaatgcagga gggctgtggc ggtcggaggg aggaagcagg gaagtgtctg gatattctga
     7981 gattatgaag cttctgctgt gtacctttgc gccgattatt ctgagccagt ttgtctacca
     8041 gctcagcgga tcggtggaca acgccatgtt tggcctgatt atgggaggca aggggcttga
     8101 cgaggctgaa aggctttccc ttctgggaat ttacggcgga aaatacaggc ttctcaccaa
     8161 tgttcccgta gcaatcgcct cctctctggg agcttccatg attcccagca ttgtggcttc
     8221 ccgggttatg aagagagagc aggagacagc ggataaaatt tatatgacga ttaaatttaa
     8281 catgctgctt gcgattccct gcgccgcagg aatgtttgcc ctggcctccc cggtgatgcg
     8341 cctggtgttc ggagacggga gaaagctgac ggcggagctt ctcatgctgg gatcctgcgc
     8401 ggtggttttc ttttccctgt ccacagtcac aaacgctgtg ctccagggaa ttgaccagat
     8461 gagaaagtcg gttactcatt cagccatatc cctggccgtc catgcggtcc tcgtctatgt
     8521 gatgttagat aagctcaact ggggcgtgta cggccttgta ataggaaacg tcaccttcgc
     8581 cctggctgtg tgcgtgttaa actgggctgc cattggacgg actctgggat acagacagga
     8641 ggtaaagact acgtttctgc ttcccctgtt ctgctctgcg gtgatggggg cggcggcgcg
     8701 ccttgcctac caggggctca tgtgggccac aggctccaac acgatttctc tcctggcagc
     8761 ggcaggcctg ggagctgttt tctacggctg gcttttaact actgtgggag cggtgaacga
     8821 gaaggagctg agaagcatgc ctatgggacg tcttctgctc cggtttatgc ggtagagacg
     8881 gctggttccg gcgcagagct tatgcagagc ggctgcggaa atggaacata catagatata
     8941 taagcacaga aagaaaggac ggagaagaga gtggcaggaa atgaaattaa ggatatgaca
     9001 aaaggatcgc catttacact gattctggga tttgccttac ccatgctcat cggactgtta
     9061 ttccagcagt tttacagcat ggtcgatacg attattgtag gaaaatacct gggagtgaag
     9121 gcgctggccg ccgtaggctc taccggttcc ctgaacttca tgattatcgg cttctgcatc
     9181 ggcgtatgca gcggttttgc catcccggtg gcccagaggt tcggggcggg agattaccgc
     9241 ggactgagaa aatacacggc caacgcggcc tggctgtctc tggtgttctc tattgtgatg
     9301 gctgtgattg tgtgcgtctt atgccgtccg attttagagt ggatgaagac gccggaggac
     9361 atcatcgatc aggcgttcgg ctatattttt gtgatttttg ccggcattcc ggctacctac
     9421 ctctacaaca tgacggcggg aattatccgc tctctgggag acagcaaaac gccggtttat
     9481 tttctccttc tgtcttctgt cttaaatatc gcgctggatt tattcacgat tgtcgtgctg
     9541 aaaatgggag tggcaggagc ggcctacgcc accgtcattt cccaggctgt atcgggactt
     9601 ctctgccttc tatatatgaa gaaacacttt gagattctga aaatggagaa ggatgaaaag
     9661 aaaattgacc ggcacctgat cggccggcta tgcggcatgg gaattcccat gggactgcag
     9721 tattcgatca cagccattgg aagcgtgatt ttacaggcct ccgtcaatac gctgggatcc
     9781 atggctgtgg cggctgtggc tgcaggcagc aaggtgactc tgttcttctg ctgtcccttc
     9841 gacgctctgg gaggcaccat ggccacctat gcgggccaga acgtgggagc ggggaagctt
     9901 gacagaatta aagcagggtt aaagagctct tccatcatcg gctgtatata cgcagtcatt
     9961 gcgtttctga ttctggtgtt tttcagcgat aagattgccc tgcttttcat ggatgcggga
    10021 gagacggaga ccatccgcca ggtttccatg ttcttgattg ccaacagcgc cttctacatt
    10081 ccattggtgt ttgtcaatgt ggtgcggttt accattcagg gaatgggcta cagcaccttc
    10141 gccattctgg cgggagtgtt cgagatggct gccagaggtc tggcgggcct tgtgctggtt
    10201 ccggctttcg gctacatcgc cgcctgcttt ggaagcccgt tagcgtggat ttttgccgat
    10261 atcttcctgt ttccggcatt tttccactgc ctgaagacca tgaaaagaga gcttaaagag
    10321 gcaaaacagt gaaatagaca gccggattag actgcgtcag tgcaggctga aaggaaagcg
    10381 cctggctgga aatcaaagga ccgtgttccg ttgatttcca gccttttgtc atatctgaat
    10441 gaataaaaat acatatttta tgaaaaaaac tattgacata ctgcatgaat agaggtatta
    10501 tacattacat gttaaatata tatacaaaaa aacgtataaa aataactgat atatgaggag
    10561 gatataatta tgaaaatgaa gcagacagca ttacttacac tgacaggttt aatggcagcc
    10621 gtttccctga ccgcatgttc cggttccgca ggcggaaaca gtcagacaga ggcgaagaca
    10681 gaggcaggaa gcgaggcaca gagcacagag gcaggaagcg cagcgggaag cgaggcggca
    10741 gagtcccccg agggagaggg acgcctggca aagattaagg aagccggaaa aattaccatg
    10801 gcgaccagcc cggacttcgc tccttttgaa tttaaggaca tcagctccgg acaggtagaa
    10861 tatgtgggct gcgatattga gctggccaag tacattgcag ataaaatcgg cgtagagctg
    10921 gagatccagc ccatggattt cgcggcggtt caggcggccg ttacatccgg ttccgtggat
    10981 atggctatcg caggcatgtc ctacacagag gagagagcgg aaaacatggg attatcccac
    11041 ggatatgatt acgacagagg cgatatgccg agcacccagg gaattctggt gatggccgac
    11101 caggtggagt cctaccagac agcggaggat ttcgcaggaa agaaggtagc ggctcagaac
    11161 ggagcgctgc agcagggact ggtgacagag cagcttccgg acgcccagat ggagacgatc
    11221 actactgtca acgacggcat tatgatgctt cagaccggca aggtagacgc agtggcagtg
    11281 gccacctccg taggagagcc gatgattgag aactatccgg agcttcagtt tgcaggcttc
    11341 tggtttgaaa cagacgacga gggcaacgta gtaggcgttc ccaaggggga ggacgctctg
    11401 ttagaggttg tcaacgaggc ggtagaggag gtcatggagc agggacttta cacacagtgg
    11461 cacgacgagg ctgtggagaa ggccaaggct ctgggaattg agatggatta atgaaaacca
    11521 gttgaaagag acggaatgaa aaagctgagg agagattgtt ttgttagaga agatcattaa
    11581 tatctgggat aaatactgga tgctttttat gcagggactt ggaattaccc ttcttttgag
    11641 cttaatcatc gtcatagtgg gaacccttct gggcttcctg ctggcgatgt tcagactcag
    11701 caattggaaa attgcaaaga tccggccgtt aaatacagtg gccggcatct acgtggagat
    11761 tgtcagagga acgcctatgc ttttgcagct gtatttcttt tactttatgc ttcctatggc
    11821 gtttccaaaa atgaatttaa gccctgtggt gtgcgcgacg gtagccctat gcctgaattc
    11881 ggcggcctat gtgtctgagg tcatccgttc cggaatccag gcggtcgaca aggggcagat
    11941 ggaggcggcg cggtctctgg gactgaacca gaagcaggcc atggtgaagg ttatccttcc
    12001 ccaggcagtg aagaatatta tgcctgccct gggaaatgag ttcgtcatga tgatcaagga
    12061 cacctcctta gcttccacct tctttgtagg cgagctgatg accgtatggc agacagtgag
    12121 aggcgtttta tacctctcca tcgagccgtt aattatcgtg ggatgcattt attttatcgt
    12181 taccttcagc ctgagcaagg gaatctatta catggagagg aggatgagcg caaatgagcg
    12241 gtaacaacat tattacagta gaaaatctgc acaagcggtt cggctccctc cacgtgctca
    12301 agggagtgac ggagcacatc ggaaagggag aggtggtttc catcatcggc ccgtcgggcg
    12361 gaggaaaatc caccttcctg cgatgcttaa atcttctgga ggttccggac gagggacaga
    12421 ttctctttga gggaatcgat attacagata aaaaagtaga tattaacctt caccgccaga
    12481 agatgggaat ggtattccag cactttaacg tatttcctaa catgagcgtg ggaaagaaca
    12541 ttaccatgtc tccggttctt ctgaaaaaga agactcagaa ggaggcggac gagatggcaa
    12601 aggagctttt aaaccgggtc ggcctgctgg ataaaatcaa cgaatatccg ggaaagctgt
    12661 caggcgggca gaagcagagg cttgccatcg taagggcgct ggccatggag ccggaggtaa
    12721 tgctctttga cgagcctaca agcgccctgg atccggagat ggtaggagag gttctggacg
    12781 taatcaaggg gcttgtcaat acgggaatga ccactgtgat tgtcacccac gagatgggct
    12841 ttgccaggga agtttccgac cgggtattct ttatggacgg aggcgtgatt gcagagaagg
    12901 gcacgccgtc tgaaattttt gagcatccgc agaacgacag gacgaaggag ttcttaggaa
    12961 aggtgctcta ttaaagagga tgcggcggac agccagaaca gatgagaatc cggcagagaa
    13021 cggatagtca ggaggaagag atgggaaaga aagaggctct tgaatatatt gacagcaagg
    13081 cagagctggt gacagaggtt tccgataaaa tctggggcta tgcagagctc tccctgatgg
    13141 aacaccagtc gtcggagctt tatgtagaag tgttaaaaaa agaaggcttt caggtagaga
    13201 cgccggtctg cggcattgag acggcttata tcgcttccta tggcagcgga aagccgatca
    13261 tcggcattct ggcggagtac gacgctttat ccggcctctc tcaggaggcg ggagctgtgg
    13321 agaggaagga agtgattccg ggaggacacg gccacggctg cggccacaac atgcttggcg
    13381 caggagccat ggctgcggct ctggctgtga aacactacct ggaggagaag ggagaaggaa
    13441 gcggaaccgt gaaattttac ggctgtcccg gcgaggaggg cgcggcctcc aaggcgttta
    13501 tggctaagga aggcgtgttt aatgaattag acgcagccct gacctggcat ccgggcacag
    13561 ccaacgaggt gacaagcgga acctgcaatt cctgtatcca gacagaatac cagtttacag
    13621 gccttgcttc ccatgcggct ggagctccgg agctgggacg ttccgccctg gatgcggtag
    13681 agctgatgaa catcggcgtt cagtttttaa gagagcacat gagcgacgag tgcagaatcc
    13741 actattctat tacagataca ggcggtcagt cccccaacgt ggtgcagcct aaggcgcagg
    13801 tgctctacat ggtacgggca aagctcatga aggatgccat gaagcttcag gccagagtcg
    13861 acaagattgc agaggcggct gccatgatga cggaaaccac tgtaaagaag aaatttattg
    13921 acggctgttc caatactgtg ccgaacaaga cgttagagca gctgctctac aggaatttcg
    13981 accaggtggg agttccttcc tatacagaag cggagctgga atttgcaaag aagttaaacg
    14041 attcctgcga gctggccaag gaggggctgc caggttccat ggtagacgag agctttgaag
    14101 cccaggagtt tgtagatcag gccagctgcc acggcacaaa agccatgaac gacttcctga
    14161 ttccctatat ttacagtgaa aagatgcggg caggttccac agacgtggga gacgtcagct
    14221 ggaatacgcc taccgctcag atcagggtgg cctgctttac ggccaatgcg cctggccaca
    14281 gctggcagaa cgtctcctgc ggagctacct ccatcggaca taagggagtg ctggcagcag
    14341 gaaaggtgct ggcgggagct gccatcgacc tgatggagaa tacagagctt cttgcagagg
    14401 ccagagcaga gttcgagaag aagacaaaag gcggatacga ctgcccgatt cctgacggcg
    14461 cgaagccggt tctggcagga gagcagatgt agggcttaca gatgaaataa aaagaaaccg
    14521 atacgtgttt tactctgcca tgctttcata aagcggcagg aggacgtatc ggttttttat
    14581 atgggataaa aagggaggag ccggcagtcg tctccaactg ccggcctgta tgaaaaagaa
    14641 tttataatta aaaaagtaac tgctttttta attgtcttta tcataccagg atagtgtgaa
    14701 aaaagtatgg aaaagatgtg aagaaattat gaacattttc gcggctttct tttttaaata
    14761 aattgtggta gcattagtgt acaggggaca tcaccggcag acggcagcga aaaagcgttt
    14821 catacaggct ttttggaaga gcgagtcgct cttcctgtgg ataaaaagag gacaggcagc
    14881 ttcgcagcct tccgaatctc cttcgccgta catggtttcc ggtttccgga aactcctatc
    14941 ctcttcgagg atatggggta cggctttgga agaaccggca ttgccgtttt agtgctgtct
    15001 gccgggcagc cgagacactg ggaaagcggg gagatgcagg cggtgtgcag aggagaacag
    15061 gatatatgga aatattgtac gaaggagcag tggaaggaga tgatctgttc ctttggactg
    15121 ctgggagatc cggagattcc ccaggagatc cagatggctg tgctctaccg ctttagcagg
    15181 cacagctcct gctattacag ggagaaaaag attccaaagc gttttggagg cgtccgctgc
    15241 ctgatgattc cagacagcgg gctgaaggcg gttcagagga gaattctgaa acatatttta
    15301 tcggaacgcc ccgtatcatc ctgcgcctgc gcttacagaa aaggcgtggg aatccgggac
    15361 aacgctgcgg ctcatgtggg gcaggagagc gttttgaagc tggatattga ggactttttt
    15421 ggaagcatca caagctcggc tgtctacggc ctggcctttc cgggaacgct gtttccgcct
    15481 ccggtgaggg ggcttctgac tgctctctgc tgctgtaagg ggagacttcc tcagggctct
    15541 cccgcatccc cggctatctc aaacctggtg atgaagccct ttgacgattc gatggatctc
    15601 tggtgcaggc agagaggaat caggtacagc aggtactgcg acgatatgac attctcaggc
    15661 tcgtttgagc caggcgaagt gatccgcaag gttcagtcct acttatcgga gcttggcatg
    15721 agattaaaca ggagaaaaac gggcgtatat gcgaaaaact gccgccagga ggtaactgga
    15781 atcacagtca atcaaaaggc ccagctctct aaggactaca gaagaaagct cagacaggaa
    15841 tgctattact gcagaaagta cggcatagaa agccacatgg agcggctggg agctggcggc
    15901 caggaggcgg aggagcaggt tctggcccgt ctgctgggaa aaatagagta tctgctgtct
    15961 gttgacccgg cgaacaggga atttcaggca cagcgggagt atttcaggaa gctgatgaaa
    16021 actcttcata cataaaaggc ggaataaagg aggaacaatc atggaaattg taaagaagga
    16081 gcaggcaaac ggcggcgagg gagctatttt tattaagcac attttaaatg agacggagtt
    16141 aaacggaaag tgcaagatgt ttgcagaggt gacgattccg gcaggctgtt ctctgggata
    16201 tcatgtgcac cacaatgaga gcgaaaccta ctacattgta aagggagagg gcgagtacaa
    16261 cgataacgga accacgagaa cggtgaaggc cggggagagg accttcacgc cggatggctg
    16321 cggccatggg atcgccaacc gcacagacca ggatctggta tttatggctc ttattatcct
    16381 ggactagaaa atcaggagac aaaccaggaa gcagaatagg aaatgcccgg catccagaag
    16441 agggaggcgc gccgctctgg accgggcatt ctcttattcc agcgtatgta agaagattct
    16501 gacagcgcag ggacgctgct ttttattttt tatcaggagg gactgaatga aattttttca
    16561 tctttcagat ctgcatatcg gaagacagtt aaacggctgg agcttaaagg aaaatcagga
    16621 gagggtcctc gctcagatta cagagtatgc aggcgtttac cggcctgacg ctattttaat
    16681 atgcggagac gtctacgaca aatccatccc gtccggggag gctttttcta tgttcggcca
    16741 ttttttggag cagatcagcg aaacggggat tccggctctt attattgcgg gcaatcatga
    16801 cagcccggag cggctgggat ttgcagggcc gcttctggaa aagggcagga tttttctgtc
    16861 gtcatttccg ccgtctaaag aaggagagca tctgaaaaag gttaccttaa aagacaggtg
    16921 gggcaatgtg aatttttacc tgtttccctt tatgaagcca ggctatgtga gaccgcttct
    16981 cagggcggag gggagagaat atgaggatac ctatgacggc gcgttccggg ctgtgctgga
    17041 gagggaaacg attgatacgt cagagcggaa tgtaatcctc tgccaccagt tttttacaag
    17101 cagttccggg gatccggaaa cctgcgaatc ggagacggcg gttctcacgg caggagggct
    17161 ggacgccata ggaagttctg ctctggatct gttcgactac gcggctctgg ggcatattca
    17221 tgggcctcag aaggctggca gggagacagt cagatactgc ggctctcctt ataagtattc
    17281 ggtcagcgag gagcgccata aaaagtcagt ggtgatggcg gagcttaccg aaaaaggaga
    17341 accggcgatc ctgacttttc tgcctctgtc cgggattcag gacgtcagaa gcgtcagggg
    17401 aacgcttcag gaggtgttag gaaaggcgga ggaaccgtcc tgccacgatt ttgttaaaat
    17461 tacgctgaca gacgacagag agccggcgta tttccgcgaa cagcttcggg agagatatga
    17521 tcatattctg gaaatcagga ttgacaatga gaggacaaga gagagcctga aggaggaggg
    17581 ggagcctatg ccggtattaa gccccatgga ggtgttccgg cggtttttta ctgtggtgca
    17641 gaaaagtgaa atgacgaagg aggaggaagc tcttatggag cagatcatag aggaagcaaa
    17701 ggaggagatg aaatgaagcc gctgaagctt accatgtctg cctttggctc ttatgtgaag
    17761 gagacggcga tagattttga gaggctgggg gacggcattt ttctgattac aggcgatact
    17821 ggagcgggaa aaaccacgat ttttgacgcg attgcatttg ccctctatgg cgagaccagc
    17881 gggcagagaa gagaggggcc catgatgcgc agccagtggg cgccgccgga tcaggagacg
    17941 agggtagagc tggttttttc tgacggggga gagacctaca aaattgtcag gagtccttcc
    18001 taccagagaa ggagccttcg gaaaaataag gacggagagt acagcatgac tctgtcgcag
    18061 gccagggctt ccctgacgct tccggacgga acggaatttc ctgggaggat ttccgatatc
    18121 aatgaaaaaa tccgctccat tgtggggatt gacagggaac agttttccca gactgccatg
    18181 attgcccagg gagagtatat gaggttgctg ctggccagct caaaagagcg gaaggaaatt
    18241 ttttccaaaa tttttgacac tggaatttat ggggcgatcc agcagaagct gcgggagaaa
    18301 aacagcgccc tcaccaggaa gctggaggac aaccggaaat tttttgagag agaagcctcc
    18361 agactgcaga ttccggagga cagctgtctg ggacagagat ggaaggaggt ttccgggctg
    18421 ttggattcca ggggggaaga aattttaaag acagtggaag aggcccttgc ggccagtctt
    18481 caggcggaga aggaaagccg ggagctggaa cagcaggttc tggccagaaa gaccggtctg
    18541 gagcggagac tggaggccgc cagggcaggg gaaaagcttc ggcagcagca gatccgggca
    18601 gagggactgc ttcaggctct ggaggcagag cgcgggcttc aggaagagcg gaaaaggcgg
    18661 ctgaaacagg cagtagaggc tctgcctctt caggctaagg aggaggagat ccttgccaac
    18721 agaagcgcat tggcacagtc cagaaagagc gcggagcgtc tgtctggcca gcttgcagcc
    18781 ctcacagaaa gactggcaga ggctgacgcg cagaagaaga cggcggccga agcctttgag
    18841 agggaacagc cagccctttt ggagcaggag gcaaggctga gagaggcgct tcccctctat
    18901 gacagctggg aagcagcggg acgccgcctg gctcaggcgg agcaggcctt cagaaagacg
    18961 gcagaaacgc ggaaaaaaac aggggaagaa aaggaaaact ccgcagcagc gctggccctc
    19021 ctgaaagcag agcaggagga aaagagccgc gcgccgcttc ttctccagaa aagcagagaa
    19081 aagcggaaac gcacagagga aaagctggat cggatcagaa gcctgaaagc gcgtctggag
    19141 aacctgaaag agagacagac cgcgctttca gaggaacagc gtctgctgca gcaggagacc
    19201 agccgctacg aagagatttc cagagaatat gatgaacgaa accgcagatt catctgctcc
    19261 caggccggaa ttctggctct gagcctggag gagggggttc cctgtcctgt ctgtggttcc
    19321 cgggttcacc cggctcccgc ctcgctggca gaggcacatg tgacagagga ggagctggaa
    19381 aaggcaaagg gacagaggga tctggccgac caaaggctgc ggattcatat ggagcaggtt
    19441 cagactcttc gggcgcagac agaagcagaa tcagagcagt gcaaaacgct ttatctggaa
    19501 atgcgggaag cttccgggga gcaggttccg gtctgtctgg aaacggcgct ggaagaaatg
    19561 aaagccttct atgatatggc tgtacaggat gaacagagac agcgggagga ggaaagacag
    19621 taccaggaag aggccctccg gtttgagaaa cttacagatc tgatccgcag agaggaagaa
    19681 aaattcagcg ctctgcagga gcgggagaac cggctgagag aggatgaggg ggcgcttttg
    19741 gctgagacgg caagccttaa aacacagtgg gaggaacaga aaaaacgcct tcccatggaa
    19801 cagaagagag aggcagaaga gaggcggatt cagattgtcg gccgcctgga acagctgtca
    19861 cagcgcagac aggaaacaga aagggaagca gaacggctga aacaggagga aggaacgctg
    19921 aaagggcagc aggaggcaga agaaaagaat ggcagaagac tggaggaaca gaggacgctg
    19981 ttaaaatcag agtttgctga aagggccaga agatccgggt ttgccaatga aggggagtac
    20041 agaaaggcga tctgcacgga agcggagaga gcgcggcttt cagaagaaat ttctgactat
    20101 gaggcgcaga cagccgctgc cagagaacgg gcaaaccagt gtaaagaagc gctgaaagga
    20161 gcgtcagagg aatcagagga tgaagtaaag ccgcagcttg cagagctttt ggaagaattg
    20221 tcacaggcca gagagctttc cttaaaggca gcggcggcca ggacggaata tgagaaggcg
    20281 tatggggccg taaaggagct tttaaaggag aggacggctc tgatggagaa gtatcaactg
    20341 atccacaccc tctatataac ggcggatgga aaaatgagcc agacggcccg gctggatttt
    20401 cagacctttg tgcagcgcca gtatttttcc cagatgattt atgctgccaa ccggaggctg
    20461 aagcggatga cagaagggcg gtttatttta aaatgcagag atctggaagc cttgagcctt
    20521 cagggagaag cgggacttga cctggatgtg tacagcgtgg agacggacag cgtcagaaat
    20581 gtgaaaacat tatcaggagg ggaggcgttt ttggccgctc ttgccatggc gcttggcatg
    20641 gcggacgtaa tccaagatac ggcgggaagc gtggaaatgg gcgcgctttt tatcgacgag
    20701 ggctttggtt ctctggacga cgaggcgaga gcgagagcta tcgccgtgtt aaaggagttg
    20761 tcgggaggaa agcggatgat aggaatcatt tcccatgtgg cggagctgag agagcagatt
    20821 gaaaagaaga ttacggtaaa gcgcggcgag gagggaagcc tggtaagggt ggagacggaa
    20881 taaacgcgcc aagagaacag gcgagaaccg taggaagttt tcacgctcca ccaaaagctt
    20941 agccgctgga aaacttctgc ggttcttgaa tgttttactc tgttctgccc tgatccaggc
    21001 ctttcgccct gaatcagact tttgccatga tccaggtctt tcgccctgaa tcagaccttc
    21061 gtcatgatcc aggcctttca agccgcagac cggccatgtt tcagtttgca acatggccgg
    21121 tctgcggctt gggggcttcg ccccatactc ccgtaagaat caggctctgc tgggaagtga
    21181 acttcccgac agagcctgat tcttacggga gtgcctggct cagtgtacac aaaaatgtac
    21241 acaacttcca gctttgaact taaatttttt aattgtgaaa tttttctcac tatggtatac
    21301 tttaaaagat aaagcttttc agtacaatgt gacaaaagat gttacgattt cataaagaaa
    21361 agcaaaacaa actagagaaa gagggttatt aaatgggttt ggctacattt ataggcggca
    21421 ttcatccttt tgaaggcaaa gagctgtctg aggacaagcc gattcaggtt ctgcctccgt
    21481 tagcgggcga agagatggtt ttcccgctgt cccagcacat cggcgctcca gcgcgtccgc
    21541 tggtgaaaaa gggcgaccag gtgctgaagg gccagatgat tgcagaggcc ggcggtttta
    21601 tttctgccaa tgtaatctgc tctgtttccg gcgtagtgaa gggaattgag cccaggctgg
    21661 ctgccaatgg cgctatggtt gactctatta tcgtagaaaa tgacggagag gaccgcgcag
    21721 tggacggctt tggggagcac agagactgta ctaagctctc caaggaagaa atcagggaca
    21781 tcattaaagg agcaggcatt gtaggtctgg gcggcgcagg cttcccgacc catgtaaagc
    21841 tgactccgaa ggacgaggct gccattgacc atgtcattgt caacggcgca gagtgtgagc
    21901 cgtatctgac cagcgactac agactgatga tggagcagcc ggaaaagatc atcggcggtc
    21961 tgaaagtgat tttacagctg tttgataatg ccaagggcgt gatcggcatt gagaacaaca
    22021 agccggaagc tatcaagaag ctgactgaga tggtgaagga cgagccgcgc atcgaggtat
    22081 gtccgcttct caccaaatac ccgcagggcg gcgagcgtac tctgatttac gcagtgacaa
    22141 agagagagat caactcctcc atgcttccag cagatgcagg ctgtgttgtg gacaatattg
    22201 atacggttgt ttctatttat aatgctgtat gcgagtccac tccgcttatc agaaagatca
    22261 ttacagtgac aggagacgca gttgccaatc cacagaacta tgaggtgaga ctgggaacca
    22321 gctacaaccg tctgattgag gcggcaggcg gatttaagac tgagccggag aagatgattt
    22381 ccggaggtcc tatgatggga caggcgttat tcagcacgaa cttcccggtt gccaagactt
    22441 cctccgctct tacctgcttt acaaaggacg aggtaaaggc ccaggctccg acgccgtgta
    22501 tccgctgcgg acgctgcgtg gatgtatgtc cggagcatct ggttccgccg ctgatgatga
    22561 aggcagcttc cgctgaagat ctggatcgct ttcagagctt aaacggcatg gagtgcgtag
    22621 agtgcggctg ctgtgccttt gcatgtccgg ccaagagacc tctgacacag gcgtttaagg
    22681 aaatgaggaa ggcagttgcg gccagccgca gaaagtagga ggtgtgaaga aatggaaaaa
    22741 ttgttaaacg tatcgtcatc acctcatgtg cggaataaga ttaccactca gaatctgatg
    22801 tttgatgtgg cgattgctat gattcccgcc agcgtttatg gtgtatggca gtttggtatg
    22861 cacgcgcttc tggtgctgat tgctaccgtg gtttcctgcg tgctgtccga gtatgtatat
    22921 gagaaactga tgaagaagcc gattacggta agcgacggca gcgccgtggt gacaggtatg
    22981 atcctggctc tcaacatgcc gccggagatc ccggtgtgga tcccattcct gggcggtatc
    23041 ttcgctatta tcgtagtaaa gcagctgtac ggcggactgg gacagaactt tatgaacccg
    23101 gctctggcag ccagatgctt ccttttaatt tcctttgcag gatttatgaa caacttctct
    23161 tccgcaaagc ttggctttga cagtatgtcc ggagcgacgc ctctggcagc tatgagagcc
    23221 ggaaatgacg tggatctgat gtccttgatc gtgggacgcg ttcctggaac catcggtgag
    23281 gtttccgtca ttgcgctgtt aatcggagct gtttatatga tcgcaaggaa ggtcatcagc
    23341 ccaaggattc ctctgattta cataggaacc gtagctgtgt ttatcttcct gttcggcggc
    23401 tttgatatta cctacgtggc aaaagaagta tgcgccggcg gtcttatctt cggagccttc
    23461 ttcatggcga cagactacgt taccagcccg ttaagcaaga ctggacaggt tgtgtacggc
    23521 ctgttcttag gtattctgac tggtattttc cgtctgtggg gagcttctcc tgagggtgta
    23581 tcctacgcaa ttatcttagg aaaccttttc gtgccgctga ttgagaaagt gacacttcca
    23641 aaggcattcg gaaagggggc taaaaaataa tgaagggaat tttaaaagat acatttatcc
    23701 tgtttgttat tacccttgta gcaggcttct gtctgggagg cgttcacgat attaccttag
    23761 agccgattgc caaggctcag caggcggctg ccacagctac ctataaagag gtgtatcccg
    23821 acgcggccaa tttccaggag acagatgagc tgatagagca ggcgtctgcc gcagctgcag
    23881 atctggaagg ccagggcttt ggaaaagtaa gcattgacgg cgccatggag gcggttgacg
    23941 caaacggcgc agtgattggc tacctgatca cttccacatc ctccgagagt tacggcggag
    24001 acgtacagat ttccgtggga atcacagctg acggaaccat tacaggagta ggctttttag
    24061 ctatcaacga tactccggga cttggtatga aagccaagga gcctgccttt aaagaccagt
    24121 ttaacggcag agcagcccag acatttgagg tgacaaagac ggcagcttcc ggagatgccc
    24181 agattcaggc tatcagcggc gctaccatca cttcttccgc agtgacaaac gcagtaaatg
    24241 cagccgtata cttctatacc agctgcgttg cacagtagga ggtggagaca tgaataagta
    24301 tatagaacgt atttataatg gtatctggaa ggaaaacccg attttcgttc agatgctggg
    24361 actgtgtcct acactggctg ttaccacttc agcaattaac ggaattggaa tgggactttc
    24421 cacaacagcg gttctcgtgg cggccaacgc ccttatcgct gccctcagaa acctgattcc
    24481 tgacagagtc cgccttccag ctgagattgt agtagtagct tctttcgtaa cgattatcga
    24541 catgctgatg gagggcttcg tgccttctct gtacagcgct ctgggaatct acattcctct
    24601 gatcgttgta aactgtatta tccttggacg tgcagagtcc tacgccatga agaacggcgt
    24661 gctgctttcc attttcgacg gtatcggaat gggacttggt ttcacggtag cccttggatt
    24721 aatcggagcg ttccgtgagc ttctcggatc cggtatgatc tttaatatcc aggtagctcc
    24781 ggcttcctat cagccagtat ctatctttat tctggctccc ggcgctttct ttgtacttgc
    24841 ctgcctgaca gcgcttcaga ataagctgaa agctccgtgc gctacaaacg gctccgtgaa
    24901 gaaggagaaa aagtccggat gctgcggcga ctgcgcaagc tgcaaggata aagatgcaaa
    24961 aaaggatgaa taggaggaag catagatgaa agagttactt gttatagcga taagctcagc
    25021 tcttgtgagc aatgtcgtat taagccagtt ccttggtatc tgttccttcg tcggcgtatc
    25081 gaaaaaggtg gagacggctg ccggtatggg cggagcggtt atcttcgtta ttaccatcgc
    25141 ctccattgtt tccagcctga tttatcagtt tgtgctgcag ccgcttggaa tggattacct
    25201 gaaaacaatc gtatttatcc ttatcatcgc tgctctggtt cagattgtag agatgttctt
    25261 aaagaagtgt atggtatccc tgtacaacgc cctgggcgtg ttcctgccgc tgatcactac
    25321 aaactgcgcc gtactgggcg tagctttaac caacgtgcag aacggctacg gctttgtgca
    25381 gagcgttgta aacggtatcg gtacggcagt gggctacacg atctccatcg tgctcttagc
    25441 cggaatccgc gagcatattg agggcaacga cgttccctac agcttccagg gttctccgat
    25501 cgtacttgta acagcaggat taatggcgat tgcatttttc ggattttccg gattactgta
    25561 gagggaggat acgaaaatga atgttacagc aattattata gcagccgttg taatcgcagc
    25621 taccggtatc atcgtaggta tcggtctggg actcttcggt gaaaagttta aggttgaggt
    25681 agacgaaaaa gaggctgctg tccgcgaggc ccttccaggc aacaactgtg gcggctgcgg
    25741 ataccctggc tgcgacggtc tggcaaaggc catcgcagag ggaaaggctc ctgccaacgc
    25801 ctgtccggta ggcggcgctc cggtaggaga gaagatcgcg gctatcatgg gcgtggaagc
    25861 cggaagcagc gagaagatgg tagctttcgt aaagtgtaag ggaacctgcg ataagacaaa
    25921 ggtgaaatac acctaccacg gaatcgagga ctgcaagaag gcagccgttg ttccgggagg
    25981 cggaccgaaa gcctgcacct atggctgcat gggatttggc tcctgtgtga aggcctgcaa
    26041 gttcgacgcc atccatgtca tagacggaat tgccgtagta gacaaggaaa agtgcgtagc
    26101 ctgcggcaaa tgtgtggcag cctgcccaca gaagctgatc gacctggttc cgtacaaggc
    26161 ggagcatctg gttcagtgca actcccatga taaaggcaag gatgtaaagg ccaaatgtga
    26221 cgtggggtgt atcggctgta ctctctgcac taagcagtgt gagtttgatg ccattcacat
    26281 ggacaataat gtagctgtta tcgattatga gaagtgtacg aactgcggca agtgcgcaga
    26341 gaagtgcccg gtaaaaatta ttcagtagag aaaaaggacg ttccgagtgg gcaatgtcat
    26401 taagttgaaa cattgaattg aacggttctt tgtaacagag atggtagaat tgaattctgc
    26461 tatctctgtt tttctatttc aaagcacagc aattagacag attttcatct gtctaaaaaa
    26521 taagtattca attaggcagt tttatgatac tctgtataag aaaccatgaa atatttttgc
    26581 agttagattg cgttctctgt gtttatctgg tcttattggc acaagatttc ttgc
//
LOCUS       DBMDUW010000031        26591 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1285_length_26591_cov_3.402945, whole genome shotgun sequence.
ACCESSION   DBMDUW010000031 DBMDUW010000000
VERSION     DBMDUW010000031.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 26591)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 26591)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26591
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1285_length_26591_cov_3.402945"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            403..1764
                     /locus_tag="ACZPCR_07290"
     CDS             403..1764
                     /locus_tag="ACZPCR_07290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1230716.1"
                     /translation="MKMENDLGRDDIRLLVMRIALPSMLAQFVSVLYSVVDRMYIGNI
                     PEIGETALAGVGVCGPIVTLITAFGSLVGIGGAPLMSIRLGEKDEKGASQILANCFLL
                     LSVISVVITALSLLMKNKLLVWFGASTSIFPYADDYITIYLLGTIFALLSIGMNQFII
                     CQGFAKVAMKSVVLGAVVNIALDPVFIFACGMGVRGGALATVLSQMASAGYVLLFLFG
                     KKVPVPITFGGYQWRIMKRVILLGLSPFLIIAFDNVLIIAMNASLQHFGGAEGDMLLT
                     CNTIVQSFMLMVTMPLGGITGGTQTILGYNFGARRSDRVLAAQQYIVILSMAFTAVMF
                     VIAQTVPHYFVQIFTRDPEYVELTVRAIRIFTLGIIPLAVQYEIVDGYTGMGIAPIAI
                     SLSTVRKTLYLLGVVLIPMFFSVEAVFYTEPISDFLGTAVSITVYLMTMKKILRRREN
                     GEM"
     gene            complement(1842..2870)
                     /locus_tag="ACZPCR_07295"
     CDS             complement(1842..2870)
                     /locus_tag="ACZPCR_07295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005488 - binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TAXI family TRAP transporter solute-binding
                     subunit"
                     /protein_id="HIR1230717.1"
                     /translation="MNHPRHPRFISARTAIGIFTAALLLCSCSLTGRSASLSSSTEPS
                     AGAITVLTIGTADSGGSMYPAGEAIAEAIETTSHHIHVNICASNGSYTNIQMLSDGQI
                     DLGLVSGDAAYAAFHGTHEFSTDPQTGLRTIGAVYSSISNWMALNSSSLFYVHDLKGK
                     RVSVGPEASNTDLSARIVFDLFDITRENTEIETRGGIGYGAEEVLKGTLDAVHGFAGT
                     PIEGLYNLSVQTPSRLLKYTASELNQILSENNFYYPTRIPAGTYEGQAEDIDSFGVKC
                     LICVDDSLDEELVYKLTSILYSRREPLGKKQVLLKPMSEDGFMYSELPIPLHPGAERF
                     YQEQGLLP"
     gene            complement(3158..4408)
                     /locus_tag="ACZPCR_07300"
     CDS             complement(3158..4408)
                     /locus_tag="ACZPCR_07300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009532467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015501 - glutamate:sodium symporter
                     activity [Evidence IEA];
                     GO_process: GO:0015813 - L-glutamate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HIR1230718.1"
                     /translation="MEAILSYFGTYTPAADGAVASFKFEYLTTLGFAAIVIFAGRAIV
                     AHSALLRKYAIPAPVVSGVIFSIIVSVIKGAGIIGISFDTKIMQDLCQNLFFLCVGFG
                     FSLKMIKHAGGKLCIMIAVAACLLITLQDIVGVLVGNAIGLHPLLALQCSSASMSGGV
                     GTASAFGAIFEEWGAPNATTIGVAAGTCGNIMGSLIGGPVAAFLITHHKLKADPNDKP
                     ESAKTGEVIPLTNSRMISMFAMCLLVAALGMPIYCILDNIPMIEMPKFIGCLFAGAIA
                     RNVMEAMNIKFYTPEVDAIEHMFLELYLALVLMTIDITALAPVAGQMGIILLVQAVLI
                     ALFAIFISYNMFGRNYGAAVMAAGNCGWGCGSGPNAVANEKAVMDAYGWHNVAWVLYP
                     SFAVIIDDIYNPIFLSVFGGIIGK"
     gene            complement(4525..5214)
                     /locus_tag="ACZPCR_07305"
     CDS             complement(4525..5214)
                     /locus_tag="ACZPCR_07305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008398960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HIR1230719.1"
                     /translation="MYSVIIVEDDPMVASINRQYVELEPSFSVKQSFKSGQDALSWLS
                     REEADLIILDYYMPLMTGKEFIDRLHSMGKAPSVIMVTSASDSAIVQELLSRGVLDYL
                     VKPFERSRFRQALSRFAQTRSCLDGSPELNQAEIDRLLSHMQPSSSFQTELAKGLSET
                     TLNLIRNFLQNRPGEFFSSEQIAEQVFLSRITIRRYVNYMLEMGEIISSVDYQTGGRP
                     SIKYTCSCHVL"
     gene            complement(5202..6101)
                     /locus_tag="ACZPCR_07310"
     CDS             complement(5202..6101)
                     /locus_tag="ACZPCR_07310"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: protein motif:HMM:NF014567.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1230720.1"
                     /translation="MPDSLEEKQLSALFPDTDCSSLLSRDALRNRADTSHFSVSSLIT
                     NVGSRTLLIKAIPIIKKDSVKGVLMVLNDRTEMLRMSDELSGTRATLDTLRAFNHEFM
                     NKLHVILGYLQTGETKKAITFIMNSSLVSSQAVRETAERIRVSSICALIIGKMMHAAE
                     LGIRLSLSPDSICLEHDLLIPSEEMITAVGNLLENAVEELADPANAHRAIKEIKLSLF
                     CRRDFNLIVCEDTGRGICRELAGRICDKGISTKGDNRGLGLFLIKEIAARRGGELTIE
                     TEEGEGTIITLAFTRKENETCIQ"
     gene            complement(6094..6939)
                     /locus_tag="ACZPCR_07315"
     CDS             complement(6094..6939)
                     /locus_tag="ACZPCR_07315"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230721.1"
                     /translation="MKQVNFRILNLYRMKNSAGKTHGNTCKKQKKSTLETTLSRSFFA
                     VSAVLLLLSLGITMYYDITRQRKEVDSTISGLAAYIASMPQVIDMLQMGYPSDSVRKD
                     LDSLCSNTANLNVVLICDKNGLRFYHTDRNTTGETVTDGDEAAALAGSPPYITIGYGS
                     LGTQRRAFHSIQDDSGAIIGYVMASVFTAHLSDSQKRIMALYLTVLAFMLLVSLLLSR
                     GVVVLLRGRLMGHEPEELLDICIRQDTVLGSLEEGLVAADPSGRVLFANQAAADLLCS
                     ERMHA"
     gene            7220..8233
                     /gene="gap"
                     /locus_tag="ACZPCR_07320"
     CDS             7220..8233
                     /gene="gap"
                     /locus_tag="ACZPCR_07320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HIR1230722.1"
                     /translation="MAVKVAINGFGRIGRLAFRQMFDAEGYEVVAINDLTDPKMLAHL
                     LKYDSSQGRYEGHTVEAGEGSITVDGKTITIYAKANAAELPWGELGVDVVLECTGFYT
                     SKAKAQAHIDAGAKKVVISAPAGNDLPTIVYNVNHNVLTKEDNIISAASCTTNCLAPM
                     AKALNDYAPIQSGIMSTIHAYTGDQMILDGPHRKGDLRRARAGAVNIVPNSTGAAKAI
                     GLVIPELNGKLIGSAQRVPVPTGSTTILTAVVKGKDVTKEGINAAMKAAATESFGYNE
                     EEIVSSDIVGIRFGSLFDATQTMVSKVDEDTYQVQVVSWYDNENSYTSQMVRTIKYFA
                     ELN"
     gene            8350..9555
                     /locus_tag="ACZPCR_07325"
     CDS             8350..9555
                     /locus_tag="ACZPCR_07325"
                     /EC_number="2.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009203119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HIR1230723.1"
                     /translation="MLNKKSVDDIQVKGKRVLVRCDFNVPLKDGKITDENRLVAALPT
                     IKKLIADGGKVILCSHLGKPKGEPKPELSLAPVAVRLSELLGQEVKFAADPEVVGPNA
                     KAAAEAMKDGEVILLENTRYRAEETKNGEAFSKELASLCDVYVNDAFGTAHRAHCSNV
                     GVTQYVDTAAVGYLMQKEIDFLGNAVNNPVRPFVAILGGAKVADKLNVISNLLEKCDT
                     LIIGGGMAFTFLKAEGKEIGSSLVDDTKLDYCREMLAKAEKLGKKILLPVDAAVAAAF
                     PSPIDAEIEVKNVSADAIPADMMGLDIGTESAKMFAEAVKSAKTVVWNGPMGVFENPV
                     LAKGTIEVAKALAETDATTIIGGGDSAAAVNQLGFGDKMTHISTGGGASLEFLEGKEL
                     PGVAAANDR"
     gene            9710..10462
                     /gene="tpiA"
                     /locus_tag="ACZPCR_07330"
     CDS             9710..10462
                     /gene="tpiA"
                     /locus_tag="ACZPCR_07330"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HIR1230724.1"
                     /translation="MARKKIIAGNWKMNMTPSEAVELVNTLKPLVANDEVDVVFCVPA
                     IDIIPAMEAAKGTNIQIGAENMYFEEKGAFTGEISPNMLVDAGVKYVIIGHSERREYF
                     AETDETVNKKVLKAFEHGLTPIICCGESLTQREQGITIDWIRQQIKIAFLNVTAEQAK
                     TAVIAYEPIWAIGTGKVATTEQAEEVCAAIRQCIGEIYDEAAAEAIRIQYGGSVSAAS
                     APELFAQADIDGGLVGGASLKPDFGEIVNYNK"
     gene            10691..11203
                     /locus_tag="ACZPCR_07335"
     CDS             10691..11203
                     /locus_tag="ACZPCR_07335"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002564678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HIR1230725.1"
                     /translation="MKKLLIVVDMQNDFIDGSLGTEEAKQIVPAVVKKIEEYQGEDCE
                     VLFTMDTHYENYLETLEGKKLPVVHCQKGTQGWELCPEIAAFEGTRFEKPSFASLDLG
                     RYVGGREYESVELAGLCTDICVISNAMLVKAVLPGTPVKVDSSCCAGVTPESHRNALE
                     AMKMCQIDVF"
     gene            complement(11215..12228)
                     /gene="aroF"
                     /locus_tag="ACZPCR_07340"
     CDS             complement(11215..12228)
                     /gene="aroF"
                     /locus_tag="ACZPCR_07340"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006443343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HIR1230726.1"
                     /translation="MIIIMKPGASEENIRNVAGQIEEKGLTVHLSHGTEVTIIGVVGD
                     KSKLQGSNLEIADGVDKVVAVTESYKLANKKFHPEPSSVSLSNTSVGPENLTVMAGPC
                     AIESSTQLMETAFAVKKAGATVLRGGAFKPRTSPYSFQGLETEGLKYMKEAREATGLS
                     VICEVTSARAIEDAVKYVDLLQIGARNMQNFELLKEAGKTGLPILLKRGLSATIDEWL
                     NASEYIMAEGNSNVILCERGIRTFETATRNTLDLSAVPVLRQKTHLPIIVDPSHATGV
                     RAYVEPMAKAAVSAGADGLMIEVHPCPEKALSDGPQSLTFQEFDSLMNRLRPYAALEG
                     RTL"
     gene            12629..14173
                     /gene="gpmI"
                     /locus_tag="ACZPCR_07345"
     CDS             12629..14173
                     /gene="gpmI"
                     /locus_tag="ACZPCR_07345"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009246311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HIR1230727.1"
                     /translation="MSKKPTVLMILDGYGLNDSCDHNAVCEAKTPVMDQLKSQCPFVK
                     GYASGMAVGLPDGQMGNSEVGHLNMGAGRIVYQELTRITKSIQDGDFFEIPEFLQAVA
                     NCKQNGSALHLFGLVSDGGVHSHNTHIYGLLDLAKRNGLEKVFVHCFLDGRDTPPASG
                     KSFVAELEEKMQEIGVGKVASVMGRYYAMDRDKNWDRNKLAYDVMTKGEGNRADSAQA
                     AIQASYDAEKFDEFVLPTVIEENGAPVGLIQDGDSVIFYNFRPDRARQITRAFCDNEF
                     TGFEREKHLNLTFVCFTDYDETIENKLVAFKKESITNTFGQFLAANHKTQARIAETEK
                     YAHVTFFFNGGVEEPNKGEDRILVPSPKEVPTYDLKPEMSAPAVCEKLVGAIKSGDYD
                     VVIVNFANPDMVGHTGVEAAAIKAIEAVDQCIGKAVDAVKEMGGVMFICADHGNAEVM
                     VDPETGKPWTAHTTNPVPFILVGADASYGLREGGCLADIAPTLIELMGMEQPKEMTGK
                     SLLIRK"
     gene            14204..15067
                     /locus_tag="ACZPCR_07350"
     CDS             14204..15067
                     /locus_tag="ACZPCR_07350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015515320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008289 - lipid binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HIR1230728.1"
                     /translation="MKTAIVTDSNSGITQKQGEELGIYVLPMPFMVDGRTYLEGVDLT
                     HQEFYEKMNGGADISTSQPSPDSVMKLWDGLLTTYDEIVHIPMSSGLSSACQTAMVLA
                     QDYEGKVHVVDNHRVSVTQRQSALDALELAKAGVSGADIKRKLEETQGDSVIYITVDT
                     LKYLKKGGRITAAAAALGTLLKIKPVLIILGKKLDAFSKARTTKQAKNIMISAIQKDL
                     KERLGDETCTKTHIEIAHTQNDEAAQAFSEELRELFPEADIYLDPLPLSIACHIGPGS
                     LALAATRRMEA"
     gene            15068..16522
                     /locus_tag="ACZPCR_07355"
     CDS             15068..16522
                     /locus_tag="ACZPCR_07355"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002590098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1230729.1"
                     /translation="MWGGVFKKKTRREARHAVSMRLPLLFCILVFTIVPLLTQSAMLT
                     STLRQSQVEDTMIHAQNKCLILVNKMLSSDYANSGAKNPIMDTELAVTAELFNGRILV
                     ADRNFKIVKDTYGLAEGKFNITEEVLKAYSGETQSSYNRKKDYFSLAFPIQEKEKNGT
                     ADGVLLFTASTERIELLDSQISEKMFFFQIVILWLAAGLAFLAAGVLIRPFTRLRKVL
                     GIVADGDLEQDIMVGDYKETREISDAVSRTLGKLKAVDQSRQEFVSNVSHELKTPITS
                     IRVLADSLMGMEDAPAELYREFLSDISDEIDRESKIIDDLLTLVRADKSNAELNVATA
                     NLNGLLEQILKRLRPIAKKRNIELVFESIRQVSADVDEVKLSLALTNLVENAIKYNHE
                     DGWVHVTLDADHKFFYVKISDNGIGISQEAQEHVFERFYRVDKARSRETGGTGLGLAI
                     TKSIVLMHQGAIKLQSREGEGTTFTVRIPLNYIP"
     gene            16595..17563
                     /locus_tag="ACZPCR_07360"
     CDS             16595..17563
                     /locus_tag="ACZPCR_07360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003508195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HIR1230730.1"
                     /translation="METAEKRTGRGKKAAFLLAAALLLAVFCTGCKGKQKEENEASGS
                     GEYQIYYLDASGLKLSPCSYKTETEDTEQLLGELAGQLLTPPADTEYQPALTDKTKLL
                     GMKKNDNVLYLDFSKEYNSIEPIREILCRAAFVKTLTQAEGVEFVAISCEGQPKLDSA
                     GNPVGALGKSDFVEGVTDINSYEQAELTLYFSNEEGTALIPETRTVVHSANTSLERLV
                     VEQLVAGPLDDAVNPVLPKETKILNVSVAENICYVNFDSSFLAGVPNTSEKLTVYAIV
                     DSLTELQTVNKVQITVNGSQDIMYRDAIPLNQPFDRDEQYILNQEG"
     gene            17672..20128
                     /locus_tag="ACZPCR_07365"
     CDS             17672..20128
                     /locus_tag="ACZPCR_07365"
                     /inference="COORDINATES: protein motif:HMM:NF015714.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HIR1230731.1"
                     /translation="MVKGGAAAFAAALVFCALFADTGRTAGSVRGLFSMETGFLKSGT
                     GSFAAVWILAAAALLGAARMGGGLQEETIVKEEGNPGFSDLTARAEGTVEAIQEKNGR
                     VSVQLKHVKTVVRKTDEVRQQGKREYALKRLLVYLPPEDMEIGEILPGVKILCTGELE
                     RFEPARNEGEFDYRLYYRSRDICCRMSAKKAEITEHSVWLLQAVTYRIREQAKKLLEQ
                     YCTETDAGLLAAVLLGDKTRMNEEINELYQKNGIAHLLAVSGLHISLIGMGVYRLLRR
                     LGLGFGTAGFWVGGLLFVYGTMTGFGPSVFRACLMLACSFWAAYLGRTYDLLSAMALA
                     AVCLSLENPFVIFTGAFQLSFGAVFAIGWAGTELADRLRCQKSWEKALAVSLAIQLVT
                     GPIVLYHFFEYPLYGIFLNFLVIPLMTYVAGAGMAGLLMGMAGVFAVSFIPGPTALFL
                     KKMLDIGAVGSMGTCHYIFMVYEMLCRAAEKLPCSSLILGRPKLWKLAAYYAALAVFL
                     ACAGSRGRRWEAEKEGQEEKAERKGKEHIKTWGILFALLAFLLHRSVSGLRVDFIDVG
                     QGDGILLETREQVILVDGGSTQIKKLGEQRLEPLLKSRGIRNIDMVFVSHGDQDHISG
                     ITWLLEEDTGIEIGRLFLPFPGKGEEVYERLESTAEKRGVKTDYICAGDFVQSGKLSL
                     SCLYPYRDTLSSDRNDHSEVLLAEYGDFSMLLMGDLGAEGEAEIAEQWNKNRQVQILK
                     AGHHGSSTSSSEQFLDTVHPRIAVLSYGKDNSYGHPHPEVIERFDERGIARWATEEQG
                     MITIRTDGEEMEIQGFIQNR"
     gene            20318..21289
                     /gene="holA"
                     /locus_tag="ACZPCR_07370"
     CDS             20318..21289
                     /gene="holA"
                     /locus_tag="ACZPCR_07370"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003508192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HIR1230732.1"
                     /translation="METLNQDIKSGNFKRFYLLFGEEEFLKQSYKKRLRQAVAGNDTM
                     NYNYFEGKGLDVRELISLANTMPFFSDRRLIMVEDSGFFKAVSDELVEALPDIPDTTC
                     IVFAESAVDKRNRLYKKVKELGSAVELKRQSASQLAVWAGRILAQNGRKITSADMNFF
                     LERTGDDMETIRTELEKLISYTMGQEVVTREDIEAVTTVQVTNKIFDMVTAIVTGKTK
                     TAMDLYEDLLTLKEPPMRILFLIARQFNQILLVKEMMASGNDKSAIASKLKIPPFVAG
                     KLMPQARTFTREQLAGCVEACVEAEEAVKTGQLGDRLAVELMIMRKY"
     gene            21336..24596
                     /locus_tag="ACZPCR_07375"
     CDS             21336..24596
                     /locus_tag="ACZPCR_07375"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: protein motif:HMM:NF020044.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HIR1230733.1"
                     /translation="MFTESDIRKQTDRGITYIKGYKLYTNGSVLGLDEEYSEEDRSCF
                     VAGSVEGSYGNEYDVSIALDDNEEIKSYSCTCSAFETYPGMCKHCVALALEYLYSRED
                     PEREEEFEDNPLGFRKNRTDTEILDVVAAFSLRRRMKEQTACGKIEIIPELQEISRYC
                     YYGNRGNFKLTFKIGLEDGKQYVLKNVSDFLGHIYREEMHSYGKQLAFVHSKNAFTET
                     AWKYIELMEQARRESSARYEELGREIILTPKLWDAFFEINQGSSMEYIAITRHKRELH
                     FLKQEPPVRFRLIAEEEKGFQIKIPPLQLIRGGDRPYVKLQQSIYQCSDDFYAGAGEF
                     LKLADEKKETSYHIARKDMPAFCGAVLPELDELGIADRGKLDLGEFQPKKAEISFYLD
                     EENGRVTLKTMGIYGDAAYNLLKPTDFSGEYRDRTKEIRVQNLIRSYFSLEDIGEGIL
                     YFESDDHDRMYHLLNSGISQFEAEGTVYATDRIKGRKLLKNPRTQVGVAIKSGLLELS
                     VQSSEFLPEELAGILDSYRKKEKYHLLKSGSYIGLEENSVATVAELLDGLGVSGKDFD
                     EGRLEIPRFRACYVDQMLSQKEGQLQAERSSDYKAVIRNMKNVEDSDYQTPETLRDVL
                     REYQKFGFRWLNTLADLGFGGILADDMGLGKTLQTIAYLLYRKQQRKTECPHLIICPA
                     SLVYNWEREIERFAPELKTAVIAGNAQQREEMIKGDQKADIWITSYDMVKRDISLYKE
                     RQFDTEVIDEAQNIKNHGTLAAKAVKKIRAEVRFALTGTPIENRLSELWSIFDFLMPG
                     ILGTYEKFRKGYELPIVQNQDERLAKRLKRMISPFILRRVKSEVLKELPDKLEQVVYA
                     RMGEEQRKIYESHALRLMESLEKQSEEDLQKGKLQILAELTRLRQICCAPEMLYENYG
                     EISCKVETCMELIHQAMSGNHKVLLFSQFTSVFPILEKRLMQEKIPYYELTGQTSKEK
                     RMQLTEQFNSGDVPIFLISLKAGGTGLNLTAASIVIHFDPWWNLAAQNQATDRAHRIG
                     QEQQVTVFKLIAQNTIEEKIVKLQQEKEKLASQILDGEGMAVSALTKNDFMEILEF"
     gene            24977..25498
                     /locus_tag="ACZPCR_07380"
     CDS             24977..25498
                     /locus_tag="ACZPCR_07380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006354 - DNA-templated transcription
                     elongation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0140673 - transcription elongation-coupled
                     chromatin remodeling [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination NusG
                     family protein"
                     /protein_id="HIR1230734.1"
                     /translation="MSWYVLQCRAGREAEMVNSLNQHLSREALEEAFYFQSERLWRSE
                     GSWKRQKKELFPGYVFLQSENPGLLSEALEEYRQIVRIMEEPGYLISVYPEEEEYLRG
                     LCGTDHFLPLSYGYKDRVTGCSRITKGPLAGRENQVKIFDWHRRFARMEISIENRKAS
                     VWAGLALDEAAVS"
     gene            25745..26290
                     /gene="loaP"
                     /locus_tag="ACZPCR_07385"
     CDS             25745..26290
                     /gene="loaP"
                     /locus_tag="ACZPCR_07385"
                     /inference="COORDINATES: protein motif:HMM:NF033641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antiterminator LoaP"
                     /protein_id="HIR1230735.1"
                     /translation="MWYVIQTETGREEEVLSLMRRLLDKRLCSRYMILEAEWPKRSGG
                     QWLLLRKAMFPGYIFVETEEAEEVFFQLKQIPKLTKILGNEKFEFVPLAEEEIQFLYK
                     ISKTAEKNGTEQRLLVYPSRITVDKAGTINVISGPLKEFEKEILRVNLHKRYAVVKVK
                     MLGEKTVLFGIVMEKDRERRS"
     gene            26399..>26591
                     /locus_tag="ACZPCR_07390"
     CDS             26399..>26591
                     /locus_tag="ACZPCR_07390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HIR1230736.1"
                     /translation="MEKKRIFLASPTMNGHEMEYIQEAFDTNWVAPLGKNVDEFEKEL
                     AAYAGVSHAAALSAGTAALH"
BASE COUNT         7338 a         5668 c         7377 g         6208 t
ORIGIN      
        1 tggaataaaa ccatacaggt tttacttttc agcatgattc aaaaaatttt tttaaatttt
       61 ttgaaataga tgcaataaaa caaaagtctg ttgcattaac taattgaacg gatgaaaatg
      121 atttctgttt ctggcagaca gaaggtatac acgaacacat atcaagttac tcgaaattcc
      181 ttgatgcatt acaccccgtt acatgtatcc ttctaaagca gtacagaaaa ttttcaaata
      241 caggcggcag catccaacca atccgccgcc tgtaggcgaa taaaaaagac cggtctgaga
      301 tatcagctcc ggtctttttt attcgccttt tctttgttta aaagagttga catttcatgg
      361 aaaacgcgat ataaaagtca ctgcacaagg gggagaaacg acatgaaaat ggaaaatgat
      421 ttagggcggg acgatatccg ccttttagtg atgcggatcg cgcttccatc catgctggcc
      481 cagtttgtca gcgtactcta cagcgtggta gaccgcatgt atataggaaa tattccggag
      541 ataggggaga cggccctggc gggagtcggc gtctgcgggc ctattgtcac tctgattaca
      601 gcctttggtt ccctggtggg aatcggagga gcgccgctta tgagcatccg cctgggagaa
      661 aaggatgaga agggagcttc ccagattttg gccaactgct ttctgctgct ttctgtgatc
      721 tcagttgtca tcaccgctct gtctctgctc atgaaaaata agctgttagt ctggtttgga
      781 gcaagcactt cgatttttcc ttatgcagat gattatatta ccatttatct gctgggaacc
      841 atatttgccc tgctttcgat tggaatgaac cagtttatca tctgccaggg ctttgcaaag
      901 gtggccatga agtctgttgt actgggagcg gtggtcaaca ttgccctgga tcctgtattt
      961 atttttgcct gcggcatggg cgtaagggga ggggcgctgg ccactgtgct gtcccagatg
     1021 gcttcggcgg gctatgtact tttattttta tttggaaaaa aggttcccgt gcccattacc
     1081 ttcggcggct atcagtggag aatcatgaag cgggtgattc tgctgggact gtctccgttt
     1141 ctaatcatag catttgacaa tgtgctgatt attgccatga acgcctcgct gcagcatttt
     1201 ggaggggcgg agggggatat gcttctcacc tgcaacacga ttgtccagag ctttatgctg
     1261 atggtgacta tgcctttagg aggaattaca ggcggaaccc agacgattct gggctataat
     1321 tttggagcca gacggtctga cagggtgctg gccgcccagc agtatattgt gattctgtca
     1381 atggcgttta cagcagtgat gtttgtcatt gcccagactg taccccacta ttttgtccag
     1441 atctttacaa gggatccgga atatgtggag ctgactgtga gggcgatccg gatctttact
     1501 ctgggaatta ttcctctggc agtccagtat gagattgtgg acggctacac aggcatggga
     1561 atcgcgccga tagcaatttc cctgtcaacg gtgagaaaaa ccctgtatct tctgggcgtt
     1621 gtcctgattc ccatgttttt cagcgtggag gcagtgttct atacagagcc gatttctgat
     1681 tttctgggaa cggcagtgag cattaccgtg tatctgatga ctatgaagaa aattttaagg
     1741 cgcagggaaa atggggagat gtaggagact cctttggagt gcggatttga gctgacacaa
     1801 gtcgcagagc cttatctggc ggagaatatg ggaagtccag actagggcag gagtccctgc
     1861 tcctggtaga aacgttcagc tcccgggtgg agcggtatgg gaagttcact gtacatgaag
     1921 ccgtcttcag acataggctt caggagaacc tgtttttttc caaggggctc tcgtctggaa
     1981 tagaggatag aagtcagctt atagaccagc tcttcatcca ggctgtcgtc cacacagatt
     2041 aggcatttca cgccaaagga gtctatatct tccgcttgtc cctcataggt tccggcagga
     2101 attctggtcg gataatagaa gttgttttca gacagaatct ggttcagttc gctggctgtg
     2161 tactttaaaa gtcttgacgg agtctggaca gaaagattat acagcccttc tatgggagtt
     2221 ccggcaaagc cgtgaacagc gtccagagta ccttttaaaa cctcctccgc tccgtagcca
     2281 atgcctcccc gtgtttcaat ttctgtgttt tcccgggtta tgtcaaacag gtcgaagaca
     2341 atgcgggcgg agagatccgt gttggatgcc tctggaccta cagagacgcg ttttcctttc
     2401 agatcatgca cataaaacag ggaagaagag ttcagagcca tccagttgga aatactggaa
     2461 tagacagctc cgatagttcg aagtcctgtc tgagggtcag ttgaaaattc gtgagttcca
     2521 tgaaaggccg cataggccgc atcaccgctg acaaggccca gatcaatctg tccgtcgctc
     2581 agcatctgga tgttggtgta ggagccgttg gaggcgcata tattaacatg gatatggtgg
     2641 gaggtggttt caatggcctc ggcgatggcc tcgccggctg ggtacatgct tcctccgctg
     2701 tcggctgtcc cgatagtgag aacagtgatc gcgccggccg acggttccgt actgctggag
     2761 agggaagcgg aacggccagt cagcgagcag gaacagagaa gcagagccgc ggtaaagata
     2821 cctatggcag tgcgggcaga tataaacctg ggatgtctcg gatggttcaa tgggggcctc
     2881 ctgtttttat ggcagaacag ttctgaaaaa tagatttttt ctgctctgct gtaaggtgaa
     2941 atattattca taattataac ataaaattaa cattcagaaa aggaaaaaca ggattcagga
     3001 taaatattat gtgatttcct gtaaagacaa aggaaaaagc agaaaaaaga gaatcaggga
     3061 atcgcgtcga agtcaaaagg agcgtccaca gccatacaga cggccgcggg cgctcctcta
     3121 tctactgacg atatcagaca gaatatggat tcaatattta tttccctatg attccaccga
     3181 aaacagagag gaaaatcgga ttgtagatgt cgtcaatgat gacggcgaaa gatgggtaca
     3241 gtacccatgc aacattatgc cagccatagg catccataac agctttctcg tttgcaacgg
     3301 cattcgggcc ggagccgcag ccccatccgc agtttccggc agccatgact gcagcgccgt
     3361 aattgcgtcc gaacatattg taggagataa agatagcaaa cagggctatt aatactgcct
     3421 gaacaagaag gataattccc atctgtcccg caacaggagc cagagccgta atatcaattg
     3481 tcatcagaac cagagccaga tacagttcga ggaacatgtg ctcgatagca tctacctcag
     3541 gcgtgtaaaa tttgatattc atagcctcca tcacatttct cgcaatagcg ccggcaaaga
     3601 ggcagccgat gaatttcggc atctcgatca taggaatgtt gtcgaggatg cagtagatcg
     3661 gcattccgag agcggcaacc agcaggcaca tggcaaacat ggaaatcatg cggctgttgg
     3721 ttagcgggat tacttcgcct gtctttgcgg actccggctt gtcgttgggg tcagccttta
     3781 atttgtggtg tgtgatcagg aaggcagcca caggaccgcc gattaaggaa cccatgatat
     3841 ttccgcaggt tcctgctgcc acgccgatgg tagtggcgtt gggggctccc cactcctcga
     3901 agatcgcacc gaaagcggat gcagttccaa caccgccgga catggatgcg gaagagcact
     3961 gaagggctaa cagtgggtga aggccgatgg catttcccac cagtacgccg acaatatcct
     4021 gcaaggtgat taaaagacat gcggcgacgg caatcatgat gcacagtttg cctccggcat
     4081 gtttaatcat tttcaggctg aaaccgaagc cgacgcacag gaaaaacagg ttctgacaga
     4141 gatcctgcat aattttcgta tcaaaggaga tgccgataat tcctgcgcct ttgatgacag
     4201 acacgatgat ggaaaagatg actcctgaca caacaggagc ggggattgca tacttgcgca
     4261 gaagcgcaga atgtgcaacg atcgcgcggc ctgcaaagat aacgatggcc gcgaagccca
     4321 gggtggtcaa atactcgaac ttgaacgacg ccacagcgcc gtcggcagca ggagtatatg
     4381 taccgaaata gcttaaaata gcttccataa acaacagttt cctccgtttc tttaatatta
     4441 taaatatgtt aaatatttat aaacgaagta taaagaaaca gaaaacgaaa gtcaatttat
     4501 gtaattaatg acaggttttt gtaactaaag tacatggcag gagcaggtat atttgatgga
     4561 aggccgaccg ccggtctgat aatccacgga gcttataatc tcccccatct ccagcatata
     4621 gttcacgtaa cggcggatgg taatgcggga caggaatacc tgttcggcaa tctgctcgct
     4681 ggaaaagaac tctccgggcc ggttttgcag gaaattccgg atcagattca gcgtggtttc
     4741 gcttaagccc ttggcaagtt ccgtctgaaa ggaggaggac ggctgcatat gagagagcag
     4801 cctgtcaatc tctgcctgat ttagctcagg agagccgtcc aggcagcttc tggtctgcgc
     4861 aaagcgagag agggcctggc gaaatcttga ccgttcaaag ggcttaacca gatagtccag
     4921 cacgcctcgg gagagcagct cctggacaat ggcagagtcg ctggcagagg tgaccatgat
     4981 aacagagggc gcctttccca tgctgtgcag ccggtcaata aattcttttc cggtcatcag
     5041 tggcatgtag tagtccagga taatcagatc cgcctcctct ctgctcagcc aggaaagcgc
     5101 atcctgaccg gatttaaagc tctgctttac agaaaaggag ggctccaact ccacatactg
     5161 gcggttgata gaagccacca ttggatcatc ctctacgata attactgaat acatgtttcg
     5221 ttctccttcc gtgtgaaggc gagggttatt atcgttccct ccccttcctc tgtctcaatg
     5281 gtaagttcgc cgccgcggcg ggcggcaatt tcctttatca ggaacagacc gaggcctctg
     5341 ttgtctccct ttgtggaaat acctttgtcg cagatacgcc ccgccagctc cctgcagata
     5401 ccacgccctg tgtcctcgca gacaatcagg ttaaaatccc tccggcagaa aagggagagt
     5461 ttgatttcct ttatggccct gtgtgcattg gccgggtctg ccagctcctc cacggcattt
     5521 tccaggagat ttcccactgc agtaatcatt tcctcgctgg gaatcagcaa atcgtgctcc
     5581 aggcagatac tgtcagggga gagggacagg cggatgccaa gctccgccgc gtgcatcatt
     5641 tttccgataa tcagggcaca gatggaagat acgcggatgc gctcggcagt ttctctgact
     5701 gcctggctgg atacaaggct gctgttcatg ataaaggtga tagccttttt tgtttctcct
     5761 gtctgcagat atcccaggat gacgtggagt ttgttcataa actcatggtt gaaggcacgc
     5821 agcgtatcca gggttgcgcg ggttccggac agctcgtccg acattctgag catctcagtc
     5881 ctgtcgttca gaaccatgag gacgcccttt acagaatcct tttttattat gggaattgcc
     5941 ttaataagca gagtgcggct gcccacattg gtaatcaggc tggagacgga gaaatgggat
     6001 gtatctgccc tattccggag agcgtccctg gacagcaggc tggaacagtc tgtatccgga
     6061 aacagtgcag acagctgttt ttcttccaga ctgtcaggca tgcatccgct cgctgcagag
     6121 cagatcggct gccgcctgat tggcaaacag caccctgccg gagggatcgg cggctacgag
     6181 cccttcctcc agggagccga gaacggtatc ctgacggatg cagatgtcta aaagctcctc
     6241 aggttcgtgg cccatcagcc ttccccggag cagaaccaca acgcctcttg agagcaacag
     6301 gcttacaaga agcataaaag ccagcactgt caaatacaga gccataatgc gcttctggct
     6361 gtcagacagg tgtgcggtaa aaacggaggc catcacatac ccgatgatag cccccgagtc
     6421 atcctgaatg gagtgaaagg cacggcgctg ggtgccgaga gagccgtagc cgatggtaat
     6481 atagggtggg cttccggcca gggccgccgc ctcgtctccg tctgtgaccg tttcaccggt
     6541 agtattgcga tcagtgtggt aaaagcgcag tccgtttttg tcacagatga gcaccacgtt
     6601 caggttggcc gtgttgctgc acagggagtc gagatccttc ctgacggaat cagagggata
     6661 acccatttgg agcatgtcga ttacctgagg catggaagcg atgtaggcgg caagtccgct
     6721 gatagtggag tccacctctt ttctctgcct ggtaatatca tagtacatgg taatgccgag
     6781 ggaaagcagc aggagaactg cagagacggc aaaaaagctg cgggagagag tcgtctccag
     6841 agtggacttt ttttgcttct tacaggtatt gccgtgagtc ttcccagcgg aatttttcat
     6901 tctgtaaaga tttaaaatac ggaaattcac ttgtttcaca tcctgttttt cagagtatgg
     6961 gtataattta cccgccagtt agagatgata taaattatat agaaaaggaa gcagggatgc
     7021 aacacaaaaa ggaagcagca gttccttgac acagatactg tacaaaagca ggtaaaaggg
     7081 cggtgtaaat tttataaaag ttcaaaaaaa cccttgctat ttctggaaga attaggtaca
     7141 atacaaaata ggttgattat tatttaacaa tcctattaac taaccatcat gaaataaaat
     7201 tcttaggagg aatgaaatca tggcagtaaa agttgcaatt aatggttttg gccgtatcgg
     7261 ccgtctcgct ttcagacaga tgtttgacgc agagggttac gaagtagtag ctatcaacga
     7321 tttaacagat ccgaagatgt tagctcactt attaaaatat gactcttccc agggcagata
     7381 cgagggacat acagtagagg ccggagaggg ctccatcaca gttgacggaa agactatcac
     7441 aatctacgca aaggctaacg cagcagagct tccttgggga gagcttggcg tagacgtagt
     7501 tctggagtgt acaggtttct acacatccaa ggcaaaagca caggctcaca tcgacgccgg
     7561 cgctaagaag gtagttatct ctgctccagc aggaaacgat ctgccaacta tcgtttacaa
     7621 cgtaaaccac aacgtattaa caaaggaaga caacattatt tctgcagctt cctgtacaac
     7681 taactgcctg gctccgatgg caaaggctct gaacgactac gctccgattc agtccggtat
     7741 catgtccaca atccatgcat acacaggcga tcagatgatc cttgacggac cgcacagaaa
     7801 aggcgattta agaagagcaa gagcaggcgc tgttaatatc gttccgaact ccacaggagc
     7861 tgctaaggct atcggccttg taattcctga gttaaacgga aagttaatcg gttccgctca
     7921 gcgtgttccg gttccgacag gttccactac tatcttaaca gcagttgtta agggcaagga
     7981 cgtaacaaaa gagggaatca acgcagctat gaaggcagca gctacagagt ccttcggcta
     8041 caacgaggag gagatcgtat cttccgatat cgttggtatc cgcttcggtt ccttattcga
     8101 cgctacacag accatggttt ccaaggtgga cgaggatact taccaggtac aggtagtttc
     8161 ctggtacgac aacgagaact cctacacaag ccagatggtt cgtacaatta agtacttcgc
     8221 tgagttaaac taattgcgga tttccagttc gtttgacgaa gagagaatag gattcacgta
     8281 aaaaggtggt ccggtccgtc ctggaccggg ctgccttttt tggtaaaaaa atgagaaagg
     8341 agcatgttca tgcttaataa aaaatctgtt gacgatattc aggtaaaggg aaaaagagtg
     8401 ttagtgcgct gcgattttaa cgtaccgtta aaggacggaa aaattacaga tgagaaccgt
     8461 ctggtagcag cccttcctac tattaagaag ttaattgctg acggcggaaa agtaattctc
     8521 tgctcccatt taggaaagcc gaagggagag ccgaagccgg agctttcctt agcgccggtt
     8581 gcagtccgcc tttctgagct gttaggccag gaggtaaagt ttgccgctga tccagaggtt
     8641 gtaggaccaa acgcaaaggc agctgcagag gctatgaagg acggcgaggt tattcttctg
     8701 gagaatacac gctacagagc agaggagacc aagaacggag aagcattcag caaggaactg
     8761 gcttcccttt gcgatgtata tgtaaacgac gcgttcggaa cagctcacag agcacactgc
     8821 tccaacgtag gcgtgacaca gtacgtagac acagcagccg taggctactt aatgcagaag
     8881 gagatcgatt tcctgggcaa tgcagtcaac aacccggtgc gcccgttcgt agctatcctg
     8941 ggcggagcta aggtagctga taagttaaac gtaatctcca acctgcttga gaagtgcgat
     9001 accctgatca tcggaggcgg tatggcgttc accttcttaa aggcagaggg caaggaaatc
     9061 ggaagctcct tagtggacga caccaagtta gattactgcc gcgagatgct cgcaaaggct
     9121 gagaagctgg gtaagaagat cctccttcct gtagacgcgg ctgtggcagc agcattccca
     9181 agcccaatcg acgctgagat cgaggtgaag aacgtatctg cagacgctat cccggcagat
     9241 atgatgggtc tggatattgg aacagagtct gccaagatgt ttgcagaggc agtaaaatcc
     9301 gctaagacag tggtatggaa cggaccgatg ggcgtattcg agaatccggt tctggctaag
     9361 ggaactatcg aggtggccaa ggctctggca gagacagacg ctactactat catcggaggc
     9421 ggcgattctg cagcagcagt aaaccagtta ggcttcggcg ataaaatgac tcacatctcc
     9481 acaggaggcg gcgcatcctt agagttcctg gagggcaaag agcttccagg cgtagcagcc
     9541 gcaaatgacc gatagcactt agcgaggtgt tttcgagctt agtgcgaagg tcgttcccga
     9601 atctagacga ggttctttcg aggcgtagct gagggaacat acccgatagc acttagcgag
     9661 gtgttttcga ctgaaataaa tataagaata aaagaggagg aattctgaca tggcaagaaa
     9721 gaaaattatt gcaggaaact ggaagatgaa catgacgcct tccgaggcag tagagcttgt
     9781 aaatacatta aagccattag tggcaaacga cgaggttgac gtagtattct gcgttccggc
     9841 tattgacatt atcccagcga tggaggctgc caagggaact aacatccaga tcggcgctga
     9901 gaacatgtac tttgaggaga agggagcttt cacaggagag atttccccga atatgctggt
     9961 tgacgcaggc gtaaagtatg tgatcatcgg acattctgag agaagagagt actttgcaga
    10021 gacagacgag actgtaaata agaaggtatt aaaggccttc gagcacggcc tcacaccaat
    10081 catctgctgc ggagagtcct taacacaaag agagcaggga atcaccatcg actggatccg
    10141 ccagcagatt aagattgcct tcttaaacgt aactgcagag caggctaaga cagcagtgat
    10201 cgcttacgag ccgatctggg ctatcggaac aggaaaggta gctaccacag agcaggctga
    10261 ggaggtatgc gcagcgatcc gtcagtgcat cggcgagatt tatgacgagg ctgcagcaga
    10321 agctatccgc atccagtacg gcggttccgt atctgccgct tccgctccgg agctgtttgc
    10381 acaggcagac attgacggcg gactggtagg aggagcttcc ttaaagccag attttggcga
    10441 gattgtaaat tacaataaat aagagacagt gagaagagag gcacggcgtt ccgggaacga
    10501 tcctgtgcct ctttcttcta ttctgccata aacgcgggaa gatttttgtc cgggattttc
    10561 cagaaaaaag acagaaataa ttaagaggtt tttcattgat acaaaaaggc tggtgtgata
    10621 tactgttctc taattttaac aaatatagat gaaaaggatt tcaggaggaa atagaatgga
    10681 gaatagcaat atgaaaaaac tgctgattgt ggtagatatg cagaatgatt ttatcgacgg
    10741 ctctctgggg acagaggagg caaaacagat tgttccggca gtggtaaaaa agattgagga
    10801 atatcaggga gaggactgcg aggttctgtt tactatggat actcactacg agaattatct
    10861 ggagacgctg gaaggcaaga agcttccggt ggtacactgc cagaagggga cacaaggctg
    10921 ggagctctgc ccggaaatag ctgcttttga gggaacgcgt tttgagaagc cgtcctttgc
    10981 aagcctggat ctgggaagat atgtaggagg aagagagtac gaatctgtgg agctggcagg
    11041 actctgcaca gacatctgcg tcatttcaaa cgccatgctg gtaaaggcag tcctgcctgg
    11101 aactcctgta aaggtagatt cttcctgctg tgcgggagtg accccggaga gccatagaaa
    11161 cgctctcgag gccatgaaaa tgtgtcagat tgacgtgttt taagtaataa aaaactacag
    11221 cgtccttccc tccagggctg cgtacggtct gagccggttc atcaggctgt caaattcctg
    11281 gaaggtgagg gactgcgggc cgtcggagag agctttctcc gggcatggat gaacctcgat
    11341 catcagtccg tcggcgcctg ccgatacggc ggctttagcc ataggctcca cataggctct
    11401 cacgccggtg gcgtggctgg gatccacgat aatgggaagg tgggtcttct ggcgcagaac
    11461 cggaacagcg gagagatcca gcgtatttct ggtagccgtc tcaaaggtgc ggatgcctct
    11521 ctcgcagaga attacattgg aatttccctc tgccatgatg tattcggagg cattgagcca
    11581 ctcgtcgatg gtggcggaaa ggccgcgttt taaaaggatg gggagacctg tctttccagc
    11641 ttccttcagc agctcgaaat tctgcatgtt tcgtgcgccg atctggagca gatctacgta
    11701 ttttacagcg tcctcaatgg cgcgggcgct ggttacttca cagatgacgg aaagtccggt
    11761 ggcttccctg gcttctttca tatattttaa tccctctgtc tccaggccct ggaaagagta
    11821 gggggaggtg cggggcttga aggcgccgcc gcgcagcaca gtggctcccg ccttctttac
    11881 ggcaaatgcc gtctccatca gctgggtgga actttcgatg gcgcagggac cggccatgac
    11941 agtcagattc tccggcccca cagaggtgtt ggacagggat acggaggacg gctccggatg
    12001 aaattttttg ttagccagct tgtaggactc tgttacggcc acaactttat cgacgccgtc
    12061 ggcgatctct aagttggaac cctgaagctt tgatttgtct cctactacgc cgatgatggt
    12121 cacctcggtt ccgtgggaga gatgaacagt caggcctttt tcttcgatct gtccggctac
    12181 atttctgata ttttcttcag aagcgccggg tttcataata ataatcatat ctgattcctt
    12241 tctttcgcca gagtttaggc gaatgcagcg aataaatttt caggcaatga aacgatgatg
    12301 tttcgtcgtt gtacagctat gtggcctatt gtagagcaga aatgtgcttc tgtcaatgat
    12361 ttattacgtt aaacttttaa aacttaacgc aaaacagaaa acgaaagttt tatggagggc
    12421 ccggcatgaa tttgaaagcg gccggactgg gagcagaaac tggagagctt tgttttgaca
    12481 aaaatttgac actatcccat tgaaacttaa atagaaatca tgtagaataa ggaacggaaa
    12541 gacttttaca aatttgaaca ttaacgatac agccttctga gcaccgtttc ggcgcttggg
    12601 acaggcagag acagtgaagg agaatattat gagcaaaaaa ccaacggtac tgatgattct
    12661 cgacggatat ggattaaatg acagctgcga tcacaatgca gtttgtgagg caaagacgcc
    12721 ggtgatggat cagttaaaga gccagtgccc gtttgtaaag ggctatgcca gcggaatggc
    12781 agtgggactt cctgacggcc agatgggaaa ctctgaggta ggccatctga atatgggagc
    12841 cggacgtatt gtgtaccagg agctcacaag aattaccaag tccatccagg atggagattt
    12901 ctttgagatt ccggagtttt tacaggcagt ggcgaactgc aaacagaacg ggtctgctct
    12961 tcacctgttt ggccttgttt ctgacggagg cgtacacagc cacaataccc acatttatgg
    13021 tcttctggat ctggctaaga gaaacggcct tgagaaggtg tttgtacact gctttttaga
    13081 cggccgcgat acgccgcctg catctggaaa gagctttgtg gcagagcttg aggaaaagat
    13141 gcaggagatc ggcgttggaa aggtagcttc tgtgatgggc cgctattacg ccatggacag
    13201 agataaaaac tgggacagaa ataagctggc ttacgacgtt atgacaaagg gagaaggaaa
    13261 ccgcgcagac agcgcccagg cagcaatcca ggcttcctat gacgcggaga agtttgacga
    13321 gttcgtgctt cctactgtta ttgaggagaa cggcgctccc gtaggcctga tccaggacgg
    13381 ggattccgtg attttctata acttccgtcc agaccgcgca agacagatta caagagcttt
    13441 ctgcgacaat gagtttacag gctttgagcg cgaaaagcac ctgaacctga ctttcgtatg
    13501 ctttacagat tatgatgaga ccattgaaaa taagctggta gctttcaaga aagagagcat
    13561 taccaatacc ttcggccagt tcctggcagc caaccataaa actcaggcca gaattgcaga
    13621 gacagagaaa tacgctcacg tgaccttctt ctttaacggc ggtgtggagg agcctaacaa
    13681 gggagaggac cgcattctcg ttccatcccc gaaggaagtt ccaacctacg acttaaagcc
    13741 tgaaatgagc gctcctgctg tctgcgaaaa gctggtggga gctattaagt caggcgatta
    13801 cgacgtagtg attgtaaact ttgcaaatcc tgacatggta ggccacacag gcgtggaagc
    13861 tgccgccatc aaggcgattg aggcagtaga ccagtgtatt ggaaaagcag tggatgcagt
    13921 gaaggagatg ggcggcgtta tgttcatctg tgcggatcat ggaaacgctg aggtcatggt
    13981 ggatccggag acaggaaaac catggactgc ccataccacc aatccagttc catttatcct
    14041 tgtaggagca gacgcttcct acggactgag agaaggcgga tgcctggcag atatcgctcc
    14101 gactttaatt gaactgatgg gtatggagca gccgaaagag atgacaggaa aatctcttct
    14161 gattagaaaa taggaaagca gggagaatgc gggaggagaa ggaatgaaaa cagcgattgt
    14221 cacggacagc aacagcggaa ttacccagaa gcagggagaa gaactgggaa tctacgtgct
    14281 tccgatgccg tttatggtgg acggcagaac gtatctggag ggagtggacc tgactcatca
    14341 ggaattttac gagaagatga acggaggcgc tgatatcagc acctcccagc cttctcctga
    14401 ttcagtgatg aagctgtggg acggacttct cacaacatac gacgagattg tccacattcc
    14461 catgtccagc ggcctttcca gcgcctgcca gacggccatg gttctggccc aggactatga
    14521 gggaaaagtc catgtagtgg ataaccaccg tgtttctgtt actcagagac agtcggctct
    14581 ggacgccctg gaactggcga aggcaggggt aagcggcgct gatattaagc ggaagctgga
    14641 ggagacgcag ggagattctg tgatttatat tacagtggac acgctcaagt acctgaaaaa
    14701 gggagggcgc attacagctg ccgccgcagc cctgggcacc cttttaaaga ttaagccggt
    14761 gctgattatc ctggggaaaa agctggacgc cttttccaag gccagaacca caaaacaggc
    14821 gaaaaacatc atgatctcag cgatccagaa ggacttgaag gagcgtctgg gagatgaaac
    14881 ctgtacgaaa acgcatattg aaatcgccca cacgcagaac gacgaggcgg cccaggcttt
    14941 cagcgaggag ctgagagagc tgttcccgga ggcagatatt tatctggatc cgcttccgct
    15001 cagcattgcc tgccacatcg gcccaggatc cctggccctg gcggctacca ggaggatgga
    15061 agcatagatg tggggcggcg tttttaagaa aaagaccagg agggaggccc gccatgcagt
    15121 cagcatgcgg ctccctctgc ttttctgtat tctggtattt accattgttc cccttctcac
    15181 tcagtcagcc atgctgacct ccacgctgcg gcagagccag gtggaggata ccatgatcca
    15241 tgcccagaat aaatgcctga tcctggtcaa caagatgctc agttccgact atgcgaacag
    15301 cggggcgaaa aatccgatta tggatacaga gttggcagtg acggcagagc tgtttaacgg
    15361 ccggattctt gtggcagacc ggaattttaa gattgtgaag gatacctacg ggctggcaga
    15421 ggggaaattt aatatcacag aggaagtgct gaaggcctat tctggagaga cgcagagcag
    15481 ctacaacaga aaaaaggact atttttccct ggcgtttcct atccaggaga aggagaaaaa
    15541 cgggacggca gacggagttc tgttgtttac tgcgtccaca gagaggatcg agcttctgga
    15601 cagccagatt tctgagaaaa tgttcttttt tcagattgtg attctctggc tggccgccgg
    15661 tctggcattt ttagctgccg gcgtgctgat ccggccgttt acaaggcttc ggaaggttct
    15721 gggaattgtg gcggacggag atctggaaca ggatatcatg gtcggtgact ataaggaaac
    15781 cagggaaatt tccgatgcgg tgagccgcac gctggggaaa ctgaaagcgg tagaccagtc
    15841 caggcaggag ttcgtctcta acgtatccca tgagctgaaa acccctatca cttctatccg
    15901 ggttctggcg gactctctga tgggaatgga ggatgccccg gcagagcttt accgggaatt
    15961 tttatccgat atttccgatg agattgaccg ggaaagcaag attatcgacg atctcctgac
    16021 gctggtgcgg gcagataaat ccaatgcgga gctgaatgtg gccacagcca atttaaacgg
    16081 ccttctggag cagattttaa agcggcttcg gcccattgcc aagaagagaa atatcgagct
    16141 ggtatttgaa agcatccgcc aggtgtctgc agatgtggac gaggtaaagc tttccctggc
    16201 cctcactaat ttagtggaaa acgccattaa gtataatcat gaggacggct gggttcatgt
    16261 gactctggac gcagatcaca agtttttcta tgtaaaaatt tcagacaatg gaattggcat
    16321 atcccaggag gcgcaggagc acgtgttcga gcgtttttac cgggtagaca aggcccggtc
    16381 aagggagaca ggaggcactg gcctgggact tgccattaca aagagcattg tgctgatgca
    16441 ccagggagcg atcaagctgc agagcaggga gggggaggga accaccttca ccgtccggat
    16501 tcctctgaat tatattccgt agaggcggcc tgaaatgaga aaattcaaag agctttttta
    16561 cagacagaag ttcggaaaaa acaggagggc agaaatggaa acagcggaaa aaagaaccgg
    16621 gagaggaaag aaggcggcgt ttcttctggc ggcagcactg cttttagcag tgttctgcac
    16681 aggctgcaag ggaaagcaga aggaagaaaa cgaggcgtcc ggatcgggag agtaccagat
    16741 ttattacttg gacgcttccg gcctgaagct cagcccctgc agctataaga cagagacaga
    16801 ggacacggaa cagcttctcg gagaactggc cggccagctt ctgactcctc cggcagatac
    16861 ggagtaccag ccggcgttga cggataagac aaagcttctg ggaatgaaaa agaacgacaa
    16921 cgtactctat ctggatttca gcaaggagta caactccata gagccgatcc gggaaatcct
    16981 gtgccgggcg gcgtttgtca agacgctgac tcaggcggag ggagtggagt tcgtggcgat
    17041 cagctgcgag gggcagccaa agctggacag cgccggaaat ccggtgggag ctttgggaaa
    17101 gagcgatttt gtggagggag tcacggatat taattcctat gaacaggcag agctgaccct
    17161 ttatttttct aacgaggagg gaacggccct gattccggaa accagaactg tggtgcacag
    17221 cgccaacacc tctctggaac gtctggtggt ggaacagctg gtagcgggtc ctctggacga
    17281 cgcggtaaat cccgttcttc ccaaggagac caagatttta aacgtatctg tggcggagaa
    17341 tatctgctac gtaaactttg acagcagctt tctggcagga gtgccgaaca cctcggaaaa
    17401 actgacagtc tacgcaatcg tggattctct gacagagctt cagacagtaa ataaagtgca
    17461 gattacagta aacggatccc aggatatcat gtaccgggat gcaatccccc tgaatcagcc
    17521 atttgaccgg gacgagcagt atattttgaa tcaggaggga taagacaagg aggaaataat
    17581 cataaaacga ccgctacttt ggacagcagc agccattgta cttggagagg caggggcgta
    17641 tctggcctgg agaaatgcgg cggatgaaat catcgtaaaa ggcggcgcgg cagcatttgc
    17701 ggcggcgctg gtattctgtg ccctttttgc ggatactggc agaacagccg gatctgtaag
    17761 agggcttttt tcaatggaaa caggcttttt aaagtctgga acaggaagct ttgcagccgt
    17821 ctggattctg gcggcagcgg cccttctggg ggcggccagg atgggaggcg gactccagga
    17881 ggaaactatt gtaaaagaag agggaaatcc aggtttttcc gatctgacag ccagagcgga
    17941 gggcactgtg gaggcgattc aggagaagaa tggaagggta tctgtccagc tgaagcatgt
    18001 aaaaacagtg gtgagaaaaa cagatgaggt gaggcagcag gggaaaaggg agtacgctct
    18061 gaaacgtctc ctggtctacc ttccgccgga ggacatggaa atcggggaga tcctgccggg
    18121 agtgaagatt ctttgcacag gggaattaga aaggtttgaa ccggccagaa atgagggaga
    18181 gtttgattac cgcctttact accgttccag ggatatctgc tgcaggatga gcgcaaagaa
    18241 ggcagaaata acagaacatt ccgtctggct tctgcaggct gtgacataca ggattcgtga
    18301 acaggcgaag aagcttttag aacaatactg cacagagacg gacgcagggc ttctggcggc
    18361 agtcctcctg ggagacaaaa ccaggatgaa tgaggaaatc aatgagttgt atcagaaaaa
    18421 cggcattgcc caccttctgg cagtcagcgg gctccacatt tctttaatag gaatgggggt
    18481 atatcgtctg ctcaggcggc tgggactggg gtttggaacg gccggcttct gggtaggcgg
    18541 gctgcttttt gtctatggaa ccatgactgg cttcggaccg tcagtttttc gggcctgtct
    18601 gatgctcgcc tgttccttct gggccgctta tctgggcaga acttatgatc ttctatctgc
    18661 catggccctg gcagcagtct gtctgtccct cgaaaaccca tttgtcatct ttacaggggc
    18721 atttcagctg tcctttggag ctgtgtttgc cattggctgg gccggaacag agctggccga
    18781 caggctgaga tgccaaaaat cttgggagaa ggccctggcg gtaagcctgg cgattcagct
    18841 agtcactggc cccattgtac tgtatcattt ctttgaatat cctctatacg ggattttttt
    18901 aaattttctt gtgattcccc ttatgactta tgtggcagga gcgggaatgg caggtcttct
    18961 catggggatg gcaggcgttt ttgccgtctc ttttattcca ggaccgacgg cgcttttttt
    19021 gaaaaagatg ctggacattg gagctgtggg aagcatggga acatgccact acattttcat
    19081 ggtatatgag atgctctgcc gtgcagcaga gaaactgccg tgcagttccc tgatcctggg
    19141 gagaccgaag ctttggaagt tagctgccta ttatgctgcg ctggctgtgt ttcttgcctg
    19201 tgcagggagc cggggaagaa ggtgggaagc agagaaagag ggacaagagg agaaagcaga
    19261 gagaaagggg aaagaacata taaaaacctg ggggattctg ttcgcactcc ttgcttttct
    19321 cctgcaccgc tctgtttccg gcctcagagt cgattttatt gacgtgggac agggagatgg
    19381 tattcttctg gagacaagag agcaggtgat tttagtggat ggaggcagca cccagatcaa
    19441 aaagctgggg gaacagcggc tggaaccact gctaaagagc cgaggaatca gaaacatcga
    19501 tatggtattt gtcagccatg gagatcagga tcacatcagc ggcattacat ggcttctgga
    19561 ggaggacaca ggaattgaaa tcggccgcct gtttcttcct tttccgggaa agggggagga
    19621 ggtctatgaa aggctggagt ctacggcaga gaaaagagga gtaaaaacag actatatctg
    19681 cgccggggac tttgtccagt cagggaaact ttccctgtcc tgcctgtacc cttacagaga
    19741 caccttaagc agcgacagaa atgatcattc agaggtgctt ctggcagaat acggcgattt
    19801 ttccatgctt ctcatggggg atctgggagc agaaggggag gcagagattg cagagcagtg
    19861 gaataaaaac aggcaggttc agattttgaa ggcagggcac cacggttcct ctacctccag
    19921 ctcagaacag tttctggaca cagtacaccc aaggatagct gttctgtctt atggaaagga
    19981 taattcctat ggccatcccc acccagaggt catcgaaaga tttgatgaaa ggggcattgc
    20041 ccggtgggcc acagaagaac aggggatgat taccatccgg acagatggag aagagatgga
    20101 gattcaggga tttatccaaa acaggtagaa cagcagtttt tgtctaatta agcgcacact
    20161 gctgttaata gcactgttga agtatctgtg cgactgctgt gtatagatgc agaaatcaga
    20221 ttggcaaaca gggagattga ttatataata gtaccggacg gtaagattac agtaaaacag
    20281 aaactgcagc gtgtaagcag tgaacggaga aacggatatg gagacattaa atcaggatat
    20341 caagtcggga aatttcaagc gtttttatct gctgttcgga gaggaagaat ttctgaagca
    20401 aagctataaa aagcgtctcc gccaggctgt ggcaggaaac gataccatga attacaatta
    20461 tttcgaaggg aaagggctgg acgtgagaga gctgatcagc ctggctaata ccatgccttt
    20521 tttcagcgac agacgtctga ttatggtaga ggacagcgga ttttttaagg cagtctcgga
    20581 cgagctggtg gaggctcttc cggacatacc ggataccacc tgtatagtat ttgcagagtc
    20641 agcggtagat aagagaaacc gcttatataa gaaggttaag gaactgggaa gcgccgtaga
    20701 actgaagcgg cagagcgcct cccagctggc tgtctgggca ggcaggatcc tggcacagaa
    20761 cggaagaaaa atcacgtctg ctgatatgaa tttctttctg gaacggacag gagacgatat
    20821 ggaaaccatc cgcacagagc tggaaaaact gatttcctat actatggggc aggaagtggt
    20881 gaccagggag gacatagagg cagtcaccac tgtgcaggtg acaaataaga tctttgacat
    20941 ggtgacagct attgtgacag gaaagacgaa aacagccatg gatctgtacg aggatttgct
    21001 gacattgaaa gagcctccta tgagaatcct ctttttaatc gccagacagt ttaaccagat
    21061 tctgctggtg aaagagatga tggcgtctgg aaatgataaa agcgccattg cttcaaagct
    21121 gaaaattccg ccttttgtgg ccggaaaact gatgccccag gccaggactt ttacaagaga
    21181 gcagctagcc ggctgcgtgg aggcttgcgt ggaggctgag gaggcagtca agacaggcca
    21241 gctgggagac aggctggcgg tagaactgat gattatgagg aagtactagg aggccaggct
    21301 gaggaaggcg tcctgaagtt tagccagggg gaactatgtt tacagagagt gatatcagaa
    21361 aacagacgga cagaggaatt acctatataa agggatataa gctgtataca aacggcagcg
    21421 tgctgggact ggatgaagaa tacagcgagg aggacagatc ctgctttgta gcaggaagcg
    21481 tagagggaag ctatggtaat gagtacgatg tcagtatcgc actggatgac aatgaggaaa
    21541 ttaaaagcta ctcctgtacc tgctctgcat ttgagactta tcctggaatg tgcaagcact
    21601 gcgtggctct ggccctggaa tatctgtatt cccgggaaga tccggaaaga gaagaagagt
    21661 ttgaagataa tccgctgggt ttcaggaaaa accgtacaga tacggagata ctggatgttg
    21721 tagcggcttt ttctctgcgc aggcggatga aggagcagac tgcctgcgga aagattgaaa
    21781 tcataccgga actgcaggaa atttccagat attgctatta tggaaacaga ggaaatttta
    21841 agctgacctt taaaattggc ctggaagacg ggaaacagta tgtgctgaaa aatgtcagcg
    21901 attttctggg gcatatatac agggaagaaa tgcattccta tggaaagcag ctggcatttg
    21961 tccatagtaa aaacgcattt acagagacag cctggaagta catagagctg atggagcagg
    22021 cgagacgaga gagtagcgct cgctatgagg agctgggaag agagatcatt ctgacgccaa
    22081 aactgtggga tgcgtttttt gagattaatc aggggagctc gatggaatac attgcaatta
    22141 ccagacataa aagggaactg cattttttga aacaggagcc tccggtcagg ttcaggctga
    22201 tcgcagaaga ggagaaagga ttccagataa aaattcctcc gctgcagtta atcagaggag
    22261 gggacaggcc gtatgtaaag cttcagcaga gcatttatca gtgttccgat gatttttatg
    22321 ctggagcagg ggaatttttg aagctggcag atgaaaaaaa ggagacatcg taccatatcg
    22381 ctaggaagga tatgcctgcg ttctgcgggg cggtgcttcc tgaactggat gaattgggaa
    22441 ttgcagacag ggggaaactg gatttgggag agtttcagcc taagaaggca gagatttcct
    22501 tttatctgga tgaggaaaac gggcgggtta cgctgaagac tatgggaatc tatggagacg
    22561 cggcttacaa cctgctgaaa ccaacagatt tttccggtga ataccgggat cgcaccaaag
    22621 agatacgggt gcagaacctg atccgatcct atttttccct ggaagatatc ggggagggaa
    22681 tcctgtactt tgaatccgac gaccatgaca ggatgtacca tctgctgaat tcaggaatca
    22741 gccagtttga ggcggaggga acagtctatg ccacagacag aataaaagga cgaaaattgc
    22801 tgaagaatcc cagaacacag gtgggagtgg cgattaaaag cggtcttctg gagctgtcgg
    22861 tgcagagcag tgagtttctg cctgaggagc tggcaggcat actggacagc taccggaaaa
    22921 aggagaaata ccatcttctg aaaagcggaa gttatattgg actggaagaa aattctgtgg
    22981 ctacagtagc ggagctgtta gacgggctgg gtgtatcagg aaaagatttt gacgaaggca
    23041 ggctggagat tcccagattc agagcctgct atgtagatca gatgctcagc cagaaggagg
    23101 gacagcttca ggcagagcgt agctctgact ataaagcagt gattcgaaat atgaagaacg
    23161 tggaggacag cgattaccag actcctgaga cactgcgaga cgtactcaga gagtatcaga
    23221 agttcggatt tcggtggctg aacacgctgg cagatctggg ttttggagga attctggcag
    23281 acgatatggg gcttgggaaa acgctgcaga ccattgccta tctgctgtat cggaaacagc
    23341 agagaaagac ggaatgtcct catctgatta tctgccctgc ttccctggtc tataactggg
    23401 agagggagat agaacggttt gcaccagagc ttaaaacagc agttattgcg ggaaatgcac
    23461 agcagagaga agagatgata aagggagacc agaaggctga tatctggatt acctcctacg
    23521 atatggtaaa acgggacatt tctctgtata aggaacgtca gtttgataca gaggtgatag
    23581 acgaggccca gaatattaag aatcacggca ctctggcagc aaaagcagtg aaaaaaatcc
    23641 gtgcagaggt gcggtttgcc ctgacaggta cgcctattga gaacagactc agcgaactgt
    23701 ggagtatttt tgacttcctg atgccgggaa ttttgggaac ttacgagaaa ttccgaaagg
    23761 gctatgagct tcccattgtg cagaaccagg acgaacgcct ggcaaagcgg ttgaaaagga
    23821 tgatttctcc tttcattctg cgcagggtaa agagcgaggt tttaaaagaa cttcctgaca
    23881 agctggaaca ggttgtatat gcccggatgg gagaagaaca gaggaaaatt tacgagtccc
    23941 atgcccttcg tctgatggag agcctcgaaa aacaaagcga ggaagatctt caaaaaggaa
    24001 agcttcagat actggcagag ctgaccaggc tgcgccagat ctgctgtgct cctgagatgt
    24061 tgtatgaaaa ttatggagag atttcatgca aggtggagac atgcatggag ctgattcatc
    24121 aggcgatgtc aggaaatcat aaagttctgc ttttttccca gtttacaagt gtatttccca
    24181 ttttagagaa acgtctgatg caggaaaaaa ttccttacta tgagctgaca ggccagacct
    24241 ccaaggaaaa acgaatgcag ctgacagaac agtttaattc cggagacgtg ccgatattcc
    24301 tgatttcttt aaaagcagga gggacaggat tgaatctgac ggctgccagt attgtcatcc
    24361 atttcgaccc ctggtggaat ctggcggctc aaaatcaggc tacagaccgg gctcaccgga
    24421 ttgggcagga gcagcaggta actgtattta agctgattgc acagaataca atcgaggaaa
    24481 aaatcgttaa gcttcagcag gagaaggaaa agctggccag ccagatatta gatggggaag
    24541 gtatggcagt ctctgccctg acgaagaatg attttatgga aattctggaa ttttagtaat
    24601 ttcagcaatt attttaaata catatttata tacgttaaat caaataggat agaatggaaa
    24661 agtgtcgctt aacagattat taagcgacac ttttttttaa tgggttataa aaatcttttt
    24721 cactgtcaga acaaaaattt tgttcccgta aattataaca ccctttacag ggggagtcaa
    24781 tcgccacaga caggtacata tttcatatat ttctaaaaat ttcttagttt tctttaaata
    24841 ttcatctcag aaaaactcaa aataaccagc tatgtttcag aaaagggaac aacatgcaaa
    24901 atctattttt tgtcagcgct taaaaagtgt cgcttaataa tctgttaagc gacacaaaca
    24961 gaaaggatga gtacagatga gctggtatgt actgcagtgc cgtgcgggaa gagaggcgga
    25021 aatggtcaat tccctgaacc agcatttgtc cagagaggcg ctggaggaag cattctattt
    25081 ccagagtgaa cggctttgga ggtcagaagg cagctggaaa cgtcagaaaa aagaactgtt
    25141 tccagggtat gtctttcttc agagtgaaaa tcccggactg ctgtcagagg cattggagga
    25201 ataccgccag atcgtccgga tcatggaaga accgggatat ctgatttctg tctatccgga
    25261 agaagaggaa tatcttcggg gattatgcgg gacagatcac tttctgccct tgtcctacgg
    25321 ctataaggat cgggtgacgg gatgttccag aatcacaaag ggaccattag ctggacggga
    25381 gaatcaggta aaaatctttg actggcacag gcgctttgcc aggatggaga tttccatcga
    25441 aaacaggaag gcgtctgtct gggccgggct ggctcttgac gaggcggcag tgtcgtaggg
    25501 aactctgcga actactggga gggaggtcag gaaaactgac tttctaaaga gattggatga
    25561 aaaattccgg aatatgcagt acagcttatg aggcatgctg ggttgaacgg atgtgataca
    25621 ggcgtcaaaa cgcagacaga aaatcagggt aaacgctgaa tttttttcag ctgattatgc
    25681 tggtatggcg aagctatacc tttttctgcc gtgaaaggcg cttgcaggaa ggcggaaagc
    25741 acctatgtgg tatgtaattc agacagagac cgggagagag gaagaggttc tttccctgat
    25801 gcgtcggctg ctggataaaa ggctgtgcag caggtacatg attctggagg cagagtggcc
    25861 gaagcgatcc ggcggacagt ggctgcttct gcgaaaagcc atgtttcccg gatatatctt
    25921 tgtggagaca gaggaagcgg aggaagtgtt ctttcagctg aagcagattc caaagctgac
    25981 aaagatcctt ggaaatgaga aatttgagtt tgttcctctg gcagaggaag aaattcagtt
    26041 tctgtataag atttccaaga cagcagagaa aaacgggaca gaacagcggc ttctggtgta
    26101 tccaagcaga attactgtgg ataaagcagg aaccattaac gtaataagtg gaccgctgaa
    26161 ggaatttgag aaagagattc taagggtcaa tcttcataaa cggtacgcag tggtaaaggt
    26221 gaaaatgctg ggagaaaaga cggtactgtt tgggatagtg atggagaagg acagggagag
    26281 aagaagttag aaagctagat gaaatattaa aatagagata gaaaagataa gaagaatcaa
    26341 tagaaaaagc ctgtgaaggg ctttttttga tcacggaaaa tgctaaggag gagttcgtat
    26401 ggaaaagaaa cgtatttttt tagcaagtcc tactatgaac ggacatgaaa tggaatacat
    26461 tcaggaagcc tttgacacta actgggtagc tcccctggga aaaaatgtag atgaatttga
    26521 aaaagagctg gcagcttacg caggggtcag ccatgcggcg gcattgagcg ccgggacggc
    26581 ggctcttcac c
//
LOCUS       DBMDUW010000032        25981 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1305_length_25981_cov_3.212944, whole genome shotgun sequence.
ACCESSION   DBMDUW010000032 DBMDUW010000000
VERSION     DBMDUW010000032.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 25981)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 25981)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25981
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1305_length_25981_cov_3.212944"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..396)
                     /locus_tag="ACZPCR_07395"
     CDS             complement(<1..396)
                     /locus_tag="ACZPCR_07395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1230737.1"
                     /translation="MSRKRGEEYRRMKGKDRKIGLTSSGIMTILVVSMVFFSLLAGIV
                     VFVTTYRASMIQNVKTSSDQAAVQVERIVDNYMDDISSSLKLIEGFFLEEDPVRDVNL
                     NHMADIRSDVTAITSYDPETGELTGAWTGH"
     gene            complement(393..1997)
                     /locus_tag="ACZPCR_07400"
     CDS             complement(393..1997)
                     /locus_tag="ACZPCR_07400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016289989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIR1230738.1"
                     /translation="MYTIVVADDEEELRRAIIRRINWEEIGFQVVGEAENGVEALEMV
                     SEKEPDLLLTDIRMPFISGVELARQVREIRPATQIAFLSGFDDFSYAQQAIQYNIISY
                     MLKPISMADLTENLIQIKQKIDHLFSEFAQRRKNELGISEFLLPLLLDSFQTNFSPER
                     EERLCSQARACGMIRPESENIRYLVISVTFWDEKGANCTDHSHVHSVDSILKKYIKYE
                     SFFLEDRIVSVLWATPASFDKYLHILADDIVQSTDRILNLKCSVGASRVLNGFTELSE
                     GYRDAVNAMRYASRSKTGGVRYITDEEPFSGVDMDYVMKVVASIEEKIRGGSREELEE
                     YLWEVFGHLRDENNSREKVNFMLVEILSCVCRIMYSVSAESDAAALKSDPFMQQMVFL
                     DSSLKDAADHFVNFCMTARDRISEQKTKSSMDICDKAIRHIEDNYFKADLSLMSASTE
                     IGVSPNYLSSLIKKRTGKSFVDYLTQKRMEAAKTLLLNTAMKIKEVSETCGYNDQHYF
                     SYCFKKYEGVSPNMLRRRLSQEETQA"
     gene            2189..3649
                     /locus_tag="ACZPCR_07405"
     CDS             2189..3649
                     /locus_tag="ACZPCR_07405"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007713829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD+ biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HIR1230739.1"
                     /translation="MEPRNLTLLTDLYELTMMQGYFHEKDANETVIFDAFYRSNPDGN
                     GFAVCAGLEQVIEYIKNLHFSEADIKYLRSVGLFTEDFLDYLRNFKFTGDIYAIPEGT
                     VMFPREPIVKVIAPIMQAQLVETAILNIINHQSLIATKTSRVVQAAQGDGIMEFGLRR
                     AQGPDAGIYGARAAMIGGCVGTSNVLAGQMFDVPVKGTHAHSWIMSFPDELTAFRTYA
                     KLYPTACILLVDTYDTLNSGIPNAIRVFTEMREAGIPLKGYGIRLDSGDLAYLSKKAK
                     AMLDAAGFTDAIISASNDLDEYLIDSLKIQGAAINSWGVGTNLITSKDCPSFGGVYKL
                     AAILDRETGKFIPKIKLSENTEKVTNPGNKTIYRIYDRANHKIIADLICLADEVYDEN
                     KSLLLFDPIETWKKTHLSPGSYEMRELLVPVFKDGVCVYQSPKVMEIRDYCRRELDTL
                     WDESRRLINPHEVHVDLSNELWHMKNQLLDSYHYNR"
     gene            complement(3932..4660)
                     /locus_tag="ACZPCR_07410"
     CDS             complement(3932..4660)
                     /locus_tag="ACZPCR_07410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013272278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HIR1230740.1"
                     /translation="MSGHSKFANIKHKKEKNDAAKGKIFTVIGREIAVAVKEGGADPA
                     NNSRLRDVIAKAKANNMPNDTIDRGIKKAAGDANSVNYEELTYEGYGPNGVAVIVTAL
                     TDNKNRTAANVRSAFTKGGGNIGTQGSVSFMFDKKGQIIIDKEECELDADTLMMEALD
                     AGAEDFAEEEDSYEILTSPEDFSAVREALEAKNIPMMEAEVTMIPQTWVELTDDESIK
                     KMNRLLDLLEDDDDVQATYHNWDE"
     gene            complement(4793..6175)
                     /locus_tag="ACZPCR_07415"
     CDS             complement(4793..6175)
                     /locus_tag="ACZPCR_07415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007864114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1230741.1"
                     /translation="MEKGIFYDVKMMARDGIFLKKAVRIALPVAMQGMLNTIVNLVDT
                     MMIGSLGATAIAAVGLANKVFFVFTLLVFGIVSGSGVLAAQYWGNGDIKNIKKVVGLA
                     LSLAVAASIAFLVPAVVCPEAVMRIFTASEDAIQVGAGYLTIVALSYPATAVSNTFVA
                     MLRATGRVKAPVVISSCTIFINIFFNYTFIYGNFGAPAMGAAGAALATLMARLVEALS
                     IILVVYLGKAPVAAKFKEMFGYSREFLVQFFSTTSPVIANEFIWGLGTTLYSLAYGRM
                     GNDAVAAITIATTIQDIVTVLFQGLSAATAVIMGNEMGAGKLKRAERYAKNFLILQFI
                     VTILGALFCVAIRWQIIGVYNITPEIAESVSRCIIVFALFMPFKMFNYVMVVGILRSG
                     GDTKMCLLLDCSGVWMIGVPMAFLGGLFFGFPIHIVYAMVMLEEVYKAVFGYWRYRQK
                     KWLRNLAAEL"
     gene            complement(6197..7558)
                     /locus_tag="ACZPCR_07420"
     CDS             complement(6197..7558)
                     /locus_tag="ACZPCR_07420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HIR1230742.1"
                     /translation="MDDGYWPLSIVIFAAFILLDAVLYGFGAAIQHLNSGTLEKEAQE
                     GNKKAERLLAVISQPAEFIGTVQIVTNLIGLVSGAMILKEAGALLGLLIHRTGETGEG
                     FSLIAATAAAAVMLLAALISLGIVVPKRCASKHPEQWAYRYVGVSSVIVALFKPFAWL
                     VSGLSWLILKPLGIGLHDKNDSVTEEDIMLMVNEGHEQGVLEAGEAEMITNIVELGDK
                     DAGDIMTRRKQIVALDVSMTLKEAVAYILTEGSNSRFPVYDEDIDDIKGILHLRDTLS
                     CAQKEENLDKRLDEVEGLLRTPHFIPETRNINLLFKEMQSQKIHMEIVVDEYGQTAGI
                     VTMEDILEEIVGNILDEYDEDEELISRKADGSLIFDGLTPLEDVGKELEIEFEEEDYE
                     NFDTLNGFLISRLNRVPREGETPEVTYKSYLFQVISVENKVIHTVRAVRSRGEIEKPG
                     EDS"
     gene            complement(7718..8059)
                     /locus_tag="ACZPCR_07425"
     CDS             complement(7718..8059)
                     /locus_tag="ACZPCR_07425"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA];
                     GO_process: GO:0016075 - rRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HIR1230743.1"
                     /translation="MVIKRGDIYYADLRPVVGSEQGGVRPVLIIQNDIGNKHSPTVIC
                     AAITSKMNKAKLPTHVELDTRRCGMVRDSVILLEQLRTIDKQRLRERICHIDEELLGR
                     VNQALMVSLEL"
     gene            complement(8160..9377)
                     /gene="alr"
                     /locus_tag="ACZPCR_07430"
     CDS             complement(8160..9377)
                     /gene="alr"
                     /locus_tag="ACZPCR_07430"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015542823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HIR1230744.1"
                     /translation="MWKKEENVTAGREHDFDRICVLVHLDRIRQNMKSMKENLPEGTK
                     IIGVVKADGYGCGAGETARAADPYAAAFAAATADEALSLRREGILKPVLVLGSVPKER
                     FYELLAADIRPVIFEEEMAAAFSEIASQAGILGKIHLAVDTGMSRIGFQPGEQALEEI
                     RRISQMKGIEIEGMFTHFARADELDKQWAERQFQKFRDFSAAVSQLLEKAEPGRKKLF
                     CHCLNSAGIVDFHRMPKGSEMNGARAGIAMYGLYPSGEVDHSRVRLLPVMEFKSRITY
                     IKEIPSGTAVSYGGTFTADRPMRIATVSAGYADGYPRGASGKGEVLIRGKRARILGRV
                     CMDQLMADVTDIPEAEKWDEVTLVGRDGQEEITMEELADVSGGFHYELPCLIGKRVPR
                     IYTWGNQGQNTLI"
     gene            complement(9353..10900)
                     /locus_tag="ACZPCR_07435"
     CDS             complement(9353..10900)
                     /locus_tag="ACZPCR_07435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HIR1230745.1"
                     /translation="MRQLVTGEQMKAVDQYAIQEVGIPSLVLMERAALSVVEEMEPEL
                     FREDQILIACGTGNNGADGAAVGRMLFLRGYHVTVVTVGREESRTEELKLQLSINEKL
                     GLSAMEAEDFIPGTCQAAVDALFGVGLSRNVEGAYRDMIETIEDMKPRLTVAVDIPSG
                     IHSDTGKVMGTAVKADLTVTFGFKKVGLSLFPGREYSGRVVVKDIGFPPCPAERLTGR
                     RYVTCGPEDLELLPGRKPWSNKGTYGHVLIAAGSPGMAGAAYLSALAAYRMGAGLVKI
                     LTPAENREILQTLIPEAVLSVYDCAEALEEPEQFLGKIEKECGWADAVVLGPGLGKEP
                     WAVRLVQQVLLSAFVPIVLDADGLNIVAENPSLSEYFTENVLVTPHVGEMARLSGLEI
                     EEIQADLTKAAEDYSEKYGVIIVLKDAATVVVRKDEPIYINSSGCAAMAKAGSGDVLT
                     GVLAALIAMGMEEGQAAVLGVYLHGLAGEAAEKALGENGVLARDLADSLADVEREEAV
                     CGRKKRT"
     gene            complement(10919..11287)
                     /gene="acpS"
                     /locus_tag="ACZPCR_07440"
     CDS             complement(10919..11287)
                     /gene="acpS"
                     /locus_tag="ACZPCR_07440"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009533692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HIR1230746.1"
                     /translation="MIAGVGTDMIEIARIKRACEKKAFLTRVYTQEECQQAGENYSRL
                     AGTFAVKEAVSKALGTGFRSFGPREIEVLRDDLGKPFVRLHGGAKKLAEELAIQQIHV
                     SITNTAEYAAAFAVGERADQ"
     gene            complement(11284..11961)
                     /locus_tag="ACZPCR_07445"
     CDS             complement(11284..11961)
                     /locus_tag="ACZPCR_07445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002600292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HIR1230747.1"
                     /translation="MEQKEISKAVISRLPRYYRYLGELLEEGVERISSNELSVRMKVT
                     ASQIRQDLNNFGGFGQQGYGYNVKYLYSEIARILGIDRQHNLIIIGAGNLGQAIANYT
                     NFERRGFLIKGMFDVNPRLVGLVVRGVEIRGIEDLEQFIKDNDVQIAALTIPKSKAPE
                     IADRLVKAGIKAIWNFAHTDLVVPDDVVVENVHLSESLMRLSYRVCSMQDQKEREKSQ
                     AKGKEAK"
     gene            12166..14181
                     /gene="abc-f"
                     /locus_tag="ACZPCR_07450"
     CDS             12166..14181
                     /gene="abc-f"
                     /locus_tag="ACZPCR_07450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006772083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="HIR1230748.1"
                     /translation="MILSCSNISKSFGTDSILNHVSFHIEEREKAAVVGINGAGKSTL
                     LKIIVGELAPDEGSVVIAKGKTLGYLAQHQDLDSGQTIYDELLEVKRPIIEMEERLRT
                     LEVNMKRSQGEELESLYQTYSRLSHEFELANGYAWKSEITGVLKGLGFLEEEFSKPVS
                     TLSGGQKTRVSLGKLLLSKPDIILLDEPTNHLDMESIAWLENYLLNYQGTVVIVAHDR
                     YFLDRVVTKVVELDNGSSTVFQGNYSAYSEKKAMLRASILKAYLNQQQEIKHQEEVIT
                     KLRSFNREKSIKRAESREKLLNKIERIEKPTEVNDAMNITLEPDIVSGNDVLTVLGLT
                     KGFDGQTLFSDVDFEIKRGERIAIIGNNGTGKTTILKIINGILAADAGEIRLGSRVHI
                     GYYDQEHHVLHSEKTLFQELSDTYPNMNNTQIRNVLAAFLFTGDDVFKLIGDLSGGEK
                     GRVSLAKLMLSEANFLILDEPTNHLDITSKEILENALTHYTGTVLYVSHDRYFINKTA
                     TRILDLTHNTLVNYIGNYDYYLEKRDTMEQLFSASPAASSKPSENNSQAAALAASGPV
                     NAASLPWSGDRGNASSSDSGDSSGKTDWKQQKEEQARLRKRQNELKKTEDAIHQLETR
                     DGEIDSLLCQEDVFSDVAKLMELNAEKQSIAGQLEELYEKWEELAED"
     gene            complement(14198..15199)
                     /locus_tag="ACZPCR_07455"
     CDS             complement(14198..15199)
                     /locus_tag="ACZPCR_07455"
                     /inference="COORDINATES: protein motif:HMM:NF023166.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HIR1230749.1"
                     /translation="MKPEDGKGIYDSIEIPEELDQIVRQSIAEAEKRRREKEAEEKES
                     DKDRGGNVPEKSQEKRSAQAIRFSQRMAARFTAAAAGAAVVFTIGLNTNQAFAETMKQ
                     IPGIGFLAEVLTIRSYHQADQDYNIDAEIPAIVETGGPDGSGSQSGTAKSVNEQIEQI
                     VDNYLAEGKKEFAAYKEAFFAAGGTEEEWADRQMDLSVDYQVKYQSEEVLSLELITFK
                     GWVNAMEERYYYNLDLKQDRLLALKDVLGSGYVERCNKEVVRQIEARMAADENQMFFG
                     FEPNDDGMAEGFTTVDETTQFYINENQEVVLVFPEYSIAPGYMGITEFNMGKAEFPS"
     gene            complement(15196..15687)
                     /locus_tag="ACZPCR_07460"
     CDS             complement(15196..15687)
                     /locus_tag="ACZPCR_07460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006778919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1230750.1"
                     /translation="MEQNLYDSVAAYIIENQNRFYRLAYSYVGDREAALDVVQNAILK
                     GLEKCDTLRNQDAVKTWFYRIVVNEALQILRARKREELSADGEVFEQAYTEPAYDRER
                     EVYEAVRNLPDPGRTVVILHYYEDLTLKQIAEITDVNLNTVKYRLYSSLERLKKRLKE
                     EAL"
     gene            complement(15807..16967)
                     /locus_tag="ACZPCR_07465"
     CDS             complement(15807..16967)
                     /locus_tag="ACZPCR_07465"
                     /inference="COORDINATES: protein motif:HMM:NF040203.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HIR1230751.1"
                     /translation="MAAAAGAVCLMAAVFPCSALGAQAGEQVLQQENSEYSIPGTWTG
                     DDMDSRYLLEDGTCLEKSWLLWDGRWYYLDEDGYPAAGWNKIKGKWYYFNEDTGRMAT
                     GWLYSHEDGEWYYLNEDGTRKTGWLNTGGVWYWLDSNGVLYDDGWRMVDGHKYYFHSN
                     GQLAAGQYIGTSYYGSDGLRNPDYDMNIQGKRKPSDEEKEAVTKALENIPRQWMDRFL
                     AEGWEFMYYTDRRYMEAPMTDEGVCYVYHKTDQRYKKIKFTDPESLTRAFGEYAAGAV
                     EAGQEQKEKAEELYAVSGEISSGASLPDYFKDDYESWFGVLFENYCNPEIRSEMQMTA
                     PELCAAFDEMLGVDFTGLRPSVWDMTEEGEMDAGGAFGPALDPELNPILKGR"
     gene            17106..17315
                     /locus_tag="ACZPCR_07470"
     CDS             17106..17315
                     /locus_tag="ACZPCR_07470"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230752.1"
                     /translation="MNIRRILALAGVFLILLLYGASLVLGIIGSPKALDLLLAALFCT
                     MVVPAMIYGCGVLLKNSGRSGKDSR"
     gene            complement(17439..18716)
                     /locus_tag="ACZPCR_07475"
     CDS             complement(17439..18716)
                     /locus_tag="ACZPCR_07475"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HIR1230753.1"
                     /translation="MVRAIVGANWGDEGKGKITDMLAKESDIIIRFQGGSNAGHTIIN
                     NYGRFALHLLPSGVFYDHTTSIIGNGVALNIPFLFNEIEDIKKKGVPQPKILVSDRAQ
                     ILMPYHVLFDEYEEERLGGKSFGSTKSGIAPFYSDKYAKIGFQVSELFDEEYLYDKIK
                     RVCETKNVLLEHLYHKPLLNPDELFAEMKEYRRMVEPYVCDVSAFLHEAIKEGKNILL
                     EGQLGSLKDPDHGIYPMVTSSSTLAAYGAIGAGIPPYEIKNITTVVKAYSSAVGAGAF
                     VSELFGEEADELRRRGGDKGEFGATTGRPRRVGWFDAVATRYGCRIQGTTEAVLTVVD
                     VLGYLDELKICVGYEIDGKVTADFPTTRQLEKAKPVYKTLPGWKSDIRGIKNYEDLPE
                     NCRAYIETIEKEIQVPITMVSNGPGRDEIIVRK"
     gene            complement(18866..19789)
                     /locus_tag="ACZPCR_07480"
     CDS             complement(18866..19789)
                     /locus_tag="ACZPCR_07480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007711858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HIR1230754.1"
                     /translation="MNISLEYYKVFYQAAATGSITMAAETLCISQPAVSQAVKHLERE
                     LETKLFLRTPKGVRLTREGELLYGYVKRGIESIRDGEEMLKQLKCLDTGVIRIGASDM
                     TLQFYLLPYLEQFHEQYPKIKVMVSNGPTPETIEALENGAIDFGIVSTPFEGREEMRA
                     VPVRQIENIFIAGSRFREQLEGRELDYRELKDYPCIFLEKKTSTRRFMDQYLEKEGVA
                     LEPEFELATSDMIVQFVKRNLGIGCLMSEFAREALEREDVFELKFRHAMEKRSFCLIT
                     SLKNPLSPAAKKLLETLSPGGQDSKADRTEI"
     gene            complement(19939..21369)
                     /gene="purB"
                     /locus_tag="ACZPCR_07485"
     CDS             complement(19939..21369)
                     /gene="purB"
                     /locus_tag="ACZPCR_07485"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HIR1230755.1"
                     /translation="MHDRYVSPLSERYASREMQYIFSPEKKFCTWRRLWVALAEAENE
                     LGLPVTKEQIDELKEHMDDINFDVAKEREKLVRHDVMSHVYAYGVQCPKAKGIIHLGA
                     TSCYVGDNTDIIIMADALKLVRKKLINVMDELAKFADRYKAQPTLAFTHFQPAQPTTV
                     GKRATLWLMELKLDLDDLDYLLGSLRLLGSKGTTGTQASFLELFDGDHEKCRELDRKI
                     AQKMGFEGCYPVSGQTYSRKVDSRVLSVLAGIAQSAHKFSNDIRLLQHLKEVEEPFEK
                     NQIGSSAMAYKRNPMRSERMASLANYVMADMMNPMMVASTQWFERTLDDSANKRLSIP
                     EGFLAIDGILDLYLNVVDGLVVYPKVIEKRLMSELPFMATENIMMDAVKAGGDRQELH
                     EKIRTLSMEAGRNVKEKGLDNNLLELIAADPAFNLTLDELKKTMDPSRYTGRAKEQVE
                     EFLNEVIRPVLEENKEILGVKAEINV"
     gene            complement(21530..21862)
                     /locus_tag="ACZPCR_07490"
     CDS             complement(21530..21862)
                     /locus_tag="ACZPCR_07490"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230756.1"
                     /translation="MKNRKIRGRAGNGNESGLRRIRRRYMRRRLGKRARTRRLAFLCC
                     AALAAGYLLILADWGGRLFEIEEIQETEAPKKDGQSSQDEAEGKRKFGIIFRLKDGEI
                     TFYSESSY"
     gene            complement(22054..22413)
                     /locus_tag="ACZPCR_07495"
     CDS             complement(22054..22413)
                     /locus_tag="ACZPCR_07495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230757.1"
                     /translation="MKKCKQVLTAMCLAFVFVFLTACGSKEDVKNTTNASRVPETAET
                     SASRPSDGSMPGAEKDGMEKDRDFEESTGVLEGIGDDLKDGAEDTADWIEEGVTRAEE
                     GLEERDPDTEQNNQSDR"
     gene            complement(22504..23259)
                     /gene="dapB"
                     /locus_tag="ACZPCR_07500"
     CDS             complement(22504..23259)
                     /gene="dapB"
                     /locus_tag="ACZPCR_07500"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HIR1230758.1"
                     /translation="MVRAIMHGCSGAMGRVITDLVKDDKELVIAAGVDISEEGTCPYP
                     VYKSLDEVKEEADVIIDFSSAKATDGLLDYCARTGMAVVLCTTGLSKEQTQKAEEVSK
                     KAPVLRSANMSLGVNTLLKLLKEAAPVLYPAGFDVEIVEKHHNKKIDAPSGTALALAD
                     AINESLDNTCHYKYDRFSERVPRDSKEIGIQSVRGGTIVGEHDVIFAGTDEVITFTHT
                     AYSKAIFAKGAIQAAKFLGGKPAGLYSMADVIG"
     gene            complement(23339..24223)
                     /gene="dapA"
                     /locus_tag="ACZPCR_07505"
     CDS             complement(23339..24223)
                     /gene="dapA"
                     /locus_tag="ACZPCR_07505"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HIR1230759.1"
                     /translation="MAIFEGAGVAIVTPFKENGEINYSKFEELVEEQIAGGTDSIVVC
                     GTTGESATMSHDEHIRAIQFVCNIVDKRIPVIAGTGSNYTDTSMYLSQAAEEAGADGI
                     LLVTPYYNKTSEKGLKVHFSDIAQAVKIPALLYNIPSRTGVNMSPETIVWLCKNVENI
                     VGVKEASGNFSDIAKIASLSNGWVDIYSGNDDQTVPMLSLGAKGVISVLSNIAPRKVH
                     DMCDLYFKGKVEESMKLQLQAIPLINALFCEVNPIPVKEAMNLLGKNVGGYRKPLVEM
                     EPEHRERLIQAMKNYGLL"
     regulatory      complement(24354..24529)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            complement(24558..25064)
                     /locus_tag="ACZPCR_07510"
     CDS             complement(24558..25064)
                     /locus_tag="ACZPCR_07510"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002600311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008817 - corrinoid adenosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="HIR1230760.1"
                     /translation="MEKGSVQVICGPGFGKTTMALGKGVVAVTKHKKVIMIQFLKGSL
                     SAEVSEGLKCLEPDMKVFRFEKQGDYFEKLSEEQKKEEKINIQNGLNFARKVLTTREC
                     DLLILDEILGILDQDILALDEFEHLLSLRDEEMSLILTGKNFPDELTGYVDAISKIEN
                     VEIDNPAE"
     gene            complement(25162..25809)
                     /locus_tag="ACZPCR_07515"
     CDS             complement(25162..25809)
                     /locus_tag="ACZPCR_07515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016279329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HIR1230761.1"
                     /translation="MSEKVIENNKVSVIGEVVSEFTFSHEVFGEGFYLVSLAASRLSD
                     QVDVIPLMVSERLLDVKQDYRGQTVEAIGQFRSYNCHEGVKNRLVLSVFVRELNFLEE
                     FTDCTKTNQIYLDGYICKEAIYRKTPLGREIADLLLAVNRPYGKSDYIPCIAWGRNAR
                     YASGFAVGSRVRVWGRVQSREYTKKLSETQCEKRVAYEVSVSKLECGPDQEDQAQ"
     gene            complement(25794..>25981)
                     /locus_tag="ACZPCR_07520"
     CDS             complement(25794..>25981)
                     /locus_tag="ACZPCR_07520"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230762.1"
                     /translation="FEGGGAGGAGGFGGFSSADFGDIFGDIFGDFFGTRHIHIILAAK
                     LNMKFELGRGEVQCQKK"
BASE COUNT         5982 a         7626 c         5546 g         6827 t
ORIGIN      
        1 gtgtcccgtc caggcccctg tcaactcccc tgtctccgga tcatagctgg tgatagccgt
       61 cacatcagag cgaatatccg ccatatggtt caaattcaca tcgcggacag gatcctcctc
      121 cagaaagaag ccttcaatca gcttcagcga gctgctgata tcgtccatat aattgtctac
      181 gattctctct acctgaaccg ccgcctgatc gctggaagtt tttacattct ggatcatgga
      241 cgcccggtag gtggtgacaa acacgacaat tcccgccaaa agagaaaaaa acaccataga
      301 tactaccagg attgtcatga tcccggagct ggtaagtcct atcttccggt ctttcccttt
      361 catccgtcta tactcctctc cccgttttct gctcatgcct gtgtttcctc ttggctgagc
      421 cgccggcgca gcatattcgg cgatactccc tcatactttt taaagcagta gctgaaatag
      481 tgctgatcat tgtagccgca ggtttcagaa acctccttaa ttttcatggc tgtgttgaga
      541 agcagggttt ttgccgcctc cattctcttc tgtgtcagat aatccacaaa actctttcct
      601 gttctctttt taatcagaga actgaggtaa ttggggctga cgccaatctc cgtgctggct
      661 gacatcaggg aaagatctgc tttaaaatag ttatcttcaa tatggcggat agccttgtcg
      721 cagatgtcca tgctgctctt tgtcttctgc tctgaaatcc gatccctggc cgtcatgcag
      781 aagttgacga aatgatccgc cgcgtccttt aaggagctgt ccaaaaatac catctgctgc
      841 atgaacggat ccgactttaa agccgccgcg tctgactctg cagatacgga atacataatc
      901 cggcagacgc aggagagaat ctccaccagc atgaaattga ccttttccct ggaattgttc
      961 tcatcccgca ggtggccgaa tacctcccac agatattcct ccagctcctc cctggaaccg
     1021 ccccggatct tttcctcgat gctggccact accttcatga cataatccat gtccacgccg
     1081 gaaaacggct cctcatccgt aatatagcgg acgccgcccg ttttgcttct gctggcgtag
     1141 cgcatggcgt tcaccgcgtc tctgtaaccc tcggaaagct ctgtaaagcc gttcaggacc
     1201 cggctggctc ccacgctgca cttcaaattc agaatacggt cggtactctg gacaatatcg
     1261 tccgccaaaa tgtgcagata tttgtcaaag gacgccggcg ttgcccacag cacagataca
     1321 atcctgtctt ccagaaaaaa gctttcatat ttaatatact ttttcagaat actgtccacc
     1381 gaatggacat ggctgtgatc ggtgcagttg gcccccttct catcccagaa ggtaacggat
     1441 atcaccaggt aacggatatt ttcactctcc ggccgtatca tgccgcaggc cctggcctgg
     1501 ctgcagagcc tctcctccct ctccgggctg aaattcgtct gaaagctgtc taacagaaga
     1561 ggaagcagaa actcagaaat acccagctca ttttttcttc tctgggcaaa ctctgagaat
     1621 aaatgatcga tcttctgttt aatctgaatc agattctccg tcaaatcagc catggaaatg
     1681 ggtttcagca tatagctgat aatattgtac tggatcgcct gctgggcgta ggaaaaatcg
     1741 tcgaaaccgc tcaaaaacgc aatctgcgtg gccgggcgga tttccctcac ctgtctggcc
     1801 agctccacgc cggaaataaa cggcatcctg atatcggtaa gcagcagatc cggctccttc
     1861 tcgctgacca tctcaagggc ctccaccccg ttctccgcct cgcccactac ctgaaatcct
     1921 atctcctccc agttaatcct gcggataatc gctcttctta actcctcttc atcatctgca
     1981 actactattg tatacataaa tcctccgttt tctcactcca tcttctgcta ttctaccata
     2041 ggaagttacg aaattctata gaaggatgaa aaagccctgc ggacaggaat gttatttttt
     2101 tatcaatcca tttcctcttt tacagctttt atggtatact tttacccaat taacacaaac
     2161 atactactat acttacaagg agaaggatat ggagccacga aatcttactt tactgacaga
     2221 cctgtacgag ctcactatga tgcagggcta ttttcacgag aaggacgcca atgagactgt
     2281 cattttcgat gccttctacc gaagcaatcc ggatggaaac ggcttcgcag tctgcgcagg
     2341 gctggagcag gtcatcgaat atattaagaa tctccatttt tcagaagcgg atattaaata
     2401 tctcagaagc gtagggctgt ttacagagga tttcctcgac tatctgcgca attttaaatt
     2461 taccggcgac atctatgcaa ttccggaagg aacggtcatg tttcccagag aaccgattgt
     2521 aaaggtaatc gctccgatta tgcaggccca gctggtggag acggcaattt taaatatcat
     2581 caaccatcag agtctgattg caacgaaaac ctcccgcgtg gttcaagccg ctcagggtga
     2641 cggcatcatg gaattcggcc tgcgcagagc gcagggacct gacgcaggta tttacggagc
     2701 cagagccgcg atgatcggcg gctgcgtggg cacctccaat gtgctggcag gacagatgtt
     2761 tgacgttccg gtaaaaggaa cccatgccca cagctggatt atgagcttcc cggatgagct
     2821 caccgctttc agaacctacg caaagctcta ccctaccgcc tgcattctcc tggtcgatac
     2881 ctacgacacc ttaaactccg gtattccaaa cgctatccgg gtgttcacag agatgcggga
     2941 ggcaggcatt ccgctgaagg gctacggcat ccgcttagac agcggcgatc tggcttatct
     3001 gtctaaaaag gccaaggcca tgctggatgc ggccggattt acagacgcca tcatttccgc
     3061 gtccaacgat ctggacgagt atctgatcga cagcttgaaa attcaaggag ctgccatcaa
     3121 ctcctggggc gtgggaacca acctgatcac ctccaaggac tgcccgtcct tcggcggagt
     3181 gtacaagctg gccgctatcc tggatcggga aacaggcaaa ttcattccta agattaagct
     3241 gtccgaaaat acggaaaaag tgacaaatcc gggaaataag acgatttaca gaatttacga
     3301 tagagcaaat cacaagatta tcgctgatct catctgtctg gcagacgagg tttatgacga
     3361 gaacaaatcc cttctcctct tcgatcccat cgaaacctgg aagaagacac acctctcccc
     3421 aggctcctac gagatgagag agctgttagt tcccgttttt aaggacggcg tctgcgtcta
     3481 ccagtctccg aaggtcatgg aaatccgcga ttactgccgc cgggaactgg acacgctgtg
     3541 ggatgaatca agacgtctca tcaaccccca tgaggttcat gtggatctgt ccaatgaact
     3601 ctggcacatg aaaaaccagc tgctggacag ctatcactat aacaggtagc agccaaacat
     3661 acggatgaaa aaacgctctg acgggaaaat tcccgccaga gcgttttcta tgacacaatt
     3721 aaaaactcct tccaagacat caattacaat gttcaggaag gagtttacat ctaaaaacct
     3781 ttgttttacg ctatattctc ttatctctcg tctgtatccc tgcgcaagac cttacaggtc
     3841 ttgcttgggt tcctctaaaa atgctgctgc agcgatcggg aatcccggac tcctctttgc
     3901 tgcgtccagg cagcgctcgg tttcactcgc tttattcgtc ccagttgtgg taggtcgcct
     3961 gcacgtcgtc atcgtcctct aagagatcca gcagacggtt catcttctta atggactcgt
     4021 cgtctgtcag ctctacccag gtctgaggga tcatagtcac ctctgcctcc atcatgggga
     4081 tattcttggc ttccagagcc tcgcgcactg cggagaaatc ctccggggaa gtgaggatct
     4141 catagctgtc ctcctcctct gcaaagtcct ctgcgcctgc gtccaaagct tccatcatca
     4201 gagtgtctgc atccagctcg cactcttcct tatcgataat aatctggccc ttcttgtcaa
     4261 acataaagga aacacttccc tgtgttccaa tattgccgcc gccctttgtg aaagcgcttc
     4321 tcacattagc tgccgtacgg ttcttattat ctgtcagagc agtgacgata acagccactc
     4381 cgttagggcc atatccctcg taggtcagct cctcgtaatt tacggagttt gcgtctcctg
     4441 ccgccttctt gattcctctg tcaatggtat cgttaggcat attgttggcc tttgccttgg
     4501 cgattacatc gcgcagacgg ctgttgttag ccggatccgc tccgccttcc tttacagcaa
     4561 ctgcaatctc acgtccgatg acagtgaaaa tctttccctt cgctgcgtcg ttcttctctt
     4621 ttttgtgctt gatattagcg aattttgaat gtcctgacat aataacgctc ctctttttga
     4681 atcatgtatt ttttacagaa tgtctggaaa gacgttcttt ttgctcaaaa tcttttttat
     4741 tctatcacta aaccctgagc ttggcaagta ttaaacagga gaatcggcca gtctacagct
     4801 ctgcggccag attgcgcagc cacttcttct gcctgtatct ccagtagccg aaaacagcct
     4861 tatagacctc ctccagcatg accatagcgt agacgatgtg aatggggaac ccaaagaaca
     4921 ggcctcctaa aaacgccatg ggaactccta tcatccatac gccggaacag tctaataaaa
     4981 ggcacatttt agtgtcgccg ccgcttcgca ggatacccac caccataacg tagttgaaca
     5041 tcttaaaggg cataaacaga gcgaacacaa taatacagcg gctgacgctc tcggcaatct
     5101 ccggcgtgat attgtagacg ccgataatct gccaccggat ggccacgcag aaaagagctc
     5161 ccaggatggt gacgataaac tggagaatca ggaaattctt cgcataccgc tccgcccgct
     5221 tcagttttcc ggctcccatc tcatttccca tgattaccgc cgtagccgcg ctcagtccct
     5281 ggaacaggac cgtgacaata tcctggatcg tggtggcgat ggtgatcgct gccaccgcat
     5341 cgtttcccat acggccgtag gccagagagt acagagtggt tcccagaccc cagataaact
     5401 cgttggcaat aaccggggac gtggtgctga aaaactgaac aagaaattcc ctggaatagc
     5461 cgaacatttc cttaaattta gcggctacag gagcctttcc cagataaact accagaataa
     5521 tggacagggc ctccaccagt ctggccatca gggtagccag ggccgctcct gccgctccca
     5581 tggccggagc gccgaagttt ccataaataa atgtgtagtt aaagaaaata ttgataaaaa
     5641 tcgtgcagct gctgattact accggggctt ttacccgtcc tgtcgctctc agcatggcta
     5701 caaaggtatt gctgacagct gtggcaggat aggaaagagc cacaatcgtc agatatccgg
     5761 ctcctacctg aatcgcgtcc tcactggcag taaaaatacg catcactgct tctgggcaga
     5821 ctacagctgg tacgagaaag gcgatggacg cagcgactgc cagagacagc gccagtccta
     5881 ctaccttttt aatattttta atatctccgt ttccccagta ctgggctgcc agcacaccag
     5941 atccgctgac aattccgaat accagaagag tgaatacgaa gaataccttg ttggccagtc
     6001 cgactgccgc tatagcagta gctcccagag agcctatcat catcgtatcc accagattga
     6061 cgatggtgtt taacattccc tgcatggcca caggaagcgc aatccgtact gcctttttca
     6121 ggaaaatccc gtctctggcc atcatcttta catcataaaa aattcctttt tccataaatt
     6181 tctgctgctc tctcccctag ctgtcttcgc ccggtttttc tatttctccc cggctgcgga
     6241 cagctctcac tgtatgaatg actttatttt ctacagaaat gacctggaac agatagcttt
     6301 tgtaggtcac ctccggcgtc tctccctccc tgggaacacg gtttaatctg gaaatcagga
     6361 atccgttcag ggtgtcgaag ttttcatagt cttcctcctc gaactcgatt tccagctctt
     6421 ttcccacgtc ctctaacgga gtcaggccat cgaaaatcag gcttccgtct gcttttctgg
     6481 agatcagctc ctcgtcctcg tcgtactcgt ccaggatatt tcccactatc tcctccagga
     6541 tgtcctccat cgtaacgatt ccagccgtct ggccgtactc gtctaccacg atttccatgt
     6601 ggatcttctg ggactgcatt tccttaaaca gcagattaat gttgcgggtc tccggaatga
     6661 aatgaggcgt tctcaaaagc ccctccacct catccaggcg cttgtccaga ttttcttcct
     6721 tctgagcgca ggacagcgta tcgcgaaggt gcagaatacc cttaatatcg tcgatgtcct
     6781 catcgtacac cggaaatctg gaattgcttc cctctgtcag gatgtaggcg accgcctctt
     6841 taagcgtcat ggaaacgtca agcgccacga tctgctttct tctggtcata atatcgccgg
     6901 catccttatc tcccagctct acaatgtttg tgatcatctc ggcctcgccg gcctccagaa
     6961 ctccctgctc atggccctcg ttgaccatca gcatgatatc ctcctctgtc acgctgtcgt
     7021 tcttgtcgtg cagcccgatt cccagcggct ttaaaatcag ccaggacaat cccgacacaa
     7081 gccaggcaaa cggcttaaac agagcgacta tcacagaaga aacacctaca tagcggtaag
     7141 cccactgctc cggatgtttg gaagcgcacc gcttcggaac tacaattcca aggctgatca
     7201 gagccgccag cagcataaca gccgccgctg ccgtagcagc gatcagggaa aagccctctc
     7261 ccgtctcccc ggttctatgt atcagcagcc ccagcagcgc gcctgcctct tttaaaatca
     7321 tagctcctga aaccaggccg attaaattag tcacaatctg cacggtgcca ataaactctg
     7381 ccggctggct gattaccgcc aaaagcctct ccgccttctt attcccttcc tgggcctctt
     7441 tttccagcgt tcctgaattt aaatgctgga tagcagctcc gaaaccgtac aaaacggcat
     7501 ccagcagaat aaacgctgca aaaatcacaa tacttaaggg ccaatacccg tcgtccataa
     7561 ttaaaaatgc tctcctttgt cttcttttct tataaagtaa aaaggcagaa tatccggact
     7621 ctgccctatt ctgccactat accattctat tctgcgttcg tcaaccttaa ccgcccggca
     7681 gttgtatgta ttttcctgct gccaaaggcc gttttattta aagctcaagg ctgaccatca
     7741 gcgcctggtt cacccgtcca agcagctcct cgtcaatatg gcagatccgc tctctcagtc
     7801 tctgcttgtc aatggtgcgc agctgctcca ggagaatcac ggaatctctc accataccgc
     7861 accgcctggt atccagctcc acatgggtgg gaagctttgc cttattcatc ttagaggtaa
     7921 tcgccgcgca gatcacggtg gggctgtgct tattgccaat atcgttctgt ataatcagta
     7981 ccggacggac gcctccctgc tcggatccta ctaccggacg caaatctgca taatagatat
     8041 ctcctcgttt tataaccaac tgtctcactc tccgtcattt cagtttatac ctccagtatt
     8101 gccttatttt ctgaatggta ttcaaaactg cggaaagatt tattttctct tcccctttat
     8161 tatatgagag tgttctgtcc ctggttcccc caggtgtaaa tacggggaac ccgtttcccg
     8221 atgaggcagg gaagttcata gtggaagccg ccgctgacat cagccagctc ctccatggtg
     8281 atttcctcct gcccgtcgcg gcctacaaga gtaacctcgt cccatttctc agcctcagga
     8341 atatcagtca cgtccgccat aagctgatcc atgcagaccc gtcccagaat cctggcccgc
     8401 tttccgcgaa tcagcacctc tccttttcca gacgcgcctc gcgggtagcc gtccgcatag
     8461 ccggcgctga ccgtggcaat cctcatggga cgatccgccg taaaggttcc cccatagctg
     8521 actgctgttc cagacggaat ttccttaata tatgtaatgc ggctcttaaa ttccataaca
     8581 ggaagcaggc ggacacggct gtgatccacc tccccggacg ggtacaggcc gtacatggcg
     8641 atccctgccc tggctccgtt catctccgag cctttcggca tccggtggaa atccacgatt
     8701 ccggcgctgt ttaagcagtg gcagaacagc tttttcctgc ctggttccgc cttctccaga
     8761 agctgcgata cggcggcgga aaaatccctg aacttctgaa actgccgctc tgcccactgc
     8821 ttgtcaagct cgtctgccct ggcaaaatgg gtgaacatgc cctctatctc aatccctttc
     8881 atctggctga tgcgcctgat ctcttctaac gcctgctctc ccggctgaaa accaatccgg
     8941 ctcatgcccg tatccactgc caggtggatc ttcccgagga tccccgcctg gctggcgatc
     9001 tctgaaaagg ccgccgccat ttcctcctcg aaaatcaccg ggcggatatc agccgccaaa
     9061 agctcataaa atctctcttt tggcacgctt ccaagaacca gaaccggttt taaaattcct
     9121 tcccggcgca ggcttaacgc ctcgtctgcc gtagctgcgg caaaggccgc cgcataggga
     9181 tcagccgctc tggcagtctc tcccgcgccg cagccgtagc cgtcggcctt caccacgccg
     9241 atgatcttcg tcccttccgg cagattctcc ttcatggact tcatattctg gcggatccga
     9301 tccaggtgga ccaggacaca gatccggtca aagtcatgtt ctcttccagc tgtcacgttc
     9361 tcttctttct tccacatact gcttcttccc tctccacatc tgccaggctg tccgccagat
     9421 ctctggccag cacgccgttc tctcctaaag ccttctctgc cgcctctccg gccagtccgt
     9481 gaaggtaaac gcccaggacg gctgcctggc cttcctccat gcccatggca atcaaagccg
     9541 ccagcactcc tgtcagcacg tcccctgaac cggccttagc catagctgcg cagccgctgc
     9601 tgttaatgta aatcggctcg tcctttctca ccaccacggt ggccgcgtct tttaaaacta
     9661 tgataacccc atatttttcg ctgtagtcct ccgccgcttt cgtcaaatca gcctggattt
     9721 cttctatctc cagcccggaa agtctggcca tctcccccac atggggcgtt accagcacat
     9781 tttccgtaaa atattctgac agggaaggat tttccgccac aatattcagg ccgtccgcat
     9841 ccaggacaat cggcacaaag gctgataaaa ggacctgctg taccagacgc accgcccagg
     9901 gctcctttcc aagccccggc cccagcacaa ccgcatccgc ccagccgcac tccttttcaa
     9961 tctttcctaa aaactgttcc ggctcttcca gagcttcggc gcaatcataa acggaaagga
    10021 cagcttccgg aatgagcgtc tgtaaaatct cccggttctc cgccggcgtc agaattttta
    10081 caagtccggc tcccatacgg taagcggcca gggcgctcag ataggccgcc cccgccatgc
    10141 cgggagatcc ggcggcaatc agcacatgtc cgtacgttcc cttgttggac cagggtttcc
    10201 ttcctgggag aagttctaaa tcctccggtc cgcaggtcac ataccgcctt cctgtcagac
    10261 gctctgccgg acagggagga aatccgatat ccttcacaac cacccgtcca ctgtactctc
    10321 ttcccggaaa cagggaaagt cccacctttt taaatccaaa cgtcactgtt aaatcagctt
    10381 ttacggcagt tcccatcacc tttcccgtat cagaatggat accagacgga atatccacgg
    10441 ccacagtaag ccgcggcttc atatcctcaa tcgtctcaat catatcccgg taagcccctt
    10501 ctacgttccg cgaaagtcct accccgaaaa gggcgtccac tgccgcctgg caggttcccg
    10561 gaatgaagtc ctccgcctcc atggcagaaa gccccagctt ttcattgatt gacagctgaa
    10621 gtttcagctc ctctgtgcgg ctttcctccc tgcccactgt aacaaccgtc acatggtagc
    10681 ccctgagaaa aagcatacgc ccgacggccg ctccgtccgc tccgttattt cctgttccgc
    10741 aggcaatcag aatctgatcc tccctgaaaa gctccggctc catctcttcc accacggaaa
    10801 gcgccgcccg ctccatcagt accagagatg gaattcccac ctcctgaatc gcatactgat
    10861 ccactgcctt catctgttcc cccgttacca gctgcctcat ccttgtctcc tccttctcct
    10921 attgatcagc ccgctccccc acggcaaagg ccgccgcata ctctgcagta tttgtaatgg
    10981 acacatgaat ctgctgaatc gccagctcct cagccagctt ttttgcccct ccgtgaagac
    11041 gtacaaaggg ctttcccaga tcgtccctca gcacctcgat ctctctgggg ccgaagcttc
    11101 gaaatcccgt ccccagggcc ttggacaccg cctccttaac ggcaaaagtg ccggccagcc
    11161 gggaataatt ttccccggcc tgctggcact cttcctgggt atagacacgc gtcaagaaag
    11221 ccttcttttc acaggccctc ttaatccgcg caatttctat catgtctgtt cctacccctg
    11281 ctatcatttt gcttcttttc cctttgcctg acttttttcc ctctccttct gatcctgcat
    11341 gctgcatacc cgataggaca gccgcatcag gctctcggac agatggacgt tctccaccac
    11401 cacgtcgtcg ggaaccacca gatccgtgtg ggcaaaattc cagatggcct taattccggc
    11461 cttcacaagg cggtccgcaa tctcaggcgc cttggacttg ggaatggtca gagctgcgat
    11521 ctgcacgtcg ttatccttga taaactgctc cagatcctca attcctctta tctctacgcc
    11581 gcggactaca aggcctacca gccttgggtt tacgtcaaac attcccttga tcaggaagcc
    11641 ccggcgttca aaattcgtat agttggcaat ggcctgtccc aggtttcccg ctcctataat
    11701 aatcaggttg tgctgcctgt caatgccgag aattctggca atctctgaat acagatattt
    11761 tacattatag ccatagccct gctgcccaaa tccgccgaaa ttgttcagat cctggcggat
    11821 ctgagaagcg gtcaccttca tcctcacgct cagctcgttg gaagaaatcc gttctacccc
    11881 ctcttccagc aattccccta aatatctgta atatctgggc agccttgaaa taaccgcctt
    11941 agaaatctct ttctgttcca cggcttttct tcaccttcct ttactttaac ctggcgtttt
    12001 cccgtatcgc tccgttcctc aggaaaatgc gttatttact attatagcat atgacaaatt
    12061 attgtcaaat aaaagttctg cagattttcc agctgtcttg caaatattcc cttcttatat
    12121 tatacttgtt gcaggttttt gattttagac atacaggagg acaacatgat tttatcatgc
    12181 agcaatattt caaaatcgtt tggaacggat tcgattttaa atcacgtatc ctttcacata
    12241 gaagagaggg aaaaggcggc cgtcgtaggt attaacggag ccggaaaatc tactcttctg
    12301 aaaattatcg taggagagct ggcgccggac gagggttccg tagtcattgc caagggaaaa
    12361 accctgggct atctggccca gcaccaggat ctggacagcg gccagaccat atacgacgag
    12421 cttctggagg tgaagcggcc catcattgag atggaggagc gtctccggac tctggaggta
    12481 aatatgaagc gctcccaggg cgaggagctg gaaagccttt accagaccta cagccgcctc
    12541 agccacgagt tcgagctggc caacggctat gcatggaaaa gcgaaattac cggcgtgtta
    12601 aaaggactgg gatttctgga ggaggaattt tcaaagcctg tctccaccct ctccggcggc
    12661 cagaaaaccc gcgtttccct gggaaaactg ctcctgtcca agccggatat tattcttttg
    12721 gacgagccca ccaaccacct ggacatggag tccatcgcct ggctcgaaaa ttatctcctg
    12781 aattatcagg gaactgtcgt cattgtagcc cacgaccggt atttcctgga tcgggtggtg
    12841 acgaaggtgg tagaactgga caacggctcc tccaccgtct ttcagggcaa ttactcggcc
    12901 tacagtgaaa aaaaggccat gctgcgggcc agcattttaa aggcctactt aaaccagcag
    12961 caggagatca agcaccagga ggaggttatc accaagctgc gctcctttaa ccgggagaaa
    13021 tccatcaagc gggcggagag ccgtgaaaag ctgttaaata aaatcgagag gattgaaaag
    13081 cccacagagg taaacgacgc catgaacatc accctggagc ctgacattgt cagcggaaac
    13141 gacgttctga cggtcctggg ccttaccaag ggctttgacg ggcagactct tttttccgac
    13201 gtggactttg agatcaagcg gggggaacgc atcgccatca taggaaataa cggaacggga
    13261 aaaaccacga ttttaaagat cattaacggc attctggccg ctgacgcagg ggagatccgg
    13321 ctgggttcca gagtccatat cggatactac gatcaggagc atcatgtgct ccacagcgag
    13381 aaaactctgt ttcaggagct gtcggacacc tatccgaata tgaataatac tcagattcga
    13441 aacgtcctgg cagccttcct gtttaccgga gacgatgtgt ttaagctgat cggcgatctc
    13501 agcggcggag agaaaggacg tgtctctctg gccaagctga tgctctcaga ggccaacttc
    13561 ctgattctgg acgagcccac caaccatctg gacatcacct ccaaggagat cctggagaac
    13621 gccctgaccc actacaccgg aaccgttctc tacgtctccc atgaccgata ttttatcaat
    13681 aagacggcca ccagaatttt agatctgact cacaataccc tggtcaatta tattggcaat
    13741 tacgactatt acctggaaaa gcgcgatacc atggagcagc tgttctccgc ctctcccgca
    13801 gcttcttcca aaccatcgga aaacaactct caggcagcgg ccctcgcggc ttccggcccg
    13861 gtaaacgccg cctctcttcc ctggtccggg gacaggggaa acgcctcctc ttctgacagc
    13921 ggagattcct ccggaaaaac agactggaag cagcagaagg aggagcaggc gcgcctcagg
    13981 aagcgccaga acgagctgaa aaaaacagaa gacgccatcc accagttgga aaccagggac
    14041 ggcgaaatcg attctcttct ctgccaggag gacgtctttt ccgacgtggc gaagctcatg
    14101 gagctgaacg cggaaaagca gtctattgcc ggacagctgg aagaactcta tgaaaaatgg
    14161 gaggagctgg ctgaggatta acctcagccg gctcttttta ggaaggaaac tctgcctttc
    14221 ccatattaaa ctctgtgatg cccatatagc cgggcgctat gctgtattcc gggaatacta
    14281 aaaccacctc ctggttttca ttgatataaa actgcgtcgt ctcgtctact gtggtaaacc
    14341 cctccgccat tccatcgtca ttgggttcaa agccaaaaaa catctggttt tcatctgccg
    14401 ccatgcgcgc ttcaatctgg cgcactacct ccttattgca ccgctccaca tagccgcttc
    14461 ccagaacgtc cttcagggcg agcaggcggt cctgtttcaa atccagattg taataatacc
    14521 gctcctccat cgcgttaacc cagcctttaa aggtaatcag ttccagggag agaacctcct
    14581 cgctctggta ttttacctgg tagtccacag acagatccat ctggcggtcc gcccactcct
    14641 cctctgtgcc tccggctgca aaaaaagctt ctttataggc ggcaaattcc ttcttgccct
    14701 ctgcaagata gttgtccaca atctgttcaa tctgctcgtt cacgcttttt gccgtgccgg
    14761 actggcttcc cgacccatcc gggcctccag tctccacaat tgctggaatt tccgcgtcaa
    14821 tattgtagtc ctgatctgcc tggtgatacg aacggatcgt cagaacttct gccagaaatc
    14881 cgattcccgg aatctgtttc atcgtttctg caaacgcctg gttcgtattc aatccaatgg
    14941 taaaaacaac agcggctccg gctgcggcgg ctgtgaatct tgccgccatt ctctgtgaaa
    15001 aacggatcgc ttgagcgctt ctcttttcct ggctcttctc cggaacattc ccgcccctgt
    15061 ctttgtcaga ttctttttct tctgcttctt tttctctgcg ccttttttcc gcctcggcaa
    15121 tggactgtct cactatctga tccagttctt caggaatctc tatgctgtcg tatatgccct
    15181 ttccatcttc cggtttcata gcgcttcctc ctttaatctt tttttcagac gctccagcga
    15241 tgaatacagc ctgtatttca ctgtattcag gtttacatcc gtaatctctg caatctgctt
    15301 cagcgttaaa tcctcataat aatgaagaat gacaacggtt cggcctggat ccggcagatt
    15361 cctcactgcc tcatagacct ccctctccct gtcataggct ggttctgtgt acgcctgctc
    15421 aaacacttcc ccatctgccg aaagctcttc tcttttcctt gccctcagaa tctggagcgc
    15481 ttcattgact acaatcctgt aaaaccatgt ctttactgcg tcctgattgc gaagggtatc
    15541 gcatttttca agtcccttca aaatcgcgtt ctgcaccaca tcaagagcag cctccctatc
    15601 ccctacatag ctgtaggcca ggcggtaaaa tctgttttgg ttctctataa tgtaggcagc
    15661 cacgctgtca tatagattct gttccatgct ctctgccttt ctaaatttca atcccattcg
    15721 tttctgtatc tattccttct agtattaaag atgataagcg gaacaaaaaa gttggggctt
    15781 tccgcaaaaa tactgcgaaa aaccccctat cttcctttca ggatcggatt caattctgga
    15841 tccagggccg gaccaaaggc gcctccggcg tccatctctc cctcctccgt catatcccag
    15901 acagatgggc gcagccctgt aaaatcaacg ccaagcattt catcaaacgc cgcgcacagc
    15961 tctggagctg tcatctgcat ctcgcttcgt atctccggat tgcagtaatt ctcaaataaa
    16021 acgccgaacc acgactcata atcgtcctta aaataatctg gaaggctggc accggaagag
    16081 atctccccgg aaacagcata cagctcctct gccttctcct tctgctcctg gccagcttct
    16141 accgcgccgg cagcatactc cccaaaggct ctcgtcagag actccggatc cgtaaattta
    16201 atcttcttat accgctgatc tgtcttatgg tatacatagc agacgccctc gtccgtcata
    16261 ggagcctcca tatacctccg atctgtatag tacataaatt cccagccctc tgccagaaaa
    16321 cggtccatcc actgcctggg aatattctcc agggccttcg tgacagcttc cttttcctcg
    16381 tcggacggct ttctctttcc ctgaatattc atatcatagt caggatttct caggccgtcg
    16441 gaaccatagt aggaagtgcc gatatactgg cccgccgcca gctggccgtt tgagtgaaag
    16501 taatacttgt ggccatccac catccgccac ccgtcgtcat acaaaacacc gttcgaatcc
    16561 agccagtacc agactcctcc cgtgttaagc catcccgttt ttctcgtccc gtcctcattc
    16621 agatagtacc actctccgtc ctcgtggctg tagagccagc ctgtggccat ccggccggta
    16681 tcctcattaa aatagtacca ctttcctttg attttattcc atccggccgc cggatatccg
    16741 tcctcatcca ggtaatacca gcgtccgtcc caaagcagcc agcttttctc caaacaggtt
    16801 ccgtcctcca gaagataacg gctgtccata tcgtcccctg tccacgttcc cggaatcgaa
    16861 tattctgaat tttcctgctg cagaacctgc tctcctgcct gcgcgcccag ggcggagcaa
    16921 gggaaaactg ctgccatcag gcacaccgct cctgccgctg ctgccatttt cttcaaggcc
    16981 gtctcctcct tcctgtattg tcctgctgac actgtctttt ctttatttta aacgaatccc
    17041 gcggaaaagt atagcaaaaa attcttacat catttatact aaattctgaa ggaaggtgat
    17101 ttcatatgaa tataaggcgc atactggccc tggctggcgt ttttcttatt ctgctgctgt
    17161 acggcgcttc cctggtgctc ggaatcatcg gaagcccaaa agcgctggat cttctgctgg
    17221 cagccctgtt ctgtactatg gtggttccag ccatgatcta cggctgcggc gttcttctga
    17281 aaaattccgg ccgttccgga aaggacagcc gctaaaagcg gcgggaaaca accgcaaaag
    17341 actgcaaaaa ggccgccagg cggagggaat gaatcctctc tgtctggcgg cttcttacca
    17401 tgcagactct tctctccggc cgtcccggct ggaaatgtct actttctcac aataatctcg
    17461 tctcttcccg gtccattgga taccatagta atcggaacct ggatttcctt ctcaatcgtc
    17521 tcgatgtaag cgcggcagtt ctccggcaga tcctcgtaat tcttgattcc tcggatatcg
    17581 ctcttccatc ccggcagagt cttgtataca ggctttgcct tctctaactg acgtgtagtt
    17641 gggaagtctg ctgtcacctt gccgtcgatt tcgtatccca cgcagatttt cagctcatcc
    17701 aggtatccca gtacgtctac aactgtcaga acagcctctg tcgttccctg aatgcggcat
    17761 ccgtagcgtg tagccactgc gtcaaaccag ccaactcgtc tcggacggcc tgtagtagct
    17821 ccgaactcgc ccttgtctcc gccgcggcgt cttaactcgt ccgcctcctc gccgaaaagc
    17881 tcgctgacaa acgcgcctgc tcctactgcg ctggagtatg cctttacaac ggttgtgata
    17941 ttcttaatct catacggagg aattcctgct ccaatcgcgc cgtatgcggc cagtgtggag
    18001 gaagaggtta ccatcggata aattccgtga tccggatcct ttaaggaacc taactgtccc
    18061 tctaacagga tattcttgcc ttccttgatc gcctcatgca ggaatgcaga aacatcgcac
    18121 acataaggct caaccattct tctgtactcc ttcatctctg caaagagctc atctggattt
    18181 aacagcggct tatggtataa atgctctaac agcacgttct ttgtctcgca cacgcgctta
    18241 atcttatcgt aaagatactc ctcgtcaaac agctcgctga cctggaaacc aatcttggca
    18301 tacttgtcag agtaaaacgg agcgattccg gactttgtgg aaccgaaaga ctttccgccc
    18361 agtctctcct cctcgtactc gtcaaacagc acgtgataag gcatcagaat ctgcgcacgg
    18421 tcagaaacca gaatcttcgg ctgcggaacg ccttttttct taatgtcctc gatctcatta
    18481 aataaaaacg gaatattcag cgcaactccg ttgccgataa tgcttgttgt gtgatcgtaa
    18541 aatacgccgg acggaagcag atgaagcgca aatcttccat agttattgat aatagtatgg
    18601 cctgcattgc ttcctccctg aaaacggatg atgatgtcag attccttggc aagcatatcg
    18661 gtaatcttgc cttttccctc atctccccag tttgctccaa cgattgctct taccatgtac
    18721 ttactcctct ccggatgccg tcctctctgt ctgaaacggc tcttttctgt ccccgtctgg
    18781 ggcgtcctgt tcattactta catattatat atgacttctt cacataagta aaatcaatat
    18841 ttattatgag ccatataatt tattcttata tttctgtcct gtctgctttt gagtcctggc
    18901 cgccggggga aagggtttcc agaagcttct tagccgctgg agaaagcgga tttttcagag
    18961 aagtgataag gcagaagctc ctcttttcca tggcatgccg gaatttcagt tcaaacacat
    19021 cctcccgctc cagtgcctcc ctggcgaact ctgacatcag acagccgatc cccagatttc
    19081 tcttcacaaa ctgcacaatc atatcgctgg tggccagctc aaattccggc tccagggcca
    19141 cgccttcctt ctccaggtat tgatccataa accgcctggt gctggtcttc ttctccagga
    19201 aaatacaggg gtaatccttc agctctctgt aatccagctc ccgcccttcc agctgttccc
    19261 tgaaccggct tccggcaata aaaatatttt caatctgccg gacgggaact gcccgcatct
    19321 cctcccgccc ttcaaagggc gtgctgacaa tcccgaaatc aatggcgcca ttttccagag
    19381 cctctatggt ctccggcgta gggccgttgg acaccattac cttaattttc ggatactgct
    19441 cgtgaaactg ctccagataa ggaagcaggt aaaactgcag cgtcatgtcg ctggctccga
    19501 tccggattac gccggtatcc agacatttta actgctttaa catctcctcc ccgtcccgta
    19561 tgctctcgat tccacgcttc acatagccgt agagcagttc cccttccctg gtgaggcgca
    19621 cccccttggg agtccgcaga aagagcttcg tctccagctc ccgctccaga tgcttcaccg
    19681 cctggctgac tgcaggctgg gaaatgcaca gcgtctctgc cgccatggta atgcttccag
    19741 tggccgctgc ctggtaaaat accttataat actccagact gatgttcaat ctctcccctc
    19801 cctccaggtc tgtgcaaaaa acgcatgaga caggaaagag aagatagttt cccactgaag
    19861 caaaacctat cttctctctt cttcactatg cagggccgtc tccggccttt tcctgaacgc
    19921 gccggcggcg tctgccgttt agacgttaat ctcagccttc acgcccagaa tttctttatt
    19981 ctcctccaga acaggacgga tgacctcgtt aaggaactcc tccacctgct ccttggctct
    20041 tcccgtatag cgggacggat ccatggtctt tttaagctca tccagcgtca ggttaaaggc
    20101 cggatctgca gcaataagct ctaacaggtt attgtccagg cccttctcct tcacatttct
    20161 tccagcctcc atggacaggg tgcggatctt ctcatgaagc tcctgtctgt ctccgcctgc
    20221 cttaacggcg tccatcatga tgttttctgt agccataaac ggaagctcgg acatcaggcg
    20281 cttctcaatc actttcgggt ataccacaag gccgtctacc acgttcaagt agagatccag
    20341 aattccgtcg atggccagga agccctccgg aatgctgaga cgcttgttgg cggaatcgtc
    20401 cagagttctc tcaaaccact gcgtagaagc taccatcatg ggattcatca tatcagccat
    20461 cacatagttg gccagagaag ccattctctc gcttctcata ggatttctct tgtaagccat
    20521 ggcggaagat ccaatctggt tcttctcaaa cggctcctcc acctctttta agtgctgaag
    20581 aaggcggata tcgttggaga acttatgggc actctgggca atgcctgcca gcacgcttaa
    20641 cacgcggctg tccacctttc tggaataagt ctgtccagat acaggatagc agccctcaaa
    20701 gcccatcttc tgagcgatct ttctgtctag ctcccggcac ttttcatgat ctccgtcaaa
    20761 gagctccagg aagctggcct gggttcccgt cgttcccttg gaacctaaca ggcggaggga
    20821 gcccagcaga taatccagat cgtccagatc aagcttcagc tccatcagcc agagtgtggc
    20881 gcgctttccc acggtagtcg gctgcgccgg ctggaaatgg gtaaaggcca gcgtcggctg
    20941 ggccttgtag cggtccgcaa acttagccag ctcgtccatc acgttgatca gcttctttct
    21001 caccagcttc agggcatctg ccataataat aatatccgtg ttgtctccaa cgtagcagga
    21061 ggtagcgccc agatggataa ttcccttggc cttcgggcac tgaacgccgt atgcgtatac
    21121 atgggacata acgtcgtggc ggaccagctt ctctctctcc ttggccacgt cgaaattgat
    21181 atcgtccata tgctccttca gctcgtcgat ctgctctttc gtaacaggaa gtcccagctc
    21241 gttctcagcc tctgccagag ccacccagag acgcctccag gtacaaaact ttttctccgg
    21301 ggagaaaata tactgcattt ctctgcttgc atagcgctcg gaaagagggc tcacatatct
    21361 gtcgtgcata gatttttacc tcgccttttt attttttttg cattgctttc tcattcctga
    21421 cagtctctat tataagctat atatataaaa cgctgtcaat tcagtagaaa ttataatgca
    21481 atttgttttt aaaatcaacc ggaatccgct ctgcctttta ttaaaataat taataagagc
    21541 tttcgctgta aaatgttatc tcgccgtcct tcaggcggaa tataatccca aacttccgtt
    21601 ttccttccgc ctcatcctgt gaggactgcc cgtctttttt cggcgcttct gtttcctgaa
    21661 tctcttctat ctcaaacagc cgtccgcccc aatctgccag aatcagcaga tatccggcag
    21721 ccagcgcggc gcagcagaga aaggcaagac gccttgtcct ggctcttttt ccgagcctcc
    21781 gcctcatata ccgtctccgg atgcggcgca gtccggattc attcccgttt cctgcgcgtc
    21841 ctctgatttt tctgtttttc atgtatccca cctgccgcgc ctctccaggt acagcgggga
    21901 tcgtctctgt cttaactata gcgaattttt cagagaatgt aaatagcgaa atccggtgga
    21961 atgaacgccg tttttactcc tgaacgctcc cacagaaaaa aggataggag ccggctccta
    22021 tcctttcgca tgtttctaat tttccagttt atcttatcga tcgctctgat tgttctgctc
    22081 tgtatccggg tctctctctt ccaagccctc ctcagctctg gtgacgccct cctcaatcca
    22141 gtcggcagta tcttccgccc cgtctttcag atcgtctcca atgccctcca gaactcctgt
    22201 gctctcctca aagtctctgt ctttctccat gccgtccttt tctgctcctg gcatagaacc
    22261 gtcggaaggc ctggacgcag aagtttccgc tgtctcggga actcttgacg cgttggtggt
    22321 attcttcaca tcctcttttg agccgcacgc agtcagaaac acaaatacaa aggccagaca
    22381 catggctgtt aaaacctgct tacatttttt cataatgaca actcctttct aagcctagta
    22441 tggacggcct aaaagggaat tatacaggtt tctggcagct gttattttaa tttttcagaa
    22501 aaatcagcca atcacgtccg ccatagaata caggccggcc ggctttcctc ccagaaattt
    22561 agccgcctga atggctccct tggcaaaaat tgccttggaa taagcggtat gagtgaacgt
    22621 gatcacctcg tctgtgccgg caaaaatcac gtcgtgctcc cctacgattg tgccgccgcg
    22681 gacagactga attccgattt ctttcgaatc tctggggact ctctcactga accggtcata
    22741 tttataatga caggtattgt ccagagactc gttgatcgcg tctgccagag ccagggctgt
    22801 accgctggga gcgtcgatct ttttattgtg atgcttctcc acaatctcca cgtcaaagcc
    22861 cgccggatac agcacagggg ctgcctcctt taacagcttt aacagtgtgt tcacgcctaa
    22921 ggacatattg gcagagcgca gcacaggagc cttcttagat acctcctctg ccttctgtgt
    22981 ctgctccttt gaaagtcctg tcgtgcagag cactaccgcc atgcctgtgc gggcgcagta
    23041 atctaacagc ccgtccgttg ccttagcgga agaaaagtca atgattacgt ctgcctcttc
    23101 cttcacctcg tccaggctct tatagaccgg gtagggacag gttccctctt ctgaaatatc
    23161 cactcccgct gcaatcacaa gctccttatc atccttcaca agatctgtaa tcacacgtcc
    23221 catcgctccg ctgcagccgt gcataatcgc tcttaccatg attcttcctc ctgtcgtctt
    23281 ctcaaatgtc ttctcgctcc aggacgtctg tgacgctgtt ccctggtttt ccctgttttt
    23341 aaagaagtcc gtaatttttc atagcctgaa tcagtctctc tctgtgttcc ggctccatct
    23401 ctaccagagg ctttctatag cctcccacgt tctttcctaa caggttcata gcctccttaa
    23461 ccggaatcgg attcacctcg cagaacagag cgttgattaa cggaatcgcc tgcagctgca
    23521 gcttcatgct ctcctccact tttcccttaa aatacagatc gcacatatcg tggacctttc
    23581 tcggggcaat gtttgagagg acggaaatta cgcccttggc tcccagagac agcatcggca
    23641 cagtctgatc gtcgttgccg gagtaaatat ctacccatcc gttggacagg ctggcaattt
    23701 tggcgatatc agagaagttt ccgctggcct ccttcactcc cacaatgttc tccacattct
    23761 tgcagagcca cacaatcgtc tccggactca tattcacgcc ggtacggctg ggaatattgt
    23821 agaggagagc cggaatcttt actgcctgcg caatatcgga aaaatggacc ttcaggcctt
    23881 tctcgcttgt cttgttatag taaggagtca ctaaaaggat tccgtctgct cccgcctcct
    23941 cagccgcctg ggacaggtac atggaagtat ctgtatagtt ggagcctgtt cctgcaataa
    24001 cagggattct cttatccacg atattgcaga caaactgaat tgcccggatg tgctcgtcgt
    24061 ggctcatggt agcggactct cccgtcgtgc cgcagactac gatactgtcc gtacctccgg
    24121 caatctgctc ctctaccagc tcctcaaact tagaataatt gatctctcca ttttccttaa
    24181 acggtgtgac aatggccacg cctgctcctt caaaaatagc cataataatt tcctcctctg
    24241 ctcttcgcct tatagatccg gcttttctat ggacagaatc acatctgtgt cctaaataaa
    24301 ccaaagaaaa ggctggcaca acggccagcc aagattttgc ttttgatttc gctttcttct
    24361 gtagctcccc atcctgcaca gatgacagtc atatggttct tcaccacatg cccagatcca
    24421 aacaggcaga tctgcatgaa tcttcggcgt cgctcccttt tatcggcctt cccctgttcc
    24481 tgcaacatcc agccggttac ttatgattaa cgcaacctct acttttatgt attattctat
    24541 ttatgcctat actatcatta ctctgccgga ttgtcaatct ctacattttc aattttagaa
    24601 attgcgtcca catagccagt cagctcatcc ggaaaattct ttcctgtgag aatcaggctc
    24661 atctcctcgt ctctcaggga gagcagatgt tcaaactcat caagagccag gatatcctga
    24721 tcgagaattc ccagaatctc atcgagaatc agaagatcac attccctggt ggtaagcacc
    24781 tttctggcaa aattcagccc gttctgaatg ttgattttct cctctttttt ctgctcctca
    24841 gaaagctttt cgaaataatc cccctgcttt tcaaaccgga acaccttcat atccggttcc
    24901 aggcacttga gtccctcgga cacctccgcc gacaagctcc ccttgaggaa ctggatcatt
    24961 attacctttt tatgcttggt caccgctaca acgccctttc ccaaagccat ggtggtcttt
    25021 ccaaagccag ggccgcagat gacctggaca cttcccttct ccatatcctg cacctctttg
    25081 tgaaatgtta taaaaactga aacagccgcg ttattttacc acatttttca aagttttgca
    25141 agtttggcag caggctgcgc tttactgcgc ctgatcctcc tgatccggtc cgcactccag
    25201 cttgctgacg gaaacctcgt aagccaccct cttttcgcac tgggtctcgc tcagtttttt
    25261 ggtgtactct ctgctctgaa cacgtcccca tacccgaact ctggatccta cggcaaagcc
    25321 ggaggcgtag cgggcgtttc ttccccatgc gatgcaggga atataatctg attttccgta
    25381 gggcctattg actgccagaa gcagatctgc aatctcacgc cccagaggcg tcttcctgta
    25441 aatggcctcc ttgcatatgt atccgtccag ataaatctgg ttggtcttgg tacagtccgt
    25501 aaactcttcc aggaaattta actctctgac aaaaacggag agtacaaggc ggttcttcac
    25561 tccctcgtgg cagttgtagg agcggaactg tccgatggct tccaccgtct gtcccctgta
    25621 atcctgcttc acgtctaaca ggcgctcgga aaccatcaga ggaatcacgt ccacctgatc
    25681 gcttaaacgg ctggccgcca gacttaccag ataaaagccc tctccaaata cctcatggct
    25741 gaatgtaaat tcagagacta cctctccaat cacgcttacc ttgttgtttt caatcacttt
    25801 ttctgacatt gtacttctcc tcttcctaat tcaaatttca tattcagctt ggctgctaat
    25861 ataatatgta tgtggcgggt tccaaagaaa tctccaaaaa tatctccaaa aatgtctccg
    25921 aaatcagcgc tgctgaatcc gccgaagcct cccgctccgc ctgcaccgcc tccttcaaat
    25981 g
//
LOCUS       DBMDUW010000033        25434 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1326_length_25434_cov_5.342755, whole genome shotgun sequence.
ACCESSION   DBMDUW010000033 DBMDUW010000000
VERSION     DBMDUW010000033.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 25434)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 25434)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25434
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1326_length_25434_cov_5.342755"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..417)
                     /locus_tag="ACZPCR_07525"
     CDS             complement(<1..417)
                     /locus_tag="ACZPCR_07525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2848 family protein"
                     /protein_id="HIR1230763.1"
                     /translation="MKFMVEGKAGERVLDLQYERVFAIGYAGRNMEKTMEHIKELEQE
                     LGVPAPKKIPTIFQCGNYVLTQERNLAFVGNKTCGEVEYVIILSHGKIYIGVGSDHTD
                     RELEAVSVPKAKQICAKPICSRIWDISDWLLKPVSIR"
     gene            complement(455..1243)
                     /locus_tag="ACZPCR_07530"
     CDS             complement(455..1243)
                     /locus_tag="ACZPCR_07530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008397774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen family hydrolase"
                     /protein_id="HIR1230764.1"
                     /translation="MKAAMIQMDMELGKPDENFEKAVRMTEEACALNPDVVILPETWN
                     VGFFPRENLDKLSDRDCSRVKETFSSLSKTYAVNVIAGSVANRKADGNIYNTACVFDR
                     KGNLTAQYDKVHLFSPSGEDDFFQCGDRPCNFELDGIPCSLVICYDIRFPELIRSEML
                     AGSKIQFVVAQWPAVRQLHWDVLNRARAIENQSYVCCTNSVGTAGEVRCAGHSAVYGP
                     MGECLILGGEKEQILIADMEIQEIDRVRSSINVYRDRRPEVYQL"
     gene            complement(1444..2100)
                     /locus_tag="ACZPCR_07535"
     CDS             complement(1444..2100)
                     /locus_tag="ACZPCR_07535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HIR1230765.1"
                     /translation="MVQKQLSYKYQVYNELKKGILTGQYPPGSVMNERKLSEEMGISR
                     TPIREGLQMLARDGWLQMETYKGAVVREFDPHYMWELSRIRYALELSAAEDAVKNMTD
                     QGLERLRQIQAAQREDLSNYNVDEFIRHDREFHSCIYEMSLNRELMKLASNYYDVFRF
                     LGMQAVMGTEERRLTTIEEHQDILEAMEQHNPKAAVQAMKKHMEQTETNIRRHIKIAP
                     "
     gene            2378..2707
                     /locus_tag="ACZPCR_07540"
     CDS             2378..2707
                     /locus_tag="ACZPCR_07540"
                     /inference="COORDINATES: protein motif:HMM:NF015378.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HIR1230766.1"
                     /translation="MKNMKKSVITAASVLMLGSVLLPSHLTALAAPSGAQQSTAVTKD
                     QAKEIAASKAGLSVSDLSFFWMEKEWDDGRLCYEGEFVHKTTEYEFEIDVNTGTVTEW
                     DTESIYD"
     gene            2868..4727
                     /locus_tag="ACZPCR_07545"
     CDS             2868..4727
                     /locus_tag="ACZPCR_07545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003505750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF885 domain-containing protein"
                     /protein_id="HIR1230767.1"
                     /translation="MKAKRQYCCFLLAMLLSVALSSCSRPPAAGTEETGVSLTSPESA
                     SETEASQKESSAVSSSEKSVQAAFDAFTKQIFKDELEGSGLTLHYMLKDPESYGISTA
                     DPKLGECSLEYLEQVSADMEQLSEELHTFDPSLLTADQLFTYRALDDYLETELAARGL
                     ELYTRPVSTTIGTQAQLPILFAEYAFYDRQDVEDYLNLMSQIDSYYKSIAEFEKIRAD
                     AGLAPCDLVLDQIIQSCKDYMIRPENSFLNETFNSKLDSIDGLTEEEKNEYKARHLAV
                     MKEHFIPAYQMLAGELEKLKGRGQNPMGLCGYPDGKRYYEYLAASSTGTGYTVPELKQ
                     QVQVHMSEDLAQVTLLLQNHPELAEASASYSFAQTEPAAILDALKTQAEKDFPALPEA
                     DYTVHQVPKALEASLSPAFYLTAPIDCWQHNVIYINGGSEQTSSEALYTTLAHEGYPG
                     HLYQTVYANQNVRDPLLRLLACGGYTEGWGTYAEIYSYQFDNGLSPELSRLLAHNQAA
                     TLGLYALLDININYEGWSQERTAKFLEELYGITDTQVIEEIYYAVADNPANYLQYYTG
                     YMEMVKMRETAMETLGDRYDPVQFHKFILDMDGASFRVMEPYFKTWLLTCGAQ"
     gene            complement(4830..5498)
                     /locus_tag="ACZPCR_07550"
     CDS             complement(4830..5498)
                     /locus_tag="ACZPCR_07550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HIR1230768.1"
                     /translation="MKMPQRAQLKAEALRYAGLMLGTAVLSFGLYNVHSQSDITEGGV
                     LGLQLLIQNWFGVSPSVIGPVLDLICYLIGWRILGGAFLKNAMVSTLSYGFFYSIHER
                     MGYMLPDLGGSPVLAALVGGLFVGIGVGLVVRAGGATGGDDVLALVLNKLAGVKIEKC
                     YFFTDFVVLVLSLSYIPALKIACSLLTVTISSYIIGKMYQGEENADLKEETNLKQTGR
                     KELV"
     gene            5589..6434
                     /locus_tag="ACZPCR_07555"
     CDS             5589..6434
                     /locus_tag="ACZPCR_07555"
                     /inference="COORDINATES: protein motif:HMM:NF024803.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HIR1230769.1"
                     /translation="MEHRFTAGEIAKLSGLSKQTILFYDKKGILKPDYVDPDNGYRYY
                     SADQLDFLDNISMLKEIGLSLDEIRTFMEQRTRDYAVSRMEEQLASIRQKIKRLQTIE
                     KQLSWKMKTLEDLTSKKEGVFLIRHEKPELLAVEPVSFPRRRKGTDEEDLMAQNIAIK
                     KLMTKAKREHYPYFYQQGALIPLDELQEGHYLRASHVFLPLEKKCAGVLSIVKPPGLY
                     ARYYFTGRYTGSGSAYRLLFSELERLGVLAVSGSYEYCILDSLASQNTDHYVTLIEVE
                     VKKKG"
     gene            complement(6460..7080)
                     /locus_tag="ACZPCR_07560"
     CDS             complement(6460..7080)
                     /locus_tag="ACZPCR_07560"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HIR1230770.1"
                     /translation="MKKLMIALTGILMSVSLAACAPTDTSGQNQDKQAAEGQTVEASI
                     PETEREVVEKLPDADAAPMAQVSMFTVKENRTGLKQSMDAIDSEDGETIDPQLLADKM
                     AENGILEEGTKVLSFSQEGSVISVDLSAMPNQDDVLQQTAVANTLLQNFEASELNLSV
                     NGEKIGTMEFNKGYKNMGSDTSAAEKESAAASGEETAESSQETEAE"
     gene            complement(7108..7563)
                     /locus_tag="ACZPCR_07565"
     CDS             complement(7108..7563)
                     /locus_tag="ACZPCR_07565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002605672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HIR1230771.1"
                     /translation="MKGNTVDNYETFNEVLVRLFRDIMDIEQKAIITPEFRNITNNDM
                     HVIEAIGIGAPKNMSAIARELSVTVGTLTIAMNSLVKKGYVVRARGKEDRRIVYISLS
                     DKGRRAYEHHAEFHRQMIDSIKEELTPQELDILYQALTKLNRWFRELNQ"
     gene            complement(7661..8188)
                     /locus_tag="ACZPCR_07570"
     CDS             complement(7661..8188)
                     /locus_tag="ACZPCR_07570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002605673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein"
                     /protein_id="HIR1230772.1"
                     /translation="MKAILYLSDFLVPAVLFYIIGFGVLSRRPVFDDFIRGAQEGMKT
                     VAGILPTLIGLMTAVGVLRASGFLEFLSEILKAPAGFLRIPGELIPLILVRLVSSSAA
                     TGLLLDIFRTHGPDSLLGMTASIMESCTETVFYTMSVYFMTAKVTKTRWTLAGAAIST
                     AAGIGASILIAGFLT"
     gene            8540..8905
                     /locus_tag="ACZPCR_07575"
     CDS             8540..8905
                     /locus_tag="ACZPCR_07575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004614860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HIR1230773.1"
                     /translation="MSVLFAEYPKCTTCQKAKKWLDAAGVSYEDRHIKEQNPSAEELK
                     KWHQMSGLPLKKFFNTSGLLYKSMGLKDKLPGMSEEEQYALLATDGMLVKRPIVVGDD
                     FVLVGFKEADWEKQLAGQQ"
     gene            complement(9162..10253)
                     /locus_tag="ACZPCR_07580"
     CDS             complement(9162..10253)
                     /locus_tag="ACZPCR_07580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002577106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative NPN-dependent ornithine cyclodeaminase"
                     /protein_id="HIR1230774.1"
                     /translation="MGFELKKYTAPDFTKEPFVSAPDAVLAPAPKDRTAPENYHATTI
                     FPEYFKVNGTWLLAEESRMDCVAVYENGKIAVREFRTLKQGDLVFVGRTEEAEEGIFV
                     WTHGFEEPGTQSKEAFSFRQGRSRETAFSKDYDHIYDLLKHEKDHGYVVWVMGPACAF
                     DSDSREAFSKLVMNGYVDALLAGNALATHDLEGAYRKTALGQDIYTQESFPGGHYNHI
                     DTINRVRYHGSIPEFIEKEHIDNGIMYSCVKKGVPFVLTGSIRDDGPLPEVYADVYEG
                     QSSMRECVKKATTVICMATTLHSIATGNMTPSFRVMPDGTIRQIYFYSVDISEFAVNK
                     LGDRGSLSAKSIVTNVQDFVVNVSKGLGL"
     gene            complement(10308..10937)
                     /locus_tag="ACZPCR_07585"
     CDS             complement(10308..10937)
                     /locus_tag="ACZPCR_07585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002605467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition domain-containing
                     protein"
                     /protein_id="HIR1230775.1"
                     /translation="MLNLLWAVMMAAGLIWGAFHGTLGEVTNGALEAAREAVTLGITM
                     LGVMSFWTGILEIGRKSGLMEALAGKMYPILHMLFPRIPRDHPALESICANVTANLLG
                     LGWAATPAGLKAMGDLKALEEERRRQRDVRAVKEGTANDEMCAFLIINISSLQLIPMT
                     MIAYRAQYGSANPAAVTGPALLATSASTLAAVVFCAVKMRGTGTRENQV"
     gene            complement(10994..12094)
                     /locus_tag="ACZPCR_07590"
     CDS             complement(10994..12094)
                     /locus_tag="ACZPCR_07590"
                     /EC_number="1.13.12.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016703 - oxidoreductase activity, acting
                     on single donors with incorporation of molecular oxygen,
                     incorporation of one atom of oxygen (internal
                     monooxygenases or internal mixed function oxidases)
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent flavin oxidoreductase"
                     /protein_id="HIR1230776.1"
                     /translation="MNRFKPLNIGNLTASLPIIQGGMGVGISLSSLAGAVAKAGGVGI
                     ISTAQIGFRDPDFYKNSQEANLKAMETELKKAREIAPDGILGFNIMVATKNYVEYVKT
                     AVKIGADIIISGAGLPVNLPEYVKGTATKIAPIVSTVKSAKVICKLWDRNYKTAPDLV
                     VVEGPLAGGHLGFSREQLTELGADTDQVSKTYHKAEYEEEVKGIIALVKAYGEKYGKE
                     IPVVTAGGVYTHEDMRHCIEDLGADGVQVGTRFVTTEECDAPLVYKQAYINAKEEDIV
                     ITKSPVGMPGRAIMNPFLKKMTAEGEKVTRCFRCLEHCDPANIPYCITQALINAAQGD
                     EDRALIFCGSNACRAEKIETVEEVMRDLCCGA"
     gene            complement(12139..14037)
                     /locus_tag="ACZPCR_07595"
     CDS             complement(12139..14037)
                     /locus_tag="ACZPCR_07595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006783103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit"
                     /protein_id="HIR1230777.1"
                     /translation="MLKDMFKKTYTLIDTKHKKVSEEREGAVNEGQPNIPQGLWRKCN
                     KCGRPIYTEDVRNNYYICPKCDGYFRVHAYRRIEMTIDSGSFEEWDREMEFINPLNFP
                     GYEKKIQAVQEKTNLNEAVVTGWGTIHGQKTAIAVCDSRFIMSSMSHNVGEKIARAVE
                     RATALRLPVIIFACSGGARMQEGLVSLMQMEKTSAALKRHSDAGLLYISVLTDPTTGG
                     VTASFAMLGDIIIAEPKALIGFAGQRVIEQTIRQKLPEGFQRAEFQQDHGFVDLIVER
                     PEMKDTLSYLLRFHSSRNQWNYKGEGRRAQTSESAPETKGCPEGGAARRFPILSNGES
                     LGKEREAELLAAVEKTFERKSAVIKRTSEKEFEDISNRQLSAWDTVLISRSEDRLISS
                     DYIGELFDDFIELHGDRYYGDDGAVIGGIASWHGMPVTVIAQEKGKSTKDNLKRNFGM
                     PNPEGYRKALRLMKQAEKFGRPIICFVDTPGAFPGIEAEERGQGEAIARSLFEASNLT
                     VPALSIVVGEGGSGGALAMAVGNEVWMMENAVYSVLSPEGFAAILWKDGKKASDAAKV
                     MKMTAKDLYELGLIECIIPEPEPATKANKEQICRGLDWRLEEFFLRFREMTREEAVCQ
                     RYDRFRAF"
     gene            complement(14130..15482)
                     /locus_tag="ACZPCR_07600"
     CDS             complement(14130..15482)
                     /locus_tag="ACZPCR_07600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HIR1230778.1"
                     /translation="MFNKILIANRGEIAVRIIRACREMGIKTVAVYSEADRDSLHTLL
                     ADEAICIGPAPSSESYLDMERIISATVAMKADAIHPGFGFLSENARFADLCEKCNIRF
                     IGPSAEIIHRMGNKSEARKTMMEAGVPVVPGSKEPVYTPEEGLKMAENIGFPVMIKAS
                     SGGGGKGMRISRSAEDFEGNFNQAQMESVKGFSDDTMYIEKYIEQPRHIEFQILADEH
                     GHVVHLGERDCSIQRRHQKVIEEAPSAAISPELRKEMGETAVKAARAVGYVNAGTIEF
                     LLDKHKQFYFMEMNTRIQVEHPVTEAVTGIDLIKEQIKIAAGEPLGFSQEDVVIRGHA
                     IECRINAENPEKHFMPSPGTITELHLPGGKGVRIDTHIYNGYKVPPNYDSMLLKLISY
                     DSDREGAMAKMRSALGEIVIEGIDTNVDFQYEILNSEAYQKGSIDTDFIPKEFPSYCR
                     "
     gene            complement(15492..15914)
                     /gene="fabZ"
                     /locus_tag="ACZPCR_07605"
     CDS             complement(15492..15914)
                     /gene="fabZ"
                     /locus_tag="ACZPCR_07605"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008397742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HIR1230779.1"
                     /translation="MLGIKEIQEIIPHRHPFLLIDCVEEIRPGEGAVGYKSVTYNEPF
                     FAGHFPQEPVMPGVLIVEALAQVGAVAILSEEENKGKVAYFGGINSAKFRRKVVPGDR
                     LKLECQIIKRKGPVGIGSATASVDGKVAVSAELTFMIG"
     gene            complement(15940..16446)
                     /gene="accB"
                     /locus_tag="ACZPCR_07610"
     CDS             complement(15940..16446)
                     /gene="accB"
                     /locus_tag="ACZPCR_07610"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003505740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HIR1230780.1"
                     /translation="MEIKDIVTLIEAVSKNNLTSFVLEENGTKLSLKREKERETVVTA
                     VPAPGFAPVSAAPMMSQPAAAFQVSGASEASGAETPAANAESRDIASGNTVSSPLVGT
                     FYASPSPDAEPFVKTGDRVKKGQVLGIIEAMKLMNEIESEYDGVVEAVLVNNEEVVEY
                     GQPLFRIK"
     gene            complement(16463..17701)
                     /gene="fabF"
                     /locus_tag="ACZPCR_07615"
     CDS             complement(16463..17701)
                     /gene="fabF"
                     /locus_tag="ACZPCR_07615"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002605461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HIR1230781.1"
                     /translation="MANRVVITGMGVVSPIGNDVETFWNSLKENKRGFGEITYFDTTD
                     YKVKLAAQVKDFDPKQYMDPKTARRMEPFSQFAVAAAGQALAQSGIDMEKEDPFRVGV
                     SVGSGIGSLGAIEREHKKMLEKGPGRINPLLVPMMICNMAAGNVAIQYGLKGKCINVV
                     TACATGTHSIGEAFRSIQCGEADVMVAGGAEASITGLGVAGFTALTALSTNTDPATCS
                     RPFDKDRDGFVMGEGAGVVVLESLEHAQKRGAVILAELAGYGATCDAYHITSPAEDGS
                     GAAKAMEYAIKDAGITPDQIDYVNAHGTSTHHNDLFETKAIKLALGDHAYKVKVNSTK
                     SMVGHLLGAAGGVELITCVKSVMEDYVHVTSGLSESEPECDLDYTKGEGVHTTVNYAI
                     SNSLGFGGHNASLVVKKFEA"
     gene            complement(17712..18455)
                     /gene="fabG"
                     /locus_tag="ACZPCR_07620"
     CDS             complement(17712..18455)
                     /gene="fabG"
                     /locus_tag="ACZPCR_07620"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008726615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HIR1230782.1"
                     /translation="MLLEGKIALVTGASRGIGRQIALTLAKEGAVVIVNYNGSAAKAE
                     EVVREITEAGGTAEAVQCSVSDYAKTEEMMKDLIARYKRIDILVNNAGITKDNLLMKM
                     NEEEYDAVLDTNLKGTFNCIKHISRQMLKQKGGRIINISSVSGVMGNAGQANYCASKA
                     GVIGLTKSVARELGSRGITVNAIAPGFIDTEMTAVLPEDVKKAMGDQIPMKKFGKTED
                     VANLAAFLASDQAGYITGQVINVDGGMAM"
     gene            complement(18544..19464)
                     /gene="fabD"
                     /locus_tag="ACZPCR_07625"
     CDS             complement(18544..19464)
                     /gene="fabD"
                     /locus_tag="ACZPCR_07625"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002565798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HIR1230783.1"
                     /translation="MSKIAFIFPGQGAQVCGMGQDFYEQTETGRKVFDTASEILGFSM
                     PELCFEKNDRLDITEYTQPAMVTASLAMMKVLMEQTGIKPDAAAGLSLGEYPAMAAAG
                     VMSAEDAIRTVRERGILMQEAVPAGIGAMAAVLAMDAEEIEKVIAPIEGVQIANYNCP
                     GQIVISGKKEAVDEAAEKLKEAGAKRVIPLNVSGPFHSKMLTEAGEKLGKVLDTVEIH
                     KPAIPYAANVTAEYVTEAEDVKPLLERQVSSSVRWEQTMRMMLADGVDTFIEIGPGKT
                     LAGFMKKIDRSVRVINIEKLEDIEKVRELL"
     gene            complement(19564..20487)
                     /gene="fabK"
                     /locus_tag="ACZPCR_07630"
     CDS             complement(19564..20487)
                     /gene="fabK"
                     /locus_tag="ACZPCR_07630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HIR1230784.1"
                     /translation="MKTRVTELLGIECPIIQGGMAWVAEHHLAAAVSEAGGLGLIGGA
                     NAPGEVVREEIRKARELTKKPFGVNVMLMSPHADDVAKVVVEEGIKVVTTGAGNPGKY
                     MEMWKAAGIKVIPVVASVALARMMEKGGADAVIAEGMESGGHIGEATTMTLVPQVADA
                     VSIPVIAAGGIGDGRGIAAAFMLGAEAVQMGTRFVVAKESIVHPGYKERIIKAKDIDS
                     TVTGRTHGHPVRCLRNQMTREYIKLEQEGKSFEELEYLTLGTLRKAVMEGDTVNGTVM
                     AGQIAGMIKKEQTCKEMIDEMMAEAGRLLHW"
     gene            complement(20487..20720)
                     /gene="acpP"
                     /locus_tag="ACZPCR_07635"
     CDS             complement(20487..20720)
                     /gene="acpP"
                     /locus_tag="ACZPCR_07635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008397736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HIR1230785.1"
                     /translation="MLEKMKEIIAEQLSVDAESITEASSFKDDLGADSLDLFELVMAL
                     EDEYSVEIPAEDLQNLLTVGDVMNYLKEKGVEA"
     gene            complement(20861..21823)
                     /locus_tag="ACZPCR_07640"
     CDS             complement(20861..21823)
                     /locus_tag="ACZPCR_07640"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HIR1230786.1"
                     /translation="MTTKIIGIGSYVPDTVVTNQDLMKFLDTDDAWIRERTGICERRV
                     SKDMGTCGLAIEAAKRAIDDAGIDPKEIDLIVLATSSGDRAFPAAAMDVQAAIGAVNA
                     VGFDITAACSGFIFGLHIAHSFFAAGIYKTALIIGAETLSKVVDWTDRGTCILFGDGA
                     GAAVVRASETGIIRTLMGSDGTKGWTLECQARNLGNCVNGIKPELGFMKMDGKEVFKF
                     AVRKVPEIVAQILEDAQMDPEEIKYFVLHQANFRILEAASRRLKVPMDRIPVNIDRYG
                     NTSAASVPILLDELKRDGKLERGDKLVLAGFGSGMTWGATLLEW"
     gene            22134..22829
                     /locus_tag="ACZPCR_07645"
     CDS             22134..22829
                     /locus_tag="ACZPCR_07645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007871169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIR1230787.1"
                     /translation="MQKILVCDDDKQIVEAIDIYLTGEGFQVIKAYDGLEALELLKTN
                     EVNLMIVDVMMPGLDGIRTTLKVRETSSIPIIILSAKSEDSDKILGLNIGADDYITKP
                     FNPLELVARVKSQLRRYTQLGNMNTQTDSRVYKCGGLQINDENKEVFVDGELIKLTPI
                     EYNILLLLVKNAGKVFSIDQIYEEIWNEEAIGADNTVAVHIRHIREKIEINPREPRYL
                     KVVWGVGYKIEKQ"
     gene            22840..25176
                     /locus_tag="ACZPCR_07650"
     CDS             22840..25176
                     /locus_tag="ACZPCR_07650"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1230788.1"
                     /translation="MTIRKLSLYQRKIAACVVHLLFLALAFIGVGIMYMNDNLGVGIT
                     RIHSGSYEETDEFTQYFNEDLSDIFQYMEYHNIFATGGSIDISKEMLQMTFGPNDTRS
                     FSLNDIIKYLKSLGYYLNEDFQCTPVSLDENRKPLKGYVAWSANQPDVYYTSLREGMR
                     YCSLEEISLEILSTLNQYYSTYKRLFDQPCNLHFKIEYLDNESNPKRITSFSNDEELT
                     LDTARNYGRYACLQGNSVFYDTNFKSIDLDTVSALSANNPYSTKTYYLLAALDTNYPA
                     DDAYAANYRHYVRMQNYYFLGFALMAVGGLTAAFSLLYLLSVSGRQEDGDHAVSLTPF
                     DHTSTETGMMIVCLMTAAALFACRYTMVRVLHLTLSEESWDVGEKALYTAVIYLGCLI
                     AAFSLIRRYKAGVIWENSLIRKLGVRLSIFFTGQTFAGQLTVSFIAYLICNTILLLTA
                     AYLYLKWHILSMTLKIMIGVLAALWFCLNLWIFYVMFRRAADRDKIDLAIRHLADGET
                     SYQVDLTQFSGKIRETAENLNNASRGLEMALSEKVKSERLKADLITNVSHDIKTPLTS
                     IINYVDLIKRENIQDEKILRYLDVLEQKSHRLKNLTEDLVEASKASSGNLKLEISRLD
                     FIELIYQTNGEFEEKFASRHLNLITSAPDHTLFIEADGRRLWRVLENLYNNAFKYALE
                     GSRIYVDVAEEDSMAVFTIKNMSSNPLNIKAEELTERFVRGDVARTTEGSGLGLSIAK
                     SLTQLQGGTFEIYIDGDLFKVKVAFPVMRAAKQENLAE"
BASE COUNT         5885 a         7204 c         5687 g         6658 t
ORIGIN      
        1 acggatgctc accggcttca agagccagtc gcttatgtcc catatcctgc tgcaaatggg
       61 ttttgcacag atctgctttg ctttaggaac acttacagcc tccagctcac gatctgtatg
      121 atcgcttcct acgccaatat aaattttacc gtgagacaag ataatcacat actctacctc
      181 tccgcaggtt ttatttccta caaaagccaa atttctctcc tgtgtcagaa cgtaatttcc
      241 gcactgaaaa attgttggaa tttttttagg agccggaacc cccaattcct gttccaattc
      301 tttaatatgc tccattgtct tttccatatt tcttcctgca tagccgatgg cgaatactct
      361 ttcatactgt aaatctaata ccctctctcc tgctttgccc tccaccataa atttcatttg
      421 actcatcctt ctccctctcc tcttttctta ttttttataa ctgatatact tctggccttc
      481 tgtcccggta gacattaata gaagaacgca ctctgtctat ctcctgaatc tccatatcag
      541 ctattaaaat ctgctctttt tctccaccta gaatcaggca ctctcccatc ggaccataaa
      601 ctgccgaatg gcctgcgcat ctcacttccc cagccgttcc aacagaattc gtgcagcata
      661 cataactctg attttcaatt gctctggcac ggttaaggac atcccaatgc agctgtctga
      721 cagccggcca ctgagctaca acaaactgta tctttgagcc agccagcatt tctgaacgaa
      781 ttagctctgg aaaacggata tcatagcaaa tcacaaggct gcatggaatt ccatctaatt
      841 caaaattaca gggacgatct ccacattgaa aaaagtcatc ttcccctgat gggctaaaca
      901 gatgcacctt atcatactgc gctgttaaat ttccctttct gtcaaatacg caggcagtat
      961 tgtaaatgtt tccatctgcc tttctattag ccacgcttcc ggcaatcaca ttcactgcat
     1021 acgttttcga taaagaagaa aatgtttcct tcacacggct gcagtctctg tctgacagct
     1081 tatctaaatt ttctctggga aaaaaaccta cattccacgt ttcaggcaga ataaccacat
     1141 ctggattcaa agcacaggct tcctctgtca tcctaaccgc cttttcaaaa ttttcatccg
     1201 gctttccaag ttccatatcc atttgaatca ttgcagcttt catatcaatt ctcctttata
     1261 ttattcctgg ctctcactac attttcaaac cttaccctca ttttggtatt cggtatttgg
     1321 tatttggtat accatttatg ggattataat actccttttc ttacggcctg tcaatttaca
     1381 cattttacaa aaagttactg aagtatttat gagatattcc taattctcat ttttaaaatt
     1441 ctgctatgga gcaatcttaa tgtgacgtct gatgttggtc tccgtctgtt ccatgtgttt
     1501 tttcatggcc tgaacagcag ctttgggatt atgctgctcc atcgcctcca gaatatcctg
     1561 atgttcctct attgttgtta aacgccgctc ttccgttccc attactgcct gcattcctaa
     1621 aaaacgaaac acatcatagt aattgctggc cagcttcatc agttctctgt ttaagctcat
     1681 ttcgtaaata caggaatgga attctctgtc atgtcttata aattcatcta cattataatt
     1741 tgagagatcc tctctttgag ccgcttgaat ctggcgaagt ctctctaacc cctgatccgt
     1801 catatttttt actgcatcct cagctgctga cagctctaat gcatatctga tcctgctcag
     1861 ctcccacata tagtgtgggt caaactctct aacgactgct cctttgtagg tttccatctg
     1921 gagccatcca tctctggcca gcatctgcag cccttcacga atcggcgtgc ggctaatccc
     1981 catttcttct gaaagctttc tctcattcat cacgcttccc ggcggatact gaccagtaag
     2041 aatccctttt tttagttcat tatatacctg atatttatat gataactgtt tctgtaccat
     2101 aaagcagccg ctcctctcac ccgaattaca gtttccacca tatatttttc aagccacaaa
     2161 aaactttccc taattaacta gaaaactgta tctgttttcg taacgtaaca cacaggccta
     2221 gaatttgtca aggattattt cgccttcagt ggtgactagc atatgtctga accagggtca
     2281 aagatttcct cccattttaa ttttccttta atctttctcc tgtatgataa aaccatagca
     2341 tcagtataca aaaacagata ccacaaggag gtttcctatg aaaaatatga aaaaatcagt
     2401 gattacagcc gcatccgttc ttatgcttgg aagtgttctt cttccgtctc atctcaccgc
     2461 tctggccgct ccttccggcg cacagcagtc cactgcagtg acaaaagatc aggcgaaaga
     2521 aatcgcagcc tccaaagcag gtctttccgt ttccgatctg tcttttttct ggatggaaaa
     2581 ggaatgggac gacggacgtc tctgctatga gggggaattc gtccacaaaa cgacagaata
     2641 tgaatttgag atcgatgtga atacaggaac cgttacagag tgggatacgg aaagtattta
     2701 cgattaatgc ttttgtaatg actccaacgc agaaacaggc agttttggaa agggccgggt
     2761 aaaatccccg gctctttcct ttgcgcgcgc gccttcctcc agtatattca tgagttgtaa
     2821 ttggccataa tataaattat aatgaaacaa aatggaggta tatgaacatg aaagcgaaac
     2881 gacaatactg ctgcttcctg ctggctatgc tcctctctgt cgcgctcagt tcctgctcaa
     2941 ggcccccagc cgcaggaaca gaagaaaccg gtgtctcact gacatcaccg gagtctgcgt
     3001 cagaaactga agcatctcag aaggaaagct ctgccgtctc ttcctctgaa aaatctgtac
     3061 aggcggcatt tgatgcgttt acaaagcaga tatttaaaga cgagctggag ggatccggcc
     3121 tgactctcca ctatatgtta aaggatccgg aaagctacgg catttccaca gctgatccaa
     3181 agcttgggga atgctctctg gaatatctgg aacaggtttc cgctgatatg gagcagctgt
     3241 ctgaggagct gcataccttt gatccctctc tgctgacagc ggatcagctg ttcacctacc
     3301 gcgctcttga cgactacctg gaaacagagc tggcggccag gggactggag ctctacacgc
     3361 gccctgtatc caccaccatc ggaactcagg cccagctccc cattctgttt gcagaatatg
     3421 ctttttatga caggcaggat gtggaggatt atctgaatct gatgtcccag attgactcct
     3481 actacaagag cattgccgaa tttgagaaga tccgggccga cgccggactt gcgccctgcg
     3541 atctggtatt ggatcagatc atccagtcct gtaaggacta catgatccgg cctgaaaaca
     3601 gctttttaaa tgaaaccttt aacagcaagc tggactccat agacgggctg accgaggagg
     3661 aaaagaacga gtacaaagca cgccatctgg ccgttatgaa ggagcacttt attcccgctt
     3721 accagatgct ggccggagag cttgagaagc tgaagggacg cggccaaaac ccgatgggac
     3781 tgtgcggata cccggatgga aaacgatact atgagtatct tgcagcctcc tccacaggaa
     3841 caggctatac ggtgcctgag ctgaaacagc aggtgcaggt acatatgagc gaggatctgg
     3901 ctcaggtgac gctgctcctt cagaatcatc cggagcttgc ggaggcgtcg gccagctatt
     3961 cctttgccca gacggaacct gctgccatct tagacgccct gaaaacccag gccgaaaagg
     4021 attttccggc tcttccagaa gcggattaca ccgttcacca ggtccccaag gcgttagaag
     4081 cctccttaag ccccgctttc tatctgacag ctcccattga ctgctggcag cacaatgtca
     4141 tttatattaa cggaggatct gagcagacct cttccgaggc gctgtacacc actctggccc
     4201 acgaaggcta cccgggccac ctttaccaga ctgtctacgc caaccagaat gtgcgggatc
     4261 ctcttctgag acttctggcc tgcggcggct acacagaagg ctggggaacc tacgcggaaa
     4321 tctattccta tcagtttgac aacgggcttt ctccggagct ttccaggctg ttagcccaca
     4381 atcaggccgc cactctggga ctctatgcgc tgctggatat taacattaac tacgaagggt
     4441 ggagccagga gcggaccgct aaattcctgg aggagcttta cggcatcacc gacacccagg
     4501 taatagaaga aatctactat gccgttgccg acaatccagc caattatctg cagtattaca
     4561 caggatatat ggaaatggta aaaatgcggg aaacggccat ggaaaccctg ggggatcgtt
     4621 acgatcccgt ccagttccac aaatttattc tggatatgga cggagcctcc ttccgcgtca
     4681 tggaacccta ctttaaaaca tggctgctca cctgcggagc gcagtaaagc ggcaaacgga
     4741 ccgtaaaaat ccggggaatt ttctttgttt ttcaaaaacc tcagaaaatt ccccggattc
     4801 tttctcctat catctttttg cctgcgtttc tacaccagct cttttcttcc agtctgtttt
     4861 aaattggtct cctctttcaa atctgcgttc tcttctccct ggtacatttt tccgataata
     4921 taggaagaaa tggtaactgt cagcagggag catgcaattt taagcgcagg aatatagctc
     4981 agcgagagca ccagcactac aaaatctgtg aaaaaatagc acttctcaat ctttactccg
     5041 gccagcttat tgagcaccag ggccagcacg tcgtcgcctc ctgtggctcc tccggccctg
     5101 accacaagcc ctacgccgat tcccacgaaa aggcctccca caagggctgc aagcaccgga
     5161 ctgccgccca ggtccggaag catatacccc attctctcat ggatcgagta aaagaaaccg
     5221 tagctgagcg tggataccat ggcgtttttc agaaaagcgc ctcctaaaat ccgccagcca
     5281 atgagatagc agatcaggtc gagaaccggg ccaatgacgc tgggggaaac gccgaaccag
     5341 ttctgtatta acagctgcag tcccagcacg ccgccctctg taatatccga ctggctgtgt
     5401 acgttataaa gtccaaatga caaaaccgct gttccaagca tcagccctgc atagcgaagt
     5461 gcttccgcct tcaactgtgc cctctgcggc attttcatag ataacaactc cttttctgtg
     5521 atttcttgac ataaattagt ataaaggata tagttactat actgtcaagc agaaaggaac
     5581 cgattaaaat ggagcatcgt ttcacagccg gggagatagc taagctgtca ggcctctcca
     5641 aacagacgat tcttttttat gataaaaaag ggattttgaa accggactat gtggatcctg
     5701 acaacggata ccggtactac agtgcggacc agctggattt tctcgacaat atttccatgc
     5761 tgaaggaaat cggcctgtcc ttagacgaaa tccgcacctt tatggaacag cggaccagag
     5821 actacgccgt ttcccgcatg gaggaacagc tggcaagcat ccgccagaaa ataaaacggc
     5881 tgcagaccat tgaaaagcag ctatcctgga aaatgaaaac gctggaagat ctgacctcga
     5941 aaaaagaggg agttttcctg atccgccatg aaaagccgga acttctggcc gtggagccgg
     6001 tctcctttcc caggcggaga aaaggcacgg acgaggagga tctcatggcc cagaatattg
     6061 ccatcaaaaa gctgatgaca aaggccaagc gggaacatta tccctatttc taccagcagg
     6121 gagcgttgat tcctctggac gagctacagg aaggccatta cctgcgggcg tcccatgtat
     6181 ttcttccgct ggagaaaaaa tgtgccggcg ttttgtccat agtcaaaccg ccgggactct
     6241 acgcccgcta ttactttacg ggccgctata cgggaagcgg aagcgcctac cgccttctct
     6301 tctctgagct tgagcggctg ggcgttttgg ctgtgtccgg ctcctatgaa tactgtattc
     6361 tggacagcct ggcttcccag aatacggatc actatgtcac gttaattgag gtggaagtaa
     6421 aaaagaaggg gtgatattcc ccttctctcc tggtttctgc tattctgcct ctgtttcctg
     6481 agaactttct gctgtctctt cgccgcttgc tgccgcgctc tctttctctg ctgcggaagt
     6541 atcacttccc atgttcttgt agcccttatt aaactccatg gttccgatct tttctccatt
     6601 tacagacagg ttcagctcag aagcctcaaa attctgaagc agtgtgttgg caaccgccgt
     6661 ctgctgcaga acgtcgtcct gattcggcat agcggaaagg tctacgctga tcacagagcc
     6721 ttcctgggaa aagcttaaca ccttggttcc ctcctcaaga attccattct cagccatctt
     6781 atctgccaga agctgcggat caatcgtttc tccatcctca gagtcgatgg cgtccatgct
     6841 ctgcttcagt ccagttctat tctccttaac agtaaacatg ctgacctgtg ccatcggagc
     6901 cgcatctgcg tccggaagct tctccaccac ttcccgctct gtctccggaa tggaagcctc
     6961 cacggtctgt ccctctgctg cctgtttatc ctgattctgg ccggatgtgt ctgtaggcgc
     7021 gcaggctgcc agcgatacgc tcatcaaaat tccagttaaa gcaatcatta attttttcat
     7081 cgtgttctcc tctttcattc attgatttta ttgatttaat tccctgaacc agcggttcag
     7141 cttggtaagc gcctgataaa gaatgtccag ctcctgaggc gtcagctcct cttttatgct
     7201 gtcaatcatc tgcctgtgaa actctgcgtg atgctcgtaa gccctccggc ccttatctga
     7261 cagggagata tagacgatcc gccgatcttc ctttcccctg gcccgcacca cgtacccctt
     7321 tttcaccaga ctgttcatgg caatcgtgag agtccctact gtgacggaca gctctctggc
     7381 aatcgcggac atatttttcg gcgccccgat tccgatggct tcaatgacat gcatatcatt
     7441 attggtgata ttccgaaact ccggcgttat gatagccttc tgctcaatat ccataatgtc
     7501 gcggaacagc ctcaccagta cctcattgaa tgtctcgtaa ttgtccacag tgttcccctt
     7561 caccttctaa aaacaaaatt tccccactga ttatacaata aacggacctg gccggcaact
     7621 gttagcgcca ataaaatttt tacggcgccg tcatacgctt ttatgtcaga aaaccggcaa
     7681 tcagaatgct ggctcctatg cctgccgctg tggaaatggc ggctccggcc agagtccagc
     7741 gcgtcttcgt cacctttgcc gtcataaaat acacgctcat ggtatagaac accgtctctg
     7801 tacagctctc cataatagac gccgtcatcc ccagcaggga atccggccca tgagtcctga
     7861 aaatatcgag aagaagcccg gtggcagctg agctggacac gaggcgtacc aggataagag
     7921 gaatcagctc tccgggaatg cggagaaatc ctgctggagc tttcaatatt tctgaaagga
     7981 actccaggaa tcccgatgcc ctcaggactc ccactgccgt cataagaccg atcagcgtgg
     8041 ggagaatccc ggctacggtt ttcatccctt cctgcgcccc cctgataaaa tcgtcgaata
     8101 cgggacgcct ggaaagaact ccgaagccga ttatgtaaaa cagaacagcc ggaacaagaa
     8161 aatctgagag atagagaatt gccttcaaca gcctgctccc tgaatgacct tgcttctatt
     8221 ctatgcaaag atcctccggc agattcttgc ttttctgccc cctgtccgtc tgtttttgtt
     8281 ctatgtctgg tattatacag gtggattgtg taggatctgt gaatgggttc ttgcgaaatc
     8341 ggaaagtttt tataaaattt gtgggaagaa acaggctgtt cagccagtta ttgaggcaaa
     8401 acgcagccag ccgcagagcc tgctgttttt gtctgtttta taacagggct tttctgtatg
     8461 ccgcattgta aaattgtatc tttacagcta taatatgagc taaactatta aaatcaatca
     8521 tttcacggag gaacaaccta tgagcgtatt atttgcagaa tatccgaaat gcactacctg
     8581 ccagaaggcg aagaaatggc tggatgcagc cggcgtctcc tatgaggacc gccacatcaa
     8641 ggaacagaat ccttccgcag aggagcttaa gaaatggcat cagatgagcg gacttccatt
     8701 aaagaagttt ttcaatacca gcggccttct ctataaatct atgggcttaa aggacaagct
     8761 gcccggcatg agcgaggagg aacagtacgc cctcttagct acagacggaa tgctggtaaa
     8821 acgccccatc gtagtgggag acgatttcgt tctggtaggg tttaaggaag ctgactggga
     8881 aaagcagctg gctggacagc agtagaaaat tacccagacc tgcaaatcta tatggcagaa
     8941 aatctatatg acagaatcga caggtaccgt gaccagctgc gttttctgct cgttacgaaa
     9001 gcctcgctat cgtcacagga tacctgtcga ttctgcctgg ctgattagga ggctgtaaaa
     9061 agaacggaag tttttcagcg gctaagctcc tggtggagcg tgaaaacttc cgttcttttt
     9121 tctaacttaa ctgcttctgt cagggctgaa aacccatctc cttacagtcc cagtcccttg
     9181 ctcacattta ccacaaagtc ctgaacgttc gtcacaatgc tcttggcgga aaggcttccc
     9241 cgatctccca gcttattgac tgcaaattct gagatatcca cgctgtagaa ataaatttgg
     9301 cggatggttc cgtccggcat cacacggaag gagggagtca tatttcctgt ggcgatggag
     9361 tggagagtgg tggccatgca gatcacggta gtggcctttt tcacgcactc tctcatggag
     9421 gactgtccct cgtacacatc ggcataaacc tccggcaggg ggccgtcatc ccggatagag
     9481 cctgtcagca caaagggcac gcccttcttc acgcagctgt acatgattcc gttgtcaatg
     9541 tgttccttct caataaactc tggaatggag ccgtgatacc gtacccggtt gatggtatcg
     9601 atatggttgt aatgtccccc tggaaagctc tcctgagtgt aaatatcctg tcccagagcc
     9661 gtcttcctgt aggctccctc taaatcgtgg gtagccaggg cgttgcctgc cagaagggcg
     9721 tccacatagc cgttcataac cagcttggaa aatgcctccc tggagtcgga atcaaaggcg
     9781 caggccggtc ccattaccca gactacatag ccgtgatcct tctcatgctt taacagatcg
     9841 tagatgtgat cgtagtcctt ggagaaggcc gtctccctgg atctgccctg gcggaaggaa
     9901 aaagcctcct tagactgagt tcccggctcc tcaaaaccgt gggtccagac gaaaattccc
     9961 tcttccgcct cctctgtcct tcccacaaag acaagatcgc cctgttttaa cgtccgaaac
    10021 tcccgcactg ctatttttcc gttttcatag acagccacgc agtccatccg gctctcctcc
    10081 gccagaagcc atgttccgtt taccttaaaa tactccggga aaatggtggt agcgtgatag
    10141 ttttccggcg cggtcctgtc cttcggcgct ggagccagca cagcgtccgg cgctgagaca
    10201 aacggttcct ttgtaaaatc cggcgcagta tacttcttta actcaaatcc catagcagct
    10261 tctcctctct tcgtatgtct taccataccg ttctgcgtat agtttcatta tacctgattt
    10321 tccctggttc cggtacccct cattttcaca gcgcagaata caacggccgc cagagtgctc
    10381 gcgctggtgg ccagaagcgc cggacctgtc actgccgccg gatttgcgga tccgtactgg
    10441 gcccggtagg cgatcatggt catgggaatc agctgaagag aagaaatatt gataatgaga
    10501 aacgcgcaca tttcgtcatt ggccgtcccc tccttcactg cgcggacgtc tcgttgtctg
    10561 cgccgctcct cctccagcgc cttcagatct cccatggcct tcagccccgc cggggtggcg
    10621 gcccagccca ggcccagaag attggccgtc acgttggcgc agatggactc cagggccggg
    10681 tggtctctgg ggatacgcgg aaacagcata tgaagaatgg ggtacatttt ccccgccagc
    10741 gcctccatca ggcctgattt tctcccgatt tccaggattc ccgtccagaa ggacatgact
    10801 cccagcatgg tgatccccag cgtcaccgcc tccctggccg cctccaaagc gccgtttgtc
    10861 acctccccaa gggttccgtg aaacgctccc catatgagtc ctgccgccat catcacagcc
    10921 cacaaaagat tcaacaaaaa aatcccacct ttctggcaaa ctttatgccg gaaaggcggg
    10981 aaatagaact gctctaagcg ccgcagcaga ggtctctcat aacctcctcc accgtctcga
    11041 ttttctcagc ccggcaggcg ttgctgccgc agaagatcag ggcgcggtcc tcgtccccct
    11101 gagccgcgtt gatcagggcc tgtgtaatgc agtagggaat attcgccgga tcgcagtgct
    11161 ccagacatct gaaacacctg gtcaccttct ctccctctgc cgtcatcttt ttcaggaatg
    11221 gattcataat cgcccgtccc ggcatcccca ccggactctt ggtaattacg atatcctcct
    11281 ctttagcgtt aatatacgcc tgtttataga ctaacggcgc gtcgcactcc tctgtggtca
    11341 caaatctggt tcctacctgg actccgtccg ctcccagatc ctcgatgcag tggcgcatat
    11401 cctcatgagt gtagacgcca cctgccgtta ccacaggaat ctccttgccg tatttttccc
    11461 catacgcttt taccagagca atgattccct ttacttcttc ctcgtattca gctttatggt
    11521 aggtctttga cacctggtct gtgtctgctc ccagctctgt cagctgctcc ctggaaaagc
    11581 ccagatggcc tcctgccagc ggtccctcca ccactaccag atccggcgca gttttataat
    11641 ttctgtccca gagcttacag attaccttag cggactttac ggtggacaca atcggagcaa
    11701 tcttggtcgc cgttcccttc acgtactccg gcagattgac cggaaggccc gcgccggaaa
    11761 taataatatc cgctccgatt ttaacggctg tctttacgta ttccacataa ttttttgtag
    11821 ccaccataat attaaagcct aaaattccgt ccggcgcaat ctctctggcc tttttaagct
    11881 ctgtctccat ggcctttaaa ttggcctcct gggaattttt gtaaaagtcc ggatccctga
    11941 atccgatctg ggcggtggag atgattccca ctccccctgc ctttgccaca gctcctgcca
    12001 gggatgaaag gctgatgcca acccccatgc ctccctggat aattggaagg ctggctgtca
    12061 gatttcctat attcagcggt ttaaatcgat tcatcctcat tctcctactc tttatgatgt
    12121 tggggccaga cgacctgact aaaaggcgcg gaatctgtca tagcgctgac aaaccgcttc
    12181 ctcccttgtc atctctctga aacgcaggaa aaactcttcc agtctccagt ccagtccgcg
    12241 gcagatctgt tccttattgg ccttggtagc cggctctggc tcaggaataa tgcactcgat
    12301 aagccccagc tcgtaaagat cctttgcagt catcttcatt accttggccg cgtcgcttgc
    12361 cttctttccg tccttccaga ggatagccgc gaagccctcc ggagaaagca cggagtacac
    12421 ggcgttctcc atcatccaga cctcgttgcc cacagccatg gccagagcgc ctccgctgcc
    12481 gccctctcct acgacgatgg aaagagccgg aactgtcagg ttggaggcct caaacaggct
    12541 tctggcaatg gcctcgccct gtcctctctc ctccgcctca atgccaggga acgccccagg
    12601 cgtatccacg aagcagataa taggccgtcc gaacttctct gcctgcttca tcagcctcag
    12661 agcctttctg tagccctccg gattcggcat tccgaagttt ctcttcaggt tgtccttggt
    12721 gctcttgccc ttctcctggg caatcactgt cacaggcatc ccatgccagg aggcgattcc
    12781 tccgataacg gccccgtcgt ccccataata cctgtctccg tgaagctcga tgaaatcgtc
    12841 aaacagctct ccgatatagt cgctggaaat cagcctgtcc tcgcttctgg agatgagaac
    12901 cgtatcccag gcgctcagct ggcggttgga aatatcctcg aactccttct cagaggtccg
    12961 cttaatcaca gcgctctttc tctcaaaggt cttctccaca gcggccagaa gctctgcctc
    13021 cctctctttt ccaagggact ccccattgga taaaatcgga aatctgcggg ctgcgccgcc
    13081 ttccggacag cccttcgtct ccggagcgct ctccgacgtc tgggccctgc gtccctcgcc
    13141 cttgtagttc cactgatttc tgctggaatg gaaccgcaga agataggaca gagtgtcctt
    13201 catctccggg cgctccacaa tcagatccac aaagccgtga tcctgctgga actccgctct
    13261 ctggaagccc tcaggaagct tctggcggat ggtctgctcg attaccctct gtccggcaaa
    13321 tcctatcagc gccttaggct ccgcgatgat aatatctccc agcatggcga agctggccgt
    13381 cacgcctccc gtggtgggat ccgtcaggac gctgatatat aaaagtcccg cgtcgctgtg
    13441 gcgtttcaag gcggcggagg tcttctccat ctgcatcagg gagacaagtc cctcctgcat
    13501 tctggctcct ccggagcagg cgaagataat caccggaagc cttaaagccg tggccctctc
    13561 cacagccctg gcaatcttct cccccacgtt gtggctcata ctgctcataa taaaacggga
    13621 atcgcagaca gcgatggccg tcttctggcc gtgaatcgtt ccccatcctg tcacgaccgc
    13681 ctcattcaga ttcgtctttt cctgaactgc ctgaatcttt ttctcatatc cagggaaatt
    13741 taagggattg ataaactcca tctccctgtc ccactcttca aaggaaccgc tgtcaatggt
    13801 catctcgatt cttctgtagg cgtggacgcg gaagtagccg tcgcacttgg gacagatgta
    13861 atagttattt ctcacatcct ccgtgtaaat cggacggccg cacttgttgc acttgcgcca
    13921 gaggccctga gggatgttgg gctgcccctc gtttacagcc ccctctctct cctcagaaac
    13981 ctttttatgt tttgtatcaa tcaaggtata tgtcttttta aacatatctt tcagcatata
    14041 acactctccc tttccccgaa tcctcgcctc tgctcagact gtgccggacg cttaagccca
    14101 gacagaagca tttccgtcaa aagcctcccc tacctgcagt aggacgggaa ttccttcgga
    14161 ataaaatccg tgtcaatgct tcccttctgg taagcttcgc tgtttaaaat ctcatactgg
    14221 aagtccacgt ttgtatcgat tccctcaatg acaatctcgc cgagggcgct gcgcatcttg
    14281 gccatggctc cctctctgtc gctgtcgtag gaaatcagct ttaaaagcat ggaatcatag
    14341 ttaggcggaa ccttgtatcc attgtagatg tgggtgtcga ttctgacgcc ctttccgccg
    14401 ggcagatgca gctctgtgat ggttcccgga cttggcatga aatgcttctc cggattctcc
    14461 gcattgattc tgcactcaat ggcgtgcccc cggatgacca cgtcctcctg ggaaaagcca
    14521 agcggctctc ccgccgcgat cttaatctgc tccttaatca ggtcaatgcc tgtcacagcc
    14581 tctgtcacag gatgctccac ctggattctg gtgttcatct ccatgaagta gaactgttta
    14641 tgcttatcta acagaaactc gatggttccc gcatttacat atcctaccgc tctggcggcc
    14701 ttcaccgccg tctcgcccat ctcttttctc agctctgggg agatagccgc tgacggcgcc
    14761 tcctcgatta ccttctgatg gcgtctctga atggagcagt ctctctctcc cagatgcact
    14821 acatggccgt gctcgtccgc caaaatctgg aattcaatat gccttggctg ctcgatgtac
    14881 ttctcgatgt acatggtatc gtcggaaaag cccttcacag actccatctg ggcctggtta
    14941 aaattgccct cgaaatcctc tgcgcttctg gaaattctca tgccctttcc gccgccgcct
    15001 gaggaggcct tgatcataac ggggaaaccg atattctcgg ccattttaag cccctcttcg
    15061 ggagtgtaaa ccggctcctt gcttcccgga accacgggaa ctcccgcttc catcatggtc
    15121 tttctggcct cggacttatt tcccatccgg tgaataatct cagcagacgg gccgataaag
    15181 cggatattgc acttctcgca cagatccgca aagcgggcat tttcagacag gaagccgaat
    15241 cccggatgaa tggcatctgc tttcatcgcc actgtagcgg aaatgatcct ctccatatcc
    15301 agatagcttt cactggaagg agccggacca atgcagatgg cctcgtccgc cagaagcgtg
    15361 tggagagaat cacgatccgc ctctgaatag acagcaacgg ttttgattcc catttcccgg
    15421 caggcccgga taattctcac cgcgatctca ccgcggtttg caattaaaat cttgttaaac
    15481 aaacttgtca cctatccaat cataaatgtc agctcagcag aaactgccac cttgccgtcc
    15541 acagacgccg tggcgctgcc gattcctacc gggccttttc tcttaataat ctggcactcc
    15601 agctttaagc ggtctcccgg gactaccttt cttctgaact tggcgctgtt aattccgccg
    15661 aagtaggcta cctttccctt gttctcctcc tcgctcagga tggctaccgc gcctacctgg
    15721 gccagggctt ccacaatcag gactcccggc ataaccggct cctgagggaa atgacctgca
    15781 aaaaacggct cgttgtaggt cactgattta tatcctaccg ctccctcacc cgggcggatc
    15841 tcctccacac agtcgatgag aagaaacgga tgtctgtgag ggataatctc ctgaatttcc
    15901 ttaattccca gcatagaaat acctttccct ttctccggat tatttaatgc ggaacagcgg
    15961 ctggccgtac tccacaacct cctcgttgtt tacaagtact gcctccacaa cgccgtcata
    16021 ctcgctctca atctcgttca tcagcttcat ggcctcgata atgccgagaa cctgtccctt
    16081 ctttactctg tcgccagtct tcacaaacgg ctctgcgtcc ggagacgggg atgcgtaaaa
    16141 ggtgcccacc agcggggagc ttaccgtatt gccggaagcg atatctctgc tctctgcatt
    16201 cgctgcaggc gtctctgcgc cagaagcctc agaagcgccg gatacctgaa aagccgcagc
    16261 cggctggctc atcatgggag ctgcggaaac cggcgcaaaa ccaggcgctg gaacggctgt
    16321 cacaacggtc tctctctcct tctctctctt taaggagagc ttcgttccgt tctcctccag
    16381 cacaaagctg gtcaggttat tttttgaaac agcctcgatc agcgttacaa tatccttaat
    16441 ttccatctct gcctcctctg aattaagcct cgaatttctt taccacaagg cttgcgttat
    16501 gtccgccaaa acccagggaa ttggaaatcg catagtttac ggttgtgtgg acgccctcgc
    16561 ccttggtgta gtccagatca cactccggct cggactcaga aagaccggag gtcacatgaa
    16621 cataatcctc catgacggac ttcacgcagg tgatcagctc cacgcctccg gcagcgccta
    16681 acagatggcc taccatggat ttggtggaat ttacctttac cttgtaagcg tgatcgccta
    16741 aagccagctt gatggccttt gtctcaaata aatcattgtg gtgggtgctg gttccgtggg
    16801 cgtttacata atcaatctga tccggagtaa ttccggcgtc cttgattgca tactccatgg
    16861 ccttggcagc tccgcttccg tcctctgccg gggaggtgat gtggtaggcg tcgcaggtag
    16921 cgccgtagcc tgccagttct gccaggatca ctgcgcctct cttctgggcg tgctctaagg
    16981 actctaagac aaccactccg gctccctcgc ccatcacaaa accgtctctg tccttgtcaa
    17041 acggacggga acaggtagcc ggatctgtat tggtggaaag ggcagtcagg gccgtaaagc
    17101 ctgccactcc aaggcctgtg atgctggcct ctgcgcctcc ggcaaccata acgtcagcct
    17161 ctccgcactg gatggagcgg aaggcctctc cgatggagtg ggttcctgta gcgcaggctg
    17221 ttaccacgtt aatgcatttg ccctttaagc cgtactggat ggccacgttt cctgccgcca
    17281 tgttgcagat catcatggga accagaagcg ggttaatgcg gcccggtccc ttctcaagca
    17341 tcttcttgtg ctctctctct atagctccaa ggcttccgat tccggatcct acgctgacgc
    17401 ctacgcggaa gggatcctcc ttctccatgt cgatgccgga ctgagccagg gcctgtcctg
    17461 ccgcagccac tgcaaactgg gaaaatggct ccattcttct ggctgtcttc ggatccatgt
    17521 actgctttgg atcgaaatcc ttgacctggg ctgccagctt taccttatag tcggttgtat
    17581 caaaatatgt aatctctccg aagcctctct tgttctcctt cagggaattc caaaatgtct
    17641 ccacatcatt tccgattggg cttacgacgc ccataccggt aatcactact ctgtttgcca
    17701 tatattacct cctacattgc catgccgcca tcaacgttga tgacctggcc tgtgatgtat
    17761 cctgcctgat cggaagctaa aaatgcagcc agattcgcca catcctctgt ctttccgaat
    17821 ttcttcatag gaatctgatc tcccatagcc ttctttacgt cctccgggag aactgccgtc
    17881 atttccgtgt caataaagcc cggagcaatg gcatttaccg taatgccgcg gcttcccagc
    17941 tctctggcca ctgacttggt cagtccgatt acgcccgcct tggacgcgca gtagttggcc
    18001 tgccctgcat ttcccataac gccggaaacg gaggaaatat tgatgatgcg gccccccttc
    18061 tgctttaaca tctgtctgga aatgtgcttg atgcagttaa aggttccctt taagttggtg
    18121 tccagaactg cgtcgtactc ctcctcgttc atcttcatga gcaggttatc cttcgtgatg
    18181 cccgcattgt tcaccagaat gtcgattctc ttatatctgg cgatcaggtc cttcatcatc
    18241 tcttctgtct ttgcgtagtc ggagacgctg cactgaacgg cctcagcggt tccgcctgcc
    18301 tcggtgatct cccttaccac ttcctccgcc tttgcggcag atccattgta atttacgata
    18361 accacggcgc cttccttggc cagtgtcagg gcgatctgac ggccaattcc gcggctcgct
    18421 ccggttacca gtgcaatttt gccttccaat aacatagttt tacaaccttt cctcggaatt
    18481 tcttccggta tgcctgaggg taaaagggac gcggcatact gcttccgcgt ctcccacctg
    18541 agcttacaga agctctctta ccttctcaat atcttccagt ttctctatat taatcacgcg
    18601 aacgcttcta tctatcttct tcataaatcc ggccagagtc tttccaggcc cgatttcaat
    18661 aaatgtatcc actccgtcgg ccagcatcat tctcatagtc tgctcccagc gcacggagga
    18721 agacacctgt ctctcaagca gaggctttac atcttctgcc tctgtcacat actctgccgt
    18781 cacattggca gcgtagggaa tcgccggctt gtgaatctcg acggtgtcga gaacctttcc
    18841 cagcttctct cctgcctctg tcagcatttt agagtggaac ggtccgctga catttaacgg
    18901 gatgacccgc tttgcccctg cttccttcag cttctctgcc gcctcgtcca ctgcctcctt
    18961 ctttccggaa ataacaatct gtcccggaca gttatagttg gcaatctgaa cgccttctat
    19021 cggcgcaatt accttttcaa tctcctctgc atccatcgca agcacagcag ccatagctcc
    19081 gattccggcc ggaactgcct cctgcatcag gattcccctc tctcgtactg tgcggatcgc
    19141 gtcctccgca gacatcacgc ctgccgccgc cattgccgga tattcgccca gactgagtcc
    19201 tgccgccgcg tcgggcttga ttcccgtctg ctccatgaga accttcatca tggcaaggct
    19261 ggctgtgacc atagccggct gtgtgtactc tgtgatgtcc agtctgtcat ttttctcaaa
    19321 gcagagctct ggcatggaaa atccgagaat ctcggacgct gtgtcgaaca cctttcttcc
    19381 tgtctcagtc tgctcgtaga aatcctggcc cataccgcac acctgcgcgc cctggcctgg
    19441 gaaaataaat gcaattttgc tcatagcgcc gctccttttt attcctatgg aaacggcccg
    19501 cctgccgtca ctttctgcac acgggccgca cctctattct ccggcgtcgg gactgacgtc
    19561 cttctaccag tgcagaagcc ttccggcctc tgccatcatt tcgtcgatca tttccttgca
    19621 ggtctgctct ttcttgatca tgcctgcaat ctgtcctgcc atgacggttc cgtttactgt
    19681 atcgccttcc atgacagcct ttctgagagt tccaagagtc agatactcca gctcctcaaa
    19741 ggactttcct tcctgctcca gcttaatgta ctctcttgtc atctggtttc tcaggcatct
    19801 gacaggatgg ccgtgagtcc ttcctgtaac ggtggaatca atatccttcg ccttgatgat
    19861 tctctccttg tagccaggat gcacaatgga ctccttcgcc acaacgaagc gggttcccat
    19921 ctgaaccgcc tcagcgccca gcataaatgc cgccgcgatg ccgcgtccgt ctccgattcc
    19981 gcctgccgcg atgacaggga tggaaactgc gtctgcaacc tgtggaacca gagtcatggt
    20041 ggtcgcctcg ccgatgtgtc cgccggactc cataccctct gcgatcacag cgtcagctcc
    20101 gcccttctcc atcattctgg ccagggcaac ggaagctacc acaggaatta ccttgattcc
    20161 tgctgccttc cacatctcca tgtattttcc agggtttccg gctcctgtgg taacgacctt
    20221 gatcccttcc tcaactacaa ccttcgccac gtcgtcggcg tgagggctca tcagcataac
    20281 gttgacgcca aacggcttct ttgtcagctc tctggctttt ctgatttcct cgcgaaccac
    20341 ctcgccggga gcgttggctc ctccgatcag gcccagtcct cccgcctcag aaacggcggc
    20401 agccaggtga tgctcagcca cccaggccat accgccctgg atgattggac attcaatccc
    20461 taaaagttca gtgactctgg tcttcattat gcctcaacac ctttttcttt taaatagttc
    20521 attacatcac cgactgttaa gaggttctgt aaatcctcag ccgggatctc tacggagtac
    20581 tcatcctcca gagccataac taactcaaat aagtcaaggg agtctgctcc cagatcatcc
    20641 ttaaaggaag aagcctctgt aatggactct gcgtccacgc ttaactgctc tgcgatgatc
    20701 tctttcattt tctctaacat agtttttgtc tcctttgctt tatgggtttt agattttctg
    20761 aaagccgttt cggggccctc ccctacggct gtcatttctt ttattatatt tgattttcag
    20821 gaagttgcaa gaaaaaaatc cccggaatcg cagactgatt ctaccactcc agtaaagtag
    20881 ccccccaggt catgccggat ccaaagcccg caagcaccag cttatcgcct ctttcaagct
    20941 ttccgtccct cttcagttcg tctaagagaa tcggaacaga ggcagccgac gtattgccgt
    21001 agcggtcgat attgaccgga attctgtcca tgggaacctt gagtcttctg gaagctgcct
    21061 ccagaattct gaaattcgcc tggtggagga caaagtattt aatctcctcc ggatccatct
    21121 gggcgtcctc caaaatctgg gccacaatct ccggcacctt gcggactgca aacttgaaga
    21181 cctcttttcc gtccatcttc ataaagccca gctccggctt aatgccgttt acgcagtttc
    21241 caagatttct ggcctggcac tctaaggtcc atcccttggt tccgtcgctt cccatcagag
    21301 tcctgataat tcctgtctcg gacgccctga caaccgcagc tccggctccg tctccgaaca
    21361 ggatgcaggt tccccgatcc gtccagtcca ccaccttgct caaggtctcc gctccgatga
    21421 taagagccgt cttataaatt cctgctgcga aaaagctgtg ggcaatgtga aggccgaaaa
    21481 taaagcctga gcaggccgcc gtaatatcga agcccaccgc gttcacagcc cctatggccg
    21541 cctgcacgtc catggccgcc gccgggaacg ccctgtcgcc ggaagaagtg gccagcacaa
    21601 tcaggtcaat ttccttcgga tcgatgccag cgtcgtcaat ggcccgcttc gccgcctcta
    21661 tggccagccc gcaggttccc atatccttag atacccttct ctcgcagatt cccgtcctct
    21721 cccgaatcca ggcgtcgtct gtatcgagaa acttcataag atcctgattt gtaacaactg
    21781 tatccggcac ataagagccg attccaatga tttttgtagt catgtctgat tcctgctttt
    21841 ctgtctgctt tctttcatta actcagtaaa cgaaattgtt tgatattcaa actattgcta
    21901 gtgtattcta tggcaggttg tttgtcaagg aaaaaagtag tacccatttg ctctggcaga
    21961 aggtataatg aaggcaggaa tcgctctgtg agcgattcct gccgctacgc aaacggagta
    22021 tccgtaggat acggagttcg cggttcctta acctatgatg tttctttatt tttatagtgc
    22081 cagtgtacaa gggacgctat acagtctatc tattaaaata ggagggttac ataatgcaga
    22141 aaattctcgt atgcgacgac gacaagcaga tcgtcgaggc tattgatatc tacttaaccg
    22201 gcgagggctt tcaggtgatc aaggcctacg acggcctgga agctctggag cttttaaaga
    22261 caaatgaggt aaatttaatg attgtggacg tgatgatgcc cggtctggac ggcatccgga
    22321 ccaccctcaa ggtccgtgaa accagcagca taccgatcat cattctgtct gccaagtcag
    22381 aagattccga caagattctg ggactgaaca tcggagcaga cgactatatc acaaagccct
    22441 tcaaccctct ggagctggta gcccgcgtga agtcccagct tcgccgctac acgcagctgg
    22501 gaaatatgaa cacccagaca gacagccgtg tatacaagtg cggcggtctc cagatcaatg
    22561 acgaaaacaa ggaagtattt gtggatgggg aattgatcaa gctgacccct attgagtaca
    22621 acatcctgct tctcctggtt aaaaatgccg gaaaggtatt ttccatcgac cagatctacg
    22681 aggaaatctg gaacgaggag gccatcggcg ccgacaatac ggtggcggtc catatccgcc
    22741 atatccggga aaaaatcgaa atcaatccca gggaaccccg gtatctgaaa gtagtctggg
    22801 gtgtgggcta caaaattgaa aaacagtagg tgacacagta tgacgattcg aaagctttct
    22861 ctgtaccagc ggaaaatcgc tgcctgcgtg gttcatctcc tcttcctggc cctggccttc
    22921 ataggcgtgg gaatcatgta tatgaatgac aacctgggcg taggaattac cagaatccac
    22981 agcggttcct acgaggagac cgatgaattt acccagtatt tcaacgagga tttatctgat
    23041 atcttccagt acatggaata tcacaatatc tttgccacag gcggttccat cgacatctca
    23101 aaggaaatgc ttcagatgac ctttggcccc aacgatacgc gttccttttc gctgaacgat
    23161 attattaaat atctgaaatc cctgggctac tatttaaatg aggatttcca gtgtacgccc
    23221 gtgtcgctgg atgaaaacag aaaaccatta aagggttatg tggcgtggtc tgccaatcag
    23281 cctgacgtat actacacttc tctccgggaa ggaatgcgct actgctccct ggaggaaatt
    23341 tccttagaga ttttaagcac cctgaatcaa tattacagca cctacaaacg gctgtttgac
    23401 cagccctgca accttcattt taaaattgaa tatctggaca atgagtcgaa tcccaagcgg
    23461 atcacctcct tctccaacga tgaggagtta actctggata cggccagaaa ctacggccgg
    23521 tacgcctgcc tgcagggcaa ttccgtgttc tacgatacga attttaaatc cattgacctg
    23581 gataccgtct cggccctgtc tgccaataat ccgtattcta cgaagaccta ttacctgctg
    23641 gccgcactgg ataccaatta cccggctgac gacgcctacg cggccaatta ccggcattat
    23701 gtcagaatgc agaattatta cttcctgggc tttgccctga tggcagtcgg cggtcttacg
    23761 gcggccttct ctcttctgta tcttctgtcc gtttccggca ggcaggaaga tggagaccat
    23821 gctgtgtctc tcactccctt cgaccatacc agcacagaaa ccggcatgat gattgtatgc
    23881 cttatgaccg cagcggctct cttcgcgtgc aggtacacca tggtccgggt acttcacctg
    23941 acgctttcgg aggaatcctg ggacgtgggc gaaaaggcgc tctacacagc cgttatttac
    24001 ctgggatgcc tgatagccgc cttcagcctg atcagacggt acaaagccgg cgttatctgg
    24061 gaaaacagct tgatccggaa gctgggcgtg cgcctgtcca tcttctttac aggacagacc
    24121 tttgccggac agctgaccgt atccttcatc gcctacctga tctgcaatac gattcttctc
    24181 ctgactgcag cctacttata tttaaagtgg catattcttt ctatgacgct taaaattatg
    24241 attggggtgc tggcggctct gtggttctgt ctgaatctgt ggatttttta cgtcatgttc
    24301 cgcagagcgg ctgatcgcga caagattgat ctggctatcc gccatctggc agatggagaa
    24361 acctcctacc aggtagattt gacgcagttt tccggaaaaa tcagagagac tgcggaaaat
    24421 ctcaacaacg ccagcagggg gctggagatg gccctgtcgg aaaaggtgaa aagcgaacgg
    24481 ctgaaagccg atctgatcac aaatgtctcc catgacatta agactccttt gacctctatt
    24541 attaattatg tagatttaat caaaagggaa aatatccagg atgaaaaaat cctgcgttat
    24601 ctggacgtgc tggagcagaa atcccaccgt ctgaaaaatc tgacggagga tctggtggag
    24661 gcttccaaag ccagctccgg gaatctgaag ctggagatca gccgtctgga ctttatcgaa
    24721 ctgatttacc agaccaacgg cgaattcgag gagaaattcg ccagccgcca cctgaacctg
    24781 atcacctccg ctccagatca tacgctcttt atcgaggcag acggacggcg cctgtggcgg
    24841 gtgctggaaa acctctataa taatgccttt aagtatgcgc tggaaggcag ccgcatctat
    24901 gtggacgtag ctgaggaaga ttccatggct gtattcacaa ttaaaaatat gtcctccaat
    24961 cctttgaaca tcaaggcgga ggagctgacc gagcggttcg tccggggaga cgtggccaga
    25021 accaccgaag gaagcggtct gggcctctcc atcgccaaga gcctgactca gctccagggc
    25081 ggaaccttcg aaatctacat tgacggagat ctcttcaagg taaaggtagc gttccctgta
    25141 atgcgcgcag caaaacagga gaatttagca gaataaactc tgccgctcca aaccttgaca
    25201 ttaaaaaagg aagagggtgt cgcaaaatca tcaaattaga tgattgagcg acaccttctt
    25261 cctttttatt ttgagattat gcttttgttt ctgttatagg ccaaagcttc tccgtctgct
    25321 tccttgcttc cgcctcagac agggaaaact gcttcacaag agccacaata acggcttccc
    25381 tggaagcgcc cagatcccgg aaagcgtgaa ttaaggctgc gataccctgg attt
//
LOCUS       DBMDUW010000034        25281 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1334_length_25281_cov_4.802701, whole genome shotgun sequence.
ACCESSION   DBMDUW010000034 DBMDUW010000000
VERSION     DBMDUW010000034.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 25281)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 25281)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25281
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1334_length_25281_cov_4.802701"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..187)
                     /locus_tag="ACZPCR_07655"
     CDS             complement(<1..187)
                     /locus_tag="ACZPCR_07655"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230789.1"
                     /translation="MVRELKETAAQRKIDLLCMTVSVCIYILNKAVFISITEGWINYF
                     CRNHLNDLVCPLFFLGYY"
     gene            complement(301..912)
                     /locus_tag="ACZPCR_07660"
     CDS             complement(301..912)
                     /locus_tag="ACZPCR_07660"
                     /inference="COORDINATES: protein motif:HMM:NF025380.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4230 domain-containing protein"
                     /protein_id="HIR1230790.1"
                     /translation="MLQLKKKKGYLLIAAVIGTAVIAWGAFRSYEKPETPDFSDVDTI
                     CEMATLKCFYHNVAEYEKQPDGLFQYGLFQYGYKKMWMEYDGVIIMGIDASKVKINGP
                     DENNVVQIYVPEARVMNAEPDQDTMGEPIVDTGVFTKITIEEEAKALTDAQNKMLENA
                     EQDTLSLEKARSNAKALLKEYVINIGKLTGQNYTVEWLSEPGK"
     gene            complement(946..1533)
                     /locus_tag="ACZPCR_07665"
     CDS             complement(946..1533)
                     /locus_tag="ACZPCR_07665"
                     /inference="COORDINATES: protein motif:HMM:NF025380.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4230 domain-containing protein"
                     /protein_id="HIR1230791.1"
                     /translation="MDTNENKLAEQKKCSIPKIWGVIAIFIGIAALVLVLLVSQKGEE
                     TIVSSSSLKKAVNISELSTAQFTYNGVVAVYKDEKKKKLKCNIRYNAKAKAGIDMTKI
                     EFDIDEEAKTVKPILPEIQVTAIVDEKSLSFLPEEAKIGLQEALTACEEDAQREAEAS
                     PRLKELAEENLQSIITALTYPLLNREEEPYQIIWN"
     gene            complement(1551..2576)
                     /locus_tag="ACZPCR_07670"
     CDS             complement(1551..2576)
                     /locus_tag="ACZPCR_07670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004080114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230792.1"
                     /translation="MDVKSLKGSAANLAGGITKTAKEVAKRSEKVLKGEELKTNTLQM
                     IKSNTEKAVTGIKKGMDKSSETINKVMDANGDGQVDIEDIIIMGLKIPGIRVEREEFL
                     RNEFKKDFSQEIVEKAVEKNPAAAGITPDIIEKYADETIKLERSCVSGISAALAVPGG
                     FTMAATIPADIVQYYGYMLRAAQKLLYLYGFPQIDITEKGKKFDTETLNILILCLGTM
                     YGVAGANNALKTLAKALGTGVQKQLMKKALTKGTIYPIVKSVSKWFGVRMTKEVFTGF
                     FKHAIPVIGGVIGGGLTYISFKPCCDKLKASLQDTFLSNPDLDVQTVEAEKGLFESFG
                     ILEAEEM"
     gene            complement(2797..4167)
                     /locus_tag="ACZPCR_07675"
     CDS             complement(2797..4167)
                     /locus_tag="ACZPCR_07675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007714427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1230793.1"
                     /translation="MENVSKKSFSMLTDRPGKALLLFAFPLILGNLFQQFYNIMDSVV
                     VGKFVSENALASVGASYAVTNVFIAVAIGGGMGSSVIISQFLGAGRLTKMKTAVSTTL
                     ISFLVISAALGAFGLAFNDRILSLMNVPDNIFADAALYLRIYFWGLPFLFMYNVQASV
                     FNSLGDSRTPLKLLIFSSLLNIVLDLLFVIEFHMAVRGVAVATLIAQGLSAALSFLIL
                     MRKLRGYRQDEEDFRFYDREMAASMTRVALPSILQQSIVQLGILLVQSVVNTFGSSVI
                     AGYSAGTRIESISIVPMLAIGNAMSTFTAQNMGAGNQKRVKEGYRVCYFALAGFAVVL
                     CVLTQLFGSLFISAFLDAEASAEAFSVGMAYAGFLSFFYIFIGLKATTDGLLRGAGDM
                     KVFTAANLANLAIRVFVANYFAPRYGVQFVWYAVPLGWAANYLISFVWYLTGHWSRIR
                     LVEKKG"
     gene            complement(4321..5043)
                     /locus_tag="ACZPCR_07680"
     CDS             complement(4321..5043)
                     /locus_tag="ACZPCR_07680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002573030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HIR1230794.1"
                     /translation="MIEFHNVHKSFGKLEVLKGIDFKIEKGQVVTLIGPSGSGKSTIL
                     RCINLLEKPDSGTVLIEGQDITEKKADIQRIRKDIGMVFQHFNLFPHMTVMENMIYAP
                     VRVNGLSKEEAKKKAMELLALVGLTEKADAYPNKLSGGQKQRIAIARALAMEPKIMLF
                     DEPTSALDPEMVKEVLEVIKGLAHTGITMALVTHEMGFAREVSDRICFIDEGRILEDT
                     TPEAFFSQPSTDRAKAFLDKVL"
     gene            complement(5027..5695)
                     /locus_tag="ACZPCR_07685"
     CDS             complement(5027..5695)
                     /locus_tag="ACZPCR_07685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002573031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HIR1230795.1"
                     /translation="MSLDFSSVWQYWPFLWHGAVLTLQMTFLCLICGFVLGVILSLIK
                     ISKCAPLVWFGRFYTSIFRGTPLLVQLCIVHFGLPQLLGVTFTAVQSGILTFSLNSAA
                     YVSEIFRGGIQAIDKGQYEAAASLGVSYRDMMKDIILPQAIKHVLPSLVNEAVALLKE
                     TSILSYIGAVELLRAADQITVMTYRFFEPYLVIAFIYYVFVMVLSTLAGRLERWVNRS
                     DRVS"
     gene            complement(5779..6666)
                     /locus_tag="ACZPCR_07690"
     CDS             complement(5779..6666)
                     /locus_tag="ACZPCR_07690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding periplasmic protein"
                     /protein_id="HIR1230796.1"
                     /translation="MKKIALTLLTALTVGVLAGCSGNGAPAESTAAGTEAAETTAAAE
                     DAGETTAGAEDGDGEVSADNPFNGKTVKVGCSSTFVPFESIEMDAKGNKTYVGMNIDI
                     VTEVVEKNGGTVEFQDMPFKSLTAAIQAGQIDFCSGGMAPTEERKKTLDFSEIFFYPR
                     NGIVYREGDNYTTLDSLEGKTVAYVFGTNYQQVAESIEGVKAVGIQGSPACIEEVKSK
                     RADACIVDGAGAVEFLKQNTGLELSLLDKNEADCFAIGFPKDSPYYETFNETLKEMME
                     SGELDEIIAEHLSEEFIVD"
     gene            7041..7949
                     /locus_tag="ACZPCR_07695"
     CDS             7041..7949
                     /locus_tag="ACZPCR_07695"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002573033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HIR1230797.1"
                     /translation="MSVFTDGKTNGPGICWPDGKRIAVMVTFDFDAEFLRISRAESKG
                     TSIGFTDFSRGQYGPHTGLLRCLNMLDAHQVKSTFFVPGAVAEKYTEQVRMIHERGHE
                     LACHGYRHESVRGISREEEEAILDKSEAALMAVTGKRPAGHRGPESIIHPFTHELLAE
                     RGYLYSSSMKDCDYAYLWEQDGKELPLVELPNDITMDDFTYYYFTFSDPAVRAMYTNR
                     EVLGNWKAEFDGLAEEGDKIFVLKLHPQMIGRASRIAMVGDFISYMKGHGAWITTCEN
                     VARYVLNQHKLPRSGSAPEHHGKEAL"
     gene            7950..8831
                     /locus_tag="ACZPCR_07700"
     CDS             7950..8831
                     /locus_tag="ACZPCR_07700"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002573034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HIR1230798.1"
                     /translation="MDSSRFDRVFPAQFSGDLKVSWPDGKRIAVMLAFDLDAETMWTT
                     RGDGNADHITNLSRGAYGPVQGVPRILNMLDSFGLKATFFVPGVVADKYPDVVKEIAA
                     RGHEIGFHGYFHEEFSTTTCEQENATMERCEQLIRKLTGQQMVSHRAPGGVIHDYSLR
                     LFVERGYIASSNWRNSDGPFIHELDGVKIPLVEVPKDSIFDDTAYDFYTDSAPERYEL
                     KSPGEMLEIWKEEFDTLADEGRMINFVLHPQFIGRVSRVNMLKDLIGYMLSRGAWIDT
                     NRSVAEWVLKESGMLSK"
     gene            8887..9795
                     /locus_tag="ACZPCR_07705"
     CDS             8887..9795
                     /locus_tag="ACZPCR_07705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015544312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase-like domain-containing protein"
                     /protein_id="HIR1230799.1"
                     /translation="MISSVMTRRFRRRLNQGRKALLLGLLAASLLSVPSLAQVRTPQA
                     SGTTVFSNGSAVIDASNASQGYVMVKYSGGTSRIKVRISKGTEYTYDLNTAGNYEVFP
                     LTEGSGTYTIKVFQQVQGTSYAQVMSQTVTANIGYSQSPFLYPNQFCNFNANSAVVAK
                     AAELTGGIADPLAKVQAVYRYAIDHISYDYQKAASVQSGYLPVPDATLASGKGICFDY
                     AAVMTSMLRSQDIPTKLVIGYTGGTYHAWVSVYLSGQGWVDNIIYFDGTNWRYMDPTF
                     ASSGKGDASVSNYISNQANYQAKFTY"
     gene            9833..10879
                     /locus_tag="ACZPCR_07710"
     CDS             9833..10879
                     /locus_tag="ACZPCR_07710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HIR1230800.1"
                     /translation="MKQSVPFTGLSLSGFCMQISILLKSAVPLYEGLSVMAEDASLPK
                     EKEVLSSMSDKLRMGFPFSQAVAEAECFPAYVTQMTLLGERTGTLDAVMEHLSRFYER
                     EYRMGENLRRAVTYPAIMIIMLLAILFILFTKVMPVFSGVYEQLGTSIPPAAQTAIRF
                     GGILSGGALIFAAVLIAVFAVIRLTSRPGQENSLSARLLTRIKNRSSIARLAALRRFC
                     SVMAMTLHCGMDMAEGCRMAASLVDNASVLPGVKACEKELASGKAFYDSIEPSGLFSG
                     FDLQMIRIGSRAGQLETVMKELEADYDERSSDALDSLIARLEPAIVSVLAVAVGLVLL
                     SVMLPLAGILSSIG"
     gene            10905..11261
                     /locus_tag="ACZPCR_07715"
     CDS             10905..11261
                     /locus_tag="ACZPCR_07715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006779248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230801.1"
                     /translation="MLHVQVQKEKRSLSGYLLSLLLFLAVLFFFLFGVRAMESKSEEE
                     SLASLRNAIQRACVQCYAIEGRYPPSVEYLEEHYGIVIDRDRYHVFYDGWASNVMPDI
                     TVLPAEPDSQEKEGTS"
     gene            11258..11968
                     /locus_tag="ACZPCR_07720"
     CDS             11258..11968
                     /locus_tag="ACZPCR_07720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4860 domain-containing protein"
                     /protein_id="HIR1230802.1"
                     /translation="MTKRAPASGKTGFLFSMLLFFVFLFCSVFTVLIGSRVYENIRER
                     DNDSFYRDTAVSYVVNKIRQADQSGGVTVGETDDGTSFLLLTSQVNGAVYETWIYTMD
                     GVLRELFTPRGSGLSVEDGLEICACPDLSFSLDEPDGKRLLTISQAASSEDSPENTRS
                     VSLLLRSASGEFPLQGYSGITEETLTETEASRDFSYLGGSPEEVPARDFSYLGVPKES
                     TAEAETAETSDGQSGQNE"
     gene            11981..12472
                     /locus_tag="ACZPCR_07725"
     CDS             11981..12472
                     /locus_tag="ACZPCR_07725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230803.1"
                     /translation="MLHTKYTVRNKRPSYAFLMEMLWVCGFFAIAACIFVMAFAKADS
                     MSRKAQDLNEAVMAAEQEMEQTFLSEREGIWSVCLDQAWKPVSEDPDSRLPGTDGPFP
                     EETYAVLRVTSQADGRLLNVSIQVDAHVSESIQETIYTLEGSHMTGREEGDRERNSEN
                     RQN"
     gene            12441..12896
                     /locus_tag="ACZPCR_07730"
     CDS             12441..12896
                     /locus_tag="ACZPCR_07730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230804.1"
                     /translation="MKETAKTGRINIGTASIVLILLILCLAVFSLLSLSDAQASLSFA
                     RRRAESVQAFYQADAKAQAWADSIRGMSVSDALSLGTVPEGASVEASEDSRTVTLTIP
                     LSQGQSLLAEYRLSDGQLISSRIFNSEDYAIDTRLPVWTGPEGAETTAE"
     gene            12932..13993
                     /locus_tag="ACZPCR_07735"
     CDS             12932..13993
                     /locus_tag="ACZPCR_07735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007867002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043107 - type IV pilus-dependent motility
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HIR1230805.1"
                     /translation="MDIKEFFQDAVRKQASDIFLIPGMPLAMKINGRIEPVGEEKVFP
                     AEMDNYIREIYAISGNRDMTRIQEQGDDDFSFSIVGLSRFRASVMKQRGSLAAVIRIV
                     RFDLPNPADIHIPETVLNIASMKKGMVLVTGAAGSGKSTTLACVIDRINQTRNAHVIT
                     LEDPIEYLHHHQKSVVTQREIGHDTASYVDGLRASLRQAPDVILLGEMRDYETIQTAM
                     TAAETGHLLISTLHTTGAANTIDRIIDVFPADGQQQVRVQLAMVLKAVVSQQLVPAVD
                     GSLIPAFEIMFVNEAIRSMIRESKIHQIQNVISTSMAEGMVSLDNSLLKYLQLGLITR
                     ETCVSYSPNPEQMKMRLGV"
     gene            complement(14156..14228)
                     /locus_tag="ACZPCR_07740"
     tRNA            complement(14156..14228)
                     /locus_tag="ACZPCR_07740"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14193..14195),aa:Lys,seq:ctt)
     gene            complement(14274..14346)
                     /locus_tag="ACZPCR_07745"
     tRNA            complement(14274..14346)
                     /locus_tag="ACZPCR_07745"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14311..14313),aa:Lys,seq:ctt)
     gene            complement(14476..14607)
                     /locus_tag="ACZPCR_07750"
     CDS             complement(14476..14607)
                     /locus_tag="ACZPCR_07750"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230806.1"
                     /translation="MKKRLLRALSRATCDKVQLNRTVLLWKKRLEEAEKALGRLEKK"
     gene            complement(14655..15323)
                     /gene="trmB"
                     /locus_tag="ACZPCR_07755"
     CDS             complement(14655..15323)
                     /gene="trmB"
                     /locus_tag="ACZPCR_07755"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006773308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HIR1230807.1"
                     /translation="MRLRHIPGAEEAIEQSPYVIQEPKEMKGKWDSVFENRNPIHIEV
                     GMGKGRFIMELAQRNPQINYIGIERYSTVLLKALQKREQLPVSNICFMCIDAKELGEI
                     FEKGEVEKIYLNFSDPWPKDRHAKRRLTSPQFMAVYDQVLAEDGDVEFKTDNRGLFDY
                     SLESIPEAGWKVKEHTFDLHHSPMAEGNVMTEYEEKFSSRGQAICKLTAVRAAGEEQS
                     GGNK"
     gene            15541..16455
                     /locus_tag="ACZPCR_07760"
     CDS             15541..16455
                     /locus_tag="ACZPCR_07760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0070064 - proline-rich region binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HIR1230808.1"
                     /translation="MSTDNINTSSWERIQKGFQETERLLGQKRYNECMIRARQTLEFM
                     VKCLCERFDIMEASLVDMIDALYEHEIINKTTCEHYHKIRMIGNKAVHEEDNLAYNAG
                     QAYHLLSQEIYTFANDFTGKKKRPVPRSQERERTETSSESHPHSSRSGASHAPSRGSS
                     RTGGPARRRRPRSSGPSIDPGSLLKILIPVAVIIILIFIIRMVHPGEENGVETTATIE
                     VETIAPTLEETSTEEETESAAPAKRYKTGDTLNVRSEPSTSASKLGQLAPGAEVNYIE
                     DYDDTWAKISFEGQEGYVSKEYLELIAD"
     gene            complement(16675..16953)
                     /locus_tag="ACZPCR_07765"
     CDS             complement(16675..16953)
                     /locus_tag="ACZPCR_07765"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230809.1"
                     /translation="MKKTVLFAAAALTAFALTACGSKETATETTAAAVETTAAAEEET
                     TAAAEEETTEAAEEETTVAEEETTEAAEEETEAAEEETTEAVEEETEA"
     gene            complement(16994..17161)
                     /locus_tag="ACZPCR_07770"
     CDS             complement(16994..17161)
                     /locus_tag="ACZPCR_07770"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230810.1"
                     /translation="MEKADEKYDEKANKLLKINKNFFRLLIFEKKTLYYGYAMQEGSG
                     SFLSSDRQEDL"
     gene            complement(17178..17849)
                     /locus_tag="ACZPCR_07775"
     CDS             complement(17178..17849)
                     /locus_tag="ACZPCR_07775"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HIR1230811.1"
                     /translation="MIKAVIFDMDGVIIDSEGKYLEYIYEFAREKRRDIQIEELYGTV
                     GATKRDCWEIVEKAVANGQSWEELRREYHERGIWKRAFEEVDYQAIFRPEVLEVMDEL
                     KAMGIRLAVASSTGLEQVKRILTMNHVWERLETAVSGEMFKRSKPDPEIYLHTAAQLR
                     VDPSQCLAIEDSTVGITAGKAAGMKAAALIDDRFGFDRSLADRELGDLREIPALVRSL
                     MEPEA"
     gene            18110..18805
                     /locus_tag="ACZPCR_07780"
                     /pseudo
     CDS             18110..18805
                     /locus_tag="ACZPCR_07780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572855.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
     gene            18914..20539
                     /locus_tag="ACZPCR_07785"
                     /pseudo
     CDS             18914..20539
                     /locus_tag="ACZPCR_07785"
                     /inference="COORDINATES: protein motif:HMM:NF012970.6"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
     gene            complement(20569..21552)
                     /locus_tag="ACZPCR_07790"
     CDS             complement(20569..21552)
                     /locus_tag="ACZPCR_07790"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006776659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HIR1230812.1"
                     /translation="MGHFIVLDLEWNQSSGGRETSMDRLPFEIIEIGAVKLDENLRII
                     SEFSRLVRPQVYKTLHYKISEVTHLSQEKLEQQGERFEKAMEDFLSWCGTDFRLCTWG
                     SMDLTELQRNVVYHGMELPFGKPLFYYDLQKIYGLIRGDGRRESLDTAVEELGIEQGR
                     PFHRALDDAWYTGLVMGKMDFYSMMEYFSVDYYQTPEIEEEELRLKFPTYAKFVSRTW
                     DTKEELLREKQVTDVMCCKCRRLLKKKIRWFSVNQKQYFCLAVCPEHGYVKGKLRIKR
                     SEDGSVFAVQTVKPTDEAGVELLVHRCEEAKKKRAERAKAKKEMKKRERRG"
     gene            22302..24050
                     /locus_tag="ACZPCR_07795"
     CDS             22302..24050
                     /locus_tag="ACZPCR_07795"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005945513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1230813.1"
                     /translation="MNTLKRFIHYYKPYQALFYLDLICAAVISMIDLLYPQILRSLTN
                     TLFAGDPHLLLKALVPIGIGLFIMYIIQSLCKFYVCYQGHMMGANMERDMRQQLFDHY
                     EKLSFSYYDRNNSGQMMSKLVSDLFDIAEFAHHGPENLFISLIKIVGSFIFLFLISWQ
                     LALPLAFLVVCMLVFSLAQNGRMQTTFMDNRKRIGDVNASLQDTLAGIRVVQSFANEK
                     VEQEKFRNSNHRFLMSKDANYHCMASFMSFNLFFQGMMYLVTLVWGGYLIAKGVLQVT
                     DLAMYALYIGIFISPIQILVELTEMMQKGFSGFRRFLDVIDTEPEIKNSPGAVPLTQV
                     SGDVRYDDVSFSYQEDEPVLSHVSFHIPAGKSVALVGPSGGGKTTICSLLPRFYDVTE
                     GSIFIDGTDIKTLTLESLRSQIGIVQQDVYLFCGSVKENIAYGKPGASMEEIIDAAKK
                     ANIHDFIQSLPDGYDTFVGERGTRLSGGQKQRISIARVFLKNPPILILDEATSALDNE
                     SERHIQKSLEELAKNRTTITIAHRLSTIQNADEIIVINCSGISERGTHQQLLEKNGLY
                     AHYYQMQFEGLLEIEN"
     gene            complement(24370..24531)
                     /locus_tag="ACZPCR_07800"
     CDS             complement(24370..24531)
                     /locus_tag="ACZPCR_07800"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230814.1"
                     /translation="MKYYFGPKKSLRYLEEHEPEVFEIYAAALREPTCAHVQTWIDCL
                     KERFEKGIG"
     gene            complement(24539..24994)
                     /locus_tag="ACZPCR_07805"
     CDS             complement(24539..24994)
                     /locus_tag="ACZPCR_07805"
                     /inference="COORDINATES: protein motif:HMM:NF014021.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HIR1230815.1"
                     /translation="MEKIMEYLKSAYHPIGMAVYGSFANGTNHLNSDFDALLVREEGE
                     ISHDHSLICGIELDVFIYPKSLFQQEYPVEDFVQIWDSRILFDQEDVIKNLKQRVNDY
                     IKTFPAKTRAENEHNLAWCQKMLNRTERKDAEGLYRMYWLLKDSLEIFF"
     gene            25183..25256
                     /locus_tag="ACZPCR_07810"
     tRNA            25183..25256
                     /locus_tag="ACZPCR_07810"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:25217..25219,aa:Arg,seq:cct)
BASE COUNT         6156 a         6960 c         5430 g         6735 t
ORIGIN      
        1 aataatatcc tagaaaaaac aggggacata ccaaatcatt caaatgattt ctgcagaaat
       61 agtttatcca tccttctgtg atactgataa acacagcttt gttcaaaata tatatgcaca
      121 cggaaaccgt catacataac aggtcgattt ttctctgtgc agcagtttct tttaactctc
      181 taaccaaaca gtttttcatt agttaaataa agcaaataat caaaactatt gcaacaatag
      241 ctgcagctgc aataataatc ttagtcatat ttttcttcat cctctgtatc ctctcgttct
      301 ctattttccc ggctcagaga gccattccac cgtataattc tgccctgtta attttccaat
      361 gttaatcacg tactccttta acagcgcttt cgcattgctg cgcgcctttt caaggctaag
      421 cgtatcctgc tctgcatttt ccagcatttt attctgagcg tcggtaagtg ccttagcctc
      481 ctcttcaatc gtaatcttcg taaatactcc tgtatcgaca ataggttcgc ccatagtatc
      541 ctgatctggt tcagcgttca ttactctggc ttccggcaca taaatctgaa ctacattatt
      601 ttcatccggt ccattaatct ttacttttga agcatcgatt cccattatta taacaccatc
      661 gtactccatc cacattttct tatatccata ctggaacaac ccatattgaa acagtccgtc
      721 cggctgtttt tcatattcgg ctacattatg gtaaaagcat ttcagcgtcg ccatttcgca
      781 aatggtatct acatctgaaa aatccggcgt ttcaggcttc tcataagatc gaaacgctcc
      841 ccatgcaata actgcagttc ctataactgc ggctattaat aaataacctt tcttcttttt
      901 taactgaagc ataataaaat ccctttctcc tttgtgccgt atctcctagt tccaaataat
      961 ctgatacggt tcttcttccc tgtttaaaag cggatacgtt aatgctgtga taattgactg
     1021 gagattttct tctgccagtt cctttaatct tggcgacgcc tccgcctccc tctgagcatc
     1081 ctcctcgcag gctgtcaaag cctcctgaag ccctatttta gcttcttctg gaagaaaaga
     1141 aaggcttttt tcgtctacta tagcagtgac ctgtatttct ggaagaatcg gttttaccgt
     1201 ctttgcctcc tcgtcgatgt caaattcaat tttggtcata tctattcctg cttttgcttt
     1261 tgcattgtag cgaatattac attttaattt tttcttcttc tcatccttat agacagcaac
     1321 cacgccgtta tatgtaaact gagctgtaga cagttctgaa atattaactg ccttttttaa
     1381 cgaggacgac gaaacgattg tttcctcacc tttctgactc actagcaata ccagcaccaa
     1441 tgccgctatt cctatgaata ttgcaatcac tccccatatt ttgggaattg aacatttctt
     1501 ttgttctgcc aatttatttt catttgtatc cataatcgtc tccccgtaac ctacatttct
     1561 tctgcttcca gaatcccaaa ggattcaaaa agccccttct ctgcttccac cgtttgaaca
     1621 tcaagatcag gattgcttaa aaaagtgtcc tgcaaagatg cctttaactt atcacagcat
     1681 ggtttaaatg atatatacgt cagccctccc ccaataacac ctccaattac tggaattgca
     1741 tgtttaaaaa atcctgtaaa tacctcttta gtcattctga ctccaaacca ctttgaaaca
     1801 ctttttacaa ttggataaat cgtacctttg gtcaaagctt ttttcatcaa ttgtttctga
     1861 acgcctgtcc ctaaagcttt tgccaaagtc tttaaagcat tattagcccc tgctaccccg
     1921 tacattgtcc ccagacaaag aatcaaaata tttaatgttt ctgtatcaaa cttttttcct
     1981 ttttctgtaa tatcaatttg aggaaatcca tataaataga gtaatttctg ggcggccctc
     2041 agcatatacc catagtattg aacaatatct gccggaattg ttgcagccat agtaaagcct
     2101 cccggcactg ctaatgctgc tgaaattcca gagacgcagc ttctttcaag ttttatcgtt
     2161 tcatccgcat atttttcaat tatatctggc gttattcctg ctgccgccgg attcttttct
     2221 actgcttttt caactatttc ctgtgaaaaa tcttttttaa attcatttct taaaaattct
     2281 tcccgttcca ccctaatccc aggaattttt aatcccataa taatgatatc ttctatatca
     2341 acctgcccat ctccgttcgc atccattacc ttattaatgg tttcagatga cttatccatt
     2401 ccctttttta tcccagttac agccttctct gtattacttt taatcatttg caacgtattt
     2461 gtttttaatt cttcaccttt taaaaccttc tctgatcttt tagccacttc ctttgctgtc
     2521 ttggtaattc ctcctgccaa attggcagca gaacctttta gactttttac atccacaatc
     2581 tttcctccct ataacctgtc cttgtcccta aaacatttat accataccgt atctttacat
     2641 tcaatattca ctattttttt caatatgcta tgcaaaaaat attactttca aatcgaacct
     2701 gcggcaggaa acaaccttcc gctttcttat gcgccaggaa aaattttcgg tgacttcaag
     2761 tggaacaaga aaatttttcc tgacgcatct ctttccttac cccttcttct ccaccagccg
     2821 tatccggctc cagtggcccg tcaggtacca gacaaaggaa atcagatagt ttgcggccca
     2881 gcccagagga acagcgtacc agacaaactg aaccccatag cgcggcgcga aataatttgc
     2941 cacaaagacg cggatagcca gattggccag attagccgca gtaaatacct tcatatcccc
     3001 tgctcctctc agcaggccat ccgtggtggc tttaaggcca ataaaaatat agaagaaaga
     3061 aagaaaacct gcgtaagcca ttcccacaga aaacgcctcc gcgctggcct cagcgtctaa
     3121 aaaggcggaa ataaacaggc ttccaaacag ctgtgttaat acgcagagaa ccacagcaaa
     3181 gcctgccaga gcgaaatagc agacgcggta tccctccttc accctctttt ggtttcccgc
     3241 tcccatattt tgagctgtaa aggtggacat ggcgtttccg atggccagca tgggcacaat
     3301 agaaatggac tcaattctcg ttcccgccga atatccggcg atcacggaag agccgaaggt
     3361 gttgactacc gactgcacca gcagaatccc cagctggaca atggactgct gaagaatgga
     3421 gggaagcgcc accctcgtca tggatgccgc catctctctg tcgtagaacc ggaaatcctc
     3481 ttcatcctgc ctgtatcctc tcagcttcct cataagaata aggaaggaga gcgccgccga
     3541 gagcccctgg gcaatcaggg tcgccacagc cacgcctctc acagccatat gaaactcaat
     3601 gacaaacagc agatccagga caatattcag cagggaggaa aaaatcagca gcttgagagg
     3661 cgtcctggaa tctcccagag agttgaacac cgaggcctgc acgttgtaca tgaacaaaaa
     3721 gggcagtccc cagaaataaa tccgcagata aagagccgca tccgcgaaaa tattgtccgg
     3781 cacgttcatc agactcaaaa tcctgtcgtt aaacgcaagg ccgaaagccc ccagcgccgc
     3841 gctgattacc agaaaggaaa tcagagtcgt ggacacagcc gttttcatct tcgtcagccg
     3901 cccggctccc agaaactggg aaataatcac cgagcttccc atgcctcctc cgatggcaac
     3961 ggcaataaac acattcgtaa ccgcgtagga ggcgcccaca gaagccagcg cgttctcact
     4021 gacaaatttc cccactacga ccgaatccat aatattataa aactgctgga acagatttcc
     4081 caaaatcagg ggaaacgcaa aaagcaaaag agcctttccc gggcgatccg tcagcatact
     4141 gaagcttttc ttactcacat tttccatctt ttctatctca ttccctgtct tttctagttt
     4201 ttatttcctg ttttttattt tttattctct atttcctgtt tcttcttttc tgccctgtca
     4261 ttctctttct gcaagctcaa aaaaagagct gtaaaacagc tccttttcat cgttcccagt
     4321 ttacagtacc ttatctaaga atgccttcgc cctgtctgtg gacggctggg agaaaaatgc
     4381 ctcaggagtc gtatcctcca ggattcttcc ctcgtcgata aagcagatcc tgtctgaaac
     4441 ctctctggca aaacccatct cgtgggtgac aagagccatg gtgattcccg tgtgagccag
     4501 gcccttgata acctccagaa cctccttcac catttccgga tccagggcgc tggtaggctc
     4561 gtcaaacagc ataatcttcg gttccatggc aagcgctctg gcaatggcga ttctctgctt
     4621 ctggccgccg gacagcttat tggggtaagc gtccgccttc tcagtcagtc ccaccagagc
     4681 cagcagctcc atagcctttt tcttcgcttc ctccttggaa agcccgttta cacgcactgg
     4741 cgcgtaaatc atgttctcca taaccgtcat atggggaaac aggttaaagt gctggaatac
     4801 catgccgata tctttcctga ttctctgaat gtcggccttt ttctccgtaa tatcctgtcc
     4861 ctcgatgagc acggttccgc tgtccggctt ctccagcagg tttatgcacc gcagaatcgt
     4921 agattttcct gagccggacg ggccaatcag agtgacgacc tgtcccttct caatcttaaa
     4981 atcaatcccc tttaagacct ccagctttcc aaagctctta tgcacgttat gaaactctat
     5041 cacttctgtt cacccacctt tccagacggc ctgccagcgt ggacagaacc atgacaaaca
     5101 catagtaaat gaaagcgatc accagatacg gctcaaagaa ccggtacgtc ataactgtga
     5161 tctggtctgc cgctcttaaa agctccaccg ctccgatgta ggagagaatc gacgtctcct
     5221 ttaaaagggc taccgcctcg ttgacaaggc tgggaagcac atgcttgatg gcctggggaa
     5281 ggatgatatc cttcatcata tccctgtaac tgacgcccag agacgcggcc gcctcgtact
     5341 gccccttgtc aatggcctga atgcctcctc tgaaaatctc agacacatag gcggctgagt
     5401 tcagggagaa ggttaaaatt cccgactgaa cggctgtaaa cgtcacgccc agcagctgag
     5461 gaagtccaaa atgtacgata cacagctgca ccagcagagg agttcccctg aaaatagagg
     5521 tgtaaaagcg tccgaaccac acaagaggcg cacatttgct gattttaatt aacgataaaa
     5581 ttacacccag cacaaaaccg cagatcaggc acaaaaacgt catctgaagc gtcagaaccg
     5641 ccccgtgcca cagaaacggc cagtactgcc atacgcttga aaagtcaagg ctcatatctg
     5701 ttatcctttc tatctgaatt tttcttgttt tctgcacagc gaacggcagg gcgtaatctc
     5761 cgccctgccg cagtccgctt agtcgacgat aaattcctcg ctcaaatgct ctgcaataat
     5821 ctcgtccagc tctccgctct ccatcatttc ctttaacgtc tcgttaaatg tctcataata
     5881 aggagaatcc tttgggaatc cgattgcaaa gcagtctgcc tcgttcttat ccaacaggct
     5941 taactcaagg cctgtattct gctttaagaa ctccactgcc cccgcgccgt ccacgatgca
     6001 ggcatcggct ctcttactct taacctcctc gatgcaggcc gggcttccct gaattcctac
     6061 tgccttcacg ccctcgatgc tctcggccac ctgctgataa ttggttccga atacatatgc
     6121 aaccgtcttg ccttccagag agtcaagagt tgtataatta tcaccttctc tgtatacgat
     6181 gccgtttctc gggtagaaaa agatttcaga gaaatcaagc gttttctttc tctcctctgt
     6241 cggagccata ccgccgctgc agaaatcaat ctgtcctgcc tgaattgccg ccgttaagct
     6301 cttaaacggc atatcctgga attctacggt tccgccgttt ttctccacaa cctctgtcac
     6361 aatgtcaata ttcattccta catatgtttt atttccctta gcgtccatct cgatggattc
     6421 aaacggcaca aatgtggagg aacagcctac tttgaccgtc tttccgttaa acggattgtc
     6481 cgcagaaacc tctccatccc cgtcttctgc tcccgctgta gtttccccgg cgtcctctgc
     6541 cgctgccgtg gtctctgccg cctctgtgcc tgctgccgta ctctctgccg gagcgccgtt
     6601 tcctgaacat ccggccagca cgccgactgt aagagccgta agtaatgtca atgctatctt
     6661 tttcataatt ttctcctcgt tccattctat ttcttttttt cagtttcttg attaactggt
     6721 tcctatgata gcataaatat acattctatg caattccttt tttattattt tttcattttc
     6781 cgacagcttt cagctttttc cctctcattt ttattccatt ctttccatcc cgtctcctcc
     6841 gtggtataat agaattgttt agcagacttt tttcaatatt ggagcggttc gcaggtagct
     6901 ttcaggtctg tctccctctt ttggggccag gctgtttccg ccttttcgaa tccgtttttt
     6961 cacatatggg gtattttttg acaaaattcc ggtattgatt atatatgcag actcaatcat
     7021 tttttataaa ggaggaacct atgtctgttt ttactgacgg aaaaaccaac ggtcccggca
     7081 tctgctggcc ggacggaaaa cggatcgccg tcatggttac ctttgatttt gacgccgaat
     7141 ttctgaggat ttccagggct gagtcaaagg gtacgtccat cggcttcacc gatttttcca
     7201 gaggccagta cgggccgcac acaggacttt taaggtgtct taacatgctg gacgcgcacc
     7261 aggttaaatc taccttcttc gtacccggcg ctgtggcgga gaaatatacg gagcaggtgc
     7321 gcatgattca cgaacggggc catgagctgg cctgccacgg ctaccgccac gaatccgtcc
     7381 gcggcatttc cagagaggaa gaggaagcta ttcttgacaa aagcgaagcg gctctgatgg
     7441 cggtcacagg aaaacgtccg gcaggacaca gaggcccgga gagcatcatc caccccttca
     7501 cccacgaact gctggcagag cgcggctatc tctacagctc ttccatgaag gactgcgatt
     7561 atgcctatct ctgggagcag gatggaaaag agctgcctct ggtggagctg ccaaacgata
     7621 tcactatgga cgattttacc tattattatt tcaccttcag cgatcctgcc gtccgggcca
     7681 tgtacacaaa ccgggaagtg cttggaaact ggaaggccga atttgacggt ctggcggagg
     7741 agggcgacaa gatctttgtc ttaaaactcc atccccagat gattggccgg gccagccgca
     7801 tcgccatggt gggagacttt atttcctata tgaaaggaca cggcgcctgg attaccacct
     7861 gcgagaacgt ggcccggtac gtcctgaacc agcataagct gccaagaagc ggcagcgcgc
     7921 cagaacatca cggaaaggag gcgctgtaaa tggattccag ccgttttgac agagtatttc
     7981 ccgctcaatt ctccggcgat ctgaaggttt cctggccgga tgggaagcgg attgccgtca
     8041 tgctggcctt tgacctggat gcggagacca tgtggaccac cagaggagac ggaaatgcgg
     8101 accacatcac gaacctgtcc agaggggcct acggtcctgt ccagggcgtg cccagaattt
     8161 taaatatgct agacagcttc ggcctgaagg ctaccttctt cgtgcctggc gtcgtggcgg
     8221 acaaatatcc ggatgtggta aaagaaatcg ccgcaagagg ccatgagatc ggcttccacg
     8281 gctatttcca cgaggaattt tccaccacca cctgcgaaca ggagaacgcc accatggagc
     8341 ggtgcgaaca gctcatcagg aagctgacag gccagcagat ggtcagccac cgggctcccg
     8401 gcggagtgat ccacgactac agcctgcgcc tttttgtgga gcgcggctat atcgcaagct
     8461 ccaactggag aaacagcgac ggtcccttca tccatgagct ggacggggta aaaattcccc
     8521 tggtggaggt tcccaaggat tccatcttcg acgatacggc ctacgacttc tacactgaca
     8581 gcgcgccgga acgctatgag ctgaaatctc ccggagagat gcttgaaatc tggaaggagg
     8641 agttcgacac cctggcagac gagggcagga tgatcaattt tgtgctccat ccccagttta
     8701 tcggccgtgt aagccgcgtc aatatgctca aggatctgat tggatacatg ctgtcccgcg
     8761 gcgcctggat tgacacaaac cggtccgtgg ccgaatgggt tttaaaggaa agcggcatgc
     8821 tttcaaagta ggcttcccag gcagctttaa accgaataaa aatatatgta aacgaggtaa
     8881 taatttatga tttcatctgt aatgacgcgc cggttcagaa gacgtctgaa tcaaggcaga
     8941 aaggctctgc ttttaggcct tctggccgct tctctcctgt ccgtcccctc tcttgcccag
     9001 gtgaggacgc cgcaggcttc cggaacaacg gtcttttcca atggcagcgc cgtcatcgac
     9061 gcctccaacg cctcccaggg ctatgtcatg gtcaagtatt ctggcggaac ctcccgcatc
     9121 aaggtgcgta tttccaaggg aaccgagtac acctacgatc tgaataccgc cggaaactac
     9181 gaggtatttc ctctgacaga gggaagcgga acctacacga tcaaggtatt ccagcaggtt
     9241 cagggcacct cctacgccca ggtgatgagc cagactgtca cggcaaatat cgggtacagc
     9301 cagtccccct tcctgtaccc gaaccagttc tgcaacttta acgcaaactc cgctgttgtg
     9361 gccaaggcgg ctgaactgac aggaggaatc gcagatcctc tggcaaaggt gcaggccgtt
     9421 taccgctatg ccattgacca catttcctac gattatcaga aggccgcctc tgtgcagagc
     9481 ggctacctcc ctgtgcctga cgctactctg gcttctggaa agggcatctg cttcgactat
     9541 gcagctgtga tgacttccat gctccgctct caggacattc ctacgaagct cgtcatcggc
     9601 tacaccggag gcacctacca tgcctgggta agcgtatatc tgtccggcca gggctgggta
     9661 gacaatatta tctacttcga cggaaccaac tggcgctaca tggatcccac cttcgcctcc
     9721 agcggcaagg gcgacgcatc tgtgtccaat tatatttcca accaggccaa ctaccaggct
     9781 aaatttacct attaatattc atgctgaata catattgtga ggaattctga ctatgaaaca
     9841 atccgttccg tttaccggtc tttcactgtc cggtttctgt atgcagattt ccattctgct
     9901 gaaatctgcg gtccctctct acgagggact ttccgtcatg gcggaggacg cctcccttcc
     9961 aaaggaaaaa gaggttctct cctctatgtc tgacaagctg cgtatggggt ttcccttcag
    10021 ccaggctgtc gctgaggctg agtgtttccc tgcctatgta acgcagatga cgcttctcgg
    10081 cgaacgcacg ggaacgctgg acgccgttat ggaacacctg tcccggtttt atgagcggga
    10141 ataccggatg ggagaaaacc tgcgccgcgc cgttacctac ccggctatta tgattatcat
    10201 gctgttagcc atcctgttta ttctgtttac aaaggtaatg cctgtattct ccggcgtcta
    10261 cgagcagctg ggaacctcca ttccccctgc cgcccagacg gctatccggt ttggaggcat
    10321 tttaagcgga ggagccctta ttttcgccgc tgtcctgatc gccgtattcg ccgtgatccg
    10381 gctgaccagc aggccgggcc aggaaaacag cctgtcagcc cgccttttaa cccgaatcaa
    10441 gaaccgttcc agtatcgcca ggctggccgc tctgcgccgt ttctgctccg ttatggccat
    10501 gacgcttcac tgcggcatgg atatggccga gggctgccgc atggccgcct ccctggtgga
    10561 caacgcttct gtcctcccag gcgtaaaggc ctgcgagaaa gagctggcct ccggaaaggc
    10621 cttctacgac tccatcgagc catccggcct gttctccggc tttgatctcc agatgatccg
    10681 catcggaagc agggccggac agctggaaac ggtgatgaag gaactggagg cagattacga
    10741 cgagcgttcc tctgacgctc tcgacagcct gatcgcaagg ctggagcctg ccatcgtatc
    10801 cgtactggca gtcgcggtag gtcttgtgct tctgtccgtc atgctgcccc ttgccggaat
    10861 tctttcctcc atcggctaaa cagtgaacaa acaggaggat ccatatgctg cacgtacaag
    10921 ttcaaaaaga gaagaggagc ttatccgggt atctgttatc cctcctcctc tttctcgctg
    10981 ttttattttt cttcctcttt ggcgtcaggg ccatggagtc caaaagcgag gaggaaagcc
    11041 tggcgtctct caggaacgcc atccagaggg cctgcgtcca gtgctacgcc atcgaggggc
    11101 gctatccgcc cagcgtagaa tacctggagg aacactacgg catcgtcatt gacagagacc
    11161 ggtaccacgt gttctacgac ggctgggcca gcaacgtaat gcctgacatc accgtgcttc
    11221 ctgcagagcc ggacagccag gagaaggagg gaacatcatg acaaagcggg ctccagcttc
    11281 aggaaaaaca ggattcctgt tttccatgct tctgtttttc gtatttctct tctgctccgt
    11341 gtttacagtt ctcataggca gccgcgtcta cgaaaatatc cgggaaaggg acaacgactc
    11401 cttttaccgt gatacggcgg tcagctacgt ggtaaacaaa atccgccagg cagaccagag
    11461 cggaggcgta acggttggag aaaccgacga tggaacctcc ttcctgctcc tcacttccca
    11521 ggtaaacggg gctgtctacg aaacctggat ttacaccatg gacggcgttc tcagggaact
    11581 ttttactccc agaggcagcg gcctgtccgt ggaggacgga ctggaaatct gcgcctgtcc
    11641 cgacctgtcc ttctccttag acgagccgga cggaaaacgt cttttaacca tctcccaggc
    11701 agcttccagc gaagattccc cggagaatac aagaagcgtc tctcttcttc ttcgaagcgc
    11761 ttccggagaa tttcctctcc agggatattc agggataaca gaagagacgc tgacagagac
    11821 ggaagcctcc cgggacttct cctatctggg cggcagcccg gaagaagtcc cggccaggga
    11881 tttttcctat ctgggcgttc cgaaggagag cacggcagag gctgaaacgg cagaaacatc
    11941 agacggccag tccggccaaa atgaataaag gaggagggca atgctgcaca caaaatacac
    12001 agtaagaaac aaacggcctt cctacgcttt tctgatggaa atgctgtggg tctgcggctt
    12061 cttcgccata gccgcctgca ttttcgtcat ggctttcgca aaggccgact ccatgagccg
    12121 gaaggctcag gatttaaacg aggccgttat ggctgcagaa caggaaatgg aacagacctt
    12181 cctctctgag agagagggga tctggagtgt ctgcctggat caggcctgga agcctgtttc
    12241 cgaggatccg gacagccgcc tgcctggtac agacggaccg tttccggagg aaacctacgc
    12301 ggttctgcgc gttaccagcc aggcagacgg cagactttta aacgtgtcca ttcaggtgga
    12361 cgcccacgtt tcagaatcca tccaggaaac catttacacg ctggagggaa gccatatgac
    12421 aggaagagag gagggagatc gtgaaagaaa cagcgaaaac cggcagaatt aatatcggaa
    12481 ccgcctccat tgtcctgatt ctcctgatcc tgtgcctggc cgtattctcc cttttaagcc
    12541 tcagcgacgc ccaggcgtcc ctgtcctttg ccagacggcg tgcagaatcg gtgcaggcct
    12601 tctatcaggc tgacgcgaag gcccaggcct gggctgacag tatccgggga atgagcgttt
    12661 ccgacgccct gtctctggga accgtcccgg aaggcgcgtc tgtggaggcg tcggaggaca
    12721 gccgtaccgt aacgctcacc attcccctgt cccagggaca atccctgctg gccgagtacc
    12781 ggctgtcaga cgggcagctg atctcctccc gcattttcaa cagcgaggac tacgccatcg
    12841 acacgcggct gcctgtatgg acagggccgg agggagcaga aacaacggca gagtaatctg
    12901 cccaagcagc ttttaagcaa agaggttcat tatggatatt aaagaatttt ttcaggacgc
    12961 cgtaagaaaa caggcctctg acattttcct gattccagga atgcctctgg ccatgaaaat
    13021 caacggccgg atcgagcctg taggcgaaga aaaggtattc ccggctgaaa tggacaatta
    13081 tatccgggaa atttacgcca tcagcggaaa cagagatatg acccgcattc aggagcaggg
    13141 agacgacgac ttctcctttt ccattgtggg gctgtcccgg ttccgcgcaa gtgtgatgaa
    13201 gcagagaggt tctctggcag ccgtcatccg aattgtacgg tttgatctgc caaatccggc
    13261 agacatccac atcccggaga cagtgcttaa cattgcctcc atgaaaaaag gcatggttct
    13321 ggtaacagga gcggcgggaa gcggaaaatc cacaactctg gcctgcgtca tcgaccggat
    13381 caaccagacc aggaacgccc atgtcatcac gctggaagat cccatcgaat atctgcacca
    13441 ccaccagaaa tccgtcgtca cccagcgtga gatcggccac gatacggcct cctatgtgga
    13501 cggcctgcgg gcctccctcc gccaggctcc cgatgtgatc cttctggggg agatgagaga
    13561 ttacgagacc atccagacgg ccatgacggc cgcagagacc ggccatctcc taatctccac
    13621 cctgcacacc accggagcgg ccaacaccat cgaccgaatt atcgacgtgt tccctgcaga
    13681 cggccagcag caggtccgcg ttcagctggc tatggttctg aaggcagtgg tatctcagca
    13741 gcttgtgccg gctgtggatg gttccctgat tccggccttt gagattatgt tcgtcaacga
    13801 ggccatccgg agcatgatcc gggaatctaa aatccatcag attcagaacg tcatctccac
    13861 cagcatggcg gagggcatgg tgagtcttga caacagcctg ttaaaatatc ttcagctggg
    13921 actcattacc cgggaaacct gcgtcagcta cagcccgaac ccagagcaga tgaaaatgcg
    13981 tctgggtgta tagcatgaaa agagggtacc gcggcgtcat cgaattcact ttcaattcag
    14041 gtgacagagc ggtaccctct tctattttgc ttttctttct atttcacttt ccatttcatc
    14101 acaacaaaaa acaccgaccc caacgctctc agtcgccaaa atcagtgctt ttcagtgcgc
    14161 cttcgggggc tcgaaccccg gacaaataga ttaagagtct actgctctac caactgagct
    14221 aaaggcgcat atatgaaatt ttaactttga gaacccttct accggcttct cagtgcgcct
    14281 tcgggggctc gaaccccgga caaatagatt aagagtctac tgctctacca actgagctaa
    14341 aggcgcatat tctgttgctc tcacaggttt ttaaatcctg ttccgtaaca cgcaaattag
    14401 tataactcca gataacaaaa aagtcaatac ctttttttcg cttcttttac agaatttttt
    14461 acaatttttt taatcctatt ttttttccag ccttcccaga gctttctccg cttcctccag
    14521 gcgctttttc cacaaaagca ccgtcctgtt cagctggacc ttgtcgcagg tggctctaga
    14581 aagagcgcgc agcagccgtt ttttcatccc gttttctcct gtgcgtctct ttccttattc
    14641 tatgcccctc tttcctattt gtttcctccg ctctgctcct ctccggctgc tctcacggct
    14701 gtcagcttgc agatcgcctg tcccctggaa gaaaatttct cttcatactc cgtcatcaca
    14761 tttccctccg ccataggact gtggtgcagg tcaaaggtat gctctttcac cttccatccg
    14821 gcctcaggaa tcgattccag ggaatagtcg aacagccccc tgttgtccgt cttaaactcc
    14881 acgtctccgt cctcagccag cacctgatca tagacagcca taaactgggg ggaggtcagc
    14941 ctgcgctttg cgtggcggtc cttgggccac ggatccgaga agttcagata gatcttttcc
    15001 acctctccct tctcgaaaat ttctcccagc tccttagcgt caatgcacat gaaacagata
    15061 ttggaaaccg gaagctgctc ccgtttctga agcgccttta acaaaacggt agaataccgc
    15121 tcaatgccaa tataattaat ctggggattt ctctgagcca gctccataat gaaacgtccc
    15181 tttcccattc ccacctcaat gtgaatcgga ttcctgtttt caaatacgct gtcccacttt
    15241 cccttcattt ccttcggttc ctgaatcaca taggggctct gctcaatagc ctcctccgcc
    15301 cctggtatgt ggcgtaatct catatatttt cctcctggtc tgttcttcca tattccccta
    15361 tcttaccatt tcccacttcc cgttgcaaga catagctgca ggaacggcaa gcttttacac
    15421 tttatgacaa taaacgaaca atttccttac aaatttaatt tttttgaaaa taatggtgca
    15481 gaaaatgtcg agttatatta taatgacagt ataaaaattc agcggcaaag gagatgtctt
    15541 atgagcacag acaatataaa taccagcagc tgggagcgca tacagaaagg ctttcaggaa
    15601 accgaacggc tgctgggaca gaaacggtat aatgaatgta tgatcagagc gagacagact
    15661 ctggaattta tggtgaaatg cctctgcgag cgtttcgata ttatggaagc cagcctggta
    15721 gacatgattg acgctctcta cgagcacgaa attattaaca aaacaacctg cgagcactat
    15781 cacaagatcc gcatgatcgg aaataaggcg gttcacgagg aggataatct ggcatataac
    15841 gcgggacagg cctatcacct gctctcccag gaaatctata cctttgccaa cgatttcaca
    15901 ggcaaaaaga aacgccccgt tccccgctcc caggagagag agcggacaga gacctcctct
    15961 gaaagccatc ctcattcctc cagatcagga gcttcccacg ctccgtccag aggcagctcc
    16021 cggacaggcg gccccgcaag gcgcagacgt ccccgttcct caggcccgtc catcgatcct
    16081 ggcagcctgc ttaaaatttt aattcccgta gcggtcatta tcatcctgat ttttattatc
    16141 cgcatggttc atccagggga agaaaacggc gtggagacga cggctaccat cgaggtagag
    16201 accatcgctc ctaccctgga ggagaccagc acagaggagg agacagaatc tgccgctcct
    16261 gcgaagcggt ataaaacagg cgatacgctg aacgtccgct ctgagccgtc caccagcgct
    16321 tccaagctag gacagctggc gcctggcgct gaggtcaact atatcgaaga ttacgacgac
    16381 acctgggcca agatttcctt cgaaggccag gaaggctacg tatccaaaga atatctggag
    16441 ctgattgcag attagaggat aatatagaaa aagtgaagca ttttcctgtt cccatggaag
    16501 ccaccgaaaa tgtttcactt ttttcttttt cttctgcaat atgtgaaaat ggccgccgga
    16561 aatccggcgg ccattttcgt gaaagagtga attttactat atgtataatc tccgcgccgc
    16621 agaccaatct gcgccgcaaa tattaaacat gcaattttat aagatcagtg acaattaagc
    16681 ctctgtctcc tcctcaactg cctctgttgt ctcctcttca gctgcctctg tctcttcctc
    16741 ggctgcctct gttgtctctt cctcagctac tgttgtctct tcctcagctg cctctgttgt
    16801 ctcctcctca gctgctgctg ttgtctcctc ctcagctgct gctgttgtct caacggctgc
    16861 tgctgttgtc tctgttgctg tctccttgct tccgcaagct gttaatgcaa atgctgttaa
    16921 tgctgctgct gcaaataaaa ctgttttctt cataatattt tttcctcctc tttttacaac
    16981 taaagttata aaattataaa tcctcctgcc gatcggacga aagaaacgaa ccgcttccct
    17041 cctgcatggc ataaccatag tatagtgtct ttttctcaaa aatcaagagt ctgaagaaat
    17101 ttttattaat ttttaataat ttattcgcct tttcgtcata tttctcgtct gctttttcca
    17161 aagactttcg ccttcattta agcttccggt tccatcaggc tgcgaaccag ggcaggaatc
    17221 tcccgtaaat ccccaagctc cctgtccgcc aggcttctgt caaagccgaa gcggtcgtca
    17281 atcagcgccg ccgccttcat tcccgcggcc tttcccgccg tgatgcctac tgtagaatcc
    17341 tcgatggcca ggcactgaga gggatccact ctcagctgcg ccgccgtgtg cagataaatt
    17401 tccggatccg gcttgctccg cttaaacatc tctccgctga ccgcagtttc cagccgctcc
    17461 catacgtggt tcatggtgag aatccgcttc acctgctcca gtcctgtgga ggaagccacc
    17521 gccagcctga ttcccatcgc cttcagctcg tccatcacct ccagaacctc cgggcggaaa
    17581 atggcctgat agtccacctc ctcaaacgcc cgtttccaga ttcctctctc atggtattcc
    17641 cggcgcagct cctcccagct ctgcccgttt gcaacggcct tctccacaat ctcccagcag
    17701 tcccttttcg tggctccgac tgttccgtac agctcctcga tctgaatgtc ccgccttttc
    17761 tccctggcaa attcataaat atactccaga tactttcctt cgctgtcaat gatgactccg
    17821 tccatatcaa aaattaccgc ttttatcacc ctgtcttttc ctccctttga caaatattga
    17881 cagaatttat gccctgattc agccttcatt cgctcattac aggcagtata cacgaacctg
    17941 ccgccctttt caaccgtcgg atttttacgg ttttataaaa tttctttcct ctgcttgcgt
    18001 caggcgtcat taatggtata cttatgtatg acgcaagact ttataataga agtctcgaac
    18061 agttacgccg ccttttagcg aacctgttaa aaggcagaat ggagatttta tgaagcagaa
    18121 aaaccttctg gcctgggcgg ccggaatcct gtgtaccttc tgtctgatga ttatttttct
    18181 catcacatca gcagaatctg tcgtatactg gacgcccggc tattttgaac aggaatatac
    18241 gatgtacaat gtgcctgaaa cggtatccat ggaaatgaac gatttgctct atgtcacaga
    18301 cgagatgatg atgtatctga ggggcgaagg gcaggacgac ctgaacattt ccgttcctgt
    18361 agacggacat acgcgcccct tcttcaatga gcgggaaatg gcccatatgg aggacgtgag
    18421 aaatctgttt atcggcgcgc tgcatctgag aaccgcctgc atcgccgcgg cgtttctttg
    18481 cctggcgctt atgtttctcg taaaagctga cgtaaaacgg attcttccca gagccatctg
    18541 caccggaaca ggcattttta tggttttaac cgccgggctg gctctcctga tatccacaga
    18601 ctttacgaaa tattttatta ttttccacaa aatctttttc gacaatgacc tgtggattct
    18661 ggatcctgcc acggatcttc tgattaatat tgtgccggaa ccattttttg cagatacggc
    18721 ggcgcggatt gcctttacct tcagcttttt agtgctggcg ctgtttttta tctgtctggc
    18781 ctgtatcagg cgctctggaa aacgaaacag aaaggccggg aaggctgcct taagtctcgc
    18841 tctccttctg gctctcgcgg ttccctccca gacagcccat gcgtcagaag agtggcctga
    18901 ggacgtctcc atcgaggcag acgccggcat tgtgattgac gccgcgtccg gcacggttct
    18961 ctacggaaaa aacatccacg agacttacgc ccccgccagc atcaccaagg ttctgacctc
    19021 catcattgtg ctggaacagt gcgatctgga cgaggtagtg acgttctcca aaaatgccgt
    19081 ttacaacgta gaggcggaca gctcttcagc cggctacgac acgggagaca ccgccacggt
    19141 gaaagactgc ctctacgcgc ttctgttaaa gtctgcaaac gagtctgcaa acgctctggc
    19201 agaacacacg gcaggctcca cagaggcctt tgccgagctg atgaacgaaa aggcaaagga
    19261 gctgggctgc gtggactccc actttgccaa tcccagcggt ctgaatgatg aaaaccacta
    19321 tgtcagcgcc tacgacatgg ctctcatcac cagatacgcc ttccagaacg agacgttccg
    19381 cgaaatcgcc tccacgacct actacgagct tccgcccaat gccaggaatc cggaaggcct
    19441 gggcgtttcg ccgggcaata aaatggtcaa aaagaatttc ccggagtacc gccccgacgt
    19501 cattggcggc aaaaccggct atacctccat tgcgctgaat actcttgtaa tcggcgccag
    19561 acaggacgat acagagctga ttaccgtggt gctccacagc aacggaacta cctactcgga
    19621 caccagccgc ctgttagact ttggattcca aaatttccgc tccgtgcctc tggccggaaa
    19681 cgatacctcc tgggagcagt taagcagttc cctgactatt gcagggcttc ccacttccca
    19741 ggccccggct ctgactgtgg atccggacag ccgcattgta cttccaaacc atgcggaatt
    19801 cgacgagacc acctcccaga tctcctttga tctgccggaa aatgccccgg aaaacgccat
    19861 cgcagccatt cactatttcc tgggcagtca cgaggccgga actgcctggc tgacccttgg
    19921 gacaaatgct tccgacagca cgtcccccat tccggcaaag cttttagaga tcgcgccgga
    19981 tacgatcgcc caggtagatt ttaaggatga ggaagaaaaa caggaaggga acgaagccag
    20041 cgcttcccag gaagcagcgg cgtctcagga tggcgaaagc cagaaggaag acggtatgga
    20101 gccgggaaca aaccgttcca aagctcctgc acaggctgat gcttctaaag cagacaaagc
    20161 ttcaaacgaa acgctcaaac agatgcttcc cgttctcatt ctggttctcc tggttctcgc
    20221 agctgcagca ggcctgggag ccgccctctt ccatctcagg aagaaacggc agaaggagga
    20281 aaacgaccgt caggaacgcc gcaggaaacg gctggagcgc ttaaaagaat ccggcgtgtc
    20341 ggaggacgaa ttcaatgaga tgatgaaaaa ccgccgtctg tccatccctc ttgagccaga
    20401 ccggcgttcc tccagacgcc ctaaatcctc ccgcagccat tccggttccc tcctgtccgg
    20461 cgcaggagag gccaggcgtt cttcccgagg ccgggataag ggattctccc tgaaacggcg
    20521 ccgctggtgg aaacgataga gaataaaaaa agagagagaa cggaatcttt atcctcttct
    20581 ctctcttttt ttcatctctt ttttcgcttt cgccctctct gcgcgtttct tcttcgcttc
    20641 ctcacagcgg tgaaccagaa gctccactcc cgcctcatct gtcggcttta ccgtctgtac
    20701 ggcaaacacg ctcccgtcct cagacctttt aattctcagc tttcccttta catatccatg
    20761 ctccgggcag actgccaggc agaaatactg cttctgattg acagaaaacc agcgtatttt
    20821 ctttttcaaa agccggcggc atttgcagca catcacgtct gtcacctgct tttccctcaa
    20881 aagctcctcc ttggtatccc aggttctgga aacaaacttt gcgtatgtgg gaaacttcag
    20941 tctcagctcc tcctcctcta tctccggagt ctgatagtaa tctacagaaa aatattccat
    21001 catactgtag aaatccattt ttcccatcac aagccctgta taccaggcgt cgtctaacgc
    21061 cctgtgaaac gggcgtccct gctcaatccc cagctcttcc actgccgtgt cgagagactc
    21121 ccttctgcca tctccccgga ttaaaccgta aattttctgg agatcatagt aaaacagagg
    21181 tttcccaaag gggagttcca ttccatgata taccacgttt ctctgaagct ccgtcagatc
    21241 catagagccc caggtgcaga gcctgaaatc cgttccgcac caggacaaga aatcctccat
    21301 ggccttctca aaccgctctc cctgctgttc cagcttttcc tgggaaagat gcgtaacctc
    21361 tgatatttta taatgaagcg ttttatacac ctgagggcgc actaaacggc tgaattccga
    21421 tataattctg agattttcgt ccagcttcac tgccccaatc tcaataattt caaaagggag
    21481 ccgatccata gacgtctctc tgcctccgga gctttgattc cactccaggt caagcacaat
    21541 aaaatgtccc atagctctca ttcctattct ttctcactcc gcatccttca ggaaccatac
    21601 cgtttccctc tttctgccgg acaacgtatt aactttacca cattccgccc aataagtcga
    21661 tgatatttta cagaagagcc tctttagggc aaacagatgt cacccgcagg ctctgagtct
    21721 ctcccggaag cgctcatttt ccatcctctg tctgtccgtc tgacacagac atacgttttc
    21781 ctcccgcttt tttcctgcac gtcctatttt cagaccgctc gcctgcccat aatctatccg
    21841 ctttccaatg actaaatata cattttatat gcaccgaata tgtatcaatt tttcttcttg
    21901 tatctgatgc atatttattc atcccttctt ttcttcttgt attcatttgc atgaaaatat
    21961 attcaccgct aatccccagt ctttgttttt ctttctcagt ctcaaaagct ttttcatctg
    22021 ccgtattttc ccattgatgc ttcctgtaaa gcgccggaaa tcggaggact gccgttctgc
    22081 tattctattt tgctctgctg ttctgtcatt ctgtttttcc ttgccttcct ttcagcagtc
    22141 cattataata ggattggctg tttatattcc gccgcttcac cccgcatggc tgacctgatt
    22201 tttagtcaga taagaaatgg cttactatct tgttataact aaaagttatt atacgccttg
    22261 cgagccctat ttatacactt tttaagggag tatgcaaaca tatgaacaca ctaaaacgat
    22321 tcatccatta ttacaagcct tatcaggctc tgttttacct ggatctcatc tgcgcggctg
    22381 tcatcagcat gatcgatctg ctctatccgc agattctgcg cagtctcacc aacactctgt
    22441 ttgccggaga tcctcatctg cttttaaaag ctcttgtccc cattggcatc ggcctcttca
    22501 ttatgtatat cattcaaagc ctatgcaaat tttatgtctg ctatcaggga catatgatgg
    22561 gcgctaacat ggaacgagat atgcggcagc agctctttga tcactatgaa aaactgtcct
    22621 tctcctacta tgacagaaat aattctgggc agatgatgag caaattagta tcagatctct
    22681 ttgatattgc ggaatttgcc catcacggac cggaaaatct gtttatttct ctgattaaaa
    22741 tcgtgggatc ctttatcttt ttattcctga tcagctggca gctggctctc cctctggcct
    22801 ttttagttgt ctgcatgctt gtattctcgt tagctcagaa cggccggatg cagacaactt
    22861 ttatggataa caggaaacga atcggcgacg tcaatgccag tctgcaggac actctggccg
    22921 gaatccgggt tgttcagtcc tttgccaacg aaaaagtgga gcaggaaaaa ttcagaaaca
    22981 gcaatcaccg ttttctgatg tccaaggacg ccaactacca ctgcatggcc agttttatga
    23041 gtttcaacct gtttttccag ggaatgatgt acctggtaac tctggtatgg ggcggatacc
    23101 taatcgccaa aggcgtgctt caggtaactg atttagccat gtacgcgctt tatatcggca
    23161 ttttcatcag ccctatccag attttagtcg agctgactga gatgatgcag aaaggttttt
    23221 ccggcttccg ccgcttcctg gatgtaattg acacagagcc agaaatcaaa aactcacccg
    23281 gcgcagttcc tcttacccag gtcagtggag atgtgcgcta tgacgatgtc agcttttcct
    23341 accaggagga tgagcctgta ttgtctcatg tctccttcca tattccggca ggaaaatccg
    23401 tggccctggt cggaccatct ggaggcggca aaaccacgat ctgttccctt cttcctcgtt
    23461 tttacgatgt gacagaggga agcattttca tcgatggaac agatattaaa acccttactc
    23521 tggaaagcct gagaagtcaa attggaattg tccagcagga cgtctacctg ttctgcggtt
    23581 ctgtaaagga aaatatcgct tacggaaagc ccggcgcttc tatggaagag attatcgacg
    23641 cggcaaaaaa agcaaatatc cacgacttca tccagtctct tccagacggc tacgatacct
    23701 ttgtgggaga acgcggtaca cggctgtctg gcggtcaaaa acagcggatt tctatcgctc
    23761 gggtattcct taagaatcct cctattttaa tcttggacga ggccaccagc gccctggaca
    23821 acgagagcga acgccatatc caaaaaagcc tggaagagct ggctaaaaac agaactacga
    23881 ttaccatcgc ccaccgtctt tctaccattc agaacgcaga cgagattatc gtaatcaact
    23941 gcagcggaat ctccgaaaga ggcacgcatc agcagctgtt ggaaaaaaat ggtttgtacg
    24001 cccactacta tcaaatgcag tttgagggat tgttagaaat agaaaattag attcattata
    24061 gcaggaaaga ttccggccat ccatatgttt cacgtgaaac atacggatgg ccgcttcatt
    24121 tttccgacta atttttttct attattttat cttttcttat tcctccacct gactctcttc
    24181 tccgattcat ccctctttcc cgcctatccc ccttttcctt ttttcttctt ttccctgctt
    24241 ctccttattc gattctctct gttccccctt cttcgcttct ctttattttt ccgtccatac
    24301 actttccttt tcaggtttta aatccgtgtt ttattatatg tttcacgtga aacattacag
    24361 aagcacatgt cagccgattc ctttttcaaa cctttccttt aaacaatcaa tccaggtctg
    24421 aacatgagcg caggtaggtt ctctcaaagc cgccgcatag atctcaaaca cttccggctc
    24481 atgttcctct aaatagcgca gtgatttttt cgggccaaag taatatttca tttctatatc
    24541 aaaaaaagat ttccaggctg tctttcaaca gccagtacat tctgtaaagt ccctctgcat
    24601 cctttctctc cgttctgttt aacattttct ggcaccaggc aagattgtgc tcgttttcag
    24661 ccctcgtctt tgcaggaaag gttttaatat agtcattcac cctttgtttt aggtttttaa
    24721 tcacatcctc ttgatcaaag agaatccggc tatcccagat ctggacaaaa tcctcaacag
    24781 gatactcctg ctgaaacaat gacttaggat aaataaatac atccagttct atgccgcaga
    24841 tcaaggaatg gtcgtggctt atctccccct cctctctcac aagaagggcg tcaaaatcgc
    24901 tgttcaaatg attggtccca ttggcaaaag agccatatac agccatgcca atcggatgat
    24961 aggctgactt taaatattcc attatctttt ccatttttat ttctccgatt caggttttat
    25021 aacagtatca gccatacatt tccttcccaa accttttcgt ggctgatact gttacgattc
    25081 tcacaaaaat cgctcacaaa aattgcaact taagtcttga cttactttag tcagatcagt
    25141 tataataaat aagttagatg gtatattgtt gataaaattt atgtttctgt agctcagcag
    25201 gatagagcgt ccgcctccta agcggaaggc cagcggttcg aatccgctca ggaacactga
    25261 atacaatgcc gaaaaccttg a
//
LOCUS       DBMDUW010000035        24703 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1362_length_24703_cov_5.232989, whole genome shotgun sequence.
ACCESSION   DBMDUW010000035 DBMDUW010000000
VERSION     DBMDUW010000035.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 24703)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 24703)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24703
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1362_length_24703_cov_5.232989"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            340..1152
                     /gene="srtB"
                     /locus_tag="ACZPCR_07815"
     CDS             340..1152
                     /gene="srtB"
                     /locus_tag="ACZPCR_07815"
                     /EC_number="3.4.22.71"
                     /inference="COORDINATES: protein motif:HMM:TIGR03064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004197 - cysteine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0016485 - protein processing [Evidence
                     IEA];
                     GO_process: GO:0045184 - establishment of protein
                     localization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HIR1230816.1"
                     /translation="MKERITKAVFILALIVFLGALGYLGFIWFSYHSAEKGHEQLSEQ
                     VIQREEASPSGDGEEAGNEEAAWAPLTVDFSALKAVSEDAVLWIDIPGTGVSYPVAQA
                     EDNDYYLRRKLNGDNSFAGTVFMDYRNDPAVADDNTILYGHNMRNGSMFGLLKKYGKE
                     EFFLAHPEIDLYLPDRILRCTVISSHQEEAQEENFPMNFESGEEKLAYIDRMKSKAWY
                     DTGISAGEEDRLITLVTCTGNGYSHRFVVQAVVTEEIETASDGVSEALEEKP"
     gene            1182..2120
                     /locus_tag="ACZPCR_07820"
     CDS             1182..2120
                     /locus_tag="ACZPCR_07820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HIR1230817.1"
                     /translation="MESFAVAVNAVMPFLIYISFGYGVRMSGLVDEDFMNKLNKLIFR
                     AFFPILMFNNLYKMEPGSTLDGKLAAVGIASILLLEVLLVLIVPKLVKGNPQRGVVIQ
                     GIYRSNFVLFAIPLTTSLFGEEGAALASMMVAIVIPVYNVTAVIILEMFHGGSSDIKK
                     LVKNVVTNPLIMGAVTGLVFFLLGIHMPSCVNETVSQFAGLTTPLALFVLGGTLHFSA
                     VKGNLKYLVPSLTVKMIVLPAIITVAATAMGFGSLERFVLFTMYATPVATASYSMAQN
                     MGGDGELAGQFVVVSTAASIATIFLWVLLFKSMGMI"
     gene            complement(2248..2418)
                     /locus_tag="ACZPCR_07825"
     CDS             complement(2248..2418)
                     /locus_tag="ACZPCR_07825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015527524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HIR1230818.1"
                     /translation="MAYVITDTCVSCGACAGGCPVGAISEGDGKYEIDAAACIDCGAC
                     AGTCPTGAIEEA"
     gene            2714..2914
                     /locus_tag="ACZPCR_07830"
     CDS             2714..2914
                     /locus_tag="ACZPCR_07830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:2810..2812,aa:Sec)
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HIR1230819.1"
                     /translation="MQINKDMLIGDLVRLDDGIAPILMGSGMHCLGUPASQMESLEEA
                     SMVHGIPVDTLVNAINEYLAQK"
     gene            complement(2997..3770)
                     /locus_tag="ACZPCR_07835"
     CDS             complement(2997..3770)
                     /locus_tag="ACZPCR_07835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HIR1230820.1"
                     /translation="MKIERINENQIRCTLTSFDLSMRNLNLGELAYGSEKARSLFREM
                     IKKAEAEVGFEAEDIPLMVEAIPLSAESIMLVITKIEDPEELDTRFSRFSPVSEEGAP
                     ESALPNELLDGAEQILNLLSPGGGNQETGKPPVSGKAVSSTDSSGTVPEGAGRTYADS
                     LAQRIFCFDSLKTAAQACRIGGQAFEGESLLYKNRRSGKYYLFLRELTPGSEDFIRFC
                     NLLVEYGTSVRAEYASRAYFDEHYERIIREDAVAVLNRL"
     gene            4010..5503
                     /locus_tag="ACZPCR_07840"
     CDS             4010..5503
                     /locus_tag="ACZPCR_07840"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: protein motif:HMM:NF012298.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HIR1230821.1"
                     /translation="MRETEDTVLFGKYQIAGMLGSGRNGSVLLAVHLGLHEYRAIKRV
                     PKEEGSRLREAEILKTLRHPGIPVIYDLYESQEYYYIVQEYLEGRSLSALVQERGSLT
                     RAEILWYGSELCRILVYLHSLKPNPILHLDLQPKNLLICGGTLKLIDFGQSVFASAQT
                     GTEPRFATPGFAAPELYRNEIPDERADIYAIGALLFFMGTGRSPENAVCGDTAQFGGR
                     LKAVIERCLDPRREKRFQTAEELSEALCTVKTGTSGGEGRPLLTIAVAGSRPGSGATH
                     AALALSAFLTVYAGPCLYEEKNASGAAASLGRCIGAAPDRSGIFTAGILSVKPRLGEQ
                     VRPEENSFSIRVLDLGTIREGSEEAYSEISEAAFFLLVCGGREWEFYDCRRALRRLLK
                     MTEPKQIPVRLLINRQDGKERVILPEEASGCMAARLPWIENPFLPLKPEAEQAFFRLF
                     SGTEGEAWLPGGAGGGFRTARRLFSLLRLAKDWRNRRRRGRRRRGGT"
     gene            5593..6159
                     /locus_tag="ACZPCR_07845"
     CDS             5593..6159
                     /locus_tag="ACZPCR_07845"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230822.1"
                     /translation="MIGVAGSSPGVGVTHFSIMIASYLSGVLGKRTALLEENKSGDFA
                     RIFEILSERSVLKQEKGSCSVLEISFMKEAGPETFSDLANSEFDTVVIDFGHDFEAVR
                     TKFQLCQRKFLVGSLAEWKIHSFLKLAEEKKRSDGKWEYFISSGSSEFMKELSRYPGI
                     EARWIPSTEDAFTVSGEVIAFFGGFLEY"
     gene            6257..6508
                     /locus_tag="ACZPCR_07850"
     CDS             6257..6508
                     /locus_tag="ACZPCR_07850"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230823.1"
                     /translation="MKKYEKAEEKRKREAEEKRRYLEGIKRFQKVGVTVLVDGKEPGP
                     QDLEKIVEIREDGAFYMGDYIADESGKLVEIRFDKVYHR"
     gene            6891..8573
                     /locus_tag="ACZPCR_07855"
     CDS             6891..8573
                     /locus_tag="ACZPCR_07855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002601964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 18 protein"
                     /protein_id="HIR1230824.1"
                     /translation="MKNRKNSILKAFCAVFFLAVITGGVFLYWKFGPSRERADLTSVY
                     KADENETVLYLNYEKQEAVGIYENGQTYLPMDWVSENVNSRFYWDEGEEMLVYALPEE
                     ILYADGSSVGSGGQPLILAKEDGVYVSMGLVLNYTKVRIQAFDRTDAKRVFIEDTFEN
                     VPMADVRGTVQVRTKKDVKSPILTECRRGDSVTVLETDEKWVKVATPDGHVGYVKNRK
                     LKNLRSETMESDFKEPVYQNISLDEKILLAFHQVTIPEANGKLEELLEPSEGVNVIVP
                     TWFTLSSNDGDYESLASRGYVDKAHEKGLQVWAMLDNFSKECSKNVQSEILLSKTATR
                     QKLIADMMEEAENYGFDGFNLDFESLKPEAMPHYVQFIREMSIACRERGLVLSVDNYV
                     PSEYTADYNRKEQGIVADYVIIMGYDEHYAGGEKGSTASIEFVEKGITDTLLEVPKEK
                     IINAVPFYTRLWTEEDGKTTSSALGIYKAKEWIDENDVELSWQEDLGQYYGEHKESET
                     ATEYLWMEEEKSLGLKMDLIRKYDLAGTAGWKLGLESPEIWDVIQWDGKEEK"
     gene            8745..9458
                     /locus_tag="ACZPCR_07860"
     CDS             8745..9458
                     /locus_tag="ACZPCR_07860"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HIR1230825.1"
                     /translation="MRAAHFIKRHMTGALCAALLTVFLFSVFRYTGLSAAGRSVHMGT
                     KQPVVVIDAGHGGNDPGKVGIDQSLEKDINLEIAKKLARYLEQADVRTILTREEDKGL
                     YSETDTRKKSADMKARCSLIDEADPDLVVSIHQNSYHQEPVSGGQVFYYTGSVKGKRL
                     AEAVQRRFDYVLGAQNTRKAKENSSYYLLLHVKCPIVIVECGFLSNWQEAARLNSPEY
                     QDRMAWTIHMGVMEYLNTR"
     gene            9757..10836
                     /locus_tag="ACZPCR_07865"
     CDS             9757..10836
                     /locus_tag="ACZPCR_07865"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006782718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HIR1230826.1"
                     /translation="MREEELSFSLEDRNRPQTLTDEDGKVLEEAAAVIRNGGLAAFPT
                     ETVYGLGANALDEKAAKKIYEAKGRPSDNPLIAHIADLDGLKPLVSEIPEAGRKLAEA
                     FWPGPLTLVFPKSRIVPHGTTGGLETVAVRMPSDPVARELIRLAGVPIAAPSANTSGR
                     PSPTRAEHVFQDMDGKIDLIVDGGPVGIGVESTIVDVTEEIPTLLRPGAITMEMLGSV
                     VGKVDVDPAITGPMRADVKPKAPGMKYRHYAPKALLTLVEGDAEAVTARINHLAAEKL
                     GEGLRVGIICTEETKALYPAGMVKSIGLRADEATVAHNLYAVLREFDDLEADVIFSES
                     FPADELGQAIMNRLNKAAGYQIIQA"
     gene            10907..11473
                     /locus_tag="ACZPCR_07870"
     CDS             10907..11473
                     /locus_tag="ACZPCR_07870"
                     /EC_number="3.5.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003500949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004132 - dCMP deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006220 - pyrimidine nucleotide metabolic
                     process [Evidence IEA];
                     GO_process: GO:0009972 - obsolete cytidine deamination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxycytidylate deaminase"
                     /protein_id="HIR1230827.1"
                     /translation="MNGAEKAEETAKTEETVKIRGRVCKSEKRADYITWDEYFMGVAK
                     LAAMRSKDPSTQVGACIVSSDNKILSMGYNGFPIGCSDDEFPWGKEHETDDPYNAKYL
                     YTTHSELNAILNYRGGSLEGSKLYVTLFPCNECAKAIIQAGIRTLVYDSDKYGNTPSV
                     RASKRMLDAAGVRYYKYNPTGRKIEVSL"
     gene            11474..13429
                     /locus_tag="ACZPCR_07875"
     CDS             11474..13429
                     /locus_tag="ACZPCR_07875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008396408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HIR1230828.1"
                     /translation="MKFLLAAVNAKYIHSNLGVYSLKKYADEKRKQQGTAFSGPDWEI
                     EIGEYTINHQMDYILQGIYEKAPDAVGFSCYIWNILYVQELIRDLKKVLPQTEIWLGG
                     PEVSYRAEEFLRKEPSARGVMAGEGEETFFRLLGAAKRQDAGSSVWRDEALEQIPGLV
                     FRREAGSGSSSGPETGEIVKNPPAPLMDLDDIPFVYSDLRGMENRIIYYESSRGCPFS
                     CSYCLSSIDKMVRFRSLDRVKWELAFFLENRVPQVKFVDRTFNCKKSHSMEIWRFIQE
                     HDNGITNFHFEISADLLSEEELSLLSQMRPGLVQLEIGVQTTNPDTIREIRRRMDLGK
                     LESHVRQINGFGNIHQHLDLIAGLPWEGYESFKRSFNQVYAMEPEQLQLGFLKVLSGS
                     YMEERAQDYGLRFRDTPPYEVLATRWLSYGELIRLKGVEEMVEIYYNSGQFRNTVKEL
                     QKEFLSPFDMYESLREYYREEGLSAVSHSRNARYEILFAFIEKTLGKRPQTGVQTSAQ
                     TEGQTEEQAEDRTEEPADRLELYRDLLTEDLYLRENAKSRPSFARDLSPFKEEIKQFF
                     IREGKEPCRLTGYEGYDSRQMSRMAHMEVMRDGRMLLFDYLCRDALLGNARTIEAGRI
                     RGDNETAEPGERRKQKIIYHFYEKGEQ"
     gene            13426..14088
                     /gene="nth"
                     /locus_tag="ACZPCR_07880"
     CDS             13426..14088
                     /gene="nth"
                     /locus_tag="ACZPCR_07880"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HIR1230829.1"
                     /translation="MAVRRETKAQKAERVKRILELLDQEYGTEYRCYLNHETPWQLLI
                     AVIMSAQCTDARVNIVTETLFKKYDTLEKFAAADQRELEQDIHSIGFYHSKAKNIIAC
                     CQALVERFGGQVPERMEDLLTLAGVGRKTANVIRGNIYNEPSIVVDTHVKRISRKLGL
                     AKEEDPEKIEYELMKVLPKDHWILWNIHIITLGRTICTARNPRCRDCFLREECPGKEA
                     EL"
     gene            14121..14837
                     /locus_tag="ACZPCR_07885"
     CDS             14121..14837
                     /locus_tag="ACZPCR_07885"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006782714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HIR1230830.1"
                     /translation="MGNSYLALDLETTGLDPKRDKIIEIGACRVRDGEIEKELSLLIH
                     PHQPLPERITALTGITDEMLSEAPDMESVIGQVMDFCGDLPILGHHVIFDYSFLKRAA
                     VNAGFPFERTGIDTLGLCRRFMPEEEKKNLSAACAWYQVPEETAHRALSDARMAHFLY
                     QKIRALNISGHEETFLPKPLIYKVKREQPASKKQKEGLRELAKYHRINLSVDIEYLTR
                     SEASRMTDKIIFQYGRMKKR"
     gene            14980..16503
                     /locus_tag="ACZPCR_07890"
     CDS             14980..16503
                     /locus_tag="ACZPCR_07890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003509909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HIR1230831.1"
                     /translation="MKRNLWTAGLTAALSAGILFMQPVIAEAGILPEGFSVAGAGDEA
                     LDFSGQTAEEASGKLEEYVGSMAEEKISISIDGTSFSSTAGDLGLYWENKEELNAAIG
                     EYSGGNLLERFARTKKLEKEPLSLAVKASLDDEKLSAFVNDNCAPYVREARDASISRE
                     NGAFVITDEEIGLGVDFEATREALNTALNQGISDSISVEAVVTEAEPRIHRSDLESIS
                     DVLGTFSTNFNAGDRSRTQNLKTGAGKINGTVLMPGDEFSAYTWLTPFTIENGYAAAG
                     SYENGRTVDSIGGGACQLCTTLYNVVLRAELEVTQRQNHSMTVGYVKPSEDAAIAGTY
                     KDLKFKNNYDTPIYLEGSVAGNTLTFTAYGKDTRPEGRTVEFVSETLGTTDPGAPVEK
                     PDPSLAPGARVKESSGHVGKKSRLWKVVYENGVETGREILHTDTYMASKAVYRVGPAA
                     PSVPAVTEPSTPAETQPQENAPVQEQPSGPAGPASEPVSPAAPAADPASVPAPRAPA"
     gene            16526..17116
                     /locus_tag="ACZPCR_07895"
     CDS             16526..17116
                     /locus_tag="ACZPCR_07895"
                     /inference="COORDINATES: protein motif:HMM:NF014788.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIR synthase-related protein"
                     /protein_id="HIR1230832.1"
                     /translation="MNRHLNQEQEKRPGSLKPGQDLIIAGSIGLTGAALAARAGEKAV
                     RERFSSQYAERIFTLDQGLLSQEEAEEIGRLAGATDMEPVGEGGFMNCLWRLLEAYGL
                     GCIIELRAILLRQETVEACEVFDLNPYRLHSAGCFLMAADSGFEAVREIERRGFEGAV
                     IGAVKPGPARRILNGEIETFLDRPKADELEKLGLLK"
     gene            17229..17711
                     /locus_tag="ACZPCR_07900"
     CDS             17229..17711
                     /locus_tag="ACZPCR_07900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013271088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HIR1230833.1"
                     /translation="MRERILAVIEKNSRISTAELAEILGENEAAVAAEIAEMEEEHII
                     CGYHTLINWDNTEDEKVIALIEVKVTPQRQMGFEKIAERLSLYSEVKAVYLMSGAFDF
                     TVIIEGKSMRGVAQFVSEKLATIDSVISTATHFVLKKYKDHGTVLNDGPQDERMLINP
                     "
     gene            17708..18937
                     /locus_tag="ACZPCR_07905"
     CDS             17708..18937
                     /locus_tag="ACZPCR_07905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006782709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HIR1230834.1"
                     /translation="MRNPLSNTIVTIPPSGIRKFFDIVSEMEGAISLGVGEPDFDTPW
                     HVRDAGIRSLEMGKTFYTSNAGLKELKQEICNYLKRRMQVEYDYNTEVMVTIGGSEAI
                     DVALRAMLDPGDEVLIPQPSYVSYVPCTILAGGVPVVIELEEKDQFRLTREKLLEKIT
                     DKTKVLVLPFPNNPTGAIMEREDLEAVAKVVEEKDLFVISDEIYAELTYKKKHMTIAS
                     LPGMRERTVLINGFSKAYAMTGWRIGYACAPALILKQMLKIHQYAIMCAPTTSQYAAV
                     EAVKNGDADIEEMKRSYDERRRYLLKEFRSLGMDCFEPYGAFYMFPSIKRFHMTSEEF
                     ATRLLREEKIAIVPGTAFGDCGEGYLRVSYAYSLEDLKRAIRRIRRFVNRLDEENGAG
                     EKSGQPDQEEKRAGKQR"
     gene            18957..19448
                     /locus_tag="ACZPCR_07910"
     CDS             18957..19448
                     /locus_tag="ACZPCR_07910"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003500933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0141098 - tRNA
                     (cytidine(34)-2'-O)-methyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HIR1230835.1"
                     /translation="MNIVLYEPEMPANTGNIGRTCVATGTRLHLIEPLGFKLNEKALK
                     RAGLDYWDKLDVTVYSDFQDFLDRNPGAKIYMATTKAPNVYTEASYEPDCYIMFGPES
                     RGIPEDILVNHQETCVRIPMWGDIRSLNLSNSVSIILYEALRQNGFEKMTMQGHLRNY
                     DWQ"
     gene            19473..20612
                     /gene="nagA"
                     /locus_tag="ACZPCR_07915"
     CDS             19473..20612
                     /gene="nagA"
                     /locus_tag="ACZPCR_07915"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HIR1230836.1"
                     /translation="MILQSTRVWAAGQFLPLQLQIEGDKIVQVLEYKSQEADEDWGDK
                     RIVPGFIDVHTHGAYGFDTNDAEPEGLKDWMRRIPEEGVTSILPTTVTQMPEVLSAAV
                     KNVADVAEGEYEGAEILGIHFEGPFLDMEYKGAQPPEAIAVPSVEQFKKYQEAARGHI
                     RYITLAPEHDPGLALTRYLKQTGVVVSMGHSCATYEQAMLAIANGASSMTHVYNGMTA
                     FTHRKPGLVGAAFRVRDIYGEVIADGHHSHVSALNNFYQLKGRDFAMMVTDSLRAKHC
                     PPGGKYQLGGHDIEITAEGLAYLKGTNTIAGSTLHMNRGLQILVEKAMIPFDSALNSC
                     TINPARCLGVDDRKGKICAGYDADLVVLEDNYDVAQTYCRGRKML"
     gene            complement(20772..21515)
                     /gene="nagB"
                     /locus_tag="ACZPCR_07920"
     CDS             complement(20772..21515)
                     /gene="nagB"
                     /locus_tag="ACZPCR_07920"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019160449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HIR1230837.1"
                     /translation="MRIIEAANYEDLSRKAADLIAAQVILKPDCVLGLATGSTPEGTY
                     KELVTRFEQGVLDFSQVSSVNLDEYRGLSEDNDQSYRYFMNHHLFDHVNIDKARTHVP
                     NGKEPDSDKACADYDAQILSMGGVDLQLLGIGGNGHIGFNEPCGEFVVGTHCVDLTQS
                     TIEANARFFSSIDEVPKQAYTMGIGNIMAAKKILLLASGTGKAQAIFDTCFGPVTPHV
                     PASVLQLHPDAVIIADTEALSLAKEKGVF"
     gene            21803..23326
                     /locus_tag="ACZPCR_07925"
     CDS             21803..23326
                     /locus_tag="ACZPCR_07925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007490213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HIR1230838.1"
                     /translation="MRGVETRIQEIRHRIFREVARMAYHTEWPVDKRIEELPYKIIPG
                     EVGNFRNDVFLERAIVGERLRLAMGLPCRGAAEHAPLSDNIEAADKAETYYTPPLINV
                     IKFACNACHEKRVYVTDGCQGCLAHPCVEVCPKGAVTLDRTNGRSYIDQDKCIKCGKC
                     KDVCGYNAIIVQERPCAAACGMDAIHSDANGKAEIDYEKCVSCGQCLVNCPFGAIADK
                     SQIFQVIRAIQSGERVYAAVAPAFVGQFGPKVTPGKMRAAMKQLGFADVFEVAIGADL
                     CATQEAIDFMKEVPNEIPFMATSCCPAWSMMAKKLFPEQANCISMALTPMTLTARLIK
                     SKHENAKIVFIGPCAAKKLEAMRRSVRSEVDFVLTFEEMAGIFDAKHVDIENMEEDPD
                     GVNDASTDGRNFAVAGGVAQSVVNVIKKRFPEREIKIANAEGLKDCRKLLTLAKAGKY
                     NGYLLEGMACPGGCVAGAGTMQPIKKSQAAVKQYASKAQHATSSETEYVKELDKLVD"
     gene            23569..23955
                     /locus_tag="ACZPCR_07930"
     CDS             23569..23955
                     /locus_tag="ACZPCR_07930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008396388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HIR1230839.1"
                     /translation="MKIAIPYAEEQVFQHFNEASQFKIYTVDEFDILEEELVSISQDT
                     PAQTAAALKAQGVNVVICGNIGVASLLNLQDAKIQVMGGAYGAAREQVEKFLNGQLHF
                     ETKESRSQQQSGESNGNVSACGNQCF"
     gene            complement(24020..24319)
                     /locus_tag="ACZPCR_07935"
     CDS             complement(24020..24319)
                     /locus_tag="ACZPCR_07935"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230840.1"
                     /translation="MIEKLLSIDETAKIFVQVYGLEEDNNEQCITADTLIIFSKLSLY
                     EIKQIFNEPKDIFPSDIREVTDFSQSTFLIDNNGKLIPSVKLFGDDCFVYYCWWD"
     gene            complement(24576..24683)
                     /locus_tag="ACZPCR_07940"
     CDS             complement(24576..24683)
                     /locus_tag="ACZPCR_07940"
                     /inference="COORDINATES: protein motif:HMM:NF026918.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Imm53 family immunity protein"
                     /protein_id="HIR1230841.1"
                     /translation="MSWLHCKVTNKIFSAACSPNNLVTVLEIFKSWIEE"
BASE COUNT         6601 a         5408 c         7156 g         5538 t
ORIGIN      
        1 agcatagatt ttctgatgtt ctgaaagata ggaatcagag aaataggaac ctggaaccag
       61 gttcgaagtg gtgaaatgta tgcttttgtg gttattgtac ctgtcccact aagctcgaaa
      121 agaccttgct aagtggggca ggtatgtatt ctcactagac tcgtgaaaaa cctcgtcaag
      181 tgttcacatt ataccatagg caagaggaaa ctacaacgag gaaactctgg tttttatgtc
      241 atatttttgc tatactgatg aatagaagca gatggaaatc tgctatcaat aaacaggaga
      301 acaggggaat ttgttccctt gccaggaggt ttacataata tgaaggaaag gatcacaaaa
      361 gctgttttta ttctggcgct gatcgtattt ctcggcgcgc tgggatattt gggatttata
      421 tggttttcct accattcggc tgagaagggc catgaacagc tgtctgagca ggtgattcag
      481 cgggaggagg cttcaccgtc tggagacggg gaggaggctg ggaatgagga ggcagcctgg
      541 gcgcctctga cagtagattt cagcgctctg aaagctgtct ctgaggatgc ggtgctttgg
      601 attgacattc caggcacagg cgtcagctat ccggtggcgc aggcagagga caatgactac
      661 tatctgagaa gaaagctgaa cggagacaac agctttgccg gcacagtgtt tatggattac
      721 agaaatgatc cggcagtggc ggatgacaac acgattctct atggccacaa catgaggaac
      781 ggatctatgt tcggactgct gaaaaagtac ggaaaggaag aatttttcct ggctcatccg
      841 gagattgatt tatatcttcc agacagaatc ctgcgctgta ctgtgatttc cagccaccag
      901 gaggaggcgc aggaagagaa tttccctatg aattttgaga gcggggaaga gaagctggct
      961 tatatagaca gaatgaaatc caaggcctgg tatgatacgg gaatttcggc aggagaggag
     1021 gatcggctga ttactcttgt cacctgcacg ggcaatggat acagccaccg atttgtggtg
     1081 caggctgtgg tgactgagga gatagagaca gcttctgacg gcgtttcaga agctttagaa
     1141 gaaaagccgt aaggccggct taggcagagg agacagagat tatggaaagt tttgcagtgg
     1201 cagtcaatgc ggttatgccg tttttgattt atatttcctt cggatacggt gtgcggatga
     1261 gcggactggt ggatgaagat tttatgaata agctgaacaa gctgattttc agggcgtttt
     1321 tcccgatttt gatgtttaac aatctctata agatggagcc gggatcgacg ctggatggaa
     1381 aactggcggc agtgggaatt gccagcattc tgcttctgga ggttctgctg gtgctgattg
     1441 tgccgaagct ggtgaaggga aatccgcaga ggggcgtggt gattcaggga atttacagga
     1501 gcaattttgt cctgtttgcc attccgctga ccaccagcct gttcggcgag gagggagcgg
     1561 cgctggcctc catgatggtg gccattgtca taccagttta caatgtgacg gcagtgatta
     1621 ttctggaaat gtttcacggc ggaagctcag atataaaaaa gctggtgaag aatgtggtta
     1681 cgaatcctct gattatggga gctgtgacgg gacttgtgtt tttcctgctc ggcattcaca
     1741 tgccgtcctg cgtgaacgag actgtgtccc agtttgcagg cctgacaacg ccgctcgccc
     1801 tgtttgtact ggggggaacc ctgcattttt ctgctgtgaa gggaaatctc aaatatctgg
     1861 ttccttctct gacggtaaaa atgatagtcc tgcctgccat catcacggta gctgccacag
     1921 ccatggggtt tggaagcctg gaacgcttcg ttttgtttac catgtacgcc actcctgtgg
     1981 cgacggcgtc ctattccatg gctcagaata tgggaggaga cggcgagctg gccggacaat
     2041 tcgtagtcgt cagcacagcg gcctctatcg ctacgatttt cctgtgggtt ctgctgttta
     2101 agagcatggg aatgatataa acagatgata taaacaaaaa caaaaaagag actgggcaga
     2161 agtgctgaat aatcagacct tctgcagcag tctctttctt ttgcaataca tcgcaatctc
     2221 cgtcataaac ggaacaatca gcttaaatta agcctcctcg attgcacctg ttgggcatgt
     2281 accagcgcaa gctccgcagt cgatgcaagc agcagcgtcg atctcgtact tgccatctcc
     2341 ctcgctgatt gcgcctactg gacatccgcc agcgcaagcg ccacagctaa cgcatgtatc
     2401 tgtaattaca tatgccatga taaattacct cctttaatta tggttgtgcc tacattttat
     2461 actaaactcc gaaaatattc aagatggtac cctaaaaaaa cttgttctaa aataaaagca
     2521 aggaaataaa agggaatatt ttgacggata aaggggaaca atagaacgga atgagagatt
     2581 ttccgatagt attttacaaa tttccatgct tttctgatat cgtggcgctg aatcaggttg
     2641 aaatatgcct tgcaatggga attaaaaagt attatattat tgaatgtaga aaacagcaca
     2701 aggaggtaca aacatgcaga ttaataaaga tatgttaatc ggtgatctgg ttcgtctgga
     2761 cgacgggatt gcacctatcc ttatgggatc aggaatgcat tgcttaggct gaccggcttc
     2821 acagatggag tctctggaag aggccagtat ggttcacgga atcccggttg atacgttagt
     2881 aaacgcgatc aatgaatacc tggctcagaa gtaattctga agcaggatag aataaaaggc
     2941 agatgagagg gagcgttccc tgttcacctg ccttttttat tgccgttgcg gggcttctac
     3001 agcctgttca gcacggccac ggcatcctcg cggatgatgc gctcatagtg ctcgtcaaag
     3061 taagcgcggg acgcatactc ggcccggacg ctggttccgt actccacaag aagattgcag
     3121 aaacggataa aatcctcgga tccgggagtc agctctctga gaaacagata gtatttcccg
     3181 ctgcgtctgt ttttatagag aaggctttcg ccttcaaagg cctgtcctcc gatgcggcat
     3241 gcctgggcag ccgtttttaa gctgtcaaag cagaaaatcc gctgagccag ggaatcggcg
     3301 taggttctgc ctgctccctc tggaacagtt ccagaagagt ctgtggaaga aaccgccttt
     3361 ccagacacag gaggcttgcc tgtttcctga tttcctccgc ccggggagag aagatttaag
     3421 atctgctctg cgccgtccag cagttcgttt ggaagagcgc tttcaggcgc tccttcctcc
     3481 gacacaggag agaaccggga gaaccgggtg tccagctcct ccggatcctc gatttttgta
     3541 attaccagca taatgctttc cgctgacaga ggaatagcct ctaccataag aggaatgtcc
     3601 tcagcctcaa atccgacctc agcctcggcc ttctttatca tttcccggaa caggcttctg
     3661 gctttttcgg agccataggc cagctctccg agattcaggt tcctcatgct taaatcgaag
     3721 ctggtgagag tgcagcggat ctgattttcg ttgatgcgtt ctattttcat gggatcactc
     3781 gcctttcgtt atcgtccgta ctacagggac attacagccg gaattaagat tctatatacc
     3841 caatatacta tataatataa ggaattggca attcatatgt gaaaaattta tagaaaattt
     3901 tatgaaattt tcctaaaagt ggttgtaaat cgtgacccca tgtattagaa tacaggctaa
     3961 gaagtggtat ttcccatgac tgttcagata ccggcggttc cgagaggagg tgcgggagac
     4021 agaagatact gtactgtttg gaaaatacca gatagccggg atgcttggaa gcggaagaaa
     4081 cggttccgtc ctgttagcgg ttcacctggg ccttcatgaa tacagggcca tcaagcgggt
     4141 gccgaaggag gagggaagcc ggcttcgtga agcggagatt ttaaagacgc tgcgtcatcc
     4201 ggggataccg gttatctacg atttatacga gtctcaggaa tattattaca ttgtccagga
     4261 atatcttgaa ggacgttctc tatctgccct ggttcaggaa aggggcagtc ttactcgagc
     4321 agagatcctg tggtacggga gtgaactctg ccgaatcttg gtttatctgc attcgctcaa
     4381 accaaaccct attttacatt tagatcttca gcctaagaac cttttgatct gcggcggcac
     4441 gcttaaatta attgatttcg gccagtctgt ttttgcgtct gcccaaacgg gaacagaacc
     4501 gcgctttgcg actcccggct ttgccgcccc ggaactgtat cgaaatgaaa ttccggatga
     4561 gagagcagac atttatgcca ttggtgccct cctgtttttt atgggaacgg ggagaagccc
     4621 ggagaatgct gtctgcgggg atacagctca gtttggcgga cgcctgaaag cggtcataga
     4681 aaggtgtttg gatccgcggc gggaaaaacg gtttcagacg gcggaggaat tatcagaggc
     4741 gctctgcact gtgaaaacag ggacttccgg tggagagggg agaccacttc ttacgattgc
     4801 tgtggctgga agccgcccgg gatcgggcgc tacccatgca gcgttagctt tgtcggcttt
     4861 tttgacggtt tacgcaggcc cttgtctcta cgaggagaaa aatgcttccg gagcggcggc
     4921 ctctctgggc cggtgcatcg gcgcagcgcc tgacaggagc ggaattttta cagctggaat
     4981 tttgtcagtg aagccgcgcc tgggagaaca ggtccgcccg gaagaaaaca gtttttccat
     5041 ccgggtactg gatctgggaa ccataagaga aggatcggag gaggcgtatt ctgaaatcag
     5101 tgaagcggcc ttttttctgc ttgtctgcgg agggagggag tgggagtttt acgactgccg
     5161 gagggctttg agaagacttc ttaaaatgac ggagccaaaa cagattcccg taagacttct
     5221 gattaatcgg caggacggaa aggaacgggt gattttgccg gaggaagcgt caggctgtat
     5281 ggcggcccgt cttccctgga ttgagaaccc gtttcttccg ctgaagccgg aagcagaaca
     5341 ggcatttttc cgcctgtttt caggaacaga gggagaagca tggctgccag ggggagcagg
     5401 aggcggcttt cgaacggcgc ggcggctttt cagtcttttg aggttggcga aggactggag
     5461 aaacaggcgc agacggggac ggcgccggag aggagggaca tagactgaag agaaaaataa
     5521 aaatacagaa gtagctggag acaaaagaaa agaggggcgt tttggaggaa aggcagtttt
     5581 ccccatcctc tgatgatagg ggtggctgga agcagcccag gcgtgggagt tacgcatttt
     5641 tccatcatga tcgcttccta cctttcaggc gtcctgggaa agcggacggc tctgctggag
     5701 gaaaataaaa gcggagattt tgcgcggatt tttgagattt tatcggagcg gtctgtctta
     5761 aaacaggaaa aaggttcgtg tagtgttttg gagatttctt ttatgaagga agccggtccg
     5821 gagacgttct cagatttggc caattcagaa ttcgatacag tggtaattga ttttggacat
     5881 gattttgagg cggtgagaac aaaatttcag ctttgccaga gaaaatttct ggtaggttcc
     5941 ctggctgagt ggaaaataca ttcgtttttg aagctggcag aagagaaaaa acgctcagac
     6001 ggaaaatggg agtattttat cagctcaggg agcagcgaat ttatgaagga gctttcaaga
     6061 tatccgggca tagaggccag gtggattcca agcacggagg atgcatttac ggtgtcaggg
     6121 gaggttatcg ctttctttgg gggatttctg gaatattaaa gaagggcaga cagaatagac
     6181 ataatatatc acgatattag agttataaaa cctcctggga ggaatttcag gctgcccttc
     6241 agacaggaga agataagtga agaagtacga aaaagcagaa gaaaagagga aacgggaagc
     6301 agaggaaaag cggcgctatc tggagggaat caagcggttt cagaaggtgg gcgtcacagt
     6361 gttggtggac ggaaaagaac cggggccgca ggatcttgag aaaatcgtag agatccggga
     6421 ggacggggct ttttatatgg gagattacat tgcagatgaa tcgggaaagc tggtggaaat
     6481 ccggtttgac aaggtttatc acagatagag aagagaggag atacggtatc gaagagagaa
     6541 agatagagaa acctgggaaa tagaaggaga agaagggaaa atcctggcat aacccagagc
     6601 aggagaacat tcagaggatg ctgttatgcc tgaacacagc gataaaagcc tgcgctcttc
     6661 gttttgtcag gaatttcccg gactctcaaa aaatcaaaca gaaatgtaag aaaaagttca
     6721 aatctattta tccggagtgt ggtataatgt acgcgggcag aaaaacaagc ggcaccgtag
     6781 gtgacatttg tttttcgccg cgataacgag caaaccgtct gcggagcaga cagggagcgc
     6841 agcgcgcgtg tttgcgagta catgtcatca gatttttccg gaggatagat atgaagaaca
     6901 gaaaaaattc tattttaaaa gcattttgcg cagtgttttt tctggctgta attacaggcg
     6961 gcgtttttct ttactggaaa tttggaccat ccagggagcg cgccgattta acaagcgttt
     7021 ataaggcaga cgaaaatgag acagttttat atttgaatta tgaaaaacag gaggctgtgg
     7081 ggatttatga aaacggccag acgtatctgc ccatggactg ggtgagcgag aacgtcaaca
     7141 gccggtttta ctgggatgaa ggggaggaga tgctggttta cgctcttccg gaggagattc
     7201 tctatgctga cggcagttct gtgggaagcg gcggccagcc tctgatttta gcgaaggagg
     7261 acggcgttta tgtgtccatg gggctggtgc taaattacac gaaagtcaga atccaggcct
     7321 tcgaccggac cgatgcgaaa cgagtgttta ttgaggatac ctttgaaaac gtccctatgg
     7381 ccgatgtgcg cggaacggtg caggtcagga cgaaaaagga tgtgaagagc ccgattttga
     7441 cagagtgcag aagaggggac agcgtcacag ttctggaaac agatgagaaa tgggtaaagg
     7501 tggctacgcc ggacggtcat gtaggctatg taaaaaacag aaagctgaaa aatctccgtt
     7561 ctgagacgat ggaaagtgac tttaaagagc cggtgtacca gaatatttcc ctggatgaga
     7621 aaattcttct ggcgtttcat caggtgacga ttccagaggc caatggaaag ctggaggagc
     7681 ttttagagcc gtccgaggga gtcaatgtga ttgtgcccac ctggtttacg ctcagcagca
     7741 atgatgggga ttatgaatcc ctggccagca gaggctatgt agataaggcc catgagaagg
     7801 gacttcaggt ctgggccatg ctggacaatt tcagcaaaga atgcagcaaa aacgtccagt
     7861 ccgagatcct gctgtccaaa accgccacca ggcagaagct gattgcagat atgatggagg
     7921 aggcagaaaa ctacggcttt gacggcttta acctggattt cgagagcctg aagcctgaag
     7981 cgatgccgca ctatgtccag tttatcaggg aaatgtctat tgcctgccgg gaacgggggc
     8041 ttgtcctctc tgtggataat tacgtgcctt ccgagtacac ggctgattat aacaggaaag
     8101 agcagggaat cgtggcggac tatgtgatta tcatgggcta cgacgagcat tacgccggag
     8161 gcgagaaggg ctctaccgct tccatcgaat ttgtggaaaa gggcattaca gatacgcttc
     8221 tagaggttcc gaaggagaaa atcatcaacg ccgttccatt ctacaccaga ctctggacag
     8281 aagaggacgg gaagacgacc tcgtcggctc tcggcattta caaggccaaa gagtggattg
     8341 atgagaatga cgtggagctt tcgtggcagg aggatctggg gcaatattat ggcgaacata
     8401 aggaatccga aacggccaca gagtatctct ggatggaaga ggagaaatcg cttggtctta
     8461 aaatggattt aatcagaaaa tatgatctgg ccggaacagc cggctggaag ctgggcctgg
     8521 aaagtcctga aatctgggat gtgatccagt gggacggcaa agaagaaaaa tagaagaagg
     8581 agagccagga aagctcctgt gcattttgca gagagaaagc gtttctgttc cagcgaagga
     8641 tcagaaccgc tttctctttt ccattttctg tacgcggatg gcatacatgg gacaggatag
     8701 gaacggaata tactgaacgg aacgaagcgc attcaggtgg agagatgaga gcagcccatt
     8761 ttataaagcg gcatatgaca ggggcgcttt gcgcggcgct tctgactgta tttttatttt
     8821 ctgtctttcg gtatacggga ctttccgcgg cgggaagaag cgttcacatg ggtacgaaac
     8881 agccggtggt ggtgattgat gcgggacacg gaggcaatga tccgggaaag gtggggatag
     8941 atcagagcct ggaaaaggat attaacctgg aaattgccaa aaagctggcc cgctatctgg
     9001 aacaggcaga tgtgaggaca attctgacaa gggaggaaga caaaggactt tacagcgaga
     9061 cggataccag aaagaaatca gctgatatga aggccagatg cagcctgatt gacgaggcgg
     9121 atccggatct ggtggtcagt atccaccaga acagctatca ccaggagccg gtatccggcg
     9181 gacaggtctt ttactacact ggatctgtaa aaggaaaacg gctggcagag gcggtacaaa
     9241 ggcggttcga ttatgttctg ggggctcaga ataccagaaa agccaaggaa aacagcagtt
     9301 attatctgct gcttcatgta aaatgtccca ttgtgatcgt ggagtgcgga tttctctcta
     9361 actggcagga ggcggccaga ctgaattctc cggaatatca ggacaggatg gcatggacga
     9421 ttcacatggg agtgatggaa tatttaaata ccagataggc ggttcagatc ttttccggaa
     9481 cagagaaaaa ggatacagac cttttcgcga aaaccttgct gccaccgcgc tgccaccgca
     9541 ttgccaccgc agggcctgca gtcttgcacc tgcctgattc ctgtgctatg atagcgtcag
     9601 tatacaaaag gcaatagaga agcatatgag gaagacagag gaacggcagg cggatcgcct
     9661 aaacaggaaa gggaagctac gctgccagaa agaggttaaa cagtcatgga tcagataaaa
     9721 acgaaggttg taaaaatcaa tgaggcgtac agaaggatgc gggaggagga gctgagcttt
     9781 tctctggaag acagaaacag gccgcagact ctgacggacg aggacggaaa ggttctggag
     9841 gaagcggcag cagtgatcag aaacggcggc cttgcagcat ttcccacgga gactgtgtac
     9901 ggtctgggag cgaacgcgct ggacgagaag gcggctaaga agatttacga ggcgaaggga
     9961 cgcccttccg acaatccgct gattgcccac attgccgatt tagacgggct gaagccgctg
    10021 gtatccgaga taccggaggc gggaagaaag ctggcagagg ccttctggcc agggcccttg
    10081 actttagtat ttcccaagag caggatcgtg ccccacggca ccacaggagg cctggagacg
    10141 gttgcggtgc gtatgcccag cgatccggtg gcaagagaac tgatccggct ggcaggcgtg
    10201 cccatcgccg ctcccagcgc caatacttca ggccgcccca gccctaccag agcggagcat
    10261 gtatttcagg atatggacgg aaaaattgat ctgattgtgg acggcggccc ggtgggaatt
    10321 ggggtggagt ctacgattgt agatgtgacg gaggagattc ccactcttct gcggccggga
    10381 gctattacca tggaaatgct tggcagcgtt gtgggtaagg tggatgtgga tccggcgatc
    10441 acaggcccca tgcgggcaga cgtgaagccc aaggcgccgg gcatgaaata ccgccattat
    10501 gcgcccaagg cgttgcttac tctggtggag ggagacgcag aggcggtgac ggcccgtatc
    10561 aatcatctgg cggctgaaaa gctgggggag gggctcagag taggcattat ctgcacggag
    10621 gagacgaaag cgctctatcc ggccggaatg gtaaaaagca tcggcctgcg ggcagacgag
    10681 gctacggtgg cccacaacct ttacgctgtg ctcagagaat ttgacgatct ggaggcggac
    10741 gtgatctttt ccgagagctt tcctgccgac gagctgggtc aggcgattat gaaccggctg
    10801 aataaggcgg cgggctacca gatcattcag gcataacgcc gggaacaaaa gggcagagtg
    10861 aacgaacgcc ggaattaaaa acggcaaagc aggaggaggc agtaccatga acggggcaga
    10921 aaaagcagag gaaacggcaa agacagaaga gacagtcaaa atcagaggca gagtctgcaa
    10981 atcagaaaag agggcggatt acattacctg ggacgagtat tttatgggag tcgccaagct
    11041 ggcggccatg cgatccaagg atcccagcac ccaggtgggg gcctgtattg tcagcagcga
    11101 caataagatt ctttccatgg gatacaacgg atttcctatc ggctgttcgg acgacgaatt
    11161 tccgtgggga aaggagcatg aaacagacga tccctacaat gccaagtatc tctatacgac
    11221 tcacagcgag ctgaacgcca ttttgaatta caggggaggc agtctggagg gcagcaagct
    11281 ctacgttacc ttatttccct gcaacgagtg cgccaaggcg attatccagg cgggcatccg
    11341 cacactggtc tacgacagcg acaaatatgg aaacacgccg tccgtccggg cctctaagag
    11401 gatgctggac gcggcgggag tgaggtatta caaatacaat ccaacgggaa gaaagataga
    11461 ggtatctctg tagatgaaat ttttgctggc ggcggtaaac gccaagtata ttcactcgaa
    11521 tctgggcgtc tacagcctga aaaagtacgc ggacgagaag agaaaacagc aggggacggc
    11581 tttttctggg ccggactggg agatagagat aggggaatat accattaacc accagatgga
    11641 ttatattctg cagggcattt atgagaaggc tcccgacgcg gtgggctttt cctgctatat
    11701 ctggaatatt ctctatgtgc aggagctgat aagagatctg aaaaaggtgc tgccccagac
    11761 ggaaatctgg ctgggagggc cggaggtttc ctaccgggca gaggaatttt taaggaagga
    11821 accatcggcg cgcggcgtta tggccgggga aggggaggag acctttttcc ggcttctggg
    11881 cgctgcaaaa agacaggatg ccggatcgtc cgtctggcgg gacgaggcct tggaacagat
    11941 cccgggcctt gtgtttcgaa gagaggctgg aagcggaagc agcagcggcc ctgaaacagg
    12001 agagattgtg aaaaatccgc ctgcgccgct gatggatttg gacgatattc cctttgtcta
    12061 cagtgactta agaggcatgg agaacaggat tatctactat gagagcagca ggggatgtcc
    12121 cttttcctgc agctactgtc tttcttctat tgataagatg gtgcggtttc ggagtctgga
    12181 tcgggtgaag tgggagctgg cctttttcct ggagaaccgc gttccccagg tgaaattcgt
    12241 ggatcggacc tttaactgca aaaagagcca ttccatggaa atctggcgtt ttatccagga
    12301 acacgacaat ggaatcacaa attttcattt cgagatttca gcagatctgc tgtcggagga
    12361 ggagctttct ctgctgtccc agatgcgccc cgggctggtt cagctggaga ttggcgttca
    12421 gactacgaac ccggacacga tccgggagat caggcgtcgg atggatctgg gaaaactgga
    12481 gtctcacgtc aggcagatca acgggtttgg aaatatccac cagcatctgg atttaatcgc
    12541 aggactgcca tgggagggat acgagtcctt taagcgttcc tttaaccagg tttacgccat
    12601 ggagccggaa cagctgcagc tgggctttct gaaggtgctc tccggctcct atatggagga
    12661 gagggcgcag gactacggcc ttcgattcag agacacgcct ccctacgagg tgctggccac
    12721 cagatggctg tcttatgggg agctgatccg gctgaagggc gtggaggaga tggtggaaat
    12781 ctactacaac agcggccagt tcagaaacac tgtgaaggag ctgcagaagg agtttttatc
    12841 gccctttgac atgtatgagt ctctgcggga atactacaga gaagagggac tttcggcggt
    12901 cagccacagc aggaacgcca ggtacgagat tctctttgcg tttattgaga aaacgttggg
    12961 gaagagacct cagacaggcg tgcagaccag cgctcagaca gagggccaga cagaagaaca
    13021 ggcagaagac cggacagagg aaccggcaga ccggctggag ctgtaccggg atctgctgac
    13081 agaggatctt taccttcgcg aaaacgccaa gagccgcccc tcctttgcga gagatctgtc
    13141 tcccttcaag gaggaaataa agcagttctt tatcagagag ggaaaggaac cgtgccgtct
    13201 gacaggatat gaagggtatg attccaggca gatgagccgg atggcccaca tggaagttat
    13261 gcgggacggc cggatgctgc tgtttgacta tctgtgccgg gacgcgcttc tcggaaatgc
    13321 cagaaccatt gaggcaggca gaatcagggg ggataacgaa acggcagagc cgggcgaaag
    13381 aaggaagcaa aagatcattt atcattttta cgaaaaaggg gaacaatagc tgtgagacga
    13441 gagacgaagg cccagaaggc ggagcgggtg aagagaatcc ttgagctgct tgaccaggaa
    13501 tacggcacag agtaccgctg ctacctgaat cacgagacgc cgtggcagct cttaatcgcc
    13561 gtgattatga gcgcccagtg tacggacgcc agggtaaata tcgtgacgga gactctgttt
    13621 aaaaaatacg acacgctgga gaagtttgcc gccgccgatc agagggagct ggagcaggat
    13681 atccactcca tcggctttta ccattccaag gcgaagaata tcattgcctg ctgtcaggcg
    13741 ctggtggagc ggtttggcgg ccaggttccg gaacggatgg aggatctgct gactctggca
    13801 ggagtgggca ggaagacggc caatgtaatc cgcggcaata tttacaatga acccagcatt
    13861 gtggtggaca cccacgtaaa gcggatttcc agaaagctgg ggcttgcgaa ggaggaggac
    13921 ccggagaaaa tcgagtatga gctgatgaag gtgctgccaa aagatcactg gattctgtgg
    13981 aatatccaca ttattacact gggaagaacg atctgcacag ccagaaaccc cagatgccgg
    14041 gactgctttc tgagggagga atgccctgga aaagaggcgg agctgtgatg gaagagaaaa
    14101 gaaaagagac gcctgatcag gtgggaaact cctatctggc gctggatctg gagactacag
    14161 ggctggatcc gaagcgcgat aaaatcatag agattggagc ctgtcgcgta agggacgggg
    14221 agatagagaa ggagctttcc ctgcttattc atcctcacca gccccttccg gagcggatca
    14281 cagcgctgac aggcattacg gacgaaatgc tttcggaggc gccggacatg gagtctgtca
    14341 tcggccaggt gatggacttc tgcggcgatc ttccgattct gggccatcat gtgatctttg
    14401 attacagctt tttaaagcgg gccgcagtca acgcaggctt tccctttgag agaacgggca
    14461 ttgatacgct gggactctgc cgccggttta tgccagagga ggagaaaaag aatctgtccg
    14521 ccgcctgcgc ctggtatcag gttccggagg agacggccca ccgggcgctc tcagacgcca
    14581 gaatggccca tttcctgtat cagaaaatca gggctctgaa catttccgga catgaggaga
    14641 cttttttgcc aaagcccctg atttataagg taaaaaggga acagccggcc tcaaaaaagc
    14701 aaaaagaagg cttgcgggaa ttggcaaaat atcatagaat aaacctatct gttgacatag
    14761 aatacctgac gcgcagcgag gcgtccagga tgacagataa aatcatattt cagtacggaa
    14821 gaatgaaaaa gaggtgagag acgtatgttt atgggaaata ataagtcaaa gaagattatc
    14881 actacgatta tggttgtgat cattctcata accatggtag gaggaactgt gatcgcaggc
    14941 ttatcctcct tattttaggg aagaggagtt ttccagcgta tgaagaggaa tttatggaca
    15001 gccggtctga cagcagctct gtcagccgga attttattta tgcagcctgt gatcgcggag
    15061 gcgggaatcc ttccggaggg attttctgtg gcgggggcag gagacgaggc tcttgatttt
    15121 tccgggcaga cggcggagga ggcctccggg aagctggagg agtatgtagg atccatggcg
    15181 gaggagaaga tttccatctc catcgacgga accagctttt cctccacagc cggagatctg
    15241 gggctctact gggaaaacaa agaggagtta aacgccgcta ttggggagta ttccggagga
    15301 aatcttctgg agcgcttcgc gcggacgaag aagcttgaga aggaaccgct ttccctggct
    15361 gtgaaggctt ctctggacga tgaaaagctg tcggcctttg taaacgacaa ctgcgcgccc
    15421 tatgtgcggg aggcgaggga cgcgtccatt tccagagaga acggcgcctt tgtcattaca
    15481 gacgaggaaa ttggactggg agtcgatttc gaggccacca gagaggctct gaatactgcc
    15541 ctgaaccagg gaatttccga ctccatctct gtggaggcag tggtgacgga ggcagagccg
    15601 agaatccaca gatcggatct ggagagcatt tcagatgtgc ttggaacctt cagcacgaat
    15661 tttaacgcgg gagaccgctc cagaacccag aacctgaaaa cgggagccgg aaagatcaac
    15721 ggcacggtgc tgatgcccgg agacgaattt tcagcctata cctggctgac gccgtttacc
    15781 attgagaacg gatatgcggc cgctggatcc tacgagaacg gccggacggt ggattctatc
    15841 ggaggaggcg cctgccagct gtgtaccacg ctctataacg tggttcttcg ggcagagctt
    15901 gaggtgacgc agaggcagaa ccattccatg actgtgggat atgtgaagcc ctctgaggac
    15961 gcggccattg cgggaaccta caaggatctg aagtttaaga ataactacga cacgccgatc
    16021 tatcttgaag gttctgtcgc aggaaacacg ctgaccttta cggcttacgg aaaggacacc
    16081 aggccggagg gaagaacggt agagtttgtt tccgagacgc tgggaacgac agatccgggc
    16141 gctccggtag aaaagccgga tccgtccctg gctccggggg ccagagtgaa ggagtcctcc
    16201 ggacacgttg gaaagaagtc gagactctgg aaggtagtct atgaaaacgg agtggagacg
    16261 ggacgggaaa ttctccacac agacacctac atggcgtcaa aggccgtgta ccgggtaggc
    16321 ccggcggctc cgtccgtgcc ggctgttacc gaaccgtcga ctccggcaga gacgcagcct
    16381 caggagaatg ctcctgtaca ggaacagccg tcaggtcccg caggacctgc ctcagagcct
    16441 gtaagccctg ccgctccggc ggcggatccg gcttctgtgc cggctccaag agcgccggcc
    16501 tagaaaaggc ccataggagg agcgcatgaa cagacatttg aatcaggaac aggagaaaag
    16561 gcccggctca ttgaagccgg gccaggatct tatcatagcc ggaagcatcg gtctcacggg
    16621 ggcagctctg gccgccagag cgggggagaa ggccgtcaga gagcgctttt cgagccagta
    16681 tgcagagcgg atttttactc tggatcaggg acttctgtct caggaggagg cagaagagat
    16741 cggcagattg gcgggagcca cagatatgga gccggtggga gagggcggtt ttatgaactg
    16801 tctctggcgg cttctggagg cctatggctt gggctgcatc atcgagctcc gcgctatttt
    16861 gcttcgccag gagacagtag aggcctgcga ggtctttgac ctgaatcctt accggctcca
    16921 ctccgccgga tgctttctta tggcggcaga cagcggcttt gaagcggtga gagagattga
    16981 aagaagaggc tttgagggcg cggtaatcgg cgccgtaaag cccggcccgg cccgacgcat
    17041 tttaaatgga gagattgaga cctttctgga tcgccccaag gctgatgagc tggaaaaatt
    17101 aggattatta aaataatttt aaaaatttcg gatatttcaa aaattacaaa acaacatata
    17161 aaacgcatca tgatattcaa tgactataat ggcagaacaa gcataagaaa tcagaaggag
    17221 gcagcggtat gagagaacga attttagcag tcatcgaaaa aaacagccgg atcagcacag
    17281 cggagctggc ggaaatcctg ggggagaatg aagcggcggt ggcggcggag attgccgaaa
    17341 tggaagagga acacattatc tgcggctacc acaccctgat taactgggac aacacagagg
    17401 atgagaaggt gatcgcgctg atcgaggtga aggtgacgcc gcagagacag atgggctttg
    17461 aaaagatcgc ggagcgcctt tctctctaca gcgaggtaaa ggctgtgtat ctgatgtccg
    17521 gcgcctttga ttttactgtg attattgagg gcaagagcat gcgcggcgtg gcccagttcg
    17581 tatcggagaa gctggctacc attgactctg tcatcagcac ggccacccat tttgtgctga
    17641 aaaaatataa ggaccacggc acagttttaa acgacggccc ccaggatgaa aggatgttga
    17701 ttaacccatg agaaacccct tatcaaacac gattgtaacg attccgccgt ccggcatcag
    17761 gaagtttttc gacattgtaa gcgagatgga gggagccatt tccctgggcg taggcgagcc
    17821 ggatttcgac acgccctggc atgtgaggga cgcgggcatc cgctccctgg agatgggaaa
    17881 aaccttctac acctccaacg caggccttaa ggagctgaag caggagatct gcaattatct
    17941 gaaacggcgg atgcaggtgg agtacgatta caatacagag gtgatggtga ccattggcgg
    18001 cagcgaggcc atcgacgtag ctctgcgggc tatgctggat ccgggcgacg aggtgctgat
    18061 tccccagccc agctacgtat cctacgttcc ctgcaccatt ttagccggcg gcgttccggt
    18121 ggtgattgag ctggaggaga aggatcagtt ccgcctgacc agggagaagc ttctggagaa
    18181 gatcacagat aagacgaaag tgttagtgct tcccttcccc aataatccta caggagcgat
    18241 tatggagcgg gaggatctgg aggcagttgc aaaggtagtg gaggagaagg atctcttcgt
    18301 catcagcgac gagatctatg ccgagctgac ctataagaaa aagcacatga ccatcgcttc
    18361 cctgcccggc atgagggaga gaactgtatt gatcaacggt ttttccaagg cctatgccat
    18421 gacgggctgg agaatcggct acgcctgcgc gccggccctg attttaaagc agatgttaaa
    18481 gatccaccag tacgccatca tgtgcgctcc taccaccagc cagtacgcgg cggtggaagc
    18541 cgtgaagaac ggggacgctg atatcgagga gatgaagcgt tcctacgacg aaaggcgcag
    18601 atatctgtta aaggaattcc gctctctggg gatggactgc tttgagcctt acggcgcgtt
    18661 ctacatgttc cccagcatta aacggttcca catgacttcc gaggagtttg ccaccaggct
    18721 gctcagggaa gagaagattg ccattgtgcc gggaacggcc tttggagact gcggagaggg
    18781 gtatctgaga gtttcctacg cttactccct ggaggatctg aaacgggcaa tccgcagaat
    18841 ccgccggttt gtgaaccgcc tggacgagga gaatggcgca ggagagaaga gcgggcagcc
    18901 agaccaggaa gaaaagagag ctggaaagca aagataggga aagaggttga cataagatga
    18961 acattgtgct gtatgagccg gagatgccgg ccaataccgg aaatattgga agaacctgcg
    19021 tggccacggg aaccaggctg cacctgatag agccccttgg atttaagctg aatgagaagg
    19081 cgttaaagcg ggcggggctg gattactggg acaagctgga cgtgacagtg tacagcgatt
    19141 ttcaggattt tctggacagg aatccaggcg cgaaaatcta tatggcgact accaaggcgc
    19201 cgaacgtgta cacagaggct tcctatgagc cggactgcta catcatgttc ggaccagaga
    19261 gccgcgggat tccggaggat atcctggtaa accatcagga aacctgcgtc aggattccca
    19321 tgtggggcga tatccgctct ctgaatctgt ccaattctgt ctccattatc ctctatgagg
    19381 cattgagaca gaacggattt gagaaaatga cgatgcaggg acatttgaga aactacgact
    19441 ggcagtaaaa atagaagaca ggaggaaatg ccatgattct tcagagtacg cgcgtctggg
    19501 cggcgggaca gtttctgccc cttcagcttc agatcgaggg agacaagatt gttcaggtat
    19561 tggaatacaa aagccaggag gcggacgagg actggggcga taagcgcatt gtcccgggtt
    19621 tcattgacgt ccacacccac ggagcctatg gcttcgatac caacgacgcg gagccggaag
    19681 gtcttaagga ctggatgaga cggattccgg aggagggagt gacctccatt ctgcctacca
    19741 cggtaacgca gatgccggag gtgctttcag ccgcagtaaa aaacgtggcg gacgtggcag
    19801 agggagagta cgagggagcg gagatcctgg gcatccactt tgaggggccg ttcttagaca
    19861 tggagtacaa gggggctcag ccgccggagg ccattgcggt tcccagcgtg gagcagttta
    19921 agaagtacca ggaggccgcc agaggccata tccgctatat tactctggct ccggagcacg
    19981 atccgggact ggccctgacc cgctacctga agcagacagg cgtggtagtc agcatgggcc
    20041 attcctgcgc gacctacgag caggccatgc tggccattgc caacggggcc tcctctatga
    20101 cgcatgttta caatggaatg acagccttca cccacagaaa gccggggctg gtgggagccg
    20161 ccttccgggt gagagatatt tacggagagg tgattgcaga cggacaccac tcccacgtat
    20221 cggctcttaa taacttctac cagctgaagg gccgtgactt cgccatgatg gtgacagact
    20281 ccctgagagc caagcactgc ccgccgggag gaaagtacca gctgggcggc catgacatcg
    20341 aaatcactgc ggagggactg gcctacctga agggcacgaa tactatcgct ggcagcaccc
    20401 tgcacatgaa ccggggcctt cagattctgg tggagaaggc catgattcca tttgattcag
    20461 cccttaattc ctgcaccatc aacccggcca gatgcctggg cgtggacgac aggaaaggaa
    20521 agatctgcgc tggatacgac gcggatctgg tggttctgga ggacaattac gacgtggccc
    20581 agacctactg ccgcggcaga aagatgctgt aatttaccag aaataatcag ataataatag
    20641 gaagagtctg cggtaaaaga gactgtacat gaaaagaggc tgtatgttcc ggaaccattg
    20701 tggtgcactg gaagatacag cctctttttt attgaaattc aaactgcaat cgaatggcaa
    20761 aatcagatga tttagaatac gcccttttct tttgccaggg acagggcctc tgtatctgcg
    20821 ataatcacag cgtcaggatg aagctgaagg acagacgccg gcacgtgagg agtcacaggg
    20881 ccgaagcatg tatcgaagat agcctgagcc tttccggtgc cggaagctaa aagaaggatc
    20941 ttcttggcgg ccatgatatt tccgattccc atggtgtagg cctgcttcgg aacctcgtcg
    21001 atggaggaga aaaatctggc gttggcctcg atggtgctct gtgtcagatc cacgcagtgg
    21061 gttcctacta cgaactcgcc gcagggctcg ttaaatccga tgtgtccgtt tccgccgatg
    21121 cctaacagct gcaggtcaac gccgcccata gagagaatct gcgcgtcata gtctgcgcag
    21181 gccttgtcgg agtcaggctc ttttccgttg ggcacatgag tacgggcctt gtcgatgttt
    21241 acatggtcaa acaggtgatg gttcataaaa tagcggtagc tctggtcgtt gtcctcggag
    21301 agacctctgt actcgtcaag attgacagag gaaacctggg agaagtccag aacgccctgc
    21361 tcaaaacgtg ttaccagctc cttgtaggtt ccttccggag tagatcctgt ggcaagtccc
    21421 agcacacagt ctggctttaa aatgacctgg gcagcaatga gatcagcggc cttgcggctt
    21481 aagtcttcat aattcgcagc ttcaataatt cgcataatca attctccttt atcatttaat
    21541 tgcccatccg gcaggaagaa gaataaaacg gaaatctccg ggcaggatgc gcgtttgctt
    21601 tcctattata atcgattttc acagggtttt tcaatgcctg gaagaaaaca aatgggcaga
    21661 ttcgtgattg tatgcgatta agaacttgcc attgacgggg aatatgcgtt atattcttaa
    21721 cgataaaggt gggaataaaa cgcggacagc gtttttactg aaatagatcc cagacaaaag
    21781 tatagaaaag agaggttaca gtatgagagg agtagagaca cgaatccagg aaatccgtca
    21841 ccgaattttc cgtgaggtgg cgcgtatggc ctatcacaca gagtggccgg tagataagag
    21901 aattgaggag cttccatata agattattcc gggagaggtt ggaaacttca gaaacgacgt
    21961 tttcttagag agagcgattg taggagagcg tttaagactg gctatgggcc ttccgtgcag
    22021 aggcgcggca gagcacgctc cgttatccga caatatcgag gcggcagaca aggcagagac
    22081 ctactacacc ccgccgttaa tcaatgtaat taagtttgcc tgcaacgcct gccatgagaa
    22141 gcgcgtgtac gtgacagacg gatgccaggg ctgtctggct catccgtgcg tggaggtctg
    22201 tccgaaggga gccgtaactc tggacagaac aaacggccgg tcctacattg atcaggacaa
    22261 gtgcatcaag tgcggaaagt gtaaggatgt ctgcggatat aacgcaatta tcgtgcagga
    22321 gcgcccctgc gcggcagcct gcggtatgga cgccatccac tctgacgcaa acggaaaggc
    22381 cgagattgat tatgagaagt gcgtttcctg cggacagtgt cttgtaaact gcccatttgg
    22441 cgcaattgca gataaatctc agattttcca ggtaattcgt gcaattcagt ccggagagcg
    22501 cgtatacgcg gcggtagctc ctgcgttcgt aggccagttc ggacctaagg tgactccagg
    22561 aaagatgcgt gcggctatga agcagctggg ctttgcggat gtattcgagg tggctatcgg
    22621 agctgacctg tgcgccacac aggaggccat tgactttatg aaagaggttc caaacgagat
    22681 tccgtttatg gcgacctcct gctgtccggc atggtccatg atggctaaga agctgttccc
    22741 agagcaggcc aactgcattt ccatggccct gacgcctatg actctgacag ccagactgat
    22801 taagagcaag cacgagaacg ctaagattgt atttattgga ccgtgcgcag ctaagaagct
    22861 ggaggctatg agaagaagcg tgcgcagcga ggtagatttc gtactgacct ttgaggagat
    22921 ggctggaatc tttgacgcga agcatgtgga tatcgagaac atggaggaag atccggacgg
    22981 cgtaaacgac gcttccacag acggccgtaa ctttgccgta gcaggaggcg ttgcccagtc
    23041 tgttgtaaat gtaattaaga agagattccc agagagggag atcaagattg ccaacgcaga
    23101 gggcttaaag gactgccgca agctcttaac tcttgccaaa gcaggaaaat acaacggcta
    23161 tctgttagag ggtatggcct gcccaggcgg ctgcgtagcc ggtgcgggaa ccatgcagcc
    23221 gatcaagaag tcccaggctg ccgtaaagca gtacgcgtcc aaggcacagc atgcgacgtc
    23281 cagcgagaca gagtatgtaa aagagctgga taagctggtt gactaatgaa acgaaatgtc
    23341 tgaggaaaaa ttttcttgtt ccaattaaag tcaccgaaaa tttttcctcg ggcataaagg
    23401 cgtatacaga ctgtatttcc ggcatgacct gcgtatgtat gaaatctgcc ggccattgac
    23461 tttcctgtgg ggattgctta tactgatgtt agcgtcagtg tataaagagc aatacagcgt
    23521 gttgttcctt ctacactgac gctaaattcc ttgaaaggag acagatgtat gaaaatagca
    23581 attccatatg cggaggagca ggtatttcag catttcaatg aagcttctca gtttaagatt
    23641 tatacagtgg acgagtttga tattctagag gaggagctgg tatccatttc ccaggacacg
    23701 cctgcgcaga cggcggcagc cctgaaagct cagggagtca atgtggtgat ctgcggcaac
    23761 atcggcgtgg cttccctttt aaatcttcag gacgctaaga ttcaggttat gggcggcgcc
    23821 tacggggcgg ccagagaaca ggtagaaaag ttcttaaacg gccagcttca cttcgagaca
    23881 aaagagagca gaagccagca gcagtccggc gagagcaatg gaaacgtgag tgcctgcggg
    23941 aatcagtgct tttagagagt aaagctaaaa atccagtttt tcagttccac taaaagctta
    24001 gtcactgaaa aactggattt taatcccacc aacaataata aacaaaacaa tcatcgccaa
    24061 atagctttac acttggaatt agtttaccat tattatcaat aagaaaagtg gattgcgaaa
    24121 aatctgttac ttctctaata tcgcttggaa atatatcttt cggttcatta aaaatttgtt
    24181 ttatctcata aagagataat ttgctgaaaa taatcaaggt gtcagcagta atacactgct
    24241 cattattatc ttcttccaat ccatagactt gtacaaaaat ttttgcagtt tcatctatgc
    24301 taagtaattt ttcaatcaaa gtaatgtatt tttgtttccc ttcaagacgt tcacatgaga
    24361 aatctgtaaa atcatccgtt gggtctaaga aatccttgta tgaaaaccac taattatttg
    24421 tataatttct attcgattca tcaattttca gcaatgttaa aattgtgccc ttttgttggt
    24481 tattcatgtt atttccctct taaaaattac cgatttttct atttctctac aaattccgag
    24541 ttatcgcttt atccaactcc ccgataaatg gcatttcatt cttctatcca agatttgaat
    24601 atttctaaaa cagttactaa attattggga ctacaagcag ctgaaaaaat tttattagta
    24661 actttacaat gtaaccagct catatcattt tcaaagtcct gat
//
LOCUS       DBMDUW010000036        24608 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1366_length_24608_cov_3.279104, whole genome shotgun sequence.
ACCESSION   DBMDUW010000036 DBMDUW010000000
VERSION     DBMDUW010000036.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 24608)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 24608)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24608
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1366_length_24608_cov_3.279104"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(72..1082)
                     /locus_tag="ACZPCR_07945"
     CDS             complement(72..1082)
                     /locus_tag="ACZPCR_07945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGGtGRT protein"
                     /protein_id="HIR1230842.1"
                     /translation="MALFESYERRIDKINSVLNSYGIASIEEAEKITKDAGLDVYNQV
                     KGIQPICFENACWAYITGAAIAIKKGCRKASDAAAAIGEGLQAFCIPGSVADQRKVGL
                     GHGNLGKMLLEEDTDCFCFLAGHESFAAAEGAIGIAEKANKVRKKPLRVILNGLGKDA
                     AQIIARINGFTYVETQYDYYTGELKEVFRKAYSDGPRAKVNCYGANDVREGVAIMWKE
                     NVDVSITGNSTNPTRFQHPVAGTYKKERVEAGKKYFSVASGGGTGRTLHPDNMAAGPA
                     SYGMTDTLGRMHSDAQFAGSSSVPAHVEMMGLIGAGNNPMVGMTVAVAVAIEEAAEAG
                     KF"
     gene            complement(1155..1847)
                     /locus_tag="ACZPCR_07950"
     CDS             complement(1155..1847)
                     /locus_tag="ACZPCR_07950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003021275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster assembly scaffold protein"
                     /protein_id="HIR1230843.1"
                     /translation="MIYSHEVEKMCTVAQGVCHGAAPIPEEAKWVQAKEIKDISGLTH
                     GVGWCAPQQGACKLTLNVKDGVIQEALVETLGCSGMTHSAAMAAEVLPGRTILEALNT
                     DLVCDAINTAMRELFLQIVYGRTQSAFSEDGLPIGAGLEDLGKGLRSQVGTMYGTLKK
                     GPRYLEMAEGYVTGIALDAEDQIIGYQYVNLGKMTDFIKKGDDPTTAYEKAKGQYGRV
                     ADAVKIIDPREE"
     gene            complement(1937..3298)
                     /locus_tag="ACZPCR_07955"
     CDS             complement(1937..3298)
                     /locus_tag="ACZPCR_07955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1230844.1"
                     /translation="MKKQVDLLHGKIVSSLTELALPIMGTAAVQMAYNLTDMAWIGRV
                     GASAVASVGAAGMYTWLSNGPVMLAKMGGQVKVAHSLGEGRSERAAQFGKGALQLTVF
                     LAVLYGLIMNLFTHRLIGFFGLGDPKIIGDAVIYLRIAGGLIIFSYLNQTLTNLFTAI
                     GNSRVPFAANCIGMLSNIVLDPMLIFGIGFFPRMGVAGAAAATVASQAVVTSVMLWHV
                     KKDTILFDKIRFWEKTPLPYFISMIKIGFPSAVQESLYCGISMILTKFVTGWGDTAVA
                     VQRVGGQIESLSWMTAEGFGMAINAFVGQNYGAKQYGRMKKGYFIAAGMMTAWGALIT
                     VIMLTFSTPTFGLFIHEADVLPYGADYLRIMGVGQIFMCVELMTVGALAGMGKTLYSS
                     IISILLTSARIPLAMALGSTALGLDGIWWALTISSILKGITFFLVCCMVFRKITPFLR
                     PSD"
     gene            complement(3480..4886)
                     /gene="gltA"
                     /locus_tag="ACZPCR_07960"
     CDS             complement(3480..4886)
                     /gene="gltA"
                     /locus_tag="ACZPCR_07960"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004355 - glutamate synthase (NADPH)
                     activity [Evidence IEA];
                     GO_process: GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HIR1230845.1"
                     /translation="MEANRDMMKRVPVREQDPKERATNFKEVCLGYDMDEAMAEAVRC
                     LNCKNAQCVKGCPVSIDIPAFVQEVKEGNIEKAAEIIAKSSALPAVCGRVCPQESQCE
                     GKCIRGIKGEPVSIGKLERFVADWAREHGFVPKAAEEKNGKRVAVIGSGPAGLTCAGD
                     LAKLGYEVKIFEALHEAGGVLTYGIPEFRLPKSGVVQPEIDNVRKLGVEIETNVVIGK
                     SVTIDELMEKEGFDAVFIGSGAGLPKFMGIPGENSNGVFSANEYLTRSNLMKAFRDDY
                     DTPIAAGHKVAVVGGGNVAMDAARTALRLGAEVYIVYRRSEKELPARVEEVHHAKEEG
                     IQFHLLTNPVEILADEQGWVKGIVCRKMELGEPDESGRRRPVEVEGSDYTLDVDTVIM
                     ALGTSPNPLISNTTKGLEVNKWKCIVADEANGKTTKEGVYAGGDAVTGAATVILAMEA
                     GRAGAKGIHEFLSGAKAE"
     gene            complement(4886..5776)
                     /locus_tag="ACZPCR_07965"
     CDS             complement(4886..5776)
                     /locus_tag="ACZPCR_07965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HIR1230846.1"
                     /translation="MYQILKAEKLADKIYLMDVKAPRVACACEPGEFVIVKMDEEGER
                     IPLTICDFNREEGTITIVFQTVGASTEKMAELKAGDAFRDVVGPLGNASDFVKEDVAE
                     LKNKKYLFVAGGVGAAPVYPQVKWMHEHGIDVDVIVGSKTKDLIILEEEMKAVAGNLY
                     ITTDDGSYERKGMVTEVIKDLVQNQGKKYDVCVAIGPMIMMKFVCLLTKELGLPTIVS
                     LNPIMVDGTGMCGACRVTVGGKVKFACVDGPEFDGHEVNFDEAMKRQQMYKTEEGRAL
                     LKLREGDTHHGGCGHCGGND"
     gene            complement(6118..6603)
                     /locus_tag="ACZPCR_07970"
     CDS             complement(6118..6603)
                     /locus_tag="ACZPCR_07970"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HIR1230847.1"
                     /translation="MQLIAAVDKHWAIGKNGQMLAVIPADQKLFRQETIGKVVVMGRK
                     TLESLPGGRPLESRTNLVLTRDPSFKIKGAVTVHSMEEALSELSKYRDEDIFIIGGQT
                     IYEQFLPYCQEAHITFIDYEYNADTYMVNLEQEGWIVTDCSDEQTYFDLCYEFRRYVR
                     P"
     gene            complement(6594..7787)
                     /locus_tag="ACZPCR_07975"
     CDS             complement(6594..7787)
                     /locus_tag="ACZPCR_07975"
                     /inference="COORDINATES: protein motif:HMM:NF012955.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6506 family protein"
                     /protein_id="HIR1230848.1"
                     /translation="MKFAFLILGDFRATEDRAEIHHGSARMIGVSTLDEACQAARELY
                     EEGVGCIELCGAFGPDGARRIIEVTENKIPVGYVTHLPEQEEIYQAAFSDKKAETVKI
                     IDVTGVGEGAVFLLRGRANILFEAGMAYAADAMIEKIKQELQGEPLHAVLLSHSHYDH
                     VAGLPAVRKEWPDVKVYASERAKEILVKPGALKTIRRLSGEAAEASGLSWDSAYDDRD
                     IQADIGLKDGETTEISGDQVYAFATPGHTKCSMSYVINGEVMLCSETVGVMNRNQEYM
                     PSFLVDYKGVEDSIRRSAEIPVREIILNHYGLVEEKDKAGIWEFLLETARKSRDLMLD
                     ILNETDSDEEALRTMERTFHSTVDKKDQPDEAFYINAASMIKTLRRQYPEKIREDRRE
                     SEVCS"
     gene            7952..8575
                     /locus_tag="ACZPCR_07980"
     CDS             7952..8575
                     /locus_tag="ACZPCR_07980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006781066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230849.1"
                     /translation="MITLERTSVMNLENAMRGARNPMNSWHRSDSCYDENGSYLLGPN
                     DLDLAKRLRQAGSDHRKYVRQIFVSVDITAPLYWWKEYDTYKVATVANSCSTMHKIHS
                     KEFTMDDFSCDHMTDGARAFMQTIVDKLEETRKRYLETKNKEDWYDLIQLLPSSYNQM
                     RTCTFNYETLINIYYARKDHKLAEWHTFCDWILTLPYAKELIVGEGK"
     gene            complement(8716..10119)
                     /locus_tag="ACZPCR_07985"
     CDS             complement(8716..10119)
                     /locus_tag="ACZPCR_07985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HIR1230850.1"
                     /translation="MFSEIINTLSNWLYTYILIVLLLGAGIYFTVKTKFIQFRCLKEA
                     IRVVKEPSDDKESISSFQALMVSTASRVGTGNIAGISTAICIGGAGAMFWMWLVAILG
                     SASAFIESTLAQIYKRKAADGSSYGGPAYYIQAVLKKRWLGILFAGTLIVTYMGGFNM
                     VAAFNIADSFRAYSFYDPSTTPLIIGAVLAAAFAVCIFGGSKQISKITGVLVPVMGIF
                     YILVSLVIIVTHLNLVPQMFADIFTQAFDFKAIFGGFTGSAIMQGIKRGLFSNEAGVG
                     SAPNAAASAGVSHPVKQGLVQMLSVYIDTIVICSATAFMLLCSGIEPSTDLQGMPYVQ
                     AAVANTLGSFGTIFITIALVLFAFTTLIGNFYYAEMGLGYICDKTPNKALLMVFRLAA
                     ALIVCFGATMEFSVAWNTADVLMGLMAIINLPVILILGGPAVRCMNDYLKQKKEGKNP
                     VFKAKDIDLETKTDFWN"
     gene            complement(10387..11319)
                     /gene="glsA"
                     /locus_tag="ACZPCR_07990"
     CDS             complement(10387..11319)
                     /gene="glsA"
                     /locus_tag="ACZPCR_07990"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004222609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HIR1230851.1"
                     /translation="MTDKERGRILEEALLAGSMEVDKGETASYIPELSRADKHDLGIC
                     IYTRDGEIYEAGDSQKRFTIQSISKVISLCVALQHCGFDKVFEKIRMEPSGDAFNSLL
                     KLDMTSNYPYNPMINSGAITVVSYLMPIFSFKELLDYAGKLCLDPKIRLDERAYTSEM
                     ANSARNRAIAYLLQSKGIIECDIERSLELYVKMCSLSVTAKSLAAFGLVLANGGIHPE
                     TGERLLDREVVRTVKTIMLTCGMYDGSGEFAVEVGIPSKSGVGGGILSVVDRKMGIGI
                     YGPSLDKKGNSIGGKAMLKYVSEELNLHMFAWEP"
     gene            11611..12561
                     /locus_tag="ACZPCR_07995"
     CDS             11611..12561
                     /locus_tag="ACZPCR_07995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008395029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HIR1230852.1"
                     /translation="MDYDINLKHLSYFITTARLGSINRAAQTLYISQPHLGKIIKELE
                     RTAGTMLFERTRGGVILTPDGRDFLERAEGTLRAAQSLLEFRSASSPSAHSLMVSMTR
                     FSHIMECFIEIVLRHKNDDAFVHRLREGTADEVIEDVYSGQFHVGVIHFNPEEKKSVL
                     ARLASMGLSYETLSLVRPHIVLSRNHPLIREGKPVTLENLALYGFARYQDAAEDFAYH
                     IFSENILYNLNSGLKIVYLDGRASLLHLLANSDFYGIGIYGFSAQDSTYQVISIPIEE
                     CRDRLEFGYILPKGGPVSEITAEFIEELKNRFSKALSPQA"
     gene            complement(12536..16213)
                     /gene="addA"
                     /locus_tag="ACZPCR_08000"
     CDS             complement(12536..16213)
                     /gene="addA"
                     /locus_tag="ACZPCR_08000"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007868949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HIR1230853.1"
                     /translation="MGVNWTRDQRQVIESRHRNLLVSAAAGSGKTAVLVERIIEMITD
                     KEHPGDIERLLVMTFTKAAASEMRERILDAIEKKLAKEPDNEYLQQQAVLVQYAQITT
                     IDSFCLHLLGEHFDCLDLDPAFRVGDEGEMLLLRGDVMEELLEDWYGKKDPKFEEFVD
                     AFASGKADGGIDEYIYQVYSFSQSNPWPGEWIAQCRKELSDTSLEALDQTEWMRFLLA
                     DVKTQASEWVKELKAASGLCREPDGPEPYLPMILSDLAHAERMEQVSGYGMLAREADS
                     FEFPKLAAIRGKNSAVSPEKKEAVAECRKRIKKALEKIKAQFLFASEEEILSDLAGSR
                     DSILMLLSLAEEFEQRFSAKKRERNLVDFNDLEHLALQVLYRDSGELSETADDLARQF
                     DEILVDEYQDSNLVQEALIRAVSRERFGEPDVFMVGDVKQSIYKFRLARPELFLEKYQ
                     SYTREDSQFQKIELHQNFRSRPQVLESTNDVFFKIMTEKLGSVAYTEDAALHPGAGYE
                     PLPESASEEERDFSTELLLINTKDSILEELDDDSADYTRQELEARMIGMRIRELTDPE
                     KGCLVWDKEEGAYRRAEYRDIVILLRSVSGWAESFVETLGHMGIPAFAESKTGYFTTI
                     EVETILNFLAVLDNPMQDIPLAAVLRAPFFGLTDRELAEITAEFKSNTEKGQDRGLYG
                     AVCACLDTYRKENRCLEAEEGETARKLDFFTEVMEELRMQAVYLPIHELLYRIFDRTG
                     YYDYVSAMPSGETRRANLDMLVEKAAAYESTSYRGVFHFIKYIEKLKKYNTDFGEAST
                     AAEGGNTVRIMSIHKSKGLEFPIVFASAMGKQFNKQDTRGKILIDPQFGIGADYLDSE
                     TRLKASTLKKNVLKRRMDLENLGEELRVLYVAMTRAKEKLILTASDKNLESKLEKWKE
                     SLFETEGGLPFTLLSLASSYLDWILMAIAQGGCRIRVRETMAKELLGQEISRQVQQKL
                     TKDMLLGMDTSQKTLWEEALGLSDEAYRAQLEKLASCRYPWQDDLRLNTKLSVSDIKK
                     EGEEESLEESAFLPTIPKFLSDEKDEGQGARRGTAYHRAMELLEFHKIRTKQDIREQL
                     DRFAEEGRMTADDRALVRESVIWPFFQSDLGRRMADAQREGRLKKESQFVIGIPAREI
                     GDWDSDELVLIQGIMDAFFEENGELILVDYKTDYAEQEETLIERYKLQLDYYRRALMQ
                     MENKPVKETLIYSFRLGEIKL"
     gene            complement(16204..19656)
                     /gene="addB"
                     /locus_tag="ACZPCR_08005"
     CDS             complement(16204..19656)
                     /gene="addB"
                     /locus_tag="ACZPCR_08005"
                     /EC_number="3.1.-.-"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HIR1230854.1"
                     /translation="MSLQFIIGGSGSGKTHVLYENLIKCSMENPEGKFFAIVPEQFTM
                     QTQKDIVTMHPRHGVRNIDIVSFERLAYRIFEELAVETPAVLDDMGKSLVLRKVAAAR
                     KKNLRLFGSHLEQSGFIGELKSMLSELFQYGISGETIREMADSADSAMLRQKLSDMSE
                     LYEGFREYTRERFIAQEEILDILCRVLPKSRLIRGSVVTLDGYTGFTPVQYRLLELLL
                     TCCRQVVVTVTMPPEENPYREKPIQNLFHMSSHTVCRLTDLASGTGAGRDEDILLTGP
                     CRRFQNSPALSAIERGLFRPWAGRFEGAQGDSLLLHEAENPIGEIQFVCTEIQHLVKE
                     KGYRYRDIAVVTGALPDYSGELARQFQENGIPFFLDSKKNILSNPVVELLRAALETIT
                     ENFSYESMFRYLKTGMVTEEKEKLSRLENYVKAMGIRGFKRWSASWDRTYKDGERLNL
                     EELNEFKDSLLHPFLPLKEVFSDRQSTVREMTAALAEFLESVEAEKRLSRWEKAFHEM
                     GEAELEKEYSQVYGLVMDLFDRLAALLGDETVSRREYAQILDAGFAEIQVGLIPAVVD
                     RVVTGDLTRTRLSHVKALFFIGVNDGIVPGAARRGGILTEAERRILKERGVELAPTAR
                     EEGFLERLYLYLVMTKASDFLYLTWSQTSSAGKSLRPSSLIGQVKKLFPELRETRMDQ
                     YREAALSAPAGRRTLIAGLRDLEHAVSRPEFLELYRHFYTDEDKREETKRLVEAAFHV
                     YEDKGIGRTAAQKLYSPILRGSVTRMERYAACAYAHFLSFGLELRERREYELAAADLG
                     NLFHSSIDLFFKTMQEEGRSFRQLDDRERKELVSRCVSEVTREYGNTVVSDTARNEYL
                     GRRVEQITDRTVWALTEQLKKGDFEPAGFELTFTPADNLKAMKIPVSRTEAVHLQGRI
                     DRMDLCEDGDKLYVKIIDYKTGKTKFELTELFYGLQMQLVVYLDAAMEKEQRRHPDKQ
                     VLPAGIFYYNIADPMVEKTEDMSEEEKEAEILRTLRMNGLVNSRAEAISHLDRRIETE
                     SDVIPVAYKAGIIQEAKSSVANEKRFLAMTGFVNQKIKAMGREILDGRITVDPYKKGE
                     KTACDYCPYHGICGFDLKTKGYGFRRFKSMKPEAVWEEIEKSVEEDEQETLETEGGEA
                     AEWE"
     gene            19803..20255
                     /locus_tag="ACZPCR_08010"
     CDS             19803..20255
                     /locus_tag="ACZPCR_08010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007709159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230855.1"
                     /translation="MSSKTKIVVLRMKEIIYTAIFIGLGIILVTLLFIMFRPKKEPQT
                     VSSGQVQAAQASYTPGLYRASLSLGSQNADLEVAVDADHINSVSMTPLSDSVETMYPL
                     MAPALEQLSEQICSSQSLENLTYPEGSQYTCSALVQAIESCLLKASSQ"
     gene            complement(20326..21132)
                     /locus_tag="ACZPCR_08015"
     CDS             complement(20326..21132)
                     /locus_tag="ACZPCR_08015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002605628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HIR1230856.1"
                     /translation="MNSETSSEVLEKTALLQKMRSVPELFVLMSACTKEPYVECDAET
                     FDDEIFMFFTEDEAREKGKALLEEKIPVSIVRVEEKQKLLFFTSLFTMGINAIVMRNG
                     SENTRFQLEELVRRKKPEEQPEGTVWIENPQLHLTALYYAQEMRKQPNPQPDEKTSEL
                     LEELLADFKRGKYILALQKEEKGVPLAKLKDGQMYQPIFTDALEFQKFNRENKFRPVA
                     ADADKLAVLVAPEAKGVVLNIMSLNLPFNLNRKPAVPAEGDGGEKKSETV"
     gene            21373..23016
                     /locus_tag="ACZPCR_08020"
     CDS             21373..23016
                     /locus_tag="ACZPCR_08020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HIR1230857.1"
                     /translation="MEKMRPMLFTTWKTYSKEQFFKDLIAGIVVAIIALPLSIALALA
                     SGVGPEQGIYTAIVAGFVISLLGGSQVQIAGPTAAFATIVAGIVARSGMDGLAVATIL
                     AGIILILMGFCRFGSLIKFIPFTITTGFTSGIAVTIVIGQLKDFFGVVYPEGMPTIET
                     MEKLKAFAAGFVTLNMDAVIVGLVCLAILIVTPYFSEKIPGSLLAVIGGILMVKFLPL
                     NVNTIGDLYTISSALPSFHLPQLSFDMVQSALPDAFTIAVLAAIESLLSCVVADGMIN
                     GKHRSDMELAAQGAGNIASALFGGIPATGAIARTAANIKNGGRTPVAGMVHALVLVLI
                     LVVFMPYAGMIPMPAIAAILFMVAYNMCQWRTFAELVKTAPKSDIAVLIITFFLTIVF
                     DLVVAIEFGILLAGLLFMKRMSDVTEVHSWKYAEDEEEAEREKLRQLPPHINVYEISG
                     PLFFGAADEIGRIVARERATCLILRMRSVPSMDSTAMNAMNDLLKRCQKKGITLILSH
                     VNPQPMKVMEKAGYVDKVGRENFCENIDAAIAKAEELVK"
     gene            complement(23081..24238)
                     /locus_tag="ACZPCR_08025"
     CDS             complement(23081..24238)
                     /locus_tag="ACZPCR_08025"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0031388 - organic acid phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase family protein"
                     /protein_id="HIR1230858.1"
                     /translation="MKIVIAMDSFKGSLSSTEAAAAVREGIQASGMDAQIVIKPLADG
                     GEGTAAAFVEGMGAEEIQLTVTGPLGKPVKSSYAVLRETNTAVIETASAVGLTYIPSE
                     LRNPLYTTSRGAGELIRDALDRGLRKFVVGIGGSGTNDGGIGMLTALGFSFLDREGKE
                     TGCFGRDVAEIDRIDSSKADPRLSECTFQIACDVNNPLCGETGASMVFGPQKGATEEM
                     AEELDRALLHFSNLVKRDLGKDTADLPGSGAAGGLGYAFRTFLNGSLEPGISIIMEAV
                     GLEEELQNADIVITGEGRLDGQTAMGKAPVGVAKLAAEYGCQVIAFAGAVAPEARLCL
                     EQGIDAYFPIVRGPISREEAMEKERARRNMKETAEQVFRLISSVYKKQKND"
     gene            24384..24545
                     /locus_tag="ACZPCR_08030"
     CDS             24384..24545
                     /locus_tag="ACZPCR_08030"
                     /inference="COORDINATES: protein motif:HMM:NF017466.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar diacid recognition domain-containing
                     protein"
                     /protein_id="HIR1230859.1"
                     /translation="MKLSQHNACQIVTNINEIINQKMNLINANGIIIASTDESRIGTY
                     HAGAKKVNA"
BASE COUNT         5707 a         7029 c         5163 g         6709 t
ORIGIN      
        1 aaaaaagtac cgcaatcgct gtgattacgg tacttcctgg gtttaacgtc ttttcaattt
       61 gtaaagtcta tttagaactt tccagcctcg gctgcttcct cgatggcaac tgcaacagca
      121 acagtcatac caaccattgg gttgttgcct gcgccgatga gacccatcat ctctacgtga
      181 gccggtacgg aagaggaacc agcaaactgt gcgtcagagt gcatacgtcc taatgtatct
      241 gtcataccgt aggaagcagg acctgccgcc atgttgtccg ggtgaagcgt acgtcctgta
      301 ccgccgccgg atgctacgga gaagtacttc ttgcctgcct caacgcgctc cttcttgtaa
      361 gtacctgcta ccgggtgctg gaaacgtgtc gggtttgtgg agtttcctgt gatggaaacg
      421 tctacgttct ccttccacat gatagcaacg ccctcgcgga catcgtttgc gccgtagcag
      481 tttacctttg cacgggggcc gtcggagtat gcttttctga atacttcctt taactcgcct
      541 gtgtagtagt cgtactgtgt ctcaacatag gtaaagccgt tgattctggc aatgatctgg
      601 gcagcgtcct ttcctaaacc gtttaagata acgcgcagcg gtttcttacg aaccttgttt
      661 gccttctcag cgataccgat cgcgccctct gcagctgcga aggactcgtg tcctgccagg
      721 aagcagaagc agtctgtatc ctcttccaga agcatctttc caagatttcc gtggcctaaa
      781 cctacctttc tctggtcagc tacagatcct ggaatacaga atgcctgaag gccctctccg
      841 attgctgcag ctgcgtcaga cgccttgcgg cagcccttct tgatagcgat agccgcgcct
      901 gtgatgtatg cccagcatgc gttctcgaag cagataggct gaattccctt tacctgattg
      961 taaacgtcca gtccggcgtc cttcgtgatt ttctcagctt cttcgataga agcaattcca
     1021 tagctgttta atacggaatt gattttatca attcttctct catatgattc aaataatgcc
     1081 atgagtggtt ttcctccttg atatgtaatt aacaatctct ctgcaatttc acggttctaa
     1141 ctgaaacgaa ccaattactc ttctcttgga tcgatgatct ttacagcgtc tgccacgcgg
     1201 ccgtactgtc ccttagcctt ctcgtaagca gttgtcggat cgtcgccttt cttaatgaag
     1261 tcagtcatct tgccaaggtt tacgtactgg tatccgatga tctgatcctc tgcgtccaga
     1321 gcgattcctg ttacatatcc ctctgccatc tcaagatagc ggggtccctt ctttaatgta
     1381 ccgtacatgg ttccaacctg agagcggagt ccctttccca gatcctcaag tcctgctcca
     1441 atcggaagtc cgtcctcaga gaatgcgctc tgtgttcttc cgtaaacgat ctgtaagaac
     1501 agttctctca tggctgtatt gattgcatca catacaaggt ctgtgttcag tgcctcgagg
     1561 atcgttcttc ctggaagaac ctctgctgcc atagctgcgg agtgcgtcat accggagcag
     1621 ccaagtgtct ccaccagagc ctcctggatt acgccgtcct ttacgttcag agtcagcttg
     1681 caggctccct gctgaggagc gcaccagccc acgccatgtg ttaaaccaga aatatcctta
     1741 atctccttag cctgaaccca ctttgcctcc tccggaatcg gagctgcgcc atgacagaca
     1801 ccctgtgcaa ctgtacacat cttttctact tcatgtgaat aaatcattgt atgactcctt
     1861 tcaaacaagt gttttagtac attgttaatt ttatcacacc gtactaatcg tattatcgca
     1921 tggataagcc aattagtcaa tcagaaggcc gcaaaaaagg cgtaattttt ctgaacacca
     1981 tgcagcagac aagaaagaac gtgataccct ttaaaatgct ggagatggtc agagcccacc
     2041 agattccgtc gagccccaga gctgtggatc ccagcgccat ggccagcggg attctggcgg
     2101 acgtgagaag aatactgata atggagctgt agagcgtttt tcccatgcct gccagcgccc
     2161 ccactgtcat cagctccacg cacatgaaaa tctggccgac acccatgatt ctcagataat
     2221 cggctccgta gggaagcacg tccgcctcat ggatgaacag gccgaaagtc ggcgtgctga
     2281 aggtcagcat aatcaccgtg atcagggctc cccaggcagt catcatgccg gccgctataa
     2341 aatatccttt tttcatccgg ccatactgct tcgcgccgta gttctggcct acaaaggcgt
     2401 tgatagccat gccgaagccc tctgccgtca tccatgacag agactcaatc tggcctccga
     2461 ctctctgcac cgccacggcc gtatctcccc agcctgtgac gaatttggtg agaatcatgg
     2521 aaatgccgca gtagagggac tcctgcactg cagaaggaaa tccaatttta atcatactga
     2581 taaaataagg gagcggcgtc ttctcccaga agcggatctt gtcaaataaa atggtatctt
     2641 tctttacatg ccacagcatc acagacgtca ccactgcctg ggaagccaca gtagccgctg
     2701 ccgctccggc cactcccatc ctggggaaaa agccgattcc aaaaatcagc atgggatcca
     2761 gcacaatgtt gctgagcatg ccgatgcagt tggccgcaaa gggcacgcgg ctgtttccaa
     2821 tggcagtgaa aagattggta agcgtctgat tcagatagct gaaaataatc aggcctccgg
     2881 caattctcag ataaatcacc gcgtctccaa taatcttcgg atctcccagc ccaaaaaatc
     2941 caatgagccg gtgggtaaac agattcataa tcaggccgta aagcacagcc agaaaaacgg
     3001 tcagctgaag cgctcccttt ccaaactggg ccgccctttc gctcctgccc tctcccagag
     3061 aatgggccac cttcacctgt cctcccattt tagccagcat aaccgggccg ttggacagcc
     3121 aggtgtacat acctgccgcc cctacggacg ctaccgccga ggctcccacc cggccgatcc
     3181 atgccatatc tgtcaggttg taggccatct gcaccgctgc agttcccata ataggaaggg
     3241 ccagctccgt cagggatgaa acaatctttc catggagtaa atcaacctgt tttttcatcc
     3301 tgttttctct cctctctcct ttttctattc tccttttttc tgtttcactc ttctccggac
     3361 ctgaccggcg aagatacttt gaaaccaaag cggggcatga tatctgtcta tcatgcccct
     3421 ttactccggc cggacgcttc gccccggcct tctttttatt tgttatttta aattcaagac
     3481 tattctgcct tagctccgga caggaactcg tgaattccct tagctccggc gcggcctgcc
     3541 tccatggcaa ggataacggt tgctgcgcct gttacagcgt ctccgccagc gtaaacgcct
     3601 tccttggttg tctttccgtt cgcctcgtcc gctacgatac atttccactt atttacctca
     3661 agccccttgg tagtgttgga aatcagcggg ttcggagaag ttccgagagc catgataact
     3721 gtgtctacat ctaatgtgta atcagagccc tctacctcta ccggacgtct tcttccagac
     3781 tcatccggct ctccaagctc catcttgcgg catacaatgc cctttaccca gccctgctcg
     3841 tctgccagga tctctactgg atttgtgaga aggtggaact ggattccctc ctccttcgcg
     3901 tggtgaacct cctccacacg ggccggaagc tctttctcgc ttcttctgta tacaatgtaa
     3961 acctcagcgc cgagacgaag agcagttctg gcagcgtcca tcgctacgtt tccgccgcct
     4021 actacagcta ccttgtgtcc tgctgcgatc ggtgtgtcat aatcgtcgcg gaaggccttc
     4081 atcaggttgc ttcttgtcag gtactcgtta gcggagaata cgccgttgga gttctctccc
     4141 ggaattccca tgaacttagg aagtcctgca ccggaaccga taaatacggc gtcgaagccc
     4201 tctttctcca tcagctcgtc gatggtaaca gattttccaa ttactacgtt tgtctcaatc
     4261 tctacgccca gctttcttac gttgtcaatc tcaggctgaa caacgccgct cttcggaaga
     4321 cggaactctg gaataccgta ggtaagaacg ccgcctgcct cgtgaagggc ctcgaaaatc
     4381 tttacttcat atccaagctt ggccagatcg cctgcacagg taagtcctgc agggccggaa
     4441 ccaatgacag cgactctctt gccgttcttc tcctcagctg ccttcggaac aaagccgtgc
     4501 tctcttgccc agtcagcaac aaaacgctcc agctttccga tggaaacagg ctctcccttg
     4561 attcctctga tacattttcc ctcacactgg ctctcctgcg gacaaacgcg gccgcagaca
     4621 gccggaagtg cggaagactt ggcgataatc tctgccgcct tctcaatatt tccttctttt
     4681 acctcctgaa caaaggcagg aatatcgatg gatacaggac atcccttgac gcactgtgcg
     4741 ttcttgcagt ttaagcagcg aactgcctct gccatcgcct cgtccatatc gtagcctaag
     4801 catacctcct taaagtttgt ggcacgctct ttcggatcct gctctcttac aggaactctc
     4861 ttcatcatat ctctatttgc ttccattagt cattacctcc gcagtgtccg catccgccgt
     4921 gatgggtatc tccttctctc agttttaata aagctctgcc ctcttctgtc ttgtacatct
     4981 gctggcgctt catagcctcg tcgaagttta cctcatggcc gtcaaattcc ggtccgtcta
     5041 cgcaggcaaa tttcaccttg ccgcctactg ttacacggca tgcgccgcac atacctgttc
     5101 cgtctaccat aatcgggttc aggctgacga tagtcggaag gcctaattcc tttgtgagca
     5161 ggcagacaaa tttcatcatg atcatcggtc cgatggcaac gcagacgtcg tacttcttac
     5221 cctggttctg aaccagatcc ttgattacct ctgttaccat gccctttctc tcgtaggagc
     5281 cgtcgtctgt ggtgatgtaa agatttccgg ctactgcctt catctcctcc tccagaatga
     5341 tcagatcctt tgtcttggaa ccaacgataa cgtccacgtc gattccgtgc tcgtgcatcc
     5401 attttacctg cggatatacg ggagctgcgc ccacgccgcc ggctacaaac agatactttt
     5461 tattctttaa ttcagcaacg tcttccttta cgaaatcgga agcgtttcca agaggtccta
     5521 ctacgtcgcg gaacgcgtct ccggccttta actcagccat cttctctgta gaagctccta
     5581 ctgtctggaa tacgatagtg attgttccct cttctctgtt gaaatcacag atcgtaagcg
     5641 ggattctctc cccctcctca tccatcttta caattacgaa ttcacctggt tcgcaggcac
     5701 aggcaaccct gggagctttc acatccatca ggtaaatctt gtctgccagc ttttctgctt
     5761 ttaaaatctg gtacatgtct ttttccctct cctcctgttc tttcagcgat aaatctcacc
     5821 tgtttcctat tctatcattc cttttcactt ctgacaagca aaacaagagg aaaatttacg
     5881 ttaaaaagcg tatgaattca gattcttttg tctgattttt ttattattta aacatttctt
     5941 cacttaaccc aggtacatct ccctaatttg taatacacct ttcttttttt ctatattttt
     6001 ttcgttataa aagtattttt aatcacaaaa tctgactttt tattcagtaa aattttacca
     6061 gtaatttttt ctgttttttt actattttta ttttttttcc agatttcacc gcccctctca
     6121 aggccgcaca taccggcgga actcatagca cagatcgaaa tatgtctgct cgtcgctgca
     6181 gtccgtcaca atccagccct cctgttccag gttgaccatg taggtatctg cgttgtactc
     6241 gtaatcaata aacgtaatgt gggcttcctg gcagtaaggc agaaactgtt cgtaaatcgt
     6301 ctgccctcca atgataaaga tatcctcgtc ccggtatttc gaaagctctg agagcgcctc
     6361 ctccatgctg tggactgtta cagctccctt tatcttaaag gacggatctc ttgtcagcac
     6421 aaggttggtc cggctctcca gaggacgtcc tcctggaaga gattccaggg tttttcgtcc
     6481 cattaccacc acttttccta tcgtctcctg gcggaacagc ttctgatccg ccgggatcac
     6541 ggccagcatc tgtccgttct ttccaatggc ccagtgtttg tctactgccg ctattaactg
     6601 catacttcgc tctcccttct gtcttctctg attttctccg gatactggcg tcttaaggtc
     6661 tttatcatgc tggctgcatt gatataaaac gcttcgtccg gctggtcctt tttatctact
     6721 gtggaatgaa aggtccgctc catggttctc aacgcttcct cgtcgctgtc cgtctcattt
     6781 aaaatgtcca gcatcagatc tctgcttttt ctggctgtct ccagaagaaa ttcccagatt
     6841 ccggctttat ccttttcctc taccagtcca tagtggttta aaatgatctc tcgcaccggg
     6901 atttcagcag atcggcggat ggaatcctcc acccctttat agtcaaccag gaagcttggc
     6961 atatactcct gatttctgtt catgactccc accgtctcgc tgcagagcat cacttccccg
     7021 tttatcacat aagacatgga gcatttcgtg tggccgggcg tggcaaaggc atagacctga
     7081 tctcctgaaa tctctgtcgt ctccccatct ttcagaccga tatccgcctg gatatccctg
     7141 tcgtcgtagg cgctgtccca ggaaagtccg gaggcctccg ccgcttcccc gctgaggcgg
     7201 cggatggttt ttaacgctcc cggctttacc agaatctcct ttgcccgctc tgacgcgtac
     7261 accttcacat caggccactc ctttctcact gccggcagtc ctgccacatg gtcgtaatgg
     7321 gaatgggata aaagcaccgc gtggagaggc tccccctgaa gctcctgttt gattttctct
     7381 atcatcgcgt cggcagcgta ggccatcccc gcctcaaaga gaatattggc ccttccgcgg
     7441 agcagaaata ccgcgccctc tccaactccc gtcacatcta tgattttcac agtttcagcc
     7501 ttcttatctg aaaaagccgc ctgatagatc tcctcctgct ccggcagatg ggtaacataa
     7561 cctaccggaa ttttgttttc tgtgacctca ataattcttc tggctccgtc cggtccgaag
     7621 gctccgcaca gttcaatgca gccgactccc tcctcataca gctccctggc cgcctggcag
     7681 gcctcgtcca gagtggatac gccgatcatt ctggctgaac catgatgaat ctctgcccga
     7741 tcctccgttg cacggaaatc tcccaatatt aaaaacgcaa atttcatgtc ttgcctcctg
     7801 cagttttgaa ttttctaaat ttatctgtaa gtatatcatg aaaaaacaaa agccgccatt
     7861 ggagaatcta tggcgggatt gctttttttc tctgggacgg ttataatgag tctagtttta
     7921 actgaatcta aaaagaaatg aggctgaacc gatgatcaca ttagaaagaa caagcgtaat
     7981 gaacctggaa aacgccatgc gcggggccag aaatcccatg aacagctggc accgttctga
     8041 cagctgctat gatgaaaatg gttcctatct tttaggtccc aatgatctgg atctggctaa
     8101 aagactccgc caggctggaa gcgatcaccg caaatacgtc cgccagattt tcgtgtctgt
     8161 ggatattact gctcccctct actggtggaa ggagtacgat acctacaagg tggcgacagt
     8221 ggctaactcc tgcagcacca tgcataaaat ccacagcaag gaattcacca tggacgattt
     8281 cagctgcgat cacatgacag acggggccag agcctttatg cagacgattg tagataagct
     8341 ggaggaaacc agaaagagat atctggaaac taagaacaag gaagactggt acgatctgat
     8401 tcagcttctc ccctccagct acaaccagat gagaacctgc accttcaact atgagacgct
     8461 gattaatatt tattatgccc gcaaggatca caagctggcc gagtggcata ccttctgcga
     8521 ctggatcctg actctgccct acgcaaaaga gctgattgtc ggagagggca aatagcagcc
     8581 ctttctcttc tgcaagtgaa aagacacatg aactgtcatt ggaactcacc tgacaggcca
     8641 tgtgtctttt ttattcctat tctgttttgc cattcaggga caccgaaggc cagagcttcg
     8701 gcgtcccaga tccatttaat tccagaaatc agtttttgtc tccagatcaa tatcctttgc
     8761 cttgaataca gggttctttc cctctttctt ctgcttcaga tagtcgttca tacatcttac
     8821 ggccggtccg cccagaatca ggataaccgg gaggttaatg attgccatca gtcccatgag
     8881 aacgtccgct gtgttccatg ccacgctgaa ctccatggta gcgccgaagc atacgatcag
     8941 agctgctgcc agacggaata ccattaacag agccttattt ggcgtcttgt cacagatata
     9001 tccaagtccc atttctgcat agtagaagtt accaattaag gtagtaaacg caaacagaac
     9061 cagagcgatt gtaataaaga tcgttccgaa gcttcccagc gtgttggcaa ctgccgcctg
     9121 cacgtacggc attccctgaa ggtctgtgga cggctcaatg ccggaacaca gaagcatgaa
     9181 tgctgttgca gaacagataa cgatagtatc aatataaacg gaaagcatct gaaccagtcc
     9241 ctgctttacc gggtgggata cgcctgcgga agcggctgcg ttaggagcag aacctacacc
     9301 ggcctcattg gagaaaagac ctctcttaat tccctgcata atggcagaac ctgtaaaacc
     9361 tccaaaaata gccttgaagt caaatgcctg agtaaaaata tctgcaaaca tctggggaac
     9421 gaggtttaag tgtgtcacaa taataaccag agaaaccagg atatagaaaa ttcccataac
     9481 aggaaccaga actcctgtga tcttggaaat ctgcttgctt cctccaaaga tgcagacagc
     9541 aaaggccgct gccagcacag cgccgataat gagcggcgta gtggacggat cgtagaagct
     9601 gtatgcccgg aaggaatcgg cgatattgaa agccgctacc atgttgaaac cgcccatata
     9661 ggtaacaatc aaggttcccg caaacaggat tcccagccat ctctttttca aaactgcctg
     9721 tatgtagtac gccggtcctc cgtaggagct tccgtccgct gcttttctct tgtaaatctg
     9781 tgccagggtg ctctcaataa atgcagaagc gctgcccaga atcgctacca gccacatcca
     9841 gaacatggct cctgctccac cgatgcagat agcggtggaa atacctgcaa tatttccagt
     9901 tcccactctt gacgctgtgg aaaccatcag agcctggaaa gatgagattg actctttgtc
     9961 atcgctgggt tcttttacta cgcggattgc ttctttcaga cagcggaact gaataaattt
    10021 tgtctttact gtgaaataaa taccagctcc cagaagcaga acgatcagaa tataggtata
    10081 cagccagtta ctgagggtat tgataatctc tgaaaacata tttgtctttc ctttctcaat
    10141 ttccttaatt ttcctgttgc ttgcccctta tattacagct tgaaggcgct gccaaatctt
    10201 ccccagcttc ctttcctcct ttcccctgtt tccctgtact gggttttctt tgatttagca
    10261 atttttaata atttttatat ttttttatta taatataaaa tggcgctgct gtacaactga
    10321 attttctcaa atttttccag atgcctttgc aggctgtgcc gtttttatat tcttcggctc
    10381 tttctattaa ggctcccagg caaacatatg cagattcagc tcctctgaca catatttcag
    10441 catggctttt ccgccaatgc tgtttccttt tttatccaga gaaggtccgt aaatgccgat
    10501 tcccattttt cggtccacta cagacaggat gcctcctcct acgccgctct tagagggaat
    10561 tcccacttcc actgcaaatt cgccggagcc gtcgtacatg ccgcaggtca gcataatcgt
    10621 cttaacggtc cgcacgactt cccgatccag aagtctttct cctgtctccg gatgaatgcc
    10681 gccattggcc aacaccaggc cgaacgctgc caggctcttt gccgtcacgc tgagggaaca
    10741 catcttcaca tacagttcca ggctgcgctc tatgtcgcac tcaatgatcc ccttgctctg
    10801 aagcagatag gcaatggctc tgtttctcgc gctgttggcc atctccgagg tgtaggccct
    10861 ctcatccaga cggatcttcg gatcaagaca gagctttccc gcatagtcaa gcagctcttt
    10921 gaagctgaaa ataggcatca ggtagctgac tacagtgatc gccccagaat tgatcatggg
    10981 gttgtatgga tagttgctgg tcatatccag cttcagcaaa gagttaaacg cgtctccaga
    11041 cggttccatc ctgatcttct caaatacctt gtcaaatccg cagtgctgaa gcgccacaca
    11101 gagggaaatt accttggaaa tactctgaat ggtaaaccgt ttctgagaat cccctgcctc
    11161 ataaatttct ccgtccctcg tatagataca aattcccaga tcatgcttat ctgcccggga
    11221 aagttctgga atgtaagacg cagtctcacc cttgtccact tccatgcttc ccgccagaag
    11281 agcttcctct aaaattcttc ctctctcctt atctgtcatt ttttctccct tccatctcct
    11341 tctgagagca ggccgcttct catatctcag cagtcacagc tgcactctga aaaagatttt
    11401 ttataaatta tttttatatc ttttataaat tttattttat atccatagta tagcagaaaa
    11461 tgatttgcct ttctaatacc tgatacctat aaggctatag cagattgcta caacccgcct
    11521 ggcctttttt cgcatttcat gatatacttt taacaaaatc aagcagcact ctgttttttt
    11581 ctgctgacgt tctggttcag gaggttctct atggattacg atatcaactt aaagcatctt
    11641 tcttacttta tcacaactgc ccgtctcggc tccatcaacc gggccgcaca gactttgtat
    11701 atctctcagc cccaccttgg aaaaatcatt aaggaattgg agcgcacagc cggaactatg
    11761 ctttttgaac gcaccagagg gggtgtgatc ctgactccgg atggaagaga ctttctggaa
    11821 cgggcagagg gaactctgcg ggcggcccag tcccttctgg aattccgctc tgcctccagt
    11881 ccttccgctc attccctgat ggtttccatg actcgttttt cccacattat ggaatgtttc
    11941 atcgaaattg ttctgcgcca caaaaacgac gacgcctttg tacaccggct tcgggaaggc
    12001 acagcagatg aagtgattga agatgtgtat tccggacagt ttcatgtagg agtcattcac
    12061 tttaatccgg aagaaaagaa aagcgttctc gcccgtttag cgtccatggg actgtcctac
    12121 gagacgctgt ctctggtacg gccccatatc gttctctcca ggaatcatcc gctgatccgg
    12181 gaagggaagc cagttaccct tgagaatctg gctctctatg gcttcgcccg gtatcaggac
    12241 gcagcagaag attttgccta ccatattttt tctgaaaata tcctgtacaa cttaaattcc
    12301 ggcttgaaaa tcgtttatct ggacggacgc gcctctcttc tccacctgct ggccaacagc
    12361 gatttttatg gcattggaat ttacggtttc tccgcccagg attccaccta tcaggttatc
    12421 tccattccta ttgaggaatg cagggatcgg ctggaattcg gatatattct tcccaaggga
    12481 ggtcctgtat cagaaatcac agcagaattt atagaggagc tgaaaaaccg tttttctaaa
    12541 gctttatctc cccaagcctg aaggaataga tgagcgtttc cttcaccggc ttattctcca
    12601 tctgcatcag ggcccgtctg taatagtcca gctgaagctt gtagcgttct atcagcgtct
    12661 cctcctgctc tgcgtaatcc gttttataat ctacaagaat cagctctccg ttttcctcaa
    12721 aaaaggcgtc catgattccc tgaatcagca ccagctcgtc cgaatcccag tctcctatct
    12781 cccgggccgg gattccgatg acaaactggc tctctttttt caggcggcct tctctctggg
    12841 cgtctgccat tcttctcccc agatccgact ggaaaaacgg ccagatcaca gactcccgta
    12901 ccagtgctct gtcatcggct gtcattcttc cctcttctgc aaaacgatcc agctgttctc
    12961 tgatatcctg ctttgtcctg attttatgaa actccagaag ctccatggct ctgtggtaag
    13021 cagttcccct tctggctccc tgcccctcgt ccttctcgtc tgacaaaaac ttcggaatag
    13081 taggcagaaa cgcgctctcc tccaggcttt cctcctctcc ctccttttta atgtccgaga
    13141 cggaaagctt cgtattgaga cgcagatcgt cctgccatgg ataccggcag gaggccagct
    13201 tctccagctg tgcccggtac gcttcgtctg aaagccccag agcttcctcc cagagtgtct
    13261 tctgagaagt atccatgccc agaagcatat cctttgtcag tttctgctgc acctgacggc
    13321 tgatctcctg tcctaaaagc tccttcgcca tcgtctctct gacgcggatt ctgcatcctc
    13381 cctgggctat ggccatcaaa atccagtcca gataagagct ggccagggac agaagggtaa
    13441 agggaagtcc tccctctgtc tcaaaaagag attccttcca tttttccagc tttgactcca
    13501 aattcttgtc agaagcagtc aaaattaatt tttccttggc ccgcgtcatg gctacataga
    13561 gaacccgcag ttcctccccc agattttcca gatccattct ccgcttcagc acatttttct
    13621 taagggtaga cgccttcagc ctggtctcgc tgtccagata atctgctcct attccaaact
    13681 ggggatcaat gagaattttc cctctggtat cctgtttatt aaactgcttt cccatagcag
    13741 aggcaaacac aatgggaaat tccagacctt tgcttttgtg gatactcata atccgcactg
    13801 tatttccgcc ttctgccgcc gtggacgcct ctccgaaatc tgtattatat tttttcagct
    13861 tttcaatata tttaatgaaa tgaaacacgc ctctgtagct ggtagactcg taggcagccg
    13921 ccttctccac cagcatatcc agatttgccc gccgagtctc tccagaaggc atcgcagata
    13981 cataatcata atatcccgtt cgatcgaaga ttctgtaaag cagctcgtgg atcggcagat
    14041 aaacggcctg cattctaagc tcttccatga cctctgtaaa gaaatccagc ttcctggctg
    14101 tttccccctc ctctgcttcc agacaacggt tctccttcct ataagtgtcc aggcaggcgc
    14161 agactgcccc gtacagtccc cgatcctgcc ctttctccgt attgctttta aactctgctg
    14221 tgatctctgc cagctcccga tccgtcaggc caaaaaacgg cgccctgagc actgccgcca
    14281 gaggaatatc ctgcatcgga ttatccagca ctgccagaaa attcagtatc gtctccacct
    14341 caatggtggt aaaatatcct gtcttcgatt cggcaaaggc cgggattccc atatgcccca
    14401 gcgtctccac aaagctttcc gcccagccgg aaacgcttcg cagcaaaatg acgatatccc
    14461 ggtactccgc cctccggtaa gctccttctt ctttatccca taccagacac cctttttccg
    14521 gatcggtaag ctcccgaatc ctcatgccga tcattctggc ttccagttcc tgcctggtgt
    14581 aatctgcact gtcgtcgtcc agctcctcta aaatactgtc cttcgtgtta atcaaaagaa
    14641 gctccgtgga aaaatccctc tcctcctctg aagcagactc cggaagaggc tcatatccag
    14701 ctcctggatg aagagcggcg tcctctgtgt aagccacaga gcccagcttc tctgtcataa
    14761 ttttaaagaa cacatcgttt gtgctttcca gcacctgagg acggcttctg aaattctgat
    14821 gtagctctat cttttgaaac tggctgtcct ccctggtgta ggactgatat ttttccagaa
    14881 acagttccgg tctggccaga cggaatttgt aaatactctg cttcacatct cctaccataa
    14941 atacgtccgg ctctccaaac cgctctctgg aaactgccct gatcagggcc tcctgcacca
    15001 gattgctgtc ctgatactcg tccaccagga tctcgtcaaa ctggcgggcc agatcgtccg
    15061 ccgtctcgct cagttctccg ctgtccctgt aaagaacctg cagcgccagg tgttccagat
    15121 cgttaaaatc caccagattt ctctctcgtt ttttagccga aaaacgctgt tcaaattcct
    15181 cggccagtga aagaagcata agaattgaat ctctgcttcc cgccaaatcc gaaagtatct
    15241 cctcctctga ggcaaagaga aactgagctt tgattttttc taacgccttc ttgatccgct
    15301 tgcggcactc tgccacagcc tccttctttt ccggagagac agcggaattt ttgccccgga
    15361 tagccgccag cttgggaaat tcaaagctgt ctgcctcccg ggcaagcata ccatagcccg
    15421 atacctgttc catccgctct gcatgagcca gatcagataa aatcatagga agatacggtt
    15481 ccgggccatc cggctccctg cacagcccgg acgccgcttt cagctccttt acccactctg
    15541 aagcctgagt ttttacgtcc gccagaagaa accgcatcca ttctgtctga tccagggctt
    15601 ctaaggaagt atccgacagc tcctttctgc actgcgctat ccactctccc ggccacggat
    15661 tgctctgaga gaaactgtaa acctgataaa tatattcgtc aattccgccg tccgcctttc
    15721 cagaggcaaa ggcgtctaca aattcttcaa atttcggatc cttcttccca taccagtcct
    15781 ccagaagttc ctccatcacg tctcccctca gaagcagcat ctcgccttcg tctcccactc
    15841 gaaatgccgg atctaaatcc aggcagtcga aatgctctcc cagcagatgc aggcagaagc
    15901 tgtcgatggt ggtgatctgg gcatactgaa ccagaaccgc ctgctgctgc agatattcat
    15961 tatccggctc tttcgccagc ttcttttcaa tggcgtcaag aatcctctct ctcatctcgg
    16021 aggcagcggc tttcgtaaat gtcatcacaa gaagtctctc tatatctccc ggatgctcct
    16081 tgtctgtaat catctcaata atacgctcca caagaacggc cgtcttcccg cttcccgctg
    16141 cggcggatac taacaaattc ctgtgcctgc tttcaatgac ctgtctctga tcccgggtcc
    16201 aatttactcc cattctgctg cttcgcctcc ttctgtctca agagtctcct gctcatcttc
    16261 ctcaacgctt ttctcaattt cttcccagac cgcctctggt ttcatggact taaaccgcct
    16321 gaatccatat ccctttgtct tcagatcaaa tccgcagatc ccatggtagg gacagtaatc
    16381 gcaggctgtt ttctctcctt ttttataagg atctaccgta attcttccat ccagaatttc
    16441 tcttcccata gccttgattt tctggttgac aaagccggtc atcgccaaaa aacgcttctc
    16501 atttgccaca gaggattttg cctcctggat gattcccgcc ttataagcga caggaatgac
    16561 gtccgactct gtctcaatcc tccgatccag atgtgagata gcctccgccc ggctgttaac
    16621 cagaccgttc atgcgaagag tccttaaaat ctctgcttcc ttttcctcct cgctcatgtc
    16681 ctccgtcttt tccaccatgg gatccgcaat attgtagtaa aaaattcctg ccggaagcac
    16741 ctgcttgtcc gggtgtctgc gctgttcctt ctccatggca gcatccagat agacgaccag
    16801 ctgcatctga agcccgtaaa acagctctgt cagctcaaac ttcgtcttcc cggttttata
    16861 atcgataatc ttcacataca gcttatcccc gtcctcgcac agatccatcc tgtcaatgcg
    16921 tccctgaaga tgaacggcct ccgtcctgga aaccggaatc ttcatcgcct tcagattgtc
    16981 tgccggagta aaagtaagtt caaagccagc cggctcaaaa tctcccttct tcagctgttc
    17041 tgtcaatgcc cagactgtcc tgtctgtaat ctgctccacc cggcgcccca gatactcgtt
    17101 cctcgccgta tcggaaacta ctgtattccc gtactctctc gtcacttcag atacgcatcg
    17161 gctgaccagt tcctttctct ccctgtcatc cagctggcgg aagctccttc cctcctcctg
    17221 catggtctta aaaaacaggt caatggagct gtggaagaga tttcccagat ccgcagcagc
    17281 cagctcatac tctctgcgct cccgaagctc cagcccaaaa cttaagaaat gagcgtaggc
    17341 acaggcagca tagcgctcca tcctggtcac gctgccacgg agaatggggc tgtagagctt
    17401 ctgggccgct gtccttccaa ttcccttatc ctcatatacg tggaatgcgg cttctaccag
    17461 acgtttcgtc tcttccctct tatcttcatc cgtataaaaa tggcggtaca gctccagaaa
    17521 ctccggtctt gacaccgcat gttccaaatc cctcaggcca gcgatcagag ttcttctgcc
    17581 ggctggagct gacagcgccg cctccctgta ctgatccatg cgcgtctctc tcagctcagg
    17641 aaacagcttc ttcacctgtc cgatcaggct ggacggccgg agactctttc ctgccgacga
    17701 ggtctggctc caggtcagat agagaaaatc tgaagctttc gtcatcacaa gatacaggta
    17761 cagacgctcc aaaaagcctt cttccctggc tgtaggagcc agctccaccc ctctttcctt
    17821 cagaatcctc cgttctgcct ctgtcagaat gcctccgcgc ctggcggctc ccggcacaat
    17881 tccatcgttc accccaatga aaaacagagc cttgacgtgg gacagacgcg ttctggtcaa
    17941 atctcctgtc actacccgat ctacgacagc cgggatcaac cccacctgaa tctctgcaaa
    18001 acccgcgtcc agaatctggg catactctct ccggctgact gtctcgtccc ccaaaagcgc
    18061 agccaggcgg tcaaacaaat ccatcacaag cccataaacc tggctgtatt ccttctcaag
    18121 ctcagcctct cccatctcgt gaaacgcttt ttcccagcgg gacagacgct tttccgcctc
    18181 cacgctctcc agaaactccg ccaaagccgc cgtcatctct ctgactgtag actggcggtc
    18241 tgaaaatacc tccttcaaag gaagaaacgg atgcagaaga gaatctttaa actcgttcaa
    18301 ttcctccaga tttaatcttt ctccatcctt ataggtgcgg tcccaggacg cgctccagcg
    18361 cttaaatcca cggattccca tggctttcac ataattttcc agcctggaaa gcttctcctt
    18421 ctcctctgtc accatgccgg tcttcaaata gcggaacatg ctttcatagg aaaagttttc
    18481 cgtaatcgtc tccagcgcgg cccgcagaag ctctaccaca ggattgctca gaatattttt
    18541 cttgctgtcc aggaagaagg ggattccatt ctcctgaaac tgcctggcaa gctctccgga
    18601 ataatccggt aaagctcctg tcactacggc gatatcgcgg taacggtatc ccttctcctt
    18661 caccaggtgc tgaatctctg tgcagacaaa ctgaatttcc ccaatgggat tttccgcctc
    18721 atggagaagc agactgtccc cctgcgcccc ttcaaaacgg cctgcccaag gccggaacag
    18781 gcccctctca atcgcagaaa gagccggact attctgaaag cggcggcatg gtcctgtcag
    18841 gagaatatcc tcatccctcc ccgctcctgt acctgacgcc aaatctgtca gcctgcagac
    18901 agtatgactg ctcatgtgga acagattctg aatcggtttt tcacggtagg ggttctcctc
    18961 aggaggcatc gtcactgtca caaccacctg gcggcagcag gttaaaagaa gctctaaaag
    19021 ccggtactgt acaggagtaa atcccgtata tccgtcgaga gtcaccacgc ttcccctgat
    19081 taaccgggac ttggggagca cgcggcagag aatgtctaaa atctcctcct gggcaataaa
    19141 ccgctccctg gtgtactccc ggaagccttc gtacagctcg ctcatatcag acagcttctg
    19201 ccgcagcatg gcgctgtccg cgctgtctgc catctcccgt atggtctccc ctgaaattcc
    19261 gtactgaaac agctctgaca gcatggactt cagttccccg ataaaaccgg actgttccag
    19321 atggctgcca aacagacgca gattcttttt cctggctgca gctaccttcc gaagcaccag
    19381 agattttccc atatcatcca gtaccgctgg cgtctccaca gccaattcct caaaaatacg
    19441 gtaagccaga cgttcaaaac tgacgatatc aatattcctg acgccatggc gcgggtgcat
    19501 cgtcacaata tccttctgag tctgcatggt aaactgctcc ggcacaatgg caaaaaattt
    19561 tccttccgga ttctccatgg aacatttaat taaattttca tagagtacat gggttttccc
    19621 ggaaccggaa ccgccgatga taaactgtaa tgacatggaa acctccttgt atttatgtga
    19681 tatctccatt gtataacaaa catatgttct ggtcaagcag aaaatatatt ttgccttgga
    19741 cgctgtgaat aaatcatatt ttttcccata cactgtacta aataatacca agaggtcttt
    19801 ttatgagctc taaaacgaaa atcgtggtgc tccggatgaa ggaaatcatc tataccgcca
    19861 tctttatcgg gctgggaatc atccttgtaa cgctgctttt tatcatgttc cgtcccaaaa
    19921 aggaacctca gaccgtctcc tccggccagg ttcaggccgc tcaggcctcc tacacccccg
    19981 gactttaccg ggcttctctg tctttaggaa gtcagaatgc agatttggaa gtggccgtgg
    20041 acgcagatca cattaactct gtttccatga cgccgctgag cgattcagtc gaaaccatgt
    20101 acccgctgat ggccccggct ctggaacagc tgtccgagca gatctgctcc tctcagtctc
    20161 tggaaaacct tacatatcca gagggaagcc agtatacatg ctctgccctg gtccaggcca
    20221 tcgaatcctg ccttttaaag gcctccagcc agtagaaagg caagagaaaa ggatgcgaag
    20281 catctggttc tgacaggctt acgcatcctt ttcatctgaa atatcttata ctgtttcgga
    20341 ctttttctct cctccgtctc cctccgccgg gacagccggc tttcgattca ggttaaacgg
    20401 cagattcaga ctcataatgt ttaaaaccac acccttggcc tcaggagcga ctaaaacggc
    20461 aagcttatct gcatctgccg ccacaggacg gaacttattt tctctgttaa acttctggaa
    20521 ttccagcgca tccgtaaaaa tcggctggta catctggcca tcctttaact tggctaacgg
    20581 aactcccttt tcttccttct gaagggctaa aatatatttt cccctcttaa aatcagccag
    20641 cagctcctcc agcagttcgc tggttttctc atccggctgc ggattcggct gctttctcat
    20701 ctcctgggca tagtaaagag cagttaaatg aagctgcgga ttctcaatcc ataccgttcc
    20761 ctccggctgc tcttccggtt tcttccgtct gaccagctcc tctaactgaa acctcgtatt
    20821 ttcactgccg tttctcatca caatggcgtt aattcccatg gtaaacaggc tggtaaagaa
    20881 aagaagcttc tgcttttcct caactctgac aatcgacacg gggattttct cctccagcag
    20941 agcctttccc ttttctctgg cttcatcctc tgtaaaaaac atgaaaatct cgtcgtcaaa
    21001 ggtctctgcg tcgcactcta catacggctc ctttgtacag gctgacatta acacaaataa
    21061 ctccggaacg cttctcatct tctgaagaag cgccgtcttc tccagcactt cgctgcttgt
    21121 ttcactattc ataagtatat tctccctccg ccttctttcc cctctgccga aaagcggctt
    21181 attttctgat attcattata agcaaaagag ttttttgtgt caactgaaag agacggcgga
    21241 ccgtacgcaa agtttctcaa aaagaacaat ctttttccct tttctatctg gacattgtat
    21301 acaggaaatg tataataata gcggcaggtg tgaatatatc ctgcctatta ctatgtttac
    21361 aagggggaac ttatggaaaa gatgcgtccc atgctgttta caacatggaa aacctacagc
    21421 aaagaacagt tttttaaaga tctgatagct ggaattgtgg tggcgatcat tgcccttccg
    21481 ctgtctatcg ctctggcgct ggcctccgga gtaggtccgg agcagggtat ctacacagct
    21541 attgtagcgg gcttcgttat ctcgcttctt ggcggaagcc aggtacagat tgcaggtcct
    21601 actgccgcct tcgcaaccat tgtggcggga atcgtagccc gaagcggtat ggacgggctg
    21661 gccgtggcga cgattctggc aggaatcatt ttgattctta tgggattctg ccggttcgga
    21721 tctctgatta aattcattcc gtttaccatt actactggct ttacctccgg tatcgccgtc
    21781 accattgtca tcggacagct gaaggacttc ttcggggttg tctatccgga aggaatgccc
    21841 actatcgaaa ccatggaaaa gctcaaagcc tttgctgcag gatttgtaac gctgaacatg
    21901 gacgctgtga ttgtggggct tgtatgcctg gcgattctca ttgtcacgcc gtatttctct
    21961 gagaaaattc caggctccct gctggcggtc atcggcggaa tcctgatggt gaaattcctt
    22021 ccgctgaacg tcaatacgat cggcgatctc tacactatca gcagcgcgct tccatccttt
    22081 catctgccgc agctgagctt tgacatggtt cagtctgccc tgccggacgc tttcactatc
    22141 gccgtgctgg ctgctattga atctctcctg tcctgcgtgg tggctgacgg catgatcaac
    22201 ggaaagcacc gttctgacat ggaactggcc gcccaggggg ctggaaatat tgcctccgcc
    22261 cttttcggtg gaatccccgc tacgggagcc attgccagaa cggctgcaaa catcaaaaac
    22321 ggcggccgca cgccggtagc aggtatggtt catgcgcttg tgctggtgct gattctcgta
    22381 gtcttcatgc cctacgcagg catgatcccc atgccggcca ttgcggcgat tctattcatg
    22441 gtcgcctaca acatgtgtca gtggagaacc tttgcagagc tggtaaaaac agctcccaaa
    22501 agcgatattg ccgttttgat catcaccttc ttcctgacca tcgtctttga cctggtcgtt
    22561 gccatcgaat tcggtattct gcttgcaggt cttctcttta tgaagcgcat gagcgacgtg
    22621 acggaggttc acagctggaa atacgcggag gatgaggagg aagcggagcg tgaaaagctg
    22681 agacaactcc ctccccatat caatgtctat gagatcagcg gcccgctgtt tttcggagct
    22741 gccgacgaaa tcggccggat tgtggccagg gagcgcgcta cctgcctgat tcttcgtatg
    22801 agaagtgtcc cgtctatgga cagcaccgcc atgaacgcta tgaacgacct gctgaagcgg
    22861 tgccagaaaa aaggaattac cctgattctc tcccatgtca atccacagcc tatgaaggtc
    22921 atggagaagg ccggatacgt ggacaaagta ggacgtgaaa atttctgtga aaacattgac
    22981 gcggcgattg caaaagccga ggagctggta aaataaaaac agctttataa aaaaggaggc
    23041 ctctgcctgt caggcgggaa gtctcctttt ttgcttctgt ctaatcattt ttctgttttt
    23101 tgtacacact gctaatgagc ctgaacacct gctccgccgt ttccttcata tttcttctgg
    23161 cacgctcctt ctccatcgcc tcctctctgc ttattggtcc tctcacaatg ggaaaatagg
    23221 cgtcaatgcc ctgttccagg cagagtctgg cctccggcgc caccgcaccg gcaaaagcaa
    23281 tcacctgaca gccgtattct gccgccagct tcgccacgcc cacaggcgcc tttcccatag
    23341 ctgtctggcc gtctaaacgc ccctccccgg taatcactat atctgcattc tggagttctt
    23401 cctccagccc cactgcttcc atgataatag aaattccagg ctccagcgac ccatttaaaa
    23461 aggttctgaa ggcgtagcca agtcctcccg ccgccccgct tcccggcaaa tctgccgtat
    23521 cctttccaag gtctctttta acaagatttg aaaaatgaag aagcgcccgg tccagctcct
    23581 ccgccatctc ctctgtcgct cccttctggg ggccgaatac catgctggct cccgtctctc
    23641 cgcacaaagg attgttcaca tcacaggcga tctggaaggt acactcggaa agtctgggat
    23701 ctgctttgga actgtcaatc cgatcaattt ctgccacatc tcttccaaaa cagccagtct
    23761 ccttcccctc cctgtccaga aatgaaaagc ccagggctgt cagcatcccg atgccgccgt
    23821 cattggttcc gcttcctccg attcccacaa caaattttct cagccccctg tccaaggcat
    23881 cccggatcag ctccccggct ccccggcttg tagtataaag cggattccga agctctgatg
    23941 ggatataggt cagaccaacg gccgaggcag tttctatgac agctgtattt gtttctctga
    24001 gcactgcgta agaacttttg accggttttc caagaggccc tgttactgtc agctgaattt
    24061 cctctgcacc cattccctcc acaaaagcgg ctgccgttcc ctcacctccg tccgctaacg
    24121 gctttatcac gatttgtgcg tccattccag atgcttgtat cccctctctc actgctgccg
    24181 cggcctctgt cgaggacagg cttcccttaa aagaatccat tgctattacg attttcatag
    24241 tatttaatct ctccacttct gaggcttatt atctttattg tgatattatt atacaaacta
    24301 aaaatctgtt tgactatatt atagaaaaca tattatactg ttatttaata ttacagaaaa
    24361 catttttatc gaaggagaat ttcatgaagc tttcccagca caatgcctgt cagatcgtca
    24421 caaatatcaa tgaaattatc aatcaaaaaa tgaatctgat caatgccaac ggtattatta
    24481 ttgccagcac agatgaatcc agaataggaa cttatcatgc cggcgctaag aaagtaaacg
    24541 cttaattttt aggtatgata gaaaaaatcc ccgactactt ttcagtagcc ggagcacctt
    24601 gacaattc
//
LOCUS       DBMDUW010000037        23586 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1426_length_23586_cov_3.176794, whole genome shotgun sequence.
ACCESSION   DBMDUW010000037 DBMDUW010000000
VERSION     DBMDUW010000037.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 23586)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 23586)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23586
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1426_length_23586_cov_3.176794"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(141..1415)
                     /gene="purD"
                     /locus_tag="ACZPCR_08035"
     CDS             complement(141..1415)
                     /gene="purD"
                     /locus_tag="ACZPCR_08035"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HIR1230860.1"
                     /translation="MKILIVGSGGREHAIAWKIAQSPKAEKIYCAPGNAGIAGIAECV
                     PIGAMEFEKLADFAVEHQIDLTVVGMDDPLVGGIVDVFEERGLRIFGPRKNAAILEGS
                     KAFSKDLMKKYGIPTAAYENFDDPEKALEYIKTAPMPIVLKADGLALGKGVLICNTRE
                     EAEEGVRSIMLDKKFGSAGNQMVVEEFMTGREVSVLSFVDGHTIKIMTSAQDHKRAQD
                     GDQGLNTGGMGTFSPSPFYTEEVDRFCREHIYQATVDAMKQEGREFKGIIFFGLMLTE
                     NGPKVLEYNARFGDPETQVVLPRMKNDIVEVFEACVDGTLDQIDLEFEDNAAVCVVLA
                     SDGYPVKYEKGLPIRGLENFQDKDGYYVFHAGTAFDKDGRIVTNGGRVLGVTATGSDL
                     KEARANAYKATEWIDFDNKYMRHDIGKAIDEA"
     gene            complement(1450..2055)
                     /gene="purN"
                     /locus_tag="ACZPCR_08040"
     CDS             complement(1450..2055)
                     /gene="purN"
                     /locus_tag="ACZPCR_08040"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006855640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HIR1230861.1"
                     /translation="MLRVGVMVSGGGTNLQAILDSIDNGTIRNARVEAVISNNRSAYA
                     LERARNHGIEAVCISPRDYESREQFNEALLEKVNEYQLDLIVLAGFLVAIPAAMIQRY
                     RNRIINIHPSLIPSFCGVGYYGLKVHEAALKRGVKVTGATVHFVDEGTDTGPILLQKP
                     VEVKEGDTPEILQRRVMEEAEWILLPKAIDMIANGEIEIGR"
     gene            complement(2049..3080)
                     /gene="purM"
                     /locus_tag="ACZPCR_08045"
     CDS             complement(2049..3080)
                     /gene="purM"
                     /locus_tag="ACZPCR_08045"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009203055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HIR1230862.1"
                     /translation="MDYKNAGVDIEAGYKSVELMKKYVQGTMRPEVMGGLGGFSGAFS
                     AATFKDMEDPVLLSGTDGCGTKVKLAIIMDKHDTIGIDAVAMCVNDIACAGGEPLFFL
                     DYIACGKNYPEKIAEIVKGVAEGCLQSEAALIGGETAEHPGLMPEEDYDLAGFAVGVC
                     DRKDMITGEHLKAGDVLIGMASTGVHSNGFSLVRKVFEKELTREGLNTYYDELGKTLG
                     EALLMPTRIYVKALKSLKKAGVTVKACSHITGGGFQENVPRMLKEGTHAVIRKDSYEV
                     PAIFKMLAKKGDIAEDMMYNTYNMGIGMIVAVDPADAEKAMEAIKAAGDTPYVIGSIE
                     DGEKGVTLC"
     gene            complement(3138..3653)
                     /gene="purE"
                     /locus_tag="ACZPCR_08050"
     CDS             complement(3138..3653)
                     /gene="purE"
                     /locus_tag="ACZPCR_08050"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002575282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HIR1230863.1"
                     /translation="MAKVGIVMGSDSDMPVMAQAADFLEKMGIEFEMTVISAHREPDV
                     FFEYAKSAEARGYKVIIAGAGKAAHLPGMCAALFPMPVIGVPMKTSDLGGVDSLYSIV
                     QMPSGIPVATVAINGGKNAGILAAKILAASDAELLEKLKKYSEEMKNEVVEKAEKLDK
                     IGYKEYVAQMK"
     gene            complement(3809..5911)
                     /locus_tag="ACZPCR_08055"
     CDS             complement(3809..5911)
                     /locus_tag="ACZPCR_08055"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HIR1230864.1"
                     /translation="MRYEKGVCYTEKFREENEAVRERHELAAARIREIPLENTTGERF
                     VRYFKRTAEFILLCEEVFQRQASGELLEAELSELRSLNRRLYEDILPGNYEESFANPA
                     YACRELTEKYGAYLSFLYTEIRGMIVYAYESRLTDMTILEEVFIEVYNLFEGEEPEEK
                     ELKSVLYWFVSDYCDVTLSYRIRESLDPSLDFAGTIIKNSDLGDERYLYQFGEYISDT
                     ERSISAFLNELPEETVRKMADTFTEGYRKGFEAMGRDLSKKQTVQLRFPLGFERMMRY
                     AAENFEAMGLSPIFLRAAVGTMNRTASRTNGYFGFSPNRQYEYDHRYDNALYMDKAFK
                     ERKLSVLRVAYEEYKALAAVYGGPAVLETFGEEGFQPENKKEAFTLSEKQEKLVHAYA
                     NESMQILDGYIPGDETSFTIISFPIPQIGDQFQEIFEETIRINTLDYELYKRVQQTII
                     DVLDQASYARVTGRGGNKTDLKISLMELKDPAKQTRFENCVADVNIPVGEVFTSPVLQ
                     GTEGTLFVGNVYIGDFQFKNLCIRFENGKTVDYTCENFADEEECRKLVKQVILKNHDS
                     LPMGEFAVGTNTTAYAVGVKYGISDRFPILIAEKTGPHFAVGDTCYSWSEDTPVYNPD
                     GKEAVARDNEISILRKEDLSKAYFGCHTDITIPYSELDTVEAVNADGSAVCIIKDGRF
                     VLPGTEELNVPLETVEGC"
     gene            complement(5916..6239)
                     /locus_tag="ACZPCR_08060"
     CDS             complement(5916..6239)
                     /locus_tag="ACZPCR_08060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6142 family protein"
                     /protein_id="HIR1230865.1"
                     /translation="MAQKTKKISYIKKPMARNGFICLGLAAVALFLCLTGLGISIRNQ
                     GNTPVGGTAVCFSSFLFAVFGVIYGWASFQEEEKNYILAKIGAPISGLIVIFWIVLIL
                     IGLKG"
     gene            complement(6205..6687)
                     /locus_tag="ACZPCR_08065"
     CDS             complement(6205..6687)
                     /locus_tag="ACZPCR_08065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002600275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HIR1230866.1"
                     /translation="MWKREKTHQKICWILFFSYLLMLTYFMFFSDGFGRSEYTEYHYN
                     LTLFKEIRRFYTYRELVGTKAFLLNIVGNVVCFMPFGFILPIITRLGERWLNTLLLSF
                     LLTLSIETIQLVFRVGSFDVDDMFLNTVGGAAGYVSVTMLKWIRRAFHGSKNEKDFIH
                     "
     gene            complement(6829..6978)
                     /locus_tag="ACZPCR_08070"
     CDS             complement(6829..6978)
                     /locus_tag="ACZPCR_08070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230867.1"
                     /translation="MERVYKTMRNAGACSIVIGSVMIVTGLAAGVMAIVSGAALLRRK
                     SEITF"
     gene            complement(7012..7692)
                     /gene="pyrE"
                     /locus_tag="ACZPCR_08075"
     CDS             complement(7012..7692)
                     /gene="pyrE"
                     /locus_tag="ACZPCR_08075"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005425209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HIR1230868.1"
                     /translation="MESYKQEFIDFMVESQVLKFGEFTLKSGRKSPFFMNAGGYVTGS
                     QLKKLGEYYARAIHSVYGDDFDVLFGPAYKGIPLSVVTAIAYSELYGKEIRYCSDRKE
                     EKDHGADKGSFLGSKLQDGDRVVMIEDVTTSGKSMEETVPKVKGAADVKIVGLMVSLD
                     RMEVGKGGVKCALEEVKDLYGFPTNAIVSMKDVVEHLYNRECQGKVVIDDQIKAAIDA
                     YYEQYGAK"
     gene            complement(7760..8662)
                     /locus_tag="ACZPCR_08080"
     CDS             complement(7760..8662)
                     /locus_tag="ACZPCR_08080"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007859818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HIR1230869.1"
                     /translation="MNMKVNLAGVKLKNPVMTASGTFGSGAEYGEMVDLNRLGAVVTK
                     GVANVPWPGNPTPRIAETYGGMINAVGLQNPGFDVFAKRDIPYLKQFDTKIIVNVCGK
                     TTEDYIDVVEKLSDQPVDMLEINISCPNVKEGGIAFGQDPKAVEAITREVKRHARQPV
                     IMKLSPNVTDITVMAKAAEAGGADVLSLINTITGMKIDIHKRAFAVANKTGGLSGPAI
                     KPVAVRMVYQVANAVKLPIIGMGGIMCADDAIEFMMAGATAVSVGTANFHNPYATQEI
                     VEGMEAYMKKYQVEDINSLIGIVK"
     gene            complement(8662..9426)
                     /locus_tag="ACZPCR_08085"
     CDS             complement(8662..9426)
                     /locus_tag="ACZPCR_08085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HIR1230870.1"
                     /translation="MAQIKETAVVYSQEMLAPDIYSMWIATKAAADAKPGQFISVYTK
                     DGSRLLPRPISICEIDKEEGRLRIVYRIAGAGTEEFSHYQSGDSIEIMGPLGNGFPQE
                     GEKVFLIGGGIGIPPMLELAKQLNCEKQMVLGYRDANLFLKKEFEAYGQVYVATEDGS
                     AGTRGNVLDAIREHGLTADVMYACGPTPMLRALKEYAAQNHIRCYISLEEKMACGIGA
                     CLACVCKSKDVDHHTNVHNKRICKDGPVFLAEEVEL"
     gene            complement(9484..10401)
                     /gene="pyrF"
                     /locus_tag="ACZPCR_08090"
     CDS             complement(9484..10401)
                     /gene="pyrF"
                     /locus_tag="ACZPCR_08090"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HIR1230871.1"
                     /translation="MVSKLIEKIQKTKAPICVGLDPMLSYIPEHVTKKAFAEFGETLE
                     GAAEAIWQFNKEIVDATCDLIPSVKPQIAMYEQFGLPGLAAYDKTVKYCQEKGLIVIG
                     DVKRGDIGSTSAAYATGHLGTVQVGSQTLSGFNTEYITVNPYLGTDGVKPFVDVCNQC
                     DRGIFVLVKTSNPSSGEFQDRLIDGRPLYELVAEKVVEWGDASMDGAYSNVGAVVGAT
                     YPEMSKVLRKLMPRTYFLVPGYGAQGGTAEDLKYCFNEDGLGAVVNSSRGIIAAYKKD
                     AYAKFGPKHFGEASRQAVIDMIADINSVL"
     gene            complement(10500..11285)
                     /locus_tag="ACZPCR_08095"
     CDS             complement(10500..11285)
                     /locus_tag="ACZPCR_08095"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009295958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HIR1230872.1"
                     /translation="MNLYEAIGVRHSVRKYSDKEVTEKLREQILAFARTASPLNDRIQ
                     VDFEIIDNRDKKAPMKGVWKVEAPWYFVLYSEPEEGYGRNGGYLMEQIVLYMTVKGLG
                     TCYLGGSTVKRKRSDGKRQVMVVAFGYPEGKLFRESSLAKRLPLNELCVFKEEAGETM
                     KTVLKAARLAPSAFNSQPWRFIVYTDRIYVFAKKDSGVLQGFRSLVPAAGLMRDFSVG
                     VMLSHIMLAAEELWLELETATEEQFAAKSYKNGVYVATLAIRQ"
     gene            complement(11335..12027)
                     /locus_tag="ACZPCR_08100"
     CDS             complement(11335..12027)
                     /locus_tag="ACZPCR_08100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HIR1230873.1"
                     /translation="MESIAGTSLYFGMLLSVGAYLFGVWLKKKTGLSILNPLLVAIIA
                     VILFLKVFHVSYEAYNKGGEYLSYFLTPATVCLAIPLYKQLELLLNNKLAVGASILTG
                     VLGSAGSVLVMAKAFGLNHQIYVTLLPKSITTAIGMGVSEEAGGIVTLTVVSIIVTGI
                     IGNIIADLVFQLLKIEEPMAKGLALGTSAHAIGTARALELGEVEGAMSSLAIAVAGVL
                     TVIVVPLISGMI"
     gene            complement(12029..12394)
                     /locus_tag="ACZPCR_08105"
     CDS             complement(12029..12394)
                     /locus_tag="ACZPCR_08105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006780910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HIR1230874.1"
                     /translation="MKFIKGITIIFGITMIGEFLNVLLPLPIPSGVYGLFLLLGALCL
                     KAVKLEDVEEPGGFFLDTMPLMFIPAGVGLMNSWDVMESVLIPLTVITAASTIFVMAV
                     TGKTAQHIIRKNRQEGQEE"
     gene            12540..13367
                     /locus_tag="ACZPCR_08110"
     CDS             12540..13367
                     /locus_tag="ACZPCR_08110"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012792.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1230875.1"
                     /translation="MDIIRTSLLSAGQADEIKELLNGCRDSKGQTPFFPFEDGDLFYL
                     LFTETDDNAASRILACAAALSFFEESGAPYAECSAFTRPVLRQKGYFSLLFDELSQDI
                     EEVDLYFPVTDPEPGTLAALASLEAVRDRDEYRMELELELECAKAFSGAPFQETSAPG
                     TWKVPGSRLHTQWEETEHDSFLLSFYQEEKAVGNCCLSFFGDSACFYSFEIKEELRGL
                     GLGWEALSLTLSLLLKGLPRPGCRRLSLHVSGLNTPAISLYRKAGFHIKESLSYYLY"
     gene            complement(13890..14633)
                     /locus_tag="ACZPCR_08115"
     CDS             complement(13890..14633)
                     /locus_tag="ACZPCR_08115"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008728 - GTP diphosphokinase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HIR1230876.1"
                     /translation="MSFNQNPNSELNQSVVIGPREVEVPESLIGEAIEFRNEMMKYSC
                     AIRELKTKLEVLNDELSVRNQRNPIEMIRSRVKKPQSIFEKLKRRGLPVTVESMRENL
                     DDIAGVRVICSFIDDIYDVSRMLARQDDIRVIAIKDYIRSPKVNGYRSYHMILEIPVF
                     FSNCKQYIRAEVQIRTIAMDFWASLDHQLKYKKEMTEEEAAEIGEDLRRCAEVIAGTD
                     WKMLEIRRKIEDREQMKEYDINKGREKVV"
     gene            14864..15709
                     /locus_tag="ACZPCR_08120"
     CDS             14864..15709
                     /locus_tag="ACZPCR_08120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002575834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-amino acid aminotransferase"
                     /protein_id="HIR1230877.1"
                     /translation="MKNLGYYNGTFGPLEEMTIPMNDRAGYFGDGVYEATLARNGKIF
                     ALEDHLNRFYNSAGLIRIPVPYTRQELTDILYSMLEKMDDSEVLVYWQLTRGTAIRNH
                     IFPDASVKPNLWITMKPGKNSNPDRALKLTATEDTRFLHCNIKTLNLLPNVMAAQKAE
                     EAGCDECIFHRGDIVTECAHSNVSILKDGVFITHPTDHYILPGISRMHLIQECKRLGI
                     PVDETPFTMKELYEADEIIVSSSTKLIVRACELEGKPVGGKAPELFKKLQDAYLERFQ
                     KETEQ"
     gene            complement(15845..16669)
                     /locus_tag="ACZPCR_08125"
     CDS             complement(15845..16669)
                     /locus_tag="ACZPCR_08125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-loop NTPase"
                     /protein_id="HIR1230878.1"
                     /translation="MSECNHDCGSCSADCASRQPASFLEPLNPQSTVKKVIGVVSGKG
                     GVGKSLVTSLMACKMRARNHRVGILDADITGPSIPKAFGVHETVGVTEDELMIPCESQ
                     TGIQMLSSNLILEHETDPVIWRGPIVGGVIKQFWGQALWKDIDYMFVDMPPGTGDVPL
                     TVFQSLPLDGIIIVTSPQDLVSMIVAKAVNMAKKMNVPIIGLVENMSYLLCPDCGRKI
                     SVFGESKADEVAKEYGIPMLAKLPIDPKIADSVDQGVVEYVESPWLDEAADIIEKM"
     gene            complement(16896..17468)
                     /locus_tag="ACZPCR_08130"
     CDS             complement(16896..17468)
                     /locus_tag="ACZPCR_08130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HIR1230879.1"
                     /translation="MKKLAEVYAQSWKEVRHVRSLTTAAMFMAVSVVLGYFTIEAGPY
                     LKIGFGSVANEFVYYLFGPVLGVVYGCLLDLVKFVAKPTGAFFPGFTMVTMLAALIYG
                     TFFYRRTLTFSRVLAVTLCVDLICNVFLNTWCLSILYGKGISVLIGPRFVKNMVMWPV
                     DSFLFYIIAKKLEDFGLVRAIRRFGSPGKA"
     regulatory      complement(17564..17674)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01831"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="THF riboswitches regulate genes encoding folate
                     transporters and folate metabolism; They are most commonly
                     found in Clostridiales and Lactobacillales; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="tetrahydrofolate"
                     /db_xref="RFAM:RF01831"
     gene            complement(17665..18219)
                     /locus_tag="ACZPCR_08135"
     CDS             complement(17665..18219)
                     /locus_tag="ACZPCR_08135"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HIR1230880.1"
                     /translation="MLDMEFRILYWLQELRSPVLDQAMEAITHLGDKGWFFILLGAAL
                     FFIPRTRRAGTAVLLSLLCGMIVGNLCLKNLVMRPRPCWIDASVPLLIPVPHDYSFPS
                     GHTLAAFETAVSIFLVNRKWGTAFLIFAALIGLSRMYLFVHFPTDVLSGAALGIFIAW
                     FVKKGIEKYRLCDILRVQKNKKAE"
     gene            complement(18212..18652)
                     /locus_tag="ACZPCR_08140"
     CDS             complement(18212..18652)
                     /locus_tag="ACZPCR_08140"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HIR1230881.1"
                     /translation="MKYEVYEHKTQYYETDQMGIIHHSNYIRWFEEARVHMMEQLGMG
                     YDAMEEAGVISPVISIHCEYKSMTRFGETVRIITNLKEYNGIKMTIEYTVLDCRTGQV
                     RCVGESRHCFLTRDGKPVSLKRNYIEMDKAFREFKKENEENENA"
     gene            complement(18757..19023)
                     /locus_tag="ACZPCR_08145"
     CDS             complement(18757..19023)
                     /locus_tag="ACZPCR_08145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008752121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HIR1230882.1"
                     /translation="MLSKKLTVVNPSGLHLRPAGVLSQAAMKFKSDVIIECGEKRIVA
                     KSVLNVMAAGIKCGTEINLICDGEDEEAAMEALSAAIESGLGEK"
     gene            complement(19234..21708)
                     /locus_tag="ACZPCR_08150"
     CDS             complement(19234..21708)
                     /locus_tag="ACZPCR_08150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HIR1230883.1"
                     /translation="MDRGEQERKARSALLEELKNRILFFDGGTGSLLQAAGLGAGELP
                     ETWNISHPETVVKIHRDYLNAGCDMVKTNTFGANRLKFNDHTEFTLREVVEAAVANAR
                     QAAREAGHGWIALDLGPTGRLLKPMGDLEFETAVSMYRETAQTGVQAGADLILIETMS
                     DSYELKAAVLGAKEALESLGRLEGENRIPIFATVIFDGKGKLLTGGTARSVIALLEGL
                     GVDALGVNCGLGPVEMKEIVKEYVQYASLPIIVNPNAGLPRSEGGKTVYDIDGEAFAK
                     AMEELVDLGVSIAGGCCGTTPEHIQKLTERCRGKKQRLPEKKTETVIASYAQAVEIGA
                     DPVVIGERINPTGKSKFKEALRTHNMEYILREGVIQQEHGAQVLDVNVGLPEIDEPAM
                     MEEAVRELQSIIDLPLQIDTADGRALERALRVYNGKPLVNSVNGKKESMETVFPLVKK
                     YGGTVVALTLDESGIPATADGRLAVAEKIYRKAAEYGIQKKDIIIDPLCMTISSDSQG
                     ALTTLEAVHRVKEDLGGKTILGVSNISFGLPQREIINSSFFTLALMNGLNAAIINPNS
                     EAMMRSLHSFRALAALDDNCRDYIEMYGQSSSQAALSAPSQAAKPSGEAVDVKELLKE
                     SVVRGLKEQAAEQAGQALREADPLEIINLCMIPALDSVGKGFEKGTIFLPQLLMSAEA
                     AKAAFEVIKEAMEGSGQTQEKKGVIILATVKGDIHDIGKNIVKVLLENYSYEVVDLGR
                     DVPPEKIAEETVKRRAPLVGLSALMTTTVPSMEETIRLLRKEAPWTRIMVGGAVLTEE
                     YAKSIGADVYCRDAMASVTFAQKVIG"
     gene            complement(21768..22526)
                     /locus_tag="ACZPCR_08155"
     CDS             complement(21768..22526)
                     /locus_tag="ACZPCR_08155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009295951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230884.1"
                     /translation="MTEIRPSEERESQSLQEGGGLAERIADNTSRREAFRYLGYRGNT
                     PDEAAGELMESCIRELCTKLSPRFFAREYPLSRTEEGELCFSCFRVKSRDLGRNLEDC
                     SSVILFGATLGAGADFLLRRYGVLDMGRAVVMQAASAAMIESYCNLENRRLEEEYRKQ
                     GMALCPRFSPGYGDFPLSFQEKFAAALELEKTVGITLTEGFLMMPSKSVTAVIGVKEE
                     RGKNAGASVCKCQTCSKTDCLYRETQDGGAEQPA"
     gene            complement(22581..23438)
                     /gene="metF"
                     /locus_tag="ACZPCR_08160"
     CDS             complement(22581..23438)
                     /gene="metF"
                     /locus_tag="ACZPCR_08160"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002590204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase [NAD(P)H] activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HIR1230885.1"
                     /translation="MKIKDILAQGKPTLSFEVFPPKVQDNYDSVETAVLKIAGLKPSF
                     MSVTYGAGGGTSRYTVDIASSIKAQGVNALAHLTCVSSTREEVQSVLRGLKERGIENV
                     LALRGDIPEGGPLAHDYRYASELIRDIREFDGDFCIGAACYPEGHVESVNKTADIEHL
                     REKVEAGCEFVTTQMFFDNNILYNYLYQIRERGITVPVIAGIMPVTNAKQIKRICQMS
                     GTYLPARFKAIVDRFGDNPAAMKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAEQ
                     IKTSLSEIL"
BASE COUNT         5377 a         6861 c         5004 g         6344 t
ORIGIN      
        1 gttttgaaaa tttcagccct ccgtttccaa ttcaaatagg aaaactgtgc ctaaaaacag
       61 ctgtttttca aatccgctgt ttccgaaaaa tatccctgtt tctgattgaa atgggaatta
      121 acatgtctgc ggtctttccc ctacgcctcg tcaatggcct ttccgatatc atgtctcata
      181 tatttgttgt caaaatcaat ccactctgtc gccttgtagg cgttggctct ggcctctttc
      241 aaatctgagc ctgtggcggt tacgcccaga acgcggccgc cgtttgtaac gattctgccg
      301 tccttgtcaa aggctgtccc tgcatggaac acataatagc cgtccttgtc ctggaagttt
      361 tccagaccgc ggataggaag tcctttctca tacttcacag gatatccgtc ggaagccagc
      421 accacgcaga ctgccgcgtt gtcctcaaac tccagatcaa tctggtctaa ggttccgtcc
      481 acgcaggctt caaagacctc cacaatatcg tttttcattc tcggaagcac cacctgagtc
      541 tctggatcgc caaatctggc gttgtattcc agcaccttcg ggccgttttc tgtcagcatc
      601 agaccgaaga agatgattcc cttaaactct ctgccttcct gcttcatggc gtctactgtg
      661 gcctgataaa tgtgctctct acagaaccga tccacctctt ctgtgtagaa ggggcttggt
      721 gagaaggttc ccatacctcc tgtattcagt ccctgatctc cgtcctgggc tctcttgtga
      781 tcctgggcag aagtcatgat tttgatggta tgtccgtcta caaaagacag cacagacacc
      841 tcacgtcctg tcataaactc ctccactacc atctggtttc cggcagagcc aaacttttta
      901 tccagcatga tgctcctgac gccttcctct gcttcctctc tggtattgca gatgagaact
      961 ccctttccaa gagccaggcc gtccgcctta agaacaattg gcatcggagc cgtctttatg
     1021 tactccagcg ccttttccgg atcgtcaaaa ttttcatagg cagctgtagg aatgccgtat
     1081 tttttcatta aatccttgga gaatgccttg gatccttcca ggatggccgc attctttctg
     1141 gggccaaaga tcctgaggcc tctctcctca aatacgtcca caattccgcc caccagagga
     1201 tcgtccatgc cgaccaccgt caggtcaatc tgatgttcca cggcaaaatc tgccagtttc
     1261 tcaaactcca tggccccgat gggaacgcac tctgcgattc ctgcaattcc tgcatttccc
     1321 ggagcgcagt aaatcttctc tgcctttggg ctctgggcaa ttttccacgc aatggcgtgc
     1381 tctcttccgc cgcttcccac gatcaaaatc ttcatatttc ttccccttcc agacctgata
     1441 cttcctgttt tagcgtccta tctcaatctc cccattggct atcatgtcga tggcctttgg
     1501 aagcaggatc cactctgcct cctccatgac acggcgctgg agaatctccg gcgtatcgcc
     1561 ttccttgacc tccaccggct tctgcagaag aatcggccct gtatctgtcc cctcgtctac
     1621 aaaatgcacg gtagctcccg tcaccttcac gccccgcttc aaagccgctt cgtgaacctt
     1681 cagcccatag tagccgactc cgcagaagga cggaatcaga gacggatgga tattgataat
     1741 gcggtttctg tatctctgaa tcatggccgc cggaatcgct accagaaagc ccgccagcac
     1801 aatgagatcc agctggtatt cattgacctt ctcaagaagg gcctcgttaa actgttctct
     1861 gctttcataa tcccggggag agatgcagac cgcctcgatt ccgtgatttc tggcccgctc
     1921 cagggcgtag gcgcttctgt tattgctgat aactgcctcc accctggcgt ttcggatcgt
     1981 cccgttgtca atggaatcaa gaatcgcctg cagattcgtg ccgccgccgg aaaccataac
     2041 tccgactctt agcataaggt aactcctttt tctccgtcct caatggatcc aatcacataa
     2101 ggcgtatctc ctgctgcctt aatagcctcc atggccttct ctgcatctgc cggatccact
     2161 gccacgatca ttccgattcc catgttgtag gtgttgtaca tcatatcctc ggcaatgtcg
     2221 cccttcttgg ctaacatctt aaagatagcc ggaacctcgt agctgtcctt tctgatcact
     2281 gcgtgggttc cctcttttaa catacggggc acgttctcct ggaaaccgcc gcctgtgata
     2341 tggctgcagg cctttacagt cactcccgcc tttttaaggc tctttaatgc cttcacgtag
     2401 attctggtag gcattaaaag tgcctcgccc aaagtctttc caagctcatc gtaatatgta
     2461 tttaagccct cacgggtcag ctccttctca aatacctttc tgactaaaga gaatccattg
     2521 ctgtgaacac cggtggaagc catgccaatc agcacatctc cagcctttaa gtgttctcct
     2581 gtgatcatat cctttctgtc gcagacacct actgcaaagc ctgccagatc gtagtcttcc
     2641 tccggcatca gtcccgggtg ctctgctgtc tcgccgccga ttaaagcagc ctcagactgt
     2701 aagcagccct ctgccacgcc ctttacaatc tccgcaatct tctccggata attcttaccg
     2761 caggcaatgt agtccaggaa aaataaaggc tctccgcctg cgcaggcaat gtcgttgacg
     2821 cacatggcta ctgcatcgat tccaatggta tcgtgcttat ccataatgat ggccagcttt
     2881 accttggttc cgcagccgtc tgtaccggaa aggagtacag gatcctccat atccttgaaa
     2941 gttgctgctg aaaaggctcc ggaaaagccg ccaaggcctc ccattacctc tggccgcatg
     3001 gttccctgaa catatttttt catcagctct acagacttat atccagcttc aatatcaact
     3061 ccggcgttct tataatccat tacgattctc ctcttttttg ctttttgcgt ttcttcagtt
     3121 ctacaggccg taaacgttta tttcatctgg gccacatact ccttgtagcc gattttgtct
     3181 aacttctcag ccttctccac aacctcgttt ttcatctcct cagagtattt ctttaatttc
     3241 tcaagaagct ctgcgtcgga agctgccaga atcttggctg ccagaatacc tgcgttcttt
     3301 cctccgttga tcgctaccgt ggctaccggg attccggacg gcatctggac gatggagtac
     3361 agggaatcga ctcctccaag atctgaagtc ttcatcggca ctccgataac cggcatgggg
     3421 aacagagccg cgcacatgcc cggcaggtga gccgcttttc ccgctcctgc gataatcacc
     3481 ttgtagcctc tggcctctgc ggatttcgcg tactcgaaga atacatcagg ctctctgtgg
     3541 gcggaaatca ctgtcatctc aaactcaatg cccattttct ccagaaaatc tgccgcctgt
     3601 gccataaccg gcatatctga gtcgcttccc attacaattc ctacttttgc catagtgaat
     3661 tctccttttc cttgtatttt aacattagta attctaatat ttatcaagtt ttatcttagt
     3721 tttactaatt aataatacct gttttatttt cccccgtcaa gacggccgtt tatgaaatat
     3781 acttataagc agatatgacc gcagctgttt aacagccctc cacagtctcc aacggcacgt
     3841 tcagctcctc cgttccaggc agaacaaatc ttccgtcctt tataatgcag acagcgcttc
     3901 cgtcggcgtt taccgcctcc acggtatcca gctcagagta cggaatcgta atgtccgtat
     3961 ggcatccaaa gtaagccttg gacagatcct ctttcctcaa aatagaaatc tcattgtctc
     4021 tggccaccgc ctcttttccg tccggattgt agacaggcgt gtcctccgac cagctgtagc
     4081 aggtgtctcc cactgcgaaa tgggggcctg tcttctctgc tatgagaatt ggaaaacggt
     4141 cggaaattcc atatttgact cccactgcgt aggcagtcgt attggttccc actgcaaatt
     4201 ctcccatagg aagactgtcg tgattcttta aaatcacctg cttcaccagc tttctgcact
     4261 cttcctcatc tgcgaagttt tcgcaggtgt agtccacggt ttttccgttc tcaaaacgga
     4321 tacacaggtt cttaaactga aaatcgccga tatagacgtt tcccacaaac agcgttcctt
     4381 ctgtaccctg aagtaccgga gatgtgaata cctctccgac cggaatgttc acgtccgcca
     4441 cgcagttttc aaaccgggtc tgcttcgccg gatccttaag ctccatcagg ctgattttca
     4501 gatccgtctt atttccccct cttcccgtca ctctggcgta ggacgcctga tccaggacgt
     4561 cgatgatcgt ctgctgaacc cgcttgtaca gctcatagtc cagagtattg atgcggatgg
     4621 tctcctcaaa aatctcctgg aactgatctc caatctgggg aatcgggaac gagatgatcg
     4681 taaagctggt ctcatctccc gggatatagc cgtctaaaat ctgcatggac tcgtttgcgt
     4741 aggcgtgaac cagcttttcc tgcttttcgc tgagagtaaa ggcctctttc ttattctccg
     4801 gctgaaagcc ctcctctccg aaggtctcca gtactgccgg gccgccgtag acagccgcca
     4861 gcgccttgta ctcctcgtaa gctacccgga gcacagaaag ctttctctcc ttaaaggcct
     4921 tatccatgta cagcgcattg tcgtatctgt gatcgtactc gtactggcgg ttgggagaaa
     4981 agccgaaata gccgttggtt cgggatgccg tccggttcat ggttcccact gccgcccgca
     5041 gaaagatggg ggagagcccc atggcctcaa agttctctgc cgcataccgc atcatacgct
     5101 cgaagcccag aggaaagcgc agctgcactg tctgtttttt ggaaagatct cttcccatgg
     5161 cctcgaagcc ttttctgtag ccctctgtga aggtatcggc catctttctc accgtctcct
     5221 cgggaagctc atttaagaag gcggaaatgg atcgctctgt gtcagaaatg tactcgccga
     5281 actggtagag ataccgctcg tctcccagat cgctgttctt tataatcgtt cccgcaaagt
     5341 ccagggacgg atcgagggat tcccggatcc ggtagcttaa ggtcacgtcg cagtaatcgc
     5401 tgacaaacca gtacagaaca gattttaatt ccttctcctc cggctcctcc ccctcgaaca
     5461 ggttgtagac ctcgatgaat acctcctcca ggatcgtcat atctgtcagc ctgctctcgt
     5521 aggcgtagac aatcattccg cggatctctg tgtaaaggaa ggacaaatac gctccgtact
     5581 tctctgtcag ctcccggcag gcataggccg ggttggcaaa gctttcctca taatttcccg
     5641 gcagaatgtc ctcatacagc ctgcggttca ggctgcgaag ctcagaaagc tctgcctcta
     5701 aaagctctcc cgacgcctgg cgctgaaata cctcctcaca cagcagaata aactccgctg
     5761 tcctcttaaa atatcttaca aaccgttctc ccgtggtgtt ctccagagga atctccctga
     5821 ttctggccgc cgccagctca tggcgttctc tcaccgcctc gttttcctct ctgaatttct
     5881 ctgtgtagca aactcccttt tcgtaacgca tcctatcacc ctttcaatcc aattaaaata
     5941 agcacaatcc agaaaatgac aatcaggccg ctgataggcg cccctatctt agccagtata
     6001 tagttttttt cctcctcctg gaacgaagcc cagccataaa tcacgccaaa cacggcgaac
     6061 agaaagctgg aaaagcagac tgccgtaccg cctaccggag tattgccctg gtttctgatg
     6121 ctgattccaa gaccggtcag gcacagaaac agcgccaccg ccgccagtcc caggcagata
     6181 aagccattcc ttgccatagg ctttttaatg tatgaaatct ttttcgtttt ttgagccatg
     6241 aaaagccctc cttatccatt tgagcattgt cacagatacg tacccggccg cccctcctac
     6301 agtattgaga aacatgtcgt ccacgtcgaa gcttcccacc cggaacacca gctgaatcgt
     6361 ctcaatggag agagtcagaa gaaagcttaa aagcagcgta ttgagccatc tctctcccag
     6421 ccttgtaata atgggaagaa taaagccaaa gggcataaag cacaccacat ttcccacaat
     6481 attaagaaga aacgccttag ttcccaccag ctctctgtag gtgtaaaacc gccgtatttc
     6541 tttaaacagc gtcagattgt aatggtactc tgtatactcc gaccggccaa agccgtcgga
     6601 aaaaaacata aaataagtca gcatcagaag atagctgaaa aacaggatcc agcatatttt
     6661 ctgatgggtt ttctctctct tccacatagg ttctccaact aaccgctctc tattatctgc
     6721 aaaaagaatc cttccccgga ttctgaattt tctctttcat ggtaaaaaga gtgttgcagg
     6781 catattccct tcttgcaaca ctcttctggt tcagcataaa gccttttatc aaaatgtaat
     6841 ctctgatttg cgtctcagaa gagccgctcc gcttacaatc gccatcactc cggctgcaag
     6901 ccctgtcaca atcatcacgc ttccgatcac aatgctgcac gcacccgcat tgcgcattgt
     6961 cttatagact ctttccatca gacattctcc tcactatcag ctgcagacag cctattttgc
     7021 tccgtactgc tcgtagtaag cgtcaattgc cgccttaatc tgatcgtcaa tgactacctt
     7081 gccctggcac tcgcggttgt acagatgctc taccacatcc ttcatggaaa caatggcgtt
     7141 tgtggggaag ccatacagat cctttacctc ctcaagcgcg cactttacgc cgcccttgcc
     7201 gacctccata cggtctaagg ataccatcag gcctacgatc ttcacgtctg ccgctccctt
     7261 taccttggga acagtctcct ccatggattt tccggaagta gtcacgtcct caatcataac
     7321 gacgcgatct ccgtcctgca gcttgctgcc taagaagctt cccttatctg cgccgtgatc
     7381 cttctcctcc ttgcggtcag agcagtagcg gatctctttt ccgtataatt cgctgtaggc
     7441 gatagctgtc actacgctta aaggaattcc cttataggcc ggtccgaaca gcacgtcgaa
     7501 atcgtctccg tacacgctgt ggatggctct tgcatagtac tctcccagct ttttcagctg
     7561 agagcctgtc acatagccgc ctgcgttcat gaaaaacgga gactttctgc cgctctttaa
     7621 cgtaaactcg ccgaatttca gcacctggct ctctaccata aaatcaataa attcctgctt
     7681 atagctctcc atctctctgg aacctcctag atttacaggc ttctatcctg ttcgttttct
     7741 tccacgtttt tcacgcgttc tattttacaa tgccgatcag gctgttaata tcctccacct
     7801 gatacttctt catgtaggcc tccatgccct ccacgatctc ctgggttgcg taaggattgt
     7861 ggaaattggc ggttcccacc gatacggctg tggctcctgc catcataaac tcaatggcgt
     7921 cgtctgcgca catgattccg cccattccga taatcggaag cttcactgcg ttagccacct
     7981 gatataccat gcggacagcc accggcttaa tggccggacc tgacaggcct cctgtcttgt
     8041 tggcaacggc aaaggcgcgc ttatggatat caatcttcat gcctgtgatc gtattgatca
     8101 gggaaagcac gtccgctcct cccgcctcgg ccgccttggc catcaccgta atgtctgtga
     8161 cattggggct cagcttcatg atcaccggct gtctggcgtg gcgcttcacc tctctggtaa
     8221 tcgcctccac cgccttggga tcctggccga aggcaatgcc gccctccttg acgttagggc
     8281 aggaaatgtt aatctccagc atatccaccg gctgatcgga aagcttctcc accacgtcga
     8341 tgtaatcctc tgtggtcttt ccgcagacat tgacaataat cttcgtatca aactgcttta
     8401 aatagggaat atccctcttg gcaaacacgt cgaaaccagg attctgaagt cccaccgcat
     8461 tgatcatgcc gccgtaggtc tccgcgatgc ggggagtggg atttcccggc cacggcacgt
     8521 ttgccacgcc ctttgtcacc actgcgccca gacggtttaa atccaccatc tcgccgtact
     8581 ctgctccgga gccgaaggtt cccgacgctg tcataaccgg gttcttcagc ttcactcctg
     8641 ccagattgac cttcatattc attacagctc cacctcctcg gccaggaata cgggaccgtc
     8701 cttgcagatc ctcttattat gtacattcgt gtggtgatcc acgtccttgg acttgcagac
     8761 gcaggccagg caggcaccga ttccgcaggc catcttctcc tccagagaga tgtagcagcg
     8821 gatatggttc tgggccgcgt actccttcag agcccgcagc ataggcgtag ggccgcaggc
     8881 gtacatcacg tcggcagtca ggccgtgctc cctaatcgca tccagcacgt ttcccctggt
     8941 gcctgcgctt ccgtcctctg tggccacata tacctggccg taagcctcaa actccttctt
     9001 taagaaaaga tttgcgtctc tgtatcctaa aaccatctgt ttctcacagt ttaactgttt
     9061 ggcaagctct aacatcggcg ggattccgat tcctcctccg atgaggaaca ccttctcccc
     9121 ctcctgaggg aagccatttc ccagcggtcc catgatctcg atggagtctc cggactggta
     9181 atgggaaaat tcttctgttc ccgctcccgc gattctgtat acaatgcgca ggcggccctc
     9241 ctccttatca atttcacaga tgctgatagg ccttggcaga agcctggatc catcctttgt
     9301 gtaaacagaa ataaactgtc ccggcttcgc gtctgcagct gcctttgtgg caatccacat
     9361 gctgtaaata tccggagcca gcatttcctg gctgtataca acagccgtct ccttaatctg
     9421 tgccatctct ctctcctgta tctgtattct gaagtctgca ggttaagctt ttaaaagaaa
     9481 tccctacagt acgctgttaa tatctgcaat catgtcaata acagcctgtc tggacgcctc
     9541 gccgaaatgc ttcggtccaa acttggcata cgcgtctttc ttgtatgccg cgataatgcc
     9601 tctggaggaa ttgacaactg ctcccagtcc gtcctcgttg aagcagtatt ttaaatcctc
     9661 tgccgtgccg ccctgagcgc cgtagccagg aaccaggaag taagttctcg gcatcagctt
     9721 tctgagcacc ttgctcatct ccgggtaggt agcgcccaca acggctccca cgttgctgta
     9781 agctccgtcc atggaagcgt cgccccactc tactaccttc tccgctacca gctcgtacag
     9841 cggacggccg tcaattaagc ggtcctggaa ctcgccgctg gaaggattgg aggtcttcac
     9901 cagcacgaaa ataccgcggt cgcactgatt gcacacgtcc acgaaaggct tcacgccgtc
     9961 tgttccaaga tatgggttaa ctgtaatgta ctcggtattg aagccgctta aggtctggct
    10021 tcccacctga accgttccca ggtgtcctgt ggcgtaggcg gcggaagtag aaccgatgtc
    10081 gcctctcttt acgtctccga tcacgatcag gcccttctcc tggcagtatt tcaccgtctt
    10141 atcgtaggct gccagtcccg gaagaccgaa ctgctcgtac atggcaatct gaggcttaac
    10201 agacggaatc agatcgcagg ttgcgtccac gatttcctta ttaaactgcc agatggcctc
    10261 cgcagctccc tctaaggtct cgccaaactc agcgaacgcc ttctttgtca catgctccgg
    10321 aatataactt aacatcggat ccaggccaac acagatcgga gcctttgtct tctgaatttt
    10381 ttcgattaat ttacttacca tcttatcctc ctgtttttaa acacgctctg gtttaattct
    10441 aaattatttt atcataagta cagtagggga tcaagtacgg ctttgcgcct tccacgcccc
    10501 tactggcgga tggcgagagt cgccacatac acgccgtttt tataggattt ggccgcaaac
    10561 tgctcctctg tggccgtctc cagctccagc cacagctcct ccgcagccag catgatatgg
    10621 gacagcataa cgcccactga aaagtcccgc atcagtcccg ccgcgggaac caggctgcga
    10681 aagccctgca gaacgcctga gtccttcttg gcaaatacat agatccgatc tgtgtagaca
    10741 atgaaccgcc agggctggga gttaaatgca gacggagcca gtctggccgc ctttaatacg
    10801 gttttcatag tctcccctgc ctcctcctta aacacgcaga gctcgtttaa gggcaggcgc
    10861 ttcgccagag agctctcccg gaacagcttg ccctccggat agccgaaggc cacaaccatc
    10921 acctggcgtt ttccgtcgct tcgctttctt ttaaccgtgc tgcctcccag gtagcaggtt
    10981 cccagtccct ttacagtcat gtaaaggaca atctgctcca taagatagcc cccgtttctc
    11041 ccatagccct cctcaggctc cgagtagagg acaaaatacc agggggcctc taccttccag
    11101 acgcccttca tcggcgcttt tttgtcacgg ttgtcaatta tctcaaaatc cacctggatt
    11161 ctgtcgttta gcggggaagc cgtcctggca aacgccagaa tctgttcccg cagtttttct
    11221 gtcacttcct tatcagagta tttccgcact gaatggcgga cgcctatcgc ctcatacaga
    11281 ttcattctcc cttttccctt tccgcctctt ctcagacgcc tgtctgcagc ggccttaaat
    11341 cattcctgaa ataagcggaa ccacaattac agtcagtacg ccggccaccg ctatggcaag
    11401 gcttgacatg gcgccctcca cttctccgag ctccaatgct ctggctgttc cgatggcgtg
    11461 agccgatgtg ccaagagcca ggcccttcgc catgggttcc tctattttaa gcagctggaa
    11521 aaccagatct gctataatat ttcctataat tcctgtcaca ataatgctca caacagtcag
    11581 cgtcacaatg cctcccgcct cttcgctgac tcccatgccg atagctgtgg taatagactt
    11641 gggaagcagg gtaacgtaga tctgatgatt caggccaaaa gccttagcca tcacaagaac
    11701 acttcctgcg cttcctaaaa caccagtcaa aatggacgct cccactgcca gtttattatt
    11761 cagcaaaagc tccagctgct tatagagggg aatcgccaga caaactgttg ccggcgtcag
    11821 aaaatagctt aaatactctc ctcccttatt ataggcttca taactcacat gaaatacctt
    11881 taaaaataaa ataacggcaa tgatcgccac caaaagggga tttaatatag aaagtcccgt
    11941 ttttttcttc agccataccc caaacaggta ggctcccaca ctgagcagca taccaaaata
    12001 cagagatgtt ccagctattg attccatctt attcttcctg tccttcctgc ctattttttc
    12061 tgataatgtg ctgagccgtc tttcctgtca cagccatgac aaaaattgta gacgcggcgg
    12121 tgataaccgt cagaggaatc agcacactct ccattacgtc ccagctgttc atcaatccta
    12181 cgcctgcagg aataaacata agcggcatag tgtcaagaaa aaatccgccc ggctcctcca
    12241 catcctccag cttcaccgcc ttcaaacaca gagcccccag aagcaggaac agcccatata
    12301 ccccggatgg gattggaagc ggaagcagga cattgagaaa ttcccctatc atagtgatgc
    12361 cgaaaataat tgtaataccc ttgatgaatt tcatcctcag tcctccttat ttttgtaaac
    12421 tcttttattt tatcactgtg attttcatcg cacaatagaa aaaattctta tattttgatt
    12481 gaaattcatc tgctctatgg actatactta taagaaaagt taaatttcag gagtttttta
    12541 tggatatcat acgaacgagc cttctttctg ccggacaggc agacgagata aaagaacttt
    12601 taaatggatg cagagattcc aagggacaga ctcccttttt cccttttgag gacggagatc
    12661 tgttttatct gctttttaca gaaacggatg ataacgctgc cagcagaatc ttagcctgcg
    12721 cggcggcttt aagctttttt gaagagtccg gcgcgcccta tgcagagtgc tctgccttca
    12781 ccaggcctgt tcttcggcaa aaaggatatt tctccctact ttttgacgaa ttatcccagg
    12841 atattgagga ggtggatctc tactttcctg taactgatcc agaacctgga accttagctg
    12901 ccctagcttc cctggaagcg gtccgcgaca gagacgaata caggatggaa ctggagctgg
    12961 agctggaatg tgcaaaggct ttttccggcg ctccttttca ggagacgtct gcgcctggca
    13021 cctggaaagt tccgggcagc cgcctccata cccagtggga ggaaacagaa catgattcct
    13081 ttctcctctc cttttaccag gaagagaaag ccgttggaaa ctgctgcctg tccttttttg
    13141 gtgacagtgc ctgtttctac agttttgaaa tcaaagagga gctgcgggga ctgggactgg
    13201 gctgggaggc tctttcactc actctctcac tccttctaaa gggacttccg cgccctggct
    13261 gcagacgcct ttctctccat gtatcagggc ttaacacacc tgccatatcc ctgtaccgga
    13321 aggcaggatt ccatattaag gagagcttat cctactatct atactagaaa tggagggaaa
    13381 ctgagttatg attcaataca gaggtcctgc gcgaaaacaa aatagtatct gtgctttcct
    13441 atcagccgca gtcatgcttg ggcttccatg gcttgcgata accttcgttc ccgctgacag
    13501 cggtatggcg gctttgctgc ttatattttt catcataaat cctgccgctg cagccgcatc
    13561 aggcattttc gccggagaaa atatctcctc ctcctggttt cagcctctgc ttttaacagg
    13621 attatttatt tcaggaagcc ttatattcct tgatatgaaa agtcaggatt ttatgtttta
    13681 cgggatcctg tatcttgtga ttggatatat ttttatggca gtcactgcat tcaaaggaaa
    13741 aaaacggcag tttccgccct gttaatgcct ttcaccacaa ataaaaaaca taaaaagaaa
    13801 gaaacaagtt ttccagtggc tttcagcgga acatggaaaa cttgtttctt tttttaatat
    13861 gcttttaaat atgcttctcc tataatctct tacacgacct tctcccggcc tttattgata
    13921 tcgtactcct tcatctgctc ccgatcttca atcttccggc ggatttccag catcttccag
    13981 tcggttccgg caatgacttc cgcgcaccgg cgcagatcct ctccaatctc ggccgcttcc
    14041 tcctccgtca tttccttttt gtacttcagc tggtgatcca ggctggccca gaaatccatg
    14101 gcaatggtcc ggatctgcac ctcagcccgg atgtactgct tacagttgga aaagaagact
    14161 ggaatctcta aaatcatgtg gtagcttctg tagccattta ccttgggact ccttatgtaa
    14221 tcctttatgg caatgacccg gatatcatcc tgtctggcca gcatacggct gacgtcgtaa
    14281 atatcgtcga taaaagaaca gatcacgcgg actcccgcaa tatcgtccag attctctctc
    14341 atagactcta ctgtcaccgg aaggcctctg cgcttcagct tctcaaaaat actctgcggc
    14401 ttctttacgc gggatcggat catctcaatg ggatttctct ggtttctcac ggaaagctcg
    14461 tcgttcagca cctccagctt tgtcttaagc tccctgattg cgcaggaata cttcatcatc
    14521 tcattcctga actctatggc ctcgccgatc aggctctccg gcacttctac ctctctcggt
    14581 ccgatcacaa cggactggtt cagctcgctg ttcggattct ggttaaaact catatcgcac
    14641 acctctggtt cgtcattctg ttgttctttt actattatag ctgaaaagca tacgggaaac
    14701 aatgaatctt tcattaattt tacctaaact tccaggcacc cttctgataa atcagaaatc
    14761 caaaaaaatt tctgaaaata atgccgaaac caaaagctcg tgtttacaaa caaatgcttt
    14821 aatggtatgc tatccctaga taataccaga taggaggcaa tttatgaaaa atttaggtta
    14881 ttacaacgga actttcggcc ctcttgagga aatgaccatt cccatgaacg acagagccgg
    14941 gtatttcgga gacggcgtgt atgaggcgac tctggccaga aatggaaaaa tctttgccct
    15001 ggaggatcat ttaaaccgtt tctacaacag cgccggttta atcagaatcc cggttcccta
    15061 caccagacag gagctgaccg atatccttta ctccatgctg gaaaaaatgg atgattctga
    15121 agttctcgtg tattggcagc tgaccagggg aaccgcgatc cggaaccaca tcttcccgga
    15181 cgcttctgta aagccgaatc tgtggattac catgaagcca ggaaagaact ccaaccctga
    15241 ccgtgcctta aagctcactg ccaccgagga tacccgcttc ctccactgca acattaagac
    15301 actgaacctt ctccccaacg ttatggcggc acagaaggct gaggaggccg gctgcgacga
    15361 gtgtatcttc caccggggcg atattgtaac cgagtgcgcc cacagcaacg tctctatttt
    15421 aaaggacggc gttttcatca cccatcctac ggatcactac atccttccag gcatttccag
    15481 aatgcacctg attcaggagt gcaagcgtct gggcattccg gttgacgaaa ctccgtttac
    15541 catgaaagag ctttatgagg ctgacgaaat catcgtatcc agttccacca agctgattgt
    15601 gagagcctgc gagctggaag gaaagccggt aggcggaaag gctcctgagc tgttcaaaaa
    15661 acttcaggac gcttatctgg agcgcttcca gaaagaaacc gagcagtaat tttctgacaa
    15721 agcacagctg atatcagaaa ctgatattaa aaaggacatg ttcccgtttg aatcttcatt
    15781 ccggaacatg tcctttttac ttcatggaaa atggaatcct gcgaaggatt cgctctcatc
    15841 cgttctacat cttctcaatg atgtctgcag cctcatccag ccatggagac tctacgtact
    15901 ctaccacgcc ctgatccacg ctgtctgcaa tctttggatc aatcggaagc ttggctaaca
    15961 tcggaatgcc gtactctttg gccacttcgt ctgccttgct ctctccgaat acagaaattt
    16021 tgcggccgca gtccgggcag agcagatagc tcatattttc caccagaccg ataatcggca
    16081 cgttcatctt cttcgccata ttgactgcct tcgccacgat catggaaacc agatcctgcg
    16141 gggaggtaac aatgataata ccgtctaacg gaagagactg gaagacagtg aggggtacat
    16201 cgccggttcc cggaggcata tccacaaaca tatagtcaat atccttccag agcgcctgtc
    16261 cccagaactg cttaatcact ccgcctacaa tggggcctct ccagataacc ggatccgtct
    16321 catgctccaa aatcaggttg gaggaaagca tctgaattcc tgtctggctt tcgcagggaa
    16381 tcatcagttc atcctctgtc actcccactg tctcgtggac gccaaaggcc ttgggaatag
    16441 acggccctgt aatatccgcg tctaaaattc ccactctgtg gtttctcgcc cgcattttac
    16501 atgccatcag ggacgtaacc agggattttc ccactccgcc cttgccgctg actactccga
    16561 ttaccttctt aactgtgctc tgtgggttta acggctctaa aaaactagcc ggctgtctgc
    16621 tggcgcagtc ggcgctgcag ctgccgcagt catgattgca ttcgctcatg tcatttctcc
    16681 tctctttatc tgtttatttc caaacactcc tgcagtttta ttttaagcag aaaatcattt
    16741 taattatacc atatctgcct gccgtttgtc ccgttctttt tccagtgcaa aaagctttga
    16801 aatgctttct ttcatctgta tgccaaaaaa gagagaaaac tttccagcgg cttaggtgga
    16861 gcgcagaaag tttttctctc ttttcattac cctttttatg ctttccccgg actgccaaat
    16921 cgccggatcg cccgcactag gccgaaatcc tccagctttt tagctataat atagaagaga
    16981 aaggaatcga cgggccacat aaccatattt ttcacaaacc gcggtccgat aagcacggaa
    17041 atgccctttc catacaggat gcttaagcac caggtattta aaaatacgtt gcagattaaa
    17101 tccacgcaga gcgtcaccgc cagcactctg gaaaaggtga gcgtcctgcg gtagaaaaag
    17161 gttccgtaaa tcagcgccgc cagcatcgtg accatggtaa aaccagggaa aaaggctccc
    17221 gtaggcttgg ccacaaactt gaccagatcc agcagacagc cgtaaaccac acccagaacc
    17281 ggcccgaaca gataatagac aaattcattt gccacgcttc caaagccaat cttcagatag
    17341 ggtcctgcct cgatggtaaa atatcccaga accaccgata ctgccatgaa catggcagct
    17401 gtagtcagag agcggacatg cctgacttct ttccatgact gcgcgtacac ttccgccagt
    17461 ttcttcataa aaaaatacct cctttcgcag aatctcaaac cgcaccaggg aggtaatttc
    17521 gcgctgtcct ccagtcagga aaaacagcag tatattccga ggatgcagcg ggatgcgggg
    17581 aaccgaccgc aaagaagttt ctgaaaatct ctttttcgtc cggctggcaa ctccctgtcc
    17641 agccggcact taacgcctga tcccctactc tgctttcttg tttttttgta ctctcagtat
    17701 atcacacaga cgatactttt caatcccttt cttgacaaac catgcaataa aaattcccag
    17761 ggccgctccg cttaacacat cggtaggaaa atgtacaaac aggtacattc tggaaagtcc
    17821 gatgagggcg gcgaaaatca gaaaagcggt tccccacttc cgattgacca gaaaaatgct
    17881 tacagcggtc tcgaaagcgg ccagggtatg gccggatgga aaggaataat cgtgaggaac
    17941 cggaatcagc aacggcaccg acgcgtctat ccagcatggc ctgggccgca taaccagatt
    18001 tttcaggcac agatttccca caatcatccc gcaaagcagg gacaaaagca ctgctgttcc
    18061 tgctctgcgg gttctgggaa tgaaaaaaag cgccgctcca aggagaatga aaaaccagcc
    18121 cttgtctccc agatgcgtga tcgcctccat cgcctgatcc agcaccggac tgcgaagctc
    18181 ctgcagccag tacagaattc tgaattccat atcaagcatt ttcattctcc tcattctctt
    18241 tcttgaattc ccggaatgcc ttgtccatct caatgtaatt gcgcttcagg gaaaccggct
    18301 ttccgtctct ggtcaggaag cagtggcggc tctctcccac acagcgcacc tgtcctgtcc
    18361 tgcagtctaa caccgtgtac tcaatggtca tcttgatgcc gttgtactct ttcagatttg
    18421 tgataatcct gactgtctct ccgaaacgtg tcatgctctt atactcgcag tgaatggaaa
    18481 tcaccgggct gatcacgcct gcctcttcca tggcgtcgta gcccatcccc agctgctcca
    18541 tcatgtggac tctggcttcc tcaaaccagc ggatgtagtt ggaatgatgg ataattccca
    18601 tctgatctgt ctcatagtac tgtgtcttgt gttcataaac ctcatatttc atagccaaat
    18661 ctcctttcat gatcacagct cacaggcttt ttcgtcttct ataaagcaaa agtgtgcgcc
    18721 tcttcgcgca cactttcaca cccatataaa acggaattat ttctcgccga gtccgctctc
    18781 aatcgctgcg gagagagctt ccatcgctgc ctcctcgtcc tcgccgtcgc agatcaggtt
    18841 aatctctgtt ccgcacttga ttcctgctgc catgacgttc agcacgctct ttgccacgat
    18901 tctcttctcg ccgcactcaa tgatgacgtc acttttgaat ttcatcgctg cctgggataa
    18961 aactcccgct ggtcttaagt gcagaccgga cggattcaca actgttaatt tcttagataa
    19021 cataagctcg tctcctctac tgtttcgttt cctcggagtc tctaactcct cgtttgatat
    19081 agaaaattct attacaattt ctcttttctg tcaagtaaac tttatttctc tttctgtcag
    19141 aaagccgccc caaggccctc tattttttgt gcattgtgca acatgatttc tgattgatga
    19201 tttttatttt tatgcgtttt atctatcttt tttctatccg attaccttct gggcaaaggt
    19261 gacggaggcc attgcgtctc tgcagtagac gtctgcccca atggatttcg catactcctc
    19321 ggtgagcacg gctcccccca ccataatcct ggtccaagga gcttcttttc taagaagacg
    19381 gatggtttcc tccatgcttg gaactgtggt agtcatgaga gcgctgagtc ctaccagagg
    19441 cgcgcggcgt ttcaccgtct cctctgcgat tttctccgga ggcacgtccc gccccagatc
    19501 taccacctcg tagctgtagt tttcaagcag caccttcaca atattttttc caatatcgtg
    19561 gatatcgcct ttcacagtgg ccaggataat cacgcccttt ttctcctgag tctgtccgct
    19621 tccctccatg gcttctttga ttacctcaaa ggccgccttg gccgcctctg cgctcattaa
    19681 aagctgggga aggaatatgg ttcccttttc aaatcccttt cctacagagt ccagggccgg
    19741 aatcatgcac agattgataa tctccagggg atccgcctcc cttaaagcct gtcccgcctg
    19801 ctctgccgcc tgctctttca ggcccctgac aacgctttct ttcagaagct ctttcacatc
    19861 cacggcttct cccgatggtt tcgctgcctg ggacggcgct gacagagctg cctgggaaga
    19921 agactggccg tacatttcaa tataatccct acagttatcg tcaagcgcag ccagcgcccg
    19981 gaagctgtgc agggatcgca tcatagcctc tgaattcgga ttgataatcg ccgcgttcag
    20041 gccgttcatc agcgccagcg tgaaaaacga ggagttgata atctctcttt ggggcagtcc
    20101 gaaggagata tttgacacgc cgagaatggt ctttcctccc agatcctcct tcacacggtg
    20161 cactgcctcc agagtagtca gagctccctg ggaatcagag ctgatggtca tgcagagagg
    20221 atcgatgata atgtccttct tctgaatgcc gtactctgcc gctttccggt aaatcttttc
    20281 tgccaccgcc aggcgtccgt ctgctgtggc aggaattccg ctttcatcca gagtcagggc
    20341 taccactgtg cctccgtact ttttcaccag cggaaatact gtctccatgc tctctttctt
    20401 tccgtttaca gagttcacaa gaggttttcc attgtagact ctgagagccc gctccagggc
    20461 cctgccatcg gccgtatcaa tctgcagcgg caggtcgata atgctctgaa gctcccgcac
    20521 cgcctcctcc atcatggcag gctcgtcgat ctccggaagg cccacgttga cgtccagaac
    20581 ctgggcgccg tgctcctgct ggatcactcc ctccctgaga atgtactcca tattgtgggt
    20641 tcgcagggcc tccttaaatt tagattttcc cgtagggtta atccgctctc cgatcaccac
    20701 cggatccgct ccaatctcca ctgcctgggc ataggaggca atcactgttt ctgtcttttt
    20761 ttccggaagc ctctgcttct ttcccctgca ccgctctgtc agtttctgaa tatgttccgg
    20821 cgtagttccg cagcagccgc ccgctatgga aacgcccaga tccaccagct cttccatggc
    20881 cttggcaaac gcttccccgt caatatcata gaccgttttt ccgccctcgc ttctgggaag
    20941 tcctgcatta ggattcacaa tgattggaag agaggcatac tggacgtact ctttcacaat
    21001 ttccttcatc tccaccggtc ccaggccgca gttgacgccc agcgcgtcca ctcccagccc
    21061 ttccagcagg gcaatgacgg agcgggccgt tccgcctgtt aaaagctttc cttttccatc
    21121 aaaaatcacg gtggcaaaaa taggaatcct gttctctcct tccaggcgtc ccaggctttc
    21181 cagggcctcc ttggctccca gcaccgccgc cttcagctca tagctgtcgc tcatggtttc
    21241 aatgagaatc agatctgctc ccgcctgtac gcctgtctgc gccgtctccc ggtacatgga
    21301 aacagccgtc tcaaactcca gatctcccat gggctttaac agtctccccg taggccccag
    21361 atccagcgca atccagccgt gtccggcttc ccgcgccgcc tgcctggcgt ttgccacagc
    21421 ggcttccacc acttccctca gcgtaaattc cgtatgatcg ttaaatttca gacggttggc
    21481 tccaaaggta ttcgtcttta ccatgtcgca gcctgcgttc agataatccc ggtggatttt
    21541 cactactgtc tccggatggg agatattcca tgtctccggc agctcgcctg ctcccaggcc
    21601 ggctgcctgc agaagacttc ccgtgcctcc gtcaaaaaac agaatcctgt ttttaagttc
    21661 ttctaaaaga gcggatctcg cctttctctc ctgttcccct ctgtccatct ctatttcctc
    21721 gcattctcta agtctcgttc ctctgctttc gcaaaagcgc cgtttcctta cgccggctgt
    21781 tctgccccgc cgtcctgtgt ctcccggtaa aggcagtctg ttttactgca ggtctggcac
    21841 ttgcagacag acgccccggc gttttttcct ctctcctctt tgacgccaat caccgctgtt
    21901 acagacttgg acggcatcat cagaaagccc tctgtcagag taattcccac cgtcttctca
    21961 agctccagag ccgcggcaaa tttctcctga aaagacaggg ggaaatctcc gtatcccggg
    22021 ctgaatctgg ggcagagagc catgccctgt tttcggtatt cctcctccag acggcggttt
    22081 tccagattgc agtaggactc tatcatagcg gctgaggcgg cctgcatgac gacggcccgc
    22141 cccatgtcca gaacgccgta tcgccgaagc agaaaatcgg ctccggctcc cagcgtcgcc
    22201 ccaaataaaa tcacagaact gcagtcctcc agatttcttc caagatccct gctttttaca
    22261 cggaaacagg aaaagcaaag ttccccctcc tctgtgcgtg aaagaggata ttccctggcg
    22321 aaaaagcggg gcgaaagctt cgtgcagagc tcccggatac agctttccat cagctccccg
    22381 gccgcctcat ccggcgtatt tcctctgtac cccagataac ggaacgcctc tctccggctg
    22441 gtattatctg caatcctttc agccagtccg ccgccttcct gcaagctctg gctctccctc
    22501 tcttctgagg gtctgatttc tgtcataacc gctccccctc acctctttca gcttcctgaa
    22561 agcctttccc aaaccgtctc ctacagaatc tctgacaggc ttgtcttaat ctgctccgcc
    22621 acatccggct tattcatgga gtagacgtga atgccattca catggttggc aatcaggtcg
    22681 atgatctgct ctgtggcgta ggcgattccc gcctgcttca tggcggccgg attgtctccg
    22741 aaccggtcta caatggcttt aaatctggct ggaagataag ttcccgacat ctgacagatg
    22801 cgcttaatct gctttgcatt ggtcaccggc atgattcccg cgataacagg caccgtaatg
    22861 cccctctctc tgatctggta cagataattg tagagaatat tgttgtcaaa gaacatctga
    22921 gtggtcacaa actcgcagcc tgcctccacc ttttcccgca gatgctcaat gtcagccgtc
    22981 ttgttgacag attccacatg gccctccgga tagcaggcgg ctccaataca gaaatctccg
    23041 tcaaactccc ggatatcccg gattaattca gaagcgtaac ggtaatcgtg agccaggggg
    23101 cctccctccg gaatgtctcc tctcagagcc agcacgttct cgattccacg ctctttcagg
    23161 cctctgagga cgctctgaac ctcctccctg gtggaggaaa cgcaggtcag gtgagccagc
    23221 gcgttgacgc cctgggcctt gatgctggac gcaatgtcca ccgtatatct gctggttcca
    23281 cctcccgctc cgtaggtaac gctcataaag gacggcttca gtccggcaat ttttaacacg
    23341 gccgtctcta ccgaatcata attgtcctga accttgggcg gaaacacctc aaaggaaagc
    23401 gtcggctttc cctgggctaa tatgtcttta attttcattt atttacacct ccgtctgaat
    23461 gcaggcgttt cttttctctg ctttcagtat ttttccctct agtataccac aggcttgata
    23521 ttttttctac aatcattatt catttttctg catttgtgct aaaatgattc ttgaccaaaa
    23581 caggca
//
LOCUS       DBMDUW010000038        22906 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1463_length_22906_cov_3.115633, whole genome shotgun sequence.
ACCESSION   DBMDUW010000038 DBMDUW010000000
VERSION     DBMDUW010000038.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 22906)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 22906)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22906
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1463_length_22906_cov_3.115633"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            102..452
                     /locus_tag="ACZPCR_08165"
     CDS             102..452
                     /locus_tag="ACZPCR_08165"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230886.1"
                     /translation="MAEVVSWYYPETEALTIYSQDSDTYEFQRKAEASLREIFTSRTP
                     VPVSYKSNDAILCQLFRDGKINIENLGDYRKDIRKITYSKIQDDHSVILVTEVVDNDL
                     FLALVQDTSVHIIF"
     gene            complement(589..2328)
                     /locus_tag="ACZPCR_08170"
     CDS             complement(589..2328)
                     /locus_tag="ACZPCR_08170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1990112 - RQC complex [Evidence IEA];
                     GO_function: GO:0001968 - fibronectin binding [Evidence
                     IEA];
                     GO_process: GO:0072344 - rescue of stalled ribosome
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein"
                     /protein_id="HIR1230887.1"
                     /translation="MAFDGIVIASLVHEFNQTIAGGKIAKIAQPEKDELLFTIKNNRE
                     NYRLLLSVNPSLPLAYLTDKNKNSPLTAPNFCMLLRKHIGNGKIISITQPGLERAVEF
                     EIEHLDEMGDLCRKRLIVELMGKHSNIIFCTSEGMIIDSIKHISAQVSSVREVLPGRE
                     YFIPQTACKLNPLEAGEEEMAAVMAQAPEPVGKALYSHFTGISPVMAEEFCHLASIES
                     SIPAAELSEAERIHLSRTFSLAMESVKGGQFSPCILYKGEEPVEFSALAFTALPADCC
                     LKEFSSMSQVLETYYASKNVITRIRQKSSDLRRIVQTALERNYKKYDLQLRQLKDTEK
                     RDKFRIYGELLNTYGYELAGGEKELSCLNYYTNETIRIPLDETKTAQENAKRYFEKYN
                     KLKRTFEALTELTEETKREIDHLESISAALDIALKEEDLTQIKMELTEYGFIKKHGPN
                     MKKQKVVSKPFHYLSSDGFHIYVGKNNYQNEELTFKLATGNDWWFHAKGIPGSHVIVK
                     SEGKELPDRVFEEAGALAAYYSKGRDNEKVEIDYIQKKNIKKVAGAAPGFVIYHTNYS
                     LVAVPGNKLEEVN"
     gene            complement(2356..3882)
                     /gene="citX"
                     /locus_tag="ACZPCR_08175"
     CDS             complement(2356..3882)
                     /gene="citX"
                     /locus_tag="ACZPCR_08175"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008398103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050519 - holo-citrate lyase synthase
                     activity [Evidence IEA];
                     GO_process: GO:0051191 - prosthetic group biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HIR1230888.1"
                     /translation="MNHFYSDKSLKNGADSGRLCRPVSVEDMMEARERRARLQEQLIG
                     TYQVPVVSFTLNIPGPVKILPGTEEFFRRGSESVRQALKQASVPVLFETQLREHTGLE
                     LFLCADSKPETLKQITSSLEEETAGGRLYDIDIIRTDKSKVSREEIGLPGRRCLLCGE
                     PAHACSRSRKHTVEDLVSHIQQLMAEDAFLNHLYLAARESLTDEVSATPKPGLVDRLD
                     NGAHRDMCCETFLKSAGAVAPYIRTMAEQGIHFSRQTADEDKKEPDLPLLFSQIRKTG
                     LLAETAMFDAAGGVNTHKGIIFSMGILAASAGFLFGQSRLNLPSLNLSELLSLAGKLC
                     RKEIQEDFSALEQRRQQADAKSGTGNVHFSHGEKLYLAYGCRGIRGEASDGFPALSSI
                     SMAAFSSALEALGGKTEISGDIWNRACLQTLLSLMAQVEDTNVIHRGGMDAALYVREQ
                     ARKALLDGGAVTDGWQARLSSMNQDFIEKNISPGGCADLLALTVFLLRLQGISPEERF
                     "
     gene            4042..4899
                     /locus_tag="ACZPCR_08180"
     CDS             4042..4899
                     /locus_tag="ACZPCR_08180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016297957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STM4015 family protein"
                     /protein_id="HIR1230889.1"
                     /translation="MAKSKKYFYDYDMAEEGKGPRTMIPEILADSEFPSLTELVIGDW
                     GTSWEEGCQQMIDDIVANKEKFSHITSLFIGDMDFEECEVSWIIQGDYSRIYEAMPQL
                     KSLTIKGSTELRLGAISHEGLEELTIICGGLSEDVFKSIEQAHLPNLKKLLLYIGVED
                     YGFDGSIDTIRSLLANSDFPRLSYLGLTDSELQNEVAAAVLESKYIGQIETLDLSEGT
                     LNDKGGEVLLAGLPGYPNVKKLDLHYHYMTEEMEGKLKALPLELDVSERNLPDEYNGE
                     LWMYPMLTE"
     gene            4896..5990
                     /locus_tag="ACZPCR_08185"
     CDS             4896..5990
                     /locus_tag="ACZPCR_08185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002603846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STM4014 family protein"
                     /protein_id="HIR1230890.1"
                     /translation="MRQAHLLGVSGHKRTRYFQKAAAEAGLFFGFSDWKLFLEHPSLP
                     DQDLFVKLDPFPAAGVFLQDLEQNVRAYRTALERLEESEKLRRQSGLQTQWLNTPGGI
                     LSALNKRECQSRLLQAGIPVTGEGLQIQGKNGFSGGEELLSWMAEQRESQIFLKPVWG
                     SGAAGVCALRFHPEKGTGALYTCAASAEDNLRGQSLINTKKLRVLRDRKEIAAFLDQL
                     LSMDCLAERWYPKASFQSYSYDLRAVWQFGQLDFLLARLSKGPLTNLHLNNHPLPARE
                     LGLPLSVREELEELCRQTSLVFPGLMSFGADILLERGSLRPRIIEINGQGDLLYQDIY
                     QENRIYRRQAEVMKAWMEEQGDKFETRRTI"
     gene            5968..6855
                     /locus_tag="ACZPCR_08190"
     CDS             5968..6855
                     /locus_tag="ACZPCR_08190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016291013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="STM4013/SEN3800 family hydrolase"
                     /protein_id="HIR1230891.1"
                     /translation="MKPDVPFEQFGAKEAPSFDMNEVAGKKDILFICLDTLRYDAAKE
                     EEEKGNTPVLNQYGPWQKCQAPGNFTYPSHHAMFAGFLPCPWEARSIADRSMLFFPKN
                     IGMGRMTPPGAFAFEGATIMEGLERIGYDTWCVGGVAFFDKRTELGSVFPGYFKHSFW
                     KPGFGCQVPDSAKNQVDFIQKKLQEADREKRIFLYVNIDAIHYPNWFYLGENASRHDT
                     IESHKAALRCADTQLGRLFDWWRETRGDAFVICCSDHGTCYGEDGCQFHGISHPAVEA
                     VPYKHFFLSQKAAGSKGER"
     gene            6855..8159
                     /locus_tag="ACZPCR_08195"
     CDS             6855..8159
                     /locus_tag="ACZPCR_08195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016279483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="STM4012 family radical SAM protein"
                     /protein_id="HIR1230892.1"
                     /translation="MRRYVQYMYSYPHKTAYRPLEGVSLEDRAGLLADRENEWYIHLP
                     FCESKCGYCNLFSVAGADPALIEAYLDRVEIQASQYREMFERQEKMPVFSSLTVGGGT
                     PLLLSPAQLQRMFSIVKRTAPMTEKPEIIVETAPNQTTEEKLALLRENGVTRVSIGVQ
                     SFLDSELLTMGRRHRAAQAEKALELMKQTGFDCVNLDLIYGVPGQTKESFLFSVAKAV
                     SFEPQELFLYPLYVRKGVSMAEGIADEEQAYSLYCEAVSFLKARGYRRDSMRRFVRSD
                     RPMSFRECGYGNTLSLGCGGRSYLGNLHACAPFAVRPSQCRKRIQEFLDTEDYLAVPY
                     GIVLSEDEEKRRYSAKHLLFGPGISLDAYRSRFGTEPEADFPFLRQWKEQGLALEEER
                     TQETGERGLILGLTEEGIGWSDALGPEFISSEVRRKMEEFQI"
     gene            8156..9709
                     /locus_tag="ACZPCR_08200"
     CDS             8156..9709
                     /locus_tag="ACZPCR_08200"
                     /inference="COORDINATES: protein motif:HMM:NF038073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STM4011 family radical SAM protein"
                     /protein_id="HIR1230893.1"
                     /translation="MTQIREIQYRGSLKSCNYACSYCPFAKRPGSRRELEKDEAALRR
                     LVLGLSERASVFKEKLGILIAPYGEALIHSYYWKEMAALSRLFFVEAVGAQTNLSFQL
                     ERCLEHYEKEGGELRKLRIWATFHPEIEQPQAFAEKCRYLSERGARFSVGAVGNPAAI
                     ADIRKLADLLPEDIYLWINRMDGLGRPCTREEKKGFLELDPWFFREFFWPKADASLCG
                     SRLFLEADGRRGMCNLSASRASKGGLISRQEEAAKEAVCRRKRCTCYLAASGRSDFPG
                     RGVFGPYPQFRIPEPVKAWFFDADGTLAEEGEAVSEETALWFRSLPGRKFLATSLPME
                     EAGKRCRRIWDCLDGGVFSSGSCVILKEKRENGRKEAVFPLQEDTEAYLKRWAACKGG
                     RCFHYRRRGSLLKAVVRFPGCESGGNAAKEQEKAAEELKQALAEAGIENVRVFAEHGR
                     IQAVNERASKDSGAELLASWIGVSLDECGAAGDSSEDASLLLKCRVSLSGQEMRDIRN
                     QLSRLLEEQ"
     gene            9849..10148
                     /gene="citD"
                     /locus_tag="ACZPCR_08205"
     CDS             9849..10148
                     /gene="citD"
                     /locus_tag="ACZPCR_08205"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_component: GO:0009346 - ATP-independent citrate lyase
                     complex [Evidence IEA];
                     GO_function: GO:0008815 - citrate (pro-3S)-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HIR1230894.1"
                     /translation="MVIEKPAVAGTLESSDAQITVEPGEGTVELTIESSVIHQFGKQI
                     RKVVLETLDRLHVTDARVTVIDKGALDCTIKARVECAVYRANGITENLPWGGDIR"
     gene            10148..11050
                     /locus_tag="ACZPCR_08210"
     CDS             10148..11050
                     /locus_tag="ACZPCR_08210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase/citrate lyase family protein"
                     /protein_id="HIR1230895.1"
                     /translation="MSHPNKKRLRRSMMFLNCQKPGLIKDPYIYGPDSIMLDLEDAVA
                     ENQKDAARYSLYHALQEIDYRGVERVVRINGLDTPHWKEDIRVCVAGGADTIRIAKTE
                     CAQDVRTVEEHVLAAEREFGRPEGSTLLMAALESCRGVLNALEICESSDRLIGVALSG
                     GDYTKDLQTVITGTGVELMGARQHMIMAARAAGVQCFDTVFTNLDDMEGFAKETEMIK
                     RMGFDGKSLVNPRQIAVVHKIFTPTEKEIIFAEKVVREIDDKKAKGIGVFTVDGKMID
                     IAFYDGAKRTLALAKASGVYEGDM"
     gene            11052..12614
                     /gene="citF"
                     /locus_tag="ACZPCR_08215"
     CDS             11052..12614
                     /gene="citF"
                     /locus_tag="ACZPCR_08215"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009346 - ATP-independent citrate lyase
                     complex [Evidence IEA];
                     GO_function: GO:0008814 - citrate CoA-transferase activity
                     [Evidence IEA];
                     GO_function: GO:0008815 - citrate (pro-3S)-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HIR1230896.1"
                     /translation="MINKVGREIPEEILKATGKKVFEGAYAYDNYEYTKAAPTVRALS
                     DPKRSKMVSSIREALEKCGIRDNMTLSFHHHFREGDYVVNMVMEEVHNMGIKGITVCA
                     SSLGKANDAIVPYIEDGTITGIQSSGVRGKIGEAISGGKLRDLAIMRSHGGRVRAIES
                     GEVHIDIAFIGAPTCDEYGNCRPNGGKSDCGVLSYAMVDAEYADKVVAVTDCLVPFPN
                     IPASISMTNVDYVCVVDAIGNPEKIATGAAKPTTDVRKLMMADYCTQFVINTPYFKDG
                     FSYQTGVGGASIASTISLGKIMEERGIQMGLGLGGITMPMCQLLEKGLIRTLVDTQDF
                     DMGAIESIKKNPNHIEISASEYANPFNKGAYVNKLDFVILAALEVDVNFNCNVVVGSN
                     GVITGAQGGHPDTAAGAKCTIVIAPLLQGRIPAVCTDVTTVTTPGETVDVVITDYGIA
                     INPKRQDLIDCMKEKNVKLPFCTIEELRDKAYAMTGTPDPVQFEDRVVGIIEGRDGTI
                     MDVVRQIKEFEF"
     gene            complement(12753..13658)
                     /locus_tag="ACZPCR_08220"
     CDS             complement(12753..13658)
                     /locus_tag="ACZPCR_08220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HIR1230897.1"
                     /translation="MNLKHAQYMMTILQEGSITAAAKKLFISQPSLSQMVKLVETNLG
                     TAVFNRTTEPLSLTPAGEKYMEAAGQILAIHANLEREIEEIRAEEHGKIKFGIPVQRG
                     MMLLPLALPRFFEAYPHVTVELFEQGSSLMEHMVLNGTVDLACMTTVARHEELTYQLL
                     ENEELVLLAARSTSLASRIPDGTPISITEAKNERFIANKPGHNVRTIQDSLFIASGIQ
                     PKILLETGSIEVGRRVCLACGAVMLFPKSCIENTEELKEKACVYPVLNSATDRHCYLC
                     FKKGLYLTKYMRDFMDFLLNAKSGL"
     gene            complement(13825..14403)
                     /locus_tag="ACZPCR_08225"
     CDS             complement(13825..14403)
                     /locus_tag="ACZPCR_08225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006428808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HIR1230898.1"
                     /translation="MNKMNSAAERRPFLTVQTMSLIGLMTALTCVLGPLAIPLPFSPV
                     PISFTNLAVYLAVYVLGMKAGAVSYLVYLLLGMAGLPVFSGFTGGFGKLAGPTGGYLI
                     GFIFMAVISGFFIDHFPGKKLFHAAGMVLGTGVCYLFGTSWLSHQLGVSFTAGLASGV
                     IPYLPGDAAKILFALVIGSRLRREIVRLSLRS"
     gene            complement(14495..15460)
                     /gene="bioB"
                     /locus_tag="ACZPCR_08230"
     CDS             complement(14495..15460)
                     /gene="bioB"
                     /locus_tag="ACZPCR_08230"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006568938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004076 - biotin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HIR1230899.1"
                     /translation="MRSGAAEHTAEEIIKGKRLTQEDDVSFLLTEDLDALRRGADAIR
                     KALCGQYAELCSIINGRSGRCPENCKFCAQSACWQTKIEEYPFLEPTAILSDCRLHEA
                     RHVRRYSVVTAGRALSGQEFEQALAAYRSMAKNCDINLCASHGLLSEADFHRLKEAGV
                     TRYHANIETSRRNFPNICTTHTFDDKLEVIRRARAAGLDVCSGGIIGMGETWEDRVDM
                     AFTLSGLKILSIPLNVLRPIPGTPFENLPPLSEEDILRTVAVFRYLNPEAQIRLAAGR
                     NSMADSGRNAFLSGANAAITGDMLTTSGNGIDADQKMLAEMGFSL"
     gene            15637..16515
                     /locus_tag="ACZPCR_08235"
     CDS             15637..16515
                     /locus_tag="ACZPCR_08235"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HIR1230900.1"
                     /translation="MLKSMTGFGRCEIATEEYKISVEMKAVNHRYLDLSIKMPKKFNY
                     FEASIRTLLKQYIQRGKVDLFITYEDYTEEKMALKYNASLAAEYMAYFEKMAEQFHID
                     NDIRVSDLARYPDVLMMEQVPEDEEHMWAILKEAVTEAASRFVETRVKEGENLKADLL
                     AKLDHMAVLVREIEERSPAIVAEYRQKLEEKVKELLSGTAIDEGRIAAEVTIFADKIC
                     TDEETVRLKSHIEATKTELLSGGSVGRKLDFIAQEMNREANTILSKANDLEVSDKAIA
                     LKTEIEKVREQIQNIE"
     gene            16580..17212
                     /gene="gmk"
                     /locus_tag="ACZPCR_08240"
     CDS             16580..17212
                     /gene="gmk"
                     /locus_tag="ACZPCR_08240"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - GMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HIR1230901.1"
                     /translation="MDNQGTLVVVSGFSGAGKGTVMKALISKYENYALSISATTRAPR
                     EGEENGREYFFKTREEFEEMIREDQLIEYAQYVENYYGTPKKYVFDNIEAGKDVLLEI
                     EIQGALKVKEKFPEAMLVFIMPPSAEELKRRLVGRGTEDAQTIQARLKRAGEEADSIQ
                     QYDYTVINDTVENCVETLHALIQSQRARVGNHREFIAQVQKDVKQLTADK"
     gene            17308..17565
                     /gene="rpoZ"
                     /locus_tag="ACZPCR_08245"
     CDS             17308..17565
                     /gene="rpoZ"
                     /locus_tag="ACZPCR_08245"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HIR1230902.1"
                     /translation="MLKPSYTDLMEVVNSGVEEGADPIIQSRYSIVIATAKRARQLIA
                     KEDPSIASASRKPLSVAIDELYSSKVKIVSEDDSSEDDIQF"
     gene            17657..18997
                     /gene="rimO"
                     /locus_tag="ACZPCR_08250"
     CDS             17657..18997
                     /gene="rimO"
                     /locus_tag="ACZPCR_08250"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008398112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008172 - S-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0018339 -
                     peptidyl-L-beta-methylthioaspartic acid biosynthetic
                     process from peptidyl-aspartic acid [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HIR1230903.1"
                     /translation="MKILCVSLGCDKNLVDTEMMLGLLNKDGYTFTDDEYEADIILIN
                     TCCFIGDAKEESVNTILEMAELKKTGQCKALIVAGCMAQRYKEEIMQEIPEVDGILGT
                     STYDEISDVIRQALSGQEHISCFHDLSVLPDVKEKRLVTTGGHYAFLKIAEGCDKRCT
                     YCIIPYLRGPYRSVPMERLLEQAEELAEQGVKELILVAQETTLYGVDLYGRKALPELL
                     RKLAAVSGIQWIRIQYCYPEEITEELIQTIKTEEKVCHYLDIPIQHASDRILKRMNRR
                     TTLAELKKNIARLREEIPDIALRTTLISGFPGETKEDHELLLDFVEEMQFERLGVFAY
                     SAEEDTPAASFPDQVPQEIKEERRDEIMELQQEIAFEKSENMEGRILEVMIEGKVADE
                     NAYVGRTYMDAPNVDGLIFVNGDEPLMSGDFCRVRVTGALEYDLIGELCDESAE"
     gene            18981..19523
                     /gene="pgsA"
                     /locus_tag="ACZPCR_08255"
     CDS             18981..19523
                     /gene="pgsA"
                     /locus_tag="ACZPCR_08255"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002595507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HIR1230904.1"
                     /translation="MNLPNKLTVLRVIMIPFFVFFLLWQGGENRTFRLIALALFIIAS
                     LTDLLDGKIARKYNLVTNFGKFMDPLADKLLVCSALICLIELGELPAWMVLIIISREF
                     IISGFRLVASDNGVVIAASYWGKFKTTFQMIAVVLLILDIPSLVLLTNLCVWIALALT
                     IISLVDYIVKNHKVLTEGSI"
     gene            19526..20770
                     /locus_tag="ACZPCR_08260"
     CDS             19526..20770
                     /locus_tag="ACZPCR_08260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HIR1230905.1"
                     /translation="MVVELVSVGTELLLGNIVNTNARYLSEKCAMLGLSVYYQTTVGD
                     NEERLAEVIKTALNRSDIVILNGGLGPTEDDLTKETCAKVMGLPLVTDQHTEERLKEY
                     YKGRKKEDLPESNWKQAVIPERAVVFDNGNGTAPGLVVEQNGKTVILVPGPPNELYPM
                     MEKQICPYLQKKNEEVILSQMVKICGFGESKVEEMILDLIDKQTNPTLATYAKQGEVH
                     LRVTARAATEEEAKKLLKPMVKEIKKRFGEAVYTTDEKETLTDVVVKLLKKHELTVTT
                     AESCTGGLLAGTLVGVPGVSEVFREGFVTYSNKAKRKLLDVSKSTLKKYGAVSAQTAK
                     EMAKGGVFATDADICVAITGLAGPDGATPEKPIGLVYIACYMNDKVHVEEFRFKGDRQ
                     KIRERSVVQALDVLRRSILEFA"
     gene            20826..21143
                     /locus_tag="ACZPCR_08265"
     CDS             20826..21143
                     /locus_tag="ACZPCR_08265"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230906.1"
                     /translation="MRFYQHLYMGEQAAGKRFQILQGLRERKIQPDIYVITLASGGNN
                     LLDIYSCLEIRRPWREAEDPLVVGIAAGYEEACLLAGQIVSQVYQETGGFAVRQYLEK
                     NAQ"
     gene            21152..22120
                     /locus_tag="ACZPCR_08270"
     CDS             21152..22120
                     /locus_tag="ACZPCR_08270"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230907.1"
                     /translation="MLHIVFFILKLILLLILAVLAVILAVFLSVLLAPVRYQGEMSLH
                     ERFSAEGKISWLFHLLACSFSWGEEGIKTDLRILWFHPFQEKQGAETEAGESALEEPA
                     EEDLVTVMEKGSEEMPEDPDVFPGPTEFSSSWKENGKEEAKEQERVEKQEAKTASPEA
                     FGEEKKRREGLFGRMKGKAEQLKKRVSRTARRVRKNILSLKQKKDSLSDLLSDEKNKK
                     TFRLLVKETKRLSKKLFPQIKGSVSFGVDDPYLMGQILTVLAFFYPYYGHSLELEAVF
                     NENVLEGDVSVKGKFSFGTFALSGLRILGDRNFRALIKRFLREGGV"
     gene            22124..22552
                     /locus_tag="ACZPCR_08275"
     CDS             22124..22552
                     /locus_tag="ACZPCR_08275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013272623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HIR1230908.1"
                     /translation="MADNQFSSTVEALFKGMDSFVTTKTVVGEAVKIDDAIILPLVDV
                     SCGMAAGAFNQPAKNNGAGGMSAKISPSAVLIIQNGVTKLVNVKHQDAVTKIIDMVPD
                     FVNRFAGGVSHTPSQEAVKAAEDMADSFQEKEKEETPKAE"
BASE COUNT         5919 a         5138 c         6521 g         5328 t
ORIGIN      
        1 aatcggcata cgtgcaggtt cgcgcttcaa ttcctttgct gcgcaaacgg ctgacaaagg
       61 tatgaaaaaa gaaaaatgcc ggagaggttt caattacaat tttggcagaa gtggtttcct
      121 ggtattatcc ggaaacagag gcactgacta tatattcaca agatagtgat acttatgagt
      181 tccagcgtaa ggctgaggcc agtttgagag aaatatttac ttcaaggacg ccagtgccgg
      241 tttcgtacaa gagcaatgat gctattcttt gccagctttt ccgtgatggg aaaataaata
      301 ttgaaaatct gggggattac aggaaggata ttcgtaagat tacttacagt aagatacagg
      361 atgaccattc tgtaatttta gtaacggaag tggttgataa tgatctgttt ttagctctag
      421 ttcaggatac atcggttcat attatttttt agtaaatctc ggaaaatttt ccagagctgc
      481 ttgattcagc taaactggaa agggagaaac aagcaggata cataataata taaacacacc
      541 ttcaagtaca ggcagggcct ttcagccctg cctgctttac tgccgttttt aatttacctc
      601 ctccagctta ttccctggta cggctaccag ggagtagttg gtgtggtaga tgacgaatcc
      661 tggggccgct ccggccacct ttttgatatt ctttttctga atatagtcga tttccacttt
      721 ttcattgtcc cggcctttgg agtagtaggc ggccagagct cctgcctcct cgaatacccg
      781 gtctggaagt tcttttccct cgctttttac aatgacgtgg gagcctggga tgcctttggc
      841 gtggaaccac cagtcatttc cagtggccag cttgaaggtc agctcttcgt tctggtaatt
      901 attctttccc acataaatat ggaagccgtc ggaggacagg tagtggaagg gtttgcttac
      961 caccttctgc tttttcatat tgggtccatg ttttttaatg aagccgtatt ctgtcagctc
     1021 catcttaatc tgggttaaat cctcctcttt taaggcgata tccagagccg cgctgatgga
     1081 ctccaaatgg tcgatttcac gctttgtctc ctcggtaagc tcggtaagcg cctcgaaagt
     1141 gcgctttagt ttattgtact tttcaaagta gcgctttgcg ttttcctggg ctgttttcgt
     1201 ctcgtccaga ggaatcctga tggtctcgtt ggtgtagtag ttgaggcagg aaagctcctt
     1261 ttcccctccg gccagttcat agccgtaggt gtttaaaagc tctccgtaga tccggaattt
     1321 atctcttttt tccgtatcct ttaactgcct taactggagg tcatattttt tgtaattccg
     1381 ctccagggcg gtctggacaa tccggcgcag gtccgaggat ttctgacgga ttctggtaat
     1441 gacattttta gaggcgtagt aggtttccag cacctggctc atggaggaga actccttcag
     1501 gcagcagtct gccggaaggg ctgtaaaggc aagggcagaa aactccaccg gttcctcgcc
     1561 tttatagaga atgcagggag agaactgtcc gcctttcacg gactccatag ccagggagaa
     1621 agtgcggctt agatgaatcc gctctgcctc tgaaagctct gctgccggaa tcgaggattc
     1681 gatgctggcc agatggcaga attcctccgc catgacaggg ctgatacctg taaaatggct
     1741 gtagagagct ttccccactg gctccggtgc ctgcgccatc actgcggcca tttcctcctc
     1801 gccagcttcc agaggattca gtttgcaggc cgtctgggga atgaagtatt ccctgcctgg
     1861 aagtacctcc cggacagagc tgacctgggc ggaaatgtgc ttaatgctgt cgatgatcat
     1921 tccttcgctg gtacagaaaa taatattgct gtgctttccc atcagctcca caatcagccg
     1981 tttccggcag agatctccca tctcatccag atgctcgatt tcaaactcca ccgcccgctc
     2041 cagacctggc tgggtgatgg aaataatttt tccgtttcca atgtgctttc tcagcagcat
     2101 acagaaattc ggcgcagtca gagggctgtt tttgtttttg tctgtcaggt aagccagcgg
     2161 aaggctgggg ttgaccgata aaagcagccg gtaattttcc ctgttgtttt ttatggtaaa
     2221 taaaagctcg tccttttccg gctgggcaat ttttgcgatt tttccgccgg cgatggtctg
     2281 gttaaattcg tgaaccaggg acgcgatgac aattccgtca aaagccatga ataaaatcct
     2341 ccttatttgc gataattaaa agcgttcctc tggcgagatt ccctgcaggc ggaggagaaa
     2401 tacagtgaga gccagcagat ccgcgcagcc tccggggctt atatttttct cgatgaagtc
     2461 ctgattcatg gacgaaaggc gtgcctgcca tccgtctgtc actgcgccgc cgtctaaaag
     2521 agcctttcgg gcctgctccc tgacgtagag ggccgcgtcc attccgcctc tgtggatcac
     2581 attggtgtcc tccacctggg ccatgaggga gaggagagtc tgaaggcagg ctctgttcca
     2641 gatatctccg gaaatctctg tttttccgcc aagggcctca agggctgagg agaaagctgc
     2701 catggaaata gaggacagag cgggaaatcc gtcggaggcc tctccccgta tgccccggca
     2761 gccgtaggcg aggtacagtt tttcgccgtg ggaaaaatgg acgtttcctg ttccggactt
     2821 cgcatctgcc tgctgtctgc gctgctccag agctgaaaaa tcttcttgaa tttccttccg
     2881 gcagagcttt ccggccagag agagaagctc agacagattc agagaaggca gattcagcct
     2941 gctctggccg aagagaaatc cggcgctggc agccagaatt cccatagaaa aaatgattcc
     3001 cttgtgggtg ttgactcctc ctgcagcgtc aaacatggct gtttctgcca gaaggccggt
     3061 ttttctgatc tgggagaaga gaagagggag atccggttct tttttgtcct catccgctgt
     3121 ctgcctggaa aaatggattc cctgttctgc catagtcctg atatagggag ccactgcccc
     3181 ggcacttttt agaaaggttt cacagcacat atcccggtgg gcaccgttgt ccaaacggtc
     3241 taccagaccg ggcttcggag tggcggacac ctcatctgtc agggattccc tggcagccag
     3301 atacaggtgg tttaaaaatg cgtcctctgc catcagctgc tgaatatggg aaaccagatc
     3361 ctccaccgtg tgctttcggc ttctggagca ggcgtgggcc ggctctccgc agagcaggca
     3421 gcggcggccg ggaagtccga tctcctctct ggaaaccttg cttttgtctg tgcggatgat
     3481 gtcaatatcg tagagccgtc cgccagccgt ctcctcctca agagaggagg taatctgctt
     3541 gagagtttcc ggcttcgagt ctgcgcagag aaacagctcc agtccagtgt gctcccgcag
     3601 ctgggtctcg aataaaactg gcacggaagc ctgcttcagg gcctgccgga cagactctga
     3661 tccccggcgg aaaaactcct ctgttcccgg aagaattttg accggtcccg ggatattcag
     3721 ggtaaagctg accaccggga cctgatacgt cccaatcagc tgttcctgga gacgggctct
     3781 ccgctctctg gcttccatca tatcttccac agaaacaggg cggcagagcc ggccggaatc
     3841 tgcgccgttt ttcagtgatt tatcagaata aaaatggttc atgtgcattc tcctgtcgat
     3901 tggattacat agctacacta ttataatgaa attttgtgag aagcacaact gttttagatg
     3961 actttatcag gcggaaatgg tatactgaca ctatctttaa ggaaaattgg agaagattta
     4021 gagaaaagag aggagaagcc tatggcgaaa agcaagaagt atttttacga ctacgatatg
     4081 gccgaggagg gaaagggacc gaggaccatg attccggaaa ttctcgcgga cagcgaattt
     4141 ccttctctga cagagctggt gattggcgac tggggaacct cctgggaaga gggctgccag
     4201 cagatgatcg atgatattgt ggcgaacaaa gaaaagtttt cccacattac gtcgctgttt
     4261 atcggagata tggattttga agaatgcgag gtttcctgga ttattcaggg cgattacagc
     4321 aggatctatg aggccatgcc gcagttaaaa tccctgacga ttaaaggaag cacagaactt
     4381 cggcttgggg ctatttctca cgagggactg gaggaactga cgattatctg cggaggcctt
     4441 tcagaggacg tatttaaaag cattgagcag gcccatcttc caaacctgaa aaagcttctg
     4501 ctgtacattg gggtggagga ttacggcttt gacggcagca tcgacactat caggagcctt
     4561 ctggctaatt ctgacttccc cagactttct tacctgggcc tgacagacag cgagcttcag
     4621 aatgaggtgg cagccgctgt gctggagagc aaatatatcg gacagataga gactctggat
     4681 ttatcggagg gaactctgaa cgataaggga ggcgaagttc ttctggcagg gctgcctggg
     4741 tatcccaacg ttaaaaagct ggatcttcat taccactata tgacagagga gatggaggga
     4801 aaattgaagg cgcttcctct ggaactggac gtttcagagc ggaaccttcc agacgagtat
     4861 aatggggagc tttggatgta ccccatgctg acagagtgag acaggcacat cttctgggag
     4921 tttccggcca taagagaacc aggtactttc agaaggcggc agcggaagcg gggctttttt
     4981 tcggcttttc tgactggaag ctctttttgg agcatccctc ccttccggat caggatctgt
     5041 ttgtcaagct agatccgttt cctgccgcag gtgttttttt gcaggatctg gagcagaacg
     5101 tccgagcgta ccggacagcg ctggaacgcc tggaggagag tgagaagctc agaaggcaaa
     5161 gcgggcttca gacccagtgg ctgaacacgc cgggcggcat cctgtcggct ctcaataaga
     5221 gggagtgcca gagccgcctg cttcaggctg gcatccctgt gacgggagaa gggctgcaga
     5281 tacaggggaa gaacggtttt tcagggggag aagagctgct ttcctggatg gcagagcaga
     5341 gggagagcca gattttttta aagccagtct ggggatccgg tgcggcggga gtctgcgcgc
     5401 tcagatttca tcctgagaaa ggcacaggcg ccctttatac ctgcgcggct tctgcggagg
     5461 ataatctgag aggacagagt ttgatcaaca cgaaaaagct gcgtgttttg agggacagga
     5521 aagaaatcgc agccttttta gaccagcttc tttccatgga ctgtctggca gagcgctggt
     5581 accccaaggc ctcctttcag agctacagct acgatctgag ggcagtctgg cagttcggac
     5641 agttggattt tctgctggcc cgcctgtcaa aggggcctct caccaatctg cacctgaata
     5701 accatcccct gcctgccagg gagctgggac ttcctctttc tgtgcgcgag gagctggaag
     5761 aactctgcag acagacttcg cttgtctttc cgggccttat gagcttcggc gcggatattc
     5821 tgctggaaag gggcagtctg aggccgagaa tcattgagat caacggacag ggagatctgc
     5881 tttatcagga tatttaccag gaaaacagga tttacagacg ccaggcagag gtgatgaaag
     5941 cctggatgga agaacagggg gacaaatttg aaaccagacg taccatttga gcagttcggc
     6001 gcgaaagaag cgccgtcctt tgatatgaac gaggtggcag gaaagaagga tatccttttt
     6061 atctgcctgg atactctgcg ctacgacgcg gcgaaggaag aggaagaaaa gggcaatact
     6121 cctgtgctga atcagtatgg accgtggcag aagtgccagg cgccggggaa ttttacatat
     6181 ccgtcccacc acgccatgtt tgcaggtttt ctgccctgcc catgggaggc caggtccatt
     6241 gcagacagaa gcatgctgtt ttttcccaag aatatcggta tgggaagaat gacgccgccc
     6301 ggagcctttg cttttgaggg agccacgatt atggaggggc tggagcggat cggatacgat
     6361 acctggtgcg taggcggggt agcgtttttt gataagcgca cagagcttgg cagcgtgttt
     6421 ccaggatact ttaaacatag tttctggaag cctggctttg gctgccaggt tccggacagc
     6481 gcgaaaaacc aggtggactt cattcagaag aagcttcagg aggcagacag ggagaagagg
     6541 atttttctct atgtgaatat agatgccatc cactatccca actggtttta tctgggggag
     6601 aacgcttcca ggcacgacac catagagagc cataaggccg ccctgcgctg cgcagatacc
     6661 cagctgggcc gtctgttcga ctggtggaga gagacgagag gagacgcttt tgtcatatgc
     6721 tgttctgacc acggcacctg ctatggagag gacggctgcc agtttcacgg catcagccat
     6781 ccggcagtgg aagcagtgcc gtacaagcat tttttccttt cgcagaaggc ggcgggaagc
     6841 aaaggagaga ggtaatgcgc agatacgttc aatatatgta cagctatccc cataaaacgg
     6901 cataccggcc gttagaggga gtgagtctgg aggacagggc cggtctgctg gcggataggg
     6961 agaacgagtg gtatatccat cttccgttct gcgagagcaa atgcggatac tgcaatctgt
     7021 tttctgtggc aggcgctgac ccggcgctga tagaagctta tctggaccgg gtggagatcc
     7081 aggcttctca gtaccgggag atgtttgagc gtcaggaaaa aatgccggtt ttttccagtc
     7141 tgactgtggg aggaggaacg ccccttctcc tctctccggc ccagctgcag cggatgtttt
     7201 ccattgtgaa aaggacggcg cccatgacag agaagccgga aatcattgtg gagacggcgc
     7261 ccaaccagac gacagaggaa aaacttgccc ttttaaggga aaacggcgtc acaagagtga
     7321 gcataggcgt ccagagtttt ctggacagcg aacttttgac aatgggaaga cgccacaggg
     7381 cagctcaggc cgaaaaagcg ctggagctga tgaaacagac aggttttgac tgcgtgaatc
     7441 tggatctgat ttacggagtt ccaggccaga cgaaggagag ctttctcttc tctgtggcaa
     7501 aggctgtttc gtttgagccc caggagctgt ttctgtaccc tctgtatgtg cggaagggag
     7561 tttccatggc agagggaatt gcagacgagg aacaggctta cagtctctac tgtgaggcag
     7621 tttcttttct gaaggccaga ggctacagaa gagattccat gcgccgcttt gtgcggtcag
     7681 acaggccgat gtctttccgg gagtgcggct acggaaatac gctgtctctg ggatgcggcg
     7741 gaagaagcta tctgggaaat cttcacgcct gcgcgccctt tgcagtgcgc cccagccagt
     7801 gcagaaagcg gattcaggaa tttctggata cagaggatta tctggcggtt ccctatggga
     7861 ttgtgctttc agaggacgag gaaaagaggc gttacagcgc aaaacatctg ctgtttggac
     7921 cggggatttc cctggacgcc taccgaagca gatttggaac ggagccagaa gcagattttc
     7981 cttttttgag acaatggaaa gagcagggcc ttgcgttaga ggaggagagg acacaggaga
     8041 cgggagaacg gggcctgatt cttgggctga cagaggaggg aatcgggtgg tcggacgccc
     8101 tagggcctga atttatttcc tctgaggtaa ggcggaaaat ggaggaattt cagatatgac
     8161 gcagattcgg gaaattcagt acagaggaag cttaaaaagc tgtaattacg cctgctccta
     8221 ctgtcccttt gccaagcggc ccggcagcag gcgggagctt gagaaggacg aggccgctct
     8281 gcgccgtctg gttctgggac tttcagaacg cgcttctgtt tttaaggaaa aactgggcat
     8341 cttgatagcg ccctacggcg aggccctgat ccacagctat tactggaagg aaatggcggc
     8401 tctcagccgc ctttttttcg tggaggcggt gggagcgcag acgaatctca gctttcagct
     8461 ggaacgctgc ttggaacatt atgaaaaaga agggggagag ctcagaaagc tcagaatctg
     8521 ggccactttt cacccagaga tagagcagcc gcaggcattt gcagaaaaat gcagatacct
     8581 ctcagagcgg ggagccagat tttccgtggg cgcagtggga aatcctgcgg ccattgcgga
     8641 tatcaggaag ctggcggatt tgctgccaga ggacatttat ctgtggatca accggatgga
     8701 tgggctggga cgtccctgta cgcgggagga aaagaaaggg tttctggagc tggatccctg
     8761 gtttttccgg gaatttttct ggccgaaggc agacgcttct ctctgcggca gccgtctttt
     8821 cctggaggca gacggaagga gaggaatgtg caatctttcc gcatcccggg catcaaaggg
     8881 aggactgata tccagacagg aggaggctgc caaagaggcc gtctgccgaa gaaagcggtg
     8941 tacctgctac ctggcggctt ccgggcgcag cgattttccg ggaagaggcg tgtttggccc
     9001 ctatccccag tttcgtattc cagaaccagt gaaggcctgg tttttcgacg cagacggtac
     9061 gctggcagag gaaggagaag cggtgagtga ggagacggct ctgtggtttc gcagccttcc
     9121 tggaaggaaa tttttagcta cctcccttcc gatggaagag gctggaaaac gctgccggag
     9181 aatctgggac tgcctggacg gaggcgtgtt cagcagcggt tcctgcgtca tattaaagga
     9241 aaagagagag aatggcagaa aagaggccgt tttcccgctt caggaagaca cagaagctta
     9301 tttgaagcgc tgggctgcct gtaagggagg aagatgtttc cattacagga gaaggggcag
     9361 cctgctgaag gcggtggtcc ggtttccagg ctgtgaaagc ggcggaaatg ctgcaaagga
     9421 gcaggagaag gcggcagaag agcttaagca ggccttagct gaagcaggga tcgaaaacgt
     9481 ccgggtcttc gcagagcacg gcagaatcca ggcggtaaac gagagagctt ccaaggattc
     9541 gggggctgaa cttttagcat cctggatcgg cgtttctctg gatgaatgcg gggcggcagg
     9601 agattcttcg gaggatgcgt cccttctttt aaagtgcaga gtctccctgt cgggacagga
     9661 gatgagggat attaggaacc agcttagccg tctgctggag gaacaatagg ctttctccta
     9721 tatttcctat aattctttaa gtatttgccc tttctgtctg ccggtgatac gatacaggta
     9781 gtaaagaaac taccaagata ataggaatgg aagatgtttc catgaaagat cataaggagg
     9841 agaagggtat ggttattgaa aaaccggcag tagcaggaac tttggaatcc agcgacgctc
     9901 agattacggt ggagccgggc gagggaacgg tggagcttac cattgagagc agcgtaatcc
     9961 accagtttgg aaaacagatc agaaaggtcg tgctggagac tcttgaccgt ctgcatgtga
    10021 cagacgccag agtgacagtc attgacaagg gagcgctgga ctgcactatc aaggccagag
    10081 tagagtgcgc cgtgtatcgg gccaacggca tcacagaaaa tcttccgtgg ggaggtgaca
    10141 ttcggtaatg agccatccaa ataaaaagag attaagacgt tccatgatgt ttttaaactg
    10201 ccagaaacca ggacttatca aggatccgta tatctatggt cctgattcca ttatgctgga
    10261 tctggaggac gcggtagcgg agaatcagaa ggatgcggcc agatattctc tctaccatgc
    10321 ccttcaggag attgattaca gaggcgtgga gcgggtagtc cgcattaacg gcctggatac
    10381 tcctcactgg aaagaggata tccgtgtctg tgtggcaggc ggagccgaca ccatccgtat
    10441 cgccaagaca gagtgcgccc aggacgtaag gactgtggag gagcatgtgc tggcagcaga
    10501 gcgggaattt ggccgtccag agggaagcac tcttctgatg gctgccctgg agtcctgccg
    10561 cggcgtgtta aacgctctgg aaatctgcga gtcatctgac cgcctgattg gcgtggcctt
    10621 atccggcggc gattacacaa aggatctgca gacggtcatt acaggaacag gcgtggagct
    10681 gatgggagcc agacagcaca tgatcatggc tgccagagcg gcgggcgttc agtgctttga
    10741 cacggtattt accaatctgg acgacatgga aggctttgcg aaggagacag agatgataaa
    10801 gcgaatgggc tttgacggaa aatctcttgt caatccgaga cagatcgcag tggtacacaa
    10861 gattttcacc ccgacggaga aggagattat ctttgccgag aaggtagtgc gggaaatcga
    10921 cgacaaaaag gcaaagggaa tcggagtatt taccgttgac ggaaaaatga tcgatatcgc
    10981 cttctatgac ggagctaaga gaactctggc cctggcgaag gcgtccggcg tatatgaggg
    11041 ggatatgtaa gatgataaat aaagtaggac gagagattcc ggaggagatt ttaaaggcca
    11101 ccgggaaaaa ggtatttgaa ggcgcgtacg catacgataa ttacgaatat acaaaagcgg
    11161 ctcctactgt ccgggcctta tcggatccaa agcgctccaa gatggtttct tccatccgcg
    11221 aagccctgga aaagtgcgga atccgcgaca atatgactct ttccttccac catcacttcc
    11281 gcgagggaga ttatgtggta aatatggtga tggaagaggt tcacaatatg ggaatcaagg
    11341 gcatcaccgt ctgcgccagc tcgttaggaa aggcaaacga cgccattgta ccttacattg
    11401 aagacggaac catcacaggc atccagtcct ccggcgtgag aggaaagatt ggagaggcta
    11461 tttctggcgg aaagctgaga gatctggcga ttatgcgttc ccacggcggc cgtgtgagag
    11521 ccatcgagtc aggcgaggtt cacattgata tcgccttcat cggagcgccc acctgcgatg
    11581 agtacggaaa ctgccgtcca aacggcggaa agagcgactg cggcgtattg tcctacgcca
    11641 tggtagacgc ggagtatgca gacaaggtcg tggcggttac agactgcctg gtgccgtttc
    11701 caaacattcc ggccagcatt tccatgacca acgtggacta tgtgtgcgtg gtagacgcca
    11761 tcggaaatcc ggagaaaatc gccacaggag cggcaaagcc taccacagac gtgagaaagc
    11821 tgatgatggc cgattactgt acccagtttg taattaacac gccttatttt aaggatggat
    11881 tttcctacca gacaggcgta ggcggcgcgt ccatcgcctc cacaatttcc ctgggaaaga
    11941 ttatggagga gcggggcatc cagatggggc tggggctcgg cggaattacg atgcctatgt
    12001 gccagctgct ggagaagggc ttaatcagaa ctctggtaga tacgcaggat ttcgatatgg
    12061 gagccatcga gtcgattaag aaaaatccaa accacattga gatttccgcc tccgaatatg
    12121 cgaacccctt caacaagggc gcttatgtca ataagctgga tttcgtgatc ctggcggctc
    12181 ttgaggtgga cgtaaacttt aactgcaacg tggtggtcgg atctaacggc gtgattacag
    12241 gcgctcaggg agggcatccc gacacagccg caggcgccaa gtgtacgatt gtgattgctc
    12301 cgcttctgca gggcaggatt ccggctgtct gcacagacgt aacaactgtc accacgcctg
    12361 gagagaccgt agacgtagtc atcacagatt acggcattgc catcaatccg aaacgccagg
    12421 atctcattga ctgcatgaag gaaaagaacg taaagcttcc gttctgcacc attgaggagc
    12481 tgagagacaa ggcgtacgcg atgacaggaa ccccggatcc agttcagttt gaggacaggg
    12541 ttgtgggaat tatcgaagga cgcgacggaa ccatcatgga tgtggtaagg cagatcaagg
    12601 aatttgagtt ttaactgcag cagaaaataa atgagacatc cattctaaac aactatcttc
    12661 attatatcgc atcagccgtc tgccctgctt tttgcggagt ccaggcggct gatacagatc
    12721 tgttatgaga acggcagggg cgctgggata ctctacagtc cgcttttggc gtttaaaaga
    12781 aaatccataa aatcacgcat atattttgtc aggtataggc cttttttgaa gcaaagatag
    12841 cagtggcggt ctgtggcaga attcagcaca gggtagacgc aggccttttc cttcagctct
    12901 tctgtatttt caatgcagct tttgggaaag agcataacgg ctccgcaggc caggcagacg
    12961 cggcgtccca cttcgatgct tcccgtttcc agaaggatct tcggctggat tccgcttgca
    13021 ataaaaaggc tgtcctggat ggtgcggacg ttgtggcccg gcttgttggc aataaaacgc
    13081 tcatttttcg cctccgtaat agaaatgggg gttccgtctg ggattctgga agccagactg
    13141 gtagagcggg cggccagaag aaccagctct tcattttcca gaagctgata agtcagctct
    13201 tcatggcggg ctaccgtagt catgcaggcc agatccaccg ttccgtttaa caccatatgt
    13261 tccattaggc tggaaccctg ttcaaaaagc tccactgtca catgggggta ggcttcaaaa
    13321 aagcggggca gagccagagg aagcagcatc atgcctctct gaacgggaat tccaaatttg
    13381 atttttccgt gttcctccgc ccgtatttcc tcaatttccc gctctaaatt agcgtggatg
    13441 gccagaatct gtccagccgc ctccatgtac ttttcgccgg ccggagtcag agacaatggc
    13501 tcagttgttc gattaaaaac cgccgttccc agatttgtct ccaccagctt taccatctgg
    13561 ctcagagagg gctgggagat aaaaagcttc ttggctgccg ctgtgatgct tccctcctgc
    13621 aggatcgtca tcatatactg cgcgtgtttc agattcaaaa aatgcctcct tctgccgcct
    13681 gcctgccagg atgcagaagg aggcgtttat ttctgcctct atcataccag ataattgaag
    13741 taaaatccag cgggacgatt cgctgtgctt tctgtccggt ttgcggtctg ctgccgccag
    13801 agcggacgat tccgcctgtt tttatcagct tcgtagagac aggcggacga tttcccggcg
    13861 cagcctggag ccgatgacaa gggcgaacaa aatttttgcc gcgtctccgg gaaggtaggg
    13921 gatgacaccg gaggccagac cggctgtaaa ggaaactccc agctggtggg acagccagct
    13981 ggttccgaac aggtagcata cacctgtgcc aagtaccatg ccggcagcat gaaacagctt
    14041 tttgcctgga aaatggtcaa taaaaaatcc ggagatgact gccataaaaa taaacccgat
    14101 taagtatcct ccagtagggc cggccagctt tccaaaccct cctgtaaagc cggaaaaaac
    14161 agggagtccg gccattccca agagaagata gaccagatag ctgacagcgc cggccttcat
    14221 tcccagaaca tagacagcca ggtagacagc cagattcgtg aaagaaatgg gaacagggct
    14281 gaagggcaga gggattgcca aaggccccag cacacaggtc agggcagtca tcagcccgat
    14341 taaactcata gtctgcacag taagaaacgg tctgcgttca gcagcagaat tcattttatt
    14401 catagtaaac tcctgtcata tcgttattta tcaagaaaca taaacgtttg tgtgactttc
    14461 agtggaacaa aaaaagttta tgtttcttga ttttttaaag ggaaaatccc atctcagcca
    14521 gcatcttctg atctgcatca attccgtttc ccgatgtggt gagcatatct cctgtgatag
    14581 ccgcgttggc gccggagaga aaggcgttcc ggccgctgtc cgccatagaa tttctgcctg
    14641 ccgccagccg gatctgggct tctggattca ggtaacggaa gacagcgacc gttcttaaaa
    14701 tatcctcctc tgacagaggg ggaagatttt caaacggtgt gcctggaata gggcgcagca
    14761 catttaaggg gatggacaaa atcttcagcc cgctgagagt gaaagccata tcgacgcggt
    14821 cttcccaggt ttctcccatt ccgataatgc cgcctgaaca gacgtcgagg cctgctgccc
    14881 tggcccgccg gatcacctcc agcttgtcgt caaaggtgtg ggtggtacag atattcggga
    14941 aatttctccg ggaagtttcg atattcgcat ggtatctggt aacgccggct tccttcaggc
    15001 gatgaaaatc tgcctcagac agcagcccgt gggacgcgca cagattgatg tcacagtttt
    15061 ttgccataga gcggtaggcg gcgagagcct gctcaaactc ctgcccgctt aaagcccgtc
    15121 ctgcagtaac gacggaatag cgtctcacgt gtctggcctc atgaagacgg cagtcagaga
    15181 gtatagccgt tggttctaaa aaaggatact cctcgatctt ggtctgccag caggcggact
    15241 gggcacagaa tttacagttt tccggacagc gcccgctgcg cccgttgata atggagcaga
    15301 gctctgcata ctggccgcag agagcttttc gtatggcgtc tgctccgcgc cgcaaagcgt
    15361 ctaaatcctc tgtcagcagg aaagagacat cgtcctcctg cgttaaccgt ttccctttta
    15421 taatttcttc agctgtgtgt tctgcagcgc ctgatctcat ggcagcctct cctttgcaag
    15481 tgtgatggct gtattataaa cctgtgtgcg gagaattgtc aaccaaaaat aaaataaagg
    15541 tttacagttt actgtccgca tccttgattt tcagttgact tgatttttcc tatggcttat
    15601 aataataact atctatggac aaaggaaggt gcagccatgt taaaaagtat gacaggcttc
    15661 ggaaggtgcg agattgctac agaggaatat aagatatctg tggagatgaa agcggtcaac
    15721 caccgctatc tggatctgag cattaagatg cctaagaagt ttaattattt tgaagcctcg
    15781 atccgaaccc tgctgaagca gtatattcag aggggaaagg tcgatctgtt tattacatat
    15841 gaggattaca cagaggagaa gatggccctt aagtacaacg cttctctggc agcagaatat
    15901 atggcctact ttgagaagat ggcggagcag tttcacattg acaatgatat cagagtgtcc
    15961 gatctggcca gatatccgga cgtgctgatg atggagcagg ttccggagga cgaggagcat
    16021 atgtgggcca tcctgaaaga ggcggtcaca gaggcggcgt cccgctttgt ggagaccaga
    16081 gtgaaagagg gagagaattt aaaggcagat ctcctggcga agttagatca tatggcagtt
    16141 ctggtcaggg aaatcgagga gcgctctccg gctattgtgg cggagtacag acagaagctg
    16201 gaggagaagg taaaggaact cctttccgga acggccattg acgaaggccg gattgccgcg
    16261 gaggtgacga tttttgcaga taaaatctgc acggatgagg agactgtgcg cttaaagagc
    16321 cacattgagg ccaccaagac agagcttctc tccggcggca gcgtgggaag aaagctggat
    16381 ttcattgccc aggagatgaa ccgggaggcc aatacgattc tctccaaggc caacgatctg
    16441 gaggtttccg ataaggctat cgctctgaaa acagagatcg agaaggtgag agagcagatt
    16501 cagaatatcg agtagaatgc agcctgattt gactgcccac tgaattttat atgatataac
    16561 agagacagga ggatggaaaa tggacaatca gggaacctta gtcgttgtct ccggtttttc
    16621 aggagccggg aagggaacgg taatgaaggc gcttatctca aagtacgaga attacgcgct
    16681 gtctatttcc gccacaacca gagctcccag agagggagag gagaacggaa gagagtattt
    16741 ttttaagacc agggaagagt ttgaggagat gatccgtgag gatcagctga tagagtacgc
    16801 ccagtacgtg gagaactact acggaactcc taagaaatat gtgtttgaca acatcgaggc
    16861 gggaaaggac gttctgctgg agatagaaat ccagggagcc ttaaaggtaa aggagaagtt
    16921 tcccgaggcg atgctggtgt ttatcatgcc ccccagcgca gaagaactga agagaagact
    16981 ggtaggccgg ggaacagagg atgcgcagac gattcaggcg cgtcttaagc gggccggaga
    17041 agaggcggac tccattcagc agtatgacta cacagtgatc aacgacacag ttgaaaactg
    17101 cgtggagact ctgcacgccc tgatccagag ccagagagcc agagtaggaa accacagaga
    17161 atttatcgcc caggtccaga aggacgtaaa gcagctgaca gctgacaaat aagcggttaa
    17221 aagcaaaacc atggctcctc cattgataaa tgggctggac catggtaaaa taatagaata
    17281 ccagaaaaag gagatatgat cattatgatg ttaaagccat cttatacaga cttgatggaa
    17341 gtagtaaaca gcggcgtgga ggaaggcgca gatccgatta ttcagagccg ctattctatc
    17401 gtaatcgcca cagccaagcg cgccagacag ctgattgcca aggaggatcc gtctatcgct
    17461 tccgccagca gaaagccgct ttctgttgcc attgacgaac tctacagttc caaggtgaag
    17521 attgtcagcg aggatgacag ctccgaggac gacatccagt tttaaggaaa cgggccgtct
    17581 catggcttca tgccgtgaga tggcattttt gctataggaa gagaacatat aaaaataata
    17641 agtcaggaga tgaactatga agatactttg tgtttccctc ggctgcgata agaacctggt
    17701 agacacagaa atgatgttag gccttctgaa taaggacggc tacacgttta cagacgatga
    17761 atatgaggcg gatattatcc tgattaatac ctgctgcttc attggagacg ccaaggagga
    17821 aagtgtgaac acaatccttg agatggcgga gcttaagaaa acaggacagt gcaaggcgct
    17881 gatcgtagcc ggctgtatgg ctcagcgcta taaggaagag attatgcagg agattccgga
    17941 ggtggatgga atcctgggaa cttctaccta cgatgagatt tccgatgtga tccgccaggc
    18001 tctttccgga caggagcaca tttcctgttt ccatgatctg tctgtgctgc cggatgtgaa
    18061 ggagaagcgt ctggtgacca caggaggcca ctatgctttc ttaaagattg cggagggctg
    18121 cgacaagcgg tgcacctact gcattatccc ttatctgaga ggaccttaca gaagcgttcc
    18181 catggagcgg ctgctggagc aggcagagga gctggcagag cagggagtga aggagctgat
    18241 cctggtagcg caggagacga ctctttacgg agtggattta tatggaagaa aagcgcttcc
    18301 ggagcttctt aggaagctgg ccgccgtctc aggaatccag tggatccgaa ttcagtactg
    18361 ttatccggaa gagatcacag aagagctgat tcagaccatt aagacagagg agaaggtctg
    18421 ccactacctg gatatcccta tccagcacgc cagtgacaga attttaaagc ggatgaacag
    18481 gagaactacc ttggcggagc tgaagaaaaa cattgcccgc ctgagggagg agattccgga
    18541 tattgctctg agaaccaccc tgatttccgg tttcccggga gagacgaagg aggatcacga
    18601 actgctgtta gattttgtgg aggagatgca gtttgagcgt ctgggcgtgt tcgcctactc
    18661 agcggaggag gatactccgg cggcttcctt cccggatcag gttccccagg aaatcaagga
    18721 ggagcgccgt gacgagatta tggagctgca gcaggagatt gcctttgaga aatcagagaa
    18781 tatggaggga cgtattctgg aggtgatgat cgagggcaag gtagcagacg agaacgctta
    18841 tgtgggaaga acctacatgg acgcgcccaa tgtggatgga ctgatttttg taaacggtga
    18901 cgagcccctg atgtccggcg atttctgcag agtcagggta acgggagctc tggagtatga
    18961 tttgatagga gagttgtgcg atgaatctgc cgaataaact tacagtactg cgtgtgatta
    19021 tgattccgtt tttcgtattt ttcctgctct ggcagggagg agagaacaga accttccgcc
    19081 tgattgccct ggcgctgttt atcatagcca gcctgacgga cctgttagac ggaaagattg
    19141 ccagaaaata taatctggtg actaactttg gaaaatttat ggatcctttg gctgacaagc
    19201 tcttagtatg ttctgcgctg atctgcctga ttgagctggg agagcttccg gcatggatgg
    19261 tattaattat tatcagccgt gagtttatta tcagcggttt ccgtctggtg gcttctgata
    19321 atggcgtggt aattgcggcc agctactggg gaaaatttaa gacaaccttc cagatgatcg
    19381 cggtagtgct tttaattctc gatattccga gccttgtgct tttgacaaac ctctgcgtct
    19441 ggatcgctct ggcgctgacc atcatttcac tggttgatta cattgtgaag aaccataagg
    19501 ttctgacaga agggagcatc taaacatggt tgttgaactg gtatctgtgg gaacggagct
    19561 gctgctggga aatattgtaa ataccaacgc taggtatctg tctgaaaaat gcgctatgct
    19621 ggggctgagc gtctactacc agactacggt aggcgacaat gaggagcgtc tggccgaagt
    19681 gattaagacc gctctgaacc gctctgatat tgtgatctta aacggaggtc tgggacctac
    19741 ggaggacgat ttgaccaaag agacctgcgc taaggtgatg ggacttcctc ttgtaacaga
    19801 tcagcataca gaagaacgtt tgaaggaata ttataaagga agaaaaaaag aggatctgcc
    19861 ggagagcaac tggaagcagg cggtaattcc agagagagct gttgtatttg acaatggaaa
    19921 cggcacagcc ccaggtctgg tggtagaaca gaacgggaag acggtgattc tcgtcccagg
    19981 accgccgaac gagctgtatc ccatgatgga gaagcagatt tgcccctatc ttcagaagaa
    20041 aaatgaagaa gtgattctgt cccagatggt aaaaatctgc ggctttgggg agagcaaggt
    20101 ggaggagatg attttagatc tcattgataa gcagacgaat cctacccttg ccacctatgc
    20161 caaacaggga gaggtccacc tccgggtaac tgccagggcc gccacagagg aggaagccaa
    20221 aaaactctta aaaccgatgg tcaaggagat caagaaacgg ttcggcgagg ctgtgtacac
    20281 cacagatgag aaggaaacgc tgacagatgt ggtagtgaag cttttaaaga agcatgagct
    20341 gacggtgact acggcagagt cctgcactgg cggccttctg gcaggcactc tggtaggcgt
    20401 tccgggcgtg tcggaggtat tcagagaggg ctttgtcacc tattccaata aggcgaaacg
    20461 gaagctgctg gatgtgagca agagcactct gaaaaaatac ggagcagtca gcgcccagac
    20521 ggctaaggag atggccaagg gaggcgtgtt tgctacagac gcagatatct gtgtggctat
    20581 tacagggctg gcaggtcccg acggggcgac gccggagaag cccataggtc tggtctacat
    20641 tgcctgctat atgaacgata aggttcatgt tgaggaattc cgttttaagg gagacagaca
    20701 gaaaatcagg gagcgctctg ttgttcaggc tctcgatgtg ctgagaagat cgattctgga
    20761 gttcgcataa aagctttgcc aggacaaaag cggcactgcg ccaaaagagg ctttgggagg
    20821 aacgtatgag gttttaccag catttataca tgggagaaca ggcggccggg aaacggtttc
    20881 agatcctcca gggcctgcgg gaacgaaaga ttcagccgga tatctatgtt ataactttgg
    20941 cctcaggggg caataatctt cttgatatat acagctgcct ggagatcaga aggccctgga
    21001 gggaagcgga ggatcccctt gttgtaggaa ttgccgcagg ctatgaggag gcctgcctcc
    21061 tggcaggaca gatcgtcagc caggtttacc aggagaccgg aggctttgcg gtaaggcagt
    21121 atctggaaaa aaacgcgcag taggtgggaa gatgctccat attgtatttt ttattctgaa
    21181 actaattctg cttcttatat tggcagtgct ggcggtgatt ctggcagttt ttttatccgt
    21241 gcttctggcg ccggtccggt atcaggggga aatgtccctg cacgagagat tttcggcaga
    21301 gggaaagatt tcctggctgt ttcatctgct tgcctgctct ttttcctggg gggaagaggg
    21361 aattaagaca gatctccgca ttctgtggtt ccaccccttt caggaaaaac agggcgcaga
    21421 gacagaggcg ggcgaaagtg ccctggaaga accggcagag gaggacctgg tgacggttat
    21481 ggaaaaggga tcggaggaaa tgccggagga tccagatgta tttccaggac cgacggagtt
    21541 ttcttcttcc tggaaggaga acgggaagga ggaagccaag gaacaggaga gagtggaaaa
    21601 gcaggaggcg aaaacagcca gccccgaagc cttcggggaa gagaaaaaac gcagagaagg
    21661 gctttttggc cggatgaaag ggaaggcgga acagctcaaa aaacgggttt cccggacagc
    21721 tcggcgcgtc agaaagaata ttctgagtct gaagcagaaa aaggacagtt tgtctgacct
    21781 gctgtcagat gaaaaaaata agaaaacctt ccgtctgttg gtgaaagaaa caaaaaggct
    21841 ttccaaaaag ctgttccctc agataaaagg ctctgtttca tttggagtgg acgatccgta
    21901 tctgatggga cagattttga cggttctggc gtttttttat ccgtactacg gacacagcct
    21961 tgagctggag gcagttttca atgaaaatgt gctggaggga gatgtttctg tgaaggggaa
    22021 gttttctttc ggaaccttcg ccctgtccgg actccgaatt ttgggcgaca ggaacttcag
    22081 agctctgata aaacggtttt tgagagaagg aggagtatag aggatggcag ataatcagtt
    22141 ttcatccacc gtggaggcgc tgtttaaggg tatggacagc ttcgttacca cgaaaacagt
    22201 agtaggcgag gcagtgaaaa tcgacgacgc gattattctt cctctggtgg acgtgtcctg
    22261 cggcatggcg gcaggcgctt ttaaccagcc ggcaaaaaac aacggagccg gaggcatgag
    22321 cgcaaagatc agtcccagcg ccgtgcttat tattcagaac ggagtgacaa agttagtcaa
    22381 tgtgaagcat caggacgctg tgacgaaaat tatcgatatg gttcctgact ttgtaaaccg
    22441 ctttgccggc ggcgtcagcc acactccctc ccaggaagcg gtaaaagcag cggaggatat
    22501 ggcagacagc ttccaggaga aagagaagga agaaacgcca aaggcagagt aaaagcatca
    22561 aaatcgacag cagaaagcag gcagaaatac gatagcagga gttcagactc ctgttatttt
    22621 tttgtcataa aaacgagaaa aataacaatt cttgttgtga aaactagcag cctttttctg
    22681 cagttgatca gcagaatttt aaagggaagg aaaaattaga agaaaaaagt cagaaaaaag
    22741 aagaagaaaa attgaaaaga acagaggaaa ttatatggga tttggagaaa aacttgcttg
    22801 ttcaagcaga taacattcca aaaatttgga aaatacaata aaatacagaa aatgacagag
    22861 gttttacgga aatttaacag aacaaatgta ctgtcaaacg gaaaga
//
LOCUS       DBMDUW010000039        22220 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1507_length_22220_cov_3.870790, whole genome shotgun sequence.
ACCESSION   DBMDUW010000039 DBMDUW010000000
VERSION     DBMDUW010000039.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 22220)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 22220)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22220
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1507_length_22220_cov_3.870790"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(18..1448)
                     /locus_tag="ACZPCR_08280"
     CDS             complement(18..1448)
                     /locus_tag="ACZPCR_08280"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HIR1230909.1"
                     /translation="MEELLRMEGISKSFSGVRVLNRVELTVKHGEVHALLGENGAGKS
                     TLIKILGGAYTKDEGTIYIEGNKTEITSVESARSHGIRVIHQELMLIPYMTVAENIFL
                     GQEPKTKRGTVDTAKMNRDTAAFLKEMELDIQPDEQVGRLNIAKQQMVEIARAISFGA
                     KIIVMDEPTSSLTDTEVEVLFKAIRRLKEKGVGIIYISHRMSELDEIADRITVMRDGE
                     YIATVVTKDTTHDHLVSLMVGRSLGDLYDKHNHSGEETVLSVHHLAAGKEVRDVSFEL
                     KKGEVLGFSGLVGSGRSETMEALFGLRRKDSGEILVNGKKVQIKNVKDAMNCGLGLVP
                     EDRKKEGIFAVQGIRFNTTIEVLDQFLKGGAYSREKEISLIRTYVDQVMETKYAGIEQ
                     PIGRLSGGNQQKVIISRWLLATEKILILDEPTRGIDVKTKADIYHLIDRLTAEGLSVI
                     FISSEMPELITHCFLHPGCDWPGPFS"
     gene            complement(1489..2523)
                     /locus_tag="ACZPCR_08285"
     CDS             complement(1489..2523)
                     /locus_tag="ACZPCR_08285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HIR1230910.1"
                     /translation="MKKKFLAVLSCGLAATFLFGCSNNASQKAETTAAQTEAAKESQK
                     PSEETAEKTGTDTASEGGMTFGVTYWIESDFFKTVADSITKAAEAEGNKTVVVDAQQD
                     STKQLQVVEDFIAQDVDAVFLNPVDKDAIEPALQKLDEAGIPVVNFDSAVGNLDLVDA
                     YVATDNIQAGKLCGEAMLKDFPDGGKIAVLNYPANSACVDREKGFLETIEGKGFEIVE
                     TFDAEGTVEKGQNITSDILQAHPDLDAIFSINDQAGMGAYAACMTSGADVAIYGVDGA
                     PEAKQVIAKEGSIYRMTAAQSPIKIGTQCYETVKGILAGQEPEQFQIDVPAFAIDSEN
                     IAEYLNAGWQ"
     gene            complement(2594..4120)
                     /gene="xylB"
                     /locus_tag="ACZPCR_08290"
     CDS             complement(2594..4120)
                     /gene="xylB"
                     /locus_tag="ACZPCR_08290"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0005997 - xylulose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HIR1230911.1"
                     /translation="MKQYFIGIDIGTSAAKTLLMDEHGVVTAQVSREYPLYQPANGWA
                     EQDPEDWRNAVFSAVRELMERSQAEPEQVMGIGFSGQMHGLVMLDENGKPIRRSIIWC
                     DQRSAAQTQEMCSLMPEEKWLEITANPPIAAWTAAKILWVRKEEPENWEKCRHILLPK
                     DYIRYCLTGVFATDVSDASGMQLLDVKNRVWSDTVLECLSIDKAMLAQVFESQEVTGT
                     LLPEAAKELGLTEKVKVVAGAADNAAAAVGIGVVRDGESFTTIGTSALLYTHLERYTP
                     VPGGGLHLCCAAVPGSWFTMGGPQAAGLSLEWFKDFYCQDMIEQADRENRNVYQLINE
                     AAEKIPAGSERLIYMPYLMGERTPHMNPKCRGAFVGLNIIHQKSHLLRAIMEGIAYSL
                     ADCNALLKETGTEISSMKACGGGSKSKLWRQILADLYECEIQTLAEEEGPAYGAAILA
                     GVGTGVFPDVSWACRQFIKIGDTVKPDKEEAELYKRYHAVYDSLYCHMTKDFEALYEL
                     "
     gene            complement(4095..4796)
                     /locus_tag="ACZPCR_08295"
     CDS             complement(4095..4796)
                     /locus_tag="ACZPCR_08295"
                     /inference="COORDINATES: protein motif:HMM:NF004076.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HIR1230912.1"
                     /translation="MVQLAPSIYAADYYSLGEQMKVMEEEGISILHLDVMDGQFVPGF
                     SFGPEFIAKLRPHSRQHFDVHLMTQQPQNLIRQCVESGADTILLHWEAFEDEKSLLNA
                     VESIHNFEKKAGIVLNPETELSALTPDLWKKADKLQLMTTRPGRKGQSFLTFSLERFR
                     QAKLTAEQLDVQTELQADGGVNLSNIQQLIASGAETFVVGNGLFTGKLRENIKAYQAV
                     LTEGRAGDEAVFYRD"
     gene            complement(4832..5674)
                     /locus_tag="ACZPCR_08300"
     CDS             complement(4832..5674)
                     /locus_tag="ACZPCR_08300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HIR1230913.1"
                     /translation="MNELLVKIRFLIPSLPRAEKAFAQALLENPEAITQLTLAAIAAE
                     SGSSEASIIRFCKRMGYHGYSGLKEAFTAAIAEGEEIHEEGIEETDGIEVILKKVFQS
                     NVQTLQNTMVLANDGYQAALDAIISAKSIHFFGVGDAFAACQFAFMKFCRLGIPCSAY
                     SDVMLQYITADNLRPGDVALAISYEGRSRNVVQAMKIAKLRGATTISITKMNKSPLLK
                     YTDISLFTSVSDLTVGRDKVTRRVADQFILDVLYLGYITKTKRDYSKRLKRTQTAIDC
                     NKLM"
     gene            6073..7110
                     /locus_tag="ACZPCR_08305"
     CDS             6073..7110
                     /locus_tag="ACZPCR_08305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006782106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004793 - threonine aldolase activity
                     [Evidence IEA];
                     GO_process: GO:0006567 - L-threonine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine aldolase family protein"
                     /protein_id="HIR1230914.1"
                     /translation="MNFHKFTNDYSEGAHPRILEAMINANLTQNPGYGLDSHCEKARE
                     LIIKECSGPNGVRSDLAVHFLVGGTQTNKTVIDAALRPHQAVIAASTGHVNVHETGAI
                     EATGHKVIAIPHTDGKLTVPEIEKALAAHPDEHMVQPKMVYISNTTELGTQYTKKELE
                     DLSRLCRRKNLYLFLDGARLGSALTSSVNDLTLADLADLTDVFYIGGTKNGALMGEAL
                     VIRNDRIKEDFRYFIKQNGALLAKGWLLGIQFETLFTDGLFYEMASHANEMAQLIRQG
                     FTDRGFSFLAPSLSNQLFPIVDDRLAEILMSQWGGLCEKKTDENHTAVRLVTSWATPK
                     DAAEELLKALD"
     gene            complement(7298..8542)
                     /locus_tag="ACZPCR_08310"
     CDS             complement(7298..8542)
                     /locus_tag="ACZPCR_08310"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HIR1230915.1"
                     /translation="MENKNKFWKGVMAGVFATAFVCLAAVAASVGIYMFGSQTLTRAQ
                     NSSGEASGEAASLDMEQVNQKLGVILDLINEVYLFDTDPSLEEAGIYKGLMYSLGDLY
                     ADYYTPEEMQAMQEQTTGEYCGIGAMISQDRMTNVATVTKVYKDSPAEEGGLLPGDVL
                     YKVGDLDVTAMDLDTIVEQHVRGEENTSVSMTVYRNGEEVELTMVRRQLEIQTVEYEM
                     LDEKTGYLEVSEFDTVTADQFKAGLDQLTSQGMERLVLDLRNNPGGELNAAVAMIDYL
                     LPDGETIVSIADKNGEGETYSSEDGHQMDLPVAILVNGNSASASEVFTGAMKDHDRAV
                     VVGTTTFGKGIVQSLYTLQDGSGIKLTTEHYYTPEGTDIHGAGIEPDVSVELKEGLET
                     MIEIPKDQDNQLQAAVEALNQK"
     gene            complement(8574..9773)
                     /locus_tag="ACZPCR_08315"
     CDS             complement(8574..9773)
                     /locus_tag="ACZPCR_08315"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008726078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="murein hydrolase activator EnvC family protein"
                     /protein_id="HIR1230916.1"
                     /translation="MRKGRWKAGVVLLAAALWAVPVQAAKKGDIDSAKDQISSLEEEK
                     KKTEETIKNLEGLKADTESYVRQLDSDLEELDQELTSLSGQITDKEAEIDETKKQLEQ
                     AKKTEEEQYNSMKLRIKYMYEKGDTSYLDLLMESGSLSEMLNRAEYIQQISSYDRKQL
                     ARYGEIKDEIAESEKKLEAEHADLLSLKDKTEAKQSSVERLVNEKTKELQKYQNQISA
                     NEAQLASYQADIKAQEDRIKQIEAELKRQEEEAKKKAEAQGQTYKPVSIGNINFVWPC
                     PSSGRITSGFGGRTSPTEGASSNHQGIDIGASSGSDIIAAADGTVTISTYSYSAGNYI
                     MINHGGGVSTVYMHCSKLLVSAGETVKKGQVIAKVGSTGYSTGPHLHFGVRLNGSYVN
                     PSKYVSP"
     gene            complement(9786..10694)
                     /gene="ftsX"
                     /locus_tag="ACZPCR_08320"
     CDS             complement(9786..10694)
                     /gene="ftsX"
                     /locus_tag="ACZPCR_08320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003526538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HIR1230917.1"
                     /translation="MRIGTFWYCLKEGIKNIGKNIWFSLASMAIISACIFLFCIFFSL
                     VANVQYMVRNVETTVGITVFFDEDLGEAEIKAIGDQIGKRPEVKEYSYVSPEEAWDSF
                     KEDYFEGMEELAAGFEEDNPLADSASYTIFLKDLTKQEEMVSWLKSLDGVRRVNYSKD
                     VAAGMTDFNKMLGGVSLSIILLLLAVAVFLISNTIRTAASFRKNENRIMRLIGATNFM
                     IRSPFVVEGIIIGLAGAAVPLGLIYVVYKQAAIYLEQNFQQISSLIVFLPIQEIFPYM
                     AGVAMVLGVGIGFVGSFFTIRRHLKV"
     gene            complement(10931..11584)
                     /gene="ftsE"
                     /locus_tag="ACZPCR_08325"
                     /pseudo
     CDS             complement(10931..11584)
                     /gene="ftsE"
                     /locus_tag="ACZPCR_08325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566964.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
     gene            complement(11750..12838)
                     /locus_tag="ACZPCR_08330"
     CDS             complement(11750..12838)
                     /locus_tag="ACZPCR_08330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HIR1230918.1"
                     /translation="MISNQILQTNIEGLKGITRVDLCICDTEGKILASTFAGAEEYEH
                     AILAFVESPADSQVLQGHQFFKVFDEHQLEYVLLAKGGSDDVYMVGKMAAFQIQNLLV
                     AYKERFDKDNFVKNLLLDNLLLVDIYNRAKKLHIETNVKRVVFIIETQMEKDGNALET
                     MRSLFSSKTRDFITAVDEKNIILVREVKQGETYSDLEKTANMLLDMLNTEAMSKVNVA
                     FGTIVNEIKDVSRSYKEAKMALDVGKIFYSTKNVVAYSRLGIGRLIYQLPLPLCRMFI
                     KEIFDGKSPDDFDEETLTTINKFFENSLNVSETSRQLYIHRNTLVYRLDKLQKSTGLD
                     LRVFEDAITFKIALMVVKYMKYMENLDY"
     gene            complement(13044..14153)
                     /locus_tag="ACZPCR_08335"
     CDS             complement(13044..14153)
                     /locus_tag="ACZPCR_08335"
                     /inference="COORDINATES: protein motif:HMM:NF012235.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1230919.1"
                     /translation="MAGLSLKNVTKYYQNGHVAVRDFTLDIADSEFVVLVGPEGCGRS
                     TVLRMIAGLEDISSGELLIDGKRVNEEGTREREVAMLFENCVLYPQMSVYENMAFGLR
                     LKRLPEQEIDRAVRAMAEYLNLTGELDALPEQLTEAQRQLAAVGRALVKKPQVFLMDR
                     PFSSRNAKIKEDMQNELIALYKTLKTTSIYATVDPVEAMKMGTKVVVMNEGTIQQAGT
                     PKEIYDTPANRFVAGFMGNPGVNMLDLRIGEEDGRLYGELKGTKVALPEAFSERLRRE
                     DYIGKELVLGIRPEHASVGDRDPKDPSNEVFTALAEDCQISEDGLLLTLSGEEGTFTI
                     RLSEPMKRMPKDKVSFYVDKKRFLFFDKETGRIIL"
     gene            complement(14561..14632)
                     /locus_tag="ACZPCR_08340"
     tRNA            complement(14561..14632)
                     /locus_tag="ACZPCR_08340"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14598..14600),aa:Gln,seq:ctg)
     gene            complement(14745..15017)
                     /locus_tag="ACZPCR_08345"
     CDS             complement(14745..15017)
                     /locus_tag="ACZPCR_08345"
                     /inference="COORDINATES: protein motif:HMM:NF027249.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HIR1230920.1"
                     /translation="MKFAYPAVFTQENDGKYKVVFPDLEGCAAEGDTLEEAIEKAKEA
                     ESAWIEVELEDSWELPGITHRDDMELPEGSFMREVAVRIKLVDDYD"
     gene            complement(15036..17357)
                     /locus_tag="ACZPCR_08350"
     CDS             complement(15036..17357)
                     /locus_tag="ACZPCR_08350"
                     /EC_number="2.7.7.65"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: protein motif:HMM:NF012772.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA];
                     GO_function: GO:0071111 - cyclic-guanylate-specific
                     phosphodiesterase activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HIR1230921.1"
                     /translation="MEKQGMGTYSREREAYLDQIDHQRRRRKHHALLLGIIALGVILF
                     AAVCTISMKMEEIHSKKQYVKNYTEQRGSLLGIELENGRAEMTSLRESVERIGSWDIV
                     AEFLKKKREVYQLDFLAVYDAPTGTFLMEGEARDSESREAFRACGISQKAAKLGECVA
                     DIVNGSLLYAVPISQDGQVRGMMWAGDRTDSLNSILSTKAFNGESVSYLVAEDGRELL
                     ASHSTADSRLWSQMASQTEDGRSSEVAGTVMNALRSGESGVFRFRTSDHKPYYLSYGP
                     TGVNGWMTVTILPSSLFMTFSDWYVILMLGSLLTALAVFGAFFLQLLRSSNDNEKRLE
                     ELALTDEVTGGINKIDFRMKYHELCRKGEADQFAVALLDCVDFKAINETQGLKMGDEM
                     LAYFYQVIRRRLSQERGEFVSRTEMDYFFLCMREKSPSVIAARLEEIVREINEFSHRR
                     DLMLPGRRIMFRRGVSFVQDNQTDISIIQDQARIALKGQTEPEVCVFFDAAAAEKIQK
                     EREIEQLFDRAVQNEEFQVYFQPKVSLSQNRITGAEALVRWNRPGSGVISPGEFIPVL
                     ERSGKIRALDRYVFEKVCIWLGERKRREQETFPVSVNLSRSNFIYDSFLEEFIEIADR
                     HQADRNMIELEVTETVFLTEENIQKVKREIRAIHDCGFRCALDDFGVGFSSLTLLKEF
                     NIDSLKMDRSFFSDLDNAKTRNVISCILELAEQLDMETVAEGIETEEQIDSLRRLGCD
                     VVQGYYFSRPLPQEQFERWIQEFEEIHVREDRE"
     gene            complement(17552..19009)
                     /locus_tag="ACZPCR_08355"
     CDS             complement(17552..19009)
                     /locus_tag="ACZPCR_08355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009295777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma-I factor RsgI family protein"
                     /protein_id="HIR1230922.1"
                     /translation="MADGHEKWNNDEIASHLKSAVETLTPNVLDQIDLSAPQLLYMEP
                     PRHLKTYRRMRRAVTAAAACLCIAALYGGGVRWQNTRVESVIGLDVNPSIEISVNRKD
                     EILEAEPLNDDGAEVLADMDLDGVDLNIGVNAIIGSMVRCGYLDELDNAILVTVSNDD
                     REKASVLRQDVVTDIESSLEAHKVNAVVYDQQATDMKEITEISNQYGISYGKACFLYE
                     LVEENGLTEKELESFAAMTMEEIAKEIADRSYQVGTNTGREEPPAGATVVTRPETSEP
                     TESQTEESSSESQTPSETQSAKPPASSSAAQPPSETGDTEEDNEGGRKARIDYVDYYE
                     GILEITFKEKVKWKNPTVSVTDADGSSCSARITDTGSDSCQIEISGIVGGESYTVALN
                     GVKPRENGSYSSVKAYFDAPDISGDAMENGSDEPEDEENITEPSESLPEPETSLPEET
                     QPETETGEGGHQAETQGDGESLPKQTEPSEAETGI"
     gene            complement(19012..19596)
                     /locus_tag="ACZPCR_08360"
     CDS             complement(19012..19596)
                     /locus_tag="ACZPCR_08360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1230923.1"
                     /translation="MFLMGMFAVMEEPENYGRLSDEKLLLKIAKGDQEAFRQLYQNTD
                     KTMYSFILSVVRNPQDAEEIMQETYLRIWTSAGSYQAQGKPLAWMFTIARNLCYMRFR
                     DQKHESDIGLSDLSEMETGEFCPQIENAADKVVLHAALHILKEEERQIVLLHTAAGLK
                     HREIAADLGMPLATVLSKYNRAMKKLKNHLREEG"
     gene            complement(19721..20527)
                     /gene="truA"
                     /locus_tag="ACZPCR_08365"
     CDS             complement(19721..20527)
                     /gene="truA"
                     /locus_tag="ACZPCR_08365"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HIR1230924.1"
                     /translation="MYRNIKLILQYDGSRYGGWQKQGNSQNTIQGKLESILEKMTGEP
                     ILVHGSGRTDAGVHALGQTANVHLDENCLKNNKNPEFLKIFDSFHGSDELPKAVMEYL
                     NRYLPEDIAVIGAEEVLERFHSRLSAVSKTYLYRVETAGKKNVFERKYAYGLGEKLDI
                     GAMRQMAVVLEGTHDFRGFSSLKRTKKSTVRTLQSIEIEQKGSVVELSFTGDGFLYNM
                     VRILTGTLLEAGLHRRTPESAEEIFKSLDREQAGFTAPAEGLFLKCVRYE"
     gene            complement(20549..20998)
                     /locus_tag="ACZPCR_08370"
     CDS             complement(20549..20998)
                     /locus_tag="ACZPCR_08370"
                     /inference="COORDINATES: protein motif:HMM:NF016763.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HIR1230925.1"
                     /translation="MKRQIGWHAALLLYVAFIYFNSLTPAALSSQESSSVLRLIHGVL
                     GELGLAAPWITEHVVRKCAHFGEYFILGMLLTQSLNGTGLKREGRVLGQLCLTAAVPL
                     IDETLQLFTPGRSGQISDVWLDMGGAAAGTVFFFLAAAALRRVKRIE"
     assembly_gap    21234..21243
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            21509..21688
                     /locus_tag="ACZPCR_08375"
     CDS             21509..21688
                     /locus_tag="ACZPCR_08375"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230926.1"
                     /translation="MSENDKKDLIHEVNVASSLYSFDTETKTAEAEHKHPAEGTLERE
                     LTDVSLLYNLETKNK"
     gene            complement(22018..>22220)
                     /locus_tag="ACZPCR_08380"
     CDS             complement(22018..>22220)
                     /locus_tag="ACZPCR_08380"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230927.1"
                     /translation="DNFEPIPFSLNNGEYQEYYEIDLQASDTPLITEDNLITINVLEY
                     KNNDMCVLLTNEDFVFAKRFQF"
BASE COUNT         5075 a         6463 c         4533 g         6139 t
ORIGIN      
        1 ggaaccagtt ggctttttca tgaaaacggt cccggccaat cgcagccggg gtggagaaaa
       61 caatgagtga taagctctgg catctcagaa gaaataaaga tcacagacag gccctccgct
      121 gtcaggcgat caattaaatg ataaatatcc gcctttgtct ttacgtcaat gcctctagtc
      181 ggttcgtcca agatcaaaat tttctctgtg gcaagaagcc accggctgat aataactttt
      241 tgctgattgc ctccgctcag tcttccgatc ggctgttcaa ttccagcata ttttgtttcc
      301 atcacctgat ctacgtatgt ccgaatcaga gaaatctctt tttcccggct gtatgctcct
      361 ccctttaaaa actgatccag cacttcaatc gtggtattaa agcgtattcc ctgaacagca
      421 aaaattccct cttttttcct gtcctccgga accaggccaa gaccgcagtt catggcatct
      481 tttacattct ttatctggac cttcttccca ttcacgagga tttctccaga gtcctttctc
      541 ctgagaccaa acaaagcctc catcgtctct gaacggcccg atcccaccag acccgaaaat
      601 cccagtacct ctcccttttt cagttcaaag gaaacatctc tgacttcctt tcctgctgcc
      661 agatgatgaa cagaaagcac ggtttcctct ccggaatggt tgtgcttgtc gtacaaatct
      721 cccagagaac gccctaccat cagactcacc agatgatcgt gggttgtatc ctttgtcacc
      781 actgtcgcaa tatactctcc atcgcgcatt actgtaatcc ggtctgcgat ttcatccagc
      841 tctgacatcc tgtggctgat atagataatg ccgactccct tttccttcag cctccgaatt
      901 gccttaaaga gaacctccac ctctgtgtct gtcagggagg aggtaggctc gtccattact
      961 ataattttag cgccgaagga gattgctctt gcaatctcca ccatctgctg tttcgcaatg
     1021 ttgagccttc ctacctgctc atccggctgg atatctaatt ccatttcctt cagaaaggca
     1081 gccgtatccc ggttcatttt cgctgtatct acagtccctc gcttcgtctt cggctcctgt
     1141 cccaggaaaa tattctctgc cacagtcata tagggaatca gcatcagttc ctggtgaatc
     1201 acacggattc catggcttct ggcgctctcc acacttgtga tctctgtctt attcccctca
     1261 atgtaaatcg ttccctcatc ttttgtgtag gctccgccaa gtatcttaat cagcgtggat
     1321 tttcctgctc cattctcccc taaaagagcg tgtacctccc cgtgcttcac agtcagctcc
     1381 acacggttca gcactctgac tcctgagaag gatttggaaa ttccctccat cctcagtaat
     1441 tcttccatcc tctgccgctc cttgtctgta tcccttaacc tctgcttctt actgccatcc
     1501 tgcgttcaga tattcggcaa tattctcact gtcaatcgca aaagccggaa catcaatctg
     1561 gaactgctct ggctcctgtc ctgccagaat tcccttaact gtctcatagc actgagttcc
     1621 aatcttaatc ggagactggg ctgctgtcat ccggtagata ctgccttcct tggcaattac
     1681 ctgctttgcc tccggagctc cgtctacgcc atagatagcc acgtcggctc ctgatgtcat
     1741 gcaggctgca taagcgccca tacccgcctg atcattgatg gagaaaattg cgtctaagtc
     1801 tgggtgtgcc tgtaaaatat cacttgtaat attctgtccc ttctcaacgg ttccctctgc
     1861 gtcaaaggtt tctacgatct caaatccctt accctcaatg gtctctaaga agcctttctc
     1921 tctgtcaacg caggcactgt tagccggata gttaagtacg gcaatctttc cgccgtccgg
     1981 gaagtccttc agcatggctt ctccgcacag cttacctgcc tgaatattat cagtagctac
     2041 atacgcgtct accagatcca gatttcctac tgctgaatca aagttaacca ctggaattcc
     2101 agcctcgtcc agtttctgaa gagccggttc aattgcatcc ttgtcaacag gatttaaaaa
     2161 tactgcgtct acgtcctgag caataaaatc ctctaccacc tgaagctgtt ttgtgctgtc
     2221 ctgctgcgcg tctaccacaa ctgttttatt tccctctgcc tcagctgcct ttgtgataga
     2281 atcagccact gtcttgaaga agtcagactc gatccagtag gtgacaccaa aggtcattcc
     2341 tccctctgaa gcggtgtctg tccccgtctt ttctgcagtt tcctcagacg gtttctggct
     2401 ctcttttgca gcctctgtct gtgcagctgt tgtctccgcc ttctgagacg cattgtttga
     2461 gcagccaaat aaaaatgttg ctgctaatcc gcatgataac actgctaaaa atttcttctt
     2521 catcttgttt tcctcctctt acattatata aatcatttct caatatctat ttcgaagtct
     2581 gcaaaagctt attctaaagc tcatacagtg cctcaaaatc ctttgtcata tggcaataca
     2641 gactgtcgta gactgcatga taccttttat aaagctctgc ttcttctttg tccggcttca
     2701 ctgtatcgcc tatttttata aactgcctgc atgcccagga aacgtccggg aatacgccgg
     2761 ttcccactcc ggctaaaata gccgcgccgt aggcagggcc ctcctcctca gcaagtgtct
     2821 gtatttcaca ctcgtaaaga tctgccagaa tctgacgcca cagtttgctc ttactgcctc
     2881 ctccgcaggc cttcatagaa gaaatttctg ttcccgtttc ctttaaaagc gcattgcagt
     2941 ccgccaggga ataggcgatt ccttccatga ttgcccgcag cagatgagat ttctggtgaa
     3001 taatgttaag tcctacaaaa gcccctctgc atttggggtt catatgggga gttctctccc
     3061 ccatcaggta tggcatatag atcagccgtt cgcttccagc cggaattttt tccgccgcct
     3121 cattgatcag ctgataaaca tttctgttct ctctgtccgc ctgttctatc atatcctggc
     3181 aatagaaatc tttaaaccat tccagggaaa gccctgccgc ctggggacct cccatggtaa
     3241 accagcttcc aggcactgcg gcgcagcaca ggtgaagtcc tcctccaggc acaggcgtat
     3301 atcgttccag gtgcgtatat aaaagagcgg aagttcctat ggtcgtaaag ctttcgccgt
     3361 ccctgaccac tccgattccc acagctgctg ccgcattatc cgccgctccc gccaccacct
     3421 tgactttctc tgtcaatccc agctcttttg ctgcctccgg aagcagagtt cccgttacct
     3481 cctgagactc aaatacctga gccagcattg ctttatcaat agagagacat tccagtacag
     3541 tatctgacca aactctgttt tttacatcga gcagctgcat tcccgacgcg tcggacacgt
     3601 ccgttgcaaa aactccagtg agacagtaac gtatataatc cttgggcagc agaatgtgtc
     3661 ggcatttttc ccagttttcc ggttcttcct tcctcaccca taaaatttta gctgccgtcc
     3721 aggcggcaat cggaggattt gctgtaattt ccagccattt ctcttccggc atcagagaac
     3781 acatttcttg cgtctgcgct gccgatctct gatcgcacca gataatagag cgccgaattg
     3841 gttttccgtt ttcatccagc ataaccagtc catgcatctg gccggagaag ccgattccca
     3901 taacctgctc cggctctgcc tgagagcgct ccatcagttc cctgactgcc gaaaatacag
     3961 cgtttctcca atcctccgga tcctgctccg cccatccatt tgctggctga tagagaggat
     4021 attctctgga aacctgagct gttactactc catgctcatc cataaggagc gttttagctg
     4081 cgcttgtccc tatatcaatc cctataaaat actgcttcat ctcctgccct cccttctgtc
     4141 aaaacagctt gatatgcctt aatattttcc cgaagttttc cggtaaacag tccatttccc
     4201 actacgaaag tttccgctcc gctggcaatc agctgctgta tattagacaa attcacaccg
     4261 ccgtccgctt gaagctctgt ctgcacatcc agctgttctg ctgtcagctt ggcctgcctg
     4321 aaccgctcca gagaaaaagt taaaaagctc tggccttttc gtccgggcct tgtagtcatc
     4381 agctgaagct tgtctgcctt cttccataaa tctggtgtta aagcagaaag ctctgtctcc
     4441 ggattcaaaa caataccagc ttttttttca aaattgtgaa tgctttccac tgcgttcaga
     4501 agactttttt catcctcaaa cgcctcccaa tggagaagaa tcgtatcggc tcctgactcc
     4561 acacactggc ggattaaatt ttgaggctgc tgtgtcatta aatggacgtc aaaatgctgc
     4621 ctgctgtgcg gtctgagctt tgcaataaac tctggcccaa atgaaaatcc gggaacaaac
     4681 tgcccgtcca tcacatccag atggagaata gagattccct cctcctccat caccttcatc
     4741 tgttctccca ggctgtaata atcagccgca taaattgacg gcgcaagctg taccatatct
     4801 gtcacctttt ctatctttta tttctgtctt tttacatcaa tttattgcag tcaatggctg
     4861 tctgggtccg cttcagccgt ttggagtaat ctctttttgt ctttgtgata tagcccaaat
     4921 aaagcacatc taaaataaat tgatctgcca ctcttcttgt caccttatcc ctccctactg
     4981 tcaaatcgct gacagaggtg aacaggctga tatctgtata ttttaaaagc ggagatttat
     5041 tcatttttgt aatgcttatc gtggttgctc ctctgagctt tgcaattttc atagcctgaa
     5101 ccacatttcg tgatcttccc tcataggaaa tcgccaaagc cacatcccca ggccggagat
     5161 tatctgctgt gatatactga agcatcacat cgctgtaagc agaacacgga attcccagac
     5221 ggcagaattt cataaacgcg aactgacagg ctgcaaatgc atctcctacg ccgaaaaaat
     5281 ggatagattt tgctgaaata atcgcgtcca gcgctgcctg ataaccgtca ttggccaaaa
     5341 ccatggtatt ctgaagtgtc tgaacattgc tctgaaacac ttttttcaat ataacttcta
     5401 taccatctgt ttcctcaatt ccctcttcat ggatttcctc tccctctgca atcgccgctg
     5461 taaacgcctc cttcagccct gaatatccgt gatatcccat ccgtttgcag aagcggataa
     5521 ttgaggcctc gctgcttcct gattctgcag caatagccgc cagcgtcagt tgagtaatcg
     5581 cctctggatt ctccaaaagg gcctgggcaa aagccttctc ggctctgggc agcgacggaa
     5641 tcagaaaacg gatttttacc agtaattcgt tcatgttttt cctccagatt caaattccgc
     5701 aaatgaagtt atctgttgaa aaaatcatag catctgcaca atttgaagta aatatgtact
     5761 gtttttttta tatattctac tatattttcc acttttctat tgtatattct gcacaatttt
     5821 tctgcaactt tttcacttgt ttcatttttg atatttcatt atgaagtttt tatgctgcag
     5881 ttttactccg ctctctggtt cattttcgtc tctcgatgaa atgttcgttt agaaaagcag
     5941 aacgcgccgt tttctccctt gacaacctcc ctctcttccc ccaaaataaa agcatacaaa
     6001 atacttacgg cacgctgcgc atcctgccct ttcagacggg ggcgtcctgc cgcgcagttc
     6061 aaggaggcag atatgaattt tcacaaattt accaacgact acagcgaagg ggcccatccc
     6121 agaattttag aggccatgat aaacgccaat ctgactcaga atccaggcta cggtctggac
     6181 tcccactgtg agaaggcgag agaactgatt ataaaagagt gcagcggccc caacggcgtc
     6241 cgctccgatc tggctgtcca ctttctggta ggcggaactc agacaaataa aacggtgatt
     6301 gacgcggctc tgcggcctca ccaggcggtg atcgcagcct ccaccgggca tgtaaacgtc
     6361 cacgaaacag gagcgatcga ggccaccggg cacaaggtta tcgccatccc tcatacagac
     6421 ggaaagctta ctgtccctga aattgagaaa gctctggccg cccatccgga cgaacacatg
     6481 gttcagccga aaatggtcta tatttccaac accactgagc ttggcacaca gtatacaaaa
     6541 aaagagctgg aggacttaag ccgcctctgc cgccggaaaa atctctatct tttcctggac
     6601 ggggcaaggc tgggatctgc tctcacaagc tctgtcaatg atttgacgct ggcggacctg
     6661 gcggatctga ctgacgtatt ttatattgga ggcacaaaaa acggcgctct gatgggggaa
     6721 gctctggtca tacgaaacga ccgcatcaag gaagacttcc gctatttcat caagcagaac
     6781 ggcgctctct tagctaaggg atggctgtta ggaattcagt ttgaaactct gtttacagac
     6841 ggcctgttct acgagatggc ctcccatgcc aatgagatgg cgcagcttat acgtcagggc
     6901 ttcacagaca gaggcttctc cttcctggct ccctccctgt ccaaccagct cttccccatt
     6961 gtagacgaca ggctggcaga aattcttatg agccagtggg gcggactctg cgaaaaaaag
     7021 acagacgaga accataccgc cgtccgcctg gtcacctcct gggctacccc gaaagacgcg
     7081 gcagaggaac tgttaaaggc tcttgactaa aaaaatagac aggtacagtg atgataacga
     7141 ggctttctca gtgaggtttg tgctaatttc cgccaccgag cgaaatgtct gagccgtaag
     7201 gcgagttttc gcgaatggcg gatcacagat gcgcaaaccg aagagaaaac gcagttaatc
     7261 actgtacctg tctatttttc ttaattttct tactttctta cttctgattc agcgcctcca
     7321 cagcggcctg aagctgatta tcctgatctt tcggaatctc aatcatagtt tcaagcccct
     7381 ccttcagctc taccgacaca tccggttcaa ttcccgctcc atgaatatcg gttccctccg
     7441 gggtatagta atgctcggtg gtaagcttaa tgccgcttcc atcctgcaga gtgtacaggg
     7501 actggacaat tccctttcca aacgtagtag tgccaaccac cacggctctg tcatgatcct
     7561 tcatagcccc tgtaaacacc tcagacgcgc tggcggaatt tccgtttact agtatggcca
     7621 caggaagatc catctgatgg ccgtcctcag agctgtaggt ctccccctcg ccgtttttat
     7681 cggcaatgga tacaatcgtc tctccatctg gcagcagata atcaatcatg gccacggccg
     7741 cgttcagctc gccgcctgga ttatttctca gatccagcac cagacgttcc attccctggg
     7801 aagtcagctg atccagacct gccttaaact ggtccgccgt caccgtgtca aactctgaga
     7861 cttccagata tcctgtcttc tcatccagca tttcgtactc cacggtctgg atttccagct
     7921 ggcggcggac catggtaagc tccacttcct cgccgtttct gtatacagtc atggagacag
     7981 aggtattttc ctctccccgc acatgctgct ctacaatggt atccagatcc atggctgtca
     8041 catccagatc tcccaccttg tagagaacgt ctcccgggag cagtcctccc tcctctgccg
     8101 gcgaatcctt gtacaccttg gtaactgtgg ccacatttgt catacgatcc tgggaaatca
     8161 tggctccgat tccgcagtat tcgcctgtgg tctgctcctg catggcctgc atttcctccg
     8221 gcgtgtagta atccgcgtat aaatctccca gactgtacat cagcccttta tagatccccg
     8281 cctcctccag agacggatcg gtgtcaaaca aatagacctc gttgattaaa tccaggatga
     8341 cgcccagctt ctgattgacc tgttccatat caagggaagc cgcctccccg gacgcctcgc
     8401 ctgagctgtt ctgcgccctt gtgagagtct ggctgccgaa catataaatt cccaccgagg
     8461 cggccaccgc cgccaggcat acaaaagctg tggcaaatac gcctgccatg actcccttcc
     8521 agaatttatt tttattttcc attctttcat cctcctgcgt ctgtttcctg ccgctacgga
     8581 cttacgtact tcgacggatt gacatagctg ccgttcagtc tcactccaaa atgaagatgc
     8641 ggtcccgtcg aatagccggt cgatcccact ttggcaatga cctgcccctt tttcaccgtc
     8701 tctcccgctg ataccagaag cttagagcag tgcatgtata cagtcgaaac tccaccgccg
     8761 tggttgatca taatataatt tccggccgag tagctgtatg tagagatagt caccgtgccg
     8821 tctgcagcag cgataatatc gcttcccgac gaagccccga tgtcaattcc ctgatgattg
     8881 ctggacgccc cctctgtcgg agaggttctg ccgccgaagc ccgaggtgat ccgcccgctg
     8941 gacgggcagg gccatacgaa attaatattc ccaatgctga ccggtttata cgtctgtccc
     9001 tgggcctccg ccttcttctt cgcttcctcc tcctggcgtt tcagctccgc ctcaatctgc
     9061 ttaatcctgt cctcctgggc cttaatgtca gcctggtagg aggccagctg ggcctcgttg
     9121 gccgaaatct gattctgata cttctgaagc tccttggtct tttcgtttac cagacgctct
     9181 accgagcttt gcttcgcctc cgtcttatcc ttcagggaaa gaagatctgc gtgctccgcc
     9241 tccagctttt tctcgctctc tgcaatctca tccttgattt cgccgtatct ggccagctgc
     9301 ttcctgtcgt aggaagaaat ctgctggata tactccgccc ggtttaacat ctcggaaaga
     9361 gatccggatt ccatgagaag atccaggtag ctggtatctc ccttctcata catatatttg
     9421 atgcgaagct tcatggaatt gtactgttct tcctccgtct tcttcgcctg ctccagctgc
     9481 ttcttcgtct cgtcaatctc ggcttcctta tccgtgatct gcccggacag agaagtcagc
     9541 tcctgatcaa gctcctccag atcagaatcc agctgtctga cgtagctctc tgtatccgcc
     9601 ttcagcccct ccaggttttt gatcgtctct tctgtcttct tcttttcttc ctccagagag
     9661 gaaatctgat ccttggcgct gtcaatgtcg ccctttttcg ccgcctgaac aggaactgcc
     9721 cagagagccg cggccagaag aaccacccct gctttccatc ttccttttct catccgtatg
     9781 ccctcctaca ccttcagatg cctgcggatt gtgaaaaagc tgcccacaaa gccgattccc
     9841 actcccagta ccatggccac tcctgccata tacgggaaaa tttcctgaat tggcagaaat
     9901 acaatcaggc tggaaatctg ctggaaattc tgttccagat atatggccgc ctgcttatac
     9961 accacataaa tcaggccgag cggcacagcc gctcccgcca gcccgatgat gattccctcc
    10021 accacaaagg gagagcggat catgaaattc gtcgctccga tcaggcgcat aatgcggttt
    10081 tcatttttcc ggaaggacgc cgccgtccgg atggtgttgc tgatcaggaa caccgccact
    10141 gccagaagaa gcagaataat actgagtgac acgccgccta acatcttgtt gaaatctgtc
    10201 attccagccg ccacatcctt ggaatagttg actcttctga ctccgtccag agacttaagc
    10261 caggaaacca tctcctcctg ctttgtcaaa tcctttaaaa aaatcgtgta ggatgcggaa
    10321 tcagctaacg gattatcctc ctcaaatcct gctgccagct cctccattcc ctcaaagtaa
    10381 tcctccttaa aagaatccca ggcctcctcc ggggaaacat aggaatactc cttcacctcc
    10441 ggccgctttc caatctggtc tcctatggcc ttgatctccg cttcgcccag atcctcgtcg
    10501 aaaaatacgg tgattcccac cgttgtctcc acatttctca ccatgtactg gacgttggcc
    10561 accaatgaga aaaaaatgca gaataaaaag atgcaggcag aaataatggc catggatgcc
    10621 agcgaaaacc atatattttt acctatattt ttaatgccct ccttcaggca gtaccaaaat
    10681 gtgcctattc tcatccctgt tttcctcttt ttctgcctct tttgcggcgt ttgctcagct
    10741 catggaaggg aacggtcttt tcactgccag actcgcggga agtctgatcc cagacctcgt
    10801 cctcctcgcg ctccggaagc accacgcttc catttccccc gtaccagccc agatcctggc
    10861 ccgattcgcc gtgcctggtg tgaagctcgt ccacctgcag cgctccgtag tcccagggcg
    10921 gcattacctc gtcgctgatc acggtccccc ggtcaatggt aatcacccgt tttcccatcc
    10981 gctccacaat ctcgtggctg tgagtcacta ctactactgt ggtccctctt cggttgatct
    11041 gctccagcag ccccataatc tccatggaat tgtgggcgtc cagatttccc gtaggctcgt
    11101 ccgccagaag caccgccgga ttgttaatca gagccctggc aatggccact ctctgctgct
    11161 ctcctccaga cagctgatcc ggataggatt tatacttgga ggacagtccc acctgccgca
    11221 gcatggcggg gacgttctcc ttgatctttc tgacaggcag gcccagaacg cgctgggcga
    11281 aggccacgtt ttcatagact gtcatatgct ttaaaaggcg gaaatcctgg aatacgactc
    11341 ccagcatttt cctgtacttc ggcacatagc gtctgggcat tttccccaac tccatgtcgt
    11401 tgacaatcac ctgtccggag gtgggttcca cctccttcaa cagaattttc atcagcgtcg
    11461 acttgccgga accgctgcgc cccataatga acacaaattc accctgctca atatgaatat
    11521 taatgttttt cagggccttg tttttattgt cataggtttt attgagattt ttgatctcta
    11581 tcattcttgt tctcccaaat gcatttaaaa ctcgctccca gagcgttgct ctcctgcgct
    11641 tatgtgcgct gagataaact gctgcaatac atgaggccgc gttatccgca caatagttcc
    11701 ccctcacata ctgcagcagt cagcttttgc ttattctgtt gtccttcttc taatagtcca
    11761 gattttccat atatttcata tatttgacaa ccatcagggc aattttgaag gtgatggcgt
    11821 cctcaaaaac ccgcagatcg agacccgtgc tcttctgaag cttgtccaga cggtacacca
    11881 gcgtatttct gtgaatgtaa agctgcctgg aggtctccga cacgttcaga ctgttctcga
    11941 agaacttatt aatggtcgta agcgtctcct cgtcaaaatc gtccggtgac ttgccgtcaa
    12001 agatttcctt gatgaacatc cggcacagag gaagcggcag ctgatagatc agacggccga
    12061 ttccaagcct gctgtacgcc accacgttct tcgtgctgta gaagattttg cctacgtcca
    12121 gagccatctt ggcttccttg taagagcggg atacgtcctt gatctcattg acaatcgttc
    12181 caaacgctac gtttaccttg gacatggcct ccgtattcag catatctaac agcatattcg
    12241 cagtcttttc cagatcgctg taggtttcgc cctgcttcac ctctctgacc aggataatat
    12301 ttttctcatc taccgctgta ataaaatccc tggtcttgga cgaaaacagg cttctcatcg
    12361 tctccagagc gtttccgtcc ttctccatct gcgtctcgat gatgaacaca actctcttta
    12421 cgttcgtctc aatgtgaagc ttcttggccc tgttgtagat gtccaccaga agcagattgt
    12481 caagaagcag attcttgaca aaattatcct tgtcaaaccg ctctttatac gcaactaaca
    12541 gattctgtat ctggaaggcc gccatcttgc ccaccatgta gacgtcgtcg cttccccctt
    12601 tggcaagcag gacgtactcc agctgatgtt cgtcaaatac cttgaaaaac tggtgtccct
    12661 gaagcacctg gctgtctgcc ggcgattcca caaacgcgag aatcgcatgt tcatactctt
    12721 ccgcaccagc aaatgtggag gccaggatct ttccctctgt atcgcagatg cacagatcca
    12781 ctcttgtaat cccttttaat ccctctatat ttgtctggag tatctgattt gatatcatag
    12841 ccttctctcc ttttctaaat tttccctgat tactatatta atgcaaaacg cggaaaaatg
    12901 aaagagaaat tatcaattct tcacaaaaaa atgaaagaag accgcagtac aaaaaggcag
    12961 gaggccgttt ctcctccgcc tctgagcgga ttcccaaaca gctctcctgc cgccgtattg
    13021 tctctgtaag caggcagccc tgcctacaga atgattcgtc ccgtctcctt gtcaaagaaa
    13081 aggaaccgtt tcttgtccac atagaagctc actttatctt ttggcatcct cttcataggc
    13141 tctgaaaggc ggatcgtaaa ggttccctct tcccccgaca gcgtcagaag aaggccgtcc
    13201 tcggaaatct ggcagtcctc tgccagggct gtgaacacct cgttggacgg atctttcgga
    13261 tctctgtctc ccacagacgc atgctccggc cggatgccga gcacaagctc ttttcctatg
    13321 taatcttccc ttctgagacg ctctgagaag gcctccggaa gcgccacctt tgtccccttc
    13381 agctctccgt aaaggcggcc gtcctcctcg ccaatccgga gatccagcat attcacgcca
    13441 ggatttccca taaatccggc cacaaagcgg ttggcaggag tgtcatagat ttccttcgga
    13501 gtgccggcct gctgaatggt tccctcgttc atcactacca ccttcgtccc catcttcatg
    13561 gcctctaccg gatccactgt ggcataaata gacgtggttt ttaacgtctt gtaaagagca
    13621 atcagctcat tctgcatgtc ttccttaatc tttgcgttcc ggctggagaa cggtctgtcc
    13681 attaaaaata cctgcggttt tttcacgaga gcccgtccca ctgccgccag ctgtctctgg
    13741 gcctctgtca gctgctccgg cagggcgtcc agctctccag tcagattcag gtattcagcc
    13801 atggcgcgga ccgccctgtc aatctcctgt tccggaagac gctttaaccg gagcccgaaa
    13861 gccatatttt catagacaga catctgcgga tacaaaacgc agttttcaaa gagcatggcc
    13921 acctctctct ccctggttcc ctcctcgttg actctctttc cgtctatcaa aagctctccg
    13981 gaggagatat cctccagccc cgcgatcatg cgcagcacgg tggaacggcc gcagccctcc
    14041 ggcccaacca gaaccacaaa ttccgaatct gctatatcaa gggtaaaatc tctcactgcc
    14101 acatgcccgt tctgatagta ctttgtaaca ttcttcagcg acaatcctgc catccttttc
    14161 ctcctaaacc cgcctgaaag gttcctttcg tatctgcttt gcccgcctaa atcggcacga
    14221 tattctatcg tcagctatta tatcacgctt cctccgggcg agctattgtc tcaactgcca
    14281 aaaaacgcct gtttttttgt ctatcttgca ggctctctcc taaaaactgt tcgatctgtc
    14341 aaatattccc tccgtccttc ccaggattcc atataaaatc attagaatcc gtggtttttt
    14401 tctccatatg aaatagtttc tgtttaaatt tcacaatgag aaatgaaatc cggcggcttt
    14461 gcagggcgta ttgaacggac agcagaaatc agaacgcaaa atcaaaatgc aaaaaggccg
    14521 gttctctgct ttcgcagaaa accggccttt tcccatttaa ctggggtaca aggattcgaa
    14581 ccttgaaatg acggagtcag agtccgttgc cttaccattt ggcgataccc caacaacgag
    14641 tgttattata ctatagcttc cgactcccgt caactgtttt tttgaaattt ttttattttt
    14701 ttctccgcct gcccaagcag ccgctttccg catctgtttg gcccttaatc gtagtcgtcc
    14761 accagcttaa ttcttacggc cacctctcgc ataaaacttc cctccggaag ctccatatcg
    14821 tctctgtggg taatccccgg aagctcccag ctgtcctcca gctccacctc aatccaagcc
    14881 gattctgcct cctttgcctt ctcaatcgct tcctccaaag tatctccttc tgcggcgcag
    14941 ccctccagat cgggaaatac caccttatat tttccatcgt tttcctgtgt aaatactgcc
    15001 ggatatgcaa atttcactgt ttttcctcct cttatctatt ctctgtcctc ccggacatga
    15061 atctcctcaa attcctgaat ccatctttca aactgctcct gcggaagcgg tctggaaaaa
    15121 tagtatccct gcacaacgtc gcacccaagc ctcctcaggg aatcgatctg ctcctccgtc
    15181 tcgattccct ctgccacggt ttccatgtcc agctgttctg ccagctccag aatgcagctg
    15241 atcacatttc tggtcttggc gttgtcaaga tccgagaaga aggatcgatc cattttcagg
    15301 gaatcaatat taaattcctt taagagcgtc agcgaggaga agcctacgcc gaaatcgtcc
    15361 agcgcgcatc gaaagccgca gtcatggatc gcccttatct cccgcttcac cttctgtata
    15421 ttttcctctg tcagaaagac ggtctctgtc acctcaagct ctatcatatt cctgtctgcc
    15481 tgatggcggt ctgcaatctc tatgaactcc tctaaaaagc tgtcatagat aaaattgctt
    15541 ctggaaagat tgactgaaac ggggaacgtc tcctgctctc ttcgttttct ctctcccagc
    15601 cagatgcaga ctttctcaaa tacatatcga tccagggccc ggattttccc gctccgctcc
    15661 agcacaggaa taaactcgcc cggagatatc actccgcttc caggccggtt ccaccgcacc
    15721 agagcctccg cccctgtaat tctattctgg ctcagactca ccttcggctg gaaataaacc
    15781 tgaaattctt cattctgcac cgcccggtca aagagctgtt caatctcccg ctctttctga
    15841 atcttttcgg cggctgccgc gtcaaaaaat acgcagacct ccggctctgt ctggcccttc
    15901 agcgcaattc tggcctgatc ctggataatg gagatatccg tctgattatc ctgcacaaag
    15961 ctgactcctc tgcggaacat aatcctgcgt cccgggagca tcagatccct gcggtggctg
    16021 aattcgttga tttcccttac aatctcctcc aggcgcgcgg cgatgaccga cggacttttc
    16081 tcccgcatgc acaggaagaa atagtccatc tctgtccttg agacaaactc tcccctctcc
    16141 tggctgagac gcctgcggat gacctggtag aagtaagcca gcatctcgtc ccccatcttc
    16201 agcccctgtg tttcattgat tgccttgaag tctacacagt ccagaagggc gactgcaaac
    16261 tgatccgcct ccccttttct gcacagctca tgatatttca tccgaaaatc gattttgtta
    16321 atgccgccag tgacttcgtc cgtcagagcc agctcctcca gacgcttttc attgtcattg
    16381 gagctgcgca gcagctgaag gaaaaaggct ccgaatacgg ccagcgccgt cagaaggctg
    16441 cccagcatta aaatgacata ccagtcagaa aaggtcataa acagagacga cggaagaatc
    16501 gtcaccgtca tccagccgtt cactcctgtg ggaccatagg ataaatagta gggcttgtgg
    16561 tccgaggtgc ggaaccggaa tactccgctc tccccggatc gcagcgcatt catcaccgtc
    16621 ccggccacct ccgatgacct cccatcctct gtctgagacg ccatctggct ccagagccgg
    16681 ctgtccgctg tggaatggga agccagaagc tctcttccgt cctctgcaac cagatagctg
    16741 acgctctcgc cattgaaagc tttcgtgctc agaatactgt tcagactgtc cgtcctgtct
    16801 ccggcccaca tcatgcctct cacctgtcca tcctggctga tggggactgc atagagaagg
    16861 cttccgttca caatatctgc cacgcattct cccagctttg ccgccttctg cgatattccg
    16921 caggcccgaa aggcttccct gctttcagag tccctggcct ccccctccat cagaaaggtt
    16981 cccgtagggg cgtcgtacac cgccaaaaag tccagctggt acacctcccg ctttttcttc
    17041 aggaattccg ccacaatatc ccagctgcca atccgctcca cagactcccg caggctggtc
    17101 atttccgccc tgccgttttc cagctcaatc cccagaaggc tgcctctctg ctctgtataa
    17161 tttttcacat actgcttttt ggaatgaatt tcctccattt tcatggaaat cgtgcatact
    17221 gccgcaaata agataactcc cagggcaata atccccagaa gaagcgcatg gtgcttccgg
    17281 cgtctcctct gatgatcgat ctgatccaga tacgcctccc gctctctgct gtacgtcccc
    17341 atcccctgtt tttccatgtg tttttctttg tatttcaatc ctcttctccc gtatcctgca
    17401 tcctccaatg ggcagttttt cagtaaagcc tatggctatt ataaaaaaac actgtttcat
    17461 ctgtcaagac aaagagaatg gcagaaccgg ccgtcatccg gctctgcgcc gtttctggcc
    17521 cgattctgcc tgagcagctt ctgtttctat tctatattcc cgtctctgct tccgacggct
    17581 ctgtctgctt aggaaggctt tcgccgtctc cctgcgtctc cgcctgatgg ccgccttctc
    17641 ccgtttctgt ctccggctgc gtctcctccg gcagagaagt ctccggctct ggaagcgatt
    17701 ctgacggctc tgtgatgttc tcttcatcct ctggctcgtc agaaccgttt tccatggcgt
    17761 ctccgctgat atccggcgcg tcgaaatatg ccttcacaga gctgtaagag ccgttctctc
    17821 tgggcttcac tccatttaag gcaacggtgt aggactctcc tcccacaatg ccgcttattt
    17881 caatctggca gctgtcagaa cctgtgtctg tgattctggc cgagcagctt gagccgtctg
    17941 cgtcagtaac ggacactgta ggattcttcc acttcacctt ctccttaaac gtgatctcca
    18001 gaatcccctc atagtagtcc acatagtcta ttctggcctt tcttccgccc tcattgtcct
    18061 cttcagtatc tccggtctca gacggaggct gagcggctga ggaggaggcc ggaggctttg
    18121 cgctctgcgt ctcggacgga gtctggctct cagaggagga ttcctccgtc tggctctctg
    18181 tcggttctga cgtctcaggc cgcgtaacga ccgtcgcgcc ggccggtggt tcctctcttc
    18241 cggtattggt tcccacctga taggaacgat ccgcaatctc cttcgcaatc tcctccatag
    18301 tcatagccgc aaaggactcc agctccttct ccgtcagacc gttctcctcc accagttcat
    18361 agaggaagca cgcctttcca taggaaattc catattgatt ggaaatctcc gtaatctcct
    18421 tcatatccgt agcctgctgg tcatagacca ccgcatttac cttgtgggct tccagagagc
    18481 tctcaatatc tgtcaccacg tcctgcctga gaacagaggc cttctctctg tcgtcgttgg
    18541 acacagtgac aagaatggcg ttatccagct cgtccagata gccgcaccga accatggaac
    18601 cgataatggc attcactccg atgttcaaat ccaccccgtc caggtccata tctgccagca
    18661 cttcggctcc gtcgtcgttt agcggctccg cctccagaat ctcatccttc ctgttcacag
    18721 aaatctcaat gctggggttt acatccagac caatcaccga ttccacccgc gtgttctgcc
    18781 agcgcacacc tccgccgtac agagccgcta tgcacagaca ggcggcggca gctgtgaccg
    18841 cgcggcgcat tctccggtac gtcttcaggt gccgcggcgg ctccatatat aaaagctgcg
    18901 gcgcgctcaa gtctatttga tcaagcacat tgggagtcag ggtttccacc gccgatttta
    18961 aatggctggc aatctcgtca ttattccatt tttcatgtcc atcggccaat gttatccctc
    19021 ctctctcaaa tgatttttta atttcttcat ggcccggtta tacttcgaca gcacagtggc
    19081 taaaggcatc cccaaatctg cggcgatctc tctgtgcttc agtcctgccg ccgtatgcag
    19141 cagcacaatc tggcgctcct cctccttcaa aatatggaga gccgcatgca gcaccacctt
    19201 gtcagccgca ttctctatct gaggacagaa ttcccctgtc tccatctccg aaagatcaga
    19261 aagtcctatg tcagactcat gcttctgatc gcggaatctc atatagcaga gattcctggc
    19321 tatggtaaac atccatgcca gaggctttcc ttgagcctgg tagcttcccg cagaggtcca
    19381 tatccgcaga tacgtctcct gcataatctc ctctgcgtcc tgaggattcc tcacaacaga
    19441 cagaataaag ctgtacatgg ttttatccgt attctgatat aactggcgaa acgcctcctg
    19501 atcgcccttc gcaatcttta acagaagctt ttcatcactg agccggccat agttttccgg
    19561 ctcttccatg acggcaaaca tccccattaa aaacatggat tttgtttcct ttctataata
    19621 gtttaatgca gcaaatccat ttcttattgc atctgccgca actttttttc attttggttt
    19681 tgttctgctt tttcttctgc tccctgcccc ttcggcccct ctactcatac cggacgcact
    19741 ttaaaaacag gccctccgcc ggcgctgtaa agcccgcctg ttctcgatcc aggctcttaa
    19801 atatctcctc agccgactcg ggcgtccgcc tgtgaagccc tgcctccagc aaggttccag
    19861 tgagaatcct gaccatattg tagaggaagc cgtccccggt aaaggaaagc tccactacgc
    19921 ttcccttctg ctctatctct atactctgca gggtacgcac ggttgatttt ttcgtccgct
    19981 tcagagagga aaaccccctg aagtcgtggg ttccctcaag cacaaccgcc atctgcctca
    20041 tggcgccgat atccagcttc tctccgagtc cgtacgcgta cttccgttca aacacattct
    20101 tttttcccgc cgtttcaacc cggtaaaggt atgtcttcga cactgcgctc aaacggctgt
    20161 gaaaacgctc cagaacctcc tctgccccga ttacggctat atcctccgga agatatcgat
    20221 tcaggtactc catgactgcc ttcggaagct cgtctgagcc gtgaaagctg tcaaagattt
    20281 ttaaaaattc cggatttttg ttgtttttca agcagttctc atccagatga acgtttgccg
    20341 tctggcccag agcatgaact cccgcatctg tgcggccgga gccgtgcacc aggatcggct
    20401 cccccgtcat tttctccaga atgctctcca gctttccctg aatggtgttc tgactgtttc
    20461 cctgcttctg ccatcccccg taccggcttc cgtcgtactg aaggattaat ttgatatttc
    20521 tatacactga atcattctcc catttatttt attctattcg tttgacgcgg cgcaaagctg
    20581 cggcggccag aaagaaaaaa acagttccag ccgcagcccc tcccatatcc agccacacgt
    20641 cgctgatctg tccggaacgg cccggcgtaa acagctgaag cgtctcgtct atcagcggaa
    20701 ccgccgccgt cagacacagc tgtcccagaa ctcttccctc tcttttgagt cctgtgccgt
    20761 tcaggctctg ggtcagaagc atgcccagga taaaatactc cccaaaatga gcgcattttc
    20821 tgaccacgtg ctctgtaatc cagggcgcgg caagtccaag ctctcccagc acaccgtgaa
    20881 tcagcctgag aactgagctg ctctcctggg acgacagcgc cgccggagtc agggaattaa
    20941 aataaataaa cgctacatat aaaagcagcg ccgcgtgcca gcctatctgt ctcttcatat
    21001 cttaaatcac aatcattctc cctctgtttt cttaatgctt tattatagta caggagaagt
    21061 ggaaagtaaa gaagccttca aaagcgtctc tcagccggct tttcatcgtc agccgtcttt
    21121 ccgccaataa tagtttgaaa tttatacata tttgtattgt tttttctatc tttttatcca
    21181 ttcatattct ttgccaaaat ttttttctat ttttcccctc gtttcgtcct tttnnnnnnn
    21241 nnnccttttg acgaagcgca taaacaggcg gttaaacctg ctattattgt ctgtttatag
    21301 aggaaaaatt gtttcaaaaa aggtacaaaa aatcattttt cacctattga caattcaatt
    21361 tccggtgcta tactgagtgc attcaaaggg aacgtgcctt tgaatcacag cagaaattca
    21421 gcggatgcat tacgcctgct gctctgcaca ctaatcataa aagcaaacat aaaagtaagg
    21481 acaatactca cttgaaagga tggtaactat gtctgagaac gataagaagg atttaattca
    21541 cgaggtaaac gtagcgtctt ccctctatag ctttgataca gaaacaaaaa cagcggaggc
    21601 tgagcacaag catccggctg agggaactct ggagagagaa ctgaccgacg tttccctgct
    21661 ttacaacctg gagacaaaga ataaataaaa gcataggata taaaaagaga gggtaccgct
    21721 caagcgtctg atttgatgct ccggcaaggc ggaaaatctc ccccttatat cctgccgctt
    21781 ggtgtggtat agtaaagaaa aagggaagcc acagaagcgg cctgcccctt caaaaactaa
    21841 caagctgcgc cgttacaaac ggcaggccgt caactattcg cggtagttgg cggccatttt
    21901 cttttatcct tgaaaatctc ggataacaaa gaccaacaag ggcagcaatg aatataaaaa
    21961 actgaataga aaagggagct atgaaaaact gaaatctttt ttcacagttc cctgtatcta
    22021 aaattgaaat ctttttgcga aaacaaaatc ttcattggta agtaatacac acatatcatt
    22081 attcttatat tctaaaacat taattgtaat taaattatcc tctgtaataa gcggtgtgtc
    22141 tgaagcttgc aaatcaattt cataatattc ttggtattcc ccattattta atgaaaaagg
    22201 aattggttca aaattatcta
//
LOCUS       DBMDUW010000040        21626 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1538_length_21626_cov_3.094262, whole genome shotgun sequence.
ACCESSION   DBMDUW010000040 DBMDUW010000000
VERSION     DBMDUW010000040.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 21626)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 21626)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21626
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1538_length_21626_cov_3.094262"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..1053
                     /locus_tag="ACZPCR_08385"
     CDS             <1..1053
                     /locus_tag="ACZPCR_08385"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: protein motif:HMM:NF012772.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA];
                     GO_function: GO:0071111 - cyclic-guanylate-specific
                     phosphodiesterase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HIR1230928.1"
                     /translation="LYRMEKDKMGVILENGSAEECMELYRAIQKTLKNLREWRQNKVT
                     VGISGGCAMYPADGVTVDELCRYADYALQYAKSHGKNRLEIFSKQILEGKKRSLSLLY
                     SLQKAVIQDYEGFSLYYQPQVDARTCRITGVEALLRWKDETGHPVSPAEFIPVMEENG
                     MIIPVGMWVMRTALEAGRLWVKEDPLFTVSVNVSALQILEEDFTAVLKQTVEEKEFPY
                     QNLIIELTESCMAKNLCMFEERFEELRALGIRVAMDDFGTGYSSLELLKTAPVDIVKI
                     DRGFVRNILNSTFDAAFISFVVAICHDAGIKVCLEGVETAVEYEFLKERDLDSFQGYC
                     FGRPVPENEIVLQKLV"
     gene            1187..2332
                     /locus_tag="ACZPCR_08390"
     CDS             1187..2332
                     /locus_tag="ACZPCR_08390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CobW family GTP-binding protein"
                     /protein_id="HIR1230929.1"
                     /translation="MTKIDIISGFLGAGKTTFIKRLIGEAISGEKVVLIENEFGEIGI
                     DGGFLKDAGIEIREMNSGCICCSLVGDFGKSLSEVLTKYAPDRVIIEPSGVGKLSDVM
                     KAVRDVASEIEVELNSAVTVADAGKVRMYMKNFGEFFNNQIENAGTIVLSRTDIADPK
                     KVQKAVEMIREKNQRAVIVTTPISQLSGSQLLEIIEKKDDMMEDLLKEARDHAHDHGH
                     HDHHHEHGEECGCGHDHHDHAHHDHDHHHEHGEECGCGHDHHDHAHHDHDHHHEHGEG
                     CTCGCHDHHHHHADEVFASWGRENVTGVGREKLEEILDELAYGTKYGEVLRAKGMIPA
                     PDGTWLHFDLVPEQVEIREGSADYTGKVCVIGADLDEKALEEAFSAR"
     gene            2352..3287
                     /locus_tag="ACZPCR_08395"
     CDS             2352..3287
                     /locus_tag="ACZPCR_08395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003509251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family putative permease subunit"
                     /protein_id="HIR1230930.1"
                     /translation="MQEERMPLFLINGFLEAGKTEFIKFTMEQEYFKTEGKTLLIVCE
                     EGEEEYEEEFLKENRTEAVYVDDLSELTPEYLSDLELLHNPERVIMEWNGMWNLEELK
                     LPADWDLYQQITIVDGSTFDLYLNNMKPLIGVMVRNSEMIIMNRCDEAEDLDSYRRIL
                     KGMNPQVDIIFEDEEGQIEEVTEADLPYDVNAEVIEVSPEAYGIWYIDMLDKPDRYRG
                     KTVEFTAMVLKTPDFPKNYFVPGRMAMTCCEADMTFLGFMCKAKNARLLETKQWVKVK
                     ARVEYEYSPEYEGDGPMLYADYVEQAEPIQEIVQF"
     gene            complement(3413..4852)
                     /locus_tag="ACZPCR_08400"
     CDS             complement(3413..4852)
                     /locus_tag="ACZPCR_08400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006779363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HIR1230931.1"
                     /translation="MNQYSRRRGWSRRRRGRTRNNLPLILSGAVLALILLAGGIFFFK
                     NNGGLPTLLPASPSNAPGGQASETPEETEPLTEKQELQNLLDEAKRLAAGYDYDGAIA
                     LLTGNEKFKDTKEAAAAAAEYEEIKSTLVRVDPSKVTHVFFHSLIMDTSKAFDGDRKQ
                     NGYNQMMTTKDEFEKILQSMYDRGFVLVRLHDIAYETTDENGNPVFKAGDIMLPPGKQ
                     AFVMSQDDVCYYEYMDGDGFASRIVVGEDGKPVCEMKMDDGSISVGAYDLVPLLDEFI
                     EEHPDFSYRGAKAVLAFTGYNGILGYRTAASYGTAEYQAEHPDFNYEEEKAQAAKVAQ
                     ALKDDGYELASHSWGHRDMGAISMEDFVTDTNKWDTEVAPLIGGTDIILFPFGSDISD
                     WRPYKDDNERFQYLKSKGFRYFCNVDSSQYYVQIGTDHMRQGRRNLDGYRMYYDLPES
                     NPTKTHLDDLFNVEEVFDRSRPTPVPPMG"
     gene            5092..6306
                     /locus_tag="ACZPCR_08405"
     CDS             5092..6306
                     /locus_tag="ACZPCR_08405"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007882833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HIR1230932.1"
                     /translation="MKRILAFLTAVVLTAVIPAQEIYAHSPGLAVEVAAAAESNAGDG
                     PVIQAPSAILMEASTGTVIYEKNADEARNPASVTKIMTLLLTFDALKAGKIKLTDQVV
                     TSAHAKSMGGSQVFLEEGEVQTVETLIKCIVIASGNDASVAMAEHIAGDEASFVKMMN
                     ERARGLGMEHANFEDCCGLTDSSTHAMSARDIALMSRELITKYPEIFQYSTIWMENIT
                     HITKQGTKEFGLSNTNKLLKMATSFETTGLKTGSTSTAKYCLSATAKKDGVEMIAVVL
                     AAPDYKARFADAVTLLNYGYANCRLYTDKEEGEIPEIHVAGGVRDTVKARLNGTFSYL
                     STTGEDFSGIEKEWIFETDLEAPVHEGDIVGHLSYRLGGKEIGQTDIVAAEEIEKAGF
                     LDALKKVIAMVL"
     gene            6449..7261
                     /locus_tag="ACZPCR_08410"
     CDS             6449..7261
                     /locus_tag="ACZPCR_08410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008395006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative hydro-lyase"
                     /protein_id="HIR1230933.1"
                     /translation="MADYSKMKPGEVRELIRKGEITIPTAGMCGGYAQANLVILPKTY
                     ADDFREFARKNPKPCPILEIMEGSPEVHDMGEGANLVTDIPKYFIYKNGVKVDEVTDA
                     SAYWEDDFVGFLIGCSFSFEEALLKEGIDVRHISMGCNVPMYKSNIQCQPAGVFEGPT
                     VVSMRPMTPENAKKAYEITERYPNVHGCPVHMGDPAQIGIKDIMKPDYGDPVEIREGE
                     IPVFWACGVTPQAAVENAKPPIVITHAPGHMFITDIPNAELNDFLEAKKQGK"
     gene            complement(7362..8363)
                     /locus_tag="ACZPCR_08415"
     CDS             complement(7362..8363)
                     /locus_tag="ACZPCR_08415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015515348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIR1230934.1"
                     /translation="MKLSAVKGALSILLAASVLGGCSQNPDGLTPVTLNEVAHSIFYA
                     PQYAAIELGYFEEEGIDLALVNGKGADKVMTALISGDADIGFMGSESSVYVYQEGAED
                     YAVNFAQLTQRAGNFLVSRTPEPDFSWERLRGKTVLGGRENGMPEMIFEFILKKNGLD
                     PKTDLSIDKSIDFGLTAAAFSGNNADYTVEFEPHATALEQDQKGYVVASLGVDSGYVP
                     YTAYCAKKSFLSEHPEAVQSFTNAIQKGLSYVNSHSAEEIASVISPQFPETDVETIAA
                     IVSRYKDQDTWKKDTVFEKESFDLLQNILEEAGALNMRVPYEDLVTTEFSEAAKDVL"
     gene            8613..8927
                     /locus_tag="ACZPCR_08420"
     CDS             8613..8927
                     /locus_tag="ACZPCR_08420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007860127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YerC/YecD family TrpR-related protein"
                     /protein_id="HIR1230935.1"
                     /translation="MNKKIKTEAVDHLFQAILALKSPEECYSFFEDVCTVNEILSFSQ
                     RYEVAKMLREKRTYLEIADKTGASTATISRVNRSLNYGNDGYDMVFARLSGDAAPKKE
                     EE"
     gene            complement(8935..9585)
                     /locus_tag="ACZPCR_08425"
     CDS             complement(8935..9585)
                     /locus_tag="ACZPCR_08425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005610463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HIR1230936.1"
                     /translation="MKTNEQRLDDLMNFIDSLSRINTADIPDINLYMDQVTTFMDSHL
                     ASSLKPGEEKALTKTMINNYAKNNLLPPPEKKKYSRNHILLLTFIYYFKNVLSLRDIE
                     QLLSPISERCFAPRSRPELARLYEEIFSLEAEQRGRLVEDVKAKFASAMETFSDENFP
                     EFTEHADAGDREYLRLFAFVCELAFDVYLKKQMIELIAEDLRQEGNPNGKRKKDRK"
     gene            9721..10263
                     /locus_tag="ACZPCR_08430"
     CDS             9721..10263
                     /locus_tag="ACZPCR_08430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HIR1230937.1"
                     /translation="MEENFAEGKKEKEESCRPLIRDAGRYGLDGTSGQELREFNRLYK
                     RLDDLYHSLSLKMGMSDSTFIILYSIAELGDGCSQKEICEQVSISKQTINSSIRKLEG
                     SGVIRLEKRTRGRELHILLTEAGKQIIREKIYPIMEAEDRAFTHMPAEDRAEFLRLSR
                     LYVDEMICQTRPFLSEEEDA"
     gene            10260..12005
                     /locus_tag="ACZPCR_08435"
     CDS             10260..12005
                     /locus_tag="ACZPCR_08435"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007713532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1230938.1"
                     /translation="MKYILQFVKPYKGLTALALLFVTLDVLGALVIPTITADMINVGV
                     GSRNLNYIMEKGVLMLIVTVLSGASALMGSYFSARLSARIGRDMRNALYGKSLDFSIH
                     DFDQYGTGSMITRMLSDVSVIQQAVVWCVTMVLPVPALSLMGIAMAFSIDPSMGLVLG
                     GGVVFVVCLTVFISKKAASVFGRLQRFLDRMNVVMRENITGVRVIRAFNKETYEAKRM
                     KKSFEDYARAAVETNLLFAGLDSFSFFAISILAVAILWFGGNRIGAGTMEIGDITALT
                     EYTILILFYLMMAQMVIILLPRARVCLERIGEVLDREPEIRDEEEQQGEGLPERRTVE
                     EGEPVVSFENVSFRFADADEDTLSGLAFSCRRGETTAVIGGTGSGKSTIGRLMMRFYD
                     VSQGTVRICGRDVREMRQQDLRERVSYVPQKAWLFSGTIADNLKYGKPDASEEEMLHT
                     LSAAQADFVTELPEGLFSHTAQGGTNFSGGQKQRLAIARALMKKADLYIFDDSFSALD
                     FKTDSALRKALKEETKGAAVLIIAQRINTILNADQIVVLNEGKIAGIGTHRELMEGCS
                     VYQEIAKSQMRGGEE"
     gene            12005..13819
                     /locus_tag="ACZPCR_08440"
     CDS             12005..13819
                     /locus_tag="ACZPCR_08440"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1230939.1"
                     /translation="MDQEKRETGEELELEVPNHAVKTLKRMWDSSKDQHVRLYLVGAS
                     VVFYTLFSIVSPLYSAHLVDFIWNGVKEAEAAGTVFSFTWESGGAQLLIMFSLYFISW
                     LFYTAQNFLMAGFAERLNLRLREQLSRKLSRLPLSYFDGHQPGEILSRAVNDLDKVSE
                     ALQTGLLKLFTSVGLVAGSLLIMFFYHVPLTVVFLIFTGLSMVLTNFFTGKTLKTAAR
                     RQRALSRLTSCVEESMSGRMIIKAFNREEQSRQEIRQAAEQLAEEAGKADFLTQAINP
                     AIRFVNRVGQVLITVIGGKLLIDGVMTVGAIQAFLQYVYQAAEPLTEVSYMINSMQSA
                     LASVEHVYQMLDAEEISPEPEKPELVKGAEGSVVFEQVQFGYSPERLLMKNLSFTAKP
                     GQKIAIVGNTGAGKTTLINLLMRFYEVNGGRILLDGVDTAHMTRVDLRQNFGMVLQDT
                     WLFGGTIAENIAYGRPEASREEITAAAKAAHADFFIRTMPQGYDTVLDNEAETISAGQ
                     RQLLTIARVMLCSPPVLILDEATSSVDTRTEMAIGKAMQTLMKNRTSFVIAHRLSTIV
                     DADLILVMKDGDIIEQGNHRELLKAGGAYAELYNSQFA"
     gene            13933..14433
                     /locus_tag="ACZPCR_08445"
     CDS             13933..14433
                     /locus_tag="ACZPCR_08445"
                     /inference="COORDINATES: protein motif:HMM:NF012481.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HIR1230940.1"
                     /translation="MKIAIIYYSQTGHTREMGSVIAEGIERAGGEARLFSIEEPIDQE
                     YVDACDGVIIGTPTWVANTCWQIKKWFDVDSRSLNLAGKLGGVYATAHYAQGGADVAL
                     LTMIGHMLVKGMVLYSGGASLGKPFIHLGPVALDSVGTHFEDCREDFRIYGERFAKKA
                     GELFDR"
     gene            14677..17220
                     /locus_tag="ACZPCR_08450"
     CDS             14677..17220
                     /locus_tag="ACZPCR_08450"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HIR1230941.1"
                     /translation="MDNKFELLNPKQKEAVFHTEGPLLVLAGAGSGKTRVLTHRIAYL
                     IEEKDVNPWNILAITFTNKAAAEMRERVDKIVGFGAESIWVSTFHSSCVRILRRHIDR
                     LGYETSFTIYDTDDQRTLMKQIFKRLQVDTKQFKERSVLSRISSFKNDMIAPQEALQN
                     AGGDFREKKVAELYVEYQKELKKNNALDFDDLLLKTVELFEQENDVLEYYQNRFRYIM
                     VDEYQDTNRVQFKLVDQLAGKYRNICVVGDDDQSIYKFRGADIENILSFESAFPGAHV
                     VKLEQNYRSTQNILSAANEVIRHNRGRKDKTLWTSNGEGDQVKLAQFDTAYEEADYIV
                     KDILTETEKENRPFSDFAVLYRTNAQSRLLEEKCILYSVPYRLVGGVNFYQRKEIKDI
                     LSYLKTIANGQDDLAVQRIVNVPKRGIGATSMGRIIAFASAGGMSFYDALLRARAVPS
                     IGKAADKIAGFTDQIEDFKARLSELSIKDLIKEILEKTGYRKEIEEEGEVESETRLQN
                     IEELINKAAAYWEGAEEPTLGGFLEEVALVAEVDNMNESENRVVLMTLHSAKGLEFPY
                     VYLSGMEDGLFPSSMSILSDDTDAVEEERRLCYVGITRARERLTMTAARQRMTNGETR
                     FSKLSRFVEEIPPMLLDRQNQKSMFARGGSWAEGQESGKRSGNSLGEGLHFADDFDDS
                     GLPWGDDFEMESEERGAFGRGSSRREDSSSWAGNSSWGGSSFGGGSFGGGGSSFGGAS
                     VSGRDWDRSTEGWTAPKRSSGISAFGQKPNAYASKTASTAPSFGKAFTVQKAERLDYG
                     EGDRVRHMKFGEGTVTAIADGGKDYEVTVDFDRAGVKKMFASFAKLKKV"
     gene            17353..17658
                     /locus_tag="ACZPCR_08455"
     CDS             17353..17658
                     /locus_tag="ACZPCR_08455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007710446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HIR1230942.1"
                     /translation="MNKFDMMGKDAFNRVEEIMNATKLNEFLHRKEEEEKKKTCVLWI
                     LAIIGVVAAVAAIAYGVYRFFTPDYLEDFEDDFEDDFDDDFFDEEEAKAVEKEQDQE"
     gene            17772..19181
                     /gene="rlmD"
                     /locus_tag="ACZPCR_08460"
     CDS             17772..19181
                     /gene="rlmD"
                     /locus_tag="ACZPCR_08460"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0000154 - rRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HIR1230943.1"
                     /translation="MKKGEIYEGIVENMDFPNKGNIYIEGERVIVKNALPGQKVRFLV
                     NKRRKGKCEGRLLSVEKSSPLERTEHPCPHFGICGGCLYQTIPYEEQLKIKERQVRDI
                     LTPVLGEPEEGNWIFEGIMGSPISERYRNKMEFSFGDEVKDGPLALGMHKRGSFYDVV
                     TVGECRIINEDFTKILLCTKEFFEEKQIPFYKKMQKTGYLRHLLVRRAVKTGEILIDL
                     ITTTQTETLKTESWNSGEEELLAQWRDQLLALSLEGTMAGILHTKNDTLADAVKDEGT
                     EILFGQDFFYEELLGLKFRISPFSFFQTNSLGAEVLYEKTREYVGGVDGKVVFDLYSG
                     TGTIAQILAPVAEKVVGVEIVEEAVEAAKVNAGLNGLSNCEFIAGDVLKVVGELKDKP
                     DFIVLDPPRDGIHPKAIEKIIDFGVDRMVYVSCKPTSLARDLEILTARGYQAEKVCCV
                     DMFPATGNCETVCLLTRIK"
     gene            complement(19255..19446)
                     /locus_tag="ACZPCR_08465"
     CDS             complement(19255..19446)
                     /locus_tag="ACZPCR_08465"
                     /inference="COORDINATES: protein motif:HMM:NF012798.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HIR1230944.1"
                     /translation="MAFDYHSLRHTHATLLIENGADIKDVQARLGHADISTTLQIYIH
                     ATDAMAAKSVDIFEHTVNL"
     gene            19429..19659
                     /locus_tag="ACZPCR_08470"
     CDS             19429..19659
                     /locus_tag="ACZPCR_08470"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230945.1"
                     /translation="MVVERHFEFMVDNPGAVLGVSQSEFINRLLLFDDTIRKYQKMLD
                     SSGKKKYSDDVEAHLAALEQLGKDYGIWYETR"
     gene            19646..19783
                     /locus_tag="ACZPCR_08475"
     CDS             19646..19783
                     /locus_tag="ACZPCR_08475"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230946.1"
                     /translation="MKPGDKYYDGPIVDDGRTLEELERDIEAEKEKMKHIKWDPSMLE
                     E"
     gene            20405..20941
                     /locus_tag="ACZPCR_08480"
     CDS             20405..20941
                     /locus_tag="ACZPCR_08480"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230947.1"
                     /translation="MKRTNHIGNSGRFVLLAAVLAAVVCMAAFVYFRSDSMSGNDVVM
                     GAEYDIKKVLYAVTVGDEISTEPPAQYCVSADARLYDKQAEDGEWNLLGELSSYALTN
                     DELYGYMPAEELRRKVKIQPITASYILRVKEDSFYLVFQTKDGKTYLAYGWEDAKERG
                     QTGLGDTRLRRLYQLERR"
     gene            complement(20952..21167)
                     /locus_tag="ACZPCR_08485"
     CDS             complement(20952..21167)
                     /locus_tag="ACZPCR_08485"
                     /inference="COORDINATES: protein motif:HMM:NF024945.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1230948.1"
                     /translation="MNDEEIFKAVQLLEIYYDEEGSISRAADKLFIHKNTLQNRLKQI
                     QARTGYDPRSIRHSSLFYNALHFYREL"
     gene            complement(21278..>21626)
                     /locus_tag="ACZPCR_08490"
     CDS             complement(21278..>21626)
                     /locus_tag="ACZPCR_08490"
                     /inference="COORDINATES: protein motif:HMM:NF017466.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sugar diacid recognition domain-containing
                     protein"
                     /protein_id="HIR1230949.1"
                     /translation="NGIIIASTDESRIGTYHAGAKKLISEGLDELIINNEEGYEGSLP
                     GINYPLIVNGELIGVVGVTGNDAATLSCAKIIKRMTELLIQELSMKEKQEMEIIFSPA
                     GPVRRLKKPFTPA"
BASE COUNT         5916 a         4411 c         6058 g         5241 t
ORIGIN      
        1 ttatatcgta tggaaaaaga taaaatgggt gtgattcttg aaaatggttc tgcagaggaa
       61 tgtatggaat tgtacagagc tatccaaaag actctgaaaa atctgaggga gtggcgccag
      121 aataaggtga cagtaggaat ttcaggcggc tgcgccatgt atcccgcaga cggggtgact
      181 gtagatgaac tgtgccgtta tgcagattac gcactccagt atgcgaaatc tcatggcaag
      241 aaccgcctgg aaatattttc taagcagatt ttagaaggga aaaagcgttc gttatcactt
      301 ctgtacagcc tgcagaaggc tgtcatacag gattatgaag gtttcagcct ttattatcag
      361 cctcaggtag atgccagaac ctgccggatc acaggtgtgg aagcgcttct ccgctggaaa
      421 gatgagaccg gacatcctgt ctcaccggca gagtttatcc ctgttatgga agaaaatgga
      481 atgattattc cagtgggaat gtgggtgatg cggactgctt tggaggctgg acgtctctgg
      541 gttaaagaag atccgttgtt tactgtaagc gtcaatgtat ctgccttaca gattttggaa
      601 gaagatttta cagctgtttt gaagcagact gtggaagaaa aagaatttcc ataccaaaat
      661 ttgattatcg agttgacaga gagctgcatg gcgaaaaatc tctgtatgtt tgaggagcgt
      721 tttgaggaac tgagggcgct cggaatcagg gtggctatgg acgattttgg aaccggctat
      781 tcttctttgg agcttttgaa gacagctcct gtagatattg taaagattga cagagggttc
      841 gtcagaaata ttttaaacag tacctttgac gcggcattta tctcatttgt ggtggctatc
      901 tgtcatgatg cgggaattaa agtatgcctg gaaggggtgg agacagctgt agagtatgaa
      961 tttttgaaag aaagggatct ggacagcttt cagggatact gttttggacg gccagtgccg
     1021 gagaatgaga ttgttttgca gaaactggtc taaaaacgga cagagctggc gggcagattg
     1081 actttaggga cattttgtgt caaaataata acgcagcttc agccgggatt gtccggcagc
     1141 cgcatcagaa actgcagtaa aatttcagaa aagaaggtag atagacatga caaagattga
     1201 tattatttct ggattcctgg gcgcaggaaa gaccacattt attaaacgcc tgattgggga
     1261 agcgatttct ggcgaaaagg tagttctgat tgagaatgaa tttggcgaga ttgggattga
     1321 cggaggattt ttaaaggatg caggcatcga gattcgggag atgaattcag gatgtatctg
     1381 ttgttctctg gtaggtgact ttggaaaatc gctgtctgag gttctcacaa agtatgctcc
     1441 ggatcgcgtg atcattgagc cttcaggcgt gggcaagctt tctgacgtga tgaaggcagt
     1501 cagagatgta gcttctgaga ttgaagtaga gttaaacagc gccgttactg tggcagacgc
     1561 aggaaaggtg cgtatgtata tgaagaattt cggcgagttt ttcaacaacc agattgaaaa
     1621 tgcagggact attgttctta gccgaacgga tattgcagat cctaaaaagg tgcagaaggc
     1681 agtggagatg atccgtgaaa agaatcagcg cgcagtgatt gtgactactc caatcagcca
     1741 gctgtcaggt tctcagctgc ttgagattat tgagaaaaag gatgatatga tggaggatct
     1801 gctgaaagag gcgagggatc acgcccatga tcatggccat cacgatcacc atcatgagca
     1861 cggcgaagag tgtggctgcg gccatgacca tcacgaccat gctcaccacg atcacgatca
     1921 tcaccatgag cacggcgaag agtgtggctg cggccatgac catcacgacc atgctcacca
     1981 cgatcacgat catcaccatg agcatggtga aggctgtact tgtggctgcc acgaccatca
     2041 tcaccaccat gcagatgagg tttttgcaag ctggggacgt gagaatgtga caggagtggg
     2101 aagagagaaa ctggaagaaa ttctggatga gctggcatat ggcacgaaat acggagaggt
     2161 tttgagagct aagggtatga taccagctcc agacggaaca tggcttcatt ttgacctggt
     2221 tccggagcag gtggaaatta gagagggatc tgccgactat actggaaagg tgtgcgtaat
     2281 cggagctgat ttagatgaga aagctctgga agaggctttc agcgccagat agcagacagg
     2341 aggaataaca gatgcaggaa gaacgtatgc cgctgttttt aattaacggc tttctggagg
     2401 ctggaaaaac agagtttatc aagtttacca tggagcagga gtattttaaa acagagggaa
     2461 aaacccttct cattgtctgc gaggaaggcg aggaggagta cgaggaagaa tttttaaagg
     2521 agaacaggac agaggctgtc tatgtagatg atttgtcaga gctgacgcca gagtacctgt
     2581 cagatctgga gcttctccat aatccggagc gggttattat ggagtggaac ggtatgtgga
     2641 atctggaaga actgaagctt ccggcagact gggatctgta ccagcagatc acaatagttg
     2701 acggttctac ctttgatcta tacctgaata acatgaagcc gctgataggc gttatggtga
     2761 gaaattcaga gatgattatt atgaaccgct gtgacgaagc agaggatctg gattcttaca
     2821 gaagaatttt aaaaggcatg aatccacagg tggacattat ctttgaggac gaggaagggc
     2881 agattgagga agtgacagaa gcagacctgc cttatgatgt taatgcagag gtgattgaag
     2941 tttccccgga ggcctatgga atctggtata ttgatatgct ggacaagccg gatcgctaca
     3001 gaggaaagac tgtggagttt acagctatgg tcttaaagac accggatttt ccgaagaatt
     3061 actttgtgcc gggacgtatg gccatgacat gctgtgaggc agatatgacc ttcttaggtt
     3121 ttatgtgcaa ggctaaaaat gcccggcttt tagagacaaa gcaatgggta aaggtaaagg
     3181 cccgcgtaga atatgagtac agtccagagt acgagggaga cggccctatg ctttacgccg
     3241 attatgtaga gcaggcggag cctatccagg agattgtaca gttttaaact tgagatttgg
     3301 tgaaggacac ttttagatag caaaaaagga gcgctgcctg tcatctggta tggatgacag
     3361 gcagcgctcc tttcttatga cataggaaac tgcgtcctaa tggaagtttc ttttagccca
     3421 taggcgggac aggagtcggc ctggagcggt cgaatacctc ttctacatta aacagatcat
     3481 ctaaatgcgt ttttgtagga ttagattccg gcagatcata gtacatccgg tagccgtcca
     3541 gattccggcg gccctggcgc atgtgatcgg taccgatctg cacataatac tgggaagaat
     3601 ctacattaca gaaatagcgg aatcccttag atttcaaata ttggaatcgc tcattgtcat
     3661 ccttatatgg acgccagtca ctgatatcac tgccgaaggg gaagaggata atatcggtgc
     3721 ctccgatgag aggtgctacc tctgtatccc acttattcgt atctgtgaca aaatcttcca
     3781 tggaaatagc ccccatatca cgatgccccc aactgtggct ggccagttcg tagccatcat
     3841 ccttcagagc ctgagcaact ttagcagcct gtgctttctc ctcctcatag ttgaaatcag
     3901 gatgttcggc ctgatactcc gctgtgccat aggaggcggc ggtacggtat ccaagaattc
     3961 cattgtagcc ggtgaaggct aaaactgcct tagctccgcg gtaggaaaag tcagggtgtt
     4021 cctcaataaa ctcatctaag agaggaacca gatcgtaagc gcctacagag atgctgccat
     4081 cgtccatctt catttcgcag acaggctttc cgtcttcccc tacaacaatg cgtgatgcaa
     4141 agccgtcgcc gtccatatat tcatagtagc acacatcatc ctgggacatg acaaaggcct
     4201 gttttccagg cggaagcata atatcccctg ctttaaatac tggatttcca ttttcgtctg
     4261 tggtttcata ggcaatgtca tgaagccgta caaggacgaa accacggtca tacatagact
     4321 ggagaatctt ctcaaattca tccttcgtgg tcatcatctg gttgtatccg ttctgcttcc
     4381 tgtctccgtc gaaagctttg gaagtgtcca tgatcagaga gtggaagaaa acatgagtta
     4441 ccttagaggg atcaacccgt accagagtgg atttgatttc ttcatattca gcggcagcgg
     4501 cagcggcttc cttcgtatcc ttaaacttct cgtttcctgt aaggagagcg attgctccgt
     4561 catagtcgta gcctgcagcc agacgcttcg cctcgtccag cagattctgg agctcctgct
     4621 tctctgtaag aggctccgtc tcctctggcg tctcggaggc ctgtcctcca ggcgcgttgg
     4681 agggagaagc gggaagaagg gtaggaaggc cgccattgtt cttaaagaag aaaataccgc
     4741 cggctaacag aatgagagcc agtacggctc ccgataaaat aaggggaagg ttattccggg
     4801 tgcgccccct gcgccgccgg ctccagcccc gtcttcgtga atactggttc atagtcatac
     4861 tcctttagat gttccggaaa cagctgtgag attacagtac agtttcagcc gtatatggaa
     4921 cattgttttt atcttattat aacatatttg aaagaaacgt gccattaagg tttattacga
     4981 attttaaaag tttttgtgat gctgcgagaa acaggcaaaa cagggaataa agagggaggt
     5041 tcgtttcata tgcttgtgaa agaagataag atgttcgttt gggggatatg tatgaaacga
     5101 atcctggctt ttctgactgc agtggttctg acagcagtga ttccggcaca ggagatttat
     5161 gcccatagtc cgggacttgc ggtggaggtt gcagcggcgg cagaatcaaa cgcaggggat
     5221 ggccctgtta tccaggcgcc aagcgctatt ttgatggagg cttctaccgg aactgtgatt
     5281 tacgagaaaa atgcagatga ggcgagaaat cctgccagcg tgacgaagat tatgacgctt
     5341 ctcctgacat ttgacgctct gaaagcggga aaaattaagc tgacggatca ggtggtgaca
     5401 agcgcccacg ctaaatctat gggaggttcc caggtattct tggaggaggg agaggttcag
     5461 accgtagaga cattgattaa gtgtattgtc atcgcttcgg gaaacgatgc ttctgtggct
     5521 atggcagagc atattgcagg ggacgaggcc tcttttgtca aaatgatgaa tgagagagcc
     5581 aggggacttg gcatggagca cgcgaatttt gaggactgct gtggtctgac cgattcttcc
     5641 actcacgcca tgtcagccag ggacattgct ctgatgagcc gggaactgat cacaaaatat
     5701 ccggagattt tccagtattc tactatctgg atggaaaata ttacccacat taccaagcag
     5761 ggcacgaagg aattcggcct gtctaatacg aataagcttt taaagatggc cacaagcttt
     5821 gagactacag ggttaaagac aggttctaca tctacggcaa aatactgtct gtcagccact
     5881 gcaaagaagg acggagtaga gatgattgca gtggttttag cggctccgga ctataaagcg
     5941 aggtttgcag atgcagtgac attactcaat tatggttatg ccaactgccg tctgtataca
     6001 gataaggagg aaggggaaat tccggaaatt catgtggcgg gaggtgtcag agacacggtg
     6061 aaggccaggc ttaacggaac tttttcttat ttaagcacaa caggagagga cttttccgga
     6121 atagaaaaag agtggatctt tgagaccgat ctggaggccc ctgtccacga gggggatatt
     6181 gtggggcatc tgtcgtaccg gctgggggga aaggagattg gacagactga catagtagcc
     6241 gcagaggaga tagaaaaggc aggatttctg gatgcgctga aaaaagtaat agcaatggtt
     6301 ctttaatttc cttctttaat tttatttgct ttattcttga cagaacagat ggtgttttgt
     6361 ataataaaac agagaaaaat aataaaaata tgtgaaaaat atacaaaaaa ctaaatgcgc
     6421 cagtgataaa aaacaggagg ggaaccatat ggcagactac agcaaaatga aaccgggaga
     6481 ggtcagagag ctgatccgga agggagagat taccattccc acagcgggaa tgtgcggcgg
     6541 ctacgcccag gcgaatctgg tcattcttcc taaaacatat gcagatgatt tcagggagtt
     6601 tgcgagaaag aatccaaagc cctgtccaat tctggaaatc atggagggaa gtcctgaggt
     6661 tcacgatatg ggagaggggg caaacctggt cacagatatt cccaaatatt tcatttataa
     6721 gaatggtgtg aaggtggacg aggtcacaga cgcttccgct tactgggaag atgactttgt
     6781 gggatttttg atcggctgca gcttttcctt tgaggaggcc ctgttaaagg agggcatcga
     6841 cgtgcgccac atttccatgg gctgcaacgt gccgatgtac aaatccaata tccagtgcca
     6901 gccagccggc gtgttcgagg gaccgacagt tgtcagtatg cgccctatga cgccggaaaa
     6961 tgccaaaaaa gcttatgaaa ttacagagag atatcccaat gtacatggct gtccagttca
     7021 tatgggggat ccggcgcaga ttggaattaa agatattatg aagccggatt acggtgatcc
     7081 ggtagaaatc agagagggcg agattcccgt attctgggcc tgcggcgtga cgcctcaggc
     7141 agccgttgag aacgcaaagc ctccgattgt tattacccac gcacctggtc acatgtttat
     7201 cacagatatt ccaaatgctg aattaaatga tttcctggaa gcgaagaagc aggggaaata
     7261 gactgcagaa aaaaacagag aataaaaaag ctgaaagaag gcggaggggc gaaagccctg
     7321 tccgccttcc ggctgttcct gcggcttttt gagaagccgt tttacaggac gtcttttgcc
     7381 gcttctgaaa actcggttgt caccagatcc tcatagggaa cgcgcatatt taaggcgccg
     7441 gcttcttcca gaatattctg gagcaggtca aagctctcct tctcaaaaac cgtatctttt
     7501 ttccaggtgt cctgatcctt ataacggctc acaatggcgg cgatggtctc cacatccgtc
     7561 tctgggaact gagggctgat cacagaggca atttcctccg ccgaatggga atttacatag
     7621 gaaagtccct tctgaatggc gtttgtgaag gactgaactg cctctgggtg ctcagagaga
     7681 aagcttttct ttgcacagta ggcggtgtag ggcacatagc cggagtctac gcccagggaa
     7741 gctaccacat agcccttctg atcctgctcc agagccgtgg cgtgcggctc aaattccact
     7801 gtgtagtcag cgttgtttcc tgaaaaagca gctgcagtga gaccaaagtc aatgcttttg
     7861 tcaatggaca aatctgtttt tggatccagc ccgtttttct tcagaataaa ttcgaaaatc
     7921 atttcgggca ttccgttttc acgtccgccc agaacggttt ttccccttaa ccgttcccag
     7981 ctgaaatcag gctccggtgt tctggacacc agaaaatttc cggctctctg ggtgagctgg
     8041 gcgaaattga cggcgtaatc ctccgctcct tcctgataga catagacgct ggattccgaa
     8101 cccataaaac caatgtcagc gtcccctgag atcagggcag tcattacctt gtcggcgcct
     8161 ttgccgttga caagagccag gtcaattccc tcctcctcaa aatatcccag ctcaatggca
     8221 gcatactggg gagcatagaa gatggagtgg gccacctcgt ttaaagtgac aggcgtaagg
     8281 ccgtccggat tctgggaaca gccgcccaga acagaggcag ccagaagaat ggagagagcc
     8341 cccttaacag cagataattt cataaaataa aagcctccag aggaaaattt gatactgtca
     8401 ttctatgcgg caggagggga gaaggtgaga aatgaagcct gtcttcttgt cttctggcag
     8461 cggacaggaa gcatagggca tccgccagcc tcgtttccaa ggctgaattg atataaatta
     8521 atagtttctt tatcttttta ctatggactt cagaacttta gtatgctaaa attagaaaca
     8581 ggaatcatat tgatagagaa ggagttgcac ctatgaataa aaagataaag acagaagcag
     8641 tggatcatct gttccaggcg attctggcgc tgaagagtcc ggaggaatgc tacagctttt
     8701 ttgaggatgt gtgtacggtc aatgaaattc tttccttttc acagcgctac gaggtagcaa
     8761 agatgcttcg ggaaaagagg acttatctgg aaattgcaga taagacagga gcttccacag
     8821 ctaccatcag ccgtgtcaat cgctctttga actatggaaa tgatggatat gacatggtgt
     8881 ttgcacgctt gagcggagat gcggctccga agaaagagga agagtaggac aggattattt
     8941 cctgtccttt tttcgtttcc cattaggatt cccttcctgc ctcaaatctt cggcaatcag
     9001 ttcaatcatc tgttttttca gatacacatc gaaggccagt tcgcatacga aagcgaacag
     9061 ccgtaaatat tccctgtctc ctgcgtctgc atgttctgta aattccggaa aattctcatc
     9121 tgaaaaggtc tccatggcag aggcaaattt cgcctttaca tcctctacca gacgccctct
     9181 ctgctccgcc tccagggaga agatctcctc gtacagccgg gccagctcag gccgggatct
     9241 gggggcaaag cagcgctcgg aaatagggga gagcagctgt tcaatatccc ggagggaaag
     9301 cacattttta aaataataga taaaggtcag aagcaaaatg tgatttctgg agtatttttt
     9361 cttttccgga gggggcagaa gattgttttt tgcataatta ttaatcatgg ttttggtaag
     9421 ggccttttcc tctccgggct ttaaagagga agccagatgg gagtccataa aggtagtcac
     9481 ctgatccatg tacaggttaa tatctggaat gtcggcggtg ttaatccgcg acagactgtc
     9541 aataaaattc atcagatcat cgagtctctg ttcgttcgtc ttcatagttt gtcacctcgt
     9601 agttatatta tatagtattc aatactagat gacaagataa aaaattttct tgacttaaat
     9661 ccgatttcgg actaaaataa ggaaagtaag tccgaaatca tactaaacgg gaggaatttt
     9721 atggaagaga actttgcgga agggaaaaaa gagaaggaag aaagctgcag accgttgatc
     9781 cgggatgctg gacggtatgg cctggatgga acatcggggc aggagcttcg ggaatttaac
     9841 cgcctttaca agagactgga tgacctgtac cacagtctgt ctctgaaaat gggaatgtca
     9901 gacagcacct ttatcattct ttacagcatt gcggagctgg gggacggttg ttcccaaaaa
     9961 gagatctgcg aacaggtgtc gatcagcaag cagacgatta attcctctat ccggaagctg
    10021 gagggaagcg gcgtcatccg cctggagaag agaaccagag gcagggagct gcacattctc
    10081 ttaactgagg ccggaaaaca gatcataagg gagaagattt atcccattat ggaggcggag
    10141 gatcgggctt ttactcatat gccggcagaa gacagggcag aatttctgcg gctgagccgt
    10201 ctgtacgtag acgagatgat ttgtcagacg agaccgttct tgtctgaaga ggaggatgca
    10261 tgaaatatat tttgcagttt gtcaagccct acaaagggct gacggccctg gcgcttctgt
    10321 ttgtaacgct ggatgtgctg ggagctttgg ttatccccac aatcacggcc gatatgatca
    10381 atgtgggagt ggggagcaga aatctgaatt acattatgga aaagggcgtc ctgatgctga
    10441 tagtgaccgt gctgtcggga gccagcgccc tgatgggcag ctatttttcg gccaggctgt
    10501 cggccaggat tggacgggat atgagaaacg ccctgtacgg gaaatcgctg gatttttcca
    10561 ttcacgattt tgaccagtac ggaacgggct ctatgattac aagaatgtta agcgacgtat
    10621 cggtgattca gcaggctgtg gtctggtgcg tgacgatggt gctgccggtt cctgcattgt
    10681 ctctgatggg aattgccatg gcgttttcta tcgatccgtc catggggctg gtgttaggcg
    10741 gcggagtcgt atttgtcgtg tgccttacag tgtttatcag caaaaaggcc gcctctgtat
    10801 ttggacggct gcagcgtttt ttagacagga tgaacgtggt gatgcgggaa aatattaccg
    10861 gcgtccgtgt aatcagggcc tttaataagg agacgtatga ggcaaagcgt atgaagaagt
    10921 cttttgagga ttatgccaga gcggcggtgg agacgaatct tttgttcgcc ggcctggaca
    10981 gcttctcctt ttttgccatc agtattctgg cagtggcgat tctgtggttt ggaggcaacc
    11041 ggatcggagc cggaaccatg gaaatcggcg atatcacggc gctgacagag tatacgatat
    11101 tgattttgtt ttacctgatg atggcccaga tggttattat tctcctgccc agagcgagag
    11161 tgtgcctgga gcggattggg gaagtgctgg accgtgagcc ggagatcaga gacgaagaag
    11221 aacagcaggg agaaggtctg ccggagagaa gaacggtgga agaaggcgaa ccagttgttt
    11281 cctttgaaaa tgtgtccttc cggtttgcag acgcagacga ggacacgctg agcggtctgg
    11341 ccttttcctg cagacggggg gagaccacgg ctgtcatagg gggaacggga agcggaaagt
    11401 ctaccattgg caggcttatg atgcggtttt atgatgtcag ccaggggacg gtgcggatct
    11461 gcggcaggga tgtgagagag atgaggcagc aggatctgcg ggagcgcgta tcttatgtgc
    11521 ctcaaaaggc gtggctgttt tccggaacca ttgccgacaa cttaaaatac ggaaagccgg
    11581 acgcttctga ggaggaaatg ctccacaccc tttctgcggc ccaggctgat ttcgtcacag
    11641 agcttccaga gggccttttc tctcacactg cccagggagg aaccaatttt tctggaggac
    11701 agaagcagcg cctggccatt gccagagctc tgatgaagaa ggcggatctc tacatttttg
    11761 acgacagttt ctctgccctg gactttaaga cagacagcgc cctgagaaag gctctgaagg
    11821 aggagacaaa aggagccgca gtgctgatta tcgcccagag aatcaatacg attttaaatg
    11881 cggatcagat tgttgtgctg aacgagggaa aaattgccgg aatcggaacc cacagggagc
    11941 tgatggaagg ctgcagcgtg taccaggaaa ttgcaaaatc acagatgaga ggaggggagg
    12001 aataatggat caggaaaaga gagagacggg agaagaactg gagctggagg ttccaaacca
    12061 tgccgtaaaa acattaaaaa gaatgtggga ttcttcgaaa gatcagcatg taaggctgta
    12121 tctggtggga gcttccgtag tgttttacac gctgttttcc attgtgtcgc ctctttacag
    12181 cgctcatctg gtagacttta tctggaacgg agtgaaggag gcagaggcgg cgggaactgt
    12241 attttccttt acatgggaat ctggaggcgc gcagcttctt atcatgtttt ccctctattt
    12301 tatcagctgg ctgttctaca cagcgcagaa ttttctcatg gcaggttttg cggagaggct
    12361 gaatttaagg ctgagggagc agctgagccg taagctttcc aggcttcctc tgtcctactt
    12421 tgacggccat cagccgggag agattttaag ccgggcagtg aacgacctgg ataaggtgtc
    12481 ggaggcgctg cagacaggac tgctaaagct gtttacatca gtgggactgg tggcaggctc
    12541 tcttctcatc atgtttttct accatgtgcc cctgacggtt gtgtttctga tttttacggg
    12601 actttccatg gttctgacaa atttctttac aggaaagacg ttaaagactg cggccagacg
    12661 ccagagggcc ttgagcaggc tgaccagctg cgtggaggag agcatgagcg gccgcatgat
    12721 tatcaaggcg tttaaccggg aagagcagag ccgtcaggaa atccgccagg cggcggagca
    12781 gctggcagag gaagccggaa aagccgattt tcttacccag gccatcaacc cggctattcg
    12841 gttcgtaaac agggtggggc aggtgctgat cacagtgata ggaggaaagc ttctcataga
    12901 cggagtgatg acagtgggag ccattcaggc ctttctgcag tatgtgtacc aagcggcgga
    12961 accactgaca gaggtttcct atatgatcaa ttccatgcag tctgcgctgg cttctgtgga
    13021 gcatgtgtac cagatgttag acgcggagga gataagccct gagcctgaaa agccagaact
    13081 tgtgaaggga gcagagggaa gcgtagtctt tgagcaggta cagttcggat actctccgga
    13141 acgccttctc atgaaaaacc tgagctttac ggcgaaaccg gggcagaaga ttgccattgt
    13201 gggaaatacg ggagctggaa aaacaacgct gatcaatctt ttgatgcggt tttacgaagt
    13261 aaacggagga cggattcttc tggacggggt ggatacggct catatgacaa gagtggatct
    13321 caggcagaat ttcggtatgg tgcttcagga cacctggctg tttggaggaa ccattgcaga
    13381 aaatattgcc tatggcaggc cggaggcctc cagagaggag attacagctg ccgctaaggc
    13441 agcccacgcc gactttttca tacggaccat gccgcagggc tacgacactg ttctggacaa
    13501 tgaggcggaa acgatctcag ccggtcagag acagctgctc accattgccc gggtcatgtt
    13561 atgcagtccg ccggtactga ttctggacga ggccacctcc agcgtggata ccagaacgga
    13621 gatggccatc ggaaaagcca tgcagacgct tatgaagaac aggaccagct ttgtgattgc
    13681 ccaccgcctg tccacgattg tggacgcgga tctgattctg gtgatgaagg atggagacat
    13741 tattgagcag ggaaaccaca gagagcttct gaaggcaggg ggcgcttacg cagagctgta
    13801 caacagccag tttgcgtaag ggaaggcggt aaaagataaa aaacggattg aaaaaacagg
    13861 gaagagtcca tgacagatac gctgcgcagg tgtataatag ctgtatactg ggacggaaaa
    13921 ggaggaatta tcatgaaaat tgcaattatt tattacagtc agacgggaca taccagagag
    13981 atgggctctg tgattgcaga aggaattgag agagccggcg gcgaggccag gctgttttcc
    14041 atcgaggagc cgatagacca ggaatacgtg gatgcctgcg acggcgtgat catcggaact
    14101 ccgacctggg tagccaatac ctgctggcag attaaaaagt ggtttgacgt ggacagccgc
    14161 tccctcaatc tggccggaaa gctgggaggc gtttacgcta ccgcccacta tgcccaggga
    14221 ggcgcagatg tggcgctcct taccatgatt ggccatatgc tggtaaaggg catggtgctt
    14281 tattccggcg gagcgtctct tggaaaaccg ttcattcatt taggaccggt agccctggat
    14341 tctgtgggaa cccactttga ggactgcagg gaggatttcc gaatctacgg cgagcggttt
    14401 gcaaagaaag ccggagaatt gtttgacaga tagatgaagt gtcagagcca gaggccaggc
    14461 acgctggctc tgaagacata cagatacata tagatataag aaataaagga acaggccgga
    14521 ggcccccgaa acaggaggtt tccggtctgc ttttatttgg tctgcagctt ccgcctcctg
    14581 tcctgctgaa acaaggatga cacaggaaag aaaatatatt ataatgggaa ggcggataaa
    14641 accgcagcac catgagacag gtttatagga gataatatgg ataataaatt tgaactgtta
    14701 aatccaaagc agaaggaggc ggtctttcac acggaggggc ctctgcttgt gctggccggg
    14761 gcaggttcgg gaaagaccag ggttctgacc caccggatcg catacctgat tgaagaaaaa
    14821 gacgtgaatc cttggaacat tctggccatt acctttacca acaaggcggc tgcagagatg
    14881 agggaacgcg tggacaagat tgtgggattc ggcgcggaga gcatctgggt gagcaccttc
    14941 cactcctcct gtgtgaggat cctcagacgc cacatcgacc gtctgggtta tgagaccagc
    15001 ttcacgattt atgatacaga cgatcagcgc accctgatga agcagatatt taagcgtctt
    15061 caggtggata cgaagcagtt taaggagaga agcgtcctta gccggatttc ttcttttaaa
    15121 aacgatatga ttgctccgca ggaggccctt cagaacgcgg gaggagactt cagggagaaa
    15181 aaggtggcgg agctctatgt ggaataccag aaagagctga aaaagaacaa tgcccttgat
    15241 tttgacgatc tgcttttaaa gacagtagag ctgttcgagc aggagaacga cgtgctggaa
    15301 tattaccaga accggttccg ctacattatg gtggacgagt accaggatac aaaccgggtg
    15361 cagtttaagc tggtggatca gttagccgga aaatacagaa acatctgcgt ggtaggagac
    15421 gacgatcagt ctatttacaa gttcagggga gctgatattg agaatatttt aagcttcgag
    15481 tcggcgtttc ccggggccca tgtggttaag ctggagcaga actaccgctc tacccagaat
    15541 attttaagtg ccgccaatga ggtgatccgc cacaaccggg gcagaaagga taagacgctg
    15601 tggacctcca acggggaagg cgaccaggtg aaactggctc agtttgacac cgcctatgag
    15661 gaggcggatt acatagtcaa ggatatctta acagagacgg agaaagaaaa caggccgttt
    15721 tccgattttg ccgtgctgta ccggaccaac gcccagtctc gtcttttgga ggaaaagtgc
    15781 attctctaca gcgtgcccta ccgcctggtg ggaggcgtca acttctacca gaggaaggaa
    15841 atcaaggata ttctttccta tttaaagacg attgccaacg gacaggacga tctggcggtt
    15901 cagcgaattg tcaatgtgcc gaagcggggg attggagcta cctccatggg aaggataatc
    15961 gcctttgcct ctgccggcgg aatgagcttt tacgatgccc ttttaagggc cagggcggtg
    16021 ccgtccatcg gaaaggcggc tgacaagatt gccggattta ccgatcagat tgaggatttt
    16081 aaagccaggc tttcagaact gagcatcaaa gacttgatca aggaaattct cgaaaaaaca
    16141 ggatacagga aggaaatcga ggaggaaggc gaggtggagt ccgagacaag actccagaat
    16201 attgaggagc tgatcaacaa ggcggccgcc tactgggaag gcgcggagga accgactctg
    16261 ggaggattcc tggaggaggt agctctggtg gcagaggtgg acaatatgaa cgaatcagag
    16321 aaccgggtgg ttttgatgac tcttcacagc gccaagggac tggaatttcc ctatgtttat
    16381 ttaagcggaa tggaggacgg actgttcccc agcagcatgt ccattctgtc agacgacacc
    16441 gacgcggtgg aggaggagcg ccgtctctgc tatgtgggaa ttaccagggc cagagagcgg
    16501 ctgaccatga cggcggccag acagagaatg acaaatggag agacccgctt ttccaaactg
    16561 agccgtttcg tggaggagat tcctcccatg cttttagaca ggcagaacca gaagtccatg
    16621 tttgcgagag gaggctcctg ggcggaaggc caggaaagcg gaaaacgctc tggaaacagc
    16681 ttgggagagg gactccattt tgcggacgat tttgacgaca gcggactgcc gtggggcgat
    16741 gactttgaga tggaaagcga agagagaggc gcttttggca gaggatcgtc ccgcagggag
    16801 gacagctctt cctgggccgg caattcttcc tggggaggca gttcctttgg cggcggatcc
    16861 ttcggagggg gaggaagctc ctttggcggc gcttctgtct ctggaagaga ctgggatcgt
    16921 tctacagagg ggtggacggc tccgaagcgt tcctcaggca tcagcgcttt tggccagaaa
    16981 cccaatgcct atgcgtctaa aaccgcttcc acggctcctt cctttggaaa ggcctttaca
    17041 gttcagaagg cagagcgcct ggattacgga gaaggcgacc gggtgcggca tatgaaattt
    17101 ggggaaggaa ccgttacggc cattgcagac ggcggcaaag attatgaggt gactgtggac
    17161 tttgacagag cgggcgtgaa aaaaatgttt gcgtcatttg ccaaattgaa gaaggtgtaa
    17221 tgtttcctgt ccaaagcttc gtatggatga attgtaacta aaaatctttt ttcgagataa
    17281 atatatagta aaaagagcgg gatgatggta taatatcatt agaaaaatct cagaaagaaa
    17341 ggacgtggaa cgatgaataa attcgatatg atgggcaagg acgcctttaa ccgtgtggaa
    17401 gagattatga acgccacaaa gctgaatgag ttcctccaca gaaaagagga ggaggagaag
    17461 aaaaagacct gcgtactctg gattttggca attatcggcg ttgtagccgc cgtagccgcc
    17521 attgcttacg gagtgtaccg tttctttacg ccggattatc tggaggattt tgaagacgac
    17581 tttgaggacg attttgacga cgacttcttc gatgaggagg aagctaaggc agtagagaag
    17641 gaacaggatc aggaataaag cagaggccgg agaccgattg gtttccggct tttctactag
    17701 tcaaacatat attttttgtg tatactgttg agagccaatg atgcgtacga tggaaaggaa
    17761 tgacaaagag aatgaaaaaa ggcgaaattt atgaaggaat cgttgaaaat atggattttc
    17821 caaataaagg aaatatttac atagagggag agcgcgttat tgtaaaaaac gctctgccgg
    17881 gacagaaggt gcgtttcctg gtaaataaga gaagaaaggg aaagtgcgag ggacgcctgc
    17941 tgtctgtgga gaagagctct ccgttagaga ggacagagca tccgtgtccc cattttggaa
    18001 tctgcggagg ctgtctgtac cagacgattc cctatgagga gcagctgaaa atcaaggaac
    18061 gccaggtgag agacattctg acgcctgtgc ttggagagcc tgaggaagga aactggatct
    18121 tcgagggaat tatgggaagc ccgatttctg agcggtacag aaacaaaatg gaattttcct
    18181 ttggagacga ggtaaaggat ggcccgctgg ctctgggaat gcataagagg ggcagctttt
    18241 acgatgtagt gacagtgggg gagtgccgga ttatcaacga ggattttacg aagattctgc
    18301 tctgcaccaa ggagtttttt gaggagaagc agattccgtt ttataaaaaa atgcagaaga
    18361 caggttatct gcgccacctt cttgtaagga gagcggtgaa gacaggagaa attctgattg
    18421 acctgattac tacgacgcag acagagacac tgaaaacaga gagctggaac agcggggagg
    18481 aggagctgct ggctcagtgg agagaccagc ttctggctct ttccttagag ggaaccatgg
    18541 ctggaattct ccacacaaag aacgataccc tggccgatgc agtgaaggac gagggaacgg
    18601 agatcctctt tggccaggat ttcttttatg aagagctgct gggactgaaa ttcaggattt
    18661 ccccattctc cttcttccag accaactctc tgggagccga ggtgctctat gagaagacga
    18721 gagagtatgt gggaggcgta gacggaaagg tggtgttcga cctttacagc ggaacaggca
    18781 ccatcgccca gattctggcc cctgtggcgg agaaagtagt aggcgtggag attgtggagg
    18841 aggccgtgga ggcggctaag gtaaacgcag ggctcaacgg cctgtcaaac tgcgaattta
    18901 tcgcaggcga tgtgctgaag gttgtgggcg aactgaagga caagcctgat tttattgtgc
    18961 tggatcctcc gagagacggc atccatccca aggccattga gaaaatcatc gatttcggcg
    19021 tggaccggat ggtgtacgtg tcctgcaagc ccaccagcct ggccagggac ctggagattc
    19081 tcacagcccg gggctatcag gcggagaagg tctgctgcgt agacatgttt ccagcgacgg
    19141 gaaactgtga gacggtgtgt ctcttaactc gcataaaata aggggttatg agagttaaga
    19201 gggtagaaaa acaggctgat gccaacgttt tgtcaacgct tttttcatcc gttgtcaaag
    19261 gttgacggta tgttcgaaga tatctacgct tttggctgcc attgcatctg tggcgtggat
    19321 ataaatttga agtgtggtgc tgatgtcagc gtggcctaag cgggcctgca cgtccttgat
    19381 atcagcgcca ttttctatta acagagtagc atgagtgtgg cggagggaat ggtagtcgaa
    19441 cgccattttg agttcatggt ggataaccct ggcgcagtat tgggagtatc ccaaagtgag
    19501 tttatcaaca ggctcctact ctttgatgat accattagaa agtatcaaaa aatgcttgat
    19561 tcttcaggga aaaagaagta ttctgatgat gtagaagcac atttagcagc attagagcag
    19621 ctgggaaagg attatggtat atggtatgaa accaggtgat aaatattatg atggcccaat
    19681 tgtagatgat ggaagaacat tggaagaact cgaaagagac attgaagcag aaaaagagaa
    19741 aatgaagcat attaaatggg atccaagtat gcttgaagag taaaagcatc agatatttgt
    19801 agtctggtgt ttttttgcac ctatttttat gatgctggcg aggaattgaa acgttttggt
    19861 atcaagaaag gcttgcccct gccacctgtg cgaagcaggc atttatcctt ctggaagaaa
    19921 ggcatgatcc atacccatac atcgaatgtc ggagcgaaac attacagatg atgaaatcca
    19981 aagctatatg aataatgaaa aagggatgtt tgttcagtgg aaaggagaaa gacaaacatt
    20041 ttatggaaga aagatgattt cgacgaggac acagtaaaag cattggaggt gatgataaaa
    20101 tatggctttc agtgcagatt tatgctatga ttctccgacg tgtttgaacc gaagtttcaa
    20161 aatatcttca acaaaggaac ttgcagatat tgcagaggca tgaaaaattt gcgcaaagtg
    20221 cccatgcagt gagttgtaaa ataacgcacg aatctgtatc gggcaaagga ggtttgatta
    20281 tatacatggc taagagccaa acttaaagaa aatatttgaa aatataaaag aagttttata
    20341 gtctgacttg agattttaaa aggatataag cagtaatggt taaaactaca gggggggttg
    20401 tagaatgaaa cggacaaatc atataggaaa cagcggccgt ttcgtattgt tagcagctgt
    20461 tctggcagct gttgtctgca tggcagcttt cgtttatttc aggagcgatt ctatgtctgg
    20521 gaatgatgtg gttatgggcg cggaatatga tataaaaaaa gtactttacg cagtgacggt
    20581 aggagatgaa atttccacag agccgcctgc acagtattgt gtgtctgcag acgcccgcct
    20641 ctatgataag caggcggaag acggggaatg gaatctgctg ggggagcttt ccagttatgc
    20701 cctgacaaac gatgaactgt atggctatat gccggcagag gagctgcgca ggaaggtgaa
    20761 gattcaaccg attacagctt cttatatttt aagagtcaaa gaggacagtt tttaccttgt
    20821 atttcagaca aaagacggaa aaacctacct tgcttacggg tgggaggacg ccaaagaaag
    20881 agggcagact ggcttgggtg atactagact gcgccgcttg taccagctgg aaagaagata
    20941 gcgctgtgtt ctcaaagctc cctgtaaaag tgcagcgcat tatagaacag agacgaatgg
    21001 cgtatggacc ggggatcgta cccggtcctg gcctggatct gcttcagacg gttctgcagg
    21061 gtgtttttgt ggatgaacag cttgtcagcc gcccggctga tagagccttc ctcatcgtaa
    21121 tagatttcaa gcagctgcac agccttgaaa atttcttcgt cattcatgcc tttaaaaatt
    21181 ttgtgaacat attctgattt tactgtttct gaaagctcgt cagtgaaaat ttccatattt
    21241 aagtcgtcgt aaaaacgcag atcatgcagg tgggttctca ggcaggcgtg aagggctttt
    21301 ttagcctgcg cacaggccct gcaggcgaga agataatttc catttcctgc ttttctttca
    21361 tagagagctc ctgaattaaa agctctgtca tgcgtttgat gattttggcg caggacaagg
    21421 ttgcggcgtc atttccggta acgcctacta cgccgatcag ctctccattc acaattaaag
    21481 gatagttaat tcctggaagg cttccctcat atccctcctc attattgata atcaattcgt
    21541 caagcccttc gctgatcagt ttcttagcgc cggcatgata agttcctatt ctggattcat
    21601 ctgtgctggc aataataata ccgttg
//
LOCUS       DBMDUW010000041        21561 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1541_length_21561_cov_3.784949, whole genome shotgun sequence.
ACCESSION   DBMDUW010000041 DBMDUW010000000
VERSION     DBMDUW010000041.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 21561)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 21561)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21561
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1541_length_21561_cov_3.784949"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            8..2089
                     /gene="ftsH"
                     /locus_tag="ACZPCR_08495"
     CDS             8..2089
                     /gene="ftsH"
                     /locus_tag="ACZPCR_08495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002578015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HIR1230950.1"
                     /translation="MITLMFTMLCVMVMNTWLNNANKENIPYSEFDQMLKNHEVESVT
                     LSGGRILITPNKNSSKYQSSKDRWGNLIGKEYYTVPINDPSFLEKLDEAGVATYEAKE
                     ADAGVEILLVILNWILPIAILFFFFNFMMRRMGGGGGGGIMGVGKSNAKVYVQKETGI
                     TFKDVAGEDEAKESLKEIVDFLHNPGKYTKIGAKLPKGALLVGPPGTGKTLLAKAVAG
                     EAKVPFFSLSGSDFVEMFVGVGASRVRDLFKQAQESAPCIIFIDEVDAIGKSRDSRLG
                     GNDEREQTLNQLLSEMDGFDSSKGLLVMAATNRPEILDPALLRPGRFDRRVIVDKPDL
                     KGRINILKVHSKDVKLDETVNFEEIALATSGAVGADLANMMNEAAITAVKHGRQAVSQ
                     KDLFEAVEVVLVGKEKKDRILSKEERRIVSYHEVGHALVNALQKDAEPVQKITIVPRT
                     MGALGYVMQVPEEEKYLNTKKEIHAMLVGFLAGRAAEEIVFDTVTTGASNDIEQATRI
                     ARAMVTQYGMSDKFGLIGLASREDQYLSGRTVLNCSDETAADIDKEVMMILKEAYEEA
                     KAMLQENRDALDAIAAFLIEKETITGKEFMKILREIKGIPEPEEESGQSGRLDLKEKT
                     EDPAGADSEETSSAVKENAVQDEAETSSEPEEPEQPEQQESEEVPEPARESKEQQPES
                     EEPEKEPDTQN"
     gene            complement(2210..3691)
                     /locus_tag="ACZPCR_08500"
     CDS             complement(2210..3691)
                     /locus_tag="ACZPCR_08500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008725146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HIR1230951.1"
                     /translation="MRTGFDNDKYLKMQSDHIRKRIGQFGDKLYLEFGGKLFDDYHAS
                     RVLPGFAPDSKLRMLLQLADQAEIVITINAADIEKNKVRSDLGITYDVDVLRLIQTYT
                     DKGLYVGSVVITHYAGQSSADLFKKKLENLGIKVYRHYIIEGYPSNISLIVSDEGYGK
                     NEYIETTKPLVIVTAPGPGSGKMATCLSQLYHENKRGIKAGYAKFETFPIWNIPLKHP
                     VNLAYEAATADLNDVNMIDPFHLEAYGVTTVNYNRDIEIFPVLNAIFEGIYGSCPYKS
                     PTDMGVNMVGNCISDDEVCCEASRQEIIRRYYQALSRVVKDQPGSKNEVYKIELLMKQ
                     AKIVTSMRSVVPAANELAAREGAPAAALELPDGSIVTGKTSNLLGASAALLLNAVKEL
                     GRIPHERHLISPASIEPIQKLKVDYLGSANPRLHTDEILIALSTCAASDEDAKRALEQ
                     LPKLKGCQVHTSVILSDVDIKTFKKLGIELTCEPVYEHKGIYH"
     gene            3895..4530
                     /locus_tag="ACZPCR_08505"
     CDS             3895..4530
                     /locus_tag="ACZPCR_08505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HIR1230952.1"
                     /translation="MDRIPKPGEFYRHFKNKMYQIVAVASHSETGEKLVIYQALYGDY
                     GIYARPLDNFLSPVDREKYPQAEQKFRFEKTEPGCGNEAEPEQGTREKTLVQSRRNCG
                     LAGRGVVSAERDGGWGFSPIEPVPDQPNPLLIEFLDAESTEEQLAVLRRMEGCVGKRE
                     LDSVCVYLDISTRYGSLEEQTEGIRRYLKLQMHYDASRLRRGKRDDSSCFI"
     gene            4518..6383
                     /gene="uvrC"
                     /locus_tag="ACZPCR_08510"
     CDS             4518..6383
                     /gene="uvrC"
                     /locus_tag="ACZPCR_08510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HIR1230953.1"
                     /translation="MFHIEEELKKLPAQPGVYIMHDEKDEIIYVGKAISLKNRVRQYF
                     QSSRNKTAKIEKMVSHIARFEYIITDSELEALVLECNLIKEHRPRYNTMLKDDKTYPY
                     IKVTVSEEYPRILFSRTMKKDKNKYFGPFTSSGAVKDTIDLLHRIYRIRTCTRNLPRD
                     IGKDRPCLYYHIKQCDAPCQGYISKEDYQKQIRGALDFLGGKYAPVTKALTDKMYEAS
                     EQMEFEKAAEYRDLIKSVNQIAQKQKITSQSMDDRDVIAMAKDERDVVVQVFFVRDGR
                     LIGREHFHVEAGTAESNGQILNGFVKQFYAGTPFIPHEIWCQEELEDADLIGRFLSER
                     RGQKVRILVPRKGEKERLVELAKKNARMVLAQDKEKIKREELRTTGAMNQIGGLIGLE
                     KVRRIEAYDISNISGFESVGSMIVYEDGRPKRNDYRKFRIRTVQGPDDYASMREVLTR
                     RFSHGLAEREEISAEGGQLEMGSFTRFPDLIMMDGGRGQVNIALEVLQKLQISIPVCG
                     MVKDDNHRTRGLYYRNEEIPIDRYSEGFKLITRIQDEAHRFAIEYHRSLRGREQVRSV
                     LDDIRGIGPARRKALMRHFKTIEAVRDAQVEELSAVPQMNQAAAEAVYHFFHAKE"
     gene            6460..7389
                     /gene="hprK"
                     /locus_tag="ACZPCR_08515"
     CDS             6460..7389
                     /gene="hprK"
                     /locus_tag="ACZPCR_08515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013271795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HIR1230954.1"
                     /translation="MYGVTIKELIKKMDLKNMTPELDTEKTVLVHPDVNRPALQLTGF
                     FDHFDKERVQIIGYVEQAYLNTLTLDRRRYIYDKLISSKIPCLLYSRGLEPDECVLEL
                     CNYYGVPCMISKKTTSDLMAEVIRWLNVKLAPMISIHGVLVDVFGEGVLIMGESGIGK
                     SEAALELIKRGHRLVSDDVVEIKRVSDDTLIGSAPDITRHFIELRGIGIIDVKTLFGV
                     ESVKDTQSIDMVIKLEEWDKDKEYDRLGMEDQYTEFLGNKVVCHSIPIRPGRNLAVIV
                     ESAAVNYRQKKMGYNAARELYNRVQANLAAKND"
     gene            7481..8455
                     /gene="murB"
                     /locus_tag="ACZPCR_08520"
     CDS             7481..8455
                     /gene="murB"
                     /locus_tag="ACZPCR_08520"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006772802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HIR1230955.1"
                     /translation="MDEFYRALCRAAGEEQVKRQESMALHTTFRTGGPAAFFASVKTE
                     EELRQTVGACREYQVPYYMLGNGSNLLVGSAGFPGVMIRLDGELKEWRILREEEDGRV
                     LLKAGAGLLLSKIGRAALEEGLTGFEFAAGIPGTLGGAAVMNAGAYGGEMKDILVSVR
                     VMTPDGQVEELPAGGLQLSYRHSCIPERGYAVLSAVMELKRGNKEEIRERMEDLAFRR
                     RDKQPLEYPSAGSTFKRPEGYFAGKLIEDAGLKGYSVGGAQVSEKHAGFVINRENASP
                     EEIRDLIEAVRTRVFETSGVRLEPEVKLLGFGPSAWGDTASADSKRSN"
     gene            8459..9340
                     /gene="rapZ"
                     /locus_tag="ACZPCR_08525"
     CDS             8459..9340
                     /gene="rapZ"
                     /locus_tag="ACZPCR_08525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006779921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HIR1230956.1"
                     /translation="MRLVIVTGMSGAGKTTALKMLEDMGFYCVDNLPIPLIGKFAELA
                     GSRRGEKSQAALGIDIRSGESLEELGAILKEWDESRFPYEILFLDAGDEVLIKRYKET
                     RRSHPLAGLDRLDRGIEKERRKLAFLKKRADYILDTSMLLTKELRIELEKIFISNEDY
                     RSLYVTVLSFGFKYGIPVDADLVFDVRFLPNPYYVDELKSHTGNEPEVQEFVMKGGLA
                     EEFLKKLSDMVLFLLPHYVEEGKNQLVIAIGCTGGKHRSVTVANRLYERLKAKEDIGV
                     KIEHRDIEKDSRRKQEV"
     gene            9342..10346
                     /gene="whiA"
                     /locus_tag="ACZPCR_08530"
     CDS             9342..10346
                     /gene="whiA"
                     /locus_tag="ACZPCR_08530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006779922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HIR1230957.1"
                     /translation="MSFSSHVKEELSRQVSPARHCQIAETAAILSLCGKVHITEDNQY
                     MIRIHTENVAVARKYFTLLKKAFNIRADVAIRRNAFLKKNRTYTVAVRRSRDAVRVLQ
                     AARLLGDDGDVCENMSVVKNLIIQNSCCRRAFVRGAFLAAGSLSDPEKFYHFEIVCSS
                     EEKAEQLREIIGTFSIEAKIVVRKKYYVVYIKEGSQIVEILNVMEAPLALMELENIRI
                     LKEMRNSVNRQVNCETANINKTVSAAVKQLQDIAYIRDTVGLDYLPESLAEIAQARLE
                     RPDATLKELGEILSPPVGKSGVNHRLRKISSIAESLRGQKSQQQELFLERNEEESYEK
                     "
     gene            10336..10590
                     /locus_tag="ACZPCR_08535"
     CDS             10336..10590
                     /locus_tag="ACZPCR_08535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006779923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HIR1230958.1"
                     /translation="MKSKEVTIELASGLEARPVAMLVQVASQYESRIYMEYANKKVNA
                     KSIMGMMSLVLPVGEKVVVTADGSDEDTAIASIEKYLSAE"
     gene            10748..14227
                     /locus_tag="ACZPCR_08540"
     CDS             10748..14227
                     /locus_tag="ACZPCR_08540"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002564618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HIR1230959.1"
                     /translation="MAFTHLHVHTEYSLLDASSKIKELVARAKALGMDSLAITDHGVM
                     YGVIDFYRAAREAGIRPVLGCEIYVCPGSRFDREIGVGEDKYYHLILLAENNEGYQNL
                     MKIVSAGFVEGFYYKPRVDYETLERYSRGLICLSACLAGEVQRNLSRGMYEEGKKAAL
                     RYQKIFGEGNFFLELQDHGIPMQKTVNQGLLRMSQDTGIPLVATNDCHYINREDEKSH
                     DILLCIQTGKKVADENRMRYEGGQYYVKSEEEMKNLFPYALEALENTHKIAMRCNVEI
                     EFGVTKIPQFDVPGGKTSWEYLNELCTSGFEKRYPEDDGSLRKRLDYELSVIQSMGYV
                     DYFLIVWDFIHFARSHDIMVGPGRGSAAGSIVSYSLGITDIDPIRYNLLFERFLNPER
                     VSMPDIDIDFCFERRQEVIDYVVQKYGRDRVVQIVTFGTLAAKGVVRDVGRVLDMPYA
                     KCDAVAKMIPGDLGMTLDKALKTPELREAYDSDPEIKYLIDMSRRLEGLPRHTSMHAA
                     GVVISRNKVDEYVPLSRAADGSITTQFTMTTLEELGLLKMDFLGLRTLTVIQNAVRQT
                     EKTHGIHIDLNQIDYNDRAVLESLGTGKNDGVFQLESGGMKSFMKELKPENLEDIIAG
                     ISLYRPGPMDFIPKYLKGKNDRSSITYDCPQLEPILSPTYGCIVYQEQVMQIVRNLAG
                     YTLGRSDLVRRAMSKKKAAVMEKERQNFVYGNPEEGVKGCIANGIDEKTANTIYDEMI
                     DFAKYAFNKSHAAAYAVVSYQTAYLKYYYPVEFMAALMTSVKDNVSKVSEYILTCRQM
                     GMKIMPPDINEGEGGFSVSSGAIRYGLSAIKSIGQSVVDEIVKERTARGPFTSLENFI
                     DRMSNKEVNKRTIESFIKSGALDSLPGTRKQKFLVSAALLDQKNKEKKNSMEGQMSLF
                     DFVEEEEKEQFQITFPDVGEYTKEELLAFEKEMLGVYVSGHPLEEYMDLWKKNVTAVS
                     SDFVVNEEEGTARVRDGAYVTIGGMITEKTVKTTRQNKMMAFITVEDLAGTVEVLIFP
                     RDYEKNRELLIEDEKVFVQGRVSIGDDPAGKLICERITPFSMVPRELWLKYPDKEAYF
                     SAEQELLDMLRLSEGSDRVVIYLEAERAKKVLPVNWSVSADSVLVERLSEKLGEKNVK
                     VVEKTIEKIGKMN"
     gene            14295..15269
                     /gene="pfkA"
                     /locus_tag="ACZPCR_08545"
     CDS             14295..15269
                     /gene="pfkA"
                     /locus_tag="ACZPCR_08545"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002564617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HIR1230960.1"
                     /translation="MAKEVKTIGVLTSGGDAPGMNAAIRAVVRTAINKGLKVKGIMRG
                     YAGLLQEEIVDMNGLSVADIIGRGGTVLYTARCPEFTTAEGQQKGAEICRRHGIDGLV
                     VIGGDGSFKGAGKLSALGINTVGLPGTIDLDIACTDYTIGFDTAVNTAMDAIDRVRDT
                     STSHERCSIIEVMGRNAGYIALWCGLANGAEDILLPERYDGNEQELISRIIENRKRGK
                     KHHIIINAEGIGHSASMARRIEAATGIETRATILGYMQRGGAPTCKDRVYASIMGAKA
                     VELLCAGKSNRVVAYKNGEYVDYDIQEALSMKKDIPEEQYKISKMLIR"
     gene            15363..15770
                     /locus_tag="ACZPCR_08550"
     CDS             15363..15770
                     /locus_tag="ACZPCR_08550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003508740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6145 family protein"
                     /protein_id="HIR1230961.1"
                     /translation="MAENVVLCGANSYVEKYYFNEEFSKLPEQVKEELQIMCVMFTED
                     VGGVLTLEFTPEGELQFKVACDETDYLFDEIGSALKIKQYQMEKRELLEALELYYRVF
                     ISGGEDAEKLKSLFLEEEKQEAHERKAGRIDES"
     gene            15760..16755
                     /gene="dusB"
                     /locus_tag="ACZPCR_08555"
     CDS             15760..16755
                     /gene="dusB"
                     /locus_tag="ACZPCR_08555"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015567897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HIR1230962.1"
                     /translation="MNHKTENRLQKKKLNIGGVELPSPVGLAPMAGVTDLPFRILCRE
                     QGCGLMCTEMVSAKALLYKNKNTKPLLETVPEEHPLAVQLFGSDPEIMSQMALQLEEG
                     PYDIIDINMGCPVPKIVNNGEGSALMKNPKLAGEIISAMVKKLKKPVTVKFRKGFNDQ
                     SVNAVEFAKMAEQSGAAAVTVHGRTREQFYSGKADWDIIRQVKEAVSIPVIGNGDIFT
                     PEDAARMMEETGCDGVMAARGAKGNPWLFHRINHYLETGEILPQPSLSEIRDMILRHA
                     RLQVEYKGEFIAMREMRKHVAWYTAGCPHSAALRNDINMVETLEGLIELVDKRLR"
     gene            16946..17428
                     /gene="greA"
                     /locus_tag="ACZPCR_08560"
     CDS             16946..17428
                     /gene="greA"
                     /locus_tag="ACZPCR_08560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008716565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0070063 - RNA polymerase binding [Evidence
                     IEA];
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HIR1230963.1"
                     /translation="MADKKHILTYTGLKQYEDELQDLKVNKRQEIAQKIKEAREQGDL
                     SENAEYDAAKDEQRDIEARIEQLEKLLKNAEVVVEEEIDLEKINIGCRVKVLDMEFDE
                     EMEFKIVGSTEANSLQNKISNESPVGHALLGKKAGDIVDVETQAGVIQYKVLEIQRVS
                     "
     gene            17453..19411
                     /gene="lysS"
                     /locus_tag="ACZPCR_08565"
     CDS             17453..19411
                     /gene="lysS"
                     /locus_tag="ACZPCR_08565"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003508743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HIR1230964.1"
                     /translation="MAEQQNNREEQELNHLLKVRREKLAELCESGRDPYKVTKYDVTA
                     HSAEVKVRYEELEGKEVSLAGRMMSKRVMGKASFCNLQDLQGNIQSYVARDEIGEEAY
                     KEFKKMDIGDIIGIRGIVFTTKTGEISIHAKSVELLSKSLQILPEKFHGLTNTDMRYR
                     QRYVDLIMNPEVKDTFIKRSQIVKEIRSFLDGRGFMEVETPVLVANAGGANARPFQTH
                     FNALDEDVNLRISLELYLKRLIVGGLERVYEIGRVFRNEGTDTKHNPEFTLLEIYQAF
                     TNYEGMMELTETMFREVARKVLGTLQVEYDGEVIDLEKPFARITMIDAVKQYSGVDFR
                     EIKTDQEAKAVAKEHHIEFENRHKKGDILNLFFEEYVEEKLVQPTFVTDHPVDISPLS
                     KRKPEDPEYTERFELYITRREFANAYSELNDPIDQRERFLAQEALKAAGDEEACSMDD
                     DFINALMIGMPPTGGLGIGIDRFVMLLTNSYAIRDVLLFPTMKSLDAKKGDNKAETAE
                     SKPNAFEAAAAGVSAPSVQLDLSKVKIEPLFEEFVDFDTFAKSDFRVVKVKECEAVKK
                     SKKLLKFVLDDGSGKDRTILSGIHEYYEPEELVGKTCVAITNLPPRPMMGIPSEGMLI
                     SAVYEYDGREGLNLLMLDDVIPAGAKLY"
     gene            complement(19669..20406)
                     /locus_tag="ACZPCR_08570"
     CDS             complement(19669..20406)
                     /locus_tag="ACZPCR_08570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230965.1"
                     /translation="MKNIGIVCEGPTDYIILQKVINLITNETNYYVQLQPEPDLTGQY
                     GNGWKGVWKWCCDNADIRKQLMKDITPRLDFLVVQMDGDVSRKEKSAHCSCPSVKCPY
                     KGIRNPLECDIKPEDRDACPVILPCQNHGAPITSYMEHLKGLLSTWLKEPDDTCIVIP
                     CDSTEAWIVAAYDNTAEVEFIKDPWESVIAKKATYHDIRISGKKKRTRIFEQFAPIVC
                     ENWEQVTNLCQSARDFEQSIYTLFHQT"
     gene            complement(20403..>21561)
                     /locus_tag="ACZPCR_08575"
     CDS             complement(20403..>21561)
                     /locus_tag="ACZPCR_08575"
                     /inference="COORDINATES: protein motif:HMM:NF024700.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HIR1230966.1"
                     /translation="NFKSLYSASFEPGKINVFVGANGSGKSTILEAIGLLSAAMTDRV
                     DSASLQRKGVRLSIPSLYKSNFKDLKRKKLTVDLSLEWENDCCSDQFRYDVHLTTPTD
                     TDYWRYHSEVFFQNDERIWGRSNASQQQANSYIGFFLIDDNQELTNGRKIAQHFSSYG
                     IFQPNTMTLRGTIPDPNQTTPIGLNGGRLAEAIKALIHEEDGELYFGSLYMDDILDMI
                     DWASDISVDAPKKSNINANIPTTRQIMEFTDRYMKENSRFTGYDASEGALYVLFMLAL
                     AMHPQGPSIFAVDSFDHALNPRLAKKMIQVFCEQIIQNNKHVFLTTHNPLVLDGLDLT
                     NDDIRLFAVDRDDNGHAQINRILVSQELINEGQSLSRLWINGRLGGVPTLL"
BASE COUNT         5895 a         4718 c         6269 g         4679 t
ORIGIN      
        1 agttgttatc attaccctga tgtttacgat gctttgcgtc atggttatga atacatggct
       61 gaataacgca aataaagaaa acattcccta cagcgagttc gatcagatgc tgaagaacca
      121 tgaagtagag tctgtgactc tcagcggcgg aaggattctt atcactccga ataaaaattc
      181 ctccaagtat cagtccagca aggacagatg gggaaatctc attggcaagg aatactatac
      241 cgtgccgatc aacgatccca gctttctgga gaagctggat gaggcgggag tagccaccta
      301 tgaggccaag gaggctgacg ccggggtgga gattcttctt gtgattttaa actggattct
      361 tccgattgca attctgttct tcttctttaa ctttatgatg agaagaatgg gcggaggcgg
      421 cggaggcgga atcatgggcg ttggaaagag caacgccaag gtttacgtcc agaaagagac
      481 aggaattacc tttaaggatg tagctggaga ggacgaagcc aaggaatcgc tgaaggagat
      541 tgtggatttc ctccacaacc cgggaaaata tacgaagatc ggcgccaagc tgccaaaggg
      601 agccctctta gtgggacctc cgggaaccgg taagacgctg ctggccaagg cggtagccgg
      661 agaggccaag gttccgtttt tctccctgtc cggatcggat tttgtggaga tgtttgtggg
      721 cgtgggagca tcccgtgtcc gcgatctgtt taagcaggct caggagtccg ctccctgcat
      781 tatctttatc gacgaggtgg acgccattgg aaagagccgt gattcccgtc tgggaggaaa
      841 cgatgagaga gagcagacgc tgaatcagct gctctcagag atggacggct ttgattcttc
      901 caagggtctg ctggtaatgg ctgccacaaa ccgtcctgag attctcgatc cggcgcttct
      961 gcgcccgggc cgttttgacc gccgggtgat tgtggataag ccggatttaa agggaagaat
     1021 taacatttta aaggttcact ccaaggatgt gaagctggat gagacggtaa attttgagga
     1081 gattgccctg gctacctccg gcgcagtggg cgcggatctg gccaacatga tgaacgaggc
     1141 ggccattacg gctgtcaaac acggccgcca ggctgtctct cagaaggacc tgttcgaggc
     1201 agtggaggtt gtgctggtag gcaaggagaa gaaggaccgg atcctcagca aggaggagag
     1261 acggattgtc tcctaccacg aggtaggcca tgcgctggtg aacgcgctcc aaaaggacgc
     1321 ggaaccagtc cagaaaatta cgattgtgcc ccgcaccatg ggcgctctgg gctatgtcat
     1381 gcaggtgcct gaggaggaga aatacttaaa taccaagaag gaaatccacg ctatgctggt
     1441 gggctttctg gcaggccgcg cggcggagga gattgtcttt gatacagtta cgacaggagc
     1501 ttccaacgat attgagcagg ctaccagaat tgccagagcc atggtgaccc agtacggcat
     1561 gtctgacaag ttcggcttaa tcggactggc ctccagggag gatcagtatc tcagcggaag
     1621 aacggtgctt aactgcagcg acgagacggc ggcagatatt gacaaagaag tgatgatgat
     1681 tctgaaggag gcctacgagg aagcgaaggc catgcttcag gaaaacaggg acgcgttaga
     1741 cgccatcgct gccttcctga ttgagaagga gaccatcaca ggcaaggaat ttatgaagat
     1801 tttgcgggag atcaagggaa ttccagagcc tgaggaggag agcggacaga gcggccgtct
     1861 ggatttgaaa gagaagacgg aagatcctgc aggcgcagac tcagaggaga cttcgagcgc
     1921 tgtgaaagag aacgccgttc aggacgaggc agagacatct tcagagccgg aagagcctga
     1981 acagccagaa cagcaggaat cagaagaagt acctgagccg gccagagaga gtaaggagca
     2041 gcagccggag tctgaggaac cggagaaaga gccggatact cagaattagg aacggcagga
     2101 ctgtctgaca gttagaaaac agcgtcagca cataaaagac atataaaaga aaacgcctgg
     2161 gcgaatcagt caatcaagtg attcgcctag gcgtttttta aatgggagcc tagtgataaa
     2221 ttcccttgtg ctcgtaaaca ggttcgcagg tcagctcaat ccccagcttt ttgaaggttt
     2281 taatgtctac gtcagacagg atcacagagg tgtgaacctg gcagcccttc agcttcggaa
     2341 gctgttctaa cgcccgcttg gcgtcctcgt cagaagcggc gcaggtggag agagcgatca
     2401 ggatctcgtc tgtgtggaga cgggggttgg cgcttcccag gtagtctacc tttaatttct
     2461 ggataggttc aatggacgcc ggggaaatca ggtggcgctc atgggggatt ctgccaagct
     2521 cttttactgc gtttaacaga agagcggctg aggctcccag gaggttgctg gtctttccag
     2581 tgacgataga gccgtccgga agctctaaag ctgccgcggg agctccctcc ctggcggcca
     2641 gctcattggc agccggcaca acagaacgca tgctggtgac gattttcgcc tgcttcatca
     2701 gaagttcaat tttatagacc tcatttttgg agccaggctg atccttgact acgcggctca
     2761 gggcctgata gtagcggcgg ataatttcct gtctggacgc ctcgcagcag acctcgtcgt
     2821 cgctgatgca gtttcctacc atatttacgc ccatatctgt gggggatttg taggggcagc
     2881 tgccgtagat tccctcaaag atagcgttga gaaccgggaa aatttcgatg tcgcggttgt
     2941 agttgactgt ggtgacgccg taagcctcca ggtggaaggg atcgatcatg ttgacgtcgt
     3001 tcagatcagc ggtagccgcc tcgtaggcca ggtttaccgg atgcttgagc ggaatattcc
     3061 agatagggaa ggtctcgaac ttggcgtagc cggccttgat gcctctttta ttttcatggt
     3121 acagctgaga taagcaggta gccatctttc cgctgcccgg gcctggagct gtgacaatga
     3181 ccagaggctt ggtcgtctcg atgtactcat tttttccgta tccctcgtcg ctgacaatga
     3241 gggaaatgtt ggaggggtat ccctcgatga tataatggcg gtaaacctta atacccagat
     3301 tttccagctt tttcttaaac agatccgcgc tggactggcc tgcgtagtgg gtgatcacga
     3361 cgctgcccac gtaaagtccc ttgtcggtat aggtctgaat gaggcggaga acgtctacgt
     3421 cgtaggtaat tcccagatca gagcggacct tgttcttctc aatatcagcc gcgttgatgg
     3481 tgatgacaat ctcagcctga tctgccagct gaaggagcat cctgagcttg ctgtctgggg
     3541 caaaaccggg gagcacccgg gaagcgtgat aatcgtcaaa cagctttccg ccgaattcca
     3601 gataaagctt gtcgccgaac tgtccgattc tcttgcggat gtgatcggac tgcattttca
     3661 gatacttgtc attatcgaat cctgttctca tagtttaccg tccttatcta ctctgtaatt
     3721 ttgtcgcatt aaattcctat ctattatgct acaaaaaata cgttttgagt agagggaaaa
     3781 tgatttttct taaaaaaaat ttccagaagc ccgccggaaa cagcattttc agtggcagag
     3841 acagggggaa aatggtatac tatcgtcagt atgcaaaggg acggaggaat aaaaatggac
     3901 agaattccaa aaccagggga attttacagg cactttaaaa ataaaatgta tcagattgtg
     3961 gcggttgcct cacattcaga gacaggggaa aagcttgtga tttaccaggc tttgtatggc
     4021 gattacggaa tttacgcccg cccgctggac aactttttaa gcccggtgga ccgggaaaaa
     4081 tacccgcagg cagaacagaa attccggttt gagaagacgg agccaggatg cgggaatgaa
     4141 gcagagccgg agcagggaac gcgggaaaaa acgctggttc agagcaggag aaactgcggc
     4201 ctggccggaa gaggcgtggt atctgcagaa cgagacggcg gatggggatt ttcgcccatt
     4261 gagccagttc ccgatcagcc gaatccgctt ctcatcgagt ttctcgatgc agagagtaca
     4321 gaggaacagc tggctgttct cagaagaatg gaaggctgcg tgggaaagag agagctggac
     4381 agcgtctgcg tgtatctgga tatcagcacc agatatggct ctctggaaga gcagacagag
     4441 ggaatcaggc ggtatttgaa gcttcagatg cactacgacg cgtcgaggct tcgcagaggc
     4501 aagagggacg attcgtcatg tttcatatag aagaagagct gaaaaaactt ccggctcagc
     4561 cgggagtcta cattatgcac gatgagaagg acgagattat ttatgtggga aaggcgatca
     4621 gcctgaaaaa cagagtccgc cagtattttc agagcagcag aaacaagact gccaagatcg
     4681 aaaagatggt ttctcatatt gcaagattcg agtatattat tacagattcg gagctggaag
     4741 cgctggtgct ggagtgcaac ctgattaagg agcaccgtcc ccgctataac accatgctga
     4801 aggacgataa gacgtatccc tacatcaagg tgacagtgtc ggaggaatac ccaagaatcc
     4861 tcttttccag aaccatgaaa aaagataaaa ataagtattt tggccccttt accagctccg
     4921 gagcggtgaa ggataccatt gatcttctgc atcggattta ccggatcaga acctgcacca
     4981 gaaacctgcc gcgggatatc ggaaaggaca ggccctgtct gtactaccat attaaacagt
     5041 gcgatgcccc gtgccaggga tatatttcaa aagaggatta ccagaaacag atccgtggcg
     5101 cgctggattt tctgggaggg aaatatgcgc ctgtgacgaa ggctttgact gataaaatgt
     5161 acgaggcctc agaacagatg gaatttgaga aggcggctga gtaccgggat ttaattaaaa
     5221 gcgtgaatca gatagcccag aagcagaaga ttaccagtca gagcatggac gatcgcgacg
     5281 tgattgccat ggccaaggac gagagagacg tggtggtgca ggtgttcttt gtccgggacg
     5341 gaaggctcat cgggcgggag cattttcatg tggaagccgg aacagcggaa tcgaacggcc
     5401 agattttaaa cggctttgta aagcagtttt acgccgggac gccctttatt ccccacgaga
     5461 tctggtgcca ggaggagctg gaagacgcgg atctgatcgg ccggttcctc agcgagcgga
     5521 gagggcagaa ggtaagaatt ctggttccca gaaagggaga gaaggagcgg ctggtggagc
     5581 tggcgaaaaa gaacgccaga atggttctcg ctcaggataa agaaaaaatc aagcgggagg
     5641 agcttcgaac gacaggagcc atgaatcaga ttggagggct gatagggctt gagaaggtaa
     5701 ggcggattga ggcctacgat atctccaata tcagcggttt cgagtccgta ggatccatga
     5761 tcgtctatga ggacggaaga cccaagcgga acgactacag gaagttccgc attcgaacgg
     5821 ttcagggacc ggacgattac gcttccatgc gggaagtgct gacgcggcgt ttttcccacg
     5881 gcctggcaga gcgggaggag atttctgctg agggcggaca gcttgagatg ggaagcttca
     5941 ccagattccc ggatctgatt atgatggacg gaggaagagg acaggtaaac attgccctgg
     6001 aggttcttca aaagcttcag atatcaattc cggtctgcgg aatggtgaag gatgacaatc
     6061 accggaccag gggactctat tacagaaacg aggagattcc cattgaccgg tattccgagg
     6121 gatttaagtt gatcaccaga atccaggacg aggcccaccg atttgccatt gaataccaca
     6181 gaagtctgcg cggcagagag caggtgcgct ctgtgctgga cgatatcagg ggaatcggtc
     6241 ccgccaggag aaaggctctg atgcggcatt ttaagaccat agaggctgtc agggacgccc
     6301 aggtggagga actttccgcg gtgcctcaga tgaatcaggc tgcggcggag gcagtatacc
     6361 atttctttca tgccaaagag tgacaaacgg gctgaaaaat gatagagtaa acttaggagt
     6421 acaggcagac agaatgaaag ctgtgaaagg agaaaggcca tgtatggagt gacaattaaa
     6481 gaattaatta aaaagatgga tttaaaaaat atgacgccgg agctggatac agagaaaacg
     6541 gtgctggtcc acccggatgt aaaccgtccg gctcttcagc tgaccggatt ttttgaccat
     6601 tttgacaagg agagagtgca gatcatcgga tatgtggagc aggcatactt aaatacgctg
     6661 actctggatc ggagacggta tatctacgat aagctgattt ccagcaaaat tccgtgcctt
     6721 ctctacagcc ggggcctgga gccggacgag tgcgtgctgg agctgtgcaa ctactacggc
     6781 gtgccctgca tgatttccaa gaagaccacc tccgatttga tggcagaggt gatccggtgg
     6841 ctgaatgtga agctggctcc catgatcagc atccacggag tgctggtgga cgtattcggc
     6901 gagggcgttc tgattatggg cgagagcgga atcggaaaga gcgaggcggc gctggagctg
     6961 atcaagagag gccatcgtct ggtcagcgac gacgtggtgg aaatcaagcg ggtcagcgac
     7021 gacacgctga ttggatcggc ccctgatatt acgcgccatt tcattgagct gcgcggaatc
     7081 gggattatcg acgtgaaaac cctgtttgga gtggagagcg tgaaggatac ccagtccatt
     7141 gacatggtga tcaagctgga ggagtgggat aaggacaagg agtacgaccg cctgggcatg
     7201 gaggatcagt acacggagtt tctgggaaat aaggtagtct gccactcgat ccccatccgt
     7261 ccgggacgga acctggcggt gattgtagag tccgcagccg tcaactacag acagaaaaag
     7321 atgggctaca atgcggccag agagctgtac aacagagtcc aggccaatct ggctgcgaag
     7381 aacgactgag accaaatcgg ttgaaacctg cccttctgaa gcaggcagag aaaatcagac
     7441 agagaaaatc agagaaagaa agtcagagag gaagctgcgt atggatgagt tttacagagc
     7501 gctgtgcaga gccgcagggg aggagcaggt aaagagacag gaatcaatgg ctcttcacac
     7561 tactttccgt acaggaggac cggctgcatt ttttgcatcg gttaagacgg aggaggagct
     7621 gcggcagacg gtgggcgcct gccgggaata ccaggttccc tattatatgc tgggcaatgg
     7681 aagcaatctg ctggtgggaa gcgcaggctt tccaggggtg atgatccgtc tggacggaga
     7741 actgaaagag tggaggatac tccgggagga ggaagacggc cgcgtgcttc ttaaggccgg
     7801 cgcagggctt ctcctctcta aaatcggccg ggcggcctta gaggaagggc tgacaggctt
     7861 tgagtttgcc gccggcatcc cggggacgtt aggaggcgcg gcagtgatga acgccggagc
     7921 ctatggcggc gagatgaagg atatccttgt atctgtccgg gtgatgactc cagacggcca
     7981 ggtggaagag ctgccggccg gcgggcttca gctgtcctac cgccacagct gcattcccga
     8041 gagaggatat gcggttttat cggctgtgat ggagctgaaa aggggaaata aagaggagat
     8101 ccgggagcgg atggaggatc tggcgtttcg gagaagagat aaacagccct tggagtatcc
     8161 cagcgcaggc agcaccttta agagaccgga gggatacttt gcgggaaagc tgatcgagga
     8221 cgctgggctg aagggatatt ccgttggagg agcccaggtg tcggaaaagc acgccggatt
     8281 cgtaatcaac cgggagaacg cttcccctga ggagatcaga gatctgattg aagcggtgag
     8341 aacgcgggtg tttgagacgt ccggcgtgcg gctggagccg gaggtgaagc ttctgggctt
     8401 cgggccgtcc gcctggggag acaccgcttc cgcagattca aaaaggagta attagcgtat
     8461 gcgtcttgta attgtaaccg gaatgagcgg agccgggaaa accacagctc ttaaaatgct
     8521 ggaggatatg ggattttact gcgtggataa tcttccgatt ccactgattg gaaagtttgc
     8581 ggagctggcg ggatccagaa gaggagaaaa aagccaggcg gctctgggaa ttgatatcag
     8641 aagcggcgaa tcgctggagg agctgggcgc tattttaaag gaatgggacg agagccgctt
     8701 tccctacgag attctcttcc ttgacgcggg ggacgaggtt ttgatcaagc ggtataagga
     8761 gaccaggaga agccatccgc tggcaggcct tgaccgtctg gacaggggca ttgagaagga
     8821 gcggaggaag ctggcctttt taaagaaaag ggcggattat attttagaca ccagcatgct
     8881 tctcacaaaa gaactgagaa ttgagctgga aaagattttc atttccaacg aggactacag
     8941 aagcctttat gtgaccgtgt taagctttgg ctttaagtat ggaattccgg tggacgcgga
     9001 tcttgtgttc gacgtgcggt ttctgcccaa tccctactat gtagacgagc tgaaaagcca
     9061 cacgggaaac gagcccgagg tgcaggaatt tgtcatgaaa ggcgggctgg cggaggaatt
     9121 cttaaaaaaa ctttccgata tggtgctgtt tctgcttccc cactatgtgg aggaggggaa
     9181 aaatcagctg gtcatcgcca tcggctgcac agggggaaaa caccgctccg tgacagtggc
     9241 caaccgcctc tatgagcgcc tgaaggccaa ggaggatatc ggcgtaaaga ttgaacacag
     9301 agatatcgag aaagacagca ggagaaagca ggaggtttga tttgtcgttt tcttcacatg
     9361 taaaagagga gctttccaga caggtaagcc ctgccagaca ctgccagata gcggaaaccg
     9421 cggctatttt aagtctgtgc ggaaaggtcc acatcacaga ggataaccag tacatgatcc
     9481 gcatccacac agaaaatgtg gcggttgcca gaaaatactt tacattactg aaaaaagcat
     9541 ttaatattag agcggatgtg gcaatccgca ggaatgcgtt tttaaagaaa aacaggacgt
     9601 acacagtggc ggtcagacgc agcagggacg cagtccgggt gctgcaggca gccaggcttc
     9661 tgggagacga cggggatgtc tgtgaaaata tgtccgtggt gaaaaatctg attatccaga
     9721 attcctgctg ccggagagcc ttcgtccgcg gcgcctttct ggcagcagga tccttaagcg
     9781 atccggaaaa gttctaccat ttcgagattg tctgctcctc tgaggagaaa gcagagcagc
     9841 tgagggaaat catagggact ttttccattg aggcaaaaat agttgtcaga aagaagtatt
     9901 atgtggtata tataaaagag ggcagtcaga ttgtagagat tctgaacgtg atggaggctc
     9961 ctctggccct gatggagctt gagaatatca gaatcctcaa ggagatgaga aacagtgtga
    10021 accgtcaggt caactgcgag actgccaata ttaataaaac tgtgtctgcc gctgtcaaac
    10081 agcttcagga tatcgcctat atcagagaca cagttggact ggactacctg cctgaatctt
    10141 tagctgagat cgcccaggcg agattggaac ggccagacgc tactttaaag gaacttggag
    10201 agatacttag tcctccggtg gggaagtcag gggtgaacca ccggctcaga aagatcagct
    10261 ccatcgctga gagcctgcgg ggacagaaat cacagcagca ggaattgttc cttgaaagga
    10321 atgaggagga aagttatgaa aagtaaggaa gtcacaatcg agctggcgtc aggactggaa
    10381 gcccgcccgg tagccatgct ggtacaggta gccagccagt acgaaagccg catttacatg
    10441 gaatacgcca acaaaaaggt gaatgccaag agcattatgg ggatgatgtc gctggtgctt
    10501 ccagtaggcg agaaggtggt tgtcactgcc gacggctctg atgaggacac ggcgattgca
    10561 agcattgaga aatatctgtc cgccgagtag agatgacggc agagcagagt ccataagagg
    10621 aacatagaca gatgtaaagg agggaacggc agacgctgcg ccctccttct tagcgtttcc
    10681 ggccggattt ttcaggcaca gaggcgcaga taccatacat atttaaggaa aggaaaagga
    10741 agactacatg gcttttacac atcttcatgt gcatacagag tacagccttt tagacgcctc
    10801 ctccaaaata aaggagctgg tggccagagc gaaggctctg ggcatggaca gtctggctat
    10861 tacggatcac ggcgttatgt acggagtcat tgatttttac cgggcggcca gggaggctgg
    10921 aatccgtcct gtgttaggct gtgagattta tgtgtgtcct ggatcccggt ttgaccgtga
    10981 aatcggtgtg ggagaggata aatactatca cctgattctg ctggcagaga acaacgaagg
    11041 gtatcagaac ctgatgaaga ttgtgtccgc cggctttgtg gagggctttt attacaagcc
    11101 cagagtggac tacgagactc tggagcggta cagcaggggc cttatctgcc tttctgcctg
    11161 cctggccgga gaggttcaga gaaatctgtc ccggggcatg tacgaggagg gaaagaaggc
    11221 ggctctcaga tatcagaaaa tctttgggga gggtaatttc tttctggagc ttcaggatca
    11281 cggaatcccc atgcagaaga cggtgaacca gggacttttg cgaatgagcc aggatacggg
    11341 aattccgtta gttgccacca acgactgcca ctatattaac agggaggatg aaaagtccca
    11401 cgacattctc ctgtgcatcc agactggaaa aaaggtggcg gatgagaacc ggatgcgcta
    11461 cgagggcgga cagtattacg tcaagtcgga ggaggagatg aagaacctct tcccctatgc
    11521 cctggaagct ctggagaata cccataagat tgccatgcgc tgcaacgtgg agattgagtt
    11581 tggagtgacg aagattccgc agtttgatgt gccgggagga aagacttcct gggaatattt
    11641 aaacgagctg tgcacatcag ggtttgagaa gcggtatcca gaggacgacg gaagcctgag
    11701 aaagcgtctg gactatgagc tttccgtcat acagtccatg ggctatgtgg attacttcct
    11761 gattgtgtgg gattttatcc acttcgcccg ctcccacgac atcatggtag ggccgggacg
    11821 aggctcggcg gcgggaagca tcgtctccta cagcctggga attacggata ttgaccccat
    11881 ccgctacaac ctgctctttg agcggttcct gaatccggag agagtgtcca tgcctgatat
    11941 tgatattgat ttctgcttcg aacgccgcca ggaggtcatc gactacgtgg ttcagaagta
    12001 cggaagagac cgggtggtgc agattgtaac cttcggtacc ctggcggcca agggcgtggt
    12061 ccgggacgtg ggaagggttc tggatatgcc ctacgccaag tgcgacgctg tggccaagat
    12121 gattccgggg gatctgggta tgacgcttga caaggccctg aaaacaccag agcttagaga
    12181 ggcctatgac agcgatccgg agatcaaata tctgattgac atgagcagga ggctggaggg
    12241 acttcccaga catacgtcca tgcacgcggc gggagtggtg atcagccgga ataaggtgga
    12301 cgagtacgtg cctctttcca gggcggcgga cggttccatc accacccagt ttaccatgac
    12361 tacattagag gagctggggc ttttaaaaat ggatttcctg ggtctgcgca ccctgacagt
    12421 gattcagaac gccgtgcgcc agacagagaa aacccacggc atccacattg atttgaacca
    12481 gatcgactat aatgacaggg cggtgctgga atctctgggc acaggcaaga acgacggcgt
    12541 gttccagctg gagagcggcg gaatgaagag cttcatgaag gagctgaagc cggagaacct
    12601 ggaggacatt atcgcaggta tctccctgta ccgcccgggt cctatggatt ttattcccaa
    12661 atacctgaag ggaaagaacg acagaagctc catcacctac gactgccctc agctggagcc
    12721 gattttaagc cccacctacg gctgcatcgt ctaccaggag caggtaatgc agattgtgcg
    12781 gaatctggcc ggctacacgc tgggccgaag cgatctggtg cgccgcgcca tgtccaagaa
    12841 aaaggccgcg gtaatggaga aggagaggca gaacttcgtc tacggcaatc cagaggaggg
    12901 agtgaagggc tgtattgcca acggcatcga cgagaagacc gccaacacca tctacgacga
    12961 gatgatcgac ttcgccaagt acgcctttaa caagtcccac gcggcggcct atgcggtggt
    13021 atcctaccag acggcctacc tgaaatacta ttatccggtg gagtttatgg cggctctcat
    13081 gacgtcggtg aaggacaatg tctccaaggt gtcggagtat attttaacct gccgccagat
    13141 gggcatgaag atcatgccgc cggatattaa cgagggagag ggaggcttct ccgtatcgtc
    13201 gggagccatc cggtacggcc tctcggcgat caagagtatc ggccagagcg tggtggacga
    13261 gattgtgaag gaaaggacgg ccagaggccc cttcacttcc ctggaaaatt tcattgaccg
    13321 catgagcaat aaggaggtca ataagagaac catagaaagc tttattaaat cgggagcgct
    13381 ggacagcctt cccggtacca gaaagcagaa atttctggtt tcagcggctc tgttagacca
    13441 gaaaaataag gaaaagaaaa actccatgga aggacagatg tctctgttcg attttgtgga
    13501 ggaggaagaa aaagagcagt tccagattac ctttcccgat gtgggagagt atacaaaaga
    13561 ggagcttctg gcctttgaga aggagatgct gggcgtctac gtcagcggcc atcctctgga
    13621 agagtatatg gatctctgga aaaagaatgt gacggctgtc tcctctgatt ttgttgtgaa
    13681 tgaggaggag ggaaccgcca gggtccgtga cggcgcttac gtgacgatag gcggcatgat
    13741 tacagaaaag acagtaaaaa ccacacggca gaacaagatg atggccttta ttacggtgga
    13801 ggatctggca ggaacggtag aggtgttaat cttcccaaga gattatgaga agaaccggga
    13861 acttctgata gaggatgaaa aggtgtttgt ccagggccgc gtatccatcg gcgatgatcc
    13921 ggcgggaaag ctgatctgcg agagaattac cccattttcc atggttccca gagagctttg
    13981 gctgaaatat ccggataaag aagcgtattt ttctgcagag caggaacttt tggatatgct
    14041 gaggctcagc gagggaagcg atcgggttgt catctatctg gaggcagagc gggcgaaaaa
    14101 agtgctgccg gtaaactgga gtgtcagcgc tgattctgtg ctggtggaaa ggctttctga
    14161 gaaacttggt gaaaaaaatg tcaaagtagt ggaaaaaact attgaaaaga tagggaaaat
    14221 gaattagaat gtacaggaca gaatgcatta tttttaaaga tttttgatag acgcgataat
    14281 ggaggtagaa gtagatggca aaagaggtta agacaatcgg cgtcctcacc agcggcggcg
    14341 acgctcccgg aatgaacgcg gcgatccgcg ctgtagtcag aacggcaatc aacaagggac
    14401 tgaaggtaaa aggtatcatg agagggtacg caggccttct tcaggaggag attgtggata
    14461 tgaacggcct cagcgtggcc gatatcatcg gacgcggagg aacggttctc tacaccgcca
    14521 gatgcccgga gtttaccaca gccgagggac agcagaaagg cgctgagatc tgccgcaggc
    14581 acggcatcga cggacttgtg gtaatcggag gagacggatc ctttaaggga gctggaaagc
    14641 tgtccgctct tggaatcaac accgtaggcc ttccgggaac cattgacctg gatattgcct
    14701 gtacggatta caccatcggc ttcgacacag cggtcaatac agccatggac gccattgacc
    14761 gcgtccggga tacgtccact tcccatgagc ggtgcagcat catcgaggta atgggaagaa
    14821 acgccggata tatcgcactc tggtgcggac ttgccaacgg cgcggaggat attctccttc
    14881 cggagcgcta tgacggcaac gagcaggagc tgatcagccg cattattgag aacagaaagc
    14941 gcggaaagaa gcaccatatt atcatcaacg cagagggaat cggccattct gcttccatgg
    15001 ccagaagaat cgaggcggcc acaggcattg agacaagagc cacgatttta ggctacatgc
    15061 agcgaggcgg cgctcctacc tgcaaggaca gagtgtacgc ttccatcatg ggagccaagg
    15121 cggtagagtt gctctgcgca ggaaagagca accgggtggt agcttacaag aacggagagt
    15181 acgtagatta cgatattcag gaagctctca gcatgaagaa ggacattcct gaggagcagt
    15241 acaagatcag caagatgctg attcgataag acgaaagact gcagaagtcc ccaaggggaa
    15301 gagaagacat cagggcgcag aagcgttctg gtgtcttttt cgcagatgga gaggagagac
    15361 agatggcgga aaatgttgtg ctctgcggag ccaattccta tgtggagaaa tattatttta
    15421 acgaggagtt ttctaagctt cccgagcagg tgaaggaaga actgcagatt atgtgcgtca
    15481 tgttcacgga ggacgtggga ggggtgctga ctctggagtt tacgccggag ggagagcttc
    15541 agtttaaggt ggcctgcgac gagacggact atctgtttga cgagatagga agcgccctga
    15601 aaatcaagca gtaccagatg gaaaaaagag agctgctgga ggcgctggag ctttactacc
    15661 gcgttttcat ttcaggcgga gaggacgcgg aaaagctgaa aagcctgttt ctggaggaag
    15721 aaaagcagga ggcccatgaa agaaaagcag gaagaatcga tgaatcataa aacagagaac
    15781 agattgcaga aaaagaagct gaacatcgga ggggtagagc ttccgtctcc cgtaggactg
    15841 gcgcctatgg ccggggtgac ggatctgccc ttccgcatcc tctgccggga acagggctgc
    15901 gggctgatgt gcacggagat ggtgagcgcc aaggctctgc tctacaaaaa taagaatacg
    15961 aagcctcttt tagagacagt tccggaggaa catcccctgg ctgtccagct ctttggctcc
    16021 gatccggaga ttatgagcca gatggcgctt cagctggagg aagggcctta tgatatcatt
    16081 gacatcaaca tgggctgccc ggtgccgaag attgtcaaca acggagaggg ctccgcgctg
    16141 atgaaaaatc caaagctggc cggagaaatt atctccgcca tggtaaaaaa actgaaaaaa
    16201 ccagtgacag tcaagttcag aaaaggattc aacgaccagt cagtcaacgc ggtggagttt
    16261 gccaaaatgg cagagcagag cggagcggcg gctgtgacgg tccacgggag aaccagggag
    16321 cagttttact ctggaaaagc ggactgggat atcatccggc aggtgaagga ggcggtttcc
    16381 attcccgtca tcggaaacgg agatattttc actccggagg acgcggcgcg gatgatggag
    16441 gagacgggct gcgacggcgt gatggcggcc aggggagcca agggaaatcc gtggctgttc
    16501 cacaggatta accattatct ggaaacggga gaaattctgc cgcagccgtc cctttcggag
    16561 attcgggaca tgatcctgcg ccacgccaga ctgcaggtgg aatataaggg agaattcatc
    16621 gccatgcggg agatgagaaa gcacgtggcc tggtacaccg ccgggtgtcc ccactccgcg
    16681 gccctcagaa acgatatcaa catggtggag accctggaag gattaattga gctggtagac
    16741 aaaagactcc ggtaagacgg cggagaaacc acggaatgtc ccgaaatatc agcatctgca
    16801 gggatctatt ccttgacatc gccatgcaat tcagttataa tattacgacg cggaaagaag
    16861 aaaaaaatac cggtcagagg tatctgacac aggaatagaa ggggagattc cctgtaaaat
    16921 gtaacccgaa aggaaggaaa gtatcatggc agacaagaaa catatcctca cttacacagg
    16981 cttaaagcag tatgaagatg agttacagga tttaaaggta aacaagcgtc aggagatcgc
    17041 tcagaagatc aaggaagcca gagagcaggg tgacctgtcc gagaacgctg agtacgatgc
    17101 tgcaaaggat gagcagagag acatcgaggc cagaatcgag cagctggaga agctgttaaa
    17161 gaacgcggag gtcgtagttg aggaggagat cgatcttgag aaaatcaaca tcggctgccg
    17221 tgtaaaggta ttagatatgg agttcgacga ggagatggag ttcaagatcg ttggttccac
    17281 tgaggcaaac agccttcaga ataagatttc caacgagtca ccggtaggcc atgcccttct
    17341 cggcaagaag gccggagaca ttgtagacgt agagacacag gctggagtga ttcagtacaa
    17401 ggtgctggag atccagagag tatcataaaa atcgcacaaa ggagtgaaga cagtggcaga
    17461 gcagcagaac aacagagaag agcaggagtt aaaccattta ttgaaggtgc gccgtgagaa
    17521 gctggctgag ctttgcgaaa gcggcagaga tccgtacaag gttacaaagt atgacgtgac
    17581 tgcgcacagc gcggaagtaa aagtgcgcta tgaggagctg gagggaaaag aggtatccct
    17641 ggcaggacgt atgatgtcca agcgcgtcat gggaaaggcg tccttctgca atcttcagga
    17701 tttacagggg aatatccagt cctatgtggc cagagacgag atcggcgagg aagcttataa
    17761 ggaattcaaa aagatggata tcggcgatat catcggaatc cgcggtatcg tatttaccac
    17821 gaagacaggc gagatttcca ttcatgcaaa gagtgtagag ctgctctcca agagtcttca
    17881 gatccttccg gagaagttcc acggactgac aaacacagat atgcgttacc gtcagagata
    17941 cgtggatctg attatgaatc cagaggtaaa ggacaccttt atcaagcgtt cccagattgt
    18001 gaaggagatc agaagcttct tagacggaag aggctttatg gaggtggaga cgccggttct
    18061 ggtagccaat gcaggcggag ccaacgcaag gccgttccag acacatttca acgccctgga
    18121 cgaggacgtg aacttaagaa tttccctgga gctctactta aagagactga tcgtaggcgg
    18181 acttgagaga gtgtacgaga ttggccgcgt attcagaaac gagggaaccg atacaaagca
    18241 caatccggag ttcacacttc ttgagatcta ccaggctttc accaactacg agggaatgat
    18301 ggagctgaca gagaccatgt tccgcgaggt tgccagaaag gttctgggta ctcttcaggt
    18361 agagtatgac ggcgaggtga ttgacctgga gaagccgttc gcccgcatta ccatgattga
    18421 cgctgttaag cagtacagcg gcgtggattt ccgcgaaatt aagactgatc aggaagcgaa
    18481 ggcagtggcc aaggagcatc acattgagtt tgagaaccgc cataagaagg gcgatatcct
    18541 gaatctgttc ttcgaggagt atgtagagga gaagctggtt cagccgacct tcgttacaga
    18601 tcacccggtt gacatttccc cgctctccaa gagaaagccg gaggatccgg agtacacaga
    18661 gcgctttgag ctctacatta cccgcagaga gtttgccaac gcatactccg agttaaacga
    18721 tccgattgac cagagagaga gattcctggc tcaggaggcc ttaaaggcag ccggagacga
    18781 ggaggcctgc tccatggacg acgactttat caacgccctg atgatcggta tgccgccgac
    18841 aggaggtctg ggcattggta tcgaccgttt cgttatgctg ctgaccaact cctacgccat
    18901 cagagacgtg ctgctgttcc cgacaatgaa gtctttagac gcaaagaagg gcgataacaa
    18961 ggcagagaca gcagagtcta agccgaacgc gtttgaggca gctgcagcag gcgtgtccgc
    19021 gccaagcgta cagcttgatc tttccaaggt aaagattgag ccgctgttcg aggagttcgt
    19081 agatttcgat acctttgcaa aatctgattt cagagtagtg aaggtaaaag agtgcgaggc
    19141 agtgaagaag agcaaaaagc ttctgaagtt cgttctggac gacggttccg gcaaggaccg
    19201 caccatttta agcggtatcc acgagtatta cgagccggaa gagctggttg gcaagacctg
    19261 cgtggctatc accaacctgc cgccgagacc gatgatgggt attccgtctg agggtatgct
    19321 gatttccgcc gtgtatgagt atgacggacg ggaaggctta aatctgctga tgttagatga
    19381 cgtgattccg gcgggagcga agctgtacta aagaggtcat ttactacaaa aaatcgcgtt
    19441 actacaactt ttctacaact tttgcgcgag acactacgaa accagatgaa acaatatgaa
    19501 aggcggatct gcttataaaa tgcagattcg cctttctttt tactgtggcg caattgaaaa
    19561 cagccgctcc aaaccggagc ggctgctatg caaagttttg actgtaccaa gtataacaga
    19621 tatggattta cggcgaaagg gcaggaccgt gccaatgtta tgccaatatt atgtctgatg
    19681 gaaaagggtg tagatgcttt gttcaaagtc tcttgcactt tggcaaagat tggttacctg
    19741 ttcccaattc tcacaaacaa taggggcaaa ttgttcgaaa atgcgggttc tctttttctt
    19801 gcccgaaatg cgaatatcgt gataagttgc ctttttggca ataacagatt cccaaggatc
    19861 tttgataaat tcaacttctg ccgtattatc ataggcagct acaatccatg cctctgtact
    19921 gtcacaaggg ataacaatac aggtatcatc gggttctttt agccatgtag aaagcagtcc
    19981 tttcaaatgc tccatgtaac tggtaatagg tgctccatgg ttttgacatg gaagaatgac
    20041 agggcaagca tctctatctt ccggttttat atcacattcc agaggatttc gaatgccctt
    20101 ataaggacat ttgacagacg gacacgaaca atgagcagat ttttccttcc gagatacatc
    20161 tccatccatt tgaacgacca gaaaatccag cctgggcgta atatccttca taagttgttt
    20221 gcggatatca gcattatcgc aacaccattt ccagacaccc ttccaaccgt ttccatattg
    20281 tcctgttaag tcgggttctg gttggagctg tacataataa ttagtttcat tggttatcag
    20341 gttgatgacc ttttgtaata taatatagtc tgtcggtcct tcgcagacaa ttccgatatt
    20401 tttcatagca gtgtcggcac acctcccagt ctaccattga tccagagccg ggacaaagac
    20461 tgaccttcat ttatcagttc ttgtgacaca agaattcgat tgatttgtgc gtgcccattg
    20521 tcatcacgat ctactgcaaa caagcgaata tcatcattag tcaaatcaag cccatctaaa
    20581 accaagggat tatgagtggt aaggaaaaca tgtttattgt tctgaatgat ctgttcgcag
    20641 aatacttgta tcattttttt ggcaagacgg ggattcaatg catgatcaaa actgtctacc
    20701 gcaaaaatag aaggaccctg cggatgcatg gctagagcca acataaacag cacatacaaa
    20761 gcaccttcac tggcatcata accggtaaac cgggagtttt ctttcatata gcggtctgta
    20821 aactccataa tctgacgagt ggtaggaatg ttggcgttga tattgctttt cttgggagca
    20881 tccacggaaa tatcagaagc ccaatcaatc atatcaagga tatcatccat atataaactg
    20941 ccaaaataca gttcgccatc ttcctcatgg atcaatgctt ttattgcctc agccagacga
    21001 ccgccattca gtccgattgg agtggtttga tttggatctg gaatcgtccc gcgtaaagtc
    21061 atagtattgg gttggaaaat accataagag gagaaatgtt gtgcaatttt acggccgttt
    21121 gtcagttcct gattgtcatc aatcaagaaa aaaccaatat agctgttggc ctgctgctgg
    21181 gatgcattac tgcgccccca tattctctcg tcattctgga aaaatacttc cgaatggtat
    21241 ctccagtaat ccgtatcggt aggggttgtt aggtgcacat catagcggaa ctgatcagaa
    21301 caacagtcat tctcccattc caaggaaaga tctacggtca gtttctttct tttcagatcc
    21361 ttaaaattag acttgtaaag agagggaatg cttaaacgta cacccttccg ttgaagactt
    21421 gcagaatcaa cacggtcagt catagctgcg ctcaagaggc cgatagcctc caaaatagtg
    21481 gactttccag agccattagc accaacaaac acattgattt tacctggctc aaatgatgcg
    21541 ctatacaggg acttaaagtt c
//
LOCUS       DBMDUW010000042        21301 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1555_length_21301_cov_3.137406, whole genome shotgun sequence.
ACCESSION   DBMDUW010000042 DBMDUW010000000
VERSION     DBMDUW010000042.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 21301)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 21301)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21301
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1555_length_21301_cov_3.137406"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(38..1102)
                     /gene="add"
                     /locus_tag="ACZPCR_08580"
     CDS             complement(38..1102)
                     /gene="add"
                     /locus_tag="ACZPCR_08580"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004000 - adenosine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0019239 - deaminase activity [Evidence
                     IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HIR1230967.1"
                     /translation="MNYEYTEAENREMAWFRALPKAELHCHLDGSLPRHTVRRLGKEA
                     GLALPETEEALAAALTVPADCRSLKEYLDCFSLPISCLQTYDALCTAAYDTAKAAFEE
                     GTVYLELRFAPAFSAHDGFTQKDVVGAVRDGLKKAEADLGMRTGILLCGMRHFDLEKN
                     LEIPALAEKFMGDGVCGIDLAGDEKAYPPELHSKMFSLASEMEIPFTIHAGECHSAEN
                     VRTSVLMGARRIGHGIAMAGVKEIEELCRERGVAVEMCPTSNFQTKAVEKRSDYPIRR
                     FLEQGLAVTVNTDNRTVSGTSMTEELFLLHSQFGVTKDEALRMTENAVLAAFAEEEVK
                     RELLEKLADFRKKSGQPDGR"
     gene            1314..4265
                     /locus_tag="ACZPCR_08585"
     CDS             1314..4265
                     /locus_tag="ACZPCR_08585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HIR1230968.1"
                     /translation="MRNLPGPGTVLHGFKVLSKNKIECFFASTTELFHEASRATVLCI
                     ENEDPELGFSIIYRTPQLDETDACHMAEHLVLSSCRKYRSRDIFFDMDSKSYSTFMNG
                     MTDTCCTCYPFCSVSQKQLIKLMDVALCCMEEPDALTEPFFFDREALRFELKEADGPL
                     TLSGTVLGEDWAHLTDLEENADSHTARTLYPDSLASRLPGRAHFHYSEISRERTLHIL
                     KEYYQYSNCLILLYGKMDFEAVLSFLHQEHLSHYPARQSPVSPAFFQESVLPGFRSSE
                     EKSPAYLESRTDEASVIDFALDLSAASGLELFFWDQFAQLLDNSASPLHQEARAQGLN
                     HVIQVYVDTLLIHPVLKFRLLNGDAGVKEAFLSVIRSSLQEVSVHGLSRELCLASVRE
                     SRMTDSLTREGVHLGCHVAEEIGRYWSLTGKTDYFPLYEQAFREFSADALGEQSLIRS
                     MASEALSPAASALTVTVPSPGLAEKLEQEKKDFLSRQKASMSPREIGALLLCSREFAL
                     WNERELTNQDFLIHPDELPAPADAPAFFQADLSGIEGYFSPVPGALCAGFQLYFDLSF
                     LAKEDLPFLALYQLLLTELDTPSCSSEKQKLLEQELLHDCTFDEVFPEEEAETHSHPA
                     LSVFWYGFPEDFEKSLSFLLEIMGRADYTDTRSIIRALEKYTPDYDLSQGENAASLSY
                     ALAESALRKDARFRAAANNQDIYLFFQDTLRRLKEDPAFKEELALRLSETAARILTRS
                     RMVFLAAAREEQLPSIQSAAGRILGLLPPIPGCAHSGNGCGPVQKGELLPSPIIRAAV
                     SLDASSQEIRLIGDFSKRKDFKGRYLPFLTALSDKYLKPALRYRGGAYDCGIDVSLPN
                     GYFSLWCTADPGLEETVRLFQAAGTALKEITLTQEELNGYILSAFSQAQPLSGPLNAG
                     MRAMRRQIAGIRSEYLRELLDDIPSASLEDLEQASDVIQDIIDRGSLGAAGSRSVIDR
                     AAGLFETVTHL"
     gene            complement(4356..5192)
                     /locus_tag="ACZPCR_08590"
     CDS             complement(4356..5192)
                     /locus_tag="ACZPCR_08590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0030435 - sporulation resulting in
                     formation of a cellular spore [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HIR1230969.1"
                     /translation="MPDIYSFLQTVYQFVKSLAVNMTKKMYRTAAVFTTGAAVVTVVM
                     FNSGDFSGAGKNAAVSLYGDSEESEDLTDELPSEETGNATGVRMEFQLAASNEQGQHL
                     LGSLLEKNIQDDIAQNALEVEAIEKEVLMQAQQAKKEAEEREKQRKRENAVISYTDED
                     YEVLLRIVQAEAGICDDKGKILVANVIINRVKSSRFPGNVRDVVYQRSQFSPVSNGTI
                     NTCRVTQQTRDCVDRALAGEDYSDGALFFMNRSRSASSNVSWFDGHLTYITQHGGHEF
                     YR"
     gene            complement(5545..6018)
                     /gene="ybaK"
                     /locus_tag="ACZPCR_08595"
     CDS             complement(5545..6018)
                     /gene="ybaK"
                     /locus_tag="ACZPCR_08595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013272867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA deacylase
                     activity [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HIR1230970.1"
                     /translation="MTKTNVMRLLDAAGIAYEAGEYEVDESDLSGSHAADMMGADHDS
                     MFKTLVLKGEKTGYLVCCIPVDEELDLKKTAKAAGDKKVEMIHMKELLPLTGYIRGGC
                     SPVGMKKKFPTYIEETAVLFDKIAVSAGMRGVQVMVNPEELAAYIGASFASLVKD"
     gene            complement(6015..6509)
                     /gene="leuD"
                     /locus_tag="ACZPCR_08600"
     CDS             complement(6015..6509)
                     /gene="leuD"
                     /locus_tag="ACZPCR_08600"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016287247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HIR1230971.1"
                     /translation="MKAKGHVFKYGDNVDTDVIIPARYLNATEGAELARHCMEDIDKE
                     FVNQVQPGDIIVANKNFGCGSSREHAPLAIKCAGVSCVIAETFARIFYRNAINIGLPI
                     IECPEAAASIQAGHEVEIDFDSGVITDQTTGEHFQGQAFPPFMQKIIEAGGLVNYINQ
                     GSKA"
     gene            complement(6511..7797)
                     /gene="leuC"
                     /locus_tag="ACZPCR_08605"
     CDS             complement(6511..7797)
                     /gene="leuC"
                     /locus_tag="ACZPCR_08605"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013272869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HIR1230972.1"
                     /translation="MGMTMTQKILAAHAGLESVKAGQLIEAELDLVLGNDITSPVAIG
                     EMKKMNTQTVFDKDKIALVMDHFIPNKDIKSAENCKCCREFACRHEISNYFDVGEMGI
                     EHALLPEKGLVVAGDAVIGADSHTCTYGALGAFSTGVGSTDMAAGMVTGKAWFKVPSA
                     IRFELTGKPAKWVSGKDIILHIIGMIGVDGALYKSMEFTGDGIKHLSMDDRFTICNMA
                     IEAGGKNGIFPVDEAAREYMREHSKRDFKVYEADEDAEYEETYRIDLSKLKPTVAFPH
                     LPENTRTIDEAGDIAVDQVVIGSCTNGRTEDMRTAASILKGRKVKKGVRCIVIPATQA
                     IYLQCIREGWMETFVEAGAVVSTPTCGPCLGGYMGILAAGEKCVSTTNRNFVGRMGHV
                     DSEVYLASPAVAAASAVAGKLCGPEEICSQETTGGN"
     gene            7955..8848
                     /locus_tag="ACZPCR_08610"
     CDS             7955..8848
                     /locus_tag="ACZPCR_08610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HIR1230973.1"
                     /translation="MEQHLSQYRIFYAVAKTGNISKAAKELFISQPAISKAISKLEES
                     LGLPLFTRNSRGVQLTVEGQVLFSHVSNAFDTLNRGENELRRIKDFNIGQLKIGVSNT
                     LCKYVLLPYLKGFVEQNPHIKITIESQSTAKTVSMLEQQQLDIGLVAEPKSRRNLKFL
                     PVMQINDGFVCTKSYLENLFLREGRDTDIFSEGTVMLLDRNNMSRAHVDAWFAENNVE
                     PRHILEATTMDLIIEFAKIGLGIGCVIKDFVRKELEEGSLIEIPLASPIRRRTIGFSY
                     NPSYVTKTTSQFVKFCMPEQN"
     gene            complement(8974..10026)
                     /gene="ilvC"
                     /locus_tag="ACZPCR_08615"
     CDS             complement(8974..10026)
                     /gene="ilvC"
                     /locus_tag="ACZPCR_08615"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006566903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HIR1230974.1"
                     /translation="MYLFLNFHPKEEATMAKIYYQEDCNLSLLEGKTIAVIGYGSQGH
                     AHALNAKESGCHVIIGLYEGSRSWAKAEAAGFEVYTAAEAAKKADVIMVLINDEKQAK
                     MYKESIEPNLEEGNMLMFAHGFAIHFGQIVPPKNIDVAMIAPKGPGHTVRSEYQIGRG
                     VPCLIAVAQDYTGKAHDLALAYSLAIGGARAGVLQTTFREETETDLFGEQAVLCGGVT
                     ALMKAGFETLVEAGYEPESAYFECIHEMKLIVDLIYESGFAGMRYSISNTAEFGDYIT
                     GPKIVTEDTKKAMKQILSDIQDGTFAKNWLLENQVGCPHFNAMRKREAAHQLEKTGQE
                     LRKLYSWNDSNKLIDN"
     gene            complement(10058..10558)
                     /gene="ilvN"
                     /locus_tag="ACZPCR_08620"
     CDS             complement(10058..10558)
                     /gene="ilvN"
                     /locus_tag="ACZPCR_08620"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002603814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HIR1230975.1"
                     /translation="MSRIVLSLLVDNTAGVLSRVAGLFSRRGYNIESLTVGETADPKY
                     SRMTVVSLGDQEILEQIEKQLRKLEDVHDIKELRSGHSVYRELILVKVRANASERMAI
                     NAIAEIFRASVVDVGKESVTVMLTGDQSKLDAMINLLEDYEILELARTGVTGLSRGTE
                     DVRYLP"
     gene            complement(10723..11703)
                     /gene="nudC"
                     /locus_tag="ACZPCR_08625"
     CDS             complement(10723..11703)
                     /gene="nudC"
                     /locus_tag="ACZPCR_08625"
                     /EC_number="3.6.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000210 - NAD+ diphosphatase activity
                     [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) diphosphatase"
                     /protein_id="HIR1230976.1"
                     /translation="MIQDILPHKYDNSFKQPALAKDSFLLYIHRGTILLRGRDEQGEE
                     NQEQGKKQDYREKIYASAHTLPAPDALELPAAAQLEETGLIPGLSARAEYLFSIDEIP
                     YFMVRSAEGDPALKLAEEENQETFQEDGSGKFSFQGPAYFRIMQPEYQAFAAITAVQL
                     FRWKESRKFCGCCGSRTEDSRTERALVCTKCGHTEYPKICPAVIVAVTDGDRLLMSRY
                     KGRAYRGYALIAGFVEIGETFEETVRREVMEEVGLKVKNIRYYKSQPWAFTDTEMIGF
                     FAELDGDDAIRLQEDELSEAGWYRRDEIPEDVSSISVGSEMKMAFKHQRI"
     gene            complement(11743..12531)
                     /locus_tag="ACZPCR_08630"
     CDS             complement(11743..12531)
                     /locus_tag="ACZPCR_08630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005346048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004401 - histidinol-phosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HIR1230977.1"
                     /translation="MLADYHVHSDFSWDCQTPMEAQVRAAIGAGMEELCFTDHVDYGV
                     RTEAGTFPYRDVREELARLQKRYEGQICLRYGAEFGVQTHTTASYRKDVREEPFDFII
                     LSCHQVDNLEFDNQAYQKGKSQREYNEGYYREILETVRQFDGYSVLGHLDMILRYDRQ
                     GHWPFRESRSLVEKILEQVIRNGKGIEVNTSCFRYQIGDLTPSEDILRLYREMGGKIL
                     TLGSDAHRPEQLGEKFGQVKRRLRELGFDSLCTFRRMEPEFHRI"
     gene            complement(12737..13222)
                     /locus_tag="ACZPCR_08635"
     CDS             complement(12737..13222)
                     /locus_tag="ACZPCR_08635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230978.1"
                     /translation="MGFFGRLFKGPQVDMEKSSANAKKMRVLFNQAVEQGDDYRLIFG
                     YTEDVSRFNYGFVHGSKTKIGNLIVGWNEASQTIVVIPTVPDLSGCGDPAYYRRSEIL
                     KAYRNKYPTDAFIIYPDKKGYIGINAYDWLEDEKLYVYVSQEEELAAFTDFFMNRFAT
                     K"
     gene            complement(13370..13990)
                     /locus_tag="ACZPCR_08640"
     CDS             complement(13370..13990)
                     /locus_tag="ACZPCR_08640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HIR1230979.1"
                     /translation="MPKAAYSEEDRERIRTDLVRAGLELMAKQGIQHTTVEQIYRKVG
                     ISRTFFYSFFAAKEDLIVEALYLQQPKIIEYVQKLMADPTLSWRDAVKQFLCSCCYGE
                     KHGIAVLTVEEQQLLFRHLSKESCRIFRQKQFRLFGEILENFGIKADTERIHLFTNLS
                     LTVMVVRRAIPHVLPLFVPEAADATVDFQINAIVDALEQLKTTPMP"
     gene            complement(14107..14676)
                     /locus_tag="ACZPCR_08645"
     CDS             complement(14107..14676)
                     /locus_tag="ACZPCR_08645"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004608311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HIR1230980.1"
                     /translation="MKRFSKKEIFSIPNLMGYFRILMIPVFCYLYIGKQRYLAASAAV
                     LLSSLTDLFDGKIARKFNMVTELGKLLDPVADKLTHGALALCLALRYPLMWALILLLI
                     VKEGYMAVMGAVLLKKGKKLNGAMWFGKVCTAVLFAGLLVLFLFPHLPLFWVNSLILG
                     MMAVMIFTLLNYIPVFRQMRREAGGQRGE"
     gene            complement(14710..15543)
                     /locus_tag="ACZPCR_08650"
     CDS             complement(14710..15543)
                     /locus_tag="ACZPCR_08650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008289 - lipid binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HIR1230981.1"
                     /translation="MVEIITDSSVLYTEEDAKAAGFEAISMCVHIGDMEGRDLKIDME
                     EFYRRIAEGQVPRSSQPPIGDVAEAYERYPEAEILNIAIADGLSGTYQGACAARELMD
                     HGERITVFNSRTLCGPHRYMVEKVQRMKEEGRSLSEMLRWLEWAASHTESFLIPQDFS
                     FLRRGGRLTPVAAALGSVLKLKPVMKLTEDGKRIDKCFVKRTLSAAVKGVIEHMKQAG
                     VCERHIAYVVHAAALQEAEKVREMLSQAFAGLEIHIMDLSPVFVTQGGPGCIAIQYIE
                     R"
     gene            complement(15675..16208)
                     /locus_tag="ACZPCR_08655"
     CDS             complement(15675..16208)
                     /locus_tag="ACZPCR_08655"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230982.1"
                     /translation="MCRIQKILLGTFLAGVLISGIGTGTAIAEYSSFTYLGERVLGQD
                     KMTTTSLDYTFFPEKGAIRIFPSQYSYYGGDVLELLEDPSVPEGTVRFEITCNPDLAE
                     PFLHFTEFEEEMPAVQGVLDLNWRSYTSFPLWMEAKDQMIEDLKNKSFASYRLEAIEN
                     ISIKVNPASREFILFEE"
     gene            complement(16201..17046)
                     /locus_tag="ACZPCR_08660"
     CDS             complement(16201..17046)
                     /locus_tag="ACZPCR_08660"
                     /inference="COORDINATES: protein motif:HMM:NF046861.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAS signaling domain-containing protein"
                     /protein_id="HIR1230983.1"
                     /translation="MDKKTFLEELRSSLSVLQETELNDIMDEYEQHIDMKVQSGLTEE
                     EAIAEFGNRKELTAEILEAYHVRADYEAGQNGPEKREAKEKISLWSRVVQLWDSERRA
                     VKRQILRCRDWFHKLFGKQKAAVSREKEKRAQRNGREDGTAQSGCMNSVSQKINRMSR
                     RTGNLFSRLFAQSVRMISWCCRHIWTTALWCVKAGWNVLWIFFALLCGGFGLLSLFGL
                     GVLAVLLCQGYPLAGAAIGALGVNLSLFSAAGLGLTFLWRRERNGENGEKRSAIQEEE
                     EENYV"
     gene            complement(17039..17359)
                     /locus_tag="ACZPCR_08665"
     CDS             complement(17039..17359)
                     /locus_tag="ACZPCR_08665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HIR1230984.1"
                     /translation="MNAQFKKGVLELIVLESVRVRDRYGYELVEEVSKVVDVNEGTIY
                     PLLKRLTNERYFETYLRESTEGPPRKYYHLTAAGVLYRDSLEAEWNQLTERVGQFLEE
                     CRHG"
     gene            complement(17510..17779)
                     /locus_tag="ACZPCR_08670"
     CDS             complement(17510..17779)
                     /locus_tag="ACZPCR_08670"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230985.1"
                     /translation="MERDIQKEIREKLREIEEKEQVFILRAVKQALGEGERRLQNAAV
                     RQFIEEELRRQKQLADQMKDDRNNNWEALNRVFLELLKEEQRQEG"
     gene            complement(17781..18803)
                     /locus_tag="ACZPCR_08675"
     CDS             complement(17781..18803)
                     /locus_tag="ACZPCR_08675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016360216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase beta superfamily protein"
                     /protein_id="HIR1230986.1"
                     /translation="MEEKDFRALLDTKEYEFLKTNPRLGDRIMLLGLGGSYAYGTNCG
                     TSDIDFRGITLNLPSDLLGLTEFEQYEDLHTDTVVYSFNKIVKLLLECNPNTIEILGL
                     DEEQYLILPPLGRELLENRGMFLSKRAAKSFGGYASAQLRRLQNALARDSIPQREREQ
                     HILNSVNHALEDFQRRYDRFEQGSIRLYIGPSKKPDLETEIFVDAAYRHLPLREYETM
                     CSIMYKVVKDYDKIGKRNKKKDDNHLNKHAMHLIRLFMMAIDILERGEIRTKRVKEQE
                     LLLKIRNGGFQKEDKTFAPEFYDLLADYEKRLNQADRDSVLPDSPDMKRVEEFVEYVN
                     RKALEV"
     gene            complement(18957..19355)
                     /locus_tag="ACZPCR_08680"
     CDS             complement(18957..19355)
                     /locus_tag="ACZPCR_08680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015516456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LptM family lipoprotein"
                     /protein_id="HIR1230987.1"
                     /translation="MKKRNIAAVIMTTLVLATGCGAKEPAKTPAPSKAETEAVKNEET
                     VKSEESADVPAEKEDAETSSITGTIEDIKDFMFTIVDGADAYSLSFDEKPKGLSEVKE
                     GDKVTVTYTGELSVVDAFTGTVISVEKAAK"
     gene            19534..20328
                     /locus_tag="ACZPCR_08685"
     CDS             19534..20328
                     /locus_tag="ACZPCR_08685"
                     /inference="COORDINATES: protein motif:HMM:NF018184.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HIR1230988.1"
                     /translation="MLKIGEFSKLSHLTVKALRFYEKEGLLEPAFIDPWTGYRFYETR
                     QLEDAAEIKAYRQLDLSIDEIKTICSGADRKKILSDKAKLLTAQRKEIDARLSIINYI
                     LEDIEMKYQITEKTIPAAVVYYSETTLERHQDAMQWIPSLGKEFLQLNPGIKCAEPAY
                     EFCEYLDGEYREKQIHIRHNEAVASRGMESGRIKFREIPETRVISIYHKGPYERIGEA
                     YAYIMRYAEENGYQITGPARECYIDGIWNKDSEEDWLTEIQLPARR"
     gene            complement(20361..21011)
                     /locus_tag="ACZPCR_08690"
     CDS             complement(20361..21011)
                     /locus_tag="ACZPCR_08690"
                     /inference="COORDINATES: protein motif:HMM:NF014069.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HIR1230989.1"
                     /translation="MDIRELCCLLKYAETTEEIDGKREGILGLLPAAEIMIDYDQQNW
                     THQYDLWQHSLHTVLGVPRGIDDDMLYLAALLHDAGKPQCQTQGERDGKPNMHYYGHP
                     EKSLQLVKREIVPTLEWNGDFLSETEKKRLFYYVAFHDDHVSFRKKHLRRHLKIASFE
                     EFQKLMLLQTADAKAHIQVPVIEERVQICEALAGEYGRELYQSIIEEKKAQAGRRI"
BASE COUNT         4837 a         6077 c         4668 g         5719 t
ORIGIN      
        1 acgccatcct gattctcctc tctgtgtctt tctatgccta tcttccatcc ggctgtcctg
       61 attttttccg gaagtccgcc agcttttcca gaagctcccg cttgacctcc tcctctgcaa
      121 aagccgccag caccgcgttc tctgtcatgc ggagcgcttc atcctttgtc acgccaaact
      181 ggctgtggag caggaacagc tcctctgtca tgctggttcc cgatacagtc cggttatctg
      241 tgttcaccgt aacggccagc ccctgttcca ggaaacgtct gatcgggtaa tcgcttctct
      301 tctccactgc cttcgtctgg aaattgctgg taggacacat ttctacggca acgcccctct
      361 ccctgcacag ctcctctatc tcctttactc cggccatagc gatgccgtgg ccgatgcggc
      421 gggcgcccat cagcacactg gtgcgcacgt tctccgcgct gtggcattct cccgcgtgga
      481 ttgtgaatgg gatctccatt tcagaggcca gggaaaacat cttgctgtgg agctccggcg
      541 gataggcctt ctcgtcgcct gccaggtcga ttccacagac tccgtctccc ataaatttct
      601 cagccagcgc cggaatctcc agatttttct ccagatcaaa atggcgcatt ccgcacagaa
      661 ggattccggt acgcattccc agatctgctt ccgccttttt aaggccgtct cttacggctc
      721 ccaccacgtc cttctgagta aagccgtcgt gggcagaaaa agccggtgca aagcgcagct
      781 ccagatacac ggttccttcc tcaaaggcag ccttcgccgt atcgtaggcc gctgtgcaga
      841 gagcgtcgta ggtctgaagg caggagatgg gcagggaaaa gcagtctaaa tactccttta
      901 agcttcggca gtctgccgga acagtcagcg cggcagccag ggcctcctct gtttcaggaa
      961 gcgcaaggcc cgcctctttt cccagtcttc tcactgtatg tctgggcagg gagccgtcca
     1021 gatggcagtg aagttctgcc ttggggaggg cccggaacca ggccatttct ctgttttctg
     1081 cttctgtata ttcgtaattc atcgcggtat cctcttgtct ctttttcatc attctctcgt
     1141 tttctgccta tcataccatt tattgcccgg ctgcacaagc agtcaaaact aacgattttt
     1201 tcattttgct ggtgcattct tcctcaaaat accttatact atgagacaac agagcggcgc
     1261 tttcctggat ttctgccatg aaacgccgct gaaatcagga ggacacctca tatatgagaa
     1321 atttgccggg acctggaacg gtccttcacg gatttaaagt tctttcaaaa aataagatag
     1381 aatgtttttt tgcttccacc accgagcttt tccacgaagc cagcagagcc acggttctct
     1441 gcattgaaaa tgaagatccg gagcttggat tttccatcat ttacagaacg ccccagctgg
     1501 atgagacgga cgcctgccac atggcggagc acctggttct ctcctcctgc cgcaaataca
     1561 gaagccgcga tatctttttc gatatggaca gcaaaagcta ctccaccttt atgaacggaa
     1621 tgaccgatac ctgctgtacc tgctatccct tctgctcagt cagccagaag cagctgatca
     1681 agctgatgga tgtggctctg tgctgtatgg aggagcctga cgctctgaca gagcctttct
     1741 tttttgacag ggaggctctg cgctttgagc tgaaggaggc ggacggccct ctgactctgt
     1801 caggaacggt gcttggggag gactgggccc atctgacgga tctggaagaa aatgccgaca
     1861 gccatacggc cagaaccctt tatcctgaca gtcttgcgtc ccgccttccg gggcgggccc
     1921 atttccacta ctctgagatt tccagagagc ggacgctgca tattttaaaa gaatattatc
     1981 agtattccaa ctgcctgatc ctcctatacg gaaagatgga ttttgaagcg gttctctctt
     2041 tccttcacca ggaacacctg tcacactatc cggcccggca aagtcccgtc tccccagcgt
     2101 ttttccagga atcggttctt cccggctttc gaagctctga ggagaaaagc cccgcctatc
     2161 tggagagccg gaccgacgag gcctctgtca ttgattttgc gctggatctg tccgctgcat
     2221 ccggcctgga actgtttttc tgggatcagt tcgcccagct tctggacaac agcgcctctc
     2281 ccctccacca ggaggccaga gcccagggac tgaatcatgt gatccaggtc tacgtggaca
     2341 cgctcctcat ccaccctgtc ttaaaattcc gcctcctgaa cggagacgca ggcgtgaaag
     2401 aggcctttct ctctgtgatc cggagctctc ttcaggaggt ttctgtccat gggctttcaa
     2461 gagagctctg cctggcctct gtaagggaaa gcaggatgac cgacagtctg accagggagg
     2521 gcgtgcatct gggctgccat gtcgcggagg aaatcggacg ttactggagc ctgacgggaa
     2581 aaaccgatta ttttccgctc tatgaacagg ctttcaggga attttccgct gacgctctcg
     2641 gagaacagtc tctgattcgg tccatggcct ctgaggctct ttccccggcc gccagcgcgc
     2701 tgactgtcac tgtcccgtcg cccggccttg ccgaaaagct ggagcaggag aaaaaagact
     2761 tcctaagcag acaaaaggct tccatgagtc cccgggaaat cggcgccctt ctgctgtgtt
     2821 ccagagaatt tgctctctgg aatgagcggg agcttacgaa tcaagatttt ttaattcatc
     2881 ctgacgagct tcccgctcca gctgacgctc ctgccttttt tcaggcggat ttaagtggaa
     2941 tcgagggcta tttttcacct gttccgggag ctctctgcgc aggtttccag ctctattttg
     3001 atctgagctt tctggcaaaa gaggatctcc cctttctggc gctgtaccag cttcttctga
     3061 cggagcttga cacgccctcc tgttcttcag aaaagcagaa gcttctggaa caggagcttc
     3121 tccatgactg cacctttgac gaggtatttc cggaggaaga ggctgaaacg cacagccatc
     3181 cggctctctc tgtcttctgg tacggttttc ctgaggattt cgaaaaaagc ctctcctttc
     3241 ttctggaaat catgggacgg gctgattata cagataccag gtctatcatc cgggcgctgg
     3301 agaaatatac tcctgactac gatttgtccc agggagaaaa cgcggcctct ctctcctatg
     3361 cgctggctga gagcgccctt cgaaaggacg cccgcttccg ggccgccgca aataatcagg
     3421 acatctatct cttctttcag gatacgctcc gccgtctgaa ggaagatcct gcttttaaag
     3481 aggaacttgc cctgcgtctg tcagaaactg ccgcacggat tctcaccaga agccgcatgg
     3541 tatttctggc ggctgccaga gaagaacagc ttccctccat tcagagcgcg gcgggacgga
     3601 ttctggggct cctgcctccc attcccggct gcgcccattc cggcaatggc tgcggccccg
     3661 tccagaaagg agagcttctg ccttctccta ttatacgcgc cgccgtgtct ctggacgcct
     3721 cctcccagga aatccgcctg attggagact tttctaagag gaaggatttt aaagggcggt
     3781 atcttccctt tttaaccgcc ctcagcgaca aatatctaaa accggcgctc cgctaccggg
     3841 gaggcgccta tgactgcgga atagacgtct ccctgcctaa cggatacttt tccctctggt
     3901 gtacggcaga tccgggcctt gaggaaaccg tccgcctgtt ccaggcagcc ggaactgcct
     3961 taaaagagat tactctgact caggaagagc taaacggcta cattttaagc gccttctcgc
     4021 aggcccagcc tctctcaggc cctttaaacg ccggaatgcg cgccatgcgc cgccaaatcg
     4081 ccggaatccg ttccgagtac ctcagggagc tgctggacga cattccaagc gcctctctgg
     4141 aggatctgga gcaggcctca gacgtcatac aggatatcat tgacaggggc tctctgggag
     4201 ccgcaggcag ccgaagcgtc atagaccggg cggccgggct ctttgaaact gtgacacatc
     4261 tgtaaaaaag aaaagaaaaa aagcccccgg cagaaaagga agcggttcat cgctctcctt
     4321 tcccgtcagg ggctcttgtt atgttcttaa aatttttatc tgtaaaactc gtggcctccg
     4381 tgctgtgtaa tgtaagtcag atggccgtcg aaccagctta cgttcgacga tgcggaacgg
     4441 cttctgttca taaaaaacag cgctccgtct gagtaatcct ctccggccag agcccgatcc
     4501 acgcagtctc tcgtctgctg cgttacccgg caggtattga tcgtgccgtt ggacaccggc
     4561 gaaaactggg atctctgata aaccacatcc ctgacgtttc ccgggaaccg gctgctcttc
     4621 acccggttga taattacatt ggctacaaga atctttccct tgtcgtcaca gattcctgcc
     4681 tctgcctgca caatacgaag aagcacctcg taatcctcgt ctgtatagga gataaccgcg
     4741 ttctcacgct tcctttgttt ttctctctcc tctgcttcct tctttgcctg ctgcgcctgc
     4801 atcagaacct ctttttcaat cgcttctact tccagggcat tctgggcaat atcatcctgt
     4861 atgttctttt ccagcagact tcctaaaaga tgctggccct gttcgtttga agcggcaagc
     4921 tggaattcca tgcggactcc cgttgcattt cctgtttcct ccgacggcag ctcgtctgtc
     4981 aaatcctctg attcctcact gtctccatat agggatacgg cggcattctt gccagcccct
     5041 gaaaaatctc cggagttaaa catcaccact gtcactactg cggctcctgt ggtaaacaca
     5101 gctgcagtcc gatacatttt cttagtcata ttgacagcca gtgactttac aaactgatac
     5161 accgtctgaa gaaatgagta aatgtctggc atacacactc ctctttcctc ttctctgccg
     5221 gagctctgcc ctatggcgtg ttccggccgt ttccagtaac ggggctaatt atatgggagc
     5281 ggcacagtaa atgtcaataa gtgttttaca tttttgtgac atctgacacc agcatttaaa
     5341 tatttcttaa catatttgtg agctcatcac aaaatttttt ctgttttttg ttgatttttt
     5401 atagggtttc ccgctagtca agtattacaa atattacaat tttattaatt tctacgataa
     5461 gaaaaaatcg cgcctcagca ggcctttcat tttatgtcaa ctcttttgcc tggctgaagc
     5521 acgatattct ctctttttct tctgctaatc cttcaccaga gaagcgaagg acgctccgat
     5581 gtaagccgcc agttcctctg gatttaccat aacctggaca cctctcatgc cggcgctgac
     5641 tgcaatttta tcaaataata cagctgtttc ttctatataa gtaggaaatt tcttcttcat
     5701 ccctacaggc gaacagccgc cccggatgta tccggtcagc ggcagcagct ccttcatatg
     5761 aatcatttcg acctttttat ctccggcggc cttagccgtt ttcttcaaat ccagctcctc
     5821 gtccacagga atgcagcaga ccagataccc tgttttctcg cctttcaaaa ccagggtttt
     5881 aaacatggaa tcgtggtcag ctcccatcat gtcggccgca tggcttcccg acagatccga
     5941 ctcgtccacc tcgtattctc cggcctcata tgcaatcccg gcggcgtcta aaagccgcat
     6001 tacgtttgtc tttgtcatgc cttgctcccc tgattgatat aattgaccag acctccggcc
     6061 tcgataattt tctgcataaa gggcgggaat gcctgcccct gaaaatgttc ccctgtggtc
     6121 tgatctgtga tcactccgct gtcaaagtcg atctccacct cgtgtcccgc ctggatggaa
     6181 gccgcggcct ccgggcactc gataatggga agtccgatat taatggcgtt ccgatagaaa
     6241 atgcgggcaa aggtctccgc aatcacgcag ctcaccccgg cgcatttgat ggctaacggc
     6301 gcgtgctctc tggaggatcc gcagccaaaa tttttattgg ccacaatgat atcccccggc
     6361 tgcacctgat tcacaaattc cttatctatg tcctccatac agtgtctggc cagctctgcc
     6421 ccttctgtgg cgtttaagta tctggccgga ataattacgt ctgtatctac attatctcca
     6481 tatttaaata cgtgtccttt tgccttcatc ctagtttcct cccgtcgttt cctggctgca
     6541 gatctcctcc ggcccgcaga gctttcctgc cactgcgctg gctgcggcca ccgccgggct
     6601 ggccagatac acctctgaat ctacatgtcc catacggcct acaaagttcc ggttggtggt
     6661 ggagacgcac ttctccccag ccgccagaat tcccatgtag cctcccaggc agggaccgca
     6721 ggtaggcgtg ctgactacgg ctcccgcctc cacaaaggtc tccatccagc cttctctgat
     6781 gcactgaagg taaatggcct gggtcgccgg aatgacgatg caacggacgc cctttttcac
     6841 ctttctgccc tttaaaatgc tggcagcggt tctcatatcc tctgttcttc cgttggtgca
     6901 ggaaccgatg actacctgat caaccgcgat atctcccgcc tcgtcaatgg ttctggtgtt
     6961 ttccggcaga tgagggaagg ccactgtggg cttgagctta gacaggtcga tgcggtacgt
     7021 ctcctcgtac tctgcgtcct cgtccgcctc atagaccttg aaatcccgct tggaatgctc
     7081 tctcatatat tccctcgcag cctcgtccac cgggaaaatg ccgtttttgc ctcctgcctc
     7141 gatggccata ttgcagatgg taaagcggtc gtccatagac agatgtttaa tgccgtctcc
     7201 cgtaaattcc atggatttat agagggcgcc gtccaccccg atcattccga taatatggag
     7261 aataatatcc tttccgctga cccacttggc cggctttcct gtcagttcaa accggatggc
     7321 agacggaacc ttaaaccagg cctttcccgt caccatgccg gcggccatgt ccgtgcttcc
     7381 tactcctgtg gagaaggctc ccagggctcc gtaggtgcag gtgtgggaat ccgctcctat
     7441 taccgcgtct ccggccacga ccagaccttt ttccggcaga agagcgtgct caatgcccat
     7501 ctcccccacg tcaaagtaat tggaaatctc atggcggcag gcaaactctc tgcagcactt
     7561 gcagttttcc gctgatttaa tatccttatt tggaataaag tgatccatca caagggcaat
     7621 tttatcctta tcaaacacag tctgtgtgtt catcttcttc atctctccga ttgccactgg
     7681 agaggtaata tcatttccca gaactaaatc cagctctgct tctatcagct gtccggcctt
     7741 taccgactcg aggccggcat gggcggccag aattttctgt gtcatcgtca tacccatggt
     7801 tgtgttcctc cttggagctg tgttgctttt ccatctatcg gaaaatttag tatttacatc
     7861 ataccacatg ggctgttata ataccaatat atattgcgaa tatgaactat aaggtttagt
     7921 tatagagtag agacaacaga taagaggtaa gagtatggaa cagcatttat cacagtacag
     7981 aattttctat gccgttgcca aaacggggaa tatttcaaag gccgccaagg aactgtttat
     8041 cagccagccg gccatcagca aggccatcag caagctggag gagagcctgg ggcttcccct
     8101 tttcaccaga aactccagag gcgttcagct gactgtggag ggccaggtgc ttttcagcca
     8161 tgtgagcaac gccttcgaca cattaaaccg cggcgaaaac gagctgcgcc gaatcaagga
     8221 tttcaacatc ggccagctga aaataggagt cagcaacacc ctctgcaagt acgttctgct
     8281 tccttattta aagggctttg tcgagcagaa cccccacatc aagattacga ttgagagcca
     8341 gtccacggcc aaaaccgttt ccatgctgga acagcagcag ctggatatcg gcctggtggc
     8401 ggaaccgaaa agcaggcgga atctgaagtt tctgccggtg atgcagatta acgacggatt
     8461 tgtctgcacg aaaagttatc tggaaaacct gtttctgcgt gaggggcggg atacggatat
     8521 tttttccgag ggaaccgtta tgctcttaga tcgaaataat atgtcgagag cccacgtgga
     8581 cgcctggttc gcggagaata acgtggagcc gcgccatatt ctggaggcca ccaccatgga
     8641 tctgatcatt gagtttgcca aaatcggcct tggaatcggc tgcgtgatca aggatttcgt
     8701 gagaaaagag ctggaggagg gaagtctcat cgaaatccct ctggcttccc ccatcagaag
     8761 gagaaccatc ggcttttcct acaatccgtc ctatgtgacg aaaacgacca gccaattcgt
     8821 caaattctgt atgccggagc agaattaaac ccaggcctga ttaaaatgcg cccatccaaa
     8881 agcggaggtc tccttccatc tccggaagaa tggcctccgc ttttgaacac attatcacac
     8941 actcgttttt atttgattct aaaaattcta atcttagttg tcgatcagct tattgctgtc
     9001 gttccagctg taaagctttc tcaattcctg tcctgtcttc tccagctgat gagctgcttc
     9061 tctctttctc atagcgttga aatgcgggca tcccacctgg ttctctaaca gccagttctt
     9121 agcgaaggtt ccgtcctgga tatcagacag aatctgcttc atggccttct tggtatcctc
     9181 tgtcacgatc ttcggtcctg tgatgtaatc gccgaactca gccgtgttgg agatagagta
     9241 tctcatgcct gcaaagccgc tctcatagat taagtctaca atcagcttca tctcgtggat
     9301 gcactcgaag tacgcgctct ccggctcgta gccagcctcc accagagtct cgaatccagc
     9361 cttcatcagg gctgtcacgc cgccgcacag aactgcctgc tcgccgaaaa ggtctgtctc
     9421 tgtctcctcg cggaaggtgg tctgaagcac gcctgctctc gcgccgccga tggccagaga
     9481 gtaggctaag gccaggtcgt gagccttgcc tgtgtaatcc tgggcaactg cgattaagca
     9541 gggaacgcct cttccaatct ggtactcgct tcttactgtg tggcccggtc ccttcggagc
     9601 gatcatggct acgtcgatgt tcttaggagg cacaatctgt ccgaaatgga tggcaaagcc
     9661 gtgggcgaac atcagcatat tgccttcctc cagattcggt tcgatggatt ccttgtacat
     9721 ctttgcctgt ttctcatcat tgattaaaac catgataaca tcggccttct tggcagcctc
     9781 agcggctgtg taaacctcaa agcctgcggc ctctgccttg gcccaggatc tgcttccctc
     9841 gtacagtccg ataattacat ggcagccgga ttccttcgca ttcagggcgt gggcgtgtcc
     9901 ctggcttccg tagccgatca cggcgattgt cttgccctct aataatgata aattacagtc
     9961 ttcctggtaa taaatctttg ccattgtcgc ttcctcctta gggtgaaaat taagaaataa
    10021 atacagtatt ccgtcagcct ggcgctgtga aacggcgcta cggaaggtac cgcacgtcct
    10081 ccgtgcctct tgaaagtccc gtcactcccg ttctggccag ctctaaaatc tcatagtcct
    10141 ccagcagatt gatcatcgcg tccagcttcg actgatctcc cgtcagcatc actgtcacgg
    10201 attcctttcc cacatccacc acagaggcgc ggaaaatctc ggcgatagcg ttgatcgcca
    10261 tacgctcgct ggcgttggcc ctcaccttca ccagaatcag ctcccggtaa acggagtggc
    10321 cagaccgaag ctccttaata tcgtgaacgt cctccagctt tctgagctgc ttttcaatct
    10381 gctccagaat ctcctggtct cccagagaaa cgactgtcat tctggaatac ttgggatctg
    10441 ccgtctctcc aacagtgaga ctttcaatgt tatagccgcg gcggctgaac agcccggcca
    10501 cacggctcag tacacctgct gtattgtcta ccagcagaga taatacaatt ctgctcatgc
    10561 ccttacctgc cttttctctt caaacggctc ttgcctgcct gcagcctgct gtcgcaaact
    10621 ataggcaaac ctcgccgggt ttatcaacaa taatagcaat caaacggtct tttgtcaatt
    10681 aattaaaagg aataggacct attacctgaa gatatggttc cgctaaattc tctgatgctt
    10741 aaaggccatt ttcatctcgc ttcccacgct gatggaggag acgtcctccg gaatctcgtc
    10801 tctgcgatac catccggcct cagaaagctc gtcctcctgc aggcggatgg cgtcgtctcc
    10861 gtccagctct gcaaaaaagc cgatcatctc cgtatccgtg aaggcccagg gctggctctt
    10921 gtaatagcgg atgtttttga ccttaaggcc cacttcctcc atgacctccc ggcgcaccgt
    10981 ctcctcaaag gtctctccaa tctccacaaa gccggcaatc agggcgtatc cgcggtaagc
    11041 ccttcccttg taccgggaca ttaaaagcct gtctccatcc gtcactgcca caatcacagc
    11101 cgggcagatt ttcggatact ctgtgtggcc gcattttgtg catactaacg cccgctctgt
    11161 cctgctgtcc tctgtcctgc ttccgcagca gccgcagaat ttccggcttt ccttccaccg
    11221 gaacagctgg actgctgtga tggccgcaaa ggcctggtat tccggctgca taatccgaaa
    11281 ataagccggc ccctggaagg aaaacttccc gctgccgtcc tcctgaaaag tttcctggtt
    11341 ctcctcttct gccagtttta acgctggatc cccttctgcg cttctcacca taaaatacgg
    11401 gatctcgtca atggaaaata agtattctgc ccttgcagaa agccctggga tcagtcccgt
    11461 ctcttccagc tgggccgccg caggaagctc caaagcgtcc ggcgcaggaa gggtgtgggc
    11521 ggaggcgtag attttctccc tgtaatcctg tttttttcct tgttcctgat tctcttcccc
    11581 ctgttcatct ctgcctcgaa gaagaatcgt tccccggtga atgtacaata gaaagctgtc
    11641 ctttgcaagc gccggctgtt taaacgaatt gtcatattta tgcggtaaaa tgtcctgtat
    11701 cataagtttc tcctctgttt tctatctggt taaaaagcaa cgctaaatcc gatgaaattc
    11761 cggctccatc cggcgaaagg tacacaggct gtcaaagccc agctcacgaa gccttcgctt
    11821 cacctgcccg aatttctctc ccagctgctc cggcctgtgg gcgtcggatc ccagcgtgag
    11881 gattttccct cccatttccc ggtacagcct caaaatgtcc tctgacggcg tcagatcgcc
    11941 tatctggtag cggaagcacg aggtattgac ctcaatgccc tttccgttcc gaatcacctg
    12001 ctctaaaatt ttctccacca aagacctgga ttcccgaaag ggccagtggc cctgcctgtc
    12061 gtagcgcaga atcatatcca gatgtcccag cacgctgtag ccatcaaact gccggaccgt
    12121 ttccagaatt tcccggtaat agccctcatt gtattctctc tggctctttc ccttctggta
    12181 ggcctgattg tcaaattcca gattgtccac ctggtggcag gataaaatga taaaatcgaa
    12241 gggttcctcc ctgacgtcct tccggtagga tgcagtcgta tgagtctgga cgccgaactc
    12301 tgccccgtat ctcaggcaga tctgtccctc atatcgtttc tgaaggcggg caagctcctc
    12361 cctgacgtct ctgtagggaa acgttcccgc ctccgtccga accccataat ctacatggtc
    12421 tgtaaaacac agttcctcca tcccggcccc tatggccgct ctcacctgcg cctccatagg
    12481 cgtctggcag tcccagctga aatcagaatg gacatggtaa tctgcaagca tgatcgttcc
    12541 tcctgcggct tcttcctcac cgcgtctttt ttgtatatcg tcttttccat ctcgtccttc
    12601 tcgtatccta ccacgaatcc cggctttcct caatcctgtt ttgcagaatt ctccgcaggc
    12661 aaaaaaataa tgcgggggcc gtgaagcctc cgcattgtct tgttctgttt catttctctg
    12721 gcaggcgtct tttcccttat tttgtggcaa agcgattcat aaagaagtcc gtaaaagcgg
    12781 ccagctcttc ttcctgcgac acataaacat acagtttttc atcttccagc cagtcatagg
    12841 cattgatacc gatgtatccc tttttatctg gataaataat gaaggcatcg gtggggtatt
    12901 tattccggta tgccttcaaa atttcagagc ggcggtaata cgccggatcc ccgcagccgg
    12961 aaaggtcagg tactgtggga ataaccacaa ttgtctggct tgcttcgttc catccgacaa
    13021 ttaaattgcc gatctttgtt ttgcttccat gaacaaatcc atagttaaac cggctcacgt
    13081 cctccgtata gccgaaaatc agcctgtaat catccccctg ttctacagcc tgattaaaca
    13141 gaacgcgcat tttctttgcg tttgcactgc tcttttccat gtctacctga ggtcccttaa
    13201 acaatctgcc aaaaaatccc atatttcttc ctcccaatta ttgttctttc gtacctgccc
    13261 agaaaaataa gtataaatat ttgaatttgt ttttattttt cttaaaataa aatccgcctg
    13321 aatataaggc caaagtatat cattcggacg gattccctat gcctgctgtt taaggcatag
    13381 gcgttgtttt taattgttcc agggcgtcga caatggcgtt tatttgaaaa tcaacggtcg
    13441 cgtcggcagc ttcgggaaca aacaggggca gcacatgggg aattgctctg cgcacaacca
    13501 ttacggttaa actcagattc gtaaacagat gaatcctttc cgtgtctgcc tttatcccaa
    13561 agttttctaa aatttctcca aacaggcgga actgcttttg gcggaatatt cggcagctct
    13621 cctttgacaa gtgtctgaac agaagctgct gttcttcaac tgttaaaaca gcaatgccat
    13681 gtttttctcc atagcagcag gaacagagaa attgcttcac agcatcacgc cagctcaaag
    13741 tgggatcagc catcagcttc tgtacatatt caatgatttt aggctgctga aggtacagcg
    13801 cttcaacgat caaatcttct tttgctgcga aaaaagaata aaagaacgtc cgcgaaatcc
    13861 caacttttct atatatctgc tccacagtcg tatgctgtat gccctgtttt gccatcagtt
    13921 cgagcccagc tctgacaaga tccgttctga tgcgctctct gtcctcctca gaataagctg
    13981 ccttcggcat gtcgtccccc tttttttaaa ataaaaacaa aattcaaatt ttatctttat
    14041 tttatcatac caaatcacac aattcaagaa taaactgctg caggcgctga catcccttta
    14101 aagcggctat tctcccctct gccctcctgc ctcccgtctc atctgcctga agacgggaat
    14161 ataatttaaa agggtaaaaa tcatcactgc catcatcccc aggatcaggc tgtttaccca
    14221 gaaaagaggc agatgaggga ataaaaacag aaccagcagc cctgcaaaga ggacggctgt
    14281 gcacaccttt ccaaaccaca tagcgccgtt cagctttttc ccctttttca aaaggacggc
    14341 ccccatgacg gccatgtatc cctccttcac aatcagcaga agaatcagag cccacatcaa
    14401 agggtaacgg agcgccaggc acagggctaa ggccccgtga gtcagcttgt ccgccaccgg
    14461 atccagcagt tttccaagct ctgtaaccat gttaaatttt ctggcaatct ttccatcgaa
    14521 caaatcggtg agactggaca ggagaacggc cgccgaggcc gccagatacc tttgttttcc
    14581 tatgtacagg taacagaaca caggaatcat caaaatgcgg aaatagccca tcagattggg
    14641 aatggaaaaa atctcctttt tgctgaaccg cttcatagag cacctctttt ctgttctgcc
    14701 gctttgcgct taccgttcaa tatactggat ggcgatacat cccggccctc cctgcgtcac
    14761 gaatacaggg cttaaatcca ttatgtgaat ttccagtccg gcgaaggcct ggctgagcat
    14821 ttccctgacc ttttccgcct cctggagggc cgcggcgtga accacatagg cgatgtgccg
    14881 ttcgcagact cccgcctgct tcatatgctc aatcactccc tttacagccg ccgacagggt
    14941 gcgttttaca aagcacttgt caatcctctt tccatcctcc gtcagcttca tcacaggctt
    15001 caatttcagc acagagccca gagccgccgc caccggagtc agtctgccgc cccgtctcag
    15061 gaacgagaaa tcctggggaa tcaggaagga ttccgtgtgg gacgccgccc attccagcca
    15121 ccgcagcatc tctgaaaggc ttcttccctc ctccttcatc cgctgaacct tctccaccat
    15181 ataccggtgg gggccgcaca gggttctgct gttaaagacg gtaattctct ccccatgatc
    15241 catcagctcc ctggctgcgc aggccccctg atacgtgcct gaaaggccgt ctgcaatggc
    15301 aatattcagg atctctgcct ccggatagcg ctcataggcc tccgccacat ctccaatcgg
    15361 cggctgggag gaacggggaa cctgcccctc tgcgatacgc cggtaaaatt cctccatatc
    15421 aatcttcaga tccctgcctt ccatgtctcc tatgtgaacg cacatagaaa tcgcctcaaa
    15481 gcctgccgcc ttcgcatcct cctctgtgta cagcacagaa gagtccgtta ttatctccac
    15541 cacttcaaat ccctccaacc tgctatctgg tttttaaaac cacttattgt agtttgcaat
    15601 atttgtcgag atttgtcaag agcgccggct ggaaaaacgc agccgactgg aaaagcgaag
    15661 gcgttttcca gtctctactc ctcaaacaga ataaattccc tggatgcagg atttaccttt
    15721 atggagatat tttcaatggc ctccaggcgg tagctggcga agctcttatt tttcaaatcc
    15781 tcaatcatct gatctttggc ttccatccag agtggaaagc tggtatagct tctccagttt
    15841 aaatccagga ctccctgaac ggccggcatc tcctcctcaa actccgtaaa atgaagaaac
    15901 ggctccgcca ggtctggatt gcaggtaatc tcaaaccgga ccgttccctc cggaacagac
    15961 ggatcttcta aaagctccag cacgtctccc ccataatagc tgtactggct gggaaaaatc
    16021 cgaatcgctc ccttttccgg gaaaaaggtg tagtcaaggc ttgtcgtcgt catcttatcc
    16081 tggcccagaa cgcgctctcc caggtaagtg aaggaggagt attctgcaat ggctgtgcct
    16141 gttccaattc cgcttatcag cactccggct agaaacgttc ccagcaaaat cttctgtatt
    16201 ctacacataa ttttcttcct cctcttcctg tatagcggaa cgcttctctc cattctctcc
    16261 gtttctctcc cgtctccaca gaaacgtcag gcccaggccg gccgctgaaa acaggcttaa
    16321 attgactccc agcgcgccga tggccgctcc ggccagcgga tatccctggc atagcagcac
    16381 cgccagcact cccagaccga acaggctgag aaggccgaaa ccgccgcaga gcagcgcgaa
    16441 gaaaatccag agtacgttcc acccggcctt tacgcaccac agagctgtcg tccagatatg
    16501 acggcagcac caggagatca ttctcacgct ctgcgcaaac agtctggaaa acaaattccc
    16561 ggttcttctg gacatcctgt ttatcttctg gctcacagaa ttcatgcacc cggattgtgc
    16621 cgttccatcc tccctgccgt ttctctgcgc cctcttctcc ttttctctgg aaacagccgc
    16681 cttctgcttt ccaaaaagtt tgtgaaacca gtctctgcac cgcagaatct gcctctttac
    16741 agctcttctt tcagaatccc acagctgaac cacgcggctc cacaggctga ttttttcctt
    16801 cgcctctctc ttttccggtc cgttctgtcc agcttcgtaa tcagctctca catgataggc
    16861 ctccagaatt tctgctgtca gctccttcct gtttccaaac tcggcaatcg cctcctcctc
    16921 tgtcaggccg ctctgcacct tcatatcaat atgctgctcg tactcgtcca taatgtcatt
    16981 cagctccgtc tcctgaagga cggaaagcga tgacctgagt tcttctaaaa atgtcttctt
    17041 atccatgtct gcactcctct aaaaactgtc ctactctctc tgtcagctga ttccactctg
    17101 cctccaggct gtcgcggtac agaacgcccg ccgccgtcag gtgataatat ttccgcggag
    17161 gcccctctgt ggactcccgc agatacgtct caaaataccg ctcgtttgtc agacgcttca
    17221 aaagcggata aatcgtgcct tcatttacat ctaccacctt cgacacctcc tccaccagct
    17281 cgtagccgta ccgatccctg actcggactg attccagcac tatcagctcc agaacacctt
    17341 ttttaaactg tgcgttcata tgcgtactct gcctttctct ggtactgttg attttataat
    17401 actatattat acctactact atgtaatgtc aagtagtgga caaaattttc tcactgcaga
    17461 cgcatgaaca gacgcataaa cgcctgcagt ttttgcctaa gaaatccttt tagccctcct
    17521 gcctctgctc ctctttcaga agttcgagaa acacacggtt taacgcctcc cagttattgt
    17581 ttctgtcgtc cttcatctga tccgcaagct gcttctggcg gcgcagctcc tcttcaataa
    17641 actgccggac agccgcattc tgcaggcggc gctccccttc gcccaaggcc tgtttcactg
    17701 cccgcagaat aaagacctgc tctttttcct caatttccct gagtttttct ctgatttcct
    17761 tttgaatatc ccgctccatc ctacacctcc agcgctttcc ggttcacata ttccacaaat
    17821 tcttccaccc gcttcatatc cgggctgtcc ggcagaacac tgtccctatc ggcctgattc
    17881 agacgcttct cataatctgc caggagatcg taaaactccg gggcaaaggt tttatcctcc
    17941 ttctgaaaac cgccgtttct gatttttaaa agaagctcct gctctttaac cctctttgtc
    18001 cgtatctcgc ctctctctaa aatatcaatg gccatcataa agaggcggat caggtgcatg
    18061 gcgtgcttat tcagatgatt gtcgtccttc tttttattcc gttttccaat tttgtcgtaa
    18121 tcctttacca ccttatacat gatcgagcac atggtctcat actcccgcag aggcagatgt
    18181 ctgtacgctg cgtccacgaa aatttctgtc tccaaatccg gcttttttga cggtccgatg
    18241 tagagacgaa tacttccctg ttcaaaccga tcataccttc tctgaaagtc ttccagtgca
    18301 tggttcactg aattcaatat gtgctgctcc cgctctctct gaggtatgga atccctggca
    18361 agggcattct gcagacggcg cagctgggcg ctggcatagc cgccgaagga cttggccgcc
    18421 cgcttcgata aaaacatgcc gcggttctcc agaagctctc ttcccagagg cggcagaatc
    18481 agatactgtt cctcgtcaag ccccagaatc tcaatggtat tgggattgca ttccaggaga
    18541 agctttacaa tcttattaaa agagtagacg accgtatctg tatgcagatc ctcgtactgc
    18601 tcaaactctg tcagacccag cagatccgat ggaagattca aagtgatccc ccgaaagtca
    18661 atatcgctgg ttccgcagtt tgtcccataa gcatagcttc cacccagacc aagcagcatg
    18721 attctgtccc ccagcctggg atttgttttt aaaaattcat attcttttgt atctaacagt
    18781 gccctgaaat ctttctcctc cattgtccgc ctccctgctg ccaaaactgt ctctgcaaat
    18841 tttcttattt ctgttcatct tatcatagaa cgcggcatga ttccatcaca agctgatgaa
    18901 aaaaggacct ttccctgcag gctgcagaaa aacgtcctct ttcccgtact ttctatttat
    18961 tttgcggctt tttcaacgga aatgacagtg cctgtaaacg catccactac gctcagctct
    19021 cctgtgtagg ttactgtaac cttgtctcct tccttcacct cagaaagacc cttgggtttc
    19081 tcatcaaagg ataacgaata cgcatccgcg ccgtctacaa tcgtaaacat gaaatccttg
    19141 atatcctcga tggttcctgt gatagaagaa gtctctgcgt cttccttctc tgcaggcacg
    19201 tccgcagact cctcgctttt aactgtctct tcattcttaa ctgcctctgt ttcagcctta
    19261 gagggcgccg gtgtcttggc aggttccttt gccccgcatc ctgtggcaag aaccagagtg
    19321 gtcataatca ctgctgcaat atttcttttc ttcataatct taaacctcca taaatgagaa
    19381 tatctttttg cggctctttc acagccgtca tattctttag atggaaaagt cctggaaaaa
    19441 gttggaatcc tgttaaaaat attttatact tttacttgac tctgctctta gaggaggatt
    19501 tagactgata ctgcacagag aggaggatat caaatgctga aaatcggcga attttcaaag
    19561 ctttcccatc ttacggtaaa agctctgcgc ttttatgaga aggagggcct gctggaaccg
    19621 gcgtttattg atccgtggac cgggtaccgt ttttatgaaa ccaggcagct ggaggacgcc
    19681 gctgaaatca aagcttaccg ccagctggat ttgtctatcg acgaaattaa aacgatctgt
    19741 tccggagcag acaggaaaaa aattttgtct gataaggcaa agcttctgac cgctcagaga
    19801 aaggaaatcg acgcccgcct ctctattatc aattatattt tggaggatat agaaatgaag
    19861 tatcagatca cagaaaaaac gattccagcc gctgtcgttt attattcaga aacgacgctg
    19921 gagcgtcacc aagacgcaat gcagtggatc ccctctcttg gaaaagaatt ccttcagctg
    19981 aatcccggca taaagtgcgc cgaaccggct tatgaattct gcgaatatct ggatggagaa
    20041 tacagggaaa aacagatcca tatccggcac aacgaggcgg tcgccagccg cggaatggaa
    20101 agcggcagaa taaaatttcg tgaaattcca gaaacccgcg tcatcagcat ttatcacaaa
    20161 ggtccctatg agagaatcgg agaagcctac gcctatatta tgcggtatgc cgaggaaaat
    20221 ggttatcaga taaccggccc ggccagagaa tgttatatcg acggtatctg gaataaggac
    20281 tctgaggagg actggctgac agaaattcag ctgccagcca ggagatagcc cacgagagtt
    20341 tctgcgggac gtacaggcgg tcagattctt ctgcccgcct gcgctttttt ctcttctatg
    20401 atactctggt acagctctct cccgtattct cctgccagag cctcgcaaat ctgcactctc
    20461 tcctctatga ctggaacctg aatgtgggct tttgcgtccg cggtctgaag aagcatcagc
    20521 ttttgaaatt cctcaaacga agcgattttt aaatgacgcc tcaaatgctt tttcctgaag
    20581 ctcacatgat cgtcatgaaa tgcaacgtaa taaaacagcc gctttttttc tgtttctgac
    20641 aaaaaatccc cattccattc cagcgtcgga acaatctctc ttttcacaag ctggaggctt
    20701 ttctcaggat gtccgtagta atgcatattt ggttttccat cgcgttcccc ctgagtctgg
    20761 cactgcggct ttcccgcatc gtgcagcagg gccgccagat acagcatatc gtcgtctatt
    20821 ccccgcggca ctccgagaac ggtgtgcaga ctgtgctgcc agagatcata ctgatgcgtc
    20881 cagttctgct gatcatagtc gatcatgatt tctgctgccg gaagcagccc cagaattccc
    20941 tcccgtttcc cgtcaatctc ctctgttgtt tctgcatatt tcaataaaca gcataattcc
    21001 ctgatgtcca tctgaacgtc tcctatctct ggtgtttctt gtacactgac gctaaggcat
    21061 attcataata ttaagcgtct tcctgctctt ttgtaatatc gcctaaggat attataagca
    21121 ttccctcttc ttcatatggt aatattttct atagcgttta tcgcagtttc taactgctca
    21181 gcatagttcc aataatctga tggcagatta gaaatttcac tcatatcatt atcatcaaaa
    21241 tgatatacca tgtgccgtat tagttgattc tgaataaaat ataattttct tagttccgga
    21301 a
//
LOCUS       DBMDUW010000043        21100 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1569_length_21100_cov_2.906376, whole genome shotgun sequence.
ACCESSION   DBMDUW010000043 DBMDUW010000000
VERSION     DBMDUW010000043.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 21100)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 21100)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21100
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1569_length_21100_cov_2.906376"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            511..825
                     /locus_tag="ACZPCR_08695"
     CDS             511..825
                     /locus_tag="ACZPCR_08695"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translin family protein"
                     /protein_id="HIR1230990.1"
                     /translation="MDEAVKAELERLRDEDRRQNKRIEVLDESVKAIQDLVLSVHTLA
                     HDMKGMLEEQKELGKRLDKLEQEPGNRWRRMWDKVIDTAVGIIAGGAVTGLVILASQY
                     IK"
     gene            843..1178
                     /locus_tag="ACZPCR_08700"
     CDS             843..1178
                     /locus_tag="ACZPCR_08700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230991.1"
                     /translation="MDVTVLMQYVSYVLIAIGTMAFLVSVITQVVKCWPGFDKLPTSA
                     VVIVLSLILCPAVLVAVMAWMKQPIEWYMIFACILAAFIVALVSMDGWERLKEIWERT
                     GYKDKQERR"
     gene            1290..1523
                     /locus_tag="ACZPCR_08705"
     CDS             1290..1523
                     /locus_tag="ACZPCR_08705"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230992.1"
                     /translation="MSRTHKCPVHGENGFDQEKAGTHIPEPLADCTCDVGATGPAAEG
                     KGNTPVGPGLEGLGNTPVGPGLGGGNTPVGPGK"
     gene            1576..2394
                     /locus_tag="ACZPCR_08710"
     CDS             1576..2394
                     /locus_tag="ACZPCR_08710"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007860380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0071554 - cell wall organization or
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HIR1230993.1"
                     /translation="MGRDITKCHPSLQAAFKELAAKCHAQGLIIGLGECFRTVAEQDA
                     LYAQGRTEPGSIVTNAKGSSYSSQHQWGIAFDFYRNDGKGAYNESGDFFRRIGQIAKS
                     IGLGWGGDWTSIVDKPHIYLPNWGSGTGILKQQYGTFEKFRQTWAAEKKEYIYQPIST
                     GSARVEVTASSLVVRDAPGGKDTGGRYYTGNRIKPLRKALSGSERWFETDRGWISADY
                     LQGWILEGGQWWYLKPGYTYPAGRLEVIDGKCYCFDFNGWMLTADRIREDGEVI"
     gene            complement(2418..2513)
                     /locus_tag="ACZPCR_08715"
                     /pseudo
     CDS             complement(2418..2513)
                     /locus_tag="ACZPCR_08715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008976477.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
     gene            complement(2517..2816)
                     /locus_tag="ACZPCR_08720"
     CDS             complement(2517..2816)
                     /locus_tag="ACZPCR_08720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HIR1230994.1"
                     /translation="MFGTMTNNGSRNSSAAPAEKEALMRQIDQASFAMDDVLLYLDTH
                     PTDQEALNYYHHAAGLRREAMEAWQTQYGPLLVDSVKNMDRWTWMTEKWPWEGEV"
     gene            complement(2816..3346)
                     /locus_tag="ACZPCR_08725"
     CDS             complement(2816..3346)
                     /locus_tag="ACZPCR_08725"
                     /inference="COORDINATES: protein motif:HMM:NF022460.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HIR1230995.1"
                     /translation="MNCYDQQYSGVKEKEPLSSRSVRSQIGNSSARDWRNANVMPVRD
                     SVSGQEYQNQKETVVERQALYGQYGEWGWSCPNPGCSPSWQNPAADPGQTAAPGRQTA
                     AEPGPGPVLRPEPGNNTDENPPVSGCPVDFSNYPVGMAYVPMQRWGKTYDLDAGFSRG
                     TIFPDLDLPFLAGRCI"
     gene            complement(3466..4059)
                     /locus_tag="ACZPCR_08730"
     CDS             complement(3466..4059)
                     /locus_tag="ACZPCR_08730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004848478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015109 - chromate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015703 - chromate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HIR1230996.1"
                     /translation="MTVIFELLLEFLQIGLFSIGGGYAVIPLIKEHAVDLKGWLSIQE
                     FTDIITISQMTPGPLAVNTSTFVGLQTGGLAGAAAATLGCVFSGFVISLILCRCFERY
                     RQSAYGQQILKGLKAASIGLILSAAMTIFVIAFASNGSELAESTDPIKKLAETAANLN
                     WTAVAVFAAALILIRKVRLNPVLVLALCGIAGGIAYL"
     gene            complement(4064..4633)
                     /locus_tag="ACZPCR_08735"
     CDS             complement(4064..4633)
                     /locus_tag="ACZPCR_08735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009288790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015109 - chromate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015703 - chromate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HIR1230997.1"
                     /translation="MKKTTLRQLAWLFCINLFISAFTFGGGYVVIPMIRKYFVQKKHF
                     LTEEEVMELAAISQSSPGAIAVNLSSLAGYKTAGLPGAVVSCIASVLPALIILSVISA
                     WYESFSQNVLVNAVLKGMEAGAAALIADLILDMVQVIKNEKSRLLTAMVPAAFAASFF
                     LNLNVALILLACCCICVGEVWYTNRKGGC"
     gene            4837..5748
                     /locus_tag="ACZPCR_08740"
     CDS             4837..5748
                     /locus_tag="ACZPCR_08740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009288789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HIR1230998.1"
                     /translation="MTIRHLTVFKAVCEEESITRAAKRLFMTQPAVSHVIADLEDRAG
                     APLFDRASRRLRLNQMGRQLYEKSCRVLEAYEELEKSMENLEQRTALRVGSSITIANF
                     WLPGIISRFSKHAPDVPVEVAVDSAWRTFQRLEANEIDIAFIEGASYQEKFDSISFSS
                     YQVIPLCAPDYFKERLFHRGERGESGWTLPPRALSEERLLLREKGSAIRDVFDGAMIQ
                     QDLKLSASWVSVNSQTLLHAAEAGLGITFLPDRLAEEWLEQGRLITFSLKGISLKNEN
                     HLALLKGKYISEPMKLFIRLAQDPELF"
     gene            5901..6134
                     /locus_tag="ACZPCR_08745"
     CDS             5901..6134
                     /locus_tag="ACZPCR_08745"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1230999.1"
                     /translation="MPRGKRKTSREKLEELRETIASQEAQLKELRQREKELLKQQKEE
                     ELRRLARMMEEQQVSADKLAEILKEARLSRAGA"
     gene            complement(6176..6952)
                     /locus_tag="ACZPCR_08750"
     CDS             complement(6176..6952)
                     /locus_tag="ACZPCR_08750"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HIR1231000.1"
                     /translation="MISFDLDMTLLDHKTGQITPSALKAVELLRKRHKIVLATGRDMD
                     NYYSCRYRDILKPDGIVHMNGTKVTAGGTLLYEHTFDPALLKELLAYCDAQGFAIGVT
                     VKDDDFYIHPEVVEESDRLHWGISGRRFRDPGQLLNMKIRTLAFVGNEKQATQIERDF
                     PTLRLPLFAGKHGADVIEKGHSKADGLRLLAGYFGEDPSLKDTVAFGDSMNDIEIIQA
                     AGTGVAMGNAIEELKACADFVTDSIEKDGIWKACSCLKLF"
     gene            7173..7246
                     /locus_tag="ACZPCR_08755"
     tRNA            7173..7246
                     /locus_tag="ACZPCR_08755"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7207..7209,aa:Pro,seq:ggg)
     gene            7341..7760
                     /locus_tag="ACZPCR_08760"
     CDS             7341..7760
                     /locus_tag="ACZPCR_08760"
                     /inference="COORDINATES: protein motif:HMM:NF021252.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HIR1231001.1"
                     /translation="MTEERVEELAEKAAALHRSGYNCAQAVACALSGEVGVDEDLCFR
                     LMEGFGLGMGQMHETCGAVSGAVAALGFRNSQGRENPTTKASTYSIVRQVGEQFLEKN
                     GSTSCMELKGLTGKGVLRTCPGCVEDAVRIACGLLEE"
     gene            complement(7778..8554)
                     /locus_tag="ACZPCR_08765"
     CDS             complement(7778..8554)
                     /locus_tag="ACZPCR_08765"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231002.1"
                     /translation="MIDSKDDKDKKQTKTAAGSGMERTAPHEIRPASERVYSSRRGRS
                     RRRPSSPEPLEDERSAFSEDDGDEIDNPVSAKQRKRNKKKRKKKSLSISLSSLPKIKL
                     PSGLSVLIARFSQLACCLLMVKAAWTPLLPLINGRDGLGSVRMVLTERNYSLACYLAL
                     SGSYLAFTALSSLWILTKRHFASGDRVISADMGRGITAFLLLSLAFWNAPAVMEALAG
                     QPLLPGSSRFLEIMVPLSKPLFKTCVLGLLLSLLRRVLKK"
     gene            8815..9825
                     /gene="asnA"
                     /locus_tag="ACZPCR_08770"
     CDS             8815..9825
                     /gene="asnA"
                     /locus_tag="ACZPCR_08770"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0070981 - L-asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HIR1231003.1"
                     /translation="MEHLIVPENYEPAIGLRETQVAIKIIKDFFQRELAKQLNLTRVS
                     APLFVLPESGLNDNLNGVERPVSFGIKEQKDRPAEIVHSLAKWKRMALKQYGFQPGEG
                     LYTDMSAIRRDEDTDNIHSLYVDQWDWEKIITREERTRETLELIVKAVYKALKVTEDY
                     MAYEYEYIGRYLPDHIEFVTTQQLEDMYPDCTPKEREYKIAKLHKAVFIEQIGDKLKS
                     GEKHDGRAPDYDDWKLNGDIIVYYPVLDIALELSSMGIRVDEAVLREQLQKAGCEERA
                     ELAFQKELLEGKLPCTVGGGIGQSRICMFYLRKAHIGEVQSSIWPDGIRAEAEKHNIF
                     LL"
     gene            9847..11643
                     /locus_tag="ACZPCR_08775"
     CDS             9847..11643
                     /locus_tag="ACZPCR_08775"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002576250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HIR1231004.1"
                     /translation="MDTVNERIQALRAMMKERGIDAYLVPTSDFHESEYVGSHFECRK
                     FITGFTGSAGAAVITLKEAGLWTDGRYFVQAGKQLQGSEVKLFKMGQEGVPTIEEYLA
                     ENMPENGVLGFDGRVVNEEFGEELLARLQKKNVTAASGEDLIGALWTERPNLPAEKVW
                     VLDVKYAGKSAKDKIADLREAMKKNRATVHILTTLDDIVWLLNIRGNDVPCNPVVLSY
                     AVVTEDKFFLFINDKTLDSQTKAYLEGLGVKIKPYDDIYVLAKTFRNERILLEKSRVN
                     FAVCQSLDESNEIVNQMNPTASAKAVKNPVEMENMRKAHIKDAVAMIRHLRWMKENIG
                     TLDMDEMSVQRHLDQLRFETEGNLGLSFGTISAYGENAALCHYSATPETNKKLEPRGL
                     YLVDSGGQYYEGTTDITRTIALGPVTEEEKKCFTLVAACMLRLLNVRFPYGCHGYNFD
                     FAARELLWREGLDFNHGTGHGVGYLLNVHERPNGVRWRVVPERQDNAVFEEGMVTSDE
                     PGLYFEGKFGVRTENLMLCVKDVKNEYGQFMKFENLTWVPIDRDAIDTRWLEKRDLEL
                     LNEYHRQVYEVMAPHLSEEDRSWLEKATAPIA"
     gene            11770..13050
                     /locus_tag="ACZPCR_08780"
     CDS             11770..13050
                     /locus_tag="ACZPCR_08780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013271977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HIR1231005.1"
                     /translation="MRQYRPDLQVCETAAESRGYLQVDVVNEENNFPVTDAVVTVQEP
                     GEGGRILEELPTDQSGQTEQLELAAPDMALSLESQNTIRPYSVYNLKISAPGYEDAEI
                     TGTEILPGVTAIQPVRLRPVKVSASETETVRIPGHTLYETYPPKIAETEVKPVRESGE
                     IVLSRVVVPQTVVVHDGVPTDRSAKDYYVPYRDYIKNVASSEIYATWPQSSIVANVLA
                     IMSFTLNRVYTEWYRNQGYDFTITSSTAFDHKWIYGRDIFDTISVVVDDIFDSYLSRP
                     DVKQPILTQYCDGKKVSCPGWMTQWGSCALGEQGYSPMEILRNFYGSDLYINTAEQIS
                     GIPASYPGTELSTGSRGDKVRQLQEQLDAIATVYTAVPSLTPDGIYGPATERSVKAFQ
                     SIFGLPQTGTVDFATWYKISHIYVAITRIAELNG"
     gene            13113..14531
                     /locus_tag="ACZPCR_08785"
     CDS             13113..14531
                     /locus_tag="ACZPCR_08785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006779476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1231006.1"
                     /translation="MAKERNAGKKGKQGNGITEGVIWKQLLIFFFPILFGTFFQQLYN
                     TVDAVIVGRFVGKEALAAVGGSTGTLINLLVGFFVGLSSGATVIISQFYGGGREKRVS
                     EAVHTAIAFSLACGVGLMVIGIAASPIALRAMGTPDDIMQYSLSYIRIYFLGIIPNLV
                     YNMGAGILRAIGDSKRPLYYLMASCFTNIVLDLVLVVWLRLDVRGAAIATIVSQLVSA
                     VLVVLQLLRTKDSYRLVIRKIRLNLFMVMRIVRIGLPAGLQSVMYSASNIIIQSSVNS
                     LGTDTVAAWTAYSKIDSVYWMIISALGISITTFVGQNYGAGKLDRVKRGIYVCLGLSF
                     LITAILSVTLYLGGGYIYLMFTADAAVIAKGMEILHFLVPAFATYVCIEVLSGALRGT
                     GDCWIPMIMTAVGVCALRVLWILVAVPLKPDILTVVFSYPLTWSITSILFLVYFYCFS
                     SLKKFNVPLPRLRRRRKHAGAV"
     gene            14515..15261
                     /locus_tag="ACZPCR_08790"
     CDS             14515..15261
                     /locus_tag="ACZPCR_08790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004462234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HIR1231007.1"
                     /translation="MLEQYKKKGTVCMEYNSMNQWGEIQASQRESLSAYTAKTFLWMF
                     AGLLVTFAMTYASYATGLVLLVFSNSYGILMLTGAELLVVIFMSARVHKISVGTARAM
                     FLLYSALNGVVFSAYFLIIGSGMLMFIFGATAVFFGLMAGVSYIARVDLSGIRPLLIG
                     GLIFLVVFQFLAMFLNLTSMETIMCYVGILIFLGLTAYDVGMIRRNYQMFSGNEELLA
                     KASIFSALELYLDFINIFLYLLRLFARNRD"
     gene            complement(15354..15971)
                     /locus_tag="ACZPCR_08795"
     CDS             complement(15354..15971)
                     /locus_tag="ACZPCR_08795"
                     /EC_number="1.11.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013271981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004096 - catalase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HIR1231008.1"
                     /translation="MWTYEKRLQFPVNIKTVCPKTAQLIISQFGGPDGELAASMRYLS
                     QRYSMPCRKISGLLTDIGTEELAHLEIICSIIFQLTRNMKPEDARTAGFDAYYIDHTA
                     ALWPQSAGGVPFNACEFQSKGDAITDLTEDLSAEQKARTTYDNLLRVITDPDVKAPLR
                     FLRAREIVHFQRFGEALEQLKDSLDRKNYYYFNPEFDKQFMKTEI"
     gene            complement(15972..16253)
                     /locus_tag="ACZPCR_08800"
     CDS             complement(15972..16253)
                     /locus_tag="ACZPCR_08800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015541099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HIR1231009.1"
                     /translation="MLGNAETPSRSALLHEIDKVSFAVNDLTLYLDTHPDCQEGLARF
                     QKEAARRKELMNQYAKAYGPLTAGCVCDLGGADRWSLQDGPAPWEGGMI"
     gene            complement(16243..16428)
                     /locus_tag="ACZPCR_08805"
     CDS             complement(16243..16428)
                     /locus_tag="ACZPCR_08805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013271983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HIR1231010.1"
                     /translation="MTTVNDDQLDCGCSCRLDLAIASVPRQSWEEPQDLETALLHGCL
                     FPSLDMPFFAGGDAYVR"
     gene            16737..18188
                     /locus_tag="ACZPCR_08810"
     CDS             16737..18188
                     /locus_tag="ACZPCR_08810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002568200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="HIR1231011.1"
                     /translation="MSNSANTSAGKRIEALLDDNSFVEVGAYVKARSTDFNMAAQNTA
                     ADGVITGYGTIEGNLVYVYSQDASVMGGSVGEMHAKKISNVYRMAMKMGAPVIGLVDC
                     SGLRLQEATDALDGFGQMYLNQTMASGVVPQICAVFGSCGGGMAVSSAIADFVFMEEK
                     AKMFVNSPNALAGNDEKKCDTASADFQSGESGLADVVGSAEEILAKVRTLVSVLPANN
                     EDDMSYDECGDDLNRLCENIESFRGDTGKALSMISDDGFFFEVKENYGPEMVTAFIRL
                     NGMTVGCVANRTEVLDEENEKTAEYEPVLGARGCDKAAEFVSFCDAFNIPVLALVNVK
                     GYKQSKCTERRIAKAAGRLTYAFANADVPKVTVVIGEAYGSAYVTMNSKSIGADIVYA
                     WPDAKIGMMDAAAAVKIMYAEEISASDKAAALISEKAAEYEALQSSAAAAAGRGYVDD
                     IIKADETRQRVIAAFEMLFTKREGRPSRKHGTV"
     gene            18205..19107
                     /locus_tag="ACZPCR_08815"
     CDS             18205..19107
                     /locus_tag="ACZPCR_08815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OadG family protein"
                     /protein_id="HIR1231012.1"
                     /translation="MKQNMKRLLLLLSMITCFFVLSGCAKTEDSGSEEVTAEMEETLV
                     NGSRQYLAAFAAYSDEELEEQIKQAEKAENTVISTALSSWKSVKEDLGSLQVDEMGAP
                     LIQTDEKTGKPAVTVQAEGEDIYQVELTAVYEQRTMEFVLTAKAEDDGYGGSVLTVTE
                     MTFTPDYSIGEKLQKAFLNMLMGMGTVFVVLLFISFIISRLKMVNSWGAKKEDKTAKE
                     SAPAPVPAKPAAPVPAPAAPAPAAAPAPALVQLEESCEENLADDMELVAVITAAISAA
                     QKVPAEGLVVRSIRRKSGSNWKRA"
     gene            19138..19560
                     /locus_tag="ACZPCR_08820"
     CDS             19138..19560
                     /locus_tag="ACZPCR_08820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin/lipoyl-containing protein"
                     /protein_id="HIR1231013.1"
                     /translation="MKNYTITVNGNVYEVTVEEGFTGKASAPAARPAAPAPAAPAPAP
                     APAAPAAPAPAPAPAAPAPAAAPAAGSITVSAPMPGKILGVKTSVGAAVKKGQVILIL
                     EAMKMENEIVAPEDGTVASVNVSVGEMVEPGATLATLN"
     gene            19592..20743
                     /locus_tag="ACZPCR_08825"
     CDS             19592..20743
                     /locus_tag="ACZPCR_08825"
                     /EC_number="7.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005612560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HIR1231014.1"
                     /translation="MEYITSTLSNLLHQTAFFNLTFGNLIMILVAFVFLFLAIKKGFE
                     PLLLVPISFGMLLVNIYPDIMMSIEESSNGVGGLLHYFYLLDEWSILPSLIFMGVGAM
                     TDFGPLIANPSSFLLGAAAQFGIYAAYFLAIFMGFNDKAAAAISIIGGADGPTSIFLA
                     GKLGQTGLMGPIAVAAYSYMALVPIIQPPIMKLFTTEEERKIKMEQLRPVSKLEKILF
                     PIVVTVVVCLILPTTAPLVGMLMLGNLFRECGVVKQLTETASNALMYIVVIFLGTSVG
                     ATTSAEAFLNLDTIKIVVLGLVAFAFGTAAGVLFGKLMCKATHGRVNPLIGSAGVSAV
                     PMAARVSQKVGAEADPTNFLLMHAMGPNVAGVIGTAVAAGTFMAIFGIQ"
     gene            20765..>21100
                     /locus_tag="ACZPCR_08830"
     CDS             20765..>21100
                     /locus_tag="ACZPCR_08830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015554842.1"
                     /note="Converts oxaloacetate to phosphoenolpyruvate using
                     ATP as an energy source; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HIR1231015.1"
                     /translation="MAKIEKKPVKIVETVLRDAHQSLIATRMTTEQMLPIIDKMDKVG
                     YHAVECWGGATFDASLRFLKEDPWERLRKLRDGFKNTKLQMLFRGQNILGYNHYADDV
                     VEYFVQKSIA"
BASE COUNT         5515 a         4761 c         5821 g         5003 t
ORIGIN      
        1 gtctcaggaa tttctcctac ataggttcct gtaataccca ttatcgcaag ttgggatgaa
       61 tgaagaaaaa acgaatggaa tagatagtag atttatggta tactcttcct gttaccgccc
      121 caatactggc aacaggaagg gggtgttcat gtggaagcaa tcacatctct tgttatcgca
      181 gttgtggcag gcgtgattag ccatctcgtc tgcaaatggt tggacggcga taagtagtcg
      241 gtaatcagcc tgcggggtta agccttcccg cttaaaagta ggaatagaaa accccagagg
      301 tcgcaactcc ggggttttcg tctgtcagtc attcatgtgg aaagactcac atctctttag
      361 cctactggca ttatagcata tgcgtatttg aattacaaga tacgtatatg ctgttttttt
      421 atcctgaaat ttgaaaaagg aggacagatt ttgaaaggag gataacattt ttcctaaaaa
      481 tgacacccaa aaagaaagaa ggcgagaaag atggatgaag cagtaaaagc ggaacttgag
      541 cgtctgcgtg atgaagaccg caggcagaac aagcggattg aggtcctgga tgagtctgta
      601 aaagcgatcc aggatttagt cctgtctgta cataccctgg ctcatgacat gaaaggaatg
      661 ctggaagagc agaaagagct gggaaagcgt ctggataagc tggagcagga accggggaac
      721 aggtggcgga gaatgtggga caaggtgatt gataccgcag tgggcatcat cgctggcggc
      781 gcagttacag gacttgtcat tctggcatct cagtatatta agtagaaagt gaggaaagaa
      841 aaatggatgt tacagtatta atgcagtacg tctcttatgt cctgatcgcc atcggtacga
      901 tggccttttt agtgtcggtg atcacccagg tggtgaagtg ctggccaggc tttgacaagc
      961 tgcctacttc ggcggttgtg attgttctga gcctgatcct ttgcccggct gttctggtgg
     1021 cagttatggc gtggatgaaa cagccgattg agtggtatat gatatttgca tgtattctgg
     1081 cagcgtttat tgtagcgctg gtatctatgg atggatggga gcgtctgaaa gagatatggg
     1141 aacggacagg atataaggat aaacaggaga ggaggtgatc ccatatctcc cgcagctccg
     1201 gcgggtgatc cggggcaaac ataaatcaag acaagaggcg gcccaacagg ctgctttttt
     1261 aataaatttt tttaaggagg attcaaacta tgagtagaac acacaaatgc ccagtacacg
     1321 gagagaacgg atttgaccag gagaaggcgg gaacccatat ccctgagccg cttgcagact
     1381 gcacctgtga cgtaggagcc acaggccctg cagcagaggg taagggaaac acaccggtag
     1441 gccctggcct ggagggatta ggcaatacgc cagtcggtcc aggcttaggc ggtggaaata
     1501 cgccggttgg cccaggaaaa tagttccgac gtcgcaacag gagggaggtc ttcgggcctc
     1561 ccggaaagga gaaacatggg aagagatatc acaaaatgtc accccagcct tcaggcagcg
     1621 tttaaggaat tggccgcaaa atgccatgcc cagggcctta tcatcggcct gggagagtgc
     1681 ttccgcactg tagcggaaca ggatgcacta tatgctcagg gcaggacgga gccgggaagt
     1741 atcgtgacca atgcaaaggg atccagttat tcctcgcagc atcagtgggg aatcgccttt
     1801 gacttttaca gaaatgacgg aaaaggagct tacaacgagt ctggagattt cttccggcgc
     1861 attggacaga ttgcgaaatc aattggcctc ggttggggcg gagattggac aagcatcgtt
     1921 gacaaacccc acatctatct gccaaactgg ggcagcggga caggtatatt aaaacagcag
     1981 tatgggacgt tcgaaaagtt taggcagacc tgggcagctg aaaagaagga gtatatatat
     2041 cagcctatca gcaccggttc agcgcgggta gaggtaacag cttcctcact ggtcgtccgc
     2101 gatgctccag gtggtaaaga taccggaggt agatattata caggaaatag aataaaacca
     2161 ctcaggaagg ccctgtcagg ttctgagagg tggtttgaaa cagatagggg ctggatcagt
     2221 gccgactacc tccagggctg gatcctcgag ggaggccagt ggtggtattt gaaaccgggc
     2281 tatacctatc cggcggggcg cctggaagtc atcgatggaa aatgttattg ctttgatttt
     2341 aacggctgga tgctaacggc agatcggatc cgagaggatg gggaagtgat ttaagaggct
     2401 aatctgttac tgacttttgg cccgccatac tgactcataa taaactgtgc aatctttggg
     2461 tttggctgag agatttttac tgggtactga agccgttttt catatctcca cataagctac
     2521 acctctcctt cccatggcca cttttctgtc atccaggtcc agcggtccat atttttgaca
     2581 gagtcaacca gaagaggacc atactgtgtc tgccaggcct ccatcgcttc cctgcgaagt
     2641 ccggcagcat gatgatagta atttaatgcc tcctgatccg tcggatgagt atccaggtag
     2701 aggagaacgt catccattgc gaagctggcc tgatcaatct ggcgcataag cgcttctttt
     2761 tccgcaggag ctgcagaaga atttctgctt ccattatttg tcattgttcc aaacatcaga
     2821 tacacctccc tgctaagaat ggaagatcca gatccgggaa aatggttcct ctggaaaatc
     2881 cggcgtctaa atcataagtt tttccccacc gctgcatagg aacataggcc atgcccacag
     2941 ggtagttaga aaagtcaacc ggacatccgg aaacaggagg attttcgtct gtattgtttc
     3001 ctggctctgg tctgaggaca ggtccaggac caggttccgc tgctgtctgg cgtccgggag
     3061 cggccgtctg gcccggatcc gcggctggat tctgccacga aggggagcag cctggattcg
     3121 ggcagctcca tccccattct ccatattgcc catacaaggc ctggcgttct acaacagtct
     3181 ccttctgatt ttgatactcc tgaccggaaa cgctgtctct gactggcatg acattagcgt
     3241 tccgccagtc cctggcagag gaatttccga tctgactgcg tacagagcgg gaagaaagag
     3301 gttctttttc cttcacgccg gaatactgct gatcatagca attcatagtt tcttttccct
     3361 ttcctgattg gtttacaatc ctatcatatg ttcgacggca cgttcactgt tcatggagcg
     3421 gatatatttt taaaaagtat tgccgtgaga cagatgaaat cattgctata ggtaggcgat
     3481 tcctccggca attccgcaca gtgccaggac gagaacagga ttcagacgga cttttcgtat
     3541 cagaatcaga gccgcagcaa aaacagccac ggcagtccag ttcagattgg ctgccgtttc
     3601 ggcaagtttt ttaatgggat ctgtgctttc tgccagctct gagccattgg atgcaaaggc
     3661 aatgacgaaa atagtcatag cggcggagag gatcaggcca atggaagcgg ccttcaggcc
     3721 cttcagaatc tgctggccat aggcagactg ccggtacctt tcaaagcatc tgcatagaat
     3781 cagagaaatc acaaagccgg agaatacgca tcccagcgta gcggcggcag ctcctgccag
     3841 gccgcctgtc tgcaggccta cgaaggtaga agtgttcacg gccagcggtc caggcgtcat
     3901 ctgggaaatc gtgataatat ctgtaaattc ctgaatggac agccatccct tcaaatcgac
     3961 cgcgtgctct ttaatcagcg gaataacggc gtaaccgccg ccgatgctga acaggccaat
     4021 ctgcagaaat tccagcagca gttcaaatat aacagtcatg cttttaacat cctccctttc
     4081 tatttgtata ccacacttca ccgacgcaga tacagcagca ggcaaggagg atcagggcca
     4141 cattgagatt cagaaaaaag ctggcagcaa aggcagccgg gaccatcgct gttaaaaggc
     4201 ggcttttttc gtttttgatt acctgcacca tatcgagaat taaatctgcg atcagggccg
     4261 ccgctccggc ttccatgccc tttaaaacag catttaccag aacattttgc gagaaagact
     4321 cataccaggc ggaaatcaca gacaggataa tcagggcggg caggacggag gcgatacagc
     4381 tgacaacagc gccgggcagt ccagccgttt tgtatcccgc cagagacgag agattgacgg
     4441 caatcgcacc gggcgaggac tgggaaatag cggccagctc catgacctcc tcctccgtga
     4501 gaaaatgctt tttctggaca aagtatttac ggatcatcgg tatcaccaca tagcctcccc
     4561 caaaggtaaa ggcgctgata aataagttaa tgcagaacag ccaggcgagc tgcctgaggg
     4621 tcgttttttt cataagcagt gcttcctttc acagtattgc agcatgcctt tttcaggcat
     4681 gacgcgccgc aggcacagga aaaaggatgg ctttgcgcgc tgacgctatt ataaaacttg
     4741 ccaatatata agtaaaatta tataatttta ttattataat aactaaaaaa gcatgaacaa
     4801 aagacagaaa agcagagaga aaggaggacg gacgctatga cgattcgtca tctgaccgtt
     4861 tttaaggccg tgtgcgagga ggagagtatc accagggcgg cgaagcggct gtttatgact
     4921 cagccagcag tgtcccacgt aattgcagat ttagaggatc gggcaggtgc gccgctgttt
     4981 gacagggcgt ccaggagact gcgtttgaat cagatggggc ggcagctcta cgaaaaaagc
     5041 tgccgggtgt tagaggccta tgaggagctg gaaaaaagca tggagaatct ggagcagagg
     5101 acggctttga gggtgggatc cagcattaca atcgcgaatt tctggcttcc cgggataatc
     5161 tccagatttt caaagcatgc cccggacgtt ccggtggagg tggctgtgga cagcgcctgg
     5221 agaacgtttc agaggctgga agcgaatgaa atcgatatcg ctttcattga gggagcttcc
     5281 tatcaggaga agtttgacag tatctcattt tcatcctatc aggtgattcc cctctgcgcg
     5341 ccggactatt ttaaagagag actttttcat cggggggaga ggggagaatc aggatggacg
     5401 cttccgccca gagctctttc agaggagcgc ctgctgcttc gcgaaaaagg gagcgcgatc
     5461 cgcgacgttt tcgacggagc catgatccag caggatttga agctctccgc ttcatgggtg
     5521 agcgtaaatt cgcagacgct gcttcatgcg gcggaagcag ggctgggaat tacgtttctg
     5581 ccggacaggc tggcagagga atggctggaa caaggccgcc tgatcacatt ttctctgaag
     5641 ggaatttctc tgaaaaatga aaatcacctg gcccttttaa aagggaaata tatttcggaa
     5701 cccatgaagc tgttcataag gctggcacag gatccggagc tgttctgaca gaaaaaacta
     5761 tatttttgtt cttttgccgc ttttctggca tatattataa tgtacaagcc tgaaacctga
     5821 cgtaccagaa cacggcggcg tgccaggcag aaaaaaattc agattttatt tgagcccgat
     5881 gaaaaaagga ggcagagcat atgccaagag gaaaaagaaa aacgagcaga gaaaaactgg
     5941 aggagctgag agaaacgatt gcttcccagg aagcccagct gaaggagctg agacagagag
     6001 aaaaagaact gctgaaacag caaaaagagg aggagctgcg ccgcctggct cgaatgatgg
     6061 aagaacagca ggtaagcgcg gataagctgg cagaaatttt gaaggaagcc cgcctctccc
     6121 gcgcaggagc ctgagagcgc gggagatttt gaaatcaacg ctcagggagc agaatttaaa
     6181 acagcttcag acaggagcag gccttccaga ttccgtcttt ttcaatggaa tctgtgacaa
     6241 aatcagcgca ggctttcagc tcctcgattg catttcccat ggcgacgcca gttccggctg
     6301 cctggatgat ttctatgtca ttcatgctgt ccccaaaggc cacggtatcc tttaaagagg
     6361 gatcctcccc gaaatacccg gctaaaagcc gcagtccatc cgccttggaa tggccctttt
     6421 cgatgacgtc tgcgccgtgc ttccctgcaa acagagggag acgcagagtt ggaaaatccc
     6481 gttcgatctg agtggcctgt ttctcgtttc cgacaaatgc cagagttcgt atcttcatat
     6541 ttaaaagctg tccgggatcg cgaaagcgtc tgccggaaat accccagtga agccgatcgc
     6601 tttcctccac cacttcagga tggatataga aatcatcatc tttgactgtt acgcctatgg
     6661 caaagccctg agcgtcacag taggccagca gttcctttaa aagcgccgga tcaaaggtgt
     6721 gctcatagag cagagtaccg cctgccgtta ccttggttcc gttcatgtgt acgattccat
     6781 ccggcttcag aatgtcccgg tacctgcagc tgtaataatt atccatgtcc cttccggtgg
     6841 ccaggacaat cttgtggcgt ttacgcagca gctccacggc cttcagggcg ctgggcgtaa
     6901 tctgtccagt tttgtgatcc aagagagtca tatctaaatc aaagctgatc atgggcgtcc
     6961 tccttatact gttcgtttta accgtatcag ccgcgcagcc ttctcaatgc gcggtgaaaa
     7021 aatctgtttc tgcaattata acggatcttt caggattttc ctatagaaat aaaagaaaaa
     7081 ataaaagcat ctatattcat gaaaaaatat ttttttcaaa aaataaaaat agggcttcca
     7141 ttttttgcaa tttgtgctat aataatgagc accggggtat ggcgtagctt ggtagcgcgc
     7201 tcggctgggg gccgagaggt cgcaggttca aatcctgttg ccccgatttc agaggacaga
     7261 gaattgtgtt attgcatgat tccctgtctt tttgttttaa gacattcaat aaaatgatgg
     7321 attgcagaag gagaatttat atgacagagg aaagagtaga agaactggca gagaaggctg
     7381 cagcgcttca ccgcagcggc tataactgcg ctcaggctgt agcctgcgct ttaagcggag
     7441 aggttggagt ggacgaggat ctgtgctttc gcctgatgga gggctttggc cttggaatgg
     7501 ggcagatgca cgaaacctgc ggggccgttt ccggcgctgt ggctgctctt ggttttcgaa
     7561 acagccaggg cagggaaaat cctacgacga aagcgtctac ctatagcata gtcagacagg
     7621 tgggagagca gttcctcgag aaaaacggtt caaccagctg tatggaactg aaggggctga
     7681 caggaaaggg cgtcctgaga acctgcccgg gctgcgtaga ggatgcggtc agaatcgcct
     7741 gcggactgct ggaggaatag agggagcaag cagctcccta ttttttcaaa actcttcgca
     7801 gaaggctcag aagaaggccc agaacgcagg ttttaaacag aggctttgac agcggaacca
     7861 taatctccag gaaccggctg gatccgggca gaaggggctg tcctgccaga gcttccatga
     7921 ctgcaggcgc gttccagaag gccagagaca gaagaagaaa ggccgttatg ccccgcccca
     7981 tatctgcgct gattacccgg tcgccgcttg caaaatggcg ttttgtcagg atccagagcg
     8041 acgacagagc tgtaaaggcc agataggatc cggagagggc cagatagcag gccaggctgt
     8101 agtttctctc tgttaagacc atccgcaccg aacccagacc gtctcttccg tttataaggg
     8161 gaagcagagg agtccatgcc gctttcacca taagaagaca gcaggccagc tgggaaaatc
     8221 tggcgatcag aacagaaagg ccagagggaa gctttatttt aggaagagag gagagagaaa
     8281 tggaaagcga tttctttttt ctctttttct tattcctttt tctctgtttt gcagaaacag
     8341 gattatctat ctcgtctccg tcatcttctg agaaagcaga gcgctcgtcc tccaacggct
     8401 ctggggagga aggccgcctc cggcttcgtc cgcgtctgga ggagtacacc cgctctgatg
     8461 cagggcggat ctcatgaggc gcagtgcgct ccatgccgct gccggccgct gtttttgttt
     8521 gtttcttatc tttatcgtct tttgagtcaa tcattcttat tctcctgtac ttcgcagctt
     8581 tatgccgcca atcttttatt tcctttccac tctaccacaa aaatgtgaaa attcagagtc
     8641 ctttccctta tttttttctt acgccgtctc agataatttt ctgtaaattc agggaaaata
     8701 cctgaaaaag aagaaagtag gatattccca aaataatcaa gaggtgctat aattaattgt
     8761 caatgaatga aatgaaaaaa tgaaaaaatg aaaaagacgt aaggggactg catcatggaa
     8821 catttgattg taccagaaaa ctatgaaccg gccatcggac tcagggaaac ccaggtggcg
     8881 attaaaatta ttaaggattt tttccagagg gagctggcca aacagctgaa tctgacgcga
     8941 gtttctgcgc ccctgtttgt gcttccggaa tcaggtctga acgataacct gaacggagtg
     9001 gaacgcccgg tttcttttgg gattaaagaa cagaaggacc ggccggcgga gattgttcat
     9061 tcactggcaa agtggaagag aatggctctg aagcagtatg gctttcagcc aggcgaaggc
     9121 ctttacacag acatgagcgc gatccgcaga gacgaggaca cggataacat ccattccctc
     9181 tatgtggatc agtgggactg ggagaagatt atcacaaggg aagaacgcac cagagagaca
     9241 ctggagctga ttgtaaaggc cgtatataag gctctcaagg taacggagga ctatatggcc
     9301 tatgagtatg aatacatagg cagatatctg ccggatcaca tcgagttcgt gactactcag
     9361 cagttagaag acatgtatcc ggactgtacg cccaaggaac gggagtacaa gattgcgaag
     9421 cttcacaagg ctgtgttcat tgagcagatt ggagataagc tgaaatcagg agaaaagcac
     9481 gacggccgcg ctccggacta cgatgactgg aaattaaacg gcgacattat cgtgtactat
     9541 ccggtacttg acattgcgct ggagctgtct tccatgggta tccgtgtgga tgaggcagtt
     9601 ttaagagaac agttacagaa agcaggctgt gaggagcggg cagagctggc gttccagaag
     9661 gaacttctgg agggaaaact gccgtgcaca gtaggcggcg gtatcggcca gtcacgaatc
     9721 tgtatgtttt atttgagaaa agctcatatt ggagaggttc agtcctctat ctggccggac
     9781 ggcatccggg cagaggcaga aaagcataat attttcctgc tgtaagggat aaaggaggtt
     9841 tttaagatgg atacagtgaa cgagagaatt caggcgctcc gcgcgatgat gaaggaaagg
     9901 ggaatcgacg cttatctggt tcccacctca gactttcatg agtcagagta tgtgggaagc
     9961 cattttgagt gtagaaagtt tattacaggt tttacaggat ccgccggagc tgcggtgatt
    10021 accctgaagg aagcgggact ctggacagac ggccgctatt ttgtgcaggc cggaaagcag
    10081 ctgcagggca gcgaggtaaa gctgttcaag atgggacagg agggagttcc cacaatagaa
    10141 gagtacctgg cagagaatat gccggagaac ggcgtgctgg gctttgacgg ccgcgtggtg
    10201 aacgaggaat ttggcgagga gcttttggcc cgtctccaga agaagaatgt gactgctgcc
    10261 agcggagagg atctgattgg cgctctctgg acggagcgtc ccaaccttcc ggcagaaaag
    10321 gtgtgggttc tggacgttaa atatgcggga aaatcagcaa aagacaagat tgccgatctg
    10381 cgagaggcca tgaagaaaaa cagggcgacg gtccacattt taacgacgct ggacgacatt
    10441 gtatggctgc tgaatatccg cggaaacgac gtgccctgca atccggtggt gctttcctac
    10501 gcagtggtga cagaggacaa attcttcctc tttattaatg ataagactct ggacagccag
    10561 acaaaggctt acctggaggg gctgggcgta aagataaagc cttacgacga catctatgtg
    10621 cttgccaaaa ccttccgcaa cgagagaatc ctgctggaga agagccgcgt caatttcgct
    10681 gtctgccaga gtctggacga gagcaatgaa attgtaaatc agatgaatcc taccgcctcc
    10741 gccaaggcag tgaagaatcc tgtggagatg gagaatatga gaaaggccca catcaaggac
    10801 gctgtggcca tgatccgtca tctgcgctgg atgaaggaga atatcggtac gctggatatg
    10861 gacgagatgt ctgtccagag acatctggat cagctgagat tcgagacaga gggaaatctg
    10921 ggactgagct ttggaacgat ctctgcctat ggggagaacg cggctctctg ccattattcc
    10981 gccactccgg aaaccaataa gaagctggag ccaaggggac tttacctggt agattccggc
    11041 ggacagtatt acgagggaac gactgacatt accagaacca ttgccctggg gccggtgaca
    11101 gaggaggaga agaaatgctt cactctggtg gccgcctgca tgctgaggct tctgaacgtg
    11161 agattccctt acggctgcca cggctacaat tttgactttg ccgccagaga actgctctgg
    11221 agagaggggc ttgatttcaa tcacggaaca ggccatggag tgggatatct gttaaacgtc
    11281 cacgagcgtc caaacggcgt ccgctggaga gtcgttccgg agcgccagga caacgcagtg
    11341 tttgaggagg gcatggtgac ctctgacgag ccgggcctgt actttgaagg aaagttcgga
    11401 gtcagaacag aaaatctcat gctctgcgtg aaggacgtaa aaaatgagta cggccagttt
    11461 atgaaatttg aaaatctgac ctgggttcct attgacagag atgccattga taccagatgg
    11521 ctggagaaga gggatctgga gcttttaaat gagtaccaca gacaggtata cgaggtaatg
    11581 gctccccatc tctccgagga ggacagaagc tggctggaga aggcgacggc tcctatcgca
    11641 taagtggaag tggaaaaaca atagagtcca ggatccggga accgtttttt cagaaaccat
    11701 gtcatataca caaaaatcgg tttatatcat atagtaattc agaaggcaga tgtcagaaag
    11761 gcagatgtga tgagacagta tagaccagat ttgcaggtgt gcgagactgc cgccgaaagc
    11821 cgggggtatc ttcaggtaga cgtagtgaac gaggaaaata attttccagt gacagacgct
    11881 gtggtgacgg tgcaggagcc gggagagggc ggcagaattc tggaggagct tcctaccgat
    11941 cagtcgggac agacggagca gctggaatta gccgcccctg atatggctct cagcctggaa
    12001 agccagaata ccatccggcc ctacagcgta tataatctaa agatttcagc gccgggatat
    12061 gaggacgcgg aaatcacagg aaccgagatt ctgccgggag tgacggcgat tcagccggtg
    12121 cgcctgcggc cggtgaaggt ttctgcatca gagacagaga cggtccggat tccggggcat
    12181 acgctttatg agacgtatcc gcccaagatt gcggagacag aggtgaagcc ggtgcgggag
    12241 agcggggaga ttgtgctgag ccgtgtggtc gttccccaga cggtggtagt ccacgacgga
    12301 gttcccaccg acagaagcgc aaaagactac tatgtgcctt acagggacta cataaagaac
    12361 gtggccagca gcgagatcta cgctacctgg ccacagtctt ccattgtagc caatgtgctg
    12421 gccattatgt cctttaccct gaaccgcgtt tacacagagt ggtacaggaa tcaggggtat
    12481 gattttacga tcacctcctc cacagccttt gatcacaagt ggatttacgg aagagatatt
    12541 ttcgatacga tttctgtggt ggtggacgac atttttgaca gctatctgtc ccggccggac
    12601 gtaaagcagc cgattctcac ccagtactgc gacggaaaaa aggtcagctg ccctggctgg
    12661 atgacacagt ggggatcctg cgctctgggg gaacagggct acagccccat ggaaattctc
    12721 cgtaatttct atggaagcga tttgtatatc aatacagcgg agcagatttc aggaattccg
    12781 gcctcctatc ctggaacgga actgtccaca ggctccagag gggataaggt ccgccagctt
    12841 caggaacagc tggacgccat agccactgtc tatacggctg ttccgagcct gacgccggac
    12901 gggatttacg gaccggctac cgagcggtcg gtgaaggcgt ttcagtctat ttttggcctg
    12961 cctcagacag gaaccgtaga ttttgccacc tggtataaga tttcccacat ctatgtggcg
    13021 attaccagaa ttgccgagct gaacggataa tcagaaatag acacagacag ataaatcctt
    13081 acaatacgaa aaggggagaa ggtatgaatg ccatggcaaa agagcggaat gcgggaaaga
    13141 agggaaaaca gggaaatggc ataacagagg gagtcatctg gaagcagctc ctcatttttt
    13201 tctttcctat tttatttggt acgttttttc agcagcttta caacacagta gacgcagtga
    13261 ttgtaggccg gtttgtggga aaagaagcgc tggcggcggt aggaggaagc acgggaacgc
    13321 tgattaatct tttagtcggc ttctttgtgg gcctctcctc cggcgcgacg gttattatct
    13381 cccagtttta cgggggagga agagaaaaga gagtcagcga ggctgttcac acggcgatcg
    13441 ccttctctct ggcctgcgga gtaggactta tggtcattgg aatcgccgcc tcccccatag
    13501 ccctgcgggc catgggaacg ccggatgata ttatgcagta ttccctgtcc tacatcagaa
    13561 tttattttct gggaattatt ccaaacctgg tttacaacat gggagccggt attttaaggg
    13621 caatcggaga ttccaagcgg cctctatact acctgatggc cagctgcttt accaatattg
    13681 tgctggatct ggtgctggtt gtctggcttc ggctggatgt gcggggagcg gcgattgcga
    13741 cgattgtgtc ccagcttgtc agcgcagttt tggttgtgct ccagcttctt cgcacaaagg
    13801 attcctacag gctggtgatt cgaaagatcc gtctgaatct gttcatggta atgcgtattg
    13861 tgcggattgg cctgccggct ggcctccagt ccgtgatgta ctctgcctcc aacatcatta
    13921 tccagagcag cgtaaactct ctgggaacag acacagtggc agcgtggacg gcttacagta
    13981 aaatcgacag cgtttactgg atgattatca gtgctctggg tatttccatc actacgtttg
    14041 tagggcagaa ttacggcgcg ggaaaactgg accgggtaaa gcggggaatt tatgtgtgtc
    14101 tgggactcag cttcctcatt acggctattt taagtgtaac cctgtacctg ggaggcggct
    14161 atatttatct catgtttacg gcagatgcgg cggtaatagc caagggaatg gaaattcttc
    14221 atttcctggt tccggccttc gccacctatg tgtgtatcga ggttctttcc ggcgcgctga
    14281 gaggcacagg ggactgctgg attcccatga ttatgacggc agtaggagtg tgcgccctga
    14341 gagtcctctg gatccttgtg gcggttccgc tgaagccgga catccttact gtggtgttca
    14401 gctatccgct tacctggagt attacaagta ttttattcct ggtgtatttc tactgcttca
    14461 gttctctgaa gaaattcaat gttcctcttc cgaggctgcg gcgcagaaga aaacatgctg
    14521 gagcagtata aaaagaaagg aacggtgtgt atggagtaca attctatgaa ccagtgggga
    14581 gaaatccagg ccagccaaag agagagcctg tcagcgtata cggcgaagac gtttctctgg
    14641 atgtttgccg gccttctcgt tacctttgcc atgacctatg ccagctatgc cacaggcctt
    14701 gtgcttttag tattttcaaa cagctatgga atcctgatgc tgacaggagc agagcttttg
    14761 gtagtgattt ttatgtcagc cagagtccac aagatttctg tgggaacagc cagagccatg
    14821 tttctgctgt attcagcttt aaacggggtg gtattttccg cttacttcct gataataggt
    14881 tccggcatgc tgatgtttat ttttggggct acggcagtct ttttcggact gatggccgga
    14941 gtatcctaca ttgccagggt tgatctgtca ggaatccgcc ccctcttaat aggcggactg
    15001 attttcctcg tggtattcca gtttctggcc atgtttttaa acctgacttc catggaaacg
    15061 atcatgtgct atgtgggaat cctgatcttt ctggggctga ctgcctacga tgtgggcatg
    15121 atccgcagaa attatcagat gttttccgga aatgaggaat tattagccaa ggcgtctatc
    15181 ttctcagcgc tggagctgta cctggacttt atcaatatat tcctgtatct tttaagactg
    15241 tttgcaagga acagagatta aggataaaaa tgggatccct gccttcgctt ttttggcgga
    15301 tgcagagatc ccattttcat ttcataggaa aaagcgtcct attaaatttc tgtttaaatt
    15361 tctgttttca tgaattgctt gtcaaattct gggttaaaat aataataatt tttcctgtcc
    15421 agagaatcct tcagctgttc cagcgcttca ccaaaccgct ggaaatggac aatctccctg
    15481 gcgcggagaa accggagagg agcttttacg tccggatccg tgatgacacg cagcagattg
    15541 tcgtaggtgg tccgggcttt ctgttccgca gacagatcct ccgtcaaatc ggtgatggcg
    15601 tctcccttgc tctgaaattc gcaggcgtta aaaggaactc ctccggccga ctggggccac
    15661 agagcggcgg tatggtcgat atagtaggcg tcgaaaccgg cagttctggc gtcctcaggc
    15721 ttcatattcc ttgtaagctg aaagatgatg gaacagataa tctcaagatg agccagctcc
    15781 tctgttccga tatctgtcaa aagtccgctg attttccggc agggcatgga atatctctgg
    15841 gagaggtaac gcatggaagc ggccagctcc ccgtcagggc cgccgaattg gctgataatc
    15901 agctgggccg ttttcggaca gactgtttta atgttgacag gaaactggag acgtttttca
    15961 taggtccaca tttaaatcat tcctccttcc cagggcgcgg gtccgtcctg aagactccag
    16021 cggtctgcgc cgcccagatc gcagacgcag ccggcagtca acgggccgta ggctttggca
    16081 tactggttca taagctcctt ccgtctggcc gcttccttct gaaagcgggc caggccttcc
    16141 tggcagtctg gatgggtatc caggtagagc gttaaatcat tgactgcaaa gctcaccttg
    16201 tcaatctcgt gaagaagggc agagcggctt ggcgtttctg cattacctaa cataggcgtc
    16261 acctcctgcg aaaaaaggca tatcgaggga agggaacaga cagccgtgca gcagagcggt
    16321 ttccaaatcc tgaggctcct cccaggactg gcgtgggaca gaagcaatcg ccagatccag
    16381 gcggcaggag cagccgcaat ccagctgatc atcatttact gtagtcatag acagacactt
    16441 cctttctgtt ggtatcgtgg cagccaggcg gtttaaatgc cgcgcgtgaa ctgcctgctt
    16501 ttagtatgag ccgctttggc gcaggatatt tctaaaaaag aatccgccag atctgcggaa
    16561 aaattccagt gcaggaagga tattatgatt gtgtgaatat tagagcattt catacaataa
    16621 aacttgcaat ttatgcaata agcatataca atataagcta ggcaaaattg ggactgcaaa
    16681 agtatctctt ttactaagca taccaagtca aactaattca aatggaggac tgcaaaatga
    16741 gtaattcagc gaacacatca gcaggtaaaa gaattgaagc tttacttgat gataacagtt
    16801 ttgttgaagt tggagcttat gtgaaggcaa gaagcaccga ctttaacatg gcggcgcaga
    16861 ataccgccgc tgacggcgta atcaccggtt acggcacgat tgagggaaat ctggtgtatg
    16921 tatacagcca ggacgcttct gttatgggag gttctgtggg agagatgcat gcgaagaaaa
    16981 tttccaacgt ataccggatg gctatgaaaa tgggagctcc tgtgattggc ctggtagact
    17041 gctctggttt aaggcttcag gaggcgacag acgctctgga cggttttgga cagatgtatc
    17101 tgaatcaaac catggcttcc ggcgtagttc cgcagatctg cgcggtattt ggaagctgcg
    17161 gaggcggcat ggctgtttcc tctgcgattg cagatttcgt tttcatggaa gagaaagcaa
    17221 agatgtttgt caattctcca aacgctctcg ctggaaatga tgagaaaaag tgcgataccg
    17281 cttcagcaga tttccagagc ggcgaatcag gactggctga cgtggtggga agcgcggagg
    17341 agattcttgc gaaggttcgg actctcgtct ctgttcttcc ggctaacaat gaggacgaca
    17401 tgtcctatga cgagtgcggc gacgatttaa accgcctctg tgaaaatatc gagagcttca
    17461 ggggagacac aggaaaggcc ctttccatga tttccgacga cggcttcttc tttgaggtga
    17521 aggaaaacta cggcccggag atggtaactg cctttatccg cctgaacggt atgacggtag
    17581 gatgcgtagc caaccgcaca gaagtattgg atgaggagaa tgagaagact gcagagtatg
    17641 agccggttct tggagcaaga ggctgcgata aggcggcaga gttcgtttct ttctgcgacg
    17701 cctttaatat tccggttctg gcccttgtaa acgtaaaggg ctacaagcag tccaagtgca
    17761 cagagagaag aatcgcaaag gctgcaggac gcctgaccta tgcgtttgcc aatgcagacg
    17821 tgccgaaggt aacggttgtg attggagagg cttatggaag cgcttatgtg accatgaaca
    17881 gcaagtccat tggcgcggac atcgtatacg catggccgga tgcaaaaatc ggcatgatgg
    17941 atgcagcggc agcagtgaag atcatgtatg cagaggagat cagcgcttct gacaaagcgg
    18001 ctgccttgat ttcagagaag gcggcagagt atgaggctct ccagtccagc gcggcggcag
    18061 cggcaggaag aggctatgtg gacgatatta tcaaggcaga cgagacgaga cagcgcgtaa
    18121 ttgccgcatt cgagatgtta tttacgaaaa gagagggacg tccatccagg aagcatggca
    18181 cagtctaagg cgaggtgaca agatatgaaa cagaatatga aacggctgct tctcctgtta
    18241 tccatgataa cctgcttctt tgttctgtcc ggctgtgcaa aaacagagga ttccggttca
    18301 gaagaggtta cagccgagat ggaggagact ctggtgaacg gctccaggca gtatctggct
    18361 gcatttgcag cttacagcga cgaggagctg gaggagcaga tcaagcaggc agaaaaggca
    18421 gagaatactg tgatttccac agccctcagc tcctggaaat ctgtaaagga agatctggga
    18481 agtctccagg tagacgagat gggagctcct ctgatccaga cagatgaaaa aactggaaag
    18541 ccggctgtta cagtacaggc ggaaggcgag gatatttatc aggtagaact gactgccgtt
    18601 tatgagcaga gaaccatgga gtttgttctg actgccaagg cggaggacga cggttacggc
    18661 ggcagcgttc tgactgtaac agagatgaca tttactcctg attattccat aggagagaag
    18721 ctgcagaagg ctttcttaaa tatgcttatg ggtatgggaa ctgtatttgt tgtgcttctt
    18781 ttcatcagct ttattatcag ccgtctgaag atggtaaaca gctggggtgc gaagaaggaa
    18841 gataaaacgg caaaagagag cgctccggcc ccagttccgg caaagccggc agctccagtt
    18901 ccagcaccgg cggcaccagc accagcggca gctcctgcgc cggccctggt acagcttgag
    18961 gagagctgtg aagaaaatct ggcagacgat atggaattag tagcagtaat tacagccgca
    19021 atttcggcag ctcagaaggt tccggcagaa ggacttgtcg ttcgttctat ccgcagaaaa
    19081 tcaggctcta attggaagag agcttaacga gaaagaataa accaggagga aagaatcatg
    19141 aaaaattata caattacagt aaatggaaat gtttatgaag taacagtaga ggagggcttt
    19201 acaggaaagg cttccgcacc ggcagcaaga ccggcagctc cagcaccggc ggcaccagct
    19261 cctgcaccag ccccggcagc cccggcagcc ccggctcccg caccagcccc agcagccccg
    19321 gctccagcag ctgcaccggc agcaggctcc attacagtca gcgcgcccat gcctggcaag
    19381 attctcggcg tgaagacgtc cgtaggagca gctgttaaga aaggacaggt aatcctgatt
    19441 cttgaggcta tgaagatgga gaacgagatt gtagctccgg aggacggaac ggttgcgagc
    19501 gtcaacgtat cagtaggcga gatggtagag ccaggagcga cacttgcgac tttaaactaa
    19561 tgaatgcgta aatccgtttg gagggataaa catggaatat ataacatcaa cattgtccaa
    19621 tcttcttcac cagacagcat tctttaatct gacctttgga aacctgatca tgattttagt
    19681 ggcctttgtg ttccttttcc tggctatcaa aaaaggattt gagccgcttc tgttagttcc
    19741 gatttccttc ggtatgctgc ttgtaaatat ctatccggat attatgatgt cgattgaaga
    19801 gtcgtccaat ggagtgggag gacttctcca ctatttttac ctgttagacg agtggagtat
    19861 tctgccttcc ctgattttca tgggcgtagg cgcgatgact gactttggcc ccctgattgc
    19921 caacccgtcc agcttccttt taggagctgc ggctcagttc ggtatttatg ccgcttattt
    19981 cctggccatc tttatgggat tcaatgacaa agctgccgca gctatctcca tcatcggagg
    20041 agcagacggc cctacttcta ttttcctggc tggaaagctg ggacagacag gcctgatggg
    20101 accgattgcc gttgccgcat actcctacat ggctctggtg ccgattatcc agccgccgat
    20161 tatgaagctc ttcaccacag aggaggagag aaagatcaag atggagcagc tccgtccggt
    20221 ttccaagctg gagaagatcc tgttcccaat cgttgtaaca gtagtcgtat gtctgattct
    20281 tcccacaaca gctcctctgg taggcatgct gatgctcgga aacctgttca gagagtgcgg
    20341 cgtagtaaaa cagctcacag agacggcttc caacgcgtta atgtacattg tagttatttt
    20401 cctgggaacc tccgtaggcg cgactaccag cgcagaggct ttcttaaacc tggatacaat
    20461 caagattgtt gttctgggac tggtagcctt tgccttcgga acggcagcag gagttttatt
    20521 tggaaagctt atgtgcaagg caacgcatgg cagggtgaat ccgctgattg gttcggcagg
    20581 cgtatccgct gttccgatgg ctgcccgcgt atctcagaag gtaggagctg aagcagatcc
    20641 gaccaacttc cttctgatgc acgctatggg accgaacgtg gcgggagtaa tcggtactgc
    20701 cgtagcggcc ggaaccttta tggcgatctt tggaatccag taaaatttag aggaggaaat
    20761 gacgatggca aagatagaga aaaagccggt taagattgtg gagactgtcc tgcgggacgc
    20821 ccaccagtct ttgatcgcga cgaggatgac gacggagcag atgctcccga ttattgataa
    20881 gatggataag gtaggctacc acgctgtcga gtgctggggc ggagctacct ttgacgcttc
    20941 tctgcgcttc ttaaaggaag atccatggga gagactgaga aagctgagag acggatttaa
    21001 gaacacaaag ctccagatgc tgttcagagg acagaatatt cttggctata atcactatgc
    21061 tgacgacgta gtggaatatt tcgttcagaa atccatcgca
//
LOCUS       DBMDUW010000044        20248 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1633_length_20248_cov_6.010374, whole genome shotgun sequence.
ACCESSION   DBMDUW010000044 DBMDUW010000000
VERSION     DBMDUW010000044.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 20248)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 20248)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20248
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1633_length_20248_cov_6.010374"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(63..500)
                     /locus_tag="ACZPCR_08835"
     CDS             complement(63..500)
                     /locus_tag="ACZPCR_08835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007884694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM mobile pair system MarR family
                     transcriptional regulator"
                     /protein_id="HIR1231016.1"
                     /translation="MEMNGGFLVTKIKQLGDRIFEKILSEKNIDAFNGAQGRILYVLW
                     QEDGISIRSLSTKCGLAITSLTTMLERMENQGLISRVQSETDKRKTLLFLTEKAHALK
                     GEYDSVSDEMGSIYYKGFSEEEITRFEECLDRIRKNLEEWQKS"
     gene            complement(1039..3042)
                     /locus_tag="ACZPCR_08840"
     CDS             complement(1039..3042)
                     /locus_tag="ACZPCR_08840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008396387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HIR1231017.1"
                     /translation="MAGSFSGRSSRRGRLRKFFQDFYLVIILIFLYAPIVTMMILSFN
                     DSKSRTLWGGFTTKWYTQMFESPAIMEALYNTLLIAFISALAATILGTLAAIGISSMK
                     RTPKNIVMGINNIPILNSEIVTGISLMLTFIAFGISLGFKTILIAHITFNLPFVILSV
                     MPKLKQTSRYTYEAALDLGAGPLQAFFKVVFPDILPGVLSGFLMGFTMSLDDFIITHF
                     TRGAGINTLSTLIYSEVRRGIKPSMYALSTIIFVTVLALLLITNFAPRDDAAKAGSKR
                     AGRPETGGKQNDNEMAGKKRIGLILRGPGFKKGLLAAASFAIVCTVCAATYIRYASQS
                     SNELYVYNWGEYIDESVIEEFEEETGIDVIYDLFETNEEMYPVVEAGGVAYDVVCPSD
                     YMIQKMAENGMLAEINYDNIPNIKNIDPEYMEKAESFDPGNRYAVPYTWGTVGILYNT
                     KRVEELGLNPPAKWADLWNPAYQGEILMQDSVRDAFMVALKSLGYSLNSTSEAELKEA
                     RDLLIAQKPLVQAYVIDQVRDKMIGGEAAAGVIYSGEMLFIQEEAARQNLDYQLEYVI
                     PEEGTNIWIDAWVIPKNAKNKENAEKWINFLCRPDIAKKNFEYITYATPNRAAKELLD
                     PELQNNKALFPDTDELKHSEVFQYLGDEVDMIYNRLWKEVKSE"
     gene            complement(3069..3902)
                     /locus_tag="ACZPCR_08845"
     CDS             complement(3069..3902)
                     /locus_tag="ACZPCR_08845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007862127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1231018.1"
                     /translation="MNSVSKKNMKQYLAGPYLIWMTGFTIIPLLLIAWYGLTDAGGAF
                     TLENIAAIATQEHSKALFLSLGLSLLSTVICLLLAYPLAMILRKKHIGKGSFIVFIFI
                     LPMWMNFLLRTLAWQTLLEKNGVINGILSTLGLPGISIINTPAAIVLGMVYNFLPFMV
                     LPVYNVLVKIDDNTINAAKDLGANEFQTFIHVWLPLSLPGIVSGVTMVFVPALTTFVI
                     SNLLGGSKILLIGNVIEQEFTKGSNWHLGSGLSLVLMVFILISMALIAKYDKNGEGTA
                     F"
     gene            complement(3895..4971)
                     /gene="potA"
                     /locus_tag="ACZPCR_08850"
     CDS             complement(3895..4971)
                     /gene="potA"
                     /locus_tag="ACZPCR_08850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:1902047 - polyamine transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     ATP-binding protein"
                     /protein_id="HIR1231019.1"
                     /translation="MSQPFIDLVNITKSFDGSIVLDDLCLSVKENEFVTLLGPSGCGK
                     TTTLRIIGGFESPDRGKVLFSGKDITSLPPNKRQLNTVFQKYALFPHMSIAENIAFGL
                     KIKKKPKSYIDDKIRYALKLVNLDGFENRSVDSLSGGQQQRIAIARAIVNEPKVLLLD
                     EPLGALDLKLRQDMQYELIRLKNELGITFIYVTHDQEEALTMSDTIVVMNQGYIQQMG
                     SPEQIYNEPENAFVADFIGESNILDGIMLHDGLVEIAGAKFACVDKGFGCKTPVDVVI
                     RPEDIDLVKPEEGTLQGVVTHLIFKGVHYEMEVTTPDGWEWLVHSTDLFPVGEKVGIH
                     VDPFDIQIMNKPASEDEEAVGIDE"
     gene            complement(5024..5557)
                     /locus_tag="ACZPCR_08855"
     CDS             complement(5024..5557)
                     /locus_tag="ACZPCR_08855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1231020.1"
                     /translation="MSIGSKLKALRILKGLTQEELADRAELSKGFISQLERDLTSPSI
                     ATLMDILQCLGTTIGEFFAETADEQIVFGKQDFFTKTDAELKNTIQWIVPNAQKNCME
                     PILLTLEPGGSTCPDTPHEGEELGYLLSGSILIHIGTSIYKAKKGESFYFTSAQTHYI
                     ETEDGASLLWISSPPSF"
     gene            5908..6969
                     /locus_tag="ACZPCR_08860"
     CDS             5908..6969
                     /locus_tag="ACZPCR_08860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HIR1231021.1"
                     /translation="MAGKYMAYVGSYSYNGQAKGITVYDVDVENGYFKYRCEVEVDNS
                     SYLAVSHDGKTLYSIADEGVVSFRILPNGGLTRLNSAGIKGMRGCHLATDAEDKYIFV
                     SGYHDGKETILRLNPDGTVGEITDKVFHKGLGSVAERNFRPHVSCAGRTPDGEFLMAA
                     DLGIDQVKIYGFDSEKGTISQVDAVRCELESAPRQFVFSKDGRFFYLMYQLKNAIDVY
                     SYEYEPGERVPKIERLQTVSSTDTPAGELTAACAIRMSPDDRYLFCSNAGDNCVSIYE
                     RDPDTGLLTMKCCLPISGDYPKDIAIFPDQKHMASINHASGTISFFSIDYENGLLMMN
                     HRSIDVNEPNCCVITKIPE"
     gene            6997..8106
                     /gene="aroC"
                     /locus_tag="ACZPCR_08865"
     CDS             6997..8106
                     /gene="aroC"
                     /locus_tag="ACZPCR_08865"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007719655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HIR1231022.1"
                     /translation="MAGSTFGTILRMTTWGESHGPALGVTVDGCPAGLELCEADVQEY
                     LDRRKPGQGKYSTKRNEGDQVEILSGVFEGKTTGTPISMMVRNRDQRSRDYGEIASCY
                     RPGHADYTFDQKYGFRDYRGGGRSSGRETIGRTAAGAVAAKLLKELGITVTAYVSQIG
                     PVRIAPERFDLQAARENRLCMPDSQASEEAEQFLDGKMAERDSAGGVVECRINGMPAG
                     IGEPVFDKLSANLARAICSIGAVKGFEIGDGFAAASSVGSENNDAFGLDQSGHIVKQT
                     NHSGGILGGISDGSEIIFRAAFKPTPSIAAPQRTVNSRGEETELEIKGRHDPIIVPRA
                     VVVVEAMAAFTAADMMLLNMGARVDKIREFYQKQR"
     gene            8319..8921
                     /locus_tag="ACZPCR_08870"
     CDS             8319..8921
                     /locus_tag="ACZPCR_08870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003509861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HIR1231023.1"
                     /translation="MEERRTDIIGPGVADEAADKAEVERIRGQVRQLLGEFFEAAGMK
                     RGQILVVGCSSSEIESHRIGSYSSREIGQAVFEEIYQETQKRGIYLAAQCCEHLNRAL
                     IVEEECAEKYGLEQVNVVPQLKAGGSFATAAFSAFENPAAVERIQAHGGIDIGDTFIG
                     MHLRPVAVPVRTSVREIGSAHVTCARTRLKCIGGERAAYR"
     gene            9040..10458
                     /gene="rlmD"
                     /locus_tag="ACZPCR_08875"
     CDS             9040..10458
                     /gene="rlmD"
                     /locus_tag="ACZPCR_08875"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013274512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0000154 - rRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HIR1231024.1"
                     /translation="MKKNDRFVLKIEDMGENGEGIGRLDGYIWFVKDAVIGDVIEAGV
                     TKMKKQYGFARLIRVIEPSEYRTEERCPSARRCGGCQIQAVDYQEQLRLKEKKVYNNL
                     KRIGGLSSLLLPGGEETTEQTKEETERNAVVMEPIIGMENPWRYRNKAQFPFGRNKDG
                     RIVTGFYAGRTHDIVEQEDCLLGVEENREILSIIRNFMEEYKIEPYNEETHRGLVRHV
                     LIRKGFQTGELMVCLVINGRKLPGQQALTERLLEIPGMTSISLNVNQEKTNVILGKEL
                     INLWGEGHITDYIGAVQYRISPLSFYQVNPVQTERLYGTALEYAGLTGNETVWDLYCG
                     IGTISLFLAQKAKQVYGVEIVPQAIDDARENARLNHMENVEFFVGKAEEVLPEQYERN
                     QIYADVIVVDPPRKGCDEKCLETIVKMSPKRVVYVSCNSSTLARDVKYLEERGYRTER
                     VRCVDMFPHSGHVETVVKLKKW"
     gene            10553..11074
                     /locus_tag="ACZPCR_08880"
     CDS             10553..11074
                     /locus_tag="ACZPCR_08880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007591280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HIR1231025.1"
                     /translation="MNSITIREALAEDASQLIEYMKTVGAETENLSFGGEGLPVSIEQ
                     EAAFLEAVRQEKTSVHLAAFKDGEIIGDGSLTGLPRRMSHRAELGLSVKKAYWNQGVG
                     SALMRRLIQYAEENGIELLSLEVRSDNIRAVRLYESFGFQRIGTSPAYFKIDGRYADF
                     ELMYLDLRKGGQI"
     gene            11249..11443
                     /locus_tag="ACZPCR_08885"
     CDS             11249..11443
                     /locus_tag="ACZPCR_08885"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231026.1"
                     /translation="MRAILKSFHRIEETFDRKAEAFALRHPFLAFWVMFVGMPVMLLL
                     TVSLSTMVLVMPFHYLWGWC"
     gene            11665..11742
                     /gene="kdpF"
                     /locus_tag="ACZPCR_08890"
     CDS             11665..11742
                     /gene="kdpF"
                     /locus_tag="ACZPCR_08890"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031004 - potassium ion-transporting
                     ATPase complex [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA];
                     GO_process: GO:0043462 - regulation of ATP-dependent
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HIR1231027.1"
                     /translation="MAVLGLMIAALGAYLVYALVNPEKL"
     gene            11808..13502
                     /gene="kdpA"
                     /locus_tag="ACZPCR_08895"
     CDS             11808..13502
                     /gene="kdpA"
                     /locus_tag="ACZPCR_08895"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031004 - potassium ion-transporting
                     ATPase complex [Evidence IEA];
                     GO_function: GO:0008556 - P-type potassium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HIR1231028.1"
                     /translation="MLQIVLTLAIFVILVIPTGRYMYHIASNQKTFADPVFDPVDKVI
                     YRVCGIQGGDMGWKKYTLSLLMANGVMVFTGYLILRLQGLLFFNPNGIGSMEESLSFN
                     TIISFMTNTNLQHYSGESGLSYAGQMCVIIFMMFTSAASGYAACMAFCRGLAGRPLGN
                     FYRDMVRITTRILIPAAFLTGLLLVGQGTPQTLAGNLTVETIEGKFQDIAVGPVAALE
                     SIKHLGTNGGGFFGANSSTPFENPTVISNMVEMISMMLLPGSCVVTFGLMLHDRKDGK
                     KPLFGRQGAVIFGAMAIIFLIGLAVCFSAERAGNPVVSAMGLSQDMGSMEGKETRFGM
                     EQSALFTTVTTSFTTGTVNNMHDSLTPLGGLVPLLHMMLNCVFGGKGVGLMNMVMYVI
                     LAVFICGLMVGRTPEYLNKKIEGKEMKLVAIVILIHPLLILGFSALAVSVQGGLSGIT
                     NPGFHGLTQVLYEYASSAANNGSGFEGLADNSLFWNVTTGLAMFFGRYLAIAAQLAVA
                     GSMLAKRKVNESVGTLRTDNTTFMIVLVFIVYIFAALTFFPALALGPVAEHLSLWM"
     gene            13539..15593
                     /gene="kdpB"
                     /locus_tag="ACZPCR_08900"
     CDS             13539..15593
                     /gene="kdpB"
                     /locus_tag="ACZPCR_08900"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009244327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0031004 - potassium ion-transporting
                     ATPase complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008556 - P-type potassium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HIR1231029.1"
                     /translation="MAKKQGAKFVTPDILKSSVIGAFKKLDPRYMVKNPVMFVVEAGC
                     FVTLLLTFCPTLFGGQAEYQIYNGIVTAVLFVTILFANFAESVAEGRGKAQAESLKKT
                     KQDTKARLLLPGGGEKMINASDLKKGDIVLVKLGEVIPNDGEVIEGIASVDESAITGE
                     SAPVTREAGGDFSSVTGGTTVVSDWLKIRIAAEPGHSFLDKMISLVEGASRQKTPNEI
                     ALNTLLIVLTLIFLIVVVTLYPFAAYLGVEIPVSWAIALMVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLAAEFYPVNGVEKEDLID
                     YSVMSSLMDGTPEGKSTVDLGRRMGCVLTEEAAGQMNFIEFTAQTKMSGVDLQDGTVV
                     RKGASEAVKRFVEEKGGSIPADLEEIVTKVSNLGGTPLTVCVNDKILGVIYLKDTVKP
                     GLSERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECRPEDKIEAIKKEQAE
                     GKLVAMTGDGTNDAPALAQADVGLAMNSGTQAAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGSLTTFSVANDIAKYFAIIPAMFTMVLPQMQILNIMRLATPASAILSALIFNA
                     LIIPGLIPIAMRGVKYKPMKAEKLLLRNMGIYGLGGMIVPFVGIKLIDLVTAPMLSAI
                     GM"
     gene            15606..16250
                     /gene="kdpC"
                     /locus_tag="ACZPCR_08905"
     CDS             15606..16250
                     /gene="kdpC"
                     /locus_tag="ACZPCR_08905"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004611238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008556 - P-type potassium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpC"
                     /protein_id="HIR1231030.1"
                     /translation="MKGFLKMFRTAFVFCIVMMLLCSFAYPLALTGASQAVMKEKAGG
                     SLIDREGNLTDDPEKAVGSVLLGQDFTEDYFFHGRVSSVHYNTYTEEQKESGEYGGVS
                     SGSFNYGNSSPDLEARIKKDLDSFLASHPGVKAEDVPADLLTASGSGLDPHISPEAAR
                     VQIPAVAEHSGLSEEEISRIVEENTEGKALGVFGEERVNVLKCNLAIARAMGLI"
     gene            16281..18320
                     /locus_tag="ACZPCR_08910"
     CDS             16281..18320
                     /locus_tag="ACZPCR_08910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009266171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HIR1231031.1"
                     /translation="MPGMKEEGGGGKAMQEERPDSEQLLKRLKYEEREQKKRTRGRLK
                     IFLGYAAGSGKTYAMLEAAHEAKAHGIDVAAGYIEPHDRPDTQALTKGLEMLPPAFME
                     YKGMKLREFDLDGALKRKPQLLLVDELAHTNCRGCRNEKRYQDVKELLRAGISVYTTL
                     NIQHLESLNDLVGSITHIDVRERIPDTVFDHADQVEVVDIEPEDLIERMKEGKIYRKE
                     QADRALQNFFRRERLAALREIALRRCADRVNRIAEEERSLLERQDYHTGEHILVCITA
                     APSSAKVIRTASRLADAFHGTLTGLCVETPDTQEAGEKTKEALRNNMELAKLLGAKIV
                     TVFGSDVAAQIAQYAIVSNVSKIVLGRTNHFTMRPMYRSELLEKLTYMAPNIDIYIIP
                     DMRQTKRWHPRQSAAKRQESWKKCAAGLAAATAVMLAATALALILRMFVFSEANTIMI
                     YMMGVLLASCAASRKLCALYSALLSVILFNFFFTEPLYSLKAYDQAYPITFLMLFLAG
                     LFTATVTGKLKRQNVESSKTAYRTGILLENSQKLRRCKTREDVWRQAAVQAGKLLNLS
                     ILFYPVRKDGAVEEPLLFPRKGMDPEELKRCVNAQEKGVAQWTASNRRRAGACTHTLP
                     DAMAMYLPVQDEEQIHAVMGIFLEERRPVAEFEYSLLTAMLNETGVKLKDFFIQS"
     gene            18442..19089
                     /locus_tag="ACZPCR_08915"
     CDS             18442..19089
                     /locus_tag="ACZPCR_08915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005330390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HIR1231032.1"
                     /translation="MKSILLIGLGRFGRHIARKLSELRHEVMAVDIDEKRVEAMLPYV
                     TNAQIGDATDEDFIRSLGVRNYDVCMVAIGDNFQSSLETTSLLKEMGAALVVSRASRD
                     RQKKFLLKNGADVVIYPERQLGEWTAMRYSSDHIFDYVELDGEHAIFEVSIPREWFGK
                     TIGQIDVRNKYNINIMALKHNGVMQLNITSDTLLSFEYTMLVLGRIKDVQKCFHI"
     gene            19141..>20248
                     /locus_tag="ACZPCR_08920"
     CDS             19141..>20248
                     /locus_tag="ACZPCR_08920"
                     /inference="COORDINATES: protein motif:HMM:NF014728.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor protein KdpD"
                     /protein_id="HIR1231033.1"
                     /translation="MAKERGRLKIFFGYAAGVGKTYAMLQAALAAREKGIDVVIGSVS
                     PHTMPETAALADTLEQLGGDGRRAVGEFDLDAAILRSPQLILVDELARANPEGCRHAR
                     RYQDVEELLKAGIDVYTTVNAQNIESLSDIAATIMKHSIKDRIPDDVFDRADQVELID
                     IEPQELMERLKCGTIDEKQGKNPPAEAYFSIENLTALREIALRRCADRINRSGDRRGT
                     DRGEDLFAEEHILVCLSAAPSNARIVRTAARMAQVFHGSFTALFVKTPEFTRWDEESL
                     QRLQENIRLAEQLGADIQVIYSNDIPFQIAEFARLSRVTKIVMGRSAAARSHFFGRPA
                     LTEKLILNAPNLDVYIIPDAVSEKARYRAKKSGRS"
BASE COUNT         5098 a         4672 c         5833 g         4645 t
ORIGIN      
        1 acaccccact gtgcagccaa tgacgatatt catgttctga atctgatctt tgatacaaat
       61 actcatgact tctgccactc ctcaagattc tttctgatgc ggtcgaggca ttcctcaaac
      121 cgggtaattt cttcctctga aaaacctttg tagtaaatac tgcccatctc atcagataca
      181 gaatcgtact cgccctttaa ggcatgtgct ttctcagtca gaaacaggag tgttttcctt
      241 ttgtccgttt cagactgaac acggcttatc agcccttgat tttccattct ttccagcatc
      301 gtagtaagag atgttatcgc taatccgcat ttagtcgaga gtgacctgat tgagatacca
      361 tcctcctgcc acagcacata aagaatacgt ccctgggctc cattaaacgc atcaatattc
      421 ttttcactga gaatcttctc gaaaatccgg tctccaagct gttttatttt ggtgacaaga
      481 aatcctccat tcatttccat gcaaaagctc ctatatagta gtttattaaa aacatactat
      541 ataggagttt tattgtcaag agtttatatg tcttaatagg taaattccgt tttttcaatt
      601 cttcaaactg cgatttgtcc gtttctttat ccctatatta taacagttgt acatattcgc
      661 aacaacaaaa atgaacatac atcttggcat tttgctgtct ttcccaataa gagctgcaaa
      721 aaaagggatg ttttccagtg actttaggtg gaacgaggaa aacatccctt ttttgattcg
      781 cgtctaccac aaacctacct gagaaaagga gaagatttcc ggtgacttta agtggaacga
      841 agaaaacatc ccttttttgg ttcatccttc taccgcaaac ccgcttaaga aaaggagaag
      901 atttccggtg actttaagcg gaacgaggaa ctcctccctt tttcttgatt cgcgtctacc
      961 gcaaacccac ttaagaaaag gagaagattt ctggtgactt taagtggaac aaggaaatct
     1021 tctccttttc ttcaccccct actctgactt cacttccttc cacaaacggt tgtatatcat
     1081 atcgacttcg tctcccagat actgaaagac ctcggaatgt ttcagctcgt ctgtgtcggg
     1141 gaacagagcc ttattgttct gaagctctgg atccagcagc tccttggcag cccggttggg
     1201 ggtggcgtag gtaatgtact cgaagttttt ctttgcaatg tcagggcggc agaggaaatt
     1261 gatccatttt tctgcatttt ctttattttt cgcgtttttc ggaattaccc aggcatcaat
     1321 ccagatattt gtgccctcct cggggattac gtattccagc tgatagtcca gattctgtct
     1381 ggcggcctcc tcctggataa agagcatctc gccggagtag atgacgcctg cggccgcctc
     1441 cccgccgatc atcttgtctc tgacttgatc aatcacatag gcctgtacca gaggcttctg
     1501 ggcaatcaga agatctctgg cctccttcag ttcagcctcg ctggtggagt ttaaggagta
     1561 tcccagagat ttgagggcca ccatgaaggc gtccctgacg ctgtcctgca tgaggatttc
     1621 cccctggtag gccggattcc acagatcggc ccacttggca ggaggattca gccccagctc
     1681 ctccacccgc ttcgtattgt agaggatgcc tactgtaccc caggtgtagg gaaccgcgta
     1741 ccggttgcca ggatcaaagc tctcggcttt ttccatatat tccggatcaa tatttttaat
     1801 attcggtatg ttatcgtagt taatttcggc cagcatgccg ttttccgcca ttttctgaat
     1861 catgtagtca gagggacaga ccacgtcata ggcgacgccg cccgcttcca ccaccggata
     1921 catttcttcg ttggtttcaa acagatcgta gatcacgtca atgccggttt cctcctcgaa
     1981 ttcctctatc acagattcat caatgtactc gccccagttg tagacgtaga gctcgttgga
     2041 ggactgggag gcatagcgga tataggtggc ggcgcagacg gtgcacacga tggcaaagga
     2101 agccgcagcc agaagtcctt ttttaaagcc aggtccccgc agaatcaggc cgattctttt
     2161 tttgccggcc atctcattgt cattttgttt cccgcctgtc tctggccttc cggcccgttt
     2221 gctgcccgcc ttggccgcat cgtccctggg ggcgaaattt gtgattaaca ggagggccag
     2281 cactgtcaca aagataatgg tggacagagc gtacatggag ggcttgatgc cgcggcgcac
     2341 ctcgctgtaa atcagcgtgg acagcgtatt gatacctgcg cccctggtaa agtgagtgat
     2401 aataaaatcg tccagggaca tggtaaagcc catcagaaag ccggacagca cgcccggaag
     2461 gatatccgga aacacaacct tgaaaaacgc ctggagaggt cctgcgccca gatccagggc
     2521 cgcctcgtag gtatagcggc tggtctgctt aagcttcggc ataacgctca aaatgacaaa
     2581 gggcaggttg aaggtaatgt gggcaatcag aatggtctta aagcccaggg aaattccgaa
     2641 ggcaatgaag gtcagcatca gggagatgcc ggtcacaatc tcggaattta aaatagggat
     2701 gttgttgatt cccatcacaa tgtttttcgg cgtccgcttc atgctgctga ttccgatagc
     2761 cgccagggtg ccgagaatgg tggcggccag agcggagata aaggcgatca ggagagtgtt
     2821 gtagagagcc tccataatgg ccgggctttc aaacatctgc gtataccatt tggtggtaaa
     2881 gccgccccac agagtcctgg atttggagtc gttaaaggac aggatcatca tggtgacaat
     2941 gggcgcatag agaaaaatca ggatgattac caggtaaaaa tcctggaaaa atttccggag
     3001 ccggccgcgc cgggagcttc tgcctgagaa gctgccagcc atatctgccg tgttgttgtt
     3061 cgtgttcatc agaatgcagt tccctccccg tttttatcgt atttggcgat gagcgccatg
     3121 ctgatcagga tgaagaccat caggaccaga gaaaggccgg atcccaggtg ccagttgctt
     3181 cccttggtaa attcctgctc aattacattt ccaatcagca gaattttgct gccgccaagg
     3241 aggttggaga tgacgaaggt agtcagggca ggcacgaaaa ccatggtgac gccgctgaca
     3301 atgccgggaa ggcttaaggg cagccacaca tggataaagg tctggaattc gttggccccc
     3361 agatccttgg cagcgttaat ggtattgtcg tcaattttta caagcacgtt gtaaaccgga
     3421 agcaccataa aaggcaggaa gttatacacc atgcccagga caatggccgc cggagtgttg
     3481 ataattgaga ttccaggcag tcccagtgtg gataagatgc cgttgatcac tccatttttc
     3541 tcgaggagcg tctgccaggc cagagtccgc aggagaaaat tcatccacat gggaaggata
     3601 aagataaata caataaagct tccttttcca atgtgctttt tcctgagaat catggccagc
     3661 ggataggcca gaagcaggca gattacggtg cttaacagcg agagccccag agataaaaac
     3721 agggccttgg agtgctcctg tgtagcgatg gcggcgatat tttccagggt gaaggcgccg
     3781 cctgcgtccg tcaggccgta ccaggcgatt aaaagcaggg gaataatggt aaagccggtc
     3841 atccagatca ggtacggccc cgccaggtat tgtttcatgt tttttttaga aacgctattc
     3901 atcaattcct accgcctcct cgtcctcaga agcaggctta ttcatgatct gaatgtcgaa
     3961 aggatccaca tgaatgccta ccttttctcc taccggaaac aggtccgtgc tgtgaaccag
     4021 ccactcccag ccgtctggcg tagtgacctc catctcgtag tggacaccct tgaaaatcag
     4081 atgggtcaca acgccctgca gggttccctc ctccggtttt accagatcga tgtcttccgg
     4141 gcggataact acgtccaccg gagttttgca gccaaagccc ttgtcaacgc aggcaaattt
     4201 ggctcctgca atctccacca gaccgtcgtg aagcatgatt ccgtctaaaa tattgctttc
     4261 tccaatgaaa tcggccacaa aggcgttttc cggctcattg taaatctgtt ctggagatcc
     4321 catctgctgg atgtagccct ggttcatcac cacaatcgtg tcggacatgg tcagggcctc
     4381 ctcctggtcg tgggtgacat aaataaaggt aatgcccagc tcgtttttca gccggatcag
     4441 ctcgtactgc atatcctggc ggagcttcaa atccagagcg cccagaggtt cgtccaggag
     4501 aagcaccttg ggctcgttga caatggctct ggcgatggcg attcgctgct gctggcctcc
     4561 gcttaaggag tccacggatc ggttctcaaa gccgtccagg tttacaagct tcagggcgta
     4621 gcggatcttg tcgtcaatgt agcttttggg ctttttcttg attttcagcc cgaaggcgat
     4681 attttccgca atgctcatgt gagggaacag ggcgtacttc tgaaaaacgg tgttcagctg
     4741 ccgtttgttg gggggcaggc tggtaatgtc ctttccgctg aacagtacct ttccccgatc
     4801 cggcgactcg aagccgccga taatgcgcag ggtggtggtt tttccgcagc cgctggggcc
     4861 cagcagggtg acaaattcat tttctttcac tgacaggcag agatcgtcca gaacgatgct
     4921 gccgtcgaaa cttttcgtga tatttacgag atcaatgaat ggctgactca ttttaaaatc
     4981 ctccgtattc ttccgcgtcc gcgcatgatg acgccggttt ttcctaaaaa ctggggggag
     5041 agctgatcca cagaagggaa gctccgtcct ctgtctctat gtagtgtgtc tgagcgcttg
     5101 taaaataaaa ggattctcct ttttttgcct tataaatact ggttccgata tggatcagaa
     5161 tgctgccgct taaaagataa cccaattctt ctccctcgtg aggcgtgtcg gggcaggtgg
     5221 aaccgcccgg ctccagggtg agaagaatcg gctccatgca gtttttctga gcgttgggga
     5281 cgatccactg gatggtattt ttcagctccg cgtctgtttt ggtaaagaaa tcctgctttc
     5341 cgaatacgat ctgttcgtcg gcagtctccg caaaaaattc cccgatggtc gttccgagac
     5401 actggagaat atccatcagc gtggcgatgg acggggaggt taaatcccgc tccagctggg
     5461 aaatgaagcc tttggacagc tccgcccggt cggccagctc ctcctgggtg agtcccttca
     5521 atatcctgag cgcttttaac tttgatccga tgctcatgcc gtctttctcc tttcgccgct
     5581 tggcggcgcc tttgcttcgc gcttgtgact aaatataaaa ataatcttaa agtttagaaa
     5641 taataaacat gcgacatctg ttattatacc ccctctgcgc ggagtgtcaa caggaaaaca
     5701 gcggcggaaa actgcgtctt tcaggttcac aaaccataaa aactgtgata ttatgttttt
     5761 accttcagtt tacaagagca catacggtca ggacagagag gagtgtgtgt tcttgtaaac
     5821 tgagggtatc ttaaatagca acaatacaga aggcctcctt gctgatgaga agggacctgg
     5881 tgctgcgctt gaggaggata atgcatgatg gcaggcaagt acatggctta tgtgggatca
     5941 tattcctata atggacaggc aaaaggaatt acggtttacg acgtggatgt ggagaacggg
     6001 tattttaaat acaggtgcga ggtagaggtg gacaattcct cctatctggc tgtttcccac
     6061 gacgggaaga cgctctactc catcgcggac gagggcgtgg tgtccttccg cattctcccg
     6121 aacggagggc tgacgcggtt aaacagcgcc ggaattaagg gcatgagagg ctgccatctg
     6181 gccacagacg cggaggataa gtacattttc gtatccggat accacgacgg caaggagacg
     6241 attctgagac tgaacccgga cggcacagta ggggaaatta cagataaagt attccacaag
     6301 ggactgggca gcgtggcgga gcggaatttc cgtcctcatg tcagctgcgc cggacggacg
     6361 ccggacggcg aatttttaat ggctgcggat ctgggcatcg atcaggtgaa aatttacggc
     6421 tttgacagcg agaagggaac catttcccag gtagacgcag tgcgctgcga gctggagtct
     6481 gcgccgagac agtttgtgtt cagcaaagac ggacggtttt tctatctgat gtatcagctg
     6541 aaaaacgcca ttgacgtgta cagctatgag tatgagccgg gggagagagt gccgaagatt
     6601 gagaggctgc agaccgtttc ctctacggac acgccggcgg gcgagctgac ggcggcctgc
     6661 gctatccgca tgtctccgga tgacagatat ctgttctgca gcaatgcggg agacaactgc
     6721 gtgagcattt acgagcggga tccggataca ggacttctga ccatgaagtg ctgccttcct
     6781 atcagcgggg attacccgaa ggatatcgcc atattcccgg atcagaagca catggccagc
     6841 atcaaccatg ccagcggcac aatttcattt ttcagcattg actatgagaa cggcctgtta
     6901 atgatgaacc accgttccat tgacgtaaat gagcctaact gctgcgtaat cacgaagatt
     6961 ccggagtaga agaaagtcag gagggacagc gaagcgatgg cgggatcgac atttggaaca
     7021 attcttagaa tgacaacctg gggggaatcc cacggcccgg ccctgggagt gacggtagac
     7081 gggtgtccgg caggccttga gctctgcgag gcggatgttc aggaatatct ggacagaaga
     7141 aagccggggc agggaaaata ttccaccaag agaaacgagg gcgatcaggt ggagatcctg
     7201 tctggagtgt ttgaggggaa aacgacagga accccgattt ccatgatggt gagaaaccgg
     7261 gatcagcgtt ccagggatta cggcgagata gcgtcctgct accggccggg acacgcagac
     7321 tatacttttg atcagaaata tggctttagg gattacagag gcggaggccg ttcctccggt
     7381 cgggagacca ttggacgcac agccgccgga gcggtggcgg caaagctgtt aaaggagctt
     7441 ggaattacag tgacggcata tgtcagccag atcggcccgg tgcggatcgc gccggagcgg
     7501 tttgaccttc aggcagcccg cgaaaacagg ctctgcatgc cggattccca ggcctcagag
     7561 gaagcggagc agtttttgga cgggaagatg gcggagcggg attcagccgg cggtgtggta
     7621 gagtgcagaa tcaacggtat gcctgcaggc ataggagagc ctgtgtttga caagctgagc
     7681 gctaacctgg ccagggcgat ctgctcgatt ggggcagtga agggctttga gatcggggac
     7741 ggatttgccg ccgcctcttc ggtgggaagc gaaaacaacg acgcctttgg ccttgatcag
     7801 tcaggccata ttgtcaagca gaccaaccat tccggaggta tcctgggcgg tatcagcgac
     7861 ggaagcgaga tcatattccg ggcagcgttt aagccgacgc cctctattgc ggctccccag
     7921 cgcacggtaa actccagagg cgaggagaca gagctggaga ttaagggccg ccacgatccg
     7981 attattgtgc ccagagccgt ggtggtggtg gaggctatgg cagcctttac ggcagccgat
     8041 atgatgcttt taaatatggg cgccagagtc gataaaatca gggaattcta tcagaagcag
     8101 cgctgactgc caggaacagg aggcgcggcg ggaagaagag aagaatgtcc cggcgcgtca
     8161 gcgcgcagaa gctgacgcca gcataggaac atgacagaga agatgccgca tccgtttgga
     8221 tatgccgcat cttcttttgg cagagagaga aaatgaagct gaaatataaa gccaaaatat
     8281 aaagccagaa acagacgtta agacaggagg aaatcagaat ggaagagaga agaacggata
     8341 tcatcgggcc aggcgtagcg gatgaagcgg cagacaaagc cgaggtggag agaatcagag
     8401 ggcaggtaag gcagctgtta ggagagtttt ttgaggcggc gggcatgaaa agaggccaga
     8461 ttctcgtggt cggatgctcc tccagcgaga tcgagtccca ccgaatcggc tcctattcca
     8521 gccgtgaaat cgggcaggct gtatttgagg aaatttacca ggaaacccag aagaggggaa
     8581 tttacctggc cgcccagtgc tgcgaacact taaacagggc tctcattgtg gaggaggagt
     8641 gcgccgagaa gtacggtctg gaacaggtaa acgtagtgcc gcagctgaag gcgggaggtt
     8701 ccttcgccac agcggcgttc tctgcctttg aaaatcctgc ggcagtggag cggattcagg
     8761 ctcacggcgg cattgacatc ggagatacgt ttatcggaat gcatctgcgc ccggtagcag
     8821 tgccggtccg cacctctgtg agggagattg gaagcgccca tgtgacctgc gccagaacca
     8881 ggttaaaatg tatcggcgga gagcgcgcgg cgtacaggta aaagaaagat ttaaagcgcc
     8941 tggaaacagg ctgtctttgc cagcggaaag aggcggcggc aggaagcggt aaagacagag
     9001 aggaaaggac agagaggaaa ggaccagaaa acattggaga tgaaaaaaaa cgacagattt
     9061 gtgcttaaaa tagaagatat gggagaaaac ggagagggaa tcggacggct ggacggctac
     9121 atctggtttg tgaaggacgc ggtgatcggc gatgtgatcg aggccggagt gacgaagatg
     9181 aagaagcagt acggttttgc ccgtttaatc cgcgtgatcg agccgtctga gtacagaaca
     9241 gaggaacgct gtccttcggc ccgccgctgc ggcggctgcc agattcaggc agtggattat
     9301 caggaacagc tgaggctgaa ggagaaaaag gtatacaaca atctgaaacg gatcggaggg
     9361 ctttccagtc tgctgcttcc gggcggggaa gaaacgacag agcagacgaa ggaagagaca
     9421 gagcgaaacg ctgtcgttat ggaaccgatt atcggcatgg agaatccctg gcgttacagg
     9481 aataaggccc agttcccatt tggaaggaat aaggatggaa ggattgtcac aggcttttac
     9541 gcagggagga cccacgatat agtggagcag gaggactgcc ttctgggcgt ggaggagaac
     9601 cgggaaattt tatcaataat tcgaaatttc atggaagaat ataaaataga gccttacaac
     9661 gaggagactc acaggggttt ggtccgccac gtgctgatcc gcaagggctt tcagacaggg
     9721 gaactcatgg tatgcctggt gataaacggc aggaagctgc cagggcagca ggcgctcaca
     9781 gaacgcctgc tggaaattcc cggcatgacc agcatttccc tgaacgtgaa ccaggagaag
     9841 accaacgtga ttctgggaaa ggaattgata aatctctggg gagaaggcca tattacggat
     9901 tacattgggg cggttcagta cagaatttct cctctgtcct tttaccaggt gaatccggtg
     9961 cagacagagc gcctttacgg tacggctctg gagtatgccg gtttgacggg aaacgagacg
    10021 gtgtgggatc tctactgcgg aatcggaacc atttccctgt ttctggccca gaaggcgaag
    10081 caggtgtatg gagtggagat cgtgccccag gcaatcgacg acgccaggga gaacgccaga
    10141 ctgaaccaca tggaaaatgt ggaattcttt gtggggaagg cggaggaggt gctgccggaa
    10201 cagtacgaga gaaaccagat ctatgcggac gtgattgtgg tggacccgcc cagaaaggga
    10261 tgcgatgaaa agtgcctgga gaccatcgta aaaatgtccc cgaagcgggt ggtgtacgtc
    10321 agctgcaatt cctccaccct ggcgcgggac gtgaagtacc tggaggagcg gggctaccgg
    10381 acagagcggg tgaggtgcgt ggatatgttt ccgcatagcg ggcatgtgga gacggttgtg
    10441 aaactgaaga aatggtgata aatgattttg aattttgtct tgatacaata aaattgctag
    10501 agatgcagca tcagagtgca ctctaacaca cccaccagga ggagctttca acatgaactc
    10561 aattaccatc cgtgaagcgc tggcagagga cgccagtcag ctgatagaat atatgaagac
    10621 agtaggcgca gagacggaaa atctctcctt cggcggggag ggacttcctg tttctatcga
    10681 gcaggaggcg gcgtttctgg aggcggttcg ccaggagaag acgtccgtcc atctggcagc
    10741 gtttaaggac ggggaaatca taggagacgg aagtcttacg gggctgcccc gaagaatgag
    10801 ccaccgggcg gagctggggc tcagcgtaaa gaaggcatac tggaatcagg gggtaggaag
    10861 cgccctgatg cgcagactca tacagtatgc agaggaaaac ggcatcgagc ttctgagcct
    10921 ggaggtgaga agcgacaata tccgtgccgt ccgcctgtat gagagctttg gctttcagcg
    10981 tatcggcacg tctccggcgt attttaagat agacggcaga tatgcagatt ttgagctgat
    11041 gtacctggat ctgaggaagg gcggccaaat ataaaacagc taaaaacaga atgatcataa
    11101 atggaaaaga aggctttcgg catctaagcg ggaggtcttc ttttttctta tttttcagta
    11161 tttacccctt cttaacgccg ctttctgaat ccttacccca tcttaaaagc atttgtgcta
    11221 cccttgtaga cgtaaggagg aagcggttat gagagcgatt ttaaaatctt ttcacaggat
    11281 agaggaaacc tttgacagga aggcggaggc ctttgcgctg cgccatccgt ttctggcttt
    11341 ttgggtgatg tttgtgggaa tgccggtgat gcttcttttg acggtttcac tgagcacgat
    11401 ggtgcttgtg atgcccttcc actatctttg gggatggtgc tagacggatc ttaatggaac
    11461 ttttatgcgc ggctgcacct gttaatcccg ttttaatcgg cgcagtgcta gaataggtag
    11521 gcgaaggagg aaacggacta tgatggattt gattatgctt ggaatacttg ccgggtgctt
    11581 tggtctggtg aagctgttcg cagatttctg cgagagacag gtggaactga aggatcggaa
    11641 acagtaaaac aggagggata aattatggcg gtattaggac ttatgatagc ggctctggga
    11701 gcgtatctgg tgtatgcgct ggtaaatccg gagaagctgt agagaaaaga cagcagaaag
    11761 aaaaggcaga aagaaaaggc aggaggaaaa gcaggaggaa aaaagctatg ttacagattg
    11821 tgcttacact ggcgatcttt gtgatattgg tgatcccgac gggaagatat atgtaccaca
    11881 ttgcatcgaa tcagaaaacc tttgcagacc cggtgttcga cccggttgac aaggttatat
    11941 acagagtctg cgggattcag ggcggggaca tgggatggaa aaaatacacg ctgtccctgc
    12001 tgatggccaa cggggtgatg gtgtttaccg gctatctgat tctcaggctt cagggacttt
    12061 tattttttaa tcccaatgga atcggaagca tggaggagag cctgagcttc aacacgatta
    12121 tcagttttat gaccaacacg aacctgcagc actattcggg agagagcggt ctttcctacg
    12181 cagggcagat gtgcgtcatt atttttatga tgtttacttc agcggccagc ggctacgcgg
    12241 cctgcatggc cttctgccgg gggctggcag gacgcccgct tggcaatttt tacagggata
    12301 tggtgagaat taccaccaga atcctgattc cggcggcatt tttaacggga cttctcttag
    12361 tcggccaggg tacgccccag acgctggcag gcaatctgac ggtagaaacc atagaaggaa
    12421 aatttcagga tattgccgtg ggcccggtag cggccctgga atccatcaag catctgggaa
    12481 ccaacggcgg cggcttcttc ggcgccaatt cgtccacacc gtttgagaat ccgacggtta
    12541 tttccaatat ggtggagatg atttccatga tgcttctgcc gggatcctgc gtcgtcacct
    12601 ttggactgat gctccacgac agaaaggacg ggaaaaaacc tctgtttgga aggcagggag
    12661 ccgtgatttt cggcgcgatg gccattattt tcctgattgg cctggctgtc tgcttcagcg
    12721 cggagagagc gggaaatccg gtggttagcg ccatgggact cagccaggat atgggcagca
    12781 tggagggaaa ggaaacacgt ttcggcatgg aacagtcggc ccttttcacc acagtgacta
    12841 cctcgtttac cacaggaacc gtcaacaaca tgcacgactc tctgacgccg ttaggcggcc
    12901 tggtgccgct gctccacatg atgttaaact gtgtgttcgg cggcaagggc gtaggcctga
    12961 tgaacatggt aatgtatgtg attctggcag tctttatctg cggactcatg gttggaagaa
    13021 cgccggagta tctgaataag aagatagagg gaaaggaaat gaagctggtg gccattgtca
    13081 ttctgattca tcccctgtta attctcggct tttctgctct ggcggtgtct gtgcagggcg
    13141 gactttcagg aattacaaat ccaggctttc acggcctgac gcaggtgctt tacgagtacg
    13201 cctcctccgc cgccaacaac ggttccggct ttgagggact ggcggacaac agcctgttct
    13261 ggaacgtcac cacgggactt gccatgtttt ttggccgcta cctggccatt gccgcccagc
    13321 tggcggttgc aggttccatg ctggccaaga gaaaggtcaa tgagtctgtg ggaacactgc
    13381 gcacagacaa tacaaccttc atgattgtgc ttgtattcat cgtttatata tttgctgctt
    13441 taacattctt cccggctctg gccctgggcc ctgtggcaga gcatctgtcc ctgtggatgt
    13501 agcgcgggga agcgggaaaa gcagaaagga gacttacaat ggctaagaaa caaggcgcga
    13561 aatttgttac gccggatatt ttaaaatctt ctgtcatcgg cgcgtttaag aagctggatc
    13621 ccagatatat ggtgaagaac cccgtcatgt ttgtggtgga agccggatgc tttgtcacgc
    13681 ttcttctcac cttttgtccc actctgttcg gcggccaggc ggagtaccag atttataatg
    13741 gaattgtgac agccgtatta tttgtgacca tactgtttgc aaattttgca gagtcggtgg
    13801 ctgagggccg gggaaaggct caggcggaat ccttaaagaa gacgaagcag gacacgaagg
    13861 cccgccttct tctcccgggc ggaggcgaga agatgataaa cgcctctgat ttaaaaaagg
    13921 gagacattgt gttagtgaag ctgggcgaag tcatccccaa cgacggcgag gtgatcgagg
    13981 gaattgcctc tgtggacgaa tcggccatca caggcgagtc cgctcctgtc accagagaag
    14041 ccggaggaga tttctcctcc gttaccggcg gcactacggt ggtgtccgac tggctgaaaa
    14101 taaggattgc ggcggagccg ggacattcct tcctggataa aatgatttct ctggtggagg
    14161 gagcttccag acagaaaacg cccaatgaaa ttgcattaaa tactctgtta attgtgttaa
    14221 ctctgatatt tttaattgtt gtggtaactc tgtatccgtt tgccgcctac ctgggagtgg
    14281 agattcctgt ttcctgggcc attgccctga tggtctgcct gattcccacc accatcggag
    14341 gacttctctc tgccatcggc attgcaggca tggaccgggt gacgagattt aacgtcatcg
    14401 ccatgtcggg aaaggcagtg gaggcctgcg gagacgtgga caccatgatt ttagacaaga
    14461 cgggaacgat tacatatgga aaccgcctgg cggcggagtt ttatccggta aacggcgtgg
    14521 aaaaagagga tttgattgac tacagcgtca tgagctctct catggacggc acaccggagg
    14581 gcaaatctac ggtggacctg ggacgccgga tgggctgcgt tctgacagag gaggcggccg
    14641 gccagatgaa ttttattgag tttacagccc agacgaaaat gagcggtgtg gatttacagg
    14701 atggaaccgt tgtgaggaag ggcgcttccg aggcagtgaa gcggtttgtg gaggaaaagg
    14761 gaggaagcat cccggcagat ctggaggaga ttgtaacaaa ggtctccaat ctgggaggaa
    14821 cgcctcttac cgtctgcgta aacgacaaaa tcttaggcgt aatctattta aaggatacgg
    14881 ttaaacctgg actttccgag cgttttgccc gccttcgtga aatcggaatc aagacgatta
    14941 tgtgtacggg agacaatcct ctcacagcgg caaccattgc cagggaggca ggcgtggacg
    15001 gctttatcgc agagtgccgc cctgaggata agattgaggc cattaagaaa gaacaggcag
    15061 agggaaagct ggtagccatg acaggcgacg gaaccaacga cgctccggcc ctggcccagg
    15121 cggacgtagg cctggccatg aattccggaa ctcaggcagc caaggaggcg gccaacatgg
    15181 tggatctgga ttctgacccc accaagattc tggaggtggt ggaaatagga aagcagcttt
    15241 tgattaccag aggctccctg accaccttca gcgtggccaa cgacattgcc aaatatttcg
    15301 ccattattcc ggccatgttt accatggtgc tgccgcagat gcagatttta aatatcatgc
    15361 gcctggccac tccggccagc gcgattttgt cggctttgat ttttaacgca ctgattattc
    15421 cggggctgat tcccatcgcc atgcggggcg taaaatataa gcccatgaag gcggaaaagc
    15481 ttctgcttag gaatatggga atctatggat tgggcggtat gattgtcccc tttgtgggaa
    15541 tcaagctcat tgacctggtg acagccccca tgctgtctgc aattggaatg taggaggaag
    15601 agacaatgaa aggttttctt aaaatgttca ggactgcgtt tgtcttctgt attgtgatga
    15661 tgcttttgtg ttccttcgcc tacccgctgg ctctcacggg agccagccag gcggtgatga
    15721 aggagaaggc gggcggaagc ctgattgaca gggagggaaa tctcacagac gatccagaga
    15781 aagcggtggg ttccgtcctg ttaggccagg attttacaga ggattatttc ttccatggaa
    15841 gagtttcctc tgttcactat aatacataca cagaggagca gaaagagagc ggagagtacg
    15901 gcggcgtttc ctcaggttcc tttaactacg gaaactccag cccggatctg gaggccagga
    15961 taaaaaagga tttagacagc tttttggcct ctcatccagg agtaaaggct gaggacgttc
    16021 cggcggatct cttgacggcg tcaggatctg gcctggatcc tcacatcagc ccggaggcag
    16081 ccagagtaca gattccggcg gtggcagaac actcaggact cagcgaggag gagatttccc
    16141 ggattgtgga ggagaacaca gagggaaagg ctctcggcgt attcggtgaa gagagagtca
    16201 atgtattaaa atgtaattta gccattgcaa gagccatggg actgatttag cgcggcataa
    16261 cgcggcgcaa ggcagtttct atgcctggaa tgaaagagga gggaggaggc gggaaggcca
    16321 tgcaggagga gagacctgat tcagaacagc tcttaaagcg tttgaaatac gaggaacggg
    16381 agcagaaaaa gagaacaaga gggcgtctta aaattttcct gggctacgcg gcgggctcgg
    16441 gaaaaaccta cgccatgctg gaagctgccc acgaggcgaa ggcccacggg atcgacgtgg
    16501 cagccgggta catagagccg cacgaccggc cggacaccca ggccctgact aaggggctgg
    16561 aaatgctgcc gcctgcgttt atggagtata agggcatgaa gctcagggaa tttgacctgg
    16621 acggggcatt aaagcggaag ccgcagctgc ttctggtgga cgagctggcc cacaccaact
    16681 gcaggggctg cagaaacgaa aagcggtacc aggatgtgaa ggagcttctg cgggccggaa
    16741 tcagcgtcta cacaactctg aatatccagc atttggagag tcttaatgac ctggtgggaa
    16801 gcattaccca tatcgacgtg cgggagcgga ttccagacac ggtatttgat cacgcggatc
    16861 aggtagaagt ggttgatatt gaaccggaag atctgatcga gcggatgaag gaggggaaaa
    16921 tctaccggaa ggagcaggcg gaccgggcgc ttcagaattt tttccgaaga gagaggctgg
    16981 cggctctcag ggagattgcc ctgagaagat gcgcggatcg cgtcaaccgg attgccgagg
    17041 aggagagaag cctgctggag cgccaggact atcacacagg agagcatatc ctggtctgca
    17101 tcacggcggc accctccagc gccaaagtaa tacggacggc ttcccgtctg gcggacgcct
    17161 ttcacggaac tttgacagga ctctgtgtgg agacgccgga tactcaggag gcgggggaaa
    17221 agacgaagga agccctcaga aacaacatgg agctggcgaa gcttctgggg gcgaagattg
    17281 tgacggtgtt cggatctgat gtggcggctc agattgccca gtatgcgatt gtcagcaacg
    17341 tgtcgaaaat tgtgctgggc agaaccaacc attttaccat gcggcccatg taccgatcgg
    17401 agcttctgga gaagctgacc tacatggcgc ctaatattga catatatatt attccggata
    17461 tgaggcagac gaagcgctgg catcccagac aaagcgccgc aaaaaggcag gaaagctgga
    17521 aaaaatgtgc ggctggcctg gcggcggcta cggcggttat gctggcggct acggcgctgg
    17581 ccctgatact ccggatgttt gtgttctcag aagccaatac cattatgatt tatatgatgg
    17641 gagttctgct tgcctcctgc gcagccagcc ggaagctgtg cgctctgtat tcagccctgt
    17701 taagcgttat tttatttaat tttttcttta cagagcctct atacagcctg aaagcctatg
    17761 atcaggcgta tcccatcacc tttctcatgc tgtttctggc cggattattt acggccactg
    17821 tcaccggaaa gctgaaacga cagaacgtgg agagcagcaa gacagcttac cgcacaggaa
    17881 tcctcctgga aaacagccag aagctcagac ggtgcaaaac gagagaagac gtgtggagac
    17941 aggcggctgt gcaggcggga aagctgctga atctgtccat tctgttctat cctgtcagga
    18001 aagacggagc ggtggaagag cctcttctgt tccccagaaa aggtatggat ccggaagagc
    18061 tgaaacgatg cgtaaacgcc caggaaaagg gcgtggccca gtggacagcg tcaaaccgcc
    18121 gccgggcggg ggcctgcact catacgctgc cagacgccat ggccatgtat ctgcccgttc
    18181 aggatgaaga gcagattcac gccgtcatgg ggatttttct ggaggagaga aggcctgtcg
    18241 ccgaatttga gtacagcctt ctcaccgcca tgcttaacga gacaggagtg aagctgaaag
    18301 atttctttat acaatcttaa tacttttctt tacaaactca taccgattta atacatttaa
    18361 agatataata aagagcgtaa taaacctgcg gtaaacgtaa ggcacagatc tggataatat
    18421 ctggaaggag tacataagat tatgaaatct attttgctga ttgggctggg gagatttgga
    18481 cgccatatag cgagaaaatt gagcgaactc cgccatgagg tcatggcggt ggacatagac
    18541 gaaaagcggg tggaggcgat gcttccctat gtgacaaacg cccagatagg agacgctacg
    18601 gacgaggatt ttatccgctc cctcggcgtg agaaattacg acgtctgcat ggtggccatt
    18661 ggagacaatt ttcagagctc tctggagacc acgtccctgt taaaggagat gggagctgcc
    18721 cttgtggtgt cgagagcgtc cagagacaga cagaaaaagt ttcttttgaa gaacggagcg
    18781 gatgtagtga tttatccgga gcgccagctg ggagagtgga ccgccatgcg ctacagctcg
    18841 gatcatattt tcgactatgt ggagctggac ggagagcacg cgatttttga ggtgtctatt
    18901 cccagagagt ggttcggcaa gaccattggg cagattgatg tgagaaataa gtacaatatt
    18961 aatattatgg ccttaaagca caatggagtg atgcagttaa atatcacctc cgatacgctt
    19021 ctttcttttg agtacacaat gctggtgctg ggaaggatta aagatgtgca aaagtgcttc
    19081 catatttgat aaaattgtgg ataagacaga ctatcagggt gaagtaagga gctgacagag
    19141 atggcaaagg aacggggacg tctgaaaatc tttttcgggt acgccgcagg cgtgggaaag
    19201 acctacgcga tgcttcaggc agccctggcg gccagggaaa agggaatcga tgtggtgatt
    19261 ggttccgttt ctcctcatac aatgccggaa acggcagcgc tggcagacac tctggagcag
    19321 ctgggcggcg acggccgaag agcggtagga gaatttgacc tggatgcggc gattttgcgc
    19381 agtccgcagc tgattctggt ggacgagctg gcccgggcga atccggaggg gtgccgccat
    19441 gccagacggt atcaggacgt ggaggagctt ctgaaagcgg gaattgacgt ctacacgaca
    19501 gtaaatgccc agaacattga aagcctcagc gatattgcgg ccacaattat gaagcacagt
    19561 atcaaagaca ggattccgga cgatgtgttt gaccgggcag atcaggtgga attgatagat
    19621 attgagcctc aggagctgat ggaacgcctg aaatgcggca cgattgatga aaaacagggg
    19681 aaaaatcctc cggcggaggc ctatttttcc attgagaatc ttacggctct gcgggagatt
    19741 gccctgcgcc ggtgcgcgga tcggattaac cgttccgggg acaggagggg aacggaccgg
    19801 ggggaggact tgtttgcaga ggaacacatt ttagtctgcc tttccgccgc cccctccaat
    19861 gccagaattg tgcggacagc cgcgcggatg gcccaggtgt ttcacggaag ctttacggcc
    19921 ctgtttgtaa agacgccgga gtttacccgc tgggacgagg agagcttaca gcggcttcag
    19981 gagaacatcc gcctggcaga gcagctggga gctgatatcc aggtgattta cagcaacgat
    20041 attccctttc agatcgcaga atttgcccgc ctgtccaggg tgacgaagat tgtgatggga
    20101 aggagcgcgg cggccagatc tcactttttc ggaaggccgg ccttgacgga aaagctgatt
    20161 ttgaacgcgc cgaacttgga tgtgtacatt attccagatg ccgtctccga gaaggccagg
    20221 tacagggcga agaagagcgg aagaagca
//
LOCUS       DBMDUW010000045        19834 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1669_length_19834_cov_4.576294, whole genome shotgun sequence.
ACCESSION   DBMDUW010000045 DBMDUW010000000
VERSION     DBMDUW010000045.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 19834)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 19834)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19834
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1669_length_19834_cov_4.576294"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            118..1365
                     /locus_tag="ACZPCR_08925"
     CDS             118..1365
                     /locus_tag="ACZPCR_08925"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0015501 - glutamate:sodium symporter
                     activity [Evidence IEA];
                     GO_process: GO:0015813 - L-glutamate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter family protein"
                     /protein_id="HIR1231034.1"
                     /translation="MILGPQCANVLPVPSTWFDTYSLLPGILIVPVVAAVPLGLKFGG
                     GKSDGINPDFLKNVFPLIGIGLAAAMFQFAVGYGTHVLFSGENLYDVFGIELSIGFVG
                     GHGTAGTLGNMLSALNLPYWETSQGVATTTATFGIVGGILIGIMMINWAARHGQTAML
                     KKPADIPEPLRVGFEKDIKKQNSVGRETTLSSSIDTLAFHAALIFVACGLAYLLLMGA
                     EKFQIPVLKSISVWAYGMIVMFAIWGIMCKLKLDYLVDDKIKSKVSSSFTEFAVIAAI
                     ASLPIKAVAAYIVPILVMVAIGYVITTGVLFILCKRLLKGFWFEQMIGTYGMSTGVFL
                     TGVLLLRICDPDLESPALANYSLSYTITSIIYFAMLNLFIVLPMSSGAGVTTLAATGL
                     GLAAVLFAIVSSRISFGSQFKGN"
     gene            1474..2922
                     /locus_tag="ACZPCR_08930"
     CDS             1474..2922
                     /locus_tag="ACZPCR_08930"
                     /inference="COORDINATES: protein motif:HMM:TIGR01891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004180 - carboxypeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HIR1231035.1"
                     /translation="MQNYEELFEKLNAKIWDYAELKFEEYQSSEALIDMMKAHGFSVE
                     RGLAGMDTAFRATAGKGRPVIGLLAEYDALSGLSQKAGQLEPIPRKETENGHGCGHCL
                     LGTAAAGAALMAKDYLIQTGREGTVVLIGCPAEEGGSGKAYLARAGVFDDLDAALTWH
                     PAGGNAVLTGSLQANCQAYFRFHGVSSHAAGSPHLGRSALDAVELMDVGVNYMREHME
                     PTDRIHYAITDTGGSSPNVVQNHAEVLYLIRSTDNNKVKRLYERVKNIARGAALMTET
                     NVEAVFDKACSNILSNSILEQLLYDCMKTIPLPSYTEEELAYAEQMKKTITDADIASD
                     MSLMMVHGAEKRRLASLYRELPMANFVVEHQHQDLFLPGSSDVGDCSHATPTAQFVGA
                     CFVPGTPAHSWQMTAQGKEKTAVKGMFYAAQVLSEACRRLFEKPEIVKQAREVFENDT
                     EGKPYECPIPTEILPNANGKRKKHSYASGQEG"
     gene            2953..4152
                     /locus_tag="ACZPCR_08935"
     CDS             2953..4152
                     /locus_tag="ACZPCR_08935"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015544584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20 metallopeptidase family protein"
                     /protein_id="HIR1231036.1"
                     /translation="MTIAESAKSIEEHLRQLRREFHRHPEISGNEKKTAARIVRELSE
                     IGGFEIREGVGGHGVIAELSGALPGPVIALRADMDALQIEEETGLSFCSENCGVMHAC
                     GHDNHITMVLGAARLLAQRKDELKGKVRLIFQPSEELSPQGGSRKMIEAGALKGVDAV
                     FGIHVWPDLPLGKVGIKAGPLMAASDHFTVTIKGKPSHAARPDEGIDALVAGAQFVMA
                     AQTIVSRNADPMKSVVITIGRLNAGTRYNIIAGECVLEGTCRTFDPAVRDLAERRLDE
                     ILSGVCTASGCTGELHYERGYMAVVNDTKMADYVRESADKILGNGTAVSVEPAMTSED
                     FSFYLDEKPGVFAWIGTTPPGDIVWPLHSSHYSPDEGVLWRGSALLAGLALGLWEKQQ
                     VMLLEKS"
     gene            complement(4138..5442)
                     /locus_tag="ACZPCR_08940"
     CDS             complement(4138..5442)
                     /locus_tag="ACZPCR_08940"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HIR1231037.1"
                     /translation="MITVSIISPKVSLQAINRVIEQNDFGCIFHKYVYHTLEEIQDIY
                     YKCKDHCDIIFCSGEFGYYQLMNIPNIEKPCAFVSYETKHFLAIALDFVQTHPDIPLN
                     RIYCDFLIPSNNYLDLHRYLRPELMPHCCTDPVLSYETLFHTARELWNEKKIDIAFVR
                     STNSLKRYEDENIPYLYIFPDDNTIADSIRSAVSTAKLLLSSVVHKASILIRLVCPDN
                     LLGTELEYQNITFLKALVDFRKEYGASFSVQTFITYFQITWELEDSSHLPALLRSLIL
                     YLDTHSEIPFRLGAGLATSLSNSLEQAEQALNESVHYGKNDGFLINEQLRLMGPLSVQ
                     DPLHVSYDNEKIMKFSKDNGINEGNLQKIIGLFLKNPRQVLTSSLLAEWLNITPRSCN
                     RIIQKLCLTGLLTQIHTEGSMEKGRPVKTYCFNETACFSTFF"
     gene            complement(6146..7396)
                     /locus_tag="ACZPCR_08945"
     CDS             complement(6146..7396)
                     /locus_tag="ACZPCR_08945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016283373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family RNA-guided transposase"
                     /protein_id="HIR1231038.1"
                     /translation="MKVVYQTCCGIDVHKSFLVATIIKTTSGVDPSYQKKRFSTFNNS
                     ILQLKNWLIENQCRDVCMESTGKYWGPVFNLLEDEMNVTIANPKWVKAVKGNKDDTKD
                     SKWIGDLFRLGLVQGSYIPCKPIRILREFTRYRYKLTSCRTSEKNRYQNALTVCNVAL
                     DSVVSDIFGKSATSVIDYLIERSDNSINHEEIASRLLRSLKKKSDSVIESIEGYQMTA
                     PQKYRMRLVRAHLDYITSTINDIDTMLDSLIAPYENAVQLLCTIPGVDRNSAITVISE
                     IGTDMTPFSNSKRLCCWAGLTPGSNESAGKKKSVRITRAGVYLKPALVQVAHAAVKSD
                     KSPYYKQKYERIMKRRGKKRAIIAIDRMILTAIYQMLSTGEAWNPTDLYKTDMPEPLK
                     EKQKEKAIKQAKKLLIREGILSES"
     gene            7693..10140
                     /locus_tag="ACZPCR_08950"
     CDS             7693..10140
                     /locus_tag="ACZPCR_08950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002576602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0045910 - negative regulation of DNA
                     recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HIR1231039.1"
                     /translation="MNQKALKTLEYYKIIDTLTEYASTEPGKRLCRELLPSCDYQEIL
                     QNQQETSDAVTRVRQKGSISFGGVKDITDSLKRLEIGSSLNITELLAVSSVLTVSARA
                     KSYGRREESELPDDSLDEMFRLLEPLTPVNTEIKRCILSEDEISDDASPGLRQVRRQM
                     KIINDRIHTQLNSVLNSSRTYLQDAVITMRDGRYCLPVKAEHKSQVPGMVHDQSATGS
                     TVFIEPMAVIRLNNEMRELEIQEKREIEFVLMALSSQLVPYTDTLTENLAILAKLDFI
                     FAKAALSRHYNCTEPKFNNKRYINIKDGRHPLLDPKKVVPINIHLGDSFDLLIVTGPN
                     TGGKTVSLKTVGLFTLMGQAGLHIPAFDGSELAVFDNVFADIGDEQSIEQSLSTFSAH
                     MTNIVSILGQADSRSLCLFDELGAGTDPTEGAALAVAVLSFLHHMECRTMATTHYSEL
                     KVFALTEPGVENACCEFSVETLRPTYRLLIGIPGKSNAFAISKKLGLPDYIIEDAKRH
                     IEKEDAAFEDLLANLEESRVTIEKEREELNAYKAEIADLKKRLEQKEERFQDQKERLL
                     EKARTEAQQILQDAKDTADSTIRNINKLASQSGVGKELEEQRSRLRNKIKDVDKKLAS
                     KKPQTPQKTISPKSLKIGDGVKVISMNLKGTVSSLPNARGDLYVQMGILRSLVNIKDL
                     ALLNESSISGPGLDNSAGSAGGRGAGRNSAKTPGAFGKGKSSQSGIKMSKSFSVSPEI
                     NLIGLTVDEAVPELDKYLDDAYLAHLPQVRVVHGRGTGALRAGVHKHLKRLNYVKEFH
                     LGEFGEGDTGVTIVTFK"
     gene            10239..10952
                     /locus_tag="ACZPCR_08955"
     CDS             10239..10952
                     /locus_tag="ACZPCR_08955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013271092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HIR1231040.1"
                     /translation="MAEKQKILIVDDDENIAELISLYLTKECYETKIVGDGEEALAVF
                     PVFKPNLVLLDLMLPGIDGYQVCRELRTSSQVPIIMLSAKGEIFDKVLGLELGADDYM
                     IKPFDSKELVARVKAVLRRYQAAPQTPEPAGSDQKGQYVEFPDLIVNLTNYSVIYNGH
                     SIEMPPKELELLYFLASSPNQVFTREQLLDHIWGYEYIGDTRTVDVHIKRLREKIKDH
                     EKWALTTVWGIGYKFEVKR"
     gene            10957..12360
                     /locus_tag="ACZPCR_08960"
     CDS             10957..12360
                     /locus_tag="ACZPCR_08960"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002595163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HIR1231041.1"
                     /translation="MIHSLYYKFILGYLLFGLLGFAAIATLSSDMTYDYLVEHRAEAL
                     YDEANLIAENCSDIYQGKRLDPDMVKPQIDAMASYLQSSIWVVNHDGQVTVDSQNRLT
                     GKTIDSFDPTAGGSKPYSIGTYYGQFSSDVLSVSAPITGNFNTYGYIVIHLPMKLITE
                     EQNSILNIMYTTAAILFGLSLIILLFFTKTVYVPLKKITYAATEYAAGNLSYSISLHT
                     QDEMGYLANTLNYMAMELNKMEEYQHKFIANVSHDFRSPLTSIKGYLEAIIDGTIPPE
                     LYEKYLNIVIAETERLNKLTQGMLTLNSLDSKGFLTRTNFDINRVIKDTAAAFEGACS
                     ARGITFDLTFNDSIQMVYADLGKIQQVLYNLIDNAIKFSYENSVIYLQASEKHEKIFV
                     SVKDTGAGIPKDSIKKIWERFYKSDPSRGKDKKGTGLGLAIVKEIIQAHDENIDVVST
                     EGVGTEFIFSLPKASSF"
     gene            complement(12728..14023)
                     /locus_tag="ACZPCR_08965"
     CDS             complement(12728..14023)
                     /locus_tag="ACZPCR_08965"
                     /inference="COORDINATES: protein motif:HMM:NF012544.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HIR1231042.1"
                     /translation="MAIGVGSIIGSGIMSLTGIGIERTGRSIFIAFMIGGFIALLSRS
                     PQIFLNSVARYRGGDYSMVGTFLGPRWTGTYSMISLLTSVTLAMYALSFADYAMPFLP
                     WLTRKAIALSVLTILFVTNVFGVNAFAKIQGAAVILLVIALTVFTGVGLANLDPNYFD
                     PATFMPNGLSGLWSAAVLMSYTCDGAQYVTQMSAEAKNPTRDIPRVMLFSTLGIAAFY
                     GLMGVVAAGVLPVDQVAGQPLNVVAEAVLSKPLYYLFMIGGAWMALLTTLNSSIASCT
                     KPLMQACNDGWYPSSLARLHPKFRTPIILLEIYYVIGFVPIMFNFDIGIISDITITVG
                     SITKAMIILSLLRMPKVLPGAWKQSNFHVKDSMLMAIGVLDLIVVVISGVTSSLELPV
                     KLLAANLAVVVFAFVFGSVRFRSGKVKVEKSYELPEEEA"
     gene            complement(14112..15335)
                     /locus_tag="ACZPCR_08970"
     CDS             complement(14112..15335)
                     /locus_tag="ACZPCR_08970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004180 - carboxypeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HIR1231043.1"
                     /translation="MSPEETRMIEAIDRSREKLHKIARRIWEFKEVGWEEFNSSLLLM
                     NELEREGFEVERGLTGRHPKFDQEIDMPTAFKAVFRGKEDGPVVGVLLEYDALPNGHA
                     CGHNLISSAGFAAALGLKEAFQEKGTVIVYGTPAEELEGSKHYILEGGYMDEVDLMLA
                     SHYGSDWGSEVTGKAIVWPTHDNWVTFKGRASHASSSPEKGRSALDAVILTTMGLEFL
                     REHMPETNRIHYIISKGGTAANSVPDLATLNVELRTNDSAELNSLMKRVDNVIKGTAL
                     MTDTTPVYRWDAPWYCATPVPTLYRRAALYAADLGIDSSRFTFGNLPKASSDLGCVAY
                     KIPAVEITFPIVPDGEPAPVGHADETACITGNEYPIDQSILAGKLMALTGLRIGGNKE
                     ELELIQSEFASHFKE"
     gene            complement(15569..16390)
                     /locus_tag="ACZPCR_08975"
     CDS             complement(15569..16390)
                     /locus_tag="ACZPCR_08975"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231044.1"
                     /translation="MPGEIPGFFYLKDCPEFEDWVEEKRNQQTARILRELKVQLEEPS
                     AVRNPERIRLLIDTWKHWSPWDEEMVLTGMRLYGQAEKYDWGVKLYQEYARRLKEDLD
                     EEPSHQAEVLFQTLLHRKEVSSLRSQTSKEAFFGRLAEIQAVDEQIFLFLSNEDARSV
                     IIEGEVGVGKTALMRQIFGMDHRGEALEIYANCYGAESDVPLRAFRDCFQCLERLQGE
                     RRISLSGKEERLIRRMTSGELRTALYHYERSSERQQAEAVCARLEAEALKRKEKA"
     gene            complement(16357..16710)
                     /locus_tag="ACZPCR_08980"
     CDS             complement(16357..16710)
                     /locus_tag="ACZPCR_08980"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="HIR1231045.1"
                     /translation="MEYEVTLLGIPGVCRDREPVRFPYRKAEGIFYYLCVEKHTNRDE
                     LVSLFWGSGDEASGRKNLRQALFQLRKLLGEEVIVLQGRNDLKLNQRVEIKTDWDMPE
                     RDFSLCQERFLDFFI"
     gene            complement(16846..18666)
                     /locus_tag="ACZPCR_08985"
     CDS             complement(16846..18666)
                     /locus_tag="ACZPCR_08985"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: protein motif:HMM:NF014567.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1231046.1"
                     /translation="MGSWTGILLAFLITAFIAAGVMAFYPWLSSEMAEGKRVFTAKEW
                     EQLTGSSGSEAEYDYETESYDSVVISDYDYYENNGGYVSYGAHVSHRGDEVWVLPGYG
                     RVQAALGLITLCAAALVTVSAAVFAAVKPLKMTESVLFKAPFEIMLFAGFMILGASIG
                     SGMGPGMACASLSGETMAVLTTEYYHLDAETAQVIMMALNYGAWLFMGLALFWMMETA
                     MSFFTVGPVRWFKERTLTGKLGRALKKAASRTCRELEQINFNEKSTRSILKIVGINFI
                     LLTVLCSLWFYGIFGLLVYSAVLYVILQKAYGRVREKYQNLLKVTNELAEGNLDVEIT
                     EDLGVFEPFRREIGKIQSGFKKAVDAEVKSQRMKTELITNVSHDLKTPLTAIITYVNL
                     LKEPGITNQEREEYVQVLERKSLRLKALIEDLFEVSKANSQTMKLNLMEVDVVSLMKQ
                     VKLELSEQLSDSGVDFRFQLPEKRVALTLDSEKTYRIFENLLVNIAKYGMPGTRAYVE
                     IEETEMPEADEGGAASEAGENRENRGEVRISMKNISASELPKDAGELTGRFVRGDQSR
                     NTEGSGLGLAIVKSFVELQKGSFQVETEADLFKAVIVWKK"
     gene            complement(18680..19423)
                     /locus_tag="ACZPCR_08990"
     CDS             complement(18680..19423)
                     /locus_tag="ACZPCR_08990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIR1231047.1"
                     /translation="MEIQTGADAGTILIVEDDKEIRQGIEIFLKGQGYRVFQAADGIE
                     GLKIIEEQDISLAIVDVMMPRMDGITMVIKLREKYDFPVIFLSAKSEEVDKIMGLNMG
                     ADDYVTKPFTPMELLARVGSQLRRYQRFLRLLEERQSGTARAQEERVYRIGGLELHED
                     TVEVFVDGAPVKATPMEFKILLLLMKHPGRVFSADEIYERVWNERAVNTDTVMVHVRN
                     IREKIEINPRNPKYLKVVWGVGYKIEKQQ"
BASE COUNT         5126 a         5135 c         4633 g         4940 t
ORIGIN      
        1 acaagttgtg ccttgctgca taaaaagcgg ccagcaacat ttagctgctg gccgggaaaa
       61 ttttatattt tttctctgtc ctcttgacgg ggagcagttc atgggggatt cctgcttttg
      121 attttagggc cccagtgtgc gaatgtcctt cctgttccat cgacctggtt cgatacatat
      181 tctctgcttc ccggaattct gatcgttccg gttgtagcag ccgttccgct gggattgaaa
      241 tttggaggtg gaaaatctga tggtataaat ccagactttc taaaaaacgt atttcctctt
      301 atcggaattg gactagcggc agctatgttc cagtttgccg tcgggtacgg aacccatgtg
      361 ctgttttcag gagaaaatct ctatgacgta tttggaatcg agctgtcaat cggttttgtt
      421 ggcggacatg gtacagccgg tactctggga aatatgctct cagcgctgaa tcttccctac
      481 tgggagacct ctcagggtgt ggcaaccaca acggctacct ttggaatcgt aggaggcatc
      541 ctgattggaa ttatgatgat taactgggca gcccgacacg gacagacggc aatgttaaag
      601 aaaccggctg atattccgga acctctgcgg gttggatttg aaaaagatat caaaaaacaa
      661 aattccgtag gccgtgaaac taccctgtct tcctctatcg acactctcgc cttccacgcc
      721 gctctgattt ttgttgcctg cggcctggca taccttcttt taatgggagc tgaaaaattt
      781 cagattcccg ttctgaagag tatttctgtc tgggcctacg gtatgatcgt gatgttcgcc
      841 atctggggaa tcatgtgcaa acttaagctg gactatctgg tagatgacaa aattaaaagc
      901 aaggtttcca gttccttcac agagtttgcc gtaattgcag caattgcaag tctcccgatt
      961 aaagcagtag cggcatatat tgtcccgatt cttgtgatgg tggcaatcgg ttatgtaata
     1021 acgactggtg ttctctttat tctctgcaag cggctcttaa agggcttctg gtttgagcag
     1081 atgatcggaa cttatggcat gagcactggc gtattcttaa caggcgttct gcttcttaga
     1141 atctgtgatc cagatctgga aagccccgct ttggccaatt attctctatc ctacactatc
     1201 actagcatta tttattttgc tatgctgaat ctttttattg tccttcctat gagctctgga
     1261 gcaggcgtga ccactttggc agccacagga ctaggtcttg cagccgtact atttgcaata
     1321 gtgagcagcc gtatttcttt cggaagccaa tttaagggaa attaaaataa ctgagacgat
     1381 cagaaaacac ttcgataatt tcaaatctga caagaaagtt tcgtcctttc tggacgaagc
     1441 ttcctgcaaa ggcaggtaag tgaggtaaaa gaaatgcaga attatgagga acttttcgaa
     1501 aaactaaatg ccaaaatatg ggattacgcg gaactgaaat ttgaagaata tcagtcgtct
     1561 gaagccctca tcgacatgat gaaagcacat ggattctcgg tagaaagagg gctggccgga
     1621 atggatacgg cattcagagc cacagctgga aaagggcgtc ctgtaatagg gcttttggca
     1681 gaatacgacg ctctgtccgg cctcagccag aaggcaggac agctggaacc aattcccaga
     1741 aaagaaacag aaaacggcca tggctgcggt cactgtcttc tgggaacagc tgcagccgga
     1801 gctgctctga tggcaaaaga ttatctgatt caaaccggca gagaaggtac tgttgtgctg
     1861 attggatgcc cggcggaaga aggaggttca ggaaaagctt accttgccag ggctggcgtg
     1921 tttgatgatc tggacgcagc gctcacctgg catccagctg gaggaaacgc tgttttgaca
     1981 ggttctctgc aggcaaactg ccaggcctat tttcgttttc acggcgtttc ctcccacgcg
     2041 gcaggatctc ctcatctagg ccgaagcgcc ctggatgccg tagagctgat ggatgtaggc
     2101 gtaaactaca tgagagaaca catggagccc actgaccgga ttcactatgc tattactgat
     2161 acaggcggca gttctcccaa tgtggtacag aatcatgcgg aggttcttta tttgatccgt
     2221 tccaccgata acaataaagt gaaacgattg tatgaaaggg taaaaaatat tgccagaggc
     2281 gctgctctga tgacagaaac aaatgtagaa gcagtatttg acaaagcctg ttccaatatt
     2341 ctttccaaca gcatcctgga acagcttctt tatgactgca tgaaaacgat tcctcttcca
     2401 tcctacacgg aagaggaact ggcctatgca gaacaaatga agaaaacgat cactgacgct
     2461 gatatagcca gtgatatgtc cctgatgatg gttcatggag cagaaaagag aagactggct
     2521 tccctctacc gcgagcttcc tatggccaat tttgtagtgg aacatcagca ccaggatctg
     2581 ttccttccgg gctcttccga tgtgggagac tgcagccatg caacacccac agcccagttt
     2641 gtgggagcat gctttgtgcc tggaacgcca gcccactcct ggcagatgac agctcaggga
     2701 aaggaaaaga ctgcagtaaa gggaatgttc tatgcagccc aggtactttc tgaagcttgc
     2761 cgtcgtctgt ttgaaaaacc agaaattgta aaacaggccc gagaagtatt tgagaacgat
     2821 accgagggaa aaccatacga gtgccccatc ccaacagaaa tcctgcctaa cgcaaacgga
     2881 aaaaggaaaa agcactcata tgccagcgga caagaaggat aaaaaataga caaaaacagg
     2941 aggtgatgaa aaatgacaat tgctgaatcg gcaaagtcca tagaggaaca tttaagacag
     3001 cttcgaagag agtttcacag acatccagaa atatcaggaa atgagaaaaa gacagctgcc
     3061 agaattgtga gagagctttc cgaaatcggc ggatttgaga tccgcgaagg cgtaggagga
     3121 catggggtaa tcgccgaact ttcaggagct ctgccgggcc ctgtaatagc tctcagggca
     3181 gatatggatg cgctgcagat tgaggaagaa acaggtcttt ctttctgctc agaaaactgc
     3241 ggagtcatgc atgcctgtgg gcacgataat catattacca tggttctggg ggcagcccgt
     3301 cttctggctc aaagaaaaga tgagcttaaa ggaaaggtgc ggctgatttt tcagccatca
     3361 gaagaactgt ctccgcaggg cggatctaga aaaatgattg aagcaggtgc cctgaaagga
     3421 gttgacgctg tatttggaat acatgtctgg ccagatcttc cactcgggaa agtgggaata
     3481 aaggctggcc cgctgatggc tgcctctgat cacttcacag tcaccattaa gggaaagccc
     3541 agccatgccg caagacctga cgaaggaatc gatgctctgg tggcaggagc ccagtttgtg
     3601 atggcagccc agactatcgt cagcagaaat gcagatccca tgaagtccgt cgttataacc
     3661 atcggaagac tgaatgctgg aacccgttat aatattatag cgggagagtg tgtgctggaa
     3721 ggaacctgcc gtacgttcga tccagctgtc cgggatctgg cagaacgcag actggatgag
     3781 atattgtccg gagtctgtac cgcttcaggc tgtacaggag aactccacta tgaaagaggc
     3841 tatatggcag tggtaaacga cacgaaaatg gcagactatg tcagggagtc agccgacaaa
     3901 attctgggaa acggcacagc tgtatctgta gaaccggcca tgacctctga ggatttttcc
     3961 ttttatctgg acgaaaagcc aggggttttt gcctggattg gcacaacgcc gccaggggat
     4021 atcgtatggc cgctgcatag cagccactat agccccgatg aaggagttct ttggagggga
     4081 tccgccctgc ttgcaggact tgcactggga ctgtgggaaa aacagcaggt tatgttatta
     4141 gaaaaaagtt gaaaaacagg cagtctcgtt aaaacagtat gttttaacgg ggcggccttt
     4201 ttccatagag ccctctgtgt gtatctgcgt caaaagacca gttaggcaga gcttctggat
     4261 aatgcggttg cagcttctcg gagtgatgtt gagccactct gccaggagag aagaggtaag
     4321 cacctgcctg ggatttttca ggaaaaggcc gataatcttc tgtagattgc cctcgttgat
     4381 cccgttatct ttggaaaatt tcataatttt ttcattgtca tacgaaacat ggagaggatc
     4441 ctgaacggac agaggtccca tcaggcgaag ctgttcattg atcagaaagc cgtcattttt
     4501 tccatagtgg actgactcgt tcaaggcttg ctctgcctgc tccagactat tggaaagaga
     4561 ggtggcaagg cctgcgccca aacgaaaagg gatttcactg tgggtgtcca aatacaggat
     4621 cagggagcgc aaaagcgcag gaagatggct gctgtcctca agctcccagg taatttgaaa
     4681 ataagtgata aaagtctgaa cagaaaagct ggctccatat tcctttctaa aatctaccag
     4741 agcctttaaa aacgtaatat tctgatattc cagctccgta cccaaaagat tatcaggaca
     4801 gacaagccgg atgagaatac tcgctttatg tactacagaa ctaaggagaa gctttgccgt
     4861 agatactgca cttcgaatag aatcggcaat cgtattatca tctgggaaaa tataaagata
     4921 tgggatattc tcgtcctcat accgtttcag gctattcgtt gagcgcacaa aagcaatgtc
     4981 tattttcttc tcattccaca attccctagc tgtgtggaat aatgtttcat agctaagaac
     5041 tggatctgtg cagcagtggg gcatcaactc agggcggagg taacggtgca gatccaaata
     5101 attattgctg ggtatcaaaa agtcacagta aatccgattg agcgggatat ccgggtgagt
     5161 ctggacaaag tccaaggcaa ttgccagaaa atgttttgtc tcataggata caaaagcgca
     5221 gggcttttcg atattaggga tattcataag ctgatagtag ccaaactcac cgctgcagaa
     5281 gataatatcg cagtgatcct tacatttata atagatatcc tggatttcct ccagagtgtg
     5341 ataaacatat ttatgaaaaa tacagccgaa atcattctgc tcaatgacac ggttaatggc
     5401 ctgaagagat acctttgggc tgataatgct gacagtaatc atatgtgact ctccgtttcc
     5461 aatagttgtc agtggaacat aagaactgat atttcgtaca aaaacatccg tccttctcca
     5521 ttccctgtat aataatttac tatagccgct ccgggaaagt caatatattc ctgagaggca
     5581 tgaacagcaa atatatgaat ggcagctttt ttgataaagc ctggcaaagc ttgtagattt
     5641 tgtctaaaca gcctgacctt cttattaata ttccctgtcg aatcatttcg catttattat
     5701 agaagcattc cattcagcat taacggcctt cttaaaaaac tatgctggca tctctagtat
     5761 ttgtgtggta aaatggctga aattatacta actgcaaaac agccggtatt ttcggcagcc
     5821 gccaaataga cataactgtt cacttgtctc attgctttat gatataatat atcccatcag
     5881 caggaaaaca agcggctgcg aagcaggcat ttgttttcac ctgatgggat aacgagtaaa
     5941 ctgtctgcgc agcagacaat aagcacgaag tgcccgttta cgagtctttt taatcagcag
     6001 gaaaacaagc ggctgccccc attaattttt tataaggtga ctactgtgaa agaaagtaga
     6061 ggacagccaa caaatggcgt actttaaata agctgtctta tggcagcctt tgaaaaatta
     6121 ttattttgag gagctaagaa gctaattacg attcggaaag aatcccttct ctgatgagca
     6181 gtttcttggc ttgtttgata gccttttcct tctgtttttc tttcaaaggt tcaggcatat
     6241 cagttttata taaatcggtc ggattccacg cttcaccagt agacaacatc tgatagatag
     6301 cagtgagaat catccgatcg atagcaataa tggctcgttt tttaccgcgg cgcttcataa
     6361 tacgttcata tttctgctta tagtaaggag acttatcgga tttcacggct gcatgagcga
     6421 cttgcaccaa tgcaggtttg aggtagacac cggcacgtgt tatcctgaca gatttcttct
     6481 taccagcaga ttcattgctg ccgggagtca gtcctgccca acaacagagg cgcttggaat
     6541 tagaaaacgg agtcatatcg gtaccaatct cggagataac cgtaattgca ctgttgcggt
     6601 caacacccgg aatggtacac agtaactgga cagcattttc ataaggggca atcaaagaat
     6661 caagcatagt gtctatatca ttgatggtag atgtgatata atccagatgt gcgcggacga
     6721 gacgcatacg gtatttttgg ggagcagtca tctgataccc ttcgatggat tcaatgacac
     6781 tgtcagactt tttctttagg gaacggagaa gtctggaagc tatttcttcg tggttgatgg
     6841 aattgtcgga tcgttcgatc aggtagtcaa taacagatgt agctgatttc ccaaagatat
     6901 cggaaacaac cgaatctaat gcgacattac agacagtaag cgcattctga tatctattct
     6961 tttcgctggt acgacaagaa gtcagcttgt aacgatatct tgtaaattca cgcaggatac
     7021 ggatcggttt acaagggata tagctgcctt gaaccagacc taatcgaaac aaatccccaa
     7081 tccacttgga atctttcgta tcatccttat tgcctttgac tgcttttacc catttgggat
     7141 tggcaatggt gacgttcatt tcgtcctcta aaaggttgaa tacaggaccc cagtatttac
     7201 cggtagattc catacagaca tcacggcatt gattttcaat tagccaattt ttaagttgca
     7261 ggatagaatt gttgaaggtg gagaaacgtt tcttttggta agaagggtct actccggaag
     7321 tggttttaat gatagtggca acaagaaaag atttgtgaac atcgatgcca cagcaagttt
     7381 gataaacaac tttcatggtc aacactcctt tcaaagtgag ataaagaagc cattgactgt
     7441 tccaccacac atttaacaga gaagttaaaa caattcttac tgtacggtct aaaagagcca
     7501 cgtatttgtg cttgaaagat ggaactcaca ctgattatta tgctgtctaa aacagaagaa
     7561 agtctttacg actcacctca ccgtgctttg tagtataact tctttaacaa ttattttatc
     7621 agtaacgtgg gggattaaaa agactttcat tcctatttgt gccgccgact tggcggcgga
     7681 atggagatta ttatgaatca aaaagcatta aaaacattgg aatactataa aatcattgac
     7741 actctgacgg aatatgcctc cacggagccg ggaaaacggc tctgccggga gcttctgccc
     7801 tcctgcgact atcaggaaat tctgcagaac cagcaggaga cctccgacgc ggtgacgcgg
     7861 gtgcgccaga agggcagcat ttccttcgga ggcgtaaagg acattactga ctccttaaag
     7921 cgtctggaga ttggaagctc tttaaatatt acggaacttc tggccgtcag ttccgtgctc
     7981 accgtgtccg ccagggcgaa atcctacggc cgcagggagg aatctgaact tccggacgac
     8041 tccttagacg aaatgttccg tctgctggag ccgctgactc ccgtcaatac ggaaattaag
     8101 cggtgcattc tctcggaaga cgagatcagc gacgacgcca gccctgggct cagacaggtc
     8161 cgccgccaga tgaaaatcat taacgaccgc atccacaccc agctgaactc tgttttaaac
     8221 tccagccgca cctatctcca agacgcggtc attaccatgc gggacggccg ctactgtctg
     8281 cctgtcaagg cagagcacaa gagccaggtt cccggtatgg tccacgacca gtctgccacc
     8341 ggctccaccg tatttatcga gcctatggcg gtcatccgtc tgaacaatga aatgcgggag
     8401 ctggaaatcc aggagaagcg ggaaattgaa tttgtgctca tggctttaag ctcccagctg
     8461 gttccataca cggacacgct gactgaaaat ctggccattc ttgcaaagct ggatttcatc
     8521 tttgccaagg cggctctgtc ccgccactac aactgtacgg agccgaaatt taacaataaa
     8581 cgctacatta atatcaagga cggccgccac ccgctgctgg atccgaagaa ggtagttccc
     8641 atcaacatcc acctgggaga cagctttgat cttctcattg tcacaggccc caacacaggc
     8701 ggcaagacgg tatccttaaa aactgtgggc ctgtttactc tcatgggaca ggcgggcctc
     8761 cacattccgg cctttgacgg ctctgaactg gctgtctttg acaatgtatt tgccgacatt
     8821 ggagacgagc agagcattga gcagagtctc agtaccttct ctgcccacat gacgaacatt
     8881 gtgtccattc tggggcaggc agattcccgc tccctgtgcc tgtttgacga gctgggagcc
     8941 ggaacagatc cgacggaggg agccgctctg gcagtggctg ttctgtcctt cctccaccac
     9001 atggagtgcc gcaccatggc caccacccac tacagcgagc tgaaggtatt tgccctgaca
     9061 gagcctggcg tggagaacgc ctgctgcgag ttcagcgtgg agacgctgcg ccccacctac
     9121 cggcttctca tcggaatccc cggtaagagc aacgcctttg ccatttccaa aaaattggga
     9181 cttcccgact acattatcga ggacgccaaa cgccacatcg agaaggagga cgcggccttt
     9241 gaggacctgc tggccaatct ggaggaaagc cgggtgacca ttgagaagga gcgggaggag
     9301 ttaaacgcct acaaggcgga gatcgcggat ctgaaaaagc ggctggagca gaaggaggag
     9361 cggttccagg atcagaagga acgcctttta gaaaaggcca gaaccgaggc ccagcagatt
     9421 ctccaggacg ccaaggacac cgccgattct acgatccgga atatcaacaa gctggccagc
     9481 cagtccggtg tgggaaagga gctggaggag cagagaagcc gcctgagaaa caagatcaag
     9541 gacgtggaca aaaagctggc ctccaaaaag cctcagaccc cgcagaagac catttccccc
     9601 aagtccctga aaatcggcga cggcgtaaag gtcatttcca tgaatttaaa gggaactgtc
     9661 agctccctgc ctaacgccag gggcgatctg tacgtgcaga tgggcattct ccggtctctg
     9721 gttaacataa aggatctggc cctcttaaac gagtcctcta tctccggccc aggcctggat
     9781 aacagcgcgg gaagcgcagg cggccgcggc gcaggaagaa acagcgccaa gacgccgggg
     9841 gctttcggca agggcaaatc ctctcagagc ggaatcaaga tgtccaagtc cttctctgta
     9901 tctcctgaga tcaatctcat cggtctgaca gtggacgagg cggttccgga gctggacaaa
     9961 tatctggacg acgcctatct ggcccacctg ccccaggtcc gcgtagtcca cgggcgcggc
    10021 acaggcgctc tcagggccgg cgtgcacaag cacctgaaac gcttaaacta cgtgaaggaa
    10081 ttccatttag gcgaattcgg cgaaggagat accggcgtta ctatcgttac atttaaataa
    10141 ataagtcaat gcgcgcagac agacgcgcag cgcagggaac tgtactgcct tcgcagcagg
    10201 gcgcagtccc gcgtcagggg gaaaggagta gcagcgtcat ggctgaaaaa cagaaaatac
    10261 tgattgtgga cgacgatgaa aacattgcag agcttatctc tctgtatctg acaaaagaat
    10321 gctacgaaac gaaaatcgtg ggggacgggg aagaggctct ggccgttttc cctgtcttta
    10381 aaccgaatct ggtgctcttg gatctgatgc ttcctggcat cgacggctac caagtctgcc
    10441 gggagctcag gacttcctcc caggttccga ttatcatgct ctccgccaag ggagagattt
    10501 tcgacaaggt gctggggctg gagctgggag ctgacgatta catgattaag ccctttgact
    10561 ccaaggagct ggtggccaga gtcaaggcgg tgctccgccg ctaccaggcc gctccccaga
    10621 cgccggaacc ggctggttcc gaccaaaagg gacagtatgt ggaatttccg gatttaattg
    10681 tgaacctgac caattactct gtcatctaca acggccattc cattgagatg ccgcccaagg
    10741 agctggagct gttgtatttt ctggcctcct ctcccaacca ggtatttacc agggagcagc
    10801 tgctggacca tatctgggga tatgagtaca ttggagacac cagaacggtg gacgttcaca
    10861 ttaaacgtct ccgcgaaaaa atcaaggatc atgaaaagtg ggctctgact accgtctggg
    10921 gcatcggcta caagtttgag gtgaagaggt aacgccatga tccactctct ctactacaaa
    10981 ttcattctgg gctatctcct gttcgggctt ctgggcttcg ccgccatcgc cactctctcc
    11041 tccgatatga cctacgatta tctggtggag catagggcgg aagccctcta tgacgaggcc
    11101 aatctgattg ctgaaaactg cagcgatatt taccagggaa aacggctgga tcccgacatg
    11161 gtaaagccgc agattgacgc catggcttcc tacctccagt cttctatctg ggttgtcaac
    11221 cacgacggcc aggtgacggt agacagccag aaccgcctga ccggaaaaac catcgacagc
    11281 ttcgatccca cggcaggagg cagcaaaccc tattccatcg gaacctatta cgggcagttt
    11341 tcctctgacg tgctgtccgt ctcagccccc attacgggaa atttcaatac ctatggctac
    11401 attgtgatcc accttcccat gaagctgatc acagaggagc agaacagcat tttaaatatt
    11461 atgtatacca cagcggccat cctgttcggg ctgtccctga ttatcctgct gttttttacg
    11521 aaaaccgtgt acgttccgct gaaaaagatc acttacgcgg ccacggagta cgcggcaggc
    11581 aacctgtcct acagcatcag ccttcacacc caggacgaga tgggatatct ggccaacact
    11641 ctgaactaca tggctatgga gctcaacaaa atggaggaat accagcacaa atttattgcc
    11701 aacgtgtccc atgacttccg ctctcccctc acctccatca agggatatct ggaagccatt
    11761 atcgacggca cgatcccgcc ggagctctat gaaaaatact tgaatatcgt cattgccgag
    11821 acggagcggc tcaacaagct gactcaggga atgctgacct taaactcctt agacagcaag
    11881 ggcttcctca ccaggacgaa ctttgacatc aaccgggtga tcaaggatac ggcggcggcc
    11941 ttcgaggggg cctgcagcgc cagaggcatt acctttgacc tgacgttcaa cgattccatc
    12001 cagatggtgt acgcggatct tgggaaaatt cagcaggttc tctacaacct gattgacaat
    12061 gccatcaaat tcagctacga aaactctgtg atctacctgc aggcgtcaga aaagcatgag
    12121 aaaatttttg tctctgtgaa ggataccgga gcaggcatcc caaaagacag cattaaaaaa
    12181 atctgggaac ggttctataa aagcgatccc tcccgcggga aggataagaa gggaaccggc
    12241 ctaggacttg ccattgtgaa agaaatcatc caggcccacg atgaaaatat cgacgtggta
    12301 agcacagaag gcgtgggaac cgagtttatt ttcagccttc cgaaagccag cagcttttag
    12361 agaaggaggg aaaagggctg aaaacgaaga agggaaagtt ttacgcgctc cactgtaagt
    12421 cgctgtaaaa ctttccctct tctgtctgtc aacatttttc tcgaaaaagg aaatctttag
    12481 tgtcagtgta cactgacgcc atgaaccgtt ttgagctttc ctgatatcat ctgctgctca
    12541 gcccgactcg ttccgccaga tatcctctcc ccgcagggag aaaagaaatt ttccagtgac
    12601 tttaattgga acagggaaaa tttcttttct tcttccatag cctcttctgc atatcgcgcg
    12661 gggaaaattt ttcggtgact ttaattggaa caagaaaaat tttccccgcg cgtatatcct
    12721 gcctatctta cgcctcttcc tccggaagct cgtagctctt ttccaccttc acttttccgc
    12781 ttctgaaacg gacgcttcca aatacaaagg caaatactac gacagccaga ttcgccgcca
    12841 gcagcttaac cggaagctct aaggaggagg taactcctga aattacaact acaatcagat
    12901 ccagcactcc gattgccatc agcatgctgt ccttcacatg gaaattggac tgcttccacg
    12961 cgcccggcag caccttgggc atccgaagca ggcttaaaat gatcatggct tttgtgatag
    13021 agcctacggt aattgtaata tcgctgataa tgccgatatc gaagttaaac ataatcggca
    13081 caaatccaat cacatagtaa atttccagca gaataatggg tgttctgaac ttgggatgaa
    13141 gtcttgccag agaggacgga taccagccgt cgttgcaggc ctgcattaat ggtttcgtac
    13201 aggaagcgat ggagctgttc agcgtggtga gcagggccat ccatgcgcct ccgatcatga
    13261 acaggtagta taacggcttg gaaagcacgg cctcagctac cacgtttaaa ggctggccgg
    13321 caacctggtc tacgggaagc acgcccgctg ccactacgcc catcaggccg taaaaggctg
    13381 cgattcccag cgtggaaaac agcataaccc gtggaatatc cctggtagga ttctttgcct
    13441 ccgcgctcat ctgagtcacg tactgggcgc cgtcgcaggt atagctcata agcaccgccg
    13501 cgctccacag tccggaaagt ccgttgggca taaaagtagc aggatcaaaa taattcggat
    13561 ctaggttggc gagacctaca cctgtaaata ccgtcagcgc gattaccagc aggattaccg
    13621 ccgctccctg aatcttggca aaagcgttga cgccaaacac gttggttaca aagagaatcg
    13681 tcagcacgct gagagcaatg gcctttcttg tcagccacgg cagaaacggc atggcgtagt
    13741 cggcaaatga cagggcgtac atagccagcg tcacgctggt gagaagggaa atcatagaat
    13801 aggttcctgt ccacctgggg cctaaaaagg ttcccaccat agagtagtcg ccgcctctgt
    13861 acctggccac agaattcagg aaaatctgcg gcgatcggga cagcagtgca ataaatcctc
    13921 ctatcataaa cgcaataaaa atggaacgtc ctgttctctc aattccgatt cctgtcagag
    13981 acataattcc agagccgata atggatccga ctccgattgc catcagatcc cagaacacgc
    14041 ttcagatcct ttgtggatgt taactgcttt gacatagtct gactctcctt tccccctgtt
    14101 cagggcctcc cctactcttt aaaatggctg gcaaattctg actgaatcag ctccagttcc
    14161 tccttatttc ccccaatccg aagtcccgtc agggccatca gctttccggc cagaatactc
    14221 tggtcaatcg gatactcgtt tcccgtgata caggccgtct cgtcggcatg gcctaccggt
    14281 gcaggctctc cgtccggcac aatggggaag gtaatctcca ccgctggaat tttgtaggcc
    14341 acacagccca gatccgagga agctttgggc aggtttccga aggtgaagcg ggagctgtcg
    14401 attcccagat ccgcggcata cagggccgct ctgcggtaca gggtgggaac cggcgtcgcg
    14461 cagtaccagg gagcgtccca gcggtacaca ggcgtcgtgt ctgtcatcag cgccgtgccc
    14521 tttatcacat tgtccacccg cttcataagg gaattcagct ctgccgaatc gttggtgcgc
    14581 agctccacat tcagggtagc caggtcggga accgagttgg ccgctgtgcc tccctttgaa
    14641 ataatgtagt gaatccggtt ggtttccggc atgtgctctc ttaaaaattc cagtcccatg
    14701 gtggttaaaa tcactgcgtc cagggcgctt ctgccctttt ccggcgagga ggaggcatgg
    14761 gaggccctcc ccttaaaagt cacccagttg tcgtgggtcg gccacacaat ggccttgcct
    14821 gtcacctcag agccccagtc cgatccatag tggctggcca gcattaaatc cacctcgtcc
    14881 atgtagccgc cctctaaaat atagtgtttc gatccttcca gctcctctgc aggggtgcca
    14941 tagacaatca cggttccctt ttcctggaac gcctccttaa gccccagagc cgccgcaaag
    15001 ccggcggagg aaatcaggtt gtggccgcag gcgtggccgt ttggaagagc gtcatactcc
    15061 agcaggacgc ccactacagg tccgtcctct tttccgcgaa acactgcctt aaaggctgtc
    15121 ggcatatcga tctcctggtc aaatttcgga tgccttcccg tcagccctct ctctacctca
    15181 aatccttccc gttccagctc gttcatcaga agcagagagg aattgaactc ttcccagcct
    15241 acctccttaa attcccagat ccgtctggct attttgtgaa gcttctctct gcttctgtca
    15301 atggcttcaa tcattcttgt ttcctctggg ctcattctgt ctcctccttt tatctcttat
    15361 catttttagc gccgttctct ttctcttctg ttttctatca tacggatccg ccattaaaaa
    15421 accgtcaact ctccctttaa tttcaagaaa aataaaacat tttccgtata tagacaaaaa
    15481 atcagactga tactcttcta aaattaagaa tttttcagtc tgatttctcc gtgattgata
    15541 gtatttttct atatctttct atgccttttt aagccttttc tttccttttt aacgcttctg
    15601 cctccaggcg cgcgcagact gcctccgcct gctgccgttc ggagcttctt tcgtagtggt
    15661 aaagcgccgt tcgcagctct cccgaagtca ttctgcggat cagccgctcc tcctttcctg
    15721 acagggaaat cctgcgttcc ccttgcagac gctccagaca ttgaaaacag tctctgaatg
    15781 cccgcaacgg aacgtccgat tccgcgccgt agcagttggc gtaaatttcc agggcctctc
    15841 ccctgtgatc catcccgaaa atctgcctca tcagggctgt ctttcccacg cccacctcgc
    15901 cttctatgat cacagacctg gcgtcctcat tgctgagaaa caggaaaatc tgctcgtcaa
    15961 cagcctgtat ctccgccagg cggccgaaaa acgcctcctt tgacgtttgg cttctcagag
    16021 aagacacctc ttttctgtgg agcagcgtct gaaacagaac ctctgcctgg tgggacggtt
    16081 cctcatccag atcctccttc aggcggcggg catactcctg atacagcttc actccccagt
    16141 cgtatttttc cgcctgcccg taaagcctca tgccggtcag aaccatctcc tcatcccacg
    16201 ggctccaatg cttccatgtg tcgattagga ggcggatccg ctccggattt ctgactgcgg
    16261 acggttcctc cagctgcacc ttcagctccc gcaggattct ggctgtctgc tgatttcttt
    16321 tttcttccac ccaatcctca aactccgggc agtccttcag ataaaaaaat ccaggaatct
    16381 ctcctggcaa agggaaaaat cacgttccgg catatcccag tctgtcttaa tctccacccg
    16441 ctgattgagc tttaaatcat ttctgccctg gaggacaatc acttcctccc ccaaaagctt
    16501 tctgagctga aacagagcct gcctcaggtt tttccggccg gaggcctcgt ccccggatcc
    16561 ccagaacagg gagaccagtt cgtcccggtt cgtgtgcttt tccacgcaca gataataaaa
    16621 aatcccctct gccttcctgt aaggaaaccg aaccggctcc cgatccctgc aaacacccgg
    16681 tatccccaga agcgtcactt catattccaa tccatttccc tccccttacc tttcctgctc
    16741 ttctgaaacc caccccgttt caggccggac gcctctgtcc gccttctttg gcaggcagag
    16801 ctccttctgg ggaatattat atcagagtcc tctcctccct acaatttatt tcttccacac
    16861 aatcactgcc ttgaacaagt ctgcctccgt ttccacctgg aagcttccct tctgaagctc
    16921 cacaaagctc ttcacaatcg ccaggcccag gccggatcct tccgtatttc tggactgatc
    16981 accccgcaca aaacgtcctg tcagctcccc ggcgtctttt ggaagctcag aggccgagat
    17041 atttttcatg gagattctca cttctccgcg gttttccctg ttctccccgg cctccgaagc
    17101 tgcgccgccc tcgtctgcct ccggcatttc tgtctcctca atctccacat aagccctggt
    17161 tcccggcatt ccgtatttgg ctatgttgac cagcagattt tcaaaaatcc gataggtttt
    17221 ttcgctgtca agagtcagcg ccaccctttt ctccggaagc tgaaaacgaa aatcaacccc
    17281 gctgtctgaa agctgctctg aaagctccag cttcacctgc ttcatcaggc ttaccacgtc
    17341 cacttccatc agattcagct tcatggtctg gctgttggcc ttgctgacct cgaacagatc
    17401 ctcaatcaga gccttcaggc gcagggattt gcgttccagc acctgaacgt actcctccct
    17461 ctcctggttt gtaataccag gttcctttaa aaggttaaca taagtaatga tcgctgtgag
    17521 aggcgtcttc aaatcatggg aaacattggt aatcagttcc gttttcatcc gctggctctt
    17581 cacctcggcg tccacggcct tcttaaagcc ggactgaatc tttcctatct cccttcgaaa
    17641 cggttcaaac actcccagat cctctgtaat ctccacatcc aggttgcctt ccgccagctc
    17701 atttgtcacc tttaaaagat tctggtactt ttcccgcacc cggccatagg ccttctgtaa
    17761 aatcacataa agcaccgccg agtaaaccag gaggccgaaa atcccgtaaa accacaggct
    17821 gcacagcacg gtcagcaaaa taaagttaat tcctacaatc tttaaaatac ttctggtcga
    17881 tttctcattg aagttaatct gctccagctc ccggcaggtc ctggacgccg cctttttaag
    17941 cgcccttcca agctttcctg taagcgtcct ctccttaaac catctgactg gccccacggt
    18001 aaagaaggac atggccgttt ccatcatcca gaagagcgcc agccccataa aaagccatgc
    18061 accgtaattg agagccatca taataacctg cgccgtctct gcatccaggt ggtaatactc
    18121 tgttgtcaaa accgccatcg tctcgccgct taaggacgcg catgccatgc ccggccccat
    18181 gccggaaccg atggacgccc ccagaatcat gaatcctgcg aaaagcatga tttcaaaggg
    18241 agccttgaac aggacagatt ccgtcatttt gagaggcttc actgccgcga acactgccgc
    18301 cgacacggtg acaagagccg ctgcgcacag ggtaataagt cccaaggccg cctgaactct
    18361 tccatatccc ggaagcaccc acacctcgtc gcctctgtgg cttacatgag cgccatagga
    18421 gacgtatccg ccgttatttt catagtaatc atagtcgctg atcacgacag aatcatagga
    18481 ctctgtttca taatcatact ccgcctcact gccggaagag cctgtgagct gttcccactc
    18541 ttttgccgta aaaacccgct ttccctctgc catctccgag gaaagccagg gataaaacgc
    18601 catcacgcct gcggcgatga aagccgtaat caaaaacgcc agaaggattc ccgtccagga
    18661 tcccatcgct tttttctctc tactgctgtt tctcaatttt atagccaact ccccacacca
    18721 cctttaaata ttttggattt ctgggattga tttcaatctt ttcccgtatg tttctcacat
    18781 gtaccatcac tgtgtctgta ttgaccgccc gctcgttcca cacccgctcg tagatctcgt
    18841 ccgccgagaa cacccggccc ggatgcttca tcagaagaag gaggatttta aattccatgg
    18901 gagtggcctt cacaggagct ccgtccacaa atacctccac tgtgtcctca tgaagctcca
    18961 ggcctccaat ccggtatacc cgctcctcct gcgccctggc tgttccagac tgccgttcct
    19021 caagaaggcg cagaaagcgc tgataccggc gaagctgaga acccactctg gctaaaagct
    19081 ccataggcgt aaacggcttt gtcacatagt cgtccgcccc catgttaagc cccataatct
    19141 tgtccacctc ctccgatttg gcggaaagaa aaatcaccgg gaaatcgtat ttttccctca
    19201 gcttaatcac catagtaatc ccgtccatcc gcggcatcat cacatccaca atagccaggg
    19261 aaatatcctg ctcctcaatg attttaagtc cctctatgcc gtctgccgcc tgaaataccc
    19321 ggtatccctg gcctttcaaa aatatctcga ttccctggcg gatttcctta tcatcctcca
    19381 caattaaaat agttcctgcg tccgctcctg tctgaatttc catagctgcc tgtcatctcc
    19441 ataaatttct gattttttct gctcttttcg agtcttgttc cgttctgctc tgattatact
    19501 acatcttcgg aattcttccc aagcaatctg aaaaaactga atcagcaggt tcactgccgc
    19561 caccatgcct aaaacaggaa acagaacctc tgccagatcc catccattca tatccgtctc
    19621 cccctcttct gttttgatag ggccagtata gggcaaaaat ctaaacaggg aagacagaaa
    19681 aaatgaaaga ttttctaaag atttggatat cggaaaaaag agatattttt cttgttccac
    19741 ttgaagtcac cgaaaaatat ctcttttttc cagctaaggc gtggtttgaa gcaagatatt
    19801 tcatcatatt tttatatatt tgtatgttta tttt
//
LOCUS       DBMDUW010000046        19615 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1687_length_19615_cov_4.495080, whole genome shotgun sequence.
ACCESSION   DBMDUW010000046 DBMDUW010000000
VERSION     DBMDUW010000046.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 19615)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 19615)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19615
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1687_length_19615_cov_4.495080"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            89..1648
                     /locus_tag="ACZPCR_08995"
     CDS             89..1648
                     /locus_tag="ACZPCR_08995"
                     /inference="COORDINATES: protein motif:HMM:NF012464.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4368 domain-containing protein"
                     /protein_id="HIR1231048.1"
                     /translation="MSSQRKILLKYATDNGFPNPTFFIDDGVSGVTFDRPGWNEMIRL
                     AEAGKVQTVIVKDMSRMGRDYLKVGYYTESFFAERDIRYIAINDGVDSTKGDNDFTPF
                     RNLFNDFYARDTSKKIRAVMRSKGNAGEHLCTNPPYGYRKDPADKKKWIVDEEAAEVV
                     KRIFDLCIAGKGPMQIAKVLTADRVLTVKAYYAKRDGKTMPDNLYRWDYKSISGILER
                     PEYTGCTVNFKTYSKSHKLKKRLQNAPENQRIFPNTQPAIIEGKVFERVQELRANKRR
                     PAKTGRQGLFSGLLYCADCGEKLYFCTTNSFTPKQEHYVCSNYKSNTGTCSAHFIREE
                     TLKLFVRQRIFDVTAMFIDDIQGFQKIVYQQRFTEAEKAVKRQKKELEQARKRITELD
                     RIFKRIYEDDINGTISHERFLKLSAEYEAEQKELTEFVQKEQAAVDTYEQDKSDFDSF
                     AAIIRKYVGIRELTPTIVNEFVKKIIVHAPDKSSGHRRQKIQIVWNFIGELEQDENKQ
                     TIERQRKSKTA"
     gene            complement(1883..3076)
                     /gene="tuf"
                     /locus_tag="ACZPCR_09000"
     CDS             complement(1883..3076)
                     /gene="tuf"
                     /locus_tag="ACZPCR_09000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006568224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HIR1231049.1"
                     /translation="MAKAKFERSKPHCNIGTIGHVDHGKTTTTAAITKVLAARVAGNA
                     QVDFENIDKAPEERERGITISTAHVEYQTEKRHYAHVDCPGHADYVKNMITGAAQMDG
                     AILVVAATDGVMAQTREHILLSRQVGVPYIVVFMNKCDMVEDEELLELVEMEIRELLN
                     EYEFPGDDTPIIQGSALKALEDPNGEWGDKIMELMDAVDSYIPDPERDTDKPFLMPVE
                     DVFSITGRGTVATGRVERGTLHVSDEVEIVGIHEDVRKVVVTGIEMFRKLLDEAQAGD
                     NIGALLRGVQRNEIQRGQCLVKPGSVKCHNKFTAQVYVLTKDEGGRHTPFFNNYRPQF
                     YFRTTDVTGVCELPAGTEMCMPGDNVEMTVELIHPVAMEQGLRFAIREGGRTVGSGRV
                     VSILD"
     gene            complement(3236..5356)
                     /gene="fusA"
                     /locus_tag="ACZPCR_09005"
     CDS             complement(3236..5356)
                     /gene="fusA"
                     /locus_tag="ACZPCR_09005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HIR1231050.1"
                     /translation="MAGREYPLERTRNIGIMAHIDAGKTTTTERILYYTGVNYKIGDT
                     HEGTATMDWMAQEQERGITITSAATTCHWTLQENCKPKEGALEHRINIIDTPGHVDFT
                     VEVERSLRVLDGAVGVFCAKGGVEPQSENVWRQADTYNVPRMAFVNKMDILGADFYGC
                     VEQIKTRLGKNAICLQLPIGKEDSFKGIIDLMEMKAYIYNDEKGEDISITDIPEDMKD
                     DAELYRTELVEKICELDDDLMMQYLEGEEPSVDELKKALRKGTCECQAIPVCCGTAYK
                     NKGIQKLLDAVIEYMPSPLDIPAIKGTDLEGNEIVRESSDDEPFSALVFKIMTDPFVG
                     KLAYFRVYSGTLNSGSYVLNATKGKKERVGRILQMHANKRQELDKVYSGDIAAAIGFK
                     FSGTGDTICDEQHPVILESMEFPEPVIDIAIEPKTKAGQQKMGEALAKLAEEDPTFRA
                     HTDHETGQTIISGMGELHLEIIVDRLLREFHVEANVGAPQVAYKETFTKAVDQEYKYA
                     KQSGGRGQYGHCKVKFEPMDANAEELFKFESAVVGGAIPKEYIPAVGEGIEEASKAGI
                     LGGFPVLGVHATVYDGSYHEVDSSEMAFHIAGSMCFKEAMKKANPVLLEPIMKVEVTM
                     PEEYMGDVIGDINSRRGRIEGMEDVGGGKLIKAFVPLSEMFGYSTDLRSRTQGRGNYS
                     MFFEKYEQVPKSVQEKILSEKAGK"
     gene            complement(5372..5842)
                     /gene="rpsG"
                     /locus_tag="ACZPCR_09010"
     CDS             complement(5372..5842)
                     /gene="rpsG"
                     /locus_tag="ACZPCR_09010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013274355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HIR1231051.1"
                     /translation="MPRKGHTQKRDVLADPLYNNKVVTKLINNIMLDGKKGVAQKIVY
                     GAFDRVAAETGKDAVEVFEEAMNNIMPVLEVKAKRIGGATYQVPIEVKPERRQALALR
                     WITLYSRKRGEKTQEERLAKEILDAANNTGASVKKKEDMHKMAEANKAFAHYRF"
     gene            complement(6158..6577)
                     /gene="rpsL"
                     /locus_tag="ACZPCR_09015"
     CDS             complement(6158..6577)
                     /gene="rpsL"
                     /locus_tag="ACZPCR_09015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004842433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HIR1231052.1"
                     /translation="MPTFNQLVRKGRQTSEKKSTAPALQKGYNSLQKRATNVSAPQKR
                     GVCTAVKTATPKKPNSALRKIARVRLSNGIEVTSYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGTRYHIIRGTLDTAGVANRKQARSKYGAKKPKDKK"
     gene            6933..7874
                     /locus_tag="ACZPCR_09020"
     CDS             6933..7874
                     /locus_tag="ACZPCR_09020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HIR1231053.1"
                     /translation="MKLVIIEPLGVEQEKLLSMAAEQLPESVEVVYYDTRVTDTETLI
                     ERGKDADIIAVSNLPLNADVIDGCKNLKMLSVAFTGVDHIALDACRRNGVLVSNCAGY
                     STAAVADLVFGLLISLYRNIPACNEVVRREGTKDGLVGFELEGKKFGVVGTGAIGLRV
                     AAIAQAFGCEVLAYSRTKKDVPGIAYTDLDTLLSQCDIVSLHTPLNDSTRGLIGKEQL
                     ALMKKNAVLINTARGPVVDSQALAEALNEERIAGACIDVFETEPPVKKEHPLLNAKHV
                     IATPHAAFATKEALVKRAVIVFDNITAWLNNAPQNVM"
     gene            8126..9664
                     /locus_tag="ACZPCR_09025"
     CDS             8126..9664
                     /locus_tag="ACZPCR_09025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006778538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0071705 - nitrogen compound transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BCCT family transporter"
                     /protein_id="HIR1231054.1"
                     /translation="MNEPHSDNKKLAARLDIMPMAVSLALILALCLAFFLAPEQSKHV
                     LDSVRFFIGEEFGVYYLAVGLGIFLLSLYLAFSPFGTIQLGAPGEKPQYSAFSWGAMM
                     FTSGLAADILFYSLCEWILYANDPHMAEMGSIQDWSSVYPLFHWGPIPWSFYVVLACA
                     FGFMLHVRKCRKQKYSEACRPILGSLTDKAPGRLIDLLAVFALLAGTATTFSLATPLM
                     SQTAASLLHVESSKWITIGILIVTCIVYTFSVVRGMKGVMKLASSCVYLFFALLAYVF
                     LAGGETRYIVETGFSAVGTLIQNFFTLATFTDPQRTTSFPQTWTMFYWAYWMVWAVAA
                     PFFIGSISKGRTVKQTILGGYVFGLGGTFTSFIILGNYSLGLQVSGRLDVMGIYNAGQ
                     DLYATIIAVINTLPMAQIVLVLLALAMVTFYATSFDAIALVASAYSYKEIPDGEEPHM
                     GVKVFWSLMLILLPIALVFSDSSMANLQTVSIIAAFPLAAVILLIVASFLKDGKKYLE
                     ENRK"
     gene            complement(9974..12118)
                     /locus_tag="ACZPCR_09030"
     CDS             complement(9974..12118)
                     /locus_tag="ACZPCR_09030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002601519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HIR1231055.1"
                     /translation="MDMIQALASELQIGRHQAEAAVRLIDEGNTIPFIARYRKEATGS
                     LNDEILRNLDERLKYLRNLEDRKNQVIASIREQEKLTPELEKQISDAATLVAVEDLYL
                     PYRPKRKTRAGTAREKGLLSLSDKIWDQSLTQPALAEAEQFISEEKGVADAKEALNGA
                     RDILAERIAETAEFRTYIRKAVLQEGVIESSAKNEKEKSVYEMYYHFSEPVKKAAGHR
                     ILALNRGEKEKLLTVKIVVPEEKILRYLEKQIITKNNEYSEPVLREAAADSFSRLIGP
                     AIEREVRGSLTEKAEAGAVQVFGKNLKQLLMQPPVAGRVVLGWDPAFRTGCKLAVVDE
                     TGKVLHTVVIYPTAPQNKVEESKRILKDLIKKYHISLISVGNGTASRESEQVIVELLK
                     EIPEQVQYVIVNEAGASVYSASKLATEEFPKFDVGQRSAVSIARRLQDPLSELVKIDP
                     KSIGVGQYQHDMNQKNLSEALQGVVEDCVNSVGVDLNTASASLLSYISGISKTVAKNI
                     VAYREENGVFKTRRELLKVPKLGPKAFEQCAGFLRIQGGKNPLDATSVHPESYQAAET
                     LLARLGYNVKELSKDGFAGIGRKIGDYSRLSSELSIGEITLRDIVKELEKPGRDPRDE
                     MPKPILRTDVLDIKDLKPGMILKGTVRNVIDFGAFVDIGVHQDGLVHISQMTERYIKH
                     PLEAVSVGDVVEVQVLEVDQEKKRIGLTMKIK"
     gene            complement(12345..13553)
                     /locus_tag="ACZPCR_09035"
     CDS             complement(12345..13553)
                     /locus_tag="ACZPCR_09035"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003502902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HIR1231056.1"
                     /translation="MLVVKKFGGSSVADTERIFNVARRCIEDYNRGNDVVVVLSAMGK
                     TTDGLIARAHEISDHPPKRELDMLLTTGEQVSVALMAMAIQSLGVPAVSLNAAQIRMK
                     TTSAYGQAKLKRIDTERIKNELDARKIVVITGFQGINKFDDMTTLGRGGSDTTAVALA
                     AVLHADTCEIFTDVDGVYTADPRIVPNARKLPEISYDEMLEFASLGAKVLHNRSVEMA
                     KRYNVQLVVLSSLVRTEGTVVKESTKMEKMLVSGVAADKNTARISVIGVLDEPGIAFK
                     VFNLLARHHINVDIIIQSVGQEGRKNISFTVARTDLQEAMTVLNENRESLTAQSVECA
                     ADVAKISIIGAGMTSNPGVAARMFEALYSANINIRMIATSEIRITVLIDEKDTNRAMR
                     VVHDAFSLGD"
     gene            complement(13609..14823)
                     /locus_tag="ACZPCR_09040"
     CDS             complement(13609..14823)
                     /locus_tag="ACZPCR_09040"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002576314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HIR1231057.1"
                     /translation="MIYAAVMGYGTIGSGVAEVLEKNRDVITARTKEEIQVKYILDLR
                     EFPGDPNEDKVIHDFSVIEQDEDVKIVVETMGGVRPAYDFVKASLLAGKHVVTSNKAL
                     VAACGTELLQIARDKGLNFLFEASVGGGIPLIRPLTGALAGERIVEISGILNGTTNYI
                     LTKMAKEGQTFEEALRKAQELGYAERNPESDVEGYDTCRKISILTALATGREVNYEDV
                     YTEGITAVTDTDFRYAAALGTCVKLFGSSRMEDGRVSVFVCPMMIPQENPLSSVSDVF
                     NAVMVKGNMAGTLMFYGSGAGKRPTASAVVADIMETAMNMDRNLPFGWGQERQTLTPV
                     EKTEFSYFLRFEGSAQEKKAEIEAAFGPARFVELPGMDEFAVLTGKMTEEHYRKVSAA
                     FGDIRQMIRAQI"
     gene            complement(14830..15273)
                     /locus_tag="ACZPCR_09045"
     CDS             complement(14830..15273)
                     /locus_tag="ACZPCR_09045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HIR1231058.1"
                     /translation="MEERTKYFVLKQKAVPEVLLKVVEAKRLLESEKAMTVQEASDRV
                     GISRSSFYKYKDDIFPFHDNAKGRTITLVLQMDDERGLLSDILHIVAVYKANILTIHQ
                     SIPVGNLASLTLSVEVRPDTGDISRMVEEMEAQKGIHYVKIIARE"
     gene            complement(15532..16648)
                     /gene="prfB"
                     /locus_tag="ACZPCR_09050"
     CDS             complement(join(15532..16572,16574..16648))
                     /gene="prfB"
                     /locus_tag="ACZPCR_09050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_156797306.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HIR1231059.1"
                     /translation="MVELDQFKYTLSTYEDTLVEVRDSLDLDGKVKRIDELDKSMEEP
                     GFWDDPETSTRLMRESKNLKDTVESYNKLEQEYEDIQVMIEMGYEENDPALVPEIRDM
                     MDDFVEKLETIRIQTLLSGEYDNNDAILKLNAGAGGTEACDWCSMLYRMYQRWADRKG
                     FATSVIDYLDGEEAGIKSITLKVAGENAYGFLKSERGVHRLVRISPFNSAGKRQTSFV
                     SCDVMPDIKEDLDVEINLDDLRIDTYRSSGAGGQHINKTSSAIRITHIPTGIVVQCQN
                     ERSQFQNKEVAMQMLKAKLYLMKQEENAEKLSDIRGDVKDINFGNQIRSYVMQPYTMV
                     KDHRTGAESGNVNAVLDGDIDSFISAYLKWINLDSKK"
     gene            complement(16871..19609)
                     /gene="secA"
                     /locus_tag="ACZPCR_09055"
     CDS             complement(16871..19609)
                     /gene="secA"
                     /locus_tag="ACZPCR_09055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HIR1231060.1"
                     /translation="MNLIEKVFGTHSDRELKLIYPIVDKIVALKPEMEKLTDEELRDN
                     TRKFKERLANGETLDDLLPEAFATVREAAKRVLKMEHYPVQLIGGIVLHQGRIAEMKT
                     GEGKTLVSTCPAYLNALAGKGVFIVTVNDYLAKRDAEWMGEVHRFLGLTVGVVLNAMT
                     PQERKAAYGCDITYVTNNELGFDYLRDNMAIYKEQMVLRNLDYAIIDEVDSVLIDEAR
                     TPLIISGQSGKSTKLYEVCDILAKQLEQGEASAEFTKLSAIMGEEIEETGDFVVNEKD
                     KVVNLTLEGVKKVEKYFNIENLADPENLEIQHNMIMALRANYLMFRDKDYVVKDNEIL
                     IVDEFTGRIMPGRRYSDGLHQAIEAKEHVEVKRESRTLATITFQNFFNKFTKKAGMTG
                     TAQTEEKEFRNIYQMDVIVIPTNRPVLRIDKNDAVYKTKKEKFHAVVEEVCAAHEKGQ
                     PVLVGTITIETSELLSKMLKKRGIPHKVLNAKFHELEAEIVADAGIHGAVTIATNMAG
                     RGTDIKLDDESKALGGLKIIGTERHESRRIDNQLRGRAGRQGDPGESRFYISLEDDLM
                     RLFGSEKLMGMFNALGVPENEQIEHKMLSKAIENAQMKIETNNYGIRENLLKYDEVMN
                     EQREVIYEERRRVLDGENMRNVIMKMITDIVENAVDLSISDEQTPEEWNLTELNSLLL
                     SIIPLPPITLNADQKKMKKNELKHMLKESATKLYEAKEAEFPQAEQIRELERVVLLKV
                     IDNKWMAHIDDMDQLREGIGLQAYGQKDPLVEYKMSGYEMFDAMTASIREDTVRTLYH
                     IRVEQKVEREPAAKVTGTNKDASPQAPQKRETRKIYPNDPCPCGSGKKFKQCCGRQML
                     ADMQERKEKEQQKKERRDERRKEHQAEKAARRAEYQERKAERLAQKAANSEENLEE"
BASE COUNT         4438 a         5442 c         4364 g         5371 t
ORIGIN      
        1 ccattctgcg gctctgtgtt tattatatct gagctattca cagtaaagtt ggacatttgt
       61 attcagcggg agaaaataac cttgacaaat ctcgtctcag aggaaaatcc tgcttaaata
      121 cgcaacggac aacggtttcc ctaatcctac atttttcatt gacgacggcg tttccggtgt
      181 aactttcgac agacccggtt ggaatgagat gatacgcctt gcagaagcag ggaaagtcca
      241 gactgttatt gtcaaggata tgtcccgcat ggggcgtgat tatctgaaag taggatatta
      301 caccgaaagt ttctttgccg agcgtgatat tcgctatatc gcaatcaatg acggcgtgga
      361 cagtacaaag ggggacaatg atttcactcc tttccgaaat ttgttcaatg atttttacgc
      421 acgagatacg agtaagaaaa tcagagccgt tatgcggtca aagggcaatg caggagaaca
      481 cctctgtacc aacccgccct atgggtacag gaaagacccg gcagataaaa agaaatggat
      541 tgtggacgaa gaagccgccg aggtggtaaa gaggattttc gatttgtgca ttgcaggaaa
      601 aggaccaatg cagatagcaa aagtgctgac agcagacagg gttttgacgg tcaaagccta
      661 ctatgcaaag cgtgacggaa agactatgcc ggacaatctg tatcggtggg attacaaatc
      721 catatcgggg attttggaac gcccggaata tacaggctgt accgtcaact tcaaaaccta
      781 ttccaaatct cacaaattga aaaagcgtct gcaaaacgct cccgaaaatc agcggatttt
      841 ccccaatacc cagcctgcca ttatcgaggg aaaagtcttt gaacgggtgc aggaactacg
      901 ggcaaacaaa cgccgccctg caaagacagg gcggcaagga ttgttctctg gcttgctcta
      961 ttgcgctgac tgtggcgaaa agctgtactt ctgtacaaca aacagcttca cgccgaaaca
     1021 agagcattat gtctgctcta actacaagag caatacaggt acttgctctg cacatttcat
     1081 cagagaagaa accttgaagc tgtttgtccg gcagaggatt tttgatgtaa cggctatgtt
     1141 cattgatgat atacagggtt ttcagaaaat cgtatatcag cagagattta cagaagcgga
     1201 aaaggcagta aagcggcaga aaaaagaact ggaacaggca aggaaacgga ttaccgaact
     1261 tgaccgtatt tttaagcgga tttatgagga cgatataaac ggcacaatca gccatgagcg
     1321 atttttgaag ctgtccgcag agtatgaagc ggagcaaaag gaattgacgg agtttgtcca
     1381 gaaagagcaa gccgctgttg atacctacga acaggacaag tctgattttg atagcttcgc
     1441 cgctataatc cgcaagtatg taggaatacg ggaactaacg cccactattg tcaatgagtt
     1501 tgtaaagaaa atcatcgtcc atgcgccgga taaatcaagc ggacaccgca gacagaagat
     1561 acagattgta tggaacttta tcggagaact ggaacaggac gagaataagc agaccattga
     1621 acggcagaga aaaagcaaga cagcatagca aaccgctatg ctgccctgca acttaacaat
     1681 tacttcctta tgggtgtgcc cctttcgcat acaccctctt ttgatcaaaa aacgctgcaa
     1741 agcccgaaag ccttgcagcg ccttttacac tgtctgagca agatactgcc ccggcctgca
     1801 tacacaaaac gcgtatgcag agcaggaaag catcatatta ttaataagca catattgtgc
     1861 aaagattcaa tcgtcctgtt gattagtcaa ggatagaaac tactctacca gaaccaactg
     1921 tacggccgcc ctcacggata gcgaaacgaa gtccctgctc catagctact ggatggatca
     1981 gctcaactgt catctctacg ttatcgccag gcatgcacat ctctgtacca gccggtaact
     2041 cgcaaacgcc tgtaacgtct gttgttctga agtagaactg cggacggtag ttgttgaaga
     2101 atggtgtatg acggccaccc tcgtcctttg taagaacgta aacctgagct gtgaacttgt
     2161 tatggcactt tacagaacct ggcttaacaa gacactgtcc tctctggatc tcgtttctct
     2221 gaacaccacg gagcagcgca ccgatgttgt caccagcctg agcctcatca agaagcttac
     2281 ggaacatctc gataccagtt acaacaacct tacgaacgtc ctcgtgaata ccaacgatct
     2341 caacctcgtc agatacgtga agtgtaccac gctctacacg gcctgtagca actgtaccac
     2401 ggcctgtgat ggagaatacg tcctcaactg gcataaggaa tggcttatct gtgtcacgct
     2461 ctggatccgg aatgtagctg tcaacagcat ccataagctc catgatcttg tcgccccact
     2521 cgccgttcgg atcctcaaga gccttaagag cagaaccctg gatgattggt gtatcatcgc
     2581 ccgggaactc gtactcgtta agaagctcgc ggatctccat ctctactaac tcaagtaact
     2641 cctcgtcctc aaccatgtcg cacttgttca tgaatacaac gatgtaagga acgcctacct
     2701 gacgggaaag aaggatgtgc tctcttgtct gagccataac accatctgta gcagcaacta
     2761 caaggatagc gccatccatc tgagctgcac cagtgatcat gttcttaacg tagtcagcat
     2821 gtcctgggca gtcaacgtga gcgtagtgtc tcttctctgt ctggtactct acgtgagctg
     2881 tagaaatagt aattccacgc tctctctcct ctggagcttt atcgatattc tcaaagtcaa
     2941 cctgtgcatt acctgcaact cttgcagcta atacttttgt aatagcagca gttgtagttg
     3001 ttttaccatg gtcaacgtgt ccgatggtac caatgttaca atgtggtttg cttctttcaa
     3061 actttgcttt tgccatttta taacgtcctc cttaaatttg cccggaaagg gctatatgat
     3121 atatgttagg ctgtttcaat tatattctat cagaatatct ttttcaagcc tattttatac
     3181 tcccccggca gttttttcct gccggaagga gcacttggaa acgtgatttc ctgaattact
     3241 ttccagcctt ctcggaaagg atcttctcct gtacgctctt cggtacctgc tcgtacttct
     3301 cgaagaacat ggagtagttt ccacgtccct gtgttctgga acgaaggtct gtagagtatc
     3361 cgaacatctc agaaagcgga acgaatgcct tgatcagctt gccgcctccg acatcctcca
     3421 taccctcgat acggccgcgg cgggagttga tatctccgat aacgtcgccc atatactcct
     3481 caggcatagt aacctctacc ttcatgatcg gctcgagaag aactgggtta gccttcttca
     3541 tagcctcctt gaaacacatg gaacctgcaa tgtggaacgc catctcagag gagtcaacct
     3601 cgtggtagga accatcatat acagtagcgt gaacgccaag taccgggaat cctccaagga
     3661 taccagcctt ggaagcctct tcgataccct cgccgactgc cgggatgtac tccttcggaa
     3721 tagcaccgcc gactacggca gactcgaact tgaacagctc ctcagcgtta gcgtccatcg
     3781 gctcaaactt aactttacag tgtccgtact gtccgcgtcc accagactgc ttagcatact
     3841 tgtactcctg atcaacagcc tttgtaaagg tctccttgta agcaacctga ggtgcgccta
     3901 cgttagcctc tacgtggaac tcacgaagca gacggtctac aatgatctcc aggtgaagct
     3961 cacccatacc ggaaataatt gtctgtcctg tctcatgatc tgtgtgagcg cggaaggtcg
     4021 gatcctcctc agcaagcttt gctaaagcct cgcccatctt ctgctgtcca gcctttgtct
     4081 tcggctcgat agcgatatcg ataaccggct ccgggaactc catggactcc aggattaccg
     4141 gatgctgctc gtcacagatt gtatcacctg ttccggagaa cttgaatccg attgctgcgg
     4201 cgatatcgcc ggagtaaacc ttgtcaagct cctgtctctt gttggcgtgc atctgaagga
     4261 tacggccaac acgctctttc ttgccctttg tggcgttgag aacgtaggaa ccggaattta
     4321 atgtaccgga atatacacgg aagtaagcaa gcttacctac gaacgggtca gtcatgatct
     4381 tgaatacaag agcggagaat ggctcgtcgt cggaagactc tctcacaatc tcgttgccct
     4441 caaggtctgt acctttaata gccgggatat caagcggaga cggcatatac tcgataacag
     4501 cgtcaaggag cttctgaata cccttgttct tgtatgctgt accgcagcat accgggatag
     4561 cctggcactc gcaggttccc tttctcaggg ccttctttaa ctcgtcaacg gaaggctcct
     4621 caccctccag gtactgcatc attaaatcgt cgtccagctc gcagatcttc tctaccagct
     4681 ctgtacggta aagctctgca tcgtccttca tatcctccgg gatatctgta atggaaatgt
     4741 cctcgccctt ctcatcgttg tagatgtaag ccttcatttc catcaggtcg ataattccct
     4801 tgaagctgtc ttcttttcca ataggaagct gtaagcagat agcgttcttg ccaagtcttg
     4861 tcttgatctg ctctacgcag ccgtagaaat ctgctcctaa gatatccatc ttatttacaa
     4921 atgccatacg gggaacattg tatgtgtctg cctgacgcca tacgttctca gactgtggct
     4981 caacaccgcc ctttgcacag aacacgccta cagcgccgtc cagtacacga agagaacgct
     5041 caacctctac agtgaagtca acgtgtcctg gagtatcgat gatgttgata cggtgctcca
     5101 gagcgccttc cttcggcttg cagttctcct gcagtgtcca gtggcaagta gtagccgctg
     5161 aagtgattgt gatacctctc tcctgctcct gagccatcca gtccatggta gcagtacctt
     5221 catgagtatc accgatctta tagtttacac cagtgtagta cagaatacgc tcagttgttg
     5281 tcgtcttacc ggcatcgata tgagccataa ttccgatgtt tctggttctc tctaacggat
     5341 attctcttcc agccaaagct ttttcctcct attagaatct gtaatgagca aatgccttgt
     5401 tagcctctgc catcttatgc atgtcttctt tcttctttac agatgcgcct gtgttgttag
     5461 ctgcatccag aatctctttt gcaagtctct cttcctgagt tttctcgcct ctcttacggg
     5521 agtagagtgt gatccagcga agtgcgagag cctgtcttct ctccggctta acctcgatcg
     5581 gaacctggta tgtggcacca ccgatacgtt ttgccttaac ctcgagaact ggcatgatgt
     5641 tgttcatagc ctcctcgaat acctcgacag cgtccttgcc tgtctcagct gctacacggt
     5701 cgaatgcgcc gtaaacgatc ttctgggcaa ctcccttctt accgtctaac atgatgttgt
     5761 tgattaattt agtaacaacc ttgttgttgt acagcggatc tgctaatacg tctcttttct
     5821 gagtatgtcc tttacgtggc acgttacttc cctccttaat atggctgcct gaaactgatt
     5881 tacgctgcaa atgcaggcag atttcgtttc cgcagcgttt cattagatct taggtactcg
     5941 tgcattgagc gcttggtgag gtctctgcga acctagcgtt caagcacgcc tgcgaagcca
     6001 gcgcgtcttc tgcgcgcgcc gctgagcatg gcgcttcctt aatgcgcttc cctcttcttc
     6061 tctctgcacg tgtcgtgctc ggttcttatg attaaacctg caacctacaa gtcaatatca
     6121 aagtccggca ctaaaattca attgaatttt cacctaatta tttcttgtct ttcggcttct
     6181 tagcgccgta cttggaacga gcctgctttc tgttggctac gcctgctgta tcaagtgtac
     6241 cacggataat gtggtatctt gtacctggta agtccttaac acggccgccg cggataagaa
     6301 caacgctgtg ctcctgtaag ttgtgtccct cacctggaat gtagcttgtt acctcgattc
     6361 cgttggacag acgcactctg gcaatctttc taagagctga gtttggcttc ttaggtgtag
     6421 cagtcttaac tgctgtacaa acacctctct tctgaggagc agatacgttt gtagctctct
     6481 tctgtaaaga gttgtatccc ttctgcagag ccggtgctgt ggatttcttc tcagatgtct
     6541 gtcttccctt tcttactaac tggttaaatg taggcatcct tttcacctcc tgtgatattg
     6601 tctgttggtt gcggcttctt ctattctaaa gccttgattt tacgcacaaa aatactgcat
     6661 gagaattttg cacgcttact cattatatca gattgtcggc ttctgtcaag gcttccggaa
     6721 gatttttttc acggattttc cttgatattg taggggttcc ggagttcctt cccgctttgc
     6781 aatggatcga aaaaacagtt tttataccca tgtctgctgt gattaagcgc aactgactgt
     6841 ttcctgacgg ctttctttat gataaactgt ctatataaga aacatttatt acttaagaaa
     6901 catttattac tgatgaaaga aggaacccag ttatgaagct tgttatcatc gaacctttag
     6961 gcgtggagca ggaaaagctc ctttccatgg cggcagagca gctgccggag tctgtggagg
     7021 tggtttacta tgacacccgc gtcacagaca ctgaaacact gattgagcgg ggaaaggacg
     7081 ccgatatcat cgcggtgtcc aatcttccat taaatgctga tgtcattgac ggctgtaaga
     7141 acctgaaaat gctgtccgtg gcctttaccg gggtggatca catcgctctg gacgcctgca
     7201 gacgaaacgg cgttctggtg agcaactgtg ccggttactc caccgccgct gtggcggatc
     7261 tggtattcgg ccttctgatc tctttatata ggaacattcc cgcctgcaat gaggtggtga
     7321 gaagagaggg aaccaaggac ggactggtgg gatttgagct ggaaggcaag aaattcggcg
     7381 tagtgggaac aggcgccatc ggtcttcggg tggcagccat tgcccaggcc tttggatgtg
     7441 aggttctggc atacagcagg acgaaaaagg acgttcccgg cattgcctac acagatctgg
     7501 acactctcct ttcccagtgt gacattgtat ctcttcacac acctttgaac gattccacca
     7561 gagggttaat cggaaaagaa cagctggccc tgatgaagaa aaacgcggtt ctcatcaata
     7621 cagcccgcgg cccggtagtg gacagtcagg cgctggcaga ggcattaaat gaggaacgga
     7681 ttgccggagc ctgcattgat gtctttgaga cagagccgcc tgttaaaaag gaacaccccc
     7741 tgttaaatgc caagcatgtc atcgccactc cccacgcggc ctttgctact aaggaagccc
     7801 tggtaaagcg ggcagtcatc gtctttgaca atatcaccgc atggctgaac aatgctcccc
     7861 agaatgtgat gtaagcctga tataaattgt atcaaattaa tatgtaattc caaaagctta
     7921 cacagatttg tcttacatag ctgctaaaaa gaatgttttt ctgctttgca atatgcacgg
     7981 ctgttaaaaa cattcttttt ttgccctgac gtcttgcatt tcctatgatt ccctgttata
     8041 atgttcaata tcttttattt taaatcaaaa atgaacattc agcagatata cgcactgctt
     8101 aataaaaccg aggaggtatc tttccatgaa tgaaccgcat tcagataaca aaaagctggc
     8161 cgcacggctg gatattatgc cgatggccgt ttccctggcc ctgattctgg ccctgtgcct
     8221 ggcctttttc ctggctccgg agcagtctaa acacgttctg gactctgtcc gcttctttat
     8281 tggggaggaa ttcggcgtct actatctggc cgtaggcctg ggcattttcc tgctgtcgct
     8341 ctatctggcc ttctccccct tcggaaccat ccagctgggg gcgccgggag aaaagcctca
     8401 gtattctgcc ttttcctggg gcgctatgat gttcacctcc ggtctggcgg ctgatatcct
     8461 tttctattct ctgtgcgagt ggattctcta tgccaatgat ccccacatgg cagaaatggg
     8521 atctatccag gactggtcca gcgtctatcc cctgtttcac tggggcccca ttccgtggag
     8581 cttctatgtg gtgctggcct gcgccttcgg ctttatgctc catgtgagaa aatgcagaaa
     8641 acagaaatat tccgaggcct gccgcccgat tctgggctcc ctgacagaca aggctcccgg
     8701 gcgtctcatt gaccttttag ctgtcttcgc tctgttagcc ggaaccgcca ccaccttcag
     8761 tctggccacc ccgctgatga gccagacggc tgccagcctg ctccacgtgg aaagctccaa
     8821 atggattacc attggaattt tgatcgtcac ctgcattgta tacacgttct ctgtcgtccg
     8881 cggcatgaag ggcgtcatga agctggcctc ctcctgtgtg tatctctttt ttgctctgct
     8941 tgcctatgtg ttcctggccg gcggagagac ccgttacatt gtggaaacgg gcttttcggc
     9001 agtcggaacc ctgattcaga atttctttac tctggctacc tttacggatc ctcaaagaac
     9061 cacctccttc cctcagacct ggaccatgtt ctactgggcc tactggatgg tgtgggcggt
     9121 ggccgctcca ttctttattg gaagtatctc taagggacgc accgtaaaac agacgattct
     9181 gggcggttat gtgttcggcc tgggcggcac cttcaccagc ttcattattc tgggcaatta
     9241 cagcctggga ctgcaggttt ccggacggct ggacgttatg ggaatctaca atgccggtca
     9301 ggatctctat gcaaccatca tcgctgttat caacaccctg cctatggcgc agatcgtgct
     9361 ggttcttctg gctctggcca tggtcacctt ctacgccacc agctttgatg ccatcgctct
     9421 ggttgcctcc gcctactcct acaaggagat tccagatggg gaggagcccc acatgggagt
     9481 aaaggttttc tggtccctga tgctgattct gctgcccatc gcccttgtct tttcagacag
     9541 ttccatggcg aatctccaga ccgtgtccat catcgcggcg tttcctctgg cagctgtgat
     9601 tcttctgatc gtagccagct ttttaaagga tgggaagaag tatctggagg aaaatcggaa
     9661 ataggattat tagaaagagg aagagtttcc ttgttccact taaagtcacc ggaaactctt
     9721 cctctttctt cctctatttt ctcttttctc tgaagctaag tcgctgaaaa actttccctc
     9781 ttcttttttc cttgttctgc ttaaagccac tagaaactct tctttcttcc tctattttct
     9841 cttttctctg aagctgagtc accggaaact ttctctcttc ttttttcttc cacctggtct
     9901 atacaagaga aaaggacgta tttttggtga cttttgtgga acaaaaaaat acgccctttt
     9961 ctctgatttt accttatttt attttcatgg tcagcccaat ccgcttcttt tcctggtcta
    10021 cttccagtac ctggacttcc acgacgtctc ctacgctgac tgcctccagc gggtgcttga
    10081 tgtagcgctc ggtcatctgt gagatgtgaa ccaggccgtc ctggtggacg ccgatatcca
    10141 cgaaagcgcc gaaatcaatg acgtttcgca cggtgccctt taaaatcatg cctggcttta
    10201 aatccttgat gtccagcacg tcggttctca gaatcggctt cggcatctcg tctctcggat
    10261 ctctgcctgg cttctccagc tcttttacaa tatcccgcag cgtgatttcg ccgatggaaa
    10321 gctcagacga caggcggctg taatcgccga ttttccgtcc gattcccgca aatccgtcct
    10381 tggaaagctc cttcacattg tagcccagac gtgcaagcag cgtttcggcg gcctggtagc
    10441 tctccggatg tacgctggta gcgtccagag gatttttccc tccctgaatg cgcaggaatc
    10501 cggcgcactg ctcaaaggcc ttcggcccca gcttcggcac ctttaaaagc tctcttcttg
    10561 tcttaaatac gccgttttcc tcccggtaag ccacaatatt tttcgctaca gtcttactga
    10621 ttcctgaaat gtagcttaag agggaggcag acgctgtgtt cagatccacg cccacgctgt
    10681 tgacgcagtc ctccaccacg ccctgcagag cctcgctcaa atttttctgg ttcatatcgt
    10741 gctgatactg tcccactccg atggatttag ggtcaatctt caccagctca gacaggggat
    10801 cctgaagccg tctggcaata gacactgcgc ttctctgtcc cacgtcaaac ttcgggaact
    10861 cctctgtggc cagcttgctg gcagagtaga cagacgctcc cgcctcattg acaatcacat
    10921 actgcacctg ctccggaatt tccttcaaaa gctccacaat cacctgctcc gattctctgg
    10981 acgccgttcc gtttcccaca gaaatcagag aaatatggta cttcttaatt aaatccttta
    11041 agatccgctt ggactcctcc accttattct ggggcgcggt agggtaaatc acaacggtgt
    11101 ggagaacctt tcccgtctcg tccaccaccg ccagcttgca gccggtgcgg aaagccggat
    11161 cccagcccag cacaactctg cctgccaccg gcggctgcat gagcagctgc tttaaatttt
    11221 tgccgaacac ctggacagcg cctgcctccg ccttctcagt cagacttcct ctgacctcgc
    11281 gctcgatggc cgggccaatc aggcggctga agctgtctgc tgccgcttcc ctgagtacag
    11341 gttcagaata ttcattattt tttgtaataa tctgtttttc cagatatctg agaattttct
    11401 cctctggaac aacaatcttc actgtgagaa gtttctcctt ctctccccgg tttagagcca
    11461 gaatcctgtg ccccgccgcc tttttcaccg gctcggagaa atgataatac atctcgtaga
    11521 cggatttttc cttctcattt ttagcggagg attcgatcac tccctcctga aggactgcct
    11581 ttctaatgta ggttcggaac tcggctgtct cagcaattct ttccgccagg atatctctgg
    11641 caccgttcag ggcctcctta gcgtcggcca ctcccttttc ctccgaaatg aactgctccg
    11701 cctcggcaag cgccggctgc gtcaggctct gatcccaaat cttatctgac agagaaagaa
    11761 gtcccttctc tctggccgtc ccggccctcg tctttctctt aggcctgtag gggagataga
    11821 gatcctccac agctaccagc gtcgcggcgt ctgaaatctg cttctccagt tccggtgtca
    11881 gcttctcctg ttctctaata gaggcaatga cctgattttt ccggtcttcc agatttctga
    11941 gatattttaa cctctcgtcc agatttctga gaatctcgtc gtttaacgat ccggtcgcct
    12001 cttttctgta cctggcaata aacggaatcg tatttccctc gtcaatcagc ctgacggcag
    12061 cctccgcctg gtgtcttcca atctgaagct ccgatgcaag cgcctgtatc atatccataa
    12121 taatttcctc atttccaaac ataatagacg tatcgccaaa ctgctgcgga cagattctgc
    12181 cgatacatct tctgcattgc ttattataat agattttaag agagggcgca actgaaacgc
    12241 cctggcagaa aacagattga aaacagatga aaaaaacagg cagggaagcg atccctgcct
    12301 gactttcaaa gatttttcca tcttttcgga ctttccagta tcaattaatc tcccagagaa
    12361 aacgcgtcgt gaaccacccg catggcccgg ttcgtatcct tctcgtcaat gaggaccgta
    12421 atacggatct ccgaggtggc aatcatgcgg atgttgatat ttgcgctgta aagggcctcg
    12481 aacatcctgg ccgcaactcc cggattgctg gtcataccgg ctccgatgat ggaaatttta
    12541 gccacgtccg cagcacattc taccgactga gcggtcaggg actccctgtt ctcgtttaag
    12601 acagtcatgg cctcctgaag gtcggttctc gccacagtga aggaaatgtt tttcctcccc
    12661 tcctggccca cagactggat aataatatcc acattgatat ggtgtctggc cagaagattg
    12721 aacaccttaa aggcgattcc cggctcgtcc agcactccta tcacggaaat tctggcggta
    12781 ttcttgtcgg ccgccacacc gctgactaac attttctcca tcttcgtact ctccttcaca
    12841 accgttccct cagtccggac aagacttgac agaactacta actgcacatt ataacgcttg
    12901 gccatctcca cagaacggtt gtgcagcacc ttagccccca gggacgcaaa ctccagcatc
    12961 tcgtcgtagg atatctccgg aagcttccta gcatttggaa caattctggg atccgccgtg
    13021 tacactccgt caacatccgt gaaaatctca caggtgtctg catgaaggac agctgccaga
    13081 gccaccgccg tagtgtcgga accgcctctg cccagagttg tcatatcgtc gaatttatta
    13141 atcccctgaa atcctgtgat aaccacaatc tttctggcat ccagctcatt tttaatgcgc
    13201 tctgtatcaa tccgcttcag cttcgcctgc ccataggcgg atgtggtttt catacggatc
    13261 tgggccgcgt tcagcgaaac agccggtact cccagagact gaatcgccat ggccatcaga
    13321 gccacagaaa cctgctctcc cgttgtcaga agcatatcca gctcccgttt cggcggatga
    13381 tcggagattt catgggccct ggctatcagc ccgtccgtcg tcttccccat ggcggagaga
    13441 accaccacca cgtcatttcc tctattgtaa tcctctatgc agcgccttgc cacattgaaa
    13501 atcctctccg tatcggcaac ggaactgccg ccgaatttct ttacgactaa catgcctttt
    13561 cctccatggt atccttgcca tccggcctgg cgcactgtgg ctgccgcgct aaatctgcgc
    13621 ccggatcatc tgcctgatgt cgccaaacgc cgcagatacc tttctgtaat gctcttctgt
    13681 cattttgccg gtgagcacgg caaattcatc catgccggga agctccacga accttgccgg
    13741 gccaaatgcc gcctcaatct ccgctttctt ctcctgggcg cttccctcaa accgcaggaa
    13801 ataggaaaat tccgtcttct ccaccggagt cagagtctgg cgctcctgtc cccagccaaa
    13861 cggaagattc cgatccatat tcatggcagt ttccataata tccgccacca ccgcgctggc
    13921 tgtaggccgc tttccggcgc cgcttccgta gaacatcaga gtcccggcca tgtttccctt
    13981 caccatcacg gcgttgaaca catcgctgac gctggagaga ggattctcct gaggaatcat
    14041 catagggcac acgaagacgg atactctgcc atcctccatc cggctgctgc cgaacagctt
    14101 gacacaggtt ccaagggcgg ccgcatacct gaaatctgta tctgtcacag ccgtaattcc
    14161 ttctgtatac acatcctcat aattgacctc tctgcctgtg gcgagggctg tcagaatgga
    14221 aatcttccgg caggtgtcat agccctccac atctgactcc ggattgcgct ctgcgtatcc
    14281 cagctcctgg gcctttctca gcgcttcctc gaaggtctgt ccctccttcg ccatcttggt
    14341 gagaatgtag ttggttgtcc catttaaaat tccgctgatt tccacaattc tctcgcctgc
    14401 cagagcccct gtcagcggcc ggattaacgg aattccgcct cccacgctgg cctcaaaaag
    14461 gaaatttaat cccttatctc tggcaatctg cagaagctct gttccgcagg cagccaccag
    14521 ggccttgttg gacgtcacca catgcttgcc cgccagcagg ctggccttga caaagtcgta
    14581 agccgggcgg acgcctccca tcgtctccac cacaattttt acgtcctcgt cctgctcaat
    14641 gacggaaaaa tcgtggatca ctttatcttc attgggatct cccggaaatt cccggagatc
    14701 taaaatgtat tttacctgta tctcttcctt ggttctggcc gtaataacgt ccctgttctt
    14761 ttccagaacc tccgccactc cagaaccgat tgtcccatac cccataactg ctgcataaat
    14821 cataatctat cactccctgg caataatttt cacatagtga attcccttct gcgcttccat
    14881 ctcctccacc attctggaaa tgtcccctgt atccggcctt acctccacgc tcagcgtcag
    14941 agacgccaga tttcccacag ggatactctg atgaattgtc aaaatattag ctttatagac
    15001 cgctacgata tggaggatgt cagagagcag tcctctttca tcgtccatct gaagaaccag
    15061 ggtgattgtt cgtcccttcg cattatcgtg aaagggaaaa atatcgtcct tgtacttgta
    15121 aaaggagctt ctgctgattc caaccctgtc cgaagcctcc tgaactgtca tagccttctc
    15181 tgattcgagc aggcgttttg cctccactac ctttaacagc acctccggca ccgccttctg
    15241 cttcaaaacg aaatattttg tccgctcttc cattcccatt cctctttcgc tcagctgcat
    15301 acagtctgcc tgcagcagct tattttaccg cgctctgtga ttcggatcaa aaacggccga
    15361 aggctctgcc tggaatccgc cggctttcca gctgaacgga tccctgcttt ctgccttcag
    15421 ccgccatttt ttccagccac cgtaccaatg gctgccgaat caaaatgtat gcgtgtgaaa
    15481 aacacttgta ctcacaggaa agatattatc atatttatcc agtatattca atcacttttt
    15541 gctgtccagg ttgatccatt ttaaataagc gctgataaag gagtcaatat cgccgtccag
    15601 aactgcgttc acatttccgc tctccgcccc ggtccggtga tcctttacca tagtataagg
    15661 ctgcatcaca taggaacgga tctggtttcc gaaattaatg tcctttacgt ctccgcggat
    15721 atcggaaagc ttctctgcgt tctcctcctg cttcatcagg tagagcttcg ccttcagcat
    15781 ctgcatcgcc acttccttat tctggaactg ggatctctca ttctggcact gcaccacgat
    15841 tcccgtagga atatgggtaa tccggatggc ggaagaggtc ttattgatat gctgtccgcc
    15901 tgcgccgctg gaacggtagg tatcgattct caaatcgtcc agattgatct ccacgtccag
    15961 atcctccttg atatccggca tcacatcgca ggatacgaaa gacgtctgcc tctttccggc
    16021 agagttgaag ggggaaattc ttaccagacg gtggacgcct ctctctgact tcagaaaacc
    16081 gtaggcattt tctccggcaa ccttgagggt aatggattta atgccggcct cctcgccgtc
    16141 cagatagtcg ataacagagg tggcaaagcc ctttctgtcc gcccatctct ggtacatccg
    16201 gtacaacatg ctgcaccagt cgcaggcctc tgtgccgccc gctcctgcgt tcagcttcaa
    16261 aatcgcgtcg ttattatcgt attcgccgga cagaagcgtc tgaatccgga tggtctccag
    16321 cttttccacg aaatcatcca tcatatcccg gatctcaggc accagggccg gatcattctc
    16381 ctcatagccc atctcaatca tgacctgaat gtcctcgtac tcctgctcca gcttattata
    16441 gctttccacg gtatccttga gattcttgga ctcccgcatc agtctcgtcg acgtctccgg
    16501 atcgtcccag aagcccggct cctccatgga tttatctaat tcgtcaattc gtttcacctt
    16561 gccgtccagg tcaaagtgaa tccctcactt ccaccagggt atcctcatac gttgacagtg
    16621 tgtacttaaa ctgatcaagt tcaaccatag cttcacccac tttcttattt tatatttccc
    16681 cttattctaa catgagcagg ggagattgcg caagattgtg aatgagaaag agaaactgtt
    16741 ttcttgttcc acttaaagtc accgaaaaca gtttctctct ctgctacact tccgcactaa
    16801 aaaaggaagc agagcaatgt tccggtggct tcccgctgga ataaggaaca tttctctgct
    16861 tccatcgatt ttactcttct aaattctctt cgctatttgc tgctttctgc gctaaccgct
    16921 ctgcctttct ctcctgatac tcggctctcc gggcagcctt ctctgcctgg tgctccttgc
    16981 ggcgctcgtc ccggcgttct ttcttctgct gctctttttc cttgcgctcc tgcatatccg
    17041 ccagcatctg gcgtccgcag cactgcttga atttctttcc ggaaccgcat ggacacggat
    17101 cgttcggata aatctttctg gtttctctct tctgcggagc ctgaggagac gcatccttat
    17161 tggttcccgt caccttggct gccggctctc tctccacctt ctgctctacg cggatgtggt
    17221 aaagggttct cactgtatcc tcgcggatgg aggccgtcat ggcgtcgaac atctcgtagc
    17281 cgctcatctt gtactcaacc agcggatcct tctggccgta tgcctggagg ccgattccct
    17341 cccggagctg atccatgtcg tcgatatgag ccatccactt gttgtcaatt accttcagaa
    17401 gaaccacgcg ctccagctca cggatctgct ctgcctgcgg gaactcagct tccttcgcct
    17461 cgtagagctt ggtcgcggac tccttcagca tatgctttaa ctcattcttc ttcatcttct
    17521 tctgatccgc attcagagtg atcggaggaa gcgggatgat ggagagaagc agggaattca
    17581 gctctgtcag attccactcc tcaggcgtct gctcgtcgga gatggacaga tccactgcat
    17641 tttccacaat atccgtgatc atcttcataa tcacgtttct catgttctcg ccgtccagaa
    17701 cgcggcggcg ctcctcgtag ataacctcgc gctgctcgtt cataacctcg tcgtatttta
    17761 acaggttctc acggattccg tagttgtttg tctcgatctt catctgagca ttctcgatag
    17821 ccttggaaag catcttgtgc tcaatctgct cgttctccgg cacgcccagc gcgttaaaca
    17881 tgcccatcag cttctcagaa ccgaagaggc gcatcagatc gtcctccaga gaaatgtaga
    17941 agcgtgactc gcccgggtct ccctgacgtc cagcacgtcc gcgcagctgg ttgtcaatac
    18001 gtctggactc gtggcgctct gtaccgatga tcttcagtcc gccgagagcc ttggactcgt
    18061 cgtccagctt aatatccgta ccacggccag ccatgttggt ggcgatggta acggcgccgt
    18121 ggatacctgc gtccgctaca atctcagcct ccagctcgtg gaatttagcg ttcagaacct
    18181 tatgcggaat gcccctcttc ttcagcatct tgcttaaaag ctcagaggtc tcgatggtga
    18241 tcgttcccac cagaaccggc tgtcccttct cgtgggccgc gcatacctcc tccacaactg
    18301 cgtggaattt ctctttcttc gtcttgtaaa cggcgtcgtt cttatcaata cggagcacag
    18361 ggcggttggt cggaatcacg ataacgtcca tctggtagat atttctgaac tccttctcct
    18421 ccgtctgagc cgtaccggtc atgccggcct tcttagtgaa tttattgaag aagttctgga
    18481 aggtgatggt agccagcgtg cggctctctc tcttaacctc cacatgctcc ttcgcctcga
    18541 tggcctggtg cagtccgtcc gaatagcggc ggcccggcat aatacgtccc gtaaactcgt
    18601 cgacaatgag aatttcgttg tcctttacca catagtcctt gtcgcggaac atcagatagt
    18661 tggcccgcag agccatgatc atgttgtgct ggatctccag gttctccgga tctgccaggt
    18721 tctcgatatt gaaatacttc tctaccttct taacgccctc taacgtcagg ttgactacct
    18781 tgtccttctc attgacaaca aagtcgcccg tctcctcgat ctcctcgccc atgatggcgg
    18841 agagcttggt aaactctgcg gaagcctcgc cctgctccag ctgcttggct aaaatgtcgc
    18901 agacctcgta gagctttgtg gactttccgc tctggcctga aataatcaga ggcgttctgg
    18961 cctcgtcgat taatacagag tccacctcgt caatgatggc gtaatccaga tttcttaaaa
    19021 ccatctgttc cttgtagatg gccatattat ctctcagata gtcaaagccc agctcgttgt
    19081 tcgtcacata ggtgatgtcg cagccatagg cggcctttct ctcctgagga gtcatggcat
    19141 ttaataccac gccgacggtc aggcccagga agcggtgcac ctcgcccatc cactcagcgt
    19201 ctcgctttgc caggtaatcg ttgaccgtaa cgataaatac gccttttccg gccagggcgt
    19261 tcaaatacgc cggacaggtg gaaacgagag tctttccctc accggtcttc atctctgcga
    19321 tacgtccctg gtgaaggaca ataccgccga tcagctgcac cggatagtgc tccatcttca
    19381 gcactcgctt cgccgcctcg cgaacagtgg caaaagcctc tggaagcaaa tcatccaaag
    19441 tctctccgtt tgccagacgc tccttaaact ttcttgtgtt gtcccgcagc tcctcgtctg
    19501 tcagcttctc catctccggc ttcaaagcta cgattttatc tacgatggga taaatcagct
    19561 ttaactctct gtcgctgtga gttccaaaca ctttctctat aagattcatg cttta
//
LOCUS       DBMDUW010000047        19112 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1737_length_19112_cov_4.119142, whole genome shotgun sequence.
ACCESSION   DBMDUW010000047 DBMDUW010000000
VERSION     DBMDUW010000047.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 19112)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 19112)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19112
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1737_length_19112_cov_4.119142"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..572
                     /locus_tag="ACZPCR_09060"
     CDS             <1..572
                     /locus_tag="ACZPCR_09060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HIR1231061.1"
                     /translation="AIKEFARVTIDKVSINQIIKNANISRGSFYTYFEDKWDVLAYIF
                     EDSRQKFVALMKLSLENNEGNLWMAFQDVMEAMLSFCSKRSNFEFLKNIMAHVNSDDM
                     LRGFSKKGGDYTRLPGCAEQWVYEHMDSKNLKTKSFEEFHCLFTLGMSSVGIAIREFY
                     EGTSKDEVRKLFAERIGLLKYGAFHGSGP"
     gene            636..1763
                     /locus_tag="ACZPCR_09065"
     CDS             636..1763
                     /locus_tag="ACZPCR_09065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007037668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1231062.1"
                     /translation="MKKKNMIITAAAVAVVAALVLPRFLKPKDSVNSAAAPVVSAEQP
                     QIGTIEIYTDLSGSIEPSEMASIIPKAGGEVTEVYVKAGDMVTEGQPICHIDTKMVDT
                     AKNSMETAAVNMENANKELERSRVLFESGNMSQQAFEQVQSSAKMAQLQYDSAKIAYD
                     NQVEFSSITAPISGKVESVSVEVHDNVGTQNIICVISGEGAKQVNFSVTERVVAGLHV
                     GDTVIISKNGTDYEGTISEVSTKIDDATGLFNVKASLAGADALATSSRVKLTVVSEKA
                     ENVLTIPTDAVYYSQNKPKVYTYDNGTVHEVPIETGIFDSEKTEVTSGLTTDDMVITT
                     WSSELYEGSQVQLPSEAASEGGEAQTGEQEEETTQTEQAAE"
     gene            1776..4829
                     /locus_tag="ACZPCR_09070"
     CDS             1776..4829
                     /locus_tag="ACZPCR_09070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0042908 - xenobiotic transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HIR1231063.1"
                     /translation="MGLTKFVLKRPVTTILSVICLIVFGLSSVLSSKLELIPEMDMPM
                     LIVATTYVGASPEDVSELVTKPIEDEIGTLNGVKSVNSYSQENISMVILEYQYGTDID
                     EAYDDLKKKMDLMGSTLPEDADDPAIVEMNINDMATMTLAVNDDTAENLYNYVDESIA
                     PEFEKISSVASVDVSGGQEQYIKVELIPEKLDQYHLSMSQVAQAVGSADFSLPAGSAI
                     VGSQKLSVSAGVSYDTMESLKTIPITVGSGDIIHLEDIANVHTNLEDPIGIGRYNGRD
                     TMTLAIKKQQESSAGEVSKAVNKTIERLERSNPNLDIVVVDDSSDSINASLKSVMETM
                     VMAVIISMIILWLFFGDIKASLIVGTSIPISILAALILMRAMGFSLNVITLGSLVLGV
                     GMMVDNSINVLESCFRAKEKLGNTATAFRDAALEGTRIMIASILGGTATTCVVFLPLA
                     LIQGLSGQMFKPLGFTIVFCMIASFVSAISIVPLCYVMYRPAEREKAPLSGVVKVMQD
                     QYRALIRFLLPKKKTVMFTSVLLLIFSFFLAGHIKMELMPASDEGTVQVTMELRPGIT
                     IEKVDQLVRDAEAYVAADEDVEDYILSYGASGLSISGGGSATLTAYLKDDRKRSTDQV
                     VRDWKPVLTAYPEMNVTVESSGSSSMMMSSTDGVEYLLKGTQYDELKNISDQIVNDLK
                     ERPELTKIHSSLENSAPVIQIDIDPVKASAEGMVPAQVAQTVYMMISGNEAAELEQNG
                     EEISIKIEYPDGWYETVDQVKGITVTGSNGNSIALADIADIYFKDSPQSITRKDKEYQ
                     VTITGDFVNGTNEDEMDALETKIYNETVAPRLTENVTRAQSSQDESMAEEFASLGGAI
                     GMSIFLIFVVMAAQFESPKFSVMVMTTIPFSLIGSFGLLFLADASISMASLLGFLMLF
                     GTVVNSGILYVDTANQYRAEMDRDTALVEAGATRLRPILMTTLTTVVSMIPMALAYGD
                     SGETMQGLALVNVGGLIASTILSLLMLPIYYTLMNRKPKQELDID"
     gene            4877..6034
                     /locus_tag="ACZPCR_09075"
     CDS             4877..6034
                     /locus_tag="ACZPCR_09075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008396606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1231064.1"
                     /translation="MKRKQTAAAAAAVLLALSSPLLVLAGPSGADGGVNEAYLAELND
                     GTLQYSELPGLVERYNVTYKNTYAQIAGQSQSLEAARQLGKDADEAMESALDLKEDDM
                     DESTRALYESYKEAAKAMRKQAAKLSDEDLSGTAERSLKMLKNQQTMLAQNLMIQYQK
                     AASKKDLLAKQEELAKAGYDAAAARAGLGMASSEEVLSANQSWLQAQSAAVQMDSAVN
                     SLKQNLLITCGWNADSDPEIAPLPEVDTARLDSMNLAADTETAAQANYNLISMRQNGA
                     SGSVERNALKRNVSQSRQSIAVNMEGLYAKTVAARQAYEGAEANFQAASLDMQAADQK
                     NAMGMMSKIDYLSAQAAYLTAKSERDDAKADLFSSIQNYDWALKGMTVSQS"
     gene            6050..7333
                     /locus_tag="ACZPCR_09080"
     CDS             6050..7333
                     /locus_tag="ACZPCR_09080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1231065.1"
                     /translation="MKRQYRQVLPLLTAAALASFSPMQALAENPQFAHDEATWARLQD
                     NTMEYDELSLLVEEYNPNYQNEQASYNDTKNDDDAAEIRKDAKNSADDMYDSAEDLRD
                     QAEDLSDQADDLSDQAEAAREAGNVALAAQLQAGAASYMAGYAPLMSAAAMTQNSALK
                     SDISADSSYVDSDMRKIQHIKNQKGIVVSTQNLFNSYNQLRVNADLIQKNVEVMEAAA
                     NAVQTQASIGMATQADVLKAQKNLQSIKSTQTETLSSLETLRQNLCMMTGWSYNAQPE
                     IKEVPQADLAAIDQINLEADRQKALENNYDLQYSRRALNNMQENSTDKKNQERTVKNL
                     EQSISASMTNLYNDIQQKKIAWQLAQAELATEQQSMSATETKRGLGMVSDLEYLQAQS
                     SFLGKQIAEKTANMALFQAVETYNWAVNGYLNQTQ"
     gene            complement(7459..7926)
                     /gene="ribH"
                     /locus_tag="ACZPCR_09085"
     CDS             complement(7459..7926)
                     /gene="ribH"
                     /locus_tag="ACZPCR_09085"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002593602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HIR1231066.1"
                     /translation="MKTFEGKLVSKEIKIGIVAARFNEFITAKLLEGAMDGLLRHNMD
                     EKDIHVAWVPGAFEIPLIASKMAKSRKYDAVICLGAVIRGSTSHYDYVCSEVSKGIAS
                     VSLESGVPVMFGVLTTENIEQAIERAGTKAGNKGFDCAVGAIEMVNLIREMEE"
     gene            complement(7947..9146)
                     /locus_tag="ACZPCR_09090"
     CDS             complement(7947..9146)
                     /locus_tag="ACZPCR_09090"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008704014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HIR1231067.1"
                     /translation="MTAFHSIEEALEDLRKGKIILVTDDAERENEGDFICAAQFASTA
                     NINFMATYGKGLICMPMSEEYVKKLKIPQMVEKNTDNHETAFTVSIDHITTSTGISAA
                     ERSVTALACVEENAKPEDFRRPGHMFPLLAKKNGVLERNGHTEAAVDLCRLAGLKECG
                     LCCEIMREDGTMMRSAELLELAKRFRIKYVTIQDLQNYRKCHDKLVKRMTTVKMPTKY
                     GNFTAYGFINTLNGEHHVALVKGDIGNGENVLCRVHSECLTGDTFGSLRCDCGQQFAA
                     AMTQIEKEGRGILLYMRQEGRGIGLINKLRAYELQEQGMDTLEANLALGFSGDEREYY
                     IGAQILKDLGVTSIRLLTNNPDKIYQLSDFGLEIKERIPLQMDATAHDLFYLKTKQKR
                     MGHILKY"
     gene            complement(9158..9805)
                     /locus_tag="ACZPCR_09095"
     CDS             complement(9158..9805)
                     /locus_tag="ACZPCR_09095"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HIR1231068.1"
                     /translation="MFTGIVEEIGTVNKIKRGQHSAVLEIGAKTILEDVKAGDSIAVN
                     GICLTVTALHSGAFTADVMHETLNRSALTSIVLGSHVNLERAMKANGRFGGHMVSGHI
                     DGTGKIIGIQKDDTAIWFTIQTKPEILNYIVEKGSIAIDGISLTAAKIEKDSFSVSAI
                     PHTVKQTILHERKEGSFVNLEADVIGKYIEKLLSISLKQQTSSLITKDFLTKYGF"
     gene            complement(9786..10892)
                     /gene="ribD"
                     /locus_tag="ACZPCR_09100"
     CDS             complement(9786..10892)
                     /gene="ribD"
                     /locus_tag="ACZPCR_09100"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009295914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HIR1231069.1"
                     /translation="MNDSDYMKVALELAEKGCGFTSPNPMVGAVIVKNGRIIGQGWHE
                     KYGEAHAERKALETCTENPKGATMYVTLEPCCHYGKQPPCVNAIIESGIERVVTGSSD
                     PNPLVSGKGIQILREHGIAVTEHILQEDCNQLNEVFFHYIHTKRPFVVMKYAMTMDGK
                     IAVHTGLSKWVTGETARSHVAQARSKYTAIMVGVGTVLADNPLLTCRIEGGKNPIRII
                     CDTTLCTPLTSNVVSTAKQFPTILATCCLIKERHRIYEEKGCYIVTVQKNNGHVDLVQ
                     LMDLLGQKQIDSILLEGGGTLNWSALSCGIVQKVQAYIAPKLFGGKTSKTPIEGEGVS
                     SPTEAFCLKNSRCLRLGDDFLIESEVEQIVHRDC"
     regulatory      complement(11048..11162)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(11399..12169)
                     /gene="spoIIR"
                     /locus_tag="ACZPCR_09105"
     CDS             complement(11399..12169)
                     /gene="spoIIR"
                     /locus_tag="ACZPCR_09105"
                     /inference="COORDINATES: protein motif:HMM:TIGR02837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HIR1231070.1"
                     /translation="MKFFCSLKETHSRCSFRGQLFLALSASCLALAVTCFIAWTRAEE
                     EQVAAALAPEVLRFHVLADSNSPDDQALKLQVRDLLLKEIRQGISGCSGKAQIQSYIT
                     ANETKLEQTANELIKDQGFSCTADIRLEKAYFPTRVYGNLTFPCGIYDSVRVVLGSGS
                     GHNWWCVLYPSLCFTSESFAVMPPESETELSGLLDEGIFEELHRERNLVFGESLGRSL
                     TKSQDSSQNKKASSSQAENPENHVKIVPDFYFLRWIRD"
     gene            12309..13370
                     /locus_tag="ACZPCR_09110"
     CDS             12309..13370
                     /locus_tag="ACZPCR_09110"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase family protein"
                     /protein_id="HIR1231071.1"
                     /translation="MKTKVLVLFGGQSSEHIVSCMSAVNVINHIDRSRYEVLIIGITE
                     EGKWLYTEDAAAIQDESWRQGTVQAVLSPDATEQCVLLLKEGGVEKRKVDVVFPVLHG
                     LYGEDGTVQGLFELARLPYVGCGVLASAVSMDKLYTKIIVDDLGVRQADYVPVMRREL
                     SCMETVVKRVEEKFSYPVFIKPSNAGSSRGVSKASCREELEKGLTEAARHDRKILVEE
                     MIVGHEIECAVFGGGNGEVIASGVGEILAAADFYDFEAKYYNEESRTVVNPPLPGGAA
                     EKVREAAKRIFRAVDGYGLSRVDFFVTEEGEAVFNEINTLPGFTAISMYPMLFEAEGI
                     EKTELITRLIENGLARYEA"
     gene            13402..14214
                     /gene="murI"
                     /locus_tag="ACZPCR_09115"
     CDS             13402..14214
                     /gene="murI"
                     /locus_tag="ACZPCR_09115"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HIR1231072.1"
                     /translation="MDRNAPIGVFDSGVGGLTVAREIMRQMPMERLVYFGDTARVPYG
                     TKSQDTVIRYSRQIIRFLRTKEVKAIVIACNTATACALETVEKDLDIPIIGVIHAGAK
                     AAVEATKNGKIGIIGTEATIRSGVYTELMKQMNPDIEVTGKPCPLFVPLVEEGLLHDS
                     VTDEIAGRYLAALKEKYIDTLVMGCTHYPLLRSTLGRLMGEDVTLINPAYETAMELRG
                     LLKEKGLDCSETGEGEKYQFYVSDMAERFKDFATAILPGEVKETKKINIEEY"
     gene            14306..14761
                     /locus_tag="ACZPCR_09120"
     CDS             14306..14761
                     /locus_tag="ACZPCR_09120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003497498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwiB family protein"
                     /protein_id="HIR1231073.1"
                     /translation="MTKDVLVSVRGIHTAEADGENGNVEVITAGTYYYKNNKHYVIYD
                     ELVEGYDKAIRSTIRIGDGTVDVIKNGPAKAHMVFEENKTNVSCYATPFGQMMVGVST
                     NTIEIEEKPDRIAVAVDYTLDVNYEKMSSCRISIDIQSKEKADFHLTSS"
     gene            14801..15394
                     /locus_tag="ACZPCR_09125"
     CDS             14801..15394
                     /locus_tag="ACZPCR_09125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006776806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HIR1231074.1"
                     /translation="MIKKQREAAIKPGIYEIAVNGLFTALIAVGAFIKISIPVQPFPM
                     NFTLQFFFVLLAGLLLGGKQAFFCVLTYLAVGLAGVPVFAAGGGPAYLLRPTFGFLLG
                     FAAAAWVTGTVYSRFKDRGFKMRRLFAASLCGFAVMYLCGMFYFYFLSNYVIHMPVSA
                     GVVFVNCFLLTAAGDLFLCFLASMAAKRLGPAMSFMR"
     gene            complement(15423..15782)
                     /locus_tag="ACZPCR_09130"
     CDS             complement(15423..15782)
                     /locus_tag="ACZPCR_09130"
                     /inference="COORDINATES: protein motif:HMM:NF024252.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1231075.1"
                     /translation="MLKFADKLKLIRKANNMTQAAFASSIGISRGNLANLECENVKPT
                     PMFINCLSLMYHVDKNWLLDDSNDDLSALNGTTNILSLIMDKYELLDDKHKKFVENQI
                     NELLKLQNMDSEKDVLK"
     gene            15965..16150
                     /locus_tag="ACZPCR_09135"
     CDS             15965..16150
                     /locus_tag="ACZPCR_09135"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231076.1"
                     /translation="MDRSGNTKVKNASEIGALAGRLNVHNQFYVLNTINFFLSGQNMQ
                     KTHRSKAAEEICLKEKR"
     gene            16155..16928
                     /locus_tag="ACZPCR_09140"
     CDS             16155..16928
                     /locus_tag="ACZPCR_09140"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231077.1"
                     /translation="MKKKSLKKIAVAALSLALMSPAAVFAGTWEKDGDNWKYKKDDGQ
                     YAEYEWVQDTDGTWYYCKRWGTMEMNHLIDGYYVGADGRMVSKDDTANPLNQADIYGT
                     CYMSVDRFQDQGDYYQAKVTLYDSSFGTGIDFWNYSKGDKFWIEAVGDYGKVKSVSLS
                     AYGDAYMEVSYGTETFVYDGEEVWCCGDGSETPVLRKVKENVDVKIPKNISVISAPGF
                     EQFTLSLDSYLNDSVYKMTPVFNGTTIEKLYDSFINYAG"
     gene            16964..17578
                     /locus_tag="ACZPCR_09145"
     CDS             16964..17578
                     /locus_tag="ACZPCR_09145"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231078.1"
                     /translation="MNSTMNENLRDLQDIRRQMDIYQPIGREYLRQVRFYRNYEKAVE
                     RWQPSHKIKNTALCALIMLLVGPLGLIAAAALWFGGHDKILEIKERQKGEQEKKIMDL
                     HGQFLEKYLPVQEKCERLLLGQEDYEVPMAVDYLIYVISNERAETMKEAYNMLDEQLH
                     RWTMENMQREQLDLQREQCKQLRRIEVNTTISAASDLFHVINSL"
     gene            17605..17931
                     /locus_tag="ACZPCR_09150"
     CDS             17605..17931
                     /locus_tag="ACZPCR_09150"
                     /inference="COORDINATES: protein motif:HMM:NF017470.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HIR1231079.1"
                     /translation="MELLKDYISKAFDFSGEETGRNYKKMCLLSGVLYIILYYVWSII
                     QKIAIGRVLLSLFIPVCLGVVVLAFVAATFRRCGCTGRSKWWCAVCVLAGPLSFVILF
                     FVLGRD"
     gene            17936..18142
                     /locus_tag="ACZPCR_09155"
     CDS             17936..18142
                     /locus_tag="ACZPCR_09155"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231080.1"
                     /translation="MNIKKERCKTAGWKWPLRQRFFRRIQKLNLGGSRILYGYDTLNT
                     LADKKYEADNLGSVIYSDRKRVSL"
     gene            18234..18905
                     /locus_tag="ACZPCR_09160"
     CDS             18234..18905
                     /locus_tag="ACZPCR_09160"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231081.1"
                     /translation="MKRPDGTVSSYTYNARNQVLEAKNTCVCGFLISDYQYTYDGDGN
                     RVFQLNYNPDAECGYGKNVSGEIFMPEHSHNEDGSLTAEGELFGYICSATGRAYDLTE
                     YVNDTNREHTEVFTAFNINTGFDMESYTYAGSSRLSRNNIWNEARDVNHDEMSCCLYD
                     GQGSVTANTWYNGMVTDVYQYDPYGRMELGGEGHTDFYSCRAESYHNEDAEVIMEGYN
                     INIVG"
     gene            18932..>19112
                     /locus_tag="ACZPCR_09165"
     CDS             18932..>19112
                     /locus_tag="ACZPCR_09165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009534887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231082.1"
                     /translation="MLALNGYYDGTAIQALEKINAKKNQKLIITVLDEFIEEIPKKNS
                     TSARGSLAKYANTALW"
BASE COUNT         5374 a         4152 c         4803 g         4783 t
ORIGIN      
        1 cggcaattaa agaatttgcc agagtaacga ttgataaggt ttcaattaac cagattatta
       61 aaaacgccaa catttccaga ggcagttttt atacatattt tgaggacaaa tgggatgtgc
      121 tggcctatat ttttgaggac agccgccaga aatttgtggc tctgatgaaa ctttcattag
      181 agaataacga gggaaatctt tggatggctt ttcaggatgt gatggaggcg atgctttcat
      241 tttgctcaaa gaggtctaat tttgagttcc tgaagaatat tatggctcat gtcaattctg
      301 acgatatgct gagaggattt tccaagaagg gaggagatta tacaaggctt cctggctgcg
      361 cagagcagtg ggtatatgaa cacatggata gtaaaaattt aaagacaaag agctttgaag
      421 aattccattg tctgttcaca ttgggaatgt ccagcgtagg aatcgccatc cgggagtttt
      481 acgagggaac ctcgaaggat gaagttagga agttatttgc agagagaatc gggcttctga
      541 aatacggagc cttccatggc agcggcccct agagagaagc tggcataaac atggcatata
      601 atgaagacag aaagtaagta agggagaaga acaacatgaa gaaaaaaaac atgatcatca
      661 cagctgccgc tgtagctgta gtagcggctc ttgttctgcc gcgtttcctg aagccaaagg
      721 attcggttaa ttcagcagca gctcctgtcg tttcagcaga gcagccgcag ataggaacca
      781 ttgagattta tacagacctg tcaggaagca ttgagccgtc ggagatggct tctattattc
      841 cgaaggccgg aggagaggtc acagaggtct atgtaaaggc cggcgacatg gtcacagagg
      901 gacagcctat ctgccatatt gacactaaga tggtagacac agctaagaac agcatggaga
      961 cagccgctgt caacatggag aacgccaata aggagctgga acgatccaga gttctctttg
     1021 agagcggaaa tatgtcccag caggcttttg agcaggttca gagcagcgcc aagatggctc
     1081 agctgcagta tgactccgct aagattgcct atgacaacca ggtagagttc agctccatca
     1141 cagcgccgat ttccggcaag gtggagagcg tcagcgtgga ggtccacgac aacgtaggca
     1201 cccagaacat tatctgcgtg atttccggag agggcgcaaa gcaggtaaac ttctctgtaa
     1261 cagagcgcgt ggttgctgga cttcatgtgg gcgacacagt gattatcagc aagaacggaa
     1321 ccgattacga gggaacgatt tccgaggtca gcacaaagat tgacgacgcc accggcctgt
     1381 ttaacgtaaa ggcttccctg gcaggtgcag acgcgctggc caccagctcc agagtaaagc
     1441 ttacggttgt gtctgagaag gcagaaaacg tgctcacgat tccgacggac gcagtttact
     1501 actctcagaa taagccgaag gtttacacct acgacaacgg aacggttcac gaggttccga
     1561 ttgagactgg aatttttgac tcagagaaaa cagaggtaac atccggtctt acaacagacg
     1621 atatggttat cacgacatgg agctcagagc tttatgaagg ctctcaggtg cagcttcctt
     1681 ctgaggccgc ttctgaaggc ggagaggctc agacaggaga gcaggaagaa gagactaccc
     1741 agacagagca ggcagcagag taaggaggcg tacatatggg tttaactaaa tttgtcctga
     1801 agcgtcctgt cactacgatc ctgtcagtta tctgtctgat cgtattcggt ttatcctccg
     1861 ttctttcctc caagctggag ctgattccgg agatggatat gcccatgctg attgtggcca
     1921 ccacatatgt gggagccagc ccggaggacg tcagcgaact ggtaacgaag ccgatagagg
     1981 atgagatagg aaccttgaac ggcgtaaaat ccgtcaacag ctactcccag gagaatatct
     2041 ccatggttat tctggagtat cagtacggaa cagatattga cgaggcttat gacgatttaa
     2101 agaaaaagat ggatttgatg ggatccactc tgccggagga tgcagacgat ccggccattg
     2161 tggagatgaa tatcaacgat atggctacca tgactctggc ggtcaacgat gatacagcgg
     2221 aaaaccttta taattacgtg gacgagagca tcgctcctga atttgagaag atttcttccg
     2281 ttgccagtgt agacgtcagc ggaggacagg agcagtatat caaggttgag ctgattccag
     2341 agaagcttga ccagtaccat ttatccatga gccaggtggc tcaggcagtg ggaagcgcag
     2401 acttctccct tccggccgga agcgcgattg taggaagcca gaaattatcc gtatcggcag
     2461 gcgtcagcta cgatacgatg gagagcttaa aaacgattcc gattactgtg ggaagcggcg
     2521 atatcatcca cctggaggac attgccaatg ttcatacaaa tctggaggat ccgattggta
     2581 tcggacgcta taacggcaga gacaccatga cgctggctat caagaagcag caggaatcct
     2641 cagccggaga ggtatcaaag gcagtaaata agacaattga gcgtctggaa cgaagtaatc
     2701 cgaacctgga tatcgttgta gttgatgaca gcagcgacag cattaacgcc tctttaaaga
     2761 gcgtaatgga gaccatggtc atggcggtta tcatttccat gattatcctg tggctgttct
     2821 tcggagacat taaggcgtct ctgattgtag gaacttccat tccgatttcc attctggcgg
     2881 cgctgattct gatgagggcc atgggcttct cactgaacgt tatcaccctg ggcagccttg
     2941 ttctgggcgt cggaatgatg gtcgacaact cgatcaacgt gctggagagc tgcttcagag
     3001 caaaagaaaa gcttggaaac acagcaaccg ccttcagaga cgcagccctg gagggaacaa
     3061 gaattatgat tgcctctatc ctgggcggta cggcgaccac ctgcgttgta ttccttcctc
     3121 tggctctgat tcagggtctg tcaggacaga tgttcaagcc ccttggattt acgattgtat
     3181 tctgtatgat cgcctccttt gtttccgcta tctctatcgt gccgctgtgc tacgtaatgt
     3241 accgtccggc agagagggag aaggctccgc tgtccggcgt ggtaaaggta atgcaggatc
     3301 agtaccgcgc actgattcgg ttcctgcttc caaagaagaa aaccgttatg ttcaccagcg
     3361 tgcttctgtt aattttctct ttcttcctgg caggccacat taaaatggag ctgatgcctg
     3421 catcggatga gggaacggtt caggtaacca tggagctgcg cccgggtatt acaatcgaga
     3481 aggttgacca gctggtaaga gacgctgagg catatgtggc ggcagatgaa gatgtggagg
     3541 attacatttt atcctacggc gccagcggcc tgagcatttc aggcggagga tccgctaccc
     3601 tgacagctta cctgaaggac gacaggaagc gttccacaga ccaggtggta agggactgga
     3661 aaccggttct caccgcctat ccagagatga atgtgacagt agaatcctca ggttccagct
     3721 ctatgatgat gagcagtaca gacggagtgg aataccttct gaaaggaacc cagtacgatg
     3781 agcttaaaaa tatttcggac cagattgtca acgacttaaa ggagagaccg gagctgacaa
     3841 agattcactc ctccctggag aactccgcgc ctgttattca gattgacatc gatccggtaa
     3901 aggcctctgc agagggcatg gtccccgctc aggtagccca gactgtatac atgatgatca
     3961 gcggaaatga ggctgccgag ctggagcaga acggcgagga aatcagcatt aagattgagt
     4021 atccggacgg ctggtatgag acggtagacc aggtaaaggg aattaccgta acaggctcta
     4081 acggcaactc catcgctctg gctgatattg cggacatcta cttcaaggac agcccgcaga
     4141 gcattacgag aaaggataag gagtatcagg taaccatcac aggcgatttt gtcaacggca
     4201 caaacgagga cgaaatggac gccctggaga cgaagattta caatgagaca gtcgctccaa
     4261 gactgacaga gaacgtaacg agagcacaga gctcccagga tgagagcatg gccgaggagt
     4321 tcgcttcctt aggcggcgcc atcggaatgt ccatcttctt aattttcgta gttatggcgg
     4381 ctcagttcga gtctccgaag ttctccgtca tggttatgac gaccattccg ttcagcctta
     4441 ttggttcctt cggacttctg ttcttagcag acgccagcat cagtatggcg tccctgttag
     4501 gattcctgat gctgttcgga accgttgtaa actccggtat cctttacgtg gatacagcta
     4561 accagtacag ggcggaaatg gatcgcgaca cagctctcgt agaggcaggc gcgacgcgtc
     4621 tgcgcccaat ccttatgaca acgctgacaa ccgtagtatc catgattcct atggctctgg
     4681 cctacggaga cagtggagag accatgcagg gcctggccct tgtaaacgtg ggaggcctca
     4741 ttgcctctac gatcctgtcc ctgttaatgc ttcctattta ctatactctg atgaacagga
     4801 agccgaagca ggagctggac atcgactgat aaacaagctg attacacatc atagaacacc
     4861 tggaggtgac agaaccatga aacgaaaaca gacagccgcc gcggcagcgg ccgttctcct
     4921 ggctctctcc tcccccctcc tggtcctggc agggccgtcg ggggcggacg gaggagtcaa
     4981 tgaggcgtat ctggccgagc ttaacgacgg gactctccag tacagcgagc tgcccggatt
     5041 agtggagcgg tataatgtaa cctataaaaa tacatatgcg cagattgccg gacagagcca
     5101 gagtctggaa gcagccagac agctgggaaa ggacgccgac gaagcgatgg aaagcgcgct
     5161 ggatctgaaa gaggacgata tggacgaatc caccagagcg ctctatgaat cttataagga
     5221 ggccgccaag gccatgagaa agcaggcagc caaactgtcc gatgaagacc tgtcaggtac
     5281 agcggagcgt tcgctgaaaa tgctgaagaa ccagcagacc atgctggccc agaacctgat
     5341 gattcagtac cagaaggcgg cttccaagaa agatctgtta gccaagcagg aggagttagc
     5401 caaagccggc tacgacgcgg ctgcggccag agccggcctt ggaatggcct cctctgagga
     5461 ggtgctttct gcgaaccaga gctggctcca ggctcagagc gcggcggttc agatggactc
     5521 tgcagtcaac agcctgaaac agaacctgct gattacctgc ggctggaatg ctgacagcga
     5581 tccggagatt gcgccgctcc ctgaggtgga tacggcaagg ctcgacagca tgaatctggc
     5641 ggctgataca gagacggccg ctcaggctaa ctataacctg atcagcatgc gccagaacgg
     5701 agccagcggt tcagtggaaa gaaatgccct gaagaggaac gtatcccagt cccgccagag
     5761 cattgcagtc aatatggaag gcctttatgc aaagacagtg gcggcccgcc aggcttacga
     5821 gggggctgag gccaatttcc aggccgcttc cctggatatg caggccgcag atcagaagaa
     5881 tgctatgggg atgatgagca aaattgatta tctgagtgct caggccgctt atttaactgc
     5941 caagtccgag agggacgatg ccaaggcaga tttattttcc agcatacaga attatgattg
     6001 ggcgttaaag ggaatgacag tttcacagag ttaaaatgga gggaaaaaca tgaaaagaca
     6061 gtatagacag gttttaccgc ttctgacagc agcagccctc gcctcttttt ctcctatgca
     6121 ggcgctggcc gaaaaccccc agtttgccca cgatgaggct acctgggcaa gacttcagga
     6181 caataccatg gagtacgatg agttgagtct tctggtggag gagtataacc ctaactacca
     6241 gaatgaacag gcgtcctaca atgatacaaa gaatgacgat gatgcagctg agatccgtaa
     6301 ggatgcgaaa aacagcgctg acgacatgta cgactctgcg gaggatctga gagatcaggc
     6361 agaggattta agtgaccagg ccgatgattt gagcgatcag gctgaggcgg ccagagaggc
     6421 tggaaatgtg gctttggcag cccagctcca ggcaggggca gccagctata tggccggcta
     6481 tgcgccttta atgtcagcgg cggccatgac gcagaacagt gccttaaagt ctgatatctc
     6541 tgcagacagc tcctatgtag acagcgatat gcgcaagatt cagcacatta aaaatcagaa
     6601 gggcattgta gtgtccaccc agaatctgtt caattcctat aatcagctgc gggtgaacgc
     6661 agatctgatt cagaaaaatg tggaggtcat ggaggcggcg gcaaacgctg tgcagactca
     6721 ggcttccatt ggaatggcta cccaggcaga cgttttaaag gcccagaaga atctgcagtc
     6781 tattaaatca actcagacag agactctgtc aagccttgag actctgcggc agaacctgtg
     6841 tatgatgaca ggctggagct acaacgcaca gccggaaatc aaggaagttc cgcaggcaga
     6901 tctggcggct attgaccaga ttaatctgga agccgaccgt cagaaggccc tggagaacaa
     6961 ttatgatctt cagtacagca ggagagcgct gaacaacatg caggaaaact ctacagataa
     7021 gaagaatcag gaaagaactg taaaaaatct ggagcagagc atcagcgctt ccatgacaaa
     7081 tctgtataat gatattcagc agaaaaagat tgcatggcag ttagctcagg ctgagctggc
     7141 tacagagcag cagtcaatgt cagctacaga gacaaaacga ggcctgggaa tggtcagcga
     7201 cctggagtat ctccaggctc agtcatcctt cctgggaaag cagattgcag agaaaactgc
     7261 aaatatggct ctgttccagg ctgtggagac ctacaactgg gcagtgaacg gatatctgaa
     7321 tcagacacag taataagagg aagaattgag aggaagaaaa gaggttttcc agctccacca
     7381 aaggcttagc cgcaggaaaa cctctttctt cctcttttct ttcaactcgt tctggctggc
     7441 tttgctataa aaagttattt attcttccat ttcccgaata agatttacca tttcgattgc
     7501 tcctacagca caatcgaacc ctttatttcc agcctttgta cctgcccgct caattgcctg
     7561 ctcgatattt tctgttgtga gaacgccaaa catcactggc acgccactct ccaaagaaac
     7621 agaagcaatc ccttttgaaa cttcgctgca tacataatca taatggctgg ttgaaccacg
     7681 aatgactgct cccagacaaa ttactgcatc gtattttctg ctttttgcca ttttagacgc
     7741 aataagcggg atttcaaaag caccaggaac ccacgccaca tgaatatcct tttcatccat
     7801 attatggcgg agcagaccat ccattgcgcc ctctaagagt ttagcagtga taaattcgtt
     7861 aaaccttgcc gcaacaatcc cgattttgat ttcttttgat accagttttc cctcaaatgt
     7921 tttcatattg caaatcctcc tgtaatttag tattttaaga tatgtcccat gcgtttttgc
     7981 ttggttttaa gataaaataa gtcatgcgca gtagcatcca tttgaagtgg tatccgctct
     8041 ttaatttcca gtccaaagtc tgaaagctgg taaattttgt ccggattgtt tgttaaaagc
     8101 cgtatactgg tcacgcccaa atccttcaaa atctgtgcgc ctatataata ttcccgctca
     8161 tctccggaaa agcccaacgc aaggttagct tccagtgtgt ccatgccctg ttcctgcaat
     8221 tcataagcac gcagtttatt gattagtccg ataccacgtc cctcctgccg catataaagc
     8281 aagataccac gtccctcctt ttcaatttgc gtcatggcag ctgcaaattg ctgtccacag
     8341 tcacagcgca gagaaccaaa ggtatctccg gttaaacact cagaatggac gcggcacaga
     8401 acattttcac catttcctat atctcctttt acaagcgcaa cgtgatgttc tccattcagc
     8461 gtatttataa atccataagc ggtaaaattc ccgtattttg tcggcatttt tacagttgtc
     8521 atccgcttaa ctaatttatc atggcatttg cggtaattct gcaagtcctg tattgtcaca
     8581 tatttaattc taaagcgctt cgcaagctct aaaagctctg cgcttctcat catagttcca
     8641 tcctcccgca taatttcaca acacagtcca cattctttta agcctgctaa cctgcataaa
     8701 tctacggctg cttctgtatg accatttctt tctaatacgc catttttctt tgcaagtaac
     8761 gggaacatat gtcccggtct gcgaaaatcc tctggctttg cattttcctc cacacaggcg
     8821 agagcagtaa cagagcgttc agcagcagaa atcccggtag aagttgttat atgatcgatt
     8881 gataccgtaa atgccgtttc gtggttatct gtatttttct ctaccatttg agggatttta
     8941 agttttttca catattcttc tgacatgggc atacaaatca gccctttacc ataggttgcc
     9001 ataaagttta tatttgccgt tgaagcaaac tgtgcggcac atataaagtc cccttcgttt
     9061 tctcgttctg catcatcagt tactaaaatg attttccctt ttctcaaatc ttcaagtgct
     9121 tcttcgattg aatgaaatgc tgtcatatgc catcctccta aaatccatac tttgttaaaa
     9181 aatcttttgt aataagactg cttgtttgct gttttaaaga tatggataat aatttttcta
     9241 tatatttgcc aataacgtcc gcttccagat tgacaaagct tccctctttt cgttcatgca
     9301 gaatggtttg tttaactgta tgtggaatgg cagaaacaga aaaactgtcc ttttcaattt
     9361 tggcagctgt caggctgatt ccgtcgattg caatagaacc tttttctaca atataattca
     9421 ggatttccgg ctttgtctgt atagtaaacc aaattgccgt atcgtctttc tgtatgccaa
     9481 tgattttccc tgtgccgtct atatgcccgg aaaccatatg ccctccaaat cttccgtttg
     9541 ctttcatggc acgctctaaa tttacatgac tgccgagaac tatacttgtc aaagcagagc
     9601 ggtttaaagt ttcatgcata acatctgccg taaatgcacc agaatgcaga gctgtaacgg
     9661 ttagacaaat tccgttgact gcaatactgt cccctgcttt tacgtcctcc agaatcgtct
     9721 tcgcgccgat ttccaaaaca gcagaatgct gtccccgttt gattttattc actgttccga
     9781 tttcttcaac aatcccggtg aacaatttgc tccacctcgc tttcaattag aaaatcatcg
     9841 cctaaacgca gacaacggct gttttttaaa caaaatgcct cggtaggaga gctgacaccc
     9901 tctccctcaa tgggagtttt tgatgtttta ccgccaaaca gcttcggcgc aatataagct
     9961 tgtactttct gaacaatacc acaggaaagg gccgaccagt tcaatgttcc tcccccctct
    10021 aacaaaatac tgtcaatctg tttctgccct aacaagtcca tgagctgtac caaatctaca
    10081 tgaccattat ttttttgaac tgtcacaata tagcagcctt tttcttcata gattctgtga
    10141 cgttctttta tcagacaaca agttgcaagt atggtaggaa actgttttgc tgtggaaacc
    10201 acgtttgatg taagcggtgt gcaaagagtg gtatcacaga taatacgaat tggatttttt
    10261 cctccctcta tccggcaagt caataatgga ttatctgcta atacagttcc tacgcctacc
    10321 atgattgcag tatatttgct gcgtgcctgt gccacatggc tgcgtgccgt ttctcctgtc
    10381 acccattttg ataatcccgt atgtactgcg atttttccgt ccattgtcat agcgtatttc
    10441 atcacgacaa aaggacgctt ggtatgaata taatggaaaa atacttcatt tagctggtta
    10501 caatcttcct gcaaaatatg ttctgtcact gcaattccat gctcccgcaa aatttgtatg
    10561 cctttaccgc tgacaagagg atttgggtca ctggaacctg ttacaacccg ctcaatgcca
    10621 gattctataa ttgcattgac acaaggcggc tgctttccat aatggcagca aggttctaag
    10681 gttacataca tagttgcacc ttttggattt tctgtgcagg tttctaaagc cttgcgctct
    10741 gcatgagctt ctccatattt ttcatgccag ccttgcccaa taattcgccc attttttaca
    10801 atgacagccc caaccatagg gttcggtgaa gtaaatccac atcccttttc agcaagctcc
    10861 aaagcaacct tcatataatc gctgtcattc atatcatcac ctcctcaaat aaaaaatgcc
    10921 ttgaacaaaa ccgttcaagg catacagaac aacgcagagt aaaatactgt gtaaaaataa
    10981 agctctggag taaatacaca ccagagcaaa tatatactac acagaaagaa acacttcccc
    11041 ctgcattcat tatcttcttt catccagact gtactgtcgg cttcggagtt tcaccgaatc
    11101 atgccttacg gctcgtgggc tttaccaccg gtagggaatt gtaccctgcc ctgaagattt
    11161 tatttaattt ttaaaataag tataaccatc tgttttgcag ttgtcaagaa atttattttc
    11221 gcagcagcgg tttggttatt atttcaattt tttgttactt tacctcacat aagtattctg
    11281 ctatagagtg aagcgtctga atatcaggcg agttttcgcc tgcatttgtg agaagataaa
    11341 gattctgcag agaagatttc tggtggtttt cagtggaaca agaaaatctt cctttcttct
    11401 agtctcttat ccatcttaaa aagtagaaat ctggaacgat ttttacatgg ttttctggat
    11461 tctccgcctg gctggaggaa gcttttttat tctgagagct gtcttgggat ttggtaagag
    11521 accgtcccag agattcacca aagaccaggt ttcgctccct gtgaagctct tcaaatatgc
    11581 cctcgtccaa cagaccggac agttctgtct ctgactcggg aggcatgacg gcgaaggact
    11641 cagaggtaaa gcacagagaa gggtagagga cgcaccacca gttatggccg ctgccgcttc
    11701 ccaggacaac ccggacagag tcatagatac cgcagggaaa agtcaggttt ccgtagacgc
    11761 gggtaggaaa atatgccttt tccaggcgga tgtccgcagt acaggaaaag ccctggtctt
    11821 ttatcaattc gttggcagtt tgttccagct ttgtctcgtt ggccgttatg taggactgaa
    11881 tttgtgcttt tccagaacag ccagagattc cctggcggat ttctttcaaa agcagatccc
    11941 gcacctggag ttttagagcc tgatcgtcag gagaattgct gtcagccagc acatgaaagc
    12001 gcagcacctc aggagccaga gccgctgcca cctgttcttc ttctgctctg gtccaggcga
    12061 tgaaacaggt gacagccaga gccagacagg atgcagacag ggcgaggaaa agctgtcctc
    12121 tgaaagaaca gcgggaatgg gtttctttta aagaacaaaa aaatttcatg attacctccc
    12181 aaaatgtttg gcagctgctg ttttgatgtt ctaagtattg acaggcgtga tataatttaa
    12241 acagtttcca cagaagaaat attttgaaaa ttgtcaatta agaaagtatc agaaaagagg
    12301 aaaaatagat gaagacaaag gtgctcgttc tattcggcgg ccaatcctca gaacacattg
    12361 tgtcctgcat gtcagccgtc aatgtaatta accacataga cagaagcaga tatgaagtgc
    12421 tgattatcgg cattacagaa gagggaaaat ggctttatac agaggatgca gcagcgattc
    12481 aggatgaaag ctggcggcag ggaacagtgc aggctgtgct ttctccagat gctacagagc
    12541 agtgcgtgct ccttttaaaa gaaggaggag tggagaaaag aaaggtggat gtggtgttcc
    12601 cggtgctcca tggactgtat ggagaggacg gaactgtgca gggtctcttc gagctggcgc
    12661 ggctccccta tgtgggctgc ggtgttctgg cgtctgctgt ttccatggat aaattatata
    12721 caaaaatcat tgtagatgac ctgggagtcc gtcaggcaga ctatgtacct gtgatgcgcc
    12781 gggagctgtc ctgcatggaa acggtagtaa aacgggtgga ggaaaaattc tcctatcctg
    12841 tatttatcaa gccgtccaat gccggatcat ccagaggcgt gtccaaggct tcctgcaggg
    12901 aagagcttga gaaaggcctg acagaagcag ccagacacga tcgaaagatt ctggtagagg
    12961 agatgattgt gggccatgaa attgagtgcg ctgtgttcgg cgggggaaat ggagaggtca
    13021 ttgcctccgg tgtaggcgag attctggccg ctgcagattt ctatgatttt gaagcaaaat
    13081 attataatga agaatccaga acagtggtta atccacctct gccaggcggg gctgccgaga
    13141 aagtcaggga ggcggcaaag cggattttcc gggcagtgga cggctatggg ctttccagag
    13201 tagatttttt tgtgacagaa gaaggcgaag cagtatttaa cgagatcaat actcttccag
    13261 gctttactgc tatcagtatg tatcccatgc tgtttgaggc agagggcatt gaaaagacag
    13321 aattgattac acgcctgatt gaaaacggcc tggcccggta tgaggcctag agggcagcag
    13381 cccttcaggg aggagaaaga gatggataga aatgcgccga taggagtctt tgattctgga
    13441 gtaggaggac ttacagtagc cagagaaatt atgcgtcaga tgcctatgga acggctggta
    13501 tacttcggag acacagcgag agttccctat ggaacgaaat cccaggatac ggttatccga
    13561 tattccaggc agattatccg atttctgcgg accaaagagg tcaaggccat tgtcattgcc
    13621 tgcaacacag ctacagcctg cgctcttgag actgtagaga aggacttgga tatcccgatt
    13681 atcggcgtga tccatgcagg ggctaaggcg gctgtggaag cgacaaaaaa cggaaaaatt
    13741 ggaattattg gaacagaagc tacaatcaga agcggcgtgt acacggaact gatgaaacag
    13801 atgaatcccg atattgaggt gacgggaaag ccgtgccctt tgtttgtccc cctggtggaa
    13861 gagggacttc tccatgactc tgtcacagac gagatagcag ggcggtatct ggccgccctg
    13921 aaggagaaat acattgacac cttggtgatg ggctgtactc attaccctct gctccgctcc
    13981 acgcttggaa ggctgatggg agaggatgtg acccttatca atcctgccta cgaaacggcc
    14041 atggagttgc gcggcctgtt aaaggaaaaa ggcctggact gcagcgagac aggagaagga
    14101 gagaaatatc agttttacgt cagcgacatg gcagagcgct ttaaggattt cgccacagcc
    14161 atcctgccgg gagaggttaa ggaaacaaaa aaaattaaca ttgaagagta ttaaagacag
    14221 gctcagggca ggaatagaag agcataaaac aagagcagat acaaattaga aaaatgagtg
    14281 agagagaaac agaggagaca cagctatgac gaaagatgtt ctggtcagcg tccggggcat
    14341 tcatacagcg gaggcagatg gggagaacgg caatgtggag gtaatcacag ccggaaccta
    14401 ctactataaa aacaataagc attatgtcat ttatgacgaa ctggtggagg gatacgacaa
    14461 ggctatccgc agtacaatca gaattggaga cggaacggta gatgtaatta aaaacggacc
    14521 agccaaggcc cacatggtat ttgaggaaaa taagacgaat gtcagctgct acgctacgcc
    14581 tttcggccag atgatggtag gagtaagcac gaatacaatt gaaatagaag aaaaaccgga
    14641 tcggattgca gtggcagtgg actacacgct tgatgtcaac tatgaaaaaa tgtccagctg
    14701 caggatttct attgatatcc agtccaagga gaaagcagat tttcacctta cttccagtta
    14761 agcatttttt cagggctgca tgcggcagaa aggagtacct atgataaaaa aacagagaga
    14821 ggctgccata aaaccaggta tctatgaaat tgcggtgaac ggcctgttca ccgccctgat
    14881 cgcagtgggt gcgtttataa aaatcagcat tccagtacag cccttcccca tgaactttac
    14941 cctgcagttt tttttcgttc tgctggcagg gcttctgctg ggaggaaagc aggcgttttt
    15001 ctgcgttctg acatatttag cggtaggact ggcgggagtg ccggtattcg cagcaggggg
    15061 aggccctgct tatctgctgc gtcccacctt tgggttcctt ctgggatttg cagcggctgc
    15121 ctgggtgacg ggaaccgtct actcccgctt taaggacaga ggatttaaga tgaggcggct
    15181 gtttgcagcg tctctctgcg gttttgctgt catgtatctg tgcggtatgt tttattttta
    15241 ttttctcagc aattatgtga ttcacatgcc ggtttctgca ggggtagtat ttgtaaactg
    15301 ttttctgctg acagcagcag gagatttgtt cctgtgcttt ctggccagca tggctgcaaa
    15361 aaggctgggg ccagccatga gctttatgag gtaagaagag aagctcccct gggagcttct
    15421 ttttatttca gcacatcctt ttcactatcc atattttgta atttcagcag ttcattaatc
    15481 tgattttcta caaatttttt atgcttgtca tccaataatt catatttatc cataatcaga
    15541 gagaggatat tggtagtgcc gttcagggcg cttaaatcat cgttggaatc atccaagagc
    15601 cagtttttgt caacatggta cataagagac aggcaattga taaacatggg cgtaggcttt
    15661 acattctcac actccagatt tgccagattt cctctggaga taccgatgga agaggcaaaa
    15721 gctgcctgcg tcatattgtt tgcctttcgg attaatttta atttatctgc aaatttcaac
    15781 acaatctacc tccatagcct tatagtatca aagtgaaaag tttgtgtcaa tgcaaaatga
    15841 catggtacaa acattttgat aaataagaag cattgacgca aacatttaaa aatgatagaa
    15901 tgcacttaaa caaactattt ttgatgtttt ttgcaattat aatgacaaaa aagggggata
    15961 ttttatggat agatcgggaa acaccaaagt aaaaaacgca tctgagatag gtgcgcttgc
    16021 aggccgctta aatgtacata atcagtttta tgtgctgaat acgatcaatt tctttttatc
    16081 cggacaaaat atgcaaaaaa cacacagatc aaaggcagca gaagaaattt gtttgaaaga
    16141 aaagaggtag agaaatgaaa aagaaaagct taaagaaaat cgcagtggca gcgcttagcc
    16201 tggccttaat gagtccggct gccgtttttg caggaacctg ggaaaaggat ggcgataatt
    16261 ggaagtataa aaaggatgac ggacagtatg cagagtatga gtgggttcag gatacagacg
    16321 gaacctggta ttactgcaaa agatggggaa ccatggagat gaatcacttg attgacggct
    16381 attatgtggg agcagacgga aggatggttt caaaggatga tactgcgaat cccctgaacc
    16441 aggcggatat ttatggaacc tgctatatga gcgtagacag atttcaggat cagggagatt
    16501 attaccaggc aaaggtgact ctttatgaca gcagctttgg aactggcatc gatttttgga
    16561 attacagcaa aggcgataag ttctggattg aggcagtcgg tgattacgga aaggtcaaat
    16621 cagtttcatt aagtgcatat ggagacgcgt atatggaggt atcctatggc acggagacct
    16681 tcgtttatga tggagaagag gtatggtgct gtggagacgg ttcagaaacc cctgtgctta
    16741 gaaaggtaaa ggagaacgtg gatgtaaaaa ttcctaaaaa tatttccgtt atctctgcgc
    16801 ctggatttga gcagtttacc ttatccctgg acagctattt aaatgattcg gtttataaaa
    16861 tgacgcctgt atttaacgga actaccatcg agaagctgta tgattccttt ataaattatg
    16921 ccgggtaagg acaagatacg cgattggaat aggagataga gccgtgaaca gcacgatgaa
    16981 tgagaattta agagatttgc aggatatcag aaggcaaatg gatatttacc agccaattgg
    17041 ccgggaatat ctacgtcagg tgagatttta caggaattac gagaaggcag tggaacgctg
    17101 gcagcccagt cataaaatta agaatacggc tctgtgcgcg ttgatcatgc ttctggtagg
    17161 cccgcttggc ttaattgctg ccgctgccct ctggtttggg ggacatgata agattctgga
    17221 aattaaagag cgccagaagg gggagcagga aaaaaagatt atggatctgc atgggcagtt
    17281 tctggagaaa tacctgcctg tccaggaaaa atgcgagcgc ctgctcctgg gacaggagga
    17341 ttatgaggtt cccatggcag tggactatct gatttacgtt atctcaaacg agcgggcgga
    17401 aaccatgaaa gaagcttaca atatgctgga tgagcagctt cacagatgga ctatggaaaa
    17461 tatgcagagg gaacagctgg atctgcagag agaacagtgt aagcagctga gacgcatcga
    17521 ggtgaataca acgatcagcg cggccagtga tttgttccat gttatcaatt ctctgtagaa
    17581 tgctggaaca ggaggaaatg ataaatggag ctgttaaaag attatatttc aaaggccttt
    17641 gatttttcag gggaggagac agggcggaac tacaaaaaga tgtgtctgct cagcggagtt
    17701 ttatatataa tattgtatta tgtatggagt ataatacaga aaatagcgat aggcagagta
    17761 ctgctttcat tgttcatacc agtatgcctt ggtgtagtag tgcttgcgtt tgtagcagcg
    17821 acctttcgcc gctgcggatg cacagggcga tcaaaatggt ggtgcgctgt atgtgtgctg
    17881 gcaggacctc tgagttttgt tatactgttt tttgttttag gaagagatta aataattgaa
    17941 tattaagaaa gagcgctgca aaacagccgg ttggaagtgg ccgctgaggc agcgcttttt
    18001 tcgacggatt cagaagttaa acctaggcgg cagccgcatc ctctacggct acgatactct
    18061 gaataccctg gcagataaga aatacgaggc cgacaacctg ggatctgtta tctattcgga
    18121 cagaaaacgg gtgtccctat gagtacgata agaatgacaa tattaccagg ctgacagacc
    18181 ggggtggacg ggaaaccagc tacgagtatg atccgctgaa ccgcctgatt caggtgaaga
    18241 ggcctgacgg aaccgtaagt tcctatacct acaacgccag aaatcaggtt ctggaggcga
    18301 agaatacatg tgtctgcggt tttctcatct ctgattatca gtatacctat gacggagacg
    18361 gaaacagagt cttccagctg aattataatc cagatgcaga gtgcggctat ggaaagaatg
    18421 taagcggcga gattttcatg ccggagcaca gccataacga ggacggaagc ctgactgcgg
    18481 aaggagagct gttcggatat atctgctcag ccacaggccg ggcttatgac ttaacggagt
    18541 atgtaaacga taccaaccga gagcatacag aagtcttcac tgcctttaac attaacacag
    18601 gctttgacat ggagtcctat acctacgccg gaagcagccg cctgtcccgg aataatatct
    18661 ggaacgaggc cagagacgta aaccatgacg agatgagctg ctgcctgtat gacggccagg
    18721 gaagcgtcac agccaatacg tggtataacg gaatggtgac agacgtgtac cagtacgatc
    18781 cctacggtcg catggagctt ggaggagaag gccatacaga tttctacagc tgccgcgcag
    18841 agagctatca taatgaggat gcagaagtga ttatggaagg gtataatata aatatagttg
    18901 gttaagatga ttgggaagga aggtgctatg catgttggca ttaaatggtt attatgacgg
    18961 aacagcgatt caggcgctgg aaaagattaa tgcaaagaaa aatcaaaaat tgattattac
    19021 agttttggat gagttcatag aggaaatacc gaagaagaac agcacctctg ccagaggttc
    19081 gctggcaaag tatgccaata cagctttatg gg
//
LOCUS       DBMDUW010000048        18310 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1816_length_18310_cov_5.119227, whole genome shotgun sequence.
ACCESSION   DBMDUW010000048 DBMDUW010000000
VERSION     DBMDUW010000048.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 18310)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 18310)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18310
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1816_length_18310_cov_5.119227"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(366..453)
                     /locus_tag="ACZPCR_09170"
     tRNA            complement(366..453)
                     /locus_tag="ACZPCR_09170"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(417..419),aa:Ser,seq:gct)
     gene            complement(687..1235)
                     /locus_tag="ACZPCR_09175"
     CDS             complement(687..1235)
                     /locus_tag="ACZPCR_09175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004613314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HIR1231083.1"
                     /translation="MERHIKAPISKEDALSLKSGDYVYITGTIYTARDAAHKRMQEAL
                     DRGEPLPIDLKNNIIYYMGPSPAREGRPIGSAGPTTASRMDRYTPQLLDLGLGGMIGK
                     GKRSPEVIEGIVRNGAVYFAAVGGAGALLSKCITKSEVIAYDDLGTEAVRRLTVENFP
                     AIVVIDAEGNNLYEAAVKNFKA"
     gene            complement(1311..2153)
                     /locus_tag="ACZPCR_09180"
     CDS             complement(1311..2153)
                     /locus_tag="ACZPCR_09180"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008397160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HIR1231084.1"
                     /translation="MRTVRTEDIIKNIKEMCIEANHFLSEDMRQVFEQSVEAEKSPLG
                     SLVLNQLKENLEIAGKDMIPICQDTGMAVVFMKVGQDVHIEGGSLTDAVNEGVRQGYT
                     EGFLRKSVVGDPIKRINTKDNTPAVIHYEITEGDRVDITVAPKGFGSENMSRVFMLKP
                     ADGIEGVKEAILTAVRDAGPNACPPMVIGVGIGGTFEKCALMAKHALTRELKDRPSTP
                     WVRELEDEMLSRINQLGIGPGGLGGGTTAFAVNVETYPTHIAGLPMAVNICCHVNRHA
                     HRVL"
     gene            complement(2303..4849)
                     /gene="gyrA"
                     /locus_tag="ACZPCR_09185"
     CDS             complement(2303..4849)
                     /gene="gyrA"
                     /locus_tag="ACZPCR_09185"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HIR1231085.1"
                     /translation="MEPNIFDKVHDIDLKKTMEKSYIDYAMSVIAARALPDVRDGLKP
                     VQRRVLYSMIELNNGPDKPHRKCARIVGDTMGKYHPHGDSSIYGALVNMAQKWSTRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARLSRISMEMLADINKNTVDFVPNFDETEKEPVVL
                     PSRFPNLLANGTSGIAVGMATNIPPHNLRELIAAVIKIIDNQIEEGRDTSIEELMEIV
                     KGPDFPTGATILGKAGIEEAYRTGKGKIRVRAVTDIETMPNGKSRIVVTEIPYLVNKA
                     RLIEKIADLVKDKRVDGITDLRDESNREGMRICIELRRDVNANIVLNQLLKHTQLQDT
                     FGVNMLALVNNEPKVLNLHQMLTYYLDHQKDVVTRRTKYDLNKAEERAHILEGLLKAL
                     DYIDEVIRIIRGSKNVAEAKASLMERFELSDAQAQAIVDMRLRALTGLEREKLLNEYQ
                     ELEKRIAELRAILADENKLLTVIREEIQIIADKYGDDRRTKIGYDEFDMSAEDLIPDE
                     DVVVAMTNLGYIKRMSSDNFKSQNRGGKGIKGMQTIEEDYIEELLMTTTHHYMMFFTN
                     TGRVYRLKAYEIPEAGRTARGTAIVNLIQLQPGEKITATVPMREFDEDKFLFMATKNG
                     MVKRTPMKEYENVRKNGLQAIVLREDDELIEVKATDNTEDIFLVTKKGMCIRFHETDV
                     RITGRVSMGVIGMKFEPGDEVIGMQMASQGESLLVVSQYGLGKRTPIEEFTSQFRGGK
                     GVRCYRITDKTGDLVGAKLVDESRQIMLITNEGIIIKMKVNTISVIGRNTSGVKLMDI
                     DPESGVVVASIAKVRESSEDEDEELDEEFGTDSDGEDNGEALQGQAEDEE"
     gene            complement(4889..6799)
                     /gene="gyrB"
                     /locus_tag="ACZPCR_09190"
     CDS             complement(4889..6799)
                     /gene="gyrB"
                     /locus_tag="ACZPCR_09190"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006772645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HIR1231086.1"
                     /translation="MGSEYSADQIQILEGLEAVRKRPGMYIGSTSIRGLHHLVYEIVD
                     NSVDEALAGFCSEIDVQINADNSITVTDNGRGIPVDIQKKAGIPAVEVVFTVLHAGGK
                     FGGGGYKVSGGLHGVGASVVNALSQWLEVEIYRDGHIYNQRYERGKSMYPLKVKGDCP
                     ADMHGTRVTFLPDPEIFEETVFDYDTLKVRLRETAFLTKNLKIILRDDRGEKQEKTFH
                     YEGGIKEFVNYLNKGGESLYAPVIYCEGMKDNVYVEVAMQHNDSYTENIYTFVNNINT
                     PEGGTHLSGFKTALTNTFNDYARKNKLLKENEPSLSGEDIREGLTAIISVKLEEPQFE
                     GQTKQKLGNTEARAAVLNVVSGQLTYFLEQNPGVAKIISEKSILAQRARAAARRAREM
                     TRRKSALDGLALPGKLADCSDKNPENCEIYLVEGDSAGGSAKEARSKANQAILPLRGK
                     ILNVEKARLDKIYANAEIRSMITAFGTGIHDDFDISKLRYHKIIIMTDADVDGAHIST
                     LLLTFIYRFMPELIKQGYVYLAQPPLYKVEKNKKIWYAYSDAELNDILKEIGRDQNNK
                     IQRYKGLGEMDAEQLWETTMDPERRILLRVTMDEETTSEVDLTFTTLMGDQVEPRREF
                     IEANAKYGTLDI"
     gene            complement(6813..7898)
                     /gene="recF"
                     /locus_tag="ACZPCR_09195"
     CDS             complement(6813..7898)
                     /gene="recF"
                     /locus_tag="ACZPCR_09195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585017.1"
                     /note="All proteins in this family for which functions are
                     known are DNA-binding proteins that assist the
                     filamentation of RecA onto DNA for the initiation of
                     recombination or recombinational repair; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HIR1231087.1"
                     /translation="MFVESVELKNYRNYEELHMEFDPGTNVLYGDNAQGKTNVLESVY
                     LCATTKSHRGSKDKEIIRFSQDESHIKMMIRKDGVPYRIDMHLKKNKTKGIAINGLPI
                     RRASELFGIVNVVFFSPEDLNIIKNGPAERRRFVDLELCQLNRLYVHALAQYNRTLIQ
                     RNRLLKELSFKPELLDTLDIWDMQLASFGKDVIKSRREFADQLNELIRDIHSHLSGGR
                     EELVIRYEPNTEENELEAALKRSRETDLRQRTTMAGPHRDDLSFVVNGIDIRRFGSQG
                     QQRTAALSLKLAEIELVKKLVKDYPVLLLDDVLSELDSRRQEHLLSGIKHIQTIITCT
                     GLDDLVTHSFHIDRVFQIVNGTVKEEN"
     gene            complement(7914..8123)
                     /locus_tag="ACZPCR_09200"
     CDS             complement(7914..8123)
                     /locus_tag="ACZPCR_09200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009263553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HIR1231088.1"
                     /translation="MEVIKLRDEYIKLGQALKAANLVESGVDAKFAIQDGLVRVNGQV
                     ETQRGKKLCDGDVVEFEGTSVKIEK"
     gene            complement(8241..9359)
                     /gene="dnaN"
                     /locus_tag="ACZPCR_09205"
     CDS             complement(8241..9359)
                     /gene="dnaN"
                     /locus_tag="ACZPCR_09205"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007862616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HIR1231089.1"
                     /translation="MKLSFEKDSLLNGINIVLKAVPSKTTMPILECILIDASGSEIKL
                     TGNDMELGIETKVEGLILEHGKIALEAKLFSDIIRKLSGEDSPIIIESDEKYNTTISC
                     DKSVFKIQGKDGEEFSYIPHIERDRYITLSQFTLKEVIRQTLFSISPNDSNKMMTGEL
                     FEVKDNELKVVSLDGHRMSIRKIILKEHYNDIKVIVPGKTLGEISKILNGDNESEVQI
                     FFSSNHIMFDFDSTLVVSRLIEGEYFRISQMLSSDYETKVSVNRRTFLDSIERASILI
                     RENDKKPIIITISDEGMQLKMNSAFGTMSAEVGITKYGKDLMIGFNPKFLIDALRIID
                     DEEVTLYMMNPKSPCFIKDEEENYIYLILPVNFNAAAV"
     gene            complement(9646..11016)
                     /gene="dnaA"
                     /locus_tag="ACZPCR_09210"
     CDS             complement(9646..11016)
                     /gene="dnaA"
                     /locus_tag="ACZPCR_09210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HIR1231090.1"
                     /translation="MLEKIKEKWEEILLHIKEEHELSDVSFKTWLLPTEVYSMKGDTV
                     QILVPDIHFLGYMQKKYGFLITVAIAEITGIECSVDFITREQIKEAPAEVSDNQLLSR
                     PSDVDQQVIQNANLNPRYTFDTFVVGANNNLAHAASLAVAESPGEIYNPLFIYGGVGL
                     GKTHLMHSIGHFILKNNPKAKILYVTSEKFTNELIDAIRNKNNISTTEFREKYRNNDV
                     LLIDDIQFIIGKESTQEEFFHTFNALYEAKKQIIISSDKPPKEIETLEERLRSRFEWG
                     LTVDIQSPDYETRMAILRKKEELEGYNIDNEVIKYIATHVKSNIRELEGALTKIVALS
                     KLNKREITTDLAEEALKDLISPGGAREITPELIIQVVSEHFGITPADISSKKRNKEIV
                     YPRQIAMYLCRTMTSTPLQGIGKCLGDRDHTTIIHGAEKITADLEKNESLRSTLEILK
                     KKLSPQ"
     gene            11565..11699
                     /gene="rpmH"
                     /locus_tag="ACZPCR_09215"
     CDS             11565..11699
                     /gene="rpmH"
                     /locus_tag="ACZPCR_09215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012201940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HIR1231091.1"
                     /translation="MKMTFQPKKRQRAKVHGFRARMSSAGGRKVLAARRAKGRAKLTA
                     "
     gene            11805..12161
                     /gene="rnpA"
                     /locus_tag="ACZPCR_09220"
     CDS             11805..12161
                     /gene="rnpA"
                     /locus_tag="ACZPCR_09220"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013274847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HIR1231092.1"
                     /translation="MKRFNSIKKYGDFQKVYKTGKSYANRLLIMYVMRTKEETDTRIG
                     ISVSKKVGNSVVRHHITRLLRESYRLNKDMVKTGLDIVVVARAAAKDSNFRQIESAYL
                     HLCGLHNILENRSEKN"
     gene            12161..12370
                     /gene="yidD"
                     /locus_tag="ACZPCR_09225"
     CDS             12161..12370
                     /gene="yidD"
                     /locus_tag="ACZPCR_09225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015541427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HIR1231093.1"
                     /translation="MKKICIFMIRGYQKYISPMTGPHCKYTPTCSQYAIEALQKYGAL
                     KGGFLACRRILRCHPFAEGGYDPVP"
     gene            12389..13636
                     /locus_tag="ACZPCR_09230"
     CDS             12389..13636
                     /locus_tag="ACZPCR_09230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006772635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HIR1231094.1"
                     /translation="MELFVATKAGSILGPFASLFGIVMDLLFRFTSSFGIFNIGICII
                     LFTIITRLLLFPLTLKQQKSSKMMALMNPEIAAIQKKYKGKTDQTSMAKQQVEMQAVY
                     EKYGSSPMAGCLPMLIQFPIILALYRVIYNIPAYVPSVRVFFDNVVEPLQNQPGFAEK
                     LIEIGGKMSTGFTAEALSGSADKVVDLLYKFTPENWAMLQNAFPTISEVIAQNADKIE
                     QMNSFFGINLATAPFTGFTNITIAWAIPILAGLTQWYSTKLMSSTQNTDPDAPGAQMM
                     NSMMIMMPLMSVFFCFTLPAGIGIYWVVQGIILIFQQMFVNSYMKKVDMDELIKKNVE
                     KMNKKRAKKGLPPAKINQNAAASLKNIQAKQEAEEAELNRRLERNAKQIKDSTEFYNS
                     DPKPGSLASKARMVQKYNEKHNK"
     gene            13649..14299
                     /gene="jag"
                     /locus_tag="ACZPCR_09235"
     CDS             13649..14299
                     /gene="jag"
                     /locus_tag="ACZPCR_09235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HIR1231095.1"
                     /translation="MDMITVSAKTVDEAVTKALIELETTSDKLEYEVVEKGSSGFLGI
                     GAKPAVIRAKKKERIEDRAIDFLNQVFQSMNMEVSITAEYNPEEREMNINMEGSDMGI
                     LIGKRGQTLDSLQYLVSLVVNKKKEEYIRVKLDTENYRERRKETLETLAKNIAYKVKR
                     TKHSVSLEPMNPYERRIIHAALQNDKYVVTRSDGEEPFRHVIISLKRDGKKEKTDR"
     gene            14512..15885
                     /gene="mnmE"
                     /locus_tag="ACZPCR_09240"
     CDS             14512..15885
                     /gene="mnmE"
                     /locus_tag="ACZPCR_09240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HIR1231096.1"
                     /translation="MNNDTIAAVSTALTNSGIGIIRISGDRAVETADRIFRKPNGRKL
                     KDEKTFTIHYGHIYDGDQMIDEVLVMLMRGPKSYTAEDTVEIDCHGGVLVMKKVLETV
                     IKNGARPAEPGEFTKRAFLNGRIDLSQAEAVIDVINAKNDYALKSSVSQLNGAMSKKI
                     KKLREELIYEIAFIESALDDPEHISLDGYPEQLRGRLAPVKSELRRLLASADNGRVVK
                     EGVKTVILGKPNAGKSSLMNVLVGEERAIVTDVEGTTRDILEEHIRLHGISLNIVDTA
                     GIRETDDIVERIGVDRARHTADEADLIIYVVDGSRPLDENDREIIELIRGRKAIVLLN
                     KTDLQMAVDEEQLRETVGQPVIPVSAKEQKGIDALEEQIKEMFLSGDIDFNDEVMITN
                     IRHKAALKEALDSLELVERSIDDGMPEDFFSIDLMNAYEQLGTIIGEALEDDLVNEIF
                     SRFCMGK"
     gene            16095..17987
                     /gene="mnmG"
                     /locus_tag="ACZPCR_09245"
     CDS             16095..17987
                     /gene="mnmG"
                     /locus_tag="ACZPCR_09245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006772632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HIR1231097.1"
                     /translation="MPHLEETYDIAVVGAGHAGCEAALAAARLGMETVVFTVSVDSIA
                     LMPCNPNIGGSSKGHLVRELDALGGEMGKNIDRTFIQSKMLNQSKGPAVHSLRAQADK
                     EMYTRQMRLVMENTDHLTIKQAEITEILTEEGKVIGVKTLSGAVYHCRAVVLATGTYL
                     RARCIYGEVSNPTGPNGLQAANHLTDSLKALGIEMYRFKTGTPARVDRRSIDFSKMEE
                     QFGDERVVPFSFTTDPKSVQKEQVSCWLTYTNEKTHQIIRDNLDRSPLFSGAIEGTGP
                     RYCPSIEDKVVKFPDKERHQVFVEPEGLYTNEMYLGGMSSSLPEDVQTAMYRTVPGLE
                     QVKIVRNAYAIEYDCINSRQLKATLEFKAVEGLFSGGQFNGSSGYEEAAVQGFMAGVN
                     AARKLMGKEAVVLDRSQAYIGVLIDDLVTKESHEPYRMMTSRAEYRLLLRQDNADLRL
                     SGIGHEIGLIDDERYERVVRKERQIREEVERLNQLPVGANSQVQECLRKYGSTELKSG
                     ATMAELIRRPELSYEAVKEIDPKRPDLDWDVAEQVNINIKYEGYIRRQLQQVAQFKKL
                     ESRKLDEHFDYSSVKSLRKEAVQKLNLYKPMNIGQASRISGVSPADISVLLVHLEQMK
                     HQKGRE"
BASE COUNT         4599 a         4310 c         4539 g         4862 t
ORIGIN      
        1 taaagttttg attccagtcc aaaacttagc ttggctaatt tttaaaccgt tttactgttt
       61 ttaggttgtt ctgaatgttc tctcgaactt caaggctcct gagccttttt gttcttagaa
      121 ttttcagggt tttacatact gttcagtttt caaggttcgt tgttgtttct caacagtaac
      181 tcgtttatct tatcacaact cgttgtgttt gtcaacaact ttttttattt attttttgaa
      241 gttctttcaa gcttccgtgc cgctctcagc gacgcgttat atcttatcac aactccgtgt
      301 cagtgtcaag cacttttttg aagtttttta agattttgtt ttatctctct tttggaaaga
      361 taaagcggag aaagagggat ttgaaccctc gcgccggttg cccgacctac acccttagca
      421 ggggcgcctc ttcggcctct tgagtatttc tccgaattgc ttgttttata tagtttcttt
      481 ggcttgtctg cctcagaagc aaggcccatt atactagaga taccaagcct tgtcaagcct
      541 atttttataa ttattttgat aaatctttat aagaatggct catggatttt acagatcagg
      601 ttttttgtct tttctgacag agctttttcc ctgagcttcc ccggtaacag gccgaagaag
      661 gctcagggaa tcgttttccg gctctatcag gctttaaagt tcttcacagc cgcttcatat
      721 aaattatttc cctctgcgtc aatcacaaca atagccggga aattctctac agtcaggcgg
      781 cggactgcct ctgtccccag atcgtcgtag gcaatcactt ctgatttcgt gatacatttt
      841 gacagaagcg ctcctgctcc tcccactgcc gcaaaataga cagctccatt tctcacaatc
      901 ccctctatta cttcagggct tctctttccc tttccaatca ttccgcccag gcccaggtcg
      961 agaagctgcg gcgtatagcg atccatacgg ctggctgtgg tcgggcctgc tgaaccgatg
     1021 ggacggccct ctctggccgg ggaaggtccc atatagtaaa tgatgttgtt cttcagatca
     1081 atgggcagag gctctccccg atccagcgct tcctgcatgc gcttgtgcgc tgcgtctctg
     1141 gcagtgtaaa tcgttcctgt aatataaaca tagtcccccg attttaagga gagggcgtcc
     1201 tctttgctga tcggcgcttt gatatgacgt tccatatacg gattcctgcc tttctctttg
     1261 tctatatctt attatatata tcttttacat cggtctgtat cggtcagccg ctacagcact
     1321 ctgtgggcgt ggcggtttac atggcagcag atattaactg ccatcggaag ccctgcgatg
     1381 tgggtcggat acgtctccac attcactgca aacgcagttg tcccgccgcc caggcctccg
     1441 ggaccgattc ccagctgatt gattctggac agcatctcat cctccagttc tctcacccag
     1501 ggagtcgaag ggcggtcctt cagttccctg gtcagcgcat gcttggccat aagggcgcat
     1561 ttttcaaacg ttcctccgat ccccactccg attaccatag gagggcaggc gttcggcccc
     1621 gcgtccctga ctgctgtgag aatagcctcc ttgacgccct ctatgccgtc tgcaggcttc
     1681 agcataaata cgcggctcat attctcgctt ccgaatcctt tcggagctac tgtaatatca
     1741 acccgatctc cctctgtaat ctcatagtga atcaccgccg gcgtgttgtc ctttgtatta
     1801 atccttttga taggatctcc caccacggat tttctgagaa agccctctgt atatccctgg
     1861 cgcacgcctt cattgactgc gtctgtcagg cttccccctt ctatatgtac gtcctgtccc
     1921 actttcataa atacgaccgc catacctgta tcctggcaga tagggatcat atctttgcct
     1981 gcaatctcta aattttcctt cagctggttt aatacaaggc ttccaagagg cgatttctca
     2041 gcctccaccg attgttcaaa gacctgtctc atatcctctg acagaaagtg gttggcctcg
     2101 atgcacattt ctttaatatt tttaatgatg tcttctgttc ggactgttct catggatctc
     2161 tcctcctgac ataaccgatg atgccgtttt gttctaaaag cagacagaca ggctccggcc
     2221 ccaaatctcc cggccagggc ctgtctgctg ttatcttata agcgcgccta catgtttcct
     2281 tctttttcca ggttctgctg ctctattcct cgtcttctgc ctgtccctgg agcgcctctc
     2341 cattatcttc gccgtctgaa tctgtgccga attcctcatc cagctcttca tcctcgtcct
     2401 cactgctctc gcggaccttg gcgatgctgg ctaccacaac acctgactcg ggatcaatat
     2461 ccatcagttt gacgccggaa gtattcctgc caatcacaga aatcgtattc accttcattt
     2521 taatgatgat tccctcattg gtgataagca tgatctgacg gctctcatct accagcttgg
     2581 ctcccaccag gtctcccgtc ttatctgtaa tgcggtagca tctcacgcct tttccgcccc
     2641 tgaactggct ggtgaactct tcgattggag tccgttttcc aagaccatac tgggagacaa
     2701 ccagcaggct ttctccctgg cttgccatct gcataccgat gacctcgtcg cccggctcaa
     2761 acttcattcc gataacgccc atggaaacgc ggcctgtgat tctcacgtct gtctcgtgga
     2821 agcggatgca cattcccttc ttcgtcacca ggaaaatatc ctctgtgtta tcagtagcct
     2881 taacctcgat cagctcgtcg tcttctctga gaacaatggc ctgaagaccg ttctttctca
     2941 cattctcgta ctccttcatc ggagtccgct tcaccatgcc gttcttggtg gccataaaca
     3001 ggaatttatc ctcgtcaaat tccctcatag gcacagtggc ggtaattttc tcgcccggct
     3061 gcagctgaat caggttcaca atcgccgttc ccctggctgt tctgcctgcc tccggaatct
     3121 cgtaggcctt taaccggtag acgcgtcccg tgttggtgaa gaacatcata tagtgatgag
     3181 tggtggtcat cagaagttcc tcaatgtagt cctcctcaat ggtctgcatt cccttgattc
     3241 ccttgccgcc tctgttctgg ctcttaaagt tatcgctgga catgcgctta atgtagccta
     3301 aattggtcat agctaccacc acgtcctcgt ctggaatcag atcctctgct gacatatcga
     3361 actcatcgta gccgatcttc gttcttctgt cgtctccgta cttgtcggcg ataatctgaa
     3421 tctcctcccg gatgacggtt aaaagcttgt tttcgtctgc caggatagcg cgcagctctg
     3481 caatgcgctt ttccagctcc tggtactcgt ttaaaagctt ttctctctcc agtccggtga
     3541 gagcgcgcag tctcatgtcc acaatggcct gggcctgagc gtctgaaagc tcgaaccgct
     3601 ccatcaggga cgccttggcc tccgccacat tcttggaacc gcggatgatt cggatgacct
     3661 cgtcaatata gtctaaagcc tttaaaagtc cctctaagat gtgggctctc tcctcagcct
     3721 tgttcagatc gtattttgtc cttctggtga cgacgtcctt ctggtgatcc agatagtagg
     3781 tgagcatctg atgaagattc agcaccttcg gctcgttgtt taccagagcc agcatgttga
     3841 cgccgaaggt atcctgcagc tgcgtgtgct ttaacagctg gtttaatacg atattggcgt
     3901 tcacgtcgcg gcgcagctcg atacagatgc gcatgccttc ccggttggac tcgtctctca
     3961 gatccgtgat tccgtccacc cgtttgtcct ttacaaggtc tgcaatcttc tcaatcaggc
     4021 gggccttatt gactaagtac gggatctctg tgactacaat gcggctcttg ccgtttggca
     4081 tggtctcgat atccgtcacc gcgcggacgc ggatctttcc ctttcctgtg cggtaggcct
     4141 cctcaattcc ggccttgccc aggatggtag cgcctgtagg gaaatctggt ccctttacga
     4201 tctccatcag ttcctcgatg gaggtatctc ttccctcctc gatctgattg tcaataatct
     4261 ttatgacagc tgcaatcagc tctcttaaat tgtggggcgg aatattggtg gccatgccta
     4321 ctgcgattcc ggatgttccg ttggctaaca ggttcggaaa acgggaggga agcaccaccg
     4381 gctccttctc cgtctcatcg aagttgggca cgaaatccac tgtgttttta ttgatatcag
     4441 ccagcatttc catggaaatt ctgctcagtc tggcctccgt ataacgcatg gccgccgcgc
     4501 cgtctccgtc tacggatccg aagtttccgt ggccgtctac cagcatatag cgggtagacc
     4561 atttctgggc catattcacc agggctccgt aaatagagct gtctccgtgg ggatggtatt
     4621 tacccatggt gtcgccgacg atacgggcgc actttctgtg gggcttatct gggccattgt
     4681 ttaactcgat catggagtag agcacgcggc gctgaaccgg ctttaaaccg tcccgcacgt
     4741 ctgggagggc acgggccgcg ataacgctca tggcgtagtc aatgtaggac ttctccatgg
     4801 tcttttttaa atctatgtca tgaactttgt caaaaatatt tggttccatt ctctatcctc
     4861 caaaatgggg agctttgacg ctcacgcttt aaatgtcaag ggttccgtac tttgcgttgg
     4921 cttcgatgaa ctcgcgtcgc ggctctacct ggtctcccat cagcgtggta aaggttaagt
     4981 ccacctcgct ggtagtttcc tcatccatgg ttacccgcag aagaatgcgc ctctccggat
     5041 ccatggtagt ctcccagagc tgctctgcgt ccatctctcc cagtcccttg tagcgctgga
     5101 ttttattgtt ctgatccctg ccgatttctt ttaaaatgtc atttaactcg gcatcgctgt
     5161 aggcatacca gattttcttg tttttctcca ccttgtaaag cggaggctgt gccagataca
     5221 cataaccctg tttgattaat tccggcataa agcggtaaat aaaggtcagc agcagggtgc
     5281 tgatatgggc gccgtccaca tcggcatctg tcataataat aatcttgtgg tagcggagct
     5341 tggaaatatc gaagtcgtcg tgaattcccg ttccaaacgc cgtgatcatg gaacgaatct
     5401 cagcgtttgc atagatcttg tccagtctgg ctttctccac gttcagaatc tttcctctca
     5461 gaggcaggat ggcctggttt gccttgcttc tggcttcctt ggcggatccg ccggcggaat
     5521 ctccctctac caggtagatc tcgcagttct ccggattctt gtcagaacag tctgccagct
     5581 ttccaggcag agccaggccg tccagagcgg actttcttct ggtcatctcc ctggcacgtc
     5641 tggcagccgc cctggctctc tgggccagaa tggatttttc gctgatgatt ttcgcaacgc
     5701 ccgggttctg ctccaggaaa taggtcagct gcccgcttac cacgttcagc acagccgccc
     5761 tggcctccgt attgccaagt ttctgcttgg tctggccctc aaactgcggc tcctccagct
     5821 tcacgctgat aatcgcagtc aggccctccc tgatatcctc tccggaaaga gacggctcgt
     5881 tctcctttaa cagcttgttc tttctggcat agtcgttaaa ggtgttggtg agggccgtct
     5941 taaagccgct caggtgcgtt ccgccctccg gcgtgttgat gttgttgacg aaggtataaa
     6001 tgttctctgt gtaggagtca ttgtgctgca tggcaacctc cacatacacg ttgtccttca
     6061 ttccctcgca gtaaatgaca ggagcgtaga gactctcgcc tcccttgttt aaatagttga
     6121 cgaactcttt gattccgccc tcgtagtgga aggttttctc ctgcttttcc cctctgtcgt
     6181 cccttaaaat aatcttcagg ttcttggtca aaaaggcagt ttcccgcagt ctcactttta
     6241 aggtatcgta gtcaaagacc gtctcctcaa agatctccgg atccgggagg aaggtgactc
     6301 tcgttccgtg catatcagcc ggacagtctc ccttcacctt cagaggatac atggatttgc
     6361 ctctctcgta tctctgatta taaatgtggc cgtccctgta gatttccact tccagccact
     6421 gggacaaggc gtttacaacc gacgctccta cgccgtggag tccgcctgat accttgtatc
     6481 ccccgcctcc gaacttaccg cctgcgtgga gcacagtaaa gacaacctca actgccggga
     6541 ttcccgcctt tttctgaatg tccaccggaa ttccacgtcc gttgtctgtg actgtaatgg
     6601 aattatctgc attgatctgc acgtcaatct cactgcagaa gcctgccagg gcctcgtcca
     6661 cggagttgtc tacgatttcg tataccagat ggtgaaggcc tcttatggag gtactaccga
     6721 tatacattcc cgggcgcttt ctcaccgctt ccagcccctc taaaatttgt atttgatctg
     6781 cgctgtattc tgaacccata agttcctcct aactaatttt cttccttaac agttccgttt
     6841 acgatctgga atacccggtc aatgtgaaag gagtgggtga caaggtcgtc cagccccgta
     6901 caggtaatga tcgtctgaat gtgcttaata ccggaaagca gatgctcctg cctgcgggag
     6961 tcaagctctg aaagcacgtc gtccaaaaga agcacagggt aatcctttac cagcttcttc
     7021 accagctcga tctccgccag ctttaaggac agagccgccg tcctctgctg cccctgggag
     7081 ccgaagcgcc ggatgtcaat gccattaacc acaaagctta aatcgtccct gtgtgggccc
     7141 gccatggtgg ttctctgcct gagatccgtc tccctgcttc gtttcagagc cgcttccagc
     7201 tcattctcct ccgtgtttgg ctcatagcgg atcacaagct cctccctgcc tcccgacaga
     7261 tggctgtgaa tgtcccggat cagctcgttt agctggtccg caaactccct tcggctctta
     7321 atcacatctt ttccaaagga cgccagctgc atatcccaga tatccaaggt atctaaaagc
     7381 tccggcttaa aggaaagctc ctttaaaagc cggttgcgct gaattaaagt ccgattgtac
     7441 tgtgccagcg cgtgaacgta aagccggttc agctggcaca gctccagatc tacaaaacgc
     7501 ctgcgctctg caggcccgtt ttttataatg tttaaatcct ccggagaaaa aaataccacg
     7561 tttacaatcc caaacagctc gctggctctg cggatgggaa ggccgttaat ggcgattccc
     7621 ttggtcttgt tttttttcag atgcatgtca atccggtagg gcactccatc cttgcggatc
     7681 atcatcttaa tatgggattc gtcctgggaa aaccggatga tctccttatc cttgctgcct
     7741 ctgtgggact tggtggtcgc gcagaggtaa accgactcca gcacgttcgt ctttccctgg
     7801 gcgttgtccc cgtaaaggac gttggttccg ggatcgaact ccatgtgaag ctcctcgtaa
     7861 ttgcggtaat tttttaattc gactgattct acaaacatat ggctccagtt ttcctatttt
     7921 tcaattttaa cggaggttcc ctcaaattcc accacgtccc cgtcgcagag tttttttcct
     7981 ctctgggttt ccacctggcc gttgaccctc accagaccgt cctgaatggc aaacttggcg
     8041 tctacgccgg attccaccag attggcggcc ttcagcgcct ggcccagttt aatgtactcg
     8101 tctctaagct taattacttc catggttgaa acggctcctt ttaccgtata tttatacatt
     8161 tatgcattat tttgtcttcc tgcggcgcac acattttcgc ttttttgaag gagcggacgc
     8221 cgcattccgg ccccgtctgt ttagacggcg gctgcgttaa agttgaccgg aaggatcaga
     8281 tagatataat tttcttcctc gtccttaata aagcacgggg acttaggatt catcatatag
     8341 agagttacct cttcgtcgtc aatgatccga agggcgtcga tgaggaattt gggattaaat
     8401 ccaatcatca gatccttgcc gtatttggta atgcccacct cggcgctcat ggttccgaag
     8461 gcagagttca tttttagctg cattccctca tcactgatgg taatgatgat cggttttttg
     8521 tcattttcac ggatcaggat gctggcgcgc tcaatactgt ctaagaaagt ccggcggttt
     8581 acgctgactt tcgtctcata atcgctggag agcatctggc tgatccggaa atactctccc
     8641 tcaatgagac gggacaccac cagagtggaa tcgaagtcaa acataatgtg gttggagctg
     8701 aagaaaatct gtacttctga ttcattgtcc ccgttcagaa tcttgctgat ctcaccgaga
     8761 gttttgccgg gaacgatcac ctttatatca ttataatgct cttttaagat aatttttcgg
     8821 atagacatgc ggtgtccgtc cagggaaacg acttttaatt cgttgtcctt tacctcaaac
     8881 agctcgcctg tcatcatctt gttgctgtcg tttggtgaaa tagagaaaag agtctgacga
     8941 atcacttctt ttaatgtaaa ctgagagaga gtaatgtagc gatcccgctc aatgtggggg
     9001 atgtagctga attcctcccc gtcctttccc tggattttga aaacagattt atcgcaggaa
     9061 atggttgtgt tgtatttttc atcagattct atgataatcg gagaatcttc tccggataat
     9121 tttctgataa tatcggaaaa aagctttgct tccagggcaa tttttccatg ttctaaaatc
     9181 aggccttcta cttttgtctc aatgccaagt tccatatcgt ttccagtcag cttgatctct
     9241 gatccggagg catcgataag aatacattct aaaatcggca tagttgtttt ggaaggtaca
     9301 gcctttaaaa caatgttgat gccgtttaac agtgagtctt tttcaaatga tagcttcata
     9361 gttgttgata actcctttgc tgaaaaaatg aaacgcagtg taagtaaaga tataaataaa
     9421 ttccgccgta atcgccgtag ggggcgtgaa tatgtgtata agtctgaaaa ggccttaaaa
     9481 atcaatgact aatccactgg aaaaaggtgt gtacaagtcg aaaaaaggcg aaggataact
     9541 tgagaattat ccacaggttc aaaacgagtc tgagggacct gaaaatattc ctcaaattat
     9601 ccacagagta tccagacggt tttccacgtc cattgtggat gggcgttact gcgggctcag
     9661 ttttttcttc agtatttcaa gtgtgctgcg gagagactca tttttttcca gatcagctgt
     9721 aattttttct gctccatgga taatcgtggt gtgatcccga tctcccagac actttccaat
     9781 tccctgaaga ggggtgctgg tcatggtgcg gcacagatac atggcaattt ggcgcggata
     9841 aacgatctct ttattgcgtt ttttggagga aatatcagcc ggggtgatgc caaaatgctc
     9901 ggaaaccacc tggataataa gttccggcgt aatttctcgg gctccgcctg gtgaaatcag
     9961 gtcttttaag gcttcctccg ccagatcggt agtgatttcc ctcttattta atttggaaag
    10021 agccacgatc tttgtcagcg ccccctccag ctcgcggata ttggatttca catgggtggc
    10081 gatatatttg atgacttcgt tgtcaatgtt gtagccctcc agctcctcct ttttgcgcag
    10141 gatggccatt cgcgtttcat aatccggaga ctggatatct acagtcaggc cccattcaaa
    10201 acgggagcgg agacgttctt ccagcgtctc gatctccttg ggaggcttat cggaggaaat
    10261 aataatctgc tttttcgcct cataaagggc gttgaaagtg tggaaaaatt cctcctgcgt
    10321 gctctccttt cctataataa actgaatatc gtcgatcagg agaacgtcgt tgtttctgta
    10381 cttttcgcgg aactccgtgg tggagatatt gtttttatta cggatggcgt cgatcagctc
    10441 gttggtgaac ttttcgctgg tcacgtataa aattttggct ttcgggttat ttttaaggat
    10501 aaaatggccg atggaatgca tcaggtgggt ttttccaagt cccactcctc cataaataaa
    10561 gaggggattg taaatttcac ctggagattc ggctaccgca agggaagccg catgggccag
    10621 attattgttg gcgcccacga cgaaggtgtc gaaggtgtac cggggattta agttggcgtt
    10681 ctggatcacc tgctgatcca cgtcggaagg cctggagaga agctgattat cagaaacttc
    10741 tgccggcgcc tccttgattt gttctctggt aataaaatca acgctgcact cgattcccgt
    10801 aatttctgcg atggccacgg tgatcagaaa accgtacttt ttctgcatgt accctaaaaa
    10861 atggatatca ggaaccagaa tctgaacggt gtcgcccttc atggaataaa cctctgtcgg
    10921 cagcagccag gtcttaaagg atacgtcgct cagttcgtgt tcttccttaa tatgcaacag
    10981 aatttcttcc catttttctt tgattttttc taacatagta gatctcctaa atatattaaa
    11041 gaagcaaaac tgcaaatttg cccaatctaa tcatatttta catgattaca aatcaatttt
    11101 caatggaaat gtgaaaaagt tggggataac ttatggggat aagtggaaaa aaggatatac
    11161 acagaataga ttccacaaaa catgaggaaa tacaagagat tgggaaaaat agaaaaaatt
    11221 gtacacaggt tgtccagaag ttattcagtg agttatcaac aagttatcaa cagcttgggg
    11281 ataaattatg taaagcgtgt gaataaatgt gggataattt gtggacagcg cataaaaaag
    11341 actgtaaaat caacaggtta caagatgttg tggcggtgga taagttatcc acaagaagat
    11401 gggagggaaa aataagaggg agagaaaagc gcgggaaatg cagaaaatac ttgactactg
    11461 cggggttgtt ctatataatc aagaagatgt ttagtttaaa atagtctaac tatggataag
    11521 acaaattctt tgataatcag atgaatgagg aggtgttttg aattatgaag atgacatttc
    11581 agcctaagaa aagacagaga gctaaagttc acggcttcag agctagaatg agcagcgcag
    11641 gcggaagaaa ggttctggct gcaagaagag caaagggaag agcaaaatta actgcttaat
    11701 gaagcgtggc cgcaattttc actgtaaaat tgtggccttt tcttttctca aactttaacg
    11761 ctccgcggga atgcggggcg agtcctgaag cgaggggaga atgcatgaag cgttttaatt
    11821 cgatcaaaaa gtacggggat ttccagaagg tgtataaaac cgggaaatcc tatgcaaacc
    11881 ggcttttgat tatgtatgtg atgaggacga aggaggagac cgatacgagg atcgggattt
    11941 ccgtcagcaa aaaagtgggg aacagcgtgg tgcgccatca cattacaaga cttttaaggg
    12001 agagctaccg actgaacaag gacatggtta agactggact ggacatcgtg gtggtcgcga
    12061 gagcggctgc aaaagactcg aatttcaggc agatagagag cgcctatctg catctgtgcg
    12121 gacttcataa cattttagag aatcgaagtg agaagaattg atgaaaaaga tctgtatttt
    12181 catgatccgg gggtatcaga agtatatttc ccccatgaca ggacctcact gtaagtacac
    12241 gcctacgtgt tctcaatacg ccattgaggc acttcagaag tacggcgcgt taaaaggtgg
    12301 ttttttggcc tgcaggcgga tactcagatg tcatcccttt gcagaaggcg gttatgatcc
    12361 ggttccttag caagtaggag gtagttaatt ggaattattt gtagcgacta aggcaggctc
    12421 aattttaggg ccgtttgcca gcctgtttgg aattgtcatg gacctgctgt tccgtttcac
    12481 cagcagcttc ggcattttca acattggtat atgtattatt ttatttacca tcattacaag
    12541 acttcttctg tttccgctta ccttaaagca gcagaaatcc tctaagatga tggctctgat
    12601 gaatccggaa attgcagcga ttcagaaaaa atataaggga aagaccgatc agacttccat
    12661 ggcgaagcag caggtggaga tgcaggcggt ttatgagaaa tacggctcct cccctatggc
    12721 aggatgcctt cccatgctga ttcagttccc gattatttta gctctgtacc gcgttattta
    12781 caacattccg gcgtacgttc cttctgtaag agtgttcttt gacaacgtgg tggagcctct
    12841 tcagaatcag ccgggttttg cggaaaagct gattgaaatc ggcggaaaga tgagcactgg
    12901 ctttacggct gaggctttat ccggatctgc tgataaggtc gtggatctgc tttataagtt
    12961 cacaccggag aactgggcga tgcttcagaa cgcatttccg actatttccg aggtgattgc
    13021 ccagaatgca gacaagattg agcagatgaa ctctttcttc gggattaacc tggccactgc
    13081 gccgtttaca ggctttacga acattaccat tgcctgggcg atcccgattt tagccggtct
    13141 gactcagtgg tattccacaa agctgatgtc aagcacacag aatacagatc ctgacgctcc
    13201 gggagcccag atgatgaaca gcatgatgat tatgatgccg ttaatgtctg tattcttctg
    13261 cttcactctg ccggccggta tcggtattta ctgggtagta cagggtatta tcctcatttt
    13321 ccagcagatg tttgtcaact cctacatgaa gaaggtagac atggacgagc tgattaaaaa
    13381 gaatgttgag aagatgaaca aaaagcgtgc gaagaaagga cttcctccgg caaagatcaa
    13441 tcagaacgcc gctgcaagcc ttaagaacat tcaggcgaag caggaggctg aggaggctga
    13501 gctgaaccgc agactggaga ggaatgcaaa gcagatcaag gattccaccg agttctacaa
    13561 ctcagatccg aagcctggca gccttgcgtc caaggccaga atggttcaga agtacaacga
    13621 aaagcacaac aaataggagg ggtgcagtat ggatatgatc acagtttccg caaagacagt
    13681 ggatgaagct gttacaaaag cgctgatcga gcttgagacg accagtgaca agctggaata
    13741 tgaggttgtg gagaagggga gttcaggatt cttaggaatc ggcgcaaagc cggcggtaat
    13801 cagagcgaag aagaaagagc ggatcgagga tcgggccatt gatttcctga atcaggtgtt
    13861 ccagtccatg aatatggagg tttccatcac agccgagtac aacccggagg agagggaaat
    13921 gaacattaac atggaaggct ccgatatggg aattctgatt ggcaagagag gccagacgct
    13981 ggattctctc cagtatcttg taagccttgt ggtgaacaag aagaaggaag aatatatccg
    14041 cgttaagctg gatacggaaa attaccgcga gagacggaag gaaactctgg aaactctggc
    14101 taaaaatatc gcctacaagg taaagagaac aaagcattcc gtttcccttg aaccgatgaa
    14161 cccatatgaa agacggatta tccatgcagc acttcagaac gataagtacg ttgtgacaag
    14221 aagcgatggg gaagagccat tccgacacgt aattatctct ctgaagagag acggaaaaaa
    14281 agaaaagacg gacagatagc agcaaagaca gcttgcaata tccgaaaaca gcgattcagg
    14341 cagggagcag gctccctgcc tgtgctgatt taaagaaaag aacggtgctg aatttatatt
    14401 atgctgtttt acaaggaaag ggattccggg cgcgggatca ttttccttat aaaacagaaa
    14461 caaagacagg agacagaaga acaggaggcg aagaaagcta tgattcatac gctgaataac
    14521 gataccattg cagctgtttc tactgcgctt accaattccg gaatcggcat tatccggatc
    14581 agcggggaca gggcagtaga gacggccgac aggattttca gaaaaccgaa cggcagaaag
    14641 ctgaaggatg aaaagacatt taccatacac tacggtcata tttacgacgg agaccagatg
    14701 atcgacgagg tgctcgtcat gctgatgcgg gggccgaaga gctatactgc ggaggacaca
    14761 gtggagatcg actgccacgg aggcgtcctg gtgatgaaaa aagtcctgga gactgtaatt
    14821 aaaaacgggg ccagaccggc ggagccgggg gaattcacaa agagggcttt tttaaacgga
    14881 agaatcgacc tgtcccaggc tgaggcggtc atcgacgtca tcaacgcgaa gaacgactat
    14941 gccctgaaaa gctcggtgag ccagttaaac ggcgccatgt cgaaaaaaat taagaagctg
    15001 cgggaagagc tgatttacga gattgccttt attgagtcgg ccttagacga tccggagcat
    15061 atttccctgg acggctatcc agagcagctg agaggccgtc tggcgcctgt gaagagtgag
    15121 ctgaggcgtc ttctggcgtc cgcagacaac ggccgtgtgg tgaaggaggg ggttaagacg
    15181 gtgattctgg gaaagccgaa cgccggaaaa tcctcgctga tgaacgtgct ggtgggagag
    15241 gagagagcga ttgtcacaga tgtggagggc acgaccaggg atattctgga ggagcacatc
    15301 agacttcatg gaatcagctt aaatattgtg gatacggccg gtatcaggga gacggacgac
    15361 atagtggagc ggatcggtgt ggaccgggca aggcacacag cggacgaggc ggatctgatt
    15421 atttatgtgg tggacggttc caggcctctg gatgagaatg acagggagat tatagagctg
    15481 atccggggca gaaaagccat cgtgctgtta aataagacgg atcttcagat ggctgtggac
    15541 gaggagcagc tgagagagac agtgggacag ccggtcattc ctgtttcggc taaggagcag
    15601 aagggaatcg acgcgctgga ggaacagatt aaggaaatgt ttctgtcagg agacattgat
    15661 tttaacgacg aggttatgat caccaatatc cgccataagg cggcgctcaa ggaggccctg
    15721 gacagcctgg agctggtgga gcgaagcatt gacgacggaa tgccggagga ctttttctct
    15781 atcgatctga tgaacgccta tgaacagctg gggacaatca ttggagaggc gctggaggac
    15841 gatctggtta acgagatctt cagccggttc tgcatgggaa aatagaaaca aaagaaaagc
    15901 ccaaagaaaa gtgcaaagaa aagtgcaaag aaaagcacaa agaaaagcgg gaaataggac
    15961 gcagaagaag cgtaaaaaaa tgaggataag aatatcaaat atatattata taacttatag
    16021 ttatataacg cagaaaacct tataaaatca gagaaaacag ctttggcagc aagaacaagg
    16081 aaggaagata aggtatgccg catttagagg agacatatga tattgcagta gtgggagccg
    16141 gacatgccgg ctgtgaggcg gctctggctg ccgcacggct tgggatggaa acggtggttt
    16201 ttaccgtcag cgtggacagc attgccctga tgccctgcaa tcctaatatt ggaggcagtt
    16261 ctaagggaca tctggtgcgg gagctggacg ctctgggcgg agagatggga aaaaatatag
    16321 acagaacctt tattcagtcg aagatgctga atcagtccaa gggaccagcg gttcactctc
    16381 tgagagctca ggcggacaag gagatgtaca cgcgccagat gcgccttgtg atggaaaata
    16441 cagatcatct gacgattaag caggcggaaa ttacagagat tctcacagaa gagggaaagg
    16501 tgataggggt aaaaaccctt tcaggagctg tctatcactg ccgcgccgtg gtgctggcca
    16561 ctggaacgta tctgagagcc agatgtattt atggcgaggt gagcaatcct acaggcccca
    16621 acgggctgca ggctgccaat cacctgacag attccttaaa ggctctggga atcgagatgt
    16681 accgctttaa aacgggaaca ccggccagag tggacagaag aagcattgat ttttccaaga
    16741 tggaagagca gtttggagac gagagagtgg taccgttttc gtttactaca gatccgaaat
    16801 ctgtccagaa agagcaggtt tcctgctggc tgacttatac gaacgagaaa actcaccaga
    16861 ttatcaggga taacctggac cgttcgccgc tgttttccgg cgccatagag ggaaccggac
    16921 ccagatactg tccgtccatt gaggataagg tcgtaaaatt ccctgataaa gagcggcatc
    16981 aggtttttgt ggagccagaa ggactctata ccaatgaaat gtatctggga ggaatgtcca
    17041 gctctctgcc ggaagacgtg cagacagcca tgtacaggac ggttccgggg ctggagcagg
    17101 tgaaaattgt gagaaacgcc tatgctattg aatatgactg cattaattcc cgccagctga
    17161 aggcaactct ggagtttaag gccgtggaag gcctgttcag cggcggccag tttaacggca
    17221 gttccggtta tgaggaggcg gcggttcagg gctttatggc aggcgtaaat gcggccagaa
    17281 agcttatggg gaaggaagcg gttgtcctgg atcgctcgca ggcttatatc ggcgttttaa
    17341 ttgacgatct ggtgaccaaa gagagccacg agccctaccg catgatgact tccagagcag
    17401 agtacagact gcttctcaga caggacaatg cagatctgag gctttccggc attggacatg
    17461 agattgggct cattgacgac gagaggtatg agcgtgtggt gagaaaggaa cgccagatca
    17521 gagaagaagt ggagcgtctg aaccagcttc cagtgggagc caacagccag gtacaggagt
    17581 gtctgagaaa atatggaagc acagagctta aatcgggcgc tactatggct gagctgatcc
    17641 gcaggccgga gctgagctat gaggcggtaa aggaaatcga cccgaagcgc ccggatctgg
    17701 actgggatgt ggcagagcag gtgaatatca acattaaata cgaggggtat atccgcaggc
    17761 agctgcagca ggtggctcag tttaagaagc tggagagcag aaaattagac gagcattttg
    17821 actattcttc tgtcaagagc ctcagaaagg aagcagttca gaagctaaat ctctacaagc
    17881 cgatgaatat cggacaggcg tcgaggattt caggcgtttc tccggcagat atttccgtac
    17941 ttctcgtcca tttggagcag atgaagcatc agaagggcag ggagtaagtg ttataagctc
    18001 gggagagaaa acgggaagca gaaaaacaga aaagaataca ggaagagcaa aaaaataaac
    18061 gaatataaga atataagaat agaagagtag aagatataga agaacaaagc aatgcagaag
    18121 agagcataga aaaagaagca aaccaatgga gggcctatga gagaagattt caaacagcag
    18181 atggaagagg agctgaaata cgtggatgtg actctgacag acaggcagat agagcagttg
    18241 tacagatatt atgagctttt aaacgagtgg aatcaggtga tgaatctgac tgcgattacg
    18301 gagatgaagg
//
LOCUS       DBMDUW010000049        17960 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1847_length_17960_cov_2.738563, whole genome shotgun sequence.
ACCESSION   DBMDUW010000049 DBMDUW010000000
VERSION     DBMDUW010000049.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 17960)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 17960)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17960
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1847_length_17960_cov_2.738563"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..918)
                     /locus_tag="ACZPCR_09250"
     CDS             complement(<1..918)
                     /locus_tag="ACZPCR_09250"
                     /inference="COORDINATES: protein motif:HMM:NF023568.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HIR1231098.1"
                     /translation="MKLEFYIPSSRAGTRLHGIQWIPDGPVTASLQLCHGMIEHVGRY
                     SELAEYLCRRGIAAAGCDHLGHGRTSNPEDWGFFDEKEGEFRVLEDIQITADYLKRQY
                     PSVPHFILGHSMGSFFLRCYMADKDREIDGALLLGTGGQGFLLAKAGCLLTEAVSAFR
                     GTRYRSRLLHQLLIGRFGRMTDKNGDSHCWLSREEEQVRAYTEDPLNQFIFTSSACRD
                     FMKIIAQAGQRKTLENTRKTLPVFLMSGAQDPVGEKGKGVKRVYRALKQAGLSDVSLK
                     LYPKARHELLHETNREEVLQDIETWIRERI"
     gene            complement(1093..4626)
                     /gene="nifJ"
                     /locus_tag="ACZPCR_09255"
     CDS             complement(1093..4626)
                     /gene="nifJ"
                     /locus_tag="ACZPCR_09255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HIR1231099.1"
                     /translation="MARKMKTMDGNHAAAHASYAFTDVAAIYPITPSSPMAEATDEWA
                     TDGRTNIFGQEVQITEMQSEAGAAGAVHGSLVAGALTTTYTASQGLLLMIPNLYKIAG
                     EQLPGVFNVSARAVASHALNIFGDHSDIYACRQTGCAMLCESSVQEVMDLTPVAHLAA
                     IKGKVPFINFFDGFRTSHEIQKIETWDYEDLKDMADMDAIDAFRKNALNPNHPCQKGS
                     AQNPDIFFQAREACNPYYNALPAIVEEYMNKVNEKLGTDYKLFNYYGAPDAEHVIVAM
                     GSVNDTIEETIDYLLKQGQKVGVVKVRLYRPFCTEAFINAIPETVKKISVLDRTKEPG
                     SLGEPLYLDVVAALRGSKFNDVEIFTGRYGLGSKDTTPAQIVAVYNNTEKPVFTIGIV
                     DDVTNLSLELGAPLVTTPEGTINCKFWGLGADGTVGANKNSIKIIGDNTDMYAQAYFD
                     YDSKKSGGITMSHLRFGHSPIKSTYLIRRANFVACHNPAYVRKYNMVQELVDGGTFLL
                     NCPWDMEGLEKHLPGQVKKYIADHNIKFYTIDGVKLGIETGMGPTRINTILQSAFFKL
                     ADIIPADKANELMKAAAKATYGRKGEDVVMKNWAAIDAGAQHVVEIQVPESWKNCEDE
                     GLDMTHAESGREDVVKFVNTVQAAVNAQEGNNLPVSAFVDYVDGSTPSGSSAYEKRGI
                     AVNVPQWNPDNCIQCNFCSYVCPHAVIRPIPMTEDELAKAPEGTKAVDMTGMPQYKFV
                     MTVSALDCTGCGSCANVCPGKKGEKALTMVPLDTVLGEQKTFDYGQTIDIKEDVIAKF
                     KETTVKGSQFKQPLLEFSGACAGCGETPYAKLITQLFGDRMYIANATGCSSIWGNSSP
                     STPYTVNKKGQGPAWDNSLFEDNAEFGYGMLLAQNAIRNGLKDKVESIAASAEASEEV
                     KAACKEWLDTYTVGALNGAATDKMVAALEGIDCPVCKDVVKNKDFLGKKSQWIFGGDG
                     WAYDIGFGGVDHVLASGKDINIMVFDTEVYSNTGGQSSKATPTGAVAQFAAGGKDVKK
                     KDLASIAMSYGYVYVAQISMGADYNQTVKALAEAEAYPGPSLIIAYAPCINHGIKKGM
                     SKAQTEEKLAVECGYWHNFRFNPAAEKKFSLDSKAPTGDYQEFLKGEVRYASLALKNP
                     ERAKDLAAKNEEEAKARYSYLTRLVTLYGND"
     gene            complement(4946..6724)
                     /locus_tag="ACZPCR_09260"
     CDS             complement(4946..6724)
                     /locus_tag="ACZPCR_09260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004462352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HIR1231100.1"
                     /translation="MSEFNRNPSRGRTSNTGSRRTSPSRSGRSGSGRSSSRNHSGHSE
                     YGKSNYSYSARNMHNRRRRRNRDITQWVVYGVALIVVILAVVLLFKGCKGGGDALEST
                     EESIAGEAADGGITVDGISIDGMTQEEARETILEKYGWDMKVTYNDKTASVNNLMEDR
                     VDELLEEIYGGSTETAFEVNTDNMLDAAKAEASLIAGNWSMVAKNGGISGYNKETGKF
                     TFTEGTNGAVIDQDKLAESIVAAIAAKDYKAQIEAQVKEVEPGLTAAQLEAKYTTIAT
                     YTTTATNNKARNQNLKLSTQALNGTIVNPGQEFSFNETTGPRSTEKGYQPATAYLNGE
                     IVQEPGGGVCQVSSTLYNAVVFAGLKSTERHAHSYEPSYVTPGEDAAVSYGGPDFKFV
                     NNSDYPIAIKASFSDQKVTCSIYGIPVLDEGVKVRMESEKTAELDPPAPTYEEDQTLQ
                     PDEEKTVKNATPGSRWSTALVTYKDEKEIERIDFHNSVYRGKAAIIKRNTSGVVVTTA
                     SPTQSETAAAASTEAAGEASAASTEAAPGPSGPAEGGPSGEGQETQAAGSQSPDGGEA
                     QPPAENPVVPAAPGPDSPADGNSPGN"
     gene            6942..7826
                     /locus_tag="ACZPCR_09265"
     CDS             6942..7826
                     /locus_tag="ACZPCR_09265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007858572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HIR1231101.1"
                     /translation="MSYIDLHVHSCASDGTMTPEEVVDCAARAGLSAIALTDHDTTAG
                     VSRALEAEKKRREAGLPTPAVIPGTEISCSWNRDGKETEIHMLGLFLPPGNSGVQKFL
                     DDMISARDARNREILRRLAADGIVLSEEDLTEGNEDTVITRAHFASALIKKGVVSTAD
                     QAFKKYLASGGRYCPPKQTVKPQEAVSLILKAGGFPVLAHPMRYHLSWKEVETLTSDL
                     TAAGLQGLEVYYSSHTAEQSRKLRELCRRLHLLPTGGSDFHGAKKPDIHIGTGYGGLR
                     VSELLLEDILAFRRSQGL"
     gene            complement(7823..9376)
                     /gene="cobA"
                     /locus_tag="ACZPCR_09270"
     CDS             complement(7823..9376)
                     /gene="cobA"
                     /locus_tag="ACZPCR_09270"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004851 - uroporphyrin-III
                     C-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0019354 - siroheme biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HIR1231102.1"
                     /translation="MKTEIKKGKVWLVGAGPGDAGLLTLRGREVLEAAQSVVYDALVG
                     DGILGWIPEGASQIYVGKRGGSHTKSQSEINQILVEEASKGRRVVRLKGGDPFVFGRG
                     SEEAQVLREHKIPFEVVPGVTSAVAVPAYCGIPVTHRGIAPSFHVITGHRKNGEPAEM
                     DYAAMVREGGTLIFLMGVTSAEHICQELIRSGMDKDTPAALLERGTTAGQRKVISTVE
                     RLWEDGKKAGIKPPAIIAVGEVCSLSDTCGWLEEKPLFGQKVLVTRPRRRSSGMARRL
                     REAGAEVVELPSAEPKLVQDKEEVQDLRETVSQIGRFQWAVFTSPSGVELFFEFMKRE
                     KLDLRLLMGLRFAVIGEGTRRALQSYGLFADYMPERYYARDLGKGLAETLLEEAQGKR
                     PETALLLRARKASDALTEELLKAGIPFEEKTLYDTVLPDASPQAERVKELLKKQDFSF
                     VTFTSASTVEGFLNLLNPDAEELSGFTAVCIGEETRRAASAAGMKTIVSDKPSMDSMA
                     ECMERFAAR"
     gene            complement(9373..10281)
                     /gene="hemC"
                     /locus_tag="ACZPCR_09275"
     CDS             complement(9373..10281)
                     /gene="hemC"
                     /locus_tag="ACZPCR_09275"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006567063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004418 - hydroxymethylbilane synthase
                     activity [Evidence IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HIR1231103.1"
                     /translation="MNGNMIRVGSRESLLAVRQSELIMEQICQANPGVRTELVTMKTT
                     GDKILDQALNQIGGKGLFVKELDRALLDGRIDISVHSLKDMPMEIPEELPVLAWSCRE
                     DKRDVLILRKGLSRLPEKPVIGTGSSRRIIQAAKLYPKAEFKGIRGNIHTRLRKLDAG
                     EYDALILAAAGIRRMGLEDRISRFFSVEEMIPAAGQGTLAVQGRGEAMRAFLEKINSR
                     ESEIMAEAERSFVRTLDGGCSSPVAACASVEKDTLVLRGLYYDEAEKRAVTGTMRGEI
                     EKAGDLGYLLAVKLKAQGKSKGECGE"
     gene            complement(10271..10798)
                     /locus_tag="ACZPCR_09280"
     CDS             complement(10271..10798)
                     /locus_tag="ACZPCR_09280"
                     /EC_number="1.3.1.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_function: GO:0043115 - precorrin-2 dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0019354 - siroheme biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-2 dehydrogenase/sirohydrochlorin
                     ferrochelatase family protein"
                     /protein_id="HIR1231104.1"
                     /translation="MFVDLEGKHVLAVGAGTIGSRRILTLLKFGAQVTAVDPDGRKLK
                     EMEGWNGLSWIREPYEAYRTRLLEKAPDFFMVLTATGNRETDLLAVSDGRRMGAFVNA
                     AADRSLSDFYFPGIACAGSVTAGVTTGGEDHRLAKRACEEVRAFLTEWEESWREQARI
                     ADKTEKKEESRADER"
     gene            10956..11210
                     /locus_tag="ACZPCR_09285"
     CDS             10956..11210
                     /locus_tag="ACZPCR_09285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013272381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231105.1"
                     /translation="MEEVFRAIEDKIRETGYDGLIDGETFYDEICDEIEDKEVGSYLF
                     MSKRDNGDIFEYKVDVMEDQFNLSYVTITSGDRSFHADFD"
     gene            complement(11304..12533)
                     /locus_tag="ACZPCR_09290"
     CDS             complement(11304..12533)
                     /locus_tag="ACZPCR_09290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009263806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HIR1231106.1"
                     /translation="MELNKDNMKRAMVLILYTVVILALAFHMEYVAAFFKAAFRLLFP
                     FLAGAAIAFILNVPMRFIENRILGGVLKMKEDSRLKRPASLLLAIFSVLVIMAVVVLV
                     VVPELTSTLMGLKRLVPAFFENMQIQAERVFAQYPEIVEYINSIEVDWKTLMEDVAAF
                     VTVGAGSILSSTVTAAVSIASGLTTLSISFIFSLYILLQKETLSRQFKRLFYAYFPEK
                     AVDRGLDILRMTERIFSKFLTGQCAEAVILGTMFFITLTVLRLPFALLIGVLIAFTAL
                     IPIFGAFIGCAVGIFLMLMVSPMQALWFTIIFFVLQQIEGNLIYPHVVGGSVGLPSIW
                     VLAAVSLGGSMLGIMGMLVFIPLCSVAYALIKEDVGIQLKEKKIERAKWTSAREQKAQ
                     EKQEKDLGTPSEAEHKN"
     gene            complement(12542..13717)
                     /locus_tag="ACZPCR_09295"
     CDS             complement(12542..13717)
                     /locus_tag="ACZPCR_09295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008398475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA deacylase
                     activity [Evidence IEA];
                     GO_function: GO:0002196 - Ser-tRNA(Ala) deacylase activity
                     [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA editing protein"
                     /protein_id="HIR1231107.1"
                     /translation="MEKLFYEEPYLRVFTARVVSCLPVKRGFEIELDRTAFYPEGGGQ
                     PSDTGTLGEAHVLDVQERDGRIVHLTDLALEEGAAVQGEINWEERFSNMQQHSGEHIV
                     SGLIHRVFGYDNVGFHMGTEEMTIDLNGPMTWEQLMEIERQANQAVWDNLPLHIFYPP
                     EEELSQLDYRSKKELTGQVRIVEIPGTDVCACCGTHVACTGEIGLIKFLSMINYKGGV
                     RISMLCGKKALLACERRVEQASEISALLSAKVEEIVEAVRRQKEELSEEKAAGIALTR
                     QLMDLKSDSYPDSDKVLAVFEEPFSPVQVRQFSNLLMEKGKGAVTVVFGGGKDGYSYA
                     AASRTQDMKAFSQRLNQALNGRGGGSAQMAQGSVKASREEVTAWFSELTGTENSEIE"
     gene            13910..14155
                     /locus_tag="ACZPCR_09300"
     CDS             13910..14155
                     /locus_tag="ACZPCR_09300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004462337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231108.1"
                     /translation="MSDLSATNCGCGCEAAGGGNNLIFLILILICCGGCGGGFCCEHN
                     GCGGGCGGFGGGCECLIWIILLCCCCGGGGGNGGFCC"
     gene            complement(14254..14907)
                     /locus_tag="ACZPCR_09305"
     CDS             complement(14254..14907)
                     /locus_tag="ACZPCR_09305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004844294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-8X methylmutase"
                     /protein_id="HIR1231109.1"
                     /translation="MKTELEQILPEKIEERSFEIISEELNALFPEKTFLPGEELILKR
                     VIHTTADFDYAENLIFSEGAVEQALEALKSGAVIITDTNMGKAGINKKSLERLGGEVL
                     CFMADNDVAEKARQKGTTRASASMDKAAELGRDCIIAVGNAPTALVRLFELIQEGRLA
                     PKLIIGVPVGFVNVVQSKELILSLKDIPYIVARGRKGGSNVAAAICNGLIYQLARER"
     gene            complement(14968..16512)
                     /locus_tag="ACZPCR_09310"
     CDS             complement(14968..16512)
                     /locus_tag="ACZPCR_09310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HIR1231110.1"
                     /translation="MAKAIMIQGTMSNAGKSLIAAGLCRIFRQDGFRTAPFKSQNMAL
                     NSYITSEGLEMGRAQVVQAQAAGVLPEAAMNPILLKPANDIGSQVIVMGKPVGTMPAR
                     EYFQYKKKLVPVIREAYEKLDREYDIIVIEGAGSPAEINLKQDDIVNMGMARMAKAPV
                     LLAGDIDRGGVFAQLYGTVMLLEEEERRYVKGLIINKFRGDRTILEPGADMIEKLCQI
                     PVAGIVPYIKADIEDEDSLSSRLSSRAEGALLDIAVIRFPRLSNFTDFNVFSCIDGVA
                     VRYVERTSELAQPDLIILPGTKNTISDLLWMRQNGLEAAVLKASAAGIPILGICGGYQ
                     MMGRRLRDSRGLESGTENTEVRGMGLLETETEFEEEKMRTQVTGTFEKLPGIFSALSG
                     KRISGYEIHMGRTRCLAGAKSLLKLSECQKREEEEKPERIFEKPDGCFKENVCGTYVH
                     GIFDAPGVAESLAEALLSKKGMSLSSRQNFDYSAYREEQFDLLAGELRKSLDMDLIYK
                     ILREGI"
     gene            complement(16514..17770)
                     /locus_tag="ACZPCR_09315"
     CDS             complement(16514..17770)
                     /locus_tag="ACZPCR_09315"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HIR1231111.1"
                     /translation="MPYLHGGDIYGDASVEIDFSVNTTPLGVPPAVLQAVASCREEIL
                     LYPDSQCRSLRAALSEYWTEQLSFEADEEEDKAKKIQIPASHFICGNGAADLIFGLAE
                     ALKPEKAVLFEPCFSEYETALRLKGCEVITIPLKPEESWLPQPDALRQALEKAGGADL
                     VFLGNPNNPTGMAVPKETIEEMAGLCRRFSAVLAVDECFNGFLENPEVFTAAGLTGQY
                     QNLFLLNAFTKVYGMAGLRLGYGLCSDEELLGKICAVRQPWSVSGIAQKAGIAALKEE
                     EFVRQARKLVKEEREFLTEELQNLGFTVYPSMVNYLLFSLPKFSCGQSSKQYIKKKEN
                     LEYPKSFELKEFLKKKKILIRSCADYRGLDSSFYRIAVKTRSENRKLLQELKAWKNCI
                     QKNGRSRQDKEQSAGQKAEQAHQGGM"
BASE COUNT         4034 a         5076 c         4054 g         4796 t
ORIGIN      
        1 aatcctctcc cggatccatg tttcaatatc ctgcaatacc tcctctctgt tcgtctcatg
       61 cagcagctca tggcgggcct tagggtacag cttcaaagac acatctgaaa gacctgcctg
      121 tttaagagct ctatacacgc gttttacgcc ctttcccttt tctcctacag ggtcctgagc
      181 ccctgacatc agaaaaaccg gcagtgtttt ccgtgtattt tccagagttt ttctctgtcc
      241 tgcctgcgct atgattttca tgaaatcacg gcacgcgctg ctggtaaaga taaactggtt
      301 cagtggatcc tctgtgtagg ccctcacctg ttcttcttct ctggaaagcc agcagtggct
      361 gtccccattt ttatctgtca tgcgcccgaa gcgtccaatc agaagctgat gaagcagtct
      421 gcttctgtac cgggttcccc tgaaagctga gacagcttct gtgagcaggc agcctgcctt
      481 tgccaaaaga aatccttgtc cgcccgttcc taaaagcagc gcgccgtcta tctctctgtc
      541 cttatccgcc atatagcatc tgagaaaaaa agaccccata ctgtgcccca gaataaagtg
      601 cggcactgaa ggatactggc gtttcagata atcagcagta atctgaatat cctccagcac
      661 cctgaactct ccctccttct cgtcgaaaaa gccccagtcc tccggattcg acgttctgcc
      721 atggcccaga tgatcacagc cagctgcagc aattccccgt ctgcacaggt attctgccag
      781 ctcgctatag cgccccacat gctcgatcat gccgtgacag agctggagcg acgctgtgac
      841 aggaccgtcc ggaatccact gaatcccatg gagccttgtt ccagccctgc tggatggaat
      901 ataaaattca agcttcatcc tgtcgcgctc ctccttccct atctcctgcc tgccggctgc
      961 ttcttctcta ttgtctcaca aaattctgca ttttgcaaac agaatacaga ataaatccct
     1021 gctttaaaac tttctttaaa ataaagcaag cgggaagcct gcgaacagac ttcccgcaat
     1081 gtttatttct gattagtcgt ttccgtacag agtaacgagt cttgtcaggt aagagtatct
     1141 tgcctttgcc tcttcctcgt tcttagctgc cagatcctta gctctctcag gattcttcag
     1201 ggccagagat gcgtaacgaa cctcgccctt taagaactcc tggtagtctc ctgtcggagc
     1261 cttgctgtct aaggagaact tcttctcagc agccgggttg aagcggaagt tgtgccagta
     1321 accgcactct acagccagct tctcctctgt ctgagctttg ctcatgccct tcttgatacc
     1381 atggttgata catggagcgt aagcgatgat taaggatggt cccggatatg cctcagcctc
     1441 agccagagcc tttacagtct ggttgtagtc agcacccatg gaaatctgag caacgtatac
     1501 atagccgtag ctcatagcga tggaagccag atccttcttc ttcacatctt taccgcctgc
     1561 tgcgaactgt gcaacagcgc ctgtaggagt agccttggag gactgtccgc ctgtgttgga
     1621 gtaaacctct gtatcgaata ccatgatgtt gatgtccttg ccggaagcca gaacgtggtc
     1681 aacaccgccg aatccgatat cgtaagccca tccgtcgccg ccgaagatcc actgggattt
     1741 cttgccgagg aagtccttat tctttacaac gtccttgcat actgggcagt cgataccctc
     1801 taatgcagct accatcttat ctgtagcagc gccgtttaat gcgcctactg tgtaagtatc
     1861 aagccactcc ttgcatgcag ccttaacttc ctcggaagcc tcagcgcttg cagcgatgct
     1921 ctctacctta tcctttaagc cgtttctgat agcgttctga gctaataaca taccgtaacc
     1981 aaactcagcg ttatcctcga acagggagtt gtcccaagca ggaccctgtc ccttcttgtt
     2041 tactgtgtaa ggtgtagacg gtgaggagtt gccccagatg gaggaacatc ctgtagcgtt
     2101 tgcaatgtac attctgtcac cgaacagctg tgtgattaac ttagcgtatg gtgtctcgcc
     2161 gcagcctgca catgcgccgg agaactctaa gagaggctgc ttgaactggc ttccctttac
     2221 agttgtctcc ttgaacttag cgataacgtc ttccttgatg tcgattgtct ggccgtaatc
     2281 gaaggtcttc tgctcgccga gaactgtgtc aagcggaacc atagtgaggg ccttctcacc
     2341 tttctttcct gggcagacat ttgcacagga accgcatcct gtacagtcaa gagcagatac
     2401 agtcataacg aacttgtact gcggcatacc tgtcatatcg acagcctttg ttccctccgg
     2461 agccttagca agctcgtcct ctgtcatcgg aatcggacgg ataactgcgt gcgggcagac
     2521 ataggaacag aagttacact ggatacagtt gtctggattc cactgcggaa cattgacagc
     2581 gataccgcgc ttctcgtatg cagaggaacc ggatggtgtg gaaccgtcta cgtaatctac
     2641 gaatgcggat acaggcaggt tgtttccttc ctgagcgttt acagcagcct gaactgtgtt
     2701 gacaaacttc acaacgtcct cacgtccgga ctctgcgtgt gtcatatcga gaccctcgtc
     2761 ctcgcagttc ttccagctct ctggtacttg aatctcaact acatgctgag cacctgcgtc
     2821 gatagcagcc cagttcttca taacaacgtc ctcacccttg cggccgtagg ttgcctttgc
     2881 agcagccttc ataagctcgt ttgccttgtc agccgggatg atgtcagcca gcttgaagaa
     2941 tgcagactga aggattgtgt tgatacgtgt cgggcccatg cctgtctcga tacctaactt
     3001 cacaccgtcg atggtgtaga acttgatatt gtgatcagcg atgtacttct taacctgtcc
     3061 cggtaagtgc ttctcaaggc cttccatatc ccatgggcag tttaacagga atgtaccgcc
     3121 gtcaaccagc tcctgaacca tgttgtactt gcgtacatat gccgggttat ggcatgctac
     3181 gaagtttgca cggcggatca ggtaagtgga cttgatcggg gaatgtccga aacgcaggtg
     3241 ggacattgtg ataccgccgg acttcttgga gtcatagtca aagtaagcct gagcgtacat
     3301 atctgtgtta tcgccgatga tcttgatgga gttcttgtta gcgcctactg taccgtcggc
     3361 tccaagtccc cagaacttgc agttgatagt accctctgga gtagttacga gcggagcgcc
     3421 cagttccaga gaaaggtttg taacgtcgtc cacgataccg attgtgaata ccggcttctc
     3481 tgtgttgttg tatacagcga cgatctgtgc cggagtagta tccttggaac ctaatccgta
     3541 acgtcctgtg aagatctcaa cgtcgttgaa cttgctgcct cttaaagctg ccactacgtc
     3601 taagtataac ggctcgccga gagaacctgg ctcttttgtt ctgtcgagaa cggaaatctt
     3661 cttaactgtc tcaggaattg cattgataaa tgcctctgtg cagaatggtc tgtacagacg
     3721 aaccttcaca acgccgacct tctgtccctg ctttaacagg tagtcgatag tctcctcgat
     3781 ggtgtcgttt acagaaccca tggcaacgat tacgtgctca gcatccggag ctccgtagta
     3841 gttgaacagc ttataatctg ttcccagctt ctcgtttacc ttgttcatgt actcctcaac
     3901 gatagccgga agagcgttgt agtatgggtt gcatgcctct cttgcctgga agaagatatc
     3961 cgggttctga gcggaaccct tctggcatgg gtggttcggg tttaatgcgt tctttctgaa
     4021 tgcgtcgata gcatccatat cagccatgtc cttcagatcc tcgtaatccc atgtctcgat
     4081 cttctggatc tcgtgggatg tacggaagcc gtcgaagaag ttgatgaacg gaacctttcc
     4141 cttgatagct gccagatggg caactggagt taagtccata acctcctgaa cactggactc
     4201 gcagagcata gcgcatccag tctgacgaca ggcataaata tcagagtgat caccgaaaat
     4261 atttaatgcg tgggaagcaa cggcacgtgc ggatacgttg aatacgcctg gaagctgctc
     4321 acctgcgatc ttgtacaggt tcgggatcat cagtaaaagt ccctgagaag ctgtgtaggt
     4381 agtagttaaa gcgcctgcta ccagagaacc gtgtacagcg cctgctgcac cagcctcaga
     4441 ctgcatctct gtaatctgta cttcctgacc gaagatattg gttcttccgt ctgtcgccca
     4501 ctcatctgtg gcttccgcca taggagaaga tggggtgata ggatagatag ctgcaacgtc
     4561 tgtaaacgcg taggaagcgt gagctgctgc gtggtttcca tccatggtct tcatttttct
     4621 tgccattgaa tattcctcct ataaatataa atataaaaat atttattgag atagttccct
     4681 tgcgggaaat ttacctgtta catattatac caactttttg ttaaaatgca aacgaaaaag
     4741 gacgtttccc gcgtacttaa ttagaaacaa tctgtagaaa gaagacgaat ctcgctcttc
     4801 ctgtttctgg tattacctgg aaacaccaga aaaaacagag aaaggcagat cccgaaacga
     4861 atctgcctct tcactggtgc tgttattctc ttttttgttt gaaaaatttc ttttttactg
     4921 acaactttat aacaaacttt tccttttaat ttcccgggct gtttccatcg gctggagaat
     4981 ctggtcccgg agccgccgga acaactgggt tctcggcagg cggctgcgct tctcctccgt
     5041 ctggagactg gctgcctgcc gcctgggttt cctgtccttc tccagacgga ccgccctctg
     5101 cagggccgct cggtcccgga gccgcctctg tggaagctgc tgaagcttcg cctgctgcct
     5161 ctgtggaagc tgccgccgct gtctcagatt gagtcggaga cgccgtcgta accaccacgc
     5221 cggaggtatt tcgcttgata atggccgctt ttcctctgta tacgctgttg tggaaatcaa
     5281 ttcgctcgat ttccttttca tccttgtagg ttaccagagc cgtactccat ctgcttcccg
     5341 gagtggcatt ctttaccgtc ttctcctcgt caggctgaag cgtctgatcc tcctcgtagg
     5401 ttggagccgg cggatctaat tccgccgttt tctcagattc catgcggacc tttactccct
     5461 catccagtac gggaatgccg tagatggagc aggtgacttt ctgatccgag aagctggcct
     5521 taatagcaat cggatagtca gagttattga cgaacttaaa atccgggccc ccgtagctga
     5581 ctgccgcgtc ctcgccaggc gttacatagg agggctcata gctgtgggca tggcgctccg
     5641 tactctttaa tccggcaaac acaactgcat tgtacagggt ggaggatacc tggcacacgc
     5701 cgccgcccgg ctcctggaca atctcgccgt ttaagtacgc ggtcgccggc tgatatccct
     5761 tctccgtaga acgaggtcct gtcgtttcat taaaggaaaa ctcctggccc gggttcacaa
     5821 tcgttccatt taaagcctgg gtggacagct tcagattctg gtttctggct ttattattcg
     5881 tagctgtcgt cgtgtatgtg gcaatcgtcg tatacttggc ttccagctgg gccgccgtca
     5941 gccccggttc tacttccttg acctgggctt ctatctgcgc tttataatcc ttcgctgcaa
     6001 tagcagccac aattgattcc gccaatttgt cctggtcaat gactgccccg ttcgttcctt
     6061 ctgtgaaggt gaacttgcct gtttctttat tataaccaga gataccgccg ttcttggcca
     6121 ccatgctcca gtttcctgca atcagagagg cctcggcctt agccgcatcc agcatgttgt
     6181 ctgtgttgac ctcaaacgct gtctctgtgc ttccgccgta aatctcctct aaaagctcat
     6241 ctacccgatc ttccatcagg ttattgacag aggccgtctt atcgttgtag gtaactttca
     6301 tatcccagcc gtatttctcc aggatcgtct cgcgggcctc ttcctgcgtc atgccgtcga
     6361 tggaaatgcc gtctaccgtg ataccgccgt ccgccgcttc gcccgcgatg gattcctctg
     6421 tgctttcaag ggcgtccccg cctcccttgc agcctttaaa aagaagcacc acagccagta
     6481 tcactactat cagcgctacg ccgtaaacca cccactgagt gatatccctg ttcctgcgcc
     6541 gcctgcggtt atgcatattt ctggcgctgt aggagtaatt tgactttccg tattcggagt
     6601 gcccggaatg atttctagaa gaggatcggc cggatccgct ccttcctgac cgggagggag
     6661 acgttcttct gctccctgta tttgacgtcc ttcctctgga cgggtttctg ttaaattcgc
     6721 tcatgcttat cacctaaaat cctagtatag tattctaggg acaagtatag cacaatttgt
     6781 caaaaatgaa atgacttatt tcttaaaaat tttatttctg tcgaaatttt acccgaagcc
     6841 tgttttgtgg tatgatacat tgtatctttt tactaagggt tattacagaa ccgttacagc
     6901 agttttaatt ctattaatat ttttcaggag gtatcctttt tatgagttat attgatcttc
     6961 acgtacattc ctgcgcctct gacggaacca tgacgccgga ggaggtggtg gactgcgccg
     7021 ccagggcagg attatcggcc atcgctctca cagatcacga tacgacagcc ggggtttcaa
     7081 gagccctgga ggcagagaaa aaaagacggg aggccggtct tcccacgccg gcggtgattc
     7141 cgggcacgga aatttcctgc agctggaacc gcgatgggaa ggagacggaa atacacatgt
     7201 taggattatt tcttccaccg ggaaacagcg gggttcagaa atttttagac gatatgatct
     7261 cagccagaga tgcccgcaac cgcgagattc tgcgccgcct tgcggcagac ggcatcgttc
     7321 tgtctgagga agatttgaca gagggaaacg aggatacggt aatcaccaga gcgcattttg
     7381 cctccgctct cataaaaaag ggggtcgtct ccacggcaga tcaggcgttt aaaaaatacc
     7441 tggcttccgg cggcagatac tgccctccca agcagacagt aaaaccgcag gaggctgttt
     7501 ctctcatttt aaaagccgga ggctttcccg tcctggccca cccgatgcgt taccatctgt
     7561 cctggaagga ggtggaaacc ctgacttcag atctgacggc ggcgggactt cagggactgg
     7621 aggtctacta ctcctcccac acggcggagc agagcagaaa gctccgggag ctgtgccgcc
     7681 gcctgcatct gcttcccaca ggaggctctg actttcatgg agccaaaaag ccggatatcc
     7741 atataggaac cggctatggc ggtctcagag tttctgagct tcttctggaa gatatcctgg
     7801 ccttccgaag aagccaggga ctctaacggg ccgcgaaacg ttccatgcac tccgccatgc
     7861 tgtccatgga aggtttgtct gagacaatgg ttttcattcc tgccgcactg gccgcccgcc
     7921 ttgtctcctc gccgatgcag actgccgtaa atccggaaag ctcctctgca tctggattta
     7981 aaagatttaa aaatccttct accgtcgacg cgctggtaaa ggttacaaaa gaaaaatcct
     8041 gttttttcaa aagctccttt accctctctg cctgcggtga ggcgtctggc aggaccgtat
     8101 cgtaaagggt tttttcctca aatggaattc ctgcctttaa aagctcttct gtgagagcgt
     8161 ccgaggcttt ccgggcccgg aggagaagcg ccgtttcagg gcgttttccc tgagcttctt
     8221 ctaagagcgt ctctgccagg ccttttccca gatccctggc atagtagcgt tctggcatat
     8281 agtcggcaaa cagaccgtat gactgaagag cccgtctggt gccttcccca atcacggcaa
     8341 agcgcagtcc catcaggagc cgcagatcca gcttctcccg cttcataaat tcaaaaaaca
     8401 gctccactcc gctggggctg gtaaagactg cccactgaaa ccgtccaatt tgagaaaccg
     8461 tttctctcaa atcctgaact tcctctttat cctgcaccag ctttggctcg gctgaaggaa
     8521 gctccaccac ctcggcgcct gcttccctga gtctcctggc cataccggac gagcggcgtc
     8581 tgggtctcgt gacaagcacc ttctgtccaa agagaggctt ttcttccagc cagccgcagg
     8641 tatcggaaag actgcacacc tctcccaccg caatgatggc cggaggtttg atgccagcct
     8701 tctttccgtc ctcccacaga cgttctactg tggaaattac ctttctctgt ccagcggttg
     8761 ttccccgttc cagcagggct gccggagtat ccttgtccat gccgcttctg atcagctcct
     8821 ggcagatatg ttccgccgag gtcactccca taaggaaaat gagagtcccg ccttcccgca
     8881 ccatggccgc ataatccatt tcagccggct cgccgttttt cctgtggcct gtaatcacat
     8941 ggaaggacgg agcgattcct ctgtgggtca cagggatccc gcagtaagcc ggaaccgcta
     9001 ctgctgaggt gactccggga actacctcaa aggggatttt gtgttctctc agaacctggg
     9061 cttcctcgct tcctctgccg aatacaaagg gatcgccgcc ctttaagcgc actactctcc
     9121 tgcctttaga agcctcctcc accagaatct ggttaatctc tgactggctc tttgtgtggg
     9181 agccgccccg ctttcccaca taaatctgac tggccccttc gggaatccag ccgaggatcc
     9241 cgtctcctac cagcgcatcg taaacaacag actgagccgc ctccagaacc tctctgcccc
     9301 ggagagtcag cagtcccgcg tctcccggtc cggctcccac cagccacact tttccttttt
     9361 ttatctctgt tttcattctc cgcattctcc cttgcttttc ccctgtgcct tcaatttcac
     9421 agccagaaga tatcccagat ctccggcctt ttctatctct ccccgcatcg ttcccgttac
     9481 cgcccgtttc tccgcttcat catagtaaag tccccgcaga acgagcgtgt ctttctcaac
     9541 agaagcgcag gcggccacag gagaggaaca ccctccgtct aatgtcctta cgaagcttct
     9601 ctccgcctct gccatgattt ctgattctct cgaatttatc ttttccagaa aggccctcat
     9661 ggcctctcct cttccctgga cggccagagt cccctgcccg gcagctggaa tcatctcttc
     9721 cactgagaaa aaacggctga tccgatcttc taatcccatt ctgcggattc cggcagccgc
     9781 caggattaaa gcgtcgtact ccccggcgtc cagttttcgc aggcgggtat ggatatttcc
     9841 ccggatcccc ttaaattctg ccttaggata gagcttcgcc gcctggatga ttctcctgct
     9901 gctgcccgtt ccaatcaccg gcttctcagg aaggcggctg aggcctttcc tcaaaatcag
     9961 cacgtccctt ttatcctccc tgcaggacca tgccagaacc ggaagctcct ctggaatttc
    10021 catgggcata tcttttaagc tgtgaacgga aatgtcaatt cttccgtcta acagggctct
    10081 gtccagctcc tttacaaata aaccctttcc gccaatctga ttcagcgcct gatctaagat
    10141 tttgtcaccg gtagttttca tggtcacaag ctctgtcctg acgcctggat tcgcctggca
    10201 gatctgctcc ataataagtt ccgactggcg gaccgctaaa aggctttccc tgcttcctac
    10261 ccgtatcata ttaccgttca tcggctctgc tctcctcttt cttctctgtc ttatctgcaa
    10321 tccgtgcctg ttctctccag ctttcttccc attccgtcag aaaagctctc acctcttcgc
    10381 aggcccgttt tgccagccgg tggtcttctc cccctgtggt cactcctgcc gtcacggagc
    10441 cggcgcaggc aatcccgggg aaataaaaat ctgacagaga ccgatctgcg gccgcgttca
    10501 caaaagctcc catccgcctt ccatctgaaa ctgccagcaa atccgtctcc ctgtttccag
    10561 ttgccgtaag caccatgaaa aaatcgggag ccttttccag gagccgcgtt ctgtacgcct
    10621 catacggttc ccggatccag gacaatccgt tccatccttc catctctttc agcttccggc
    10681 cgtccggatc caccgctgtc acctgggctc cgaattttaa cagtgttaaa atcctcctgc
    10741 ttcctatggt tccggccccc actgccaaaa cgtgtttccc ctcaagatct acaaacattg
    10801 gaaaatatga catgcccgcc tccaattctt cttttcacat tcctcttatt atacacaaaa
    10861 tcacgttttt ttcaaataaa tttatctggc gattgacggc ttgggatttg gcctgtatac
    10921 tggaggaaaa catcggcaga gaaaggaagg gctctatgga agaagtgttc cgggcaatcg
    10981 aggataaaat cagagaaaca ggatatgacg gtctcataga cggagagaca ttttacgatg
    11041 aaatctgtga tgaaatcgaa gacaaggagg tcggctccta tctctttatg tctaaaaggg
    11101 acaacggaga tatctttgag tataaggtag atgtgatgga ggatcagttt aatctctctt
    11161 acgtcactat cacctcagga gaccgcagct ttcacgcaga tttcgactaa acgttgtcct
    11221 ttgcatcatg cagcggaaaa caaaactacc cgcaggagaa aacggatacg ctatacattc
    11281 cgtctcccct gcgggctttt ttattaattc ttatgttctg cttctgaagg cgtacccagg
    11341 tctttctctt gcttctcctg cgctttctgt tctcttgcag acgtccattt tgcacgttct
    11401 attttctttt cctttaactg gatccccaca tcctccttta tcagggcata ggccacagag
    11461 cagagtggaa tgaaaaccag cattcccata attcccagca tactgccgcc taaagacacg
    11521 gcggccagca cccagataga agggaggccc accgaaccgc ctaccacgtg aggataaatg
    11581 agatttcctt ctatctgctg gagcacgaag aaaataatgg taaaccagag ggcctgcata
    11641 gggctcacca tgagcatcag aaagattccc accgcgcagc cgatgaaggc tccaaaaata
    11701 ggaatcagcg ccgtaaacgc aatcaacact ccgattaaaa gggcaaacgg aagcctgaga
    11761 accgtcagcg ttataaaaaa catagtgccc agaatgaccg cttccgcaca ctgccctgtg
    11821 agaaatttag aaaaaatccg ctccgtcatc cgcagaatat ccagcccccg atccactgcc
    11881 ttctccggaa aatacgcgta gaacaggcgc ttaaactgcc tggacagagt ttccttctga
    11941 agcaggatat agagggaaaa gataaaggaa atactgagtg tcgtaagtcc gctggcaatg
    12001 gagacagcag ctgttacggt agatgataaa atacttcccg caccgactgt cacaaacgcg
    12061 gccacgtcct ccatcagagt tttccagtcc acctcaatac tgttaatgta ctctacaatt
    12121 tccggatact gggcgaatac ccgctccgcc tgaatctgca tattttcaaa aaaggcggga
    12181 accagacgtt ttaatcccat cagcgtgctg gtcagctccg gaacgactac caaaacgacc
    12241 acagccatga tgacgagtac agaaaaaatg gccagcagaa ggctggcagg acgtttcagg
    12301 cggctgtctt ccttcatttt taaaactccg cccaggattc tgttttcaat aaaacgcatc
    12361 ggcacattta aaataaaagc gatagcggct ccggccagaa atggaaacag cagccggaaa
    12421 gctgccttaa aaaaagctgc cacatattcc atgtgaaagg ccagggccag aatgactacc
    12481 gtgtagagta tcagaaccat cgcccgtttc atattgtctt tatttaactc cataactccc
    12541 cttattctat ctcgctgttt tctgtcccag taagctctga aaaccaggct gttacctctt
    12601 ccctggacgc ttttacgctt ccctgggcca tctgagcgct tccgcctccc cggccgttta
    12661 acgcctgatt gagtctctgg ctgaacgcct tcatatcctg tgttctgctg gcagctgcat
    12721 aggaatatcc gtcctttccg ccgccgaata cgactgtaac cgctcccttt cccttttcca
    12781 tgagaaggtt gctgaactga cgcacctgaa ccggcgaaaa gggttcctca aagacggcta
    12841 aaaccttgtc agaatctgga taactgtcag atttcagatc catcagctgt ctggtcaggg
    12901 caattcctgc cgccttctcc tcagaaagct cttccttctg ccgccttaca gcctccacaa
    12961 tctcttccac ctttgccgac agcagggcgg agatctccga cgcctgctcc actcttctct
    13021 cgcaggctaa aagagccttt ttgccgcaga gcatggaaat acgcacgccg cctttgtagt
    13081 taatcatgga cagaaattta atcagcccaa tctctcccgt gcaggccaca tgagttccgc
    13141 agcaggcgca cacgtccgtc cctggaattt ctacaatgcg cacctggccg gtcagctcct
    13201 tcttgcttct gtaatcaagc tgtgaaagct cttcctccgg cggataaaag atatgcagag
    13261 gaagattatc ccagaccgcc tggttggcct gcctttcaat ttccatcagc tgttcccatg
    13321 tcatagggcc gtttaagtca atggtcattt cctccgttcc catgtgaaag cccacgttgt
    13381 cgtaaccgaa gactctgtga atcagccctg acacaatatg ctctccagaa tgctgctgca
    13441 tgttggaaaa gcgttcctcc cagttgatct ctccctgcac cgcagcgccc tcttccagag
    13501 ccagatccgt gaggtgaacg attcttccgt ctctctcctg tacgtccagc acatgggctt
    13561 ctcccagggt tcccgtatca gacggctggc ctcctccctc cggataaaac gctgtcctgt
    13621 caagttctat ctcaaatccc cttttcaccg gcaagcagga aacgaccctg gctgtgaaaa
    13681 cgcgtaaata gggttcctcg taaaataatt tctccatgat ttatgcttca tcctcctgta
    13741 aaaacctgtc tggcctgatt cttataatta tacacagttt ctgccccggt tcaatcaccc
    13801 tgagaggaaa ttttccagat tcttttcatt ttattttcgt tcttgtggaa acagtggcaa
    13861 gccgcccggc atatgatgga gtgtatagaa aatgtcggag gaactgaata tgagcgattt
    13921 atcagcaact aactgcggat gcggatgtga ggcagcagga ggaggaaata acctgatttt
    13981 cctgattctc attctgatct gctgcggcgg atgcggcggc ggcttctgct gtgaacataa
    14041 tggatgcggc ggcgggtgcg gcggttttgg aggcggatgc gaatgcctga tctggattat
    14101 cctgctgtgc tgctgctgtg gcggcggagg cggaaacggc ggcttttgct gctgattgca
    14161 gactgtctga aaacatagcc cacactggct gagcaggagt ccgccgcgca gaaaattgtc
    14221 tttgtgcggc ggacgctggc tctgatgaaa ggcttatctt tctctggcca gctggtaaat
    14281 caggccgttg cagatggccg cggctacgtt gctgccgcct tttctgcccc gggccacaat
    14341 atagggaatg tcttttaagg agagaatcag ctcctttgac tgcaccacat tcacgaatcc
    14401 taccggaacc ccgataatca gcttcggagc cagtctgcct tcctgaatca gctcaaacag
    14461 ccggaccagg gcagtcggcg catttccaac agcgataata cagtcccggc ccagctctgc
    14521 cgccttatcc atgctggcag aggctctggt ggttcccttc tgtctggctt tttctgccac
    14581 atcattgtct gccataaagc agagaacctc tccccccagc cgttccaggc tttttttgtt
    14641 aattccggcc tttcccatat tcgtatccgt gataatcact gccccgcttt tcagcgcttc
    14701 cagcgcctgc tccactgctc cctccgaaaa aatcagattt tcagcgtagt cgaagtctgc
    14761 cgttgtgtgg atgacgcgtt tcaagatcag ctcttctcca ggaagaaatg tcttctcagg
    14821 aaacagcgcg ttcagctcct ctgagataat ctcaaagctt ctctcctcta ttttttcagg
    14881 cagaatctgt tccaactctg ttttcatata cttttatcct ctttctcttg ttttcctgtc
    14941 ctggcatgcc tgccagaagt tctgttccta tattccctcc cggagaattt tataaatcaa
    15001 atccatatcg agacttttcc tcagttcgcc cgccagaagg tcaaactgtt cttcccggta
    15061 tgcgctgtag tcaaagttct gcctgcttga caggctcatt cctttctttg aaaggagagc
    15121 ctctgccaga gattctgcca ctcctggagc gtcaaaaatt ccatgcacat aggttccgca
    15181 aacattctcc ttaaaacagc cgtccggctt ttcaaatatc cgttccggct tttcttcttc
    15241 ctcccgcttc tggcattctg acagcttcag gagggatttt gccccggcca ggcatctggt
    15301 ccgccccata tgaatttcat atccggaaat gcgtttcccg gaaagagcgg aaaagatccc
    15361 tggaagcttt tcaaaggttc ccgtcacctg tgttctcatt ttctcttcct caaattccgt
    15421 ctctgtctcc aaaagcccca ttccgcggac ttctgtgttc tctgttcctg actccagccc
    15481 tctgctgtct ctcaggcgcc ttcccatcat ctgatagccg ccgcagatac cgagtatggg
    15541 aattcctgct gcagacgctt tcagcacagc ggcctccaga ccattctggc gcatccagag
    15601 cagatcggag atggtgtttt ttgtccccgg caggataatc agatccggct gcgccagctc
    15661 tgacgtgcgt tccacatacc ggacagcgac tccgtctatg caggaaaaca cattaaaatc
    15721 agtgaaattg gaaagtctgg gaaaacggat gacagcgata tctaaaagcg ccccctccgc
    15781 tctgctgctc agacggctgc tcagactgtc ctcatcctca atatctgcct ttatatatgg
    15841 aacaattccc gccaccggta tctggcacag cttctcaatc atatcggctc ccggctctaa
    15901 aatcgttctg tcgccgcgga atttattgat aatcagccct ttgacgtacc tgcgctcctc
    15961 ctcttccaga agcatcaccg taccataaag ctgggcgaat acgcctcccc ggtcaatgtc
    16021 gccggccaga agcacagggg cctttgccat cctggccatc cccatattta caatgtcgtc
    16081 ctgcttcaga ttgatttccg ccgggcttcc ggctccctca atcacgatga tgtcgtactc
    16141 ccgatccagc ttttcgtaag cctcccggat tacaggaacc agcttttttt tatactggaa
    16201 atattctctg gcaggcatgg ttcccaccgg ttttcccatg acaatcacct gagaacctat
    16261 atcattggcc ggtttcagaa gaatcgggtt catggcagcc tcaggcagaa cgccggccgc
    16321 ctgggcctgt accacctgag cccggcccat ttccagccct tccgaagtaa tataggaatt
    16381 gagagccatg ttctgagatt taaagggagc cgtccggaaa ccatcctgtc tgaaaatgcg
    16441 gcagagtccg gcagcaatca ggctttttcc cgcgtttgac atggtgccct gtatcataat
    16501 cgcctttgcc attttacatt cctccctgat gcgcctgttc cgctttctgc cctgcgctct
    16561 gctctttgtc ctgccgactc cttccgttct tctgaatgca gttcttccac gccttcagtt
    16621 cctggagaag ctttctgttt tcactccgcg tctttacggc aattctgtaa aaggaagaat
    16681 caaggcctct gtaatcagca caggaacgga ttaaaatttt cttttttttc aaaaattctt
    16741 tcaattcaaa tgattttgga tattccaaat tttctttttt ctttatatat tgttttgaac
    16801 tttgtccaca gctgaacttc ggaagagaaa acagcaggta attgaccata gacggataga
    16861 ccgtaaagcc caggttctga agctcctctg tgagaaattc tctctcctct ttcaccagtt
    16921 ttctggcctg ccgcacaaat tcctcttcct ttaaagccgc gattcctgcc ttctgggcaa
    16981 tccccgacac gctccagggc tgtctcactg cacatatttt tcctaaaagc tcctcgtcag
    17041 aacaaaggcc gtagcccagg cggaggcccg ccatcccgta gaccttggta aatgcattta
    17101 ataggaacag attttgatac tgtcctgtaa ggcctgccgc tgtaaacact tccggatttt
    17161 ccagaaatcc gttaaagcat tcatccaccg ccaggacggc cgaaaaccgg cggcagagcc
    17221 ctgccatttc ctctatggtt tcctttggga cagccatccc ggtgggattg tttggatttc
    17281 caaggaatac cagatctgcg cctcccgcct tttctaaggc ctgtctgaga gcatccggct
    17341 ggggcagcca gctttcctcc ggcttcagag gaatcgttat cacttcgcag ccctttaacc
    17401 gcagagctgt ctcgtactca gaaaagcagg gttcaaacag aaccgctttc tcaggcttta
    17461 aggcttctgc caggccgaaa atcagatcag ccgccccatt tccgcagatg aaatgagacg
    17521 caggaatctg gattttcttt gccttatcct cttcttcatc cgcctcaaag gacagctgtt
    17581 ctgtccagta ttctgacagc gccgctctga gcgagcggca ctggctgtct gggtagagca
    17641 gaatctcctc ccggcaggaa gcaactgcct gaagaacagc aggaggaacg ccaagaggcg
    17701 tagtgttgac tgaaaaatca atctctacgc tggcatcgcc ataaatatct ccaccatgta
    17761 aataaggcat actaaacacc tctatctatc ttatatctgt tttgtaagct tactcatttt
    17821 atcacaaaaa atagaaaaag tctcttaaaa caaattatcc cacagcagaa aagctttgtg
    17881 ctgctgtggg agggtttcat aaaaattgct atttaaattc ccatttctgt ctacgcagac
    17941 tgaatatgcc atttttagtc
//
LOCUS       DBMDUW010000050        17921 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1852_length_17921_cov_3.455724, whole genome shotgun sequence.
ACCESSION   DBMDUW010000050 DBMDUW010000000
VERSION     DBMDUW010000050.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 17921)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 17921)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17921
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1852_length_17921_cov_3.455724"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..872)
                     /locus_tag="ACZPCR_09320"
     CDS             complement(<1..872)
                     /locus_tag="ACZPCR_09320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013274637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HIR1231112.1"
                     /translation="MATITQDMRYRLSLIQYAEKFGVTKAAMKYKTNRQYIYRWKRRY
                     DGSWDSLRELSRRPHSHPNQHTVDEIKLIRHMRRRNPHAGLVVFWVKLRQRGYSRSIS
                     GLYRFLRKQGIMAVHPPNPKYIPKPYEAMDYPGQRIQVDVKFVPSACLKNPQVIGKQF
                     FQYTAIDEYSRWRFVEAFEEHSTYSSAQFVEHLVKAFPCPIECIQTDNGTEFTNRFTS
                     HKEKPTLFQKHLELHGIRHKLIRPFTPRHNGKVERSHRKDNERFYATHLFYSFEDFAA
                     QLKVYNRRDYNNFP"
     gene            1117..2475
                     /locus_tag="ACZPCR_09325"
     CDS             1117..2475
                     /locus_tag="ACZPCR_09325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008395663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1231113.1"
                     /translation="MKQRVSAGRNIDLTEGPVARSMWTFALPLIAGNLLQQFYNVADT
                     LIVGRFLGPGALAAVGSSYTVMTFLTSVILGLCMGSGVLFSMLCGAGDTERMKNSFVQ
                     SFLFIGLVTALVEALSLIFLDPMMGILKIPSDILEETGEYLQVIFMGLMFTFVYNYFA
                     ALLRALGNSVVPLLFLAVSALGNIVLDLVFILKFHMGTAGAAWATILAQFLSALGIGL
                     YVCVKMPHLLPGRRHFYRDRNILKTISRYSILTCAQQSVMNFGILMVQGLVNSYGVTV
                     MAAFAAAVKIDSFAYMPVQDFGNAFSTFIAQNQGAGKTERIRLGLRAAVLSSGLFCLV
                     ISAVIVCFAGPLMTIFISPEETEIIRIGVQYLHIEGACYVGIGCLFLLYGLYRGLGRA
                     GVSVVLTIISLGTRVALAYLLSPVPAIGLLGIWWAVPIGWFLADAAGFWYFWRMGRRK
                     GV"
     gene            2645..3904
                     /locus_tag="ACZPCR_09330"
     CDS             2645..3904
                     /locus_tag="ACZPCR_09330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015541234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1231114.1"
                     /translation="MREARVLEFKETITNTFLKTVSAFSNYGGGTILFGVDDDGTVKG
                     LPDVKQACLDIENKINDSISPQPNYTLEIQNHDQTIKLTVKSGLQKPYLYKSKAYKRN
                     DTATIEVDTLEFSRLILDGKNIRFEELPCKDQELSFKVLRRKLKESIQIETFNQDTLK
                     TLNLYDNVNGFSNAAGLLADKNHFPGIDLVKFGENISVIQRRATFENISVLDEYEKTT
                     AVFRDYYQYEVIQGADRKRVEKIPEAAFREAVANALIHRAWDVDSQIRVSMFDDRIEI
                     VSPGGLPSGITAEEYLSGRLSVLRNRNLANVFYRLGFVEIFGTGITRIKQLYEESLIK
                     PEFEVSENAIKIMLPVFESNVNLTEDEKVIYTLLSKTMLKPISEIAPYAPFGKSKTTK
                     LLKDMEEKGVITVEGKGRGTKYIINWK"
     gene            3926..4162
                     /locus_tag="ACZPCR_09335"
     CDS             3926..4162
                     /locus_tag="ACZPCR_09335"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231115.1"
                     /translation="MSLCCFASIQRESEEEIIYFNAVGMGIEDLAVVTRAYRAAKERG
                     LGVTVNYWAEQKTQREALVPHTFLCHNRRIAENI"
     gene            4183..5202
                     /locus_tag="ACZPCR_09340"
     CDS             4183..5202
                     /locus_tag="ACZPCR_09340"
                     /inference="COORDINATES: protein motif:HMM:NF048703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF7309 domain-containing protein"
                     /protein_id="HIR1231116.1"
                     /translation="MMKQEASLEQWNSLYQAAAAVTKLAPWEDFWNTDLIVIQESRKQ
                     EPLFMSISGRGIHNRGVTMYIGNDGLEDFDLTESTRGEALASFALREQRCLSFKLCDR
                     EDVPQEQRDMIKELGLAFRGRGKWPCFLSWRKAYAPWTLDGEEVQILTEAFCRMEEAV
                     KDARDGAVKVRFERGEFLWRSRDEETGDWRTVSAPIPSGRRKYPLARLRSVDQIEAVK
                     SRPRSINELSMDLFYMNAEVVEEGYDRPFFPRAFLVMEKRTRAVLNMQVLEPEDNEVS
                     AILHFLLNYIMKSGRPRTVYARNPWIFAALTDTCEKCGIPLLSSALEEMEEMVNQLTD
                     AGMEE"
     gene            complement(5252..5953)
                     /locus_tag="ACZPCR_09345"
     CDS             complement(5252..5953)
                     /locus_tag="ACZPCR_09345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007717651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIR1231117.1"
                     /translation="MAEEKILIADDDPAVRRLLIRVVEGSGFQAVTACDGTEAVHLAS
                     RESFALILLDIMMNGNDDGFHAIKRLRESGNTTPIMVLSGRTDDFDTLYGLDIGADDY
                     VSKPFNPVILGGKIKALIRRNQTGKQEKTGIITAGPFSYNTITMELFKNGTPIPLSSR
                     EHVLMRLFLSHPGQVFTKEQLYELVWNHSAVDDNVIMVYISHLRNKIEDQAKNPCYIK
                     TVWGIGYTFSCQDPS"
     gene            6200..7507
                     /locus_tag="ACZPCR_09350"
     CDS             6200..7507
                     /locus_tag="ACZPCR_09350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0046942 - carboxylic acid transport
                     [Evidence IEA];
                     GO_process: GO:1905039 - carboxylic acid transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HIR1231118.1"
                     /translation="MYLALLGFAMIVVFMGLIMAKKLSPFTSLILIPIVFGLLAGYGW
                     DTLEYAMTGIKDVASTFAMMTFAILYFGVMLTAGMFDPMVDKVVSWCKGDPLKVLVGT
                     AVLAAFVSLDGDGTTTVMICCTAMIPIYERLKIKKIYLATLIILQNCIMNLIPWGGPT
                     ARVMSVMNLDAGEILGPLVPGMALSAVYVIGVSYYLGLKERKRLGISRDVENHAVKVE
                     LSEDEKAWKRPKLILFNLALTAGIIVALIMGLASSAILFGVGTAVALLVNYPNQKVQR
                     NVISSIAPDMINVVMMVLGAGVLMGILNGPEDAGMSNAIAEFLVAVIPESLAKYFAIV
                     IAVISAPGTYLLNNDAFYYGVLPPLAATAQAYGFTDLNIGFAALMGQAFHFLSPLVPF
                     IYLLMDKTEITLAQYQGYIFKWCIGIFVIFMAMGLVTGYLPIL"
     gene            7637..9487
                     /locus_tag="ACZPCR_09355"
     CDS             7637..9487
                     /locus_tag="ACZPCR_09355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008395094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1231119.1"
                     /translation="MAFFSRVSFRRRDRELAAAAGIVLAAAALLLTLVGNMISDNQKT
                     MIQMQSGQLRSISESVAKQIEVFADEMASDLEMETKLNQFIEAERSLEQGQQEPMAQL
                     LEEFLEGREGSVEGMAWESGGQRIECWAEGQEPLTLQTASFMTEENADLAVSILQDEN
                     GWCYLKLAKMTQAGNRLSCLLSFNDIYEKTAAHIKMGKNGYVMVKSSDGLILMHQVEE
                     QIGQKVLSGRMEMYPDLDFTDLTRLIEHQNQGRGGVEVYHSYWWIEDPPRPVKKVSAY
                     EPAWIGDDFLIVSAVIDYADITLPMQKSIVKIVAAAVLLVIFFGLFLLLTGRMFLHQK
                     KVEKENVRLKEVNERLEELRKREEAMAHQQRLQLIGTMTGGIAHEFNNLLTPIMGYSA
                     MMLSEMEPQNPYYGDIEEILNSAEKAKEIIGQISAFSGKNAKKSFQELLISQTAAKAM
                     LVAESGKPEQVKLSMQLVFEPYWMWGNETQIHQIVLNLCTNAFHAMGKSGGCLTVSGV
                     VRQGKDIAENRFFSDKPEQEFYELTFSDTGCGMSEEVKSQIFDPFYTTRKAGEGTGLG
                     LYLVHRMVEEHKGTITVESEPGRGTVFRIYFPVFRKDEKGDFNGTYCDSK"
     gene            9462..10105
                     /locus_tag="ACZPCR_09360"
                     /pseudo
     CDS             9462..10105
                     /locus_tag="ACZPCR_09360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006776805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            10205..10798
                     /locus_tag="ACZPCR_09365"
     CDS             10205..10798
                     /locus_tag="ACZPCR_09365"
                     /EC_number="2.7.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0050145 - nucleoside monophosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidylate kinase-like family protein"
                     /protein_id="HIR1231120.1"
                     /translation="MNQVITISREYGSGGRELGVRLAKALGIPFYDKEVISMAADDME
                     IAEEAFRRYDEQIEIPDYLNRERSRVLSSLYEVPISDQLFVAQSNVIRRLASRGPCVV
                     VGRCADRILENSVNLFVHAGMEQRAERIMAAEGRSDRKETERHIREIDEKRRDYYQYY
                     TGSSWGRAQNYHLCLDTGLAGVDGCLKAALAYLEAVQ"
     gene            complement(10961..12196)
                     /locus_tag="ACZPCR_09370"
     CDS             complement(10961..12196)
                     /locus_tag="ACZPCR_09370"
                     /inference="COORDINATES: protein motif:HMM:NF012955.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HIR1231121.1"
                     /translation="MRPFKKKQPFLKNISLRLALAVLLTAVLTLAGCSGGGKTSPQET
                     SKQPSSSQSQSQENEAPAGAGSADTQLHFIDVGQGLSVLAESDGHFLLFDGGDRKTSS
                     LVVSYLKEQGVETLDYVIASHYDADHLNGVVGALNAFQVSQVLAPDYETDTKVFQSFQ
                     SAIEKNRIPLSHPAPGDSFTLGNASFTVLAPQDKSYQNANDYSVAIRLTAGDVSFLIT
                     GDAEVESEAEMVKSGLPLESTVYVAGHHGSASSSSWDFLQKAVPEYVVISCGAGNSYG
                     HPHVETMEKLQSMEIPVFRTDKQGTVTVSTDGTSLTWSADPCNDYSSGDPDDKPARPA
                     GSGQPALPEENAPDQEAAESGSHTYILNTNSKLIHMPDCKSVTDMSEANKQTWSGESY
                     DKCLEEHPGYRGCKSCDPR"
     gene            complement(12219..12623)
                     /locus_tag="ACZPCR_09375"
     CDS             complement(12219..12623)
                     /locus_tag="ACZPCR_09375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002603907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HIR1231122.1"
                     /translation="MNPNSSEAQTEKNGKRSKKHDLFLVLAVLAAAALLFTGRKLFFS
                     KSPAAVTVSVDGTELMTLDLNQDGEQIIESPGGGTNRLVIKDGAVHMEEASCPDKVCI
                     KQGTISKTGQSIVCLPNRVIVTITGTDSQKTD"
     gene            complement(12613..13683)
                     /locus_tag="ACZPCR_09380"
     CDS             complement(12613..13683)
                     /locus_tag="ACZPCR_09380"
                     /EC_number="2.7.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HIR1231123.1"
                     /translation="MNREQAKGALGLLAGLALLAGCFFLDKKEQAREPMVRSDFLLNT
                     FVTISVYDSDDETLLNGAMDLCREYENRFSKTIEGSEIYQLNHRSPEETVFFLSSDTA
                     SLIEEGLFYSRLSDGAYDLTVEPLSSLWDFTSGQNVIPPKEDIETAAAKVGYENLALE
                     GNTLTFLSPDTTLDLGSIAKGFIADRLKEYLVSQGVESAIINLGGNVLCIGSQPDGEP
                     FRIGIQKPFASHNETVGFVEIDDASVVSSGVYERCFTADGKNYHHLLDPRTGYPYDNG
                     LISVVIICPESVDGDALSTTCFSLGLEKGMELLDSTEDAAGIFITEDYELHFSEGAAE
                     LSIYDEDGKPLKNLNEVTDYES"
     gene            13783..14301
                     /locus_tag="ACZPCR_09385"
     CDS             13783..14301
                     /locus_tag="ACZPCR_09385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007710205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HIR1231124.1"
                     /translation="MSRREQKTGRAALCGMLIALAFLFSYVETLIPISLGIPGVKLGL
                     ANLVTIVGLYLVSLPQLILISLVRIVLAGLTFGNGFSMIYGLAGGALSLLFMLLARKT
                     GWFSQAGVSVAGGVGHNVGQLVIAAFVVENRAVFYYLPFLLAAGSAAGAVIGMLGGIV
                     TKRIGPAVRRLS"
     gene            14403..15914
                     /gene="galT"
                     /locus_tag="ACZPCR_09390"
     CDS             14403..15914
                     /gene="galT"
                     /locus_tag="ACZPCR_09390"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009295946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HIR1231125.1"
                     /translation="MIYEAVHKLVTYGLRTGLIAECDKIYATNQILEVMGLDEYEEPE
                     REPEHIDLESVLKELLDYAHETGVLAEDSVVYRDLFDTKLMNCLMPRPSEIISKFWNI
                     YHEKSPKDATDYYYKLSQDSDYIRRYRIARDMKWTTDTKYGVLDITVNLSKPEKDPKA
                     IAAAKLMKQSGYPKCQLCMENEGYAGRANHPARNNHRIIPITVNDSAWGFQYSPYVYY
                     NEHCIVFNGKHTPMKIDRAAFVKLFDFVKQFPHYFLGSNADLPIVGGSILTHDHFQGG
                     NYTFAMAKAPIEKYFTIPGFEDVEAGIVKWPMSVLRTRAKDPDRLIELGDQVLGCWRG
                     YTDEAAFIFAETDGEPHNTITPIARKNGDMFELDLVLRNNITTEEFPMGVYHPHQELH
                     HIKKENIGLIEVMGLAVLPSRLKGELAKLGEYMVSGKDIRSDAEIEKHADWVEEFLPK
                     YPSVTAENVDEILKQEVGLVFEKVLEDAGVYKCTKEGREAFAQFLHTVGFKER"
     gene            15923..16720
                     /locus_tag="ACZPCR_09395"
     CDS             15923..16720
                     /locus_tag="ACZPCR_09395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HIR1231126.1"
                     /translation="MLIKEEFLKKYNIAENEFRSANISFKELEKIYSHYCLLEPELRS
                     ISRDFLDQYLYDTERAGIHSYRYRLKDPGHLIEKIIRKRNESLESYREINSSNYYKYL
                     TDLIGIRVFFLYREDWRGFHEYITSQFENNPEIYVEDRLRDFDEDPNHWYIAERPKSY
                     RRIGDSKIYDKNLIDIKSDGIYRSIHYIVKYKGYYVELQARTLFEEGWSEVDHDIVYP
                     YFQDDVMLKDFSTLLNRLSGMADEMSSYFRRLKEAKEKYQMEEDHTL"
     gene            complement(16839..17864)
                     /locus_tag="ACZPCR_09400"
     CDS             complement(16839..17864)
                     /locus_tag="ACZPCR_09400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006855555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HIR1231127.1"
                     /translation="MNHETLTGFLRRKQINISVQTYLIDALGAMAFGLFASLLIGTIF
                     GTLGEKTGIEIFNTIAVYAKGATGAALGVSISYALKSPQLVIFSAATVGIAGNELGGP
                     VGALAATIIASELGKLVSKETRVDILVTPGVTIISGVLTAQLVGPGVSAFMTGFGDLV
                     KTATVMQPLFMGILVSALIGIALTLPISSAAICIMLSLDGLAGGAATAGCCAQMIGFA
                     VLSYRENGFGGLLAQGLGTSMLQMPNIVKNPKIWLAPTLASMVTGPVSTMVFKLENIA
                     AGSGMGTCGLVGPIGVYTAMPEGGASMWMGILMVCFLLPAVLTLLFGWFFRRIGWIRE
                     GDLKLDL"
BASE COUNT         4603 a         3916 c         5030 g         4372 t
ORIGIN      
        1 atgggaaagt tgttatagtc tctgcggtta tacactttta gctgcgctgc aaagtcctca
       61 aaggaataga acaggtgggt tgcatagaaa cgctcattat ccttcctgtg gcttcgttcc
      121 accttcccgt tgtggcgtgg ggtaaaggga cggatgagtt tgtggcggat cccatggagt
      181 tccagatgtt tctggaacag ggtaggcttt tccttgtgag aggtaaaacg gttagtaaat
      241 tctgtaccat tatcagtctg aatgcattcg atcggacagg gaaaggcttt taccaaatgt
      301 tctacaaact gggcggaaga ataggtgctg tgctcttcaa atgcctccac aaaccgccag
      361 cgggagtact cgtcaattgc cgtgtactgg aaaaactgtt ttccaatgac ctggggattt
      421 ttcaggcagg cagagggaac gaatttcaca tcaacctgga tccgctgtcc gggataatcc
      481 atagcttcgt agggcttagg gatgtacttt ggattgggtg gatgcacagc catgattcct
      541 tgtttcctga ggaaacgata gagtccggaa atagaacggg aatagccgcg ctgccggagt
      601 tttacccaga aaacaaccag accagcatga ggatttctgc ggcgcatatg ccggatcagc
      661 ttgatttcat caaccgtatg ctgatttggg tgggaatgtg gcctgcggga gagttcgcgc
      721 agagagtccc aggagccgtc atagcgtcgc ttccagcggt aaatatactg tctgtttgtt
      781 ttatatttca tggcagcttt ggtaacgcca aatttttcag catattgaat tagagataga
      841 cgatacctca tatcttgtgt tatagtagcc atagcagaga actcctttat gtgatttttg
      901 ttgtggtgac taaaatataa cacaaaggca gcgtctctgc tttttaaata ttcagttgta
      961 acacatgtat tgtaatccta catttgaata gtcttaagat aggaaattct gatgacagag
     1021 gggagaaatt ctgatatgat taaaaaatac gtattttgct gaagacggtt ttgacagacg
     1081 caggagacga tttgaaagaa caggatgtga aataaaatga aacagagagt atcagctggc
     1141 agaaatattg atctgacaga gggaccggta gcgcgctcca tgtggacctt cgctctgccg
     1201 ctcattgccg gaaatctgct ccagcagttt tataatgtgg cggataccct gattgtgggc
     1261 cgttttctgg ggccgggcgc tctggcggcg gtgggatcct cctacacggt gatgacattt
     1321 cttacctctg tgattctggg actctgcatg ggaagcggag tgctgttttc catgctctgc
     1381 ggggcgggag atacagagcg gatgaagaac agctttgtcc agtcgtttct tttcattggg
     1441 ctggtaacgg ctctggtgga ggcgctttct ctgatatttc tggatcccat gatgggaatt
     1501 cttaagattc cgtcagatat tttagaagag acgggagaat atctgcaggt tatttttatg
     1561 ggccttatgt ttacctttgt gtacaattat tttgccgcgc ttttaagggc tctgggaaat
     1621 tctgtggttc cccttttatt tctggcagtt tcagctctgg gaaacattgt cctggatctg
     1681 gtatttattc tgaaatttca tatgggaaca gccggagcgg cctgggctac gattctggcc
     1741 cagtttctgt ctgctctggg aattggcctc tatgtatgtg taaaaatgcc tcatctgctg
     1801 ccgggaaggc gtcactttta cagggacagg aatattttaa agacgatttc caggtattcg
     1861 attttaacct gcgcccagca gtcggtcatg aattttggaa ttctcatggt gcaggggctt
     1921 gtaaacagct acggagtcac ggttatggcg gcttttgcgg cagcagtgaa gattgattcc
     1981 ttcgcctata tgccggtgca ggattttgga aacgcatttt ctaccttcat tgcccagaat
     2041 cagggagctg gaaaaacgga gcggatccgc ctgggactta gagcggccgt gctgagctcc
     2101 ggcctgttct gcctcgttat ctcggcggtg attgtgtgtt ttgcagggcc gctcatgact
     2161 atttttatca gtcctgagga gacagaaatt atcagaattg gcgtccagta ccttcacata
     2221 gagggggcct gctatgtggg aatcggctgc ctgtttctgc tctacggact ctaccgcggc
     2281 ctgggacggg caggagtgtc cgtggttctc acaattattt ccctgggaac gagagtggct
     2341 ctggcctatc tcttgtcgcc tgttccggcc atcgggcttc tgggaatctg gtgggctgtg
     2401 cctatcgggt ggttcctggc cgatgctgcg ggattctggt atttctggag aatggggagg
     2461 agaaaaggag tttagagagg cgtcagtgcg caggggacgg agtgttttgc agcagaaaga
     2521 agtattttat ttgaatatat gattgaaatt aattgaaaaa tcaatcgtaa atttttacga
     2581 ttgatttttt gcgtatttct gcatataata ggctcaataa aagtggaaag agggtgcgat
     2641 tgatatgcgt gaagcaaggg tattggaatt caaggaaaca attacgaata cttttttaaa
     2701 gacagtcagt gccttttcga attatggcgg aggaacaatc ctttttggag ttgatgacga
     2761 tggaacagtg aaaggtctgc cagatgtaaa gcaggcttgc ctggatattg aaaataaaat
     2821 caatgacagc atctcacctc agccgaacta tacgcttgaa atacagaatc atgatcagac
     2881 gataaaactc actgtaaaaa gcggccttca gaaaccttat ttatataaat caaaagcata
     2941 taaacgaaac gatacggcga cgatagaggt agataccttg gaattttcaa ggcttatatt
     3001 agatgggaaa aatatcagat ttgaagaact gccatgtaaa gaccaggaac tgtccttcaa
     3061 agttttacgc cgtaagctga aggaaagcat tcagattgaa acatttaatc aggatacatt
     3121 gaaaacattg aacctctatg acaatgtaaa tggctttagc aatgcagcgg ggctgttggc
     3181 agacaaaaat cattttcctg gaattgatct tgtgaaattt ggtgaaaata tcagcgtcat
     3241 tcaaaggaga gcaacatttg agaatatctc tgtgttagac gaatatgaaa agacaactgc
     3301 tgtgtttaga gattattacc aatacgaggt aatacagggg gccgatagga aaagggtgga
     3361 gaaaatacca gaagccgctt ttagggaagc agttgccaat gctctgattc atagggcatg
     3421 ggatgtggat tctcaaatca gagtttcaat gtttgacgat agaattgaaa tcgtatctcc
     3481 tggcggtctg ccatctggaa taacagcaga agaatatttg tcaggcagac tttctgtttt
     3541 aagaaacaga aatcttgcaa acgtgtttta cagattggga tttgtggaga tattcggaac
     3601 aggaattaca aggataaaac agctgtacga agaaagttta ataaaaccgg agtttgaagt
     3661 atcggaaaat gcaatcaaaa ttatgcttcc agtatttgaa agcaatgtta atttgacaga
     3721 agacgaaaaa gtaatttata cactcctaag caagactatg ctgaagccca taagcgaaat
     3781 tgcgccatat gcgccttttg gtaaatcaaa gactacaaag ttactgaaag atatggaaga
     3841 aaaaggcgtg attacagttg aaggaaaagg tagagggacg aagtatatca ttaactggaa
     3901 ataagtaaac tgaactgtat aatttatgag tttatgctgt tttgccagca tccaaagaga
     3961 gagcgaggag gagattatct attttaacgc agtgggaatg ggaatcgagg atctggcggt
     4021 ggtgaccaga gcctaccggg ccgcgaagga gcgggggctg ggagtgaccg tcaactactg
     4081 ggctgagcag aaaacgcaaa gagaagctct tgtcccacac acctttttat gtcataatag
     4141 acgtattgca gaaaacatat gacagaaagg aaacagggat tgatgatgaa acaggaagct
     4201 tctctggagc aatggaactc tctttaccag gctgccgccg ctgtgacgaa gctggccccc
     4261 tgggaagatt tttggaatac agatttaatt gtcattcagg agagcaggaa acaggaaccg
     4321 ctgtttatga gcatatctgg ccggggaatt cacaatcgcg gcgtgacgat gtatatagga
     4381 aacgacggac tggaggattt tgacctgaca gagagcacca gaggggaggc tctggcctcc
     4441 tttgctctca gagaacagcg ctgtctgtcc tttaagctct gcgatcggga ggatgtgcct
     4501 caggagcagc gggatatgat aaaggagctg ggcctggcct tcaggggacg gggaaaatgg
     4561 ccctgctttc tctcctggcg gaaggcctac gcgccctgga cgctggatgg agaggaagtg
     4621 cagattctga cagaggcgtt ctgccgtatg gaagaagcag tgaaggacgc cagagacggc
     4681 gcggttaagg tgcgttttga acggggagaa tttctctgga gaagccggga tgaagagact
     4741 ggagactggc ggacggtatc cgctcccatt ccttccggca gaaggaaata ccccctggcc
     4801 cgtcttcgaa gcgtggatca gatcgaggcg gtgaaatccc gtcccagaag cataaacgag
     4861 ctgtccatgg atttgtttta tatgaacgcg gaggtagtgg aagagggcta tgacaggccc
     4921 ttcttcccca gagcgttcct tgtaatggaa aagagaacca gggcggttct caatatgcag
     4981 gtgctggagc cggaggacaa cgaggtcagc gccattcttc atttcctgtt aaattacatc
     5041 atgaagagcg gaagaccgag gactgtctat gcgagaaatc cctggatttt tgcggcgctg
     5101 acagatacct gtgagaagtg cgggattcct cttctttcca gcgctctgga ggagatggag
     5161 gaaatggtga atcagctgac agacgcaggc atggaggaat agaaaaaggg cgttccggtt
     5221 tggttttggg cggaacgtcc tgccgctcct gtcaggaagg atcctggcag gagaaggtat
     5281 atccgattcc ccacaccgtt ttaatgtagc agggattttt cgcctgatcc tcaattttat
     5341 ttctcagatg gctgatgtaa accatgatca cgttgtcgtc cacagcagag tgattccaga
     5401 ccagctcata gagctgctcc ttcgtgaata cctggccggg atgggacagg aacagccgca
     5461 tcagcacatg ctctctggag gagagaggaa tcggagttcc atttttaaaa agctccatgg
     5521 taattgtatt ataggagaag ggaccggcag tgatgatgcc ggtcttttcc tgttttccgg
     5581 tctgattgcg gcggatcagg gctttgatct ttccgcccag aatgacggga ttaaaaggct
     5641 ttgaaacgta gtcgtcagct ccgatgtcca ggccgtaaag agtgtcgaag tcatcggttc
     5701 ttccgcttaa aaccatgatg ggagtggtat ttccagactc ccggagccgt ttgatagcgt
     5761 gaaagccgtc atcgtttcca ttcatcataa tatctaataa aatcagtgca aaggattccc
     5821 gggaagccag atggacggct tccgttccgt cgcaggcagt gacagcctga aagccgctgc
     5881 cttccaccac ccggattaac aggcggcgga cagcgggatc atcgtctgca atgagtatct
     5941 tttcttcggc cataaaaggt ctcctctctg tttcattctc tttgttttga acatctgcgt
     6001 tatattcatg ctaccacaaa tgatggaaaa aagcaaaaaa cagctgtcga aaatgtgcta
     6061 agatcttgta aaaaaaggaa aatcttaaag ttttttaaga ctttttcagg agatgttaag
     6121 gacagggctc tatactggga atcagaaata agttctgccg gaggagggaa aggccggcag
     6181 aggagagaga gggaaaagta tgtatttagc acttctgggc tttgccatga tcgtagtctt
     6241 catgggactg attatggcga aaaaactgag cccctttacg tcactgattc tgattccgat
     6301 tgtgttcgga cttctggcag gatacggctg ggatacctta gagtatgcca tgacgggaat
     6361 taaggatgtg gccagtacct ttgccatgat gactttcgcc attctgtatt tcggcgtaat
     6421 gctgacggcg ggaatgttcg acccgatggt ggacaaggtt gtttcctggt gtaagggaga
     6481 cccgttaaaa gttttagtgg gaacagccgt attagctgcc tttgtttctc tggacggaga
     6541 cggaaccact accgttatga tctgctgtac agccatgatt ccgatttatg agcggttaaa
     6601 gattaagaaa atctatctgg caaccctgat tatccttcag aactgtatta tgaacctgat
     6661 tccgtggggc ggccccacag ccagagtcat gtctgtcatg aatctggacg caggagagat
     6721 tttaggaccg ttggtgcctg gaatggcttt atctgctgtt tatgtaatcg gcgtttccta
     6781 ctacctggga ttaaaggaga gaaagcgcct gggcatcagc agggatgtgg agaaccacgc
     6841 ggtaaaggtg gagctgtctg aggatgagaa ggcatggaag agaccgaaac tgattctgtt
     6901 taacctggct ctgacagccg gcattattgt ggctctgatc atgggacttg cctcctccgc
     6961 cattcttttc ggcgtgggaa cagccgttgc tctgttagtg aactacccga accagaaggt
     7021 tcagagaaat gttatcagct ctattgcacc agacatgatc aacgtagtta tgatggttct
     7081 gggagccggc gtattaatgg gaatcttaaa cggaccggag gacgcgggta tgtcaaacgc
     7141 catcgcagaa ttcctggtag ccgtgattcc ggaatctctg gcaaaatact ttgccattgt
     7201 catcgctgtg atcagtgcgc ctggcaccta tctgttaaat aacgacgcgt tctactacgg
     7261 agtgcttccg ccgttagcgg ccaccgccca ggcatacgga ttcacagact taaatattgg
     7321 atttgccgcc ctgatgggac aggcattcca cttcttgagt ccgcttgtac cgtttatcta
     7381 cctgttaatg gacaagacag agatcacgct ggcacagtac cagggctaca ttttcaaatg
     7441 gtgtatcgga attttcgtta tttttatggc catgggcctt gtgacaggat atctgcctat
     7501 cctctaggaa actggggctg gactgctgta aaggaaaagc ctcaaacatg aaaaatgaat
     7561 aaaaaacagt ttcagccgga gatttgacag gaaaatctcc ggctgttaca atttatgcag
     7621 aagggggaga ggaaagatgg cttttttcag ccgcgtttct tttaggagaa gagacaggga
     7681 gctggcggcg gcagcgggaa tcgtactggc ggcagctgcc cttttgctga cgctggtggg
     7741 aaatatgatt tccgacaacc agaaaaccat gattcagatg cagagcggac agctccgctc
     7801 catttcggag agcgtcgcca agcagatcga ggtatttgca gacgagatgg cttcggatct
     7861 ggagatggag acaaagctta accagtttat tgaggcggaa cgctccctgg aacagggaca
     7921 gcaggaaccc atggcgcagc tgctggagga atttctggag ggaagggaag gcagcgtgga
     7981 gggcatggca tgggaaagcg gcggccagag gatagaatgc tgggcagaag ggcaggaacc
     8041 tctgactctt cagacagcca gctttatgac agaggagaac gcggatctgg cagtctctat
     8101 tctgcaggat gaaaacggct ggtgctatct gaagcttgct aagatgactc aggcgggaaa
     8161 ccgcctttcc tgccttttga gttttaacga tatctacgag aagacggctg cccacataaa
     8221 aatgggaaaa aacgggtatg tgatggtgaa atcctcagac ggactgattc tcatgcacca
     8281 ggtggaggag cagattggcc agaaggttct gtcaggcaga atggaaatgt atccggatct
     8341 ggattttaca gatttaacac gattaattga gcatcagaac cagggcaggg gaggcgtgga
     8401 agtctaccat tcctactggt ggattgagga tcctcctaga ccggtaaaaa aggtttccgc
     8461 ctatgaaccg gcctggattg gagacgactt tctcattgtc agcgctgtca tcgactatgc
     8521 ggacattacc ctgcccatgc agaagtccat cgtgaagatt gtagccgcag cggtgcttct
     8581 tgtgatcttt ttcggcctgt ttctgctttt gactggaagg atgtttcttc accagaaaaa
     8641 ggtggagaaa gaaaacgtcc ggctgaagga ggtcaacgag cggctggaag agctgagaaa
     8701 gagggaggaa gccatggccc accagcagcg gcttcagctg attggaacca tgacaggagg
     8761 aattgcccat gagttcaaca acctgctgac tccgattatg ggatactctg ccatgatgct
     8821 gtcggaaatg gagccgcaga atccttacta tggggatatt gaggaaatct taaattctgc
     8881 tgagaaagcc aaggagatta tcggacagat ttcagctttc agcgggaaaa acgccaagaa
     8941 gagctttcag gagcttttaa tcagccagac ggcggccaag gccatgctgg tggcagaatc
     9001 gggaaagccg gagcaggtaa agctttccat gcagctggta tttgagccct actggatgtg
     9061 gggaaatgag actcagatcc accagattgt attaaattta tgcaccaacg cctttcatgc
     9121 catggggaag tccggcggct gcctgaccgt cagcggggtg gtgagacagg gaaaggatat
     9181 agcggaaaac cgtttcttct ccgacaagcc ggagcaggaa ttttatgagc tgaccttttc
     9241 tgacactggc tgcggcatga gcgaggaagt gaaaagccag attttcgatc ccttctatac
     9301 caccagaaaa gcgggggagg gaactggact ggggctttac ctggttcaca ggatggtgga
     9361 agaacacaaa ggaaccatca ctgtggagag cgaaccgggg cggggaacgg tgtttcggat
     9421 ttatttccct gtgttcagaa aagatgaaaa aggagatttt aatggaacgt attgtgattc
     9481 gaaatgagag accggatgac tatcagatcg tggaggagat cacgagagaa gctttttata
     9541 atatctatgt gctggatgtg tggagcacta tctggttcat gtgatgcgaa gccacgagga
     9601 ttttatacca gaacttgatt ttgtaatgga actggacgga gaggtgatgg gaagtattat
     9661 gtatacaaag gcttccctga cagatgaaga ctgcgtgaaa aaggagattc tgacctttgg
     9721 cccggtatgc attctgtcga aataccagag aaggggatac gggaaaatgc tgatagagca
     9781 ttccttccag acggctctga agctgggcta tgacgcggtc gttatattcg gaagtcctgc
     9841 caactatgtg ggctgtggtt ttaaaagctg caggaagttc catgtgagcg tagagggcgg
     9901 tctgtatccg gcagccatga tggtcaggga actgattccc ggagcgctgg gagagaaaaa
     9961 ctggacgtat cgtgacagcc ctgccatgag catcagtgag gaggaagcca gagcgtatga
    10021 cgatacgctt gcgccgaagg agcgtaaata tcagcccagc caggaggaat tttatattat
    10081 gagccattcc tttctgcaga attaggaaga gcctgtgaaa gcggaaaaat ccagtgtaca
    10141 aatttcccgt caaacgctat aataaaagta attttaccag cggattcaga gagggggata
    10201 cagaatgaat caagtcatta caataagccg tgaatatgga agcggaggcc gggagctggg
    10261 cgtgaggctg gcgaaggctc tgggaattcc attttatgac aaggaggtta tctccatggc
    10321 tgccgacgat atggagattg cggaggaggc gttccgaaga tatgacgagc agatcgagat
    10381 tcccgattat ttaaacaggg agagatcgag ggttctttcc agcctgtatg aggtgccgat
    10441 ttccgatcag ctgttcgtgg cgcagtctaa tgtaatacgc cgtctggcct cccggggccc
    10501 ctgcgtggta gtcggccgct gcgcggaccg gattctggag aacagcgtca atctttttgt
    10561 ccatgccggg atggaacaga gagcagagcg tatcatggct gccgagggcc gctctgacag
    10621 aaaggaaaca gagcgccata tccgcgagat tgatgagaag agaagggatt attaccaata
    10681 ttatacaggc agttcctggg gaagggctca aaactaccac ctgtgcctgg atacagggct
    10741 ggcgggggtg gacggctgtc tgaaggcggc gttagcctac ctggaggcag tgcagtaggg
    10801 cagcagaagg cgtcctttcg cctgtgcgct gcctgctcag aagaaatttg tctgtacaaa
    10861 tttatctgta aggaataaag aataaagcgt tttataaaaa cagccagggc ctgtctgaga
    10921 ctctggctgc ttgaatattg gatgaaagat gttatcggat ttaccgcgga tcacagcttt
    10981 tgcatccccg gtagcctgga tgctcctcca ggcatttgtc gtaggattct ccggaccatg
    11041 tctgtttgtt cgcttcactc atatctgtta cgcttttgca gtccggcata tgaatcagct
    11101 tagaatttgt atttaaaata taggtgtggg aaccgctttc ggcagcttcc tgatccggag
    11161 cgttttcctc tggaagagca ggctgaccgg aacctgcagg tctggccggc ttgtcgtccg
    11221 gatcgccgga ggagtagtcg ttacaggggt ctgcagacca ggtgagagac gttccgtctg
    11281 tggaaacagt gaccgttccc tgcttgtctg tgcggaaaac gggaatttcc atagactgaa
    11341 gcttttccat ggtctccacg tggggatgcc cgtaagaatt gccggctccg cagctgatta
    11401 ccacgtattc cggaaccgcc ttctgaagga aatcccagct gctggagctg gcgcttccat
    11461 ggtggcccgc cacgtagacg gtactttcca gaggaagccc ggacttcacc atctcggctt
    11521 cgctttccac ctccgcgtcc cctgtaatca gaaagctcac atccccggct gtcaggcgga
    11581 tagcgaccga gtagtcgttg gcgttctgat agcttttatc ctggggagcc agaaccgtga
    11641 aggaggcgtt tccgagcgta aaggaatcgc cgggggccgg gtgggagagg ggaatacgat
    11701 tcttctctat ggcagactgg aaagactgga acacctttgt gtctgtctca tagtccggcg
    11761 ccagcacctg ggatacctgg aaggcgttca gggcgcccac tacgccgttt aagtgatctg
    11821 catcgtaatg ggaggcaatc acatagtcca gagtctccac tccctgctct tttaaatagg
    11881 agacaaccag ggaagaagtt ttcctgtctc cgccgtcaaa cagaagaaaa tggccgtctg
    11941 attctgccag aacagagagg ccctggccta cgtcgataaa gtgtaactgg gtgtcggcag
    12001 aaccagcgcc tgcaggagct tcgttttcct gactctgact ctgggaggaa gaaggctgct
    12061 tagaggtttc ctgtggggaa gtttttccgc ctcctgagca gccggcaagg gtgaggacgg
    12121 ctgtcaggag cacagccagg gccagccgga gagaaatatt ctttaaaaag ggttgttttt
    12181 tcttaaatgg tctcataatc aggtctcctt tttatgtgct aatcagtttt ttgtgaatca
    12241 gttccagtga tagttacaat cacccggttt gggaggcaga caatggactg ccctgtcttg
    12301 gaaatcgttc cctgctttat gcagaccttg tccgggcagg acgcttcctc catgtgaacc
    12361 gctccgtctt tgatcaccag gcgatttgtg ccgccgccgg ggctttctat gatttgttcc
    12421 ccgtcctgat tcaaatcaag agtcataagc tctgtcccgt ccacgctgac tgtgacagcg
    12481 gccggggact tggaaaaaaa cagctttctt cctgtaaaga gaagagctgc ggctgccagg
    12541 acagccagaa ccaggaacaa atcgtgtttt ttagagcgtt tcccgttttt ttctgtctgt
    12601 gcttcagatg agttaggatt catagtcagt cacctcattc aggtttttca ggggctttcc
    12661 gtcttcatca tagatggaga gttcggccgc gccttcggaa aaatgcagct catagtcctc
    12721 tgtaatgaag atacctgctg cgtcctcagt ggagtctaaa agctccatgc ccttttccag
    12781 ccccagggaa aagcaggttg tgctcagggc gtccccgtcc acagattccg ggcagatgat
    12841 gacaacggaa atcaggccgt tgtcataggg atatcctgtc ctggggtcca gaaggtggtg
    12901 gtaatttttt ccatctgcgg tgaaacagcg ctcgtagacg ccggaggaca ctacagaggc
    12961 gtcgtcgatt tccacaaagc cgacggtttc attgtggctg gcaaagggct tctgaatgcc
    13021 gatccggaac ggctccccgt ctggctggga gccgatgcag agcacgtttc cccccagatt
    13081 gatgatggcg ctttccactc cctggctgac caggtattcc ttcaggcggt ctgcgataaa
    13141 gcccttggcg atggatccca gatccagggt ggtgtccggc gagaggaagg taagcgtatt
    13201 tccctcaagc gccagatttt catagcccac ctttgccgct gccgtctcaa tatcctcctt
    13261 cggcggaatg acgttctgtc cgcttgtgaa gtcccagaga gagcttaaag gctctactgt
    13321 cagatcgtag gccccgtccg acaggcggct gtaaaagagc ccctcctcga tcagagaggc
    13381 tgtgtcgctg ctcaggaaaa agacggtctc ttctggagac ctgtggttca gctggtaaat
    13441 ctcgcttccc tcaatggtct tgctgaatct gttttcatac tcgcggcaca gatccatggc
    13501 tccgtttaag agagtctcgt cgtcggaatc atagacggat atggtgacaa aggtatttaa
    13561 caggaagtca gagcggacca tgggctctct ggcctgttct tttttgtcca gaaaaaaaca
    13621 gccggctaaa agcgccagcc cggccagaag ccccagggct cctttcgctt gttctctgtt
    13681 cattttatta tttcctcttg tactttgcgc ttcggaagat ataatagaaa gaagcgcaga
    13741 acgatagttt tctgtctaac atactagcaa aggaggcaga acgtgtcaag aagagaacag
    13801 aaaacaggaa gggcggctct gtgcggaatg ctgattgccc tggccttcct gttcagctat
    13861 gtggagacct taattcccat cagtctcggc atcccgggag tgaagctggg actggccaat
    13921 ctggtgacaa ttgtgggcct ctatctggtc agtctgcccc agctgatttt gatatccttg
    13981 gtccgcattg tcctggcggg actgaccttt ggcaatggat tttccatgat ctacggtctg
    14041 gcaggcggcg ctttgagcct tcttttcatg ctgctggcca gaaaaacggg atggttcagc
    14101 caggcgggag tcagcgtggc cggaggcgtg gggcacaacg tgggacagct cgtcatcgcc
    14161 gcctttgtgg tggaaaatag agcggtcttt tattaccttc ccttccttct ggcagcggga
    14221 agcgcggccg gagccgttat aggaatgctg ggcgggattg tgacaaagcg gatcggcccg
    14281 gcggtgagaa gactttcata gaggcagagc gccgggacgc taaaaacagg gttggcaaac
    14341 aatggcagat gaagtaaaat ggaagacgga tacgaaatat tacaacaaaa ggagatgcgg
    14401 gtatgattta tgaagcagta cacaaactgg taacatacgg ccttcgcaca ggtctgattg
    14461 cagagtgcga taaaatttac gccacaaacc agattttaga ggtgatggga ctggacgagt
    14521 acgaggagcc ggagagagag ccggagcaca ttgatctgga atctgtgtta aaggagcttc
    14581 tggactatgc ccacgagact ggcgtactgg ctgaggacag cgttgtctac agagatctgt
    14641 ttgacacaaa gctcatgaac tgcctgatgc cccgcccaag tgagattatc tctaagttct
    14701 ggaatattta ccacgagaaa tctcccaagg atgcgacgga ctactactac aagctgagcc
    14761 aggattccga ctatatccgc agataccgca ttgcccggga tatgaagtgg accactgata
    14821 ccaagtacgg ggtgctggat attacagtca acctgtccaa gccggagaag gatcccaagg
    14881 ccatcgctgc ggcgaagctg atgaagcaga gcggatatcc caagtgccag ctgtgcatgg
    14941 agaacgaggg atatgcggga cgggccaacc atccggccag aaataatcac agaattattc
    15001 ccattacagt caacgacagc gcctggggct tccagtattc tccctatgta tactataacg
    15061 agcactgcat cgtgttcaac ggaaagcaca cgccgatgaa gattgaccgg gcggcctttg
    15121 tgaagctgtt tgattttgta aagcagtttc cgcactattt cctgggttcc aacgcagatc
    15181 ttcctattgt aggaggttca atcctcaccc acgatcattt ccagggcgga aactatacct
    15241 tcgccatggc gaaggcgccg attgagaaat attttacaat tcccggcttt gaggacgtgg
    15301 aggcaggcat tgtaaagtgg cccatgtctg tgctgagaac gagagccaag gatccggacc
    15361 gcctgattga gctgggcgat caggtgctgg gctgctggag aggctacacg gacgaggcgg
    15421 cctttatttt cgctgagaca gacggagaac cgcacaacac catcacgccg attgccagaa
    15481 agaacgggga catgttcgag ctggatctgg tgctcagaaa caacattacc acagaggagt
    15541 tccctatggg cgtttaccat cctcatcagg agcttcacca cattaagaag gaaaatatcg
    15601 gcctgatcga ggtgatgggc ctggccgtgc ttccgtcccg tctgaaggga gagctggcga
    15661 agttaggaga gtacatggta tccggaaagg atatccgctc tgacgcagag attgaaaagc
    15721 acgcggactg ggtggaggaa ttccttccta agtatccgtc cgttacggct gaaaacgtag
    15781 atgaaatcct caagcaggag gtgggcctgg tgttcgagaa ggtattggag gacgccggcg
    15841 tttataaatg tacgaaggag ggcagagagg cctttgcaca gttccttcat acagtcggat
    15901 ttaaggagag ataggagaca gaatgctcat taaagaagaa tttctgaaga agtacaacat
    15961 tgcggagaat gaattccgct ctgccaatat cagtttcaag gaactggaga aaatctacag
    16021 ccattactgc ttgctggagc cagagcttcg ctccatcagc cgtgattttc tcgaccagta
    16081 cctgtacgat acggagcggg cggggattca ttcttaccgc taccggttaa aggatccggg
    16141 ccatctcatt gagaagatta tcagaaagag aaatgagagc ctggagagct atcgggagat
    16201 taacagctcc aactattata agtacctgac agatctcata ggaatccggg tgtttttcct
    16261 gtaccgggag gactggagag gtttccacga gtacattacc agccagttcg agaacaatcc
    16321 tgagatttat gtggaggaca ggctgagaga tttcgacgag gatccgaacc actggtacat
    16381 tgcggagcgg ccgaaaagct accggagaat cggagattct aagatctatg acaaaaatct
    16441 gattgacatt aagtcagacg gaatttaccg ttccatccac tacattgtga agtacaaggg
    16501 atattatgtg gagctgcagg ccagaactct ctttgaggag ggctggagcg aggtggatca
    16561 cgatattgtg tatccgtact tccaggacga tgtaatgtta aaagactttt ccaccctgtt
    16621 aaaccgcctg tccggcatgg cagacgagat gagctcctac ttcaggcgtc tgaaggaagc
    16681 gaaggaaaag tatcagatgg aagaggatca tacgctgtaa catgagataa agaaaaaaga
    16741 ggaagcgcaa tgtctgccgt tccagtgaaa gatgctggaa cacattgcct tcctcttttt
    16801 atgctgcaga aaccgcacgc cggcggtaca ggccggatct acagatccag cttcaggtcg
    16861 ccctccctga tccagccgat ccggcggaag aaccagccga agagaagagt cagaacggcg
    16921 ggaagcagga agcagaccat aagaatgccc atccacatgg acgcgccgcc ctccggcatg
    16981 gcagtgtaga cgccgatggg gcctaccagg ccgcaggtgc ccattccgga tccggcggca
    17041 atattctcca gcttaaacac catagtggag acaggtcccg tcaccatgga agccagagtg
    17101 ggagccagcc agattttcgg atttttgaca atgttcggca tctggagcat ggaagtgcca
    17161 agtccctggg ccaagaggcc tccgaaaccg ttttcgcggt agctgagtac ggcgaaaccg
    17221 atcatctggg cgcagcagcc ggcagtggcg gctcctcctg ccagtccatc caggctcagc
    17281 ataatgcaga tcgccgcgct gctgatggga agagtcaggg caatgccgat gagggcagat
    17341 accaggattc ccatgaagag gggctgcatg acagtggcag tttttaccag atcgccgaag
    17401 ccagtcatga aggcggagac gccggggcct acgagctggg cggtgaggac gccggagata
    17461 atggtgacgc ccggagtgac gagaatatcc accctggtct ccttggaaac cagctttcca
    17521 agctcagagg cgataattgt ggctgccagg gctcccacag ggcctcccag ctcgtttccc
    17581 gcaatgccga ctgtggccgc agagaaaatg acaagctgcg gagattttaa cgcgtaggaa
    17641 atcgacacgc ccagggccgc tcctgtggcg cctttggcgt agacggcgat ggtattaaag
    17701 atttcaatgc ctgttttctc tcccagagtt ccgaaaatcg tgccgatgag aagggaagcg
    17761 aagaggccga aggccatagc gcccagggcg tcgatcagat aggtctggac ggagatattg
    17821 atctgctttc gtctcagaaa tccggtcaga gtttcgtggt tcatttgtgt ttgttcctcc
    17881 cgtttgaata aaaatacatg gccgttgtcc agctggaacg g
//
LOCUS       DBMDUW010000051        17534 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1889_length_17534_cov_3.604887, whole genome shotgun sequence.
ACCESSION   DBMDUW010000051 DBMDUW010000000
VERSION     DBMDUW010000051.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 17534)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 17534)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17534
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1889_length_17534_cov_3.604887"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(304..2001)
                     /locus_tag="ACZPCR_09405"
     CDS             complement(304..2001)
                     /locus_tag="ACZPCR_09405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006779547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004819 - glutamine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006425 - glutaminyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HIR1231128.1"
                     /translation="MEENTKTVTEAEEKESVSKNFIEREIEKDLAEGVYNHVQTRFPP
                     EPNGYLHIGHAKSIILNSGLAEEYHGKFNLRFDDTNPTKEKTEFVQSIIEDVKWLGAE
                     FEDRLFFASDYFEKMYECAVLLIKKGKAFVCDLSAEQIREYRGDFNTPGKESPYRNRS
                     IEENLELFENMKNGMYKDGEKVLRAKIDMASPNINMRDPVIYRVAHMTHHNTGDKWCI
                     YPMYDFAHPIEDAIEHITHSICTLEFEDHRPLYDWVVRECEFENPPRQIEFAKMYLTN
                     VITGKRYIKKLVEDKIVDGWDDPRLVSIAALRRRGFTPESIRKFVELAGVSKADSSID
                     YAMLEYCVREDLKLKKARVMAVLDPVKLVIDNYPEDQMEELTAPCNLENPELGDRVIP
                     FGKELYIEREDFMEEPPKKYFRLFPGNEVRLMNAYFVTCTGCEKDADGNVTVVHCTYD
                     PETKGGNAPDGRKVKGTIHWVAKETAVQAECRLYENLVDEEKGKLNADGTLNLNPNSL
                     TILKECYVEPSLKDAKAYDSFQFVRNGYFCVDCRDSAPEYPVFNRIVSLKSSFKITK"
     gene            2261..3214
                     /locus_tag="ACZPCR_09410"
     CDS             2261..3214
                     /locus_tag="ACZPCR_09410"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006779540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HIR1231129.1"
                     /translation="MRHDNRKIALIGTGMVGMSYAYSLLNQNVCDELVLIDVNKKRAL
                     GEAMDLNHGLAFSSSNMKIYAGGYDDCTDADIVVICAGVAQKPGETRLDLLKRNTEVF
                     QSIIEPVTASGFNGIFLVATNPVDIMTKITCTLSGFNPRRVLGTGTTLDTARLRYLVG
                     DYLKVDPRNVHAYVIGEHGDSEFVPWSQAMVATKSIRELVKESHGSICEQDLEKISEE
                     VRTAAYKIIEAKNATYYGIGMALTRITKAVLGNENSVMTVSAMLRGEYGQNGVFVGVP
                     CIINQNGIQRVLPLSLEEGELEKLNSSCEVLKESYHALGMD"
     gene            complement(3378..3671)
                     /locus_tag="ACZPCR_09415"
     CDS             complement(3378..3671)
                     /locus_tag="ACZPCR_09415"
                     /inference="COORDINATES: protein motif:HMM:NF027968.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase C-terminal domain-containing
                     protein"
                     /protein_id="HIR1231130.1"
                     /translation="MFYTYQRLIQYRKQYDIFTEGSYRLLEPSHPQLFLYERILGKER
                     LLAAGNFSGQWCRLALPEGYEAGTILESNYGRSSLEQTMELKPYESLMIYLAE"
     gene            complement(3669..5062)
                     /locus_tag="ACZPCR_09420"
                     /pseudo
     CDS             complement(3669..5062)
                     /locus_tag="ACZPCR_09420"
                     /inference="COORDINATES: protein motif:HMM:NF012356.7"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
     gene            complement(5124..5873)
                     /locus_tag="ACZPCR_09425"
     CDS             complement(5124..5873)
                     /locus_tag="ACZPCR_09425"
                     /inference="COORDINATES: protein motif:HMM:NF016668.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HIR1231131.1"
                     /translation="MKKLLIRADDIGYSEAVTAGILSALESGLVKSAGLMVNMPFTEK
                     SVELIKDRTDICFGLHVNLVIGPACCQDREAVKDLVDGQGRFIASRIRREEFARGLDS
                     MSYAQVCREIEAQAERYEALMGRRPEYMDLHGVENDTLIQAVRDMAERCGVPATPYSG
                     QTVLLEEMLHHDFYESGEAFEAFFSKPCCRIQEGVNNLLIMHPGFVDYDLIQSSSLTM
                     DRVYEHALLCDPKVKECLKRQQVELLSFRDL"
     gene            complement(5873..7321)
                     /locus_tag="ACZPCR_09430"
     CDS             complement(5873..7321)
                     /locus_tag="ACZPCR_09430"
                     /inference="COORDINATES: protein motif:HMM:NF014437.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HIR1231132.1"
                     /translation="MKRYLNKLMQELSLLGKAMLVPITVMPVAGIIGLIFGADFLNIP
                     VIAGLSSIVFGNVDFLFVLGAAGAYSKAKDKTTVMVGAVVAFLVFKQTLGTLNPDVNA
                     GVFGGILVGIAVAYTYNHTHKLKAPAVLSFFANEKCVVSLSPIIGLIFAWLFSVIWIY
                     PQNAMDAFGVWLGGMGAVGVFLFIFLNRALIPLGLHQVLNAYILFEMGSYTNAAGEVV
                     HGEIPRFMAGDPTAGWFWTGFYVIMMFGIPAIALAIYKMAREDRKKEVKGVMTAGAVT
                     AFASTVTEPIEFSFLFASPKLYLLHSFYSGLGGAVLALLGSRLGTFNGAGILDYVLCF
                     RYGDRAWMVIPMGIVFFFLYYITFKKIIIKDQVETPGRERELELSETAGEEEKQLKLF
                     HSNYAYMAKKLLQNCGGPENIVSVANCLTRLRLEVKDAGLLNDENIKKTGAKGVIRLN
                     NNSVQIVIGTEVKNVREEFEMQLEELRKQAED"
     gene            7511..8233
                     /locus_tag="ACZPCR_09435"
     CDS             7511..8233
                     /locus_tag="ACZPCR_09435"
                     /inference="COORDINATES: protein motif:HMM:NF019322.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTRA domain-containing protein"
                     /protein_id="HIR1231133.1"
                     /translation="MAKEKYSAIYGALKKTILNHGYDRTKMLPSEAHLIEEFQCSRNT
                     VRRAIQQLNQEGLVQSINGKGVVVLEQIPDEDKYTFSFNNIMGMREIQKNRGAALSTR
                     VLLFETVPVTEELSRKSGFSIGKEAYRIHRLRLVDGEPVFLDCNYFLCDAVPGLTAEI
                     AQNSVYEYIEQTLGLKILGSRRRLRIEAAASEDIDYLHLDGANCVGALYINGYIDDGS
                     IFEYTKIKYAPNYLSFEEFVKR"
     gene            complement(8295..10277)
                     /locus_tag="ACZPCR_09440"
     CDS             complement(8295..10277)
                     /locus_tag="ACZPCR_09440"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-translocating pyrophosphatase"
                     /protein_id="HIR1231134.1"
                     /translation="MNELVWLAPIAAVAALVFALILASGVKKQSPGNDRMKEISGAIK
                     EGAQAFLKAEYKILVLFVLVLFVVIGLGIGNWITAVCFLVGAAFSTMAGYFGMQVATD
                     ANVRTANGAKEGGMGKALGIAYKGGAVMGMCVVGLGLLGISVIYLFTKDVNVLTGYSL
                     GASSIALFARVGGGIYTKAADVGADLVGKVEVGIPEDDPRNPAVIADNVGDNVGDVAG
                     MGADLFESYVGSLVSAVTLGVVAYQVEGAFFPLILAGIGIIASMIGTFFVKGKEGTDP
                     QKSLNLGSYVAYAIVIGASLVLSNLFFGRMHEAAAIISGLAVGFIIGQATEIYTSDKY
                     NSVKKIAEQSETGSATNIISGLAVGMKSTVVPILFIAIGIIIAYSTAGLYGIALAAVG
                     MLATTGSTIAVDAYGPIADNAGGIAEMSGLDESVRNITDKLDSVGNTTAAIGKGFAIG
                     SAALTALALFVSYAQAVNLTTIDILNPKVIIGLFIGGMLPFLFSAITMESVSKAAYKM
                     IEEVRRQFRQDPGILKGESRPDYTSCVGISTTAALHEMLVPGVISVVVPIAMGLLLGT
                     DALGGLLAGSLVTGVLMAIFMANAGGAWDNAKKYIESGTHGGKGSDSHKAAVVGDTVG
                     DPFKDTSGPSINILIKLMTIVSLVFAPLFLSIGTIF"
     gene            10720..12066
                     /locus_tag="ACZPCR_09445"
     CDS             10720..12066
                     /locus_tag="ACZPCR_09445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HIR1231135.1"
                     /translation="MDNLPGLLLIQAGLIFLNAFFAAAEIAVISLNHAKLKKLQESGD
                     RTAGRLLAMAEEPSGFLSTIQIGITLAGFLGSAFAAENFSDPLTHWIYDILGIQVLSP
                     AALNTVSVIFITLILSYFTLIFGELVPKRAAMQKPYEIARFSCRIVAAIAFLAKPVIA
                     FLAFSTNLVLRLLGMKTEAEEENLTEEELRMMIELGKEKGAIDEDETEWIQNVFDFRD
                     TSILSSMTREADIVSLDEHSTDQEIISIIRESGLSRLPVYTKDREDIKGILYTREYLL
                     NLTAPHPRSLDQLLHDAYFVPESIHADDLFRDMQTKKVHMAIVVDEYGNLSGLITLED
                     LLEEIVGNIYDEFDPVMEPEIEKVDENLWRFPGDTPVEEAAEQMGVTLPDKEEYNTIG
                     GMVLSCLRTFPKDGTTVDAELHGLSLHVEKIANRRIESVLVKKLPDAEKTVKESEA"
     gene            complement(12204..13811)
                     /locus_tag="ACZPCR_09450"
     CDS             complement(12204..13811)
                     /locus_tag="ACZPCR_09450"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002601647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HIR1231136.1"
                     /translation="MKKKLPLAALAMAGILGASVWFQPLAAYAAVWEKSGSGYEMPDG
                     TSIRGVLRRGIDVSHWQQNVDWNQVAADDVDFVMLGTRYKGEVDPNFRTNADAAHAAG
                     VELGAYIYSYATSVEMAEQEADFILDLVKDYPISYPIAFDAEDAGTLGTLPPDQISAI
                     INAFCRKIEAAGYYPMVYANEYWLNNKIDKSTLDYDVWVARYNVMYTYDSPAIWQATN
                     TGSVNGIAGNVDIDFQFKDYASVIPANTWREIAGKRYYYQNYAMQKNSWINDGNGWYY
                     MNESGNPSTGWKNLEDGVYYLAQDGRMQTGWQELDGSWYYFKDSGRMALNWQQVDGIW
                     YYLGTDGKRRAGWQDIDGGRYYLGTDGRMASGWQKIDESWYYLGTDGKMTTGWQDIDG
                     KRYYLGADGRMETGWKQMDGHTYYLNSDGSMAVGWKQSGDTWYYMNGEGHMQTGWIQA
                     DGALYYLNDSGAMAANTVLERDGVKYQAAANGVCTEIPAENAAEGQAGEQSQAGTEGS
                     QNTGGQSAETQSSQNTGSGPAGPASDI"
     gene            complement(13950..14573)
                     /locus_tag="ACZPCR_09455"
     CDS             complement(13950..14573)
                     /locus_tag="ACZPCR_09455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004071486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4317 family protein"
                     /protein_id="HIR1231137.1"
                     /translation="MIQREDMLELTRRMTPARSCISRIAGAYFDEEGYVDGTFNTNFL
                     RLSLSERTKQLALAKTVPFSDTNVQLKDYKISREARRPGSIWQLLDGILQSEMKNDGL
                     LDLFYEVLGETYQPGAPYAFFLFYGRYDVPAKAEDKARLEDSEELYEYLIGTISPLAG
                     EYEPGKAEFGFLYPAFRDRRSEKEYVNLFERIPERTHRELTQWLLKG"
     gene            complement(14660..14833)
                     /locus_tag="ACZPCR_09460"
     CDS             complement(14660..14833)
                     /locus_tag="ACZPCR_09460"
                     /inference="COORDINATES: protein motif:HMM:NF020376.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HIR1231138.1"
                     /translation="MTFITTAYGIKLGYVPREDNKIAARLMDAGKILFGRILMKEKKG
                     SWIKIYVKVFLRE"
     gene            complement(14775..15845)
                     /locus_tag="ACZPCR_09465"
     CDS             complement(14775..15845)
                     /locus_tag="ACZPCR_09465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HIR1231139.1"
                     /translation="MKNLEQYRGCLIGGAAGDALGYAVEFPGTDAAVKKYGKSGSKNC
                     KLHNGIAPVSSVTQMTLFTANGLLLGTTRGMTRGIMGSYPAYIAACYKDWLQTQSAAY
                     PLRPRSPYSWLVNEPELFARRDPGNTCISAIINGADGTIDAPMNQSKGCGGMVRVAPI
                     GLYLGGRRYESDKIDMIGAETAALTHGHELGYIPAAAFVHIIQRLSHNEDISLYEAVR
                     DTEQALLRLFDGKKYLDEQIRLIDRAIELSNGTFDDLEAVQELGQGWTAEETLAIAIY
                     CSLKYSDDFEQALIAAVNHSGASSSTGAVTGSIMGTYLGYSSIPDKYIENLELKNVIL
                     ELADDLYHDCIWNKAWLCAKGG"
     gene            complement(16227..16505)
                     /locus_tag="ACZPCR_09470"
     CDS             complement(16227..16505)
                     /locus_tag="ACZPCR_09470"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231140.1"
                     /translation="MAQHKVSVFLTGRAAAQLAGDDLAGAVGVMDFMSDYIMTVFGSL
                     DIIPAVDGKDGGLAALGAGLTPGRRRSGGRSGSFFHDRNICFSRRIPE"
     gene            16524..16910
                     /locus_tag="ACZPCR_09475"
     CDS             16524..16910
                     /locus_tag="ACZPCR_09475"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231141.1"
                     /translation="MLGADIDFIVRGIDSKTRSVAVSCREAMRRSSLEDLGIKADIKS
                     ISENTDRDNLQKCRIQGKYAGRVTDVHKGIVYVRLSNGVNAAAHSCYDYRMPGKKDDV
                     SFAVTRLDMERGVAVGIIPRIIRQNL"
     gene            17081..>17534
                     /locus_tag="ACZPCR_09480"
     CDS             17081..>17534
                     /locus_tag="ACZPCR_09480"
                     /inference="COORDINATES: protein motif:HMM:NF024700.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HIR1231142.1"
                     /translation="MDGSKRYLKSAVIYGANASGKSNVLHAFWFMVNYVLTSHNQQLH
                     KAIERSPFKFDCETPSRPSCFEAIFTANGIRYAYGFSVTDKAVIEEYLYYYPNGRQAI
                     IFERQNTNNFRFTVDVDEQSMLKNRTSPNKLYLSVASSWSYSKVIPVLE"
BASE COUNT         4270 a         4749 c         3837 g         4678 t
ORIGIN      
        1 ttatggaatg cattccattt tggaagcata aaaaattggg gaaatactac ccctactaac
       61 tcatatgcaa acagaactct catgacaagt tctatttaac taaattataa cagcggcact
      121 ctgaaatgtc aacggatggt ttcataaaaa ttgcacaaaa acccatattt ctctcttctt
      181 tttccttgac aaagaaaaca cacctattct tttattttgc cgggttaaac tggtaaactg
      241 tataaaaggc cggataggag aggtttcttc ttcctcccct gtccggcctt ctctgctttt
      301 attctatttt gtaatcttga aggagctctt cagagatacg atacggttga ataccggata
      361 ctccggcgcg ctgtctctgc agtctacgca gaaatagccg tttctcacaa actggaaact
      421 gtcataggct ttggcgtcct tcagggacgg ctctacatag cactccttta agatagtcag
      481 ggagttggga ttcagattca gggttccgtc tgcattcagc ttgcccttct cctcgtctac
      541 cagattctca tagaggcggc actctgcctg aactgctgtc tctttcgcta cccagtgaat
      601 ggttcccttc acctttctgc cgtctggggc gtttcccccc ttggtctcag gatcgtacgt
      661 acagtgaacc actgtcacat tgccgtccgc atccttctcg cagccggtac aggtaacaaa
      721 gtaggcgttc atcaggcgga cctcattgcc tgggaaaagg cggaagtatt tcttcggagg
      781 ctcctccata aagtcttccc gctcaatgta aagctctttt ccaaacggaa tcactctgtc
      841 gcccagctcc ggattctcca gattacacgg agccgtcagt tcctccatct ggtcttccgg
      901 ataattgtca atcaccagct tcaccggatc caggacagcc atcactctgg ccttctttaa
      961 cttcagatcc tctctcacgc agtactccag catggcgtag tcgatggaac tgtcagcctt
     1021 ggaaacgcct gccagctcta cgaacttccg gatggactcc ggcgtaaagc ctctccttct
     1081 gagagctgcg atggagacaa ggcgcggatc atcccatccg tctacgattt tatcctccac
     1141 cagtttctta atgtatctct ttcctgtgat cacattggtc aggtacatct tggcaaactc
     1201 aatctggcgc ggcggattct caaactcgca ctctcttacc acccagtcgt acagcgggcg
     1261 gtgatcctca aactccagcg tacagatgga atgtgtgata tgctcgatgg cgtcctcaat
     1321 cggatgagca aaatcgtaca tcggataaat gcaccacttg tcgcctgtgt tgtggtgagt
     1381 catatgagcc acgcggtaaa taaccggatc tctcatgttg atattcggtg acgccatgtc
     1441 gatcttggcg cggagcacct tctctccgtc cttgtacatg ccgttcttca tattctcgaa
     1501 cagctccagg ttctcctcga tgcttctgtt ccggtacggg ctctcctttc caggagtatt
     1561 gaaatcgccg cggtactcgc ggatctgctc tgcgcttaaa tcgcacacaa acgccttgcc
     1621 ctttttaata agaagaaccg cacactcata catcttctca aagtaatcgg aagcgaaaaa
     1681 gagtctgtcc tcaaactctg ctcccagcca cttcacatcc tcaataatgg actggacaaa
     1741 ttctgtcttc tccttcgtcg ggttcgtgtc atcgaagcgc agattaaatt tgccatggta
     1801 ttcctctgcc agtccggaat tcaggataat ggacttggcg tgtccaatgt gaaggtatcc
     1861 gttcggttcc ggtggaaatc tggtctggac atggttataa acaccttcag ccaaatcttt
     1921 ctcaatctct ctctcgataa agtttttgga aacggattct ttctcttccg cttctgtcac
     1981 tgtctttgtg ttttcttcca tctcatttcc tccgttattc tcttgttcat aaatatgatg
     2041 atattttatc atatcatatt tttcccggaa ggaaaaggta ctttctgggt ataaaactct
     2101 attttctgcg cataaatctc tattttccgg aaatcataga agaaacaatt ttcctctttt
     2161 caattttcaa taattgtgat attattaaca atatgcagtt agtcgcaact atccggctgt
     2221 ctgcaggctg atacaccaaa cacaggagga cttctttatg atgagacatg acaatcgaaa
     2281 aatcgccctg ataggaactg gaatggtagg aatgagctat gcctattctc tgttaaacca
     2341 aaacgtctgc gacgagctgg tattaattga tgtaaataaa aagagagctc tgggggaggc
     2401 catggatctg aaccacggtc tggccttttc cagttccaat atgaaaatct acgccggagg
     2461 ctacgacgac tgcacagacg ctgatattgt agtgatctgc gcgggggttg cccagaagcc
     2521 aggagaaacg cgcctggatc tgttaaagag aaacacagag gtgttccagt ctattatcga
     2581 gcctgtcacc gcctccggct ttaacggtat tttcctggta gccaccaatc cggtggatat
     2641 tatgacaaaa atcacctgca ccctctccgg ctttaaccca agacgcgttc tgggaacggg
     2701 tacaacgctt gatactgccc ggctccgcta cctggtaggc gattatctga aggtagatcc
     2761 aagaaacgtc cacgcctacg tcattggaga gcacggagac tctgagtttg ttccgtggag
     2821 ccaggccatg gtagccacca aatccatccg ggagctggta aaggaatccc atggttccat
     2881 ctgcgagcag gatctggaaa aaatttccga ggaggtccgg actgccgcct acaaaatcat
     2941 tgaggcgaaa aacgccacct actacggcat cgggatggcg ctcacacgaa ttacgaaggc
     3001 tgttctgggc aatgaaaaca gcgtgatgac tgtctccgcc atgctgcggg gagaatacgg
     3061 gcagaacggc gtttttgtgg gcgttccctg cattatcaac cagaacggca ttcagcgggt
     3121 gcttcccctc tccctggagg aaggagagct tgaaaagctg aacagctcct gcgaggttct
     3181 gaaggaatct taccacgctc tgggaatgga ttaatatcct attaaaaagg cggaagaacc
     3241 gtcccccagg gggacaggcc ttccgccttt ttctattgtt ccattctatt tatttcgtta
     3301 tctttctttt ctgcgctttt tccctgtttt ataataggaa gaaacagctc tccacagagg
     3361 tccaaaggca ctgtccccta ttccgcgaga taaatcatca ggctctcgta gggctttaac
     3421 tccatcgtct gctccaggct gcttctgccg taattggact ccagaatcgt tcccgcctca
     3481 tatccctccg gcagcgcaag acgacaccac tggccgctga aattgccggc tgccagaaga
     3541 cgctctttcc caaggattct ctcatacaga aacagctgcg gatgagacgg ctccagaaga
     3601 cggtagcttc cctccgtaaa aatatcatac tgctttctgt actggatgag tctctgatac
     3661 gtgtagaaca cggaagactt atttttaagc tcattttctg cgctgatgcg gtctggattt
     3721 gaagcaagcc acggctctcc ctggctgaag ccgtgatgct tcgtgttgtc ccactgcatg
     3781 ggagttctgg cgttatccct ggacttctgc cttaagatca gaagagcctc ctcatggccg
     3841 acgccgtctt ctctcatctg ccagtaggct cccgtgctct ccctgtcgtc gtactcctcc
     3901 agcgtctcaa agcacgcgtt tctcatcccc agctcttctc cctggtagat gtaagtggtg
     3961 ccctgcaggc caaacagggt aattgctaac agcttggcgc tctcctcccg gtaaaaggta
     4021 tcgtttccaa acctagataa ggctctgggc tgatcgtggt tggaataaaa cagcgcgttc
     4081 catccgcctc ccgcctccat cttattctgg aaataggact gtgtctcttt cagcttctcc
     4141 agggaaaaca tctgattggt ccacttgctt ccttataatc tgtcttcata tggtggaagc
     4201 tgaataccat ggacagctcc tccctgtcct ctctggtgta gagaacgcac tcctccggag
     4261 tggtggagga catctctcct actgtcacca ggccataagg cttaaatacc tcctgattca
     4321 ttaaatggag atattcgtgg atcctcggcc cgtccgcata gtgggttctg ccgtctccct
     4381 taggaccggt aatcggatcg tccggaagcc ccggagtctt ggacagcaga ttgaccacat
     4441 ccagacggaa gccgtccacg cccttttctg cccagaattt taatatttta atgcattctg
     4501 cccggaccgc ctcattttcc cagtttaaat ctgcctgtgt ctcctcaaac aggtggaggt
     4561 agtattggcc gctcttctcc tccttttttc aagccggacc tgaaaaacgt gagatccagt
     4621 tattgggcac agagccgtca ggcttcggat cgcggaagaa gtagtaatcc ctgtaagggc
     4681 tgtccggctc cgataccgcc tttttaaacc actcgtgctc tgtggaggtg tgatttaata
     4741 ccatatccat gataatgcgg attcctctcc tatgggcctc ttttaacagc agctcaaatt
     4801 cctccatagt tccataaacc ggatcaatct gatagtaatc ggcaatgtca tagctgttat
     4861 ctctctgcgg tgaaacgtac atcggcgtaa gccagatcaa atctgccccc aaacacttaa
     4921 tgtagtcaag tttttcaatg atgcccctga tatctccgat tccatcccca ttggaatcct
     4981 taaagcttct ggggtaaatc tgatataccg tggccttttt ccaccagttc ttctcctgtc
     5041 ctgtcttgga tactccctcc atcttccgcc ttcctttcct gttttgacat tcctctgtcc
     5101 gcttttcctt actctccccg cctttacaga tcccggaagc ttaaaagctc cacctgctgc
     5161 cgcttcagac actccttcac cttcggatcg cacagcagag cgtgctcata cacccgatcc
     5221 atagtcaggg aggaggactg gatcagatcg taatccacaa agcccggatg cataatcagc
     5281 aggttattga ctccctcctg aatgcggcag cagggttttg agaaaaacgc ttcgaacgct
     5341 tccccgctct cgtaaaagtc gtgatgcagc atttcttcca acagaaccgt ctggccgctg
     5401 tagggagtgg cgggaacgcc gcagcgctcc gccatatccc gcaccgcctg aataagcgta
     5461 tcgttctcca ccccatgaag gtccatatac tccggccgcc ttcccatcag cgcctcgtac
     5521 cgctctgcct gcgcctcgat ttcccggcac acctgagcgt aggacataga atccaggccc
     5581 ctggcaaact cttctcttct gatccggctg gctataaagc ggccctggcc gtcaaccagg
     5641 tctttcacag cctcccggtc ctggcagcag gccggtccga tgacaagatt cacatgaagg
     5701 ccaaagcaga tatctgtcct gtcctttatc agctccacgc tcttctcagt aaacggcatg
     5761 ttgaccatca gccctgcgct ctttacaagg cctgactcca gagcagacag gattccggca
     5821 gtaactgcct cgctgtatcc aatatcgtcc gcccgtatta acagtttttt cattagtcct
     5881 ccgcctgctt tctcagttcc tctaactgca tttcaaattc ttctcttaca ttcttaacct
     5941 ctgttccaat gacaatctgc acagagttat tgtttaagcg gatcacaccc ttggctcccg
     6001 tctttttaat attctcgtcg tttaaaagac ctgcgtcctt tacctcaagt ctgaggcgcg
     6061 tgagacagtt ggccacgctg acgatgttct ccgggccgcc gcagttctga agaagcttct
     6121 tagccatgta agcgtaattg ctgtggaaca gttttaactg cttctcctct tctccggctg
     6181 tctcagaaag ctccagctct ctttcccgtc ccggagtctc cacctggtcc ttaatgataa
     6241 tcttcttaaa ggtaatgtag tacaggaaga agaatacgat tcccatcgga atcaccatcc
     6301 acgccctgtc tccatagcgg aagcagagca cataatccag aattccagct ccgttaaagg
     6361 ttcccagtct ggaacctaaa agcgccagaa ccgctccgcc cagtccagaa tagaaggaat
     6421 ggagcagata cagcttcgga gacgcaaaca ggaaggaaaa ctctatgggc tctgtaaccg
     6481 tagaggcgaa ggctgtgaca gcgcctgccg tcatcacccc ctttacctcc tttttcctgt
     6541 cctctctggc catcttataa attgccaggg caatggccgg aatgccgaac atcataatca
     6601 cataaaatcc agtccagaac catccggcag tcgggtcccc tgccataaag cgcggaatct
     6661 ctccgtgaac cacctcgcct gccgcattgg tgtaggagcc catctcaaac agaatgtagg
     6721 cgtttaatac ctgatgaagt cccagaggaa tcagcgcccg gttcaggaaa atgaacagga
     6781 atacgccgac agctcccata ccgcctaacc atacgccgaa cgcgtccatg gcgttctggg
     6841 gataaatcca gatgacggaa aacagccatg caaatatcag accgataatc ggagacagag
     6901 aaacgacgca tttttcattg gcaaaaaagc ttaacacagc cggagctttc agcttatggg
     6961 tatggttata cgtataagct acggcaattc ccaccagaat tccgccgaac acacctgcgt
     7021 taacgtcagg attcaaagtt cccagcgtct gcttaaatac taaaaatgcc acgacggctc
     7081 ccaccatcac tgtcgtcttg tcctttgcct tggagtaagc gcctgccgcc cccagtacaa
     7141 agagaaaatc cacgtttcca aatacaatgg acgaaagtcc tgcaatcaca ggaatattca
     7201 ggaaatcagc gccgaaaata aggccgatga ttccagctac cggcatgacg gtgattggta
     7261 ccagcatagc cttgcccagc agggataatt cctgcatcag cttgtttaaa tacctcttca
     7321 tatgttacct cctggttcag ggatctgctg ttctttcatc ccctcagatg gctttactat
     7381 acacctgttt aaacagattt gagctgatgc acaggaaact gccccctgca gaaatttttt
     7441 tcctctcctc ccttgccttt cctgctgttt ttatataaaa tttaggtatt gaatctgaga
     7501 ggtgaaacgt atggcaaaag aaaagtattc cgccatttac ggagcattaa agaaaactat
     7561 tttaaatcac ggatacgatc ggacgaaaat gcttcccagc gaggcccatc tgatcgaaga
     7621 gttccagtgc agccgcaaca ctgtgcggcg ggcgatccag cagctgaacc aggaggggct
     7681 tgtccagagt atcaacggaa agggcgtggt ggttctggag cagattcctg acgaggacaa
     7741 atacaccttt tccttcaaca atattatggg aatgagggaa atacaaaaaa acagaggagc
     7801 cgctctgtct accagagtcc tcctctttga aacggttcct gtcacagaag agctgagcag
     7861 aaaaagcggt ttttccatcg gaaaagaagc ctatcgcatc caccggctca ggctcgtgga
     7921 cggagaacct gtctttttag actgcaacta ttttctctgt gacgcagttc ctggactgac
     7981 tgctgagatt gcccagaatt ctgtttacga atacatcgag cagacgctgg gattaaaaat
     8041 cctgggttcc aggagacgtc tgcgcatcga ggcagcggcc agcgaggaca tcgactatct
     8101 ccacttagac ggagccaact gcgtgggagc gctttacatt aacggataca tcgacgacgg
     8161 aagtattttt gagtatacaa agatcaaata tgcgcccaac tacctctcct ttgaggagtt
     8221 tgtcaagcgg taacaaatgc ggtcaaaaaa aatccccggt cacagacagt gtgatcgggg
     8281 attttcttaa cctcctagaa aatcgttcca atagaaagga acagaggtgc aaatacaagt
     8341 gatacgattg tcatcagctt gattaagatg ttgatggacg ggccggaagt atccttaaac
     8401 ggatcgccga ctgtatcgcc gactacggct gccttgtggg aatcgcttcc ctttccgccg
     8461 tgagttccgc tctcaatgta cttctttgcg ttgtcccatg cgccgcctgc gttcgccata
     8521 aagatagcca tcagaacgcc tgttaccagg gaacctgcca gcagaccgcc taaagcatct
     8581 gtgcctaaca gaagacccat ggcaatcgga acaactacag agatcacgcc tggcactaac
     8641 atctcgtgaa gagctgcagt agtggaaata cctacgcagg aggtgtaatc aggacggctc
     8701 tcgcccttta agataccagg atcctggcgg aactggcgtc ttacctcctc aatcatcttg
     8761 taagctgcct tggaaacaga ttccatggtg atggcagaga acaggaacgg aagcatgcct
     8821 ccgatgaaga gtccgatgat aaccttcgga tttaaaatat caatggttgt aagattaact
     8881 gcctgtgcgt aagatacgaa gagagccagg gctgtcaggg ctgcagagcc gatggcaaag
     8941 ccctttccga tagctgccgt tgtgtttcct acgctgtcta acttatcagt aatgtttctt
     9001 acgctctcat ccagaccgga catctctgcg ataccgcctg cgttgtccgc gatggggccg
     9061 taagcgtcta cggcgatggt gcttcctgtg gtagccagca taccgactgc cgccagagcg
     9121 attccgtaaa ggcctgctgt agagtaagcg ataatgattc cgatggcaat gaagagaatc
     9181 ggaacaacgg tagacttcat acccactgca agtccggaaa taatgttggt agcagagcct
     9241 gtctcagact gctctgcaat ctttttaaca gagttgtact tgtcagaagt atagatctct
     9301 gtagcctgtc caatgataaa gcctactgca agtccagaaa taatcgcagc cgcctcgtgc
     9361 atccgtccaa agaacagatt gctcagaact aaggatgcgc caattacgat ggcgtaagct
     9421 acatagcttc caaggtttaa ggatttctga ggatctgtgc cctcttttcc ctttacgaag
     9481 aaggttccaa tcatggaagc gatgattccg attcctgcca gaatcagagg gaagaaggct
     9541 ccctctacct gatatgccac aactcccaga gtaacggcag ataccagaga acctacatag
     9601 gactcaaaca ggtcagctcc cataccggct acgtcgccta cgttatcgcc tacgttatca
     9661 gcgataacag ccgggtttct cggatcatcc tctgggatac caacttctac cttacctacc
     9721 agatcagctc ctacgtctgc agcctttgtg tagattccgc ctcctacacg ggcaaacagt
     9781 gcgatagagg atgctcccag gctgtagcct gtcagcacat ttacatcctt tgtaaagagg
     9841 taaatcacgc tgataccgag aaggccaagg cctactacgc acattcccat aacagcgccg
     9901 cctttgtagg cgattcccag agccttgccc atgccgccct cttttgcgcc gttcgccgta
     9961 cgcacgttag cgtctgtggc tacctgcatg ccgaagtatc cggccatagt ggaaaatgca
    10021 gctcccacta agaaacatac cgctgtaatc cagtttccaa ttcccagtcc gatgacaaca
    10081 aacagaacca ggacaaacag tacaaggatt ttgtactcag cctttaagaa ggcctgagcg
    10141 ccttccttga tcgcgccgga gatctccttc atcctgtcgt ttcccggcga ctgctttttc
    10201 acgcctgacg ccagaatcag cgcgaaaaca agcgccgcta ctgccgctat cggcgccagc
    10261 cataccaatt cattcatcac ttttcctccc ttaagtaatt gcttcgcccc gcggaacctg
    10321 cggaatcttt gtctttccac ggagtctttt gttttgcaga gatattctgt aaaacaaaaa
    10381 aatgcaagtt cggtataaca acctgcattt atataataga ataagaatac tattgaaatg
    10441 gcatttcgtc aatataatga taagatttta acgtgttttg acgctgtttt tttacttttt
    10501 tctgaaattt tatgcttttt ctttccctgc ttctttttat cagcctccct gcctgtccgg
    10561 ctccttatct gctaaggctt tgttaagctt agggctttct gattgcaatt attaaagctt
    10621 tttagtagaa tacctgtgtc gtccggccgg agccggcgct ttaaagttct gttttattct
    10681 tcaaaaaacc agttattaaa cgaaaaagga gtattatttg tggacaattt acctggacta
    10741 ttgctgatac aggcaggtct catctttctc aacgcatttt ttgcagcagc tgaaatcgca
    10801 gtcatttctc tcaatcacgc caaactgaaa aagcttcagg aatcaggcga ccggacggct
    10861 ggacgtcttt tagccatggc agaagagcca tccggctttc tctctaccat acagattgga
    10921 attaccctgg ccggttttct gggcagcgcc tttgcagccg agaatttttc ggatcccctg
    10981 acgcactgga tttatgacat tctggggatt caggttctct ctccggcggc cctgaatact
    11041 gtgtccgtca ttttcattac cctgatcctc tcctacttta ccctgatttt cggggagctg
    11101 gtccctaaac gggcagccat gcagaaaccc tatgagatcg ccagattttc ctgccggatc
    11161 gtagctgcca tcgcctttct ggcaaaacct gtgatcgcct ttctggcttt ttccacgaac
    11221 ctggtgctgc gtctgctagg aatgaagaca gaagcggagg aggaaaacct tacagaagaa
    11281 gagcttcgca tgatgattga gctgggaaag gaaaaaggcg ctatcgacga ggacgagacg
    11341 gagtggattc aaaacgtttt cgatttcagg gatacctcta tcctgtcctc catgacgaga
    11401 gaagccgata tcgtcagtct ggacgaacat tccactgatc aggagattat cagtattatc
    11461 cgggaatccg gcctgtcccg tctccccgtc tacacaaagg atcgggagga tatcaagggc
    11521 attctctata caagagaata tcttctgaat ctcactgcgc ctcaccccag gtctcttgac
    11581 cagctgcttc acgacgctta ctttgtgccg gaatccatcc atgcagacga tctcttccgg
    11641 gatatgcaga cgaagaaggt tcacatggcc attgtggtcg acgagtatgg aaatctgtcc
    11701 ggactgatta ctttagagga tcttctggag gagattgtgg gaaatattta cgatgaattt
    11761 gacccggtga tggaaccgga aattgaaaaa gtagatgaaa atctctggag atttcctggc
    11821 gacacgcctg tggaagaggc cgcggagcag atgggcgtta cgcttcccga taaagaggag
    11881 tacaatacca ttggaggcat ggttttaagc tgtcttcgga cgtttccaaa agacggaacc
    11941 actgtcgatg cagagctgca tggtctttcc ctccacgtgg aaaaaattgc aaaccgcaga
    12001 attgaatccg ttctggtgaa aaagctgccg gatgcagaga aaacagtgaa agaaagcgag
    12061 gcctaaagcc tggctttaga caaaaggaag catttcaaca gaataagtga ttgaaatgct
    12121 tccttttttg tatcaatttt aaattttaat aaaattgaga gaacgttctg cttttatgcc
    12181 atatcttcca gcaggcagct ctgctatata tcagacgccg ggcctgccgg gccgcttccg
    12241 gtattctgag aactctgtgt ctcagcgctc tggcctcctg tgttctggct tccctctgtt
    12301 cctgcctggc tctgctctcc tgcctggcct tccgctgcat tctcggccgg aatctctgtg
    12361 cagacgccgt ttgccgccgc ctgatatttt accccatccc gctcaagaac tgtgttcgcc
    12421 gccatagctc ccgaatcatt caggtaataa agggctccgt ctgcctgaat ccatccagtc
    12481 tgcatgtggc cttctccgtt catataatac caggtgtctc ctgactgttt ccagccgaca
    12541 gccatgcttc cgtcgctgtt taagtagtag gtatggccgt ccatctgctt ccagcccgtc
    12601 tccatccttc cgtcagcgcc cagatagtag cgttttccgt caatatcctg ccagcctgtg
    12661 gtcatctttc cgtctgttcc caggtaatac caggactcgt caatcttctg ccagccagac
    12721 gccattctgc cgtccgtacc cagatagtag cggcctccgt caatgtcctg ccagcctgcg
    12781 cgcctctttc cgtctgttcc caggtaatac cagattccat ccacctgctg ccagtttaaa
    12841 gccatgcggc cggaatcctt aaagtagtac caggatccgt ctaactcctg ccagccggtc
    12901 tgcatccttc cgtcctgggc cagatagtaa acgccgtcct ccaggttctt ccagccagtg
    12961 gaaggattgc ctgactcatt catataatac cagccgtttc cgtcgttgat ccagctgttt
    13021 ttctgcatgg cgtaattctg ataataatag cgctttccgg ctatctctct ccatgtattg
    13081 gccggaatca cggaagcgta gtccttaaac tggaaatcaa tgtccacatt tcctgcgatt
    13141 ccattgacag agccggtatt ggtcgcctgc cagatagccg ggctgtcgta tgtatacata
    13201 acattatacc gggctaccca gacatcgtag tccagcgtgg atttatcaat tttattgttg
    13261 agccagtatt cgttggcata gaccataggg tagtagcctg cggcctcaat cttacggcag
    13321 aaggcgttaa taatcgcgct aatctgatcc ggcgggagag ttcccagagt gccggcatcc
    13381 tccgcgtcaa aggcaatcgg ataggaaatc ggataatcct ttaccagatc cagaataaaa
    13441 tccgcttcct gctccgccat ctccacgctg gtagcgtagg aataaatata cgcgcccagc
    13501 tccacaccgg ccgcgtgggc tgcgtcggca ttggtcctga agttgggatc cacctcgccc
    13561 ttatacctgg ttcccagcat aacaaaatcc acatcgtctg ccgccacctg attccagtct
    13621 acgttctgct gccagtggga cacgtcgatt cctcttctca gtactcctct gatggacgtt
    13681 ccatccggca tctcatatcc gcttcctgac ttttcccata cagccgcata ggctgcaaga
    13741 ggctggaacc agacggaagc gcctaaaatt ccagccattg ccagagcggc cagaggtaat
    13801 ttcttcttca tatgttgatt ctccttttat caaatcgcct gatatatccc ttatagtcta
    13861 ccagatcctg ccgtttttcc tcaagaggca aatcttacga tttccatacg attttgcatt
    13921 tttatgcccc tttatcggga agaatcggct taccccttca gaagccattg cgtcagctct
    13981 ctgtgggttc tctccggaat cctttcaaac agatttacat actctttttc tgatcttctg
    14041 tcccggaatg ccggatagag aaatccaaac tccgcctttc ccggctcgta ttcccccgcc
    14101 aggggactta tcgtacctat cagatactca tacagctcct ctgagtcttc cagtctggcc
    14161 ttgtcctccg cttttgccgg cacgtcatat cttccgtaga ataaaaagaa cgcgtacggc
    14221 gcgcccggct gatacgtttc ccccagcacc tcataaaaca aatccaggag tccgtcgttt
    14281 ttcatttccg actgaagaat tccgtccaaa agctgccaga tactgcccgg acgcctggcc
    14341 tctctggaaa ttttgtaatc cttcagctgc acgttcgtat cagaaaacgg caccgtcttg
    14401 gccagagcca gctgctttgt ccgctctgag agcgaaagcc tcagaaagtt cgtattaaag
    14461 gttccgtcca catatccctc ttcatcaaaa taagctccgg ctatccggct gatgcaggaa
    14521 cgggcaggcg tcatccttct ggtcagctcc agcatatctt ctctttgaat cattgtttct
    14581 cctttcacct tttttatttt ttcttacaac ggtcgtccag aactgacgca cttgtgtgga
    14641 aactctctgc atcggcggat tattcgcgca gaaatacttt tacataaatc ttaatccagg
    14701 aacccttctt ttctttcatc agaattctgc cgaaaagaat ttttccagcg tccatcagac
    14761 gtgcggcaat tttgttatcc tcccttggca catagccaag ctttattcca tatgcagtcg
    14821 tgataaaggt catctgcaag ctccaatatc acatttttca gttccagatt ctcgatatac
    14881 ttgtcaggaa tgctactgta tccaagataa gtccccataa tactgcccgt taccgcacct
    14941 gttgaactgc tggctccgct atggttaact gccgcaatta acgcttgttc aaaatcgtca
    15001 gaatatttta gagaacagta aattgcaatt gcaagagtct cttctgcagt ccatccctgc
    15061 cccagctcct gtacagcttc caaatcgtca aatgttccgt tggataattc aattgctctg
    15121 tcaatcagcc ttatttgttc atctaaatat ttttttccgt caaacagccg cagcagagcc
    15181 tgttctgtgt cccttaccgc ttcatataag gaaatatcct cattatgcga aagccgctga
    15241 atgatatgta cgaaagctgc cgccggaata tacccaagtt catgtccatg cgttaaggcg
    15301 gcagtctccg ctcctatcat atctatttta tcactttcat accgtctgcc tcccaaatac
    15361 aggccaatgg gagcgacccg caccatcccg ccacagcctt tactctgatt cataggagca
    15421 tctatggttc catccgctcc atttataatt gctgatatac aggtatttcc cggatcgcgg
    15481 cgggcaaaca gctctggttc atttacaagc catgaataag gagagcgcgg cctcagcgga
    15541 taggctgcag attgtgtctg aagccagtcc ttatagcatg cagcgatgta ggccggatat
    15601 gatcccataa ttccgcgggt catgcctctt gtcgttccaa gcagcagacc attggcagta
    15661 aaaagcgtca tttgagtgac actggaaaca ggagcgatac cattgtgcag tttacagttt
    15721 ttgctgccac ttttcccata ttttttaacg gcagcatctg tgccaggaaa ctcaacggca
    15781 tatcctagtg catcgccggc agcgccgcca atcaggcatc ctctatactg ttctaaattc
    15841 ttcactccat cagctcctct tatatctgcc tacagcaaat taacgtccct tagagattcg
    15901 ttctgagtca ttcatgctgc gaatcttctg cgcaatattt tgtaatcttt aaacattata
    15961 ccttcaatca actcttttgc atagtcaaag cgcttaatag aattctttgt tgtaaactgc
    16021 atattcagga taacggtcag aataacgaat ttgtaccgcc tgctcctacc gtttcctcca
    16081 ggtctttatt ttttgaccag aagcacaaaa ggacatcttc ctaaaatttc ttttagaaaa
    16141 atgtccctct ttgtataaaa tatttacctg gactaatatg gatttttcac aaaaccgctt
    16201 gttaaaaccc attaagccac tttaaattat tcggggatac gcctgctgaa gcagatgttc
    16261 ctgtcgtgga agaaactgcc gctcctgccc ccactccttc ttctccccgg cgtcagcccc
    16321 gcccccagcg cagcaaggcc cccgtcctta ccatccacgg ccgggatgat gtcgagactg
    16381 ccgaagaccg tcatgatata atctgacatg aaatccataa cgcctaccgc acccgcaaga
    16441 tcatcaccgg caagctgggc cgcagccctt ccggtcagga atacgctgac cttatgctgc
    16501 gccaaaataa gatccttggc aacatgctcg gtgctgacat tgacttcatc gtgcgtggta
    16561 tcgactccaa gacccgcagc gtagctgtca gctgtaggga ggccatgcgg cgcagcagtc
    16621 tggaggactt gggcatcaaa gctgacatca agagtatttc cgagaacacc gacagagaca
    16681 acctgcagaa gtgccgtatc cagggcaagt atgccggccg tgtcacagat gtccacaagg
    16741 gcattgtcta tgtgcgcctc tccaatggcg tcaatgcggc agcccattcc tgctatgact
    16801 accggatgcc cggcaaaaag gacgatgtat cttttgctgt cacccgtctg gatatggagc
    16861 ggggtgtggc cgtaggtatt attccccgga tcatccggca gaacctgtaa gcaaatgcgt
    16921 ttatttttca caaaaacaca gttataagct atacaatcaa agatttagga ggcaatttca
    16981 tgcggattca gtttcgtgca gagaattttc tctctatcaa agacagtgtc gtgttatccc
    17041 tctttccagc aaggataacg agcatccaga acatctaatt gtggatggaa gcaaacggta
    17101 tttgaagtct gccgtgattt acggagccaa cgcttccgga aagtccaatg tccttcatgc
    17161 attctggttc atggtaaatt atgtgctgac ttcacataac cagcagctcc acaaagccat
    17221 cgaacgttcg cctttcaagt ttgactgtga aacgccctct cgccccagct gctttgaggc
    17281 catcttcacc gcaaatggca tccgatatgc gtatggcttt tcggtaacag acaaagctgt
    17341 tattgaagaa tacctatatt actatcccaa tggcaggcag gcgatcattt ttgagcggca
    17401 aaacacaaac aattttcgtt ttactgttga tgtcgatgaa caaagcatgc tcaaaaatcg
    17461 tacttcacct aacaagctct atctgtctgt tgcatcaagc tggagctatt ccaaggtaat
    17521 tcctgttctg gagt
//
LOCUS       DBMDUW010000052        17394 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1900_length_17394_cov_3.116637, whole genome shotgun sequence.
ACCESSION   DBMDUW010000052 DBMDUW010000000
VERSION     DBMDUW010000052.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 17394)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 17394)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17394
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1900_length_17394_cov_3.116637"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(84..353)
                     /locus_tag="ACZPCR_09485"
                     /pseudo
     CDS             complement(84..353)
                     /locus_tag="ACZPCR_09485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567505.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(357..1451)
                     /locus_tag="ACZPCR_09490"
     CDS             complement(357..1451)
                     /locus_tag="ACZPCR_09490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006780625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HIR1231143.1"
                     /translation="MNIKTYRNKTLVQNGVTYGIVLACFVLIQVLTAAGGMTSLLKGI
                     LVPLCTYVILAVSLNLTVGILGELSLGHAGFMCVGAFAGAFFTNAVMKTCDIAKNDDQ
                     AVLLLFIGAIVIGALAAAVCGLIIGIPVLRLKGDYLAIVTLAFGEIIKNLINALFVGI
                     DSRGIHFSLKDASSLNLEEGGEVIIKGAQGITGTPKAATFTIGIILVLITLFIVLNLI
                     HSRTGRAIMAIRDNRIAAESVGINITKYKLLAFSVSAALAGVAGVLYAHNLATLAATP
                     KAFGYNMSIMILVFVVLGGIGNIRGSIIAAVVLTLLPELLRGLSNYRMLIYAIVLIAM
                     MLFNSSPKAKELRSRAAASLKKQKKQAKEE"
     gene            complement(1461..2342)
                     /locus_tag="ACZPCR_09495"
     CDS             complement(1461..2342)
                     /locus_tag="ACZPCR_09495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008725457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HIR1231144.1"
                     /translation="MNFLSYLINGISLGSVYAIIALGYTMVYGIAKMLNFAHGDIIMV
                     GGFTAFTVVSTMGGSPIVGILAAVVVCTALGVAVERIAYRPLRDASPLAVLITAIGVS
                     YLLQNVALLIFGSNARQFTSVVNLPPLKLAGGELSISSVTIVTILACVVIMAGLMFFI
                     NKTKIGQAMLAVSEDRGAATLMGINVNRTIAITFAIGSALAAIAGVLLCSAYPSLTPY
                     TGSMPGIKAFVAAVFGGIGSIPGALIGGVLLGVIENLTKAYISSQLSDAIVFSVLIIV
                     LLVRPTGILGKKVSEKV"
     gene            complement(2475..3668)
                     /locus_tag="ACZPCR_09500"
     CDS             complement(2475..3668)
                     /locus_tag="ACZPCR_09500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015513678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIR1231145.1"
                     /translation="MKKRLMSLGLAAVMAMSLTACGNSGSGDGASDSKAADGQEAGAE
                     GEVFVLGGIGPITGAGAAYGESVRNGAELAVKEINEAGGINGYQVEFYFEDDENDAEK
                     SVNAYNTLKDKGMQMLVGTTTSKPCIAVGAESAADNMFQLTPSGSAVQCVENENVFRV
                     CFSDPDQGKKSAEYIADNGLAKKIAIIYDSSSEYSDGIRETFVETAEEKGLEIVASEA
                     FTADSNTDFSVQLDKAKEAGAELVFLPIYYQEASIILKQASDKDFHPMFFGCDGMDGI
                     LSVKNFDQSLAEGLMLLTPFTVDEAGSQDFVAAYEEAYGIEPLQFGAGAYDAVYAIKE
                     AAEKAGVTPDMEVSDMCEAMKTAMTEITIDGLTGEGMTWNANGEPEKAPKAAKIVSGV
                     YEMMD"
     gene            complement(3904..4911)
                     /locus_tag="ACZPCR_09505"
     CDS             complement(3904..4911)
                     /locus_tag="ACZPCR_09505"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006780628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HIR1231146.1"
                     /translation="MASIGVIGAGTWGTALAVLLHSNGHQTAIWSALPEEIEEMTKTR
                     RHKNLPEITIPEEIFLTADLEEAMACKDVLIMAVPSVFVRSTAARMKPFLKKGQLVVD
                     VAKGIEEGTLKTLSQVIEEELPEAETAILSGPSHAEEVSRGLPTTCVVGAHRKETAEY
                     LQSVFMSPVFRVYTSPDMIGIEVGAALKNVIALAAGIADGLGYGDNTKAALITRGIAE
                     ITRLGMKMGGKEQTFVGLSGIGDLIVTCASMHSRNRRAGILIGKGYTMDEAMKEVQMV
                     VEGVYSAKAAKALAEAYGEDMPIVEQINQVLFEGKPAKDAVGDLMLRDKRIENSLLPW
                     D"
     gene            complement(4971..5618)
                     /gene="plsY"
                     /locus_tag="ACZPCR_09510"
     CDS             complement(4971..5618)
                     /gene="plsY"
                     /locus_tag="ACZPCR_09510"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HIR1231147.1"
                     /translation="MERLICLGIGYAFGLIQSGYLYGRSKGLDIRQYGSGNAGSTNVL
                     RVMGAKAGAVVFLGDFFKAVFAMGAAQFLFGHGDGAANSALWAMYAGVGVTLGHNFPF
                     YLHFRGGKGIACLAGILSTMDLRIMVSCMLVFGLAVGITRYVSLGSILVSLVFLAELI
                     FFGSQGSYQVTEACFPEFCILGAFLTFMAIWRHRANIKRLLSGTENKLGAKKKTS"
     gene            complement(5625..6959)
                     /gene="der"
                     /locus_tag="ACZPCR_09515"
     CDS             complement(5625..6959)
                     /gene="der"
                     /locus_tag="ACZPCR_09515"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HIR1231148.1"
                     /translation="MSKKKPIVAVVGRPNVGKSTLFNVLAGEMISIVKDTPGVTRDRI
                     YADGTWLDKNFTLIDTGGIEPDSRDIILAQMREQAEIAIATADVIIFIVDVRQGMTDS
                     DSKVADMLRKSRKPVVLAVNKVDSFAKFGNDVYEFYNLGIGDPIPISATSRLGLGELL
                     DAVIAHFPEQDGEEEDDDRPRIAIVGKPNVGKSSIINKLLGENRVIVSDVAGTTRDAV
                     DTEIVHNGTEYVFIDTAGLRRKSKIKEELERYSIIRTVTAVERADVVLVVIDASEGVT
                     EQDAKIAGIAHDRGKGIIVVVNKWDTIEKNDKTIYEYTNKIKTILSFIPYAEYVFVSA
                     QTGQRLNKLYDLIDMVRENQTMRIQTGVLNEIMTEAVALQQPPSDKGKRLKLYYMTQV
                     AVKPPTFVVFVNDKELMHFSYTRYLENRIRDAFGFRGTALKFIIRERKGKEQ"
     gene            complement(7043..8422)
                     /locus_tag="ACZPCR_09520"
     CDS             complement(7043..8422)
                     /locus_tag="ACZPCR_09520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013272764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HIR1231149.1"
                     /translation="MKKKGHIIKSVDPGSIAEELELEPGDAVLTIDGEEIEDIFDYEY
                     MVNSESITMVVRKADGEEWELDIENNYEDLGLNFENGLMSEYRSCHNKCIFCFIDQMP
                     PGMRETLYFKDDDSRLSFLQGNYITLTNMKDKDFERIIKFHLAPINISVQTMNPELRC
                     RMLNNRFAGEALEKLDRLYEAQIPMNGQIVLCKGVNDKEELNFSIQELTKYIPYMQSV
                     SVVPVGLSKYREGLYPLEPFTAEECGEAIDLIESWQKKIYAEHGIHFIHASDEFYMQA
                     GRPLPEAERYDGYIQLENGVGMIRLMTEEVNEALASLETEQGEREEEISIATGMLPYP
                     YIKEYAEQISRRFPGRTIHVYPIRNDFFGELITVAGLITARDLIAQLKGKELGSRLLL
                     PEAMFRSGEEVFLDDLTRTDVQNALQVPVNIVKSSGRDFVEAVLHPVEDGRDVPEHGP
                     YELNSLEGM"
     gene            8664..9851
                     /locus_tag="ACZPCR_09525"
     CDS             8664..9851
                     /locus_tag="ACZPCR_09525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HIR1231150.1"
                     /translation="MSNDYVFKDRLPVAPLKIAALESCRDLAAKVNEHIINFRRNDAE
                     ELAKRQENLQFRGYDADSYLLNCSCSRFGSGEAKGAVHESVRGTDIYAMVDVTNHSLT
                     YNISGFTNHMSPDDHFQDLKRIIGSTASTAHRVNVVMPFLYEGRQHKRTSRESLDCAM
                     MLEELVNMGVENFITFDAHDPRVQNAIPLNGFDNFMPTYQFVKAIFKHDKTLKIDKDH
                     LMVISPDEGAMNRAVYLANNLGVDMGMFYKRRDYSQVVNGRNPIVAHEFLGSSVEGKT
                     VLIIDDMISSGESMLDTAKALKDRKAAKVLICCTFGLFTNGLEKFDDFYNKGYIDCVI
                     TTNLNYRTPELLKRDWYVEADMSKFIAAIINSLNHNASLENALTSSEKIQQQIRRYNE
                     ANR"
     gene            complement(9957..10916)
                     /locus_tag="ACZPCR_09530"
     CDS             complement(9957..10916)
                     /locus_tag="ACZPCR_09530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HIR1231151.1"
                     /translation="MRGDKNTAEIQSGVQERKDSTKIALVSCSNGMTESFRPSFLRLL
                     SIFEEAGLEPVYGNHLFAGEENPAGQSGRKRAEELMRYYCDPSVDAVFDISGGDIANE
                     ILPWLDFQAIRQKGQGKLLFGYSDLTCVLNAVYGKTGCACGLYQIRNLLHSQGREQLK
                     SLLKLLKEEGRFRGKTSEIHADLDWSQVRPLTDLSVHFLQGESMEGTAVGGNIRCLLK
                     LAGTPYLPDFSGKILILEGNSGGADKMTACLSQLSQMGVFERINGILLGTFTEMERRG
                     DGRRARELVCSFAGELPIAATEEIGHGSGARCAVIGRPLKFGI"
     gene            complement(10952..13006)
                     /gene="recG"
                     /locus_tag="ACZPCR_09535"
     CDS             complement(10952..13006)
                     /gene="recG"
                     /locus_tag="ACZPCR_09535"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006775038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HIR1231152.1"
                     /translation="MEQQPLTSVKGVGDKTARLFSKLGVDTVEELLHYYPRGYDAFRE
                     PQPAGELLPDTMVAVEGTLTKTADVVRFNHLQVVMTHLRDESGTIQLNWYNMPFLRGT
                     LKAGERFVFRGKIMKKRGRLVMEQPEIYRPDKYQELVHSMQPVYGQTKGLGNKTITKA
                     VAEALKTRKLERDFLPERLREKYELAEYNFALEHIHFPGDETELLFSRKRLVFDEFFM
                     FLMSVRLLKEKKSDLESAYVMKRSQESERLKTSLPYSLTKAQEKVLGEVYADLSGGQV
                     MNRLIQGDVGSGKTIIAILALLQAAENGFQGALMVPTEVLARQHLESIEELFAAHGIE
                     KKAVLLTGSMTAKEKRLAYRQIENHEVDIIVGTHALIQEKVVYDKLALVITDEQHRFG
                     VSQREMLGKKGEEPHVLVMSATPIPRTLAIILYGDLDISVIDELPANRKPIKNCVVGT
                     DYRENAYRFIEREVKAGRQAYVICPMVEASEMIEAENVIDYTKTLRENLPAGIRVEYL
                     HGKMKPREKNQLMEDFAAGSIHVLVSTTVIEVGINVPNATVMMIENAERFGLAQLHQL
                     RGRVGRGKEQSYCIMVNASSDKDIQKRLEILNHSNDGFYIASEDLKLRGPGDIFGIRQ
                     SGELEFKLADIFTDAGLLKKVSEEVSQILDEDPALEREDNRELKKRLDAYLEKSYGRL
                     NL"
     gene            complement(13038..14738)
                     /locus_tag="ACZPCR_09540"
     CDS             complement(13038..14738)
                     /locus_tag="ACZPCR_09540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HIR1231153.1"
                     /translation="MGMDYIDAAALKRAFLAGAEGLEARKEWINELNVFPVPDGDTGT
                     NMTMTILSAAREAAAIEEPTMELLAKAISSGSLRGARGNSGVILSQLLRGFAKEIAGK
                     EKIDVACLARAFHRGTETAYKAVMKPKEGTILTVARGMAEKAQELSEETTDILDFVSQ
                     VIEHGDYVLSQTPEMLPVLKQAGVVDSGGQGLMQIVKGCLEGLKGKEAVLGQGAEGTS
                     PAVKVSSSPAADIETADIKFGYCTEFIINLASEFKDSDEKGLKQYLESIGDSLVVVAD
                     DEIVKVHVHTNDPGLALQRALTFGSLSRIKIDNMREEHEERLIKDAERVAREQKEEEL
                     KAQEAQEVSERPRKETGFVAVCAGTGLADIFKGIGADVVIEGGQTMNPSTEDILKAVE
                     QVNADTVYVLPNNKNIILAAEQAKKLSEDCQVVVVPSKTVPQGITALINFAPDLAPQE
                     NLEIMEQEMGRVKTGQITYAVRNTSVDGREIHEGDIMGIGDSGMLAVGSSVSQTAMDA
                     LNAMVDDDSELITIYYGKSVKEEDAENFLEEAREQFSGCEIELHFGGQPVYYYLISVE
                     "
     gene            complement(14759..15115)
                     /locus_tag="ACZPCR_09545"
     CDS             complement(14759..15115)
                     /locus_tag="ACZPCR_09545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HIR1231154.1"
                     /translation="MKGRIDNKYGSIQIDPEVIAMYAGTTAVECFGIVGMAAVSMKDG
                     LVKLLKRESLTKGINVTIRDNAISIDFHVIVSYGVSILAVTDNLIESVKYKVEELTGM
                     TVEKINIYVEGVRVID"
     gene            15346..15531
                     /gene="rpmB"
                     /locus_tag="ACZPCR_09550"
     CDS             15346..15531
                     /gene="rpmB"
                     /locus_tag="ACZPCR_09550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007864321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HIR1231155.1"
                     /translation="MAKCAICEKAAHFGNAVSHSHRRSNKMWKANVKSVKVKVNGGAQ
                     KMYVCTSCLRSGLVERA"
     gene            complement(15674..15811)
                     /locus_tag="ACZPCR_09555"
     CDS             complement(15674..15811)
                     /locus_tag="ACZPCR_09555"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231156.1"
                     /translation="MKRVFGLALFSAGAGMTFILIFPKSFFCVCISAVCLIVGYNLFC
                     S"
     gene            complement(15913..17358)
                     /locus_tag="ACZPCR_09560"
     CDS             complement(15913..17358)
                     /locus_tag="ACZPCR_09560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004606326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HIR1231157.1"
                     /translation="MDLFNKILLDTNNVLTGYVLLIALLGGGIWFTIQTGFVQFREFG
                     NGWRRVFGGLFKKKKNTSKEGGISSFQALTTAIAAQVGTGNLAGAATAIAAGGPGAIF
                     WMWVSALLGMATIFCEATLAQVYRTKGADGKMTGGPVYYIRAAFKGTFGKVLAATFAI
                     LITLALGLFGNAVQANSITDAFHTAFFSNVGSFTLMGQQISYDKIAVGIILAIVAWLI
                     FGGGISRIATITEKLVPIMACFYLLGGLIIVIMNIENVPYMFSAIIRGAFTPQAVCGG
                     AFGVAMKEAVKKGVARGLFSNEAGMGSTPNAHAQAIVDHPCQQGQVAIVSVFIDTMLV
                     LNMTAFVIIGTKMLEPGSAAYVDGKLLEGIALTQTAFTSAFGSFGSIFIAICMLFFAF
                     STILGWYFFGETNVKYLFGEKAVKPYILLVCAFIIIGSLMKVSTIWNMSDCFNSLMVV
                     PNVIALFALTGVVKKTYKDYKENFRPNHPEE"
BASE COUNT         4067 a         4969 c         3795 g         4563 t
ORIGIN      
        1 atttgccgaa gcggaagatc agcttcgtca ggaaataatc aaagcggaag acgagcaaaa
       61 aaacaacgcc aaacttgaat tggccaaata ctacatttct gaaaggttct ggccacccct
      121 gcccggttaa tctcaatatt tttctttccc gcaatgttct ttccgtccag aaggatgatt
      181 cctccgtccg gcttgtacac gcctgtcaaa aggttgaata cagttgtctt tcccgctccg
      241 ttggggccga tgaggccgta aagctggccc ttttcaatcg taatgttaaa atcgtctact
      301 gccttcagtc cgccgaagga gatacttaaa ttttttactt ccagcattgc catatcctac
      361 tcctccttgg cctgtttctt ctgtttctta agcgacgctg cagcgcggct tctgagctcc
      421 ttcgccttgg ggctggagtt gaacagcatc attgcaatca gcacaatcgc ataaatcagc
      481 attctgtagt tgctgagacc gcgcagaagc tccggaagca gcgtcagcac aacggccgcg
      541 ataatggagc cccggatatt tccgattccg cccaacacca caaataccag gatcataatg
      601 gacatgttgt agccgaaggc cttgggcgta gccgccagcg tggccagatt gtgggcgtag
      661 aggacgcctg ccactccggc taaggccgct gatacggaga aggctaagag cttatatttt
      721 gtgatattga ttcccacaga ctcagccgca atcctgttgt ccctgatagc catgatggcg
      781 cgtcccgttc tggagtgaat caggttcagg acaatgaaaa gggtgattaa caccagaatg
      841 atgccgatgg taaaggtagc tgccttaggc gttcctgtga tgccctgggc gccctttata
      901 atcacctctc ccccttcctc taagttcagg gaggaagcgt cctttaagga gaagtggatt
      961 cccctgctgt caattcccac aaacagggcg ttgatcaggt tcttgataat ctcgccgaag
     1021 gccagagtca cgatcgccag gtaatctccc ttcagtctta acacaggaat tccgataatc
     1081 aggccgcaga cagccgctgc cagcgctcca atcacaatcg ctccgatgaa aagcagaagc
     1141 accgcttgat cgtcgttctt ggctatatcg caggtcttca tcacagcgtt tgtaaaaaac
     1201 gctcccgcga aggctcccac gcacatgaag cccgcgtgtc ccagactcag ctctcccaga
     1261 atgcctaccg tcaggttcag ggaaactgcc agaatgacat aggtgcacag aggaaccaga
     1321 attcccttta acaggcttgt cattcctcct gctgctgtca gaacctggat caaaacaaag
     1381 caggccagga caatgccgta tgtaacgccg ttctgaacca gcgttttatt tctgtatgtc
     1441 ttgatattca tggccttcac ctacactttc tcactgactt ttttgcccag aattccagtc
     1501 ggacgcacta acagcacaat aatgagcaca gaaaatacaa tcgcgtctga aagctgggac
     1561 gaaatatacg ccttcgtcag gttctcgatt acacccagaa gcacgccgcc gatcagggcg
     1621 cctggaatgg aaccgattcc gccgaataca gccgccacga aggccttgat gccaggcatg
     1681 gagcctgtgt atggcgttaa ggacgggtat gcagagcaca gcagaactcc cgcaatggca
     1741 gccagggcgg atccgatggc aaaggtgatg gcaatagtcc ggttgacatt gattcccatc
     1801 agtgtagcgg ctcctctgtc ctccgacacg gccagcatgg cctgcccgat cttcgtcttg
     1861 ttgataaaga acatcagtcc tgccataatc acaacgcagg ctaaaatcgt cacaatcgtc
     1921 acgctggaga tagagagctc tcctccggcc agctttaacg gcggcagatt caccacagag
     1981 gtgaactggc gggcgttgga tccgaatatc aggagcgcca cattctgaag caggtagctg
     2041 acgccaatgg ccgtaatcag aacagccagc ggagacgcgt ctcttaaagg cctgtaggcg
     2101 atgcgctcca ccgccactcc aagcgccgta cagacaacga cagccgctaa aattcccaca
     2161 atgggcgatc ctcccatggt gcttaccaca gtaaaggccg tgaagcctcc taccatgatg
     2221 atatcgccat gggcaaagtt cagcatcttt gcaattccat aaaccatggt gtagcccaga
     2281 gcgataatcg cgtagacgct gcccaggctg atgccgttaa tcaaatagga aagaaaattc
     2341 atcatcctcc tacacctcgt tttctttgtt tttactcagt cgaaccggag acagaaaaga
     2401 aggctgccgc actgtgcaac agccctctgt cccatttaca aacagctctg catgcgccgc
     2461 atggggctgc ccttctaatc catcatctcg taaacgccgc ttacaatctt ggctgccttc
     2521 ggagccttct ccggctctcc gttcgcattc catgtcattc cctctccggt cagaccgtcg
     2581 attgtgatct ctgtcatggc tgtcttcatt gcctcgcaca tatcggatac ttccatatca
     2641 ggagttactc ccgctttctc tgccgcttcc ttgattgcat atacggcatc gtatgcgcct
     2701 gcaccgaact gaaggggctc gattccgtaa gcctcctcgt aggctgcaac gaaatcctgg
     2761 cttcctgcct cgtcgactgt gaatggtgtt aagagcatta agccctctgc cagggactga
     2821 tcaaagttct taacgcttaa gattccgtcc atgccgtcgc agccgaagaa cattggatgg
     2881 aagtccttat cggacgcctg ttttaaaata atggaggcct cctgatagta gataggaagg
     2941 aataccagct ctgcgcctgc ttcctttgcc ttatcaagct gtacagagaa gtctgtgttg
     3001 ctgtctgctg taaaagcctc gctggctaca atctccagtc ctttctcctc tgctgtctcc
     3061 acaaatgtct ctctgatacc gtcggagtac tcgctggagc tgtcatagat aatagcgatt
     3121 ttctttgcaa gtccgttatc cgcaatgtac tcggctgatt tcttgccctg atccgggtca
     3181 gagaagcata cgcggaatac gttctcattc tccacgcact gaacggcaga gccggatgga
     3241 gtcagctgga acatattgtc agcggcggac tcggcgccga ctgcgataca cggcttagaa
     3301 gtagtggttc ccactaacat ctgcatgccc ttgtccttta aggtattata tgcgttgaca
     3361 gatttctcag cgtcgttctc atcgtcctca aagtagaact ctacctggta gccgttgatt
     3421 ccgcctgcct cgttaatttc ctttactgcc agctccgctc cgtttcttac ggattctccg
     3481 taagctgctc cggctcctgt aatcggtccg attccgccaa gcacgaatac ctctccctct
     3541 gcgcctgcct cctggccgtc tgctgccttt gaatcagatg cgccgtctcc gcttccggaa
     3601 tttccgcagg cggtcaggga cattgccatc actgctgcca gtcctaaact catcaatctc
     3661 tttttcataa aaaatctcct ccaaaccctc actaaccagc ggttaatgct ttctttttga
     3721 ttgacgccat tatagttttc cgcctgttaa aagtcaatat aaaaacagga gaatttttct
     3781 gttttcagcc tgaaaatgca attttttgca tgattttcag aaatcttatg acttttagtt
     3841 atagcttata ttgtaagaaa ttataatggg ccggcaaggg caggaagaga ttttctattt
     3901 attttagtcc cagggaagaa ggctgttttc aatcctctta tcccgcagca tgagatcgcc
     3961 caccgcgtct ttggcaggct ttccctcaaa cagtacctgg ttgatctgct ctacgatggg
     4021 catatcctct ccgtaggcct ctgccagcgc cttggcagcc ttggcggagt acacgccctc
     4081 cactaccatc tggacttcct tcatggcctc gtccatggta tagccttttc caatcagaat
     4141 tccagctctg cggttccggc tgtgcatgct ggcgcaggtc acaatcaaat cgccgattcc
     4201 agaaaggcct acaaaggtct gctcctttcc gcccatcttc atgcccaggc gggtgatctc
     4261 agcgattcct ctggtgatca gggcggcttt tgtgttgtcc ccatagccca gtccgtcggc
     4321 gattccagct gccagagcga tgacgttttt aagggcggct cccacctcaa tgcctatcat
     4381 gtcaggactt gtgtagacgc ggaacaccgg actcataaag actgactgaa gatattctgc
     4441 cgtctccttt ctgtgggccc ctaccacaca ggtagtgggc agccctcggc ttacctcctc
     4501 cgcatggctg gggccagaaa gaattgccgt ctccgcctcc ggaagctcct cctcaatcac
     4561 ctgggaaaga gtttttaacg tgccttcctc aattcctttg gccacgtcta ccaccagctg
     4621 gccctttttc aggaacggct tcatcctagc tgctgtagag cgcacgaata cagagggaac
     4681 agccataatc agcacgtcct tacaagccat ggcctcctct aaatccgcag tgagaaaaat
     4741 ctcttccgga atcgtaattt ccggcagatt tttatggcgg cgggtctttg tcatctcctc
     4801 aatttcttca ggaagagccg accagatcgc cgtctgatgt ccattgctat gtaacagtac
     4861 agctaacgct gtcccccagg ttcctgctcc gatcacaccg attgatgcca tgattctacc
     4921 tcctcatttc tgtcaagtct tatctattct gctctgtgag aatctgtttc ctaggaggtt
     4981 ttcttcttcg ctcccagctt attttccgtg cctgaaagca gacgcttaat attcgctctg
     5041 tgccgccaga tggccataaa ggtcagaaac gctcccagaa tgcagaattc cggaaagcag
     5101 gcctctgtca cctgatagct gccctggctt ccaaaaaaaa tcagttctgc caagaacaca
     5161 agcgaaacca ggatagagcc taacgatacg tatctggtaa tccccaccgc cagaccgaac
     5221 accagcatac agctgaccat aatccgcagg tccatggtgc tcaaaattcc ggccaggcag
     5281 gcgattccct ttccgccgcg gaaatgcaga tagaagggga aattatgccc cagggttact
     5341 cctactcccg cgtacatggc ccacagagcg ctgttggcag ctccgtctcc atgtccgaac
     5401 agaaactgtg ccgcccccat tgcgaacaca gccttgaaaa agtcccctaa aaatacaact
     5461 gcccctgcct tcgcccccat gacacgaagt acattggtgg agcctgcgtt tccgctgccg
     5521 tactggcgga tatcaagccc ctttgacctt ccgtacaggt accccgactg gatcagcccg
     5581 aaggcgtagc caattcccaa acagataagc cgttccatca tctcctactg ctcctttccc
     5641 ttcctctcgc ggataatgaa tttaagtgcc gttcccctga atccgaaggc gtcgcggatc
     5701 cggttctcca gatatctggt gtaggaaaag tgcatcagtt ccttatcgtt gacaaagact
     5761 acaaaggtcg gcggcttcac ggctacctgg gtcatgtagt agagcttcag tctcttgccc
     5821 ttgtcagacg gcggctgctg cagcgccact gcctctgtca taatttcatt taacacgcct
     5881 gtctgaatcc gcatggtctg gttctctctt accatatcga tcagatcgta gagcttgttt
     5941 aatctctgtc ctgtctgggc agacacaaac acatactccg catacgggat gaaggagaga
     6001 atggtcttga tcttattggt gtactcatag atggtcttgt cattcttctc aatggtgtcc
     6061 catttattga ctacaacgat aattcccttt cctctgtcat gggcaattcc ggcaatcttg
     6121 gcgtcctgtt cggtcactcc ctcagacgcg tcgatgacca ccagcaccac gtcggcccgc
     6181 tccacggcag ttacagtacg gataatgctg tagcgctcca gttcttcttt aatcttgctc
     6241 tttcttctga ggcctgccgt atcgataaac acatactctg tgccattgtg cacaatctcc
     6301 gtatccacag cgtctctggt agttcccgcc acgtcggaca caattacacg gttctcccct
     6361 aacagcttat tgataataga agattttccc acgttaggtt ttcctacgat ggcgattctc
     6421 ggcctgtcgt cgtcctcctc ttccccatcc tgttccggga agtgggcgat cactgcgtct
     6481 aacaactctc ccagccccag gcgggaggta gctgaaatcg ggatgggatc tccgattcca
     6541 aggttataga actcgtagac gtcgtttcca aacttggcga agctgtccac cttattgact
     6601 gccagaacta ctggttttct ggactttctc agcatgtcgg ccacctttga gtcagagtct
     6661 gtcatgccct ggcgcacgtc cacaataaag ataatcacgt ctgcagtggc aatggcaatc
     6721 tccgcctgct ctctcatctg ggccagaata atatctctgg aatccggctc gattccgccg
     6781 gtgtcaatca gggtaaagtt cttgtccagc caggttccgt cagcgtagat acgatctctg
     6841 gtcactccag gcgtatcctt tacaatggaa atcatctcgc cggccaggac gttgaacagc
     6901 gtggattttc ccacgttagg acggcctacc acggctacga tcggtttctt tttgctcata
     6961 ttcattcctc cattaaaggg cggcatcctg cagttccaga ataccgtccc atatttttcc
     7021 tgcaagctct ttggcagggc gtctacatcc cttccaaaga gtttaattca tacggcccgt
     7081 gttccggcac gtctcttcca tcctccaccg gatgaagcac tgcctccacg aaatcacgtc
     7141 cgcttgattt tacaatattc actggtactt gtaaagcgtt ttgtacgtct gtcctggtca
     7201 gatcgtccag gaaaacctcc tccccgcttc ggaacatggc ctccggaaga aggagacggc
     7261 ttcccagctc ttttcccttc agctgggcaa tcaggtctct ggctgtaatc agcccggcca
     7321 ccgtaatcag ctctccgaaa aagtcgttcc tgatggggta cacatggatc gttctgcccg
     7381 gaaaacgcct gcttatctgc tcagcatact ccttaatata aggatagggg agcatgcctg
     7441 ttgcaatgga gatctcttct tcccgttccc cctgctctgt ctcgagcgaa gccagggcct
     7501 cgtttacctc ctctgtcatc agacgtatca tgcccactcc gttttccagc tgaatgtagc
     7561 cgtcgtaccg ctctgcctcg ggaagaggac gccctgcctg catatagaac tcgtcgctgg
     7621 catggataaa gtggattccg tgctccgcat aaattttctt ctgccagctc tcaatcaggt
     7681 cgatcgcctc gccgcactcc tccgccgtaa aaggctccag gggatacagg ccttccctgt
     7741 attttgacag tcccaccgga actacagaca cgctctgcat atagggaata tactttgtca
     7801 gctcctgaat ggaaaaattc agctcctctt tgtcattcac tcccttacag agaacaatct
     7861 ggccgttcat ggggatctgg gcctcataca gccgatccag cttctccagt gcctcccctg
     7921 cgaaccggtt gttcagcatc ctgcaccgaa gctccgggtt catggtctgg acggaaatat
     7981 tgatgggcgc cagatggaac ttgataatcc tctcaaaatc cttgtccttc atattggtca
     8041 aagtaatgta atttccctga aggaaggaca gtctggaatc gtcgtcctta aaatagaggg
     8101 tttctctcat ccccggcggc atctggtcaa taaaacagaa gatacattta ttatggcagg
     8161 aacggtactc gctcatcagt ccgttttcaa aattcagccc taaatcttca taattattct
     8221 caatatccag ctcccactcc tcgccgtccg cctttctcac caccatggta atggactcgc
     8281 tgttcaccat atactcatag tcaaaaatat cctctatctc ttccccgtct atggtgagca
     8341 ccgcgtctcc cggctctaac tccagctcct ctgcgatgga acctggatcc acagatttaa
     8401 tgatatgacc ttttttcttc atggtctgcg tctgcctttc tatttttctg aaatccggcg
     8461 gtctggttcc gccttcgtct tacacttctt ttatcatatc aacattagct gagtttgtaa
     8521 agaactggac gcaggttgtc tttttcaggg attttccggg aatttcggca tttactattg
     8581 acggttcctg tctaaaaatg gtataaaaat ggtgcaaaga ctgctgacag gacatccctg
     8641 tctgataaat ggaggaattt tctatgtcga acgactatgt atttaaggac cgtctcccgg
     8701 tagcgccttt aaaaattgcc gcactggaga gctgccgcga tctggctgcc aaggtcaacg
     8761 aacacatcat taactttcgc cgcaacgacg ctgaggagct tgcaaagcgt caggaaaatc
     8821 ttcagttccg cggttatgac gctgattctt acctgttaaa ctgctcctgc tcccgtttcg
     8881 gaagcggcga ggccaagggc gctgttcatg agtccgtccg cggaaccgat atctacgcta
     8941 tggtagacgt gacaaaccac agcctgacct acaacatcag cggatttaca aaccacatgt
     9001 ctccggacga tcatttccag gatttaaaga gaattatcgg atccactgcc tccaccgcgc
     9061 accgcgttaa cgtggtaatg cctttcttat acgaaggaag acagcacaag agaacgtcca
     9121 gagagtcctt ggactgcgct atgatgttag aagagctggt gaacatggga gtagagaact
     9181 tcatcacctt tgacgcccat gatccgagag tgcagaacgc aatcccgtta aacggatttg
     9241 acaacttcat gccaacctat cagtttgtaa aagcgatttt caagcacgac aagaccttaa
     9301 agatcgacaa ggatcatctg atggttatca gcccggacga gggagctatg aaccgcgccg
     9361 tttaccttgc caacaacctg ggcgttgaca tgggtatgtt ctacaagcgc agagattact
     9421 ctcaggtagt caacggcaga aacccaatcg tagcccacga gttcttaggc tcttctgtag
     9481 aaggaaagac tgtccttatt atcgacgata tgatttcctc cggcgagagc atgctggata
     9541 cagccaaggc cttaaaggac agaaaggcag ccaaggttct catctgctgc accttcggtc
     9601 tgttcacaaa cggtctggag aaatttgacg atttctacaa caagggctac atcgactgtg
     9661 tcatcaccac aaacttaaat tacagaacgc cggagctgtt aaagcgcgac tggtatgtgg
     9721 aggctgacat gagcaagttc atcgcagcga ttatcaactc cttaaaccac aacgcttccc
     9781 tggagaacgc gctgacctcc tctgagaaga ttcagcagca gatcagaaga tacaacgaag
     9841 caaaccggta ggaaacgcca tttatcagat gttttaaatt gaaaaagaca gtgtttttgt
     9901 tccgccaagg tcacaaaaaa cactgtcttt ttcttttcat ataagccgca gcaaaactag
     9961 attccaaatt taagcggcct tcctatgacc gcgcatctgg ccccgcttcc atgacctatc
    10021 tcttctgtgg cggcaatggg aagttccccg gcaaaagagc acaccagctc tctcgccctt
    10081 ctcccgtccc ctctgcgttc catctctgta aaagttccca gaagaattcc atttatccgt
    10141 tcaaacactc ccatctgtga cagctgggac aggcaggcgg tcattttatc ggcgccgccg
    10201 ctgtttccct ctaaaatcag aattttcccg gaaaaatcag gaagatacgg agtcccggcc
    10261 agctttaaca ggcagcggat gtttcctccc acagctgttc cctccataga ctcgccctga
    10321 agaaaatgaa cgctcaaatc cgtcaggggg cgaacctgag accagtccaa atccgcatgg
    10381 atttccgacg tttttccccg aaatctgccc tcttctttca aaagtttaag aagacttttc
    10441 agctgttccc ttccctggga atggaggaga ttgcggatct ggtacagacc gcaggcgcag
    10501 ccggtttttc catagactgc gttcagcaca caggtcagat cgctgtatcc aaacagcagc
    10561 tttccctgtc ccttctgcct gatcgcctgg aagtccagcc acggcagaat ctcatttgct
    10621 atatcgcctc ctgaaatatc aaacacagcg tccaccgacg gatcgcagta atatctcatc
    10681 agctcttccg cccgctttct gccgctctgt cctgccgggt tctcctcccc tgcaaacagg
    10741 tgatttccgt acaccggttc cagtcccgct tcctcgaaaa tcgaaaggag ccgtaaaaag
    10801 gacgggcgga aggactctgt catgccgttg gaacagctga ccagggcaat tttcgtactg
    10861 tcttttcgtt cctgtacacc gctctgaatc tctgccgtat ttttatcccc tctcatccgc
    10921 cttttcctcc ttttcttctg cttatttcag gctacagatt cagcctgccg tagctttttt
    10981 ccagatacgc atccagccgc tttttaagct ctctgttatc ctcccgctca agagccggat
    11041 cctcgtctaa gatctggctg acctcctcag acaccttttt cagaagacct gcgtctgtaa
    11101 aaatatcggc cagcttaaat tccagctctc cgctctggcg gattccgaaa atatcgcctg
    11161 gcccccgcag cttcaaatct tcggaggcaa tgtaaaatcc gtcgttggag tggttgagga
    11221 tctccagacg tttctggata tccttgtcag aagaagcgtt taccatgatg cagtaggact
    11281 gctcttttcc gcgtcctacc cggccccgca gctgatggag ctgggccagg ccgaaccgct
    11341 ccgcgttctc aatcatcatc accgtggcgt ttggaacgtt gatccccacc tcaatcaccg
    11401 tagtggacac aagcacatga atgctgcctg cggcgaaatc ctccatcagc tggtttttct
    11461 ccctgggctt catctttcca tggagatatt ccacccggat cccggcaggc agattctcgc
    11521 ggagagtttt cgtgtagtct atgacatttt ccgcctcgat catctcgctg gcctccacca
    11581 tagggcagat cacgtaggcc tggcggcctg ccttcacctc ccgctcaata aaccgatagg
    11641 cgttctctct gtaatctgtc cccaccacac agtttttgat aggctttctg ttagccggaa
    11701 gctcatcaat cacagaaata tccagatcgc cgtagagaat aatggcaaga gttctgggaa
    11761 tgggcgtggc gctcatgacc agtacatgag gctcctctcc cttcttcccc agcatctccc
    11821 tctggctgac gccgaagcgg tgctgctcgt ctgtaatgac aagagccagc ttgtcataga
    11881 ccaccttctc ctgaatcaga gcatgggttc ccacgataat atccacctcg tggttttcta
    11941 tctgccgata ggccaggcgc ttctcctttg ccgtcatgga tcccgtcagt aaaaccgcct
    12001 ttttctcaat gccgtgagct gcaaacagct cctcgatgga ttccagatgc tgtcttgcca
    12061 gtacctctgt gggaaccata agcgcaccct ggaagccgtt ctccgccgcc tgcagaagag
    12121 ccaaaatggc aatgatcgtc tttccggagc ctacgtctcc ctgaatcaac cggttcatca
    12181 cctgaccgcc ggataaatcc gcatagacct cgcccagcac cttctcttgg gcttttgtca
    12241 gggaatatgg cagagaagtc ttcagcctct ccgattcctg actccgcttc atcacatagg
    12301 cgctttccag atccgacttt ttctctttca gcagacggac cgacatcaga aacatgaaaa
    12361 attcgtcgaa aaccagccgt tttctcgaaa aaagcaactc cgtctcatcc cccggaaaat
    12421 gaatgtgttc cagcgcaaaa ttatactctg ccagctcata tttttcgcgg agacgctccg
    12481 gcagaaagtc tctctccagc tttctggttt taagagcttc tgccactgcc ttggtgatgg
    12541 tcttattccc aaggcctttt gtctgtccgt agaccggctg catggagtgg accagctcct
    12601 gatacttgtc aggtctgtag atttccggct gctccatgac cagccgcccc cgctttttca
    12661 tgatctttcc gcgaaagaca aaccgctccc cggcctttaa ggttcccctg agaaaaggca
    12721 tattgtacca gttcagctga atggttccgc tctcatctct caggtgagtc atcaccacct
    12781 gcagatggtt aaagcgcact acgtctgccg ttttcgtcag agtcccctcc actgctacca
    12841 tagtatccgg cagcagctct cccgctggct gcggctcccg aaacgcgtcg tagcctctgg
    12901 gatagtaatg aagcagttcc tccaccgtat ccaccccaag ctttgaaaac agcctggcag
    12961 tcttatctcc cacgcctttc accgatgtca gcggctgctg ttccatgccc tctcctcctg
    13021 gttttccctt tcttaattta ttccacagaa atcagatagt agtaaactgg ctggcctccg
    13081 aaatgaagct cgatctcaca gccggaaaac tgctccctgg cttcctccag gaagttttct
    13141 gcatcttctt ccttcacact ctttccatag taaatggtaa tcagctctga atcgtcgtct
    13201 accatggcgt tcagcgcgtc catggccgtc tggctcacac tgctgcctac tgccagcatg
    13261 cctgagtcgc cgattcccat aatatctccc tcatggatct ctcttccatc tacagaagta
    13321 tttctgactg cataagtaat ctggccggtt tttacgcgtc ccatctcctg ctccataatc
    13381 tccaggtttt cctggggtgc cagatccggc gcgaaattaa tcagggccgt gattccctga
    13441 ggaaccgtct ttgacggaac aaccacaacc tggcagtcct ctgaaagctt cttcgcctgt
    13501 tctgctgcca gaataatatt tttattgttg ggaagcacat agacggtatc tgcgttgacc
    13561 tgttccacag cctttaaaat atcttctgtg ctgggattca tggtctgacc tccctcaatc
    13621 accacatcgg ctccaatgcc cttaaaaata tcggccagcc cggttcctgc gcagactgcc
    13681 acaaaacccg tttcctttct cggtctctct gagacctcct gggcctcctg agcctttaat
    13741 tcctcctctt tctgttccct ggccacgcgc tccgcgtcct tgatcagcct ctcctcgtgc
    13801 tcctctctca tattgtcaat cttgattctg gagagggagc cgaaggtgag cgctctctga
    13861 agcgcaagcc cgggatcgtt ggtgtggaca tgcaccttta ctatctcgtc gtccgctacc
    13921 actacaagag agtctccgat agattccaga tactgtttca gtcccttttc gtcagaatcc
    13981 ttaaattcag atgcaagatt aatgataaac tctgtgcagt aaccgaattt aatatcagcc
    14041 gtctcaatat cagctgccgg tgaactggaa acctttacag caggcgaagt tccttctgcg
    14101 ccctggccaa ggaccgcttc cttccccttc aggccctcca ggcatccctt cacaatctgc
    14161 atcagcccct ggccgccgga atctaccact cccgcctgct tcagaaccgg gagcatctcc
    14221 ggcgtctggc tgagcacata atcgccgtgt tcaatcacct gggacacaaa gtccagaata
    14281 tccgtggtct cctctgaaag ctcctgggcc ttctccgcca tacctctggc aacagtgaga
    14341 atggttccct ccttcggctt cataaccgcc ttgtaggcag tctctgtacc tctgtgaaag
    14401 gctctggcca ggcaggccac gtcaatcttc tctttgcctg cgatctcttt tgcaaagccc
    14461 ctcagaagct gagaaagaat gactcctgaa tttcctctgg cccctctcag agagccggag
    14521 gagatcgctt tcgctaaaag ctccatcgta ggctcctcga tggccgcagc ctctctcgcg
    14581 gcagagagaa ttgtcatcgt catattcgtt cccgtatctc cgtcaggcac cggaaataca
    14641 ttcagttcat taatccactc ttttctggcc tcaaggccct cagcgcccgc gagaaacgct
    14701 cgtttcagcg ccgcggcgtc aatatagtcc atacccacag gttgtttcct ccttatgatt
    14761 aatcaatcac ccgtacgcct tcaacgtaaa tgttgatttt ttctaccgtc atgccggtca
    14821 gctcttccac tttatacttc acgctttcaa tcaggttatc cgtcacagcc agtatgctga
    14881 ctccgtagga cacaatcacg tgaaaatcaa tgctgatcgc attgtcccgg atcgttacat
    14941 tgatgccctt tgtcaggctt tcccgtttta aaagctttac cagaccgtct ttcatactga
    15001 cagcggccat tccgacaatt ccaaaacact ccactgccgt cgttcccgca tacatcgcaa
    15061 tcacttccgg atcaatctgg atcgaaccat atttattgtc aatacgcccc ttcatagctg
    15121 cagcctccat tcttttttcg ttttgagatt cccgactgtc actgccaggc acagaagatc
    15181 tccctctcgt ttcgagacct cctggttatt agtaattata ccttattttt gtaaaaaaag
    15241 aaacaaaatt ttatttttca cttgcaaatt tgcccgcttt ctgctatcat acagttgtta
    15301 tggattttta cgcaaaatcc gatgaacggt agaggaggtg caaccatggc taaatgtgca
    15361 atctgtgaaa aagctgctca ctttggtaat gcagtaagtc attcccatag aagatctaac
    15421 aaaatgtgga aagctaatgt taagtctgtt aaagttaaag taaacggcgg agctcagaag
    15481 atgtatgtat gtacttcttg cttaagatcc ggtttagttg agagagcata attatcgtgc
    15541 ggttcagcgt gtaaaagagg agataaaatc aggcctggtt ttatctcctc ttttcttgtc
    15601 tgcttttcta tttttttcat atcagtccga cttttaaccg ttcatcattt ccctgtatct
    15661 ttttcaaatc gtttcagctg cagaacaggt tgtagccgac aattaaacac acagctgaaa
    15721 tgcacacgca gaaaaagctc ttcggaaaaa tcaaaataaa cgtcattccg gctcctgccg
    15781 aaaacagcgc taagccaaat acccgtttca tgcgaagccc tccctggctg cgcccgcaaa
    15841 aaaaccaggc gcctgtatac tatatcgtat gcagacgcct ggttttcatt ctcttcctat
    15901 atgtaattta ctttactctt ccgggtgatt cggacggaag ttttctttat aatctttata
    15961 tgttttcttt acaactcctg tcagtgcgaa cagagcgatt acgttcggaa cgaccatcag
    16021 agagttgaag cagtcggaca tattccagat agtagaaacc ttcatcagag aaccgatgat
    16081 aatgaacgcg catactaaca gaatgtacgg cttcactgcc ttctcgccaa agaggtattt
    16141 tacgttggtc tcgccgaaga aataccatcc aaggattgta gagaaagcga agaacagcat
    16201 acaaatcgcg ataaagatag aaccaaagga accgaatgca gaagtaaatg cggtctgtgt
    16261 cagagcgatt ccctctaaga gcttgccgtc cacataagct gcagaacctg gctcaagcat
    16321 ctttgttccg atgataacga atgctgtcat gtttaatacc agcatagtat caataaatac
    16381 agatacgata gctacctggc cctgctggca cggatggtca acaatcgcct gagcgtgagc
    16441 gtttggtgtg gaacccatac ctgcctcgtt ggagaacaga cctctggcaa cgcccttctt
    16501 tacagcctct ttcatagcta cgccgaacgc tccgccgcat acagcctgag gtgtgaacgc
    16561 tccgcggata atagcggaga acatatacgg tacgttctca atattcatga taacaataat
    16621 cagtccgcct aacagataga agcatgccat aatcggaacc agcttctctg tgatagtagc
    16681 gattctggag ataccgcctc cgaaaatcag ccatgcaaca atcgcaagga tgattcctac
    16741 agcaatctta tcataggaaa tctgctgtcc cataagtgtg aagcttccta cgttagagaa
    16801 aaatgctgtg tggaacgcgt ctgtgatgga gttggcctga actgcgtttc caaacagtcc
    16861 gagagccagg gtaattaaaa tcgcgaacgt cgctgccaga acttttccaa atgttccctt
    16921 aaaagctgcc cggatatagt aaacagggcc tcctgtcatc tttccatcgg ctccctttgt
    16981 tctgtacacc tgagccaggg tcgcctcaca gaaaatggtg gccatgccca gaagagcgga
    17041 tacccacatc cagaaaatcg ctccgggacc gccggctgca atggctgtag ccgcgccggc
    17101 caggtttcct gtacctacct gggctgctat cgctgttgta agagcctgga aagaagaaat
    17161 tccgccttcc ttgctggtgt tcttcttctt tttgaacaat cctccgaata ctctgcgcca
    17221 tccgtttcca aattcccgga actgtacaaa gcccgtctga atggtaaacc agattccgcc
    17281 tcccagcaaa gctatcagca gaacataacc agtcagtaca ttattggtgt ccagaagaat
    17341 tttgttgaat aaatccatac gctgccttcc cccttcgtgg tattattcga attg
//
LOCUS       DBMDUW010000053        17245 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1921_length_17245_cov_3.386724, whole genome shotgun sequence.
ACCESSION   DBMDUW010000053 DBMDUW010000000
VERSION     DBMDUW010000053.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 17245)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 17245)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17245
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1921_length_17245_cov_3.386724"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..1714
                     /locus_tag="ACZPCR_09565"
     CDS             <1..1714
                     /locus_tag="ACZPCR_09565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231158.1"
                     /translation="NFLVFLILCILIFLVVNFLSYTKDFLQTLGSGRGVQMVKDEETG
                     QFVFRRNSGKRSGVSLGRPLKYGFIAIGLIIILMTVASLLGLQFFNATRYRDLITIED
                     GDFAQDVAELNMSQIPVVDKDTASRLGSRKLGEMTELVSQFEIQDDYTQINYKGSPYR
                     VTPLRYADPIKWLFNHKEGLPAYLTVDMVTQETNLVWLENGMRYSPSEYFFRNIYRYI
                     RFKYPTKMFETVSFEIDDNGTPYWIAPTISYRIGWWDGKDIDGAVLVNAVTGESEWYA
                     KEDVPQWVDQLYYAELLIGQLDDNGRFQHGYINSVFGQKDVRRTTYGYNYMAINDDVY
                     LYTGMSSVTADESNIGFVLVNCRTKETKFYTVPGATETSAMASAQGQVQHLNYSATFP
                     LLLNISNRPTYFLSLKDNAGLVKMYAFVDVEQYQIVGTGQTIDEAKSNYRKALNLEDV
                     EVQELVDSTEISGTVASLASAVVSGNTCYYFTLEGDSQVYTASVDIHEKLPFMQPGAE
                     LSFSYAEDGAVRRVTEVHELALPDSGDISSQTEAPEADSIQPETSEEVSPADSEAGQP
                     ADGQ"
     gene            1729..2739
                     /locus_tag="ACZPCR_09570"
     CDS             1729..2739
                     /locus_tag="ACZPCR_09570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HIR1231159.1"
                     /translation="MKSDDIIMKTGIVHILDSSVGVPVLSDCPIDLSGDLSEFLKAHI
                     EKLTESDDVKLCRFGNDSPVKQLLEQCTPETFVETSKQLAQLLYDIMNANIDIPPADV
                     AVVVFSSGGSDYLALLKMNYKTSYTHLTKEQEGKNANSIILQKALLPGQGQKLSEAFV
                     VNLGTGELLVTEKKYEVNGEKRLYFSELYLECHAPLSQKSKLDIVTRAVEQVNRKYYG
                     DDDAERKMEIKNVIYKELEEEGAIKVESLREKVFPDSPEMQTAFDEKMEKYNLSYETV
                     QPKNEQTVKKFQSQRLTTDTGIEITIPMEEYQNPDRVEFITNPDGTISVLIKNIGHLM
                     SK"
     gene            complement(2883..3695)
                     /locus_tag="ACZPCR_09575"
     CDS             complement(2883..3695)
                     /locus_tag="ACZPCR_09575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231160.1"
                     /translation="MSFILCRQEEVTHPLYIEALGVHIWSSQELCYVIYNYPLLAMDH
                     FLDERLTEFIEKELRMTVLAARLENGLRTGADEDELIFMFLEECHFYSPKEITAFRQK
                     ISSYRNMGSLEFAKATADYYYTLRQYGTALRGYEKLLDSQHNKAADDEFLGKVWNNMA
                     ACYAGLFWFDKAMQAYEMSWSYRKDPDTVKRMYHLTLLNPKLSVKARFGAGLLDSRKE
                     QWKEEFEEAVSRARHSESVRQAEELFNQEKTARRQAEGELLSRWKAGYRAMI"
     gene            complement(3692..4912)
                     /locus_tag="ACZPCR_09580"
     CDS             complement(3692..4912)
                     /locus_tag="ACZPCR_09580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5716 family protein"
                     /protein_id="HIR1231161.1"
                     /translation="MDGLVLGVDLCDTYTSITALEPERTWTIKTAVCKNRQSEEWYVG
                     EEASARAMAGDPHWDSLLSRIQRDEKEPERENGYTGLDLLKRFLKEALELPKKEAEKE
                     EISRLVIALRKPEIRLMDSLLYCADYLGIDRSRVHIVSHTESFVYYVMSQKRDVWSNQ
                     VGMFELSEGCARYYELKTQRGSRGMIVTADREDLQEEITLEYLKRPEGAASEDQFLAA
                     CADRILDKRLFSAVILTGDGFATTDWAHSFMKKICSKRRVFAEYGLFSKGAAYRGADY
                     ERERTDYPFTCICEGRLQYTISLQVLNRGKDTSLVLAAAGDNWYEARSTVDLIADGED
                     HLEFVISSLDQRKRRVVPVALQDFPIRENKTNRIQVTIGFSDESTMIIMVRDKGFGEL
                     FPASKAMVRQEVVL"
     gene            complement(5000..8701)
                     /locus_tag="ACZPCR_09585"
     CDS             complement(5000..8701)
                     /locus_tag="ACZPCR_09585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5717 family protein"
                     /protein_id="HIR1231162.1"
                     /translation="MRERINRLAMGIVDTSKPKVIWTPDAIEETIRTNTTVRRELFIG
                     TEGGGSVKGLAYSTSDRVRIFADHASFGGVRNRIAYEVDTSFMEAGDEIDGMFNLVTS
                     CGEIEIPYVFYVDLAASGSVLSSLKTPEDFARLAGRDGDTALRLLDYPDFAEAPFMQD
                     PHVRAVYEGLKGHGSRQCFLEEFLNGLGVKEPFCIFFDEEQKTYENPSGHIQDSIEIK
                     SRGWGYICLEAEADGDFIHLLKRTVTQEDFKNGACSLPFQILSENLHGGRNYGAVFVT
                     AAGETHKISISVTVGGEKAQKSISFRENLRNYMELRLQYEALAEPSYESGGEGEEDQE
                     ENQTRQTGRKKKKPEVKDERTLSQRRLASSMGRLLSQMKISYEDSAVRLLEAEHLLAV
                     GRRDRAQAILDSVREQILAERDSRVMNYLLFQYIQVSLSGDEAQRDALLRLLRRHLAA
                     EPGNFYLYMMILRLDPELAASPAAVYADLRRQFREGAASPFLFLEACRILAREPEFLR
                     NMEPFESHVIYFGARRGLLSEETALAAADVIDRKKEFWPFGLKILTALYAQFENTEIL
                     SAVCAMLIRGGCREQKYFSWYEKGVEAKLALTKLYEYYLYCLPENYEKPLSREMLLYF
                     SYGNELNEKGKARLYRNVLEFYRDDESMFRFYEREIEKFALSQLFAGKISRDLAVIYK
                     TVIYPDVVDRQLARVLPSVLKSNCITVKDSRIRYVILRHEELTTEDAYPLTEQTAYVP
                     LFSSRDILMFQDEAGNRFMSTPYETSAAMEEEELAKRCFQVYPEHTSLLLNACQRALD
                     REEKERAGAVGSMTENEEEILVKALSEPSLHPIYRKKIMSALIRRYVDSLALGGQGDR
                     ERAAAFLLAADKDSISPDERAQIMKALIAQGCYSEAYDMLCRYGSERLETAELKKLVV
                     KMLLESLMREDERLLNLSFQIFQEGRADGAILSYLCEYFNGTVDQMFCILLAAVRDQA
                     DTADMEERLLCQMLFTGCTEKIDRVFDLYASRKKTREMIVKAYFTVKCIEYFMEEKPA
                     QDKVFAYLEGAVYNSSDRDRIPDIYLLALTRYYASLPSLTKEQEELCRAVTEVLLEAG
                     MEFAYFKELSRFAAVPERLLDKEMIEFHGEKDSDPVLMVRVLPEEQEFVCEEMKEVYK
                     GIFVREKVVFEGEVLEYQIYRKRGDQAPAVSGSLERREPPVKQEGTRFALLNQMGLSF
                     DMKNENTLRSQMEEYLTADAVSQALFGLL"
     gene            8880..10031
                     /locus_tag="ACZPCR_09590"
     CDS             8880..10031
                     /locus_tag="ACZPCR_09590"
                     /EC_number="1.1.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004471 - malate dehydrogenase
                     (decarboxylating) (NAD+) activity [Evidence IEA];
                     GO_function: GO:0004473 - malate dehydrogenase
                     (decarboxylating) (NADP+) activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent malic enzyme"
                     /protein_id="HIR1231163.1"
                     /translation="MTNSEKALKLHEEWNGKIETVSKAAVKSREDLALAYTPGVAEPC
                     KVIAENPEAAYTYTIKSNTVAVVSDGSAVLGLGNIGPLAAMPVMEGKAVLFKEFGGIN
                     AFPICLDTQDTEEIIETVVRIAPAFGGINLEDISAPRCFEIEERLKERLSIPVFHDDQ
                     HGTAIVVLAGIINALKVTGKKKETAQVVVNGAGSAGIAITKLLLTYGFQNITLCDKAG
                     MICEGMEGLNWMQEKMAKVTNLGKRTGSLADALKSADIFVGVSAPGIVTPEMVASMNH
                     DAILFAMANPVPEIMPDLAREAGARVVGTGRSDFPNQVNNVLIFPGIFRGALEGRACA
                     ITEEMKLAAAEAIASLVSEEELSDVNILPAAFDPRVADAVSQAVKEHIR"
     gene            10069..10605
                     /locus_tag="ACZPCR_09595"
     CDS             10069..10605
                     /locus_tag="ACZPCR_09595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HIR1231164.1"
                     /translation="MLAEPMTLYKLMNLYMLKQVNFPLTNAQLSSFFLDRDYTSYFTL
                     QQALNDLLDAGLIRQETVHNSTRYEITPEGEDTLDFFGKTISPAIVEDMNEYLKENKF
                     RMRDEAGFISDFYKSTNQDYTVHCEVREGKNVLISLDVSVPDKEQAESMCNHWKGKSQ
                     EIYSFIMKSLMSDKPVKP"
     gene            10632..10844
                     /locus_tag="ACZPCR_09600"
     CDS             10632..10844
                     /locus_tag="ACZPCR_09600"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231165.1"
                     /translation="MFRTRTKPEPVRLRDLIRGDFSQARRRYQMFKRKCFIFLFLPAA
                     VFAILNRAAEEYAKIKALQEKNARRP"
     gene            complement(10948..12138)
                     /locus_tag="ACZPCR_09605"
     CDS             complement(10948..12138)
                     /locus_tag="ACZPCR_09605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002577955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIR1231166.1"
                     /translation="MFHLLLGIIYLAFISLGLPDSLLGSAWPVMYREFSVPVSYAGVI
                     SMIISAGTIFSSLQSDRLTRQFGTGRVTAASVCMTAVSLLGFSTSGSYLELCLWAVPY
                     GLGAGSVDASLNNYVALYYTGSHMSWLHCMWGVGASLGPYIMGAALEGGHGWNMGYRC
                     IAVLQFALSAVLAASLPLWKKRRASGEKAACLSTEAGRRPLSIGGIVRLPGAKEILAA
                     FFCYSALEQTAGLWAGSYLVLCRGISAEAAAGFVSLFFLGITAGRAISGFLTMKLGDT
                     RMIRLGEAVIFLGILCLFLPFGSRAASAGLILTGLGCAPVYPSIIHSTPEHFGADKSQ
                     AVIGVQMAFAYVGSLSMPPLFGVIASHAGAALFPVFLIVILALMAVLHEKMLASVRGG
                     KHKK"
     gene            complement(12138..12734)
                     /gene="yihA"
                     /locus_tag="ACZPCR_09610"
     CDS             complement(12138..12734)
                     /gene="yihA"
                     /locus_tag="ACZPCR_09610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014078828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HIR1231167.1"
                     /translation="MIIKKVDLETVCGITSKLPANTQPEFAFAGKSNVGKSSLINALM
                     NRKAYARTSAQPGKTQTINFYHINDAFYYVDLPGYGYARANQEVKAKWGKMIENYLHK
                     SPMLKCVFLLIDIRHDPSENDRLMYQWILDQGYRPVIIATKADKLKRSQIAKHVKMVR
                     EGLSMQPEDVLIPFSAETKQGREEIWDYIEKTAAEEEQ"
     gene            complement(12786..>15043)
                     /gene="lon"
                     /locus_tag="ACZPCR_09615"
     CDS             complement(12786..>15043)
                     /gene="lon"
                     /locus_tag="ACZPCR_09615"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: protein motif:HMM:TIGR00763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HIR1231168.1"
                     /translation="NPQAEDLYQMGTIAMVKQLVKLPGGVIRVMAEGEERAELLSLNA
                     DGSYLEGEAEIRATEEENLGQVEKEAMIRIVKEKLEEYGRVDQTAAREILPNLLAITE
                     LPELLNQTAVQFPWEYTVKQQVLDQVYLTGQYEQIVSILLTEIEVFQVKKEFQSKVKA
                     AIDKNQKDYILREQMRIIREELGEDNPMSDADELKEKLASLKAGKEVKDRIAKEIERF
                     KGMPGGSQDANVLRTYLETVLELPWDKVTRDNNDLRHAEEILNEDHYGLEKVKERVLE
                     YLAVRILTKKGTSPIICLVGPPGTGKTSIARSVARALGKKYVRISLGGVHDEAEIRGH
                     RKTYVGAMPGRIVEGLKQAGVKNPLMLLDEIDKVSSDYKGDTSSALLEVLDSEQNVKF
                     RDHYVEIPVDLSEALFIATANTTQTIPGPLLDRMEVIEVSSYTENEKFHIGKNYLIPK
                     QMERHGLTKKDLSVSGAALEKIIHNYTREAGVRNLERRIGDICRKAAREILEEQMREK
                     SRQKTKSLKAAEIKTEKADKKAGKEKAGHEKTIRVTEKNLEKYLGREKIQFEDACETD
                     QVGIVRGLAWTSVGGDTLEIEVNVMPGKGVLQLTGQMGDVMKESAQTALSYVRSAADQ
                     YGVKNSYFEKHDIHIHIPEGAVPKDGPSAGITMAAAMMSAVTNRLVSAKTAMTGEVTL
                     RGRVLPIGGLKEKLLAARMAHIEKVLVPAKNRPDVEELSREITKGMEIVFVTSMEEVL
                     REALLGTAEKK"
     assembly_gap    15044..15053
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<15054..15222)
                     /locus_tag="ACZPCR_09620"
     CDS             complement(<15054..15222)
                     /locus_tag="ACZPCR_09620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009262989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LON peptidase substrate-binding
                     domain-containing protein"
                     /protein_id="HIR1231169.1"
                     /translation="MERTQLTIPVVALRGLTVLPQMIISFDISRKKSIAAVEKAMVGD
                     QKILLVTQKRTE"
     gene            complement(15318..16622)
                     /gene="clpX"
                     /locus_tag="ACZPCR_09625"
     CDS             complement(15318..16622)
                     /gene="clpX"
                     /locus_tag="ACZPCR_09625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HIR1231170.1"
                     /translation="MPGRQDDNIRCSFCGKTQDQVRKMIAGSNGVYICDDCIELCAEI
                     LEEELGDAENTKGIDFSGINLLKPKEIKEFLDEYVVGQEAAKKVLSVAVYNHYKRITS
                     QGAQEVDLQKSNILMLGPTGSGKTYLANTLAKILNVPFAVADATTLTEAGYVGEDVEN
                     ILLKIIQAADYDISKAEYGIIYIDEIDKITKKSENVSITRDVSGEGVQQALLKILEGT
                     VASVPPQGGRKHPQQELLQIDTTNILFICGGAFDGLEKIVENRLGAGSIGFEVEIADR
                     QSSDIDELLAQVMPEDLTKFGLIPEFIGRVPVTVPLKSLNEDALVEILSRPKNAIVKQ
                     YQALLDLDGVKLEFTDDALYAIAHMAVERKTGARGLRAIMESVMMDIMYEIPSDSSIG
                     ICTITKDVVEGKCGPEIVYRENTVPRKSFTGRLKKDKTGEIA"
     gene            complement(16652..17233)
                     /gene="clpP"
                     /locus_tag="ACZPCR_09630"
     CDS             complement(16652..17233)
                     /gene="clpP"
                     /locus_tag="ACZPCR_09630"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012198407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HIR1231171.1"
                     /translation="MSLVPYVIESTSRGERSYDIFSRLLKERIVFLGEEVTDVSASLI
                     VAQLLFLESEDPNKDIHLYINSPGGSVTAGMAIYDTMNYIKCDVSTICVGMAASMGAF
                     LLAGGAKGKRLALPNAEVMIHQPSGGARGQATEIQIVAENILRTKKKLNEILAANTGQ
                     PYEVIERDTDRDNYMTAEEALKYGLIDRVITGR"
BASE COUNT         3922 a         5047 c         3963 g         4303 t
ORIGIN      
        1 gaatttcctt gtctttctga ttctctgtat tctcattttc cttgttgtga atttcctgtc
       61 ctataccaag gattttcttc agactctggg ttccgggcgg ggcgtccaga tggtgaagga
      121 tgaggaaacg ggacagtttg ttttccgcag aaacagcgga aaaagaagcg gcgtcagcct
      181 tggaaggcct ttaaaatacg gctttatcgc tatcggcctg atcattattc tcatgactgt
      241 cgcttctctt ctgggactcc agtttttcaa cgccacccgt taccgggatc tgattaccat
      301 tgaggatggc gattttgccc aggacgtagc tgagcttaac atgtcccaga ttcctgtagt
      361 tgacaaggat actgcctccc gtctcggcag ccgtaagctg ggagagatga cagagctggt
      421 ttcccagttt gagattcagg acgactacac tcagatcaac tacaagggtt ctccctaccg
      481 cgtgacgccg ctccgctatg cggatccgat caagtggctc tttaaccaca aggaaggcct
      541 tcccgcctac ttaactgtgg acatggtaac tcaggaaact aacctggtat ggctggaaaa
      601 tggaatgaga tactccccca gtgaatattt cttccgcaac atttaccgct atatccgttt
      661 taaatatccg acgaagatgt ttgaaactgt atcttttgag atcgacgaca acggaacgcc
      721 ttactggatt gctcccacta tctcctaccg gattggctgg tgggacggaa aagacatcga
      781 cggcgccgtg ttagtcaatg ccgttaccgg cgaaagtgaa tggtacgcca aggaggacgt
      841 tccccagtgg gtggatcagc tctactacgc ggagcttctc atcggccagc tggacgacaa
      901 tggaagattc cagcacggat atattaactc tgtcttcggc cagaaggacg tgcgccgtac
      961 tacctacggc tacaactata tggccatcaa cgacgacgtc tatctgtaca cgggcatgag
     1021 ctctgtgaca gccgacgagt ccaatatcgg ctttgttctt gtcaactgcc ggacgaagga
     1081 aacgaaattc tacacggttc caggcgcgac ggagacctct gccatggctt ctgcccaggg
     1141 acaggtgcag cacttaaact actctgctac cttccctctg ctcttaaata tttccaaccg
     1201 tccgacgtat ttcctctctc tgaaggacaa tgcgggactt gtgaaaatgt acgcctttgt
     1261 agacgtggag cagtaccaga tcgtaggaac cggacagact attgacgagg ccaagagcaa
     1321 ttacagaaaa gcgctgaacc tagaagacgt ggaggtgcag gagcttgtgg acagcacgga
     1381 aatctccgga accgtcgctt cccttgccag cgcggttgtg tccggcaata cctgctatta
     1441 ctttactctt gagggagatt cccaggtata caccgcctct gtagacattc acgagaagct
     1501 tcctttcatg cagccaggcg cagaattatc cttctcctat gcggaggacg gcgctgtccg
     1561 gcgggtaaca gaggttcacg agcttgccct tcctgacagt ggggacattt ccagccagac
     1621 ggaagctccc gaagcagatt ccatccagcc tgagacttca gaagaagtct ctccggctga
     1681 ttctgaggcc ggacagccgg cagacggaca gtaggaggaa gctttcccat gaaatctgac
     1741 gatattatta tgaaaacagg aattgtacat atcctggact cgtctgtggg cgtgccggtt
     1801 ctctccgact gccccatcga cctgtccggc gatctgtccg agtttctgaa ggcccacatt
     1861 gaaaaattga cggagagcga cgacgtcaag ctctgccgct ttggaaacga ttctcctgtc
     1921 aagcagcttc tggagcagtg taccccggaa acctttgtgg agaccagcaa gcagctggcc
     1981 cagctgctct acgacattat gaacgctaat attgatattc ctccggccga cgttgcggtg
     2041 gtggtcttct cctccggagg aagcgattat ctggcccttc tgaaaatgaa ttacaagact
     2101 tcctacaccc atctgaccaa ggagcaggaa ggcaaaaatg ccaacagcat tattctgcag
     2161 aaggctctgc ttccaggcca ggggcagaag ctctccgagg cctttgtcgt gaatctggga
     2221 acgggagagc ttctggtgac ggagaaaaag tacgaggtaa acggcgaaaa acgcctgtat
     2281 ttttccgagc tgtatctgga atgccacgct cctctgtctc agaaatcaaa gctggatatt
     2341 gtgacaagag cggtggagca ggtcaaccgg aagtattacg gggatgacga cgcagaacgc
     2401 aaaatggaaa ttaaaaatgt catttacaag gagctggagg aggagggcgc catcaaggtg
     2461 gaatctctcc gtgaaaaggt ttttccagac agcccggaaa tgcagactgc ctttgatgag
     2521 aaaatggaga aatacaatct gtcctacgag acagtccagc ccaaaaatga gcagacggta
     2581 aaaaaattcc agagccagcg tctgacgacc gatacgggaa tcgagatcac tattcccatg
     2641 gaggagtacc agaatccaga ccgggtggaa tttatcacaa atccagacgg aaccatttcc
     2701 gttctcatta aaaacatcgg tcatctgatg tcaaagtagg agaaacgcct gacggaattt
     2761 ttcctgctga atccattgaa tgcagaaaga gaggaggaag gtttcattcc ggcagtttta
     2821 tgccgaagcg aagccttcct cctctctttt catcttcctg ttatgttcca cctgctctga
     2881 tgctatatca tggctctgta gcctgccttc cacctggaca gaagctctcc ctctgcctgc
     2941 ctgcgggcag tcttttcctg gttaaacagc tcctccgcct gtctcacgct ctcagaatgt
     3001 ctggcccggc ttaccgcctc ttcaaattct tccttccact gctctttccg gctgtccagc
     3061 agtccggcgc cgaatctggc cttgacagac agctttggat ttagaagcgt cagatggtac
     3121 atccgcttta ctgtgtccgg atcctttctg tagctccagg acatctcata agcctgcatg
     3181 gccttgtcaa accagaacag gcctgcatag caggcagcca tattgttcca gacctttccc
     3241 agaaattcgt catccgccgc cttgttgtgc tggctgtcca gcagcttttc atatccccga
     3301 agcgctgtgc cgtactggcg cagcgtgtaa tagtagtctg ccgtagcctt ggcaaactcc
     3361 agcgatccca tattccgata ggagctgatc ttctgccgga aagccgtaat ctctttcgga
     3421 ctgtaaaaat ggcattcttc caggaacata aagatcagct cgtcctcgtc cgcgccggtt
     3481 ctcagcccgt tttccagcct tgccgccaga acagtcattc tcagctcttt ctcaataaac
     3541 tctgtcagcc gctcatccag aaaatgatcc atggccagca gagggtaatt ataaatcaca
     3601 tagcagagct cctgggaaga ccagatatgg acgcccaggg cctcaatata gagaggatgc
     3661 gttacctcct cctgtctgca cagtatgaaa ctcatagtac cacctcttgt ctcaccatgg
     3721 cctttgaagc tggaaacagc tcgccaaagc ctttatccct taccataata atcatggtgc
     3781 tctcatctga aaaaccgatg gtcacctgaa tccggttcgt cttgttttca cggatgggga
     3841 aatcctgaag cgccacaggc accactctcc ttttcctctg atccagggag gaaatcacaa
     3901 actccagatg gtcttctcca tccgcaatca gatccaccgt gcttctggcc tcataccagt
     3961 tgtctcctgc tgccgccaga accaggctgg tatccttccc ccggttcaaa acctgcaggg
     4021 aaatggtata ctgaagcctt ccctcacaga tacaggtaaa cggataatcg gtgcgttctc
     4081 tctcataatc tgcgccccgg taggcggctc cctttgaaaa caggccgtac tctgcaaaca
     4141 ctcttctctt gctgcagatt ttcttcataa agctgtgggc ccagtctgtg gtggcaaagc
     4201 cgtctcctgt aagaataacc gcggaaaaca gacgcttatc taaaattctg tctgcacagg
     4261 ccgccagaaa ctgatcctct gaggccgctc cctccggtct ctttaaatac tccaatgtaa
     4321 tttcttcctg aagatcctcc cggtcggcag tgacaatcat tcctctggat cccctctgag
     4381 tcttcagctc atagtacctg gcacagccct cggacagctc gaacatcccc acctgattgc
     4441 tccacacatc cctcttctgg ctcatcacat agtagacaaa gctctccgta tggctcacga
     4501 tgtgaacgcg gcttctgtca attcccagat aatcggcgca gtaaagaagg ctgtccatca
     4561 gccttatctc cggctttctc agggcaatga ccagacggct tatctcctcc ttctcagcct
     4621 cctttttcgg aagctccagc gcctccttta aaaaacgctt cagcaaatcc agtcctgtat
     4681 aaccgttttc cctctccggc tccttctcgt cccgctgtat tctggagaga agactgtccc
     4741 agtgcggatc gcctgccatg gcgcgggcag aggcttcctc ccccacatac cactcctctg
     4801 attgtctgtt tttgcagacc gctgtcttga tcgtccatgt ccgttccggc tccagcgccg
     4861 ttatggacgt ataggtatcg cacaggtcga ctcccagtac aagtccgtcc atctctcagc
     4921 aagccccttt cttctattac ttgatcctgt ccattttccc tgtctgccct tccccgtctg
     4981 cttctgcctc tctgttaggt tagagaagtc cgaacagcgc ctgggaaaca gcgtcagccg
     5041 tcaggtactc ctccatctgg cttctcaggg tattttcatt tttcatgtca aagctcagtc
     5101 ccatctggtt gagaagcgca aagcgcgttc cctcctgctt taccggcggc tctctgcgct
     5161 ccaggcttcc ggaaacggca ggggcctgat ccccccgttt tctgtaaatc tggtactcca
     5221 ggacctctcc ctcaaaaacc accttttccc gcacgaaaat gcccttgtaa acctccttca
     5281 tctcctcgca gacaaactcc tgctcctctg gaagcacgcg caccatcagc acaggatccg
     5341 aatccttttc cccgtggaat tcgatcatct ctttgtcgag aagccgttcc ggcacagccg
     5401 caaacctgga taattcttta aaataggcaa attccatgcc agcctccaac agcacctctg
     5461 taaccgctct gcacagctcc tcctgctcct tcgtgagaga cggcagagaa gcgtaatacc
     5521 tggtcagggc cagcaggtaa atatccggga tccggtcccg gtcggagctg ttgtagaccg
     5581 ctccctccag gtaggcgaac actttatcct gagccggttt ttcctccata aaatactcga
     5641 tgcactttac ggtaaaatag gcctttacaa tcatttccct ggtctttttc ctggatgcgt
     5701 acaggtcaaa cacccggtct atcttttctg tgcagccggt aaacagcatc tggcagagca
     5761 gccgctcttc catatctgcg gtatccgcct gatctctgac agccgccagc agaatgcaga
     5821 acatctgatc caccgttccg ttaaagtatt cgcacagata gctgagaata gcgccgtccg
     5881 ctctgccctc ctggaaaatc tggaaagaaa gatttaacag gcgctcatcc tcccgcatca
     5941 ggctctctaa cagcattttt acaaccagct ttttcagttc agccgtctcc agccgttcgc
     6001 ttccatatcg gcacagcata tcgtatgcct ctgaatagca gccctgggca atcagcgctt
     6061 tcataatctg cgctctctca tcggggctta tggaatcctt gtcagcagcc agcaggaagg
     6121 cagctgccct ctctctgtct ccctgtccgc ccagggccag actgtccaca tagcgtcgga
     6181 tcagggcaga cataatcttt ttcctgtaaa tcgggtgaag cgacggctct gaaagggctt
     6241 tcacaaggat ttcctcctcg ttttccgtca tggatccaac cgctcccgct ctctccttct
     6301 cctcccggtc aagagccctc tggcaggcat ttaacagcag gctcgtgtgc tccggataca
     6361 cctgaaagca ccgcttagcc agctcttcct cttccatcgc cgcagacgtc tcgtaaggcg
     6421 tgctcataaa ccggtttccg gcctcgtcct ggaacatcag aatatcgcgg ctggaaaaaa
     6481 gaggcacata agcggtctgc tctgtcagag ggtaggcatc ctctgtcgtc agctcctcat
     6541 ggcgcagtat gacatatcgg atacggctgt ccttcaccgt aatgcagttg gatttcagca
     6601 cagacggaag caccctggcc agctgccgat ccaccacatc cgggtaaatc accgttttgt
     6661 aaatcaccgc cagatctctg ctgatctttc ccgcaaacag ctgggaaaga gcgaattttt
     6721 caatttccct ctcataaaac cggaacatcg actcgtcatc ccggtaaaat tccagcacat
     6781 tccggtacag tctggccttt cccttctcat tcagttcatt tccataagaa aaatagagaa
     6841 gcatttccct ggaaagaggc ttttcgtaat tttccggaag gcagtacaga taatactcgt
     6901 aaagctttgt cagagccagc tttgcctcta cgcccttttc gtaccatgaa aaatacttct
     6961 gttcccggca tcccccgcgg atcagcatgg cgcagacagc agaaaggatc tccgtattct
     7021 caaactgagc ataaagagct gtcagtattt taagcccaaa gggccaaaat tcctttttcc
     7081 tgtcaatcac atctgccgcg gccagagccg tttcctcaga cagcagtcct cttctggctc
     7141 caaagtagat cacatgggac tcaaagggct ccatattcct cagaaactcc ggttctctcg
     7201 ccagaattct gcaggcttcc agaaacagga acgggctggc ggctccctct ctgaattgtc
     7261 tgcgcagatc tgcatagacg gcggccgggc tggcggccag ctccggatcc agacggagaa
     7321 tcatcatata taaatagaag tttcccggtt ctgccgccag atggcggcgc agcagcctca
     7381 ggagagcgtc tctctgcgcc tcgtcgcctg acagggaaac ctggatatac tggaacagca
     7441 gatagttcat aaccctgcta tcccgctccg cgaggatctg ttccctgaca gaatccagga
     7501 tggcctgggc ccggtctctg cgccccacag ccaaaaggtg ctccgcctcc agcaggcgga
     7561 ccgcgctgtc ttcataggaa attttcatct gggacagcag acgtcccata gaagaagcca
     7621 gacgcctctg gctaagcgtt ctctcatcct taacctcagg ctttttcttc ttcctgcctg
     7681 tctgcctggt ctggttctcc tcctgatcct cttctccctc gccgccggac tcgtaagacg
     7741 gctctgcgag agcctcgtac tgcagccgca gctccatata atttctcaga ttctcccgga
     7801 aggaaatgct tttctgggcc ttctctcctc ccactgtcac agaaatggaa atcttgtgcg
     7861 tctccccggc ggccgtcaca aagacagcgc cgtaattcct tcccccgtga aggttttctg
     7921 acaaaatctg aaacggaaga gagcatgctc cgtttttaaa atcctcctga gtcacggttc
     7981 gctttaacag gtggataaaa tctccgtctg cctctgcttc caggcagata tatccccacc
     8041 ctctgctctt aatctcgatg gaatcctgaa tatggccgga cggattctcg taggttttct
     8101 gctcttcatc gaaaaaaata cagaagggct cctttactcc gagcccattc agaaattctt
     8161 ccagaaagca ctgcctgctg ccgtgtccct tcagcccctc gtataccgcc cgcacatggg
     8221 gatcctgcat aaagggcgct tctgcaaaat caggataatc taacagcctg agagccgtat
     8281 ctccgtctct ccccgccagt ctggcaaaat cctccggcgt cttaaggctg ctcagcacgc
     8341 ttcccgacgc agccagatcc acataaaaca catagggaat ttctatctct ccgcagctgg
     8401 tgaccagatt gaacattccg tcaatctcat caccagcctc cataaaggaa gtgtccacct
     8461 cataagcgat ccggttcctc actccgccaa aggacgcgtg atccgcaaag atccggactc
     8521 tgtcgctggt ggaatacgcc agtcccttga cgcttcctcc gccctcggtt ccgataaata
     8581 gttctcttct taccgttgta tttgttctga ttgtctcttc tatcgcatcc ggcgtccaga
     8641 tcacctttgg ttttgatgta tccacaatgc ccatggccag ccggttgatt cgttctctca
     8701 tagcattctc acctgcagta ttcgtattgc ttccaaaatc tgttttctat tttagcatac
     8761 tttcctttca attacactac ataaaatcga ctttttggca aaggcttgat ttcagaaaat
     8821 aaacttgata tgatagatat tatcaggaat aaaatctcag aaaagaaagg gatcgcatta
     8881 tgacaaacag tgaaaaagct ctgaaactcc atgaagagtg gaatggaaaa attgagaccg
     8941 tctccaaggc agccgttaaa agccgcgagg atttagctct ggcctacacg cccggcgtgg
     9001 cggagccatg caaggtgatc gccgagaatc cggaggcagc ctacacatac acgatcaaat
     9061 ccaacaccgt agccgtggta tccgacggaa gcgccgttct gggcctggga aatatcggac
     9121 cgctggcagc catgccggtt atggaaggca aagccgtcct cttcaaggag ttcggcggga
     9181 tcaacgcctt ccccatctgc ctggacaccc aggacacaga ggaaattatt gagaccgttg
     9241 tccgcattgc tcctgctttc ggcggcatca acctggagga tatctccgct ccccggtgct
     9301 ttgaaattga ggagcgctta aaagagcgcc tctccatccc tgttttccac gatgatcagc
     9361 acggcactgc aatcgtagtg ctggccggca ttatcaacgc cttaaaggta acgggaaaga
     9421 agaaggagac agcccaggtc gttgtaaacg gcgcgggcag cgcgggaatc gccatcacaa
     9481 agctgctcct tacatacggt tttcagaata tcaccctctg cgacaaggcg ggcatgatct
     9541 gcgagggcat ggagggtctc aactggatgc aggaaaagat ggccaaagtg accaatctcg
     9601 gaaagcggac cggaagcctg gcagacgcct taaagagcgc ggatatcttt gtgggagtct
     9661 ccgctccagg catcgtgacg cctgagatgg tcgcttccat gaaccatgac gcgattctct
     9721 tcgccatggc caatccggtt cctgagatca tgccggatct ggccagagag gcaggagcca
     9781 gagtcgttgg aaccggacgt tctgacttcc ccaaccaggt taataacgtc ctgatcttcc
     9841 ctggcatttt ccggggcgct ttagagggac gggcctgcgc catcacagag gagatgaaat
     9901 tagcggcggc cgaggccatc gcttccctgg tatctgagga ggaattaagc gacgtcaata
     9961 ttcttccggc tgcctttgat ccgagagtgg ccgacgcggt cagccaggct gttaaggagc
    10021 atatccgtta gcctgcccca atcagttttt ctttaaagga gttttgctat gttagctgaa
    10081 ccaatgacat tatacaagct gatgaatctg tacatgctga aacaggtaaa ttttcctctg
    10141 acaaacgccc agctttccag cttcttcctg gatcgggact atacaagcta ctttacgctt
    10201 cagcaggcct taaacgacct gctggacgcg ggactcatcc gccaggagac ggttcacaac
    10261 agcacccgct acgagattac cccggagggg gaggatacgc tggatttctt tggaaaaacc
    10321 atttcccccg ctattgtgga ggacatgaac gagtacctga aggagaacaa attccggatg
    10381 cgggacgagg ccggttttat ctctgatttc tataaatcca ccaatcagga ttacaccgtt
    10441 cactgtgagg tgcgggaggg gaaaaacgtc ctgatcagcc ttgacgtctc cgtgcctgac
    10501 aaggaacagg cggagagcat gtgcaatcac tggaaaggca aaagccagga gatttactcc
    10561 tttattatga aatctctgat gagcgacaag ccggtcaagc cttaacagga gaccggtaca
    10621 ggaggaatcc catgtttcga acacggacaa agccggagcc tgtacgcctc cgcgatctca
    10681 tccggggcga tttcagtcag gccagaaggc ggtatcagat gtttaagcgg aagtgtttca
    10741 tcttcctctt ccttccggca gctgttttcg ccatcctgaa ccgggcagcg gaggaatatg
    10801 cgaaaataaa ggccctgcag gaaaaaaatg cgcgccgtcc atagcgcgcg tctctcacta
    10861 aaagaaaaga acagccattc cggccgcttt ttaaggcagc ctggacagct gttctttttt
    10921 tgaagccagc gtcagtgtac actgacgcta ttttttatgt ttccctccgc gcaccgacgc
    10981 cagcatcttt tcatgcagaa cagccatcag cgccaggata acaatcagaa aaacgggaaa
    11041 taaagccgcg cctgcatggc tggcaatcac gccgaacaga ggcggcatgc tgagacttcc
    11101 cacataggcg aaggccatct gcactccgat taccgcctgg gatttatccg ccccaaaatg
    11161 ctctggcgta gagtgaataa tggatggata aacaggagcg cagcccagtc cggtgagaat
    11221 caggcccgct gacgcagctc tgctcccaaa gggcaggaaa aggcagagaa ttcccagaaa
    11281 aatcacagct tcgccaaggc gtatcatccg ggtatccccc agcttcatag tcagaaagcc
    11341 gctgatcgct cttcccgccg taattccaag gaaaaacagg ctgacaaaac cggccgccgc
    11401 ctctgctgaa attcccctgc ataacaccag atagctgcca gcccaaagtc ccgccgtctg
    11461 ctccagagcg ctgtagcaga aaaaggccgc cagaatttct tttgcacctg ggagcctgac
    11521 aatcccgcca atggacaggg gcctgcggcc tgcctctgtg gacaggcagg ccgctttctc
    11581 tccggatgcc cgcctctttt tccacagggg aaggctggct gcaagaacag cgctaagagc
    11641 aaactggagc acggcaatac agcggtatcc catattccat ccatggccgc cttccagcgc
    11701 agcccccata atatacggtc ccagggaagc tcctacgccc cacatgcagt gcagccagct
    11761 catatggctt cccgtatagt aaagcgccac ataattattc aaggaagcgt ccacgctccc
    11821 ggcgccgagg ccgtagggaa ccgcccacag gcacagctcc agataggagc cgctggtgga
    11881 aaatcccagc agggacacag ctgtcatgca tacgctggca gcagtcactc ttcctgtgcc
    11941 gaactgcctg gtcagacggt cgctctgcag actggaaaaa atggtgcccg ccgagataat
    12001 catggaaata acgcccgcat aggacacggg aactgaaaat tcccggtaca tgacgggcca
    12061 ggccgatccc aggagggaat cgggaaggcc gaggctaata aaggccagat agatgattcc
    12121 aagcagcaaa tgaaacacta ctgctcttcc tccgcagcag ttttctcaat atagtcccag
    12181 atctcttccc ttccctgctt cgtctcggca gaaaacggaa tcagaacgtc ctccggctgc
    12241 atggacagtc cctcccgcac cattttcaca tgtttggcta tctggcttct ctttaattta
    12301 tccgccttgg tggcaatgat caccgggcga tagccctggt ctaaaatcca ctgatacatg
    12361 aggcggtcgt tctccgacgg atcgtggcgg atatcaatca gcagaaatac gcattttaac
    12421 atcggagact tgtgaagata gttctcaatc atctttcccc atttggcctt tacctcctgg
    12481 ttggccctgg catagccgta gcccggcagg tccacatagt agaaggcgtc gttaatgtgg
    12541 taaaaattga tcgtctgggt ttttcccggc tgagccgacg ttctggcata ggccttccgg
    12601 ttcatcagcg cgttaatcag ggacgatttc cctacgttgg acttcccggc aaaggcaaac
    12661 tccggctgcg tattggccgg aagcttgctg gtgatgccgc agacagtctc caaatctact
    12721 ttttttataa tcattttcgt ttccttttct ctcttactct gagaagagca tccatttttc
    12781 ctgtcttatt ttttctcagc ggttccaagc agagcttccc ttaagacctc ctccatggac
    12841 gtcacaaaga caatttccat gccctttgtg atttctctgg acaactcctc cacgtccggc
    12901 ctgtttttcg ccggcactaa aaccttctct atgtgagcca ttctggccgc caaaagcttc
    12961 tccttcaagc ctccgatggg aagaacccgt ccccgcagcg tcacctctcc tgtcatggcc
    13021 gtcttagctg aaaccagacg gtttgtcaca gctgacatca tggcagctgc catggtaatt
    13081 ccggcggaag gtccatcctt tggcacagcc ccctccggga tatgaatgtg gatatcatgc
    13141 ttctcaaaat agctgttttt cacgccatat tgatctgccg cagagcggac atagcttaaa
    13201 gccgtctggg ccgactcctt catcacatct cccatctgtc ctgtcagctg gaggactccc
    13261 tttccaggca tgacgtttac ctcgatctcc agagtatcgc cgcctacgct ggtccaggcc
    13321 agtccccgga caattcccac ctgatccgtc tcacatgcgt cctcgaactg gattttctcc
    13381 cgtcccaggt atttttccag atttttctcc gtaacccgga ttgtcttctc atgtccggct
    13441 ttttcttttc cagctttctt atcagccttc tctgtcttaa tctccgctgc cttgagagac
    13501 tttgttttct gccggctctt ctctctcatc tgctcctcca gaatctctct ggccgccttt
    13561 ctgcagatat ctccaatccg tctctccagg tttctgacgc ctgcttccct ggtgtaattg
    13621 tggataatct tttccagagc tgctcccgaa acggacaaat ccttcttcgt caggccgtgg
    13681 cgctccatct gcttgggaat gagataattc tttccaatgt ggaatttctc attctctgtg
    13741 tagctgctga cctctatcac ttccatacgg tccaacagcg gccctggaat cgtctgggtg
    13801 gtgttggcag tggcgataaa aagagcctcc gacagatcca ccggaatctc cacatagtga
    13861 tcccggaatt tcacgttctg ctcgctgtcc agaacctcca gcagagcaga ggaggtgtct
    13921 cccttgtagt cgctgctgac cttgtcaatc tcgtctaaca gcatcagggg atttttcact
    13981 cccgcctgct tcagaccctc cacaatgcgg cctggcatgg cccccacata agtcttcctg
    14041 tgtcctctga tctccgcctc gtcgtgaacg cctcccaggc tgatgcgcac gtattttttc
    14101 cccagcgctc tggccacaga tctggcgatg gacgtctttc ccgtaccagg cgggcctacc
    14161 aggcagataa tcgggctggt tccctttttc gtcagaattc tgactgccag gtactctaac
    14221 acccgctcct ttaccttctc gaggccatag tgatcctcgt tcagaatctc ctccgcatgg
    14281 cgcaggtcgt tattatcccg ggtcacctta tcccagggaa gctccagcac agtttccagg
    14341 taggttctga gcacgttggc atcctggctt ccgcccggca tccccttaaa ccgctcgatc
    14401 tccttggcaa ttctgtcctt tacctctttt cccgccttga gggaagccag cttttccttc
    14461 agctcatcag cgtcggacat ggggttatcc tcccccagct cctccctgat aatccgcatc
    14521 tgctctcgca gaatgtaatc cttctgattt ttgtcaatgg cagcctttac cttggactga
    14581 aattcctttt tgacctgaaa tacttcgatc tctgtcagca gaatactcac aatctgctca
    14641 tactgcccgg tcagatatac ctgatccaga acctgctgct ttaccgtata ttcccacggg
    14701 aactgaacgg cagtctgatt taacagctca ggaagctccg taatcgccag caggttcggc
    14761 agaatctccc tggctgccgt ctgatccacc cggccgtatt cctccagctt ctccttcaca
    14821 atccggatca tggcctcttt ctcaacctgc cccagatttt cttcctccgt cgctcggatc
    14881 tccgcctcgc cttccaggta ggagccgtcg gcattcagag ataaaagctc tgctctctcc
    14941 tctccctcgg ccatgacgcg gatcactccg cccggcagct tcaccagctg ctttaccatg
    15001 gcaatggttc ccatctgata cagatcctca gcctgcggat tcannnnnnn nnncctccgt
    15061 ccgcttctgg gttaccagga gaatcttctg atcccccacc atggcctttt ctaccgctgc
    15121 aatggatttc tttctgctta tgtcaaaact aataatcatc tgcggcagca ccgtcagtcc
    15181 gcggagagcc accacaggta tagtcagttg tgtacgttcc atttacttct cctgattttg
    15241 taaatctctg ttctttgcaa aaggggatct gtagctttta cagatcccct ttttaacaac
    15301 actgcgattc ctgccgatta ggcaatctcg cctgtcttat ccttctttaa gcgcccggta
    15361 aatgacttac ggggtactgt attttctctg tatacaatct ccggcccgca tttgccctcc
    15421 accacatctt tggtgatcgt gcagatgccg atactgctgt ccgacggaat ctcatacatg
    15481 atatccatca taactgattc catgatagcg cgcagtcctc tggctcctgt ctttctctct
    15541 accgccatat gggcaatcgc gtacagggcg tcgtctgtaa actccagctt cacgccgtcc
    15601 agatcgagaa gcgcctggta ctgttttaca atggcattct tcggcctgga cagaatctcc
    15661 accaacgcgt cctcgttcag agactttaac ggcaccgtca ccggaacacg tccgataaac
    15721 tcaggaatca ggccgaattt cgtcagatcc tccggcatca cctgggctaa cagctcgtca
    15781 atgtcagagc tctgcctgtc ggcaatctcc acctcaaagc cgatggatcc ggctcccaga
    15841 cgattctcta caatcttctc caatccgtcg aaggctcctc cgcagataaa gagaatgttg
    15901 gtagtatcga tctgaagaag ctcctgctgc ggatgctttc tgcctccctg aggcggaacg
    15961 ctggcaacgg ttccctccag aatctttaag agggcctgct gaacgccctc gccggaaacg
    16021 tctcttgtga tggatacgtt ctctgacttc tttgtgatct tatcaatctc gtcaatatag
    16081 ataattccgt actcagcctt gctgatatcg taatcagctg cctggataat cttaagcaga
    16141 atgttctcca catcctcgcc cacatatccg gcctctgtca gtgtcgtggc gtcggcgact
    16201 gcgaacggca cgttcaggat tttagccagc gtgttggcca gataggtctt gccggatccg
    16261 gtcgggccca gcatcagaat attgctcttc tgaagatcca cctcctgagc gccctgggag
    16321 gtaattctct tataatggtt atagacagcc acggaaagca ccttcttggc tgcctcctgt
    16381 cctaccacgt attcgtcgag aaactcctta atttccttcg gcttcagcag attgatgccg
    16441 ctgaaatcaa tgcccttcgt attctctgcg tcgcccagct cctcctccag aatctccgcg
    16501 cacagctcaa tacagtcgtc acagatatat acgccgttgg aaccggcgat catctttcgt
    16561 acctgatcct gcgttttccc gcagaaggaa catctgatat tgtcgtcttg tctgcctggc
    16621 attcgcccac ctctactctc tctcttcata atcagcggcc tgtgatgaca cggtcaatga
    16681 gaccatactt cagcgcctct tctgctgtca tatagttgtc gcggtccgta tctctctcaa
    16741 tcacctcgta cggctggcct gtattggctg ccagaatctc gtttaacttc ttcttcgtcc
    16801 tgagaatatt ctcagcaacg atctgaatct ctgtcgcctg gcctctggcg ccgccggaag
    16861 gctgatgaat cataacctcc gcgtttggaa gagccagtct cttgcccttg gcgcctcccg
    16921 ctaacagaaa ggctcccatg ctggccgcca ttccgacaca gatagtggaa acatcacatt
    16981 taatgtagtt catcgtatcg taaatcgcca ttcctgctgt tacggaaccg cccgggctgt
    17041 tgatgtagag atggatatcc ttgttcggat cctcagactc cagaaacagg agctgcgcta
    17101 caatcagact ggcggacaca tccgttacct cctcgcccag gaacacgatg cgctccttta
    17161 agagcctgga gaaaatgtca taggaacgct ctccccggct ggtggactca atgacataag
    17221 gtactaaact catacaatgc ctcct
//
LOCUS       DBMDUW010000054        17239 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_1923_length_17239_cov_3.380091, whole genome shotgun sequence.
ACCESSION   DBMDUW010000054 DBMDUW010000000
VERSION     DBMDUW010000054.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 17239)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 17239)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17239
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1923_length_17239_cov_3.380091"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            610..1797
                     /locus_tag="ACZPCR_09635"
     CDS             610..1797
                     /locus_tag="ACZPCR_09635"
                     /inference="COORDINATES: protein motif:HMM:NF022641.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HIR1231172.1"
                     /translation="MKQECTARLPVSEEQILDIEIWLEQMALQGWFFTEPVGKWWYFS
                     KGEPARVRYRLDMITEKDGCLDEKKRECCEAEGWHFTASYKNLYHIFRAEDPSVPELH
                     INPQSAALVLKQYEKTARDSFIGKFTTLLLCAWLLFKEKGIWLSYPALTLADGSGLVF
                     LAAAAIVSAAAVRQLAIHRRIREICGRMRSGEAFIPTEDQVKNNRYRRWNIYLNFILI
                     VLFAVTLLQSCQNGGPVQQQLNDGEVFPALELIEDGTVQDSPENEGEMFYRSNLVLRQ
                     GYHMAQTAPVETAEHEMKLSSITADFYDARWSFFSEWLFSECRRQAEKEENAVYESLS
                     AEGFDTLLYGKTEKGQNVLAKRGTKILKLSYEGDTDLSKKWDLLRDIMDGKLEESFAP
                     SAD"
     gene            1950..2594
                     /locus_tag="ACZPCR_09640"
     CDS             1950..2594
                     /locus_tag="ACZPCR_09640"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231173.1"
                     /translation="MEETCSSCCTGLIQEGPEFNLHFADYGWCAYDSISEELVHRANL
                     VYEEQGIEAAERILIEYYQNEAPGQIDHILGAAPSFSMREGMIRQCFEDHREGRYYAS
                     VPLSLIIIDGAVNDYTKKKGFFTAATTVDPWDCLVGCTEGLTKIKLNFNQNRLKTNSD
                     PIYIPYRNGILHGRDINYGNEYVSCKCIALMFAIADWMIRRTAREEGLLPELEL"
     gene            2634..3500
                     /locus_tag="ACZPCR_09645"
     CDS             2634..3500
                     /locus_tag="ACZPCR_09645"
                     /EC_number="2.3.2.-"
                     /inference="COORDINATES: protein motif:HMM:NF015679.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0071972 - peptidoglycan L,D-transpeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0018104 - peptidoglycan-protein
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HIR1231174.1"
                     /translation="MRRKSDKLFLTAMAAAVMTLSSLGGTAASFAQAAQSQAGQPEKM
                     AAGPALESMENSKAKTEAVGETAEGRASQTSYEEYLPAQFDINTLKAAEETDHLILAV
                     GDGADQSSLTLWYYERGTDGRLSEVFGTRGTCGRAGITADKVEGDKKTPAGLYSFLMA
                     FGLKDDPGSQISYRKVQDGDCFVDDVGSRYYNQYVKGGEAQADWRSAEVLKNQGSCYN
                     YALVLDYNKDCVPGRGSAIFLHCPKVVNDTYTAGCIGIPEERMKTILTRAKADAKILI
                     VPDKDGLSEYIK"
     gene            complement(3537..4289)
                     /locus_tag="ACZPCR_09650"
     CDS             complement(3537..4289)
                     /locus_tag="ACZPCR_09650"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013213.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004536 - DNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HIR1231175.1"
                     /translation="MTALYDAHAHIGTTEELTLRKKQNILSLICATDPEEAKQLEELA
                     ADPSLSSVIRPAFGLHPWKADQISFRAMEPWLLKASVIGEIGLDNVWCSVPLSVQEKA
                     FCAQLELASAMKKPVVLHTKGQEKQIARLIRAYPNTYLVHWYSGGEGLSDFLDLDCYF
                     TIGPDVFYQPAVQKAAVLAPENRLLVETDGCSAVKWAYEQASFCKRPLPPWNDIKAVL
                     NHSIDTIASLRGISPEALVVKMEETFRRFCSV"
     gene            complement(4286..5032)
                     /locus_tag="ACZPCR_09655"
     CDS             complement(4286..5032)
                     /locus_tag="ACZPCR_09655"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1231176.1"
                     /translation="MKLEISDLSFSYEDKPVLDQLSLSVREGEFVSILGPSGCGKSTI
                     LKLLTGVLKKESGSLLANGREISHPAEHFAYMPQNDLLFPWKNILDNVCLYGRIHGFL
                     KEAREEALKHFPAFGLSGYEYKYPDALSGGMRQRAAFLRTALCHADILLLDEPFGALD
                     VITRGEMQDWLLSMRERLNRTVLLVTHDMDEAIYLSDRILILNGSPARITWETAISEK
                     NRTRSWLYSQGALRQTIYEKIVENHREEIH"
     gene            complement(5051..6139)
                     /locus_tag="ACZPCR_09660"
     CDS             complement(5051..6139)
                     /locus_tag="ACZPCR_09660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIR1231177.1"
                     /translation="MKKKHLKALCLAALAVLSLTACSGSKTSQSSAAASQAETEKAGA
                     DASLTESSQAASSKENLEDVTVILDYVANTNHTGMYAALDLGYYEEEGLNVKIVEPTE
                     GATATLVAVGKGDFGISYQEDVTIALTSEEPLPIKAVAALIQHNTSGFVTAADKNITS
                     PKDFEGKTYAGWGGPGEAAVLEAVMTQAGADFSKLNMVVSDGSGFAALENQADIMWFF
                     EGWDNITCEMNHFPINYMPVRELDDRLDYYTPVIIAGNDTLEQRPEMVKKFLKATEKG
                     YQYAISHPEESAEILHKYAPDYSLEMLTKSQEFLAGKYMEDTDVWGMMTDETWDNYTD
                     FMAEYGVIDRTIPASDCYTNEFLPGAGK"
     gene            complement(6186..6965)
                     /locus_tag="ACZPCR_09665"
     CDS             complement(6186..6965)
                     /locus_tag="ACZPCR_09665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004462115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1231178.1"
                     /translation="MSYAKRAAPVLALAAVLIFWETAVRLFQIPLYVLPSPTEVLNAL
                     ISDRLTLFSHSVITVAEALLGMGISLVLAVVLGILMDAFAPLRQVVYPILVVTQTVPM
                     IVLAPILIIYLGFGLAPKILTVVLMCFFPIAVSFTDGMAQLDPEYLHLARSFGASRWT
                     AYRLVKIPAAVPSLISGLKVAATYSVSGAVVGEWIGAQKGLGYYLLRVKNGYMLDKVF
                     ACVLVIIFLSLCMNLALWLANRIVSPSGHRQAQAGSRSSAS"
     regulatory      complement(7074..7178)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            7396..7770
                     /locus_tag="ACZPCR_09670"
     CDS             7396..7770
                     /locus_tag="ACZPCR_09670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013279782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin family protein"
                     /protein_id="HIR1231179.1"
                     /translation="MKFYVCQHCGNIVTFVKDAGVPVMCCGEKMSELIPGTSDGAHEK
                     HVPVVEAEGKKITVKVGEAEHPMLEAHWIQWIALETKKGSQIKYLNPGEKPEAQFILS
                     EDDEAVAAYEYCNLHGLWKKEI"
     gene            complement(7870..8148)
                     /locus_tag="ACZPCR_09675"
     CDS             complement(7870..8148)
                     /locus_tag="ACZPCR_09675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231180.1"
                     /translation="MNAAWKQDPRLKTMNQEKLNYLTKLAETVEQTPKDKLMPLFMSM
                     AAGSGQFQFTDSETDLLVSIMTAKMSPAEKKRVEMLRTLSKKLGGKKK"
     gene            complement(8168..8713)
                     /locus_tag="ACZPCR_09680"
     CDS             complement(8168..8713)
                     /locus_tag="ACZPCR_09680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231181.1"
                     /translation="MKTESDLKMTDLDYLTASPHLQMIKAALPYIHVPEQRFFSMIVK
                     LSELNRTMKLFEQKEDGMVGICSLEENASDSPLDMLNAMKPYGTSEEQEFIDLIVNFL
                     QGSRIYQSYRASAEDGPAGAAEAEKSSVCGDEEDGRGSSSRPLRGGPHFSIEHLKNML
                     PPEQQSKLETAQLLMQTMQGI"
     gene            8870..9013
                     /locus_tag="ACZPCR_09685"
     CDS             8870..9013
                     /locus_tag="ACZPCR_09685"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231182.1"
                     /translation="MGIRLIIEGNTAYEIDEDCLAARQEIWDSDSEEKPRENQEERRR
                     AKN"
     gene            9197..10003
                     /locus_tag="ACZPCR_09690"
     CDS             9197..10003
                     /locus_tag="ACZPCR_09690"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018597720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1990204 - oxidoreductase complex
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HIR1231183.1"
                     /translation="MIHYNHFIMAESLDEAYELNRKKSAVICGGFCWLRLQNRTVQTM
                     IDLSGLGLDQIEETEEGFEIGSMVSLRKLETHKSFQAWTRGAGADSLRHIVGTQFRNC
                     ATVGGSIYGRFGFSDVLTLFLALDAQVKLFKGGVLPLREFLDREEDGDILLSVLVKKG
                     QAFAAYESMRNEAVDFPVLTAAVCLRDGQFTVSVGARPGKARAYSVPETELSGEADQR
                     DEAVKALTEKFTYGTNMRASAEYRKYLAGVLVSRCLNRIEADRKEETSWN"
     gene            9994..10485
                     /locus_tag="ACZPCR_09695"
     CDS             9994..10485
                     /locus_tag="ACZPCR_09695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HIR1231184.1"
                     /translation="MELKCIINGCPVAADVAADLSLLQFLRAQGYKSVKCGCETTNCG
                     LCTVWLDSTPVLSCAVPAMRTQGRQVTTLEGLKEEAEEFGRFLGEQGAEQCGFCSPGF
                     IMNVLAMEREFDTIPSSDEIREYLSGNLCRCTGYAGQMRAIRNWLEYRKTKKGGDASC
                     RKQ"
     gene            10584..12839
                     /locus_tag="ACZPCR_09700"
     CDS             10584..12839
                     /locus_tag="ACZPCR_09700"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase family protein
                     molybdopterin-binding subunit"
                     /protein_id="HIR1231185.1"
                     /translation="MKKDAMALMTGRPVYTDDMAPSDCLIVKALRSPHAHALVKEIHT
                     EQAKKVPGVVCVLTWKDSPQLRFTQAGQTYPEPSPYDRYIIDRRVRFAGDVAAIVAAE
                     TEAAADKALKLIQVEYEVLTPVLDFRTAKDNPVLVHPEEDWKALCPVGADNKRNLCAS
                     GSEEEGDVEGTFARCDLVIERTYHTKANNQTMMETFRSYTFLDAFGRLNVVSSTQIPF
                     HIRRILANALGIEKSRVRVVKPRIGGGFGAKQTGVSEIYPALVTMKTGRPARMVYSRY
                     ESMIAASPRHEMEIRVKMGLSKEGMVRAVDVYTLSNTGAYGEHGPTTVGLSGHKSIPI
                     YTPEAFRFAYDVVYTNHQSSGAYRGYGATQGLFAVESALNEAADLLGIDPLAIRRMNF
                     LKEGQIMPAYYHELLESCHVEECMDRAARMMNWEEKFPRRDMGNGKVRGVGVGISMQG
                     SGISGVDVGTVSIRLADSGHYNMMIGATDMGTGCDTILAQIAADCLECDVDQIVVSGV
                     DTDNSPYDSGSYASSTTYITGMAAVQACGQLREKIVKKGSDMLGADPEQTDFDGAFVY
                     VLGEEERKVSLADISTRSMCGNNMTLEASASHSSPKSPPPFMCGMAEVEVDLATGQIE
                     VVNYKAAVDCGTVVNPPLARVQAEGGIVQGIGMTLYEDINYTEKGRLKENSFMQYKIP
                     SRLEIPDLQVEFESSYEPTGPFGAKSIGEVVINTPAPAIAQAVYHATGLWFRELPITP
                     EKIIRGLGKLK"
     gene            12836..13435
                     /locus_tag="ACZPCR_09705"
     CDS             12836..13435
                     /locus_tag="ACZPCR_09705"
                     /inference="COORDINATES: protein motif:HMM:NF024214.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HIR1231186.1"
                     /translation="MIFCILLASGLSRRFQGENKLFYQVEGLPMYRRVLSCACCVREE
                     LKAEQGWEVQIVLVTAYEEIAAEAGKASALAVRNREPEAGISHSVRLGVQAADPKPDD
                     WLLFSVCDQPWLRAEEVKAMITRTIRSGKGIGALSFQGEPGNPVLFRGDYRGELCALL
                     GDRGGKSVLRNHLEDVVLTEVSNAKALSDVDERPLDGGL"
     gene            complement(13485..13958)
                     /locus_tag="ACZPCR_09710"
     CDS             complement(13485..13958)
                     /locus_tag="ACZPCR_09710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003022573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HIR1231187.1"
                     /translation="MEIERKYLIEAAEMPENCLSYPFLQIEQAYLSVDPVVRIRRQDD
                     SFYLTYKSRGKMAREEYNLPLNAQSYAHLLAKADGLVLTKKRYLIPAKDAGIPASPLT
                     IELDVFEGAYQGLVLAEVEFSSKEEADRFVPPTWFGREVTFTGEYQNSVLAMKEI"
     gene            14337..15113
                     /locus_tag="ACZPCR_09715"
     CDS             14337..15113
                     /locus_tag="ACZPCR_09715"
                     /inference="COORDINATES: protein motif:HMM:NF017927.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HIR1231188.1"
                     /translation="MWSISEVKKRGWRQIGMYYWPAFLLLILFGIAARFENSMNIHME
                     RAVYWIVQEGLVHGLLHGGLLHGFELPDFGYMAESFFYGVLALSGLVGIGIKIFIVNP
                     MEVGCKRFFMESRELDRSAGIDRLLFAFISGSYLNVVKIMFLRDLFIALWTLLFVVPG
                     IVKSYEYAMIPYILSENPEADQREVFAATKEMMQGNKFQLFVFFFSFIGWLFLGILFF
                     GIGMLFINPYIRAAEAEVYSELRRHTGMYLNGFYEKQEEM"
     gene            15113..15667
                     /locus_tag="ACZPCR_09720"
     CDS             15113..15667
                     /locus_tag="ACZPCR_09720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1 family glyoxalase III"
                     /protein_id="HIR1231189.1"
                     /translation="MAEVYAFLADGLEEVECLAAVDVLIRGGVSVKLISISDRREVTG
                     SHGFRITADAVLDEVDLDGADAYFLPGGMPGTTQLRNCEKLCGALVKAAGEGKRLAAI
                     CAAPSVFGELGLLNGKKATCYPGFEEHLKGAVYTSQGVVTDGAVTTARGLGYALDLGI
                     ELLSLLTSRENGQAVKDAIQYDQH"
     gene            15830..17116
                     /gene="tig"
                     /locus_tag="ACZPCR_09725"
     CDS             15830..17116
                     /gene="tig"
                     /locus_tag="ACZPCR_09725"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002595547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HIR1231190.1"
                     /translation="MSLQVEKLEKNMAKLTIEVSAEEFEKAMKAAYNHNKGRFNIPGF
                     RRGKAPQAMIEKMYGAGIFYEDAANAVIDMSYPRELEACEEEIVSSPEIEVVQIEKGK
                     PFIYTATVAVKPEVTLGEYKGVEVEKTDAAVTDEDVENELKNVQDRNSRLVAVTDRPV
                     ADGDQTIIDFKGYVDGKPFAGGESQDYPLTIGSHSFIDTFEEQMIGMNIGETKELEVT
                     FPEEYHAKELAGKPAKFEVKVKEIKVKELPELNDEFAGEVSDFETLAEYKEDLKKTLT
                     ERKEKTAAAENENKVIDKVTDNAQMDIPEAMIKTRLRGMFDDYARRLQSQGLDINQYM
                     QFTGMTRENIMDQMKPQAVRQIKTGLVLEKVAEVENIQVEEAAVDEEIAKMAEAYKME
                     ADKLKGLLGERELEQMKKDLAVKKAVELLVAEAKLV"
BASE COUNT         4472 a         3832 c         4928 g         4007 t
ORIGIN      
        1 tttttaatga catataatat acttaacagg agagccggaa gggaactgct acttccccgc
       61 cccggcgatt aagttttaaa ctattgaaaa atagctcgtc gacttttgca gggtcaggac
      121 gggctatttt ttatgagtat aatttagaat tgcaacaatg agtaaggcaa cgcttacaat
      181 cagatttaat tcctcatatg tactcattgg caccacctcc gaacaggctc ggaacgggtg
      241 caactcgtcc cccggttccc cgggtaagta tattatctta tcatggtgca catgaagcag
      301 acgatgattg ctcggtcccc gttgtaactg ttggcgctca catcattcta tactgtttat
      361 ttaattttat cattaaattt agaaccacgt caattaaaaa agagaaccca aatgtcttaa
      421 aaaaatgtct gaaatttcct tgtacaatga cgctggaata gatttttgaa ttgagcgcag
      481 aaccaaggcg gaaggctggg aaaatcgtaa gaaaatcgac gcggttttgt gattggaaac
      541 cgcctctgtt tcctatataa tattagtaga cgctttaacg gaacgctgat tgtggagaga
      601 ggaggacaga tgaagcagga atgtacagcg agacttcccg tttcggagga gcagattctg
      661 gatatcgaga tctggctgga gcagatggct ttacagggat ggtttttcac agaacctgtt
      721 ggaaaatggt ggtacttttc caaaggagaa ccggcccgtg tcagatacag gctggacatg
      781 ataacagaga aggacggctg cctggacgag aagaaaaggg agtgctgtga ggcggaggga
      841 tggcatttta cagccagcta caaaaatctt taccatattt tcagggcgga ggatcccagt
      901 gttccggagc ttcatatcaa tccgcaatct gctgcccttg ttttaaagca atacgaaaaa
      961 acagcaagag attctttcat aggaaagttc accactctgc ttctttgcgc atggctgctt
     1021 tttaaagaaa agggaatatg gctttcttat ccagctttga ctctggcgga cggttcaggc
     1081 cttgtgtttc tggcggcagc ggcaatcgta tcagcggcag cagtccgcca gcttgccata
     1141 cataggcgga ttcgtgaaat atgcggcaga atgaggtcag gagaggcgtt tattcccaca
     1201 gaagatcagg taaaaaataa cagatacaga agatggaaca tctatctgaa ctttattttg
     1261 atcgtactgt ttgctgtcac gttacttcag tcctgccaaa acggcggccc agtccaacag
     1321 cagctgaacg atggagaagt atttcctgcg ttggaactta tagaggacgg aacggtgcag
     1381 gacagtccgg aaaacgaagg agagatgttc taccgttcta atcttgtgct gcgtcaggga
     1441 tatcatatgg cacagactgc gcctgtggag acggcggagc atgagatgaa actgtcttca
     1501 atcacagcgg atttctatga tgccagatgg agcttctttt cagaatggct gttttcagag
     1561 tgcagaaggc aggcggagaa ggaagagaac gctgtgtacg aatctttgag tgcggagggc
     1621 tttgatacac tcttgtatgg gaaaacagag aaggggcaaa acgttctggc aaagagaggg
     1681 acgaagattc tcaaactgtc ttacgaggga gatacggatc tgtcgaagaa atgggatctt
     1741 ctgagggata ttatggacgg aaagctggaa gagtcctttg ccccatccgc tgattgaaaa
     1801 ggaaaaactt tcatgttaaa atatgaaaat agaaaaacag tccgcagatc tgaaatcaca
     1861 gacgcggtaa acgataaaag cataaaaaca gaaggaacaa tagaaaatca ttacagaaaa
     1921 gttacctgag aaaggaatga tcagaaagaa tggaagagac ttgcagcagc tgttgcacag
     1981 gactgattca agaggggccg gagttcaatc tccattttgc cgattatggc tggtgcgctt
     2041 acgacagtat cagcgaggaa ctggtccacc gggcgaatct ggtatacgag gaacagggga
     2101 tcgaggcggc ggagcggatt ttgattgagt attatcagaa tgaagcgccg ggacagattg
     2161 accacatttt aggcgcggct ccttcctttt ccatgcggga agggatgatc cgccagtgct
     2221 ttgaggatca cagagaagga aggtactacg ccagcgttcc cctgtctctc atcatcatcg
     2281 acggggcagt caatgactac accaagaaaa agggattttt cactgcggcc actacagtgg
     2341 atccctggga ctgcctggtg ggatgcaccg aggggctgac aaaaatcaag ctgaatttta
     2401 accagaaccg tttaaagaca aacagcgatc ccatttacat tccctacagg aacggaattc
     2461 ttcatgggcg cgatatcaac tacggaaacg agtatgtttc ctgcaagtgc attgctctga
     2521 tgttcgccat cgccgactgg atgatacgaa gaaccgccag agaggaagga ctcctgccgg
     2581 agttagagct ttaagccatg aaaaatcggg acagagggca gaaaggacgt taaatgagaa
     2641 gaaaaagtga caaattattt ttgacagcga tggcggcggc cgtcatgacg ctgagttccc
     2701 tgggaggaac ggctgcttct ttcgctcagg cggcccagag ccaggcaggc cagccggaga
     2761 aaatggctgc tggaccagct ctggaaagta tggagaacag caaggcaaag acagaagcag
     2821 tgggagagac agcagaaggg agagcctccc agacttccta tgaagaatat ctgccggcac
     2881 agtttgacat caatacgctg aaggcagcag aggaaacgga tcacctgatt ctcgcggtgg
     2941 gagacggagc ggatcagagc agtctgactt tatggtatta tgaaagaggg acagacggcc
     3001 gcctttcaga ggtgttcgga acaaggggaa cctgcggccg ggccggaatt acggcagata
     3061 aggtggaagg ggataagaag actcctgcag gactttactc ctttttgatg gcttttggac
     3121 tgaaggacga tccgggcagc cagatttcct accgcaaggt gcaggatggg gactgttttg
     3181 tagacgatgt gggaagcaga tactacaatc agtatgtaaa aggcggggag gcacaggcgg
     3241 actggcgttc tgcggaagtg ctgaaaaatc agggctcctg ctacaattat gctctggtac
     3301 tggattacaa taaggactgt gttccgggaa gaggatccgc cattttcctt cactgcccca
     3361 aggtggtcaa cgacacctac acagccggat gtattggaat tccggaggag cggatgaaga
     3421 caattctcac ccgcgccaaa gcagacgcta aaattctgat tgtgccggac aaggacgggc
     3481 tttcagagta tataaaatag gaaaaagcag aaaaaaacag aaaccttccg ccagttctaa
     3541 acagagcaga accggcggaa ggtttcttcc attttgacga ccagagcttc aggagaaatt
     3601 cctcttagag aagcgatggt atcaatgctg tgatttaata cagctttgat gtcattccag
     3661 ggaggaagcg gccttttgca gaaggaggcc tgttcatagg cccacttcac ggcagaacag
     3721 ccgtccgttt ccactaagag tctgttttcc ggcgccagga cggcagcctt ctggactgca
     3781 ggctggtaga aaacgtcagg gcctatggtg aaatagcagt ccagatccag aaaatcggaa
     3841 agcccttccc cgccggaata ccagtgaacc aggtaggtgt ttggatatgc cctgatcagg
     3901 cgggcaatct gtttttcctg ccccttggtg tgcaggacca ccggtttttt catggcagag
     3961 gcaagctcca gctgggcgca gaaagccttt tcctgaacgg agagagggac gctgcaccag
     4021 acgttgtcca gtccgatttc accgatgaca gaggccttta aaagccacgg ttccatggcc
     4081 cggaaggata tctgatccgc cttccagggg tggagtccaa aggctggacg gataacagag
     4141 gagagggagg gatcggctgc cagctcttcc agctgctttg cttcctccgg atcggtggcg
     4201 cagatgaggg agagaatgtt ctgttttttt ctgagtgtca gttcttcggt agtcccgatg
     4261 tgggcgtggg catcgtaaag cgcagtcaat ggatttcctc cctgtggttt tctacaattt
     4321 tttcatagat ggtctggcgc agagctccct ggctgtagag ccaggagcgg gttctgtttt
     4381 tttctgagat ggcagtttcc caggtgatcc gggccgggga accgtttaaa atcaggattc
     4441 gatcggacag gtagatggcc tcgtccatgt cgtgggtgac taacagcacc gtacggttca
     4501 gccgctctct catggacaga agccagtcct gcatttcccc cctggtaatc acatccagag
     4561 cgccgaaggg ctcgtccaga agaagaatat cggcatggca cagagctgtc ctgagaaaag
     4621 cggcccgctg tctcatgccg ccggacagag cgtcagggta cttgtattcg tagcctgaca
     4681 ggccgaaggc gggaaaatgc ttcagagcct cctcccgcgc ttctttcagg aagccgtgga
     4741 tccggccgta gagacagaca ttgtccagaa tatttttcca gggaaagagg agatcattct
     4801 ggggcatgta ggcaaaatgt tcagccggat gagagatttc tcttccgttt gccagaagag
     4861 agccggattc ctttttaagg actccggtta agagctttaa aatcgtagat tttccgcagc
     4921 cggagggccc caggatgctg acaaactctc cctccctgac ggagagggag agctggtcca
     4981 gcactggctt gtcctcatag gaaaagctta aatcagagat ttctaatttc atggcgttcc
     5041 ctttccaggc ttatttgcct gcgccaggca gaaattcatt ggtatagcag tcagaggccg
     5101 ggatagtcct gtcaatgact ccgtattctg ccataaaatc ggtgtagtta tcccaggttt
     5161 catcggtcat cattccccac acgtctgtgt cctccatata tttgcctgcc aggaactcct
     5221 gagattttgt gagcatttcc agggagtagt caggcgcgta cttgtggagg atttcagcgc
     5281 tctcctctgg atggctgata gcgtactgat agcctttttc cgtggccttt aagaattttt
     5341 ttaccatttc cgggcgctgc tctaaggtgt cgtttccggc aatgatgaca ggcgtgtagt
     5401 agtccagacg gtcgtccagc tctctcacag gcatgtagtt gatggggaag tggttcatct
     5461 cgcaggtaat attgtcccag ccctcgaaaa accacatgat gtcagcctga ttttccaagg
     5521 ccgcgaagcc ggatccgtcg gaaaccacca tatttaattt agaaaagtct gcgcctgcct
     5581 gggtcatcac tgcttccagc acagctgcct cgcctgggcc gccccagcct gcgtaggttt
     5641 taccctcgaa atctttggga gacgtaatat ttttatcagc tgcggtaaca aagccggagg
     5701 tgttgtgctg aatcagggct gccacagctt tgatgggaag gggctcctcg gaagtcaggg
     5761 caatggtgac gtcctcctga taactgatcc caaagtcgcc ttttcccacg gctacgagag
     5821 tggcggtagc tccctcggta ggctccacaa ttttgacgtt caggccttcc tcttcatagt
     5881 agcccagatc cagggccgcg tacatgccgg tgtggttcgt atttgccaca tagtccagga
     5941 tgacagttac gtcctccaga ttttctttgg aggaagcggc ctgggacgac tccgtcaggg
     6001 aagcgtctgc gcctgctttt tctgtctccg cctgggaagc agccgcgctg gactgggaag
     6061 ttttggaacc ggagcaggcg gtgagagaga ggacggcgag agccgccaga cagagagctt
     6121 ttaaatgttt ctttttcatg gtaaatctcc ttattaaaat taaaatagtt tatatcgttt
     6181 ctagtttatg aggcagagct gcggcttccg gcctgtgcct gacggtggcc ggagggggat
     6241 acgatccggt ttgccagcca caaggccaga ttcatgcaca ggcttaaaaa gataatgacc
     6301 aggacgcagg caaacacctt gtccagcatg tatccgtttt taacgcgcag caggtagtag
     6361 cccagccctt tttgagcgcc aatccattcg cccaccacag cgccgctgac actgtaggta
     6421 gcggctactt tcaggccgga aatcagggag ggcacagccg ccgggatttt taccaggcgg
     6481 taggcagtcc acctgctggc gccgaaagag cgggccagat gaagatattc cggatccagc
     6541 tgagccatgc cgtctgtgaa actgaccgca atgggaaaaa aacacataag cactacagtc
     6601 agaatcttcg gagccaggcc aaagcccaga tagataatca ggatgggagc caggacaatc
     6661 atggggacag tctgggtaac caccagaatc gggtagacta cctgcctgag gggggcgaag
     6721 gcgtccataa ggattcccag aacaactgcc agaaccagag aaatgcccat gcccagaaga
     6781 gcctcagcta cggtgatcac gctgtggctg aaaagcgtaa gccgatcaga gataagggcg
     6841 tttaaaactt ccgtagggga ggggaggacg taaaggggaa tctggaacag gcgcacagcc
     6901 gtttcccaga aaatgagaac tgcggccaga gcaagaacag gcgcggcgcg tttggcatat
     6961 gacatataga agaagctcct ttccagctgt ctgttacctt ctgatgagaa aggcagacgg
     7021 acagtcttga cacaggagcc gcaaaaagaa accctgccgg gtaatggcag ggtgaaaata
     7081 cagtgttatt tccctacgtt ggcattatcc aagtcaggtt ctaggtcgaa attcgcaatt
     7141 tcctctcagc ctgtttacaa gctccctgtt gtatataaat atgtaacagg attgatttta
     7201 acacaggaag gaatatttgt aaagaaaatt ggagatgcca ttcattatca ggggcagcgt
     7261 atgttttggt aagtgcgggg aggtgctgtg agagaaaaag aaggaaaagt cagaaaacac
     7321 ttgattttta ttcggaaata aaatataata ataacagtta ctaagattgg ttcgtaagga
     7381 ggaaatgaaa tgagtctgaa attttatgtt tgtcagcatt gcggaaatat tgttactttt
     7441 gtaaaggacg caggggttcc tgtgatgtgc tgcggcgaga agatgagcga gctcatcccg
     7501 ggaaccagcg atggcgctca tgagaagcac gttcctgtcg tagaggcaga gggaaagaag
     7561 attacagtga aggtaggaga ggcagagcat ccgatgttag aggctcactg gatccagtgg
     7621 attgccctgg agactaagaa gggcagccag atcaaatatc tgaacccagg cgagaagccg
     7681 gaggctcagt ttattctcag cgaggacgac gaggcagtgg cagcttacga gtactgcaac
     7741 cttcacggac tctggaagaa ggagatctaa aataaaaacg gcgttcagcg gttttctttg
     7801 acaaaagagg gaggaagcgt tttccactgc ctttggcgga gcaggaaaat gcttcctccc
     7861 tttctgcgtt tattttttct tccctcccag ttttttagag agagttctga gcatttctac
     7921 ccgctttttc tcagcgggac tcatttttgc cgtcataatg gataccagaa gatctgtttc
     7981 cgagtctgta aactgaaact ggccggaacc ggcggccatg ctcataaata ggggcatcag
     8041 cttgtcttta ggagtctgtt ctaccgtttc cgccagtttt gtcaaatagt ttaacttttc
     8101 ctgattcatg gtttttaatc ttggatcctg tttccaggct gcgttcatat cgatccatcc
     8161 tttcctttta tatgccctgc atggtctgca tgagaagctg ggccgtttcc agctttgact
     8221 gctgctctgg gggcagcatg tttttcagat gctcaatgga aaaatgcggt ccgcctctga
     8281 ggggacggct ggaggagccg cgcccgtctt cctcatcccc gcatacgctg cttttttcgg
     8341 cttctgccgc gcctgcggga ccgtcctccg cagatgctcg gtaggactgg taaatccggg
     8401 agccttggag aaaatttaca atcagatcaa taaattcctg ctcctcggac gttccgtagg
     8461 gcttcatggc gtttaacata tcgagcggtg aatcggaggc gttttcctcc agagagcaga
     8521 tacctaccat gccgtcctcc ttctgctcaa aaagcttcat ggtgcggttc agctcactga
     8581 gctttacgat catggaaaaa aagcgctgct ccggcacatg tatgtaggga agggcggctt
     8641 tgatcatctg caggtggggg gaggcggtca gataatctaa atccgtcatt tttaaatcag
     8701 attccgtttt catggaaata acctcttttt gggaattctt ttttaaccca atatatgcaa
     8761 agctgcctga aaacatgata cagggaagaa agctgcctcg tccgcagcgc gaagacgtca
     8821 cagcctgttt tggaaaagca tataataaag cagatgggag gtaaaaacag tgggaatccg
     8881 tttaattata gaaggaaaca cagcgtatga aattgacgaa gactgtctgg cagccagaca
     8941 ggaaatctgg gacagcgatt ctgaggaaaa gccccgggaa aatcaggagg aacgccgccg
     9001 cgcaaaaaat tagatcaaac cgctccccta tttttctgat tgtcctgaca gaggatttat
     9061 gataaaattt aagaaagagt taagagtaga agaagaattt caactgactg aaaaataaga
     9121 aacagacgcg gcgcagaagc ccggaggccg gacaaggctc cgggcttctg tccggatgat
     9181 aaaaggaggg gatcctgtga ttcattacaa ccactttatt atggcagaga gtctggacga
     9241 ggcctatgag ctgaaccgga aaaagtcggc tgtgatctgc ggcggcttct gctggctgag
     9301 acttcagaac cgcacagttc agacgatgat tgatttaagc ggtctggggc ttgaccagat
     9361 tgaggagacg gaggaaggat tcgagatagg atccatggtc tccctgagaa agctggaaac
     9421 tcacaagagc tttcaggcat ggacaagggg ggcgggagct gacagcctgc ggcacatcgt
     9481 gggaacacag tttagaaact gcgctaccgt agggggcagc atctacggcc gctttggttt
     9541 ttcagacgtg ctgacgctgt ttctggctct ggacgcccag gtaaagctgt ttaagggagg
     9601 cgtgcttcct ctcagagagt ttttagaccg ggaggaggac ggagatattc tgctttctgt
     9661 tctggtgaaa aagggacagg cttttgccgc ctatgagagt atgaggaacg aggcggtgga
     9721 cttcccggtg ctgacggcgg cagtctgtct gagagacggc cagtttaccg tttccgtggg
     9781 ggccagacca ggaaaggcaa gagcatattc agttcctgag acggaacttt caggggaagc
     9841 ggatcagagg gacgaggcag tgaaggcgct gacagagaaa tttacatatg gaacgaatat
     9901 gagagcttcc gccgagtaca gaaaatatct ggcaggcgtt ctggtttcca gatgcctgaa
     9961 ccggatcgaa gcagacagga aggaggaaac gtcatggaat taaaatgcat cattaacgga
    10021 tgtccggtgg cagccgacgt ggcggcggat ctgtctcttc ttcagtttct cagagcgcag
    10081 ggatacaaaa gcgtcaaatg cggctgcgag acgacaaact gcggcctctg tacagtctgg
    10141 ctggacagca ctccggtgct ttcctgcgct gtgccggcca tgcggactca gggacgccag
    10201 gtgacgacgc tggaggggct taaagaagag gcggaagaat tcggccgctt tctgggagag
    10261 cagggagccg aacagtgcgg tttctgctcg ccgggattta tcatgaacgt gctggctatg
    10321 gagagagaat ttgatacgat tccttcttct gatgaaatac gggaatatct gtccggaaat
    10381 ctctgccgct gcactggcta tgcgggccag atgcgggcga tcagaaactg gctggaatac
    10441 agaaaaacaa agaaaggggg agatgcttca tgcagaaaac agtagatctg gaacaggaaa
    10501 acagactgcc tgattttgga aaaactgtgc gggaggacaa ggaggagcgt ttgagaaaac
    10561 agggctttgt cacccgtccg actatgaaaa aggacgccat ggctcttatg acgggacgtc
    10621 cggtttacac agacgatatg gctccctctg actgcctgat cgtgaaggcg ctgagaagcc
    10681 ctcacgctca cgcgctggta aaggaaatcc acacagagca ggctaagaag gtgcctggcg
    10741 tggtttgcgt gctgacctgg aaggattctc ctcagcttcg ctttacccag gcgggacaga
    10801 cctatccgga gccaagcccc tatgaccggt atattattga cagaagagtc cggtttgcag
    10861 gagacgtggc cgccattgtg gcagctgaaa cggaagcggc ggcagataag gccctgaagc
    10921 tgattcaggt ggagtacgag gttctgacgc ctgtgctgga ttttcggaca gcgaaggaca
    10981 atcccgtgct ggttcacccg gaggaggact ggaaggctct ctgtccggta ggagcggaca
    11041 ataagagaaa tctctgtgcc agcggcagcg aggaggaagg ggacgtggag ggaacctttg
    11101 cgcgctgcga tctggtgata gagcgtacct accacacaaa ggccaataat cagacaatga
    11161 tggagacctt tagaagctat acgttcctgg acgcgttcgg acgtctgaac gtggtttcct
    11221 ccacccagat tccgttccat atcagaagga ttttagccaa cgccctgggt attgaaaaat
    11281 ccagagtccg ggtggtgaag cctcggatcg gcggcggttt cggagccaag cagacaggag
    11341 tttcagagat ttatccggct ctcgtcacca tgaaaacagg ccgtccggcc aggatggtgt
    11401 attccagata tgagtccatg atagcagcgt ctccccgcca cgagatggaa atccgtgtga
    11461 agatgggatt gtccaaagag ggaatggtcc gggccgtgga cgtttacacc ctgtccaaca
    11521 caggcgctta cggagaacac ggccctacaa ctgtgggatt gtcaggacat aagtccattc
    11581 ccatctatac gccggaggcg ttccgctttg cctatgatgt agtttacacg aatcatcagt
    11641 cctccggagc ctatcgggga tacggggcga ctcagggact ttttgcagtg gaatctgcct
    11701 taaacgaggc ggccgatctg ctgggaatcg atcccctcgc tatccgcagg atgaatttcc
    11761 tgaaggaggg ccagattatg ccggcctatt accatgaact tctggaaagc tgtcacgtgg
    11821 aggagtgcat ggatcgggcc gccaggatga tgaactggga agaaaagttc cccaggcgcg
    11881 acatgggcaa tggcaaggtc cgcggagtgg gagtgggcat ttccatgcag ggctccggca
    11941 tctccggcgt ggacgtggga actgtgtcca tccgtctggc agacagcggc cactacaata
    12001 tgatgatcgg cgcgacagat atgggaacgg gctgcgatac gattttagcc cagattgcgg
    12061 cggactgcct ggagtgcgat gtggatcaga ttgtggtttc cggtgtggat acagataatt
    12121 ctccctatga ttccggatcc tatgcttcca gcaccaccta cataacaggt atggcggctg
    12181 tgcaggcctg cggacagctg agagagaaga ttgtgaagaa gggatcagac atgctcggcg
    12241 cagatccgga acagacggac tttgacggcg cgtttgtcta tgtgctgggg gaggaggaaa
    12301 gaaaagtttc cctggcggac atttccacca gaagtatgtg cggaaacaat atgactctgg
    12361 aagcctcggc atcccactct tcccctaaat ctccgccgcc gtttatgtgc ggaatggcag
    12421 aggtggaggt agatctggct accgggcaga tcgaggtagt gaactataag gcggctgtgg
    12481 actgcggaac agttgtcaat ccgcctcttg ccagagtcca ggcggagggc ggcattgtcc
    12541 agggaatcgg aatgacgctc tacgaggata tcaattatac agagaagggc cgtctgaagg
    12601 agaattcctt tatgcagtac aagattccgt ccaggctgga aattccggat ctgcaggtgg
    12661 agtttgaatc cagctacgag cctacagggc cgtttggcgc caaatccatc ggcgaggtgg
    12721 taatcaacac gcctgcgcct gccattgccc aggcggttta tcacgctaca ggcctctggt
    12781 tcagggagct tcccattacc ccggagaaga ttatcagagg actgggaaaa ctgaaatgat
    12841 cttttgtatt cttctggctt ccgggctgtc caggaggttt cagggagaaa ataagctgtt
    12901 ttaccaggtg gagggactgc cgatgtaccg gcgggtcctg tcctgtgcct gctgtgtgag
    12961 agaagaactg aaggcagagc agggatggga ggtgcagatt gttctggtga ccgcttatga
    13021 ggagatcgcc gcagaagcag ggaaggcctc cgctctcgct gtcagaaaca gagagccgga
    13081 ggcagggatt tctcactctg tccgcctggg cgttcaggcg gcggatccaa aaccggacga
    13141 ctggctgctg ttttctgtct gcgatcagcc atggctgaga gcagaggagg taaaggctat
    13201 gattacccgg acgatccggt caggaaaggg gatcggagct ctgtcctttc agggagagcc
    13261 gggcaatccc gtcctgtttc ggggggatta ccgcggggaa ctgtgcgctc tcctggggga
    13321 tcgtggcggc aagtcagtgc tcagaaacca tctggaggac gtggttctga cagaggtttc
    13381 caatgcaaag gctctttcag atgtggacga gaggcctctg gacggcggcc tgtaaccgcc
    13441 ggtccgaacc gctttgcccc gttttcctga cagccgcctt ggcgctaaat ttccttcatg
    13501 gccagaacgc tgttctgata ctcgcctgta aaggtaactt cgcgtccaaa ccaggtggga
    13561 ggcacaaacc ggtctgcctc ctcttttgag gagaattcca cctctgccag aaccagcccc
    13621 tgataagctc cttcaaatac gtccagctca atggtaagcg gagaggctgg aatgcctgcg
    13681 tcctttgcgg gaatgagata ccgtttctta gtgagaacca ggccgtcggc ctttgccagc
    13741 agatgggcgt aggactgggc gtttaagggg agattgtact cttctctggc cattttcccg
    13801 cgggatttgt aggtgagata gaaggaatcg tcctgcctgc ggatccgcac caccggatcc
    13861 acagacagat aggcctgctc gatctgcaga aacggatagg aaagacagtt ttccggcatt
    13921 tctgcagctt caatgagata ctttcgttcg atttccatat agttgcgctc cttgattcat
    13981 gatttaacag aggttattat accacattca gcccccagtt tatcacggtc agtagatatt
    14041 ctgaaaaaag aatggtataa tatgaacact tggcgaggtt tttcacgagt ctagtgagaa
    14101 tatatacctg tcccacttag cgaggtcttt tcgagcttag tggacatggt ataataactc
    14161 caaaatgcag ctgtgcttcg cacatctgcc gctgcctctg gcagctgaga cattttgtcg
    14221 ttaccatatc aggtgaaaac aaatgtctgc tttgcagccg cttgttttcc tgctgatatg
    14281 gtataatatc gtcagacgaa acgatatatt gtgcaggaaa cagaggagga aaacacatgt
    14341 ggtcaatcag cgaggtgaag aagagaggct ggaggcagat tggtatgtac tactggccgg
    14401 cgtttcttct gcttatttta ttcggcatag ccgcccgttt tgagaattcc atgaacattc
    14461 acatggaacg ggcagtttac tggatcgttc aggagggcct ggttcacggg ctgcttcatg
    14521 gcggattgct gcatggcttt gagctgccgg acttcggata tatggcggag agcttttttt
    14581 acggagtgct ggctttatcg gggcttgtgg ggatcggcat taaaatattc atcgtcaatc
    14641 ccatggaggt gggatgtaaa cgctttttca tggaaagcag ggagcttgac cgctcggcgg
    14701 gaatcgacag gcttcttttt gcatttatat ctggaagcta tctgaatgta gtaaaaatta
    14761 tgtttttaag ggatttgttt attgcgctgt ggacgctgct tttcgtcgtt ccgggaattg
    14821 tgaagagcta tgagtatgcg atgattccgt atattttatc ggagaatcca gaagcggatc
    14881 agagagaggt ttttgccgcc acgaaggaaa tgatgcaggg aaataagttc cagctgtttg
    14941 tatttttctt ttcctttatt ggatggcttt tcctgggaat tctgttcttt ggaatcggca
    15001 tgctgtttat caatccctat atccgggcgg cagaagcgga ggtttacagt gaactcagaa
    15061 gacatacagg tatgtacctg aacggatttt atgaaaaaca ggaggaaatg taatggcaga
    15121 ggtttatgcg tttttagcgg atggtcttga ggaggtagag tgcctggcgg cagtggacgt
    15181 gctgatccgg ggcggtgttt cggtaaaact gatttctatt tcagacagga gagaggtaac
    15241 aggttcccat ggctttcgga ttacagccga cgcggttctt gacgaggtag atttagacgg
    15301 ggccgacgcg tactttctcc cgggcggcat gccgggaacc actcagctgc gaaactgtga
    15361 aaagctgtgc ggcgctcttg tgaaggcggc gggagaggga aaacgcctgg ctgccatctg
    15421 cgcggctccc agcgtgtttg gagagctggg ccttttaaat ggaaagaagg ccacctgcta
    15481 tcctggcttt gaggaacact taaagggcgc ggtttacacc tcccagggcg ttgtgacaga
    15541 cggggcggtg accacggcca gagggctggg ctatgcgctg gatctgggaa tcgagctttt
    15601 aagccttctc acctccagag agaatggcca ggcggtgaaa gacgccatcc agtacgacca
    15661 gcattaaagc cggagaaatt cagaaaaaac aaggaaaaat ataagaaaat ctcgtgaaaa
    15721 gccatatttt ctactggcgt ttacgtaata catatgatat aatgctatct tgaagtgtaa
    15781 cgcccagatg atacggcggt tcacatatat taaaggagga acccttacaa tgagtttaca
    15841 ggtagaaaaa ttagagaaaa acatggcaaa acttacaatc gaggtgtccg ctgaagagtt
    15901 cgagaaggcg atgaaggcag cttacaatca caataaagga agattcaaca ttcctggttt
    15961 cagacgcggc aaggctccgc aggccatgat cgagaaaatg tacggcgcag gcatcttcta
    16021 cgaggatgct gcaaacgcag tgatcgacat gtcctacccg agagagttag aggcatgcga
    16081 ggaggagatc gtttcctctc ctgagatcga ggttgttcag attgagaagg gcaagccgtt
    16141 catctataca gctactgttg cagtaaagcc tgaggtaaca ttaggcgagt acaagggagt
    16201 agaggttgag aagacagacg ctgccgtgac agacgaggat gtggagaacg agttaaagaa
    16261 cgttcaggac agaaactcca gactggttgc cgtaacagac agaccggttg ctgacggaga
    16321 tcagactatc attgatttca agggctatgt agacggcaag ccgtttgcag gcggagagag
    16381 ccaggattac ccgcttacta tcggatccca ctccttcatc gacacctttg aggagcagat
    16441 gatcggcatg aacatcggcg agacaaagga gcttgaggtt actttcccgg aggagtacca
    16501 cgcaaaggag ctggctggaa agcctgccaa gttcgaggtt aaggtaaaag agatcaaggt
    16561 aaaagagctt cctgagttaa acgatgagtt tgcaggcgag gtttccgatt tcgagactct
    16621 ggctgagtac aaagaggact taaagaagac tcttacagag agaaaagaga agacagctgc
    16681 cgctgagaac gagaacaagg taatcgacaa ggttacagac aacgctcaga tggatattcc
    16741 ggaggctatg attaagacac gccttcgcgg catgttcgat gactatgcaa gaagacttca
    16801 gagccaggga cttgacatta accagtacat gcagttcaca ggcatgacaa gagagaatat
    16861 catggatcag atgaagccgc aggctgtaag acagatcaag acaggccttg ttctggagaa
    16921 ggtggctgag gttgagaaca tccaggtaga ggaagcagct gtcgatgagg agatcgcaaa
    16981 gatggctgag gcttacaaga tggaggctga caagttaaag ggccttctcg gtgagcgcga
    17041 gctggagcag atgaagaagg atctggctgt taagaaggca gtagagcttc ttgtggcaga
    17101 ggctaagtta gtttaatctg caaaagctga gaaacgaaat caagacaaac acagggcaga
    17161 gggaggccgg attttttcgg catccctgtg ctttttgtca taacgacgag gaagatttgc
    17221 atagagaatc ttgctctgt
//
LOCUS       DBMDUW010000055        16542 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_2002_length_16542_cov_3.486284, whole genome shotgun sequence.
ACCESSION   DBMDUW010000055 DBMDUW010000000
VERSION     DBMDUW010000055.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 16542)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 16542)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16542
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2002_length_16542_cov_3.486284"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            111..308
                     /locus_tag="ACZPCR_09730"
     CDS             111..308
                     /locus_tag="ACZPCR_09730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HIR1231191.1"
                     /translation="MELMVSGLSTLIVGLMVAGIVFLAVRSIVKDRKNGKSLCGGNCG
                     GCSCSGMCHPKREGQKNQIQN"
     gene            complement(388..936)
                     /locus_tag="ACZPCR_09735"
     CDS             complement(388..936)
                     /locus_tag="ACZPCR_09735"
                     /inference="COORDINATES: protein motif:HMM:NF025702.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4397 domain-containing protein"
                     /protein_id="HIR1231192.1"
                     /translation="METYNYDPSAQAGSEARTAENESAVYHRPGSGSVSDPNTAPGFG
                     PAGPVTPSLPGNTGGCINCGPGQGGLSNLLGNVLWAWGSFPSVSPSGIAHVRFYNAAS
                     IREPLDIYLNGRLVVSDLDYMNFTRYLHIVPGNYLLTVYQRTNPGGEPIINNRVQFQA
                     GNYYLLSILGGPYDYSAQLVIS"
     gene            1079..2359
                     /locus_tag="ACZPCR_09740"
     CDS             1079..2359
                     /locus_tag="ACZPCR_09740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HIR1231193.1"
                     /translation="MKEQKKARASALLPILVFLLIFLGSGFLTGDFYSMPAIVAFLIA
                     LFVAFIQNRSLSFADKIKLAAQGVGEENIITMCLIFLAAGAFSGAVKAAGGVDSTVNL
                     GLSILPSNVAVAGLFVIACFISISMGTSVGTITALAPIAVGISEKTGFSMAVCAGAVV
                     GGAMFGDNLSMISDTTIAAVKTQGCEMKDKFRENFLIVLPAAILTMVLFLVLAKDADY
                     QMEYELSYNVFKVLPYLVVLIGALAGVNVFIILLAGTVLSLIVGVATGAFTVAEMFTH
                     VGAGITGMYDITVISMIVACIVALVKEYGGIEFVLSFIKKRISDERGGELGIAALSLV
                     VDMCTANNTVAIVMAGPIAKEISDEFGVTPRRSASLLDMFSSMGQGLIPYGAQLLAAA
                     SLTGLTPFEIIPYCFYPILMGLSGLVFIFMKKRK"
     gene            2375..3703
                     /locus_tag="ACZPCR_09745"
     CDS             2375..3703
                     /locus_tag="ACZPCR_09745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HIR1231194.1"
                     /translation="MKAHNQWASKLGFILATAGAAVGLGNLWKFPYLMGRNGGFFFLI
                     AYLIFICILGIPVMITEMSLGRKTRHDPVQAYADIHPHARVVGIFGVLAAFIILSYYS
                     VIGGWILKYIVSYATTFDAPADFNAFISNGAEPVLWHFIFMLATTVICYKGVSGIEKV
                     SKFMMPMLFVLLLIIIGRSVTLPGAGKGLAFVFTPQESTFTLGSITAALGQVFYSLSL
                     CMGITITYGSYLNDKENIPKSCASVAGLDTTVAILAGIAIFPAVFAFGLEPGQGPGLI
                     FGTLPKVFGSIGGGAIFALAFFALVFFAAVTSAIALLEVSVSFAIDTLKWKRKSATLI
                     IGTLIFLLGIPSALSFGVLGDVVIANYSVFDFVGMITDNILLPCGGLTMCYYIGWKWK
                     PEYLVEEIEKNGVGFKLKKLWILCIRFLTPVLVGVVTISGLVSVYGVVFA"
     gene            4204..5883
                     /locus_tag="ACZPCR_09750"
     CDS             4204..5883
                     /locus_tag="ACZPCR_09750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5722 domain-containing protein"
                     /protein_id="HIR1231195.1"
                     /translation="MRHLKWMKAAASTAVFACLFAGTVFAADSEDLSSCVVDGNQIKI
                     TGTAVHTEDEGQGEAGQKTETADDGKYYLFDLMPYETSLEGRSDYLAAADKTESLSFA
                     LPFDKNQNEDPLFARYVVAVNRGGVYEPVSNEAYVTNPEVTSDYQEPFPEAQTKKGLN
                     IELSMLDDAMSLGVKHTAINISVREFLDPNGALTYDYNGKTYRFNKSRVEEYDKTIRM
                     FSNKGIIITGIILNGWNTSHPELLYPGVKETGTSQYYMFNTSTPEGFETCRAVMAFLA
                     ERYNGSDPNYGQVSNWIIGNEINNQEIWNYTGPMPLEEYVAVYERMFRVMYAAIRSEN
                     ANARVYFSTDYNWVQENKTLSYGARDLIDCFSSQIKKGGQIDWNLAYHPYPVNLQEPE
                     FWLENEKVTDSVDSKVVNFKNLHVLTDYFQRPELLNSAGQVRHIILSEQGFTSQSPAR
                     GNVEKEQAAAFAYAYFLVDSNPYIDSFILSRQVDNPHEASLSMAFGLWTANPNSPANA
                     APVGFDRKRIYPIFKIIDSRKAVEETEDLKAVIGINKWSDVVPNFRWGTNN"
     gene            6107..6481
                     /locus_tag="ACZPCR_09755"
     CDS             6107..6481
                     /locus_tag="ACZPCR_09755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6465 family protein"
                     /protein_id="HIR1231196.1"
                     /translation="MAAPRKRTAAKTAAKEGKDQAVSAAETVLEAAESGKTEAKKLAA
                     KRSTARKTAAKKEVKAQVFVQYLGKEISADSLVEEAKKAFVAAGHKESEIETISVYVK
                     PEENAAYYAVNGAGSEEYRIQL"
     gene            complement(6545..7159)
                     /locus_tag="ACZPCR_09760"
     CDS             complement(6545..7159)
                     /locus_tag="ACZPCR_09760"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231197.1"
                     /translation="MFFDFFGYFAIPFLAAALARETDLFATNFSSIRTASHRQGEFLL
                     WSLSLLVYLFLCILPLCCRLQDQGRRPGANGFFRKKQPFPVVFFFLFPAVLLLTAVFT
                     PYLPEEEPFWSQVHVYTCVWSSVSFFILLALSVLPVYFHASSRREGRALLCLLILNAA
                     FCAASYLITGIVNSAMEIFYTFVCCVCANRLRLFFSRPVLKKII"
     gene            7276..8730
                     /locus_tag="ACZPCR_09765"
     CDS             7276..8730
                     /locus_tag="ACZPCR_09765"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HIR1231198.1"
                     /translation="MMELPQAFKEKMERLLGAEYTEFLESYEKERKQGLRLNLLKTSR
                     KKFEQEAPFSLSPIPWTEEGYYYGKEDRPGLHPYHEAGVYYIQEPSAMAVVSLLDPKP
                     GERILDLCAAPGGKTSHIASRLQGRGFLAANEIHPARAKILSQNVERMGIGNCAVFNE
                     TPDRLLRHFPEYFDRIVTDAPCSGEGMFRKDEAARGEWSPDNVKLCAERQAYILDCAA
                     GMLKPGGTIAYSTCTFSPEEDEQAVEAFLDRHPEFHIKEVKKPEGLSGGVPQWGAKER
                     PELARAVRIWPHKTGGEGHFIAILEKEKAEGWEDGRKRTYPAYWKDRKALRDYESFLK
                     ETIADLGEDSALSRLLDGRELTLNGEQLYLLPPELLSFDGLKVLRPGLHLGTMKKNRF
                     EPSHALALWLGEKDALRFCRMNPDSPRLAAYLKGEAVSLSQLAEEESVQGAGPADKGW
                     TFVTVAGNGSGYPIGWAKLAGQTLKNHYPKGLRR"
     gene            8836..9519
                     /locus_tag="ACZPCR_09770"
     CDS             8836..9519
                     /locus_tag="ACZPCR_09770"
                     /inference="COORDINATES: protein motif:HMM:NF018837.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HIR1231199.1"
                     /translation="MSDINKTNGSAETPETEKKPAEKKTAAKKTSEKKAAEKKTTTKK
                     TAEKKTASRKTAEKTAPKKAAEKQPEKKKVNEKLIEALSQWEKNPSRENLNAVMEEVV
                     MTGKFLVPAVTAELTEEESRKVGSGKGKKMRFTTFTNAKGQKYFPAFTSPAQLLLWDK
                     EYKGETAVLTFDDLCSVVGWNPDMLGFVVDPFGANLSIGGELCGQLKRKKDLLRKQYA
                     ELVRKNLKR"
     gene            complement(9652..10608)
                     /locus_tag="ACZPCR_09775"
     CDS             complement(9652..10608)
                     /locus_tag="ACZPCR_09775"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HIR1231200.1"
                     /translation="MKQTFTYQITEQDQGRTIEQFLRLRGFSRRLLVRLRKTDHGICL
                     GAGGETPVYTTKILSEGDLLTIRVPDDSPSGHIVPVKQEFTILYEDEDLMVIDKPAGM
                     PVHPSQGNFYNTLANGVACYFAQKGESFTFRAVNRLDRDTTGLLIIAKHLLSAALLSE
                     MVAKKQIRRQYLAAVSGKTEESGSVCAPIARADGSTIERCVDEERGEYACTHYQRLYY
                     CPEKDCSLILLSLETGRTHQIRVHMKHIGHPLYGDFLYHPDYRFIGRQSLHSFRLSFS
                     HPLTGKEMTFEARIPDDFSFAVPDGCSVSGCPAPSGRPDRQA"
     gene            10738..12069
                     /locus_tag="ACZPCR_09780"
     CDS             10738..12069
                     /locus_tag="ACZPCR_09780"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HIR1231201.1"
                     /translation="MKQESRRKGAKSREMKGALLGIGLAALAVSLPGMEAEKTAANLK
                     QPLCSSLAELPKGTGEEKEQPSFSLHAQSAVLMDAETGRILYEKDGETRRPMASTTKI
                     MTCILALEEGNPEDLVEVSACAASMPDVQLGIREGEKYYLKDLLYSLMLESHNDSAEA
                     VAEHIGGSAEGFADLMNQKARDIGCEDTCFVTPNGLDKARESDQTPHSTTAEDLARIM
                     RYCIQTSPKKEEFLELTRTASHSFSDESRKRSFYCGNHNAFLNMMPEALTGKTGFTGA
                     AGYCYIGAVRKGEKTFIAALLGCGWPPHKTWKWEDMKRLSSYALKEYEYQEIYDSAKT
                     FPKARVENGVRDAVPLEIRGNGRNSLRVLMREGERPDVRYEYPEKLSAPVKQGDPVGR
                     ADYYLGETLLSSYPICAAELVEKRTIWLCLKTCLSRWMNVPETSIKIFHFF"
     gene            12149..12739
                     /locus_tag="ACZPCR_09785"
     CDS             12149..12739
                     /locus_tag="ACZPCR_09785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HIR1231202.1"
                     /translation="MDAGISRAEAAELLKKYNKEPFHILHGLTVEGVMRWYAEELGYG
                     GEKDFWGLVGLLHDIDFELYPEEHCLKAPELLREAGISEELIHGVVSHGYGHRVEVKP
                     EHEMEKVLYAADELTGLIWAAAKMRPSKSAKDMELSSLKKKFKDKKFAAGCSRDVIRA
                     GADLLGWDLDQLLEKTILAMRACEDEVGRQMEAYNA"
     gene            12755..13774
                     /locus_tag="ACZPCR_09790"
     CDS             12755..13774
                     /locus_tag="ACZPCR_09790"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1231203.1"
                     /translation="MKLLTIAIPCYNSAAYMERCIESLLPGGEEVEILIVDDGSQKDN
                     TAEIADQYEKNYPGICRAIHQENGGHGEAVNTGLRNAQGIFFKVVDSDDWVNGEAYRE
                     VLNTLRRFAHENQRLDMLLTNFVYEKQGAKRKAVMNYRTAIPKDELIDWSSVRMFMLG
                     QYILMHSVVYRTELLRGCGLELPKHTFYVDNIFVYQPLPHVKSMYYLDVNFYRYFIGR
                     DDQSVNETVMIGRIDQQIRVTKLMLGYYDVMKIPNRKLRRYMIRYLEIMMTVSSILAI
                     RSETEENLAKKKKLWQYLKKQNLPLYIRLRWGFLGQGVNLPGKSGRKVSIACYKISQK
                     FYGFN"
     gene            complement(13900..14568)
                     /locus_tag="ACZPCR_09795"
     CDS             complement(13900..14568)
                     /locus_tag="ACZPCR_09795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007708990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HIR1231204.1"
                     /translation="MSSLKKLIKKYGHIWIMAYFAIYLPWFLYLEKHVTTRYHVMHSV
                     VDDWIPFNEYFIIPYFLWFAYIAAVILWFFFTNKEDYYRVCILLFTGMTLSLLICTLF
                     PNGTDFRPYVDPEKNIFAKAVSLLYATDTCTNVFPSIHVYNSVAVHIGIIRSEQFKNN
                     RIVRLISGVLMVSICMSTVFLKQHSIIDVAGALLLCGAVYPLVYAPGAQRSRENDQEG
                     VLIR"
     assembly_gap    14821..14830
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(15009..15815)
                     /locus_tag="ACZPCR_09800"
     CDS             complement(15009..15815)
                     /locus_tag="ACZPCR_09800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008750102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231205.1"
                     /translation="MKRKKLVTVATAICSLLMSSTVFAGTWQTGTGENQGKWWYDNGN
                     GSYTSNGWQWIDGNNDGTAECYYFDNNGWLLTNTTTPDGYSVNADGAWVENGTIQSKK
                     VMNDNEPTQNMAGKYAYYKTQLYVKNEATQSYELYAETPVHEERDYTGYDAVLDERYE
                     LGVGGDFSCFIEIKNAENGTIEYIDDIYGDYIYELQGNEWIRIGNRNIDTKEITIYEE
                     AVKWGIIGFEQDAFSLINKYTGKLINEGHPMNELAGKELMEKTVFKRYES"
     gene            15964..16206
                     /locus_tag="ACZPCR_09805"
     CDS             15964..16206
                     /locus_tag="ACZPCR_09805"
                     /inference="COORDINATES: protein motif:HMM:NF024835.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1231206.1"
                     /translation="MNVKQAVARRIELLCKERSIAYNELANLCGITPSTIYSIFDDKR
                     KNITLSTVKKICDGFEISLGEFFSHPLFDTLEQEIR"
BASE COUNT         4521 a         3561 c         4537 g         3913 t
ORIGIN      
        1 gcattttcta aaattgctca aatccaaaaa aaaggaacag gaacgggaat ataatactaa
       61 aaacacggaa atgaaacgca tagagtttta agctggaaag ggtgactgtg atggaactga
      121 tggtatctgg attatccacc ttaattgtgg gcctgatggt agctggaatt gtctttctgg
      181 cagtcagaag cattgtaaaa gacaggaaaa atgggaaatc cctctgcgga ggaaactgcg
      241 gcgggtgcag ctgttctggt atgtgccatc caaaaaggga aggccagaag aatcagatac
      301 aaaactaaaa agaaagaggc agagcctgca tatgactgcg ggttctgtct ctttcttttt
      361 ctaagaacag agcagacgaa aaaacagcta ggagattaca agctgagccg agtagtcgta
      421 cggccctccc aggatagaca gaagataata attgccggcc tggaactgga cgcggttatt
      481 gataatcggc tctccgcccg ggttggtccg ctgatagacc gttaagaggt agtttccggg
      541 cacaatgtgg agatagcggg tgaaattcat gtagtccaga tcggacacta ccaagcgtcc
      601 gtttaagtaa atatctaatg gctcccggat ggaggcggcg ttgtagaaac ggacatgggc
      661 aatgccggag ggagagacag aagggaagga tccccaggcc cacagcacgt tgcctaataa
      721 gtttgagaga ccgccctgcc cgggtccgca gtttatgcag ccgccggtat ttccgggcag
      781 agagggggtg acggggccgg ccggtccgaa tccgggagct gtgtttggat cagagaccga
      841 gccggatccg gggcggtgat agaccgctga ttcgttttcc gctgttctgg cttcactgcc
      901 tgcctgggcg gatggatcgt aattataggt ttccatattg atacctcgct tccatgatta
      961 tagttcatat atatggcgca ggcctgtcag tttttccaaa attggagact tttcccttga
     1021 aaggactgga aaaaacagat ataatcggtt gtgactataa aaaaagagag ggatttttat
     1081 gaaagagcaa aaaaaggcga gggcgtcggc tcttctgccg atccttgtgt ttctgcttat
     1141 tttcctgggt tccggtttcc tgacaggcga tttttacagc atgccggcca ttgtggcctt
     1201 tttaatcgcg ctgtttgtgg cctttatcca gaacagaagc ctttcctttg ccgataagat
     1261 aaagctggcg gcacagggag tgggcgagga aaatattatc accatgtgtc tgatttttct
     1321 ggctgccgga gcgttttccg gagcggtgaa ggccgccgga ggcgtggaca gcacggttaa
     1381 tctgggcctt tccattctgc cgtccaatgt ggcggtggcc gggctgtttg tgattgcctg
     1441 ctttatttcc atttccatgg gaacctctgt gggaacgatt acagctctgg ctcctattgc
     1501 ggtgggaatc agcgagaaga caggcttttc catggcagtg tgcgccggag ccgtggtagg
     1561 cggcgccatg tttggagata atctctccat gatttccgat acgactatcg cggcggtgaa
     1621 aacccagggc tgcgagatga aggacaagtt cagggagaat tttctgatcg tgcttccggc
     1681 tgccattttg acgatggttt tgttcctggt gctggcaaag gacgcagatt atcagatgga
     1741 gtacgagctg agctacaacg tattcaaggt gcttccgtat ctggttgtgt taatcggagc
     1801 gctggctgga gtgaatgtct ttattattct gctggctgga actgtgctgt ccctgatcgt
     1861 gggcgtggcg acaggagcct ttacagtggc cgagatgttc acccacgtgg gagcgggcat
     1921 taccggaatg tacgatatca ccgttatttc catgatagtt gcctgcattg tggctctggt
     1981 gaaggagtat ggcggcattg aatttgtcct ctcctttatt aagaagcgga tcagcgacga
     2041 gagaggcgga gagcttggca ttgcggctct ttccctggta gtcgatatgt gtacggccaa
     2101 caatacggtg gccattgtca tggcaggccc aattgcgaag gagatcagcg atgaattcgg
     2161 cgtgacgcca cggcgttccg cgtcccttct ggacatgttc agttccatgg gacaggggct
     2221 gattccttat ggcgcccagc ttttagcagc ggccagcctg acgggactga ctccctttga
     2281 gatcattccg tactgcttct atccgatttt aatgggactc agcggactgg tatttatatt
     2341 catgaaaaag agaaaatagg agaatacgat tacgatgaaa gcgcataatc aatgggccag
     2401 caagcttggc tttattctgg ctacggcagg agctgccgta ggactgggaa atctgtggaa
     2461 atttccctat ttaatgggaa gaaacggagg atttttcttc ctgatcgctt atctgatctt
     2521 tatctgcatc ttaggtattc cggttatgat cacggagatg tccctgggaa gaaagacgcg
     2581 ccatgatccg gtgcaggcct atgcggacat ccacccacac gccagagtgg taggtatctt
     2641 cggcgttctg gcggcgttta ttatcctttc ctattacagc gtaatcggag gatggattct
     2701 gaagtatatt gtcagctacg ccactacgtt tgacgctccg gctgatttta acgcctttat
     2761 ttccaacggt gcagagccgg tgctgtggca ttttattttc atgctggcca caacggtgat
     2821 ctgctataag ggagtcagcg gaattgagaa ggtatccaaa tttatgatgc ccatgctgtt
     2881 tgtgcttctt ctgattatca ttggcagaag cgtgacgctt ccgggagcgg gaaagggact
     2941 ggcctttgtg ttcactcccc aggaatccac ctttacgctg ggctccatca ccgcagcgct
     3001 gggacaggta ttctattccc tgagcctctg catgggaatc acgattacct acggaagcta
     3061 cttaaatgat aaggaaaaca ttcccaagag ctgcgccagc gtggcaggcc ttgacacgac
     3121 cgtagcaatt ctggctggaa tcgctatttt cccagctgta ttcgcctttg gactggagcc
     3181 tggacagggg ccgggactga ttttcggaac ccttcccaag gtatttggaa gcattggagg
     3241 aggagcgatc ttcgctctgg cattctttgc ccttgtgttc ttcgcagccg tgaccagcgc
     3301 catcgcgctg ttagaggtat ctgtctcttt tgccatcgac acattgaaat ggaagagaaa
     3361 aagcgccact ctgattatcg gaaccctgat tttccttctg ggtattccaa gcgccttatc
     3421 cttcggcgtg ctgggagacg tggtgatcgc caattacagc gtcttcgact ttgtgggaat
     3481 gattacagat aatattctcc ttccatgcgg cggtcttacc atgtgctact atattggatg
     3541 gaaatggaag ccagaatacc tggtggagga gattgagaaa aatggagtgg gctttaaact
     3601 caaaaagctg tggattctct gcatccgttt ccttactcct gtgctggtag gagttgtcac
     3661 catctcagga ctggtgagcg tatatggcgt ggtctttgct taatcagagc tgaaaagttg
     3721 taagaaaatt gtaaagacta ttccgccgcg gattatggta taataggaac acttggtgag
     3781 gtatttcacg aacctagtgt gagtcatacc tggacactta gtgaggtgtt atacgaactt
     3841 agtgtccacg gtataatata cagcgtcaga aggaaaataa gcgtctgcga agcagacatt
     3901 tattttcacc tgacgctgta tcgacaaaat gagggagctg tcgaagacag cgccggatgc
     3961 gcgaagcgca gccgcatttt ggagagataa cgagcaaaca gcctgcgcag caggcagaaa
     4021 gcgcgaagcg cgggtttgcg agtctgcaaa taagaaagca gacaacacgc agcgcgggtt
     4081 tgcaggtagg ggaaatagta gaaagcttga aacggggcgt cctgctgtcg gcgggacgct
     4141 tattcacgtc ataggagctt gtcctgtgat aaaaacagct gaagcaggag acaggaggat
     4201 ggaatgagac atttaaaatg gatgaaggcg gcggcttcga cggcagtgtt tgcctgcctg
     4261 tttgcaggaa cggtgtttgc ggcggattca gaagaccttt cgtcctgcgt tgtggatgga
     4321 aaccagatta aaattacagg aacagccgtt catacagagg atgaggggca gggagaagcc
     4381 ggccagaaga cggagacggc ggacgacgga aaatattatc tgtttgatct gatgccttac
     4441 gagacgtctc tggaaggcag aagcgactat ttagctgccg cagataagac agagagctta
     4501 tcctttgcgc tgcccttcga caagaaccag aacgaggatc cgctgtttgc cagatatgtg
     4561 gtggcggtga acaggggagg cgtttacgag cctgtcagca acgaggccta tgtgacgaac
     4621 ccggaagtca cctctgatta ccaggagccg tttccggagg ctcagacgaa gaaggggtta
     4681 aatatcgagc tgtccatgct ggacgacgcc atgtcccttg gcgtgaagca cacggccatc
     4741 aacatttctg tcagggagtt tctggatccc aatggagcct taacttacga ttataatgga
     4801 aagacatacc gttttaataa gagccgcgtg gaggagtacg ataagaccat ccgcatgttt
     4861 tccaataagg gaatcattat tacgggaatt attctaaacg gatggaatac ctcccatccg
     4921 gagcttctct accctggagt gaaggagacg ggaacctccc agtattatat gtttaatacc
     4981 tccactcccg agggctttga gacctgccgt gcagtgatgg catttctggc agagcggtac
     5041 aatggaagcg atcctaacta cggccaggtg tccaactgga ttatcggaaa tgagatcaat
     5101 aatcaggaga tctggaacta tacaggcccc atgccgctgg aggagtatgt ggctgtgtat
     5161 gagagaatgt tccgcgtgat gtacgccgcc atccgcagcg agaatgcaaa cgccagagtc
     5221 tacttctcca ccgattacaa ctgggtgcag gagaacaaaa ccctcagcta cggagccaga
     5281 gatttaattg actgcttcag cagccagatt aagaagggcg gacagattga ctggaacctg
     5341 gcctaccatc cttacccggt taaccttcag gagccggagt tctggctgga aaatgaaaag
     5401 gtaacggaca gcgtggactc taaggtggta aactttaaga atcttcatgt tctgacagat
     5461 tacttccagc ggccggagct tttaaacagc gcaggccagg tgcgccacat tatcctgtca
     5521 gagcagggct ttacttccca gagtcctgcc aggggaaatg tggagaaaga gcaggcggca
     5581 gcctttgcct acgcgtattt cctggtagac agcaatccgt acatcgactc ctttatttta
     5641 agccgccagg tagataatcc ccacgaggcg tctctgagca tggcgtttgg cctgtggacg
     5701 gcaaatccca attccccggc caatgcggcg cctgttggtt ttgacagaaa aaggatctac
     5761 ccgattttca agattataga ttccagaaaa gcggtggagg agacagagga cttaaaggca
     5821 gtcatcggaa tcaacaagtg gagcgatgtg gttccgaact tccgatgggg aacgaacaac
     5881 taaaagaaag gccggaaaga aaatttcctt gttccaactg gaagctgccg gaaaatttct
     5941 tttctgctgt gagagccgta tccctgccgg ctcaagcttt tgctcctcca gcttctgcct
     6001 cggttgacaa atcgaaaaaa tgggcttata attcctgaga attgcgacat catgggattt
     6061 ttcataaggg gattcacata aaagcttatt aggaggaaag ggaacaatgg cagcaccaag
     6121 aaagagaacc gcagctaaga cagcggcaaa ggaaggaaag gatcaggctg tatctgcagc
     6181 agagactgtt ttagaggcag cggagtctgg gaagacagag gctaagaagc tggcagccaa
     6241 gagaagcact gccagaaaga cagctgctaa aaaagaggta aaggcgcagg tgttcgtcca
     6301 gtatctgggc aaggaaatct ccgctgacag ccttgtggag gaggctaaga aggcctttgt
     6361 ggcagcagga cacaaggaaa gcgagatcga gaccatcagc gtgtatgtaa agccagagga
     6421 gaacgccgct tattatgcag taaacggcgc aggctctgag gagtacagaa tccagttata
     6481 aaagctgaga agatcgtggc cggaaaaggt acgtcggggc agaagagctt caggcgtgcc
     6541 ttttttatat gatttttttc aaaacagggc gggagaaaaa cagccttaag cggtttgcgc
     6601 agacgcagca gacaaaggta tagaaaatct ccatggcgct gttgacaatc cctgtgatca
     6661 ggtaggaagc tgcgcagaag gcggcgttta agatgagaag gcacaggagc gctcttcctt
     6721 cccgcctgga cgaggcatga aaatagactg gcagaacaga cagagccagc aggataaaaa
     6781 agcttacgga ggaccagacg caggtataga cgtggacctg tgaccagaaa ggttcctctt
     6841 caggcagata aggagtgaaa acagctgtca gaaggagaac ggcagggaag aggaagaaga
     6901 aaactacagg gaagggctgc tttttccgaa agaaaccgtt cgctcccgga cggcggccct
     6961 gatcctgaag gcggcagcac agagggagga tgcacagaaa taagtacacc agaagagaaa
     7021 gactccacag aaggaattct ccctgcctgt ggctggcagt ccggatggaa gaaaaattgg
     7081 tggcgaacag atccgtctct ctggcaaggg cagccgccag aaacgggatg gcaaaataac
     7141 cgaaaaaatc aaaaaacata gaaaaaatcc tcctcgcagg gattagtatt tcccaagacg
     7201 ccgcaggtat gttagaataa gatttgaaaa aatgaaaaat aaaggtttac tgaaacagaa
     7261 caaagcgagg aaaacatgat ggaactgccg caggcattta aagaaaaaat ggaacgcctt
     7321 ttaggcgcgg aatatacaga gtttttggaa agctacgaga aggagagaaa gcagggactc
     7381 agactgaacc ttctgaaaac cagccggaag aagtttgaac aggaagcgcc tttttccctg
     7441 tctccgattc catggacaga ggagggttat tattatggaa aagaggatcg cccgggcctt
     7501 catccctacc atgaggcagg ggtgtactat atccaggagc ccagcgccat ggcggtggtg
     7561 tctctcttag atccgaagcc gggagagcgg attctggatc tgtgcgcggc tccgggaggg
     7621 aagacgagcc atatcgcgtc caggctccag ggccgcggat ttctggcggc caatgagatt
     7681 cacccggcca gggcgaaaat cctgtcccag aacgtggagc ggatgggaat cgggaactgc
     7741 gctgtattta atgagacgcc ggaccgcctt cttcgtcatt tcccggagta ttttgacagg
     7801 attgtgacgg acgcgccctg ctctggagag ggaatgttca gaaaggatga ggcggccaga
     7861 ggagagtgga gtccggacaa cgtcaagctc tgcgcagaga ggcaggccta tattttagac
     7921 tgcgcggccg gaatgctgaa gccgggagga accatagcgt actcgacctg taccttttct
     7981 ccggaggagg acgagcaggc agtggaggcc tttttggacc gccatccgga atttcatatc
     8041 aaagaagtga aaaagccgga gggcctgtca ggcggcgtac ctcagtgggg agccaaagag
     8101 cggccggagc tggcgcgcgc agtacggatt tggccccaca aaacaggggg agaagggcat
     8161 tttattgcca ttttggagaa ggaaaaggca gagggctggg aggacggcag aaagagaacg
     8221 tatccggctt actggaaaga cagaaaagct ctgagagatt atgagagctt cttaaaggag
     8281 accatagcgg atttggggga ggattctgcg ctttcccgcc tgttagacgg cagggagctt
     8341 accttaaacg gagaacagct gtatcttctg cctcctgagc ttctttcctt tgacgggctg
     8401 aaggtgctta ggcctgggct tcacctggga accatgaaaa agaacaggtt tgagccttcc
     8461 cacgccctgg ctctctggct gggagagaag gacgccctgc gtttctgccg catgaatccg
     8521 gacagcccca gactggccgc ttacctgaaa ggagaggcag tcagcctttc ccagctggca
     8581 gaggaggaga gcgtgcaggg cgccggaccg gccgataaag ggtggacgtt tgttacggtg
     8641 gcgggaaacg gcagcggata tcctatcggc tgggccaagc tggccggaca gacactgaaa
     8701 aaccattatc ccaaggggct cagacgctaa aaaagcaata aaatatttga cttttgggat
     8761 aatacatatt aaactagaat ttatggctga cgaaaagcct tgagagacag ctttaccagt
     8821 taaggaggaa atgttttgag cgatataaat aagacaaacg gcagcgcaga gaccccggag
     8881 acagagaaga agcctgccga gaagaaaaca gcagcgaaaa agacttccga gaagaaggcg
     8941 gctgagaaaa agacaaccac aaagaagacg gctgagaaaa agactgcctc aaggaaaacg
     9001 gcagaaaaga ctgctcctaa aaaggccgct gagaagcagc cggagaagaa gaaagtgaac
     9061 gagaagctta tcgaggctct ttcccagtgg gagaagaatc cgtccagaga gaatctgaac
     9121 gctgtgatgg aagaagtcgt tatgactgga aaattcctgg ttcctgcagt gacggcagag
     9181 ctgacagagg aggagagccg caaggttgga tctggaaaag gcaagaagat gcgttttacc
     9241 acatttacca atgccaaggg acagaaatat ttcccggcgt ttacttcacc ggcccagctg
     9301 cttctctggg ataaggagta taaaggcgag acggcggttc tgacgttcga cgatctgtgc
     9361 tccgtagtag gctggaatcc agatatgctc ggatttgtag tagatccgtt cggcgctaat
     9421 ctgtctatcg gaggagagct ctgcggccag ttaaagcgca aaaaagacct gctcagaaag
     9481 cagtatgcag agcttgtaag aaaaaatctg aaacgctaag agaaacattc agatatgatg
     9541 aaaagaaaag gagacgcgct ccgggcttcc agttgtgaaa gccggagcgg tctcctttct
     9601 tttttgcagg aaaaaatttc tgcgaaagat gtgtttttcc ggcctgcagt tttacgcctg
     9661 cctgtccgga cggccagaag gcgccggaca gccggaaaca gaacatccat ccggtacggc
     9721 gaaggaaaag tcgtctggaa tccgggcctc aaaggtcatc tcctttccag tcagaggatg
     9781 agagaaggag agccggaagg agtgaaggga ctgtctgcct ataaagcggt agtcaggatg
     9841 gtagagaaaa tctccgtaga gagggtggcc gatgtgcttc atatgcaccc ggatctggtg
     9901 ggttcgtccc gtctcaaggg agagaaggat cagggaacag tccttttccg gacagtagta
     9961 cagcctttga tagtgggtac aggcgtattc cccccgttcc tcgtccacac accgctcgat
    10021 ggtagagccg tccgcccggg caataggagc gcagacagag ccggactcct ctgtttttcc
    10081 ggacacagcg gccagatact ggcggcggat ctgctttttt gccaccattt ctgagagaag
    10141 cgcagcgctc agcaggtgct tggcaatgat cagaaggccg gttgtgtcac gatccagacg
    10201 gttgacggcc cggaaggtga agctctctcc cttctgggca aaataacagg cgactccatt
    10261 ggccagagta ttgtaaaagt ttccctggga ggggtggacc ggcataccgg ccggtttgtc
    10321 aatcaccatc aaatcctcgt cctcatagag aatggtaaat tcctgcttca caggcacgat
    10381 gtgtccggat ggggaatcgt cgggaacacg gatggtgaga agatctcctt cagataaaat
    10441 ttttgtagta tacacagggg tttctccccc ggctcccaga cagattccgt gatccgtttt
    10501 tctgagacgg acgagaagac gccgggagaa cccgcgcagg cgcagaaact gttcaatggt
    10561 cctgccctgg tcctgttctg taatttgata agtaaatgtc tgtttcatga cactgattgt
    10621 atcacagggg cggcaggctg gcaagggcag gaagctccgg ctgtctgttt ctgaataggg
    10681 cagtttctgt ctgcatatag ttttaataag ctggcaggaa aggaatgcag tgagagattg
    10741 aaacaggaaa gcagacgaaa aggagcgaaa agccgggaga tgaaaggcgc gcttttggga
    10801 atcggcctgg ccgctctggc cgtatccctt ccgggaatgg aagcggagaa aacggctgca
    10861 aatctaaaac agcccctttg cagcagcctg gcagagcttc cgaaaggcac aggggaggag
    10921 aaagaacagc cttccttttc ccttcacgcc cagtcggcag ttctgatgga cgcagagacg
    10981 gggagaattc tgtatgaaaa ggatggggag acgagacggc ccatggccag caccacaaag
    11041 attatgacct gtattctggc cctggaggag ggaaatccgg aggatctggt ggaggtttcc
    11101 gcctgcgcgg cgtctatgcc ggacgtgcag ctggggatca gggagggaga gaagtattat
    11161 ctgaaggatt tgctgtattc cctgatgctg gaatcccata acgattccgc ggaggcggta
    11221 gcagagcaca tcggcggttc ggcagaggga tttgcggatt tgatgaatca gaaggccagg
    11281 gatattggct gcgaggatac ctgctttgtg acgcctaacg ggctggataa ggcgagagag
    11341 tccgatcaga cgccccactc caccacagcg gaggatctgg cccggatcat gcggtactgc
    11401 attcagactt cccccaaaaa ggaggaattt ctggagctga cgagaacggc ttcccactcg
    11461 ttttcagacg aatcgaggaa acgctccttt tactgcggaa atcataatgc atttctaaat
    11521 atgatgccgg aagctctgac agggaaaaca ggatttacag gagcggccgg ctactgctac
    11581 ataggagctg tgagaaaagg ggagaaaacg ttcatcgccg ctctcctagg gtgcggctgg
    11641 ccgccccata aaacatggaa atgggaggat atgaaacgcc tttccagcta cgccttaaag
    11701 gaatatgagt atcaggaaat ctatgacagc gcaaagacgt ttccgaaggc ccgggtggag
    11761 aacggagtaa gagacgcggt tcccctggaa atcaggggga acggcagaaa ttccctgcgg
    11821 gtactgatga gggagggaga gagaccggat gtgcggtatg aatatccgga gaagctgtcc
    11881 gcgccggtga aacaggggga tccggtggga agagccgatt actatctggg agaaaccctg
    11941 ctttccagct atccgatttg cgccgcagag ctggtggaga agcggacaat ctggctctgc
    12001 ctgaaaacgt gcctgtccag gtggatgaac gtcccggaaa cttccataaa aatctttcat
    12061 ttcttttaag tttcagtaaa acgctttatt taatcagaat attttgatat aactaaagat
    12121 agcaaatgag agcaaggagg acaatggcat ggatgcggga atcagcagag ctgaggcggc
    12181 tgaactttta aagaaatata ataaagaacc cttccatatc cttcacgggc tgaccgtgga
    12241 gggcgtgatg cgctggtatg cagaggagct tggctacggc ggagagaagg atttctgggg
    12301 ccttgtgggg cttctccacg atattgattt tgaattgtac ccggaggagc actgcctgaa
    12361 agcgccggag cttctgcggg aggccgggat ctctgaagaa ctgattcacg gcgtagtgtc
    12421 ccatggatat ggccacagag tggaggtaaa gccggagcat gagatggaga aggtgcttta
    12481 tgcggcagat gagctgacag ggctcatctg ggccgctgct aagatgcggc cgtcaaagag
    12541 cgctaaggat atggagcttt ccagcctgaa aaagaaattt aaggacaaaa aatttgcggc
    12601 cggctgctcc agggacgtga tccgggccgg agccgatctg cttggctggg atctggacca
    12661 gcttctggag aagacgattc tggccatgag ggcctgcgag gacgaagtgg gcagacagat
    12721 ggaagcatac aacgcataga aggaggacat acttttgaaa cttctgacga ttgccatacc
    12781 gtgttacaat tccgccgcct atatggagcg gtgcatcgaa tccctgcttc ccggcgggga
    12841 ggaagtggaa attttgattg tagacgacgg ttcgcaaaaa gacaatacag cggagattgc
    12901 agatcagtat gagaagaact atccgggcat ctgccgcgcg atccaccagg aaaacggagg
    12961 ccatggggaa gcggttaaca caggactcag aaacgctcag ggcattttct ttaaggtagt
    13021 ggacagcgat gactgggtga atggggaggc ctaccgggag gtgcttaaca cgctgcgccg
    13081 gtttgcacat gaaaatcaga ggctggacat gcttctgacc aactttgtct atgagaagca
    13141 gggagctaag cgcaaggcgg tgatgaacta cagaacggct attcccaagg acgagctgat
    13201 cgactggagc agcgtccgca tgtttatgct gggacagtat attctgatgc actccgtggt
    13261 gtacaggacg gagcttctcc gcggctgcgg cctggagctt cccaagcata ccttctatgt
    13321 ggacaatatt ttcgtgtacc agcctcttcc gcacgtaaaa tccatgtact atctggacgt
    13381 gaacttttac cgctatttta ttggaagaga cgatcagtct gtcaatgaga cggtgatgat
    13441 tggccggatt gatcagcaga tccgggtgac gaagctgatg ttagggtatt acgatgtgat
    13501 gaagattccc aaccgcaagc tgcgccgcta catgatccgc tatctggaga ttatgatgac
    13561 tgtttcctcc attctggcta tccgttcaga gacagaggaa aatctggcga agaaaaagaa
    13621 gctgtggcag tatttaaaga agcagaacct tccgctctat atccgcctgc gctggggatt
    13681 tttgggacag ggagtcaatc tgccgggaaa gagcggcaga aaggtgtcca ttgcctgcta
    13741 taaaatctcg cagaaattct acggatttaa ttaaaacgga ggttacagat taataggata
    13801 taaaaaagac tgccgggtat ctgacgtttt atcagatatc cggcagctgc cgtttaaaga
    13861 ctgttatgta attaatttta tggagctttc tctggacagc taccgtatta aaacgccttc
    13921 ctgatcgttt tcgcgggacc tctgagcgcc cggggcgtag accagcgggt aaacggctcc
    13981 gcataacagg agagcgccgg ccacgtcaat aatggagtgc tgctttaaaa atacagtaga
    14041 catacagata gaaaccataa ggacgccgga aatcaggcgc acgatccggt tgttcttaaa
    14101 ctgttcgctt cggatgattc cgatatgcac ggccacagag ttataaacat gaatgcttgg
    14161 gaacacgttg gtgcaggtgt ccgtggcgta cagaagagag acggcctttg caaatatgtt
    14221 tttttccggg tcaacgtaag gcctgaaatc agtgccgttt ggaaaaagag tgcagattaa
    14281 aagacttaaa gtcatccctg taaacagaag aatacagaca cggtaatagt cttccttgtt
    14341 tgtaaaaaag aaccagagga tcacagccgc aatgtatgcg aaccagagaa aataggggat
    14401 gataaaatat tcgttaaagg gaatccagtc atccaccacg ctgtgcatta catgatagcg
    14461 ggtcgtcaca tgcttttcca gatagagaaa ccatggaaga tagatggcaa agtaggccat
    14521 aatccagatg tggccgtatt ttttgattag tttttttaat gaactcatat tcatcactcc
    14581 tcaataagga tacagaatca tattaacacg attttaataa ctttgggaga ttatagcaca
    14641 ttccggaagg gggttcaagg gagtttagaa aaggttaata aaaatgtaag tcccagctgg
    14701 ataagggaca ggcccggaga cagaaaggct tttagaaaaa aataaaaccc ttgaaaaatc
    14761 aagggtttct aaagtagcgg aagggagatt cgaactctca tggtcgctct caaatacata
    14821 nnnnnnnnnn tttttgcaat atctagtggg ttagatgaaa aatctgtcaa gaatttgtgg
    14881 ttacaaacga aagcctgttc ttgacagatt ttttgtatgg ttgagaataa ctcataatac
    14941 taaaacgagg ttgatagacg cttgtgtcca tcaacctctt gagtactact tagtatcgta
    15001 tttgcatgtt aagactcata tcttttaaaa actgtttttt ccatcaattc ttttccagcc
    15061 agttcattca ttggatgccc ttcatttatt aattttccag tgtatttgtt gataagagaa
    15121 aatgcatcct gttcgaatcc aatgataccc cattttacag cttcttcata aatagtaatc
    15181 tctttcgtat ctatatttcg atttcctata cgaatccatt catttccttg taattcatag
    15241 atataatcac catagatgtc atcaatatat tctatagtac cattttcagc gttctttatt
    15301 tcaataaaac aactaaaatc tcctcctact cctaattcat atctttcatc taaaactgca
    15361 tcataacctg tataatctct ctcttcatgc actggtgttt cagcataaag ctcatatgac
    15421 tgtgtcgctt cattctttac atagagttgt gttttgtaat atgcatattt ccctgccata
    15481 ttctgagtgg gttcgttatc gttcataacc tttttgcttt gaattgttcc attttccacc
    15541 catgccccgt ctgcatttac gctataccca tccggcgtgg tagtattagt caacagccat
    15601 ccattattat caaaataata gcactctgct gttccgtcat tattgccatc aatccactgc
    15661 cagccgttgc tggtatagga accattgcca ttgtcatacc accattttcc ttgattttct
    15721 ccagttcccg tctgccatgt tccagcaaat acagttgatg acatgagcag tgagcaaatt
    15781 gcagttgcga cagttactaa tttctttcgt ttcataaaaa aatacctcca ttcagtaatt
    15841 aggaaataac aaagatttcc attgataagc ataacacatt ctaacgatat acgcaactgc
    15901 gtacacgcga aagcgtataa aaatgtatcc tttcttcaaa taacattgag aaggagcatt
    15961 aaaatgaatg taaagcaggc tgtagcaaga agaattgaat tgctttgtaa ggaaaggagc
    16021 attgcataca atgaattggc taatttatgt ggtattactc catctaccat ttattctatt
    16081 tttgatgata aaagaaaaaa tattacgcta tcaactgtta agaaaatatg tgatggtttt
    16141 gaaatcagct taggagaatt tttctcacat ccactttttg ataccttaga acaggaaata
    16201 cgctaatatt tactaaataa tttataattt tttaacaatc tacatattga catttcttta
    16261 aaaaaaagat acaatatata gtatattgga atgttttcca gatgagataa cattttatac
    16321 gcacactatt tagatgttcg aaaaaaggat taaatttgtg taccatgcag gctaagcgtt
    16381 tgttcataag gaaaggagat acaataggcc tgtaaattct acgccaaaaa atttttgatt
    16441 tggattgagc agaattcgat agtgcattag ggaaccatac cataatggtt cgtgataggg
    16501 attgtgggtt gtttgtcaac ttgcctatta ctctaattgc ac
//
LOCUS       DBMDUW010000056        15537 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_2110_length_15537_cov_2.948627, whole genome shotgun sequence.
ACCESSION   DBMDUW010000056 DBMDUW010000000
VERSION     DBMDUW010000056.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 15537)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 15537)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15537
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2110_length_15537_cov_2.948627"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..375
                     /locus_tag="ACZPCR_09810"
     CDS             <1..375
                     /locus_tag="ACZPCR_09810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1231207.1"
                     /translation="YNTIWATLFATINGIMTIDKVYLDKANTLELNPAESLFKVIMPA
                     AMPSIMSGFITSLRGSFVVLVYAEMYGAKYGMGFYVKKYAEYGMYDRAWSGFIFMVVV
                     LVIVMQIFERMKNHMLRWTLNN"
     gene            405..1589
                     /locus_tag="ACZPCR_09815"
     CDS             405..1589
                     /locus_tag="ACZPCR_09815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005330708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mandelate racemase/muconate lactonizing enzyme
                     family protein"
                     /protein_id="HIR1231208.1"
                     /translation="MKITKVDVILVDVKPEDGNKWSPILCRVYTDEGIFGDGEAAMSY
                     GTGSTGAFGTVSDFAKKIIGMDPLKTELIWETLYKETFWGQNGGPVIFSAISALDVAL
                     WDIKGKYFKAPVYQLIGGKVRDKLRCYASQLQFGWSDKKEAAVTTEDYVRNAKLAVAE
                     GYDAIKIDFFMFGEDGKRFNHELTTRLLPPKYVNLVISRLAAVREAVGPDIDIIMENH
                     SSIDAQAAVQLGRLAEKYNIFCFEEPCTPNPKMNKFVSERLNMPIAQGERIYTRWGYA
                     PYFEDGSIQMIQPDIGNCGGITETKKVCDLAHIYDVGVQIHVCSSPLLTAASLHLESV
                     IPNFTIHEHHVYNRYDYNKKLCKYDYQPSGGYYTCPDLPGIGNEISDWAFENASIKTT
                     IK"
     gene            complement(1686..3089)
                     /locus_tag="ACZPCR_09820"
     CDS             complement(1686..3089)
                     /locus_tag="ACZPCR_09820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016281303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HIR1231209.1"
                     /translation="METKRKSSFTGSLGFVLAAAGSAVGVGNIWRFPYLAAKDGGGLF
                     LLIYLALVLTFGFTLLVTDVAIGRRTKTNALHAFGSMNKKWTFLGYVTFLVPAIIMTY
                     YSVIGGWILKYLAVYLTGSGTETAGDGYFTGFITSPVSPIFFMLVFLAFTAFIVYRGV
                     EKGIEKFARIVMPGLLLMIIGIGLFSLTLKYKGDDGIIRTGLQGMAVYLIPNFDGITP
                     ARFLEILLDAMSQLFFSLSVSMGIMITYGSYVYKEVNLNRSLGHIELFDTGVAFLAGM
                     MIIPAVYVFFGTEGMASGPSLMFVSLPKVFEAMGPVGQVLGMVFFLMVVFAALTSSVS
                     IMETLAANCMDIFHSTRKKTSLAICLIFAAASVVICLGYNVFYFELTLPNGATAQLLD
                     LMDYISNSFLMPFISLLTCIFVGWIVGPKWICEEMEASGHPFSRKKMYVFMIKYVTPV
                     IMAVLFLQSAGVFNMFS"
     gene            3309..4037
                     /locus_tag="ACZPCR_09825"
     CDS             3309..4037
                     /locus_tag="ACZPCR_09825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007864750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1231210.1"
                     /translation="MGNINLHAGMKIRMYRKNKNMTLQQLADRIHKSRASVSKYETGE
                     VSMDIETLVEIAAALDVSPGRILDFPAEEEQTEPVRPAPAGMSPFFRASRLYFYFYDG
                     RYKRLKDGIINIREAEEQPGSYEADLSISTVNPSGRSSEVYYTGKVVYSDMLIRFSFV
                     NQYNSLEEDLLYIFNPLDLRDSTEGLLCGISSADLMPCAFKCLVTLTPQEHTEEFKKR
                     LLITREELSRWQKLNMLLVNNLDY"
     gene            complement(4034..4789)
                     /locus_tag="ACZPCR_09830"
     CDS             complement(4034..4789)
                     /locus_tag="ACZPCR_09830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1231211.1"
                     /translation="MENYLSIGEVSRLLNIPEHTLRYWQDAGIFSVRQEMNNYRKYTM
                     ADLLNIAEVAFYRNIGIPVKQMERFNRFGLEDYSQILDDVKLRVERQMEELRAMHQLI
                     LLKEQHLQEISVLRQRDYSWEDVPFRSVVRFSYSDQDKLTEYTRNPSLYVRCIDTADL
                     SQEVRGIICESPALQDEILWQAKRPQTSRFASFLIEEYPEEGYSNNILEKLEPIRKQA
                     DTGILLANFLMSEVKDGRKVDYLKGYVEVLEPF"
     gene            4938..6347
                     /locus_tag="ACZPCR_09835"
     CDS             4938..6347
                     /locus_tag="ACZPCR_09835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HIR1231212.1"
                     /translation="MSEKTKRKKWFENVKMPHTYVILITILVIMTILTHIIPAGQYQR
                     VEDPVSGTTVVVPDSFEFVDVDAPGFFDIFLSLQRGYVDAADIMFLIIFAYGFVFMLV
                     KNGTMDAALGTLVRLVGKKIQLMIPITMIVLGLLSSTMGIFEEVYGLFPVFVGIAVAL
                     GYDMVVGGAIVYLGVTIGYASGTFNPYTIGIAQDVAGVPLYSGLGLRIAVLIAFELLA
                     ILYIMHYARKVKADPTKSVMYGVETDFVQRKSLEELTGSKMDTRQKISLVLFLGTLGG
                     LLWGITQAGWGINEIAAMFLMMMIFVGIVSGYSATDICKTFIESTKSMVSSMLIVGFT
                     RGILLVMKDGMISDTIVYYLVSLLSEASKFVSAYGMLFLQNIIKFFITGSSSQATITM
                     PIMAPTAELIGLSKQIAVLAYQFGNGFAEMFWPTSCALGCGLMGVPINKWYKFITPLF
                     GMVLVLEVVFMTIAVAIGY"
     gene            6368..7507
                     /locus_tag="ACZPCR_09840"
     CDS             6368..7507
                     /locus_tag="ACZPCR_09840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HIR1231213.1"
                     /translation="MLIKNGKVLLFEENGFVKRDLRVKDGKIQEIGEGLSPEQGEELL
                     DAEGKYVTPGLIDAHSHICVSEEGMGAIGDDCNDYSDALMPYLDTLDAINPFDLAVKS
                     AVEAGVTAACTCPGSDSVIGGMCSVISLTGTVAEDMLLKGKAAVKCSFGENPKNAGYG
                     FKSRMGNAWLLRKCIEDALEYRHHKEEAEKSGSYFRTDIGMENMLPLLNREIPLHAHV
                     HRADDICTAIRIAREYNLRLVLVHCTDGVSVLDYLKQFDYPVILGPTINPRSKLECMA
                     KRFETAGIMSRAGIKVCLTADHDVTPIYYLPVYGAQAVKAGLDEVEGLKALTRNPAEV
                     LGIGGRKGEIKEGKDADLVIWSGRPFDSCTKAETVFIMGKKEAGN"
     gene            7660..9051
                     /locus_tag="ACZPCR_09845"
     CDS             7660..9051
                     /locus_tag="ACZPCR_09845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HIR1231214.1"
                     /translation="MGTLKQRMQSMKMPHTYVILTGILLLVVALTYLIPAGEYARVLD
                     PVSGREIVDPDSFHFVEGNRPGFFGIFLALQRGYVDAAGILFLIIFAYGYVYMLIDNG
                     TLNALIGGLIRALGEKTFLIIPVGMAVFGILGSTMGIFEEVYGMVPVFAGIAAALGYD
                     IIVGGAIVFVGVATGFAAATLNPFSIGIAQSIAGVPMFSGLLFHTAVFITFQTAAVLY
                     VMWYARRVKKNPRHSVLYGEHLEGLPSHELTRDHMTGRQKICLALFLFTIGLLLYGTT
                     RLGWYIDEIAAMFLMMMIATGAAGGYGATKICKTFIESTKSMIASVLVVGFTRGIVLV
                     MKDAMITDTIVYGLSHLLNGQGPVVSSVGMLAMQNVINFFITGSSSQAAITMPIMTPV
                     ADLVGVSRQTAVLAYMFGDGFSDMFWPTACALQCGLMGIPLGKWYKFMTPLFGIMVVL
                     QTVFIILSVYVYV"
     gene            complement(9099..9998)
                     /locus_tag="ACZPCR_09850"
     CDS             complement(9099..9998)
                     /locus_tag="ACZPCR_09850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HIR1231215.1"
                     /translation="MIYTICNSALTACIDETGAQLISLKDKNGTEYIWQRDPAVWSSC
                     SPLLFPIIGNLRNGKTVIDGKTYEIPKHGPVRSLSFHLKEQGNEFVTLGVTDQDFPEG
                     VYPYAFSFSITYSLSGESLSFSVKIENPAASPMAYCVGLHPAVCCPLFPGERFEDYEI
                     RFPRPQQSGYRAFDLEHMQFDMTTERPCPGGGLHIPLNRELFCSDAMWFDRPSSREAS
                     LVHLKTGKGVRAEFPDFETIAFWTKPEDEARYLCFEPWNGSAPCSGEDDDFFHKNHLQ
                     KLSGGASRTYRLRLTVLHENPYV"
     gene            10161..10391
                     /locus_tag="ACZPCR_09855"
     CDS             10161..10391
                     /locus_tag="ACZPCR_09855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231216.1"
                     /translation="MNPMDMIKIAGMWSAFKQRHPKLPMFFRKAAETGAFRPETVLEL
                     TVKTPDGREMAANMKIMAEDLELLEQLVSMKQ"
     gene            10812..11438
                     /locus_tag="ACZPCR_09860"
     CDS             10812..11438
                     /locus_tag="ACZPCR_09860"
                     /inference="COORDINATES: protein motif:HMM:NF012798.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HIR1231217.1"
                     /translation="MAVNSFLSFCGLGELKVKAYKFQRPLVADPARELNRDEYLRLLE
                     TAERMGKYRLYLILQTLCSTGIRISELSCITREAVQTGRCVVRLKGKSRIVIIPQKLR
                     ERLDAYCKEENIQSGQVFLSRKGQPLDRSNIWGEMKRLCRTAEVDERKVFPHNLRHLF
                     ARTYYKKNHDIVYLADILGHSSVDTTRIYTSISIKEHEKVLEDMELTF"
     gene            11686..13131
                     /locus_tag="ACZPCR_09865"
     CDS             11686..13131
                     /locus_tag="ACZPCR_09865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015519930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HIR1231218.1"
                     /translation="MKRLIAFFGSLGLMLASSPLTALAAGTGSAGETGSVPLWMCVPF
                     AGLLLCIAVLPLVKGEWWESHQPHAVLFWSLLFAVPFAVKFGAGTASETILECLINDY
                     LTFIVLLFGLFCVSGNITMSGDLAGSPRVNVGLLALGTLLSSWIGTTGASMLMIRPVI
                     KMNSWRKRKRHIIIFFIFLVSNIGGCLTPIGDPPLLMGFMRGVPFFWSLHLLPILLVN
                     MAVLLAIFYFIDLRAYRKDIAIGLKPDISKPGTEVKLRGTHNLIFLAAIVGAVILSGT
                     LPGLPAFQDAAGNVKGIHIFGEVVLSYPAIIEIVIILISAFLSFKTTESEIRRENHFT
                     WGAIQEVAVLFIGIFITMQPALMLLKANGANLGITEPFEMFWATGLLSSFLDNTPTYL
                     VFLTTAGAVGFTEGLTTALGVIPIQMLTAISCGAVFMGANTYIGNAPNFMVKSIADEN
                     GVRMPSFFGYLLWSLVILVPVFALDMLLFFL"
     gene            13146..14213
                     /locus_tag="ACZPCR_09870"
     CDS             13146..14213
                     /locus_tag="ACZPCR_09870"
                     /EC_number="2.7.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005422447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0050145 - nucleoside monophosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidylate kinase-like family protein"
                     /protein_id="HIR1231219.1"
                     /translation="MSGNTSNETKIRALAERIYDLDAQVYASLGSSLGRVFNRDRERC
                     VRELVSLMMTRPEGNLVRSEIALIGNMARTIQDKEERRLVMTEYNDILQEVMELPTSF
                     ASGDVVNLELAKLNTFNLKNRFTDKDHLIICIGWTYGSGGVNIGFKLADKLKINFYDA
                     EIFEAVLKRLEAEKDSVEDKGGYKIESPGEKLQNPSDAFKPERHLTLRQHMRKFSRFH
                     GLPKEDAVFFNESDLLCDMAKKEDFVVLGRCSDVIMTNNHVPHVSIYITAPFEQRIKR
                     AMEIDSTMTVKQAVRYLKHLDRERSKHYRFYTGRQWGNANNYDLCINSASYGIDGTVD
                     FIYNMINLRLEESRKEAGASQ"
     gene            14324..15097
                     /locus_tag="ACZPCR_09875"
     CDS             14324..15097
                     /locus_tag="ACZPCR_09875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009250375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HIR1231220.1"
                     /translation="MYQISNFTDNDDVKILAEMGAFQVIEYQRDLSVSPSSAITAYFS
                     SEMNVRKRQLVCYLDKSHVTIQAGAMQWMLGNVNATTGVKGVGDFFGKAVRGKASGES
                     AIKPEYTGDGVLVLEPTYKHLILMDTASWGGGVVLDDGLFLACESSLKHKAVMRSNFS
                     SAVAGGEGLFNLSLNGSGVFCIESECPKEELIEITLQDDVLKVDGNHAIAWSKSLEFT
                     VERSGKTLIGSAASGEGLVNVYRGTGKVLMMPTAKMINI"
     gene            15334..15468
                     /locus_tag="ACZPCR_09880"
     CDS             15334..15468
                     /locus_tag="ACZPCR_09880"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231221.1"
                     /translation="MLEVKQLSKSFEGNYVLKNVSLSIEAGEIYGLIGANVPRYILKV
                     "
BASE COUNT         4236 a         3220 c         4064 g         4017 t
ORIGIN      
        1 tacaatacta tttgggcaac gctgttcgct acaatcaacg gaattatgac gattgataag
       61 gtatatcttg ataaagcaaa cacattggaa ctaaatccgg ctgaaagctt attcaaagta
      121 attatgccgg cggctatgcc ttccattatg tcgggattta ttacatctct cagaggatcg
      181 ttcgttgtac tcgtttatgc ggaaatgtat ggagcaaaat acggtatggg attttacgta
      241 aaaaaatatg cagagtacgg aatgtatgat agagcgtgga gcggatttat ttttatggtc
      301 gtcgtattag ttatcgttat gcagatattt gaacgaatga aaaaccatat gctcagatgg
      361 actttaaata attagagact atacagagaa caggagtgat aagattgaaa ataacaaaag
      421 tcgacgtaat attagtggat gtaaaaccag aggatgggaa taaatggtcg ccgattcttt
      481 gccgtgttta tacagatgaa gggatttttg gagatggcga agccgcaatg tcttacggaa
      541 ctggttctac aggtgcattt ggaactgttt ccgattttgc caagaaaatt attggcatgg
      601 atccattgaa gacagagctt atctgggaaa ctctttataa agagaccttt tggggacaaa
      661 atggaggccc cgttattttt tccgccattt cagcgctgga tgtggctctg tgggatatca
      721 aaggaaaata ttttaaagcg ccggtttatc agctgattgg aggaaaagta agagataagc
      781 tacgctgtta cgcaagccag cttcagttcg gatggagcga taaaaaagaa gcggcagtta
      841 caacagagga ctatgtaaga aatgcaaaac ttgctgttgc agaaggctac gatgcgatta
      901 aaattgactt ttttatgttt ggagaagatg gaaaacgctt taaccatgaa cttactacca
      961 gacttttacc gcctaagtat gtaaatctgg ttattagcag gctggcggca gtgagggaag
     1021 ccgttggccc ggacatagat attattatgg agaaccactc ttctattgat gctcaggcag
     1081 cggtccaatt aggccgtttg gctgagaagt ataatatttt ctgttttgaa gaaccgtgca
     1141 ctcctaatcc aaagatgaac aagtttgtca gcgagcgatt gaatatgccg attgcccagg
     1201 gagaaagaat ttatacaaga tggggatatg caccgtattt tgaagatgga tcgattcaaa
     1261 tgattcagcc ggatatcgga aactgcggag gaatcactga aactaaaaaa gtatgtgatc
     1321 ttgctcatat ttatgatgtg ggtgtacaga ttcatgtgtg ttcaagtccg cttcttacgg
     1381 cggcatccct gcatttggaa agtgtaatac caaactttac aattcacgaa caccatgtct
     1441 acaatcgcta tgactataat aagaaattgt gcaaatatga ttaccagcct tctggcggat
     1501 attatacatg cccggatttg cctggaattg gaaatgaaat cagtgattgg gcatttgaaa
     1561 acgcatcaat aaagacgaca attaaataaa cagcaaaaat agctaaaact cccgtgaaga
     1621 aaacatgtat gaggtgcttt tttatacggg agttttagca taaatccaga catcagttct
     1681 ccttatcaag agaacatgtt aaacactccg gccgactgaa ggaacagcac ggccatgata
     1741 actggcgtca catatttaat cataaagacg tacatctttt tccgggagaa gggatggccg
     1801 ctggcttcca tttcctcgca gatccacttt ggtcctacaa tccagcctac aaatatgcag
     1861 gtcagcagag agataaacgg catcaggaag ctgttgctga tgtagtccat taaatctaac
     1921 agctgggcag tggctccgtt tggcagggta agctcaaaat agaatacatt gtagcccagg
     1981 cagattacca cagaggcggc ggcaaagatc aggcagattg ccaggcttgt ctttttccgg
     2041 gtagagtgga agatatccat acagttggct gccagtgtct ccataataga tacagatgaa
     2101 gtcagagcag caaataccac catcaggaaa aataccatgc caagaacctg tccgactggt
     2161 cccatagctt cgaatacctt aggcagggat acaaacatca ggctggggcc ggaggccatg
     2221 ccttctgtac cgaaaaatac atatacagcc ggaataatca tcataccggc cagaaaagcc
     2281 acacctgtgt caaaaagctc aatatgtccc agagaccggt tcagatttac ctctttatac
     2341 acgtaggagc cgtaggtaat cataatgccc atggacacgc tgagagagaa aaacagctgg
     2401 ctcatagcat ccagaagaat ctccagaaac ctggcaggtg taattccatc gaagtttgga
     2461 atcaggtaga cagccatacc ctgcagtcca gtccggataa tgccgtcatc tcctttgtat
     2521 ttcaaagtga gagaaaacag gccgataccg atgatcatca ggagcagacc cggcatgaca
     2581 atgcgggcaa acttttcaat gcccttttct actccacggt atacaatgaa agccgtgaaa
     2641 gccagaaata ccagcatgaa gaaaatgggc gatacaggag aggtaatgaa gccggtaaag
     2701 tatccgtctc cagcggtctc ggttccgctg ccagtgagat agactgccag atatttcagg
     2761 atccagccgc cgatcacaga gtaataagtc ataataatgg caggaaccag aaaggttaca
     2821 tatcctaaaa aggtccattt tttattcatg cttccaaagg cgtgaagggc atttgttttc
     2881 gtccggcgtc caatagccac atctgtcacc agaagagtga agccgaaggt gagcaccagg
     2941 gccagataga taagaaggaa cagtcctcct ccgtcctttg ctgccagata ggggaagcgc
     3001 cagatatttc ccacacctac tgcgcttccg gctgctgcca gcacaaagcc aagtgaacct
     3061 gtaaagctgc tttttcgttt cgtttccata atcaagtaca tcctttttca ttagttttcc
     3121 caaggcacta ttatagaaga aaaacaggaa aactcaactt ggacataatt tcatttaaag
     3181 aaactttttc tataaaaaat tgaataaaac tagaaaaata gagaaaaaga agctataatt
     3241 gcttctgatt aaagtgtttt ttgaaaaaag tatatttata tgaaacaaag tgcgaaggag
     3301 gatattttat gggaaatatt aatctgcatg cggggatgaa gattcgaatg taccggaaaa
     3361 ataaaaatat gaccctgcag cagctggcgg atcgcattca caaaagccgg gccagcgtca
     3421 gcaaatacga gacaggtgaa gtgtctatgg atattgaaac cctggtggag attgccgctg
     3481 ctctggatgt cagtccggga cggattctgg atttcccggc agaggaggaa cagacagagc
     3541 cggtaaggcc ggctcctgcg gggatgagtc cgttttttag ggccagcaga ctgtactttt
     3601 atttttatga cggaagatat aagcgtctga aggacggcat tatcaatatc cgggaggcgg
     3661 aggaacaacc aggcagctat gaagcggatc tctccatcag cacggttaat ccatctggcc
     3721 gcagcagtga agtatactat acaggaaagg tggtctacag cgatatgctg atccggtttt
     3781 cttttgtcaa tcagtacaat tccctggaag aagatcttct ctacattttt aatcccctgg
     3841 atctgagaga ttccacagaa ggtctgctct gcggaatctc cagcgccgat ttaatgccct
     3901 gtgcctttaa atgcctggtg acgctgactc cccaggaaca cacagaagaa tttaaaaaga
     3961 ggctgctgat taccagggaa gaactttccc ggtggcagaa gctgaatatg ctgctggtta
     4021 ataatctgga ctattaaaaa ggttccagca cctccacata tcctttcaga taatctacct
     4081 ttcgcccatc ttttacttcg ctcatcaaaa agttggccag caggattcct gtatctgcct
     4141 gctttcgaat tggctccagc ttttccagaa tgttattgga atatccttct tccggatatt
     4201 cctcaattaa gaaagaagcg aagcgggaag tctggggcct tttagcctgc cagaggattt
     4261 catcctgaag agcagggctc tcacagataa ttccacgaac ctcctgagac agatccgcag
     4321 tatcaatgca ccggacatag agagagggat tgcgcgtata ctctgtcagc ttatcctgat
     4381 cgctgtagga gaaacggaca acagagcgga atggaacgtc ttcccaggaa tagtccctct
     4441 gccggagaac gctgatttcc tgaaggtgct gttctttcag gagaatcagc tggtgcatgg
     4501 ctctcagttc ctccatctgt ctttccacac gaagcttcac atcgtcaaga atctggctgt
     4561 aatcctccag gccgaagcgg ttaaaccgtt ccatctgctt caccggaatg ccgatatttc
     4621 tgtaaaatgc aacctctgca atatttaaca gatccgccat tgtgtatttc ctgtagttgt
     4681 tcatctcctg gcggacagag aaaattcctg catcctgcca gtagcggagc gtatgctccg
     4741 ggatatttaa cagacgggaa acctccccga ttgagagata attttccata agcagtctcc
     4801 tcctttgcag tatgacataa ttataacaaa aatcaggcag acttcaaaca gtaaatgctt
     4861 gactctcaag ttacttgaac ctttataatt gatacgaatg ttaaaaatgt gtaaaaatac
     4921 gcaggaggaa tgaaggtatg agtgaaaaaa ccaaacggaa aaaatggttt gagaatgtca
     4981 aaatgcctca cacctatgtg attcttatca caattctggt gatcatgacg attctcaccc
     5041 acattattcc ggcaggacag tatcagagag tggaggatcc ggtcagcggc acaacggtag
     5101 tcgtaccgga cagcttcgag tttgtggatg tggacgcccc gggatttttt gacattttcc
     5161 tgtctcttca gaggggatat gtagacgcgg cggacattat gtttttaatt atctttgcct
     5221 acggatttgt gtttatgctg gtgaagaacg gcacgatgga cgcagctctg ggaacgctgg
     5281 tccggctggt gggaaagaaa atccagctga tgattcccat taccatgatc gtgctgggac
     5341 tgttaagctc caccatggga atttttgagg aggtgtacgg tctcttcccc gtgtttgtgg
     5401 gaattgcggt cgccctcggc tacgatatgg tggtgggagg agccatcgtc tatctgggcg
     5461 ttacgattgg ctacgcgtcc ggtacgttta acccctacac catcggaatt gcccaggacg
     5521 tggcgggcgt gcccctttac tccggtctgg ggcttagaat cgcagtttta atcgcctttg
     5581 agcttctggc gattctctac atcatgcact atgcccgcaa ggtaaaggcg gatccgacga
     5641 aatccgttat gtacggcgtt gagacagact tcgtccagag aaagagtctg gaggagctga
     5701 caggctctaa gatggacacg agacagaaga tcagcctggt tctgttcctg ggaacgctgg
     5761 gcggacttct gtggggcatc acccaggctg gatggggcat caatgagatt gcagccatgt
     5821 tcctgatgat gatgattttt gtgggaattg tcagcggcta ctctgctacg gacatctgca
     5881 aaacgtttat cgagtccaca aagtccatgg tatcctccat gctgatcgta ggatttacga
     5941 gaggtatcct gttagttatg aaggacggaa tgatttctga caccatcgtt tactatctgg
     6001 taagcctgct ctccgaggca agcaagtttg tatctgccta cggaatgctg ttcttacaga
     6061 atatcattaa gttctttatc acaggttcct ccagccaggc gactatcacc atgccgatta
     6121 tggctccgac tgccgagctg atcggactga gcaagcagat cgccgtgctg gcataccagt
     6181 ttggaaacgg ttttgccgag atgttctggc cgacttcctg cgctctggga tgcggactga
     6241 tgggagtgcc gatcaacaag tggtataagt ttattacgcc tctgtttgga atggtgcttg
     6301 tgttagaggt agtgtttatg accatcgcgg tggcgattgg atactaaaga gaaggagatg
     6361 agtcagaatg cttattaaaa acggcaaggt tcttctgttt gaggaaaatg gatttgtgaa
     6421 gcgggatctg cgggtgaagg acggaaaaat tcaggagatc ggcgaaggcc tgtctcctga
     6481 acagggagag gagcttctcg acgcagaggg aaaatatgtg actcccggtc tcattgacgc
     6541 ccacagccac atctgcgtca gcgaggaggg catgggagcc atcggagacg actgcaacga
     6601 ctacagcgac gccctgatgc cctatctgga cacgctggac gccatcaatc cctttgacct
     6661 ggctgtcaag tctgcagtgg aagccggcgt aacggcggcc tgcacctgcc caggaagcga
     6721 cagcgtcatc ggaggcatgt gcagcgtcat cagcctgaca ggaactgtgg cggaagatat
     6781 gcttttaaag ggaaaggcag ccgtgaagtg cagctttgga gaaaacccga agaacgcagg
     6841 ctatggcttc aaatcccgca tgggaaatgc ctggcttctg agaaagtgca ttgaggatgc
     6901 tctggaatac cgccaccaca aggaggaggc ggaaaagtca ggttcctact tccgtactga
     6961 cattggaatg gaaaacatgc ttccgctttt aaacagggaa atccctctcc atgcccacgt
     7021 ccacagagca gacgacatct gtacggcaat caggattgcc agggaatata atctgcgtct
     7081 ggtgctggta cactgcacag acggggtatc cgtactggat tacttaaagc agtttgacta
     7141 tccggtgatt ttaggtccga ccatcaaccc cagatccaag ctggagtgca tggccaagcg
     7201 gtttgagaca gccggcatta tgagccgggc aggaatcaag gtatgtctga ctgcggatca
     7261 cgacgtaacg ccgatttact atcttcctgt atacggcgct caggccgtca aggcaggact
     7321 tgacgaggtg gaaggcctga aggcgctgac caggaatccg gcggaggttc tgggaatcgg
     7381 cggcagaaag ggagagatta aggaaggaaa ggacgcagat cttgtgatct ggtccggccg
     7441 tccctttgac tcctgcacaa aggcagaaac agtctttatt atgggaaaaa aggaagcggg
     7501 aaactaaact gcttttttga cagagacgtg tccacgggcg agctgcgccc tggacacgct
     7561 ttttggcgta cagagattat tgttagttaa gaaatacgat tcagaaacca ggaaacgaaa
     7621 gacaacatca taaggaaaaa acagaatagg agaagtagaa tgggaacact gaaacaacgt
     7681 atgcagagta tgaaaatgcc tcacacctat gtgattctga cgggaatcct tcttctggta
     7741 gtagcgctga cgtatctgat tccggcgggg gagtacgcga gagtgcttga tccggtcagc
     7801 ggcagggaga ttgtggatcc ggattccttt cactttgtag aggggaaccg gccgggattt
     7861 ttcggcattt ttctggcgct gcagaggggg tatgtagatg cggcgggtat tctgttcctg
     7921 attatttttg cttacggata tgtgtatatg ctgattgaca atggaacgct gaacgccctg
     7981 atagggggat taatccgggc gctgggggaa aagacgtttc tcattattcc tgtgggaatg
     8041 gctgtctttg gcattttggg ctctactatg ggaatttttg aggaagttta cggcatggtt
     8101 cccgtgtttg cagggattgc agcggctctg ggatatgata ttatcgtggg gggagccatc
     8161 gtatttgtgg gagtggccac aggctttgca gcggctacct tgaatccctt ttctattgga
     8221 attgcccaga gcatcgcggg agttcccatg ttttcaggcc ttttatttca cactgcagtc
     8281 tttattacct ttcagacagc ggcggttctc tatgtcatgt ggtatgcccg gagagtaaaa
     8341 aagaatccca ggcactccgt cctttacgga gagcatctgg agggcctgcc atcccatgag
     8401 ctgacaagag atcacatgac ggggagacag aaaatctgcc tggcgctctt tttatttacc
     8461 atagggctgc tgctttacgg cacgaccagg ctgggctggt atattgatga gattgcggcc
     8521 atgtttttaa tgatgatgat agccaccgga gcggcaggcg gctacggggc cacgaaaatc
     8581 tgcaaaacct ttattgaatc cacaaagagc atgatcgcct ctgttctggt agtggggttc
     8641 accaggggaa ttgtcctggt catgaaggac gccatgatca cggataccat tgtttacggc
     8701 ctgtcccacc ttctgaacgg ccaggggccg gtggtttcct ctgtgggaat gctggccatg
     8761 cagaatgtga tcaacttttt tattactgga tcctccagcc aggcggctat caccatgccc
     8821 attatgacgc cggtggcaga tctggtgggg gtaagccgcc agacggctgt gctggcctat
     8881 atgttcggag acggattttc agatatgttc tggcccaccg cctgcgccct gcagtgcggc
     8941 cttatgggga ttccgctggg aaaatggtat aagttcatga ctcccctgtt tggaataatg
     9001 gtagttctcc agactgtctt tatcattctt tccgtctatg tttacgttta aaaagctggc
     9061 tggcgcggta aatctcttta tcacgccagc cggctttttt aaacgtatgg attttcatgc
     9121 agaaccgtca ggcggaggcg gtacgtcctg gacgcccctc ctgaaagctt ctgcaggtgg
     9181 ttcttgtgga agaaatcatc gtcctcgccg gagcagggag cggatccgtt ccagggctcg
     9241 aagcagaggt accgggcctc atcttccggc tttgtccaga aggcaatggt ttcaaagtca
     9301 gggaattccg cccggacgcc ttttccagtt tttaagtgga ccagactggc ctctctggag
     9361 gaagggcggt caaaccacat ggcgtcagag cagaacagct ctctgtttag gggaatgtga
     9421 aggccgcctc ccgggcaggg gcgctctgtc gtcatatcaa actgcatatg ttccagatcg
     9481 aaggcccggt atccagactg ctgcggcctt ggaaagcgga tttcgtagtc ctcaaaccgt
     9541 tctcccggaa aaagcggaca gcagacagcc ggatgaagcc ccacacagta ggccataggg
     9601 gaagcggccg gattttctat cttcacggag aaagagagac tttccccgga cagagagtag
     9661 gtgatggaaa aggaaaaggc gtaggggtag acgccttctg gaaagtcctg atccgtgaca
     9721 cccagagtga caaactcgtt tccctgctct tttaaatgga aagaaaggct gcggaccggg
     9781 ccgtgctttg gaatttcgta ggttttccca tcaatcaccg tttttccatt tctcagattt
     9841 ccgataatgg gaaagagaag gggagagcag ctggaccaga cggcaggatc cctctgccag
     9901 atatattcgg ttccgttttt atccttcaga gagatcagct gcgcgcctgt ctcgtcaata
     9961 caggcagtca gagctgaatt gcagatggtg taaatcacag atagtacctc cttaaacaaa
    10021 aaagatgagt taagtatagc gttttttgga gcggatggca agaaaactta gcggaggatg
    10081 attgtgaaga ttgccccttg cgtttgtctt tcaggctgtt ataatgatgc tggaagaact
    10141 gagatcagga ggaaataaaa atgaacccga tggatatgat aaagatagca gggatgtggt
    10201 cggcttttaa acagcgtcat cctaagcttc ctatgttttt cagaaaagcg gctgagacag
    10261 gcgcttttag accggaaacg gtgctggaac ttactgttaa gacaccggat ggccgcgaga
    10321 tggctgccaa catgaaaatt atggcggagg atctggagct gctggagcag ctggtttcga
    10381 tgaaacaata aaaggataca gacagaaaca ggaaaaggta cagcggacag agaaaatttc
    10441 tctttctgct gtatttttta tacaaaaatt tgattctagc tttgcctgaa agagttggga
    10501 aaatctattt gcaaaaggaa tttcgtgtta tccgatataa ggtaatatat gcaggtaaca
    10561 gaatggaatc ccaaatgtga ggagaaagat ggatgaaaag aatgaagatg acagaaaaaa
    10621 agatggaagc attcaaatgc tggctggtgg aagaagaaaa aagcagggcc acagtggaaa
    10681 agtacaggcg tgacattaga aaattttatg agtttttgcc agaagacaag gaaattaaca
    10741 gggaaagagt gctgttgtac aaatcatctc tgctgccgcg ttatcaggta agcagcgcca
    10801 attctatatt gatggcagta aacagttttt taagcttttg cggccttgga gaactgaagg
    10861 taaaggcgta taagtttcag aggcctttag tagcagatcc cgcccgggaa ttaaaccggg
    10921 acgaatacct gcgcctgtta gagacggcag agcggatggg aaagtacaga ttatatctga
    10981 ttcttcaaac tttgtgttca acgggaatca gaatcagtga gctgtcctgc attacgcggg
    11041 aggcagtaca gacaggaaga tgtgtggtaa ggctgaaagg aaaaagcagg attgtaatta
    11101 taccgcagaa attgcgagaa agactggatg cttactgcaa agaggaaaat attcagtcag
    11161 gtcaggtatt tctgtcaaga aaaggacagc ctctcgacag aagcaacatt tggggagaaa
    11221 tgaagcggct gtgccgaacg gcggaggtgg atgagaggaa agtatttcca cataatctgc
    11281 gtcacctgtt tgcacgtact tattataaaa aaaatcatga tattgtctat ctggcagata
    11341 ttctggggca cagcagtgtt gatacaacga gaatctacac gagtatcagc ataaaagaac
    11401 atgaaaaagt gctggaagat atggaattaa ctttttaaat tgaacacaat atgaaagaca
    11461 cagctgcttt gattgcagct gcaggaattg gaagcccttt tgacagaggc agaagcttgc
    11521 agatggagaa aataacgcgt tttttcaaaa aattactata ttttgtggct tcagtggttg
    11581 taatcaagct gtaaatttgc tatgctagaa cgagtgccct gaagaaaaag ctgaaaaggc
    11641 acagcaaaat aagtttgctg aatgataatt aggaggttgc ctgaaatgaa aagattaatt
    11701 gcatttttcg ggagtctggg attaatgctc gcctccagtc cgctgacagc tctggctgca
    11761 ggaaccggaa gcgcagggga gacgggatcc gttccgctgt ggatgtgtgt tccatttgcc
    11821 ggacttttat tgtgtattgc agtgctgccc cttgttaagg gagagtggtg ggagagccac
    11881 cagcctcatg cagtgctgtt ttggtctctt ttgtttgcgg ttccgtttgc tgtgaagttt
    11941 ggagccggga cagcgtctga gacaatttta gagtgtctta tcaatgatta tctgacattt
    12001 attgttttac tgtttggttt gttctgcgtg tctggtaata ttaccatgtc tggcgatcta
    12061 gccggttctc ccagagtgaa tgtgggactg ctggctctgg gaacactgct ttccagctgg
    12121 attggaacga cgggagccag tatgctgatg atccgtccgg tcattaaaat gaactcctgg
    12181 agaaaaagaa aacgtcatat tattattttc tttatctttt tggtatcaaa tatcggcgga
    12241 tgtctgacac ctatcgggga tccgcctctt ttaatgggct ttatgagggg agtgccattt
    12301 ttctggagtc ttcacctgct tccgattctt ctggtgaata tggctgtcct gctggcaatt
    12361 ttttatttta ttgatttgag ggcttaccga aaagacattg ctattggctt aaagccagat
    12421 atcagcaaac caggtacaga agtaaaactg agaggaaccc ataatttgat ttttctggca
    12481 gccattgtag gagcagtgat tctgagcgga acgcttcctg gccttcctgc ttttcaggat
    12541 gcggctggaa atgtaaaggg aattcatatt tttggggaag tagtgctttc ctacccggcc
    12601 attatagaga ttgtgattat actgatttca gcattcctgt ctttcaagac tacagaatcg
    12661 gagattcgtc gtgaaaatca ctttacctgg ggcgcaattc aggaggttgc cgtactcttc
    12721 attggtattt tcattaccat gcagccagct ctgatgcttt tgaaggccaa tggagctaat
    12781 ctgggaatta cagaaccttt tgagatgttc tgggcgacgg ggcttttatc cagttttttg
    12841 gacaacacgc ctacgtatct ggtattcctg acaacagcag gagctgttgg atttacagaa
    12901 ggactgacta ccgctctggg tgtgattcca attcagatgc tgactgctat ttcctgcggc
    12961 gctgttttta tgggagccaa tacttatatt ggaaacgcgc ctaactttat ggtgaaatcc
    13021 attgcagacg agaacggtgt acggatgccg tctttctttg gatatctgct ctggtccctg
    13081 gtgattctgg ttccggtttt tgccttggac atgctgttgt ttttcctgta gggaggtaat
    13141 ggacgatgag tggaaataca agtaatgaaa caaaaatcag agctttggct gagcgtatct
    13201 acgatctgga tgcccaggtt tatgcttcct taggttcttc tctgggccgt gtattcaacc
    13261 gcgacagaga gaggtgtgtc agagaactgg tttctctgat gatgacaagg ccagaaggaa
    13321 acctggtccg cagtgaaatt gctctgattg gaaatatggc cagaaccatt caggataagg
    13381 aagaacgccg cctggttatg acggagtaca atgacattct tcaggaggtc atggaacttc
    13441 ctaccagttt tgccagcgga gatgtggtga acctggagct ggcaaagctg aataccttta
    13501 atttaaaaaa caggtttaca gacaaggatc atctgattat ctgcatcggc tggacctatg
    13561 gaagcggagg cgtaaacatt ggcttcaagc tggctgataa attgaaaatc aacttctatg
    13621 acgcagagat tttcgaagcc gttttaaaac gtctggaggc ggagaaggat tctgtggaag
    13681 acaagggcgg atacaagatt gaatcgcccg gggagaaact tcagaatccc agcgatgcct
    13741 ttaagccgga gcgtcatttg acgctgcgcc agcatatgag gaagttcagc cgttttcacg
    13801 gtctgcccaa ggaggacgcg gttttcttta acgagagcga tctcctctgc gatatggcta
    13861 aaaaggaaga cttcgtggtg ctgggacgct gcagcgatgt gattatgaca aacaatcatg
    13921 tcccccatgt cagtatttat attacagcgc catttgagca gcgtattaag agagccatgg
    13981 agattgacag cacgatgact gtcaagcagg cagtccgtta cttaaagcac ctggatcgag
    14041 agcgttccaa acattatcgg ttctacacag gacgtcagtg gggaaacgcc aataactacg
    14101 atttgtgtat caacagcgcc agctatggaa ttgacggaac ggtagatttt atttataaca
    14161 tgattaacct ccggctggaa gagagcagga aagaagcggg agccagtcag taatttctta
    14221 cgttttctta catttttctt catttaattg tgccggttcc tgttttgtgg tataatttca
    14281 caaaatcagg accgtttggg gactttaaat ggggaggtag ttaatgtatc agatttctaa
    14341 ttttactgac aatgacgatg taaagattct cgctgagatg ggagcttttc aggtaatcga
    14401 gtatcagaga gacttgagcg tgtctccgtc ctctgcgatc acagcgtatt tcagctctga
    14461 gatgaatgtg agaaagcgcc agctggtctg ctatctggac aaatcccacg tgactatcca
    14521 ggcaggggct atgcagtgga tgttgggaaa tgtgaacgcc accacagggg taaagggagt
    14581 cggcgatttc tttggaaagg cagtccgcgg caaggccagc ggcgagtcgg cgattaaacc
    14641 ggagtacacc ggagacggag ttctggtgct ggagccgacc tataagcatc tgattttgat
    14701 ggataccgct tcatggggcg gaggcgttgt gctggacgac ggactgtttc tggcctgtga
    14761 atccagcctg aagcacaaag cggtgatgcg gtccaacttt tcctcagccg tagccggagg
    14821 agaaggcctg ttcaacctga gtctgaacgg ttcaggcgta ttctgtattg aatcagagtg
    14881 tccgaaggag gagcttatcg agattacgct gcaggacgac gtgctcaagg tagatggaaa
    14941 ccacgccatt gcctggagca aatctctgga gtttacagtg gagcgttccg gaaagactct
    15001 gattggatcc gccgcttccg gagaaggcct tgtgaacgtt taccgcggca caggcaaggt
    15061 gctgatgatg cctaccgcca agatgatcaa tatctaatcg gaaccggacg atgatagaaa
    15121 agactgctgc agcgcagatg atattctgcg gatgcggcag tcttttttgc gctctgctct
    15181 ttggaacgtt cccggccctg acgctgtata gaaaacatag ataaagacta tgattcatag
    15241 atattttcta tttgaaaaaa atctgcgatc cattacaatt ttaattgaat acattgggca
    15301 ggcgttttaa gagcgtctgc ttcggaggaa actatgctgg aagtaaaaca gttgtccaag
    15361 agttttgagg gaaattatgt gctgaagaat gtcagtcttt ccatagaggc cggagagatt
    15421 tacggcctga ttggagcaaa tgttccaaga tacatactga aagtatgatc cactacttag
    15481 aggattatat gtactgtact agaaagctgg ggctttatgt gcagttagta gcataaa
//
LOCUS       DBMDUW010000057        15368 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_2134_length_15368_cov_3.148556, whole genome shotgun sequence.
ACCESSION   DBMDUW010000057 DBMDUW010000000
VERSION     DBMDUW010000057.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 15368)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 15368)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15368
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2134_length_15368_cov_3.148556"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(50..1018)
                     /gene="cbiB"
                     /locus_tag="ACZPCR_09885"
     CDS             complement(50..1018)
                     /gene="cbiB"
                     /locus_tag="ACZPCR_09885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016285323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0048472 - threonine-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-phosphate synthase CbiB"
                     /protein_id="HIR1231222.1"
                     /translation="MKLYFAAAAAGFFLDLLFGDPHSLPHPVRLLGRLIESSETWIRR
                     MFPKTPGGELAGGGLLALWIVFITGGSCWLLLFLAGKAGTAVWFLTAAVMNYYLLAAR
                     SLRDESMKVYRPLTEGKVEEARLAVSMIVGRDTDRLDAEGITRAAVETVAENASDGVI
                     APLLYLLAGGPVLGWTYKAINTMDSMVGYRNDRYLYFGRAAARLDDLANLIPARLSAL
                     LMILSSFILGMNGKDAFKIWLRDRYNHKSPNSAQTESACAGALGIQLAGDAWYFGTLC
                     KKPFIGDPVRAVEYQDIPRANRLMYGAACFMMAWWGMGLMIINSIK"
     gene            complement(1050..1544)
                     /locus_tag="ACZPCR_09890"
     CDS             complement(1050..1544)
                     /locus_tag="ACZPCR_09890"
                     /inference="COORDINATES: protein motif:HMM:NF014351.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0043752 - adenosylcobinamide kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HIR1231223.1"
                     /translation="MVFIIGGSYQGKTECAFRRMRNQDKKESEIGAEAFSVFDARNMK
                     KSEKLEALPETERRQALNARRQVFQEISDSQTVLHLELLVRRLMEQDSETENWEEELF
                     SALQDREGAEKIVTADEIGYGIVPLDHFERAYREKEGRFCQRVAACAREVQRVICGVE
                     TRIK"
     gene            complement(1584..2408)
                     /locus_tag="ACZPCR_09895"
     CDS             complement(1584..2408)
                     /locus_tag="ACZPCR_09895"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008818 - cobalamin 5'-phosphate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0051073 - adenosylcobinamide-GDP
                     ribazoletransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HIR1231224.1"
                     /translation="MMGTYQEEERQEALFYTLMGSFVIAWSMYSRIPMPQIQWTKERM
                     RYTMCFFPLIGVLIGAAVAGFVFLSEKLGAGEIFTALVGTALPLVITGGIHMDGFLDT
                     TDARRSFLPRERKLEILKDPHAGAFAIIGCGVYLVLYGALFSELDFRGCLLFAGTFAA
                     ERALSGMSVVLFPMARQDGLAASFSQAALKRVVRLVMAGYLAASAAFFLIISEWLFDS
                     LIPGFLCLASSMLVFFWYYRMSVREFGGITGDLAGYFLQICELALLGASVLGVWIW"
     gene            complement(2462..2992)
                     /locus_tag="ACZPCR_09900"
     CDS             complement(2462..2992)
                     /locus_tag="ACZPCR_09900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HIR1231225.1"
                     /translation="MFAVITGGSGSGKSDYAERLSQMLEPGKKLYLATMMVWDREGEE
                     RVARHRRMRAGKNFETVEVYTELEQFCLPKPFQPGDASVLLECMSNLVCNEFYRQEKG
                     AAERIMDGICQLAGQCRHLIVVTNEVSADGRYYGEETERYRRLLGRINCFLGSRADLV
                     VEAVYGIPVVRKGRLP"
     gene            complement(3029..4144)
                     /gene="cobT"
                     /locus_tag="ACZPCR_09905"
     CDS             complement(3029..4144)
                     /gene="cobT"
                     /locus_tag="ACZPCR_09905"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008939 -
                     nicotinate-nucleotide-dimethylbenzimidazole
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HIR1231226.1"
                     /translation="MKSEAECRTGKSLTRQQLEKRLEGIVPPDRAAEREAWKRWDSVA
                     KPLRSLGVLEEAIASAAGIFGTWQVDFGKKAVVILCADNGIVEEGISQTGKEVTAVVT
                     SNFTRGDSCVCLMAESAGAQVFPIDIGVEKELCGLGEKYPLIHKNVRRGTRNFLKEPA
                     LTEEETVQALEIGIDLVKDLKNQGYGLIATGEMGIGNTTTSSAVVSAALKLDPYLVTG
                     RGAGLDSPGLLRKISVIRQGILLHQPDPEDGIDILSKVGGLDLAGMAGVFLGGALYRV
                     PIVMDGFISGAAALMAQRICPACAGYMLASHISSEPAGHLLLEALHKKAAISAGLCLG
                     EGTGAAALMPLLDMALRIYREMSTFKEIQIEDYKPLK"
     gene            complement(4155..5570)
                     /locus_tag="ACZPCR_09910"
     CDS             complement(4155..5570)
                     /locus_tag="ACZPCR_09910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009244442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042242 - cobyrinic acid a,c-diamide
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HIR1231227.1"
                     /translation="MKSILFAAPRSGSGKTLITCGFLEAVRRRGYHPAAFKCGPDYID
                     PMFHQYVLGIPGGNLDSFFLEADQVRQVFASRLKETGADLAVIEGVMGYYDGIGAVSK
                     RASSWEISVMTGTPSVLILDCKGASVSLAAQVKGFADFVDNSNIRGVILNRLSPMLYG
                     RLKPVIEKTGIKVYGYLPEMKECSLKSRHLGLFMPGEIEGLREKIGLLAEQIEKSLDM
                     DGLLKLAVNEENGLSGVFFSEKFTAEGRNAEEEIQKTVIAVARDEAFCFYYQENLSLM
                     ERLGAKLIYFSPLRDKSLPEADGYLFGGGYPENLAAELAANTSMLLSVREAHRKKIPI
                     LAECGGFLYLHRLLEGADGHQYPMAGLIDGEGFSTDRLSRFGYITLTGAEGQQIRGHE
                     FHYWDTTVSGGSWTAKKPMSDRSWSCMVEEEGLLAGFPHLYYPSNESWLRQWLREAGG
                     KHRRWKETAAGNDTEMIQQHI"
     gene            complement(5567..6136)
                     /gene="cbiT"
                     /locus_tag="ACZPCR_09915"
     CDS             complement(5567..6136)
                     /gene="cbiT"
                     /locus_tag="ACZPCR_09915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006781081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046025 - precorrin-6Y
                     C5,15-methyltransferase (decarboxylating) activity
                     [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0046140 - corrin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6Y C5,15-methyltransferase
                     (decarboxylating) subunit CbiT"
                     /protein_id="HIR1231228.1"
                     /translation="MTKSEVRAVSLSKLELTPESVLADIGAGTGSVSVEAALSWKVKS
                     VWAIEKNREAVELLRQNIARAERAGSGTIHLLEGEALALLTDPEIREQFRTGHRLTHA
                     FLGGTSGNMKQILEALLSLNPQMRIVINVIALESVAAAVAALKDLSIEAEIVSVQTAK
                     AKKAGSYHLMQGQNPVYIISFGGKDENEA"
     gene            complement(6226..7752)
                     /gene="cobK"
                     /locus_tag="ACZPCR_09920"
     CDS             complement(6226..7752)
                     /gene="cobK"
                     /locus_tag="ACZPCR_09920"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: protein motif:HMM:NF014613.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016994 - precorrin-6A reductase activity
                     [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HIR1231229.1"
                     /translation="MCRLLIFGGTTEGRQLAQFCADHRISAWVSVASQYGCDLLPSSE
                     YLRILVNRMDWQEMAEFMRDKQVRLVVDATHPYAKEVTGNIKRACMEEQILLLRCLRD
                     AEAESAEEEGVFYVPTAEAAVQMLGRTEGNVFVTTGSKELRAFTALADYENRIYARVL
                     PSPEAAEQCRGLGITGRHLICMQGPFSEELNAAMMGQIEARWMVTKETGKNGGYDEKI
                     RAARRNGASVIVIRREKENGFSVKEVEERILAFPRCQEADFSEKQENPVPEKEPLQVV
                     LAGIGPGSAGQMTLTVMEHIFHSRVLLGAPRMIESALKALDSLEQLFIHRNQNESSGR
                     KDRPRTEAVYQPEAVIRFLEGYQEGGMVTVLFSGDTGFYSGTKKLAAELKKRGISFTI
                     LPGISSAAYLAARLGISWERAEFLTAHGRILDTEELLCHMSGLQEPRWLFILLAGTEG
                     AGELCRRLTDLGYGNLQAAVGERLSYENERIRQGTVRELSETAADGLSILAVQAEPQD
                     "
     gene            complement(7745..8494)
                     /gene="cobJ"
                     /locus_tag="ACZPCR_09925"
     CDS             complement(7745..8494)
                     /gene="cobJ"
                     /locus_tag="ACZPCR_09925"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030789 - precorrin-3B
                     C17-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HIR1231230.1"
                     /translation="MEVRKMDKKIYVVGMGPGSLQDMTIRARQALEDCQVIAGYTVYV
                     DLIRELFPDKEFLTTPMKQETKRCRMALEQADQGKTTAMVCSGDAGVYGMAGLILELL
                     PEFPQVSVEVVPGVTAALSGGALLGAPLTHDFAVISLSDLLTPVETIEKRLRFAAQGD
                     FSICIYNPSSKKRAGYLKWACKILMEYQSPETVCGMVRQIGREGQAVEMMTLKELQNA
                     EADMFTTVFVGNSATRQVMGRMVTPRGYKDV"
     gene            complement(8485..9567)
                     /locus_tag="ACZPCR_09930"
     CDS             complement(8485..9567)
                     /locus_tag="ACZPCR_09930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HIR1231231.1"
                     /translation="MKLAGIAFTERGARLLERLLSRFQEEGEETEGTVSPSCAEAAGG
                     LSIRRETLKEWTKRQFQKADGLIFVGAAGIAVRACAPFVQDKTKDPAVIVIDETGRYA
                     VSLLSGHLGGANELALRAASIIGAEPVITTATDRNGLLAPDVFAKENGLEIEDMGLAR
                     EAAAALLRGEHLGFFSDFPVEGTIPAQLAFGKACRLNLWITRAGNVEKAPAESEEKKT
                     ERPSRYLKLLARDAVLGIGCRRGTKRETIEAAAESVLASQGLAMRDVKQIATIDLKQD
                     ETGLLEFASAHGTKICFYSLEELLKVPGDFSDSAFVKKTTGVGNVCERAAVLAAGENA
                     SLIVKKQTGHGVTAALAVCRRTVRWR"
     gene            complement(9564..10421)
                     /gene="cobM"
                     /locus_tag="ACZPCR_09935"
     CDS             complement(9564..10421)
                     /gene="cobM"
                     /locus_tag="ACZPCR_09935"
                     /EC_number="2.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046026 - precorrin-4
                     C11-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-4 C(11)-methyltransferase"
                     /protein_id="HIR1231232.1"
                     /translation="MVHFVGAGSGAVDLITVRGDRLLKQADVIIYAGSLVNPELLKGR
                     KENCLVYDSAKMTLEEVLSVIEEAEKRGDMTVRLHTGDPCLYGAIREQMDALDERRIA
                     YQVCPGVSSFCGAAAALNLEYTLPGISQSVVITRMEGRTPVPEREKIASFASHGATMV
                     IFLSTGLLKELSRELIRGGYQETTPAAIVYKATWPEEKAVVCQVGTLYETALREHITK
                     TALILVGEAVAHRRYERSRLYDPGFTTEFRKGTDVEPEAGTAKAEAAGPKETKPETGG
                     KETEWREHR"
     gene            complement(10444..11175)
                     /gene="cobI"
                     /locus_tag="ACZPCR_09940"
     CDS             complement(10444..11175)
                     /gene="cobI"
                     /locus_tag="ACZPCR_09940"
                     /EC_number="2.1.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006567059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030788 - precorrin-2
                     C20-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-2 C(20)-methyltransferase"
                     /protein_id="HIR1231233.1"
                     /translation="MKKTEGTKQGILYGVGVGPGDPELLTLKAVRILRECDVIAIPQE
                     SKEGCTAYQIARQAVPELDEKPCLPLPMPMTKDREKLAASHEAAAAKAAEQLAAGHTV
                     ALITLGDATVYSTYLYVHERIKRLGFETRIVNGIPSFCAAAARLDMPLVNGSQKLHIL
                     PASYHIEEALELPGVKVLMKSGRQMPKVKALLKEKGLEARMVENCGMEGEKTYQSLEE
                     IPDDAGYFSLLIAESSEEKQGGQRT"
     gene            complement(11243..12511)
                     /gene="cbiD"
                     /locus_tag="ACZPCR_09945"
     CDS             complement(11243..12511)
                     /gene="cbiD"
                     /locus_tag="ACZPCR_09945"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006776911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase
                     CbiD"
                     /protein_id="HIR1231234.1"
                     /translation="MEEKRQLKSGFTTGTCAAAAAMAAAQALAGGGKREYVSLMTPGG
                     REAAFEVLWQPECVKEAGDGQGGFWPGSESPEKQICMVRKDSGDDPDVTNGTLIGAAV
                     SFGENVQRAEESGEELPGIYSDHSQSPSVYLTGGIGVGRVTKKGLKCPVGYPAINPVP
                     RQMIAEAARTALWKLGCERPVYIEIFIPAGRKLALKTFNPRLGIEGGISVLGTTGIVN
                     PMSEQALIETIRLDIRVQAAENRTLLAVAPGNYGEAFLREEMGLSMDAFVKCSNFVGE
                     TFSMLKEEGVRQALFAGHLGKLIKVAGGVMNTHSKYGDRRMEILADCLAETWNSEEKR
                     SGRFALNRRREEVIGQILSMNTTDQAAEFLSAQGLLTSVMKTVTGRIKSVLESRFQIE
                     TEVIVFSGSAGILGMTEGAEAFAKRLKGRI"
     gene            complement(12593..12808)
                     /locus_tag="ACZPCR_09950"
     CDS             complement(12593..12808)
                     /locus_tag="ACZPCR_09950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007863968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003690 - double-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HIR1231235.1"
                     /translation="MAQNKKQETIDPAHLKPEDKLKFEIAEELGLGDKVINGGWKSLT
                     SKESGRIGGLITKRRREMKKQVLKENG"
     gene            complement(12949..13749)
                     /locus_tag="ACZPCR_09955"
     CDS             complement(12949..13749)
                     /locus_tag="ACZPCR_09955"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231236.1"
                     /translation="MRKKFLVFCCAAALAVSAAGCSPAEKAPAQETQTEQQTEAPETE
                     ESSQEAEGSAQEMAAAPQTVKFYGTVTRPEGSEGDQLLMNAAIEGVEGQQEVILNISE
                     ETLILDAVEGLPIKLEDIKDGDMVYSYMSPAMTASLPPQSFAYMILANIPADYRVPAL
                     EEVKELTVNEDGSAVVEAVSGTVYQVPADCVLLPYLTRNMVTIGSLTEGRNFLVWSEL
                     GEDGKEETASKIVMFQDGQLAFDTLDEAGEEAADTAETGAEDQLKPLS"
     gene            complement(13950..15038)
                     /gene="rpsA"
                     /locus_tag="ACZPCR_09960"
     CDS             complement(13950..15038)
                     /gene="rpsA"
                     /locus_tag="ACZPCR_09960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005945818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HIR1231237.1"
                     /translation="MSELSFEQMFEESSIKRLRAGETVTGQVISVSDDEIILSIAGSK
                     SEGIIPKSEYSNDTSVVLTEKVHVGDEMEAKVLKVNDGEGMAALSYKKLAADKGVKRL
                     KEAFENKEVLTEKVAQVVDKGLVVEVEGTRVFIPASMVSDTYDRDLSKYAGQEIEFVI
                     TEFNPSGRRSRIIGDRRQLLMEKKAAMQKELFERIEVGQTVEGVVKNVTDFGAFIDLG
                     GADGLLHISEMSWGRVENPKKVFKVGETVKALIKDINGEKIALSLKFPETNPWANAAE
                     KYAAGSVVEGKVARMTDFGAFVELEPGVDALLHVSQISREHVEKPSDVLSVGQVISAK
                     VVDFNEDDRKISLSMKALENADDAAEEN"
     gene            complement(15019..>15368)
                     /locus_tag="ACZPCR_09965"
     CDS             complement(15019..>15368)
                     /locus_tag="ACZPCR_09965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HIR1231238.1"
                     /translation="NYNKFQDLVEKISKTRYDILVLNTICNATQERQVEASQIASEVD
                     AMIVIGGKNSSNTQKLYEICRRECKNTYYIQTLSDLKPDKAGSVRSVGITAGASTPNN
                     IIEEVHTNVRIKF"
BASE COUNT         3293 a         4753 c         3184 g         4138 t
ORIGIN      
        1 tctgtctacg cagactgcat atgccatttt tagtcctgag tccttgttat cattttatcg
       61 aatttataat catcagtccc attccccacc atgccatcat gaaacaggcg gctccgtaca
      121 tcagtctgtt ggctctggga atgtcctggt attcgacagc tcttaccgga tctccaataa
      181 atggcttttt acagagtgtc ccgaaatacc aggcatcgcc ggccagctga atccccagcg
      241 ctccagcgca ggcagactct gtctgcgccg aattgggact tttgtgattg taccgatccc
      301 gcagccatat tttgaacgcg tctttcccat tcattcccaa aataaaagaa gacaaaatca
      361 tgaggagggc tgacaaacgg gcaggaatca ggttcgccag atcgtccagg cgggctgccg
      421 ccctgccaaa gtacagatat ctgtcatttc ggtatcccac catagagtcc atagtattga
      481 tcgccttgta cgtccagccc aggacaggcc ctccggccag aagatacagc agaggggcta
      541 tcactccatc tgaagcattt tctgccactg tttccacagc ggctctggta atgccctctg
      601 cgtccagtct gtctgtatcc cgtcctacga tcatggaaac tgccagacgc gcctcctcca
      661 cctttccctc tgtcaggggg cggtagactt tcatgctctc gtctctgagg gagcgggctg
      721 ccagaagata ataattcatc acagcggcag tcaaaaacca tacggctgtt cctgccttcc
      781 ctgcaagaaa cagcagcagc cagcagcttc ctcctgtaat aaatacgatc cacagagcca
      841 gcagtcctcc tccggccagc tctccccccg gcgttttggg aaacattctc cgaatccagg
      901 tctctgagct ttcaatcagc cttcccagca gccgtaccgg atggggaaga gaatgaggat
      961 ctccaaacag cagatccaga aaaaaaccag ctgcagcagc cgcaaaatac aatttcatct
     1021 tcttatatcc ttccctctat ctcgctttat tattttatcc gcgtctccac accgcatata
     1081 actcgctgta cttcccttgc acaggcagcc acacgctggc agaaccgccc ttctttttcc
     1141 cgataagcgc gctcaaaatg atcaagcggt acgattccgt atccaatctc gtctgctgtg
     1201 acgattttct ctgctccttc tctgtcctgc agagctgaaa aaagctcttc ttcccagttt
     1261 tccgtttctg aatcctgttc catcagcctt cttactaaaa gctccaggtg caatactgtc
     1321 tgggaatcag aaatctcctg aaagacctgt ctgcgggcgt tcagagcctg ccttctttct
     1381 gtctctggca gagcttccag cttttctgat tttttcatat ttctggcgtc aaatacagag
     1441 aacgcttccg cgcctatttc actttccttt ttgtcctgat tcctcatccg tctaaacgcg
     1501 cactctgttt ttccctgata gcttcctccg atgatgaaaa ccatttcttt cttcctcctt
     1561 catccagccg atcttttctt ttcctaccag atccacactc ccagaacaga agcgcctaaa
     1621 agcgccagct cacaaatctg cagaaaatag cctgccagat ctccggtgat acctccaaat
     1681 tccctgactg acatccgata ataccagaaa aagacaagca tagatgaagc aaggcacagg
     1741 aagcccggaa tcaggctgtc aaaaagccat tcgctgatga taaggaaaaa agccgcgctg
     1801 gctgccagat atcctgccat caccagccgg accacccgtt tcagcgccgc ctgggagaag
     1861 gaagcggcca gcccatcctg cctggccatg ggaaacagca ccactgacat tccgctcagc
     1921 gcccgttcag ccgcaaatgt ccctgcaaac agcagacagc ctctgaaatc aagctctgaa
     1981 aacaaagccc catagagcac aagataaact ccgcagccaa taatggcaaa tgctcctgca
     2041 tgaggatcct ttaaaatttc cagttttctc tcccttggaa gaaacgatct cctggcatct
     2101 gtcgtgtcga gaaaaccgtc catatggatt ccacctgtta tcacaagagg cagggccgtt
     2161 cccacaagcg ctgtgaaaat ttctcccgcg cccagcttct cagataaaaa aacaaagcct
     2221 gccacagccg ctcctattaa aactccaatc agcggaaaaa aacacatggt atatctcatt
     2281 ctctcttttg tccactgaat ctgaggcatg ggaatcctgg aatacatgga ccatgcgatt
     2341 acaaagcttc ccatcagcgt ataaaaaagg gcttcctgcc tctcttcttc ctgatatgtc
     2401 cccatcatcg ttcctctttt ccgccgtccg ggcctgtgat ttgttctgtt tccagcgcgc
     2461 ttcagggaag ccttcccttc cgcaccaccg gaattccgta aactgcttcc accaccaaat
     2521 cggctctgga tccaagaaag cagtttatcc tccccagaag ccttctgtac ctctctgttt
     2581 cttccccgta atacctgccg tctgccgaca cttcgtttgt taccacaatc aaatggcggc
     2641 actgccctgc cagctggcag atcccatcca taatgcgttc agctgccccc ttctcctgcc
     2701 ggtaaaattc attgcagacc aggtttgaca tacattctaa cagcacagag gcgtctcctg
     2761 gctgaaacgg cttcggaagg cagaactgct ccagctctgt atatacctca actgtctcaa
     2821 aattctttcc tgcccgcatt ctgcggtggc gggctacccg ttcctctccc tccctgtccc
     2881 acaccatcat ggtggccagg taaagttttt ttccaggttc cagcatttga gacagcctct
     2941 ctgcatagtc tgactttccg cttccgctcc ctcccgtaat tacggcaaac atcgcctctc
     3001 tccctttcct gaaccgtttt tgtctgcctt attttaaagg cttataatct tcaatctgaa
     3061 tttccttaaa ggtactcatt tccctgtaga ttctgagggc catatctaaa agcggcatca
     3121 gggcagccgc cccggttccc tcccccagac acagcccggc agaaatggcc gcctttttgt
     3181 gaagggcctc cagcagaaga tgaccggccg gctctgagga aatatgggag gccagcatat
     3241 atccggcaca ggccgggcag attctctgcg ccattaaagc cgctgcccct gaaataaatc
     3301 catccatgac aatgggaacc cggtacagcg ctcctcccag aaatacgcct gccatgccag
     3361 ccagatcaag ccctcccacc ttggacagaa tatcgattcc atcctccggg tctggctggt
     3421 gcagtaaaat cccctggcgg atcacagaaa ttttccgaag cagcccaggg ctgtcaagac
     3481 cggctccccg ccctgtaaca agatacggat ccagcttcaa agcagctgag acaacggcgc
     3541 tgctggttgt ggtatttcca attcccattt ctcctgttgc gatcagccca tatccctgat
     3601 ttttcaggtc tttcaccaga tcgatgccaa tctccagagc ctgcacggtt tcctcctccg
     3661 tgagagccgg ttcttttagg aaatttcttg ttccgcgcct gacattttta tgaatcaaag
     3721 ggtatttttc ccccaggccg cagagttcct tttccacgcc gatgtctatg ggaaacacct
     3781 gtgctccggc cgactcggcc atcagacaga cgcagctgtc tcctctggta aaattagagg
     3841 ttaccacagc cgttacctct tttcctgtct ggctgattcc ctcttccaca attccattgt
     3901 ccgcgcacag aatgacaacc gcttttttcc caaagtccac ctgccaggtg ccgaaaattc
     3961 ccgctgctga cgcaatggcc tcttccagca ctcctaagct tctcaggggc ttcgctacgc
     4021 tgtcccagcg tttccaggcc tctctctcag ctgccctatc aggaggaaca attccttcca
     4081 gccgtttctc cagctgctgt cttgtcaagc tctttcccgt tctgcactct gcctcgctct
     4141 tcatgtatgc ctccctatat gtgctgctgt atcatctctg tatcgtttcc cgctgccgtt
     4201 tccttccacc ttctgtgttt tccgccggct tccctcagcc actgtctcag ccacgattca
     4261 ttggatggat agtagagatg gggaaatccc gccaaaagcc cttcttcctc caccatacag
     4321 ctccagcttc tgtctgacat gggctttttc gctgtccagc ttcctcctga cacagtcgta
     4381 tcccagtagt gaaattcatg acctcgtatc tgctgcccct cggcccctgt caaggtaatg
     4441 tagccaaacc gtgacaggcg gtctgtggaa aatccttctc cgtctatcaa gccagccata
     4501 ggatactgat gcccgtcagc cccttccagc agacggtgca gatagagaaa gccgccgcac
     4561 tctgccagta tagggatttt tttacgatga gcctctctga cagagagcag catagaagta
     4621 ttggccgcca attccgccgc caggttttct ggatagccgc cgccgaacag atatccgtcc
     4681 gcttctggaa ggcttttatc cctgaggggg ctgaaataga taagctttgc tcccagacgc
     4741 tccatcaggc ttaaattttc ctgataataa aaacagaacg cctcgtctct tgccactgct
     4801 atgaccgtct tctgtatttc ttcttccgca tttcttcctt ccgctgtgaa cttctctgaa
     4861 aaaaaaacgc cggacagccc attttcttcg ttcacggcca gttttagcag tccgtccata
     4921 tccaggcttt tttctatctg ctctgccagc agtccgattt tttctctcag gccttctatc
     4981 tcccctggca tgaaaagccc cagatgacgg cttttcagac tgcactcctt catctccggc
     5041 agatatccgt agaccttaat tcctgttttc tctatcaccg gtttcagacg tccatacagc
     5101 ataggggata agcggtttaa aataacgccg cggatattgc tgttatccac aaagtctgca
     5161 aatcccttta cctgggcagc cagggaaacg ctggccccct tacagtccag aatcaggaca
     5221 gaaggcgttc cggtcatcac tgaaatctcc caggagctgg cccgtttcga taccgctccg
     5281 attccgtcgt aatagcccat cacgccttct ataacagcca gatccgcccc cgtttccttc
     5341 agacgggatg cgaaaacctg cctcacctga tccgcctcta aaaaaaagct gtccagattt
     5401 cctccgggaa ttcccagcac atactggtga aacatgggat cgatatagtc cggcccgcat
     5461 ttaaaggcag cgggatgata ccctctgcgc ctgacggctt ctaaaaagcc gcaggtaatc
     5521 aatgttttcc cgcttccgct tctgggcgct gcaaaaagaa tcgacttcat gcctcgtttt
     5581 catcctttcc tccgaaactg ataatgtaca ccggattctg tccctgcatc agatgatagc
     5641 ttcccgcttt ctttgccttc gccgtctgta cagacacaat ttccgcctca atggaaagat
     5701 ccttcagggc agccaccgcc gcagccaccg actccagggc aatgacgttg atcacaatgc
     5761 gcatctgcgg attcaggctt aaaagcgctt ccaggatctg tttcatattt cctgaagttc
     5821 cccctaaaaa ggcgtgggtc agcctgtgcc cggtccgaaa ctgctcccgg atttccggat
     5881 cagttaaaag cgccagcgcc tctccctcca gcagatgaat tgtgccggat cctgccctct
     5941 cagcgcgggc tatgttctgt ctcaaaagct cgacagcttc cctgtttttt tcaatggccc
     6001 acacagactt cactttccag gaaagagccg cctccacaga gacagaacct gttccggcgc
     6061 cgatatctgc cagaaccgac tctggcgtca gctccagctt tgaaagggac acagcccgta
     6121 cctcgctttt tgtcataggg actttcccac gtataaacca ttcatcccgc ataggcttct
     6181 ctcgctcctg tttctctttt tctaattttc ttgtctctct gacagctaat cctgaggctc
     6241 tgcctgcacg gccagaatgg acaggccatc tgccgcagtt tctgaaagct ccctcaccgt
     6301 cccctggcgg atcctctcat tttcgtaaga aagacgttct cctaccgctg cctgaaggtt
     6361 tccgtatcca agatcagtca gacggcggca cagctctcct gccccttctg ttccggccag
     6421 gaggataaac agccatctgg gttcctgaag accgctcata tggcagagca gttcttccgt
     6481 gtccaggatt cggccatggg cggtgagaaa ttctgcccgc tcccaggaaa tcccaagtct
     6541 tgcggccaga taggctgcag aggaaattcc tggaagaatc gtaaaggaaa tccctctttt
     6601 tttcagctct gcagccagtt ttttcgttcc gctgtaaaat ccggtatcgc cggaaaacag
     6661 aaccgtaacc attccgccct cctggtatcc ctccagaaag cggatcactg cttccggctg
     6721 gtagactgct tctgtccgtg gtctgtcctt acgtccagag ctttcgtttt gatttctgtg
     6781 tataaaaagc tgttccagac tgtccagcgc tttcaaagcg ctctcaatca tccggggcgc
     6841 ccccagcagc acgcggctgt gaaagatgtg ctccataacc gtaagagtca tctgtccggc
     6901 tgaaccaggc ccaatcccgg ctaaaaccac ctgaagaggt tccttctccg gaactggatt
     6961 ttcctgtttt tcagaaaaat ctgcttcctg acaacgcggg aaggcaagga tcctttcctc
     7021 cacctccttc accgaaaaac cattttcttt ttcccggcgt atcacaataa ccgacgcccc
     7081 gtttctcctg gcagcccgaa tcttttcatc gtagccgccg ttctttcccg tctcctttgt
     7141 caccatccac ctggcctcta tctggcccat catggccgcg ttcaactctt ctgaaaacgg
     7201 tccctgcata cagatcagat gtctgccagt gattccaagc ccccggcact gctctgccgc
     7261 ttccggcgac ggcagcactc tggcatatat cctgttttcg taatctgcca gcgctgtaaa
     7321 ggcccgaagt tccttgctcc ctgtggtcac aaatacattg ccctccgtac gccccagcat
     7381 ctgtaccgcc gcctctgctg tgggcacata gaatacccct tcctcctctg cgctctccgc
     7441 ctctgcatcc cgcagacatc tgagaagcag tatctgctct tccatgcagg cccttttaat
     7501 attcccggtc acttcttttg catatggatg ggtggcgtca acaaccagcc ggacctgttt
     7561 atcccgcata aactctgcca tctcctgcca gtccatccgg tttaccagta tgcggagata
     7621 ttctgaggag ggcagcagat cacagccgta ctgggatgcc acgcttaccc aggccgagat
     7681 tctgtgatct gcgcaaaact gcgccagctg gcgtccttcc gtcgtgccgc caaaaattaa
     7741 cagcctacac atctttgtag cctctgggcg tcaccatgcg ccccattacc tgtctggtgg
     7801 cagaattccc cacaaaaact gtggtaaaca tatccgcctc cgcgttctga agctccttta
     7861 aagtcatcat ctccactgcc tgcccctctc tgcctatctg ccttaccata ccgcagactg
     7921 tctcaggact ctggtattcc atcaaaattt tgcaggccca tttcagataa ccggctcttt
     7981 ttttgctgga cgggttataa atgcagatag aaaagtcgcc ctgggccgca aaacgaagcc
     8041 ttttttcaat ggtttccaca ggggtcagaa gatcgcttaa gctgatcacc gcaaaatcgt
     8101 gggttaaagg cgcgcccaga agagcgccgc cgcttaaagc cgccgttacg cccggaacca
     8161 cctccaccga cacctgggga aattccggaa gaagctctaa tattaaaccg gccataccgt
     8221 aaactcccgc atccccgctg cagaccatgg cagtcgtttt gccctgatct gcctgctcca
     8281 gggccatccg gcatcgttta gtctcctgtt tcataggcgt cgttaaaaac tccttgtcag
     8341 gaaacagctc tcttatcaaa tccacatata cggtatagcc tgcaatcacc tggcagtcct
     8401 ctaaggcctg tcttgcccgg attgtcatat cctgcagaga gccggggccc atgcctacca
     8461 cataaatttt cttgtccatt ttccttacct ccatctgacc gttctcctgc agacagccag
     8521 agcggcggtt acgccgtgtc ccgtctgttt ttttacaatc agggatgcgt tttctcccgc
     8581 cgccaggaca gccgctctct cgcagacgtt tcctactcct gtcgtcttct tcacaaaggc
     8641 tgaatctgaa aaatctcctg ggacctttaa aagttcctcc agcgaataaa aacagatttt
     8701 cgttccatgg gcgctggcaa actccagcaa tcccgtctcg tcctgcttca ggtcgatggt
     8761 ggcaatctgc tttacgtccc tcatggcaag tccctgggaa gccagaacag actctgccgc
     8821 cgcttcaatc gtctcccgtt tcgttcctct cctgcagccg attccaagaa ccgcgtctct
     8881 ggcaagaagc tttaagtacc gggaaggcct ctctgttttt ttctcctctg attcggcagg
     8941 agctttctcc acgtttcctg cccgtgttat ccacaggttc aggcggcagg ccttaccgaa
     9001 agccagctgc gccggtattg tcccctccac tggaaaatca gaaaaaaagc ccaggtgttc
     9061 gcctctcaga agggccgccg ccgcttccct ggccagaccc atatcctcta tctcaaggcc
     9121 gttctctttt gcaaatacat ctggagcgag caggccgttt ctgtctgtag ccgtcgtaat
     9181 caccggctcc gctcctatta tggaggcggc tctgagggcc agctcattgg cgccgcccag
     9241 gtgccctgac agaagggaga ctgcataccg tcccgtttcg tctatgacaa tcacagccgg
     9301 atccttcgtt ttatcctgga caaagggcgc gcaggcccgg actgcaattc ccgccgctcc
     9361 cacaaagata agcccgtccg ccttctgaaa ctgtctcttc gtccattcct tcagcgtctc
     9421 cctccgtatg gaaagaccgc ctgccgcctc cgcgcaggaa ggggaaacgg tcccttctgt
     9481 ttcctctcct tcctcctgga acctgcttaa aagccgctct aacagcctag ctccccgctc
     9541 tgtaaaggca attcctgcca gtttcatcta tgttctctcc actctgtctc tttgccgcct
     9601 gtttctggtt ttgtctcttt tggccctgcg gcctctgctt tggctgtgcc ggcctcaggt
     9661 tccacatccg tcccttttcg aaattctgtg gtaaagcccg gatcgtaaag cctggaacgc
     9721 tcatatctcc tgtgagccac agcctccccc accagaatca gggctgtttt cgtaatatgt
     9781 tcccgaagcg ccgtctcata gagcgtgccc acctggcata ccactgcctt ttcctccggc
     9841 caggtagcct tatagacaat agctgccggc gtagtctcct ggtatccgcc ccgaatcagc
     9901 tctctggaaa gctcttttaa aaggcctgtg ctgagaaaaa taaccatagt cgcgccgtgg
     9961 gaggcaaagg aagcgatttt ctccctctcc ggcaccggcg ttctgccctc catcctggtg
    10021 ataaccacgc tctgtgaaat tcccggcagc gtatattcca gattcagggc cgccgctgct
    10081 ccgcagaaag agctgacgcc ggggcatacc tggtaggcaa ttctcctttc gtccaatgcg
    10141 tccatctgct ctctgatggc tccatacagg cagggatctc ctgtgtgaag gcgcaccgtc
    10201 atatccccgc gtttctccgc ctcctcaatc acagacagca cttcttccaa agtcattttc
    10261 gcgctgtcat aaacaagaca gttctctttt cttcccttca aaagctctgg atttaccaga
    10321 gaaccggcgt atataatcac gtctgcctgt ttcagcagtc tgtctccccg cacagtgatt
    10381 aaatccacag ccccggaacc ggctcctaca aaatgtacca tctcagctca cctctcctta
    10441 ttttcacgtc cgctgtccgc cctgtttctc ctcagaggat tctgcaatca aaagagaaaa
    10501 atatcctgcg tcgtccggaa tctcctccag agactggtag gttttctctc cttccattcc
    10561 gcagttttct accatcctgg cctccaggcc tttttccttt aggagagctt ttactttggg
    10621 catctgccgt ccggatttca tcagcacctt tacgcctgga agctccagcg cctcctcgat
    10681 gtggtaggac gcaggcagaa tatgcagctt ctgagagccg ttgacaagcg gcatgtcaag
    10741 ccttgcggcc gccgcgcaga aagaaggaat tccgttgaca atcctcgtct caaagcccag
    10801 gcgtttgatc cgttcatgga cataaagata cgtagaatac acagtggcgt cccccaatgt
    10861 aatcaaggct actgtgtgcc ctgccgccag ctgttctgca gctttggcag cggctgcctc
    10921 atggcttgcc gccagcttct cccgatcctt tgtcataggc atgggaagag gcaggcatgg
    10981 cttttcatcc agctccggca ctgcctgtct ggcgatctgg taggcagtac acccctcctt
    11041 actctcctgc ggaatggcaa tgacgtcgca ttctctcaaa attcttacgg ctttcagggt
    11101 taaaagctcc ggatcgcccg gccccacccc tactccatag agaatgccct gctttgttcc
    11161 ttctgtcttt ttcatgctgt ccttacgaat cctttcataa tcttctgttt atcattttta
    11221 tatatttcgt cccattcaaa gcttatatcc ggcctttcag ccgtttcgca aaagcctctg
    11281 cgccttccgt catgcccaga atgcctgcag aacccgaaaa cacaatcacc tctgtctcta
    11341 tttgaaatcg gctttccaaa acagacttga ttcttcctgt caccgttttc atcaccgaag
    11401 tgagaagtcc ctgtgcagat aaaaattccg ccgcttggtc tgttgtgttc atggacaaaa
    11461 tttgtccgat gacttcttcc ctgcgccggt tcaaagcaaa acgcccagaa cgcttttctt
    11521 ctgaattcca ggtttctgcc aggcagtctg ccagaatttc cattctcctg tctccatatt
    11581 tggagtgagt gttcatgact cctcctgcca ccttgatcag cttgcccaga tggccggcaa
    11641 acagcgcctg cctgacgcct tcttccttca gcatggaaaa agtctctccc acaaaattgc
    11701 tgcatttgac gaaggcgtcc atggaaagtc ccatttcctc ccgcagaaac gcttccccat
    11761 aatttcccgg agctactgcc agtaaagtcc ggttttccgc cgcctgtacc cggatatcca
    11821 gccggatggt ttctatcaga gcctgctcgc tcatgggatt gacaatcccc gtagttccga
    11881 ggacggaaat ccctccttcg attccaagcc ttggattaaa cgtctttaac gccagctttc
    11941 ttccagccgg aataaaaatt tctatgtaaa caggcctctc acagcccagc ttccaaagcg
    12001 ctgttctggc tgcttctgca atcatctgtc tgggaaccgg attaatggcc ggatagccaa
    12061 ccgggcattt cagccccttc tttgtcaccc gtccaacccc gattccgcct gtcagatata
    12121 cggaagggct ctgcgaatgg tcgctgtaga ttcctggaag ctcttctccg ctctcctccg
    12181 ccctctgaac gttctcgccg aaggagacgg ccgctccgat aagagtcccg tttgtcacgt
    12241 caggatcgtc gcccgagtcc tttctcacca tgcatatctg cttctctggg ctttcagaac
    12301 caggccagaa gccgccctgc ccgtctcctg cttccttcac acattccggc tgccacaata
    12361 cctcaaacgc cgcttcccgg cctcctggag tcatcagcga aacgtattct cttttcccgc
    12421 ctcctgccag agcctgtgca gccgccatcg cggcggccgc ggcgcaggtt cctgtggtaa
    12481 atccactttt cagctgtctt ttttcttcca tggtatctcc cgctgttccc ggcttgcttt
    12541 ctgatgggac gctgtttttt ctgtccgctt aatgccctac tattatatgc gatcagccgt
    12601 tttctttcaa tacctgcttt ttcatttccc ttctgcgctt cgtaatcagg cctccgattc
    12661 ttccgctctc cttggaagtc aggcttttcc agccaccgtt tatcaccttg tctcccagtc
    12721 ccagctcctc tgcaatctca aatttcagtt tatcctctgg ttttaagtga gccggatcga
    12781 tagtttcctg ttttttgttt tgggccattg gtgttctcct ttctctgttt agcaggagta
    12841 ttcccttttt tatgaacgct atacagaagc aggatacata tggagcaaaa cagacagaaa
    12901 aagagagcgt tgttcaaacg cccccttttt tgtctcttat ttcttttatt agctgagagg
    12961 ctttaactga tcctccgctc ctgtctcagc ggtgtctgcc gcttcctctc cagcctcgtc
    13021 cagtgtgtca aatgccagct gtccgtcctg gaacatcaca atcttgctgg ctgtctcttc
    13081 cttgccgtcc tctcccagct cagaccatac caggaaattt ctgccctctg tcaggcttcc
    13141 tattgtcacc atatttctcg tcagatacgg aagcagaaca cagtctgccg gaacctggta
    13201 aactgtgccg gaaacagctt ccaccactgc gcttccgtcc tcgtttacag tcagctcctt
    13261 tacctcctcc agagctggaa cacggtaatc tgccggaata ttggccagaa tcatgtaggc
    13321 gaaggactga ggcggaaggc tggcggtcat ggccgggctc atgtaggaat aaaccatgtc
    13381 tccgtccttg atgtcttcca gcttaatagg aagtccctcc actgcatcta aaatcagggt
    13441 ctcctcagaa atattcagga ttacctcctg ctgtccctcc acgccttcaa tcgcagcgtt
    13501 cataagaagc tgatctcctt cggaaccctc cggccttgtc acagtgccat agaatttaac
    13561 cgtctgcggc gctgctgcca tctcctgcgc gctcccttct gcctcctgag agctttcttc
    13621 tgtttcaggc gcctctgtct gctgctctgt ctgagtctcc tgtgccggag ccttctccgc
    13681 cggtgaacat cctgccgctg atacggctaa tgccgctgca caacagaaaa ctaaaaattt
    13741 ttttctcata acatctctcc tctctatgcc ctcttttatg atacttgttc taccaaatat
    13801 ttcttaagag gcgttcactt tttgcttaca aatttctaaa ctaatttcta aacaattctg
    13861 tccttctcat ttccataatg caaaagaggc acagaaccgc ttctgcacct cttttgtaat
    13921 ctctatgaac agcaatcgcc gtaactttct tagttctcct cagcagcgtc gtctgcattc
    13981 tcgagagctt tcatgctcag gctgatcttt ctgtcgtcct cgttgaaatc aacaacctta
    14041 gcgctgatta cctggcctac gcttaatacg tcggatggct tctcaacatg ctctctggag
    14101 atctgggata cgtgaagcag agcatctacg cctggctcta actctacgaa tgcgccaaaa
    14161 tcagtcatac gggcaacctt accctctact acgctgccag ctgcgtactt ctcagctgcg
    14221 tttgcccacg gatttgtctc cgggaactta aggctcaggg caatcttctc gccgttaatg
    14281 tccttgatca gggccttaac agtctcgcct accttgaata ccttcttcgg gttctcaacg
    14341 cgtccccagg acatctcgga gatgtgaagg agtccgtctg cgccgcctaa gtcgatgaat
    14401 gcgccgaagt cagttacatt cttaacaacg ccctctacag tctggccaac ttcgattctc
    14461 tcgaagagct ccttctgcat agcagccttc ttctccatga gaagctgtct gcggtcgccg
    14521 atgattctgc ttcttctgcc gcttggattg aactctgtga taacaaactc aatctcctgt
    14581 ccggcatact tggataaatc tctgtcatat gtgtcggaaa ccatgcttgc aggaataaat
    14641 actctggttc cctcaacctc aacaaccagg cccttatcta caacctgtgc aaccttttct
    14701 gttaatactt ccttgttctc aaaagcctct tttaagcgct taacgccctt atcagcagcc
    14761 agtttcttgt aggataatgc agccatgccc tcgccgtcgt ttaccttgag aacctttgcc
    14821 tccatctcgt cgcctacatg aaccttctct gtcaggacaa cagatgtgtc gttagagtac
    14881 tcgctcttcg ggatgatacc ttcagacttg cttccagcga tgctgagaat gatctcgtcg
    14941 tcgcttacac tgataacctg accagtaact gtctctcctg cacgtaatcg tttaattgat
    15001 gattcttcaa acatctgttc aaaacttaat tctgacatta gtatgaacct cctcgataat
    15061 attatttggg gttgaagccc ctgctgtaat acctacgctg cgcacagaac ctgccttatc
    15121 aggttttaaa tcactcagtg tctggatata gtaagtattc ttacactccc gccggcaaat
    15181 ttcatatagc ttctgcgtgt tagaactgtt cttaccgcct atgacgatca tcgcgtctac
    15241 ctctgaagct atctgacttg cttccacctg tctttcctgt gttgcattgc aaatcgtatt
    15301 taaaacaagt atatcataac gcgttttaga aattttttca actaaatctt gaaatttatt
    15361 gtagttaa
//
LOCUS       DBMDUW010000058        15011 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_2185_length_15011_cov_5.050168, whole genome shotgun sequence.
ACCESSION   DBMDUW010000058 DBMDUW010000000
VERSION     DBMDUW010000058.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 15011)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 15011)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15011
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2185_length_15011_cov_5.050168"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            162..234
                     /locus_tag="ACZPCR_09970"
     tRNA            162..234
                     /locus_tag="ACZPCR_09970"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:195..197,aa:Asn,seq:gtt)
     gene            332..403
                     /locus_tag="ACZPCR_09975"
     tRNA            332..403
                     /locus_tag="ACZPCR_09975"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:365..367,aa:Glu,seq:ttc)
     gene            417..487
                     /locus_tag="ACZPCR_09980"
     tRNA            417..487
                     /locus_tag="ACZPCR_09980"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:449..451,aa:Cys,seq:gca)
     gene            577..1296
                     /locus_tag="ACZPCR_09985"
     CDS             577..1296
                     /locus_tag="ACZPCR_09985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HIR1231239.1"
                     /translation="MGSGRTQRQRSELRTAARCAFPHTLPILAGFLFLGMTYGIYMNV
                     SGFSFWYPMFMSMTIFAGSVEFVAVNLLLGAFDPLQALLMTLMLNARHLFYGISMLDK
                     YRGTGFKKVFLIFGMCDESFSINYTADIPKDVDRGWFMFFVTLFNYLYWVVGASLGGM
                     FGSLIHFNTEGLDFVMTAMFAVIFIEQWTKEKRHAGALLGLGAPLVCLSVFGSDRFMI
                     PAMAAILALLTLFKSQIEQEE"
     gene            1327..1653
                     /locus_tag="ACZPCR_09990"
     CDS             1327..1653
                     /locus_tag="ACZPCR_09990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transporter permease"
                     /protein_id="HIR1231240.1"
                     /translation="MTLTEQIITIGMVVLGTMITRFLPFLLFPAGKPVPKYVQYLGKA
                     LPSAVFGLLVIYCLKNVNLMQGSHGIPELLSLAAVAALHLWKRQMLLSIAGGTVFYMA
                     LVQRIF"
     gene            complement(1686..2462)
                     /gene="aroD"
                     /locus_tag="ACZPCR_09995"
     CDS             complement(1686..2462)
                     /gene="aroD"
                     /locus_tag="ACZPCR_09995"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015528706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HIR1231241.1"
                     /translation="MNPLKIRTVVFGKGSPKICVPIVGVNRAEILAAAAALKETPAHV
                     AEWRADWCSDILNENGTPNLTAVTDILRQLRAVLGNMPLLFTFRTAAEGGERDIDFQS
                     YKALNLAASGEGLADLADVELFTAGDAAEAFIEELHKRGVKVVVSSHDFHQTPDEEVL
                     IDRLCAMRKIGADLPKVAVMPQSRKDVLVLLKATETASSLLDCPIITMSMSGAGVISR
                     LCGEVFGSAMTFGSAGKASAPGQMDVQDLSVVLELLHKSL"
     gene            complement(2518..3855)
                     /locus_tag="ACZPCR_10000"
     CDS             complement(2518..3855)
                     /locus_tag="ACZPCR_10000"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009101 - glycoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HIR1231242.1"
                     /translation="MSQELPPVSGPLKILSITAQKPHSTGSGVYLTELVQAFHRKGCR
                     QAVLAGICRDDSVCFPDSVSFYPVYYQSEQLPFPICGMSDEMPYKSTRYQDLTPEMTE
                     QFFTAFRASLNRALAEFQPDLILCHHLYLLTALARETTLASSSNESSDFRPKVAGICH
                     GSDLRQFKKNPLARDYIREQIRNLDTIWCLHQEQKQEILRLFQCSPEKVKILGTGYNS
                     QIFKKTAEKAPKKEELPKNSPVLSSDSGPIRLIFAGKLSEKKGVKSLLRSLRLLPPDL
                     AKRLTLTLAGGWGNEQEFQEIRQLADQSRGCPCPVDFPGRLSQTELARQMNQSDLFIL
                     PSFYEGLPLVLIEALACGLRPICTDLPGIRPWMDENVSGHGILFVKPPVMENEDEPDA
                     ASLPAFEAELAAAVAQAAQAAFSLPENLDASLQNLSWDGLCRRLLDDMTEQAV"
     gene            4323..6998
                     /locus_tag="ACZPCR_10005"
     CDS             4323..6998
                     /locus_tag="ACZPCR_10005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007706748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HIR1231243.1"
                     /translation="MSENRKEYLLNYEEVMKGLDVTESGLTREEADKRLSEHGPNKLK
                     EGKKESLLHKFLSELMDPMILVLIAAAVVSGITAVHQGESFADTIIIMLVVVINAVLG
                     VYQESKAEAAIEALQQIAAATSKVIRGGHQMTVKSEELVPGDIVILEAGDSVPADARI
                     IECASMKVEEAALTGESVAVEKTESPVSAAENGDVPLGDRKNMVYMGSIVVYGRGKAV
                     VCATGMDTEMGKIADAIANAKEEETPLQIKLNQLSKILTIMVLGICVLVFGVNIARSI
                     MSGAGADSGLVLNTFMIAVSLAVAAIPEGLAAVVTILLSIGVTKMSKNHAIIRKLTAV
                     ETLGCTQIICSDKTGTLTQNKMTVVEHSSSDEAFLIKAMALCCDAELENGEAVGEPTE
                     CALVNDALKAGMPKDQLKKAYERTGEAPFDSMRKMMSTIHTNPDGGLIQFTKGAPDEV
                     LKLCTRAYVDGREVPMTEDVKKHILEENKKLADQALRVLCAAYKTYDIMPKDTAPAAI
                     EKNLIYLGLSGMIDPIRPEVKAAIAECRSAGIRPIMITGDHRDTAVAIAKQLGILDEG
                     QKAITGAELNGISDEELAQTIQNYSVYARVQPEHKVRIVKAWKKLGKITAMTGDGVND
                     APSIKSADIGVGMGITGTDVTKNVADMVLADDNFATIVSAVAEGRRIYDNIRKAIQFL
                     LSANLAEVISVFAATLMGFTILKPVHLLWINLITDCFPAISLGMEEAEKDTMQRPPRD
                     SRDGIFANGMGFDIVFQGVVITILTMAAYFLGHYMEAGVWEITESPDGMTMAFLTLSM
                     VEIFHSFNMRSRRHSIFALPRQNKYLVWSFIASLVCTTVVIYVPALREAFEFEHISLM
                     EYGAALFLSVMIIPIMEIEKAIERAIEKKHGVCLN"
     gene            7197..8564
                     /locus_tag="ACZPCR_10010"
     CDS             7197..8564
                     /locus_tag="ACZPCR_10010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005330285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HIR1231244.1"
                     /translation="MEKEKIEKQSAESSAGLHQNLGLPTAISTVVGCVIGSGIFFKPQ
                     AIYTVTGGAPGLGMLAWVITGLVSIAAALTFAEIAVLFPETGGIPTYLSRVYGPKAGF
                     LAGWVQVVLFYPAMVSALAVACAQQAALFIGDGFVVPCAVGVILLIVFLNTLGSRVGG
                     GVQVVFTICKMIPLILLMVFGFLWGKGHYPAFSPLLGEGVNPVSAVGQLMVAVLFAFE
                     GWTAVGAISGEMKNTKRDLPRAIIGGVSIITAVYFVMNLAYLQVLPAEEMAKLPAPAS
                     AVAVALFGEAGGKLVSAGIVISVFGACNGFVFSGSRVAYFMASQGLFPGSRSLSRLNK
                     NRVPGNCILLIGALGSLLSMTGQFNLLTDLAVFSSWTFYTLTFMAVIRYRNMRPDVKR
                     SYRVPGYPLTPAIAIGSGVFVIVNQLCLAGIRASLMSLGSIAVMAAGLAVYEGMRKRE
                     RKAGI"
     gene            complement(8693..11236)
                     /locus_tag="ACZPCR_10015"
     CDS             complement(8693..11236)
                     /locus_tag="ACZPCR_10015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HIR1231245.1"
                     /translation="MHMVKLRDDFYWTGVTDENLRVFDIIMYTEFGTTYNSYVLKAGD
                     KTILFETAKAKFFEDYVEKLKEIVDVHSIDYLVVSHTEPDHAGSVEKLLDLSPQMKIL
                     ATGCAIGFLKEIVNRDFVSIPVKDHQRMEIGNKTLQFLIVPNLHWPDTMYTFIEEEQI
                     LVTCDSFGSHYAHAGVLASTVPSQEDYLKAAKYYYDCIIGPFKPFMLKALNRVKTMDI
                     SMICTGHGPVLDTTDSIKTIMQKYEEWSTVINPNPKKTVIIPYVSAYGYTKELAEKIA
                     EGVKDSGDIDVRSYDMVEADKAAVEQELLFADGILFGTPTILGEALAPIWELTLSMFA
                     GTHGGKFAGAFGSYGWSGEGVPHILERLKQLRMKVDEGFRVRFKPSRSDLVGAYEYGY
                     QFGCRVLNIEACKPKKTGARTLVKCLVCGEIFDSSLEICPVCGVGKENFVPADIEENS
                     FSNNTKEYYVILGNGIAGLNAAKAIRERDKTGTVVMISNESCASYNRPMLTKTMLASL
                     TAEQIAVEPESWYEENDICQILGRTVVSVDTEKSEVILDDGSQIHFTRLIYALGSECF
                     IPPIPGSGREQVIAVRRISDVEKISGLLKRSKNAVVIGGGVLGLEAAWELKKAGLSVT
                     VLEAAPMLMGRQLDATAGSILEEISRKNGIAIHTGVSISSIDGDESGAVSGVSLSSGE
                     TFPADLVIVSAGVRANTGLAQEMGLKTEKAVVVNSRMETGMKHIYACGDCAEYKGANF
                     AIWPEASEQGRVAGANAAGDDLEYRPVSSALTFNGMNTSLYAAGDNGKNPNLLYKTVE
                     FKDMGKEQYRKFYFLNNRLCGVILIGDLSQMARMSEALEQHASYKEVAK"
     gene            11525..12598
                     /locus_tag="ACZPCR_10020"
     CDS             11525..12598
                     /locus_tag="ACZPCR_10020"
                     /inference="COORDINATES: protein motif:HMM:NF018684.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme inhibitor LprI family protein"
                     /protein_id="HIR1231246.1"
                     /translation="MRRDKITAAAFAAAAVLMFSGCSGRQEETAVETAEETAAETEAV
                     ESSGEAEAESAKESGPEELVIYDDTEQADDGLTFDDLKNIQFVFSSGAGGWSTLLDIR
                     PDGSFEGEYFDSDMGSTGEGYPNGTVYLCDFKGRFTEPEKIDEHTYAVKIASMEYKQE
                     AGTREIKDSILYEYTDVYGLDGADRILIHLPGTPLESLSEELRSWIGYYDLSAAEETE
                     LSFYVLDNEKEQLGFRGWDSFQGVRDFIENTEKWTSKLEEELETDSSLTQTDLNSKSQ
                     EIYELWDSALNQLWDVLEKSKTSQEMEKLLSEQRQWIKQKEAAAEDAGAAYEGRTLQS
                     MAVSQKAAELTKERVYELLEYLD"
     gene            12666..13229
                     /locus_tag="ACZPCR_10025"
     CDS             12666..13229
                     /locus_tag="ACZPCR_10025"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008371097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HIR1231247.1"
                     /translation="MEARKLIEILKTAERLKDTARHCYTSKGRRESVAEHSWMMTLMA
                     FFMRDEFPDADMDKVAAMCVIHDLGEAFTGDIPAFEKTEADEEREERLLMEWVSSLPD
                     PYAEKMKSLYEEMADRSTLEAKIYKAIDSLEAVLQHNLSDLSTWLPMEYELNQTYGED
                     KTAFSEYMRELRREAREDTVRKIREGK"
     gene            13230..13616
                     /locus_tag="ACZPCR_10030"
     CDS             13230..13616
                     /locus_tag="ACZPCR_10030"
                     /inference="COORDINATES: protein motif:HMM:NF039496.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5655 domain-containing protein"
                     /protein_id="HIR1231248.1"
                     /translation="MDTLKQDELFFFEQHREAYSLYEALEEELIRRFPETRIRVQKTQ
                     ITFSNRHVYACVSFMRVKKKAELPEPYLVLTLGLSYPLESDRAAVRTEPYPGRWTTHF
                     VLSSQSELDEELFGWVREAWDFAAEK"
     gene            13649..14032
                     /locus_tag="ACZPCR_10035"
     CDS             13649..14032
                     /locus_tag="ACZPCR_10035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009531526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HIR1231249.1"
                     /translation="MKIEHIAMYVNDLEQARQFFEKYFGGRSNDLYCNKKTDFRSYFI
                     SFEDGARLEIMTKPGLEDEEKKLARTGYIHLAFSVGSREAVDQLTERLRGDGCQVLSG
                     PRTTGDGYYESCVVGIEGCQIEITV"
     gene            14260..14709
                     /locus_tag="ACZPCR_10040"
     CDS             14260..14709
                     /locus_tag="ACZPCR_10040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HIR1231250.1"
                     /translation="MLMPSIFGENLFDDWMDFPFDRNFFEGRDPLYGKHAKNIMKTDV
                     RETDDTYELDIDLPGFKKEEVTAELKNGYMTISAAKGLDKDEKDKEGRYIRKERYSGS
                     CSRSFYVGEQISEEDIKARFEDGILKISFPKRDQKKMEENRYIAIEG"
BASE COUNT         3825 a         3243 c         4247 g         3696 t
ORIGIN      
        1 gtacggagct gactgttact aatcggtcga gggcttaacc aagaggttgg gtagagagaa
       61 gaaggatgga aaagatagaa agtaggttca atgtgtggtt ttgagggtat gtagaagtac
      121 ccaaataccg gagagagaag taagaatccg ggggaagata atcctcctta gctcagtcgg
      181 tagagcatgc ggctgttaac cgcagtgtcg ttggttcgag tccaacaggg ggagttttaa
      241 acacctcaac aaagaacttg attgacaatt gctcgaaatt gtggtaagat agcagagcga
      301 agcagttaag ctgtggagct ttaatcagta aggccccatg gtcaagcggt taagacatcg
      361 ccctttcacg gcggtaacac gagttcgaat ctcgttgggg tcatttaatt taatacggcg
      421 acatagccaa gtggtaaggc gtgggtctgc aacaccctga tcaccagttc aaatctggtt
      481 gtcgcctcta aagagtcctt gattttcaag gacttttttt atttctcaat gtatgctagc
      541 ttttgacagt gatttttccg cagggaggaa attcttatgg gcagcggacg tactcagagg
      601 cagcgatctg agcttaggac agcggccaga tgcgcctttc cgcatacgct tcctatttta
      661 gcaggctttt tatttttggg aatgacgtat ggaatttata tgaacgtgtc gggattcagc
      721 ttttggtatc ctatgtttat gagtatgacc attttcgccg gatcggtgga atttgtggca
      781 gttaatctgc ttttgggggc gtttgatcct cttcaggctc tgctgatgac gctgatgtta
      841 aacgcccgcc atttatttta cggcatctca atgctggata agtacagagg aactggattt
      901 aaaaaggtgt ttctgatttt cggcatgtgc gacgagagtt tttctatcaa ctatacagcg
      961 gatattccaa aggatgtgga caggggatgg tttatgtttt ttgtcactct gttcaattat
     1021 ctgtactggg tagtgggagc gtctcttggc ggaatgttcg gttctctgat tcattttaat
     1081 acagagggtt tggattttgt tatgacagcg atgtttgccg taatttttat tgagcagtgg
     1141 acaaaggaaa agagacatgc aggagctctc ctgggactgg gagcgcctct tgtgtgcctg
     1201 tctgtatttg gatccgatcg ttttatgatt ccggctatgg cggcgattct ggctctttta
     1261 acgctgttta aaagtcagat agaacaggaa gaatagaaat agaagaataa aaagaggagg
     1321 gaacagatga ctctaacaga gcagattatt acaatcggaa tggtggtgtt gggaacgatg
     1381 attacacgtt tcctgccgtt tcttttgttc ccagcaggga aacctgtgcc taagtatgtc
     1441 cagtatctgg gaaaggcttt gccgtctgcc gtattcgggc tgctggttat ctactgcctg
     1501 aagaacgtaa atctgatgca gggcagtcac ggaatcccag agcttttgtc tctggctgct
     1561 gtggctgctc tgcatttgtg gaaacggcag atgcttctct cgattgcagg aggcacagtt
     1621 ttctatatgg cactggttca gcggatattt taatgtctga cggacggcca gactgcaatg
     1681 cagatttaca gactcttgtg gagcagttcc agcacaacgg ataaatcctg tacgtccatt
     1741 tggcctggag cggaagcctt tccggcagat ccaaaggtca tggcggatcc gaacacctcg
     1801 ccgcagaggc ggctgatcac tccggcgccg gacatggaca tggtgataat ggggcagtcc
     1861 agaagggagg aggccgtttc tgtggctttc agaagaacca ggacgtcttt ccggctctga
     1921 ggcatcactg cgactttcgg caggtctgcg ccgatttttc tcatagcgca gaggcggtcg
     1981 attaaaacct cctcgtcagg cgtttgatgg aaatcgtggc tggagacgac gaccttaaca
     2041 ccgcgtttat ggagttcttc aataaaagct tccgctgcgt ctccggcagt gaaaagctct
     2101 acgtctgcta gatctgccag tccctcgccg gaagcggcca gattgagggc tttgtagctc
     2161 tggaaatcaa tgtctctttc gccgccttct gcggcggtgc ggaaggtgaa aagcagaggc
     2221 atattgccca gaacggcccg cagctgtctt aaaatatctg tgacagcagt caggtttggc
     2281 gttccgtttt cattcaagat atcggaacac cagtcggctc tccattctgc cacatgagcg
     2341 ggcgtttcct ttagagcggc ggcggcagcc agaatttcgg ctcgattgac gcccacaatg
     2401 ggaacgcaga ttttagggct tcctttccca aaaacaacag ttctgatttt caatggattc
     2461 atattggaca cctcgttttc agatttctct tttttcctgt ttacttttaa tgtttatcta
     2521 cactgcctgt tcggtcatat cgtctaacag ccgcctgcac aaaccgtccc aggagaggtt
     2581 ctgcagactg gcatccaggt tttccggcag agagaaagcg gcctgagccg cctgggccac
     2641 ggctgccgcc agttctgcct caaaggccgg gagagaggcg gcgtccggtt cgtcttcatt
     2701 ttccatgaca ggcggtttta cgaagagaat accgtggccc gacacgtttt catccatcca
     2761 ggggcggatg ccggggagat cggtgcatat aggtctgaga ccgcaggcca gggcttcgat
     2821 aagaaccagg ggaaggcctt cataaaagga gggaaggata aacagatccg actggttcat
     2881 ctgcctggcc agttctgtct gggacagtct tccaggaaaa tctaccggac agggacagcc
     2941 acggctctgg tctgccagct gtctgatttc ctgaaattcc tgctcatttc cccagccgcc
     3001 tgccagggta agagtcagcc gctttgccag atcaggaggc agaagacgga gagaccggag
     3061 caggcttttt acgccctttt tttcggaaag ctttccggca aatatcaggc ggatagggcc
     3121 tgaatcagag gaaagcacag ggctgttttt tggaagctct tccttttttg gggctttttc
     3181 agccgtcttt ttaaagattt ggctgttgta gccagttcca agaattttaa ccttttcagg
     3241 gctgcactgg aacagacgca gaatctcctg tttctgttct tggtggagac accagatggt
     3301 gtccaggttt cggatctgct ctctgatgta atcgcgtgcc aggggatttt tcttaaactg
     3361 gcgcagatcg gagccgtggc agataccggc cactttgggg cggaaatcag aagattcatt
     3421 agaactggaa gcaagcgtcg tttccctggc cagggcagtc agcaggtaca ggtgatggca
     3481 gagaatcaaa tctggctgga attctgccag ggcgcggttc agagaggccc tgaaggcagt
     3541 gaaaaactgc tctgtcattt caggggtcag atcctggtac cgcgtgcttt tgtagggcat
     3601 ttcatcggac attccgcaga tgggaaaggg aagctgctct gactggtaat aaacgggata
     3661 aaaagaaacg ctgtctggga agcatacaga atcatcccgg cagatgccgg ccagaacggc
     3721 ctgacggcag cctttgcggt gaaaagcctg aaccagctcg gtcagatata cgccgctgcc
     3781 agtgctgtgg ggcttctggg cagtgatgct caatattttt aaagggcctg aaacaggcgg
     3841 aagttcttga ctcataataa tactcctgta aaatgaaaaa taattctaag gctatcatac
     3901 aggaaaaacg aaaggtctgc cacaagaaaa aaattttatt gacatttctt taacagatgt
     3961 tatacaataa gagatgaaca agaagaactt ctgaatacag agttaaaagg gagtagttat
     4021 cttcgtacag tcaacaattc ccggctgtcc ggccggtggc tgtatgattt ctgtatacgg
     4081 ctttactttt ttacaggaag acaagacttt tagcatatga aacatatgct gagagtcttt
     4141 ttctttttca aaggacgtgc gcggaattct ttaaattcct tttttgggga atactagaga
     4201 ataactgttt ctcatccggc caaaaggctg gggagggccg gagttttgta tgaggcgtgt
     4261 tgttccttgt accctgacgc taaacagaag ttcaaataca gagagaaagg atggaaggac
     4321 gtatgagtga aaacaggaaa gaataccttc tgaactatga agaggtgatg aagggcctgg
     4381 atgtaacaga aagcggactt acgcgtgagg aagcagacaa gcggctttcg gagcacggtc
     4441 ctaacaagct gaaggaaggc aaaaaagaaa gtcttctgca caagtttttg tcagagctga
     4501 tggatccgat gattctggtg ctgatagctg cggctgttgt gtctggaatc acggcggttc
     4561 accagggaga gagctttgca gataccatta tcatcatgct ggtagtcgtg atcaacgcgg
     4621 ttctgggcgt gtaccaggaa tccaaggctg aggcggccat tgaggcgctg cagcagatag
     4681 cggcggctac atccaaggtg atccggggcg gtcatcagat gacagtaaaa tcagaggaac
     4741 tggttccagg cgatattgta attctggaag ccggagattc tgttccggca gatgcgagaa
     4801 ttattgaatg tgcttctatg aaggtggagg aggccgctct gactggagag tctgtggcag
     4861 tggagaagac ggagtccccg gtttctgccg ctgaaaacgg agacgtgccg ttaggcgacc
     4921 ggaaaaacat ggtgtacatg ggatccattg tagtctacgg acgaggcaag gcagttgtct
     4981 gcgctacagg aatggatacg gaaatgggca agattgccga cgcgatagca aacgccaagg
     5041 aggaggagac gcctcttcag attaagttaa accagctttc caagattctg accatcatgg
     5101 tattgggcat ctgtgttctg gtatttggtg taaatattgc cagaagcatc atgagcggag
     5161 ctggcgcaga cagcggcctg gtgctcaaca catttatgat agcagtatcc ctggctgtag
     5221 cggcaattcc ggagggactg gctgccgtag tgacgattct gttatccatc ggcgttacaa
     5281 aaatgtcgaa aaatcatgcg attatcagaa aactgacggc agtggagacg ctgggctgta
     5341 ctcagattat ctgttctgat aagacaggaa cgctcacaca gaataagatg accgtggtgg
     5401 agcactcctc atcagatgaa gctttcctga tcaaggcaat ggctctctgc tgcgacgcgg
     5461 agctggaaaa cggagaggct gtgggagagc cgacagagtg cgcccttgta aacgatgcct
     5521 taaaggcggg aatgccgaag gatcagctca agaaagcgta tgaaagaaca ggggaagcgc
     5581 cttttgactc catgagaaag atgatgtcca ccatccacac aaatccggac ggcggtctga
     5641 ttcagtttac aaaaggagcg ccggacgagg tattaaagct ctgtaccagg gcctatgtgg
     5701 acggacggga agtgcctatg actgaggatg tgaaaaaaca catcctggag gaaaataaga
     5761 agctggcaga tcaggccctg cgcgtgctct gcgccgctta taagacttat gacatcatgc
     5821 caaaggatac ggctccggca gcgattgaga agaatttaat ctatctggga ttgtctggaa
     5881 tgattgatcc aatccgcccg gaggtaaagg ctgctattgc cgagtgccgc agcgctggaa
     5941 tcagaccgat tatgattacg ggcgaccaca gagatacggc ggtagcgatt gcgaagcagc
     6001 tgggaatcct ggatgagggc cagaaggcca ttacaggcgc tgaattaaac ggaatttcag
     6061 atgaggagct ggctcagacc attcagaact attcggttta cgccagagtc cagccggagc
     6121 acaaggtgcg gattgtaaag gcctggaaga agctgggcaa gattacggcc atgacaggag
     6181 acggcgtcaa cgacgctccg tctatcaaat ctgcagatat cggcgttggc atgggaatta
     6241 cgggaactga cgttacgaaa aatgtggccg acatggttct ggctgacgac aattttgcca
     6301 caatcgtatc ggctgtggca gaaggaagaa ggatttacga caatatccgt aaggcgatac
     6361 agttcctgct ttccgcaaac ctggcggagg taatttccgt atttgcggcg acgctgatgg
     6421 gctttactat tttaaaacca gtccatctgc tctggatcaa cctgattaca gactgcttcc
     6481 cggcgatttc cctgggaatg gaggaagcgg agaaggatac catgcagaga cctccaagag
     6541 attccaggga tggtattttt gcaaatggaa tgggatttga cattgtattc cagggagttg
     6601 tcattacgat tctcacaatg gcagcttact tcttaggaca ttacatggag gcaggcgtgt
     6661 gggagattac agagtctcct gacggcatga cgatggcgtt cctgacgctt tctatggtgg
     6721 agattttcca ctccttcaac atgcgttcca gaagacattc tatctttgca cttccaaggc
     6781 agaacaaata tctggtatgg tcctttatcg cctccctggt atgcaccacg gtggtgattt
     6841 acgtgcctgc tctcagggaa gcctttgagt ttgagcatat ttctctgatg gagtacggcg
     6901 ctgcgctgtt cctgtccgtc atgatcatcc cgattatgga gattgagaag gccatcgaga
     6961 gggcgattga gaagaaacac ggcgtttgcc tgaattagtg gaggggaaaa attttacaga
     7021 gtcctgtgtg gcagattctt aagggaatct gctgtgcagg gctttttgtg ttttaacaga
     7081 aggccaagaa ttttaacaga tatactggtt gccgtgtgtt tttaaaaatg atatcataga
     7141 tgtcaaaatg ctgcgaagca caagagaaag cagaaagaaa acgaggaaca tatgccatgg
     7201 aaaaggagaa gatagaaaaa cagagtgcag agagttctgc cggcctgcac cagaatctgg
     7261 gcctgcccac agcaatttcc acagtagtgg gctgcgtgat tggttccggc atctttttta
     7321 agcctcaggc gatctatacg gtgaccggag gagcgccagg gcttggaatg ctggcctggg
     7381 tgattacagg gctggtgagc atagcggcgg ctcttacctt tgcggagatt gccgttttat
     7441 ttccggagac aggaggaatt ccaacttatc taagccgtgt ctacgggcct aaggcaggct
     7501 ttctggcagg ctgggtgcag gttgttttgt tttatccggc catggtttcg gccctggccg
     7561 tggcctgcgc tcagcaggcg gcgctgttta tcggggacgg ttttgtggtt ccctgcgcgg
     7621 taggcgtaat tcttttgatt gtctttttga atacgttagg ttccagggtg ggcggaggcg
     7681 ttcaggtggt atttaccatc tgtaagatga ttcctctgat ccttctcatg gtatttggtt
     7741 ttctgtgggg gaagggacat tatccggcct tttccccttt gctgggagag ggagtgaacc
     7801 cggtgagcgc cgtgggacag ctgatggtgg cagtgctgtt tgcctttgag ggatggaccg
     7861 ctgtgggagc tatttccggg gaaatgaaaa atacaaagag agatttgcca agagcgatta
     7921 tcggcggcgt ttccattatc acagccgttt attttgtgat gaatctggca tatctgcagg
     7981 tgcttccggc ggaggagatg gcgaagcttc cggctccggc ctccgcggtg gctgtcgctc
     8041 tgtttgggga ggccggcgga aagctggtat ccgcaggcat tgtgatatcc gtgttcggcg
     8101 cgtgcaacgg gtttgtattt tccggttcca gggtggccta ttttatggct tctcagggac
     8161 tgtttccagg cagcaggagt ctttcaaggc tcaataaaaa ccgcgttccg ggaaactgca
     8221 ttctgctgat aggagcgcta ggaagccttc tctccatgac cgggcagttt aatcttttaa
     8281 cggatctggc ggtattttcc agctggacct tctatacgct taccttcatg gcggtgatac
     8341 gctatcgcaa tatgaggccg gatgtgaaga gaagctaccg ggttccaggc tatccgctga
     8401 cgccggccat cgccattgga agcggcgtat ttgtgattgt caatcagctg tgtctggcgg
     8461 ggatccgggc gtcccttatg tctctgggca gtatcgccgt catggcggcc ggtttggcag
     8521 tgtatgaggg aatgagaaag agggaaagaa aagctggaat ataatgccag atagctcagc
     8581 tggcagagca ggcatgtcaa tacagcacat aagcatgcat aaacataaca tacagaaaaa
     8641 agcggggctg tgccgatggg tgcacagtcc cgcttttttg agacttttta tgctatttgg
     8701 ctacttcttt gtaggaggcg tgctgttcca gagcttccga cattctggcc atctgggaca
     8761 gatctccgat gagaatgacg ccgcacagac ggttgttcag gaagtagaat tttctgtact
     8821 gctccttgcc catatcttta aattctacgg tcttatagag gagattcgga ttctttccat
     8881 tgtctccggc agcgtagagg gaggtgttca tgccgttaaa ggtaagagcg gaggaaaccg
     8941 ggcggtattc cagatcgtcg cctgccgcgt tggctccagc gacgcggccc tgctcggagg
     9001 cctccggcca gatggcgaag ttagccccct tgtattcagc gcagtctccg caggcgtaga
     9061 tgtgtttcat tcccgtctcc atccggctgt ttacaactac tgccttctct gttttaaggc
     9121 ccatttcctg agccaggcct gtgttggcgc ggacaccggc agatacgatg acaagatcgg
     9181 ccgggaacgt ctctcctgat gaaagagaaa cgccgcttac agcgcctgac tcgtctccgt
     9241 cgatagaaga gatggagaca ccggtatgga tggcaatgcc gtttttccgg ctgatttcct
     9301 ccagaatcga tcctgccgtg gcgtccagct ggcgtcccat cagcatgggg gcagcttcca
     9361 gaaccgtgac ggaaagtcct gcctttttaa gctcccaggc cgcctccagg cccagcacgc
     9421 cgccgccgat gacaacggca tttttagagc gttttaacag tccggatatc ttttctacat
     9481 cgctgatgcg gcggacggcg atgacctgct ctctgccgct tccaggaatc ggcggaatga
     9541 agcattcgct gcccagggcg taaatcaggc gggtgaagtg gatctggctt ccgtcgtcca
     9601 ggatcacctc agatttttct gtatcgacag agaccacggt tctgccaagt atctggcaga
     9661 tatcgttttc ctcataccag ctctcaggct ccacggcaat ctgctctgca gtcagggaag
     9721 ccagcatggt tttcgtcagc ataggacgat tgtaggaggc gcaggactcg ttggagatca
     9781 tgacaacggt tcccgtctta tcccgttccc ggatggcctt ggccgcgttc aggccggcga
     9841 taccgtttcc aaggataacg tagtattcct tcgtgttgtt ggagaaggaa ttctcctcta
     9901 tgtcagccgg aacgaagttc tccttgccga cgccgcatac agggcagatc tccagggaag
     9961 aatcaaagat ttcgccgcag acgagacatt tcaccagagt tctggcgcct gtttttttcg
    10021 gcttgcaggc ttcgatattc agtacgcggc agccaaactg gtagccatac tcgtaggcgc
    10081 ccaccagatc ggaacggctt ggcttaaagc gtacccggaa tccctcgtcc accttcatgc
    10141 ggagctgttt taagcgctct aaaatgtggg gaactccctc gccgctccag ccgtagcttc
    10201 cgaaggctcc ggcaaatttg ccgccgtggg ttcctgcaaa catagagaga gtcagctccc
    10261 agataggagc cagagcctcg ccgagaatgg taggcgtacc gaacaggata ccgtcggcaa
    10321 agagaagctc ctgttccaca gcggccttgt ccgcctccac catatcgtag gagcgcacgt
    10381 caatatcgcc gctgtccttc actccctctg caattttctc cgccagctct ttcgtatagc
    10441 cgtaggcgct tacatagggg atgataaccg tttttttagg attgggattg attacagtgg
    10501 accactcctc gtatttctgc atgatcgttt taatggagtc tgtcgtgtcg agaaccgggc
    10561 catgtccagt gcagatcatg gaaatatcca tggttttcac ccggtttaag gccttcagca
    10621 taaagggttt aaacggtccg ataatgcagt cataataata cttggcagcc ttcaggtagt
    10681 cctcctggct gggaaccgtg ctggccagca cgccggcatg ggcgtagtgg gatccgaagg
    10741 aatcgcaggt tactaagatc tgttcctcct caataaaggt atacatggta tccggccagt
    10801 ggagattcgg aacgatcaga aactgcagag ttttatttcc aatctccatt cgctggtgat
    10861 ccttgacagg aatgctgaca aaatcgcggt ttacaatttc ctttaaaaag ccgatggcgc
    10921 agcccgtagc cagaattttc atctgcgggc ttaaatccag cagcttttca acgcttcccg
    10981 catgatccgg ctccgtatgg ctgactacca gatagtcgat gctgtgaacg tccacgattt
    11041 ccttcagctt ttcaacgtag tcctcaaaaa acttcgcctt ggcagtctcg aacaggatcg
    11101 tcttgtcgcc ggctttcaga acgtaggagt tgtaggtggt tccaaactct gtgtacatga
    11161 tgatgtcaaa gacgcggaga ttctcgtctg tgacgccggt ccagtagaaa tcgtctctca
    11221 gttttaccat atgcataagt gattctcctt ttctcgcagt caagaaccgc gtagagcgtt
    11281 cttgaaccat atagttaaaa aaatatcaat ctataataaa aatgattact gatattatta
    11341 tactctaaaa ccgacgcatg gtaaagagct tttttatatt gtggtaagaa aaccgccaaa
    11401 tatgcaaaaa gttctttgga agagggaaga ttcctgtttt ctgtatccag acagatcgtg
    11461 tataatggac ttatataggc ctggtctgct gtggccatgg cttgaagaaa gagaggatac
    11521 ggggatgaga agagacaaaa taacggcggc agcttttgcg gcagcggcgg ttctgatgtt
    11581 cagcggctgc tcgggcaggc aggaagagac ggcggtggag acagcagagg aaactgcggc
    11641 agaaacagag gctgtggaga gttcagggga ggcggaggct gagagcgcca aggagagcgg
    11701 gcctgaggaa cttgttattt atgacgatac ggagcaggcg gatgacggtc tgacctttga
    11761 cgatctgaaa aatattcagt ttgtattttc cagcggagcc gggggatggt ctacgctttt
    11821 agatatccgg ccggacggaa gctttgaggg agaatacttt gattctgata tgggcagcac
    11881 gggagaggga tatcccaacg gaacggttta tctctgcgat tttaaagggc ggtttactga
    11941 gcctgaaaag atagacgaac acacctatgc cgtaaaaatt gcttccatgg aatataagca
    12001 ggaggcgggg accagagaaa taaaagacag tattttgtac gagtatacgg acgtttacgg
    12061 cctggacggg gcggacagga ttctcattca tctgcctgga acgcctctgg aatctctgtc
    12121 agaggagctc agaagctgga ttggatatta tgacttgtcg gcagcggagg aaacagaatt
    12181 atccttctat gtgctggaca atgaaaagga gcagttagga ttcagaggct gggacagctt
    12241 tcagggcgtc agagacttta ttgaaaatac agaaaagtgg acgtcaaagc tggaggagga
    12301 gctggagaca gacagttccc tgacgcagac agatctaaac agcaagagcc aggagatcta
    12361 tgaattgtgg gattctgccc tgaatcagct gtgggatgtt ttggagaagt cgaaaaccag
    12421 ccaggaaatg gaaaaactgc tcagcgaaca gagacagtgg attaagcaga aggaagcggc
    12481 ggcggaagac gccggagcgg cctatgaggg aagaaccctg cagtctatgg cagtcagcca
    12541 gaaggcggcg gagcttacga aggaacgagt atatgagctt ttggaatatc tggattagct
    12601 gacagcagga aacagaaaga ggcagaggag agggacaaaa ggaaaagcga agggagaagg
    12661 atgggatgga agcgagaaag ctgatagaaa ttctgaaaac ggcagagagg ctgaaggata
    12721 ctgcgcgcca ttgctatacg tctaaggggc gccgggagag cgtggcggaa cacagctgga
    12781 tgatgactct gatggccttt ttcatgcggg atgaatttcc agacgcagat atggacaagg
    12841 tggcggctat gtgcgtgatt catgatctgg gggaagcctt taccggagat ataccggctt
    12901 tcgaaaagac ggaggcagat gaggagaggg aggagagact tcttatggaa tgggtttctt
    12961 ccctgcctga tccatacgca gaaaaaatga agtctcttta tgaggagatg gcggatcgca
    13021 gcacgctgga agctaagatt tataaggcca ttgacagtct ggaggctgtg ctgcagcaca
    13081 acctgtctga tttaagtacc tggcttccca tggaatatga gctgaatcag acctatgggg
    13141 aggacaagac agctttttcc gaatatatgc gggagctccg cagggaggcc agagaggata
    13201 cggtgaggaa aatacgggag ggaaaataga tggatacctt aaagcaggac gagctgttct
    13261 tttttgaaca gcacagagag gcatactcct tgtatgaagc gcttgaagag gaactgattc
    13321 ggcgttttcc ggagacgagg atacgggtac agaagactca gattacgttt tccaaccgcc
    13381 atgtctacgc ctgcgtctca tttatgcggg taaaaaagaa ggcggagctg ccggagccgt
    13441 atttggtgct gactttggga ctttcctatc ctctggaatc cgaccgcgcc gcagtgcgga
    13501 cagagccgta tcccggccgc tggacgacgc attttgttct gagcagccag tcagagcttg
    13561 acgaggagct gtttggctgg gtgcgagagg cgtgggactt tgcggcggaa aaatgagaag
    13621 aacagacgaa aacactggga gaaagcgcat gaaaatagaa catatcgcca tgtatgtcaa
    13681 tgatttagag caggcgagac aattttttga aaaatatttc gggggacgtt ccaatgatct
    13741 gtactgcaac aaaaagacgg atttccgctc ttattttatc agcttcgagg acggagccag
    13801 actggagatc atgacgaagc cgggacttga ggacgaagaa aagaagctgg ccagaaccgg
    13861 gtatatccac ctggcgttca gcgtgggaag cagagaggca gtggatcagc tgacagagag
    13921 gctgagagga gacggctgcc aggttctaag cggccccaga accacaggag acggatatta
    13981 tgaaagctgc gttgtgggga ttgagggctg ccagatcgag attacggtgt aaaaaaattt
    14041 aaaaaaatta gcacttacct cttgacagtg ctaataatat gtgttatatt acagctagaa
    14101 caaaggaagg ggaacaaaaa ggaagcctga aagaaggttt cacttcccaa gttcagataa
    14161 cagaaaaaca agtaacagcc tgcagacagc aggcgatgat attacagtcc cagccatgaa
    14221 acggaaccgt aacatctgaa aggataggag gtatgtttta tgttaatgcc aagcattttt
    14281 ggagagaatt tatttgacga ttggatggat ttcccatttg acaggaattt cttcgagggg
    14341 cgcgatccgc tgtatggaaa acacgcaaag aacattatga agaccgacgt cagagagacg
    14401 gacgatacct acgagctgga tattgacctt ccgggattca agaaagagga agtcacggca
    14461 gagcttaaga acggctacat gaccatcagc gcagccaagg gccttgacaa ggacgagaag
    14521 gacaaggaag gcagatatat cagaaaagag cgctacagcg gctcctgcag cagaagcttc
    14581 tatgtaggtg agcagataag cgaggaggat attaaagcca gatttgagga cggcatctta
    14641 aagatttcct tcccgaagag agatcagaag aagatggaag agaaccgcta tattgctatt
    14701 gaaggataat tgtcatcagc ggatgaataa gaaataagaa aatctataga cctggcggac
    14761 agccgtggaa cttttttgtg aaagttttac tgctgctgcc aggcctatag atttttttgc
    14821 attattctac tattttttct ggcttgccgg gataggtatt ttcctgtcct tccgcttcca
    14881 taaaagagag aaattatggt ataataggaa tacttagcga gatcttttcg agcttagtga
    14941 atgtggtata ataactccaa actatatcca aaccaggaag ggaattaatc tatgaatctg
    15001 gaatttaaac c
//
LOCUS       DBMDUW010000059        14860 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_2210_length_14860_cov_2.762924, whole genome shotgun sequence.
ACCESSION   DBMDUW010000059 DBMDUW010000000
VERSION     DBMDUW010000059.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 14860)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 14860)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14860
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2210_length_14860_cov_2.762924"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..527
                     /locus_tag="ACZPCR_10045"
     CDS             <1..527
                     /locus_tag="ACZPCR_10045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002564757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008184 - glycogen phosphorylase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HIR1231251.1"
                     /translation="TASKEASGTGNMKFMLNGALTLGTMDGANVEIVEEVGQENAFIF
                     GLSSDEVINYENNGGYNPVEIFNTDQEIRRVLMQLINGYFAPENPELFRDIYNSLLNT
                     KNSSKADTYFILKDFRSYAEAQKRVEEAYKNEGWWARAALLNTASAGKFSSDRTIEEY
                     VKDIWHLEKIQVEM"
     gene            783..1619
                     /locus_tag="ACZPCR_10050"
     CDS             783..1619
                     /locus_tag="ACZPCR_10050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIID/LytB domain-containing protein"
                     /protein_id="HIR1231252.1"
                     /translation="MIQMESSAAEQRMVILDRGGNAYPVPVEDYIIGMAAMQIPADYE
                     KETIKAQMIIARTYLYSLMGEESSIPESAIDADIMTEKEMRKAWGKESFLDCCQTFAD
                     AARETRGTVAAFEGTAIAPLFHRISAGKTRKGDVLHPYLASADCGKDVEAEGYLTSVI
                     FTPEEFCRRLNEMDHSLQLTPKEAYQSLQIVERDESGYVIQMKVGERIYTGEEIQYAL
                     GLKSAAFSFEEMGENIRCLVRGEGHGYGFDQWGANEKAKEGAAAEELLKYYYKNIELI
                     SE"
     gene            1660..2439
                     /locus_tag="ACZPCR_10055"
     CDS             1660..2439
                     /locus_tag="ACZPCR_10055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HIR1231253.1"
                     /translation="MKEKMNQLFKDKILLGMMVLGLLTIVAAAGAVRFRQGNDRVEEN
                     PYLEVPETGGYIVEQNPHTEEKTGKQDAEEQKEDIKVAGSSDAEYSREDRPDPKDLEG
                     DGKEDREAASRTGAKALALDFKEADKLAWPVTGNILLDYSMDATIYFPTLDQYKCNPA
                     LIIQSDVSSPVQAPANARVTECGANEEIGNYVVMDLGNEYTAVCGQLKDVKALEGEYL
                     CKGDIIGYVAEPTKYYATEGNNVFFELKQGGQPVDALDYLE"
     gene            complement(2560..3288)
                     /locus_tag="ACZPCR_10060"
     CDS             complement(2560..3288)
                     /locus_tag="ACZPCR_10060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015550059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTRA domain-containing protein"
                     /protein_id="HIR1231254.1"
                     /translation="MPKARYENIYRDLKEKIETNTFAYQEFLPPEHTLVQIYGCSRNT
                     LRRAVGLLVTDGYVQTMQGKGVRNIYQPAEQTSFTIGEIESFRESAARNSHTPLTEVL
                     LFTELTVNEKQSRAMGFPAGSDVYYIQRLHYLDGIPLILNHNYFLKEAAPGLTREIAE
                     QSIYQYLEETLRMTIVNSKRVMTVEKMTEIDEKYLKMNALDYNCVAVVSSQTFNSSGV
                     LFEYTQSRHRPDYFRFYDNAVRKG"
     gene            3453..5215
                     /gene="treB"
                     /locus_tag="ACZPCR_10065"
                     /pseudo
     CDS             3453..5215
                     /gene="treB"
                     /locus_tag="ACZPCR_10065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251017.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS trehalose transporter subunit IIBC"
     gene            5275..6741
                     /locus_tag="ACZPCR_10070"
                     /pseudo
     CDS             5275..6741
                     /locus_tag="ACZPCR_10070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243481.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
     gene            6830..7435
                     /locus_tag="ACZPCR_10075"
     CDS             6830..7435
                     /locus_tag="ACZPCR_10075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HIR1231255.1"
                     /translation="MNDRMNQEVLKKNFERHEFETSFFETREQAVNYLQAQIKGRKVA
                     FGGSVTLQEMGLFDALSKENEVIWHWNEPGAQTLARAREAQIYITSANGVSETGELVN
                     IDGTGNRVAQTLYGPEKVYFVVGKNKIEKDLSSALSRARNVAAPLNAKRLKTDTPCSK
                     TGEKCFDCGSEARICRATVILERPTRGMKAEIVFVNEALGY"
     gene            7493..7918
                     /locus_tag="ACZPCR_10080"
     CDS             7493..7918
                     /locus_tag="ACZPCR_10080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002565479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HIR1231256.1"
                     /translation="MNILFFLTPKSDVALIYEDDTLDEALEKMESYKYAAMPIISRQG
                     RYVGTITEGDLLWGIKNKYDFTFKGLDRVQVTEVPRRLDNQPVFADSDMEDLLDKAMN
                     QNFVPVLDDQKNFIGIVTRKDIIKYLSSQLKKKEKEAKA"
     gene            complement(7996..9435)
                     /locus_tag="ACZPCR_10085"
     CDS             complement(7996..9435)
                     /locus_tag="ACZPCR_10085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HIR1231257.1"
                     /translation="MNYAMIAYVIGWILNCEGFLMLLPCLTAVIYQETAGFSFAVAMA
                     LCFLFGVPLTVRKPKNMVFYTKEGFVSVSLSWIVLSVMGSLPFLFSGSITNPVDALFE
                     TVSGFTTTGASILSDVEALPRCILFWRSFTHWIGGMGVLVFLLSLLPLTGGYHMNLMK
                     AESPGPSVEKLVPKIQSTAKILYSIYVAMTILEVLLLLAGNMPLFDALTTTFGTAGTG
                     GFGIKNDSMASYSPYLQNVVTVFMILFGINFNFYFLLLMRKPKKAMKNEEVRCYLAII
                     AITISIITFNIRGLYPSIMEAFQQAAFQVGSIITTTGFATTDFNTWPQVSRTILVMLM
                     FVGACAGSTGGGIKVSRFVILLKTVNKELHLFLHPKGVRKISMDGKVVEHEVVRSINV
                     FMTAYVLVFAFSILLVGFDNHDLITNFTAVAATLNNIGPGLELVGPSQNFGLFSDPAK
                     CVLIFDMLAGRLELFPLLLLFVKDTWKRF"
     gene            complement(9448..10806)
                     /gene="trkA"
                     /locus_tag="ACZPCR_10090"
     CDS             complement(9448..10806)
                     /gene="trkA"
                     /locus_tag="ACZPCR_10090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018595623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HIR1231258.1"
                     /translation="MKIIIIGCGKVGRALTEQLVSENHNITVIDTNPKKIQTITEDLD
                     VMGISGNGAGITTLLEAGIAQADILISVTGSDELNLLCCLIARKAGHCQTVARVRNPM
                     YSQEIDFIKAQMGVSMIINPELTTAREIEKLLRFPAASKIDTFANGRIYLVKLKVDSQ
                     VPLDGVPVMELPSRSGSDVLVCAVERNDTVYIPDGNFILRKDDAISFVASKEQVHRFF
                     KHFSLPVKPIQSVMIVGGGTIGYYLAKQLLKNGVRVRIVENSLERCEALSSLLPGATI
                     IHGDGTDRHLLMEEGLGRAEAFVTLTNLDEENILLALFAKKNSKAKLISKVNRLAFDD
                     IIEGLDIGSVIYPKYLTTDYIIQHVRSMRHSAVNTIETLYRLLDNRVEALEFSILDTC
                     PVTDIPLSELKIRPGHLICCIRRGEQVLIPRGHDSIQVGDSVIVVTLERGQQNILDIL
                     EH"
     gene            complement(11330..11614)
                     /locus_tag="ACZPCR_10095"
     CDS             complement(11330..11614)
                     /locus_tag="ACZPCR_10095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231259.1"
                     /translation="MCCFRRYNNCGCQRRCCRCYTTCYDDANASGSCCGNTASNSCCS
                     SGNASYRNGYNDGYAAGCQAGYQNGYEAGIANCIMPLNGNGSSTGCGCSS"
     gene            11710..11955
                     /locus_tag="ACZPCR_10100"
     CDS             11710..11955
                     /locus_tag="ACZPCR_10100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231260.1"
                     /translation="MFQTDAIVQLENGTWSCRTQCCSVHTAEEARSGFIGPVRQISMF
                     ADLYREGKEIVLEGPDRETVEKLADILNHSAEELLEK"
     gene            complement(12098..12640)
                     /locus_tag="ACZPCR_10105"
     CDS             complement(12098..12640)
                     /locus_tag="ACZPCR_10105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002576053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HIR1231261.1"
                     /translation="MSTNLLLTYGGPDGEIGASMRYLSQRYTMPYAEGKGLLTDIGTE
                     ELAHMEIVAAIVCQLTKNLTPDQIEESGFGPYYIDHTTGIWPQAAGGVPFNACEFQVK
                     GDAITDLTEDLAAEQKARSTYDNILRVVKDPDVCDPIRYLREREIVHYQRFGEALRNL
                     QDHLDRKNFYAFNPEFDRVK"
     gene            complement(12661..14097)
                     /locus_tag="ACZPCR_10110"
     CDS             complement(12661..14097)
                     /locus_tag="ACZPCR_10110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HIR1231262.1"
                     /translation="MLIGAAYIRVSTDDQLDLSPDSQLDEIKKYAAANDIVLSPDYIF
                     MEQEGRSGKKAENRPEFQRMISTAKVKPKPFDCILVWKFSRFARNQDESTFYKGMLRK
                     KLGIDVISVSEPIMEGMYGRLIEMIIEWQDEFYSYNLGVEVKRGMTKKAELKGYQIVP
                     CLGYAAVGNGKPFVIVEDEYKIVEDIFRMYALENLDRTAIARRLNAQGKKAKRGNPFE
                     QRTITRILTNPFYNGTVNWNGISFQGSHETRRSITDLYDICQERLKQEFRPVKRRSIS
                     TCRHWLSGLLKCSVCGATMSYNGGGKSRPDAVFACWKYAKGLHKESCSVTVAKAERVV
                     IRSLEKILETGNFEYDRIPRPASEQDSSQKAAIEVKLERLALKEERIRSAYENGIDSL
                     EEYRTRKKQLVKERAELEAELASLEPADCSPAPSLEELLERVKTVHDLLCSPDVDFET
                     KGTALRSILKFIVFDRKADRFEFHYYIS"
     gene            complement(14280..>14860)
                     /gene="rhuM"
                     /locus_tag="ACZPCR_10115"
     CDS             complement(14280..>14860)
                     /gene="rhuM"
                     /locus_tag="ACZPCR_10115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="RhuM family protein"
                     /protein_id="HIR1231263.1"
                     /translation="FDELLERIRDIRASEKRVYLKVRDIFATSIDYDPKSEQADKFFK
                     TVQNKLHYSVHGHTAPELIVERANSSKDNMGLTSFKGSKVRKSDVTIAKNYLNKEEID
                     NLNRIVTMYLDYAEDQARQHIPMHMSDWEQRLNVFLQFMGRTVLSTNGTVTREEADDF
                     AKKQYELFDKHRKTLEHNTEVIDDLPELPKHS"
BASE COUNT         4063 a         3220 c         3921 g         3656 t
ORIGIN      
        1 ctactgccag caaggaggcc tccggcacag gaaatatgaa attcatgtta aacggcgcgc
       61 tgacgctggg caccatggac ggagccaatg tggagatcgt agaggaggta ggacaggaga
      121 acgcctttat cttcggactt tcctctgacg aggtaatcaa ctacgagaac aacggcggct
      181 acaatccagt ggagattttc aacacggatc aggagatccg aagagtgctg atgcagttaa
      241 tcaacggcta ttttgctccg gagaatccag agttgttcag agatatctat aactctctct
      301 taaacacgaa aaacagctca aaggccgaca catactttat tctgaaggat ttccgctcct
      361 atgcagaggc tcagaagaga gtggaggagg cctacaagaa cgagggctgg tgggcaagag
      421 cggctctctt aaatacagcc agcgcaggca aattctcctc tgacagaacc attgaggagt
      481 atgtaaagga tatctggcat ctggaaaaga tccaggtaga aatgtagaag atgttttaac
      541 aatataaaaa gaaggaactg ttttacttta atgaaaaagc agaatagttc cttttttgtt
      601 tcaagaataa agccttttct gcagtcataa attctgaagc cttcacatag actgttagag
      661 gcataaatgg caatgaatca ataaaggagt gatgtctcat gaagcggacg gcggccctgt
      721 gtataagtct tttattattt ccctatctgt ttaccttggc atggacaggc agggcggagg
      781 gaatgattca aatggaaagc agcgctgcag agcagaggat ggtaatcctg gatcggggag
      841 gaaacgccta tccggttcct gtggaagatt acattatagg aatggcggct atgcagattc
      901 cggctgatta tgagaaggaa acgataaagg ctcagatgat cattgccagg acgtatcttt
      961 acagcctgat gggggaggag agctccattc cggagtctgc cattgacgcg gatattatga
     1021 cagagaagga aatgcgaaag gcatggggga aagaaagctt tctggactgc tgccagacct
     1081 ttgccgatgc ggccagggag acgcggggaa ccgtcgccgc ctttgaggga acagcgattg
     1141 ccccgctgtt tcacagaatc agtgcgggga aaaccagaaa gggggacgtc ctgcatcctt
     1201 acctggcttc tgctgactgc ggaaaggatg tggaggcaga ggggtatttg acgtctgtga
     1261 tctttacgcc ggaggaattc tgccggcgtc tgaacgagat ggatcattcg ctgcagctta
     1321 cgcccaagga agcctatcaa agccttcaga ttgtggaacg ggatgaatcg ggatatgtga
     1381 tccagatgaa ggtgggagaa cgaatttaca caggagagga aattcagtat gcgctggggc
     1441 tgaaatcagc ggcattttcc tttgaggaga tgggggaaaa tatccgctgt cttgtccgcg
     1501 gagaaggaca cggctatggc tttgatcaat ggggggccaa tgaaaaggca aaagaggggg
     1561 ctgcggcgga ggaactgctg aaatattatt ataaaaatat tgaactgatt tctgaataag
     1621 ctgcctcggt ttggtaagaa tattaccgag gtgataagcg tgaaagagaa aatgaaccag
     1681 ttgttcaagg ataaaattct ccttggaatg atggtgctag gcctgctgac tatagttgcc
     1741 gcagcaggcg cagtcagatt cagacaggga aacgacaggg tggaggaaaa tccatatctg
     1801 gaggttccgg agacaggcgg atatatcgta gaacagaatc cgcatacaga ggagaaaaca
     1861 ggaaaacagg atgcagaaga gcagaaagag gacattaagg tggcgggaag ctccgacgcc
     1921 gagtactcca gggaggaccg ccccgatccg aaggatttgg agggagatgg gaaggaagac
     1981 agagaagccg cgtccaggac aggagcgaaa gctctggctc tcgatttcaa ggaggcagat
     2041 aagctggcct ggcctgtaac aggaaatatt ctcctggatt acagcatgga cgcgaccatc
     2101 tattttccca cgctggatca gtataaatgc aatccggcgc ttattattca gagcgacgta
     2161 agcagtcctg tccaggcccc ggccaacgca agagtcacgg aatgcggggc caacgaggag
     2221 ataggcaatt acgtggtcat ggatctggga aatgagtaca cagccgtctg cggacagctg
     2281 aaggatgtaa aagccctaga aggagagtac ctctgcaaag gagatattat cggctatgtg
     2341 gctgagccta cgaaatatta tgccacagag ggaaacaacg tattctttga gttaaagcag
     2401 ggagggcagc ctgtagacgc cctggactac ctggaatagc agaggaagaa taaaagaaga
     2461 ggctttcaga ggattttctg atggagcaga gggagaaggt ttcagcgcct tagatggagc
     2521 gcaaaacttc tccctctctc ttgttttatc ctttttttac tatccttttc ttacggcgtt
     2581 atcgtaaaac cggaaataat ccggacggtg gcgggactgg gtgtactcaa acagaacgcc
     2641 gctgctgttg aaggtctggc tgctgaccac agcgacgcag ttgtaatcta aagcgttcat
     2701 tttcagatat ttctcgtcaa tttccgtcat tttttctacc gtcatcacgc gtttgctgtt
     2761 tacaatcgtc atgcgcagcg tttcttccag atattgataa atcgattgct ccgcgatttc
     2821 cctggtcagg ccgggggccg cctctttcag aaaatagttg tggttgagaa tcagcggaat
     2881 accgtctaaa tagtggagcc gctggatgta gtaaacgtca gaccccgctg gaaatcccat
     2941 agcgcgggac tgtttttcat tcacagtcaa ttcagtaaaa aggagaacct ctgtgagcgg
     3001 tgtatggctg ttgcgcgccg cagattcccg gaagctctcg atttcaccaa tggtaaagga
     3061 ggtctgttcc gccggctggt agatgttgcg cacgcccttg ccctgcatgg tctgtacata
     3121 gccgtcagtg accagaaggc ccacagcgcg gcggagcgtg ttgcgggagc agccgtagat
     3181 ctgcaccaga gtatgttccg gaggcagaaa ctcctggtag gcaaaggtgt tcgtctcaat
     3241 tttctctttc aagtccctgt aaatattttc atatcttgct tttggcatac ggttacctcc
     3301 attacagttt attataggaa gctgccggga gaaagtcaac cgattgttta aacaaatatc
     3361 gggaagaagg gttgatatgt tcaaacaagt atgctataac aagaataaaa gaacatgttc
     3421 aaacaagttt tgctactgtg gaggaataag agatgggaaa atatgcagag gacgcccgcc
     3481 agctgctgcg cctggtggga ggaaaggaga acatcgcggc agtttcacat tgtatgacga
     3541 gaatgcgttt tgcgctggca gatccggaga aagccgatgt gaaagccata gaggcgctga
     3601 aatcggtcaa aggaagcttt acgcagtctg gacagtttca ggtgattatc ggaaacacgg
     3661 tcgctgactt ttacaacgaa tttgtcaaaa cggctgggat tgagggggca tccaaagacg
     3721 cggtcaagaa cgcggcaaag aagaaccaga atctcctgca gagattcatt gcagcgatgg
     3781 cggagatttt cgcgccgctg ctcccggcta tcattacagg cggcctgatt ctgggcttcc
     3841 gcaattgtat cgacagcctg tatctctttg agaacgggac aaagacgctc tgtgatttaa
     3901 gccagttctg ggcagggatt gacagctttc tctggctgat aggggaggcc attttccaca
     3961 tgctccccgt aggcatctgc tggtctgtga caaagaagat gggaacgact cagatgcttg
     4021 gcattgtgct gggactgacg ctggtatcag gacagctttt aaacgcctat gcagtagccg
     4081 gaacggcggc ggccgatatt cctaaatgga atttcggagc ttttcagatt aacatgatcg
     4141 gttatcaggg gcaggtgctt cctgcaattt tagcggcgtt tactctggtt tatctggaaa
     4201 aatttttcag gaaaattacg cctcaggtgg tttccatgat cgtcgttccg tttttcagcc
     4261 tgcttttatc tgttatggcc gctcactttg tgctgggctc cattggctgg aaggttggcg
     4321 aggccgtttc caccctcgta ttttccggaa ttacaggaag ctttaagatt gtatttgccg
     4381 ctgtgttcgg cgtttcctac gcgcctcttg tgattacggg gcttcatcat atgtccaacg
     4441 ccatcgacct gcagctgatt gcagattacg gcggaaccat gctgtggcct gcgtggccat
     4501 gggagtgact gcaaacgcca tcggcgtagg aggcattcca gggattctgt ccattcagcc
     4561 gccctatatg gcgtcctttg cagtctgcat ggcaattgca gcggcagcgc ccttccttct
     4621 gacggtggct gcaggaaaaa gaacgatggg gaaaccgcag gcggagcaga aggaggaaag
     4681 cgcagaggtt tccggagaag aaaacgcgcc tgcaaaagcg gaaagctcca ggccggatcc
     4741 agaggaaaca gaagagaaaa agggcatctt cactgcattt ttatctggga aagcgatttc
     4801 cttagaagaa gtgggagacg gagtgttctc atcaggaatg atgggagaag gcatggcgat
     4861 tcttccggat agcgatattt tgtgctcccc tgtagacgtg gagattgccg tgttaatgca
     4921 ggattcccgc catgcctgcg gcctgcgcct ttcaaacggc atggaacttg tgcttcacat
     4981 tggtatcgac accgtcagca tgaacggaga cggtttcgaa tatctggtaa aagaagggca
     5041 gaaggtcggc gcaggaactc cgctgatcaa atttgacaga gcgaagatta aggctgccgg
     5101 ccatcctgac gtgacgatct gcgtaattcc taataaggga agcgcggcag aaatccagtt
     5161 ccatacagga atggatgtaa aggcgaatga gacagttgtg gcagaattcc ggtaaatgat
     5221 gaaaaaatgg aacataacaa aaaagataaa aggataagag aaggacagga gacagacatg
     5281 gcagattaca gaaagatcaa tccagacttt ggaaccatgg aggatttaga actcttaatt
     5341 aaagaaagcc agaagcgcgg tatggggctt atgcttgata tggtgtttaa ccatacttcc
     5401 acagaacacg aatggtttca gaaggccctg gcaggagata agaaatatca gaattactat
     5461 ctgttcaggg acggaagcga ggattagccg cctacgaact ggcagtcgaa attcggcggc
     5521 tctgcatggg agtatgtgcc tcatctgaaa caatggtatc tccatttata tgatgtgacg
     5581 caggctgatt taaactggga taatcctgag gtgcgcgaag agctgaagga aatcctgcgg
     5641 ttctggaagg aaaaggggat ccgggccttt cgatttgacg tgatcaatct ggtttccaag
     5701 ccggagcggc tggaagatga ttcagaggga gacggccgca gattttatac agacggcccc
     5761 catatccacg aatacctgaa agagctggtg tgcagcgcag gaatagaaga ttttgtgaca
     5821 gtgggagaaa tgtcctccac ttcccttgag cactgtatca gatattcctc cccgaaggaa
     5881 aaggagctgt ccatgtgttt taactttcat catttgaagg tagattacaa ggacggagac
     5941 aagtggacgc tggctgttcc tgattataaa aagctgaagg agctgtttat gcagtggcag
     6001 ctgggtatgc aggcaggagg cggctggaat gccctcttct ggtgcaatca cgatcagcct
     6061 cacattgtaa gccggatggg agacgaaggg gactattgga aggagtcggc caagatgctg
     6121 gcaggcatga tccacttgat gaggggaacc ccttacattt accagggaga ggagattgga
     6181 atgctgaatg cccactattc ttctattggc cagtaccggg atgtggagag cctgaattac
     6241 tatcagatcc tgctgaggaa gggcaggacg gaggaggaag cgctccggat tctggcggcc
     6301 cgttccagag ataacggaag aactcctatg cagtggaaca gcgggacata tggagggttt
     6361 tcagaggcag agccgtggct ttccctgtcc ggcgcattca gggaggagat tacggcagag
     6421 tttcagaaag aggatcccga ttccattctg tccttctata aaatgctcat ttctctgaga
     6481 aagaaacgtc cggtaattgc agagggaacc atttccttcc tggagacggg aaacgacatg
     6541 acgcttgctt acgaaagaga gctgggatca gataaaatag ctgtgttctg caatctggga
     6601 aaggaagagc agaccgtgct cattggaaaa gagtggatag acggaaaact gctgcttgaa
     6661 aattacaggg agcggcagaa gactccggaa tcggaagttt ttgtgatgaa accatacgaa
     6721 ttgacagttc ttgaaaaata ataacgggaa aaattctctc cttcttttgt tttacagttg
     6781 acatcttacc tggaaaaagt taagatcata ggaggataaa agaagggacg tgaacgacag
     6841 gatgaaccag gaagttctta agaaaaattt tgaaaggcac gaatttgaga cctccttttt
     6901 cgagaccagg gaacaggcgg taaattatct tcaggctcag atcaaagggc ggaaggtggc
     6961 cttcggcggt tctgtcaccc tgcaggagat gggccttttc gacgctcttt caaaggaaaa
     7021 cgaggtgatc tggcactgga atgagccggg agcacagacg cttgccaggg ccagagaggc
     7081 gcagatctac ataaccagcg ccaacggcgt gtcagagaca ggagagctgg tgaatattga
     7141 cgggacggga aaccgtgttg cccagactct gtacgggcct gaaaaggttt actttgtggt
     7201 ggggaagaat aagatagaga aggacttgag ttccgccctg tccagggcca gaaatgtggc
     7261 cgccccgctg aacgccaaaa ggcttaagac cgatactccc tgtagcaaaa cgggagagaa
     7321 gtgctttgac tgcggcagcg aagcccgcat ctgccgcgcc acagttattt tagagcgccc
     7381 gacccgcggc atgaaagcgg agattgtatt tgtgaatgag gctctgggat actagcgcat
     7441 attttgatgc aggaggcgtc ctgcagaact ggaagaagga gagaattaca gaatgaatat
     7501 tttatttttc ttaacgccta aaagcgatgt ggctttaatc tatgaggacg atactctgga
     7561 tgaggctctc gagaagatgg agagctataa gtatgcggcc atgccgatta tcagccgcca
     7621 gggacggtat gtgggaacca ttacagaggg agatttgctt tggggcatta agaataagta
     7681 tgactttaca tttaaggggc tggatcgggt ccaggtgaca gaggttccca gaagacttga
     7741 caatcagccg gtgtttgcag attccgacat ggaggatctg ctggataaag ccatgaacca
     7801 gaactttgtt cctgtattag acgatcagaa aaactttatc ggaatcgtta cgagaaagga
     7861 tattataaaa tacctgagca gccagcttaa gaaaaaagaa aaagaggcaa aggcctgata
     7921 aagagaagag gagcagtttt cctgcggctt taagcggagc cgggaaagct gctcctctat
     7981 ttgctttatg cgcttctaaa atctcttcca tgtatctttt acgaagagca gaagaagcgg
     8041 gaacagttca agtcttcctg ccagcatatc aaaaatcagc acacatttgg caggatcaga
     8101 aaacaggccg aagttttggg acggtcccac taattccagg cctgggccga tattgttcag
     8161 cgtagcggcc acagcagtaa agtttgtgat taaatcatgg ttgtcaaagc ctaccagcag
     8221 gatagaaaag gcgaagacaa gcacataggc agtcataaat acattgatgg atcggactac
     8281 ctcatgttcc acaacctttc catccatgga tatcttgcgt actcccttgg gatgaagaaa
     8341 caggtggagc tctttattga ccgttttcag aaggatcacg aagcgggata ccttaattcc
     8401 gcctcccgta cttccggcgc aggcgcctac aaacatcagc atgacgagaa tcgtccggga
     8461 aacctggggc caggtgttaa aatctgtggt ggcaaagccg gtagtagtaa tgatagaacc
     8521 tacctggaag gccgcctgct gaaacgcctc catgatggac ggatacagcc cccggatatt
     8581 aaaggtaatg atggagatgg taatggcaat aatagccagg tagcagcgca cctcctcatt
     8641 tttcatggcc tttttcggtt tccgcatcag aagcagaaag taaaaattaa agttgattcc
     8701 aaacagaatc ataaatacag ttactacatt ctgcagatag ggcgaatagc tggccatact
     8761 gtcattttta atgccaaagc cgccggttcc cgccgttcca aaggtagtag tcagcgcatc
     8821 aaagagcggc atatttccag ccagcaggag caaaacctcc aggattgtca tagccacata
     8881 aatggagtat aaaattttag cggtagactg gattttcgga accagctttt ccacagacgg
     8941 tcctggactt tccgccttca tcagattcat atggtagccg cctgtcaggg gcagaaggct
     9001 taaaagaaag acaagaacgc ccatgcctcc gatccagtgc gtaaagcttc tccaaaataa
     9061 aatacagcgg ggcagagctt ccacatcgct taaaatgctg gctcctgttg tggtaaaccc
     9121 ggaaaccgtt tcaaacagag cgtccaccgg atttgtgatg gatccgctga acaggaaagg
     9181 gagagagccc ataacgctca gcacaatcca gctgagagaa acagaaacaa acccctcttt
     9241 tgtgtaaaaa accatgtttt tgggctttct cactgtcagg ggaacgccga acagaaagca
     9301 gagcgccata gctacggcaa aggaaaaacc ggcagtttcc tgatagatga cagccgttag
     9361 gcagggaagc agcatcagga agccttcaca attcaaaatc cacccgatta cataggcgat
     9421 cattgcataa ttcacagctc tacctcctta gtgttccaga atgtccagga tattctgctg
     9481 tccccgctcc agcgtgacta caatgacaga atcgcctacc tgaatggaat cgtggcctct
     9541 tggaatcagc acctgttccc ccctgcggat gcagcagatc aggtggccgg gccgtatttt
     9601 aagctcggaa agggggatat cagtcactgg gcaggtatcc aaaatagaaa attccagagc
     9661 ttccacccgg ttgtccagca ggcggtacag ggtttcaatc gtattgacgg cagaatggcg
     9721 catactgcgg acatgctgga taatgtagtc tgttgtcaaa tatttaggat agatgacgct
     9781 gccgatgtcc agaccttcaa tgatatcgtc aaaggccaga cgattgacct tggaaataag
     9841 ctttgctttt gaattttttt tggcaaagag agccagaaga atattttctt catccagatt
     9901 cgtcagggtg acgaatgcct ccgcccgtcc aagcccttct tccatcagaa gatggcggtc
     9961 cgtgccgtct ccatggataa tggtcgctcc cggcagcagg ctgctgaggg cctcgcagcg
    10021 ctccaggctg ttttccacaa tccttacccg gacgccgttt ttgagaagct gtttagccag
    10081 gtaatagccg atcgttccgc ctccgacaat cattacagat tgtattggct tgacaggaag
    10141 ggaaaaatgc ttaaaaaagc ggtgtacctg ctcttttgag gctacaaatg aaatagcgtc
    10201 atctttgcgc aggatgaaat ttccatcggg aatataaacc gtatcattcc gctccacagc
    10261 gcacacgaga acgtcgctgc cggatcgaga ggggagttcc ataaccggaa cgccgtcaag
    10321 gggaacctgg ctgtctacct tcagctttac gagataaatt ctgccgtttg caaatgtgtc
    10381 gattttgctg gcggcaggga agcgcagcag cttttcaatt tcccgggcag tagtcagctc
    10441 cggattaata atcatagaaa cacccatttg ggctttaata aaatcaatct cctggctgta
    10501 catgggattt ctgactctgg cgacagtctg gcagtgtcca gcctttctgg caatcagaca
    10561 gcagagcaga ttcagttcat cggaaccggt gacagaaata agaatgtcag cctgcgcaat
    10621 cccagcttcc aaaagagttg tgatgcctgc tccatttccg ctgattccca ttacgtctaa
    10681 atcctctgta atagtctgaa tctttttggg attcgtgtca ataacagtga tgttatggtt
    10741 ttcagaaacc agctgctctg tcagggcgcg cccaaccttt ccgcagccaa taataataat
    10801 tttcataaaa cagttactcc attccgacag tttagcttct gtactttaat atccacaggg
    10861 cgcctgaaat gactgatttg ccagacagag cgctcctgag acggatctta tggctattat
    10921 agcaaaaggg caggacaaaa taaagataag ataacgataa aattaagata gaataaaaat
    10981 aaaagagata agattaacaa aaagtaaaga aaagacggaa aacaataggg tcataacaag
    11041 aaaaagagcg gtaaaagagg aggagccgga cagatatctg cccggcttat tatgaaaaaa
    11101 atattactgt ctctctcgag aagtatttgg tttctatggt tattagtata gacagagttt
    11161 gtgtaccgaa tttggagaaa ttgtaaacaa tatttgaaca gaacgtaagt aatttatgaa
    11221 taggattggg ctcacagaga cggcggaagc cgccgcagga tagattcctg cagcggttct
    11281 gcctggcggc tgaaaggatg ccggaggact cggccgtctg gacaaagggc tatgagctgc
    11341 atccgcatcc ggtggaggag ccgtttccat tcagaggcat aatgcagttt gcaattccgg
    11401 cttcatagcc gttctgatag ccagcctggc agccggcggc atagccgtcg ttgtaaccgt
    11461 ttcgatagct ggcgtttcca gaggagcagc aggagttaga ggcagtattt ccacagcagg
    11521 aaccagaggc attggcatcg tcataacagg ttgtgtagca ccggcagcat cttctctgac
    11581 atccacagtt attatatctt ctaaaacaac acatataaaa atctccttga ttaattatta
    11641 tttataatat atggtatgta catcgggaca ataggttccg aaaaatgcgg agattttaca
    11701 ggaggaatta tgtttcaaac agatgccatt gttcaattgg agaatggaac ctggtcgtgc
    11761 agaacccagt gctgcagtgt ccatacggca gaagaagcca ggtcaggatt tattgggcct
    11821 gtccgtcaga tcagcatgtt tgcagacctg tatcgtgagg gaaaggaaat tgtactggag
    11881 ggaccagaca gagagacagt agaaaagctg gcggatattc tgaatcattc ggcagaagag
    11941 ctgctggaaa aataaaagaa gagtgaagaa agagggagag aagccctgaa gaaaaagaaa
    12001 gtttttctga attcagccag aaaagctttc tttttcgtac tcgttacagc tgcaaacgag
    12061 agatttcagg gatttttata aggcgggagc gatccggcta tttcacacga tcaaattcag
    12121 gattaaaggc ataaaaattt ttcctgtcca gatgatcctg cagatttctt aaggcttcgc
    12181 cgaatctttg gtagtggacg atttcgcgtt cccgtaagta tcgaatcgga tcgcagacgt
    12241 cagggtcctt tacaacacgg aggatgttgt cataggtaga gcgtgctttc tgttccgcag
    12301 caagatcctc cgttaaatct gtgatggcgt cgccttttac ctggaattcg caggcgttaa
    12361 aggggacgcc tccggctgcc tgcggccaga ttcctgtggt atgatcgatg tagtaggggc
    12421 cgaagccaga ctcctcgatc tgatccggag tcagattttt tgtaagctga cagacaatag
    12481 cagccacaat ctccatatgg gccagctctt ctgtgccaat atcggtcaga agtccctttc
    12541 cctctgcgta gggcatggtg taacgctggg aaagatagcg catggaagcg ccgatttcgc
    12601 cgtcaggccc gccgtatgtc agtaacagat tagtgctcaa aaccttgatt ttataagaaa
    12661 ttacgatatg taatagtgaa attcgaaccg atctgctttt cggtcaaata caatgaattt
    12721 taaaatgctg cgaagagccg tcccctttgt ttcaaagtcc acatcagggg agcagaggag
    12781 atcgtggact gttttgacac gttccagaag ctcttcaagc gatggggcag gagagcagtc
    12841 tgctggttcc agggaagcaa gctctgcctc cagctccgcg cgttccttta cgagctgttt
    12901 ctttcgtgtc ctatactctt ctaatgagtc gatgccgttt tcgtaggcgg atcggatacg
    12961 ctcttctttc agcgccaggc gttccagctt cacttcgatg gctgcctttt ggctggaatc
    13021 ctgttcagag gcgggccggg gaattctgtc atactcaaag tttcccgttt ccagaatctt
    13081 ttccagggaa cggattacga ctcgctctgc cttggctacg gttacagaac aggattcctt
    13141 gtggagcccc ttggcatatt tccaacaggc aaagacggca tccggacggc ttttgcctcc
    13201 gccgttgtag gacatggttg ccccgcagac agagcatttc aaaagtccgg agagccagtg
    13261 cctgcatgtg gatatgctgc ggcgcttcac ggggcggaat tcctgtttca gccgctcctg
    13321 gcagatatcg tacaaatcgg tgatggagcg gcgtgtctca tggcttccct ggaaggagat
    13381 gccgttccag tttactgtac cgttgtaaaa aggatttgta agaatcctgg taatggttcg
    13441 ctgctcaaat gggttgcccc gctttgcttt tttaccctga gcgttcaggc gccgggcgat
    13501 ggcagtcctg tccagatttt ccagagcata catccggaaa atatcttcta cgattttata
    13561 ttcgtcttcc acgataacga agggctttcc atttcctacg gcagcatagc caagacaggg
    13621 aacaatctgg tatcccttta gttctgcctt tttcgtcata ccccgcttta cctcaacgcc
    13681 cagattgtag gaatagaact catcctgcca ttcaataatc atttcaatca gccggccgta
    13741 catgccttcc atgataggct ctgacacgct gatcacgtcg attcccagtt ttttcctgag
    13801 catccccttg taaaaggtgc tttcatcctg gttcctggca aaccgggaaa atttccagac
    13861 gagaatgcag tcaaagggtt taggttttac cttcgctgtg gaaatcatcc gctggaactc
    13921 tggccggttc tcggcttttt tgccgcttcg gccttcctgc tccatgaaaa tgtaatcagg
    13981 cgacagaaca atgtcgtttg ccgcggcata ttttttgatt tcatccagct gggagtcagg
    14041 actcagatcc agctggtcat ccgtgctgac acggatataa gcagctccta tcagcatgat
    14101 atcatctcct tcatgtagtg acaatctatg tgattttggg tgcaaaaata acgccccttg
    14161 tcaggacgct ctggaaatga tataattcag gtgttcaagc tgattgtatc ttcctggagc
    14221 atccagcaag agaaaatcta tcaaaagccg ttcctggttg cagtcagggg cggtttttat
    14281 tatgagtgtt ttggaagttc tggcaaatca tcaattactt ctgtattgtg ttcaagggtt
    14341 tttcgatgtt tatcaaatag ttcatactgt ttttttgcaa aatcatcagc ttcttctctg
    14401 gtaacagtac cgtttgtact gagtaccgtt cttcccatga attgcaggaa tacattaaga
    14461 cgttgctccc aatcactcat atgcataggt atgtgctgac gggcctggtc ttctgcataa
    14521 tccaaataca ttgttacaat gcggtttaaa ttgtcgattt cctctttgtt taagtaattt
    14581 ttagcaatag taacatccga ttttcttact ttgcttcctt taaaagaagt taatcccata
    14641 ttgtcttttg aggaatttgc gcgttctact attagttctg gggcagtatg gccatgaaca
    14701 gaataatgaa gcttattttg aacagtttta aaaaatttgt cagcctgttc acttttggga
    14761 tcataatcta tagaagtagc gaatatatct cgcaccttta aatagactcg tttttcactg
    14821 gcacggatat ctcgaatacg ttctaataat tcatcaaaat
//
LOCUS       DBMDUW010000060        14517 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_2266_length_14517_cov_2.900180, whole genome shotgun sequence.
ACCESSION   DBMDUW010000060 DBMDUW010000000
VERSION     DBMDUW010000060.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 14517)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 14517)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14517
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2266_length_14517_cov_2.900180"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..626
                     /locus_tag="ACZPCR_10120"
     CDS             <1..626
                     /locus_tag="ACZPCR_10120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1231264.1"
                     /translation="FNVITGFYRPTEGDVVFAGRRITGMAPHRICSLGMARTFQNIRL
                     FKDLSVLDNVKVGLHNHHSYSTLAGIFRLPKYRKVEREMDERALELLKVFDLEKEFAV
                     KASNLPYGKQRKLEIARALATEPKLLLLDEPAAGMNPNETKELMDTIQFVRDNFDMTI
                     LLIEHDMKLVSGICEKLTVLNFGHVLTEGPTSQVLNNPEVVKAYLGE"
     gene            677..1387
                     /locus_tag="ACZPCR_10125"
     CDS             677..1387
                     /locus_tag="ACZPCR_10125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007864241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1231265.1"
                     /translation="MAMLEVKDLSVYYGVIQALKGISFEVEEGDVIALIGANGAGKTT
                     TLHALTGLIPVKSGSIVFEGKDITKVPGYKLVSMGIAHVPEGRRVFAQLTVLQNLKMG
                     AYTRNNKQESEETIQKIYKRFPRLEERKNQLAGTLSGGEQQMLAMGRALMSHPRLIVM
                     DEPSMGLSPLYVNEIFEIIKEISAEGTTVLLVEQNAKKALSIANKAYVLETGKIVLRG
                     DAKELMNNDQVKKAYLSE"
     gene            1622..2413
                     /locus_tag="ACZPCR_10130"
     CDS             1622..2413
                     /locus_tag="ACZPCR_10130"
                     /inference="COORDINATES: protein motif:HMM:NF014635.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF169 domain-containing protein"
                     /protein_id="HIR1231266.1"
                     /translation="MMDIIKEEAMKKLNASELLTRKPVGIKFLFTKEDYEACTAEPAK
                     AKMAYCVMVKIASMGVSLKTDIEMCSCGGGTRALGLEEPSERYYTGCEAYSFGLYRDL
                     AVAKQEVNSLTFCRHHTYGLLIQPLEAYEVYDPDVVILFSDSFGTMRLIQGYTYHYGP
                     QSNFKMTGNQALCSECTAYPYEMNSMNISMFCSGTRYLAGWDNSEIGIGMPYGIFTGV
                     CDGIYRSANGVERDCRKAVLRANLKEAGLKDPGLVDGQAYYMMQK"
     gene            2430..3236
                     /locus_tag="ACZPCR_10135"
     CDS             2430..3236
                     /locus_tag="ACZPCR_10135"
                     /inference="COORDINATES: protein motif:HMM:NF012738.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1231267.1"
                     /translation="MKQKAALSALAVRIFLILSVLALWEWGVRSSRLPDFYISYPSEI
                     AMDLWDFITSGELWKHASVTLQEAFAGLFGGSIAGIAAGILLGQFPFLGRIFKPIITA
                     VHGIPQLTLAPVYILWFGIGMQSKIFLAGLSAFFCVFFSTYGAIFDMEPKLIESASLL
                     GAKKTQILWMVVLPTCTPWILSGIRSGFSASLIGAIVGEYMGAGAGFGWMVAYATSYF
                     NMKRVMSCIFILLLLGLVLNFGLDRVEEALLKWRPRASLNIGEEKEQNDH"
     gene            3270..4364
                     /locus_tag="ACZPCR_10140"
     CDS             3270..4364
                     /locus_tag="ACZPCR_10140"
                     /inference="COORDINATES: protein motif:HMM:NF024772.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIR1231268.1"
                     /translation="MRKWISLMCAAGIAAAALMGCSGAETAGKNETKAAAEAAAGESA
                     ESLSSEETKKEEDKKELTKIVVSEFRGICWASAYAAEQLGYFEEEGLDVEFMLYKDGP
                     IAFQGMHAGDSDFCLLSAEPVMTAYDEGMESYLLLTNTNRRTYAFAGAADIKTAADLK
                     GKTIFAGMPGSAPYSFVLSMLKSAGLSENDVNFINLDYGSAIVALGEKQVDGIFFDVY
                     NKAILEETVPDANILLDCTDTQTHEALYGSQFCQTSIVTCTKKFAEENPETVQAFVNA
                     SSRALKWISEHTSKELAELISPMYDSMTVDELTAKFECIKDTFSETGEIIPEGYETME
                     SFCLDQGLIENSIPYEDIVASDFMDAAIEK"
     gene            4398..5426
                     /locus_tag="ACZPCR_10145"
     CDS             4398..5426
                     /locus_tag="ACZPCR_10145"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004079976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1231269.1"
                     /translation="MAYISFEQIEKYYGSQHVLKNLSLSVDKGEFVTLLGPSGCGKST
                     LLRCLAGLESISSGRILLDGEEITHVPPRQRNVGMIFQQYSLFPTMNVYNNIAFGLKI
                     QGVSKEEARLRIAEALKMADLAGSENKYPSQLSGGEQQRVALCRCIVTKPKVLLMDEP
                     FSAIDAKLRKALQKRIKEIHRELGMTTIFVTHDQDEAMSMSDTIHLMNRGIVEQSARP
                     LELYAHPKTAFAASFMGNYNMMTAEQFRSVTGDQWRRDVCIRPELIEIFGDSVEDLEQ
                     RKEGYTLSGTVTERIPQGNTVLYYVTVSDLQFKVSRLFNSPAFFEEGQKVCLFIPRDA
                     VLQYEKET"
     gene            complement(5532..6386)
                     /locus_tag="ACZPCR_10150"
     CDS             complement(5532..6386)
                     /locus_tag="ACZPCR_10150"
                     /inference="COORDINATES: protein motif:HMM:NF025865.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HIR1231270.1"
                     /translation="MKYYELAIKRKSTRDFKDKKVAAQTLNQIKDYAGQCKRLLPGLP
                     AEWKVLEGNPGNLSGTAGYSGFMIEAPSYLLLLSGQEDGALENAGYMGEDMVLKLTEL
                     DLDSCWITITDPALLKQRLHLDTELEPLALIAFGYGKPEGGTRLDIKSPASVHMKQRN
                     GQIAPKLYLEDAVFGGAWGQKSDLADWEPDSDLYRAFIAACCSPSVLNRQPYRFILDH
                     DVVSLVLLEDEMTSPEHAKLNAGIVMLHFAEVLSQNTGHPGRWQLGTPEKSYELPEGA
                     AFAGWFRI"
     gene            6568..8043
                     /gene="spoIVA"
                     /locus_tag="ACZPCR_10155"
     CDS             6568..8043
                     /gene="spoIVA"
                     /locus_tag="ACZPCR_10155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008725461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HIR1231271.1"
                     /translation="MENFNVYRDIKARTDGEIYIGVVGPVRTGKSTFIKRFMEQMVLP
                     EMEDGHAKERARDELPQSAAGKTIMTTEPKFIPKEAVEIPLGDGVEAKIRLIDCVGFM
                     VDGAAGHIENDTERLVKTPWFDYEIPFTQAAELGTRKVITDHSTIGLVITADGSFGEI
                     KRPSYMEAEEKTVRELKALGKPFLILLNSMRPYSDETKVLAGQMEEKYGVQVMPVNCE
                     QLKKEDIRRIMETVLTEFPVAEMDFFIPKWLEILPQEHWLKIHVVQAVKELMKKISRM
                     KDIGGELPVPSDGPIRRIKIRGMKMADGSVSVDIEVDDSCYYQILSDYTGVEIGGEYQ
                     LMQTLKRLAAMEREYEKVGDALSQVRLKGYGVVTPDRSEIVLDEPQLIHHGNKYGVKM
                     KAQAPSINLIKAHIETEIAPIVGSEQQAEDLIEYIKANAKESEDGLWNTNIFGKSVEQ
                     IVGDGIQAKISQMTEDCQMKLQDTLQKIINDSSGGMICIII"
     gene            8198..9805
                     /locus_tag="ACZPCR_10160"
     CDS             8198..9805
                     /locus_tag="ACZPCR_10160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase RNA specificity
                     domain-containing protein"
                     /protein_id="HIR1231272.1"
                     /translation="MKLMFIGAAHEVTGSCHYLEACGLKILIDCGMEQGSNKYENAEL
                     PVSYGDIDYVLVTHSHIDHVGLLPLIFARGFSGQVMASRATCDLCNIMLKDCAHIQES
                     EAEWKNRKAKRAGRPQEPPLYTMADAEGVLKHFVPCSYNEIIRLADGVEIRFTDAGHL
                     LGSAFIEVWLTEDGCSKKIVFSGDIGNLNKPLIRNPQYIAQADYVVMESTYGDRFHKH
                     SAEHIEEFARVIQETLDRGGNVVIPAFAVGRTQEVLYYIRRIKEEGLVTGHGDFEVYV
                     DSPLAVEATQVFKNNMLDCYNDETKALVKKGVNPISFKGLKLSVSSEDSVAINFDAKP
                     KVIISAAGMCDAGRIRHHLKHNLWRPECTILFAGYQAVGTLGRSIIEGKKEVKLFGET
                     IDVEAHIEKIEGISGHADQDGLIRFITSFMDKPRQVFVVHGDDDVCDSFAGKLSKEYG
                     ISAFAPFSGTVYNLAEEKFEVITKGIPIRREDEKDASKRAGGVFARLLAAADRLRRVV
                     MHNEGGANKDLAKFADQINSLCDKWDR"
     gene            9835..10311
                     /gene="rnhA"
                     /locus_tag="ACZPCR_10165"
     CDS             9835..10311
                     /gene="rnhA"
                     /locus_tag="ACZPCR_10165"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008976053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI"
                     /protein_id="HIR1231273.1"
                     /translation="MKVEIYTDGAARGNPDGPGGFGTVLHYTDGKGQLHVKELSAGYR
                     RTTNNRMELMAAIAGLEALNRPCQVELYSDSKYLVDAFNKHWLDGWIKKGWKRGKNEP
                     VKNVDLWKRLLEAVKPHQIVFIWVKGHNGHPENERCDFLATSAADGDNLLEDPGVL"
     gene            10460..11527
                     /locus_tag="ACZPCR_10170"
     CDS             10460..11527
                     /locus_tag="ACZPCR_10170"
                     /inference="COORDINATES: protein motif:HMM:NF018684.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme inhibitor LprI family protein"
                     /protein_id="HIR1231274.1"
                     /translation="MKKREFIAAICFICIFGMLVTVQVKRFVSSPSQRADVQEYTASK
                     EYELKRTDQTGPVLKDGAEAAGIREEAGAEQEQDGSNTSPRIEPEYPEGRARGRAASG
                     REAAAVPEPEELKEEAADTSSPKNVSPSESALAESAAEADPLEDSGTAKTAADDTGNE
                     TLKAAGGTVQSRGAAAAETAPDTPAPAQELQRSSRGAASADLISPASETTAVSETAAE
                     KEEQATAQAYQRELDSAAASIKKLKSAETDTSTWSYLNLADYELKLWDDLLNRIYQDI
                     IEHMDETEAEELRKEEKAWIKKRDADAKKVSSRYSGGTLEGLEHTASLAKSTKERAYE
                     LLEDYGSYLPQEEVSGESGEK"
     gene            11697..14303
                     /gene="alaS"
                     /locus_tag="ACZPCR_10175"
     CDS             11697..14303
                     /gene="alaS"
                     /locus_tag="ACZPCR_10175"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016438975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HIR1231275.1"
                     /translation="MFLEFFESKGHLAMKSFSLVPHNDNSLLLINSGMAPLKPYFTGQ
                     EIPPRNRVTTCQKCIRTGDIENIGKTARHGTFFEMLGNFSFGDYFKTEAIHWSWEFLT
                     EVVGLDPDRLYPSIFQDDDEAFEIWNKEMGIPAERIFRFGREDNFWEHGAGPCGPCSE
                     IYYDRGEKYGCGKPGCTVGCECDRYIEVWNNVFSQFNNDGHGNYTELEHKNIDTGMGL
                     ERLAVIVQDVDSLFTIDTNKALLDRVCALAGKEYQKDHDTDVSLRIVTDHIKSCTFMI
                     SDGIMPSNEGRGYVLRRLLRRAARHGRKLGIEGKFLAELCKTVIELSKDGYPELDEKK
                     SMIFKVLTEEEDKFNKAIDQGLSILGEMEAEMAEKGEKVLSGENAFMLYDTYGFPVDL
                     TKEILEEKNLSVDEDGFAACMKKQKETARAARKTTNYMGSDVTVYQSIDPSVTTEFVG
                     YDRLTHQSEITVLTTEDELAEALTDGQNGTIIVKETPFYATMGGQQADIGVIRTEGGE
                     FQVKDTIKLQGGKVGHVGTVTKGMFKVGDQVTLEVNKENRELTGRNHSATHLLHKALR
                     TVLGTHVEQAGSLVTSDRLRFDFTHFSAMTPEEIAKVEKMVNDEIAASLPVVTDIMSL
                     EEAKKTGAMALFGEKYGDSVRVVKMGDFSTELCGGTHVPNTSTISSFKIISEAGIAAG
                     VRRIEALTSTGLMNYYHEMEEELHEAAKLVKTTPAALHDKLQAMLDEIKALHSENEKL
                     KSKLANDSLGDVMNQVKEVNGVKFLAAKVDGVDMNGLRNLGDQLKEKLGEGVVLIASV
                     QDGKVNLMASATDEAQKKGAHAGNLIKAIASLVGGGGGGRPNMAQAGGKNPAGVEEAL
                     KKAEEVIASQIQ"
BASE COUNT         4016 a         3079 c         4086 g         3336 t
ORIGIN      
        1 ccttcaacgt catcaccggc ttctaccgcc ccaccgaggg cgacgtggtc ttcgcgggcc
       61 gcaggatcac cggcatggct ccgcaccgca tatgctccct cggcatggcc agaacctttc
      121 agaacatccg tctgtttaaa gatctgagcg tccttgacaa tgtaaaggtg ggacttcaca
      181 accaccattc ctacagcact cttgcaggta ttttccgtct gccgaaatac aggaaggtgg
      241 agcgggagat ggacgagcgg gctctggagc ttttaaaggt atttgacctg gaaaaagaat
      301 tcgcagtaaa agcttccaac cttccctatg gaaagcagag aaagctggag attgccagag
      361 cgcttgccac agagccgaag ctccttctct tagacgagcc ggctgccggc atgaatccca
      421 acgagacgaa ggaactgatg gataccattc agtttgtccg ggataatttc gatatgacga
      481 ttcttttaat tgagcatgat atgaagctgg tatccggaat ctgtgaaaag ctgactgtgt
      541 taaacttcgg ccacgtgctg acagagggac cgaccagcca ggtgctgaat aatccagagg
      601 ttgtgaaggc atatttggga gagtaggcag gctgcatatc agaaaataaa tttgtggaaa
      661 gcgggaggtc agagtcatgg caatgctgga agtaaaggat ttaagcgtct attacggcgt
      721 gatccaggcg ctcaagggta tctccttcga ggtagaggag ggggacgtta ttgccctcat
      781 cggagccaac ggagccggaa agacgacaac ccttcatgcg cttacaggcc tgattccggt
      841 gaaatcggga agtattgtat ttgagggaaa agatatcaca aaggttcccg gctataagct
      901 ggtatccatg ggaattgccc atgtgccgga gggacgccgg gtattcgccc agctgacggt
      961 tcttcagaac ctgaagatgg gagcgtatac aagaaacaat aaacaggaga gcgaggaaac
     1021 gattcagaaa atatataagc gttttccaag actggaggag aggaaaaacc agctggcagg
     1081 aaccctctcc ggcggcgagc agcagatgct ggccatggga cgggcgctga tgtcccaccc
     1141 caggctgatt gttatggacg agccgtccat gggtctttct cctttgtatg taaacgagat
     1201 ctttgagatt atcaaggaga tcagcgccga gggaaccacg gttctcctgg tggagcagaa
     1261 cgctaagaag gccctttcca tcgccaacaa ggcgtacgtg ctggagacgg gaaaaattgt
     1321 gctcagagga gacgccaagg agctgatgaa caatgatcag gtgaaaaaag cgtatttgag
     1381 cgagtaggaa aaatattaaa agtaagaagc aggagctgtt tggtgatttt atggagcacc
     1441 agtcaggttc ctgctttttg ttttgggaga gagaagaatt ttgaagtctt atgaattatc
     1501 tatatattga taatatctat ccatatattt tcttatagac aataataatt atacatttat
     1561 tacaaaatat ggtataagat aggtgtttgt ttttataata gttcaacaat aagggggtgt
     1621 aatgatggat attataaaag aagaggctat gaagaagctg aatgccagcg aacttctgac
     1681 caggaaacct gtcggaatta aatttttatt tacaaaagag gattacgagg cttgcacggc
     1741 agaacctgcc aaagctaaaa tggcctactg tgtgatggta aaaattgcca gcatgggagt
     1801 ttcgctgaaa acagatattg aaatgtgcag ctgcggagga ggaacacggg cattgggatt
     1861 ggaagagccg tcagaaaggt attacactgg atgtgaagcc tattctttcg ggttgtatcg
     1921 cgatttagcc gttgccaaac aggaagtcaa cagcctgaca ttttgcagac atcataccta
     1981 tggacttctg atacagcctt tggaagccta tgaagtctat gatccggatg tggtgattct
     2041 gttttctgat tcttttggga cgatgcgctt aatacaggga tatacatatc actatgggcc
     2101 gcagtctaat tttaagatga caggaaatca ggctttgtgc tctgaatgta ccgcataccc
     2161 gtatgaaatg aattctatga atatttctat gttctgctcc ggtacacgtt atctggcagg
     2221 atgggataat tcagagattg gaatcggtat gccgtacggg atttttacag gagtctgcga
     2281 cggtatctac cgaagcgcca acggagtgga gagagattgc agaaaagctg tgctgcgtgc
     2341 aaatctgaag gaggccggtc tgaaagatcc agggctggtg gacggacagg cctattatat
     2401 gatgcagaag tagtgggagg agcggtgtta tgaaacagaa agcagcgctg tcagccctgg
     2461 ctgtccgtat ctttttaatt ctctctgtac tggcactctg ggaatggggg gtgagaagca
     2521 gccggctgcc ggacttttac atcagctatc cttcggaaat tgcgatggat ttatgggatt
     2581 ttattaccag cggggaactg tggaagcatg cttccgtgac tcttcaggaa gctttcgcag
     2641 gtctgtttgg aggaagtata gctgggattg cagcgggaat tctgctggga cagtttccat
     2701 ttttggggag aatttttaaa ccgattatta ctgcagtcca tgggattccc cagctgacct
     2761 tggctccggt gtatattctc tggtttggaa tcgggatgca gtcaaagatt ttcctggcag
     2821 gtctgagcgc atttttctgc gtattttttt caacctatgg agcaatcttt gatatggaac
     2881 ctaagctgat tgaatctgcc agccttctgg gagctaaaaa gacgcagatt ttatggatgg
     2941 tagtgcttcc cacctgtacg ccatggatct tatcgggaat ccgttctggc ttcagcgcca
     3001 gtctgattgg agcgatagtg ggagaatata tgggtgccgg agcgggcttt ggatggatgg
     3061 ttgcctatgc aacttcgtat tttaacatga aacgtgtgat gtcatgtatt tttattctgc
     3121 tgctgttggg gctggtttta aattttggtc tggacagagt ggaagaggcg cttctcaaat
     3181 ggaggccaag agcttcttta aatattgggg aggagaagga acaaaacgat cattaaaaaa
     3241 aataaaatgg ggaaaggaac gattgaacaa tgagaaagtg gatatctttg atgtgtgccg
     3301 ccggcattgc ggcagcagct cttatgggat gctcgggagc ggagacagct ggaaagaacg
     3361 aaacaaaagc ggccgcagaa gctgcggctg gggagtcagc agaaagtctg agcagtgaag
     3421 agacaaaaaa ggaagaagat aagaaagagc tcacaaagat tgtcgtttca gaattccgcg
     3481 gcatctgctg ggcatccgcc tatgcggcag agcagctggg atattttgag gaagagggac
     3541 tggacgtaga gtttatgctc tacaaagacg ggcccattgc attccaggga atgcatgcag
     3601 gagattcgga tttctgcctg ctttccgctg agccggtaat gactgcctat gacgagggaa
     3661 tggaatctta tctgctttta accaacacga accgccgtac ctatgcgttt gcaggagcag
     3721 cagatattaa aacagcagcg gacttaaaag gcaagacaat ctttgcagga atgcctggct
     3781 cagctccata ttcttttgtt ttatccatgc ttaaaagcgc cggactgagt gaaaatgatg
     3841 taaactttat taatcttgat tatggctcgg ccatcgttgc tttgggagag aagcaggtag
     3901 atggaatttt ctttgacgtc tacaataagg cgattttaga ggagacagtt ccggatgcta
     3961 acattctgtt agactgcaca gatacacaaa cccatgaagc gctttatggt tctcagttct
     4021 gccagaccag cattgttact tgtacaaaga agtttgcaga agagaatcca gagaccgtgc
     4081 aggcgtttgt aaacgcttct tccagagctt taaaatggat tagcgagcac acctctaagg
     4141 aactggcaga gctgatttcc cctatgtacg acagtatgac agtagatgaa ttgactgcca
     4201 agtttgagtg cattaaggat acgttttctg agacgggaga aattattccg gaaggatatg
     4261 agacgatgga gagcttctgc cttgatcagg gacttattga gaacagcatc ccatatgagg
     4321 atattgtagc ttctgatttt atggatgcgg caatagaaaa ataagacaag gcagacgtga
     4381 ggagtgcagg agggaaaatg gcttatatct catttgaaca gattgaaaaa tactatggtt
     4441 ctcagcatgt actgaaaaat ctcagtctgt ctgtggataa gggggaattt gttacgcttc
     4501 ttggtccctc cggatgcgga aaaagtacgc tgcttcgctg cctggctggt ttggaatcga
     4561 tttcctctgg acgcatttta ctggatgggg aggagattac ccatgttcct ccgcgccaga
     4621 ggaacgtcgg aatgattttc cagcagtaca gcctgtttcc gactatgaat gtatacaata
     4681 atatcgcttt tggactgaaa atacagggag tatcgaagga ggaagctagg ctccgcattg
     4741 cagaagcatt aaaaatggca gatctagcag gcagcgagaa taaatatcca tctcagctgt
     4801 caggaggaga gcagcagaga gtggcccttt gccggtgtat tgtaacaaag cccaaggtac
     4861 ttttaatgga cgagcctttc agcgctattg acgcaaagct tagaaaagct cttcagaaga
     4921 gaatcaagga gattcaccgt gaactgggga tgaccacgat ttttgttact catgatcagg
     4981 acgaggctat gtccatgtcg gatacgattc acctgatgaa tcgaggaatt gtagagcagt
     5041 cggcaaggcc tctggaactg tatgcgcatc ctaagacagc ctttgccgcc agcttcatgg
     5101 gcaattataa catgatgacg gcggagcagt ttcggtctgt gacaggagac cagtggaggc
     5161 gggatgtgtg tattcgtcct gagctgattg agattttcgg agattctgtg gaagatttag
     5221 agcagagaaa agagggatat actctatctg ggacagtaac agaaagaatt ccgcagggaa
     5281 atacggtgct gtattatgtg acagtatctg atctgcagtt taaggtatcc aggctattta
     5341 atagccctgc attttttgaa gaggggcaga aggtatgtct gttcattccc agggatgcgg
     5401 tactgcagta tgagaaagaa acgtaattga cggtttggga gcctgcggta aaacgacaga
     5461 gggataaaca tgttttccag tgactttaac tggagcaagg aaaacatgtt tatccctcta
     5521 tttatgatcc tttaaattct aaaccacccg gcaaaagcgg ctccttccgg aagctcataa
     5581 ctcttctcag gagtgcccag ctgccatctg ccaggatgtc ccgtgttctg ggagagaacc
     5641 tcggcgaagt ggagcattac gatacccgcg ttcagctttg cgtgctctgg ggaggtcatt
     5701 tcatcctcta aaagaaccag agataccaca tcgtgatcca gaatgaagcg gtaaggctgg
     5761 cggtttaata cagacgggga gcagcaggct gcgatgaaag cgcggtacag atcagaatcc
     5821 ggctcccagt cggctaaatc agatttctgt ccccatgctc cgccgaatac agcgtcctcc
     5881 agatagagct tcggagcaat ctggccgttg cgctgtttca tgtggacgga tgccgggctc
     5941 ttgatatcca gacgggttcc gccttccggc tttccgtatc caaaagcgat cagagccagt
     6001 ggctccagtt ctgtgtcaag gtgaaggcgc tgctttaaca gagcgggatc tgtaatcgta
     6061 atccagcagg agtccagatc cagctctgtc agcttcagaa ccatgtcttc gcccatatat
     6121 ccggcatttt ccagggcgcc gtcttcctgt cctgacagaa gaagcaggta agagggagcc
     6181 tctatcatga agccagagta gccggctgtt ccggacaggt ttccaggatt tccctccaga
     6241 accttccact ctgccggaag tccgggaaga aggcgtttgc actgtccggc gtaatcctta
     6301 atctggttca gcgtctgggc agcgaccttt ttatctttaa agtctctcgt tgatttgcgc
     6361 ttaatggcaa gctcgtagta tttcatagac accatccttt cgtgcgacaa ttctcgattg
     6421 tctgaattaa ttgtataaaa tcgcggaaaa ggtgtcaagt gattttattg atacgcctgc
     6481 tgcgcctgac gggaagaatc gagtttccca tgtctagctt gaaatgtgcc tgcatatact
     6541 gtaccagcac agcaaggggg tcattttatg gaaaatttta acgtatacag agacattaag
     6601 gccagaacag acggggaaat ctacataggc gtggtgggac cagtgagaac cgggaaatct
     6661 acgtttatca aacggtttat ggagcagatg gtgcttccgg agatggagga tggccatgcc
     6721 aaggagcggg ccagagacga gctgccccag agcgcggcgg gaaaaacgat tatgacgaca
     6781 gaaccgaaat ttattccaaa ggaggcagtg gaaatcccat tgggggacgg agtggaggca
     6841 aaaatacgct tgattgactg cgtgggattt atggtggacg gtgcggcggg acatattgaa
     6901 aacgatacgg agcgccttgt aaaaacgcca tggtttgact atgaaatccc atttacacag
     6961 gcagcggagc tgggaacgag gaaagtgatt accgatcact ccaccatcgg ccttgtgatc
     7021 acggcagacg gttcctttgg agagattaaa cgtccaagct acatggaagc agaggagaaa
     7081 acggtgaggg aactgaaagc gctgggaaag cctttcctga ttcttttaaa ctccatgcgc
     7141 ccctattcag atgagacaaa ggtcctggct ggacagatgg aggaaaaata cggcgtccag
     7201 gtaatgcccg taaactgcga gcagctgaaa aaggaggata tccggcgcat tatggaaacc
     7261 gtgctgacag agtttccggt agcagaaatg gatttcttta ttcctaaatg gctggaaatt
     7321 cttccgcagg agcactggct gaaaatacat gtggtgcagg cagtgaaaga gctaatgaag
     7381 aaaatcagcc gtatgaagga cattggggga gaacttccag ttccttccga cggcccaatc
     7441 cggcggatta agatcagggg aatgaaaatg gcggacggaa gcgtatctgt ggatatcgag
     7501 gtggacgaca gctgctatta ccagatttta agcgattaca cgggagtgga gatcggcgga
     7561 gaatatcagc tgatgcagac gctgaaacgg ctggcagcta tggaacggga atatgaaaag
     7621 gtgggggacg ctttgagcca ggtgagactg aaaggatatg gagtggtgac gccggaccgg
     7681 tcagagattg tcctggatga gccgcagctg attcaccacg gaaataaata cggcgtcaaa
     7741 atgaaagccc aggctccgtc aattaatctg attaaagccc acatagagac agaaattgcc
     7801 cccattgtgg gaagcgagca gcaggcggag gatttaatag aatatatcaa agccaacgcc
     7861 aaggagagcg aggacggact gtggaacacc aacatttttg gaaaaagcgt agagcagatc
     7921 gtgggcgacg gaatccaggc aaaaatctcc cagatgaccg aagactgcca gatgaaactt
     7981 caggacaccc tgcagaagat catcaatgac agcagcggcg gaatgatttg cataatcatt
     8041 taagactatg gtataatgta ccacatcaga aagaaaacaa gcgtctgctg cgcagacatt
     8101 tgttttctct gatgtggtat cgacaaaatg attgagctgt cgaagacagc gccggatgtg
     8161 cgggggcaca gccgcatttt ggaaaggaga gggttatatg aagctgatgt tcattggggc
     8221 ggcccacgag gttacgggaa gttgccatta tctcgaggcc tgcggtctta agatcctgat
     8281 tgactgcgga atggagcagg gctctaacaa atatgaaaac gcagagctgc cggtcagcta
     8341 cggggacatt gactatgtgc ttgtcactca ttcccacatt gaccatgtgg ggcttctgcc
     8401 tcttattttt gcgagaggct tttccggaca ggttatggcg tcccgggcca cctgcgacct
     8461 ctgcaatatt atgctgaagg actgcgccca tattcaggag tcggaggcag agtggaagaa
     8521 cagaaaagcc aagagagcag gacggcctca ggaaccgcct ctctatacca tggcagatgc
     8581 agaaggggtg ctgaaacatt tcgtgccgtg cagctacaat gaaattatcc gtctggcgga
     8641 tggggtggaa atccggttta cggatgcagg ccatcttttg ggctctgcct ttatcgaagt
     8701 gtggctgaca gaggacggct gttcaaagaa aatcgtattt tccggcgata ttggaaatct
     8761 caataaaccg ctgatccgta atccgcagta tattgcccag gcagattatg tggtgatgga
     8821 atctacctat ggagaccgct ttcacaagca ttcggccgag catatcgagg agtttgccag
     8881 ggtgatccag gaaactctgg atcgaggcgg caacgtggtg attccagcct ttgccgtagg
     8941 ccgtacccag gaggtgctct actacatccg ccgaatcaag gaggagggcc ttgtaacagg
     9001 ccacggagat tttgaggtgt atgtggacag ccctctggct gtggaagcta cccaggtatt
     9061 taaaaacaat atgttggact gctacaacga cgagaccaag gcccttgtaa aaaagggagt
     9121 aaatcccatt tcctttaaag gcctgaagct ttccgtcagc agcgaagact cggttgccat
     9181 taactttgat gcaaagccta aggttattat ttcagctgca ggcatgtgcg acgccggccg
     9241 tatccgccat catctgaagc acaatctctg gagaccggaa tgcaccattc tgtttgccgg
     9301 ttaccaggcg gtgggaactc tcggaagaag catcatcgag ggcaagaaag aggtgaagct
     9361 gttcggcgag actattgatg tggaggcgca catcgagaag atagagggca tcagcggcca
     9421 tgcggatcag gacggcctga tccgttttat cacaagcttt atggataagc ccaggcaggt
     9481 gttcgtcgta cacggcgacg acgacgtctg cgattctttt gctggaaagc tcagcaaaga
     9541 gtatggcatt tctgcctttg cgcctttcag cggaacggtc tataatctgg cagaagaaaa
     9601 atttgaggtt attaccaagg gaattccgat ccgccgcgag gatgaaaagg acgcttccaa
     9661 gagagccgga ggagtcttcg caagacttct ggcagcagcg gaccgcctcc gcagagtcgt
     9721 tatgcataac gagggaggcg ctaataagga tctggccaag tttgccgatc agattaattc
     9781 cctctgcgat aaatgggatc ggtaacagaa tacaggatag aaggagacag acagttgaaa
     9841 gtagagattt acacagacgg agcagcccgg ggaaacccag acggcccagg cggttttgga
     9901 acggtgcttc attatacaga tggaaaggga cagctccatg tgaaggagct ttcagccggt
     9961 tacaggagga ccaccaacaa caggatggaa ctgatggcgg ctattgcagg gctggaggcg
    10021 ttaaaccgcc cctgccaggt ggagctgtac tcggactcca aatatctggt agacgctttt
    10081 aacaagcatt ggctggacgg ctggattaag aaaggctgga agcgggggaa aaatgaaccg
    10141 gtgaaaaatg tagatctgtg gaaacgcctg ctggaagctg taaagcctca tcagattgta
    10201 tttatctggg tcaagggcca taatggacac ccggaaaacg agcgctgtga ttttctggct
    10261 acatctgcgg cagatggaga taacctgctg gaggatccgg gagttttata gcttcaactt
    10321 ctgacaaaaa caggaaaata ttaaggttcc cttacaaaat attacgtctt tcttctgccg
    10381 ctttcttttc gcggaaaagt atggtatgtt attgatatga tattgaatgt atcagaaata
    10441 tactaaagga tgggtcagtt tgaaaaagag ggaatttatt gccgccatat gttttatctg
    10501 catatttgga atgctggtga cggttcaggt gaagcgtttt gtatccagcc cttcccagag
    10561 agcagacgtg caggagtata cggcgtcaaa ggagtatgaa ctgaaaagaa cagatcagac
    10621 ggggcctgtc ctgaaagatg gggcagaggc ggctggcata cgggaagaag caggagcaga
    10681 gcaggaacag gacggctcta atacctcccc ccgtatcgag ccggaatacc ctgagggcag
    10741 agcgcgcggg agggctgcct ccggcaggga ggcggctgct gtaccagaac cggaggaact
    10801 gaaagaggag gcggcagaca cttcttctcc gaagaatgtt tctcccagtg aatctgcctt
    10861 ggcagagagc gcagcagaag cagaccctct ggaagacagc gggacggcca agacagctgc
    10921 ggacgatacg ggaaacgaaa ccttaaaggc cgccggcggg acggtgcaaa gccgtggggc
    10981 ggctgcggca gagacagcgc cagatacgcc tgctcctgcg caggaacttc agcgatccag
    11041 ccgtggggcg gcttccgccg atttgatttc tccggcttca gagacaacgg ctgtgtcaga
    11101 gacagcagct gaaaaggaag agcaggccac tgcccaggcg tatcagagag agcttgacag
    11161 cgcggcggct tctattaaaa agctgaaaag cgctgaaacg gacaccagta cctggtctta
    11221 tctgaatctg gcggattatg agctgaagct gtgggacgat ctgctgaacc ggatttatca
    11281 ggatattatc gagcatatgg acgagacgga ggctgaagaa ctcagaaaag aggaaaaggc
    11341 gtggattaaa aaacgcgacg cagacgccaa gaaggtgtcc tcccgctaca gcggaggaac
    11401 gctggaagga ctggaacaca ccgcttccct ggcgaaatcc acaaaggaac gggcctacga
    11461 gctgctggag gattacggca gctatctgcc tcaggaggag gtttccgggg aatccggaga
    11521 aaaatagaat aagcagacag aaaaaggcgg agattttctt cgccttttcc cggtcaaaaa
    11581 ccttgaaaat cgcatattcc tgtgatagga tatacgaatg aataaaaata ttacttactt
    11641 tatgtaaggc aggaggaaac aacgtggaaa aatacggtgt aaacgaactg agaaagatgt
    11701 tcctggaatt ttttgagagc aagggacatc tggcgatgaa gagcttttct ctggttccgc
    11761 ataatgataa cagcttgctg ctcattaatt ccggtatggc tcctttaaag ccgtacttta
    11821 caggccagga aattccgccg agaaatcgcg tgaccacatg tcagaaatgt atccgtaccg
    11881 gcgatattga gaatatcgga aagacagccc gccacggcac attttttgag atgcttggaa
    11941 acttctcctt tggagattat ttcaaaacag aagcgatcca ctggtcctgg gagttcttaa
    12001 cagaggtagt gggtctggat ccggatcgtc tctatccgtc tattttccag gacgacgacg
    12061 aggcgttcga gatctggaac aaggagatgg gaattccggc agagcgtatt ttccgtttcg
    12121 gaagagagga taacttctgg gagcacggcg caggcccctg cggtccctgt tctgagattt
    12181 actatgaccg cggcgagaaa tatggctgcg gaaagccggg atgtacagta ggctgcgagt
    12241 gcgaccgcta catcgaggtg tggaacaacg tgttctccca gtttaataac gacggacacg
    12301 gaaattacac agagctggaa cacaaaaata tcgatacggg catgggcctg gagcgtctgg
    12361 ctgttattgt gcaggatgtg gattctcttt tcacaattga cacgaacaag gctcttcttg
    12421 accgtgtatg cgctctggca ggaaaggaat accagaagga tcacgacaca gacgtatctc
    12481 ttcgtatcgt gacagatcat atcaagtcct gtacgttcat gatctccgac ggcatcatgc
    12541 cttccaacga gggacgggga tacgtgctca gaagactgtt aagacgtgct gcccgccacg
    12601 gcagaaagct gggtatcgag ggcaagttcc tggcagagct ctgcaagact gtcatcgagc
    12661 tttccaagga cggatatccg gagttagacg agaagaagtc catgattttc aaggttctca
    12721 cagaggaaga ggacaagttc aacaaggcca ttgaccaggg actttccatc ctgggcgaga
    12781 tggaggccga gatggcagag aagggcgaga aggtactctc cggcgagaat gcgtttatgc
    12841 tctacgatac ttacggcttc ccggttgacc tgaccaagga gatcttggag gagaagaatc
    12901 tttctgtaga cgaggacggt ttcgccgcct gcatgaaaaa gcagaaagag acagccagag
    12961 cggccagaaa gacgaccaac tacatgggat ccgatgtgac cgtttaccag tccatcgatc
    13021 cgtctgtcac cacagagttc gtaggctacg acagactgac tcaccagtct gagattacgg
    13081 ttctcactac agaggacgag ctggcagagg ccctcacaga cggccagaac ggaacgatta
    13141 tcgtaaagga aactcctttc tacgctacca tgggcggcca gcaggcagat atcggcgtga
    13201 tccgcacaga gggcggcgag ttccaggtaa aggataccat taagcttcag ggcggcaagg
    13261 taggccatgt gggaactgtc acaaagggca tgttcaaggt cggagatcag gtgactctcg
    13321 aggtaaataa ggaaaaccgc gagctgacag gcagaaacca ctctgctacc cacctgcttc
    13381 acaaagctct gcgcacggtt ctgggaacgc atgtagagca ggctggttcc cttgtgacaa
    13441 gcgacagact ccgctttgac tttacccatt tctctgccat gactccagag gagattgcaa
    13501 aggtagagaa gatggtaaac gatgagatcg ctgcgtctct tccggttgtg acagacatta
    13561 tgagtctgga agaggccaag aagacaggag ctatggcgct ctttggcgag aagtacggcg
    13621 acagtgtccg cgtagtaaag atgggagatt tctccacaga gctctgcggc ggaacccatg
    13681 ttccgaatac cagcacgatt tcttccttca agatcatttc cgaggccgga attgcagcag
    13741 gcgtgagacg tatcgaggct cttaccagca caggtctcat gaactactac cacgagatgg
    13801 aggaggagct ccacgaggct gccaagcttg tgaagacaac tccggctgcc ctgcacgata
    13861 agcttcaggc tatgctggac gagatcaagg cgcttcattc tgagaacgag aagttaaaga
    13921 gcaagctggc caacgattct ctgggcgacg taatgaacca ggtaaaagaa gtaaacggcg
    13981 tgaaattcct ggccgctaag gtagacggcg tggatatgaa cggtctgaga aatctgggcg
    14041 accagttaaa agagaagctg ggagagggcg tagttctcat tgcctctgta caggacggca
    14101 aggtaaacct gatggcttcc gcaacagacg aggctcagaa gaaaggcgct catgccggaa
    14161 acctgatcaa ggcgattgct tccttagttg gcggcggcgg cggcggacgt ccgaacatgg
    14221 cccaggccgg cggaaagaat ccggcgggag tggaggaagc tctgaagaag gcagaagagg
    14281 tcatcgcttc ccagattcag taaacggttt ggaacagaag accgacgaaa aaaataaaaa
    14341 aaattcaaaa aacataaaaa tcctgttgac gaatatggga tttgtggtat aatcataaca
    14401 gtgctaaaaa aatgcccaaa cagttgtatt aatatgcact tattacacaa ctgaagggag
    14461 gttaggtgtg agctatgtca aatgtaatcg ttaaagataa cgaaagttta gacagcg
//
LOCUS       DBMDUW010000061        14487 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_2273_length_14487_cov_4.521132, whole genome shotgun sequence.
ACCESSION   DBMDUW010000061 DBMDUW010000000
VERSION     DBMDUW010000061.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 14487)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 14487)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14487
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2273_length_14487_cov_4.521132"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(103..2013)
                     /locus_tag="ACZPCR_10180"
     CDS             complement(103..2013)
                     /locus_tag="ACZPCR_10180"
                     /inference="COORDINATES: protein motif:HMM:NF039407.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6320 domain-containing protein"
                     /protein_id="HIR1231276.1"
                     /translation="MKRWKDRKRVQGAGWRRLDNTGKLFAMVTGEDLSNVFRVSAVLA
                     EEVDGARLQEALKQTLPDFQVFQVKLRRGFFWNYFESNTREPEVELETPYPCRFIEPH
                     SSQMYLFRVSFFKKRINFEVFHGLTDGMGAMNFLKRLVEHYLILGETAGPEKEKAGSQ
                     EEKDRQETFQREAGYSDDGYLFHYDQGRKGTNTGYEKQRAFQLKGKNLPFGETAVFHG
                     YLDLKKFKALCREKKVSMTKYLAALLLWSLIQVYLDGETKKEPVAVNLPINLRAFFKS
                     DTMANFFAVTNISFPAHRRPASFDEVLSEVSRQMDEKIVRERLEETIASNVSQEKKWY
                     VRITPLALKHLITGILFAKNTKGYTLTLSNLGPVAVEEPFQEKIEDFHVMIGVSPRQP
                     LKCGVMAFGDTVDLTIASVKADRRFADYVYGWLEQEGILTGREENGAFASEFDRGSYP
                     EMTEEKNRIRKAAPWFYGALLAAAVITGIVNAATYRWLGKWWSVLSIAGIAYAAMTVR
                     FSILRHSSLAGRLVRQSLGACVLLVLIDWFCGYGGWAFNYAIPCVLLFNVVAVGGLIA
                     LNRLNWQVHFMYQIVITLFTMIPLALWWAGLVTKPFLSLFTAGTAFLLLAVTGAVGSR
                     SVKRELGRRFHI"
     gene            complement(2026..2523)
                     /locus_tag="ACZPCR_10185"
     CDS             complement(2026..2523)
                     /locus_tag="ACZPCR_10185"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1231277.1"
                     /translation="MDIKIRTVKPEDLDLVTAVEAECFPAAEAAGRADFERRIKTFPE
                     SFLIAEKAGRIIGFINGCVTDETAICDEMYEDEAFHRENGAYQSVFGLDVIPGERNQG
                     VAELLMRALMERARAARRKGMILTCKDRLIHYYEKFGYVNYGVSGSVHGNVVWYDMRL
                     EFGQR"
     gene            complement(2699..3397)
                     /locus_tag="ACZPCR_10190"
     CDS             complement(2699..3397)
                     /locus_tag="ACZPCR_10190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003505142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIR1231278.1"
                     /translation="MAKVLVVDDEKLIVKGIRFSLEQDGMEVDCAYDGEEAVQMAREK
                     EYDMVLLDVMLPKRDGFEVCQAIREFSEMPIIMLTAKGGDMDKILGLEYGADDYVTKP
                     FNILELKARIKAIMRRNTRRMKKEEKPGSRVISAGDLKLDTDSRRVFIADREINLTAK
                     EFDLLELFVCHPNKVYSREELLGYVWGNKAAAGGDVRTVDVHVRRLREKIEPSPSDPK
                     YVHTKWGVGYYFRA"
     gene            complement(3421..4176)
                     /locus_tag="ACZPCR_10195"
     CDS             complement(3421..4176)
                     /locus_tag="ACZPCR_10195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HIR1231279.1"
                     /translation="MKKEKAAGWAKAVAALACMIAAGLCYSCSRMDGEGPGSQTGTRI
                     VIGEESRERVSGTPEAEETLEKEKNLTAEERSEAETSGVPSAEQTQEPEEFIYVHVCG
                     QVVSPGVYQLLKGSRVYEAVAMAGGCTEQGAPDCLNMAQELTDGMKIQVPDQETARRI
                     LEEQASGTGVINPSGTGPDSPGTSGEGEALVNINTASREQLTTLPGIGESRAEDIIRY
                     REEYGDFQKIEDIMKVSGIKEAAFQKIKDRITV"
     gene            complement(4272..4706)
                     /locus_tag="ACZPCR_10200"
     CDS             complement(4272..4706)
                     /locus_tag="ACZPCR_10200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018593754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HIR1231280.1"
                     /translation="MWGTITALVSGALMSIQGVFNTEVTKQTGTWVASGWVQASAFLT
                     CAVFWLFSGRERIGGLLQVEPKYMLAGGVIGAFITYTVIKSMGALGPARAALLIVVSQ
                     ILVAYGIEVLGLFGVAKAGFQWRKAIGAAVAVAGIIIFRWES"
     gene            complement(4776..5519)
                     /locus_tag="ACZPCR_10205"
     CDS             complement(4776..5519)
                     /locus_tag="ACZPCR_10205"
                     /inference="COORDINATES: protein motif:HMM:NF016300.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIMPL domain-containing protein"
                     /protein_id="HIR1231281.1"
                     /translation="MKRRGLVLSAVLAGALMTTACAAQTGTGTAAAGDVQQKVVNVTA
                     SETVTAEPDIAEFEMTVYSQATDAKTCQTQNSTDLEKAVEALKSQGIAETSIQTASFG
                     LNPIYDWEAGKTITGYEMETRLTVKDVPIEKAGDVLSTVVDAGVNRIDSVSYLCSSFD
                     EKYEEALKLAIENGKKKAASMAEAGGCSIGQTISISELSSDQSARYTEPKAIALETAS
                     ADMAAGMGANVMGGEIEIEASVSIDFAIK"
     gene            complement(5681..6526)
                     /locus_tag="ACZPCR_10210"
     CDS             complement(5681..6526)
                     /locus_tag="ACZPCR_10210"
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003505132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylenetetrahydrofolate
                     dehydrogenase/5,10-methenyltetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HIR1231282.1"
                     /translation="MITLRGAEVSEKLKTQVQESLNGLGRVPRLAIVRVGESPDDISY
                     EKGAVKKMAAFGLEAVKYTFPENIPDQEFKTAFGRINSDPKIDGILVFRPLPEQIVQE
                     DIDRMIDPLKDLDGISPVNIAKVFSGDNTGFAPCTAEAVMDILRFNGISPAGKRAVIV
                     GRSMVVGRPLAMLFLQENATVTVCHTKTVDLPQLCRSADILVVAAGCANMVDKSFVKP
                     GAVVIDVGINVDENGKLCGDVDFKDIQETASMATPVPGGVGSVTTSVLAKRLVHAAQL
                     QNKEA"
     gene            complement(6608..6928)
                     /locus_tag="ACZPCR_10215"
     CDS             complement(6608..6928)
                     /locus_tag="ACZPCR_10215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HIR1231283.1"
                     /translation="MELKRVLICVALMALVTYIPRVLPVTVFRKQIRSRFIRSFLDYT
                     PYAVLGALTFPDVFFSTGHLFSAAGGTAVAIVLGYKGKSLVVVAVAAIAAVYILELLA
                     GAAL"
     gene            complement(6918..7748)
                     /locus_tag="ACZPCR_10220"
     CDS             complement(6918..7748)
                     /locus_tag="ACZPCR_10220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HIR1231284.1"
                     /translation="MDWRREFKKGIKSGLPIGIGYIPVSFTFGFLAVSGGLPIWVAVV
                     ISLTNLTSAGQFAGTNLIFAGAGYLEVALTTFVINIRYMLMSLSLSQKLERKTGTLAR
                     LALAFGITDETFVVGSLKPGTLTAPFMLGLILMPVAGWNLGTLMGGCISTLLPQALQN
                     AMGIALYAMFIALIIPAAKASAHVLCIICIAVAVQCGLNYIPVFSFLSDGFRVIISTV
                     AAAGLGAWLFPGTDDSGETEKIEKIEDAADEAAEETAKETDGKMREKAQETGGDGNGA
                     "
     gene            complement(7756..8052)
                     /locus_tag="ACZPCR_10225"
     CDS             complement(7756..8052)
                     /locus_tag="ACZPCR_10225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009215945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231285.1"
                     /translation="MIMRKDVMPVNFLKKENFTGSDRGMRYRMEKTDGEEKTVLTVTV
                     WPEPYGYDATSEEKKTRKQFDFSEEGIEQGVEWLNKMKRERFSGEGSFGEEKDG"
     gene            8363..9586
                     /locus_tag="ACZPCR_10230"
     CDS             8363..9586
                     /locus_tag="ACZPCR_10230"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002568459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006526 - L-arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HIR1231286.1"
                     /translation="MKEKVILAYSGGLDTTAIIPWLKEHFDYEVICCCIDCGQGEELD
                     GLEERAKLSGASKLYIEDIVDDFCDHYIVPCVQAGAVYENKYLLGTAMARPGIAKKLV
                     EIARKEGASAICHGATGKGNDQIRFELGIKALAPDLKIIAPWRMTDVWTMQSRQEEID
                     YCKAHGIDLPFSADSSYSRDRNLWHISHEGLELEDPAAEPNYDHLLVLGVTPQKAPDE
                     AETVTMTFEKGVPASVNGTPMKVSDIIRTLNELGGKHGIGIADIVENRVVGMKSRGVY
                     ETPGGTILMEAHAQLEELVLDRATMEVKKEMGSKLAQIVYEGKWFTPLREAVQAFVEK
                     TQEYVTGEVSFKLYKGNIIKAGTTSPYSLYSESLASFTTGELYDHHDADGFITLFGLP
                     LKVRAMKMAEAEKNK"
     gene            complement(9658..11373)
                     /gene="recJ"
                     /locus_tag="ACZPCR_10235"
     CDS             complement(9658..11373)
                     /gene="recJ"
                     /locus_tag="ACZPCR_10235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002601467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HIR1231287.1"
                     /translation="MAEQIWMLQTKRADFDGIARQFGIDPVTARVIRNRGIEGRENIE
                     RYLYGDLDSLYSPWLLKDMRPAVDILKRKLKEGQKIRIVGDYDIDGVCSTYILYQALK
                     RLGGNVDYAIPDRIKDGYGINESMIRAAAEDGIDTILTCDNGISAFSQIQTAKEFGMT
                     VIVTDHHEVPADGEREILPPADAVIDPKQRSCSYPFPEICGAVVAYKLVQALYEESGV
                     SREEWLELLEFAAIATVGDVMKLQDENRMIVKYGLKKLGHTKNLGLKKLAEKTNLDLN
                     SITAYHIGFVIGPCLNAGGRLQTAKLALSMLLAKDEETAEELAQELKDLNDMRKDMTE
                     HWTAEAKVLADTQYRNDKVLVIFLPDCHESLAGIIAGRLREYCQKPAIVLTRSEEAVK
                     GSGRSIESYHMFQKLSEVKDLMLKFGGHPMAAGLSLLEENIDEFRRELNERSGLTEED
                     FKAKLWIDVPMPIDYINERLVEELKILEPFGQGNEKPLFAQKQVRIRSCRVIGKNKNV
                     VKLVLEGGSGMPMDGILFTDGIAFEEERAGRTVMDIIYYPEINEYNGNRNLQVVIRNY
                     KFPFA"
     gene            complement(11438..12034)
                     /locus_tag="ACZPCR_10240"
     CDS             complement(11438..12034)
                     /locus_tag="ACZPCR_10240"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HIR1231288.1"
                     /translation="MQYLQITNTFRRQPGSLEPDILEIPCRIVRTSRKTMALQIEEDG
                     QVTVRVPRTATEAQAEEFARRHGEWILKTREKVLQNASWRRSYTEAEKQTGKQRLNRK
                     LEERLPLFASVMGVSYGRVSIRDQRTRWGSCSGKGNLNFNWKLSLVPDEILDYVVVHE
                     LAHRIEMNHSANFWREVEKILPDYRERRMWLKENGGRL"
     gene            complement(11988..12296)
                     /locus_tag="ACZPCR_10245"
     CDS             complement(11988..12296)
                     /locus_tag="ACZPCR_10245"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231289.1"
                     /translation="MKMVTIDMKQMESQKEVCELLKRELDFPDDFEGGLDELYAELLG
                     MEENTCVEMIQPEAGSPLESFGKEMESVMERAAQTVDFREDRMYAVFADYEYIQKTAW
                     "
     gene            complement(12573..12646)
                     /locus_tag="ACZPCR_10250"
     tRNA            complement(12573..12646)
                     /locus_tag="ACZPCR_10250"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12610..12612),aa:Arg,seq:acg)
     gene            complement(12828..13646)
                     /locus_tag="ACZPCR_10255"
     CDS             complement(12828..13646)
                     /locus_tag="ACZPCR_10255"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1231290.1"
                     /translation="MIQKCSREQYSRLTSLFKGWHNTMVLSCLEGEMGDVYSTEEMMS
                     AKLDIGDFCFFGGKANENLLYHKKSEYENQLKILVPQTLEWEGLIEKVYGEKVISYKR
                     YSFKRKEEGFSQKELLRIVNGLDADFTLTNMEECRDLFDEVSRTSWAGDWISQFSGYE
                     DYRKRGIGTVLKYKGELVAGASSYAVYSGGIEIQIDTREDFRNQGLGKICGAALILRC
                     LEQGRYPSWDADNEISAHLACSLGYEQDREYTVYRIQQSYQKDADNRWKEERQR"
     gene            complement(13723..13808)
                     /locus_tag="ACZPCR_10260"
     tRNA            complement(13723..13808)
                     /locus_tag="ACZPCR_10260"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13772..13774),aa:Leu,seq:taa)
     gene            complement(13838..13910)
                     /locus_tag="ACZPCR_10265"
     tRNA            complement(13838..13910)
                     /locus_tag="ACZPCR_10265"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13875..13877),aa:Val,seq:tac)
     gene            complement(13938..14011)
                     /locus_tag="ACZPCR_10270"
     tRNA            complement(13938..14011)
                     /locus_tag="ACZPCR_10270"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13975..13977),aa:Asp,seq:gtc)
     gene            complement(14061..14134)
                     /locus_tag="ACZPCR_10275"
     tRNA            complement(14061..14134)
                     /locus_tag="ACZPCR_10275"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14098..14100),aa:Ile,seq:cat)
     gene            complement(14144..14216)
                     /locus_tag="ACZPCR_10280"
     tRNA            complement(14144..14216)
                     /locus_tag="ACZPCR_10280"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14181..14183),aa:Thr,seq:tgt)
     gene            complement(14225..14296)
                     /locus_tag="ACZPCR_10285"
     tRNA            complement(14225..14296)
                     /locus_tag="ACZPCR_10285"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14261..14263),aa:Glu,seq:ttc)
     gene            complement(14391..14463)
                     /locus_tag="ACZPCR_10290"
     tRNA            complement(14391..14463)
                     /locus_tag="ACZPCR_10290"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14428..14430),aa:Asn,seq:gtt)
BASE COUNT         3287 a         4375 c         2881 g         3944 t
ORIGIN      
        1 ttctcaatat tcaattttta aagcagccac cgaaagatgg cttgtttgtg atgcgattaa
       61 ggaaatggat accccctact tctcattttc aatctttcct ctttaaatat ggaaccgccg
      121 tcccagctcc cgctttacgc ttctggatcc caccgccccg gtaacagcca gaagcagaaa
      181 cgctgttccg gctgtaaaca gcgacagaaa cggctttgtc accagcccgg cccaccacag
      241 cgccagcgga atcatggtaa acagcgtaat cacaatctga tacataaaat gcacctgcca
      301 gttcaggcgg ttcaaggcga tcagtcctcc caccgcgact acattaaaca gcagtacgca
      361 gggaatcgca tagttaaaag cccagcctcc atagccgcag aaccagtcaa tcagaaccag
      421 gagcacgcag gcccccagag actggcggac cagccgtccg gccaggctgg aatgccgcag
      481 aatggagaag cgcaccgtca tggccgcgta ggcgatgcct gcaattgaga gcacagacca
      541 ccattttccc agccaccggt aggtagccgc gttgacgatt cccgtaatga ccgcagcagc
      601 aagaagcgcg ccgtaaaacc agggcgctgc cttcctgatc ctgtttttct cctccgtcat
      661 ctccgggtag cttcccctgt caaactcaga cgcaaacgct ccgttctcct cgcgcccggt
      721 cagaattcct tcctgttcca gccatccgta cacataatct gcaaaacgtc tgtccgcctt
      781 cacgctggca atggtcagat ccaccgtatc cccaaaggcc atcacgccgc atttcagcgg
      841 ctggcgcggc gaaaccccga tcatgacatg aaaatcctct attttctcct gaaacggctc
      901 ttccacagcc accggaccta aattggacaa agtcaatgtg tagcccttcg tatttttcgc
      961 aaacaggatt cctgtgatca ggtgcttgag agccagcggc gtgattcgca cataccactt
     1021 tttctcctgg gacacattgc tggcaatggt ctcctccagg cgttccctga caatcttttc
     1081 atccatctgg cggctgacct ccgaaagcac ctcgtcaaag gaagccggcc ttctgtgggc
     1141 aggaaaagag atattggtca cagcaaaaaa attcgccatc gtatccgatt tgaaaaacgc
     1201 cctcagatta ataggaagat tcactgccac cggctccttt ttcgtctctc cgtccaggta
     1261 tacctgaatc agagaccaca gcagaagagc agccaggtac ttagtcatgc tgaccttttt
     1321 ctcacggcac agggccttga atttcttcaa atccagatag ccgtgaaaaa cagccgtctc
     1381 tccaaagggc agattttttc ctttcagctg aaaggccctc tgcttctcat accctgtatt
     1441 ggttcccttt cttccctgat catagtgaaa cagatagccg tcgtcgctgt atcccgcctc
     1501 cctttgaaac gtctcctgcc tgtctttttc ctcctggctt cctgcttttt ctttctccgg
     1561 gccagccgtt tccccaagaa ttaaataatg ttccaccagg cgtttcagaa aattcatggc
     1621 tcccatgccg tctgtcagcc cgtgaaacac ttcaaaattg attctttttt tgaaaaagct
     1681 gacgcggaac agatacatct gactactgtg gggctctata aaacggcagg gatacggcgt
     1741 ctctagctcc acctcaggct ccctggtatt ggactcaaaa tagttccaga aaaagcccct
     1801 tctcagcttc acctgaaaca cctgaaagtc gggaagcgtc tgcttcagcg cctcctgaag
     1861 cctcgccccg tccacctcct cggccagcac tgcgctgacc cggaagacat tgctcaaatc
     1921 ctctcctgtc accatggcaa acagctttcc cgtgttgtca agacgcctcc agccggctcc
     1981 ctgaacgcgt tttctatcct tccatctctt catttcagcc tctttttagc gctggccaaa
     2041 ctccagacgc atatcatacc acactacgtt tccgtgaacg gatccggaaa ccccataatt
     2101 tacatagcca aacttttcat agtagtggat cagccggtcc ttgcaggtga gaatcatacc
     2161 ctttcttctg gccgctctgg cccgctccat aagcgctctc attaaaagct ccgccactcc
     2221 ctgattacgt tccccgggaa tcacatccag cccgaacacg ctctggtagg ccccgttttc
     2281 cctgtgaaac gcctcatcct catacatttc gtcgcagatg gctgtctcgt ccgtcacgca
     2341 tccattgata aagccgatga ttctgcccgc cttttctgca atgagaaagc tctccggaaa
     2401 cgtcttaatc cgccgctcaa agtctgctct cccagccgcc tccgctgccg gaaagcattc
     2461 tgcctccacc gccgttacca aatccaaatc ctccggtttt actgttctaa tcttaatatc
     2521 catctttttg tgcgtccctc tttttctttg tctttctctc tttttctata tttttctctc
     2581 ttttcttata cgccttctgc catctctttt ccagcgcgct tcctcctcat ttcttctaaa
     2641 gcgcgccaaa agcccggcgt cgccgggctt tcagtctcct ttgggcgggc cgttgttcct
     2701 atgccctgaa ataatatcct acgccccact tcgtatgaac gtacttggga tcgctggggc
     2761 ttggttcaat cttctccctg agacgtctta catggacgtc caccgtcctc acgtccccgc
     2821 ctgctgccgc tttatttccc cagacatagc ccagaagctc ctcgcggctg tagaccttgt
     2881 tgggatggca cacgaacagc tccagcagat caaactcctt ggctgtcagg ttaatctctc
     2941 tgtcagcaat gaaaaccctt ctgctgtctg tatccagctt caaatcgccg gcagaaatca
     3001 cacggcttcc cggcttctct tcctttttca tgcggcgggt atttcgcctc ataatcgcct
     3061 tgattctggc tttcagctcc aaaatattaa atggcttggt cacatagtcg tctgcgccgt
     3121 actccagtcc cagaatcttg tccatgtccc cgcccttggc cgtcagcatg ataatcggca
     3181 tttccgaaaa ttcccggatg gcctggcaga cctcgaagcc gtcccgcttg ggaagcatca
     3241 cgtcaagcag caccatatcg tattccttct ctctggccat ctgaaccgct tcttctccgt
     3301 cgtaagcgca gtctacctcc attccatcct gctccaggct gaaacggatt ccttttacaa
     3361 tcaatttctc atcatctact actaagacct ttgccattct cccacctctt catcacattt
     3421 tcacactgtg attctatctt ttatcttttg aaaggcagct tccttgatcc cggaaacctt
     3481 cataatatcc tctatttttt gaaaatcgcc gtattcctcc cgatagcgga taatatcctc
     3541 tgcccgggat tctccaattc ctggaagggt tgtcagctgc tctctggagg ctgtgttaat
     3601 attcaccaga gcctccccct ccccggatgt gccaggactg tccggaccag ttcctgaggg
     3661 attgatcact ccggttcctg acgcctgttc ttccagaatc cgtctggcag tctcctgatc
     3721 cggcacctgg attttcatgc cgtctgtcag ctcctgggcc atgttcaggc agtccggcgc
     3781 tccctgctct gtgcatcctc ccgccatggc caccgcctcg tatacgcgac ttccttttaa
     3841 aagctggtac acgcccggag aaacgacctg gccgcagacg tggacataga taaattcctc
     3901 cggctcctgc gtctgctctg ccgaaggcac gcctgaagtc tctgcttctg agcgctcttc
     3961 tgccgtcaga tttttctctt tttccagggt ttcctccgct tccggcgtcc cactcaccct
     4021 ttcacggctt tcttccccta tcacaattct ggttcccgtc tggctgcccg ggccttcacc
     4081 gtccatccgg ctgcagctgt agcatagccc ggctgctatc atgcacgcaa gggcagccac
     4141 cgccttcgcc catcctgctg ccttttcttt tttcatatgt atcggtacct cctgtccttc
     4201 tggcagaaga tactgttatg cctgtattcc tattctacct aaaacccatg ttaaacacaa
     4261 gcactaaatc gtcagctttc ccaccggaaa ataataatcc cggcaacagc caccgccgct
     4321 cctatggctt ttctccactg aaaaccggcc tttgccacgc cgaacaggcc cagcacctca
     4381 atcccatagg ccaccagaat ctggctcact acaatcagaa gcgcggctct ggcaggcccc
     4441 agggctccca tgctcttaat caccgtgtag gtaataaacg ctcctatcac gccgccggcc
     4501 agcatatatt taggctccac ctgaagcagt cctccgattc gttccctgcc agaaaacagc
     4561 cagaacaccg cgcaggtcaa aaaggctgac gcctgaaccc agccagaggc aacccatgtg
     4621 ccggtctgct tcgtcacctc cgtgttaaaa acgccctgaa tgctcatcag cgcccctgat
     4681 accagggctg taatcgttcc ccacataata aaaaacctcc atggttcaag atacgcttag
     4741 tatctgtccc catggagatt ttatgcgggc ttttcctatt taattgcaaa atcaatggaa
     4801 acagaggcct caatctcaat ctctccgccc attacattgg cgcccatgcc tgccgccata
     4861 tctgcgctgg cggtctctaa agcaatggcc ttcggctctg tgtatctggc cgactgatcg
     4921 gaactgagtt cgctgatgga aatcgtctga ccaatggagc atccgcctgc ctcggccata
     4981 gaagccgcct tcttctttcc attttcaatc gccagtttca gcgcctcctc atacttttcg
     5041 tcaaaggagc tgcacaggta tgatacagaa tcaatccggt tgactcctgc gtccaccaca
     5101 gtggaaagca cgtctcctgc cttttcaatg ggaacgtcct tcactgtaag ccgcgtctcc
     5161 atctcatatc cggtaatcgt ctttcctgct tcccagtcat aaatcggatt caggccaaag
     5221 ctggctgtct gaatagacgt ctccgcaatt ccctggctct tcagcgcctc caccgctttc
     5281 tcaagatccg tgctgttctg agtctggcat gttttcgcat ctgtggcctg agaataaacc
     5341 gtcatctcaa actctgctat atccggctcc gccgtcaccg tttccgatgc agttacattc
     5401 accaccttct gctggacgtc gcctgcagct gcagtcccgg ttcctgtctg agccgcgcag
     5461 gctgtcgtca tcaatgcccc tgccagtacg gctgataaaa cgagtcctcg tctcttcata
     5521 ctgatccctc ctcctggttt ctgtcctttg tcctttgtct tctgttttct atcttttctc
     5581 gctgttcctt ctttttcttt attatacagg attatacagg aaaatgagac gctttgtttt
     5641 tcttttctct taacgactta tttcaatttt ctgaagcttt ttaagcttcc ttgttctgca
     5701 gctgcgctgc gtgaaccagg cgcttggcca gcacagaggt cgtcacagag cctacgccgc
     5761 ctggcactgg cgtagccatg gacgccgtct cctggatatc cttaaaatct acgtcgccgc
     5821 agagctttcc gttttcgtcc acattgattc ccacatcaat gacaactgca cccggcttga
     5881 caaaactttt gtccaccatg ttggcgcacc cggcggccac caccagaata tcggcgcttc
     5941 tgcacagctg cggcagatcc acggtcttcg tatggcagac tgtcacggta gcgttttcct
     6001 gaagaaacag catagccaga ggtctcccca ccaccatgct tctgcccacg atcacagccc
     6061 tctttccagc cggagaaatt ccgttgaagc gcagaatatc catcaccgcc tcagccgtgc
     6121 atggggcaaa gcccgtgttg tccccgctga aaaccttggc gatattgacc ggggaaatac
     6181 cgtccaaatc ctttagcgga tcaatcatcc tgtcaatgtc ttcctgaaca atctgttccg
     6241 gcagagggcg gaacactaaa attccgtcaa tctttggatc actgttgata cggccaaacg
     6301 ccgtcttaaa ttcctgatcc ggtatgttct ccggaaacgt gtatttcacc gcctccagcc
     6361 caaaagcagc catcttcttg actgccccct tttcatagga aatatcgtcc gggctctctc
     6421 ccacacggac aatcgccagc cttggaacac gtcccaggcc gtttaagctc tcctgaacct
     6481 gtgtcttcag tttttcagaa acctctgctc ctcttaatgt aatcattgtc tcttcctcat
     6541 ttctgccttt gtattctgtc tgatatcctg ttttgtatcc cgccttgcgc tgtcttcctt
     6601 tccacctcta cagggcggct cctgccagca gctctaaaat ataaactgcc gcaatggcgg
     6661 ctacggccac taccaccagg cttttcccct tatagcccag tacaatggcc accgctgttc
     6721 ctcctgccgc tgaaaacaga tgtcctgtgc tgaaaaagac gtccggaaac gtcagggctc
     6781 ccagaacggc ataaggcgta tagtccagaa aagagcggat aaaccgcgac cggatctgtt
     6841 ttctgaacac cgttacgggc agaaccctgg gaatataagt aaccagggcc atcagcgcca
     6901 cgcagattaa tactcgttta agctccattg ccgtctcctc ctgtctcctg tgctttctct
     6961 ctcatctttc catctgtctc ctttgctgtc tcttctgctg cctcgtccgc cgcatcctct
     7021 attttttcta ttttttctgt ctctccgctg tcatcggttc ccgggaacag ccatgcgccc
     7081 agacctgcgg cagccaccgt ggaaataatc acgcgaaagc cgtccgacag aaaagaaaac
     7141 acaggaatgt agttcagccc gcactgcacc gccaccgcta tgcagataat gcagagcaca
     7201 tgggcggagg ccttggccgc cggtataatc agtgcgataa acatcgcgta gagagcgata
     7261 cccatggcat tctgaagcgc ctggggaagc agggtggaaa tgcatcctcc catcagagtt
     7321 cccagattcc agcccgctac cggcatcaga atcagcccca gcataaacgg cgcggtcagc
     7381 gttcccggct ttaaagagcc caccacaaag gtttcgtctg taatgccgaa ggccagcgcc
     7441 agcctggcca gagttcccgt ttttctctcc agcttctggg acagagaaag ggacatcagc
     7501 atataccgta tattaatcac aaatgtagtc agcgccactt ccagataccc ggctccggca
     7561 aaaatcagat ttgtgccggc aaactggcct gcgctggtca ggttcgtcag ggaaatcacc
     7621 actgccaccc agatgggaag tcccccggaa acagccagaa atccgaaggt gaacgacact
     7681 ggaatgtagc cgatcccaat cggcagtccg ctttttatac cttttttaaa ttctcttctc
     7741 cagtccatct ctcatctaac catccttttc ctctccgaag cttccctccc cagagaaacg
     7801 ctcccgcttc atcttattca gccattccac tccctgttca attccttcct ccgaaaagtc
     7861 aaactgcttt ctcgtttttt tctcttctga agtagcgtcg tagccgtagg gctccggcca
     7921 tacagtcact gtaagaaccg ttttctcttc cccgtctgtt ttctccatcc tgtatctcat
     7981 gccccggtcg cttcccgtaa agttttcttt cttcagaaaa ttcaccggca ttacatcttt
     8041 tcgcataatc atgctattct cctcctgatc cccgccagaa cccgcagcct gactctgcct
     8101 gacattataa cacaaatact gctgtttgtg gatccagatt cctctctttt tcacctgtac
     8161 tccaaaaaat acttctgtat attattcatt ttgtttttta ttttattcaa atatagcttg
     8221 attttttctt gcatgtgttg tatatttata ttcatatttt tcataaatat acaaccatct
     8281 ggttctttct gcaaagcggc tttcttttct gccaaaaaaa agacgcctgt cagaaaacgt
     8341 ttatatggag gagaaaagca ttatgaaaga aaaagtgatt ttagcgtatt ccgggggcct
     8401 tgacaccact gccattattc cgtggctgaa agagcatttt gattacgagg tcatctgctg
     8461 ctgcatcgac tgcggtcagg gagaggagct ggacggtctg gaggagagag ccaagctctc
     8521 cggcgcgtca aagctttata ttgaagatat tgtagacgat ttctgcgatc actacattgt
     8581 tccctgcgtg caggcgggag ctgtctatga aaataaatat ctgcttggaa ctgccatggc
     8641 ccgccccggc attgccaaaa agctggtaga aattgcccgc aaggagggcg ccagcgcgat
     8701 ctgccacggc gctacaggaa aaggcaacga tcagatccgc tttgagcttg gaatcaaggc
     8761 tctggctcca gatctgaaaa tcatcgctcc ctggcgtatg accgacgttt ggaccatgca
     8821 gtcccgtcag gaggaaatcg actactgcaa agcccacggc atcgatcttc cgttttccgc
     8881 tgattccagc tacagccgcg acagaaatct gtggcatatc agccatgagg gcctggagct
     8941 tgaggatccg gcggctgagc cgaattacga tcacctgtta gtcctgggcg tcactcccca
     9001 gaaggcgcct gacgaagcgg aaaccgtcac tatgacgttt gaaaaaggcg ttccagcctc
     9061 tgtcaacgga actcccatga aagtgtccga catcatccgc acattaaacg aactgggcgg
     9121 aaagcatgga atcggaatcg ccgatatcgt cgaaaaccgg gtagtcggca tgaaatcccg
     9181 cggcgtttat gagaccccag gaggaaccat cctgatggaa gcccacgctc agttagaaga
     9241 gctggttctg gaccgtgcta ctatggaagt gaaaaaagag atgggtagca agctggccca
     9301 gattgtctat gaaggcaaat ggttcactcc tctccgcgaa gccgttcagg cgtttgttga
     9361 aaaaacacag gaatatgtaa caggagaagt ctccttcaag ctctacaagg gaaatatcat
     9421 taaagccggc acaacttccc cctactccct gtacagcgag tccttagcct cctttacgac
     9481 aggagaattg tacgatcatc acgacgccga cggtttcatc actctgtttg gacttccgtt
     9541 aaaagtacgg gccatgaaaa tggcagaggc agaaaaaaac aaataaacca ccgtttcata
     9601 gaaaaaggga aggctgcgga cggcctcccc tttctctttt ctgcgcttcc tgccaggcta
     9661 cgcaaaagga aatttataat ttctgattac aacctggaga tttctgtttc cattgtactc
     9721 attgatctcc ggataataaa taatatccat gacagttctg cctgcccgtt cttcctcaaa
     9781 agcgattccg tctgtaaaaa gaattccatc cataggcatt ccgcttcctc cctccagaac
     9841 aagctttacc acatttttat tctttccaat cacacggcag cttctgattc tcacctgctt
     9901 ctgcgcaaac agcggtttct catttccctg tccaaacggc tccagaatct tcagttcctc
     9961 caccagacgc tcgtttatgt aatcaatggg catcggcacg tcaatccaca gcttagcctt
    10021 aaagtcctcc tcagtcagcc ctgacctctc attcagctct ctcctgaact catcaatatt
    10081 ttcttccaga agagaaagcc ctgcggccat aggatgaccg ccaaatttca gcatcaggtc
    10141 ctttacctca gacagctttt ggaacatgtg ataggactcg atcgaacggc cggatccctt
    10201 caccgcctcc tcgctgcgcg tcagcacaat ggcaggcttc tggcagtatt ccctgagccg
    10261 tcctgcaata atgcccgcca gcgattcatg gcagtcagga aggaaaatga ccagcacctt
    10321 atcgttccga tactgagtgt cagccagtac cttcgcctct gccgtccaat gctccgtcat
    10381 atcctttctc atgtcgttga gatccttcag ctcctgcgcc agctcctctg ccgtctcctc
    10441 atcctttgcc agaagcatgg agagagccag ctttgccgtc tgaagccttc ccccggcatt
    10501 caggcaggga ccgataacaa atccaatgtg gtaggccgtt atgctgttta aatccaggtt
    10561 cgtcttttcc gccagcttct taagccccag atttttcgtg tgtcccagct ttttcagtcc
    10621 atattttaca atcatgcggt tctcatcctg gagcttcatc acgtctccca ctgtggcaat
    10681 agccgcaaac tccaaaagtt ccagccactc ctccctggag actccggatt cctcataaag
    10741 agcctgaacc agcttatatg ccaccacagc cccgcagatt tccggaaacg gatagctgca
    10801 gcttctctgc tttggatcaa tcaccgcatc tgccggcggc aggatttccc gttctccatc
    10861 tgcaggaacc tcgtgatgat ccgtcacaat cacagtcatc ccgaactctt tggccgtctg
    10921 aatctgggaa aatgcagaga tcccattgtc gcaggttaaa atcgtatcga ttccgtcttc
    10981 cgcagccgcc cggatcatcg attcattgat tccatagcca tccttaatcc ggtcaggaat
    11041 tgcatagtcc acatttcctc ccaggcgttt taaagcctgg taaagaatat aggtggagca
    11101 gactccgtca atatcgtagt ctcctacaat cctgattttc tgcccctcct tcagcttccg
    11161 ctttaaaata tccaccgctg gtctcatatc ctttaaaagc cagggggagt acagactgtc
    11221 caggtctccg taaagatacc tctcaatgtt ctccctgccc tcgattcctc tgtttcggat
    11281 tactctggct gtcaccggat caattccaaa ctgccttgca atcccatcaa aatctgctct
    11341 cttcgtctga agcatccaga tctgctctgc cattgtattt ctccttatct tcctagcaca
    11401 tagttgaatc ttgcctgttc cactgctttc ctatttccta gagccttcct ccattctcct
    11461 tcagccacat cctccgctct ctgtaatccg gcagaatttt ctccacctcc cgccagaaat
    11521 tggccgaatg attcatttcg attcggtgag ccagctcatg aaccaccaca tagtcgagaa
    11581 tctcatccgg aaccagagac agtttccagt taaagttcaa gtttcccttt ccgctgcagc
    11641 ttccccacct ggtcctctga tcccgaatcg aaactctccc ataggacacg cccatcacgg
    11701 aagcaaacaa gggcagcctc tcttccagct tcctgttcag cctttgcttt cccgtctgct
    11761 tctcagcctc tgtgtaagaa cgccgccaag aggcattctg aagcactttt tcccttgttt
    11821 ttaaaatcca ctccccatgc ctgcgggcga actcttccgc ctgcgcttct gtagctgttc
    11881 ttggaacgcg tactgtaacc tgtccgtctt cctcgatctg aagcgccatt gtctttctgg
    11941 acgttcttac gattctgcac ggaatctcta atatgtccgg ttccaggcta ccaggctgtc
    12001 ttctgaatgt attcgtaatc tgcaaatact gcatacattc tgtcctctct gaaatcaact
    12061 gtctgtgcgg cacgttccat cacactctcc atctcttttc caaagctctc cagcggagaa
    12121 cctgcctctg gctgaatcat ctccacacag gtattctcct ccatacccag cagctcggca
    12181 tacagctcat ccaagccccc ctcaaaatcg tccgggaaat ccagctctct tttcagaagc
    12241 tcgcagacct ccttctggct ctccatctgc ttcatatcaa tcgtcaccat tttcatgaaa
    12301 tattcctcct tctgcactgg cgctgtcaaa aacagccatt ttactgttct aaaaccttaa
    12361 aagctgtctg attcttatac gaattcctat gctgatttct atgctgattc ttacactgat
    12421 tcttatactt atactaattc ttatgctgat tcttataccg aatcatgcgc atcgcagaat
    12481 gtatcctctg atgcaaacat ttttttaaca gaaaaaagga cacctgcaat cagatgtcct
    12541 tcgctgtgtc ctgcccaagc aggaatctct accgtgcgtg agaagattcg aactcccgac
    12601 accttggtcc gtagccaagt gctctatcca gctgagctac acgcacattt gttagtgatt
    12661 tgtttcccta acaacgaatg ttattttaca cctattcgtt caaattgtca acaactattt
    12721 taaatttttt tgattttctt tttttaagtt ttttctcccg cttttccttc ttcaatctct
    12781 gtttttatct ctgttttttc atttcatcct ggttctgctt tcctttttta cctctgccgt
    12841 tcctctttcc atctattatc cgcatctttc tggtagctct gctgtattct gtatactgtg
    12901 tattccctat cctgttcata ccccaggctg caggcaagat gggcagaaat ctcattatct
    12961 gcatcccagc tgggatagcg tccctgttcc aggcagcgaa gtatcaatgc ggccccgcat
    13021 attttcccca gcccctgatt tctgaaatcc tctctggtat caatctgaat ttctattccc
    13081 ccagagtaaa cagcatagga agatgctcca gccaccagtt ctcccttata ttttaacact
    13141 gttcctatcc ctctttttct gtaatcctca tatccggaaa actgggaaat ccagtccccg
    13201 gcccaggaag tccgggacac ttcatcaaac agatcacggc attcttccat attcgtcaaa
    13261 gtgaaatctg cgtccaatcc atttacaatc ctaagcagtt ccttctgaga aaatccttcc
    13321 tctttccgct taaatgaata tctcttatag gatataacct tttctccata taccttttca
    13381 atcagcccct cccattccag agtctgcggc accaaaattt tcagctgatt ttcatactca
    13441 ctctttttgt gatacagtaa gttttcattt gctttgccgc caaaaaaaca gaagtctcca
    13501 atatccagtt ttgccgacat catctcttct gttgagtaaa cgtctcccat ctcgccttcc
    13561 agacacgata agaccatggt gttatgccat cctttaaata aagaggtaag acgcgaatat
    13621 tgttctctgc tgcatttttg aatcataatc ttttcccgcg cttttattta tgtgaaaaac
    13681 agaaataaca aaaagagcct tgatctctca agactcttcc tatgccgcag accggaatcg
    13741 aaccggtacg aagtttaacc ctcgcaggat tttaagtcct gtgcgtctgc cagttccgcc
    13801 actgcggctt ttgttatatc tgttttagac agataaatgg ggcctatagg gctcgaacct
    13861 atgaccctct gcttgtaagg cagatgctct cccagctgag ctaagacccc agataaatat
    13921 aaatggcttt cgccaaacga cccggatggg actcgaaccc acgacctccg ccgtgacagg
    13981 gcggcgctct aaccaactga gccaccgggc caaaattaaa acttaatttt gtatcaatta
    14041 ttttctttag tcagtgttag tggaccttcg gggactcgaa cccaggaccg accggttatg
    14101 agccggttgc tctaaccaac tgagctaaag gtccagataa ataagccgat gatcggactc
    14161 gaaccgataa cctgctgatt acaaatcagc tgctctgcca attgagccac atcggcatat
    14221 taaatgaccc caacgagatt cgaactcgtg ttaccgccgt gaaagggcga tgtcttaacc
    14281 gcttgaccat ggggccaaaa ctcaactcca cagtttccac tgtttcgctc ctatcatctc
    14341 gtaaatcagc tcgtgcaaaa tctacttcga atcatgtata ggtatcaaaa ctccccctgt
    14401 tggactcgaa ccaacgacac tgcggttaac agccgcatgc tctaccgact gagctaagga
    14461 ggattatctt cccccggatt cttactt
//
LOCUS       DBMDUW010000062        14102 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_2333_length_14102_cov_3.030355, whole genome shotgun sequence.
ACCESSION   DBMDUW010000062 DBMDUW010000000
VERSION     DBMDUW010000062.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 14102)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 14102)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14102
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2333_length_14102_cov_3.030355"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            421..1557
                     /locus_tag="ACZPCR_10295"
     CDS             421..1557
                     /locus_tag="ACZPCR_10295"
                     /inference="COORDINATES: protein motif:HMM:NF017760.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIR1231291.1"
                     /translation="MAYLTVLPLYILDRTQSLAFAGFFLMCTSLPAVLCSSFLGVLVD
                     RISRKKLIIFCDLCCAAIYAALLYFKEGQGNYIAWLMMASIMINILSNLFEISSKVLF
                     TELLEKAEIGRYNGLKSLTDNMASIAAPIAGTFLWGWLGFRCILALMGVLYLLSAVQE
                     SAIIYKVAFQKPERERGAGQAFLDGLRFISRDKNIRPLFLMVMLLNFFLGGMEEIMNP
                     GMVVQKYGINEALFGIAASVSIAGSICAGMLIFKSSQFSHKDRMTEFIVCNSAVMIGV
                     GGASIVLFPEKQLFFVVFLLCQFLIGLLTTCVNVPLSSKLQVSVPVEYQGRFFAVLAF
                     FSGLLVPAGSWYSGLLASYVGADWACMINNLFVIAVALAIRRRL"
     gene            1740..1865
                     /locus_tag="ACZPCR_10300"
                     /pseudo
     CDS             1740..1865
                     /locus_tag="ACZPCR_10300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007711935.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
     gene            1921..2082
                     /locus_tag="ACZPCR_10305"
     CDS             1921..2082
                     /locus_tag="ACZPCR_10305"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231292.1"
                     /translation="MNFIKGKAGLLLLLLSVMFILAVVWFCLFDMHIYAEPHGTFVEA
                     EESAGEMAA"
     gene            2082..2708
                     /locus_tag="ACZPCR_10310"
     CDS             2082..2708
                     /locus_tag="ACZPCR_10310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AA"
                     /protein_id="HIR1231293.1"
                     /translation="MGQTVFISLNQITQVHKKDVFLADIGEVYCSDPHVASRVKAVKA
                     ASIRENKEHNYIGNVMDIIEKIQQAAPGADVSNLGETDFIISYKPDKVPSMIWEWTKT
                     VFACLICFFGAMFAIMTFNNDANVKDVFREIYTLVMLREPDGVTVLELAYSVGLALGV
                     TVFFNHFSRAKLNLDPTPLEVEMRLYEDNVNKTLIQNSGRKESGNDVT"
     gene            2695..3150
                     /locus_tag="ACZPCR_10315"
     CDS             2695..3150
                     /locus_tag="ACZPCR_10315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AB"
                     /protein_id="HIR1231294.1"
                     /translation="MTLLKTWFLAFAGFTSGGVIAAGIFAFLAMIGVFPRVISRTKTR
                     RHIMLYETLLICGGAFGNALDLMEFPIPVGRIPLAGETAGQLLMTAAGLGSGVFVGCL
                     VMSLAETVKAVPVLNRRLHLSVGIQYMILAIALGKMAGALVQFCLFSQS"
     gene            3227..3679
                     /locus_tag="ACZPCR_10320"
     CDS             3227..3679
                     /locus_tag="ACZPCR_10320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015542242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoVA/SpoVAEb family sporulation membrane
                     protein"
                     /protein_id="HIR1231295.1"
                     /translation="MEVDKKAYGKYVDEITPKHNLPLNMARAFLTGGAVCTVGQLLIN
                     AFQAQGMEKEAAGIWTLLVLIGSSAFLTGLNLYQKLVKFGGAGALVPITGFANSVAAP
                     AIEYKAEGQVFGIGCKIFTIAGPVILYGLFSSWLLGVVCWLGKWMGIS"
     gene            4025..4723
                     /locus_tag="ACZPCR_10325"
     CDS             4025..4723
                     /locus_tag="ACZPCR_10325"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013053.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HIR1231296.1"
                     /translation="MKINQKYVSFYYQGMTEVPDMQLERSKTALLIIDMQKEFVNRDC
                     GDYLKAKEAGDEERWIPYHDRLDQVVIPNTKRLIQFFRENGMEVTYGRIACLKENGKD
                     RARVQSTYGWNNIHVPVGTREAEMVDELAPMPDDIVVNKTTDSVSLGTNYTQLLRNMG
                     IDTVVVTGIVTDQCVASSVRVLADQGFQIICVEDCCAAPDMELHDAELKIMNILYCNV
                     LSTDETIEVLKTAK"
     gene            4759..6117
                     /locus_tag="ACZPCR_10330"
     CDS             4759..6117
                     /locus_tag="ACZPCR_10330"
                     /inference="COORDINATES: protein motif:HMM:NF024910.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HIR1231297.1"
                     /translation="MKEKLKKELSLSQIIAMAAGGMIAAWMVEIKYWFEISGSGAVFS
                     LLTCCILVLPLCLIYSEMTSMLPYAGGENVWISNAFGWNVGWFSCWALVLLYIVAMPS
                     VAFGISSMLSYLFPVNFIQIKMIAGGIIIVWFLLTNLEIKFLAKIQNIMFWSTLAISI
                     CASCIFIFSDQWSFENLKPWFPTGFAGYSMGVGLLIMKFQGFDMIPQLVEESNIPKKK
                     LLIAFISSMFLTFLIYGLAIIAVGGIVSSEWMQQTDIVDPRVADMLGMHWLGLVIVVM
                     GIITCITTLSGFWLSASRTLYGGAKQGQFSKTFTAINRHGQPWKANLVIGILSLYFTV
                     FAPEKWINYIFTITGLSAGIIYFGVSVSFLKLRKTKPQWERPYKVKHGTLLGWLSIIF
                     TVWVIYTCAKSMDAGGWLAVGLYFALGIPFMAYAKHMQKKKPEEWKQIILSPDNMKEE
                     EE"
     gene            6228..7037
                     /locus_tag="ACZPCR_10335"
     CDS             6228..7037
                     /locus_tag="ACZPCR_10335"
                     /inference="COORDINATES: protein motif:HMM:NF012301.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1231298.1"
                     /translation="MYSVIVVDDDKETLELLGKEIDWQKLNCRLDGMAQTMEEGLFLV
                     EEKHPELIITDVHIERRREDLLQTLYEKNHSQKRPFVIIVSACRDFEEACRAIRYEAA
                     LYLTKPLRAEEIEDGICWVLERMRRRENGAADPDGEEEKDVSAGTLRELQRIRREMEQ
                     YSPFIQEAIRFIDSHLEQELSLTVICERLCLSHSYFSKKFKQETGRGYVSYVTMAKME
                     KARRMMEDPRNKANDVAKKLGYYDYSYFFQNFRRYFGCSPRQFKSHGKVSK"
     gene            7119..8159
                     /locus_tag="ACZPCR_10340"
     CDS             7119..8159
                     /locus_tag="ACZPCR_10340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006780000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HIR1231299.1"
                     /translation="MQKGKASIIFEEPPCIYSAAAIVGQKEGEGPLGACFDQVEADPM
                     FGQANWEAAESELQRRTALCNMEKSGISREKIRYLFGGDLLGQIVATSFGVSELEIPL
                     FGLYGACSTMGEALSLSAMTVGGGFADCVMAMASSHFASAERQFRFPLAYGNQRPFSS
                     TWTVTGCGSVLVGKRGLRDEKKSFRPMAQIAGITTGRIVDMEFRDSMNMGGAMAMAAV
                     DTILQNFRDLDVEPGWYDKIITGDLGSVGQKILFDFLEQAGFDVRGVHMDCGMTIFDS
                     ASQDTHSGGSGCGCSAVTFCSYILPKIQDGTWKRILFLPTGALLSQISFNEGQSVPGI
                     AHGVVIERAERR"
     gene            8161..8517
                     /locus_tag="ACZPCR_10345"
     CDS             8161..8517
                     /locus_tag="ACZPCR_10345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006780001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoVA/SpoVAEb family sporulation membrane
                     protein"
                     /protein_id="HIR1231300.1"
                     /translation="MDYLKAFLIGGLICAGVQVLMEKTKLLPGRIMVLLVMTGAVLGF
                     LGLYEPFAEWAGAGATVPLLGFGNTLWKGVKEGLETEGALGLFKGGLTASAAGISGAL
                     IFGYLGALLFKPKMKD"
     gene            complement(8668..11328)
                     /locus_tag="ACZPCR_10350"
     CDS             complement(8668..11328)
                     /locus_tag="ACZPCR_10350"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008955 - peptidoglycan
                     glycosyltransferase activity [Evidence IEA];
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HIR1231301.1"
                     /translation="MNYGRKETRRQIAAAGSRKKKYTNRLFLSFFKAALVLCLFVFVT
                     GFSAGIGMFKGIIDTAPDFNAESFAPSGYFSTIYDCEGNVTDTLVGTNANRIEASYEE
                     FPEDLINAFVAIEDSRFWQHSGIDLRSITRAAVGVLTNNYQGGASTLTQQLIKNTVFN
                     GGMETSSGARIERKIQEQYLALQLTKNVDRKIIITNYLNTINLGNNTLGVKAAALRYF
                     NKDVSELTLSECAVIAAITKNPSRLNPITGAKDNAERRATILQEMYNQDYITKEEQEE
                     ALADDVYSRIQNVDLANKENDTPYSYYTDELIEQVTEALKEELGYTDTQASNLLFSGG
                     LSIYTPQDPKMQAIVDEEISNPANYALAQYSIEYRLSVTHADGTTEHFSEGHVKNYFT
                     DTLGQTGYTGLFGSEEEARAAVEQYKSWLIKEGDSIIGESLSTTLQPQASFVLIEQST
                     GEVKAISGGRGEKKANRTLNRATNAKRQPGSAFKVITSFLPAVDTCGATLGSVYYDAP
                     YSIGDKSFRNWYANRGYMGYHNIREGIAYSMNIITLKCLVDTVTPQLGVEYAKKMGIT
                     TLVPEDVTPSLGLGGLTLGVTNLEMTDAFASIANGGEYREPVFFTKILDHNGKVLIEN
                     EPEPRRVMKGSTAFLITDAMADSVVSQSLYATPGSQPSTTSAAAAIPGMSTSGKSGTT
                     TSNNDLWFVGFTPYYTAGIWSGYDNNGSITGGTSYHKAIWRNIMTRIHEGLPDPGFVP
                     PDSVEKVEICRKSGKLPVPGVCSSDPRGDATYTEYFAKGTAPTETCDCHVRVSVCGVS
                     GGRPTAFCPENQLVSKTFMAVPDEGYTDDSKYAIPGTCSVHSGSSTIIVPNPGDGNDI
                     PFGPGYIPNSGGSSIEPGGNNIPIVPAAPD"
     gene            11523..12173
                     /locus_tag="ACZPCR_10355"
     CDS             11523..12173
                     /locus_tag="ACZPCR_10355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004608326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HIR1231302.1"
                     /translation="MKKSYKILYQAGEGEIVEKKSRFIATIRPVDSEEEALSFIAEMR
                     KKYWDATHNCTAFVIGENHEQMRCNDDGEPSQTAGRPMLDVLLGEDVHNCCAVVTRYF
                     GGTLLGTGGLVRAYSAAVKEGLRNCQILEKQLARKLTVETDYTGLGKIQYILGEEKIS
                     TLDSQYADKVSLTLLVPVDQLDPLMEKLTEGTNGRCVMEPGEQVWYGLQGKEIVFL"
     gene            12255..>14102
                     /gene="typA"
                     /locus_tag="ACZPCR_10360"
     CDS             12255..>14102
                     /gene="typA"
                     /locus_tag="ACZPCR_10360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HIR1231303.1"
                     /translation="MKTKREDVRNIAIIAHVDHGKTTLVDQLLRQSGVFRANQEVVDR
                     VMDSNDIERERGITILSKNTAVFYKGVKINIIDTPGHADFGGEVERVLKMVNGVILVV
                     DAYEGAMPQTKFVLRKALELNLPVIVCLNKIDRPEARPDDVIDEILELFMDLDASDEQ
                     LDCPFLFASARSGFAKKNLEDPDVDMSPLFETILEYIPAPEGDPETETQVLISTIDYN
                     EYVGRIGVGKIDNGSLKVNQDCVIVNHHEPDKFRKVKIGKLYEFEGLNKVEVSEAGIG
                     AIVAISGISDIHIGDTICSPEKPEAIPFQKISEPTISMDFMVNDSPLAGLEGKYITSR
                     HIRERLFRELNTDVSLRVEETDSPDCFKVSGRGELHLSVLIENMRREGFEFAVSKAEV
                     LYHYDERNTKLEPMEIAYVDVPEEFTGAVIQKLTSRKGELQGMSPIGGGYTRLEFSIP
                     SRGLIGYRGEFLTDTKGNGILNTSFDGYGPFKGELSYRKQGSLIAFEAGESITYGLFN
                     AQERGTLFIGPGVKVYSGMIVGQSAKPEDIELNVCKTKKLTNTRSSSSDEALRLTPPR
                     EMSLEQCLDFIDTDELLEVTPTSLRIRKKILDPTLRKRAMISRKEAEKNR"
BASE COUNT         3653 a         3011 c         3965 g         3473 t
ORIGIN      
        1 aaagaacttg aagcacaaga catatttgct gaaaatctgg aaaatgaaga ctatgtagta
       61 aaatactcaa catgatctaa ttgtattaat aattagacag agggggaggt tttatttaaa
      121 gtataaagcc tcctcttttg tttggttaaa aaatattttg ctactattat aagagaaatt
      181 aagatagaaa ctcttgagga taatgttaaa atttgggaaa aataaaaatt tgctatttgg
      241 taactgacag ccaattagtt atgatattag aatagtagtt cttatctatt cctgtaaaat
      301 ttgtgtgatt acctctcgtc tgtgtaaaat ggctgattat tttttgggga aagagtgact
      361 ggttcgatga aaaatattat ttttttaata cttggaagag caacctctaa atttggaagt
      421 atggcgtatt taacagtctt gccgctgtat atcctggaca ggacgcagag cttggcgttt
      481 gcgggatttt ttttgatgtg tacctcgctg ccggcggtac tgtgcagttc atttttaggg
      541 gttttagttg acaggataag ccggaagaag ctgattatat tctgcgattt atgctgtgct
      601 gccatttatg ccgcgctgct gtattttaag gaagggcagg gcaattatat tgcatggctc
      661 atgatggcaa gcattatgat caatatctta agcaatctgt ttgaaatttc gtccaaggtg
      721 ttatttacag aattattaga gaaggcggag ataggacgat ataatgggct gaaaagctta
      781 actgacaaca tggcgtccat cgctgccccc atagcgggca cctttttatg gggatggctg
      841 ggctttcggt gcattttggc tttgatggga gttctttacc tgttatcggc agttcaggaa
      901 tccgcaatta tttataaagt cgcgtttcag aagccagagc gtgagagagg ggccggccag
      961 gcatttcttg acgggcttcg atttatcagc cgtgataaaa atatcaggcc gcttttttta
     1021 atggtgatgc ttcttaactt ttttctcgga ggtatggagg aaattatgaa tcctggaatg
     1081 gtggtgcaga agtatgggat caatgaggcc ttatttggta ttgccgcctc tgtttccata
     1141 gcaggcagca tatgtgcggg gatgttaatt tttaaaagct cccaattcag ccataaggat
     1201 agaatgacag aatttattgt ctgcaacagc gcagtgatga ttggggtggg aggggcgtct
     1261 attgtcctgt tccctgaaaa gcagctattt tttgtcgtat ttttgctgtg tcagttcctg
     1321 atcggcctgc tgactacgtg tgtgaacgtc ccgctaagct caaaactgca agtttccgtc
     1381 ccagtggaat atcaggggag gtttttcgcg gtattggcat ttttttcagg gctgctggtt
     1441 ccggcgggca gctggtactc ggggcttctg gcctcttatg tgggagcaga ctgggcgtgt
     1501 atgataaaca atctttttgt tattgcagtc gccctggcca taaggagaag gctgtagaaa
     1561 agcaggttga atatatagat aatatcttgc aattcattac atttttctaa aattaattca
     1621 tatatccggg aaagtattct atactcagct taacagacat agagaaggca tccagcgttc
     1681 aggaacaggc agcagccttg actgaaatca cacagcaggt agacgaaaat acccagctga
     1741 ttgtgagacg ctatttctat gaccagacac agacaaaaat tgcagaagcc atggggattt
     1801 cacaggttca ggtttccagg atggagaagc ggattttaaa gaaaatgcgg gaaggctttg
     1861 aataaaaaca gaaattttct ccatactaat ctgcaaacga atagaaaagg atgtgagaaa
     1921 atgaatttta taaaaggaaa ggcaggtctg cttctgctcc ttttgagcgt catgtttatt
     1981 ttagccgtcg tatggttctg cctgtttgac atgcacattt atgcggaacc ccacggaacc
     2041 tttgtggagg cagaagaaag cgccggggag atggcagcct gatgggacag accgtattta
     2101 taagcctgaa tcagattacg caggtacaca aaaaagacgt atttttagct gatattgggg
     2161 aggtttactg cagcgatccc catgtggcga gccgtgtgaa ggcggtgaag gcagcgtcga
     2221 tccgggaaaa taaggaacac aattacattg gaaatgtgat ggatatcatc gaaaagatcc
     2281 agcaggcggc tccgggtgca gacgtgtcaa atctgggaga gacagatttc attatctcct
     2341 acaagccgga caaagttcct tccatgatct gggaatggac aaagacggtg tttgcctgtc
     2401 tgatttgctt ttttggagcc atgttcgcca tcatgacctt taacaatgac gccaatgtga
     2461 aagatgtgtt ccgggaaatt tacacgctgg taatgcttcg ggaaccggac ggggtaacgg
     2521 tgctggagct ggcctactcg gtagggctgg ctctgggagt caccgtcttt ttcaatcatt
     2581 tttccagagc gaagctgaac ctggatccga cgcctctgga ggtggaaatg cgcctgtacg
     2641 aggacaatgt caacaaaacc ttaatacaga acagcggcag aaaggagtcg ggcaatgacg
     2701 ttacttaaga cgtggtttct ggccttcgcc ggatttacgt caggaggcgt gattgcggct
     2761 ggaatctttg cgtttctggc catgatcggc gtatttccca gggtgatttc caggacaaag
     2821 accagaaggc atatcatgct gtacgagacg cttctgatct gcggcggcgc ttttgggaat
     2881 gcgctggatc tcatggaatt tcccattcct gtggggcgga ttcctctggc cggggagacg
     2941 gcaggacagc ttttaatgac agcggcaggg cttggatccg gcgtgtttgt agggtgcctc
     3001 gtcatgtccc tggcggaaac ggtaaaagcg gttcctgtcc tgaacaggcg ccttcacctg
     3061 tcagtgggca ttcagtatat gattctggcc attgccctgg ggaaaatggc tggggccctt
     3121 gttcagttct gcctgttctc tcagagctga gattcggaca gaggcgaagc ggagcaggaa
     3181 agatgccagc cgggattccg ggacagagta aaaggagaaa aaaagcatgg aagtagataa
     3241 aaaagcatat ggaaaatacg tggatgaaat tacgccgaag cacaatcttc ctctgaacat
     3301 ggccagggcc tttttgacgg gaggcgcagt ctgcacagtg ggacagcttc tcatcaacgc
     3361 ctttcaggct cagggaatgg aaaaggaggc cgctggaatc tggacgcttc tggttctgat
     3421 tggatccagc gcgtttctga caggactgaa tttgtatcag aagcttgtaa aattcggagg
     3481 agccggagcg ctggttccca taacgggatt tgctaattcc gtggccgccc cggctatcga
     3541 gtacaaggcg gagggacagg tattcggaat cggatgcaag atttttacca tcgccggtcc
     3601 ggtgatttta tacgggcttt tcagcagctg gcttttggga gttgtctgct ggctggggaa
     3661 atggatgggg atatcataga aaaagaaaaa caaacaatga tagaaaaatt caaataaagg
     3721 aatgttttca atgatttcgc aagaatgaga aaatattcct tttttgatgc taggaatcgg
     3781 ataaaaagat gagaaaatga aaaagtataa aaaattgaca tcattgaccc gcattgattg
     3841 tccaaaattg gcaaatatag tcaacaaaat gataatatct gaaagagtaa aaaaatggtt
     3901 ctgggaaaaa catgtaatat tttattcttt attggtttaa attttacatt tatagaaaaa
     3961 agagaaaaaa taccatataa tatgctttaa ttaaaagaaa agtgaattat aaggaggtaa
     4021 atgtatgaaa attaaccaga agtatgtgtc cttttactat cagggaatga cggaagttcc
     4081 tgatatgcag ctggaacgca gcaagacggc gctcctgatt attgacatgc agaaagaatt
     4141 cgtaaacagg gactgcggag actacttaaa ggcaaaggaa gcgggagacg aggagaggtg
     4201 gattccttac catgaccgtc tggatcaggt ggtgattccc aatacaaagc gtctgataca
     4261 gtttttccgg gaaaacggca tggaggttac atacgggcgg attgcctgcc tgaaggagaa
     4321 cggaaaggac agagccagag tgcagagcac ctatggctgg aataatatcc atgtgccggt
     4381 gggaacgaga gaggcggaga tggtggatga actggctccc atgcccgacg atatcgtggt
     4441 aaacaagacg acggacagcg tttccctggg aacgaactac acgcagctgc tgagaaatat
     4501 ggggattgac acagtggttg taacaggaat cgtgacggat cagtgcgtgg cctccagcgt
     4561 ccgggtgctg gcggatcagg gctttcagat tatatgtgtc gaggactgct gcgctgcccc
     4621 tgatatggag ctgcacgacg cggaattaaa gattatgaac attctgtact gcaatgttct
     4681 cagtacagac gagacgatag aggtgttaaa gacagcaaaa taggaatcaa ttaagaaggc
     4741 tttcgggggg agatgcctat gaaggaaaaa ctgaaaaaag aattgagctt atcgcagatt
     4801 atcgccatgg cggccggggg gatgatcgcc gcctggatgg tagaaattaa gtactggttt
     4861 gagatatctg gttcaggagc cgtcttttcc cttctcacct gctgcattct ggtgcttccg
     4921 ctgtgtctga tttattctga gatgaccagt atgctgccct atgcaggagg agaaaacgtg
     4981 tggatttcca atgccttcgg ctggaatgta ggctggtttt cctgctgggc tctggtactt
     5041 ttgtacattg tagccatgcc gtcagtggcg tttggaatct ccagtatgct gtcctatctg
     5101 tttcctgtca actttattca gatcaagatg atagcaggcg ggattattat tgtctggttt
     5161 cttctgacaa acctggaaat taagttttta gccaaaattc aaaatattat gttctggagc
     5221 accctggcca tctccatctg cgcgtcctgc atcttcattt tcagcgacca gtggagcttt
     5281 gaaaacttaa agccctggtt tcccaccggc tttgccggat acagcatggg tgtgggactt
     5341 ttaattatga agtttcaggg ctttgacatg attccccagc tggtagagga atccaacata
     5401 ccgaagaaga agctgttaat tgcttttatt tccagtatgt ttctgacctt tttaatttac
     5461 gggctggcta tcatagcggt aggcggaatt gtgtcaagcg aatggatgca gcagacggac
     5521 attgtggatc ccagagtggc ggacatgctg gggatgcact ggctggggct ggtgatcgtg
     5581 gtaatgggaa ttatcacctg tattaccacg ctgtcaggct tctggctcag cgcctccaga
     5641 accctttacg gaggagccaa gcagggacag ttttccaaga ccttcacagc gattaaccgc
     5701 cacggacagc cgtggaaggc gaacctggtc attggaatcc tttctctcta ttttaccgtg
     5761 tttgcgcctg agaaatggat caattacatc tttactatca caggcctgtc ggcaggaatt
     5821 atttactttg gagtttccgt ctctttctta aagctgagaa aaacgaagcc tcagtgggag
     5881 cggccttaca aagtaaagca tggaacgctg cttggatggc tttccattat ctttactgtc
     5941 tgggtgatct atacctgcgc caagagcatg gacgcaggcg gatggctggc ggtaggcctt
     6001 tattttgctc ttggaattcc gtttatggcc tacgcaaagc atatgcagaa gaaaaagccg
     6061 gaggagtgga agcagatcat tctgtctccg gacaacatga aggaggaaga ggaataaaaa
     6121 ggttccttct ggaaatcctg aaatcatagt acctgaggtc tgccgggcag aagcgctttc
     6181 tggccggcag acagactgac agaatttaga ataaaggaca ggatgatatg tactcggtga
     6241 tagtggtaga tgatgataag gagaccttgg agctgcttgg aaaggagata gactggcaga
     6301 aattaaactg cagactggac ggaatggccc aaaccatgga ggagggcctt tttctggtgg
     6361 aggaaaagca tccggagctg attattacag acgttcacat cgagcggcgc agagaagatc
     6421 tgctccagac tctctatgag aaaaatcaca gccagaagag gccgtttgtg attattgtga
     6481 gcgcctgcag agattttgag gaggcctgca gggcaatcag atacgaagcg gctctgtatc
     6541 tgacaaaacc cctccgggcg gaggagatag aggatggaat ctgctgggtg ctagaacgga
     6601 tgcggcgaag ggaaaacggc gccgcagatc cggacggaga ggaggaaaag gacgtttcag
     6661 caggcacatt aagggagctt cagagaatcc gcagggaaat ggaacagtat tctccgttta
     6721 ttcaggaggc aatccgcttt attgacagtc atctggagca ggagctgtcc ctcactgtga
     6781 tctgtgaaag actgtgtctg tcccactcct atttcagcaa aaaattcaaa caggagacag
     6841 gaagaggata cgtatcctat gtaaccatgg ccaagatgga gaaggccagg agaatgatgg
     6901 aggatcccag aaataaagcc aacgatgtgg ccaaaaagct gggctactat gattactctt
     6961 acttttttca aaacttcagg cggtacttcg gctgttctcc cagacagttt aaaagtcatg
     7021 gaaaagtttc caaataaggg gggaacagaa taaaaatctc ttttgcgggc agtctaaaaa
     7081 gagcgggcag cgtcgtctgc cgctcaggag gaagatttat gcaaaaggga aaagccagta
     7141 ttatatttga ggaacctccc tgcatctatt ctgccgcagc cattgtgggg cagaaggagg
     7201 gagaagggcc gctgggagcc tgctttgatc aggtggaggc ggaccccatg tttggacagg
     7261 caaactggga ggcggcggag agcgagcttc agagaaggac tgccctctgc aatatggaaa
     7321 agagtggtat ttccagggaa aagatacgtt acctgtttgg aggcgatctg ctggggcaga
     7381 ttgtggctac ctcttttggc gtatcagagc tggaaattcc tctgtttggc ctttatgggg
     7441 cctgctctac catgggagag gctttaagcc tttcagctat gacggtggga ggaggctttg
     7501 ccgactgcgt catggctatg gcgtccagcc attttgccag cgcggagagg cagtttcggt
     7561 ttccgctggc ctatggaaat cagaggccgt tttcttctac ctggacagtg acgggatgcg
     7621 gttctgtgct ggtggggaaa agggggctca gagatgagaa aaagagcttc cggcctatgg
     7681 cgcagattgc agggatcacc accggcagga tcgtggatat ggagtttcgc gattccatga
     7741 acatgggagg cgctatggcc atggcggcgg tggatacgat tctccagaac ttcagggatc
     7801 tggatgtgga acctggctgg tacgacaaga ttattacagg agatttggga tccgtaggac
     7861 agaaaatcct gtttgacttt ctggaacagg cgggattcga cgtgagaggc gttcatatgg
     7921 actgcggaat gacgatcttt gacagcgcct cccaggatac ccacagcggc ggaagcggct
     7981 gcggctgctc ggctgtgaca ttctgctcct atatccttcc taaaattcag gatggcacat
     8041 ggaagaggat tctgtttctg cccacagggg cgcttttgtc gcagatcagc tttaatgagg
     8101 gacagagcgt ccctggaatt gcccacggcg tagtgattga gcgggcggaa aggagatagg
     8161 gtggattatc tgaaagcatt tttgattggc ggtctgatct gcgccggagt gcaggtactc
     8221 atggaaaaga caaagcttct tccaggaaga attatggtgc tcctcgtgat gacaggagct
     8281 gttctgggtt ttctggggct ttacgagccg tttgcagagt gggccggagc cggggccacg
     8341 gttcctctgc tgggctttgg caacactctg tggaagggag tgaaggaagg cctggagaca
     8401 gaaggcgccc tggggctttt taagggaggg ctcaccgcgt ctgccgccgg aatttcagga
     8461 gccctgattt tcggatatct gggagccttg ctgtttaagc ccaagatgaa ggactgagaa
     8521 tcagacagag cgaaataagg caataacagg aaataaaaaa acagaagaaa atggaaggcg
     8581 cacaaaagaa agcaggtaaa aagacctgag acaggataag gaaaacgtcc tgtttcaggt
     8641 cttttttcgc agtgcgcagg aaacggttta atccggcgca gccggcacga tggggatatt
     8701 gtttcctccc ggctctatgg aagaaccgcc ggaattcgga atatatccgg ggccgaaggg
     8761 aatatcgttt ccatcgcctg gattgggaac gataatggtg gaggaaccag agtgtacgct
     8821 gcaggttcca ggaatcgcat attttgaatc atctgtatag ccctcgtcgg gaactgccat
     8881 aaaggttttg gatacaagct ggttttccgg acagaaggca gtgggccggc cgccggacac
     8941 gccgcagaca gagacgcgga catggcagtc gcaggtctcg gtaggagcgg ttcccttggc
     9001 aaagtattcg gtgtaggtgg cgtcgcctct cggatcggag ctgcacacgc ctggaaccgg
     9061 aagcttgcct gattttcggc agatttccac cttttccacg ctgtcaggcg gtacaaagcc
     9121 aggatccgga aggccttcgt ggattctcgt catgatattt ctccagatgg ccttgtggta
     9181 ggaggttcct cctgtaatgc ttccgttgtt gtcgtagccg gaccagatgc ccgccgtata
     9241 gtagggcgta aagcctacga accacaggtc gttgttgctg gtggtcgtac cgctttttcc
     9301 ggaggtggac attccgggaa tggcagcagc cgcgctggtg gtgctgggct gggaaccggg
     9361 cgtggcgtag aggctctggc ttaccacaga atctgccatg gcgtctgtga tcaggaaagc
     9421 ggtagaaccc ttcatgacac gtctgggttc cggttcgttt tcaatcagga ccttgccgtt
     9481 gtgatccaga atctttgtga agaacacagg ctctctgtac tcgccgccgt tggcaatgga
     9541 ggcgaaagcg tctgtcatct ccagattggt gacgcctaat gtcagtccgc ccaggcccag
     9601 agacggggta acgtcctccg gcaccagagt ggtgattccc atttttttgg catattccac
     9661 acccagctgg ggagttaccg tatctaccag acatttcagg gtaatgatgt tcatggagta
     9721 agcgattccc tcccggatgt tgtggtagcc catgtagccg cggttagcgt accagtttcg
     9781 gaagctttta tctccaatgg agtaaggagc gtcatagtaa acgcttccca gagttgcccc
     9841 gcaggtatcc acagcgggca ggaaggaggt aatgacctta aaagctgaac ccggctgacg
     9901 cttggcgttc gtagcgcggt ttaaggtacg gttggctttc ttctcgcccc ggccgccgct
     9961 gatagccttg acctcgccgg tagactgctc gatcagaacg aaggacgcct gaggctgcag
    10021 cgtggtggaa agagattctc ctataataga gtctccctcc ttgatcagcc aggatttata
    10081 ctgttccaca gccgccctgg cttcctcctc gctgccaaat agtccggtgt atccggtctg
    10141 tcccagcgta tcggtaaaat aatttttaac atgtccctcg gaaaaatgct cggtggttcc
    10201 gtcggcatgg gtgacagaca gacggtattc aatggaatac tgagccagcg cgtagttggc
    10261 gggattgctg atctcctcgt ccacaatggc ctgcatcttc ggatcctggg gcgtgtaaat
    10321 gctcaggccg ccgctgaaca gcaggttgct ggcctgggta tccgtatatc ccagctcctc
    10381 cttcagggcc tctgtgacct gctcaatgag ctcgtccgta tagtaggaat agggagtgtc
    10441 gttctccttg ttcgccagat ccacgttctg gattctggaa tacacgtcgt cggccagggc
    10501 ctcctcctgc tcctccttgg tgatgtaatc ctgattgtac atctcctgga gaatggtggc
    10561 ccgccgttcg gcgttgtcct tggctcctgt aatgggattc aggcgggaag ggtttttcgt
    10621 gatggcagcg atgaccgcgc attccgacag agtcagctcc gacacatcct tattgaaata
    10681 gcgcagagcc gccgccttga cgcccagagt gttgtttcca aggttaatcg tattcaggta
    10741 attcgtaata ataattttcc gatccacgtt tttggtgagc tggagcgcca gatactgttc
    10801 ctggatttta cgctcaattc tggcgccgga gcttgtctcc ataccgccgt tgaaaaccgt
    10861 gtttttaatg agctgctgag tcagggtgct ggcgccgccc tgataattat tggtcagtac
    10921 gcccaccgcc gctctggtaa tggaacgcag gtcaatgccg ctgtgctgcc agaagcggga
    10981 atcctcaata gccacaaagg cgttgatcag atcctccgga aattcttcgt aggaagcctc
    11041 gatgcggttg gcgttcgtgc ccaccagagt gtccgttaca ttgccctcac agtcgtaaat
    11101 cgtggaaaaa taaccgctgg gagcaaagct ctcggcatta aaatcagggg ctgtgtcaat
    11161 gatgccctta aacattccga ttccggcgct gaagccagtc acaaagacaa acaggcacag
    11221 cacaagagcc gccttaaaaa aagaaagaaa gagccgattc gtatatttct ttttgcggga
    11281 accagcggcc gcaatctgcc gtctggtttc ttttctgcca taattcatac caggcctcct
    11341 ttagcttacc attatagcaa aagttttcag ataattcaag actcgcagtt cccgcccaga
    11401 ctgcagtttt tgtccgggca gcttccctgt taataaacag gagagatctt tctggttgca
    11461 atctgttcaa attaataata tactcaaaaa aacagaaaga aattacgaca gggagagatt
    11521 ccatgaaaaa aagctataaa atcctctacc aggccgggga gggagagatt gtagaaaaaa
    11581 aatcccgatt tatcgccacg atccggccgg tggactcaga ggaggaggcg ctgtccttta
    11641 tcgctgagat gagaaaaaaa tactgggacg ccacccacaa ctgcacggcc tttgtcattg
    11701 gggaaaacca tgagcagatg cggtgcaatg acgacggcga gccatcccag acggctgggc
    11761 gtcccatgct ggacgtgctt ttgggggagg acgtgcacaa ctgctgcgcg gtagtgaccc
    11821 ggtatttcgg aggcacgctt ctgggaacgg gaggcctggt gagagcctat tcggcggcag
    11881 tgaaggaggg ccttagaaac tgccagatcc tggagaagca gctggccagg aagctgacgg
    11941 tggaaaccga ctacacaggt cttggaaaaa ttcagtacat tctgggagaa gagaagattt
    12001 caactctgga cagccaatat gcagataagg tatctctgac gctgctggtt cctgttgatc
    12061 agctggatcc tttgatggag aagctgacgg aaggcaccaa cggccgctgc gtcatggagc
    12121 cgggagagca ggtctggtac gggcttcagg gaaaggagat tgttttcctg taaaataacc
    12181 ttgaacttag gcacggttaa tgataaaata tcaagttgtg taaaaataag aagaaaagag
    12241 agagatagat tattatgaag acaaagcgtg aagatgtcag aaatattgcg attattgccc
    12301 atgtagacca tggcaagacg acgctggtag atcagctgct gcgccagagc ggcgtgttca
    12361 gagccaacca ggaggtggta gaccgcgtca tggactccaa tgatattgag agagagcgcg
    12421 gaattacaat tctttccaag aacacagccg tattctacaa gggagtaaag atcaacatta
    12481 tcgacactcc aggccacgct gatttcggcg gcgaggtaga gcgggtactt aagatggtaa
    12541 acggcgtaat cctggtggtg gacgcttacg agggagccat gcctcagacc aagtttgttc
    12601 tgagaaaggc gctggagtta aatcttcctg ttattgtgtg cctgaacaag atcgaccgtc
    12661 cagaggccag accggacgac gtcatcgacg agattctgga gctgtttatg gatctggacg
    12721 cttccgacga gcagttagac tgtccgttcc tgttcgcttc cgcccgttcc ggcttcgcga
    12781 agaagaatct ggaggatccg gacgtagata tgtctccgct gtttgagact attttagagt
    12841 acattccggc tccggaggga gatccagaga cagagacgca ggtgctcatc agcaccattg
    12901 actacaatga gtacgtaggc cgcatcggag tgggaaaaat tgacaacgga tccctgaagg
    12961 tgaatcagga ctgcgtcatt gtaaaccacc atgagccgga caagttccgt aaggttaaga
    13021 ttggaaagct ctatgagttc gagggactga acaaggtgga ggtatcagag gccggaatcg
    13081 gcgcgattgt agctatttcc ggaatttccg acatccacat cggagatacc atctgttctc
    13141 cggaaaagcc ggaggccatt ccgttccaga agatttccga gccgaccatt tccatggact
    13201 tcatggtaaa cgacagcccg ctggccggac tggagggcaa gtacattact tcccgccaca
    13261 tccgtgagag gctgttcaga gagctgaaca cagacgtgag cctgagagtg gaggagacag
    13321 attccccgga ctgctttaag gtgtccggcc gcggcgagct tcacctgtct gttctgattg
    13381 agaacatgag aagagagggc tttgagtttg ctgtgagcaa ggcagaggtg ctctatcact
    13441 acgatgagag aaataccaag ctggagccga tggagattgc ctacgtggac gtaccggagg
    13501 agtttacagg cgcggtaatt cagaagctta ccagccgcaa gggagagctg cagggcatga
    13561 gccctatcgg cggcggctac accagactgg aattttctat cccgtccaga ggcttaatcg
    13621 gctacagagg agaattcctg acagacacca agggaaatgg tatcttaaat accagctttg
    13681 acggatacgg cccgttcaag ggagagctgt cctacagaaa gcagggctct ctgattgcct
    13741 tcgaggccgg agaatccatt acctacggcc tgttcaacgc ccaggagaga ggaactctct
    13801 ttatcgggcc tggcgtgaag gtatactctg gcatgatcgt gggacagagc gcaaagccgg
    13861 aggatattga gctgaatgtc tgcaagacaa agaagctgac caacacccgt tcctccagct
    13921 ccgacgaggc gctgagactg actccgccga gagagatgag cttagagcag tgtctggact
    13981 tcattgacac agacgagctt ctggaggtga ctcccacaag cctcagaatc cgcaagaaga
    14041 ttctggatcc gactctgaga aagagagcca tgatcagccg gaaagaggca gaaaagaata
    14101 ga
//
LOCUS       DBMDUW010000063        13975 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_2358_length_13975_cov_2.342439, whole genome shotgun sequence.
ACCESSION   DBMDUW010000063 DBMDUW010000000
VERSION     DBMDUW010000063.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 13975)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 13975)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13975
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2358_length_13975_cov_2.342439"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            205..1812
                     /locus_tag="ACZPCR_10365"
     CDS             205..1812
                     /locus_tag="ACZPCR_10365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HIR1231304.1"
                     /translation="MFSKIVSCGIRGVEGYQVAIETDISSGGLPSLTMVGYLSEEVRE
                     AQERVRTALRNSGFLLPPRRITINLSPAGLRKDGTAFDLAIAVSILCCLEDELSKTAS
                     QAVFLGELGLNGEIKPVNGMISRVYCARQAGFSRCFVPRENVKEGTVVEGVEIVGVSN
                     LLEQVELLRHPDRIKGRWFDGKSFEKSLKQRTEAAVSSQTGAEEAEAAALDYADICGQ
                     TTVKRAMETAAAGRHSCLLIGPAGTGKTMAARRLPSILPPITLEESIEVSKVYSICGL
                     LPKDLPLITERPFRAPHHSITAQSLAGGGRNPRPGEISLASGGVLFLDELTEFPGRIL
                     DLLRQPLEEKRITVTRLSGILEFPADCMLICAMNPCLCGKFPSEKCTCSESQIRRYLG
                     KVSGPFLDRIDIGVEVPPVPCGELRGTARAGEKRSEESSAAMRKRVEKARNMQEKRFA
                     GLSIRCNSEMGPAEIREFCSLLPEDEAFLMAVYRQYGFSARGFDKILKVARTVADLDG
                     ADQIGRIHLCEAVSYRSFEKKYWGAKK"
     gene            1809..2906
                     /gene="dprA"
                     /locus_tag="ACZPCR_10370"
     CDS             1809..2906
                     /gene="dprA"
                     /locus_tag="ACZPCR_10370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007718022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HIR1231305.1"
                     /translation="MITEKEYLHWLCHVPGLKADKMRRLMEQAGSFKDIYYMKEQELK
                     SCLFLTARERNAILELKKQLDLTREEYHRLKERRIEFTTVFDSGYPERLRKLPGMPLG
                     LFVKGRMPDDSRPSAAVIGARGCSYYGKEEARYIARELARSGVQIVSGLAMGIDGAGH
                     AGALEAGQETYGVLGCGIDICYPKENFRLFERMERQGGIITEFLPGTPPYSGNFPMRN
                     RIISGLSDLVIVVEARKRSGSLITVGFALEQGKEVLAVPGRVTDPLSAGCNELIQTGA
                     GVLLTPDDALDLLGMKSEKNGNIVKKHENGLVKNEKMVYSCLDLQPKHLEQIVTESGL
                     PAGECMAVLLKLELERFAVQTSNQYYVRKFK"
     gene            2916..5015
                     /gene="topA"
                     /locus_tag="ACZPCR_10375"
     CDS             2916..5015
                     /gene="topA"
                     /locus_tag="ACZPCR_10375"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HIR1231306.1"
                     /translation="MAKNLVIVESPAKVKTIKKFLGANYEVDASNGHVRDMPKSQLGI
                     DIEHDYEPKYITIRGKGDILAKLRKEVKKADKIYLATDPDREGEAISWHLSKALKLED
                     CKDKKVYRITFNEITKNAVKAALKSPRAIDMNLVDAQQARRVLDRMIGYRISPLLWAK
                     VKRGLSAGRVQSVALRMICDREEEISSFIPEEYWNLEADLRAKGSRKKLAAKFYGTRE
                     GKLPLRTKEEVDQVIENLEGAQYVVDEVKTGERVKKAPIPFTTSTLQQEASKTLNFST
                     QKTMRLAQQLYEGVDIQGRGTIGLITYLRTDSTRIAEEADKVARAFIRETYGDSYVAT
                     EETAKKSSAKIQDAHEAIRPTDISLTPVLVKESLARDQFRLYQLIWKRFAASRMQAAV
                     YETTSVRVAAGEEQGGYLFTLSASKLKFDGFMSVYVQEEEKEENTVLSEKLEKGAVLS
                     CEQLGSSQHFTQPPSHYTEASLVKALEEQGIGRPSTYAPTITTILARRYVVKENKNLY
                     VTELGEVVNGMMKKAFPSIVDTAFTANMEYLLDRIGDGTVPWKTVIENFYPDLEEAVT
                     EAEKKLEAVKIADEVSDVPCDLCGRMMVIKYGPHGKFLACPGFPECRNTKPYLEKIGV
                     ACPKCGKELVIRKTKKGRKYYGCENNPECDFMSWQKPSPEACPECGGLMVEKGSKLLC
                     INEECGYVKINKKQSQE"
     gene            5228..6007
                     /gene="codY"
                     /locus_tag="ACZPCR_10380"
     CDS             5228..6007
                     /gene="codY"
                     /locus_tag="ACZPCR_10380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007858080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HIR1231307.1"
                     /translation="MSVQLLDKTRKINKLLHNNHSHKVVFNDICEVLSEILQSNILVI
                     SKKGKVLGVAICPGIDEIEELIEDQVGGFVDHMLNERLLNVLSTKENVNLATLGFAEE
                     NVKKYQAIITPIDMSGERLGTLFIYKSDEQYDIDDIILSEYGTTVVGLEMMRSVNEEN
                     AEETRKIQIVKSAISTLSFSELEAITHIFDELEGSEGILVASKIADRVGITRSVIVNA
                     LRKFESAGVIESRSSGMKGTYIKVLNDVVFDELKALKAENK"
     gene            complement(6114..7952)
                     /gene="glmS"
                     /locus_tag="ACZPCR_10385"
     CDS             complement(6114..7952)
                     /gene="glmS"
                     /locus_tag="ACZPCR_10385"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008398456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HIR1231308.1"
                     /translation="MCGIVGYIGNKPAAPVLLDGLAKLEYRGYDSAGIAVYDGQKILM
                     EKVKGRLQNLRDLTQDGKNLPGFSGIGHTRWATHGSPSDVNAHPHFNSGGSIAVVHNG
                     IIENYGKLKKMLTEHGYSFRSETDTEVLAHLLDFYYYGKCSRNPLAALIQVMHKAEGS
                     YALGILFQDFPEQVFSARKDSPLIVGSSPEGFFIASDIPAVLPYTRTVYYMDNEEIAV
                     LSADSVHFFNMDEEDIKKESVTVEWDIDAAEKGGYEHFMLKEIYEQPKAVRDTLAPRI
                     HNGRIEIEELQMTDQEISQIKKIMIVACGSAYHTGVTAKYLFEGISRIPAEVDLASEY
                     RYRDPIFQEHTLVIVVSQSGETADSLAALRESKRNGQTTLGIVNVVGSSIAREADKVM
                     YTWAGPEISVATTKAYSAQLAAFYLLALRFAEAKKSISAEEYQELTDSLLKLPQQIEE
                     ILKDRGCIQRFANRYLAAEHIFFIGRGIDYAISLEGSLKLKEISYIHSEAYAAGELKH
                     GTISLIEDGTLVVALATQEQLYPKMVSNIAEVKTRGAFVMALTNENNKDMEQTADYVI
                     KVPKTNRFFANSLAIIPLQLFAYYVSLGRGLDVDKPRNLAKSVTVE"
     gene            8199..8732
                     /gene="rbr"
                     /locus_tag="ACZPCR_10390"
     CDS             8199..8732
                     /gene="rbr"
                     /locus_tag="ACZPCR_10390"
                     /EC_number="1.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008398455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016692 - NADH peroxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin"
                     /protein_id="HIR1231309.1"
                     /translation="MELKGSRTEQNLLTAFAGESQARNKYTYFASVAKKEGYEQIAAI
                     FEQTANNEKEHAKMWFKELHGIGTTPENLKAAAEGENYEWTDMYAAFAKEAEEEGFKE
                     LAVKFRMVAEIEKHHEERYLKLLHNVEMQQVFEKAEETMWECRNCGHLVIGKKAPQVC
                     PVCAHPQSYFEVRKENY"
     misc_binding    8804..9094
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            9203..10234
                     /locus_tag="ACZPCR_10395"
     CDS             9203..10234
                     /locus_tag="ACZPCR_10395"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007871575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HIR1231310.1"
                     /translation="MIQLEHISKSFVTASGTVHAVQDVNLQIGEGEIFGIIGFSGAGK
                     STLVRCINLLERPTEGRVIVDGEDLTAMDLKKLREVRKKIGMIFQHFNLMRSRTVFQN
                     IAFPLKKSGLSKAEKEKKIESLLELVGLSDKKDAYPSQLSGGQKQRVAIARALANDPK
                     VLLCDEATSALDPQTTQSILKLLKQVNETLGITIVLITHEMAVVKDICDRVAIMEQGR
                     VVEEGDTVSVFSHPKEAMTKDFIDTASNLGKIHDLIAEGHSLTEIQPGEQMVLLTYSG
                     SNAGQPLISALAEKFSVSANIIYGNIDYLKGKPLGKLVVTLSGEKEAMDQAIDYIRSL
                     GVEMEVMKR"
     gene            10231..10908
                     /locus_tag="ACZPCR_10400"
     CDS             10231..10908
                     /locus_tag="ACZPCR_10400"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HIR1231311.1"
                     /translation="MSIFYKIAPHLESLGGELLTSLGQTFQMLLVSGIFAFFLGIFFG
                     VLLIVTKRGGIMQNTLLYSLIDKAIDVIRSIPFIILMVLLIPVSRALVGTGSGVKGAY
                     VALIVGTVPFFARQIESVLADVDRGLIEASQAMGFSPVEIIFSVYLKESIPGITRVTM
                     ITFVSLVGITAMAGAIGAGGLGDFAIRYGYQMGYTDMSWVTVIIILIIISIIQFVGNA
                     VIKKTTH"
     gene            10983..11954
                     /locus_tag="ACZPCR_10405"
     CDS             10983..11954
                     /locus_tag="ACZPCR_10405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HIR1231312.1"
                     /translation="MKKVWKKTAVTVTVAAAALALYGCAGSSDTEQTGTAAADKEAEA
                     TVVEVGVVGEYNDQWDTINELLAPENIQVKLVKFTDYAAPNRALADGDIDLNAFQTKT
                     FLDNDMTQKGYDLTVVGDTIIAPLAIYNNKDKISSVSDIKDGDIIAIPNDLTNGGRAL
                     KLLEQAGLIECDPEKGFVPTKADITKYNVEIEIREAESATLANILPDCAAAVINGGNA
                     FTAGLNPVKDSIFTEDVNPDTNEQVPQLVNVIAARTEDKDNEVYQKIVEAYQTPEVEK
                     TIQEAYQGAFLCAWEGAGNAEAEADEAAEETQEIAAEASEETTAAAE"
     gene            12061..13290
                     /locus_tag="ACZPCR_10410"
     CDS             12061..13290
                     /locus_tag="ACZPCR_10410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004180 - carboxypeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HIR1231313.1"
                     /translation="MSKDRQEESGMALKDYVLEQKEYLTSMRQYFHAHPEVSLQEYHT
                     CERIEKELDLAGIPHRRVGETGVYAWIDGKKETADQKKASRIMVLRADIDALAMEDLK
                     TVPYHSENPGVCHACGHDAHVATLLTAARILKSKEAEFSGQIRLFFQQAEEIGAGARL
                     FVQDGLLDGAARVFGAHVSSRLESGKIALTAGPQNASCDYFKIKVTGRGAHVSTPHLG
                     IDAAYVASQIVVNLQSIVARSTNPLETVVVGVGVVRAGTQYNIVAEHAEIEGTTRSFL
                     PEVREFTNRRVREIAEQTARMYGAEAEVEFKDFAAPLINDVQAVKEVTAVTEQLICRE
                     QIVSDYEKALGADDFADYLAVTRGMYAFVGTHSEKKPGSGVAHHHGLFDLDEEALLLS
                     CNVYVDYALWVMEAEEI"
     gene            complement(13287..13559)
                     /locus_tag="ACZPCR_10415"
     CDS             complement(13287..13559)
                     /locus_tag="ACZPCR_10415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantetheine-binding protein"
                     /protein_id="HIR1231314.1"
                     /translation="MDLKALREMGLEQARQIYLDELSDILTDYTERSVPLAPSSRLIE
                     DLGLDSFLTVYFLTQAEERFGIQIDETEYETIVFVQDILDFIFAKG"
BASE COUNT         4027 a         2930 c         3751 g         3267 t
ORIGIN      
        1 ctataaacag gtgagtggac atatattttt aattgtttga ttttcttcta tattataagc
       61 aggtttattt atctattgcg gtatgcagtc tattatatct aattcatgat catcacttca
      121 tcattctcct attatctgat tcatcttatt tcattcaatt caaacattca aatcaatttc
      181 atttctaatg tgaaaggagt atctatgttc agcaaaattg tgagctgcgg tatccgcggc
      241 gtggaaggct atcaggtagc catagaaaca gacatcagca gcggcggtct gccgtccttg
      301 actatggtgg gctatctgtc agaggaggtg cgggaagctc aggaaagagt gagaactgcc
      361 ctgcgaaact ctggttttct tctgccgccc agaagaatta ccatcaatct ttcaccggca
      421 gggctgagaa aggacggtac tgcctttgat ctggctattg cggtatccat tctctgctgc
      481 ctggaggatg aactgtcaaa gacagcttcc caggcggttt ttctgggaga attaggcctg
      541 aatggagaga tcaagccggt caatggaatg atatccaggg tctactgcgc caggcaggcg
      601 ggcttttcca gatgctttgt gcccagggaa aacgtgaagg aaggaactgt ggtggaggga
      661 gtggaaatcg tgggcgtgtc aaacctcctg gagcaggtgg agcttttgag gcatccggat
      721 cgcattaagg gccggtggtt tgacggaaaa agctttgaaa agagtctgaa acagaggaca
      781 gaggcagctg tttccagcca gacgggcgcg gaggaggcag aagccgctgc cttggattat
      841 gcagacatct gcgggcagac tactgtaaaa cgggccatgg aaacagctgc cgccggacgg
      901 cacagctgcc tgctcatcgg ccctgccggg acggggaaaa ccatggctgc cagaaggctg
      961 ccgtccattc tgcctcccat tacattggaa gagagcatag aggtatccaa ggtctacagc
     1021 atatgcggac ttttgccgaa ggatctgcct ttgatcacag agcggccgtt ccgggctcct
     1081 catcacagca tcacggccca gtctctggca ggagggggaa gaaatccaag acctggagaa
     1141 atttctttgg cgtcaggagg cgttctgttc ctggatgagc tgacagaatt tccggggaga
     1201 attttagatc ttctgcgcca gcctttagag gaaaaacgga ttaccgtcac aagactcagc
     1261 ggcattctgg aattcccggc tgactgtatg ctgatctgcg ccatgaatcc ctgcctttgc
     1321 ggaaaatttc cttcagaaaa atgcacctgt tctgaatccc agatacgcag gtatctgggg
     1381 aaggtttccg gccccttttt agaccgcatt gacattggag tggaagttcc ccctgttccc
     1441 tgcggcgaat taagggggac agcccgggcc ggagagaaga gatcagaaga atcctcagcc
     1501 gctatgagaa aacgcgtgga aaaggccaga aacatgcagg aaaagcggtt cgcaggactg
     1561 tccatccgct gcaacagcga gatggggccg gcggaaatca gggaattctg ttccctgctg
     1621 ccggaggacg aggcgtttct gatggccgtt tacaggcagt acggcttcag cgccagaggg
     1681 tttgacaaga ttttgaaggt ggccagaacc gtggcagatt tggacggcgc ggatcagatt
     1741 gggcggatcc atctgtgtga ggctgtttcc taccgaagct ttgagaaaaa atactggggg
     1801 gctaaaaaat gataacagag aaagagtacc tgcactggct gtgccatgtg cctggactga
     1861 aggccgataa gatgaggcgt ctcatggaac aggcaggaag ctttaaggat atctattata
     1921 tgaaggaaca ggaactgaaa tcctgcctgt ttctcactgc cagagaacgg aacgccattt
     1981 tggaactgaa aaaacagctg gatttaacgc gggaggagta tcataggctg aaggaacgca
     2041 gaatagaatt taccaccgtc tttgacagcg gatatccgga acggctgaga aagctgccgg
     2101 gaatgccgct gggcctgttt gtaaaaggga ggatgcctga tgacagccgg ccttccgccg
     2161 ccgttatagg agccagaggc tgcagctact acggaaagga ggaggccaga tacatagcca
     2221 gagagctggc cagatccggt gtgcagattg tcagcggact ggctatggga atcgatgggg
     2281 caggccatgc gggagccctg gaagcggggc aggaaactta tggcgtgctg ggctgcggca
     2341 ttgacatctg ttatccgaag gaaaatttcc ggctgtttga gcggatggag cggcagggcg
     2401 gaatcataac ggagtttttg ccgggcacgc cgccttattc tggaaatttc cccatgcgga
     2461 atcggattat cagcgggctt tctgacttag tcattgtggt ggaggccaga aaaagaagcg
     2521 gatctctgat tacggtaggc tttgccctgg agcaggggaa agaggttctg gccgtaccgg
     2581 gacgggtgac ggatccatta agcgccgggt gcaacgagct gatacagaca ggagcaggcg
     2641 ttctcctgac gccggacgac gccctggatt tactgggtat gaaaagtgaa aaaaatggga
     2701 acattgtgaa aaaacatgaa aatgggcttg tcaagaacga gaaaatggtg tatagttgcc
     2761 tagatttaca accgaagcat ctggaacaga ttgtgacgga aagcgggctg cctgccgggg
     2821 aatgtatggc ggtcctttta aagctggagc tggagagatt tgccgtccag acgtcaaacc
     2881 agtattatgt taggaaattt aagtaggagt tggctatggc taaaaatttg gtaattgtgg
     2941 agtcaccggc aaaggtgaaa acgatcaaaa aatttctcgg ggcaaattat gaggtggacg
     3001 cctccaatgg gcatgtgagg gatatgccca agagccagct gggaatcgac atagagcatg
     3061 actatgaacc caagtatatt acaatccgcg gaaaaggcga tattctggcc aagctcagga
     3121 aagaagtaaa aaaggcagat aaaatttacc tggcaaccga ccctgaccgg gagggggagg
     3181 ctatttcctg gcatctgtct aaggctctta agctggagga ctgtaaggac aaaaaggtat
     3241 acagaattac gtttaatgaa attacgaaaa atgcggtgaa ggcggcgtta aagtctccca
     3301 gagccattga tatgaatctg gtggacgccc agcaggccag acgcgtgctg gatcgaatga
     3361 ttggataccg gatcagcccg cttctctggg caaaggtaaa gagaggactc agcgcaggcc
     3421 gggttcagtc ggtagccctg cgtatgatct gcgaccggga ggaggagatc agttccttta
     3481 tcccggagga atactggaat ctggaggcag atctccgggc caagggatcc agaaagaagc
     3541 tggcggccaa gttttatgga acaagagagg ggaaactgcc tctccgcaca aaagaggaag
     3601 tcgatcaggt cattgaaaat ctggaaggcg cccagtatgt ggtggacgag gtaaagaccg
     3661 gggaacgtgt gaaaaaggct cccattccct ttacaaccag tacgcttcag caggaggcgt
     3721 caaagactct taatttctcc acccagaaaa ccatgcgcct ggcccaacag ctgtatgagg
     3781 gcgtagatat tcagggcaga ggcaccattg gactgatcac ctatctgcgt accgattcca
     3841 cccgtattgc agaggaggcc gacaaggtag ccagggcttt tatcagggaa acctatgggg
     3901 attcctatgt ggccacagag gagacagcca agaagagcag cgctaaaatt caggacgccc
     3961 acgaggcaat ccgtcccaca gatatttccc tgactcctgt tctggtgaaa gaatccctgg
     4021 caagagatca gttccgtctg taccagctga tttggaagcg gtttgccgcc agccgtatgc
     4081 aggccgccgt atatgagact acctctgtcc gcgtagccgc aggagaggag cagggcggat
     4141 atctgtttac cctctccgcc tccaagctga aatttgacgg ctttatgtcc gtctatgtgc
     4201 aggaggagga aaaggaggag aatacggttc tctcggagaa gctggagaaa ggagcagtgc
     4261 tttcctgcga acagctgggc agcagccagc atttcacaca gccgccgtcc cattacacag
     4321 aggcgtcttt agtcaaggct ctggaggaac agggcattgg acgccccagt acctacgcgc
     4381 ctacgatcac gacgattctg gccagacgat atgtggtaaa ggaaaataag aacctttatg
     4441 tgacggagct gggagaggtg gtcaacggaa tgatgaagaa ggcgtttcca agtattgtgg
     4501 atactgcctt tactgcaaat atggagtacc tgctggatcg gattggagac ggcaccgtgc
     4561 cgtggaaaac ggtaattgaa aacttctatc cagatttaga ggaagcagtg acagaggcgg
     4621 agaagaagct ggaggcagtc aagattgccg acgaggtcag cgacgttccc tgcgatctgt
     4681 gcggccggat gatggtgatc aagtatggcc cgcatggaaa attcctggcc tgcccaggct
     4741 ttcctgagtg cagaaacacg aagccttacc tggagaaaat cggcgtagcc tgtccgaagt
     4801 gcggaaaaga gctggtgatc cggaaaacga agaagggacg aaaatattac ggctgcgaga
     4861 ataatccgga atgtgatttc atgtcctggc agaagccttc tccggaagcc tgcccagaat
     4921 gcggcggact gatggtggag aagggcagca agcttctctg catcaatgaa gaatgcggct
     4981 atgtgaagat aaataaaaag cagtctcagg aataggcaga cagaaagcga aaaactgtct
     5041 gaattgctgt aaactgttcc catagaagca gtatgcagaa tagattcacc gaactgtaac
     5101 aaaagaacta ttaaaaaaat tgaaaaaacc agaaaaactc ttgttattaa tcgaaagtcg
     5161 tgttacaatt tatttgagca agcaataatt ttaaaatact aagattaaga aaaggaggta
     5221 actggtaatg agcgttcagt tgttggataa aacaaggaaa atcaataaat tattgcataa
     5281 taatcactcc cataaggtgg tcttcaacga catctgcgaa gtcctcagtg aaatccttca
     5341 gtccaatatt cttgtaatca gtaaaaaggg aaaggttctc ggcgtagcta tctgccctgg
     5401 aattgacgaa attgaggagc tgatcgagga tcaggtaggc ggatttgtgg atcatatgct
     5461 gaatgagaga ctgttaaacg tgctttctac aaaagagaat gtaaatctgg caactttagg
     5521 ctttgcagag gagaatgtaa agaaatatca ggcgattatc acaccgatcg acatgtcagg
     5581 cgagcgtctg gggactttat ttatctataa atcagacgaa cagtatgaca ttgacgatat
     5641 tatcctgagc gagtacggca cgacagttgt gggcctggag atgatgcgtt ctgtaaacga
     5701 ggaaaatgcg gaggagacca gaaagatcca gatcgtgaag tctgctatca gcaccttatc
     5761 cttctctgag ctggaagcaa tcacacatat tttcgacgag ctggagggca gcgagggcat
     5821 cctggttgca agtaagattg cagacagagt aggaattacg agatccgtga ttgtcaacgc
     5881 gctgcgcaag ttcgagagcg ccggcgtgat cgagtcccgg tcttccggaa tgaagggaac
     5941 gtatatcaag gttttaaatg acgtggtatt cgatgaatta aaagctctca aagcggaaaa
     6001 taaataaaac acatttttta atggaaaagg aagaaaaacc ttacctgttc tggcggaacg
     6061 attgggaagg tttttcttcc ttttttcata cctgatttaa ggaaaaacga attttattct
     6121 acagtgacag attttgccag atttctcggt ttatctacgt ccagaccccg tcctaaggat
     6181 acatagtaag caaagagctg aagcgggata atggctaggg aattggcaaa aaatcggttt
     6241 gttttgggaa ctttgattac gtaatcagcc gtctgttcca tgtctttatt attttcattt
     6301 gtcaaagcca tgacaaaggc gcctcttgtt ttcacctctg cgatattgct gaccatttta
     6361 ggataaagct gttcctgggt tgccagagcg acaaccaggg ttccgtcctc aatgagagag
     6421 atcgttccat gcttcagttc cccggcagca tatgcttctg agtggatata ggaaatctct
     6481 ttcagcttca gagaaccttc cagagagatg gcgtaatcga ttcctcttcc gataaaaaat
     6541 atatgttctg cagcaagata ccggttagca aaacgctgga tacaacctct gtccttcaaa
     6601 atttcttcta tctgctgggg aagctttaac aggctgtctg tcaattcctg atattcttct
     6661 gcggaaattg attttttggc ctctgcaaaa cgcagtgcaa gaagataaaa agctgccagc
     6721 tgggcactgt aggctttggt agtggccaca gatatttccg gtccggccca ggtatacata
     6781 actttatccg cctctctggc aatagaactt cccactacgt taacaatgcc cagagttgtc
     6841 tggccatttc ttttcgattc gcgcagcgct gccagagaat cagcagtttc tcctgactgg
     6901 ctcactacaa tgacaagcgt gtgttcctga aaaatcggat cgcggtagcg gtattcagaa
     6961 gctaaatcca cttcagctgg aattcgtgaa attccttcaa agagatattt tgcggtgacg
     7021 cctgtgtgat aggcagagcc gcaggctaca atcataattt ttttgatctg ggaaatctcc
     7081 tgatcggtca tctggagttc ttcaatttct attcgcccgt tgtggattct aggcgcgaga
     7141 gtgtcccgga ctgccttagg ctgttcataa atttctttca gcataaaatg ttcatatccg
     7201 cctttttcag ccgcatcaat atcccactcg actgttacgc tctccttttt tatgtcctcc
     7261 tcatccatgt taaaaaagtg aacggaatct gcggacagaa cggcaatttc ctcgttgtcc
     7321 atataataaa cggttcttgt ataaggaaga acagccggta tgtcggaagc gataaagaat
     7381 ccttccgggc tgcttcctac gatcagagga ctatcttttc tggctgaaaa gacctgttcc
     7441 ggaaaatcct gaaacagaat gccaagagcg taggagcctt ctgccttgtg cattacttga
     7501 attaaagcgg ctaacggatt gcgggaacat tttccataat aatagaaatc cagcagatgc
     7561 gccagcactt ccgtatcagt ttccgaacga aagctatatc catgttctgt cagcattttt
     7621 ttcagctttc cgtagttttc gatgattcca ttatgaacta ccgcgataga accgccgctg
     7681 ttaaaatgcg gatgagcgtt gacatcagaa gggcttccat gagtagccca tcgagtatgc
     7741 ccgatacctg aaaagccggg aagattcttt ccatcctggg ttaaatctct taaattctgc
     7801 aagcgtcctt tgactttttc catgaggatc ttctgtccat cgtaaacagc aattcctgct
     7861 gagtcataac ctctgtattc cagcttggca aggccgtcca gtaaaacagg agcagctggt
     7921 ttatttccga tatatccgac gattccgcac atacttatct ctcctttttg aattaataac
     7981 aaaaattata ataatacctc tgaacatgtc aatatagtta aaaaaaaatt aagaaaatca
     8041 gaagctgttt ttggaagccg aaattcctga atgcatgtaa aatatctgat aacgccagta
     8101 aaaaaatgat aaaagcagaa ttttgttatt gacaaagcag taaaaaaaga ttatgctaaa
     8161 aacagtaata attactataa atagaaggag gagttatcat ggaattaaag ggaagcagga
     8221 cagaacagaa cttattaacc gcttttgcag gggagtctca ggccagaaat aagtatactt
     8281 attttgcgag cgtggcaaag aaggaaggct atgagcagat cgccgctatt tttgagcaga
     8341 cggcgaacaa cgagaaggag cacgctaaga tgtggttcaa ggagcttcac ggaatcggaa
     8401 ccactcctga aaacttgaag gctgccgcag agggcgagaa ttacgaatgg actgacatgt
     8461 acgccgcttt cgctaaggaa gcagaggagg aaggttttaa ggagttagcc gttaagttca
     8521 gaatggtggc agagattgag aagcaccatg aggaaagata cttaaagctg ctccacaatg
     8581 tagaaatgca gcaggtattc gagaaggcgg aggagaccat gtgggagtgc aggaactgcg
     8641 gccacctggt aattggaaag aaagctccgc aggtctgccc ggtatgcgct catccacaga
     8701 gctactttga ggttcgtaaa gaaaattatt aaaaaatagt tgacaaatct gataaatggc
     8761 gttaagatag tcacaacttc agcacagaag tgtttttaat aggaataagg cagagaagag
     8821 aagagtagta gactgaagct tttacagaga gttcccgttt ggtggaaggg aatagagaca
     8881 ggtttatgaa gatggtctta gagccgcata gttgaaataa aaggtgattt tattctgtat
     8941 ccttttattt agactacgac gggatcgccc gttacagcga cagagtataa cctgaaggag
     9001 tctttgatcc ggcaggcgta cttgcagagg cttgccgtgc gagcggcagg taaaattagg
     9061 tggtaccacg ggagcagacg tccccgtcct gatagattga ttacatcagg gcggggtttt
     9121 tttatttcca ggagacattt tggaaaagta aaagcctagc tccgaagcat aacaccacag
     9181 aaaagggaaa ggaagaaaag gcatgattca actggagcac ataagcaaat catttgtgac
     9241 agcatctggg acagtccatg cagtccagga tgtcaatctt cagataggag agggagaaat
     9301 tttcggaatt atcggatttt caggagcagg aaaatctacg ctggtgaggt gcattaattt
     9361 gctggaacgc ccgacagagg gacgcgtcat cgtggacgga gaagatctga cggctatgga
     9421 tttaaagaag ctcagggagg tacgaaagaa aatcggaatg attttccagc actttaatct
     9481 gatgcgctcc agaacagttt ttcaaaacat tgcttttccg ctgaagaaga gcggcctgtc
     9541 aaaggcggag aaggaaaaaa aaatagagag cctattagaa ctggtaggcc tgtctgataa
     9601 aaaggacgct tatccgtccc agctgtcagg cggacagaag cagagggtgg ccattgccag
     9661 agcccttgcc aacgatccga aggtgcttct ctgtgacgag gccaccagcg ccctggatcc
     9721 acagacgacc cagtccatct taaagctgtt aaagcaggta aatgagacgc tgggaattac
     9781 cattgttttg attacccacg agatggcggt ggtaaaggat atctgcgatc gggtggctat
     9841 catggaacag ggacgcgtgg tggaggaagg cgatacggtt tctgtattca gccatccaaa
     9901 agaggccatg acaaaggact tcatcgacac agccagcaat ctgggaaaaa tccacgattt
     9961 aatcgcagag ggacacagcc tgacggagat tcagcccggc gagcagatgg tattgttaac
    10021 ttactcggga agcaatgccg gccagccttt gatttcagct ctggctgaaa aattcagcgt
    10081 cagcgcaaat attatctatg gaaatatcga ttacctgaaa ggaaagccct taggcaagct
    10141 ggtagtgacg ctctccggag agaaggaggc tatggatcag gccatcgatt atatccgctc
    10201 ccttggagta gaaatggagg taatgaaacg atgagtattt tttataaaat tgcgcctcac
    10261 ctggagagcc tgggagggga acttctcaca agcctggggc agacctttca gatgcttctg
    10321 gtatccggaa ttttcgcatt tttcctgggg attttcttcg gggtgctgct gattgtgaca
    10381 aagagaggcg gcattatgca gaacacgctc ttatacagcc tcattgataa ggccattgac
    10441 gtaatccgat ccattccctt cattatatta atggtgcttt tgattcctgt aagccgggcg
    10501 ttggtgggaa ctggttccgg cgtcaaggga gcctatgtgg ccctgattgt gggaacggtt
    10561 ccattttttg caaggcagat tgaatccgtg ctggcagatg tggacagggg cctgatcgaa
    10621 gccagccagg ccatgggctt ttcgccggtt gaaattattt tcagcgtcta tttaaaagaa
    10681 agcattccag gcattacaag ggttaccatg attactttcg taagcctagt gggtatcacg
    10741 gccatggcgg gagccatcgg agccggaggg ctgggtgact ttgccatccg ctacggctat
    10801 cagatgggat atacggacat gagctgggtg acagtcatca ttatcctgat tattatcagt
    10861 atcattcagt ttgtgggaaa tgcagtgatc aaaaaaacca ctcattaaac atgcgggact
    10921 tttaattgta aaaatcaccc tgattcaggg aaatttgata gaagagaaaa ggagaaaaaa
    10981 ttatgaaaaa ggtatggaaa aaaacagcgg tgacagtgac ggtggcagca gcagctctgg
    11041 ccctttacgg atgtgcagga agctctgaca cagagcagac aggcacagcg gccgcagaca
    11101 aagaggcaga ggcgacagtc gtagaggtcg gcgtagtggg cgagtacaac gaccagtggg
    11161 ataccattaa cgagcttctg gcgccggaaa acattcaggt aaagctggta aaattcacag
    11221 attacgcagc tccaaacaga gccctggcag acggagatat tgatttaaac gccttccaga
    11281 cgaaaacctt cctggataac gatatgacgc agaagggcta cgatctgaca gtggtaggcg
    11341 acaccattat tgcgcctctg gctatttaca ataataaaga taagatttct tctgtcagcg
    11401 atatcaaaga cggcgatatt atcgcgattc caaatgacct gaccaacgga ggacgggcgc
    11461 ttaagcttct ggagcaggca ggcctcatcg aatgtgatcc ggaaaagggc ttcgtgccta
    11521 ctaaggccga tatcacaaag tacaatgtgg agatagagat ccgggaggca gaatctgcta
    11581 ctctggccaa cattcttcca gactgcgccg cagcggttat caatggagga aacgcattta
    11641 cagctggatt aaacccagtg aaggactcta tctttacaga ggatgtaaat cctgatacaa
    11701 acgagcaggt tccgcagctg gttaacgtta tcgcagcccg cacagaggat aaagacaatg
    11761 aagtctacca gaaaattgtg gaggcttatc agactccaga ggtagaaaaa accatccagg
    11821 aggcttacca gggcgcattc ctgtgcgcat gggagggcgc tggaaacgct gaggcagagg
    11881 cagacgaagc ggctgaagaa actcaggaaa ttgcagccga ggcttccgag gaaactacgg
    11941 cagcagcaga atagccagga gatgtgaaca ctgaagccgg aacgagttca gaataaaata
    12001 gcgaaacagt aatatccgta tcattttcgg ggcctgaaca ctcaaaggag acaggcctct
    12061 ttgtcaaagg acagacagga ggaaagcggc atggcgttaa aggattatgt attagaacaa
    12121 aaagaatatc tgaccagtat gagacagtat tttcacgctc atccagaggt gagcttacag
    12181 gaatatcata cctgtgagcg gattgaaaaa gagctggatc tggcaggaat tccccacaga
    12241 agagtgggag agactggagt gtacgcctgg atagacggaa aaaaagagac cgcagatcag
    12301 aaaaaggcgt cccgcatcat ggttttgaga gccgatattg acgctctggc tatggaggat
    12361 ttaaaaacag ttccttacca ttccgaaaat cctggcgtat gccacgcctg cggccacgac
    12421 gcccatgtag ccactcttct gacagcagct aggattctga aatcaaaaga agcagaattt
    12481 tccggccaga tccgcctgtt tttccagcag gcagaggaga taggagcggg agcccgcctc
    12541 tttgtgcagg acggactgtt agacggtgcg gccagagtat tcggcgctca tgtatccagc
    12601 cgtctggaaa gcggaaaaat cgctctcaca gcaggtccac agaacgccag ctgcgactac
    12661 tttaaaatca aggttacagg gcggggcgct catgtatcca ctccccatct gggaatcgac
    12721 gcggcctatg tcgcctcaca gattgtggta aatctgcaga gcattgtggc cagaagcacg
    12781 aatccgctgg aaacggtagt ggtaggagtg ggagtcgtcc gggccggaac ccagtacaat
    12841 atcgtagcgg aacatgcgga gatcgaggga accaccagaa gcttccttcc ggaagtcaga
    12901 gaatttacaa acaggagagt cagggaaatt gctgagcaga ctgcccgtat gtacggggcg
    12961 gaggcagaag tggaatttaa ggatttcgca gctcctctga ttaatgatgt gcaggctgtc
    13021 aaagaggtga cggcagtaac agagcagctg atttgcagag agcagattgt gagcgattat
    13081 gagaaagctc tgggagccga cgatttcgcc gattacctgg cagtaaccag gggaatgtac
    13141 gcctttgtgg gaacccacag cgaaaagaag ccgggaagcg gagtggccca ccatcacgga
    13201 ctgtttgacc tggatgagga agcgcttctc ttatcctgca acgtgtacgt ggactacgcc
    13261 ttgtgggtga tggaggcaga ggaaatttaa ccttttgcaa aaataaaatc taaaatatcc
    13321 tgaacaaata caattgtttc atattccgtc tcatcaatct ggatgccgaa ccgctcctct
    13381 gcctgagtga gaaaatagac agtcagaaaa gaatcaagcc ccagatcctc gatgagacgg
    13441 gaggaggggg caaggggaac ggaacgttcc gtatagtctg taagaatgtc agacagctca
    13501 tccaggtaga tctgtctggc ctgttccagg cccatttccc tgagtgcttt taaatccatg
    13561 aattttgtct ccttttagaa taaatcatgt atatatgaga gaaaaagtgt cgctttatag
    13621 atagttaagc gacacttttt gccagaggcc cttatccgtt atttcgttat aaaaaatgga
    13681 atctttgccg ggaacgaatt taaaataaaa ttaaataggg aaaattcaga cttttaataa
    13741 aaaaacaaga aaaatttaga agtaaatgaa atatgtgcct gctgatagca attgactccc
    13801 ctttgaaaga atgctataat ctacaggaac ataaatgaat aataaaaatt atgcggattt
    13861 attattataa tagtaaaaaa gtgtcgctta actatctatt aagcgacagg aaaatgtata
    13921 aaaggaggag ggctggctta tgagctggta cgtcctgcag tgcagagttg gacag
//
LOCUS       DBMDUW010000064        13218 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_2473_length_13218_cov_2.936190, whole genome shotgun sequence.
ACCESSION   DBMDUW010000064 DBMDUW010000000
VERSION     DBMDUW010000064.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 13218)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 13218)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13218
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2473_length_13218_cov_2.936190"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..958
                     /locus_tag="ACZPCR_10420"
     CDS             <1..958
                     /locus_tag="ACZPCR_10420"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015554842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="pyruvate carboxylase subunit B"
                     /protein_id="HIR1231315.1"
                     /translation="GDAYTLDYWMEMAKRVEDMGADSLCIKDMAGLLTPYAAEELVTA
                     LKESTKLPIDLHTHYTSGVASMTYLKAVESGCDIIDTAISPFALGTSQPATEVMAETF
                     SGTPFDTGLNKEALAEIADYFRPMREEALKSGLMNTKVLGVDINTLRYQVPGGMLSNL
                     VSQLKEAHAEDKYYDVLQEIPRVRKDFGEPPLVTPSSQIVGTQAVLNVLMGQRYKMFT
                     KESKKLLMGEFGQTVKPFNPEVQKKAIGKAEPITCRPADLIEPQLQKLEAEMSQWKTQ
                     DEDILTYALFPQVAKEFFEYREAQNTGIDPKAADKTNKAYPV"
     gene            1114..3699
                     /locus_tag="ACZPCR_10425"
     CDS             1114..3699
                     /locus_tag="ACZPCR_10425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004462259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HIR1231316.1"
                     /translation="MKKSRYKKGMAFLLSCVLAFGTCVSVLDPSFSLRTFAYAEKQGT
                     IIASSLNVRSGPGTGNASIARLANGTAVTVIGEDTASDGVLWYKIRFTGSGGAQTTGY
                     VSSHYVKLASQNIVSDSNFEAYMTQQGFPESYKQGLRELHSKYPKWKFTALQTGLDWN
                     TAVTEESKVTRNLVARSSISSWKSTEDGAYDWATGTWPGFDGSSWVAASRDIISYYMD
                     PRNFLNETYIYQFMNQSYDPSIHTREGLVTMVEGTFLSGTAPAGGASGSRGGSGSGSS
                     SGSPSGPDGGSSDSGSAPGGSPDGGEITPGQMGGPGASLGTSGRYVQINENSWSISSH
                     LVDTVSSYGPGMDSENSVPGGAPGAEQQPGSGDTGGSAGRPYVDIIMDAAAQSGVNPY
                     ILASMILVEQGKQGTGRSISGTVSGYTGYYNFFNIEAYQSGSMDAVTRGLWWASQSGS
                     YGRPWNSREKSIIGGAKWYGNNYPGRGQNTLYLKKFNVQGSNPYTHQYMTNIQAAASE
                     GAELAKISSLKNTALEFSIPVFKNMPEGPCAQPTLDGSPNNKLSGLGVDGFALTPSFN
                     RDTQSYDLIVDPSVSSVTISASAIDSKASVSGTGTVNLQSGNNDITIAVKAENGHVRN
                     YVIHVVRQDNGPTYSESIGGGVTPGGTTGPGGGSGPGGDTTVEIVGPPGSSQPGGSGT
                     SAPGSSAPGSGNSVPGPIAPDGSVEGFGTEESGGALQEPGSGTHSQKPGESKGTRVVT
                     AGTSVQALAAQIQSEKAGTSVKIYTSSGNEASGSAATGYLAQAYDSKGDAVLKQTVIV
                     RGDNTGDGKVNVLDILNAQRHILGLGSLKGEFAAASDVNGNGKIDITDILAMQRDVLG
                     IEKLK"
     gene            3794..5728
                     /locus_tag="ACZPCR_10430"
     CDS             3794..5728
                     /locus_tag="ACZPCR_10430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008396008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadherin-like beta sandwich domain-containing
                     protein"
                     /protein_id="HIR1231317.1"
                     /translation="MAAAFIMALTPFQAETVFAATAKITFNDPKPEVGTEFTVTVKAS
                     TADGNLGGADIVLSYDPAVIEFVSGNNANGGAGTVRLVGTMDSASTKSFDFNLKFKAV
                     QAGSTQISVSSSEFYDSDMQAMTMSHSGSSSVQVQAPASYSSEASLASLKISPGGISP
                     AFSPDVTSYTASVGADVSKIAVSAERKDPKSKLVVSGDSNLQPGENKVVCKVTAEDGK
                     TVKNYTITVTRAAAGETQAPSESGEEETQAAVLGELKTEIEGKEYLVAASFDQSLLPA
                     GFTASTVTYQEQDIMGGENGDLTILYLQDPEGSEGFWFYDAESGEFTRYANIHVSEKN
                     ITVLPADEAPEVPEGFAETTIQLNGDYKVEGWVWESDTEQRYCVVYGMNENGEKGLYR
                     YDIGEKTIQRYFEDPAVKSSYSDEEVEAFIQEYNDMNQLYRLRLIIIIALGAVCVILI
                     IMVIVLLRKKAGGNGSDHPHDPGVQNPGGSRRQPDALAQPSAGKSRQREVRTEHSENR
                     PERREAAAERPERVKPSGRPVSQGRESRRTEREPRPERDRTTSPRAERPQEERREQKR
                     PVREAESRTEGRRNTRLQGQPPVRRESEPRVQRPRDSRPASHSPQSRNRMPASGTAEA
                     SAKQAERRRKDEIDFLDLDD"
     gene            5909..6295
                     /locus_tag="ACZPCR_10435"
     CDS             5909..6295
                     /locus_tag="ACZPCR_10435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007712354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HIR1231318.1"
                     /translation="MVLEIDFNSDEALYIQLRNQIIVGIATERIREGDSLPSVRQLAE
                     HIGINMHTVNKAYSVLKQEGLVKLDRRRGAVICLDVDKMRAVEEMKRDLGVVLARGCC
                     KRISRSEVHELVDSIFDAFADNGGSC"
     gene            6360..6914
                     /locus_tag="ACZPCR_10440"
     CDS             6360..6914
                     /locus_tag="ACZPCR_10440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007712352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HIR1231319.1"
                     /translation="MLCERCKIREANIKYTEVINGVKTEHNLCSQCAKELDFGQYSAV
                     FDGEFPLGRLLSGLLGLEGASAEEENRQEIACPTCGTTYEAFIDKSRFGCPDCYRVFD
                     LLIGEKIKKMQGNDSHTGKRPKFQVEEKDTHVESDGELKLSKEEEIRGLERKLREALR
                     FEEYETAAKCRDEIRALKAEDEDE"
     gene            6907..7941
                     /locus_tag="ACZPCR_10445"
     CDS             6907..7941
                     /locus_tag="ACZPCR_10445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP--guanido phosphotransferase"
                     /protein_id="HIR1231320.1"
                     /translation="MSRWFEEVKNENSSIVASRIRLARNWEEYRFPGSLTPEEAREMI
                     SRLKKELRGLPDQEGKDCEYLDLERMPDLERRALRERRLINRSMAEKKTPGGLILSDD
                     ERISLMLNGDDHIRIQVMEQGLSLKECYEKADCLDNYINERIPYAFNEKYGYLTTYPT
                     NVGTGLKASVIVHLPTLSLSKKFQDLLGDMGRFGAVVRGLHGRPGENGGDLYEVTNQK
                     TLGLSEKEILELVENVAVQLTDQEAQVRKMALEKQRLMIEDEVYKAYGVLRYARRLAV
                     KDAQTFLSHVRAGVSDGLLRFKEPCSLYGLMVKIQNANLQKNSSRPLGKEELEMARAA
                     CIRAYLPEIE"
     gene            7977..10496
                     /locus_tag="ACZPCR_10450"
     CDS             7977..10496
                     /locus_tag="ACZPCR_10450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HIR1231321.1"
                     /translation="MIDRFTEKAREAIQAAAELAAQLDHGYVGTEHLLLGLIREGTGV
                     AAMILGHYGVTEEKVLSLMERLISPASPTRVQGELEYTPGARQMLEASYEEAVLFKAP
                     LIGTEHILIAMIKNGKCTAARLLNTMNVNIQKLYVDLLNAMGDDAPADREELTGKTKK
                     EKGETPNLDHFSRDLTQMAREGKLDPVIGREAQMRRVIQILSRRTKNNPCLIGEPGVG
                     KTAVAEGLAQMIVNGDVPETIAGKRLVSLDLSGMVAGSKYRGEFEERIKKVLAEIRED
                     GNVLLFIDEIHTIIGAGGAEGAIDASNILKPSLARGELQLIGATTVEEYRKYIEKDAA
                     LERRFQPVMVEEPSEKESVEILKGLRSCYEEHHKVEITDEALEAAVKLSARYINDRFL
                     PDKAIDLIDEASSKIRLTVYTEPEEIKLLEEEIKTLEEEKEEAIREEAYEKAGDIKKQ
                     QEKRQKKIEEIRAVWQEEKQKRKLSVGENEVADVVSQWTKIPVKKLSEGESERLLKLE
                     GVLHERVVGQNEAVCAVAKAIRRGRVGLKDPKRPIGSFLFLGPTGVGKTELSKALCGA
                     MFGTENAMIRVDMSEYMEKHSVSRMIGSPPGYVGYDEGGQLSEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGHITDAQGRKIDFKNTILIMTSNAGAENIISPKRLGFASEN
                     DEKANYNFMKDRVMEEVKRLFRPEFLNRIDDIIVFHPLNMENIREIAGIMTASIAGRT
                     KEQMNIALTVDSSARDYLAEKGYDEKYGARPLRRTIQTMIEDRLAEEILAGTFKSGDT
                     VAVKKGKEGLIFSKKVKRASARKAAGKTEKSSGFLTGTVIE"
     gene            10532..10945
                     /locus_tag="ACZPCR_10455"
     CDS             10532..10945
                     /locus_tag="ACZPCR_10455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endosialidase"
                     /protein_id="HIR1231322.1"
                     /translation="MPVVNELIRIEDDGTISFGNYKLTEKSKLDNFEYKGDLYKVKTH
                     DEITKLERNGLFVYESVPGTAVSHFAVDDTTVKFSVEGAKDAQVTLQLEDDCEYEVFV
                     DGAAVGGMKTNLSGKLVVSVELNQGEAAQIKVTKR"
     gene            11066..12475
                     /gene="radA"
                     /locus_tag="ACZPCR_10460"
     CDS             11066..12475
                     /gene="radA"
                     /locus_tag="ACZPCR_10460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HIR1231323.1"
                     /translation="MAKAKTTIFFCSECGYESAKWTGQCPACRAWNTMVEGLAEPVSK
                     AKAPRGGLTCAEPAGGLAGRNRAFQEVTPKSLSEIELENEDRADTGFGELNRVLGGGA
                     VKGSLVLVGGDPGIGKSTILLQVCRNLAERGQKVLYISGEESLKQIKLRASRIGQMKE
                     SLCFLCETNLEVIQAVVKRTSPDTVVIDSIQTMFMEDVSSAPGSVSQVRECTNALLQI
                     AKGLGITIFIVGHVTKEGVVAGPRVLEHMVDTVLYFEGDRHASYRILRGVKNRFGSTN
                     EIGVFEMREEGLAEVKNPSEFMLEGRPAGASGAVAACSIEGTRPMMVEVQALVTRTNF
                     GMPRRTAAGADYNRVNLLMAVLEKRCHYDLGQMDAYVNIAGGMKMNEPAMDLAIVMAL
                     ISSYKDRPLDEKTAVFGEVGLSGEVRSVSMAEQRVNEAVKLGFEACILPQICLNKMKK
                     RTDIRLIGVSSVKEAVAAL"
     gene            12660..12730
                     /locus_tag="ACZPCR_10465"
     tRNA            12660..12730
                     /locus_tag="ACZPCR_10465"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12692..12694,aa:Trp,seq:cca)
BASE COUNT         3740 a         2858 c         3936 g         2684 t
ORIGIN      
        1 aggagatgct tataccttgg attactggat ggaaatggca aagagagtag aagacatggg
       61 tgctgattcc ttatgtatta aggatatggc aggactttta actccatatg cggcagaaga
      121 gcttgtaact gctctgaagg aatctaccaa gcttccgatt gatctgcata ctcactacac
      181 gtctggcgtg gcttctatga cctacttaaa ggcagtggaa tccggctgcg atattatcga
      241 cacggctatc tccccatttg ccctgggaac aagccagccg gctaccgagg taatggcgga
      301 gaccttcagc ggcactccgt ttgacacggg acttaataag gaagctctgg cagagatcgc
      361 agattacttc cgtccgatga gagaggaagc attaaagagc ggcctgatga atacaaaggt
      421 tctgggcgta gatatcaaca cgctgcgcta ccaggttccg ggaggcatgc tctccaacct
      481 ggtttcccag ttaaaggagg ctcacgcaga ggacaagtac tacgacgtgc ttcaggagat
      541 tccgagagtc cgcaaggact ttggagagcc gccgcttgta actccttcct cccagattgt
      601 gggaacccag gctgtgttaa acgtgctgat gggacagaga tacaagatgt ttaccaagga
      661 gtccaagaag ctgctgatgg gagaattcgg ccagactgta aagccgttta atccggaggt
      721 tcagaagaag gctattggaa aggcagagcc aatcacctgc cgtccggctg acttaatcga
      781 accgcagctt cagaagctgg aggcagagat gtcccagtgg aagacacagg acgaggatat
      841 cctcacctac gccctgttcc cacaggttgc caaggagttc ttcgagtaca gagaagctca
      901 gaatacagga atcgatccga aggcagcaga caagacaaat aaagcatatc ctgtataaaa
      961 agcaggaaaa agggccagat gcagagattg acgctgcacc tggccttttt ctcttgaaat
     1021 cttttcagac aggaacgccg tgtctgaaat tagttgacat ggaacggctc ttgtcattat
     1081 aatgaagata ttgccaaaat aggagataca tagatgaaaa aatcaagata caaaaaagga
     1141 atggcatttc ttctgagctg cgtactggct tttggaacct gtgtcagcgt tctggatccg
     1201 tcgttttccc tgagaacctt tgcctatgcg gaaaagcagg gaacaattat tgcttccagc
     1261 ctgaatgtga gaagcgggcc gggaacggga aatgcatcca ttgccagact ggctaacgga
     1321 acggctgtga ctgtgatagg agaggatacg gcttctgacg gcgtactttg gtacaaaatc
     1381 aggtttacag gaagcggggg agcccagacg acaggatacg tatccagcca ctatgtcaag
     1441 ctggcttccc agaatattgt gtcggacagc aatttcgagg cttatatgac gcagcagggc
     1501 tttccggaga gctacaagca gggactgaga gagcttcact ctaaataccc caagtggaag
     1561 tttacggctc tgcagacagg gcttgactgg aatacagctg tgacggagga gagcaaggta
     1621 accagaaacc tggtggccag aagcagtatt tcctcctgga aatcgacaga ggatggagcc
     1681 tacgactggg ccaccggaac gtggcctgga tttgacggca gttcctgggt ggcagcgtcc
     1741 agggatatta tcagctatta catggatccc agaaatttct tgaatgagac ttacatttac
     1801 cagtttatga accagtccta cgatccgtcg attcacacca gggaaggcct ggtgacaatg
     1861 gtggagggca ccttcctcag cgggacggct cctgctggag gcgcatctgg cagcagggga
     1921 gggtctggca gcggcagttc ctcgggcagt ccttcaggac cggatggcgg ctcttctgac
     1981 tccggcagcg cgccaggagg aagccctgac ggcggcgaga ttactccggg acagatggga
     2041 ggcccaggcg cttctctggg gacttcagga agatacgtcc agataaacga gaactcatgg
     2101 tctatttcca gccatctggt agatacagtt tcctcctatg gaccgggtat ggattcagaa
     2161 aactcggttc ccggcggagc gccaggagcg gagcagcagc cgggaagcgg ggataccggc
     2221 ggttcagccg gcaggccgta tgtagatatt attatggatg ctgcggccca gtcaggcgtt
     2281 aatccctata ttttagcgtc catgattctg gtagagcagg gaaagcaggg aacgggaaga
     2341 agtatatcgg gaacagtttc aggctataca ggctactaca atttttttaa tatagaagcg
     2401 taccagtcag gctctatgga tgcggtgaca agaggactct ggtgggcgtc tcagtccggt
     2461 tcctacggaa ggccgtggaa cagccgtgag aagtccatta tcggaggcgc caagtggtat
     2521 ggaaacaatt atcctggacg cgggcagaac accctctacc tgaagaagtt taacgtgcag
     2581 ggaagcaatc cctataccca ccagtatatg actaacattc aggcggcagc ttccgaggga
     2641 gcggagcttg caaagatcag ctctctgaaa aatacggctc tggaattttc tattcctgta
     2701 tttaaaaata tgccggaagg cccctgcgcg cagccaacat tagacggaag ccccaataat
     2761 aagctgtccg gtctgggagt agacggcttt gccttaacgc caagctttaa cagagatacg
     2821 cagtcctatg acctgattgt agatccgtct gtcagcagcg tcacaatctc tgcatctgcc
     2881 attgattcca aggccagcgt cagcggtacc ggaacggtaa atctgcagag cggaaataat
     2941 gatattacga tagcggtgaa ggcagaaaac ggccatgtac gcaattatgt gatccacgtg
     3001 gtgagacagg acaacggtcc aacctattca gaatccattg gaggaggcgt gacgccggga
     3061 ggaaccacag gccctggagg aggttctggc cctggaggcg acacgacagt agagattgtc
     3121 ggtccaccgg gaagttccca gcccggcggc tccggaacca gcgccccagg ttcttctgcc
     3181 cccggatctg gaaactctgt gccagggcct atcgccccgg atgggagcgt agagggcttc
     3241 ggcacagagg agtcaggcgg cgcgcttcaa gagcccggtt ccggaactca cagccagaaa
     3301 cctggtgaaa gcaaaggaac cagggtggta acggccggaa ccagcgtcca ggcgctggcg
     3361 gctcagatcc agtcggagaa agcagggact tctgtaaaga tttacacttc ttccggcaat
     3421 gaggcctctg gcagcgctgc tacagggtac ctggctcagg cctatgattc aaagggagac
     3481 gctgttttaa agcagaccgt tattgtccgg ggcgacaata ccggagacgg aaaggtgaac
     3541 gtccttgata ttttaaatgc ccagcgccat attttaggac tgggctcttt aaagggagag
     3601 tttgcagcag cctccgatgt caacggaaac ggtaaaattg atattacgga tattcttgcc
     3661 atgcagagag acgtgctcgg aattgaaaag ctgaagtagc agcgtttaag tccggcggca
     3721 gcatgcagca gaatatggac agaaacagac gggagaacgc atgaacagaa caatcagaca
     3781 atttttcata tgcatggccg cggcatttat catggccctg acgccgttcc aggcggagac
     3841 tgtttttgcc gcgacagcga aaattacttt caatgatccg aaaccagagg tgggaacgga
     3901 gttcaccgtg acggtgaagg cttccacagc tgatggaaat ctgggaggag cggatatcgt
     3961 tctttcctat gatccggctg tgatagaatt tgtcagcgga aataatgcca acggaggcgc
     4021 gggaactgtc cggctggtgg gaaccatgga ctctgccagt acaaaaagct ttgattttaa
     4081 cctgaaattt aaagcggttc aggcgggaag cacgcagatc agcgtcagca gttcagaatt
     4141 ttatgattca gatatgcagg ctatgacgat gagccattct ggaagctcct ccgtgcaggt
     4201 tcaggcacct gccagctatt caagcgaagc ttctctggct tccctgaaaa tctctcccgg
     4261 aggaatttca ccggcctttt cgccggatgt gacgtcctac acggcgagcg tgggggcgga
     4321 cgtaagcaaa attgcagtca gcgcggagcg caaggatcca aaatcgaagc tggtcgtgtc
     4381 aggagacagc aatctgcagc caggagaaaa caaggtagtc tgcaaggtga cggctgagga
     4441 tggcaaaacg gtaaagaatt atacgattac tgtgacgaga gcggcggccg gggagacgca
     4501 ggctccttct gaaagcgggg aagaggagac gcaggctgca gttttaggag aactgaaaac
     4561 tgagatagaa ggaaaagagt atctggtggc agcctccttt gatcagtccc ttctgcctgc
     4621 aggctttacg gcgtccactg tcacttacca ggagcaggat attatgggcg gcgaaaacgg
     4681 cgatctgacc atcctgtatc tgcaagatcc ggaaggcagc gagggcttct ggttctacga
     4741 cgcagagtca ggggaattta cccgctacgc caatatccat gtgagcgaga agaatatcac
     4801 agtgcttccg gcagacgagg cgccggaggt tccggaaggg tttgcagaga caaccattca
     4861 gctgaacgga gattacaagg tagaaggctg ggtgtgggaa agcgatacag aacagagata
     4921 ctgcgttgtc tacggaatga acgaaaacgg agaaaaggga ctgtaccgct acgatatcgg
     4981 agagaagaca attcagagat attttgagga tcctgctgtt aagagctcct attcggatga
     5041 agaggtggaa gcctttatcc aggaatacaa tgacatgaac cagctgtacc gcctgcgtct
     5101 cattattatc atagccttag gagcggtgtg cgtgattctt attatcatgg taatcgttct
     5161 tttaaggaaa aaggcaggcg gaaacggctc cgatcatccc catgatccgg gcgtccagaa
     5221 tcctggcgga agcagacggc agccggacgc tttggcgcag ccatctgccg gaaagagccg
     5281 ccagagagag gttcggacag aacacagtga aaacaggccg gaaagacgcg aagccgcagc
     5341 agagcgtccg gagagggtga agccatccgg ccgtccggtt tctcagggca gggagagccg
     5401 cagaacagaa agagaaccga gaccggagcg ggacagaaca acttccccga gagcagaacg
     5461 tcctcaggag gagagaaggg agcagaagcg tcctgtaaga gaggctgaat ccaggacaga
     5521 aggcagaaga aatacccgtc tccagggaca gcctcctgtg cggagagaat ctgaaccaag
     5581 agtgcagagg cccagagaca gccgtcctgc ttcccacagc ccgcagtcca gaaacagaat
     5641 gcctgcgtct ggaacagcag aagcttcagc aaagcaggca gagagacgca gaaaagatga
     5701 gatagatttt ctggatcttg acgattaagt aattcaggaa agacaggagt ggttcctgtc
     5761 cggaagcagg ccgcagccag tgcagagaaa gcgcatggca gcggcctgtt ttgccgtact
     5821 gcaaagaacg caggaggaaa agacttgacg gaacgatttg gaatgttata tactcgatat
     5881 aacagatata acgaaagatg gtgagcctat ggtattggaa attgacttta acagcgacga
     5941 ggccctttac attcagctga ggaatcagat catcgtcgga attgccacag agcgtatcag
     6001 ggagggagat tctctgcctt ctgtgcggca gctggcggaa cacatcggca ttaacatgca
     6061 tacagtgaat aaggcatatt ctgtattaaa gcaggaaggg cttgtgaagc tggatcgcag
     6121 aaggggcgct gttatctgcc ttgacgtgga taagatgcgg gcggtagagg agatgaaacg
     6181 ggacttaggc gttgttttgg ccagaggatg ctgcaagcgc atcagccggt cggaggtcca
     6241 cgagctggtc gactccattt tcgacgcgtt tgcagataat ggaggcagct gctaggcagc
     6301 aggattctga cgaaattccg gcgcatcggc caggaaggaa aagccatgga ggatgaaata
     6361 tgttatgtga gagatgtaaa atccgagagg cgaatatcaa atatacagaa gtgattaacg
     6421 gggtaaagac agagcataat ctgtgctccc agtgtgcgaa ggaactggat ttcggccagt
     6481 actccgctgt ttttgacgga gaatttcctc tgggcaggct gctgtccggc cttctggggc
     6541 tggagggagc ttccgccgag gaggagaaca gacaggagat tgcatgtccc acctgcggca
     6601 cgacctatga agcgtttata gacaagagcc gtttcggatg ccccgactgc tatcgcgtat
     6661 ttgatcttct tatcggagaa aagattaaaa agatgcaggg aaatgacagc catactggaa
     6721 agcggcccaa attccaggta gaagaaaaag atactcatgt agagagcgat ggcgagctga
     6781 agctttcaaa ggaagaggaa atccgggggc tggagcgaaa gctcagagag gctctgcgtt
     6841 tcgaggaata tgagacggcg gcgaaatgcc gggatgagat ccgggccctg aaagcggagg
     6901 atgaggatga gtagatggtt tgaggaagta aaaaacgaaa actccagcat agtggcaagc
     6961 cgcatccggc tggcgagaaa ctgggaggag taccggtttc cgggaagcct gactcctgag
     7021 gaagcgaggg agatgatctc caggctgaaa aaggaactga gaggactgcc ggatcaggag
     7081 ggaaaggact gcgaatacct ggatttggag agaatgcctg atttagagcg cagagcgctc
     7141 agagagaggc gtctgattaa cagaagcatg gcagaaaaaa agacgcccgg cggcctgatc
     7201 ctctcagatg atgagagaat cagcctgatg ctgaacggcg acgaccacat cagaatccag
     7261 gtaatggagc aggggctgtc gctaaaggaa tgctatgaga aggcagattg cctggataac
     7321 tatattaatg aaagaattcc atacgcattc aatgagaaat acggatattt gacgacttat
     7381 cccactaatg tgggaacagg actgaaggcg tcggtgattg tccaccttcc cacgctgtcc
     7441 ctgagcaaga agtttcagga tctgctggga gatatgggac ggtttggagc agtggtcaga
     7501 ggccttcacg gaaggcctgg ggaaaacggc ggagatctct atgaggtaac gaaccagaag
     7561 acgctggggc tgtcagaaaa ggagattctg gagctggtag aaaatgtggc ggtgcagctg
     7621 acggatcagg aggcgcaggt cagaaagatg gctttggaga agcagcgcct gatgatagag
     7681 gatgaggtct ataaggctta cggtgttctg cgctatgcca gaagactggc ggtaaaggat
     7741 gcccagacct ttctgtctca tgtgagagcc ggtgtgtctg acggcctgct ccgttttaag
     7801 gaaccctgct ccctctacgg cctgatggtg aaaatccaga atgcaaatct tcagaaaaat
     7861 tccagcaggc ctcttggcaa ggaagagctg gagatggccc gggcggcctg tatcagagct
     7921 tatctgcctg aaatagaata gaaaaagaac atggtataca ggaggaatga aattatatga
     7981 tcgatcgttt tacagagaag gccagagagg cgatccaggc ggcggcagag ctggccgctc
     8041 agctggatca cggctatgtg ggaacagaac atctgcttct cggccttatc agagaaggga
     8101 caggtgtcgc tgccatgatt cttggacact acggagtgac agaggaaaag gtgctgtctc
     8161 ttatggaacg tctcatttct ccggcttccc cgacgagagt gcagggagag ctggagtata
     8221 cgccgggagc cagacagatg ttggaagcca gctatgagga ggcagtgctg tttaaagcgc
     8281 cgttaattgg aacggagcat attttaatcg ccatgattaa aaacggcaag tgtacggcag
     8341 ccagactttt aaatacaatg aatgtgaaca ttcagaagct gtatgtggat ctgctcaacg
     8401 ctatgggcga cgacgctccc gccgaccggg aggagttaac gggaaagacg aagaaagaga
     8461 agggggaaac tccgaatctg gatcacttca gccgcgactt aacccagatg gccagagaag
     8521 gaaagctgga tccagtcatt ggaagagaag cccagatgcg ccgggtgatt cagattctga
     8581 gcagacgtac caagaataac ccctgcttaa tcggagagcc gggagtagga aaaacggcag
     8641 tggcggaagg gctggcccag atgattgtaa acggcgacgt gccggagacc attgccggaa
     8701 agcgactggt aagcctggat ctgtccggca tggtggcggg cagcaaatac agaggcgaat
     8761 ttgaagagag aatcaaaaag gttctcgccg agattcggga ggacgggaat gtgcttctct
     8821 ttatagacga gattcacact attatcggag ccggaggagc agaaggggcc atcgacgcct
     8881 caaacatttt aaaaccgtca ctggccagag gagagcttca gctgatagga gccactacgg
     8941 tggaggagta caggaagtac attgagaagg acgctgccct ggaacgacgc ttccagcctg
     9001 tgatggtgga ggagccgtcg gagaaggagt ctgtagagat tttaaaaggc ctgcggagct
     9061 gctacgagga acaccacaaa gtagagatta ccgatgaggc cctggaggcg gcggtcaagc
     9121 tgtccgcccg gtatatcaac gatcgcttcc ttccggataa agcgattgat ctgattgacg
     9181 aggcgtcctc caagatccgt ctgaccgttt acacggagcc agaggagatt aagcttctgg
     9241 aggaggagat taagactctg gaggaggaaa aagaggaggc tatccgggag gaagcctacg
     9301 aaaaagccgg agatatcaaa aagcagcagg aaaaacgaca gaaaaagata gaggaaatcc
     9361 gcgccgtatg gcaggaggag aagcagaaga ggaaactgtc tgtgggggaa aacgaggtgg
     9421 cggacgtagt ttcccagtgg acgaagattc cggtgaaaaa gctgtcagag ggagagtctg
     9481 agaggctgct gaagctggag ggagtgctcc acgagagagt ggtggggcag aacgaggcag
     9541 tctgcgcagt agccaaggcc atccggagag gcagggtagg actcaaggat ccaaagcggc
     9601 ctatcggctc cttcctgttt ttaggaccta ccggagtggg caaaacagag ctttccaagg
     9661 ctctctgcgg ggccatgttc ggcacggaga acgccatgat ccgcgtggat atgtcggaat
     9721 acatggaaaa gcacagcgtt tccagaatga ttggttcccc gccaggatat gtgggatacg
     9781 atgagggagg ccagctgagc gaaaaagtga gaagaaatcc ttactctgtc attttatttg
     9841 acgagattga gaaggcccat ccagacgtat tcaatattct tctgcagatc ctggacgatg
     9901 gccatattac cgacgcccag ggcaggaaga tcgactttaa aaatacgatt ctcattatga
     9961 cttccaacgc gggagcggaa aacatcatct ccccgaagcg gctgggattc gcctccgaaa
    10021 atgatgagaa ggcaaactac aatttcatga aagacagggt gatggaggag gtaaagcgtc
    10081 tgttccgtcc ggagttttta aacagaattg acgatatcat tgtcttccat ccgctgaaca
    10141 tggaaaatat cagggagatt gcaggcatca tgacagcttc catcgcggga agaacgaagg
    10201 agcagatgaa cattgccctt actgtggaca gcagtgccag agattatctg gctgagaaag
    10261 gctacgacga gaaatacggc gcaagacctc tcagaagaac catccagact atgattgaag
    10321 accggctggc agaggaaatc cttgcgggaa cctttaagag cggagatacg gtagccgtga
    10381 aaaagggaaa agaagggctg attttttcta aaaaagtgaa gagagcctca gccaggaagg
    10441 cagctggaaa gactgaaaaa agctctggtt ttttaactgg aactgtgata gaataatgac
    10501 tacacataag aaataccagg agggcaaaca tatgccagta gtaaatgaat taatccgtat
    10561 tgaggatgac ggcacaatca gttttggcaa ttataagctg acagaaaagt cgaagcttga
    10621 taatttcgag tacaaaggtg atctctacaa ggtaaaaact catgacgaga ttacgaagct
    10681 cgaaagaaac ggactgttcg tatatgagtc agttccggga acggctgtca gccacttcgc
    10741 tgtggacgac acaactgtga agttcagtgt ggagggagcc aaggatgccc aggtaacgct
    10801 tcagctggag gacgactgcg agtatgaggt atttgtggac ggagcggcag ttggcggtat
    10861 gaagacgaat ttaagcggca agctggtagt cagcgtggag ctgaaccagg gcgaggcagc
    10921 tcagattaag gttacaaagc gttaatgcct gtaaagcggc agtgaataaa gaagcaataa
    10981 gaagaaatgc tggcagaggt cccttccggg gcctctgcct gttttcaaag attttcaaaa
    11041 agagtgcagg cagaaggaga acaaggtggc aaaagcgaaa acaactatat ttttctgcag
    11101 cgaatgcgga tacgaatcag cgaagtggac ggggcagtgc ccggcctgcc gcgcctggaa
    11161 tactatggtg gaagggctgg cagaaccggt ttccaaggct aaggctccca gaggcggtct
    11221 cacctgcgca gagccggccg gaggtctggc cggcagaaac agggcttttc aggaggtcac
    11281 gccgaaaagc ctgtcagaga ttgagctgga aaacgaggat cgggcggaca cagggtttgg
    11341 ggaactgaat cgtgtgctgg gaggcggagc agtaaaaggt tccctcgtcc tggtgggagg
    11401 agaccccgga atcgggaaat ccacgattct tctgcaggtc tgcagaaatc tggcagagag
    11461 ggggcagaag gttctctaca tttccggaga ggagtcctta aagcagatta aactgcgggc
    11521 cagccggatt ggccagatga aggagagcct ttgcttcctg tgcgagacaa acctggaggt
    11581 gatccaggcg gtagtgaagc ggacgtctcc cgatacagtg gtcatcgact ccatccagac
    11641 catgtttatg gaggatgttt cctctgctcc gggaagcgta agccaggtga gagagtgtac
    11701 gaacgcgctt cttcagattg ccaaggggct tggaatcaca atctttattg taggccatgt
    11761 gacaaaagag ggagttgtgg caggccccag agtcctggag catatggtag atacggtgct
    11821 gtatttcgag ggagaccgcc acgcctccta ccggattctc cggggagtga agaaccgttt
    11881 cggctctacc aacgagatcg gcgtctttga aatgcgggag gagggactgg cagaggtcaa
    11941 aaatccctct gaatttatgc tggaagggcg ccctgccggc gcttcgggcg ctgtggcggc
    12001 ctgctccatt gaaggcacca ggcccatgat ggtagaggta caggcccttg tgaccaggac
    12061 aaattttgga atgcccagaa gaacggcggc cggagctgat tacaacaggg tgaatctgct
    12121 gatggctgtg ctggaaaaaa gatgtcatta tgatctggga cagatggacg cctatgtaaa
    12181 catagcgggc ggcatgaaaa tgaacgagcc tgccatggat ctggctatcg tcatggccct
    12241 gatctccagc tataaggaca ggcccctgga tgagaagaca gctgtgttcg gagaggtggg
    12301 actgtcgggt gaggtccgct ccgtatctat ggcagagcag cgggtgaacg aggcggtaaa
    12361 gctgggcttt gaggcctgca ttctgcctca gatctgtctg aataagatga aaaagagaac
    12421 ggatatccgt ttaatcggcg tcagcagcgt caaggaggca gtggcagccc tgtaatggga
    12481 ctgcctgctt ccagtgaaga gggccagacc gggccaggcc ttctgggaaa aatgtatgaa
    12541 ttacatatac aatacaaaaa aagtaaaaaa agtgaaaaaa acgtttgaca agaaaatagg
    12601 tctgtgctat tatatagaag tcgacagcga gagccgctga aaacgataca aactgataaa
    12661 ggggaatagt tcaatggcag agcaacggtc tccaaaaccg ttaatggggg ttcgaatccc
    12721 tcttcccctg cttcttaata agatttagat gatggctgtg ttccttgaga agaagaggat
    12781 tgcagctgtt ttttgttttt cgtgaatctt cctgaaaggg gcagcagagg caggctaagc
    12841 tgctgaatgt ctcaaagaag ataccaaagc agatatcaaa gcagatgtca aaaactgccg
    12901 gatgctctgg aagccgtatt tcataaaacg ctatgaaaaa acaccaaaga ttaataaaat
    12961 taaagcatag atttatggac aatatctaaa aatcaacaga cgttcctgag ttctggagga
    13021 aaaagaagaa atgtatctaa aaaaatacat gaaataaaaa tccatatatt gaaaaataga
    13081 caagaacaaa gcatttttcc ttttttgagc aaaatttgac aagattcatg gctgtgtggt
    13141 ataaatgggt gaaatggagt aatactataa attgcaccaa tcaaaaggag ttaataatta
    13201 tgaagcagaa gcggatta
//
LOCUS       DBMDUW010000065        13179 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_2484_length_13179_cov_4.554596, whole genome shotgun sequence.
ACCESSION   DBMDUW010000065 DBMDUW010000000
VERSION     DBMDUW010000065.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 13179)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 13179)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13179
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2484_length_13179_cov_4.554596"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..2392)
                     /locus_tag="ACZPCR_10470"
     CDS             complement(<1..2392)
                     /locus_tag="ACZPCR_10470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vWA domain-containing protein"
                     /protein_id="HIR1231324.1"
                     /translation="MANMNSAVYAAEIATSSDALMAATPSDAAATDSNAAEILMPEQT
                     VSGEELKEEAIRAISAGHEFDFDSEIRVMKDAEGKNESYSELFKGYRSFTLFADNGNG
                     GRLTGGNDNAYGYIVVRVDKDSYEAFEKEEGTARATGSDAADSSAAERVWSLTGDEEL
                     IFLYVNADNGTVTFSLNIENLEADDIVVPSRTELYEDTEEEAEETSPAEKPAEDANEA
                     GGSGSGGGSGSGSGSSGDVQDDPTDEGASDDSQAEDGQTDDSQNENDSENDTDAEKPE
                     EKPEDGQNQEGGSDSGQENNDSSNTDKEDGNTDSGNDGNSGSGSENAGDSGNADSNGG
                     NSGSGSRSDSGKDEGGSSNQGSSSDKGGSDSDSAKLSKSSLSLPTVMGPNPNAEFEED
                     EFGDMSFDEWQEMMEEEEEEAEEDEEDYTEEVSVAYDSEDEGISYLNMTMLPAVGAVV
                     KKTEQAKGFAKLFKSSRSGEAEAVVMAGVVRIGDLVEGMAGATKSIKHLGGDKYRLHL
                     DIAGKGQALDIVLVIDNSNSMYDSKMKNLKEILTGSNGGWGSQATEGFVDQVFAKNPE
                     SRIAVVSYANTAKINCQWSSDKNRIENSIQNISERDAGGTNYEDGLLAARDVLKTKDP
                     THLPYVVFLSDGDPTYADWPENTFGDKGNYSGSGNSAGSHMEKWFQTSKNTVGEETIF
                     AAKAFREDPAAAGTTIYSVGIGRGYEEKYLKAIAGNNDEFVFSGDDLKNTFDRIFESL
                     KLEDVKIEDTLSKYVELPEGSLDKANVRVYKTDSSGRETDLSDSEYNLVYDSSTKKL"
     gene            complement(2808..4073)
                     /locus_tag="ACZPCR_10475"
     CDS             complement(2808..4073)
                     /locus_tag="ACZPCR_10475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003509429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="HIR1231325.1"
                     /translation="MIKKAEEKRGDFAVQSRKNILSVYMLGRFSVEYGGQILSLGRNS
                     SSKLIQLLQIVWLAGEKGVTKDDLAGMLYDRDSLSSLSNSLNNLVYRLRKILAENGFP
                     KSLYVINQDGVYFWDRKIPVWVDAREFERLVELGDRKRQREKETFQYYKKAEELYQGE
                     LLSAISTENWVIVESLRFKRMYEKAVSWLGDYMKRQKDYPGMYQLYHQAAQVYPFDNW
                     QVGQMESMAYMGRYKEAFLLYDNTAKRYSEEMGLPPSEKMLECYKTMSRQFVSRPDVL
                     KNIRAELREQEDEKINAYYCSLPSFIDIYRLAARRSERNGQPFCLMLCTITDYEGKVI
                     QNQEKLKARSELLRKTIGRALRRSDVYAKYSASQYLVLLMGVGEENCMVVGKRISRNF
                     RELSGKQAEVAISTDVTYVGGSMGSILDF"
     gene            4261..6090
                     /locus_tag="ACZPCR_10480"
     CDS             4261..6090
                     /locus_tag="ACZPCR_10480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009297775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PrpR N-terminal domain-containing protein"
                     /protein_id="HIR1231326.1"
                     /translation="MSDKKVRILGIAPYEGMRSIMLKAAEARNDIDLTVYVGDLQEGA
                     EIAKRSFHDNYDIIISRGGTAELIGQITPIPVVEIPLSVYDILRAIKMAENFASRYAI
                     VGFPGIISSAKLLCDLLQYKVETFTIHNSRQVEETLQMLKKRGYRMILCDMIASTTAK
                     RLGLNAILITSGNESISSAFDQAVKLCSSYANVREENRFLREVIRTSSQSTVIFDSQG
                     QIFYSSLPENEENPVIQALKKDLPSASETPHKSFKNIDGTLYSITSRLVSFCGDNYPV
                     FQFTDSKVPFATSKYGVQYLNRIDVENSFFNSFFSVTGAIGPLRNTIVQMAQTQHPIM
                     IFGEEGTGKEQAAAAVYNESPLRNNPFITVNFALMNDKSWNFLTNHYNSPFNDNNNTI
                     YLKNLHVLDEERARKLLSIIVDMNLCHRNRLIFSCVCSRSGEIPKTCMEFVNLLTCLT
                     IRLKPLRERTEDIPTLANLYLSNLNVSLAKEILGLTPGAMELLKSFDWPENYTQFKRI
                     LSELTVITTSSYITEETLSGLLEMEKKTTFRRVGPGASPSEIEGESGVSHSSSVILDL
                     KRPLDEINQDIIHAVLEETKGNQTAAAKRLGISRTTLWRLLKS"
     gene            6187..6789
                     /gene="thrH"
                     /locus_tag="ACZPCR_10485"
     CDS             6187..6789
                     /gene="thrH"
                     /locus_tag="ACZPCR_10485"
                     /EC_number="3.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016282603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoserine
                     phosphatase/homoserine phosphotransferase ThrH"
                     /protein_id="HIR1231327.1"
                     /translation="MYIVCLDMEGVLVPEIWIAFAEASGIPELKRTTRDEPDYNKLMR
                     WRLDVLKEHGLGLPEIQKTIAQIDPLPGAKEFLDELRSFTQVIVLSDTFEEFAMPLMK
                     KLGYPALFCNSLSVDPDGTITDFHMRVENSKLTTVKALQSIGFETIASGDSYNDLGMI
                     QASKAGFLFKSPESIRASVPEIPAFDTFDELLNAIKQAMV"
     gene            complement(7167..8039)
                     /locus_tag="ACZPCR_10490"
     CDS             complement(7167..8039)
                     /locus_tag="ACZPCR_10490"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008390743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HIR1231328.1"
                     /translation="MKKLGRNDACWCGSQKKYKHCHEAFDEKLEEAARAGHFIPSHDM
                     IKTPEQLEGIRESCKINIAVLDYVAEHIHAGVTTEEIDKWVYDETTKRGGIPAPLGYQ
                     GFPKSVCTSIDDQVCHGIPSEDVVLKDGDIINVDVSTIYKGYYSDSSRMFCIGEVSPE
                     KKKLVDVVKECVELGLEQVKPWGFLGDMAHAVNEHAVKNGCSVVREIGGHGVGLEFHE
                     EPWVGYIGEPGTGMMMAPGMVFTIEPMVNMGGCEVYVDDSDGWGVYTEDGRPSAQWEI
                     MVLVTETGHEVLCW"
     gene            8284..9396
                     /locus_tag="ACZPCR_10495"
     CDS             8284..9396
                     /locus_tag="ACZPCR_10495"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1231329.1"
                     /translation="MNKHEDRLRHFPAPKTRAANMAVTLAFLFTATAVSFFFFTKMKE
                     PSSSISLCYILALFLTARYTTGYFYGVLSALISVGCVNFLFTYPYFELNFTLTGYPMS
                     FIAMFTISIITSALTTNIKEQARIISEREKLLMDAEKEKMRANLLRAISHDLRTPLTS
                     IIGSSTVYLENEAHLTDIEKKSLVSHILEDSNWLLNMVENLLSVTRINNETARVNTSM
                     EPVEEVMGEAVSRLKKRIPDAPIHVRVPDEILIIPMDAILIEQVLINLMENAVVHSKS
                     TKPIECFADSSPDFVTFHVRDYGVGIPAEKLNTIFDGSSSTASSSTDGRKGMGIGLSI
                     CKTIINAHGGTLAAFNHPDGAEFYFKLPKEDSSIVS"
     gene            9386..10096
                     /locus_tag="ACZPCR_10500"
     CDS             9386..10096
                     /locus_tag="ACZPCR_10500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HIR1231330.1"
                     /translation="MSHKISILLVEDEPNICNFITATLSAHDYRVSQAHTGKDALSII
                     TSQCPDLILLDLGLPDMDGMEIIRQVRTWASIPIIVISARIQEQEKVKALDLGADDYL
                     TKPIGTSELLARIRTAMRHSNRLNTDSLLYKRPFQAKDLVIDFDKHLVTVGGQETHLT
                     QNEFKIIALLAKNSGRVMTYDSIIENIWGPYADGDNSILRVNMAHIRRKIEKNPAEPE
                     YIFTEIGIGYRMIEDEMN"
     gene            complement(10189..10989)
                     /locus_tag="ACZPCR_10505"
     CDS             complement(10189..10989)
                     /locus_tag="ACZPCR_10505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HIR1231331.1"
                     /translation="MLLVRHINMFFQFYDIEKDKGTIVMLDGKTVTPLYVQLMNQIEE
                     KIRCGVYQPGERLQSESEMAKTFGVSIITVRSAVSGLVEKGLVEKKQGKGTFVSKPKF
                     TKDMKNLQSFTEMCRYMGMEPGGKMLENCLASPDDKTRKLLGLEKDIQVISISRLRYA
                     DGQPVAIEKNYFPTKYAFLLDETFDNNSLFSFLHEKAKVTVSASEKWIGLCRATASEA
                     KLLEVKKGSSLLFIKSVTYTQDNEPLYVGVQIFNGENCSLYIYQSNGI"
     gene            complement(11027..11458)
                     /locus_tag="ACZPCR_10510"
     CDS             complement(11027..11458)
                     /locus_tag="ACZPCR_10510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="secondary thiamine-phosphate synthase enzyme
                     YjbQ"
                     /protein_id="HIR1231332.1"
                     /translation="MLIKSFTHEIASREEFHMVKITEQVKKDVEESGVKNGVVFVISL
                     HTTTGIMINESLPCVEKDIELTLERLIPADGPYVHTHMLPSYGTCSGNAPGHLKSMLC
                     GNHCVLPVSDGKMAGGSAQDIYFVEFDGLKIRHYTVQIMGE"
     gene            complement(11448..12314)
                     /locus_tag="ACZPCR_10515"
     CDS             complement(11448..12314)
                     /locus_tag="ACZPCR_10515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HIR1231333.1"
                     /translation="MVIDMHVHPVLFGPICEDKKKVEFRKQKFGLYKSSPIPMSQVMA
                     VMDHAGVDKAVLLAEDYSAEMGQPIITNEEVKQLVDLEPDRFIGFASVDPRDCGAKEQ
                     LERAFSELKLSGLKLNLSHLQMYPDDKRLEPLLKLCMQYEKPVMFHSGFSWEPDSPSK
                     YGRPILYEDIAMEYPSLRFCLAHLGWPWVDELCMMLLKYPNVYTDTATVFMDSPANYY
                     DQIFMKNMAPGWLQNNLMDKVMFGSNLPRFRQVRTREGLEKLPIRKDVLDKILGGNAK
                     VFLGMEVRDYAY"
     gene            complement(12320..13129)
                     /locus_tag="ACZPCR_10520"
     CDS             complement(12320..13129)
                     /locus_tag="ACZPCR_10520"
                     /inference="COORDINATES: protein motif:HMM:NF012515.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="HIR1231334.1"
                     /translation="MKFAVVGFTCIDVYKNLGIQYPTGNGIDLLFNLMEQVEEIEPSV
                     VTAVGDDKNGKQLLEECRIRQVDTSHVQVVPGGKTAVIEMLLNGKDRVHHSVDRGVMP
                     DYRPTKEDMDFICSQDYIHTDLSWNVVDLLPEIKKSGTKIYFDFSKRYQHPDVPKILS
                     SIHYGIFSFEEETEEVRELLKMGCERGAEVLLATFGEKGSLAYDGRNFYRQKCLASEN
                     LVNTVGAGDSYGSGFMAGIIRGEDIQACMERGARKAAEIVSIFEPYHRKGR"
BASE COUNT         3112 a         3677 c         2735 g         3655 t
ORIGIN      
        1 tcagtttctt tgttgaagaa tcataaacca ggttatattc actatcgctt aaatctgtct
       61 ccctgcctga gctgtctgtt ttgtataccc gtacatttgc cttatccagg cttccctctg
      121 gaagctctac atatttgctc agcgtatctt caatctttac atcctcaagc tttaagctct
      181 caaaaattct gtcaaatgtg tttttaagat catctcctga aaaaacaaac tcgtcattat
      241 ttccagcgat ggctttcaaa tatttttctt cgtatcccct gccgattcct accgaataaa
      301 tggtagttcc tgctgcagcc ggatcctctc taaaagcttt agcagcaaat atagtttctt
      361 ctccaacagt atttttacta gtttgaaacc atttttccat atgagatcca gcgctgtttc
      421 cgcttccaga atagttacct ttatctccaa atgtattttc tggccagtct gcataggtcg
      481 gatctccatc gcttaaaaat acaacatatg gaagatgggt tggatccttc gtttttaaaa
      541 cgtctctggc tgctaataaa ccgtcctcgt agttagtacc gcccgcatcc cgttcagata
      601 tgttttgaat actattctct atgcgatttt tgtcactact ccactgacaa tttattttag
      661 ctgtgtttgc atagctcaca acagcaattc tgctttccgg gttcttggca aaaacctggt
      721 caacgaagcc ttctgttgct tgagaacccc agccgccatt acttcctgtc aggatctcct
      781 tcaggttttt catcttagag tcatacatgc tgttggagtt atcaattacc agcacaatgt
      841 caagagcctg accttttccg gcaatatcaa gatgaagtct gtacttatcc cctccaaggt
      901 gcttgatgct ttttgtcgct cccgccatgc cttcaaccag atcgccaatt cttacaactc
      961 ccgccatcac aacagcttcc gcctcaccgc ttctgctgct cttaaacaat tttgcaaatc
     1021 cctttgcctg ctctgtcttc ttaacgactg cgccgactgc cggaagcata gtcatattga
     1081 ggtaggagat tccctcgtcc tcgctgtcgt aagcgacgga cacttcctct gtgtagtctt
     1141 cctcgtcttc ttctgcctct tcctcttctt cctccatcat ttcctgccat tcgtcgaagc
     1201 tcatgtcgcc gaactcgtcc tcctcgaact ctgcgttcgg gttaggaccc attacggtag
     1261 gaagactgag gctggatttg gaaagcttcg cgctgtcgga atcggatccg cccttgtcgg
     1321 agctgcttcc ctgattggag gagccgccct catccttacc gctgtcagat ctgcttccag
     1381 aaccggagtt tccaccgttg gaatcggcat ttccgctgtc tcctgcgttt tcggatccgc
     1441 ttccgctgtt tccgtcattt ccggaatctg tatttccgtc ctctttatct gtatttgagg
     1501 agtcgttatt ctcctgtccg ctgtcagagc cgccttcctg attctggccg tcctccggct
     1561 tctcctctgg cttctctgca tctgtatcgt tttcgctgtc gttctcgttc tggctgtcgt
     1621 ctgtctgtcc gtcttctgcc tggctgtcgt cagaggctcc ctcgtcggtc ggatcgtcct
     1681 gaacgtcgcc gctgcttccg gaaccgcttc ctgagccgcc gccggaaccg gatcctcctg
     1741 cctcgttggc gtcctcagcc ggtttctctg ccgggcttgt ctcctcagcc tcttcctctg
     1801 tgtcttcgta aagctctgta cggcttggaa cgacaatgtc gtctgcctcc agattttcaa
     1861 tgtttaaaga gaaggttact gttccgttgt ctgcattgac ataaaggaaa attaactcct
     1921 cgtctcctgt caggctccat acccgctctg cggcgctgct gtcagccgcg tcggaaccag
     1981 tcgctctggc tgttccctct tccttctcaa acgcctcgta ggaatcctta tctacgcgga
     2041 ctacgatgta accataagcg ttgtcattgc cgcctgtcag acgtcctccg tttccattgt
     2101 cagcaaaaag cgtgaagctt ctgtagccct tgaacagctc gctgtagctc tcgtttttgc
     2161 cctcagcgtc cttcattacg cggatttctg aatcaaaatc aaattcatgg cccgccgaga
     2221 tagcccggat tgcctcttcc tttaactcct cgccgctgac agtctgttcc ggcataagaa
     2281 tctctgccgc attgctgtct gtcgccgccg catcgcttgg agtcgctgcc atcagcgcgt
     2341 cactggatgt ggcaatttct gctgcataca cggctgaatt catatttgcc atgcacatac
     2401 agaaaacaag gagccatgca actgcgcgtc ttacggttct cttcatgggg ctgttgcttt
     2461 tagcgcgcga cattttcttt ctggactcca tacttacccc cgcttttcct tccatcactc
     2521 caactcaacc tcctcttttt ctatcgcaaa ttcgtctctt ttacggattt ctttttgtct
     2581 tttttttgtc agatttctta actttttctg aattcccctt cattttattc gattgccaat
     2641 cataaaacca atcacaaaaa gtcccatttt tattttttct gttttttagc accagagcca
     2701 ggtcttccgg cagactctca agcctgccgg ctggcttttt cctatgaaat aaaaaaatgc
     2761 ctaccctgtc tgccgacagg ataggctgcg cctcctctta tgcacattta aaaatccaaa
     2821 attgagccca tactcccccc cacgtatgta acgtcggtcg aaatggctac ctccgcctgt
     2881 tttcccgaga gttcccggaa attccggctg attctcttcc ccaccaccat acaattctct
     2941 tcccccactc ccataagcag aaccaggtac tgggacgcgc tgtacttggc gtaaacgtcg
     3001 ctccgcctga gcgcccggcc aatagtcttt ctcaaaagct ccgagcgggc cttcagcttc
     3061 tcctggttct ggataacctt tccctcatag tctgtgattg tacacagcat cagacagaag
     3121 ggctgtccgt ttctctcgct gcgccgcgct gccagacggt aaatgtcaat aaagctgggc
     3181 agagaacagt agtaggcgtt aatcttctcg tcctcctgct cccttaactc cgccctgatg
     3241 ttcttcagca cgtccggacg gctgacaaac tggcggctca tggttttata gcactccagc
     3301 attttttcgg agggaggaag ccccatctcc tccgaatacc gcttggccgt attgtcatag
     3361 agaagaaacg cctccttgta tcttcccatg taggccatgc tctccatctg ccccacctgc
     3421 cagttgtcga aggggtacac ctgggccgcc tggtggtaca gctggtacat gccggggtaa
     3481 tccttctgcc gcttcatata gtcgcccagc catgaaaccg ccttctcata catccgctta
     3541 aagcgcaggc tctccacgat gacccagttt tccgtggaaa ttgcgctcag gagctcgccc
     3601 tggtaaagct cctccgcctt cttataatat tgaaaggtct ccttctcccg ctgccgtttt
     3661 ctgtctccca gttccaccag acgttcaaat tctctggcgt ccacccagac tggaattttt
     3721 ctgtcccaga aataaacacc gtcctgatta atcacataga gggattttgg aaagccgttc
     3781 tccgccagaa ttttccgcag gcggtaaacc aggttattga ggctgttgct cagactggaa
     3841 agcgaatcgc ggtcgtaaag cattcccgcc agatcgtcct tggtcacgcc cttttccccg
     3901 gccagccaca caatctgaag cagctgaatc agcttcgagg agctgtttct tccaagcgac
     3961 aggatctgcc ctccatactc cacagaaaac cggcccagca tatagacaga taagatattc
     4021 tttctgctct gcaccgcaaa atcccccctt ttttcctctg cttttttaat catatcgtaa
     4081 aaattcgtcc tcgtccagtc acattcttag atgtttcagt aaatttatgt aaacttattt
     4141 tttctgtttt ttcattttaa aacgtctttc cttccttttt taaacgtgtt ataatgaact
     4201 tgtttcacat tgaaacaaat ataacaaacg ctgacagcgc caatcgggga ggaatgagac
     4261 atgagcgata aaaaagtacg gattctgggg atcgcaccct acgaggggat gcgttcgatt
     4321 atgctgaagg cggccgaggc ccggaacgac attgatctga ccgtctatgt gggcgacctg
     4381 caggagggag cagaaattgc caagagaagc tttcacgaca attacgatat tatcatttcc
     4441 cgcggcggta ctgcggagct gatcggacaa atcactccca ttcctgtggt ggagattccc
     4501 ctgtctgtct acgatattct ccgtgccatc aaaatggcgg aaaattttgc ctcccgctat
     4561 gccatcgtag gctttccagg cattatcagc agcgccaaac tgctctgcga tctgctccag
     4621 tataaggtgg agacctttac gatccacaat tccagacagg tggaggaaac gcttcagatg
     4681 ctgaaaaaga ggggctaccg catgatcctg tgcgatatga ttgccagcac cactgcgaag
     4741 cgcctgggcc tgaacgcgat tctgatcacg tccggcaatg agagtatcag cagcgccttc
     4801 gatcaggcgg tgaagctgtg ctccagctac gccaatgtgc gggaagaaaa ccggtttctc
     4861 cgcgaggtca tccgcaccag cagccagtcc accgttatct ttgacagcca ggggcagatt
     4921 ttttactcct ctctccctga aaacgaagaa aatcctgtga ttcaggcgct gaaaaaggat
     4981 ctgccctccg cctccgaaac gcctcataaa agctttaaaa acattgacgg aactctgtat
     5041 tctattacca gccgccttgt ttccttctgc ggggacaatt atcctgtgtt ccagtttacg
     5101 gacagcaagg ttcccttcgc caccagcaaa tacggggttc agtacctgaa ccgcatcgac
     5161 gtggaaaaca gctttttcaa cagctttttc agcgtcacag gggccatcgg gccgctgaga
     5221 aacaccattg tccagatggc ccagacccag catcccatta tgattttcgg ggaggagggc
     5281 acgggaaaag aacaggctgc cgccgcagtc tacaatgaaa gtcctctgcg gaacaacccc
     5341 tttatcaccg tcaattttgc cctgatgaat gataaaagct ggaattttct caccaaccac
     5401 tacaattcgc cgtttaatga taataacaac acaatctacc tgaaaaacct ccacgttctg
     5461 gacgaggaac gggccagaaa actcctgtcc attatcgtgg acatgaatct gtgccatcga
     5521 aaccgcctga ttttctcctg cgtgtgcagc cgcagcggag aaattcccaa gacctgcatg
     5581 gaatttgtga atcttctcac ctgcctgacc atccgcttaa agccgctccg ggaacggacg
     5641 gaggacattc ccaccctggc caacctctat ctgagcaatc tgaacgtctc tctggccaag
     5701 gaaatcctgg ggctgacgcc cggcgctatg gagcttttaa agtccttcga ctggccggaa
     5761 aattatacgc agtttaaacg gattttaagc gagctgaccg tgatcaccac ctcctcctac
     5821 atcacggagg aaaccttgtc cggcctgctg gaaatggaga aaaaaactac cttccggcgc
     5881 gtaggccccg gcgcttctcc ctccgaaatt gaaggagaaa gcggcgtttc ccacagttcc
     5941 tctgtgattc tcgatctgaa acgcccgctg gatgaaatca accaggatat tatccacgcg
     6001 gttctggagg agaccaaggg aaatcagacg gctgcggcga aacgtctggg catcagccgg
     6061 acgacgctgt ggcggcttct gaaatcgtag cgcagcattt gtctgccggc ccgccctgcc
     6121 cttttcttga caccttgcag gctgggtgat agtatgaaaa aaataattta gaggaggatc
     6181 ataagtatgt atattgtatg ccttgatatg gagggagttc tggttcctga gatatggatc
     6241 gcctttgccg aggccagcgg catcccggag ctgaaacgca ccaccagaga cgagccagat
     6301 tacaataagc tgatgcgctg gagacttgac gtattaaaag aacacggact ggggctgccc
     6361 gaaatccaga aaaccattgc ccagattgat ccgctgcccg gcgcgaagga attcttagac
     6421 gagctgcgct ccttcaccca ggtcatcgtg ctcagcgaca cgttcgagga gttcgccatg
     6481 cccctgatga aaaagctggg atacccggcc ctgttctgca actcgctcag cgtcgatccg
     6541 gacggaacga tcacggattt ccatatgcgg gtggaaaact ccaagctgac cacagtgaag
     6601 gccctgcagt ccatcggctt tgagaccatt gccagcggag acagctacaa cgatctgggc
     6661 atgatccagg ccagcaaggc cggttttcta ttcaaaagcc ctgaaagtat ccgcgcctct
     6721 gtaccggaaa taccggcctt cgacaccttt gacgaactgt taaacgccat caaacaggcc
     6781 atggtatagg tttcgttata atttctttat gattccgtaa gattggttta gaagtttttt
     6841 agagactgga caaatattag acacatttat cggttattat aatcatgtaa acaacaagag
     6901 gccaatgagt acagaaacag cgcgcatcgt ttcattggac tcgcctaaca actatttcct
     6961 ttatatagat tttctggaac ccctttttcc tttccccctt ttatgtttca gaaaaaaacg
     7021 ggagcactgc agacagcggc gtaagcgccg ggcagtgctc ctctttttta tatcgtttta
     7081 tgccgccttt cagtatctct gtgcaggaag ctgcgcggtt ctctgtccgc tgacgccaga
     7141 accggcatcg gatctgccgc gtttttctac cagcacagta cctcgtggcc tgtctctgtc
     7201 accagcacca tgatctccca ctgggcggac ggtctgccgt cctctgtata cacgccccag
     7261 ccgtcgctgt cgtccacata gacctcgcag ccgcccatat tgaccatagg ctcaatggta
     7321 aataccatac caggggccat catcatgccc gttccaggct ctcctatgta tccaacccac
     7381 ggttcctcat ggaattccag tcccacgccg tggccgccga tctcccgcac tacgctgcag
     7441 ccgttcttta ccgcgtgttc attgaccgca tgggccatat ctcccagaaa gccccagggc
     7501 tttacctgct caaggcccag ctccacgcac tccttcacta cgtccaccag ctttttcttc
     7561 tccgggctca cctccccgat acagaacatg cgggaagaat cagagtaata tcccttgtaa
     7621 attgtggaaa cgtccacatt gataatatct ccgtccttta ataccacatc ctctgaagga
     7681 atcccgtggc acacctgatc gtcaatggag gtgcagacgc ttttgggaaa gccctggtat
     7741 cccagaggag ccgggattcc gcctctcttt gtggtctcat cgtaaaccca cttgtcaatc
     7801 tcctctgtag tcactcccgc atgaatatgc tccgctacat agtccagaac cgctatgtta
     7861 atcttgcagc tctccctgat tccctctaac tgctccggcg tcttgatcat atcgtgagac
     7921 ggaataaaat ggcccgctct ggccgcctcc tccagctttt cgtcaaaggc ctcgtggcag
     7981 tgcttgtatt tcttctggct gccgcaccag caggcgtcgt ttcttccaag tttcttcatg
     8041 gttcagcgct tcccttcttt tctttattct tcagcgtcag cgtacacgga cgcttttatt
     8101 aattttataa aataatccaa cacttgaagt ctatcacagg aaaagataaa aagcaaattc
     8161 aggggaagga ggcgaaagaa attttccttc tctccctctc ttaacatctt ttttactgaa
     8221 ttttcccgcg aagtcaggta taataaatag attatcaata tttatgacag gagcgtgcgc
     8281 gttatgaaca aacacgaaga caggctgcgg cattttccgg cccctaaaac cagggcggcc
     8341 aatatggcgg ttactctggc gtttctcttt accgctaccg ctgtctcgtt tttctttttt
     8401 acaaaaatga aggaaccttc ttccagtatc agtctgtgct acattcttgc tctctttttg
     8461 acggcccggt acaccaccgg ctatttttac ggggtgctgt cggcgctgat cagcgtggga
     8521 tgcgtgaatt ttctcttcac ctacccctac ttcgagctga atttcacact gaccggctac
     8581 cccatgagct ttatcgccat gtttaccatt tccattatta ccagcgccct gacgacaaat
     8641 atcaaggagc aggcccggat tatctcagag cgggaaaaac tgctgatgga cgcggaaaag
     8701 gaaaagatga gagctaacct gctgcgggcc atttcccacg atctcagaac ccctctcacc
     8761 agcattatcg gctccagcac cgtctatctg gaaaatgaag cccacctgac ggatatagag
     8821 aaaaaatctc tggtgagcca tattttagag gattccaact ggctgctgaa catggtggaa
     8881 aatctcctct ctgtcacacg cattaacaat gaaaccgcca gagtcaatac ctccatggaa
     8941 ccggtggagg aggtaatggg agaggctgtc agccgtttga aaaagcggat tccggacgcg
     9001 cccatccatg tccgggtacc agatgaaatt ttaattattc ccatggacgc catcttaatc
     9061 gagcaggtgc tcattaacct gatggaaaac gcggtggtgc attccaagag cacaaagccg
     9121 attgaatgct ttgccgattc gtcgcctgat ttcgtcacct tccacgtgcg ggattacgga
     9181 gtcggcattc ctgcggagaa gctgaatacc atctttgacg gctcctcctc cactgccagc
     9241 tcctccaccg acggacgaaa aggcatggga atcggtcttt ctatctgtaa aaccattata
     9301 aacgcccacg gcggcaccct ggctgccttc aaccaccccg acggggcgga attttatttt
     9361 aagcttccaa aggaggactc aagcattgtc tcataaaata tctattcttc tggtagaaga
     9421 tgaaccaaat atctgcaact ttatcacggc cacactctct gcccatgact acagagtttc
     9481 ccaggcccat acgggaaagg acgccctgtc catcattacc tcccagtgcc cggatctgat
     9541 tctcttagat ttgggacttc ccgatatgga cggcatggaa atcatccgcc aggtgagaac
     9601 ctgggccagc atcccgatta tcgtcatttc cgcccgcatt caggagcagg aaaaggtgaa
     9661 agctctggat ctgggcgcag acgactacct gacaaagcct atcggcacgt cggagcttct
     9721 ggcccgcatc cgcaccgcca tgcgccacag caaccggctg aatacagatt cacttctgta
     9781 caaacggccg ttccaggcca aggatctggt catagatttc gacaagcatc tggttactgt
     9841 gggcggtcag gaaactcatc tgactcagaa cgaatttaaa attatcgctc tgctggccaa
     9901 aaattccggc cgcgtcatga cctacgactc cattatcgag aatatctggg ggccctacgc
     9961 agacggagac aacagcattc tccgcgtcaa tatggcccat atccggcgca agatcgaaaa
    10021 aaatccggca gagccggagt acatttttac ggaaatcggg attggatatc gtatgataga
    10081 ggatgagatg aattagaaat gtaataagga gagagggagc aagttttctg cgctccgcca
    10141 aaagcttagt cgctggaaaa cttctccctc tctccttttg tctctttttt atattccgtt
    10201 ggactgataa atatataatg agcagttttc accgttaaat atctgaactc ccacatacag
    10261 aggctcatta tcctgggtgt atgtgacact cttgataaac agcagggagg aacctttttt
    10321 tacctccagc agctttgcct cagatgcagt agctctgcaa agtccaatcc atttttctga
    10381 cgctgaaacg gttacttttg ctttttcatg aagaaatgaa aataatgaat tattatcaaa
    10441 ggtttcatct aataaaaatg catattttgt tggaaaatag ttcttttcaa ttgccacagg
    10501 ctgtccatct gcatatctta gacgagaaat ggaaatcacc tggatgtctt tctccaatcc
    10561 taataatttt ctggttttgt catctgggga tgcaagacaa ttttccagca tttttccgcc
    10621 tggctccatt cccatatacc ggcacatttc tgtgaagctt tgaagatttt tcatatcctt
    10681 ggtgaatttt ggttttgaaa caaaggtccc ttttccctgt ttcttctcta ccaagccttt
    10741 ttccaccaaa ccgctgacag cgcttctcac ggtaataata ctcaccccaa atgtctttgc
    10801 catctcgctt tcagactgga gtctttcacc tggctgataa acgccgcagc gtattttttc
    10861 ttctatttga ttcattaact gcacatataa gggggtcact gtctttccat ccagcataac
    10921 tattgttcct ttatcctttt caatatcata aaattggaaa aacatattaa tatgtctcac
    10981 caataacatt atatctcaat cttttataaa aggcaaagaa ttttccctat tctcccatga
    11041 tttgaactgt ataatgtctg attttaagac cgtcaaactc gacaaaataa atatcctgtg
    11101 cgctgcctcc tgccattttc ccgtcagaaa ccggaagaac acagtgattt ccgcacagca
    11161 tggattttaa atgtcccgga gcgttgccgc tgcaggttcc atagctgggc agcatatgcg
    11221 tatgaacata agggccgtcg gcaggtatca gccgttctaa ggtaagctct atatcctttt
    11281 ccacgcaggg aaggctttca ttaatcataa ttcctgtagt ggtatgaagc gaaatgacaa
    11341 aaacgactcc atttttcact ccgctttcct ctacatcctt ctttacctgc tctgtaatct
    11401 tcaccatatg gaattcttct ctgctggcaa tctcatgagt aaaggactta ataagcatag
    11461 tctctcacct ccattcccag gaagactttt gcgttgcctc ccagaatctt atctaacaca
    11521 tctttcctga tcggcagctt ctccagtccc tctctggttc tgacctgtct gaatctgggc
    11581 aggttcgatc cgaacataac cttgtccatc agattattct ggagccatcc cggcgccata
    11641 ttcttcataa aaatctgatc gtaataatta gctggactat ccataaatac agtagctgta
    11701 tctgtataca cgtttggata tttgagcagc atcatacaca gctcatctac ccacggccat
    11761 cccagatggg ccaggcagaa cctgagggaa gggtactcca tcgcgatatc ctcatacaga
    11821 atcggccgtc cgtacttgga cggagaatcc ggctcccagc tgaatccgct gtggaacatc
    11881 acaggctttt catactgcat gcacagcttt aacagcggtt ccagcctttt atcgtcagga
    11941 tacatctgaa gatggcttaa attcagcttc agtcctgaaa gctttaactc tgaaaatgcc
    12001 cgttccagct gctccttagc gccgcagtcc ctgggatcca cgcttgcgaa tcctataaac
    12061 cggtctggct ccaaatctac cagctgtttg acttcctcat tagtgataat cggctgtccc
    12121 atttctgccg aatagtcctc tgccaggagc accgccttgt ccactcccgc gtgatccatc
    12181 acagccatga cctggctcat aggaatggga gaagatttgt aaagaccaaa cttctgcttt
    12241 ctaaactcta ctttcttttt atcttcacaa atcggcccga acaggaccgg gtgaacatgc
    12301 atatctataa ccataattat tatcttcctt tcctatgata tggctcaaaa atgctgacaa
    12361 tctcagccgc tttcctggct ccccgttcca tacatgcctg aatatcctct cccctgatga
    12421 ttccagccat aaagccggat ccataggaat ccccagcccc taccgtgttc accaaattct
    12481 ctgaagcgag gcatttctgg cggtaaaagt tccttccatc ataggccagg gagccttttt
    12541 ctccaaaggt tgccagaaga acctctgccc ctctttcaca ccccatttta agcagttccc
    12601 ttacctcctc tgtctcctct tcgaatgaga aaataccgta atggatggaa cttaaaatct
    12661 tcggcacgtc cggatgctga taccgcttgg aaaaatcaaa atatatcttt gtcccactct
    12721 tcttaatctc aggaagcaga tcgaccacat tccaggataa gtctgtgtga atgtagtcct
    12781 ggctgcatat aaaatccata tcttcctttg taggcctgta atccggcatg actcctctgt
    12841 ccacagaatg gtgaaccctg tcttttccgt ttaacagcat ttctatcaca gccgtttttc
    12901 ccccaggaac cacctgcaca tgagaggtat ctacctgcct gattctgcac tcctctaaaa
    12961 gctgttttcc atttttatcg tcgcctacag ctgtaactac agaaggctct atttcctcca
    13021 cctgctccat cagattaaac agcaggtcaa taccgtttcc agtcggatac tgaatcccca
    13081 gatttttata gacatcaata catgtaaatc ctaccactgc aaatttcata cctcttctcc
    13141 tctttttttt aaaccccatg atttaagtca gacagccta
//
LOCUS       DBMDUW010000066        13088 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_2504_length_13088_cov_2.107877, whole genome shotgun sequence.
ACCESSION   DBMDUW010000066 DBMDUW010000000
VERSION     DBMDUW010000066.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 13088)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 13088)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13088
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2504_length_13088_cov_2.107877"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(55..672)
                     /gene="lexA"
                     /locus_tag="ACZPCR_10525"
     CDS             complement(55..672)
                     /gene="lexA"
                     /locus_tag="ACZPCR_10525"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HIR1231335.1"
                     /translation="MSQEKITPKQQEILEYIKETILKKGYPPAVREICEAVNLKSTSS
                     VHSHLETLERNGYIRRDPTKPRTIEIIDDCFNLARREVVNVPLLGTVAAGMPLLAQEN
                     IENYFPIPTEMLPDKEVFMLRVKGDSMIEAGIFNGDLIFVEKTVTAENGEIVVALLDD
                     SATVKRFYKENGHYRLQPENSSMEPIIVDEVQILGKVFGLFRMKM"
     gene            897..1304
                     /locus_tag="ACZPCR_10530"
     CDS             897..1304
                     /locus_tag="ACZPCR_10530"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HIR1231336.1"
                     /translation="MKGKSRKKGKLAERGVSLSGSVYSPDSCLIRPNCPAAKILFSAA
                     ALFALCVILTTVNLLSSQAEEQKSSPYHKYYTSIQIQDGDSLWSIAETYRTHSGKSAA
                     EYVCDLKEMNSLSEDTIHAGHYLTIYYYDSVPK"
     gene            complement(1332..2384)
                     /locus_tag="ACZPCR_10535"
     CDS             complement(1332..2384)
                     /locus_tag="ACZPCR_10535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HIR1231337.1"
                     /translation="MAVLSYHEQEMIENTKKLRKLIRELPPFCADFFRGIEPRTSSRT
                     RIAYAYDLSIFFDFLIQTNPIWKNKDKRDFTVDVLDQIGVMDLEEYLEFLKCHSTENK
                     EDLINTERGLTRKMSSLKSFYNYFFRNERIQTNPAALVKLPKLHEKEIVRLEIDEVAR
                     LLDLVEDGDSLTERQKAYHKKTRVRDLALMTLLLGTGIRVSECIGLNLNDVDFNVDGI
                     RIHRKGGKEVIIYFGDEVELALRDYMEERRHIVPAPGNEEALFLSMQKKRLNVRSVEN
                     LVKKYAQAAAPLKKITPHKLRSTYGTNLYRETGDIYLVADVLGHADVNTTKRHYAALE
                     DERRRSARNKVKLREN"
     gene            complement(2429..3166)
                     /locus_tag="ACZPCR_10540"
     CDS             complement(2429..3166)
                     /locus_tag="ACZPCR_10540"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007864824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0032267 - tRNA(Ile)-lysidine synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase"
                     /protein_id="HIR1231338.1"
                     /translation="MKLQRLLSLTRQALDAYDMIDPGDKIAVGLSGGKDSLALLYAMK
                     HLQKFYPKSFDLCAVTVDLGFGNFDLQAAKIFCQKLSVPYTVVPTEISQIVFESRQES
                     NPCALCAKMRKGALNKAAKDLGCNKIAYAHHRDDVIDTMMLSLIYEGRFHTFSPKTYL
                     DRMDLFVIRPFLYVSEADIIGFKNRYQLPVCKNPCPVDGKTKREFVKNLIKSINTEAP
                     GVKDRFFHAVASGNIPGWPVNENNNRK"
     gene            3366..3509
                     /locus_tag="ACZPCR_10545"
     CDS             3366..3509
                     /locus_tag="ACZPCR_10545"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231339.1"
                     /translation="MKKLRSAGLALLLALTSAFSALAAPAVPPARAPAVSSSNAIDFY
                     GLM"
     gene            complement(3557..5542)
                     /locus_tag="ACZPCR_10550"
     CDS             complement(3557..5542)
                     /locus_tag="ACZPCR_10550"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013073.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0000270 - peptidoglycan metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HIR1231340.1"
                     /translation="MLTVLAMAALAVPPAALSEWMKESGKGYVEALSASHSLKKEKQE
                     EGKQEKKSVETLPDEKTFFSMAQGCLKGVGEYLHGFWQSFGYAPSPEEYNLAYLFPLE
                     DTAEEEKGGEASQKTAADILLQTVLQKLSRFGPELHQKSAGGELFEELNEKEQNWMYR
                     IYQELNRLPYRTGIRFRFLNGDGTESANYSNTKEILALTNVYSYFHQWDHVQSSEAYA
                     LKLWDLSHQYDISVGSVYYCDGCEETDEEETEFTPAQSGTADETKESGQESVRIQETV
                     PQTEGETGGASASVSSQNVGNDAGVSETSGQNPAESAVAVPEKKEEPMPAESVSGSVS
                     APESTSALESVSAPESVSSASAETTQAKETVSAALKEESVSETEGQTETAQPQQKNPE
                     ASEENGAAQGNSSGSGTADLSICPGHVDVVVTITITGLNEQKNLFFLAASIQETEEEK
                     TDSANNENGGWTGWTEERQAAARRLASLDWEAKYGLKSEEMSFGKTLTKQELEAHMAL
                     LPEDISPERRKLIAFALDSVGKIPYHFGGKASRPGYSGNQFFSVTEPDQMGRTLKGLD
                     CSGWINWVYWSALGTPVARGGTSSLASSGTEIPREELKPGDIAVVPGDEAHVVMFLGW
                     DPATGKMICIHESAGRANNVTVSLSDRAWTHYRRILE"
     gene            complement(5789..6442)
                     /locus_tag="ACZPCR_10555"
     CDS             complement(5789..6442)
                     /locus_tag="ACZPCR_10555"
                     /EC_number="2.7.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013272695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0050145 - nucleoside monophosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidylate kinase-like family protein"
                     /protein_id="HIR1231341.1"
                     /translation="MKHNLVITIGRESGSAGRQIGQMLASELGIKCYDKELLTLAAKQ
                     SGLCEELFKTHDEKPTNSFLYSLIMDSYSVGYTGGLGYMDMPLNQKVFLAQFEAIKKL
                     AEEESCVIVGRCADYALAEYPGMVSVFICGNEEDKIRHLMDSHNVDRVKAKDIMIKTD
                     KRRASYYNYYSSKRWGDCKSYDICINSSVVGYEGAVQVIKAFADTKMEYLKNKNSQA"
     gene            complement(6546..7460)
                     /locus_tag="ACZPCR_10560"
     CDS             complement(6546..7460)
                     /locus_tag="ACZPCR_10560"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HIR1231342.1"
                     /translation="MKQSYLVPEEFQGERIDKYLSEACCGLTRSYLQKLLKSQLVEVD
                     GKAVKNSYRVSAGETVELEVPEAVEPEIEAEPIPLDILYEDKDIILINKPKGMVVHPA
                     AGHYSQTLVNGLMYHCRGELSGINGVMRPGIVHRIDMDTTGVLIVCKNDFAHNSIAEQ
                     LKVHSITRKYYAIVHGVIGEDEGTVDAPIGRHPVDRKKMSINYKNGKHAVTHYRVLER
                     FKQFTYVECQLETGRTHQIRVHMASLNHPLLGDSVYGPSKCPFKLQGQTLHAGVLGII
                     HPRTGEYMEFSAPLPEYFENLLEKLRKI"
     gene            complement(7541..8059)
                     /gene="lspA"
                     /locus_tag="ACZPCR_10565"
     CDS             complement(7541..8059)
                     /gene="lspA"
                     /locus_tag="ACZPCR_10565"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013272697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HIR1231343.1"
                     /translation="MNQKVRQLLFFAVGLIVSIGLDQWTKALAVAKLKGNQPFVLING
                     VFEFYYSENRGAAFGMLQGRQFLFFIIAAFVLAAAVFVLVRMPSERRFLPLTACLFLL
                     VSGAAGNMIDRISQGYVVDFLYFKLIDFPIFNVADCYVVIATFLLMILIFFVYSEEEL
                     SFLSFKKQRKEG"
     gene            complement(8091..9179)
                     /gene="aroB"
                     /locus_tag="ACZPCR_10570"
     CDS             complement(8091..9179)
                     /gene="aroB"
                     /locus_tag="ACZPCR_10570"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016280840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HIR1231344.1"
                     /translation="MANRMTVHMDEKPVYDILLEQDFSALPKELESFHLEHRKICIVT
                     DSNVAPLYLEEVKELLKPCCSQVISFVFPAGEEHKNLDTVRELYETLILAKFDRNDML
                     AALGGGVVGDLCGFAAATYLRGVSFIQLPTTLLSQVDSSIGGKTGVDFDAYKNMVGAF
                     HMPKLVYENIGALKTLPPEQFSAGMGEVIKHGLIQSNEYYEWILEHKEAIRAMDMDAL
                     EQLVVESNHIKRRVVERDPAEKGDRMLLNFGHTLGHAIEKLKNFELLHGECVALGSIA
                     GMYISAKRGYISMEEMERFASALSWFGIKTAVNGLDIHSVIEATANDKKMDSGVIRFI
                     LLKEVGQAFVDRTVTPEEMEEALQYIFN"
     gene            complement(9288..9890)
                     /locus_tag="ACZPCR_10575"
     CDS             complement(9288..9890)
                     /locus_tag="ACZPCR_10575"
                     /inference="COORDINATES: protein motif:HMM:NF037631.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmH/Sll1252 family protein"
                     /protein_id="HIR1231345.1"
                     /translation="MLTGGYEPAERKIVCFLPSYEEETMEPPIRILEVKPVSPRFAEA
                     LTHRDYLGALMNLGIERSILGDIVINEDGCFIFCLDRMAEYISNELRQVRHTAVFCQR
                     VSALSCQVEQKYEEVRGSIASPRLDSVLAMVYHSSRTKIIPYIQGEKVFIDGRLVTSP
                     SLQLKGGEIVSVRGMGKFQFTGTENETKKGRIFVSARKYC"
     gene            complement(10050..10586)
                     /locus_tag="ACZPCR_10580"
     CDS             complement(10050..10586)
                     /locus_tag="ACZPCR_10580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000917 - division septum assembly
                     [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA];
                     GO_process: GO:0090529 - cell septum assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HIR1231346.1"
                     /translation="MSILNKIMDTMRLNEADDDEDDGYFDEEYEEDERPARRRLFNKQ
                     HNDDYEYDEEPEQRPRFLSRPASSNNKVVPLRRGMEVSLIKPVSMEDSHEICERLLEG
                     KAVVLNLEGIHLEVAQRIIDFTCGATYSMDGNLQKISGSIFIATPSTVELSGDFRELL
                     SNTPSSAGMNVSGLSFHL"
     gene            complement(10583..11287)
                     /locus_tag="ACZPCR_10585"
     CDS             complement(10583..11287)
                     /locus_tag="ACZPCR_10585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HIR1231347.1"
                     /translation="MIKENLEEVREKIRQACQRSGRREEDVTLISVSKTKPVEMLREA
                     YEAGSRDFGENRVQEIMEKYGQMPEDVRWHMIGHLQKNKVRQVIDKAVLIHSVDTVEL
                     AEQIEKDAAKRDLTVDILLEVNVAEEESKFGFRTEEVEAAVMKIKEFPHVHIKGLMTI
                     APFVSNSEDNREVFKKLYQLYVDIRSKNIDNVNMSVLSMGMTGDYEVAVEEGATMIRV
                     GTGIFGARTRNGESRV"
     gene            complement(11308..12711)
                     /locus_tag="ACZPCR_10590"
     CDS             complement(11308..12711)
                     /locus_tag="ACZPCR_10590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HIR1231348.1"
                     /translation="MAKTKKIVPYRKPKNFNIGTLIFTLIFLYLALCVFKYLGRDKIQ
                     FYEVVEGSIVNDKTYTGLILREETVKQAEQSGYVNYYVREGKKAAAGSRIYSLDETGE
                     LEHYLEESQEAGQAFTDENLALLKKKLASLCLSYDDSEFSSVYDEKYSLDASVVELVN
                     FNALDQLDSELETKGIHFQQIYTDQAGIISYAIDSYEGMEPSAVTADSFKKENYKKSV
                     GQAGKLIEAGTPVYKMITSENWSILFPLTEEDKAAYADKDRLQIKFTDDNLTLSGAYS
                     QITGADGGAYGKLDFERFMVQFISDRFAEFEVVSEAEEGLKIPAASVTTKDFFTIPVE
                     FAASGGDESSARTGFYKEVYSESGEASVVFTPAEIYGSTDEYYYVETSEDGAFKNGDY
                     IVKQDSSERYQIGATAPLEGVYNINKGYAVFKKIEKLSGNGEYFTIAKGTDYGLSVYD
                     HIVLDASMVTEGMIIYE"
     gene            complement(12884..>13088)
                     /locus_tag="ACZPCR_10595"
     CDS             complement(12884..>13088)
                     /locus_tag="ACZPCR_10595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="twitching motility protein PilT"
                     /protein_id="HIR1231349.1"
                     /translation="ISQDHDLEQMYFDSFLKLASLEGESIEETFKTLQEISEKYHLTF
                     VLSVSEDASNLPECAKSSVVVSL"
BASE COUNT         3279 a         3445 c         2529 g         3835 t
ORIGIN      
        1 ttataaaatc atatcgcctc atgaaacata agctgttaaa ccgaagcaca ggcgctacat
       61 cttcatccgg aataatccaa atacctttcc aagaatctga acttcatcta caatgatagg
      121 ctccatggaa gagttctccg gctgaagacg atagtggccg ttctccttat aaaaacgctt
      181 aactgtggct gaatcgtcta aaagcgctac cacaatttct ccgttctcag ccgtcacggt
      241 cttctccaca aaaatcaaat caccattaaa aataccggcc tctatcatac tgtcgccctt
      301 tacccggagc ataaatacct ctttatcggg aagcatctct gtgggaattg gaaaataatt
      361 ctcgatgttt tcctgagcta aaagcggcat accggcggca actgttccca aaagaggaac
      421 gttcaccacc tcccggcggg ccagattaaa gcagtcgtca ataatctcta tggttctggg
      481 cttcgtagga tccctgcgta tatatccatt tctctccagc gtctccaggt gggagtgaac
      541 cgaggaggta gactttaaat ttaccgcttc gcaaatttcc ctgacagccg gcggatagcc
      601 cttctttaat atagtttctt taatatattc taatatttcc tgctgttttg gcgtaatttt
      661 ttcctgtgac ataatcaaac ctcccatcgg gtaatcgtaa aacagtgtac tgcccctgat
      721 aatactatat tatcatagaa tggcaaaaaa ggcaaacttt tgttcggatt ttttgcaaaa
      781 tcaattgaca aacgcatgtt cgagatatat aatacagata gttaaagaac atacgttccg
      841 gaacatgcgt ttgttttgtt tttctactca ttttaccata cgaggaggat tttactatga
      901 aaggaaaaag cagaaaaaaa ggaaaacttg ccgaaagggg tgtttcctta tccggatccg
      961 tttattcgcc agacagttgt ctcatccgtc ctaactgtcc tgcagcgaaa attttgttca
     1021 gcgctgctgc gctttttgct ctctgcgtta tactgacgac agtgaatctt ttaagttcac
     1081 aggcagaaga gcagaagagc agtccttacc ataaatacta taccagcatc caaattcagg
     1141 atggagacag cttatggagt attgcagaaa cataccgcac tcattccggc aaaagtgccg
     1201 ccgaatatgt ctgtgactta aaagagatga attccctttc cgaagacacc attcatgccg
     1261 gacattatct gaccatctat tactatgatt ctgtaccaaa gtaattcttt gttctgattc
     1321 tgcatagaac cttagttttc tctcagcttt accttatttc tggcgctgcg gcggcgctca
     1381 tcctctagtg ccgcatagtg cctcttggtc gtatttacgt ctgcatgtcc cagaacgtct
     1441 gctaccaaat aaatatctcc agtttcccgg tacagattcg ttccgtaagt actgcgcagt
     1501 ttgtgaggcg taatcttttt taaaggagct gcagcctggg catatttttt gacaagattt
     1561 tctacgctcc ttacattcag gcgctttttc tgcatagata agaacagagc ttcctcattt
     1621 ccaggggcag gaacgatgtg tctgcgttcc tccatgtagt ctctcagggc cagctctacc
     1681 tcgtctccaa aatagatgat tacttctttt cctcccttgc ggtgaatccg gattccatcg
     1741 acattaaaat cgacatcatt caaattcaat ccgatacact ctgatacgcg gatacctgtg
     1801 ccgagcagaa gcgtcatcaa agccagatcc cttactctgg tctttttatg gtaagctttc
     1861 tgcctttctg tcaaagaatc tccgtcctct accagatcca ggagtcgggc tacttcatca
     1921 atctccagcc ggacaatttc tttttcgtgg agcttaggca gtttcaccag cgcagccggg
     1981 ttcgtctgaa ttcgttcatt tctaaaaaaa tagttgtaaa agctctttag agaggacatt
     2041 tttctggtga gtccccgctc ggtattaatt aaatcttctt tattctctgt agaatggcat
     2101 ttgagaaatt ctaaatattc ctccaaatcc attacaccga tctgatccag aacatctacc
     2161 gtaaaatcgc gtttatcctt atttttccat atcggattcg tttgaatcaa aaagtcaaaa
     2221 aagatactca gatcataagc ataagcaatt cttgtccgcg aagaagtacg aggttcaatt
     2281 ccgcgaaaaa agtcggcgca gaaaggcgga agttcccgga taagctttct gagtttcttc
     2341 gtattttcta tcatttcctg ttcgtggtag gagagtactg ccatgcgaat tcctcctttt
     2401 cattattttc gaatcattgt ttgaagcatt atttcctgtt attattttcg tttacaggcc
     2461 atccgggaat atttccagat gcaactgcat gaaaaaatcg atcctttact cctggggcct
     2521 ctgtgttgat tgatttaatt aaatttttaa caaactctcg ttttgttttt ccgtcaaccg
     2581 gacatggatt tttacataca ggaagctggt aacgattttt gaagccaata atatcagcct
     2641 ccgatacata taaaaatgga cgtattacaa ataaatccat tctgtctaaa tacgtttttg
     2701 gagaaaaggt atgaaaacgt ccctcgtaaa tcagagacag catcatcgtg tcaattacgt
     2761 catctctgtg gtgagcataa gcaattttat tgcagcctaa atcctttgca gctttattca
     2821 aagcgccttt tctcattttt gcgcagagcg cacaggggtt cgattcctgg cgggattcaa
     2881 aaacaatctg gctgatttct gtaggaacca ctgtatatgg aacggaaagt ttctggcaga
     2941 agatttttgc cgcctgcagg tcaaaattgc caaatcctaa atcaactgta acagcacata
     3001 agtcaaaaga cttgggataa aatttctgga gatgtttcat agcatacaat aatgccaagc
     3061 tgtcttttcc tccagaaagt ccaaccgcaa ttttgtctcc gggatcaatc atgtcatatg
     3121 catcaagcgc ctgtcgagtc aggctgagca gtctttgaag tttcatctgt tttgtgtctc
     3181 ctgtaaatca attattataa aaattaaata gctgcgtcaa aagagcagga gtgcagaaac
     3241 ctccaaaaga ggtctgcttt acacatttat aactattcgt gaaagaatag tttatcgaat
     3301 agtttcatgc gttttctttc ttttgactct gcgttgttat tataacacat tttagggggt
     3361 gcgttatgaa gaaattacgt tccgccggtt tggctcttct gttagcctta acctctgcat
     3421 tttctgctct ggcagctccg gcggttcctc ccgcccgggc tccggcagtt tccagttcca
     3481 acgctataga tttctatggc ttaatgtaat gaaaagaccc tgattttctc agggcctgta
     3541 ctgttttatt gtctgattac tctaaaattc tcctgtagtg agtccaagct ctgtcagaaa
     3601 ggctcactgt aacattattg gctcttccgg cgctctcgtg aatgcaaatc atttttccag
     3661 tagccggatc ccagcccaaa aacattacta catgagcctc gtccccagga accactgcaa
     3721 tatcgccagg cttcagttcc tccctgggta tttcagttcc gctggaagcc agactgctgg
     3781 ttcctcctct ggcaacaggc gttcccaggg ctgaccaata tacccagtta atccatccag
     3841 aacaatccag gccttttaag gttcttccca tctgatccgg ctctgtcacg ctgaaaaact
     3901 gatttccgga atagcctggc cgagaagcct tccctccaaa atggtatgga atttttccaa
     3961 cagaatcaag agcgaacgca atcagctttc ttctctcagg cgatatatct tctggcagaa
     4021 gagccatgtg agcttctagt tcctgttttg tcaatgtctt tccaaaagac atttcctctg
     4081 attttaagcc atatttagct tcccaatcca gagatgccag tctgcgtgca gctgcttgtc
     4141 tctcttctgt ccacccggtc cagcctccgt tttcattgtt tgctgagtca gtcttctcct
     4201 cctctgtttc ctgtattgat gcagccagaa aaaacagatt cttttgttcg ttcagccccg
     4261 ttattgtgat cgtaaccacc acatcgacgt ggcctgggca gatagacaaa tcggcggttc
     4321 cagaaccaga actgtttccc tgcgctgctc cattctcctc ggatgcctct ggattcttct
     4381 gttgaggttg ggccgtttct gtctgccctt ctgtttctga aacgctctct tctttcaaag
     4441 cagctgatac ggtctctttt gcctgtgttg tctcggctga agctgaagaa acggattctg
     4501 gtgcggaaac tgattccaaa gccgaagttg attctggcgc tgaaactgat cctgacacag
     4561 attcagctgg cattggttcc tcttttttct caggaacggc cacagcactt tccgcaggat
     4621 tttgacctga ggtttcagat actcctgcgt cgttccccac gttctgggac gaaacgctgg
     4681 cagaggctcc tcctgtctct ccttctgtct gcggcacagt ttcctgtatt cttacactct
     4741 cctgtccgct ctcttttgtc tcatccgcag ttccagactg agcgggcgtg aactctgtct
     4801 cctcctcatc tgtctcctca cagccgtcgc agtaatagac agagcccact gagatatcgt
     4861 attggtgaga taaatcccac aatttcagcg cataggcctc tgatgactgc acgtgatccc
     4921 actggtgaaa ataggaatac acattcgtaa gcgccagtat ttcctttgta ttgctgtaat
     4981 ttgcactctc cgttccatcc ccattgagaa aacggaagcg aatcccggtt ctgtaaggca
     5041 ggcggttcag ttcctggtaa attcggtaca tccagttctg ctctttttca ttaagttcct
     5101 caaacaattc tcctcctgca gatttctggt gaagctccgg accaaaccgg cttaatttct
     5161 gcaaaactgt ctgcagcagt atatctgcag ccgtcttttg agaggcctcc ccaccctttt
     5221 cctcttctgc tgtatcctcc agcggaaaaa ggtaagcaag attgtattct tcaggggaag
     5281 gagcgtatcc gaagctctgc cagaatccat gcagatactc tcccactcct tttaggcatc
     5341 cctgcgccat ggaaaaaaat gttttctcat ctggcagcgt ttccacggac tttttttcct
     5401 gttttccctc ctcctgcttt tcctttttca ggctatgact ggcgcttaag gcttccacat
     5461 acccctttcc agactccttc atccactctg acagcgccgc tggggggact gccagagccg
     5521 ccattgccag aaccgtcagc atatatgttt ttatttcttt tttcttgtgt atcttcatta
     5581 tctgttgtaa caaatcctgt ctgtaaaact cggctgcata cagcctgcct tattacagta
     5641 tcactgatcg gttcttaata gcaacccaaa aagacgaaat tttttcttaa tcttaaatca
     5701 gccgcaggtt ctctggaaat tttagatcag cttcttcttt gaacataaaa aaataaggcg
     5761 gtctcccaaa ggaaaccgcc ctgcagttct aggcctgtga atttttattt tttaagtact
     5821 ccattttcgt gtccgcaaac gctttaatga cctgtacggc gccttcatat cccactacgc
     5881 tgctgttaat gcagatatca tagctcttgc agtctcccca gcgcttgctg gaatagtaat
     5941 tatagtagct ggcgcggcgc ttatctgtct tgatcataat atccttagcc ttcacacggt
     6001 ctacattgtg gctgtccatt aaatgccgga ttttatcttc ctcattgccg cagataaaga
     6061 cagacaccat tccaggatac tctgccagcg cgtaatcggc gcaccgtcct acaatcacac
     6121 aggattcttc ctcagccaat tttttaatcg cttcgaactg agcgagaaaa accttctgat
     6181 tcaaaggcat atccatatat cccagtccgc ctgtatatcc tacagagtag gaatccataa
     6241 taagtgaata cagaaaactg ttcgtcggct tctcatcgtg ggtcttaaac agctcctcgc
     6301 acaggccgct ctgttttgca gccagagtaa gcagttcctt gtcgtaacac tttatcccca
     6361 gttcactggc cagcatctga ccgatttgtc gtcctgcgct tccgctctca cgtcctattg
     6421 taatcacaag attatgtttc atatgaacac tcccttctgt aattccctta agaaatatgg
     6481 ttcatatgca tattatagct caaaacttct gaaaagtcat cactttttaa caaaaatatc
     6541 agcttttata tttttctcaa tttttcaaga agattttcaa aatactctgg gagcggagca
     6601 gaaaattcca tatactctcc ggttcttggg tggataattc cgagaactcc tgcgtgcagc
     6661 gtctgtccct gaagcttaaa cggacatttg gacggtccgt acacactgtc ccctaaaaga
     6721 ggatggttca ggctggccat gtgcacgcgg atttggtgag ttcttcccgt ttccagctgg
     6781 cactccacat aagtgaactg tttaaagcgc tctaaaaccc tgtaatgagt taccgcatgc
     6841 ttaccgtttt tgtaattaat actcattttt ttccggtcga cgggatggcg tccaatgggc
     6901 gcgtctaccg tcccctcgtc ctccccgatc actccatgga caatcgcata atacttccgt
     6961 gtgatggagt gaaccttcag ctgctctgca attgaattgt gggcaaaatc atttttacat
     7021 acaatcagga cgccggtggt atccatatcg atccgatgga caattcccgg gcgcatcacc
     7081 ccgttaatgc cggaaagttc cccgcggcag tggtacatca gaccgttgac cagagtctgg
     7141 ctgtaatgtc cggccgccgg atgcactacc atccccttgg gcttattgat gagaataata
     7201 tccttatctt catataggat atctaacgga atcggctccg cctcgatctc tggctctacc
     7261 gcctcaggca cttccaattc cacagtctct ccagccgata cgcggtaact gtttttgacg
     7321 gcctttccat ccacctccac cagctgggat ttcagcagct tctgcaggta agaccgggta
     7381 aggccacagc aggcttctga caggtatttg tcaattcgtt ctccctgaaa ttcctccggc
     7441 acaagataac tctgtttcaa actttttcct ccgttctcct cagtctcttc tctgcagccc
     7501 tgcagatttc atgctgccgc agctggctgt ctgccgcaat ttacccttct tttctctgct
     7561 tcttaaaaga aaggaaggac agctcctcct ctgaatagac aaaaaagatt aaaatcatta
     7621 aaaggaacgt cgctatcact acataacagt ccgccacatt gaaaatgggg aagtcaatca
     7681 gcttgaaata gaggaaatct accacatacc cctggctgat tctgtcaatc atattccctg
     7741 cagctcccga taccagcaaa aacaggcacg ctgtcagagg cagaaaccgg cgctcagacg
     7801 gcatccggac caacacaaaa acggccgccg ccaatacgaa ggccgctatg ataaaaaata
     7861 aaaactgcct tccctgaagc atcccgaagg ccgctcctct gttttcagaa tagtaaaact
     7921 caaatactcc gttaatcagc acaaacggct gatttccctt cagcttcgca actgccaggg
     7981 cctttgtcca ctgatcaagc ccaattgaca caattaaacc aacggcaaaa aagagaagct
     8041 gtctgacttt ctgattcatg tattcttttc tcctttaacc ggctttacag ctaattgaaa
     8101 atatactgca aagcctcctc catttcctcc ggcgttaccg tgcggtccac aaaggcctgt
     8161 ccgacttcct tcagaaggat gaatcgaatc acaccggaat ccatcttttt atcattggcc
     8221 gtagcctcga tcaccgaatg gatgtcaagc ccgtttacgg cagttttaat gccgaaccag
     8281 gacagagcag atgcaaagcg ctccatttcc tccatggaaa tatatcctct ctttgcagaa
     8341 atgtacatac ctgcaatcga accaagggca acgcattctc catgaagcag ttcaaaattt
     8401 ttaagctttt caatggcatg tcccagcgta tggccgaaat tcaggagcat tctgtctccc
     8461 ttttcagccg gatcccgttc cacaactctc cgcttaatgt ggttgctctc cacgaccagc
     8521 tgttccaggg catccatgtc catggcgcgg atcgcctcct tgtgctccag aatccactca
     8581 taatactcgt ttgactgaat caggccgtgc ttgattacct ctcccatgcc tgcagaaaac
     8641 tgctccggcg gaagggtttt cagggctcca atgttttcgt aaaccagctt tggcatatgg
     8701 aacgcgccca ccatgttttt gtacgcgtcg aaatccacgc ctgtcttgcc accgatgctg
     8761 ctgtccacct gagacagaag agtcgtagga agctggataa aagacacgcc tctcaggtag
     8821 gtagcggcgg caaaaccgca caaatctccc accacgccgc ctcccagggc tgccagcata
     8881 tcgttccggt caaatttggc taaaatcagc gtctcataga gttccctgac tgtgtctaaa
     8941 tttttatgct cctcgccagc tggaaataca aaggatatta cctggctgca gcacggcttc
     9001 aaaagctcct ttacctcctc caaatacaga ggcgccacat tggaatctgt tacaatgcaa
     9061 atttttctat gttccagatg aaaggattcc aattcctttg gaagagctga aaaatcctgt
     9121 tccagaagaa tatcgtaaac cggcttctca tccatgtgaa cagtcattct gtttgccatt
     9181 tctgtcatcc ctttaccgcc ttttgactgt ctgtccagcc agtaaaagca gccctttctg
     9241 tctattttta atactctcta tcgtctgttc cattcagaaa acttttatca gcagtatttt
     9301 ctggcagaga caaagattct gcccttcttc gtctcattct ctgtgcctgt aaactggaac
     9361 ttccccattc cacggaccga tacaatctct cctcccttca gctgaagaga gggggacgtc
     9421 acaaggcgtc cgtctataaa taccttctcc ccctgaatat atgggataat ttttgtcctg
     9481 gagctgtgat acaccatagc aagcacgctg tcaagcctgg gagaggcaat actcccccga
     9541 acttcctcgt atttctgttc cacctggcag gacagggcgg agacgcgctg gcaaaaaaca
     9601 gccgtatgcc ttacctgcct caattcattt gaaatatatt ctgccatccg atccaggcag
     9661 aaaataaaac agccgtcctc atttatgaca atgtccccca gtatactccg ctcgattccc
     9721 aggttcatca gcgcacccag ataatctctg tgggtaagcg cttccgcaaa ccggggactg
     9781 accggtttca cttccaatat acggataggc ggttccatcg tctcctcttc ataggacggc
     9841 agaaaacaga caatcttgcg ctccgccggc tcatagccgc ctgtcagcat aaagcgtaca
     9901 ggcggcagac tccgttccag agaatgaaaa actgtctgtt cattcagatt caaaaaatct
     9961 gtgtatgacg gaatatccct ccggcagcaa aggtctgcca gatccaggat ccgttttttt
    10021 aataattgtt cttccctgtt catagttcct tataagtgaa agctgagacc tgagacgttc
    10081 atccctgcgc ttgacggcgt attggaaaga agttcccgga aatctccgga taattccact
    10141 gtggaaggag tggcaataaa aatactcccg gaaatcttct ggagatttcc atccatcgaa
    10201 taagtcgctc cgcatgtaaa gtcaataatc ctctgggcaa cttctaaatg aattccttcc
    10261 agattcagca caactgcttt tccctctaac agcctctcgc aaatttcatg ggaatcttcc
    10321 atagatacag gcttaattaa ggaaacttcc atgcctcttc ttaacggcac taccttatta
    10381 ttagaagaag ccggccttga caggaaccgc ggtctctgct ctggctcctc atcatattca
    10441 taatcgtcat tgtgctgttt attaaataaa cgcctgcgcg ccggcctttc atcctcttcg
    10501 tattcctcgt cgaagtatcc gtcatcttcg tcgtcatctg cctcgttcaa ccgcattgtg
    10561 tccataatct tgttcagaat gctcatactc tgctctctcc attccttgtc ctggctccga
    10621 aaataccggt gcccactctt atcatggttg cgccctcctc gacggcaact tcatagtcgc
    10681 cggtcattcc catggacagc acactcatat taacattatc aatgtttttg ctccttatgt
    10741 caacatataa ttgatacaat tttttaaaaa cttcccgatt atcttccgaa ttcgatacaa
    10801 atggagcaat tgtcataagc ccttttatgt gaacgtgagg aaactctttt attttcatca
    10861 cagcagcctc cacttcctct gtccggaaac cgaatttgct ctcttcctcc gccacattta
    10921 cctctaaaag aatgtccacc gtaagatccc gcttggctgc gtccttctcg atctgctccg
    10981 ccagctccac ggtgtctaca gagtgaatca gaaccgcttt atcaatgacc tggcgcacct
    11041 tatttttctg aagatggcca atcatgtgcc agcgcacgtc ctccggcatc tgcccgtatt
    11101 tctccataat ttcctgaacc ctgttttctc cgaaatccct ggaaccagcc tcataggcct
    11161 ctctaagcat ttccaccggc tttgtcttgc tcacggaaat cagcgttacg tcttcctctc
    11221 tccgcccgct tctctgacat gcctggcgga ttttctcacg aacctcttct aaattctctt
    11281 ttatcatacc tgcatctcct gttatactta ttcgtagata atcattccct ctgtcaccat
    11341 cgaggcgtcc agcacaatat ggtcgtacac agagagacca taatcagttc ccttagcaat
    11401 tgtaaaatac tccccgttgc cggacaactt ttcaatcttt ttaaaaactg cgtagccctt
    11461 attgatattg tacacgcctt ccaacggagc ggtcgctccg atctgatagc gctcgctgga
    11521 atcctgtttt acaatgtagt ctccattttt gaaggctccg tcctctgaag tctctacata
    11581 ataatattcg tctgtggatc cgtatatctc agcaggcgta aagaccaccg aagcttctcc
    11641 gctctccgaa taaacttctt tgtaaaatcc tgtcctggcg ctgctttcat ctcccccaga
    11701 agctgcaaat tctactggaa tggtaaagaa atccttcgtt gtgacagatg cagccgggat
    11761 cttgagtcct tcctccgcct ctgacaccac ttcaaattct gcaaagcgat cagagataaa
    11821 ctgcaccata aaccgctcaa aatccagttt tccgtaggct cctccgtccg cccctgtaat
    11881 ctgtgagtag gctcctgaca gtgtcagatt atcatctgta aactttatct gcagccgatc
    11941 cttgtctgca tacgccgcct tatcttcctc tgtcaacggg aagagaatcg accagttttc
    12001 agaagtgatc atcttataaa ccggcgttcc cgcctcgatc agctttccag cctgtccgac
    12061 ggatttctta taattttctt ttttaaagga atctgccgtg acagccgacg gttccatccc
    12121 ctcataggaa tcaatggcat aggatataat gcctgcctga tccgtgtaaa tctgctgaaa
    12181 gtgaattccc tttgtctcaa gttctgaatc cagctgatcc agagcattaa aattcaccag
    12241 ctccacaacc gacgcatcca gggagtattt ttcgtcgtag acagaagaaa actccgaatc
    12301 gtcataagac aggcagagag acgccagctt ttttttcagc agagccagat tttcatctgt
    12361 aaaggcctgt cccgcctcct ggctctcctc caggtaatgc tccagttctc cagtctcatc
    12421 cagggaataa atgcgggaac ctgccgccgc cttctttcct tccctcacat agtaattcac
    12481 atatcctgac tgctctgcct gtttcaccgt ctcctcgcga agaattaatc ctgtatatgt
    12541 tttatcattg acaatgcttc cttcaacaac ctcgtaaaac tgtatcttat cccgtccaag
    12601 gtacttaaac acacaaagag ccagatagag aaagatcagg gtaaatatca gagtacctat
    12661 attgaaattc tttggttttc tataaggtac tatcttttta gtcttggcca tgatgctaac
    12721 cggtctcctt tccctatgta ttataaaagg aatcgcccaa aagtgcaagg taattcagga
    12781 aatggctgga aaagacaaag agcgaaagag ggaagactgc cgtctgcagt tctcccctct
    12841 tttgtactgt catatgtaat ttttctcaaa tacagccgct gtcttataaa gaaacgacta
    12901 cgcttgattt agcgcactct gggagattcg acgcgtcctc agatacgctg agaacaaatg
    12961 tgagatggta tttctcgctg atctcctgca gtgtcttgaa ggtctcctca atactttctc
    13021 cctctaagga agccagcttt aagaagctgt cgaagtacat ctgctccagg tcatgatcct
    13081 gcgaaata
//
LOCUS       DBMDUW010000067        12914 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_2533_length_12914_cov_4.623585, whole genome shotgun sequence.
ACCESSION   DBMDUW010000067 DBMDUW010000000
VERSION     DBMDUW010000067.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 12914)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 12914)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12914
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2533_length_12914_cov_4.623585"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            250..1263
                     /locus_tag="ACZPCR_10600"
     CDS             250..1263
                     /locus_tag="ACZPCR_10600"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HIR1231350.1"
                     /translation="MMSDVMETALKKPIQTGEFRKRPVEPAWRCPAGYVYRLVELDAC
                     TMEYLTPEDAVTGRVILQLHGGGYIGPMKNIYRRFAVRYSKLSYGADVLSVDYRVAPE
                     HPFPAALEDAAAAYRWLLEEKGYEPDKIVVAGDSAGGGLALSLIMYLKDQKLPLPGGI
                     ITMSPWTDVTLSGESYESNYEIDPLFGNSRENMLYQCSYIGDADPKNPYLSPLFGDFS
                     DLPPMLMQAGEYEVLLSDTLQVSEKAKKAGVKVRTSIYAGMFHVFQMGLDLIPESREA
                     WEEVGEFLRIIYGIQRTDDGKPVKKVKNRRPEADARARELLKAMIRGELSGGGKEQEG
                     EKQ"
     gene            1260..1739
                     /gene="rlmH"
                     /locus_tag="ACZPCR_10605"
     CDS             1260..1739
                     /gene="rlmH"
                     /locus_tag="ACZPCR_10605"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HIR1231351.1"
                     /translation="MKITVIAVGKIKERFFEEAIAEYSKRLSRYCRLEIIQVADEKTP
                     DRASEAVERQIKDKEGERILSHVKDSAYVIALAIEGKMLDSEALAEKINSLGLSGESH
                     IQLVIGGSLGLSKKVMDRADFALSFSKMTFPHQLMRVVLLEQIYRSFRIIEGAPYHK"
     gene            1748..2176
                     /locus_tag="ACZPCR_10610"
     CDS             1748..2176
                     /locus_tag="ACZPCR_10610"
                     /inference="COORDINATES: protein motif:HMM:NF024863.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDSL-type esterase/lipase family protein"
                     /protein_id="HIR1231352.1"
                     /translation="MAASMYKGRVVLCTLTLCFGDSNTFGYDAGSRLGRQLEERERWP
                     EVFAGLIGWDLVNEGMNGREIPAGWFLERFDKILEEDAPFDVLAVMLGTNDILNSFQP
                     DAAEAGRNMEAFLLHALNHPQIQGEGQKLFARKLFEALSE"
     gene            2495..3520
                     /locus_tag="ACZPCR_10615"
     CDS             2495..3520
                     /locus_tag="ACZPCR_10615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HIR1231353.1"
                     /translation="MAQEYYYGQMSREEQEAYRGMFAGFCEIASEISVRRLDNRQLSD
                     VFFRLRLDHPEIFYVESFQYRFTEDSQYVRMKPSYMFEKKKIKEHQKALEGRINRLTR
                     QAQGKTKEEEEQFIHDFICENVTYDKLKKQYSHEIIGPLQQGVGVCEGIAKTVKILCD
                     RLNIECIIAVSEAAPDQGVKYRHAWNVVKPGKTWYHLDATFDNSLGRYGAARFDYFNL
                     GDRELFRDHQKLLYPVPACPDSGSFYYREQRLSLTKEEDVARRLKTALRKKQPYFVFH
                     WRGGKLNRELVRFFYEEACRTAEEKGKFAALSVNVPQSVIEIAIRDRQAEKEIQEEEA
                     NEGELTE"
     gene            3552..4844
                     /locus_tag="ACZPCR_10620"
     CDS             3552..4844
                     /locus_tag="ACZPCR_10620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4272 domain-containing protein"
                     /protein_id="HIR1231354.1"
                     /translation="MRFFIKKRNAPRYEAGELFFCREAQGRQIADRISEMIKSPSEKE
                     GGAVRFQCQGVEFSFAAFGIEDEGEARIYARQELSGVQGYLRNLETVYGNVKRHLLYT
                     IGQCGSVVRVHYSFSRKSERADREKILLAENRMNEILKELRGVRTKGGSALAGPDGRM
                     ILDENGNSKVKNYLPLLEERSQEEGTEEKACLKEALARRKKSVMQLRRRQIYTPLSLP
                     VIETEREAGRRTKHQICGRAAALLTVSLYSECLLGEGMTPPEAGAFVRDIAGRFRAEE
                     FFSPSEKAYLRDSCPDPRTQIQFSWQYENLYVMEWALGLFERLDWPENICSVEECAAK
                     IREFCSLEEFERSVSLRPERELLDAADLYYRLHWACRDAAANGYPLPEKVLSEAAAER
                     RRGLFWAAGCRTAPGETPGKKSGEMPEGDGWDQTDLTT"
     regulatory      4907..5042
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
     gene            5210..6343
                     /locus_tag="ACZPCR_10625"
     CDS             5210..6343
                     /locus_tag="ACZPCR_10625"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HIR1231355.1"
                     /translation="MIEFKHVSKTFHGKKIIDDISFQIPDGEFVVLLGESGCGKTTTL
                     KMINKLILPSEGTVEINGRDIAHMDTIALRRRMGYVIQQIGLFPHMTIRENIEIIARM
                     KSKDRDRMEENAIRLMNMVNLDPATFMDAYPSEMSGGQQQRAGVVRAFMAEPEIILMD
                     EPFSALDPITRTQIQTALIDMQTAMKRTIVFVTHDMDEAIKLADRICIMEEGKITQFD
                     TPENILKNPANDFVRNFIGPKRIWTSPEYIKTRDIMITDPVCCHPKMPIFKCIETMGR
                     KKVDTLMLTDQKGRLFGVLFAESLIGVHDIKKPAEDFMYREFTSVGPDSSIVDLLTLF
                     DEHHLSTLPVVNSQGIIEGLITRSTLINTLSRQFIADAGKEES"
     gene            6343..7932
                     /locus_tag="ACZPCR_10630"
     CDS             6343..7932
                     /locus_tag="ACZPCR_10630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006569067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HIR1231356.1"
                     /translation="MGVMEGMKELLNYFVSSKEEVLSLLIEHIELTVLALLAAILIGV
                     PLGILISYIRPASKPVLAFANIVQAVPSMALLGLAIPVFGIGMKPAIFLVVIYSLLPI
                     IKNTYAGLMNINEQMLEAAEGIGLTKSQILFKVRLPMALPVIMTGVRISAVSAVGLMT
                     LAAYVGGGGLGYLVFSGIRTVSNVMILAGAIPACILALLVDRVFAAIETIVTPVSLLD
                     GKNKDEKRRRKKREMFVIATAVVLLIALLFTSLFQTKKTADIRIASMDFTENEIFAYM
                     LSESIERELGLDVETTPDLGAGSVCMSSIQSNEIDGYVDYTGTLYVNILKNPASSDVE
                     QVYQDSVKGMKEQYGLEVLNSLNVNNTYTLSTTKELAEQYSLKTISDLKSLPQPVTIC
                     STLAFMNREDGLLGVEDRYGFQFDKKGVDGSARYTALMNGEGQVIDAYSTDGLLKKFD
                     LAVLEDDAGVFPPYYAVPVFRGEIMEKYPEIREITEQLASVLSTDVMAGLNYLVDEEG
                     QKPQDVAHEFLQENLPEYASK"
     gene            8067..9062
                     /locus_tag="ACZPCR_10635"
     CDS             8067..9062
                     /locus_tag="ACZPCR_10635"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007714030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase"
                     /protein_id="HIR1231357.1"
                     /translation="MNYYLAPMEGITGYIYRNACGRHFGGVKKYFTPFLSPHMRKAMT
                     SREKNDILPEHNQGIYVVPQILANNGDAFCKALEILEDLGYREVNLNLGCPSGTVVSK
                     GRGSGFLAADRREALSQFLDQIYSCSERRGMKISIKTRLGMEKPEEFEELLSLYLCFP
                     VSELVIHPRVQKDFYKNTPSREAFSLAVQAAGQQGKTEDWICYNGDIFSPQAAEKLSK
                     EFPGTASVMLGRGMIANPGLAGSLSDQDARMTKEEFRSFHDEILEGYREIMSGDRNAL
                     FKMKELWSYQMTLFPGCEKQAKKIRKAGTMDSYLAAVDELFETGNFCPERYFEGF"
     gene            9202..10293
                     /gene="rsmH"
                     /locus_tag="ACZPCR_10640"
     CDS             9202..10293
                     /gene="rsmH"
                     /locus_tag="ACZPCR_10640"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007861864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000154 - rRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HIR1231358.1"
                     /translation="MDQREEKQVQSKGEGEGMQTPHKRRVRYKGTHPRSYQEKYKELN
                     PEKYKDTVERVIQKGGTPAGMHISICVNEILDFFDIQPGQTGVDATLGYGGHTRRMLE
                     KLQGQGHIYGLDVDPIESEKTKKRLLDAGYGPDILTVRLMNFAQLDQLAEEKGPFDFI
                     LADLGVSSMQIDNPERGFTYKYEGPLDLRLNPEKGATAAERLREIDREEFCGMMIENS
                     DEPYAEEISQEVFNRFRRGQAVETTTQLKEAIEAALSFIPEKERKEAVKKSCARVFQA
                     LRIDVNSEFEVLYAFLEKLPGALKEGGKAAILTFHSGEDRMVKRSFKQLKKQGVYREI
                     SEEVIRPSAEECARNSRARSTKMRWAVKA"
     gene            10420..11415
                     /gene="spoIIIAA"
                     /locus_tag="ACZPCR_10645"
     CDS             10420..11415
                     /gene="spoIIIAA"
                     /locus_tag="ACZPCR_10645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007860499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HIR1231359.1"
                     /translation="MAEKKAGQAELLQIFPFHVIEILMKTADDWEEVQELRLRSQKPL
                     FITVKGQEYAVGKEGGLLSVSSADRLKENLSAVCMISQKDIEQTVECAARHSLYAFEE
                     QIRQGFLTVAGGHRIGVIGKAVSERREIRTIKPIAGLNIRIAHEKKGCSDRILHFLAD
                     PAQGEWLSTLLVSPPCCGKTTLLRDIVRNISDGCGYMEGRTVGIVDERSEIAACFQGV
                     PQNDVGIRSDVLDGCPKAEGMMMLIRSMSPRVVAADEIGGKGDLEAIQYAAGCGCSLI
                     AAAHGSSMEELAAKPMFQELFRQQIFRRFVFLSRRKGPGTVERILDHKGCELYVS"
     gene            11405..11926
                     /locus_tag="ACZPCR_10650"
     CDS             11405..11926
                     /locus_tag="ACZPCR_10650"
                     /inference="COORDINATES: protein motif:HMM:NF021090.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HIR1231360.1"
                     /translation="MFLKVLGAFLVVLSCSRLGVYMAARLSERRGLLKKIRVMVIHLR
                     GEILYANAPLYEGFQKAGRRTGGREGLLFETVSEQLLKEQGKEFFAIWQEAVTSYLPQ
                     TPLTKEEGEQLLAFGEHLGYLDREMQERTLSLYLEELEREMEELNQEIAQKGRLYTSA
                     GILTGLFLAVIFI"
     gene            11978..12172
                     /gene="spoIIIAC"
                     /locus_tag="ACZPCR_10655"
     CDS             11978..12172
                     /gene="spoIIIAC"
                     /locus_tag="ACZPCR_10655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006779097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HIR1231361.1"
                     /translation="MGVSLIFRIAAVGILVSVICQVLKHSGREEQAFLTSLAGLVLVL
                     FWMVPYIYELFETMKELFAL"
     gene            12208..12672
                     /locus_tag="ACZPCR_10660"
     CDS             12208..12672
                     /locus_tag="ACZPCR_10660"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231362.1"
                     /translation="MTGEELRRRGFLYFEGIREGLENFEYEIAAMDHAQALLHFRKLR
                     EEYGADNSFLDFYLFSLKEEEREKAESALNEEELEAVRAWEKKAGFPRGDQVIFPMDD
                     ALLRAAVVLNETGMLFSTMYFAREGGKQGEKAVQAETWWGNFNGEYVRFYRR"
BASE COUNT         3446 a         2732 c         3928 g         2808 t
ORIGIN      
        1 taccgagttc cctataagaa gaattataaa gaaaaaataa gctcaggaaa acattttcat
       61 aacgttttgt gtctgagcga agcgaaagga atgaatataa cgatgaacag cagacagaat
      121 aaaagacaga agaacagaca gaaaaagaga gaaaaaccga aacgcctggc aggggacaaa
      181 agaagagaaa acagaaagag aaccgaaaaa cgggagaaag tcagcgctat tgggcgtctg
      241 accagggaaa tgatgagcga cgtgatggag acggcgttaa aaaaacctat ccagacaggc
      301 gagttcagaa aacgccccgt ggagccggcc tggagatgtc cggcaggata cgtttacaga
      361 ctggtggagc ttgatgcctg tactatggaa tatctgacgc ctgaggacgc ggtgaccggg
      421 cgggtgatcc tgcagcttca cggaggcggc tatatcggcc ctatgaaaaa tatttaccgc
      481 cgctttgcag tccgctattc gaagctaagc tacggggcag acgtgctgag cgtggactac
      541 cgggtggcgc cggaacatcc atttcctgcg gctcttgagg acgctgcggc cgcttaccgg
      601 tggcttctgg aggaaaaggg ctacgaaccg gacaagatcg tggtcgcagg ggactctgcc
      661 ggaggagggc tggccctgtc ccttattatg tatttaaagg atcagaagct tcctcttcca
      721 gggggaatta tcaccatgtc tccctggaca gacgtgacgc tcagcgggga atcctatgag
      781 agcaactatg agattgatcc gctgtttgga aattccaggg aaaatatgct gtatcagtgc
      841 agctacatcg gggatgcgga cccgaagaat ccttaccttt cccctctgtt tggagatttt
      901 tcagatcttc cccccatgct gatgcaggcg ggggagtatg aggtgctgtt aagcgatacg
      961 ctgcaggtgt cggagaaggc gaaaaaggca ggcgtgaagg tgcgcacctc catttacgcc
     1021 ggcatgttcc acgtctttca gatgggcctg gacctgattc cagagagccg ggaagcctgg
     1081 gaggaggttg gagaatttct gaggattatt tacggaattc agagaacaga cgacggaaag
     1141 ccggtgaaaa aggtgaaaaa cagaaggcct gaggcggatg cgagggccag ggagctgtta
     1201 aaggccatga tacgaggaga gctttccggc ggcggaaagg aacaggaagg agaaaaacag
     1261 tgaaaattac ggtaattgcg gtaggaaaaa ttaaagagcg tttttttgag gaggctatcg
     1321 cagagtattc caaacggctt tccaggtact gcaggctgga gatcatccag gtagcggatg
     1381 agaagacgcc ggatcgggcc agcgaggcgg tggaaagaca gattaaggac aaggaggggg
     1441 agcggatttt aagccatgta aaggacagcg cctatgtgat agccctggca attgagggga
     1501 aaatgctgga ttccgaggcg ctggcagaga aaataaactc cctgggcctt agcggagaaa
     1561 gccatatcca gcttgttatc ggcggctctc tggggctgtc taagaaggtg atggatcggg
     1621 ccgattttgc tctgagcttt tctaagatga cctttccaca tcagctgatg cgggtggtgc
     1681 tgctggagca gatttacaga agcttccgga ttattgaggg ggcgccgtat cacaaatgat
     1741 aaaacgaatg gcagcgtcaa tgtacaaagg gcgtgttgtc ctttgtacac tgacgctatg
     1801 ttttggagat tccaatacct tcggctatga cgccggttca aggctgggaa ggcagctgga
     1861 agagagggag cggtggcctg aggtatttgc agggctgata ggctgggatc ttgtaaacga
     1921 gggcatgaac gggcgggaga ttcctgcggg ctggtttctg gaacggtttg acaaaatttt
     1981 ggaggaggac gccccctttg acgttctggc agtgatgctg gggactaacg atatcctgaa
     2041 ttcctttcag ccggacgccg cggaggcagg acggaacatg gaagcctttc ttttgcacgc
     2101 gctgaaccat ccccagattc agggagaggg ccagaagctg tttgccagga agcttttcga
     2161 ggcgctttca gaataataac aggggccgga ttccttcccg taattatgtg ggagaggcag
     2221 gactttctgg ttcaattccg gcagcgcggc gattctttta gcgggctcat ggcaggaatt
     2281 gacatttttt agaagatatg aaataattac gagagtgtat atttttgtgc ggtatttacc
     2341 aatggagaag gatgaaattt gacattgtga acccccagcc tccatccgga agagcagacg
     2401 tttatcagat tctgccgcca ggcagaaaag aagagagcga tggcaggtaa aaatggaagc
     2461 cggacaggag aggaacagga ggaatgaaac gcccatggcg caggaatatt actatggaca
     2521 gatgagccgg gaggaacagg aggcgtaccg cggcatgttc gccgggttct gtgaaatcgc
     2581 ttcggaaatt tccgtaagga gactggacaa ccgccagctg tccgacgttt tcttcaggct
     2641 ccggctggat catccggaga ttttttatgt ggagagtttt cagtaccggt ttacagagga
     2701 ctctcagtat gtgagaatga agccgtccta tatgttcgaa aaaaagaaga taaaggaaca
     2761 tcagaaggca ctggagggca gaatcaaccg cttaacgcgg caggcccagg ggaagacgaa
     2821 ggaggaggaa gagcagttta tccatgattt tatctgtgaa aacgtcacct acgacaaatt
     2881 aaagaaacag tactcccacg agattatagg ccctctgcag cagggggtgg gggtgtgcga
     2941 gggaatcgca aagaccgtga aaatcctctg cgaccgtcta aatatcgagt gtatcatcgc
     3001 tgtcagcgag gccgctcccg atcagggcgt caagtaccgg cacgcctgga atgtggtgaa
     3061 gcctgggaaa acctggtacc acctggacgc tacctttgac aactctctgg gcagatatgg
     3121 ggccgcccgg tttgactatt tcaatctggg agacagggaa ctgttcagag accaccagaa
     3181 gcttctctac cccgttccgg cctgtccgga cagcggcagc ttttattaca gagagcagag
     3241 actttccctg accaaggagg aggacgtggc caggcgtctg aagacggcgc tcaggaaaaa
     3301 acagccttat ttcgtatttc actggagagg cggaaaactg aaccgcgagc tggtgcgctt
     3361 tttctacgag gaggcctgcc ggacggcgga ggaaaaggga aagtttgccg ctctctcggt
     3421 gaacgtgccc cagtctgtga ttgagattgc catcagagac agacaggcgg agaaggagat
     3481 ccaggaagag gaagccaatg agggagagct gacagaataa tagcgcctgg gacggcgcgc
     3541 aggaggaagc tatgagattt tttatcaaaa aaaggaatgc gcccagatat gaagcggggg
     3601 agcttttctt ctgccgggag gctcagggaa gacagatagc agaccggatc tcggagatga
     3661 taaagagtcc gtcggaaaaa gagggcggcg ccgtccgctt tcaatgccag ggcgtagagt
     3721 tttcctttgc agcgttcgga atagaggacg agggagaggc ccggatctat gccaggcagg
     3781 agctgagcgg ggtgcaggga tatctgcgga atctggaaac ggtgtatgga aacgtaaaac
     3841 gccatctcct gtacacaatc ggacagtgcg ggagcgtagt ccgggttcac tattctttca
     3901 gccggaaaag tgagagagcg gacagggaga aaatccttct tgctgagaac aggatgaacg
     3961 agattctgaa ggagcttcga ggcgtccgga ccaaaggagg aagcgccctg gcagggccgg
     4021 acggcagaat gatcctggat gaaaatggaa acagcaaggt aaagaactat cttcctctgc
     4081 tggaggagag aagccaggaa gaggggacgg aagaaaaggc ctgcctgaag gaggctctgg
     4141 ccaggcggaa aaaaagcgtg atgcagctga gacgccggca gatttatacg cctctgtccc
     4201 tgcctgtgat agagacggag agggaggctg gcagaagaac aaaacatcag atctgcggga
     4261 gagccgccgc gctgctgacc gtatccctat actccgaatg tcttctgggg gagggaatga
     4321 cgcctcctga ggcaggagcc tttgtacggg acattgcagg gcgattccgg gcggaggaat
     4381 ttttttcgcc gtctgagaaa gcttatctga gggacagctg cccggatccc aggacgcaga
     4441 ttcagttttc ctggcagtat gaaaacctgt atgtgatgga gtgggcgctg ggcctgtttg
     4501 aaaggctgga ctggccggag aacatctgca gtgtggagga atgcgcggca aaaatcaggg
     4561 agttctgttc gctggaggag tttgagcgca gcgtcagcct ccggccggaa cgggaacttt
     4621 tagacgcggc ggatctgtac taccgccttc actgggcctg ccgggacgcg gcggccaacg
     4681 gctatccgct tccggaaaag gtgctttcag aggcagccgc agagagacgc cgcgggctgt
     4741 tctgggcagc cggctgcagg acggcgccgg gagagacacc aggaaagaaa tcgggagaga
     4801 tgccggaggg agacggctgg gatcagacgg atttaacaac ttaacagaaa aattaagata
     4861 aactttattg ttttcaggaa ttatttattg tataatagca tacaatcaat gcagaacgtc
     4921 gaatgccgtc agccgcggca gcgggagaac caatcttttg gggtgaattg gcaggctttg
     4981 ccataggaaa ccttcttttc cgaatccgtc agctaatctc gcagacattg gaaggatttg
     5041 cgtattggca gtatgtgtaa tttcagtgcg tttagatgcc tattttagat gtctatttca
     5101 gaaaaacctt tcgccgcctg ctttcacagg cggttttgct tttctgtatt gtgtcacttc
     5161 aggcggaccg gacggtccat gggaaccgaa catgcaggag ggtgatccaa tgattgaatt
     5221 caaacatgtt tccaaaacgt ttcacggcaa gaaaataatc gacgacatca gttttcagat
     5281 tccggacgga gaatttgtgg ttctgttagg agagagcgga tgcggaaaga caaccacgct
     5341 taagatgatc aacaaactga ttcttccgtc agagggcaca gtggagatta acgggcgtga
     5401 tatcgcccat atggatacga ttgcgctgcg caggcggatg ggatatgtga tccagcagat
     5461 cggcctgttt ccgcacatga ctatcaggga aaatatcgag attatcgcca ggatgaagtc
     5521 caaggacaga gatcggatgg aggagaacgc catccgcctg atgaacatgg taaatctgga
     5581 tccggccacg tttatggacg cgtatccgtc agaaatgtcc ggcgggcagc agcagagagc
     5641 gggcgtggtc agggcgttca tggcggagcc ggagatcatt ttgatggatg agccgttttc
     5701 cgccctggat cccattacca gaacccagat tcagacggct ctcatcgaca tgcagacggc
     5761 tatgaagcgg acgattgtgt tcgtaaccca tgacatggac gaagccatca agctggcaga
     5821 ccgcatctgc attatggagg aaggaaagat tacccagttt gatacgccgg aaaatattct
     5881 caagaatccg gccaatgatt tcgttcggaa ctttatcggt ccgaaacgta tctggacttc
     5941 accggagtac ataaagacca gggacattat gattacggat ccggtgtgct gccacccgaa
     6001 gatgccgatt ttcaagtgta tcgagaccat gggacgaaaa aaggtcgaca ctctgatgct
     6061 gacggaccag aagggcaggc tgttcggcgt tctgttcgcc gagtccctga tcggagtcca
     6121 cgatatcaag aagccggcag aggattttat gtatcgggaa tttacctccg tagggccgga
     6181 cagttccatt gtggatctgc tcactctgtt tgacgagcac catctgtcca cccttccggt
     6241 tgtcaacagc cagggaatca ttgagggact gattacgaga agtacgctga ttaatacgct
     6301 gagccgtcag tttattgcag atgcaggaaa ggaggagtca taatgggagt aatggaagga
     6361 atgaaggaat tattgaacta ttttgtctcc tcaaaggaag aagttctttc tctgctgatc
     6421 gagcacattg agctgacggt gctggcgctt ctggccgcca tcctgatcgg agtgcctctg
     6481 ggcattctga tttcctatat ccgcccggcc agcaagccgg tgctggcctt cgccaacatt
     6541 gttcaggcag tgccaagcat ggcgctgtta ggtctggcta tccccgtgtt tggaatcggt
     6601 atgaagccgg ctatctttct ggtagtgatt tactctctgc ttccgattat caagaatacc
     6661 tacgcggggc ttatgaatat taatgagcag atgctggagg cggcggaagg aatcggactg
     6721 acgaaaagcc agattttatt taaggtaaga cttcccatgg ctctacctgt tatcatgacc
     6781 ggtgtgagaa tttccgcagt ttccgcagtg ggactgatga ctctggcagc ctatgtgggc
     6841 ggcggcggac tgggatatct ggtattttcc ggaatcagaa ccgtcagcaa cgtgatgatc
     6901 ctggcaggcg ccattccggc ctgtatcctg gccctcttag tggaccgggt atttgcggca
     6961 attgagacga ttgtgactcc tgtcagcctg ttggatggca agaataagga tgagaagcgc
     7021 agacggaaaa agagagagat gttcgtcatt gccacagcag tagttctgct gattgccctt
     7081 ctgtttacca gcctgttcca gacgaagaag acggctgata tcagaattgc cagcatggac
     7141 tttacggaga acgagatttt tgcctatatg ctttctgaat ccatagagag agagctgggg
     7201 ctggacgtgg agactactcc ggatctggga gccggttccg tctgcatgtc ttcgattcag
     7261 agcaatgaga tcgacggtta tgtcgactac acgggaacgc tctatgtaaa tattctgaag
     7321 aatccggcca gctctgatgt ggagcaggtt taccaggatt ctgtaaaggg catgaaggag
     7381 cagtacggcc tggaggtatt aaattctctg aatgtgaaca atacctacac cctttctacc
     7441 acaaaggagc tggcagagca gtacagttta aagacgatca gcgacctgaa atccctgcct
     7501 cagccggtga caatctgctc cacgctggcc tttatgaacc gggaggacgg ccttctggga
     7561 gtggaggaca ggtacggctt ccagtttgat aagaagggcg tggacggttc cgcccgctac
     7621 acagctctga tgaacgggga aggacaggta atcgacgcgt attccaccga cggactgttg
     7681 aagaaattcg atctggcagt gctggaggac gatgcgggcg tatttccgcc ttactatgca
     7741 gttcctgttt tccggggaga aatcatggag aaatatccgg aaatcaggga gattacagag
     7801 cagctggctt ctgtgctgtc cacagacgtt atggcgggac tgaattacct ggtggacgag
     7861 gagggacaaa agcctcagga tgtggcccat gagttccttc aggagaacct gccggagtac
     7921 gcgagcaaat agcgggggac acatggcata aaaagaacag ggagaagctt tgcagctgcg
     7981 ggaggagacg ccgaagccgc agagcttctc cctaatttgt gaaaaaacga aagaggcgca
     8041 gcgcgccgga aaggagcaga aaaaagatga attactattt agcccccatg gagggaatta
     8101 cgggatatat ttacagaaat gcctgcggca ggcattttgg gggagtgaag aaatatttca
     8161 ctccttttct ttcgccgcat atgaggaagg ccatgacgtc cagagagaaa aacgatattt
     8221 tgccggagca taatcaaggg atttatgtgg ttccgcagat tctggccaac aacggggacg
     8281 ccttctgcaa ggcgctggag attctggaag atttaggata cagggaggtg aacctgaatc
     8341 tgggctgccc ctccggaact gtggtgtcca agggaagagg atccggattt ctggcagctg
     8401 acaggcggga ggcgctgtct cagtttttag atcagattta cagctgctct gaacggcggg
     8461 ggatgaagat ttccattaag acgcggctgg gaatggaaaa gccggaggag tttgaggagc
     8521 ttctcagcct gtacctttgt tttcctgtga gcgagctggt gattcacccc agagtgcaga
     8581 aggacttcta taagaatacc cccagccggg aggcgttttc tctggctgtg caggcggccg
     8641 ggcagcaggg aaagacggaa gactggatct gctacaacgg ggatattttc agcccgcagg
     8701 cggcggagaa actgtcaaag gagtttcccg gcactgccag cgtgatgctg gggcggggca
     8761 tgattgccaa cccggggctt gcgggaagcc tgtcggatca ggacgccaga atgacaaagg
     8821 aggagttccg aagcttccac gacgagattc tggaaggata ccgggagatc atgtcagggg
     8881 atcggaacgc gctgtttaag atgaaagaac tgtggagcta tcagatgact ctgttccctg
     8941 gctgtgagaa gcaggcgaaa aaaatacgga aggcaggaac catggacagc tatctggcgg
     9001 cagtggacga gctgtttgaa acgggaaact tctgtccgga acgatatttt gagggatttt
     9061 aagggaagct gtcagggctt tcagcctcct ctttccgttc taaacggcat gacagaacct
     9121 gcaatatacg ctataataaa caaaaaccag aaacttaacg aacaccataa aatacagcag
     9181 aatgtaagga gaacagacac tatggatcag agagaggaaa agcaggttca gagcaaagga
     9241 gagggagaag ggatgcagac tccccacaag aggagagtgc gctacaaggg cacccatccc
     9301 agaagctatc aggagaaata taaggagtta aaccctgaaa aatacaagga tacggtagaa
     9361 cgggtgattc agaagggcgg aacgccggcg ggcatgcata tttctatctg tgtgaatgag
     9421 atcctggact tttttgatat ccagccaggg cagacaggag tggacgctac cctgggatat
     9481 ggagggcaca ccagaagaat gctggaaaag ctgcagggac aggggcatat ctacgggctg
     9541 gacgtggatc cgattgagtc tgagaagacg aaaaaacgcc ttctggacgc aggatatggg
     9601 ccggatatcc ttacggtacg cctgatgaat tttgcacagc ttgatcagct ggcagaggag
     9661 aagggcccct ttgattttat tctggcagat ttgggcgtgt cttccatgca gattgacaac
     9721 ccggagagag gatttaccta taaatatgag ggacctctgg atctgcgcct gaatccggag
     9781 aagggggcca cggcggcaga gcggctccgg gagattgaca gagaggaatt ctgcggcatg
     9841 atgatagaaa attccgatga accttacgcg gaggagattt cccaggaggt tttcaaccgc
     9901 ttccgcagag gacaggcggt ggaaacgaca acacagctga aggaagccat tgaggcggcc
     9961 ctgtccttta ttccggagaa ggagcggaag gaagcggtga agaaatcctg cgccagggtg
    10021 tttcaggctc tccgcattga tgtaaacagc gaatttgagg tgctgtacgc ttttctggag
    10081 aagcttccgg gcgctttaaa ggaaggcggc aaggcggcta ttttaacctt ccactcaggc
    10141 gaggacagaa tggtgaaacg ctcttttaag cagctgaaaa agcagggtgt ttaccgggaa
    10201 atttcagagg aggtgatccg tccgtccgca gaggagtgcg ccagaaacag cagggcaaga
    10261 tctacaaaaa tgcgctgggc agtgaaggcc tgagaaaaaa cagaactgaa aagggaacat
    10321 gccaaaaaat atgcgatttt ctcataatct gcctgtcccg gcatatatat ggactaagac
    10381 agacggcgag aggccgattc ttaggggagg cggcgagaga tggcagaaaa aaaggcagga
    10441 caggcagagc ttttacagat ctttcctttt catgtcatag aaattcttat gaagacggct
    10501 gatgactggg aagaggttca ggagctgcgg ctgcgaagcc aaaaaccgct gtttattact
    10561 gtgaaggggc aggaatacgc agtggggaaa gagggagggc tgctctccgt ttccagcgca
    10621 gaccgtttaa aggagaacct ctctgcagtc tgcatgattt ctcagaagga tattgaacag
    10681 acggttgaat gcgcggcacg ccattccctg tatgcctttg aggagcagat ccgccaaggc
    10741 tttctcactg tggcaggagg ccacagaata ggagtgattg gaaaagctgt gtcagaacgc
    10801 agggaaatcc gcaccatcaa gcccattgcc ggcctgaaca tccgcattgc ccacgaaaaa
    10861 aagggatgtt cagataggat tctgcatttt ctggcagatc cggctcaggg ggaatggctg
    10921 tctactctgc tggtatctcc gccatgctgt ggaaaaacga cgcttttgag ggatattgtg
    10981 agaaatattt cagacggctg tggatatatg gagggcagaa cggtaggaat tgtggatgag
    11041 agatcggaaa ttgcggcttg ctttcagggg gttccccaga acgatgtggg gatccgcagc
    11101 gacgtgctgg acggctgtcc aaaggcagaa ggcatgatga tgctgattcg ctccatgtct
    11161 cccagagtgg tggcggcgga cgaaataggg ggaaaaggag atttggaggc cattcagtat
    11221 gcggcaggct gcgggtgcag cctgattgcc gcggcccacg gctcttccat ggaggagctg
    11281 gccgccaagc ccatgttcca ggaactgttt cgccagcaga ttttccgcag atttgtattt
    11341 ttgagcagaa gaaaaggacc tggtacggta gagagaattt tagaccataa aggatgtgaa
    11401 ctttatgttt cttaaggtcc tgggagcttt tctcgtcgtc ctttcctgca gcaggctggg
    11461 agtatatatg gcggcgagac tttcagaaag gcgggggctt ctgaagaaaa tcagagttat
    11521 ggtgatccat ctgagaggag aaattctcta tgccaacgcc ccgttgtatg agggatttca
    11581 gaaggccgga agacggacag gcggcaggga aggcctgctg tttgagaccg tttcagagca
    11641 gcttttgaaa gagcagggaa aggaattttt tgccatctgg caggaagccg taacgtcata
    11701 tttaccccag acgcctctta caaaggaaga aggggagcag cttctggcct tcggcgaaca
    11761 tctgggatat ctggatcggg aaatgcagga gagaacgctg tcgctgtatc tggaggaact
    11821 ggagcgggag atggaagagc tgaaccagga aattgcccag aaaggccgcc tctacaccag
    11881 tgcagggatt ctcacaggcc tgtttctggc agtaattttt atttaatcca gacaggagaa
    11941 tgacagcctg cgaaacagag ttcagggagg aaatggaatg ggagtcagtc tgatatttcg
    12001 aattgccgcg gtggggattc tggtatccgt catctgccag gtgttaaagc acagcggcag
    12061 ggaggagcag gcgttcctga caagcctggc aggcctggtt ttggtactgt tctggatggt
    12121 gccgtatatt tatgagctgt ttgagacaat gaaggagctg tttgcccttt agacagaaga
    12181 gaagaaagcg acgggaggaa taggacgatg acaggagagg agcttagacg cagaggattt
    12241 ctttattttg aaggaatcag ggaaggactt gagaactttg agtatgaaat tgccgcaatg
    12301 gaccacgcac aggcgcttct ccatttccgt aagctgagag aagagtatgg ggcggataac
    12361 agctttcttg atttttatct gttttcctta aaagaagagg agagggagaa agcagagtct
    12421 gctttaaatg aagaggagct ggaagctgtg agagcgtggg agaaaaaagc gggatttccg
    12481 agaggagatc aggtgatttt tcctatggat gacgcgcttt taagggcggc ggtagtcctg
    12541 aatgagacgg gaatgctgtt ttccaccatg tattttgcca gggaaggcgg aaaacaggga
    12601 gagaaagctg tccaggcaga gacctggtgg gggaatttta acggggagta cgtgagattt
    12661 taccgcaggt gagaggagga tatcacactc caaaatatag ggaagattgc acacagcgta
    12721 gtaagtccgc ttgaaaaaaa cataattcca aatataactg caatgataga acccgctttc
    12781 atcttttttt gaagaatgaa cacagatgga tgtttcggat caacatagat attataagtt
    12841 tctcccttcc tcatattttg cgtcaaaagc ttatatgaga tagtttgtgt tgtctgttct
    12901 tgatatatgg ttcc
//
LOCUS       DBMDUW010000068        12336 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_2636_length_12336_cov_3.046261, whole genome shotgun sequence.
ACCESSION   DBMDUW010000068 DBMDUW010000000
VERSION     DBMDUW010000068.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 12336)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 12336)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12336
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2636_length_12336_cov_3.046261"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..201)
                     /locus_tag="ACZPCR_10665"
     CDS             complement(<1..201)
                     /locus_tag="ACZPCR_10665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008721542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HIR1231363.1"
                     /translation="MKGETLDRRIRKTRRVIRQCLTELLKTKRIQDITVREISEKADI
                     NRGTFYLHYRDIFDLMEQIENEL"
     gene            457..1347
                     /locus_tag="ACZPCR_10670"
     CDS             457..1347
                     /locus_tag="ACZPCR_10670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008396175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HIR1231364.1"
                     /translation="MKRNKKHISSICLAAALLSLSVPGTVRAEESAGWVSDEAGWRYI
                     EADGTGAAPGWKLIDGSWYWFEDSGRMRTGWLLQGDTWYYLDDSGTMASGWRTIGGKS
                     YYFTESGAMKTGHVEQNGTVYSFHSDGSVDTAKKEKNTGGGAFEIGFYDEACQNLASN
                     LNELKLDSFDGDEDEDYYEDDKKDYDRDASYEISGKLTEIAAHRLAMAREKGYGNGKI
                     PEEGDLTDYLNSIQYNGGRRHMEVYIKNVDGAGEAEEKLLDIQEDAKKRQDRPDYYGG
                     MGIAHTEVNGSDYYMVIFMK"
     gene            1370..3574
                     /locus_tag="ACZPCR_10675"
     CDS             1370..3574
                     /locus_tag="ACZPCR_10675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HIR1231365.1"
                     /translation="MTMRTLIRTLKIKGMQLSGAPAGEKPKFSLPDFILEKSRAIEKL
                     FLVLVILSVIAAPFVEVNYDLTEYLPDTVQSKQGLDLMEEKFGYPGTARVMIEDVTLY
                     QAKLYKDELEAVDGVDQILWLDMGTDVYSSSSFIDSSDIADYYKDGSAVMDVTFVEGD
                     TSKKTSEAIDAMMEILGDKGYFTGPAVQNKSLEENVSREMNMILALGVLMIFLILCIT
                     TNSWFEPVLYLTIMGVAILINKGTNIFLGRISFLTDSVSAVLQLAVSMDYSIFLIHAY
                     TREKQKGIEQRQALRNAIDEALRSIFASSLTTIVGFIVLAFMKFSIGFDMGIVLAKGI
                     VVSLVTVVLFMPAMILRTMSLIERTAHRPFLPDFEGLSRKIYKIRWAVLIFVAVIIIP
                     AYTAQGMNSFLFGNESVGDSEGTKVYEDEQVINEKFGRSNLMIALVPNTSMVTEKAFS
                     DEVESLPYTKSVTSMAGTLPAGIPESFLPRSVTELLHKEDYARILIYVKSKGESPLAY
                     QCSDEIQAIMKRYYPEHSYLVGTTPSTQDIETTITKDYARVNAMSLIGVFLVVMFSFK
                     SLIIPLIIMIPIEVAVFINMAVPYIVGDTLIFMGYIIVSSIQLGATVDYAILTTSNYL
                     ECRREAGKEQAVIMALKRTIPAVLTSGSILTVAGYMVYKISSVAAIGDLGHLIGRGAW
                     MSMVLVLTLMPAFLALFDHILMDNEFQRLKKALSRRSRKKKVQEKEASGYET"
     gene            3564..5969
                     /locus_tag="ACZPCR_10680"
     CDS             3564..5969
                     /locus_tag="ACZPCR_10680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coiled-coil domain-containing protein"
                     /protein_id="HIR1231366.1"
                     /translation="MKHRMRIRISEKRMGKRLLASVMAAVTASTAIAVPASAAPPRVQ
                     VDETMYVNLDYYGSETEINVVKGCSTNGVTEYTDYGIYEKVENMTDSTEPSVGNGSVT
                     WKFPDKNQRFYYQCTLPKEEMELPWTFDISYKLNGVETEPKALNGASGLVEIHVKAVP
                     NQKAKAYFRNNMILTVAVPADMSKYYSIDAPGSQLQSVGSYSAAVFMALPGEEGDYTV
                     RLGSDSFESPGIVMMMVPGTASAFEHIADLKEAKDTWRENGDALYESYDAMLQAFESM
                     GTGVSTVQSGLGQLEQGRQILSGSRAAIESGSAQALDDLLSVTEQTSKLIPYLETAQN
                     AVTDINDNARAIYNTMEDMQDELDDLYSGLKSLQHSLERASDSIGAGITAAEQQAIAE
                     EIQKKAGQLEQILAALGQLGQGAGGSWQLALEDWEDLEEALSEADSFRYDRGSAKKPD
                     GQELSEKDSSEGAGKATASSAEEKGTQEEKREDESENSSVTAFSTDGEPVLLDPDRRG
                     PSGEPGSGGDNDADFEEWQEWQDEELEKYADQVEAGLQTVSGTSYGGDVGLLLQMVKE
                     LLGSSDETIAKAGALIQKINGLCSVISEAGEDTARVVKELRSCTDQLVNLLDDTRVMI
                     DTMDSYVPSMLDALGATEELMNRLAKAMGSTESVLRAVHNTLAAAGDSLDGGAKNTLA
                     GMQELLNHSLTAIESLKQVREASRNMKDTLDEQLDKFEEENNFLNLDPGEDLVSFTSG
                     KNPSPHSIQILLRTEEIDDEALSGDTADLEASAQADPGPLARIWNVLVKIVKAVVDIF
                     KNR"
     gene            6215..7534
                     /locus_tag="ACZPCR_10685"
     CDS             6215..7534
                     /locus_tag="ACZPCR_10685"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HIR1231367.1"
                     /translation="MGRGLDSFTVKEAEEYLNGIPKFTRKKHSIEELREILDETGLSL
                     DSVRLIHVAGTNGKGSVCAFLSSILREAGEPAAVFTSPHLVSVRERFVFDGKQVEEEE
                     FLAAFCRIQQLLPMMEERGLGHPSYFEYLFLMFAAMMQKRREYTAVLETGLGGRLDAT
                     NCVRRPQVCVITSVSLDHMEYLGTTVEQIAGEKAGIIKPGVPVFYDRSDARAAAVIES
                     QARRLKSPAFGVGEEASWQQTLEHGRLFLREGEKTLEIPFAAPYQVVNAMLAVRTAGY
                     LGISWQAVSEGVRKTVWPGRMEEIAPGVYLDGAHNEGGIRAFARAASQIPGKRKILLF
                     AAASDKEYPTMLRLLFETLRPDAAVLTRIAGSRGLEVETLRAAAEKEAREAGLSVPMT
                     VRPTAEEALLAALQDKGKDDTVFCAGSLYLAGEIEDVIRRNRYDKRR"
     gene            7518..7679
                     /locus_tag="ACZPCR_10690"
     CDS             7518..7679
                     /locus_tag="ACZPCR_10690"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231368.1"
                     /translation="MTKEDRTMIDFDEEISRFQPSLEVEDIGEAIVKSDLTDMSDIVM
                     EVLKHAKER"
     gene            7685..9118
                     /locus_tag="ACZPCR_10695"
     CDS             7685..9118
                     /locus_tag="ACZPCR_10695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIR1231369.1"
                     /translation="MDQLKKIRLASNGFYNLGLERAKIRDLTGAVEALKKCLMLNKYH
                     IDGRNLLGLIYYEMGEVSDALVQWVISMNFKEQDNRADYYLDQIQRKPERLDTVSQNV
                     KRYNQALAQAQAGDDDLAVLQLTKVVEVNPNFIKAHLLLAALYMSRGTYTKAGKSLLK
                     VLKIDKNNPKASWYMSIVKARTGRADVERRKLKNAFSHKKMQDDDVIIPPSYKENTGW
                     QSILNIVAGLALGAMVIFFLVMPTKIKALNNEHNQEILKYEEKINQRNEEIDSLNGQM
                     EQANSDKETAEQKLDEALNSNDSQVNQYAILVKMLQAYRNEDLTGAVTLYPGFNPSIF
                     TDETVLQIANGIKQDIETNGYQTLEDLAYTMWSAGRMDEALNYYNTCLTIRPQNPKVI
                     FSMGMIYRSKQDYAKAVELFTQVSTQYGDSEYAEKARNQLTELAPYVQTAPQQPAEPE
                     GEAQPEGGEPEAEPDHTDGGQEAEPQQ"
     gene            9351..9728
                     /locus_tag="ACZPCR_10700"
     CDS             9351..9728
                     /locus_tag="ACZPCR_10700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567355.1"
                     /note="This anti-anti-sigma factor, or anti-sigma factor
                     antagonist, belongs to a family that includes
                     characterized members SpoIIAA, RsbV, RsfA, and RsfB;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma factor antagonist"
                     /protein_id="HIR1231370.1"
                     /translation="MEQDFTYEASEQMLVIHLPREVDHHNCTALKNETDLILAENYVT
                     RMIFDFTDTQFMDSSGIGVLLNRYKQMRGSRGSVAYYGAGRQVKRILSIGGIAGIVQG
                     YDTKEAAIEGRLERREPCRRGWR"
     gene            9725..10162
                     /gene="spoIIAB"
                     /locus_tag="ACZPCR_10705"
     CDS             9725..10162
                     /gene="spoIIAB"
                     /locus_tag="ACZPCR_10705"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA];
                     GO_process: GO:0042174 - negative regulation of
                     sporulation resulting in formation of a cellular spore
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HIR1231371.1"
                     /translation="MKKNGRQTETMRMEIESRSENEEFARVAAAVFLSRLDPTVEEMD
                     DIKTAVSEAVTNAVIHGYGGGEGTIYIEIQVCGREARITIRDEGVGIADIGKAMEPMY
                     TSDPSGERSGMGFSFMEAFMDQVAVESEPGRGTAVIMTKTVGR"
     gene            10167..10901
                     /locus_tag="ACZPCR_10710"
     CDS             10167..10901
                     /locus_tag="ACZPCR_10710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008725298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HIR1231372.1"
                     /translation="MEGTERQDRTIQLISLAHQGDKEARDALVEENVGLIWSIVRRFA
                     GRGCETEDLFQIGSIGLMKAIDKFDTAFDVKFSTYAVPMIMGEIKRFLRDDGIIKVSR
                     SIREMGIRVSASRQKLSGTLGREPTLEELAEDVGASREEVAVSLEAGAQVESLYAPAA
                     GGEETNLSLLDRVGGENGGQEEALNRLVLRELLGTLEKKERDLIVRRYFYDQTQTKIA
                     EALGISQVQVSRMEKRILKKMREGFE"
     gene            11008..11148
                     /locus_tag="ACZPCR_10715"
                     /pseudo
     CDS             11008..11148
                     /locus_tag="ACZPCR_10715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006861934.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nuclease"
     gene            complement(11651..11980)
                     /locus_tag="ACZPCR_10720"
     CDS             complement(11651..11980)
                     /locus_tag="ACZPCR_10720"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231373.1"
                     /translation="MTNSTSITYRLKRKILAFTNKISCTLSKPHRKFTADMVYGILTS
                     RSCLLTDISSQLHETVHKANTVKRLSNHLSEGTPASAAASYLHTAKSIVPSEPVVLID
                     KSGIFPT"
BASE COUNT         3387 a         2609 c         3637 g         2703 t
ORIGIN      
        1 cagctcattt tcaatctgtt ccattaaatc gaagatatct ctgtagtgca ggtagaaggt
       61 tcccctgtta atatcggcct tttccgagat ttcccgcact gtaatatcct gaatccgctt
      121 tgtctttaaa agttcagtga gacactggcg gatcacccgc cgcgtttttc tgattctccg
      181 atcgagagtt tcccccttca taattaaaat ctcctttaaa tcgatgccta tttctggaaa
      241 tgatcaccag atatatgcat taatcaacat atatttataa tttgattatt aatgctctct
      301 gtgtggaaaa atgattattg tcaatcattt cgttcctgag tataatttat tataaatcat
      361 taatcaacac atgtcaatta atagaatctg tgtttgttaa caggatatat gttgaacaca
      421 ggacaaatat cactatagct tgaaaggaag atgtatatga agcgaaataa gaaacacata
      481 tccagtatct gcctggcagc ggccctgctc tctctttctg ttccaggaac agtcagggcg
      541 gaggagagcg ctggctgggt ttctgacgaa gcgggatgga ggtacataga ggcagacgga
      601 acaggcgcgg ccccgggctg gaagctgata gacggatcct ggtactggtt tgaggacagc
      661 ggacggatgc ggacgggatg gctccttcag ggcgatacct ggtattacct ggacgattcc
      721 ggcaccatgg cgtcaggatg gcggaccatc ggcggaaaaa gctactattt tacagagagc
      781 ggagccatga aaacaggcca cgtggagcag aatgggaccg tttattcctt ccacagcgac
      841 ggaagcgtgg acacggctaa aaaagaaaaa aatacaggcg gcggagcctt tgagatcggt
      901 ttttatgacg aggcctgcca gaatctggcg tccaacttaa acgagctgaa gctggacagt
      961 tttgacggcg atgaggacga agattattat gaggacgaca aaaaggatta cgacagggac
     1021 gccagctatg agatcagcgg aaagctgaca gagattgcgg cccaccgcct tgccatggcc
     1081 agagaaaaag ggtatggaaa cggaaagatc ccggaggaag gcgatctgac ggattactta
     1141 aacagcatcc agtataacgg cggccgccgc catatggagg tgtacatcaa gaatgtggac
     1201 ggagccggcg aggcggagga gaagcttctg gatatccagg aggacgcgaa gaagcggcag
     1261 gacagaccgg actactacgg cgggatggga attgcccaca cagaggtaaa cggaagcgat
     1321 tactacatgg tgatctttat gaaatagact ggcagggcag ggaattctga tgacgatgcg
     1381 aacattaata cggacattaa aaataaaagg aatgcagctt tcgggagcgc ctgcaggaga
     1441 aaagccgaag ttcagtcttc ctgattttat cctggaaaag agcagagcca ttgaaaagct
     1501 gtttctcgtt ctggtgattc tgtcggtgat tgcggctccc tttgtggagg tcaattacga
     1561 cctgacggag tacctgccgg acacagtgca gtcaaagcag gggctggatc tgatggagga
     1621 gaaattcggc tatccaggaa ccgccagggt gatgattgag gatgtgactc tctatcaggc
     1681 aaagctttac aaggatgagc tggaagctgt ggacggagtg gatcagattt tgtggctgga
     1741 tatggggaca gacgtctact cgtcttccag ctttatcgac agcagcgata ttgcagatta
     1801 ttataaagac gggtcggcgg tcatggacgt gacctttgtg gagggagata ccagcaagaa
     1861 aacctctgag gccattgacg cgatgatgga gattctgggg gataagggat actttacagg
     1921 tccggctgtg cagaacaagt ctctggaaga aaatgtcagc agggaaatga acatgattct
     1981 ggctctgggc gtcctgatga tttttctgat tctctgtatt accaccaatt cctggtttga
     2041 gccggtgctc tatctgacca tcatgggagt ggcgatcctt attaataagg gcaccaatat
     2101 ttttctgggc cggatttcct tcctgacgga cagcgtgtcg gctgtactgc agctggcagt
     2161 ttccatggat tactccattt tcctgattca cgcctacacc agggaaaaac agaagggaat
     2221 tgagcagagg caggcactca gaaacgctat cgacgaggcg ctccgctcca tttttgccag
     2281 cagcctgacg accatcgtgg gctttatcgt gctggctttt atgaagttca gcattgggtt
     2341 tgatatggga atcgtgctgg ccaagggaat tgtagtcagc ctggttactg tcgttttgtt
     2401 tatgcctgcc atgattcttc ggaccatgtc cctgatcgag cggacggccc accggccgtt
     2461 tctgcctgat ttcgaggggc tgagccggaa aatctataaa atacgctggg cagttctgat
     2521 ttttgtggca gtgattatca ttcccgccta cacggctcag ggcatgaatt ctttcctctt
     2581 tggaaacgag tcggtgggcg acagcgaggg aacgaaggtc tatgaggacg aacaggtgat
     2641 caatgagaag ttcggcagaa gcaatctgat gattgccctg gttcccaaca cctccatggt
     2701 gacggagaag gcgttttctg acgaggtgga aagcctcccc tatacgaagt ccgtgacttc
     2761 tatggcaggg acgcttccgg caggcattcc ggagagcttt ctgcccaggt cggtgacaga
     2821 gctgcttcac aaggaggatt atgccagaat cctgatttat gtaaaatcca agggggagag
     2881 tcccctggcc taccagtgct ctgacgagat tcaggcgatt atgaaacggt attatccgga
     2941 gcactcctat ctggtgggaa ccacgccctc cactcaggac atagagacta cgatcacaaa
     3001 agattatgcc agggtgaatg ccatgtccct gatcggcgtg ttcctggtag tcatgttcag
     3061 ctttaagtct ctgatcatac cgcttatcat tatgattccc atcgaggtgg cggtttttat
     3121 caatatggcc gtgccttaca ttgtggggga tactctgatt tttatgggct acattatcgt
     3181 aagctccatc cagctggggg ctaccgtcga ctatgcgatt ttgactacca gcaattacct
     3241 ggagtgccgc agggaggccg ggaaagagca ggcggtgatt atggcgttaa agagaactat
     3301 accggcggtg ctgacctccg gatccatcct gactgtggca ggctatatgg tttataagat
     3361 ttccagcgtg gcggccatcg gagatctggg acatctgatc ggcaggggag cctggatgag
     3421 catggttctg gtgcttacgc tgatgccggc ttttctggct ctgtttgatc acatcctgat
     3481 ggataatgag tttcagcggc tcaagaaagc cctgagcagg aggagcagaa aaaagaaggt
     3541 acaggaaaag gaggcttctg gctatgaaac atagaatgag aatcagaatc tcagaaaaaa
     3601 gaatggggaa acggcttctg gcctccgtca tggccgcggt aacggcgtcc acagccatag
     3661 ccgtgccggc gtctgcagcg cctcccagag tccaggtgga cgagaccatg tatgtcaatc
     3721 tcgattacta tggatccgag acagagatca acgtggtgaa gggctgcagc accaacggcg
     3781 tgacggagta tacagattac ggcatttatg agaaggtaga aaatatgacg gacagcacag
     3841 agccgtctgt ggggaacgga agcgttacct ggaagttccc tgacaagaat cagagatttt
     3901 attatcagtg tacccttccg aaggaagaga tggagcttcc ctggaccttc gacatttctt
     3961 ataagcttaa cggcgtggag acagagccaa aagccttaaa cggagcgtcc gggctggtag
     4021 aaatccatgt gaaggcagtc ccgaatcaaa aggccaaggc ctatttcaga aacaacatga
     4081 ttctgactgt ggcagttccg gctgatatga gcaagtatta cagcatcgac gcgccaggct
     4141 cccagcttca gtcagtggga agctattctg ccgccgtttt tatggcgctt ccgggagagg
     4201 agggcgatta cacggtgcgc cttggaagcg acagcttcga gagccccgga atcgtgatga
     4261 tgatggttcc aggaaccgcc agcgcttttg agcacattgc agatttaaag gaggccaaag
     4321 acacctggag agagaacggg gacgctctct atgaaagcta tgacgccatg ctgcaggcct
     4381 ttgaatccat gggcacaggc gtttccacgg ttcagagcgg tctggggcag cttgagcagg
     4441 gcagacagat tttatcaggc agcagagcgg cgattgagag cggctccgcc caggcccttg
     4501 acgatctgct gtctgtgaca gagcagacgt cgaagctgat tccttatctg gagacggccc
     4561 agaacgcggt gacggacatt aacgacaacg ccagggccat ctacaatacc atggaggata
     4621 tgcaggatga gctggacgat ctgtacagcg gattaaagtc tctgcagcat tccctggaac
     4681 gtgcttctga cagcatcgga gccggtatca cggctgccga gcagcaggcc atagcggagg
     4741 agatccagaa aaaggcaggg cagctggagc agattctggc ggccctggga cagctggggc
     4801 agggcgcagg cggaagctgg cagcttgcct tggaagactg ggaggatctg gaggaagccc
     4861 tttcagaggc agattccttc cgctatgaca gaggttccgc aaaaaagcct gacggacagg
     4921 aattgtcaga gaaagacagc tcagaaggcg ctggaaaggc cacggcaagc agtgcagagg
     4981 agaaagggac acaagaggaa aagagagaag acgagtcaga aaacagcagt gtgacggctt
     5041 tttccactga tggggagcct gtgcttttgg atccggacag gagagggcct tctggagagc
     5101 ctggatccgg cggggataat gacgcggact ttgaagaatg gcaggagtgg caggacgagg
     5161 agctggagaa gtacgcagac caggtggagg cgggacttca gactgtgtct ggaacctcct
     5221 atggcggaga cgtcggtctc ctgctccaga tggtgaaaga actgcttgga agctcagacg
     5281 agaccattgc gaaggccgga gccctgatcc agaaaatcaa cggactctgt tccgtcatct
     5341 ctgaggctgg ggaggatacg gccagggtgg tgaaggaact tcgaagctgc acggatcagc
     5401 tggtaaacct gctagacgac acaagagtga tgattgacac gatggacagc tatgtgccct
     5461 ccatgctgga tgctctggga gctacagagg agctgatgaa ccgtctggca aaagctatgg
     5521 gaagcacgga gagcgtgctg cgcgccgttc acaatactct ggcagctgcc ggagattctc
     5581 tggacggggg agccaaaaac accctggcag gaatgcagga gctgttaaac cacagcctga
     5641 cagccattga gagcttaaag caggtgagag aggccagccg gaatatgaag gatacgctgg
     5701 atgaacagct ggacaaattt gaggaggaaa acaatttcct gaatctggat ccaggcgaag
     5761 atctggtatc tttcacctcc gggaaaaatc cttcccccca cagcattcag atccttttaa
     5821 gaacggagga gatagacgac gaggcgttaa gcggagacac tgcagatctg gaggcctccg
     5881 cccaggcaga tccggggcct ctggccagga tctggaacgt gcttgtaaag attgtgaaag
     5941 cggttgtcga tatttttaaa aacaggtagc gccagtacgc gctgcctcag acgggaaaag
     6001 caggcgtttc aggcggcttt ctgtgaagtc tttcaggcgg atcggagggc cgctttgttt
     6061 ttcctgtcga gaaagcggaa aatttaccga aataaacttc ttgcataata gcgagcttat
     6121 attataatag agagatgaac aaaaagaaaa agcctgcgca gggacaggct gtctgcagac
     6181 agaggaagca gacagaagaa aggacaggaa agacatgggc agagggcttg acagcttcac
     6241 tgtgaaggag gcagaggaat acctgaacgg gattcctaaa tttaccagga agaagcattc
     6301 catagaagaa ctcagggaaa tattggacga gacaggactt tcccttgaca gcgtcaggct
     6361 gattcatgtg gccggaacga acggaaaggg ttctgtgtgc gcttttttgt cctcgattct
     6421 cagggaagcc ggggagcctg cggcagtgtt tacctctcct cacctggttt ctgtcagaga
     6481 gcggtttgtc tttgacggaa aacaggtgga agaggaggaa tttctcgcag cattttgccg
     6541 gatacagcag cttcttccca tgatggagga gagaggactt ggtcatccgt cttattttga
     6601 gtatttgttt ctgatgtttg ccgccatgat gcagaagaga agagagtaca cggcagtgct
     6661 ggagaccggg cttgggggga gactggatgc gaccaactgc gtccgccgtc cgcaggtatg
     6721 cgtgatcacc tctgtcagcc tggatcacat ggagtatctg ggaactacgg tggagcagat
     6781 tgcaggggag aaggccggca tcatcaagcc gggcgttccc gtattttatg acaggagcga
     6841 tgcacgggcc gccgctgtga ttgagagcca ggccaggcgt ttaaagagcc ctgcctttgg
     6901 ggtgggggag gaagcgtcct ggcagcagac tctggaacat gggcgcctgt ttttgagaga
     6961 gggagagaag accctggaaa tcccctttgc cgccccttac caagtggtaa acgccatgct
     7021 ggcagtccgg acggccgggt atctgggaat ttcctggcag gccgtttccg agggagtgag
     7081 aaagaccgtc tggccgggcc gtatggagga gattgctccc ggcgtctatt tagacggcgc
     7141 tcacaatgag ggcggaatcc gtgcgtttgc cagggctgcc tcccagattc caggaaagag
     7201 gaaaattctc ctgtttgccg cagcctcgga taaggagtat ccgacgatgc tgcgtctgct
     7261 gtttgagacg ctgcgccccg acgccgcggt actgacccgc attgccggca gcagagggct
     7321 tgaagtggag acgctccggg cggcggcaga aaaggaggcc agagaagccg gtctgtctgt
     7381 tccgatgaca gtcaggccga cagcggagga ggcgcttctt gccgcccttc aggataaagg
     7441 gaaggacgac acggtattct gcgcaggctc tctttacctg gcaggagaaa tagaagatgt
     7501 gataaggagg aaccgttatg acaaaagaag atagaaccat gattgacttt gacgaggaga
     7561 tcagccgttt ccagcccagc ctggaagtgg aggacatcgg agaagccatc gtaaagagcg
     7621 atttgaccga tatgtcagat attgtgatgg aagtacttaa acatgcgaaa gagcggtaaa
     7681 cgatatggat cagttaaaaa aaatccgtct ggcttccaac ggtttttata acctggggct
     7741 ggaacgggcc aagatacgcg acctgacggg ggcggtggag gcgctgaaaa agtgcctgat
     7801 gctgaataaa taccacattg acggaagaaa ccttctggga cttatctact atgagatggg
     7861 agaggtgtca gacgctctgg ttcagtgggt catcagcatg aatttcaagg agcaggacaa
     7921 ccgggccgac tattatctgg atcagattca gagaaagccg gagcggctgg atacagtaag
     7981 ccagaatgtc aagcggtaca accaggcgct ggcccaggcc caggccgggg acgatgatct
     8041 ggcagttctg cagctgacga aggtggtgga ggtaaacccg aactttatca aggcccacct
     8101 gctgctggca gcgctttata tgagccgcgg aacctacacg aaggcaggca aatcccttct
     8161 gaaggtattg aagattgaca agaataatcc caaggcatcc tggtacatgt ccattgtcaa
     8221 ggccaggaca ggccgggcgg atgtggagag aagaaagctt aaaaacgcct tttcccacaa
     8281 aaaaatgcag gacgacgatg tgattattcc gccttcctac aaggaaaata cgggatggca
     8341 gtccatctta aacattgtgg caggcctggc gctgggagcc atggtgattt tcttcctggt
     8401 tatgcccacg aagattaagg cgctgaataa tgagcacaat caggaaatcc tcaaatacga
     8461 ggagaagatt aatcagagaa acgaggaaat tgacagctta aacggacaga tggagcaggc
     8521 caacagcgat aaagagacgg cggagcagaa gctggacgaa gcgttaaaca gcaacgacag
     8581 ccaggtaaac cagtacgcga tccttgttaa aatgctgcag gcttaccgaa acgaggatct
     8641 gaccggggca gtcacactgt atccgggatt caatccgtcg atttttacgg acgagacggt
     8701 gcttcagatt gccaacggaa tcaagcagga catcgagacg aacggctacc agaccctgga
     8761 ggatctggcc tacaccatgt ggtcggccgg ccggatggac gaggcgttaa attattacaa
     8821 cacctgtctg accatccgcc cgcagaatcc gaaggtaatt ttcagcatgg gaatgattta
     8881 ccgttccaag caggattacg ccaaggcggt ggagctgttc acccaggtga gcacccagta
     8941 cggagattcc gagtatgcgg aaaaagccag aaatcagctg acagagctgg cgccttacgt
     9001 gcagacggcg ccccagcagc cggcagaacc agagggagaa gctcagccgg agggcgggga
     9061 accggaagca gagcctgatc atacagacgg cggacaggaa gcagagccgc agcagtaaga
     9121 cacataagaa tgaaaagaga cactacagaa gatggaagat tcttttgcag tgtctttttt
     9181 tgcgttaaaa atggaaaaaa cgccgggatt ccggctttcg ctgattcgta agctttttaa
     9241 caggacagga ataaaaaaag gactccgggg aatactttca taggacgcag tgagcagata
     9301 aacagaaaaa ggccggacaa aaaaactgga caggaaaagg aggaaaaggc atggaacagg
     9361 attttacata tgaggcgtcg gaacagatgc tggtgattca tcttcccaga gaggtagatc
     9421 accataactg tacggcgctg aaaaatgaga cggatctgat tttggcagaa aattatgtga
     9481 ccagaatgat ttttgacttt acggatacgc agtttatgga cagctcagga atcggggtgc
     9541 tgttaaaccg ctacaagcag atgaggggaa gcaggggaag cgtcgcctat tacggggcgg
     9601 gacgccaggt gaaacggatt ctgtctatcg gaggaatcgc gggaattgtg cagggatacg
     9661 atacgaagga ggcggccata gagggacgcc tggaaaggag agagccatgc agaaggggat
     9721 ggagatgaaa aaaaacggga gacagacaga gacaatgagg atggagattg agagccgctc
     9781 agaaaacgag gaatttgccc gggtggcggc ggcggtgttt ttaagccgcc tggatcctac
     9841 agtggaggag atggacgata taaagactgc ggtttcggaa gctgtcacca acgcagtcat
     9901 ccatggatat ggaggcgggg aagggaccat ttacatagaa attcaggtct gcggcaggga
     9961 ggcaaggatt acgatccggg acgaaggcgt tggaatcgca gacattggca aggccatgga
    10021 gcccatgtac acctccgatc cgtccggaga acggtccggc atgggattct cctttatgga
    10081 ggcctttatg gatcaggtgg ccgtggaatc agaacctggc cgcggaacag ccgtcatcat
    10141 gacaaagacg gtcggcaggt gagcgtatgg aaggaacaga gagacaggat agaacgatac
    10201 agctcatttc cctggcccac cagggagata aagaggccag agatgctctg gtagaggaaa
    10261 acgtaggcct gatctggagt attgtccgaa ggtttgcggg aaggggctgc gagacggagg
    10321 atctgttcca gatcggaagt atcggcctga tgaaggccat tgataaattt gacacagcct
    10381 ttgatgtgaa attttctacc tatgcagtcc ccatgattat gggcgagatc aagagatttc
    10441 tacgggacga cgggattatc aaggtaagcc gttccatcag ggagatggga atacgtgtca
    10501 gcgcgtccag gcagaagctg tcgggaacgc tgggcaggga gccgacgctg gaggagctgg
    10561 cagaggacgt gggggccagc cgcgaagagg tggccgtttc tctggaggcc ggggcccagg
    10621 tggaatctct gtatgccccg gcggcaggag gagaggagac aaatctgtct ctcctggaca
    10681 gagttggcgg cgaaaacggc ggacaggagg aggcgctgaa ccggcttgtc ctcagggaac
    10741 ttttgggaac ccttgaaaag aaggagcggg acctgattgt gagacgctat ttctatgacc
    10801 agacacagac aaaaattgca gaagccctgg ggatttccca ggttcaggtt tccaggatgg
    10861 agaagcggat tttaaagaaa atgcgggaag gctttgaata aaaacagaaa ttttctccat
    10921 actaataaga aatcgtttgg tgatgggcct gtgtctgccc aaaagctttg ggagtctagc
    10981 ttgaaaagaa ggagggatta tgccagtatg aacttacaag aggatagaag aaaatgggag
    11041 aaaggcatga caataagtca aaaaatagaa ctgaaacatc aggaggattt gcagcgcctt
    11101 agaggctttc gattacttga tgatgacttt ttgacaaaat gcttcgagag taagatgtgc
    11161 tggcaggcag ggtaagattt ttcaaagaga gtaaggaggg gattgcagct atgtgtaaga
    11221 ctatggaaga tatgagatag gaagcgttgc agaaatgtcc ggattactgc ttgatagggt
    11281 aaaagagttg gaagcgaata ggaatgtata agtcacattt tttatctgat acatagtaag
    11341 gcggagaaac tccgaacaaa tagcgaacat aaatggtaaa aattttggcc ggagaactga
    11401 aattggtttt ccggccgttt ttggaaaaat ttagaatggc agtaccggga atagaggcac
    11461 ttttatacag gtctgctttt tacaacgaaa atattcctcg atccgccatc tggaaaagta
    11521 ggttctggca atgcggatca catcatcctt tgaacggctc tctttgtttg cagccagcat
    11581 catgggatgt tccgtgatcc atagaccaga accagataaa tattcttccg ggaggcagtg
    11641 atctgaactt ttacgtggga aagataccac ttttatcaat gagaaccact ggttcagagg
    11701 gaacgatact ttttgcggtg tggagataag aagcagccgc agaagccggc gttccttccg
    11761 aaagatgatt ggaaagccgt tttacggtat tcgccttatg taccgtttca tgaagctggc
    11821 tggaaatatc agtgagcagg cagcttctgg atgtcagaat gccataaacc atatctgctg
    11881 tgaacttccg atgaggtttt gaaagtgtgc aggagatttt attagtaaaa gccaaaattt
    11941 ttcttttcaa acggtaggtg attgatgtag agttagtcat aaggaatctc ctttcttttt
    12001 gttcagtaag gtttttgttt gacggcttaa ttgcacatca aaaatgaata tgattcctta
    12061 tattttagct attttgaaag ctgaggacaa caaaacttaa tagatttgtc tcgtgtgggg
    12121 atgattatga ggaaaattaa ggtgttataa ataaattgac ttgaaataag aagagtgata
    12181 taataagtgt aaaataaaat atttggttga gttgtagatt tagagaggaa aacaatatga
    12241 aaaaattatt aatttttccc ccgggatggt caccagttgg gccatattta gctttaccga
    12301 ttttaaaatc atatcttaaa gaaaaagaaa atattg
//
LOCUS       DBMDUW010000069        11826 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_2751_length_11826_cov_2.702516, whole genome shotgun sequence.
ACCESSION   DBMDUW010000069 DBMDUW010000000
VERSION     DBMDUW010000069.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 11826)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 11826)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11826
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2751_length_11826_cov_2.702516"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            403..1512
                     /locus_tag="ACZPCR_10725"
     CDS             403..1512
                     /locus_tag="ACZPCR_10725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HIR1231374.1"
                     /translation="MRKNRKRIAVLSMAAVMALGMSVTALAKDDTKEVKGRLEIRFDG
                     EEPKAGDTMDIPGYTVSHYPEGVRHEVTDEYFDNEEDEFQRGTEPVICLEFESEDDYD
                     FDGFTKSDVKVSGMHTELKKVKKEDDDTTLIVYIEMRKISGDLEEPDETEWSGYTATW
                     GQVEDADKYEVKLYRNDNLVTTVTTPNDYYEFYSYMTKTGDYSFKVRAIHSGDNEKSE
                     WVESDELDLDSDEVYTTGGGTGTGWVQDAKGWWYRNPDGSSVVNAWLFVDNNWFHFNR
                     NGYMETDWQFIDNRWFYLNPVSDGTRGAMRTGWQQINGVWYYLNPVSDGTRGAMMTGY
                     QTIDGRTYYFDNSGAMWANRTAPNGRYLDGSGAMH"
     gene            1774..2745
                     /gene="argC"
                     /locus_tag="ACZPCR_10730"
     CDS             1774..2745
                     /gene="argC"
                     /locus_tag="ACZPCR_10730"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004461968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003942 -
                     N-acetyl-gamma-glutamyl-phosphate reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006526 - L-arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HIR1231375.1"
                     /translation="MRSITDRIGVNMEKPKVYIDGKEGTTGLQIYERLAGRTDIGLIL
                     AEEEKRKDLSERKKLINQADVVFLCLPDAAAAEAVALAENPDTRFIDASTAHRTAPGW
                     DYGIPELSQTHRERIAASRRVANPGCHATGFITSVYPLTARGIIPADYPLTAFSLTGY
                     SGGGKKMIAQYEGSDKPDSFLAPRMYGLTLKHKHLPEMQKICGLSEAPVFCPIVDDYY
                     KGMAVTVMLQNRLLPGCPSAQEIWEALAEWYEGQKVIRVHPFGYDGMISAASLSGHDN
                     LELIVNGHEEQTIVTALFDNLGKGASGAAVQNMNLMLGFEETRGLYL"
     gene            2776..3984
                     /gene="argJ"
                     /locus_tag="ACZPCR_10735"
     CDS             2776..3984
                     /gene="argJ"
                     /locus_tag="ACZPCR_10735"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004358 - L-glutamate N-acetyltransferase
                     activity, acting on acetyl-L-ornithine as donor [Evidence
                     IEA];
                     GO_process: GO:0006526 - L-arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HIR1231376.1"
                     /translation="MKIIEGGVCAAKGFKAGALHCGIRKSQTKKDLAMICSDCLCNAA
                     AVYTKNQVKAAPVLLTKEHLADGKAQAVIINSGNANACAPFGMEHARRQGMAAARALE
                     VEEENVVVASTGIIGQTLPVEAIEAHAAEMEMKYDNSLAAAEAIMTTDTKIKTFAVEF
                     EAGGTLCHMGGICKGSGMIHPNMGTMLCFITTDCAISANMMKKALLFYVDKTFNRVTV
                     DGDTSTNDMCVVMANGMAGNKEITEENESYDAYCEALHAVMKDLARKIAGDGEGASRL
                     ITCTVTGAEDEAKAEILAKSIASSSLTKAAMFGSDANWGRVLCAMGYSGASFDTKAVQ
                     IEFASAEGCISVCENGQGLDFDEALAKKILNQDEVEILVSLKEGCGTATCWGCDLTYD
                     YVRINGDYRS"
     gene            3981..4850
                     /gene="argB"
                     /locus_tag="ACZPCR_10740"
     CDS             3981..4850
                     /gene="argB"
                     /locus_tag="ACZPCR_10740"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004461965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003991 - acetylglutamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HIR1231377.1"
                     /translation="MMNLEPKQKAGILVEALPYIQEYTGKIVVVKYGGNAMVNEELKQ
                     AVIQDIVLLSLVGIKVVLVHGGGPEISDMLKKIGKETKFVKGLRYTDEETMDIVQMIL
                     CGKVNKNLVRLLEKEGGRGVGLSGMDGSLFQAVPLKDPDGTEYGYVGDITGVNEKIVL
                     DALDAGYIPVVSSVAAGADNDTCYNINADTAAEKLAVALKAKKLILLTDVCGLMSTPG
                     DASSLIPKLKVSEVPPLVKSGVISGGMIPKVDCCVEAIRQGVERANIQDGRIPHSLLI
                     EILSQDGVGTMFS"
     gene            4908..6086
                     /locus_tag="ACZPCR_10745"
     CDS             4908..6086
                     /locus_tag="ACZPCR_10745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetylornithine/succinylornithine family
                     transaminase"
                     /protein_id="HIR1231378.1"
                     /translation="MTLEEIKKQEEMYVMHTYNRFPIALERGKGAVLWDSEGRSYIDM
                     TSGIGVNSLGHQNKALLAAVNGQAEKLLHACNLYYTEPMVRAARSLICSTGMGKVFFA
                     NSGAEANEGMIKLARKYSFDKYGEGRSRIITLKQSFHGRTVTTLKATGQDKFHQYFFP
                     FTEGFDYVTPGNIEEMEEKLDDSVCAVMLELIQGEGGVLPLDQEFVKETEKICRKKDI
                     LLLIDEVQTGIGRTGTLFCYEQYGISPDVVSAAKGLGGGLPIGAVIASEKCGDVLGAG
                     THGTTFGGNPLCCAAADTVLSIINTPQFLNSVKEKGRYLKQAILNLGSEQIKEVSGMG
                     LILGIAVEPEKRAGLTAALMEKGVLVLTAGEDTIRLLPPLVITKEEIDRAVEAMKEVF
                     "
     gene            6089..7000
                     /gene="argF"
                     /locus_tag="ACZPCR_10750"
     CDS             6089..7000
                     /gene="argF"
                     /locus_tag="ACZPCR_10750"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - L-arginine biosynthetic process
                     via ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HIR1231379.1"
                     /translation="MNHLLKLLDCTSEEIVSILDLADQLKYEKKHGIAHRHLEGKSIG
                     LIFQKSSTRTRVSFETGIYQLGGQPLFLSARDLQIGRGEPVQDTARVLSRYLDGIMIR
                     TYEQREVEDLAKYGSIPVINGLTDFCHPCQVLADLMTIREKFGVLEGLKLCYIGDGNN
                     MANSLIVGGLKSGMNVSVAAPEGYRPAKEVMDFASDFEQFFLTDDPMKAAENADVIIT
                     DTWASMGQEDEKEVRMKAFQGYQVNDALMEAARPGAMVQHCLPAYRGQEITEKVFEAH
                     ADEIFEEAENRLHAQEAVMVMLMKDRQ"
     gene            7191..7457
                     /locus_tag="ACZPCR_10755"
     CDS             7191..7457
                     /locus_tag="ACZPCR_10755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HIR1231380.1"
                     /translation="MLEKRYLISASGNAQPPPISALMQAANLFGCNIYIVAGSFHFDV
                     KNYDELQRGLQPVRRVLVLCFDGADEEAAELRFHNLFGGFLKTA"
     gene            7660..8067
                     /locus_tag="ACZPCR_10760"
     CDS             7660..8067
                     /locus_tag="ACZPCR_10760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HIR1231381.1"
                     /translation="MRETVLLYNVQGDERKRKITKALLPLGFRLKTVAKEDYLKPVGF
                     LAGLKDMEDNGSVYEGEEFQDEMMLMAGFTSARVDTLLSALRKNGAGRINYKAVLTET
                     NKSWDSVHLFQEIKREHEYMTGGQTEAETSQEA"
     gene            8091..9203
                     /locus_tag="ACZPCR_10765"
     CDS             8091..9203
                     /locus_tag="ACZPCR_10765"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013271669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HIR1231382.1"
                     /translation="MKYRIMGKTGVQVSALGFGTMRLPLTDDGAVDEEEAVRILRAGI
                     DGGVNYVDTAYPYHGGFSETVVGKALQDGYREKVWLADKCPVWLLEEEGDFEKFLDEQ
                     LQKLQTDHIDFYLLHALNRKRFEEKVKKFSLIERMEEARKQGKIKFIGFSFHDTLDVF
                     EDILQYTDQWDFCQIQYNYINLDYQAGQKGLKMAADRGLGVVIMEPLLGGSLARLSEH
                     VAACLPEGKTPVEYAFDFLWDQPEVSLLLSGMGAMDQVKENLSYGDRCDVGMMTQKEK
                     QSLLRAKEIFDRMALVSCTACRYCMPCPFGLDIPASFAAWNMTALDEDDARKAYEALE
                     FQADACRGCGHCERVCPQHIPVSNVMKQMAEYFSKK"
     gene            9220..10464
                     /locus_tag="ACZPCR_10770"
     CDS             9220..10464
                     /locus_tag="ACZPCR_10770"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007882855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016628 - oxidoreductase activity, acting
                     on the CH-CH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BaiN/RdsA family NAD(P)/FAD-dependent
                     oxidoreductase"
                     /protein_id="HIR1231383.1"
                     /translation="MKQIAVIGGGAAGMMAALTAAKQGCRVTIYEKNEKLGKKIYITG
                     KGRCNVTNNCDMDVLFDSVVTNKRFLYSAFYSFTNQDVMELIEKAGCRLKTERGGRVF
                     PQSDKSSDIISALSRLLRDFGVEICLREPVKSLIIEEGVCRGLVLERQNKRIEADEVI
                     VATGGLSYPTTGSDGDGYRFAQAAGHQVAELSPALVPFTTEETTVKELQGLALKNIEI
                     SLHRGKKEIYHDFGEMLFTHFGVSGPVLLSASSYSVKELKKGPLTLEIDLKPALTAEQ
                     LDARILRDFDEAKNKQFKNSLNKLLPAKMIPVIVERSGIAPEKPVNEITKQERRSLVQ
                     AVKCFSLTVNGLRGFNEAIITQGGVQVKEVNPSTMESKKARNLYFAGEVLDLDAVTGG
                     FNLQIAWSTGYLAGLGAAECVE"
     gene            10491..11177
                     /gene="cmk"
                     /locus_tag="ACZPCR_10775"
     CDS             10491..11177
                     /gene="cmk"
                     /locus_tag="ACZPCR_10775"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0036431 - dCMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HIR1231384.1"
                     /translation="MPINIAIDGPAGAGKSTVARQLAKEMGYIYVDTGAMYRAMALCA
                     LRAGIQPADEAAVTEVCRKAEVSLEYRDGAQQILLNGENVTDLIRAEEVGNMASAISG
                     YLPVREKLVELQRELAARKDVVMDGRDIGTCVLPFADLKVYLTASSRVRAERRYKELL
                     EKGEERSLEEIERDIIERDNRDMSREISPLKQAEDAVLLDSSSMTLKEVLSELMELAE
                     DAGARGCCGC"
     gene            11263..>11826
                     /locus_tag="ACZPCR_10780"
     CDS             11263..>11826
                     /locus_tag="ACZPCR_10780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HIR1231385.1"
                     /translation="MEVRVAKTAGFCFGVKRAVDQVYEQIAHGKRPIYTYGPIIHNEE
                     VVRDLEEKGVRVLNSRDELATLTEGTVIIRSHGVGRNICELLEQNHITIVDATCPFVK
                     KIHKIVQEQGGNGRRVIIVGDENHPEVQGIKGWGKDDTLVIQSAEELENYELPEGEKL
                     CVVAQTTFNYNKFKDIVEKISKTRYDIL"
BASE COUNT         3374 a         2365 c         3447 g         2640 t
ORIGIN      
        1 ggtgcagttg gcagaccctc agtacgcctt ccgggcgtaa gcaggtaaca gccccttata
       61 ggggcagaac aagccaccgg ctaagccggt ggtcttgact atagagaacg agggcatcgc
      121 tcaatcatct aatttgatga ttttgcgaca ccctctttta tgatgcattt tgtgctgatt
      181 catataaatt gtcaaaaaaa cagttcaaat acagaaaaag tcataaaaat gtaagcaaaa
      241 agttaagaat agaaggaaaa attctgctat aataacgata acaaaaaaga atgtgcaaaa
      301 taattcaaac atctttgacg aactgtctct gatttggtat aatgaaccgt aagaatttaa
      361 agatgattct ggcaaaacga aggagaaaaa ggaggagaga atatgaggaa gaacaggaaa
      421 aggatcgcgg ttctttccat ggcagctgtg atggcgcttg gcatgtctgt caccgccctg
      481 gcaaaggacg atacgaagga agtaaaggga cgtctggaga ttcgttttga cggagaggag
      541 cctaaggctg gagataccat ggatattcca ggttacacag tcagccacta tccggaaggc
      601 gtcagacacg aagtgacgga tgagtatttc gacaacgagg aggatgaatt ccagaggggc
      661 acagagcctg ttatctgtct ggagttcgag tctgaggatg attatgactt cgacggtttt
      721 acaaagagcg atgtgaaagt cagcggtatg catacagagc tgaagaaggt taagaaggaa
      781 gacgatgata caactctgat agtttacatt gagatgcgga aaatttccgg tgatttggaa
      841 gaaccagacg agacagagtg gtccggatac acagctacct ggggccaggt ggaggatgcg
      901 gataagtacg aggtgaagct ttacagaaac gataacctgg ttacaaccgt gacgactccc
      961 aacgactatt acgagttcta ttcctatatg acaaagaccg gcgattacag ctttaaggta
     1021 agggctattc acagcggaga taatgaaaag agcgagtggg tagagtccga tgagctggat
     1081 cttgactctg atgaggtcta cacaactggc ggcggtacag gcacaggatg ggtacaggat
     1141 gccaagggct ggtggtacag aaatccagac ggaagttctg ttgtgaacgc atggctgttt
     1201 gtggacaata actggttcca cttcaacaga aacggttaca tggagacaga ctggcagttt
     1261 attgataacc gctggttcta tctgaatcca gtctctgacg gcacaagagg cgctatgagg
     1321 acaggatggc agcagattaa cggcgtatgg tactacttaa atccagtctc tgacggtacg
     1381 agaggcgcca tgatgacagg ctaccagacc attgacggaa ggacctatta ctttgacaac
     1441 agcggtgcta tgtgggcgaa ccgcacagct cctaatggac gctacctgga tggaagcgga
     1501 gcgatgcatt aaaaagatag ctgtatatta aaagagaatt taaagttttg gatatgccgg
     1561 gcaggtatct gcccggcata tccttttttg ctttacagga cgaggtttcc tctgaaacag
     1621 gaagacttta tagaaatggt tatttatgca atttaaataa agaaataccg caaaatagtg
     1681 cataaaaaga gtaaataata aatattccag aaatatattg catatttata aattaaatgt
     1741 tataattatg ccactccaca gggaggtggc ataatgagaa gcataacaga taggattgga
     1801 gtaaacatgg aaaaaccgaa ggtatatata gacgggaagg aaggaactac aggactgcag
     1861 atttatgagc gtctggctgg acgaacggat attgggctga ttttagctga agaggaaaaa
     1921 cgaaaagatc tttcagagcg aaaaaagctg ataaatcagg cggatgttgt atttttatgt
     1981 ctgccggatg cagcggcggc cgaggcagtg gcattggcag aaaatccaga tacgcggttt
     2041 attgacgctt ccaccgccca ccggactgcg ccgggatggg attacggaat accggagctt
     2101 tcccaaacgc atcgtgagag gattgctgct tcgcggaggg tggcgaaccc cggctgccac
     2161 gcaacaggat tcattacgtc tgtgtatcct ctgacagccc gggggattat tccggctgat
     2221 tatccattga cagcgttttc gctgaccgga tattccggcg gaggaaagaa gatgattgcc
     2281 cagtatgaag gttctgataa gccggacagt tttctggccc ccaggatgta tgggctgact
     2341 ttaaaacata aacatctgcc ggagatgcag aaaatctgcg gcctttctga agccccggta
     2401 ttctgtccta ttgtggatga ttattataag ggaatggccg ttactgtgat gctgcagaac
     2461 cgtctgctgc ccggctgccc gtcggcacag gagatctggg aggcgctggc agaatggtat
     2521 gaagggcaga aggtaatcag ggttcatccg tttggctatg acgggatgat ttcggcagct
     2581 tcattgtcag ggcacgacaa tctggagctg attgtaaatg gccacgagga gcagaccatt
     2641 gtgacggcgc tgttcgataa tctgggcaag ggagcgtcgg gagctgcggt acagaatatg
     2701 aatctgatgc ttggctttga ggagaccaga gggctgtatc tttaaaggaa tgagagaata
     2761 ggaggacgat ccagtatgaa aataatagag ggcggtgtct gcgccgcaaa aggatttaag
     2821 gcaggagctt tgcactgcgg cattcgcaaa tcgcagacaa agaaggatct ggcgatgata
     2881 tgttctgact gcctctgcaa tgcggctgcc gtatatacga aaaaccaggt aaaagccgcg
     2941 ccggtacttt taacgaaaga acatttggca gatggaaagg ctcaggcggt tattatcaat
     3001 tcaggaaacg ccaatgcatg cgcgcctttt ggaatggaac atgcgagaag gcaggggatg
     3061 gcggccgccc gcgccctgga agtggaggaa gaaaacgtag tagtcgcttc tactggaatt
     3121 attggccaga ctcttccggt ggaggccatt gaagcccatg cggcggaaat ggagatgaaa
     3181 tatgataatt ccctggcagc ggcagaagcc attatgacaa ctgatacgaa gataaaaacg
     3241 tttgccgtgg agtttgaagc cggaggcaca ctctgccata tgggaggaat ctgcaagggt
     3301 tccggaatga tccaccccaa tatgggaaca atgctctgct ttattacgac cgattgcgcg
     3361 atttctgcaa acatgatgaa aaaggcgctg ctgttttatg tggataagac gtttaaccgc
     3421 gttacagtag acggagatac ctccaccaac gatatgtgtg tggtaatggc aaacggcatg
     3481 gcgggaaata aagagatcac agaagaaaac gagtcttatg acgcgtactg cgaggcgctg
     3541 cacgcggtaa tgaaagacct ggcccggaaa attgcgggag acggagaagg agccagcagg
     3601 ctgataacct gtacggtaac aggagcggaa gacgaggcaa aggcagagat ccttgccaaa
     3661 tcgatcgcct cttcttccct gacaaaagcg gctatgtttg gatcggatgc caactggggg
     3721 cgcgttctct gcgccatggg ttattccggc gcttcgtttg acacgaaagc agttcagata
     3781 gagtttgcat cagcagaagg gtgcatttcc gtctgtgaga atgggcaggg actggatttt
     3841 gacgaggcgc tggctaagaa gattttgaac caggatgaag tggaaatcct ggtttccctg
     3901 aaagaaggct gcggtacggc aacctgctgg ggctgcgatt tgacttatga ctatgtaaga
     3961 ataaacggag attatcgctc atgatgaatt tagaaccaaa acagaaagcc ggaattctgg
     4021 tggaggcgct tccctatatc caggagtata ccggaaaaat tgtagtagta aaatatggcg
     4081 gaaacgctat ggtgaatgaa gagctgaagc aggcggtcat tcaggatatt gttctgctca
     4141 gcctggtagg tatcaaagtt gtcctggtcc atggaggagg cccggagatt tcggatatgc
     4201 tgaaaaaaat tggaaaagag acgaaatttg tcaaaggact ccgctataca gatgaagaga
     4261 cgatggacat tgttcagatg attctctgcg gtaaggtgaa taaaaacctg gtccggctgc
     4321 tggaaaaaga gggcggccgt ggagtggggc tcagcggcat ggacggcagc ctgtttcagg
     4381 ccgtgcctct gaaggatccg gacgggacag agtatggtta tgtaggggat attacaggag
     4441 tgaatgaaaa gattgtgctg gatgcgctgg atgcaggata catcccggtg gtgtcttcgg
     4501 tagccgcagg ggcagacaac gatacctgct acaatatcaa tgcagatacg gcggcagaaa
     4561 aactggcagt agccctgaaa gccaaaaaac tgattcttct gacagacgta tgcggcctga
     4621 tgagtactcc tggagacgct tcttccctaa ttcctaaatt gaaagtatcg gaggttccgc
     4681 ccctggtgaa atccggtgtg atttccggcg gtatgattcc caaggtggac tgctgcgtgg
     4741 aggcaatacg ccagggcgta gaacgtgcaa atattcagga tggccgtatc ccccattcgc
     4801 ttctcataga aattttgagc caggatggcg tgggaacgat gttttcataa aggatatagt
     4861 ttcatgaaaa atataaaaac tgctttagag aattgggagg aattgatatg acattggaag
     4921 agataaagaa acaggaggaa atgtatgtga tgcacacata caatcgtttt cccattgctc
     4981 tggaacgcgg aaagggagca gtactctggg acagcgaggg acgctcctat atagatatga
     5041 cttccggaat aggcgtcaac agcctggggc atcaaaataa ggcgcttctg gcggctgtaa
     5101 acggccaggc ggaaaagctg ctgcacgcct gcaacctcta ctacacagag ccgatggtac
     5161 gggcggccag gagcctgatc tgttccacag ggatgggaaa agtctttttt gccaactcag
     5221 gtgcggaggc taacgaagga atgattaagc tggccagaaa gtattcgttt gataagtacg
     5281 gggaaggccg cagccggatt ataactttaa agcagtcctt tcatgggcgg accgtaacta
     5341 cgctgaaagc gacaggccag gataagtttc atcagtattt tttccctttt acagaggggt
     5401 ttgactatgt gacgcctgga aacatagaag agatggaaga aaaattagac gattcagtct
     5461 gcgccgttat gctggaactg attcaggggg agggaggcgt gctgcctctg gatcaggaat
     5521 ttgtgaaaga aacagaaaaa atctgcagaa aaaaggacat tctccttctg attgacgagg
     5581 ttcagaccgg tatcggccgc accggcacgc tgttctgcta tgagcagtac ggaatttctc
     5641 cagacgtggt tagcgcggca aagggactgg gaggaggcct tcccatcggc gcagtcatag
     5701 cgtcagaaaa atgcggggat gtgctgggag caggaactca cggaacgaca tttggaggaa
     5761 atcccctttg ctgcgcggcg gcggacacgg ttctttccat catcaatacc ccgcaatttc
     5821 tcaattctgt aaaagaaaaa ggcagatatc tgaagcaggc gattttaaat cttggttctg
     5881 aacagataaa ggaggtcagc ggaatgggcc tgatacttgg catcgcagtg gaacctgaaa
     5941 aacgggccgg tctgactgcc gccctgatgg aaaaaggagt gctggttctg acggcaggag
     6001 aagatacgat tcgtctgctc ccgcctctgg taattacgaa agaagagata gacagagctg
     6061 tcgaggccat gaaggaggta ttttagatat gaatcattta ttaaaacttt tggactgtac
     6121 gtcagaggag attgtttcca ttctggacct ggcggatcag ctgaaatatg aaaaaaagca
     6181 tggaatcgcc catcgccatc tggaaggaaa atcaatcgga ctgattttcc agaaatcctc
     6241 aaccagaaca agggtttctt ttgaaactgg aatttatcag ctgggcggcc agccgctgtt
     6301 tctctctgcc agggatctgc agattggccg cggagagccg gtacaggata cggcccgcgt
     6361 tctgtcgcgg tatttagacg ggattatgat tcgtacctat gaacagagag aagtggagga
     6421 tctggcgaaa tacggttcga ttccagttat taacggcttg acagatttct gtcatccttg
     6481 ccaggtgctg gcggatctga tgactatccg ggaaaaattc ggcgttttag agggactgaa
     6541 gctttgctac attggagacg gaaacaatat ggcaaattct ctcattgtag gcggcttaaa
     6601 atccggcatg aatgtatctg tggctgcgcc ggaaggatat cgcccggcga aagaggtgat
     6661 ggattttgcc tctgattttg agcagttctt tctgacggac gatccgatga aagctgcaga
     6721 aaatgcggac gttattatta cagatacatg ggcatccatg ggacaggaag acgaaaagga
     6781 agttcgcatg aaggcgttcc agggatatca ggttaacgac gctttgatgg aggcagcccg
     6841 tcccggcgct atggtacagc actgcctgcc ggcatacaga ggccaggaga tcacagaaaa
     6901 ggtttttgaa gcgcatgcag atgaaatatt tgaagaggca gaaaaccgcc ttcacgcaca
     6961 ggaggccgtt atggtcatgc tgatgaaaga caggcagtaa cggcagtgcc gatccggtga
     7021 accagcagaa gcatccctca aaaagcaaga taattctgag taaagtacaa actgattcta
     7081 taaaaaaaga caattttgtc attatacaat attgacagaa ttttaaaata tgatatagta
     7141 aagggaagga acgtgcttgt gtgttgaatc atccataagg agggatgcgt atgctggaga
     7201 aacggtatct gatctccgca agcggaaatg cacagccgcc tccgatttcc gctttgatgc
     7261 aggcagctaa tttatttggc tgcaatattt acatagtagc aggttcgttt cattttgatg
     7321 tgaagaatta cgacgaactt cagagaggac ttcagccggt gagacgggtt ctcgtgcttt
     7381 gctttgacgg ggcggatgag gaagcggcgg aactgagatt ccacaattta ttcggaggat
     7441 ttttaaaaac agcatgaaaa caaaagatgg taatcagcga tagcagcctt ggagttgggg
     7501 aaattccgag gctgcttttc acagcccggg atttggcctt ccgggaattt cttacaggga
     7561 aaggttgtaa tttcagaacg gtttttttat aatattgatt gcaaagctgt gaataaacgg
     7621 ctgcggcaga caggaaaata gagggaaaag gagaacagta tgagagaaac tgtgctgtta
     7681 tataatgttc aaggcgacga gaggaaaagg aagatcacaa aagctctgct tccccttgga
     7741 ttccgcctga agacagtggc aaaggaagat tacttaaagc cggtaggctt tctggcaggc
     7801 cttaaagaca tggaagacaa cggctctgtt tatgagggag aagagtttca ggatgagatg
     7861 atgctgatgg ctggttttac ctctgccagg gttgatacgc ttctgagcgc tttgagaaag
     7921 aacggggcag ggcggattaa ttataaggcg gtgctgacag agacaaataa aagctgggat
     7981 tctgtccatt tattccagga aattaagaga gagcatgaat atatgacagg cggacagacg
     8041 gaagcagaaa cgtcacagga agcttaaaaa cgagaaggga agagaaaact atgaagtaca
     8101 gaataatggg gaaaacaggg gttcaggtat cagcgctggg atttggaacc atgcgtctgc
     8161 ctctgacaga tgatggggcg gtagatgaag aagaggcggt aagaattctc agggcgggaa
     8221 tcgacggcgg cgtgaattat gtggatacgg cgtatcccta tcatggcggc ttcagcgaga
     8281 cagtcgtggg aaaggctctg caggacggat accgggaaaa ggtatggctg gcagacaaat
     8341 gtcctgtctg gctgctggag gaggaaggag attttgagaa gtttttagac gagcagctcc
     8401 agaagctcca gaccgatcac attgattttt acctgctcca cgcactgaac cgcaagagat
     8461 tcgaggaaaa agtaaagaaa ttttctctca tagagcgtat ggaggaagcg agaaagcagg
     8521 gaaagattaa atttatcggc ttttctttcc atgatacgct ggacgtattt gaggatattc
     8581 ttcagtatac ggatcagtgg gacttctgcc agatccagta caactacatt aatctggact
     8641 atcaggcggg gcagaaggga cttaaaatgg cggcggacag ggggcttggc gtcgttatca
     8701 tggaacctct tctgggagga agccttgcca gactttcaga acatgtggct gcctgtctgc
     8761 ctgagggaaa aaccccggtg gagtatgcct ttgatttcct ctgggatcag ccggaggtga
     8821 gccttctgct cagcggaatg ggcgccatgg atcaggtgaa ggaaaatctt tcctacgggg
     8881 atcgctgcga cgtggggatg atgacacaga aggaaaagca gtctcttctg cgggcgaagg
     8941 aaatctttga ccggatggct ctcgtcagct gcacagcctg ccgctactgt atgccctgcc
     9001 ccttcggcct ggacattccg gcgtcttttg ccgcctggaa tatgacggct ctggacgagg
     9061 acgacgccag aaaggcttat gaggcgctgg agttccaggc ggacgcctgc cgtggctgcg
     9121 gacactgcga gagagtctgc ccgcagcata ttccagtcag caacgtgatg aagcagatgg
     9181 cggaatactt ttcaaaaaaa taaaaaagga acaaagaaaa tgaagcagat agcagtaatc
     9241 ggcggcggcg cagccggaat gatggcggcc cttactgccg cgaagcaggg ctgccgtgtt
     9301 acgatttatg agaaaaatga gaagctgggg aaaaaaattt atatcaccgg caagggacgc
     9361 tgcaatgtga ccaacaactg cgatatggat gtgctgttcg acagcgtagt caccaataaa
     9421 cggtttctgt acagcgcgtt ttacagcttt accaatcagg atgtgatgga gctgatagag
     9481 aaggccggat gccgtttgaa gacagagcgg ggaggacgcg tgtttcccca gtcggataaa
     9541 tcatctgaca ttatcagcgc tctttccagg cttctccggg actttggggt ggaaatctgc
     9601 ctgagagagc cggtaaaaag ccttatcatt gaggagggag tctgccgggg actggtgctg
     9661 gagcgtcaga ataaaagaat agaagccgac gaggtgattg tagctacagg cggtctgtct
     9721 tatcccacta ctggatccga tggagacggc tacagattcg cccaggcagc cggtcatcag
     9781 gtggcagaat taagtcccgc ccttgttccc tttaccacag aggagacaac ggtgaaggaa
     9841 ttgcagggct tggctcttaa aaatatagag atttctcttc acagaggaaa gaaggaaatt
     9901 tatcatgatt ttggggaaat gctgtttaca catttcggtg tcagcggacc agtcctttta
     9961 agcgccagca gctacagcgt caaagagctg aaaaaaggcc ccctgactct ggagatcgac
    10021 ttaaagccag cgcttaccgc agaacagctg gacgccagaa ttctcaggga ctttgacgag
    10081 gcaaaaaata agcagtttaa aaattctttg aataagcttc tgcccgctaa gatgatcccg
    10141 gttatcgtgg aacgcagcgg cattgcgcct gagaagccgg tcaacgagat tacaaagcag
    10201 gagcgaagaa gcctggtcca ggcggtgaaa tgcttttctc tgacggtcaa tggactccgg
    10261 ggatttaacg aggccattat cacacaggga ggcgtgcagg tgaaggaagt aaatccgtct
    10321 actatggagt ccaagaaggc ccggaatctg tactttgccg gtgaggtgct ggacctggac
    10381 gccgtgacgg gaggatttaa cctgcagatt gcctggtcta ctggttatct ggccggactt
    10441 ggcgcagctg aatgtgtgga atagaaaaaa tagatatgga ggaatagaca atgccgatta
    10501 atatagcgat tgacggaccg gcgggagcgg gaaaaagtac agttgccagg cagctggcta
    10561 aagagatggg gtatatttat gtagatacag gcgccatgta ccgggctatg gccctctgcg
    10621 cgctgcgcgc cgggatccag ccggctgacg aggcggctgt cacagaagtc tgccggaagg
    10681 cagaggtttc cctggaatac agggacggag cccagcagat tctgctgaac ggggagaatg
    10741 tgacggatct catccgggcg gaagaggtgg gaaacatggc ttccgctatc tccggctacc
    10801 ttcctgtgag agagaagctg gtggagcttc agcgagagct ggcagccaga aaggacgttg
    10861 tgatggacgg ccgcgacatc ggtacctgtg tgcttccttt tgccgatttg aaggtatatc
    10921 tgactgcttc cagcagggta cgggcagagc gcagatacaa ggagcttttg gaaaagggag
    10981 aagagcgcag tctggaggag attgagagag acattattga gcgggacaac cgggatatgt
    11041 caagagaaat atcgcccctg aagcaggcgg aggacgcagt gcttttagac tcctcgtcca
    11101 tgactctaaa ggaagttctt tctgaactga tggaactggc ggaggacgca ggcgccagag
    11161 gctgctgcgg ctgttaatcc ggcggggcgg agaaggcgct gcctagcaga agcggatgga
    11221 gagcatgctg gcagagcata tcaacaagga aggaaagaaa tcatggaagt gagagttgcg
    11281 aaaacggccg gcttctgctt cggcgtgaag cgcgcagttg atcaggttta cgagcagatt
    11341 gcccatggaa aacggccgat ctatacctac ggccctatta tccacaatga agaggtagtg
    11401 cgggatctgg aggaaaaggg agtcagggtc ttaaacagca gagacgagct ggcaaccctg
    11461 acggagggca cggtgattat ccggtcccac ggcgtgggga gaaatatctg cgaactgctg
    11521 gaacagaacc atattaccat tgtggacgct acctgcccct tcgtgaaaaa aattcataaa
    11581 attgtgcagg aacagggggg gaacggcaga agagtcatca ttgtaggaga cgagaaccac
    11641 ccggaagtac aggggattaa aggatggggc aaagacgaca ctctggtgat ccagtcggct
    11701 gaggagctgg aaaattatga gctgccagag ggagagaagc tctgcgtagt ggcgcagacg
    11761 acatttaatt acaataaatt taaagatata gttgaaaaaa tttctaaaac gcgttatgat
    11821 atactt
//
LOCUS       DBMDUW010000070        11783 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_2766_length_11783_cov_2.863294, whole genome shotgun sequence.
ACCESSION   DBMDUW010000070 DBMDUW010000000
VERSION     DBMDUW010000070.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 11783)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 11783)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11783
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2766_length_11783_cov_2.863294"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..210
                     /locus_tag="ACZPCR_10785"
     CDS             <1..210
                     /locus_tag="ACZPCR_10785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HIR1231386.1"
                     /translation="DGHRVDRHFVPGLIKNGPLLEESPDGSGGIMVGTKTTYVPGLYM
                     KEKAVGKYRSVVRSELDKRVRERFR"
     gene            207..656
                     /locus_tag="ACZPCR_10790"
     CDS             207..656
                     /locus_tag="ACZPCR_10790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail terminator family protein"
                     /protein_id="HIR1231387.1"
                     /translation="MKFTIQNLLSSLAGVLKTGYPDRPVYTSPNQQGTEFPCFFIFLM
                     PSSIEDGIGGRFLRDLGLDLVFVQQRNAANGNAEIQEVQEFLDQNLDKFLYYDESGSS
                     AWLHTYEREASVEDQELHYKFHVRPHVSAPIKENQMQGVEENHVKIK"
     gene            640..825
                     /locus_tag="ACZPCR_10795"
     CDS             640..825
                     /locus_tag="ACZPCR_10795"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231388.1"
                     /translation="MSKSNKEKKIQEIKRYPTEKLLKSKALSGYQPDFARVILKEPEY
                     SVEEAKAALEQALKPLL"
     gene            complement(832..1017)
                     /locus_tag="ACZPCR_10800"
     CDS             complement(832..1017)
                     /locus_tag="ACZPCR_10800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1231389.1"
                     /translation="MNLKKIRNEKSLSIRALSELADVPKRTIEDIERFDRCKVDTAIK
                     LADALQVTLDELCRSTE"
     gene            1502..2812
                     /locus_tag="ACZPCR_10805"
     CDS             1502..2812
                     /locus_tag="ACZPCR_10805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HIR1231390.1"
                     /translation="MNVKSQGSVAPNIGNRVVAIAEPLSWGPPNVIQEITPGQDVRPF
                     IGYDIASEQAMFLREMMKGSDTTAGPGKILLYRPKGSSGAKASAEIGALTVTAQYEGI
                     RGNDITIIIQEQVDADGTYDVETVIDGTVADEQSIQDLSQLKENAWVAFSGSGTTITE
                     TAGQALSSGKDPTVAAGDYADFLAALEPHQFDVLIYDGSDTATIQAFAAFVKRVSEHI
                     GQKCQAVMAGEAAAGCNSEYVIALKNGVKLEDGAVLTPQQTTWWAGGAEAGAMYYQSL
                     TYAQYPGALEASPKLTEQQASKAVQDGYLCFIDTFGSVKVCTDINTLTTFTPDKGEEF
                     SKNRVMRVLMQFCNDVYRQFSLYYIGKVDNNETGRSLLKSWIVGYLNEIQANNGIKNF
                     TAEDVTVSAGKTVDSVVITTAIQPVDAVEKIYMTVNVSANTESD"
     gene            2824..3291
                     /locus_tag="ACZPCR_10810"
     CDS             2824..3291
                     /locus_tag="ACZPCR_10810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HIR1231391.1"
                     /translation="MFLLERDALNGKEGKAFMTLNGRNIEMFSLKKFQSDAEFQESDF
                     KVVGTRLVQKKTTGVSLTGSMTIYYGTPHFLRILQEYLKTGKLPYFTLQVTNDDPSTS
                     VGTQTVAFYNVKLQKLPIAILDAEADFLEMEVSFSYTGIEVLNYFNDAPAQLG"
     gene            3305..3730
                     /locus_tag="ACZPCR_10815"
     CDS             3305..3730
                     /locus_tag="ACZPCR_10815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly chaperone"
                     /protein_id="HIR1231392.1"
                     /translation="MGNIKAFLLPPVMEETKSVIITKRAKGPDGKPVPFVIRVIDQET
                     NGKLLKRATKKTKLNGQIVQELDSDKYGKLLVQACVVSPDFQDSEICAYYKTMDPLEV
                     PGRMLTVGEYNRLVNAIKELNELVTEESELDELEDEAKN"
     gene            3883..5868
                     /locus_tag="ACZPCR_10820"
     CDS             3883..5868
                     /locus_tag="ACZPCR_10820"
                     /inference="COORDINATES: protein motif:HMM:NF040129.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HIR1231393.1"
                     /translation="MGKINETLTLTDQFSASFHTFIALGNQAVQTTQMLDKNLTRAMG
                     KSAGAVIGSIRELGGQLEKQNQDMLKIIQNQKRHQTEVERTNRSAKQLLSTFRNIVAA
                     TGATMLAKSFLSFSDTQTQIIARLGLMNDGLQDTMQLNEMIYQSAQRSRASYTSTADA
                     IAKMGLNAGNAFSSNQELIAFMESVNKQFAIGGGSVAAMEGAMVQLTQAMASGALRGE
                     ELNSILDAAPGIARNIEQYMGWASGSIKQYAEDGMVTAEVVKNAMLASADEINEQFQS
                     MPMTLSQAMTQLQNEVQHSLQGAASEWSDFINSADGQRVLRQMINLFSLLAQIGVDAL
                     SAIGQGAVWVAENLDFIIPILAAIGAALAFVKIQSVMAAGFSVAGALASAGAWMLAHL
                     PILLLVMVLAAAMIAAQQFGIGMQEVGGWVGQVFGMIYAVGYNVFATLWNVIAAFAEF
                     FANVWNDPLGATVRLFAEVFDSILGMVETVAGAIDALLGSDLSGAVAGFRDKVSGWVD
                     ENFGENAVQIKRMSTLDVYGTSKQWGQYGSNLGSKLDNLSLNLEDLAGGLGGLGNGSF
                     SVLSGDSMDIGKVGSVGNVKNVEGSVNLADEDLKLYRDMAERRYMNQVELKTLAPNIS
                     VTLPSGSSKNLTAEDVADRIRRMLIEQMASSTAVSHG"
     gene            5878..6579
                     /locus_tag="ACZPCR_10825"
     CDS             5878..6579
                     /locus_tag="ACZPCR_10825"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231394.1"
                     /translation="MGRIENGCSIYLKFGSRKVKIPVNPEELEIQYPTDHKTYTVLGQ
                     GEIVVPRKPSLRTVSWESFFPAGDEPYVNSKAKEPEDYEQYFSEALKKKTKCRLIISR
                     SGLYDTNMRCIVSEFKTIDKGGEPGDMYYSIELTEYRDYSSETLVIASTGQGNTEAAA
                     SSESERPVETPSLRVGASVTANGKYWYDSYGSKPFGTANNLSTTVTRIVPGNPYPIHI
                     GSYGWLQESQIQITG"
     gene            6591..7574
                     /locus_tag="ACZPCR_10830"
     CDS             6591..7574
                     /locus_tag="ACZPCR_10830"
                     /inference="COORDINATES: protein motif:HMM:NF048266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdQ/YqbQ family protein"
                     /protein_id="HIR1231395.1"
                     /translation="MSLRIQSDAGITEYADLTTEAELVTQRLDSPAKFTFTCIQQGVC
                     GIEAGNHVSFAVGGVPLFKGYVFTIEQNQDGEITCTAYDQLRYLKANASYVFEAMTLG
                     QMIQQIAADFNLTCGTLEDTGYAFPCLIKENESCLDIIFDALAETIYRTGRIFNFYDD
                     NGALTLREAKNMYVNTLIGDSSLMTEYTYKKDIDSDTYNRVKLVKANSETGKADVYLH
                     EDTETIKKWGLLQYYDEVDENMNEAQIDQLCQTYLAYYNRVLQTVSFEAVGVKEIRAG
                     TIVPVRIGAVNDLQISRLLLTEKVTHKFEADTHTMNIEVKDFGQLGGMNLV"
     gene            7567..7890
                     /locus_tag="ACZPCR_10835"
     CDS             7567..7890
                     /locus_tag="ACZPCR_10835"
                     /inference="COORDINATES: protein motif:HMM:NF022300.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HIR1231396.1"
                     /translation="MSEVELLGAFQLAIQQSIKAMKLADMATGTVLSGAPLSVQLDVS
                     VPPIPEQALLLTDAVKPKSVTAPVQGGEGGTVTMIIQEALKAGDKVLMLRVMKGQKYV
                     ILSRL"
     gene            7898..8299
                     /locus_tag="ACZPCR_10840"
     CDS             7898..8299
                     /locus_tag="ACZPCR_10840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HIR1231397.1"
                     /translation="MATLPEHVGLSSELAYTELPTNTFLIDWTSKQIAGMDAGLPAMR
                     QAVEIILANERYRWQIYNSNFGCELEDLPGEESDYIVSELPRRIREAFSADKRILSAD
                     NFVFSDLGGGRMAVTFDVITVFGTFSEEVKV"
     gene            8296..9450
                     /locus_tag="ACZPCR_10845"
     CDS             8296..9450
                     /locus_tag="ACZPCR_10845"
                     /inference="COORDINATES: protein motif:HMM:NF016736.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HIR1231398.1"
                     /translation="MIDFSGYTREQIQKEMLSQVPKTIDTRQGSLIQTALGPVAWYLE
                     GIYMLLAKIQQNAYAETAVGQALDYICEERGVFRKQAVAAVRQGTFDRTIPEGSAFKT
                     INGANSVIFISGQQIAVVSRKEKTQYVYQLTCTTPGIIGNSYTGAILPITAIPGLTSA
                     SIGEIVISGAEEEEDDSLRARFMETFEAASFGGNIASYRNHILAIEGVGAVQVYPVWK
                     GGGTVLCSILNSDLKPAETELIKRVQELVCPPEEGGLGPSENGYGIAPIGAQVTIGTA
                     EELILNLSCEIQFSAGAEASTYQSQVEEKIQEYIQSVCEEWGAPLKTRKVEYPVAIYI
                     ARIIAAILAIPEAVNVSNVMLNGSRKDLILTETAELQQIPKLGEVVINGS"
     gene            9440..10342
                     /locus_tag="ACZPCR_10850"
     CDS             9440..10342
                     /locus_tag="ACZPCR_10850"
                     /inference="COORDINATES: protein motif:HMM:NF021583.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative phage tail protein"
                     /protein_id="HIR1231399.1"
                     /translation="MAVDLMEILPEYFRPILEFQEIMEAEGEAAEEVERTADRLSDNC
                     FIQTCDEATLAYYERLLQISNIGATLEERRRILLLQWNMESLYTLPKLKEFLASAVGE
                     DNYEIKCFYNEYLVKIWISSQTAVMLRNLYNSIFRMTPAHIILEVYGRYLGKYEVPIK
                     YENKIRFFSEFYPRFNLAVLKLDGTWKLDGGRKLNGYDSNETLDFYPVAMSVSVPVAV
                     PVQTELSCRYQMTAMENVKAEAALNICTEAAENVRMEQRLTCQSGAEVSVLQAEAFMY
                     KKNMLNGSWKLNGSRKLDGGRYNL"
     gene            10422..10763
                     /locus_tag="ACZPCR_10855"
     CDS             10422..10763
                     /locus_tag="ACZPCR_10855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231400.1"
                     /translation="MAHAGDGSLPKIAKMVWGDGGVDDQGVPKETTGTEVGLYNKLLE
                     KEIEGYSYVNEEKTTCRYKATLEKGELTGKEISEMGLLDADGDLIAYRTFTRKGKDED
                     IPQEYDMDEIF"
     gene            10776..11204
                     /locus_tag="ACZPCR_10860"
     CDS             10776..11204
                     /locus_tag="ACZPCR_10860"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231401.1"
                     /translation="MGNFEIQDPPIFQTEITKWSRETDADGDEMGRDMEKVFNNTIYN
                     KAMIERERHVTEVLLTAVDWQEENGLYIQTISVPGTEEDMDPVLYSALADEADAEARK
                     AYKKAFGIISSGSGIVRAGTATFKVDKKPATDCMVGLRGV"
     gene            11208..>11783
                     /locus_tag="ACZPCR_10865"
     CDS             11208..>11783
                     /locus_tag="ACZPCR_10865"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231402.1"
                     /translation="MGKIWMPGGGGGGASSDDCTLMRAAMPKGLTAVTADSDDEALEG
                     TLDTETTLSDSQALSGQTYLKFNPQTKLFEKRTGGMANKGAWTGSVAMNGSITIPAGF
                     HNGSGNVKGPVITNRGNYGGTGNSRGNDTSGKRMWVKVPGGYYNENAQVFLNWSDICS
                     MAGLTADKLKKDVSIMGITGTYVGEIPETYYI"
BASE COUNT         3323 a         2264 c         3360 g         2836 t
ORIGIN      
        1 gatggacatc gggtagacag gcattttgtt ccagggctga ttaagaacgg tcctcttctg
       61 gaggaaagcc cagacggaag cggcggtatc atggtaggaa ccaaaaccac ctacgtccct
      121 ggcctttata tgaaagagaa ggcagtcgga aagtaccgct ctgtggtgcg ttctgagctg
      181 gataaacgag tgagggagcg gtttcgatga agtttaccat acaaaattta ctcagcagcc
      241 tggccggtgt tttgaagacg gggtatccgg accggccagt gtacacaagc ccgaatcagc
      301 aggggacaga attcccgtgt ttttttattt tcctgatgcc gtccagtatt gaagatggaa
      361 tagggggccg ttttctgcgg gatttggggt tggatcttgt gtttgtgcag cagagaaatg
      421 ctgccaatgg aaatgcagaa atccaggagg tacaggaatt tttagaccag aacctggaca
      481 aatttttgta ttacgatgaa agcggaagct ctgcctggct tcacacatat gagagagagg
      541 cgtcagtgga agatcaggaa cttcactata aattccatgt ccggccgcat gtgtcggcgc
      601 cgataaagga aaatcaaatg cagggggtgg aggagaatca tgtcaaaatc aaataaagaa
      661 aagaagatac aggaaatcaa gcggtatccg acggagaagc tgctgaaaag caaagcttta
      721 tccggatatc agccagattt tgccagggtg attttgaaag aaccggaata cagcgtagaa
      781 gaggcaaaag cggccctgga gcaggcgctt aagcctcttc tgtaatcaat gctattctgt
      841 ggaacggcac agctcgtcaa gcgtgacctg aagcgcatcg gccagcttga tagcggtgtc
      901 taccttacag cggtcaaacc gttcaatgtc ctcaatagta cgcttgggaa catcagccag
      961 ttcagacagg gcgcgaatgc ttaatgattt ttcattcctg atttttttta agttcatggc
     1021 ataacctcct gttaagtgaa taatagaatc agaccaacta caatgataac aagccagatg
     1081 gcagaggcaa gtaacgagag aatgctgatc actgtttttt tcatattgct ttaaaaatgg
     1141 tgatatgata tattttaggt ggggaggttt ccctccccgg gtaattattg gaggctttca
     1201 acaatcattt tgatgactgc taaaagtgtt ccaatttcta aagcgagctg gataagtgct
     1261 gataccactt ttttcagctc ctttattttt tccaccattt ttctcttcac ctcctttcga
     1321 tagtttaatt ataccacgtt ataacgtgga aaccaagagg aaaagaggaa aatattgaaa
     1381 aaaattcaga gcgtccttct tcggaggggc gttcttttta tacaaaaatt atgaaagaga
     1441 ggtaaacaca atggcaggag gcatatggac aagccagaat aaacagctcc ccggtgtata
     1501 catgaatgta aaatcacagg gcagcgtggc cccgaatatc gggaatcgcg tggtggcaat
     1561 tgcggaacca ctatcctggg ggccgccaaa tgtgattcag gaaatcacgc cggggcagga
     1621 tgtgcgcccg tttatcggct atgatatcgc atcagagcag gccatgtttt tgcgtgaaat
     1681 gatgaaaggc agcgatacga ctgcgggtcc gggaaagatt ttgctttatc gtccgaaagg
     1741 aagcagtgga gcgaaagcat ctgcggagat tggagcttta actgtaacgg cacagtatga
     1801 aggaatcagg ggaaacgata ttaccattat cattcaggag caggtggacg cagatggaac
     1861 ttatgatgtg gagactgtca ttgatggaac tgtggcagat gaacagagca ttcaggattt
     1921 atcccagctg aaagaaaatg cctgggtagc tttttcaggt tccggaacga ctatcacgga
     1981 gacggcagga caggcgcttt cttctggaaa ggatccgacg gtggcggcag gagattatgc
     2041 ggactttctg gctgcccttg agccgcacca gtttgatgtc ttgatttatg acggatccga
     2101 tactgccacg atccaggcct ttgctgcatt cgtgaaacga gtatcagaac atatcgggca
     2161 gaaatgccag gctgtgatgg ctggagaagc tgcagcaggg tgcaacagcg agtatgtcat
     2221 tgcattgaaa aacggcgtaa agctggagga tggcgcggtt ctcacgccgc agcagaccac
     2281 ctggtgggcg ggaggagcag aggcgggggc gatgtattat cagtctttga cctatgccca
     2341 gtatccggga gctttagaag ccagtcccaa gctgacggag cagcaggcat ccaaggcagt
     2401 acaggacgga tatctatgct ttattgatac ctttggaagt gtgaaggtct gcacagacat
     2461 taacacactg acaaccttta cgcctgacaa aggagaggaa ttttccaaaa acagggtaat
     2521 gcgggtcttg atgcagttct gcaatgatgt ataccggcag ttcagcctgt attacatcgg
     2581 aaaggtagat aataacgaga caggccgcag cctgttaaaa agttggattg ttggctattt
     2641 aaacgaaata caggcgaaca acggaattaa gaattttaca gcggaggatg tgacggtatc
     2701 tgctgggaaa acagtagact ccgtagttat tacgacggcg attcagcctg tagatgcggt
     2761 agagaaaatc tatatgaccg tcaatgtatc tgcaaacact gagagtgatt aaggaggaag
     2821 agcatgtttt tgctggaacg ggatgccctc aacggaaaag agggtaaggc ctttatgacc
     2881 ttaaatggaa gaaatataga gatgttcagc ctgaagaaat ttcagtctga cgcggagttc
     2941 caggaatctg attttaaggt ggttgggaca agactggtac agaaaaaaac gacaggagtt
     3001 tccctgactg gttcgatgac gatttactat ggaactcctc atttcctgag aattcttcag
     3061 gagtatttaa aaacaggaaa gcttccatac tttacgcttc aggtcaccaa tgacgacccg
     3121 tctacaagcg tggggacgca gacggttgca ttttataatg taaagcttca gaagctgcca
     3181 atcgctattc tggatgcgga agcggatttt ctcgagatgg aagtcagctt ttcttacaca
     3241 ggaattgaag tgctgaatta ttttaatgat gccccggctc agctgggata agaaggagga
     3301 tataatggga aatattaaag cgtttttact gccgccggta atggaggaaa caaagtctgt
     3361 gattatcacg aaaagagcga agggaccgga cgggaagccg gttccttttg tgatccgtgt
     3421 cattgatcag gagaccaatg ggaaattgtt aaagcgggcc acaaagaaaa caaaactgaa
     3481 tggacagatc gtccaggaac tggattccga caaatatgga aagcttctgg tgcaggcctg
     3541 tgtggtgagt ccggattttc aggattccga gatttgcgcc tattataaga caatggatcc
     3601 tttggaggtt cctggacgta tgctgacggt tggagaatat aaccgcctgg tgaatgcaat
     3661 caaggaattg aatgaactgg tgacagaaga gagcgagctg gatgagctgg aggatgaggc
     3721 aaaaaactag cttccgggaa tacgctggat tcaaggctgt gccagtatat gctttgcaat
     3781 cacggcgtta ttccctctga ggtcttgaag ataccgctga aagaaaaact ttttatgtgg
     3841 gagctgctgc aaaaagagat gaaggaggtt aaaagaaaat aaatgggaaa aattaatgag
     3901 actttgacct taaccgatca gttttccgcc tcctttcata cgtttattgc tttaggaaat
     3961 caggcagtac agacaacgca gatgttagac aaaaatctga ccagagcaat gggaaagtcg
     4021 gcaggagctg tcatcggatc aatccgggaa ctgggaggcc agttagaaaa acagaatcag
     4081 gatatgctta aaatcatcca aaatcagaag cggcatcaga cagaagtgga gagaacgaac
     4141 cgttcggcaa aacagctttt gtccaccttc agaaacattg tggccgcaac tggagcgacg
     4201 atgttagcta agtcttttct gagtttttct gatacgcaga cacagatcat agcaagactg
     4261 ggtttgatga atgacggcct gcaggatacg atgcagctga atgaaatgat ttatcagtct
     4321 gctcagcgtt cccgggcttc ttacacgtct acggcggatg cgattgcaaa gatgggcctg
     4381 aatgcaggaa atgcgtttag ctccaatcag gagctgatcg cttttatgga gtctgtcaat
     4441 aagcagttcg ccattggcgg aggaagtgtg gcggctatgg agggagcgat ggtgcagctg
     4501 acgcaggcaa tggcctctgg agcgctgcgg ggagaagagc ttaattccat tttagacgcc
     4561 gcgcctggaa tcgcccgcaa catcgagcag tacatgggat gggcttccgg ctctattaag
     4621 cagtatgcgg aggatgggat ggtaacggcg gaagttgtca aaaatgcgat gcttgcatca
     4681 gcggacgaaa tcaatgaaca atttcaaagt atgcccatga cactgtccca ggctatgaca
     4741 cagctccaga acgaagtcca gcacagcctt cagggtgctg catcagaatg gagtgacttt
     4801 attaactctg cagatgggca gagagtcctg cgccagatga tcaacctgtt ttctctgctt
     4861 gcccagatag gtgttgacgc tttgtcagcc atcgggcagg gggctgtttg ggtggcagag
     4921 aatctggact ttatcatccc gattctggct gcgattggag cggctttggc tttcgtaaag
     4981 attcaatcgg taatggctgc tggatttagt gttgccggag cgctggcgtc agcgggagca
     5041 tggatgcttg cgcatctgcc gattttgctt cttgtaatgg tactggcagc ggctatgatt
     5101 gcagcccagc agttcggcat cgggatgcag gaggttggcg gatgggtcgg ccaggttttc
     5161 ggaatgattt atgcagtggg atacaatgtc ttcgctactc tctggaatgt gattgcagct
     5221 tttgcagaat tttttgcaaa tgtatggaat gatcctctgg gtgctaccgt ccggctgttt
     5281 gctgaagtgt tcgattctat cttggggatg gtggaaacgg tagctggagc gattgacgcg
     5341 cttttgggaa gtgatttatc aggagcagtg gccggttttc gcgacaaagt gtcaggctgg
     5401 gtagatgaaa acttcggaga aaatgccgtt cagattaagc gcatgtcaac gcttgatgta
     5461 tacggaacct caaaacagtg gggacagtat ggttctaatc ttggctcgaa gctggataat
     5521 ctcagcctga atttggagga tctggcaggt ggcctgggag gactgggaaa tggaagtttt
     5581 tctgttctgt ctggggactc aatggatatt ggaaaggttg gaagtgttgg aaacgtaaaa
     5641 aatgtggaag gcagcgtcaa tcttgcggac gaggatttga aactttaccg agatatggct
     5701 gagcggcggt atatgaatca ggttgagctg aaaaccctgg ctcctaatat ttctgttacg
     5761 cttccgtctg gttccagcaa aaatctgact gccgaggatg tggcggaccg gattcggcgg
     5821 atgctgattg agcagatggc cagcagcaca gcagtatcgc atggatagga gggggcaatg
     5881 ggaagaattg aaaacggctg ctcgatttat ttgaaatttg gcagcaggaa agtgaagatt
     5941 ccggtcaatc cggaagaact ggagattcag tatccaaccg atcataaaac atatactgtg
     6001 ctggggcagg gagaaatcgt agttcccagg aagccgtcgt taaggactgt ttcctgggaa
     6061 tcttttttcc cagcaggcga cgagccatat gtgaatagca aagctaagga accggaagat
     6121 tatgaacagt atttttcaga ggctttgaag aaaaagacga aatgccggtt gattatttcc
     6181 cgttccggtc tctatgacac gaatatgcgc tgcattgtat cggagtttaa aacgatagat
     6241 aaaggcggcg agccggggga tatgtattat tccatcgaat tgacggagta tcgggattat
     6301 tcttcggaga cactggtgat tgcctccact gggcagggaa acacagaagc agcagcctct
     6361 tctgagtcgg aacgtcctgt ggaaacgccc agcctgcggg taggagcttc tgtgacagcc
     6421 aatgggaagt actggtatga cagctatgga agcaagcctt ttggaactgc gaataatctg
     6481 agcacgacgg ttacaaggat tgttcctgga aatccctatc cgattcacat tggttcctat
     6541 ggatggcttc aggagagcca gattcagatt acggggtgac aaaaatggat atgtctttga
     6601 gaattcaatc ggatgccgga ataacagaat atgcagattt aacgacagag gcagagctgg
     6661 tgacacagcg gctggacagt ccggctaaat ttacgtttac ctgtatccag cagggagtat
     6721 gcggtataga ggcaggaaat catgtgtcct ttgctgtggg cggtgtgcct ttatttaaag
     6781 gttatgtttt tactattgag cagaatcagg atggggaaat tacctgcact gcttatgatc
     6841 agctccgata cctgaaggct aatgcaagct atgtatttga ggctatgact ttggggcaga
     6901 tgatccagca gatagccgct gattttaact taacctgcgg caccctggag gataccggct
     6961 atgcgtttcc ctgtctgatt aaggaaaacg agagctgcct ggatattatt tttgacgccc
     7021 tggcagaaac gatttaccgg acagggagga tttttaactt ttacgatgac aatggcgctt
     7081 tgacgctgcg ggaagctaaa aacatgtatg tcaatacgct catcggagac agcagtctga
     7141 tgacggagta tacctataaa aaagatatcg actcagacac ctataaccgg gtgaaactgg
     7201 tcaaagccaa cagtgaaacc ggaaaggctg acgtgtacct gcacgaggat acggaaacca
     7261 ttaagaagtg ggggcttttg cagtattacg atgaagtaga tgaaaatatg aatgaagcac
     7321 agattgatca gctgtgccag acttatctgg cctactataa ccgagtgctg cagacagtga
     7381 gctttgaggc ggtaggggta aaggaaatcc gcgccggtac gattgtacca gtacggatag
     7441 gcgcagtcaa tgatcttcag atttcgcggc ttcttctgac tgaaaaagtg acgcacaagt
     7501 ttgaagcgga tacccataca atgaacattg aggtgaaaga ttttggacag ttgggaggga
     7561 tgaatcttgt ctgaggtaga gttattaggt gcatttcagc tggcgattca gcaaagtatc
     7621 aaggcgatga agctggcaga catggcaaca ggaaccgtct tgtcaggggc accgttatcg
     7681 gtacagctgg acgtgtctgt gcctcccatt ccggaacagg cccttctgct gacggatgca
     7741 gtaaaaccga aaagtgtgac ggcgccagtg cagggaggag aaggcggaac agtaacaatg
     7801 ataattcagg aagcgttaaa agcaggagat aaggtactga tgctccgggt tatgaaaggg
     7861 cagaagtatg tgatcttgtc gagattgtga gggacatatg gcaacattac cagaacatgt
     7921 gggtctgtcg tcggaactgg cctatacgga acttccaacc aatacgtttc tgattgactg
     7981 gacgtcgaaa cagattgcag gaatggatgc agggcttccg gcgatgcggc aggcggtgga
     8041 gattattctt gccaatgaaa gatatcgctg gcagatttat aacagcaatt ttggctgtga
     8101 actggaggat ttgcctgggg aagaatctga ctacattgtg agcgagcttc ccaggcggat
     8161 tcgagaagca ttttccgcag ataagcgtat tctgtcagca gacaatttcg tattttcaga
     8221 tctgggaggc ggcaggatgg cggttacctt tgatgtgatc actgtatttg ggacgttttc
     8281 agaggaggtt aaggtgtgat tgattttagt ggatatacca gagagcagat ccagaaggag
     8341 atgctttccc aggttccaaa gaccatcgat accaggcagg gaagtctgat tcagacggcc
     8401 ctggggccgg ttgcctggta tctggaagga atttacatgc tgctcgcgaa aatacagcag
     8461 aatgcctacg ctgagactgc ggtgggacag gctctggact atatctgcga ggagcgggga
     8521 gtttttcgaa aacaggcggt tgcagccgtc cgccagggaa cttttgacag gacgattccg
     8581 gaaggaagtg cgtttaagac cataaacggc gccaattcag tcatttttat cagcggacag
     8641 cagatagctg tagtgagcag gaaggaaaag acacagtatg tctatcagct gacctgtaca
     8701 acgccaggga tcattggaaa cagctataca ggagcgattt taccaattac agcgattcct
     8761 ggactgactt ctgcttccat cggagaaatt gtaatatccg gagcggagga ggaagaggac
     8821 gactctctgc gtgcccgttt tatggaaacc tttgaagcgg cgtcctttgg aggaaatatt
     8881 gcttcctacc gaaatcatat tctggccatt gagggggtgg gagccgtcca ggtttaccct
     8941 gtctggaaag gtggcggcac agttttatgc agcattttaa acagtgattt aaagccagcg
     9001 gagacagaac ttatcaagcg agttcaagaa ctggtctgcc cgccggagga gggcggcttg
     9061 gggccgtcag aaaatggcta tgggattgct cctatcggtg ctcaggtaac aattggaacg
     9121 gcagaggagc tgattcttaa tctttcctgt gaaattcagt tttcggcggg agcagaagct
     9181 tctacatacc agtcccaggt ggaggaaaag attcaggaat acatacaaag cgtgtgtgag
     9241 gaatgggggg cgccgctaaa aaccagaaag gtagagtatc cggtagcaat ttacattgcc
     9301 cgtattattg cggcaatcct tgccattccc gaggcggtca atgtatccaa tgtgatgctc
     9361 aacggctcta gaaaggattt gattttgacg gaaacggcag aactgcagca gattccgaag
     9421 ctgggggagg tggtgatcaa tggcagttga tttgatggaa attttgcctg aatatttcag
     9481 accgatcttg gaattccagg agattatgga agcggaagga gaagcggcag aggaagtgga
     9541 gagaaccgcg gacaggcttt ccgataactg ctttattcag acctgcgatg aggcgacact
     9601 ggcttattac gagcgtttac tgcagatttc caacatagga gcgaccttgg aggaacggcg
     9661 caggattctc cttctgcagt ggaatatgga atccctttat acacttccga agctgaaaga
     9721 atttctggca tcagcagtag gagaggacaa ttatgaaatt aagtgttttt acaatgaata
     9781 tctggtaaaa atatggattt ccagtcaaac tgcagtaatg cttagaaatt tgtacaattc
     9841 gatttttcgg atgacgccgg cgcatattat cctggaagtg tatggccgat atctgggaaa
     9901 atatgaagtg cctatcaaat atgagaacaa gatccggttt ttctctgagt tttatcccag
     9961 gtttaatctg gctgttttaa aactggatgg aacctggaag ctggacggcg gccgaaaatt
    10021 aaacggatac gacagtaacg agacgctgga tttttatccg gtggctatga gcgtaagcgt
    10081 gccagttgca gttccagttc agacagagct gtcctgcaga tatcaaatga cagcaatgga
    10141 gaatgtgaaa gcagaagctg cgctgaacat atgcacggaa gcggcagaga atgtgagaat
    10201 ggaacagagg ctgacctgtc agtcaggggc agaggtttct gtactgcagg cagaagcttt
    10261 tatgtataaa aagaacatgc tgaacggctc ctggaagctg aatggcagcc ggaagctgga
    10321 cggcggtcgg tataatttgt aaacggttaa ggccgggaaa ggataaaaat atggcaagca
    10381 ataaaggtgt aattacagta acaggcagga aaaagctttg tatggcacac gcaggagacg
    10441 gcagtctccc taaaatcgcc aagatggtgt ggggagatgg cggcgtggat gatcaggggg
    10501 ttcctaagga gactaccggc acggaggtag gactttataa taaactcctg gaaaaagaga
    10561 tagagggtta cagttatgtg aatgaagaga agaccacctg caggtataaa gccactttgg
    10621 aaaaagggga attgacagga aaagaaattt cagagatggg acttctggac gctgacggtg
    10681 atctgattgc ctatcgtacc tttacaagga aagggaagga tgaggatatc ccccaggagt
    10741 acgatatgga tgagattttt taatggaggt acagcatggg aaattttgaa attcaggatc
    10801 cgccaatatt tcagacggag attacaaaat ggagccggga aacggatgcg gatggcgatg
    10861 aaatgggccg ggatatggaa aaggtattta ataataccat atataacaaa gctatgatag
    10921 agcgggaaag gcacgtgacg gaagtgctgc ttacggcggt tgactggcag gaggaaaatg
    10981 gtctgtacat acagacgata tccgtaccag gaactgagga agatatggat ccggtactgt
    11041 acagtgcttt ggccgatgaa gcggatgcgg aagccaggaa agcttataaa aaagcttttg
    11101 gaattatttc atctggcagc ggaatcgttc gggccgggac ggccacattt aaagttgata
    11161 aaaaaccagc tacagactgt atggtgggct tgagaggagt gtaagctatg ggaaagattt
    11221 ggatgccagg cggaggaggc ggtggagctt ccagtgatga ttgtacgctg atgagagctg
    11281 ctatgccgaa aggtttgacg gcagtgacgg cagactccga tgatgaggct ttggagggaa
    11341 ctctggatac agagacaaca ttgtcagatt cgcaggccct gagcggccag acatacctga
    11401 agtttaaccc tcagacgaag ctctttgaga agcggactgg aggcatggcc aataagggag
    11461 cctggaccgg cagtgtagcc atgaatggtt ccattacgat cccagcaggc tttcataacg
    11521 gctccggtaa tgtgaagggg ccggtcatta caaaccgagg aaactacggc ggcacaggaa
    11581 acagccgtgg aaatgataca tccggcaaac ggatgtgggt gaaagtaccg ggcggatatt
    11641 acaacgaaaa tgcgcaggtg ttcctaaact ggagcgacat ctgttcgatg gcagggctaa
    11701 cggcggacaa gcttaaaaag gatgtgtcga taatgggtat tacaggaacc tatgtaggag
    11761 aaattcctga gacctattat att
//
LOCUS       DBMDUW010000071        11026 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_2953_length_11026_cov_3.748833, whole genome shotgun sequence.
ACCESSION   DBMDUW010000071 DBMDUW010000000
VERSION     DBMDUW010000071.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 11026)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 11026)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11026
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2953_length_11026_cov_3.748833"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(75..1616)
                     /gene="guaA"
                     /locus_tag="ACZPCR_10870"
     CDS             complement(75..1616)
                     /gene="guaA"
                     /locus_tag="ACZPCR_10870"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002596053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HIR1231403.1"
                     /translation="MEKEMIIVLDFGGQYNQLIARRVRECNVYCEVHPYSMPIEKIKE
                     MNPKGIIFTGGPNSVYGDDSPRCSKEIFELGIPVLGICYGAQLMAHLLDGKVATAPVS
                     EYGKTEVEVDTASKLFTGVSPKTICWMSHTDYIEKAPEGFAVTAHTPVCPVAAMEYPE
                     KKWYSVQWHPEVMHTQEGTKMLSNFVYNVCGCKGDWKMDAFVESSIEAIREKVGSGRV
                     LCALSGGVDSSVAAVMMAKAVGKQLTCVFVDHGLLRKNEGDEVEAVFGPNGPYDLNFV
                     RVNAQERFYAKLAGETDPETKRKIIGEEFIRVFEEEAKKIGAVDFLVQGTIYPDVIES
                     GLGKSAVIKSHHNVGGLPEHVDFKEIIEPLRMLFKDEVRKAGLELGIPEHLVFRQPFP
                     GPGLGVRIIGDITPEKVKIVQDADAIYREEIDKAGIAKNLGQYFAALTNMRSVGCMGD
                     GRTYDYAIALRAVLTSDFMTAEAAEIPWEVLSKVTSRIVNEVKGVNRVMYDCTGKPPA
                     TIEFE"
     assembly_gap    1671..1680
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(1721..2200)
                     /locus_tag="ACZPCR_10875"
     CDS             complement(1721..2200)
                     /locus_tag="ACZPCR_10875"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF012792.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1231404.1"
                     /translation="MRQAEETQIPEFIQVIQERIDWMESRGMKQWNDEEYLDFYSEEY
                     FRAQARAGHLFFLIKEGKAAGVTTLLEEDDRWEDGSREYFYVHHLASRTGIPGAGSAF
                     LELIEDYARKQGKRGIRLDCQLGNEPLNRFYERNGYVTVGEPFTAGGYTGIRKVLEF"
     gene            complement(2336..5188)
                     /gene="uvrA"
                     /locus_tag="ACZPCR_10880"
     CDS             complement(2336..5188)
                     /gene="uvrA"
                     /locus_tag="ACZPCR_10880"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007862772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HIR1231405.1"
                     /translation="MAKQYIKIRGANEHNLKNISVDIPRNELVVLTGLSGSGKSSLAF
                     DTIYAEGQRRYMESLSSYARQFLGQMEKPDVESIEGLSPAISIDQKSTNRNPRSTVGT
                     VTEIYDYMRLLYARIGIPHCPRCGREIHRQTIDQMVDQIMAMPERTKIQLLAPVVRGR
                     KGEHVKVLEHARKGGYVRVRIDGSLYELSEEIKLDKNIKHNIEIVVDRLVVKPGIEKR
                     LTDSIETVMELTGGLMTVDIPDQESMNFSQNFACPDCGISVDEVEPRSFSFNNPFGAC
                     PDCYGLGYKMEFDEDLLIPDKSLSISQGAIVGMGWQSCTDKGSFTRAILDALVEEYHF
                     SLDTPFRDYPKEIHDVLIHGTGGKVLKVRYKGQRGEGVYDVAFEGLIQNMNRKYRETF
                     SDAMKAEYETYMRITPCPVCKGQRLKKEALAVTVGGKNIFEATNMSIVKYREFIDGLN
                     LTVMQETIGAPILKEIRARVSFLIDVGLDYLTLARATGTLSGGEAQRIRLATQIGSGL
                     VGVAYILDEPSIGLHQKDNDKLLKTLLHLRDLGNTVLVVEHDEDTMLAADCIVDIGPG
                     AGEHGGNVVAVGTAKQIMKCKDSITGAYLSGRIKIPVPTERRKPTGWITVKGAAENNL
                     KNIDVSFPLGVMTCVTGVSGSGKSSLVNEILYKALAKKLNRARTIPGKHKEIQGTEQL
                     DKIIAIDQSPIGRTPRSNPATYTGAFDLIRDLFASTPDAKAKGYNKGRFSFNKKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCEVCGGKRYNRETLEVKYKGKSIYDVLNMTVEEALH
                     FFENVPSIYRKIETLNDVGLSYVRLGQPSTQLSGGEAQRIKLATELSKRGTGKTIYIL
                     DEPTTGLHFADVHKLIEILRRLSDGGNTVVVIEHNLDVIKTADYLIDIGPNGGDKGGT
                     VIAQGTPEQVAENPVSYTGQYVKKYLNLGAEDTKQE"
     gene            complement(5624..7525)
                     /gene="ftsH"
                     /locus_tag="ACZPCR_10885"
     CDS             complement(5624..7525)
                     /gene="ftsH"
                     /locus_tag="ACZPCR_10885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019161321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HIR1231406.1"
                     /translation="MEKRDSDQNKPPKRSFLYYYGIVMLVLLLLNIFVFPSVMDKTVE
                     GRYDEFLTSLNAGEVDEVYVTTNDEVMYTLKGDSRGAVHKTGLMPGDNITERLAGTDA
                     RFSSEIQTQASPLLDFLLTWIAPFVILVLIGQLMSRAMMKRMGGPNAMTFGKSNAKIY
                     AESETGKTFADVAGQEEAKEALKEIVDFLHNPQKYTDIGATLPKGALLVGPPGTGKTL
                     LAKAVAGEAHVPFFSISGSEFVEMFVGMGAAKVRDLFKQANEKAPCIVFIDEIDTIGK
                     KRDGNIGGNDEREQTLNQLLTEMDGFDGQKGVVILAATNRPDSLDKALLRPGRFDRRI
                     PVELPDMRGREAILKVSARGVKMDETVDYNEIARATSGASGADLANIVNEAALRAVRM
                     GRRMVSQQDLEESVEVVIAGYQRKDAEVSVNEKKIVSYHEIGHALVAAMQSHSAPVHK
                     ITIIPRTSGALGYTMQIEEDQRFLMSRDEAFNKIVTLTGGRAAEELIFHSITTGASND
                     IEQATRIARAMVTRFGMSEQFGMVALETVSNQYLGGDASLACSEHTAMRIDEEVIDTV
                     RQAHDKACQILKENEEKLHELAAYLLEKETITGEEFMEILKKENLETAGADAEEKVER
                     DHTEIQDNV"
     gene            7741..8208
                     /locus_tag="ACZPCR_10890"
     CDS             7741..8208
                     /locus_tag="ACZPCR_10890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003502153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HIR1231407.1"
                     /translation="MDDEKLRTAGTHFLEFAFSFLTFAKCQYQSANHIKINSLPFFTL
                     SILADQKDENYTMSDLADKLQITKQQLSKLINDLEDKALVERIHDTANRRRVYIRISP
                     CGLEAMERLKETMLETTIAALHIYNEEELETLNSCLESLTPLMEKFHLKECGE"
     gene            8461..10092
                     /locus_tag="ACZPCR_10895"
     CDS             8461..10092
                     /locus_tag="ACZPCR_10895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003502152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucan-binding protein"
                     /protein_id="HIR1231408.1"
                     /translation="MRKQTKLVAVLSAAALLAVGASMTSFAGWEKDEDGIWHYYDSDD
                     EMVTDEWRKDGSKWFYLDEDGNMLTEAWVDDEYYVGADGAMVKNDWVKTTADEDVSDP
                     EDDGDNWYYFGSNGKKVEDDSKKINGKTYYFNEDGEMRYGWYEDNGDVFYLGGEDEGW
                     RAESQWLWLALPDEDEVDRNGVNFCDDDSACSVHCDEEGWYYFGSNGKMYKEAAKKKV
                     NGKYYFFNAHGQMLYEWINNQKYRVSSSSDLVSGNGYTAPGAASSSNGILDDNANYQG
                     SSQIWNMQYSNVVEDGSRANGWYEIDGSADTGEDGDTDWYYFDDGEAERADAGKDFVT
                     VDGDGADVFRAKIKINGKYFCFNEMGQMQTGLQYIGADHAFYFFDENGYMQTGKETNV
                     EDDDDSYNFYFITKNGKNGQGQMGEKDNYLYFGGKRLEADDDYRIYFFDGKYYLVNNK
                     GKIQDSKSKKYDVENGNGMTEAKFTFRNDGSISKVEIEGTNGNYSEVPAATWQADATY
                     PEIALYDGYFTYDTDHQNALVWLTEAQYNALGRNQ"
     gene            complement(10535..10651)
                     /locus_tag="ACZPCR_10900"
     CDS             complement(10535..10651)
                     /locus_tag="ACZPCR_10900"
                     /inference="COORDINATES: protein motif:HMM:NF028245.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HIR1231409.1"
                     /translation="MTAYETIMVIIGILSLLIAFAGFIIAFIAFLDKRNKRK"
BASE COUNT         2765 a         2940 c         2308 g         3003 t
ORIGIN      
        1 tgtcatttga ttgtcaacgg acataggaag agccaagaaa gcccgtaaaa taggcatttc
       61 ttggctctaa tatattattc aaactcaatc gttgccggcg gctttccggt acaatcgtac
      121 ataacgcggt taactccctt cacctcgttg acgattctgc tggttacctt gctcagtacc
      181 tcccacggga tttctgctgc ctctgcagtc atgaaatcgc tggtgagtac ggcgcgcaga
      241 gcgatggcat agtcgtatgt tcttccatct cccatgcagc cgacggatct catatttgtc
      301 aatgcggcaa agtactggcc aagattcttg gcaatgcctg ccttgtcaat ctcctcgcgg
      361 tagattgcat ctgcatcctg tacaatcttt accttctccg gcgtgatatc gccgataatt
      421 cttacgccga ggcctggccc tgggaacggc tggcggaata ccagatgctc cggaatgcca
      481 agctccagtc ctgcctttct cacctcatcc ttgaacagca tacggagagg ctcgataatt
      541 tccttgaaat ctacgtgctc tggaagtcct cctacgttgt gatgggactt gataacagca
      601 gattttccaa gtcccgactc gatcacatcc gggtaaatag ttccctgtac taagaagtca
      661 acggctccga tcttcttagc ctcttcctca aatacgcgga taaactcctc gccgataatt
      721 tttctctttg tctccggatc agtctctcct gccagctttg catagaaacg ctcctgagcg
      781 tttacacgga caaaattcag atcatacggg ccgtttggtc caaatactgc ctcaacctcg
      841 tctccttcgt tctttcttaa aagaccatgg tcaacgaata cgcaggtcag ctgctttcca
      901 actgcctttg ccatcataac tgccgctaca gaagagtcta ctccgccgga taaggcgcag
      961 agcacacgtc cggaacctac cttctcacgg attgcctcaa tagagctctc cacgaaagcg
     1021 tccatcttcc agtctccctt gcagccgcat acattatata caaagttgga cagcatcttt
     1081 gtaccttcct gtgtgtgcat aacctccgga tgccactgta cagaatacca cttcttctcc
     1141 ggatattcca tggcagctac cgggcatacg ggagtatgag ctgtcacagc aaagccctcc
     1201 ggcgccttct caatataatc tgtatggctc atccagcaga tcgtctttgg ggaaacgcct
     1261 gtgaacagct tggacgctgt gtccacctct acctctgtct ttccgtactc gctgacagga
     1321 gcggtagcta ccttgccgtc cagcaggtgg gccatcagct gagcgccata gcagatgcct
     1381 aaaacaggaa tacccagttc aaagatctct tttgaacagc gaggagaatc gtccccatat
     1441 acactgttag gtccgccggt aaaaatgatt ccctttgggt tcatctcttt aattttctca
     1501 atcggcatac tgtacggatg tacttcacaa tatacgttgc attctcttac tcttcttgca
     1561 attaactgat tatactggcc gccaaaatcc agtacaataa tcatctcttt ttccacgagt
     1621 attcctccta taattcttca ctgttgtcgc agtctgcaaa aggggaaact nnnnnnnnnn
     1681 ttattataag acactctctc ccgcttggca acatcatttt ctaaaactcc agcacctttc
     1741 tgattccagt gtagccgcct gctgtaaacg gctctcccac agtgacataa ccgtttcttt
     1801 cgtaaaagcg gttaagcggt tcatttccca gctgacagtc taaacggatt ccccttttcc
     1861 cctgttttct ggcgtaatct tctatcagct ctaaaaacgc agaaccagct cctggaattc
     1921 ctgttctgga agccagatga tgaacataaa aatactcccg gcttccatcc tcccatctgt
     1981 cgtcttcttc cagtaaggtt gtcactccag ctgcttttcc ctcttttata aggaaaaaca
     2041 gatgtccagc cctggcctga gcgcggaaat attcttctga ataaaaatcc agatattcct
     2101 catcgttcca ctgcttcatc cccctgctct ccatccagtc aatcctctcc tggatcacct
     2161 gaataaactc aggaatctgt gtctcctctg cctgtctcat ttcataaaag ctgacttgca
     2221 tttcttcttt ctgtggctct atctctctcg ttccgctccg ttttctcaat attgttcccg
     2281 ctgcttttcc cggcagttcc ctgtacaccc tgccttctgc cctgtttcac cgttttcatt
     2341 cctgctttgt atcttctgct cccagattca ggtacttctt cacatactgt cctgtgtagg
     2401 aaacaggatt ttcagccacc tgctccggcg ttccctgggc aatcacagtt ccacccttat
     2461 ctcctccgtt tggaccaatg tcaatcagat aatccgccgt cttaatcaca tccagattat
     2521 gctcaatgac aactactgta tttccaccgt ccgaaaggcg tctgagaatc tcgatcaatt
     2581 tgtgtacgtc ggcaaaatga agtcccgtcg tcggctcgtc caaaatataa atcgtttttc
     2641 ccgttccccg cttgctcagc tctgtggcca gcttgatacg ctgggcttct ccgcctgaca
     2701 gctgtgtgga cggctggccc agacggacgt aggaaagtcc cacatcattc agcgtctcga
     2761 tctttctgta gatggacggc acattttcaa agaagtgcag agcctcctcc actgtcatat
     2821 ttaaaacgtc ataaatactc ttgcccttgt atttcacctc cagtgtctca cggttatacc
     2881 tttttcctcc gcagacctcg cagggcacat acacgtccgg aagaaaatgc atctctattt
     2941 taataattcc gtctccgctg caggcttcgc accgcccgcc cttcttatta aagctgaatc
     3001 ttcctttatt ataacccttg gctttcgcat caggcgtaga cgcaaataga tcccggatca
     3061 gatcaaatgc acctgtgtag gtcgccggat tggaacgagg cgtccgcccg ataggagact
     3121 ggtcgatggc aataatctta tccagctgct ccgtcccctg gatttcctta tgcttgcccg
     3181 gaattgtcct ggcccggttc agctttttcg ccagagcctt atacaaaatc tcgtttacca
     3241 aagagctttt tccagaaccg gaaactcctg tcacacaggt catcacgccc aagggaaaag
     3301 aaacgtcgat attctttaag ttgttttctg ccgctccctt tacggtgatc cacccggtcg
     3361 gcttcctgcg ctctgttgga acaggaatct tgattctgcc gctcagataa gctcctgtaa
     3421 tagagtcttt gcacttcatg atctgcttcg ccgtgcctac ggccaccaca tttccaccgt
     3481 gttctcctgc tccaggtccg atatccacaa tacagtccgc agccagcatg gtatcttcgt
     3541 catgctccac caccagcacg gtatttccca gatctctaag gtgcagaagc gtctttaaca
     3601 gcttatcgtt atccttctgg tgaagtccga tgctgggctc gtccagaatg taggcgacgc
     3661 ctaccagtcc cgaaccaatc tgagtcgcca ggcggattct ctgggcctct cctccggaca
     3721 gcgttcccgt cgctctggct aaagtcagat aatccagtcc cacgtcaatc agaaagctga
     3781 ctctggccct gatctccttt aaaatcggcg ctccgatggt ctcctgcatg acagtcagat
     3841 tcagcccatc gataaattcc ctgtatttga caatggacat gttggtggcc tcgaaaatat
     3901 ttttcccgcc taccgtcacc gccagagcct cttttttcag tctctggccc ttgcagacag
     3961 gacaaggcgt aatccgcata taagtctcat attcagcctt catggcatca gaaaaagtct
     4021 cccgatactt ccggttcata ttctgaatca gtccctcgaa ggccacatcg tagacgccct
     4081 ctcctctctg gcccttgtag cgcaccttca ggactttccc cccggttccg tgaatcagga
     4141 cgtcgtgaat ctccttgggg taatcccgaa acggtgtgtc caggctgaaa tggtactcct
     4201 ccaccaacgc gtccagaatc gcacgcgtaa agctgccttt atccgtgcag gactgccatc
     4261 ccatgcccac aatcgccccc tggctgatgc tcaggctctt gtcaggaatc agcagatcct
     4321 cgtcaaactc catcttatag cccagtccat agcagtcagg gcaggcgccg aacggattat
     4381 tgaaagaaaa gcttctgggt tccacctcgt ccacgctgat tccacagtca gggcaggcaa
     4441 aattctgact gaaattcatg gattcctggt caggaatatc cacagtcatc agacctcctg
     4501 tcagctccat caccgtctca atggaatctg tcagacgctt ctcaatgccc ggcttcacca
     4561 ccagacgatc caccacaatc tcaatattgt gcttaatatt cttatccagc ttaatctcct
     4621 cagaaagctc gtacaggctt ccgtcaatcc ggacgcggac gtagccgccc tttctggcgt
     4681 gctccagcac cttcacatgc tctcccttgc gcccacggac tacaggagcc agaagctgga
     4741 ttttcgtccg ctccggcatg gccataatct gatccaccat ctgatcaatg gtctgcctgt
     4801 gaatctcccg gccgcacctg gggcagtggg gaataccgat tctggcgtag agaagacgca
     4861 tataatcata aatctctgtc acagttccca ctgtagatct gggattcctg ttcgtggact
     4921 tctgatcaat ggaaatagcc ggggaaagtc cttctatgct ctccacatcc ggcttctcca
     4981 tctgtcccag gaactgcctt gcataggaag acagcgattc catgtagcgg cgctgtccct
     5041 ccgcataaat cgtgtcaaaa gccagggaag actttccgga gccggaaagt cctgtcaaaa
     5101 ctaccagctc atttctcggg atatctaccg atatattttt cagattgtgc tcattcgctc
     5161 ctcgtatttt aatgtactgc ttcgccatac cgtactcctt gctgacctgt gttccatttt
     5221 cgttgtaagt tattataccg cattcactaa gctcgacaaa acctcgctaa gtgtctgggt
     5281 atgactcgca ctaacctcat actccgcctg cggctcgtat tcgctaagtg ctcatattat
     5341 accatatctg caggaaagca agtggctgcg aagcagacat ttgttttcac ctgatatggt
     5401 aacgacaaaa tgttttagct gccaaaggca gcggcaggtg tgcgcagcac aactgcattt
     5461 tggagttatt ataccacatc cacctttatt tttcaaacgt ttgttcgatt attttgcagg
     5521 cattttccag ttttcccgca gtcgaaaaca gcccgggcag agaactgtct ttccctgtcc
     5581 ggactgccat aaaagcttct aatctgtatc gagcttctgc ttactagacg ttatcctgaa
     5641 tttctgtatg gtctctttcc accttttcct cagcatctgc gcctgcagtt tccaaattct
     5701 cctttttcag aatctccatg aattcctcgc ctgtgatggt ctccttctcc agaagatagg
     5761 ctgccagctc atgaagcttt tcctcgtttt ccttcaaaat ctggcaggcc ttatcatggg
     5821 cctgacggac tgtgtcaatg acttcctcgt cgatccgcat cgccgtgtgc tcggagcagg
     5881 ccagggacgc gtctccgccc agatactggt tgctgactgt ctccagggcc accattccga
     5941 actgctcgct cattccgaac cgcgtcacca tggcgcgggc aatcctggtc gcctgctcga
     6001 tgtcattgga agcgccggtt gtaatagagt ggaaaatcag ttcctccgcc gcccggcctc
     6061 ctgtcagcgt cacaatctta ttaaacgcct cgtcccggct catgagaaat cgctgatcct
     6121 cctcaatctg catcgtgtat cccagagccc cgctggttct gggaataatc gtgatcttat
     6181 gcaccggcgc agaatgactc tgcatcgccg ctacgagcgc atggccgatt tcatggtagg
     6241 acacaatctt cttctcattg acagaaacct ctgcatcctt cctctgatat ccggcaatga
     6301 caacctccac gctctcttcc aggtcctgct gcgaaaccat ccttctgccc atacggaccg
     6361 ccctcagagc agcttcattg acaatattgg ccaaatccgc tccgctggcg ccgctggtag
     6421 cccgggcaat ctcattataa tcaaccgttt catccatctt cacgccacgg gcagaaacct
     6481 ttaaaatggc ctccctgcct ctcatgtcag gcagctccac aggaattctt ctgtcgaaac
     6541 ggcccggacg cagaagcgct ttatcgagag aatccggccg gttggtggcg gccaggatga
     6601 caactccctt ctgaccgtca aatccatcca tctccgtcag aagctggttt aaagtctgct
     6661 ctctctcgtc attgcctcct atatttccat cacgcttctt tccaatcgta tcaatctcat
     6721 caataaatac gatacagggg gccttctcat tagcctgttt aaataaatcc cttaccttag
     6781 cggctcccat gcccacaaac atctctacaa actccgatcc ggaaatagag aaaaacggca
     6841 cgtgggcctc tcctgccacc gccttggcaa gcaatgtttt tcctgttcct ggaggaccga
     6901 ctaacagtgc acccttagga agcgtcgctc cgatatccgt atatttctgg gggttgtgaa
     6961 gaaaatccac aatctccttt aaagcttcct tggcctcctc ctggcccgct acgtctgcaa
     7021 aggtcttgcc cgtctcagac tccgcgtaaa ttttggcatt ggactttccg aaggtcatgg
     7081 cgttgggccc tcccatgcgc ttcatcattg cccggctcat cagctgcccg atcagaacca
     7141 gaatgacaaa cggcgcaatc caggtaagca aaaagtccag cagcggcgag gcctgggtct
     7201 gaatctcaga actgaatctg gcgtctgtgc cggccagccg ttccgtaata ttatctcctg
     7261 gcatcaggcc agtcttgtga acagcgcccc tgctgtcgcc ctttaaggta tacataacct
     7321 catcattagt agtcacatag acctcgtcta cttcccctgc attcagggaa gtcagaaatt
     7381 cgtcgtaacg tccctccact gtcttatcca tgacagaagg aaacacaaaa atattcagaa
     7441 gcagcagcac cagcataacg atcccgtaat aatacagaaa cgaacgcttg ggcggtttat
     7501 tctgatcaga atcccttttt tccataaact tcttctcctc atcgtctctt tacatcattg
     7561 gcaaatccgg cagttttata ccttctgccc gttacacagc ctacaataca actgcatttt
     7621 atatttgtca atatattatt ataaatattt atttactttt aatatttatt gatctgatat
     7681 aaaaaatgtg ttatgatggg aacaaaatac ctgttcatat cagcttcagg aggtgtctgt
     7741 atggatgatg aaaagctgcg gacagccgga acgcattttt tagaatttgc attttctttt
     7801 ctgacctttg ccaagtgcca gtaccagtcc gctaatcata ttaaaatcaa ctctcttccc
     7861 ttttttacgc tgtccattct ggcagaccaa aaggatgaga actataccat gtctgatctg
     7921 gctgataagc tccagattac aaagcagcag ctttccaagc tgattaacga tttagaggat
     7981 aaggcgctgg tagaacggat tcacgatacc gcaaaccgcc gccgcgtcta catcaggatt
     8041 tcgccctgcg gcctggaggc aatggaacgc ttaaaagaaa ccatgctgga gacaaccatt
     8101 gccgccctgc atatttataa tgaggaagaa ctggaaacgc tgaattcctg tctggaatcg
     8161 ctgacacccc tgatggaaaa atttcattta aaagaatgcg gcgaatgata ttatcttttt
     8221 ctttagacaa acataccatg catatttaat cactcttctt gctatgaaaa aataatagaa
     8281 attatgtgtc tgccatatcc tgcaggcact tttttcttcc cctaaaatct ccattttatc
     8341 tgcatctgcc agttccaact ttccatactt tcccttatcc gaagtataat agccacgtaa
     8401 tgcagttagg aatttcgaaa aatattgact tcaaaaagaa aaaaggagag tgcattcatt
     8461 atgagaaagc agactaaatt agttgcagtt ctttctgcag cagctttact cgcagtaggc
     8521 gcttccatga catccttcgc aggttgggag aaggacgagg atggtatctg gcactactac
     8581 gacagcgatg acgagatggt aacagacgag tggagaaagg acggctccaa gtggttctat
     8641 ctcgatgagg atggcaacat gctgacagag gcttgggtag acgatgagta ctacgtaggc
     8701 gctgacggtg ctatggttaa aaatgactgg gttaagacaa cagctgacga ggatgtttct
     8761 gatccagagg atgatggaga caactggtac tacttcggtt ccaatggtaa gaaggtagag
     8821 gatgactcca agaagatcaa cggaaagaca tactacttca acgaagacgg cgagatgaga
     8881 tacggctggt acgaggataa cggcgacgta ttctaccttg gcggcgagga tgagggctgg
     8941 agagcagaga gccagtggtt atggcttgca ttaccagatg aagacgaagt tgacagaaac
     9001 ggtgtaaact tctgtgatga tgacagcgct tgctctgtac attgcgacga ggaaggctgg
     9061 tactacttcg gttccaacgg taagatgtat aaagaagcag ctaagaagaa agtaaacgga
     9121 aagtactact tcttcaacgc tcacggccag atgctctacg agtggatcaa caatcagaag
     9181 tacagagtat ccagctcttc tgatcttgta agcggaaatg gatatacagc accaggcgca
     9241 gcatcttcca gcaatggtat cttagatgat aacgctaact accagggaag cagccagatc
     9301 tggaatatgc agtactccaa cgtagtagag gacggttcca gagcaaacgg ctggtatgag
     9361 atcgatggtt ctgcagatac aggcgaggac ggcgatacag actggtacta cttcgatgac
     9421 ggtgaggctg agagagcaga cgctggcaaa gacttcgtta ctgtagatgg tgatggagct
     9481 gatgtattca gagctaagat caagatcaac ggaaaatact tctgcttcaa tgagatgggc
     9541 cagatgcaga caggtcttca gtacatcggt gctgatcatg cattctactt ctttgatgag
     9601 aacggctaca tgcagacagg taaggagaca aatgtagagg acgacgacga ttcctacaac
     9661 ttctacttca tcacaaagaa cggcaagaac ggccagggcc agatgggtga gaaagacaac
     9721 tacctgtact tcggtggtaa gagacttgag gcagacgatg actacagaat ctacttcttt
     9781 gatggaaaat attaccttgt aaacaacaag ggtaagatcc aggattccaa gtccaagaag
     9841 tacgatgttg agaatggaaa cggcatgaca gaggctaagt ttacattcag aaatgatggt
     9901 tctatctcta aggtagaaat tgagggtaca aatggtaact attcagaggt tccagctgca
     9961 acatggcagg cagatgctac atacccggag attgctctgt acgacggcta cttcacatat
    10021 gatacagatc accagaatgc tttagtatgg ttaactgagg ctcagtacaa tgcgctcggc
    10081 agaaatcagt aatctctcat tgagaattcg ctaatttctt tataaaataa ctaatcaaac
    10141 agcggtacac tacttttgtg atattgaaaa atatcagaag gcagcgtatc gctgtttttg
    10201 caatatgccc ttgtggcata aaaagagccc tttccataga atggagggta agccgcccgg
    10261 ctctgtggtt tcccacacgg ttactatata gcaaggtcta cagcctgaca atctctattt
    10321 gcatttcttt ctgatttgat ataaaattgt tcgttctttg aaaaaaatta ggaaaattta
    10381 gatttgagcg aatttatcaa agctacttga attataggaa gtgattggat ataatagaaa
    10441 tacagaaagc acccacccca aaaatggatg cctctagttg gattttatgt ccttaaggac
    10501 acgcccatcc tgttggcaga caggatgggc atttttactt tcgcttgttt ctcttatcga
    10561 gaaaggcgat gaatgcaatg ataaatccag caaaggctat gagcaagctc aatatcccta
    10621 tgataaccat gatagtctca tatgctgtca tcagcaccac ctcctttcct atgtactcct
    10681 ggcgaaccag ggcaggtttg gaggcatacc actcctgtca tgagtgcttt ccgtaacgtc
    10741 attttatcac ggaaatttat atggttcaat gaaaaaattt catttcaaac ttctataact
    10801 tctaaatcat tttacagcta aatcgctcat tctatccggt tataggatgg ataattttta
    10861 tcccacaagc acaaatttta atttatcata aaaacaggag taccactcct gccattatta
    10921 tgacagttgt gatactcctg aaatcatctt atgtaattaa tatgactcta ttaattagtt
    10981 aagaccacgc cagtcctcaa tgatagtgcc gccaacattc ttgtat
//
LOCUS       DBMDUW010000072        10736 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_3036_length_10736_cov_2.627833, whole genome shotgun sequence.
ACCESSION   DBMDUW010000072 DBMDUW010000000
VERSION     DBMDUW010000072.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 10736)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 10736)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10736
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3036_length_10736_cov_2.627833"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            224..1480
                     /locus_tag="ACZPCR_10905"
     CDS             224..1480
                     /locus_tag="ACZPCR_10905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009461926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose ABC transporter substrate-binding
                     protein"
                     /protein_id="HIR1231410.1"
                     /translation="MKKRFLALTMASLMAFSMVGCSGGNKEAADTTAANGETQAAGEE
                     TAKKSDLNVGVFYYTYSDTYITSVRTALDAALTEAGVKFQDFDGNSNQTTQNEQIDTA
                     IAQGVNLLVVNIVTSGSVDASQAIVDKAKAADIPVIFFNRAVETDEDEGKVLGSYEKC
                     AFVGTDAPEAGHMQGQLIGEYLIENYDTVDLNGDGKISYAMFMGQLGNVEAIYRTQFG
                     VEDANKVLEEAGKPALEYFDPSNTDCYQVDQDGNWSATAANNYMVTNLAQYNEANGNM
                     IELVICNNDGMAEGAISALNDKGYNLGTADSKTIPVFGVDATDAAKQYIADGKMTGTI
                     KQDAEGMADGIAYLVNNVAEGKEVMADTDDFNKSETVTNKIYIPYATYTGEEGAAAEE
                     TEAAEEAAEESTEAAEETTAAETEAE"
     gene            1729..3225
                     /locus_tag="ACZPCR_10910"
     CDS             1729..3225
                     /locus_tag="ACZPCR_10910"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009461927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HIR1231411.1"
                     /translation="MGQEVLLEMKNITKEFPGVKALNQVSLTVKKGTVHALMGENGAG
                     KSTLMKCLFGMYSKDGGQIFLEGKEVNFKNSKEALENGVAMVHQELNQALKRNVMDNI
                     WLGRYPKVGGVMIDEKKMYEDTKEVFQELGIDVDPRRIMSTMPVSQRQMAEIAKAVSF
                     NSKIIVFDEPTSSLNEQEVEHLFKIINMLRDKGCGIIYISHKMAEILRIADEVTVMRD
                     GTWIATKPAKDLTTEEIIKLMVGRELSNQFPPKTNKPGEVALEVEGLTAQYSLLKDVS
                     FKVRRGEIVGLAGLDGSGRTETLENIFGIATRKSGTIKLDGKQVLNRNARESIKNGFA
                     MLTEERRATGIFGILNIRENTVISSLKKHRKGIALSEKSMRADTGWSIKAMRTKTPTQ
                     ETKIRSLSGGNQQKVILGRWLLTEPEVLLLDEPTRGIDVGAKYEIYQLIIDLANKGKI
                     VMMVSSEMPELLGVCDRILVMSGGRLAGEVDAKNTTQEEIMTLAAKYV"
     gene            3242..4312
                     /locus_tag="ACZPCR_10915"
     CDS             3242..4312
                     /locus_tag="ACZPCR_10915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012200260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/methyl galactoside ABC transporter
                     permease MglC"
                     /protein_id="HIR1231412.1"
                     /translation="MRMIENYKAKVDNYKSLDAKDKKLFWKEAAINNALYVLLLIAII
                     YTFMQNSRFLAPASIVNIISLSAANLPIACGIAGCIVLTGTDLSAGRVVGLTACISAS
                     LLQSLDYATKMFPGMPPLPIPVVILVVLAVGGVVGYVNGFFVAKFQLHPFIVTLATQL
                     IVYGLLLMYIMINGNNGQPLSGLDDSFKTFVTGSILKIGGVAIPNYVWYGMIVVAIMW
                     FIWNKTTFGKNMFAVGSNPEAANVSGVNVMRTTILVHTLAGMMYGVTGFIESARIGSN
                     QANTGLNYECDAIAACVIGGVSFVGGTGKISGVVMGVFLLRIIFVALNFLSINMNMQY
                     VIKGLIILVACAIDMRKYLVRK"
     gene            4453..5079
                     /locus_tag="ACZPCR_10920"
     CDS             4453..5079
                     /locus_tag="ACZPCR_10920"
                     /inference="COORDINATES: protein motif:HMM:NF021028.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="InlB B-repeat-containing protein"
                     /protein_id="HIR1231413.1"
                     /translation="MEEQDKKQLETEREEDKEQENPMIRKRLFGRGIYGSKDVPIRLL
                     DGLIAFLMIAIVGMIAYFAFHGGYTVTFDSQGGTEVKSQKLKYGDTVAEPEDPVRQGY
                     EFAGWYTESGALEWYFPEASVEGDITLYAHWIPAKITVKFELDGGNIGGEEEAAPVQV
                     TFEDAYGKLPVPEKEGYQFAGWSYSGQMIESSTIVTTNGEHVLTAVWE"
     gene            5475..8612
                     /gene="ileS"
                     /locus_tag="ACZPCR_10925"
     CDS             5475..8612
                     /gene="ileS"
                     /locus_tag="ACZPCR_10925"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003504438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HIR1231414.1"
                     /translation="MYDKVSTDMNFVEREKKTEKFWADNQIFEKSIESRKQGPTYTFY
                     DGPPTANGKPHIGHVLTRVIKDMIPRYRTMKGYMVPRKAGWDTHGLPVELEVEKMLGL
                     DGKEQIEQYGLDPFIGHCKESVWKYKGMWEDFSATVGFWADMDHPYVTYHNDFIESEW
                     WALKQIWEKGLLYKGFKIVPYCPRCGTPLSSHEVAQGYKDVKERSAIAKFKVKGEDAY
                     ILAWTTTPWTLPSNVALCVHPDDTYVKVQMKEDGTVYYMAEALCNTVLGEGTYEVKES
                     FTGKDLEYKEYEPLFDCAGEICAKQHKKAYFVVCDTYVTLTDGTGVVHIAPAFGEDDS
                     KVGRKYDLPFVQLVDAKGEMTKETPWPGTFCKKADPLVLKDLDERGLLFSAPNFEHSY
                     PHCWRCDTPLIYYARESWFIKMTAVKDDLIRNNNTINWIPESIGKGRFGDWLENVQDW
                     GVSRNRYWGTPLNIWECECGCQHSIGSIEELKSMSDNCPEDIELHRPFIDAVTIKCPK
                     CGREMHRVPEVIDCWFDSGSMPFAQHHYPFENQDLFEQQFPADFISEAVDQTRGWFYS
                     LLAISTLLFNKAPYKNVIVLGHVQDENGQKMSKSKGNAVDPFEALSTYGADAIRWYFY
                     INSAPWLPNRFHGKAVMEGQRKFMGTLWNTYAFFVLYANIDQFDATKYSLEYDKLPVM
                     DKWLLSKLNTLVKEVDDNLGNYRIPEAARALQDFVDDMSNWYVRRSRERFWAKGMEQD
                     KINAYMTLYTALVTVSKTAAPMIPFMCEDIYQNLVRNIDKTAPESVHLCSFPEVQESF
                     IDKELEAYMDEVLKVVVFGRAARNTANIKNRQPIGKMFVKAERSLPEFYQEIIEDELN
                     VKSVEFTDDVRAFTSYTFKPQLRTVGPKYGKQLGNIKKALSEIDGNSAMDTLKEKGAL
                     TFDFNGEEVVLTEEDLLIDAAQVEGYVSEGDNTVMVVLDTNLTPELLEEGFVRELISK
                     IQTMRKEAGFEVMNHIRVFAEGNEKISAIFAAHGEEIRSEVLADEIVTGQTGGYSKEW
                     SINGEKVVLGVEKTA"
     gene            8696..>10736
                     /locus_tag="ACZPCR_10930"
     CDS             8696..>10736
                     /locus_tag="ACZPCR_10930"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HIR1231415.1"
                     /translation="MQTFDKETLKESIIDNMKNLYRKTIDEATPQQVYQAVAYAVKDV
                     IIDQWIATHKAYDENDAKIVYYLSMEFLMGRALGNNMINIGAQKEIREVLAELGFDLN
                     TIEDQEPDPALGNGGLGRLAACFLDSLATLGYPAYGCGIRYHYGMFKQKIENGYQIEV
                     PDEWLKNGYPFELRRAEYATEVKFGGYVKTVWENGRNKFIQEGYRSVMAIPYDMPIVG
                     YGNNMVNTLRIWDAQPLNSFSLQAFDKGDYQKAVEEENLAKNLVEVLYPNDNHYSGKE
                     LRLKQQYFFISASVQRAVAKYKETHSDIHKLPEKVIFQLNDTHPTVAIAELMRILLDV
                     EGLEWDEAWDITTKCCAYTNHTIMSEALEKWPIELFSRLLPRIYQIVEEINRRFLIEV
                     ERHYPGNYEKVKKMAIIFDGQVKMAHLAIVAGFSVNGVARLHTEILKNQELRDFYEMM
                     PEKFNNKTNGITQRRFLLHGNPELAAWVTDKIGSEWITDLSKIGKLKIYADDKKCQQE
                     FMNIKYHNKLRLAKYIKEHNGIDVDPRSIFDVQVKRLHEYKRQLLNILHIMYLYNQLK
                     DNPNMEMVPRTFIFGAKAAAGYQIAKKTIKLINSVANVINNDRSINGKIKVVFIEDYR
                     VSNAELIFAAADVSEQISTASKEASGTGNMKFMLNGALTLGTMDGANVEIVEEVGQ"
BASE COUNT         3110 a         2217 c         2920 g         2489 t
ORIGIN      
        1 gaatatcaga aaattttatt cctgttcgat tgacaggctg caaagtgttt ggcgaagtat
       61 acaagaaaag gtgggaaaat caacaggaga attgaaattt gtacaagttt tgttgattat
      121 tctatgtact tttgttgaaa aaaactctat aatcacttat gaaagatatg tggaatacac
      181 atacaaataa agtttaatta caaaatggga ggatgatgta attatgaaga aaagatttct
      241 tgcactcact atggcgtctt taatggcatt cagcatggta ggatgctccg gcggcaacaa
      301 agaggctgct gacacaactg cagcaaacgg cgagacacag gcagctggtg aagagacagc
      361 taaaaagtct gatttaaatg taggtgtatt ctactacaca tacagcgata catatatcac
      421 aagcgttcgt acagctcttg acgcagctct tacagaggct ggtgttaagt tccaggactt
      481 tgatggaaac agcaaccaga caacacagaa tgagcagatc gatacagcta tcgctcaggg
      541 tgttaatctc ttagttgtaa acattgttac atccggttct gtagacgctt cccaggctat
      601 cgtagataag gctaaggcag ctgatatccc ggttatcttc ttcaaccgtg cagttgagac
      661 tgacgaggat gagggcaagg tacttggaag ctatgagaag tgtgcattcg taggaacaga
      721 tgctcctgag gctggacata tgcagggaca gttaatcggt gaatacctga ttgagaacta
      781 cgacacagtt gacttaaacg gcgacggaaa gatcagctac gctatgttca tgggacagct
      841 tggaaacgta gaggctatct accgtacaca gttcggcgta gaggatgcaa acaaggttct
      901 tgaggaggct ggaaagccgg ctctggagta cttcgacccg tccaatactg actgctacca
      961 ggtagaccag gatggaaact ggagtgctac agcagctaac aactacatgg taacaaacct
     1021 ggctcagtac aatgaggcta acggcaacat gatcgagctg gttatctgca ataacgacgg
     1081 tatggcagag ggtgctatct ccgctctgaa cgataaggga tacaaccttg gaacagcaga
     1141 cagcaagaca attccggtat tcggcgttga cgctacagat gctgctaagc agtacattgc
     1201 agacggcaag atgacaggta ctatcaagca ggatgcagag ggtatggcag acggtatcgc
     1261 ttacctggta aacaacgtag cagagggtaa ggaagttatg gctgatacag acgacttcaa
     1321 caagtctgag acagtaacta acaagattta cattccatac gctacataca caggcgagga
     1381 aggtgcagca gctgaggaga cagaagcagc tgaggaagca gcagaagagt ccacagaggc
     1441 agctgaggag acaacagcag ctgagacaga ggctgagtaa tttgtaaatt tgaataaagt
     1501 gaaagcggct gtcggctggc ggcagccgct ttccttgtgc ttaaaatgta agcaggggaa
     1561 gcatagggca gtgaaggctg ctccggcagg ctgcaaggtc tgcaaaaaac gaagtgatcg
     1621 gaaaaagggg aagagaatct gcagatgata atatgctgcg gtgtttcacc tggattggta
     1681 cggaatttga ccgggcacat tccaggaaat gaaaggagga aatgagttat gggacaggaa
     1741 gttttactcg agatgaaaaa catcactaaa gagtttcctg gcgttaaagc tctcaatcaa
     1801 gtttctctga ctgtcaaaaa aggaacagta cacgctctga tgggtgaaaa cggagcaggt
     1861 aaatctacac tgatgaaatg cctcttcggt atgtacagca aagacggcgg tcagattttc
     1921 ctggaaggaa aagaagtaaa tttcaaaaat tccaaggagg ccctggaaaa cggtgttgcc
     1981 atggtacacc aggagttaaa ccaggcgtta aagagaaatg ttatggataa tatctggctg
     2041 ggacgttatc caaaagtcgg cggagtcatg atcgatgaaa agaagatgta cgaagacaca
     2101 aaggaagtct tccaggagct tggcattgat gtagatccga gacgtattat gagtaccatg
     2161 cctgtttcac agagacagat ggcggagatt gccaaggcag tttcctttaa ttctaagatc
     2221 attgtatttg acgagcctac gtcttctctt aatgagcagg aagtagagca cttattcaag
     2281 attattaaca tgctccgtga caagggctgc ggaatcatct atatctccca taagatggca
     2341 gagattctgc ggattgccga tgaagttacg gttatgcgtg acggcacatg gattgccaca
     2401 aaaccggcga aagatctgac gacagaagag attattaagc tgatggttgg acgtgaactg
     2461 agcaatcagt tcccgccaaa gacaaataag ccaggagagg ttgccctgga ggtagaggga
     2521 ctgacagccc agtactccct tttaaaggat gtatccttta aggtgaggag aggcgaaatc
     2581 gtaggtctgg caggtctgga tggcagcggc cgtacagaaa cgctggaaaa tattttcggt
     2641 attgcaacga gaaagtcagg aaccattaaa ttagacggaa agcaggtatt gaaccgaaat
     2701 gccagagaat ccattaagaa tggctttgcc atgctgacag aagagcgccg cgcaaccggt
     2761 atcttcggaa ttctgaacat cagggaaaat accgttatat caagccttaa aaagcataga
     2821 aagggtattg ccttaagtga gaagtccatg cgggctgaca caggctggtc cattaaggca
     2881 atgcggacca aaacgcctac acaggagacg aaaatcagaa gcctttccgg cggtaaccag
     2941 cagaaggtta ttctgggaag atggctttta acagagcctg aagttctgct tttggacgag
     3001 ccgacacggg gcatcgatgt aggtgcaaag tatgaaatct accagttaat catcgacctt
     3061 gcaaacaagg gcaagattgt tatgatggta tcctcagaga tgcctgaact tctcggtgtg
     3121 tgcgacagaa ttcttgttat gtccggcgga cgtctggcag gcgaggttga cgcaaagaat
     3181 accacacagg aagagattat gacacttgct gcaaaatacg tgtagaggag gttttggtca
     3241 gatgagaatg attgaaaatt ataaagcaaa agtagataac tataagtctc ttgacgcaaa
     3301 ggataaaaag ttattctgga aagaagccgc aattaataat gcgctttatg tactgttact
     3361 tatcgcaatt atttatacat ttatgcagaa ctccaggttc ctggctcctg catctatcgt
     3421 aaatattatc agcctttccg cggcgaacct tcctatcgcc tgcggtattg caggatgtat
     3481 tgtactgaca ggtacagacc tttctgccgg acgagtagta ggtttgacag catgtatttc
     3541 tgcatctctg cttcagtctt tagattatgc cactaagatg ttcccaggca tgccgccgct
     3601 tccgattccg gttgttattc tggtagtgct tgcagtgggc ggcgttgttg gatatgtaaa
     3661 tggtttcttc gttgctaaat tccagctcca cccattcatc gtaaccctgg caactcagct
     3721 gattgtttat ggtctgctgt taatgtacat catgatcaac ggcaataacg gacagcctct
     3781 gtctggtctt gatgattcct tcaagacctt cgttacaggc agcatcttaa agattggcgg
     3841 cgttgcgatt ccgaactacg tatggtacgg catgattgta gtggccatca tgtggttcat
     3901 ctggaataag actacatttg gtaaaaacat gtttgcagtt ggttccaacc cggaggcagc
     3961 taacgtatct ggtgtaaacg taatgagaac cacaattctg gtacacacac tggcaggtat
     4021 gatgtacggt gtgacaggct ttattgagtc tgcacgtatc ggttccaatc aggctaatac
     4081 aggtctgaac tacgagtgtg acgctatcgc agcctgcgtt atcggcggcg tatccttcgt
     4141 aggtggtact ggtaagatca gcggcgttgt tatgggtgta ttcttactca gaatcatctt
     4201 cgttgccctg aacttcctct ctatcaatat gaacatgcag tatgtgatta agggtcttat
     4261 tatcctggtt gcctgcgcta tcgatatgag aaagtatctg gtaagaaagt aatgaatctg
     4321 cggggagtat aggcttccgg cagaagggga ttcacaggaa gcagagatgc ttaggggaat
     4381 cccctttctt tattttatag gaaactgcat ttgatgaatt cttttttata gggcagtatg
     4441 gaggaaaaag agatggaaga acaggataaa aaacagctgg aaacagaaag agaagaagat
     4501 aaggagcagg aaaatcccat gatccgaaaa agactgttcg ggcggggaat ttatggaagc
     4561 aaggatgttc ccatacgcct gctggacggg ctgattgctt ttttgatgat tgcaattgtg
     4621 ggaatgattg cctattttgc ctttcatggc ggctataccg ttacgttcga ttcacaggga
     4681 ggaacagagg taaaatccca gaagctgaag tatggtgata cagtggcaga gccggaagat
     4741 ccagtcagac aggggtatga atttgccggc tggtacacag agagcggagc gcttgagtgg
     4801 tattttccag aagcctcagt ggaaggtgat atcaccctgt atgctcactg gattccagcc
     4861 aaaattacag taaaatttga actggatgga ggcaacatag gaggagagga agaagctgca
     4921 ccagtgcagg ttacttttga agatgcttat ggaaaactcc ctgtccctga aaaggaggga
     4981 taccagtttg ccggctggag ctatagcgga cagatgatag aaagcagtac gattgtgaca
     5041 acgaacgggg agcacgtgct gactgctgtg tgggaataac gggaatgaaa gatacaggaa
     5101 tatcagttga cttttgcagt taaactgttt aaaatagtat actgtacaag taattttata
     5161 tgtttaaacc agaaaaactg tgacggagac agtaaggctt tacggaaagg caaagcgagg
     5221 cagggagggt gagagcctgc tgcgagtagg gaagcactga atatcactcc tgagttgcag
     5281 gctgaacggg atgccttttc gtcatgggct tccttattaa gctgagccgg tgtccgccgt
     5341 tagagggagc gcatatgaag tatgcagtaa caggtggtaa aacgaagtga ttgacagcct
     5401 tcgtcctttt acgggacgga ggctttttac gctttctgca tacacaaaaa ttcaccagac
     5461 aggaggaaaa aaacatgtac gacaaggtct ctactgacat gaattttgtg gagagagaaa
     5521 aaaagacaga gaaattctgg gctgacaatc agatttttga gaagagtatt gaaagccgga
     5581 aacagggccc gacctatact ttttacgacg gtccgcctac cgctaacgga aagccacata
     5641 tcggccacgt tttaacacgc gttatcaagg atatgattcc aagataccgc acaatgaagg
     5701 gatatatggt tccgagaaag gccggctggg atacccacgg acttccagta gagctggaag
     5761 tagagaaaat gctgggtctg gacggcaaag agcagatcga gcagtacggc ctggatcctt
     5821 ttatcggcca ctgcaaggag agcgtgtgga aatacaaggg catgtgggag gatttctctg
     5881 ccactgtcgg tttctgggct gatatggatc acccatacgt tacctaccac aatgacttta
     5941 ttgagtcaga atggtgggct ctgaagcaga tctgggagaa gggactgctc tacaagggct
     6001 ttaagattgt gccttactgc ccgcgctgcg gaactccgct gtccagccat gaggttgccc
     6061 agggatataa ggacgtgaag gagcgctccg ctattgccaa gtttaaggta aagggtgagg
     6121 atgcgtatat tctggcatgg accacaactc cgtggacact gccttccaac gtggctctct
     6181 gtgtacatcc ggatgatact tacgtaaaag tccagatgaa ggaagacggc acagtctact
     6241 acatggctga ggccctctgc aatacagttc tcggcgaggg aacctacgag gtaaaagaaa
     6301 gttttacggg aaaagattta gagtataagg agtatgagcc gttatttgac tgtgcaggcg
     6361 agatctgcgc aaagcagcac aagaaggcat actttgtagt ctgtgacacc tatgttactc
     6421 tgacagacgg tacaggagta gttcacattg ccccggcctt cggtgaggac gacagcaagg
     6481 tgggaagaaa gtacgatctt ccgttcgtac agttagtaga tgcaaagggc gagatgacaa
     6541 aggagactcc gtggccagga accttctgca aaaaggcaga cccgctggtt cttaaggatc
     6601 tggacgagag aggcctctta ttctccgctc cgaactttga gcacagctat cctcactgct
     6661 ggagatgcga tactcctctg atctactatg cgagagaatc ctggtttatt aagatgacag
     6721 cggtaaagga cgacctgatc cgcaacaaca acaccatcaa ctggattccg gagagcattg
     6781 gaaagggacg tttcggcgac tggctggaga acgtacagga ctggggcgtt tccagaaacc
     6841 gctactgggg aactcctctc aatatctggg agtgcgagtg cggctgccag cattccatcg
     6901 gaagcatcga ggagttaaag agcatgtctg acaactgccc ggaggatatc gagctgcacc
     6961 gtccatttat cgacgcagtg actatcaagt gtccgaagtg cggcagggag atgcaccgtg
     7021 ttccggaggt aatcgactgc tggttcgact caggttccat gccgtttgca cagcatcact
     7081 atccatttga gaatcaggat ctgtttgagc agcagttccc ggcagacttt atctccgagg
     7141 ctgtggatca gacgagagga tggttctact ccctcctggc aatttcaact ctgctcttta
     7201 acaaggctcc gtataagaac gttatcgtgc tgggccatgt gcaggatgag aacggccaga
     7261 agatgagcaa gtccaaggga aatgcagtag atccgtttga ggctctctct acctacggcg
     7321 cagacgccat ccgctggtat ttctacatca acagcgctcc atggcttccg aaccgtttcc
     7381 acggcaaggc tgttatggag ggacagagaa agttcatggg aactctctgg aatacctatg
     7441 cgttcttcgt actctatgca aacattgacc agttcgacgc aacgaaatac agcttagagt
     7501 atgacaaact gccggttatg gataaatggc tgctgtccaa gttaaatact ctggtaaaag
     7561 aggtggacga caatcttgga aactacagga ttccagaggc tgcaagagct cttcaggact
     7621 ttgtggacga catgagcaac tggtatgtaa gaagaagccg cgagcgtttc tgggctaagg
     7681 gcatggagca ggataagatc aatgcgtaca tgacgcttta cacagctctt gtgacagttt
     7741 ccaagacggc tgctccgatg attccgttca tgtgcgagga catctaccag aacctggtga
     7801 gaaatattga taagacagct ccagagagcg ttcatctgtg cagcttcccg gaggttcagg
     7861 aaagctttat cgacaaggaa ctggaagcgt acatggacga ggtcttaaag gtggtagtat
     7921 tcggccgcgc tgccagaaat acagcgaata tcaagaaccg ccagccaatt ggaaagatgt
     7981 tcgtgaaggc agagagaagt cttccagagt tctaccagga gatcatcgag gacgagttaa
     8041 atgtaaagag cgtggaattt acagacgatg tgagagcctt tacttcctat acctttaagc
     8101 cgcagttgcg caccgtagga ccgaagtacg gaaagcagct gggaaatatt aagaaggccc
     8161 tgtctgagat tgacggaaac tccgctatgg atactttaaa ggagaaggga gccttaacct
     8221 ttgactttaa cggcgaggag gtcgttctca cagaggagga tcttctgatt gacgcggctc
     8281 aggtagaggg ctacgtctct gagggagaca atacagtgat ggttgtcctg gatacgaacc
     8341 tgactccgga actcctggag gaaggctttg tgagagagct gatcagcaag atccagacca
     8401 tgagaaagga agccggcttc gaggtgatga accacattcg tgtgtttgca gagggaaatg
     8461 agaagatttc cgctatcttt gcagcccacg gcgaggagat caggagcgag gttctggcag
     8521 acgagattgt gactggccag acaggcggat actccaagga gtggagcatt aacggggaaa
     8581 aggtagtgct cggcgttgaa aaaacagcgt agcgaaagcg gaaggaagct gacgggcggg
     8641 gcgaacagtc ccgccctggc cgaaaagcga aaaacgcttg ttaggaggat ggagaatgca
     8701 gacctttgat aaggaaacat tgaaagaaag cattatcgac aatatgaaga acctgtaccg
     8761 gaaaaccatt gacgaggcca cgcctcagca ggtttaccag gcagttgcct atgcggtgaa
     8821 ggacgtaatt attgaccagt ggattgcaac gcataaggcc tacgacgaaa acgacgcgaa
     8881 aatcgtatac tatctgtcca tggaatttct gatgggacgg gcgctgggaa acaatatgat
     8941 caatattgga gcgcagaagg agatcaggga ggttctggca gagctgggct ttgacttaaa
     9001 taccatcgag gatcaggagc cggatccagc tcttggaaac ggaggcctgg gaagactggc
     9061 cgcctgcttt ttagactctc tggctaccct gggctatccg gcatatggct gcggaatccg
     9121 ctaccactat ggtatgttca agcagaagat cgagaacggc tatcagatcg aggttccgga
     9181 cgagtggctg aaaaacggtt atccctttga gctgcgccgg gcagagtacg ctacagaggt
     9241 aaagttcggc ggctatgtaa agaccgtctg ggagaatgga agaaacaaat tcattcagga
     9301 gggataccgc tccgttatgg cgattcccta tgatatgccg attgtcggct atggcaacaa
     9361 catggttaat actctccgca tctgggacgc gcagccgtta aactccttca gcctccaggc
     9421 ttttgacaag ggagactatc agaaagcagt ggaggaggag aatctggcca agaacctggt
     9481 ggaggttctc tatccgaacg ataaccatta ttccggcaag gaactccgct taaaacagca
     9541 gtatttcttt atctctgcca gcgtacagcg ggctgtggcc aaatataagg agacacacag
     9601 cgatatccat aagctgccgg agaaggtgat tttccagtta aacgataccc atcctacggt
     9661 ggctatcgca gagcttatga gaattctcct ggatgtggaa ggcttagagt gggatgaggc
     9721 gtgggatatc acaaccaagt gctgcgctta cacgaaccat accatcatgt ccgaggccct
     9781 ggagaaatgg cccattgagc tgttttcacg tcttcttccc cgcatctacc agatcgtgga
     9841 ggagattaac cgccgcttct taatcgaggt ggagagacat tatcccggca attacgagaa
     9901 ggtaaagaag atggctatca tctttgacgg ccaggtaaag atggcccatc tggcgattgt
     9961 ggccggcttc tccgtcaacg gcgtggcaag actccacaca gagatcttaa aaaatcagga
    10021 gctgcgggat ttctacgaga tgatgccgga gaagttcaac aacaaaacaa acggcattac
    10081 ccagagacgt ttcctgcttc acggaaatcc ggagctggcc gcctgggtga cagataagat
    10141 tggaagcgag tggatcacag acctgtctaa gattggaaaa ctgaaaatct acgcggacga
    10201 taagaaatgc cagcaggagt ttatgaacat caagtatcat aataagctgc gcctggcaaa
    10261 gtatatcaag gagcacaatg gaatcgacgt ggatccgcga tccatcttcg acgtccaggt
    10321 gaaaaggctt cacgagtaca agagacagct gttaaatatc cttcatatta tgtatctgta
    10381 caaccagctg aaggacaatc cgaacatgga gatggttccg agaaccttta tcttcggagc
    10441 caaggcggcg gcaggctatc agattgccaa gaagaccatc aagctgatta actctgttgc
    10501 caatgtgatc aacaacgacc gctccatcaa tggaaaaatc aaggttgtgt ttatcgagga
    10561 ttaccgcgtc tccaacgcag agctgatttt tgccgcggct gacgtcagcg agcagatttc
    10621 tactgccagc aaggaggcct ccggcacagg aaatatgaaa ttcatgttaa acggcgcgct
    10681 gacgctgggc accatggacg gagccaatgt ggagatcgtg gaggaggtag gacagg
//
LOCUS       DBMDUW010000073        10440 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_3120_length_10440_cov_4.153110, whole genome shotgun sequence.
ACCESSION   DBMDUW010000073 DBMDUW010000000
VERSION     DBMDUW010000073.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 10440)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 10440)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10440
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3120_length_10440_cov_4.153110"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..403
                     /locus_tag="ACZPCR_10935"
     CDS             <1..403
                     /locus_tag="ACZPCR_10935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008397775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF2848 family protein"
                     /protein_id="HIR1231416.1"
                     /translation="GVGSDHTDRELEAVSVPKAKQICAKPICSRIWDYEEIKDHWDEI
                     KLRSWQTIENKEVLYQEGTLKDILPVETILNEMNGRIGAIDNCVIFSGTVPVKNGFCF
                     GSNFRYEMEDKILGRKLSADYNAEAVSEEER"
     gene            403..1923
                     /gene="dctP"
                     /locus_tag="ACZPCR_10940"
     CDS             403..1923
                     /gene="dctP"
                     /locus_tag="ACZPCR_10940"
                     /inference="COORDINATES: protein motif:HMM:NF015445.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein DctP"
                     /protein_id="HIR1231417.1"
                     /translation="MKKGRAGIFCLAAAAMITFLSGCTSSGSSGDKIKLKIATVGNES
                     HQSTIAASVFKEKLEELAGNRFEVTIYPNAQLGGEREMAEGVKIGSIEMAVVTTDGAL
                     PSFVPETQVLAIPYLFADKEEAYFVLDGYLQETLKPEFEEQGFKHLAFCELGFRHFTN
                     NVKEITKAEDMKGLSIRVQESPIWFALAEHLNFIATPISFNELYTALQQGTVDGQENP
                     IASISSSAFDEVQKYMCLDGHTYAPESMIMNLDFYNRLTDEERAWIDEASVYARDTQR
                     QMVTDMEEEMLKAIEDKGVDVCREPDLESFRKATETLYQDSAVTALVSPELTEGVKAA
                     VAQYEAEHGEKGERDMIDKLVDGLARMIMGVSALLVFAITFLQVLCRFVLKSPLPWST
                     DILRLVFTYLVFWGAAWCVREKEHLNVDVVLTALPAGICRWTEILINLILCSFFIFLI
                     YFGIQFCIFGWTQTTSYLPLPMTVYYASIPSAGVAMLYYMVKILIRQIRNNGEGEV"
     gene            1920..3188
                     /locus_tag="ACZPCR_10945"
     CDS             1920..3188
                     /locus_tag="ACZPCR_10945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HIR1231418.1"
                     /translation="MIYIVLLFILFLIGIPICFSLGLVSVFGMVQGATPMIVVIQRLF
                     TGADSTALIAIPLFILAGGLMVQGGISNRIVSFADALIGHFPSGLALVSILACMFFAA
                     ITGSAIAATAAIGGIMIPIMREKNYEDTFSAPLIACGGSIGPIIPPSIPLLLYGTMAN
                     VSVGKLFIGGFIPGIIMGAGLMLYSYMVGKKRRYVGREKRASREEILKTGKDALLALI
                     MPIIIIGGILSGIFTATESGAIACAYAIIIGGFVYKELKWKNMFSLLVDCAKSTGQVL
                     VVVACASLFTWVITVAQVPQTVSALLSESIHSSVLLLLIINIILLIAGTFIDTTSALV
                     IFTPLFLPLVQAMGIDLIHFGLVMAVNLTIGMCTPPLGVCLFVSGSIAKVSLKDQMRD
                     LVPMLGVLLVVLMIITYIPQTVTFLPELLG"
     gene            3542..5518
                     /gene="metG"
                     /locus_tag="ACZPCR_10950"
     CDS             3542..5518
                     /gene="metG"
                     /locus_tag="ACZPCR_10950"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HIR1231419.1"
                     /translation="MCQNCKKPYYITTAIAYTSGKPHIGNTYEIVLADSIARYKREQG
                     YDVRFQTGTDEHGQKIELKAEEAGVTPKEFVDKVAGEIKTIWDLMNTSYDKFIRTTDA
                     DHEAQVQKIFKKLYDQGDIYKGHYEGMYCTPCESFFTESQLVDGKCPDCGRPVQPAKE
                     EAYFFRMSKYAQRLIDYINEHPEFIQPVSRKNEMMNNFLLPGLQDLCVSRTSFKWGIP
                     VSFDPKHVTYVWLDALTNYITGLGYDCDGQNGGLFDKYWPADLHLIGKDIIRFHTIYW
                     PIFLMALDLPLPKQVFGHPWLLQGDGKMSKSKGNVLYADTLVDFFGVDAVRYFVLHEM
                     PFDNDGVITWELMVERMNSDLANILGNLVNRTVSMTNKYFGGVVEKTGAAEDVDADLK
                     AVVLEAVKKADAKMEKLRVADAITEIFGIFRRSNKYIDETTPWTLAKDEEKKARLSEV
                     LYNLTEAITIGASLLSSFMPETSEKILKQLNTEKRSLDQMTEFGLYPSGNKVTDKPEI
                     LFARMDIKEVLEKVEEMKKAEAAAAGEAEEKPEEPGIDIEAKPEITYDDFAKLQFQVG
                     EIISCEEVKKSKKLLCSQVKIGSQVRQILSGIKAWYTPEEMVGKKVMVVTNLKPAKLA
                     GMISEGMILCTEDAEGNVVLMQPEKDVPAGAEIG"
     gene            5875..6108
                     /locus_tag="ACZPCR_10955"
     CDS             5875..6108
                     /locus_tag="ACZPCR_10955"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231420.1"
                     /translation="MKMWQRAAVMTAVSIAMTGIVASGRFQPMFGGVEAGPAVDDRMN
                     EPLGPGLETQAPEETQDPDEPQGPALETEGERE"
     gene            6110..6967
                     /locus_tag="ACZPCR_10960"
     CDS             6110..6967
                     /locus_tag="ACZPCR_10960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003505754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HIR1231421.1"
                     /translation="MFDKKTPAQKEWEAFLKREKKKLGRYGSPRESFWEKRLASLVPD
                     GLSSKLEEAFCKAFQVTLQEGTGLIEKTYSKERLEAEHKVRTYQERLMPTRKHIREHT
                     KSARKQAELATAAAGVQGAGLGLLGIGLPDIPLFLASLLRSLYTLCLSYGIDYRKSGE
                     QELLLEMIELSLYQGEDFFSRDAALNRKLYALAAKDGEKAQTPEKGIPARQKPSPEAV
                     RRASKALSRELLYLKFLQGIPLAGVIGGVYDSIYMGRITKYASLKMERRHLLKLMKNE
                     KKRGKRIDI"
     gene            6957..7721
                     /locus_tag="ACZPCR_10965"
     CDS             6957..7721
                     /locus_tag="ACZPCR_10965"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004536 - DNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HIR1231422.1"
                     /translation="MIFETHAHYDDEAFNEDREAVIKSLAAAGVETVVNIGASMDSSE
                     TTLELTRNYPFIYGTAGVHPSWTDELNEEKFQRLREIIKEPKMVAVGEIGLDYYYKEP
                     PHEIQKKWFERQLDLAREVKLPVVIHSREAAQDTLEIMKAAKAEELGGVIHCFSYGKE
                     MAREYLDMGFFLGVGGVLTFNNSKTLREVVKYVPMDHLVLETDSPYMAPEPNRGKRNT
                     SANLIYVAKMMAEIKGMSPEEVIAATEKNARRLYRM"
     gene            7807..8718
                     /gene="rsmA"
                     /locus_tag="ACZPCR_10970"
     CDS             7807..8718
                     /gene="rsmA"
                     /locus_tag="ACZPCR_10970"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008397789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0000154 - rRNA modification [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HIR1231423.1"
                     /translation="MERRETDVKETENRSTGKLSNPQNTIQVIQKHGFAFQKKFGQNF
                     LIDAHVLDKIIAAAGVTADDMVLEIGPGIGTMTQYLAERARQVTAVEIDTNLIPILKE
                     TLSDYDNVTVINEDILKVDIKKLAEEYNGGKPIKVVANLPYYITTPIIMGLFESGVPI
                     DNITVMVQKEVADRMQVGPGSKDYGALSLAVQYYAEPYIVANVPPNCFIPRPNVGSAV
                     IRLTRHQTPPVEVKDRELMFKLIRASFNQRRKTLLNGLNNSPELSFGKEQIAAAIEQL
                     GVPAAVRGEALTLEQFARLSDLLGGNR"
     gene            9043..9115
                     /locus_tag="ACZPCR_10975"
     tRNA            9043..9115
                     /locus_tag="ACZPCR_10975"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9076..9078,aa:Phe,seq:gaa)
     gene            9137..9207
                     /locus_tag="ACZPCR_10980"
     tRNA            9137..9207
                     /locus_tag="ACZPCR_10980"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9169..9171,aa:Gly,seq:tcc)
     gene            9307..9378
                     /locus_tag="ACZPCR_10985"
     tRNA            9307..9378
                     /locus_tag="ACZPCR_10985"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9339..9341,aa:Gly,seq:gcc)
     gene            9477..10034
                     /locus_tag="ACZPCR_10990"
     CDS             9477..10034
                     /locus_tag="ACZPCR_10990"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024698.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1231424.1"
                     /translation="MLQNKYIQLAPPSLSFAEQAADYYCRNREFLREYEPRREAAFFT
                     AGRQREILEQEIRSQQAKLSFRFYIKPMAEPEKIIGIAALNNVVYGAFCSAFLGYKLD
                     SEYLNRGYMTMAVNMISSYAFQTLGLHRLEANVMPRNKASLRVLEKNQFVNEGISRYY
                     LNINGVWEDHIHMVKLNYGMHNEKH"
BASE COUNT         3017 a         2042 c         2784 g         2597 t
ORIGIN      
        1 tggcgtagga agcgatcata cagatcgtga gctggaggct gtaagtgttc ctaaagcaaa
       61 gcagatctgt gcaaaaccca tttgcagcag gatatgggac tatgaggaaa taaaggatca
      121 ttgggatgag attaagcttc gttcctggca gaccatagag aataaagaag ttttgtatca
      181 agagggaaca ttaaaggata tccttccagt agaaacgatc ttgaatgaga tgaacgggag
      241 aatcggagca attgataatt gtgtgatttt ttcagggaca gttcctgtaa aaaatggttt
      301 ctgttttggc agcaatttta gatatgagat ggaggacaag atattggggc gtaagctgtc
      361 cgcagattat aatgcagaag ctgtgagtga ggaggaaagg taatgaaaaa aggaagggca
      421 ggaatttttt gcttagcggc ggcagccatg atcacgtttc tttctggctg tacaagttca
      481 ggcagttcag gagacaaaat taagcttaaa attgctacag tgggaaatga gtctcatcag
      541 tcaactatag cggcctctgt ttttaaagaa aagctggagg aattggccgg gaatagattt
      601 gaggttacta tttatcccaa tgcgcagcta ggcggagaaa gggagatggc agagggagtc
      661 aagattggat caatagaaat ggctgtcgtt accacagacg gagctcttcc aagttttgtg
      721 ccggaaacac aggttcttgc gatcccctat ctgtttgcgg acaaggaaga agcctatttt
      781 gtactggatg gatatttgca ggaaacatta aaaccggagt ttgaagaaca gggctttaaa
      841 caccttgcct tttgcgagct gggtttccgt cattttacaa ataatgtgaa ggagattaca
      901 aaagcagagg acatgaaagg cttatccatt cgtgtgcagg agtctccaat ctggtttgct
      961 ctggcagaac acttaaattt tattgctact ccgatttcat ttaacgaact ttatacagcg
     1021 ctgcagcagg gaactgtaga tgggcaggag aatccaattg cctctatttc atcttctgct
     1081 tttgatgagg ttcagaaata tatgtgtctg gatggacata cctatgcgcc agaaagcatg
     1141 atcatgaatt tagattttta taaccgtctg acagatgaag agagagcgtg gatagatgaa
     1201 gcgtccgttt atgccagaga tacccagaga caaatggtta cagacatgga agaggaaatg
     1261 cttaaagcga ttgaggataa aggtgtagat gtatgccgcg aaccagattt ggaatccttt
     1321 aggaaagcga cagagactct ttaccaggat tctgctgtga cggctctggt ttcaccggaa
     1381 cttacagaag gagtaaaagc agctgtggca cagtacgaag cagaacatgg tgaaaagggg
     1441 gaaagggaca tgattgataa attggtagac ggacttgcca gaatgattat gggagtgagc
     1501 gctctgctgg tatttgcaat tacattttta caggttttgt gtcgatttgt tctgaagtca
     1561 cctcttccct ggagcaccga tattttgcga ttggtgttta cttatttggt gttttgggga
     1621 gctgcctggt gcgtcaggga gaaggagcat ttaaacgtag atgtggttct tacagctctt
     1681 ccagcaggga tatgcagatg gacagaaatt ttgattaatc tgattttgtg cagttttttt
     1741 atttttctga tttattttgg aattcagttc tgcatttttg gatggacaca gaccacatcc
     1801 tatctgcctc ttcctatgac tgtttattat gcgagtatcc caagtgcagg ggtggcaatg
     1861 ctttactaca tggttaaaat actgatacga cagatcagaa ataatgggga gggagaagta
     1921 tgatctatat tgtcttgcta tttatactgt ttttaattgg aattccaatt tgcttttctc
     1981 tgggactggt atcagtgttt ggaatggttc aaggtgcaac ccctatgatt gtggtgattc
     2041 agagattgtt tactggagct gacagcacag ctttgattgc tatccctttg tttattttgg
     2101 caggaggttt gatggtacag ggcggaattt caaacaggat tgtcagcttt gcagacgctt
     2161 tgatcggaca ttttcccagc ggccttgctt tggtaagtat tctggcatgt atgttttttg
     2221 cagcgattac tggttcagcc attgcagcta cagctgctat tggaggaatt atgattccga
     2281 ttatgagaga aaagaattat gaagatacct tttcagctcc attgattgcc tgcggaggtt
     2341 ctatcggacc tattattcct cctagcattc cgcttttgct ttatggtacg atggctaacg
     2401 taagtgtagg aaagctgttt ataggcggct ttattccagg aatcattatg ggcgcagggc
     2461 tgatgcttta cagttatatg gttggaaaaa aacgccgtta tgtgggaaga gagaaaagag
     2521 ccagccgcga ggaaattttg aaaacaggaa aagatgcgct tcttgcctta attatgccga
     2581 ttattattat tggcggtatt ctatccggca tttttactgc tacagagtct ggagcaatcg
     2641 cctgcgctta tgcgattatt attggtggtt ttgtgtataa agaattaaaa tggaaaaata
     2701 tgttttctct tctggtagac tgtgcaaaat ctacaggaca ggttttggtg gttgtggctt
     2761 gtgcaagctt atttacatgg gtgattacag tagcccaggt tccgcagact gtgagcgcac
     2821 tgctgtcaga gtcgattcac agcagtgtgc ttctcctgct aattattaat attattctgt
     2881 taattgcagg aacatttatt gatacaacaa gcgcattggt tatttttacc cctctgtttc
     2941 tgccgttagt acaggctatg ggaattgatt tgattcattt tggtcttgta atggctgtta
     3001 atctgacgat tggaatgtgt acgcctccgc tgggtgtctg cctatttgtt tctggctcca
     3061 ttgccaaagt cagtctgaag gatcagatgc gagatctggt tcctatgctg ggggtactgc
     3121 tagttgtact gatgattatt acttacattc ctcaaacggt taccttcctt ccagaacttt
     3181 tgggataaaa gaaatttatg agcagataaa atctacagtt ttagtgataa tggcgaggct
     3241 ttcgaagaga ggttcgtgct aatttccgcc accgagcgaa gtgtttgagc cgtaaggcga
     3301 gttttcgcga atggcggatc acagatgcac ggaccgaaca gaaaacacag ccagtcacaa
     3361 aaactgtaga ttttgctata tttatttgta ttgcggctca tatttaatga taatgcattc
     3421 tcagccagcc ctgtttcctc cataaccttt ccttgacaaa acccctgcaa gccgctagac
     3481 ttaaactatt ggtaaaaagg ggaaaaagac cgtttgctat aaattgaagg aggataaata
     3541 catgtgtcag aattgtaaaa agccgtatta tattaccacg gctatcgcct acacatcagg
     3601 caagccgcat atcggcaata cctatgagat tgtgctggca gacagcattg caagatataa
     3661 gagggagcag ggttacgacg tgcgtttcca gacaggaacc gacgagcacg gccagaagat
     3721 cgagttaaag gcagaggagg ccggtgtgac tccgaaggag ttcgtggaca aggtagccgg
     3781 cgagatcaag acaatctggg atttaatgaa tacttcctat gataagttta tccgcaccac
     3841 agacgcagac cacgaggctc aggtccagaa gattttcaag aagctctacg accagggaga
     3901 tatttacaag ggccattacg agggaatgta ctgcactccc tgcgagtcct tctttacaga
     3961 gtcccagctg gtagacggca aatgtcctga ttgcggccgc ccggttcagc cggccaagga
     4021 ggaggcatat ttcttccgta tgagcaagta cgctcagaga ctcattgact atatcaacga
     4081 gcatccagag tttatccagc cggtttccag aaaaaatgag atgatgaaca acttcctgct
     4141 tccaggactt caggatctgt gcgtatccag aacgtccttc aagtggggaa tcccggtttc
     4201 ttttgatccg aagcacgtga cctacgtatg gctggacgcc ctgaccaact atattacagg
     4261 actgggctac gactgcgacg gccagaacgg agggctgttt gacaagtact ggccggcaga
     4321 tttacacctg atcggaaagg acattatccg tttccatacc atttactggc cgattttcct
     4381 gatggccctg gatcttccgc ttccgaagca ggtattcggc catccgtggc tgctgcaggg
     4441 agacggcaag atgagcaaat ccaaaggaaa cgtgctctat gccgatacgc tggtagactt
     4501 tttcggcgtg gacgcagtcc gctactttgt gctccacgaa atgccctttg acaatgacgg
     4561 cgtaatcacg tgggagttaa tggtagagcg catgaactcc gatttagcga acattcttgg
     4621 aaatctggta aaccgtaccg tttccatgac caataagtac ttcggcggcg tggtagagaa
     4681 aacaggcgcg gcagaggatg tggacgcaga cttaaaggca gtagttctgg aagcggtgaa
     4741 gaaggctgac gccaagatgg agaagctccg cgtagctgac gccattacag agattttcgg
     4801 cattttcaga agaagcaata agtacatcga cgagacgact ccgtggactc tggctaagga
     4861 tgaggagaag aaggcccgtc tgtcagaagt tttatacaac ctgacagagg ctatcacgat
     4921 cggcgcgtct cttctttcct ccttcatgcc tgagacctct gagaagatct taaagcagtt
     4981 aaatacagag aagagaagcc tggatcagat gacagaattt ggtctgtatc cgtctggaaa
     5041 taaggtgaca gacaagccgg agatcctctt tgcccgtatg gatatcaagg aagtccttga
     5101 gaaggtggag gagatgaaga aggccgaggc ggcagcagca ggagaggctg aggaaaagcc
     5161 ggaggagccg ggaatcgaca ttgaggcgaa gccggagatc acctacgacg atttcgccaa
     5221 gctgcagttc caggtgggag agattatctc ctgcgaggaa gtaaagaagt ctaaaaagct
     5281 gctctgctcc caagtgaaga tcggaagcca ggtgcgccag attttaagcg gaatcaaggc
     5341 ctggtacacg ccggaggaga tggtgggaaa gaaggtcatg gttgtgacca acttaaagcc
     5401 cgccaagctg gcaggaatga tttcagaggg catgatcctc tgcacagagg acgcggaggg
     5461 caacgtagtc cttatgcagc cggaaaagga cgttccggca ggtgctgaga tcggctaaat
     5521 gaaaaatgaa acagaaggga tgctgcggaa cttttgcagc gtcccttttt tctgcgggat
     5581 agatatggta taataactcc aaaatgcagc tgtgctgcgc acacctgacg ctgcctccgg
     5641 cagctgaaac attttgtcgt taccatatca ggtgaaaaca aatgtctgct ttgcagccgc
     5701 ttgttttcct gctgatatgg tataatatga acacttgacg aggtctttca cgagtttagt
     5761 gagaatatat acctgtccca cttagcaagg tcttgtcgag cttagtgggc atggtataat
     5821 atatagatat gataccggcc agtcagcttc agtacgggaa gaggagggat ccctatgaaa
     5881 atgtggcaga gagcggcagt gatgacggca gtgtccatcg ccatgacggg aatcgtggcg
     5941 tcaggcagat ttcagcccat gtttggaggc gtggaggccg gtccggcagt ggatgacagg
     6001 atgaacgagc ctctggggcc gggattagag acccaggcgc cggaggaaac ccaggatccg
     6061 gacgaacctc agggacctgc gctggaaact gaaggagaaa gagaatagaa tgttcgataa
     6121 gaaaacgccg gcccagaagg aatgggaggc attcttaaaa cgtgagaaaa agaaactggg
     6181 aagatatgga agccccaggg agtcattctg ggaaaagcgt cttgcttccc tggttccaga
     6241 cggcctgtcc tcaaagctgg aggaggcgtt ttgcaaagca tttcaggtga cgcttcagga
     6301 agggacaggg ctgatagaga aaacctattc caaggaaagg ctggaggcag aacataaggt
     6361 gagaacctat caggaacggc ttatgcctac cagaaagcac atcagagaac atactaaaag
     6421 cgccagaaag caggcggagc ttgccacggc ggcagcagga gttcagggcg caggtctggg
     6481 acttttaggg attggccttc cggatatccc gctgtttctt gcctctctgc ttcgaagcct
     6541 ttatacactc tgtctttcct atggaattga ttacaggaag tccggagaac aggaacttct
     6601 cctggaaatg atagaacttt ccctgtatca gggagaggat tttttcagcc gtgatgcggc
     6661 cttaaacaga aaattatacg cgctggcggc aaaggatggt gaaaaggctc agacaccaga
     6721 aaaagggata cctgccagac agaagccatc tccggaagca gtccggagag cgtccaaagc
     6781 cctgtccaga gaacttctgt atctgaaatt tctgcaaggc attccccttg caggggtgat
     6841 aggaggcgtc tatgacagca tttacatggg aagaatcaca aaatatgctt ctctgaaaat
     6901 ggaacggcgt catttactga aactgatgaa aaatgaaaag aaaagaggaa aaagaattga
     6961 tatttgaaac acatgcacac tacgatgacg aggcattcaa tgaagacaga gaggcggtaa
     7021 ttaaaagtct tgcagctgca ggagtggaaa ccgttgtcaa tataggagcc agcatggaca
     7081 gctctgagac aaccctggag ctgaccagaa attatccgtt tatctatggt acagctggtg
     7141 ttcatcccag ctggacagat gaactgaatg aggagaaatt ccagagactg agagaaatta
     7201 taaaggagcc taaaatggtg gcagtgggag aaattggcct tgactactac tataaagagc
     7261 cgccccatga gattcagaag aagtggtttg agcgccagct ggatcttgcc agagaggtaa
     7321 agctgccagt ggttattcac agcagggagg cagctcagga tacgctggaa atcatgaagg
     7381 cggccaaagc agaagagctg ggaggagtta ttcactgctt ctcttatgga aaagaaatgg
     7441 caagggaata tctggatatg ggatttttcc tgggagtcgg cggcgtttta acctttaata
     7501 attcaaagac gctccgggaa gtggtaaaat atgttccgat ggatcatctg gttctggaaa
     7561 cagacagccc gtatatggct ccagagccaa atcggggaaa acgcaatact tctgcgaacc
     7621 tgatttatgt ggcaaagatg atggcagaaa ttaaaggcat gtctccggaa gaggtaattg
     7681 cggctacaga aaagaacgca agacgtctct acagaatgta acattacgca ggaaaataga
     7741 agcagtcaga aaacagccgg ataagcagga aggaatgctg tccggctgag aagagtggag
     7801 tggcagatgg agcgaagaga aactgacgtc aaagaaacag aaaacagaag cacagggaag
     7861 ctgagcaatc cccagaatac cattcaggtg attcagaagc atggatttgc gttccagaaa
     7921 aagttcggac agaacttttt gattgacgcc catgtgctgg acaagattat tgcagcagca
     7981 ggggtgacag ctgatgatat ggtactggaa atcggtcctg gaatcggaac catgacccag
     8041 tatctggcag agcgggccag acaggtgaca gctgtagaga tcgatacgaa tttaataccg
     8101 attttaaagg aaacgttatc agactatgac aatgttacgg ttattaatga ggacattctg
     8161 aaagttgaca taaaaaaact ggcggaggag tataacggag gaaagcccat caaggtggtg
     8221 gccaatctgc cctattacat caccacgccg attatcatgg gactgttcga gagcggagtt
     8281 cccattgaca atattacggt tatggttcag aaggaagtgg cggaccggat gcaggtaggg
     8341 ccgggatcca aggattacgg cgctctttcc ctggcggttc agtattatgc agagccgtat
     8401 attgtagcca atgtgcctcc gaactgcttc attccgcggc ctaacgtggg atctgcagtg
     8461 atccggctga ccaggcacca gacgccgcca gtggaggtaa aggacagaga gctgatgttt
     8521 aagctcatcc gggcgtcctt caatcagaga agaaagactc tcttaaacgg tctgaataat
     8581 tctccagagc tttccttcgg aaaagagcag atcgcggctg ccattgagca gctgggggtt
     8641 ccggcggcag tcaggggaga ggctcttacc ctggagcagt tcgcccgcct gtcagatctt
     8701 ctgggtggga acagataaaa aatagcgtca gtgtactcag tgcaaattga cgctggggac
     8761 agagcgcaga gaaaacagac aggaaaatac ccgcatgggc agaagttcag ccatatacag
     8821 aacctgacag aaaaaatggc gaaaccgcgt tttggccaaa gctttctgcc gggttctgta
     8881 tggggcggat atatggtgcc tttgtctgct ttgcacggac aaaaaggcgt aaggatggac
     8941 ggctgtatat ccggagaaaa aaatttagaa aagacttgac aaattgaaaa atatccggta
     9001 aaataatccc tgtcgtcacg gaagagaagt cttcagaacg atgcccagat agctcagttg
     9061 gtagagcaga ggactgaaaa tcctcgtgtc actggttcga ttccggttct gggcatttga
     9121 atttcataat tcatacgcgg gtgtagttca atggtagaac accagccttc caagctggat
     9181 acgtgggttc gattcccatc acccgctttg caagaaatac cttgcaaagt agaaagctct
     9241 gtgttataat ataacatgtc agcagttcaa atattttaat aagatatcag tttatctgat
     9301 aaatgtgcgc gagtggctca gtggtggagt atcgccttgc caaggcgagg gtcgcgggtt
     9361 cgaatcccgt ctcgcgctct tttatttttg tcggaacctt tgttttgcag aggattccgg
     9421 cttttttgtt tttgaaaatt tttataggaa aatgcttagc agaaggagaa tgtataatgc
     9481 ttcagaataa gtatatacag ctggcgcctc cgtctttgtc tttcgcagag caggcggcgg
     9541 actattactg caggaacaga gaatttttaa gggaatatga gccgaggaga gaagccgcct
     9601 tttttacagc ggggcgtcag cgggagattc tggaacagga aatccgcagc cagcaggcaa
     9661 agctgtcttt ccgtttctat ataaagccga tggcagagcc ggaaaagatc ataggaatcg
     9721 cagccctaaa taacgtggtg tacggcgcgt tctgctcagc ctttttaggg tacaagctgg
     9781 acagcgaata tttaaacagg ggctatatga ccatggcggt aaacatgata tcctcctatg
     9841 ctttccagac tctgggcctg caccgtctgg aggccaatgt gatgcccagg aataaagcct
     9901 ccctgagagt gctggagaag aatcagtttg tcaatgaagg aatttccagg tactatctca
     9961 atatcaacgg cgtttgggag gatcatatcc atatggtgaa gctgaattat gggatgcata
    10021 acgaaaagca ttaaaagacg tttttatata gggaaaagat actgccccaa tccctgggaa
    10081 aaacgtggaa aacaagaaag tacaaaaaaa ctgaaaaaac ttaaaaaagt gcttgacggt
    10141 gtcgaaaacc tgtgatatta taatacgcgt cgctgagagc ggcacggaag ttcgaaagaa
    10201 cttcaaaaaa taaatgaaaa aagttgttga caaacacgat gagttgtgat aagataaacg
    10261 agttgctgtt gagaaacaac aacgaacctt gaaaactgaa cagtatgtaa aaccctgaaa
    10321 attctaagaa caaaaggcgc aggagccttg aagttcgaga gaacattcag aacaacctaa
    10381 aaacagtaaa acggtttaaa aattagccaa gctaagtttt ggactggaat caaaacttta
//
LOCUS       DBMDUW010000074         9780 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_3315_length_9780_cov_2.568137, whole genome shotgun sequence.
ACCESSION   DBMDUW010000074 DBMDUW010000000
VERSION     DBMDUW010000074.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 9780)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 9780)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9780
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3315_length_9780_cov_2.568137"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..229
                     /locus_tag="ACZPCR_10995"
     CDS             <1..229
                     /locus_tag="ACZPCR_10995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HIR1231425.1"
                     /translation="RIILPTVEEAKKFVAAASRCDFDIDVFYNRIVIDAKSLLGVLSL
                     DLTRVLTVEYNGENEEFEAFLAEKAAAETAA"
     gene            363..2759
                     /locus_tag="ACZPCR_11000"
     CDS             363..2759
                     /locus_tag="ACZPCR_11000"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006772971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HIR1231426.1"
                     /translation="MGMIHEADDSRRRVKISVRNLVEFVLRSGDIDNRRTAGAQKEAM
                     QEGTRIHRKIQRQQGPSYRAEVFLRHQVEEEGFLLIIEGRADGIIEEPSGVTIDEIKG
                     VYLDVNEMKEPNPVHLAQAMCYAWFYVSEHNLPEAAVQMTYCSLETEEIRRFKTVKTA
                     QELEGWFQGLLHEYMKWARYLYHNAVRRDESLRELQFPFAYRNGQRDLAVSVYRTVSR
                     GRKLFIQAPTGIGKTLSAMFPSLKAIGEGYGDKLFYLTAKTITRSVAEETLEILRNRG
                     LYFRSVTITAKEKLCFLEKPECNPDACPHAKGHFDRVNDAVYTAVHQEFGITRETILS
                     YAEQFQVCPFELCLDISSFVDGIICDYNYVFDPDVRLKRYFSESQRGDYIFLIDEAHN
                     LAGRAREMYSASIIKEDFLEIKKLIKETSPRLTRYLNRVNRLLLEMKRECEGIEILSD
                     VGPLVMALSSAFSELEKFLDQYREFKDREAALELYFSVRSFLSIYERTDEHYRIYSRL
                     LENGNFCVKLLCVNPIQNLAECLSQGRAAVFFSATMLPIRYYRELLSNEPEDYAVYVN
                     SPFPEKNRAILVSSDLSSRYTRRNRREFEKAADYIEEIASAKMGNYMVFFPSYQYMEA
                     VREILQERNSELFLLVQESRMTEADREAFLAEFSVKREESLAALCVMGGIFSEGIDLT
                     GDQLIGVLIIGTGLPQVNPEQEILKQYFAENGEDGFDYAYRYPGMNKVLQAAGRVIRT
                     MEDRGIIALLDDRFLQPEYQALFPREWREYFIVTRQNVRQAVEAFWASSESGKEEKRQ
                     "
     gene            complement(2760..3668)
                     /locus_tag="ACZPCR_11005"
     CDS             complement(2760..3668)
                     /locus_tag="ACZPCR_11005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008374739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HIR1231427.1"
                     /translation="MDINYELYKVFYHVASTLSFSEASKQLFISQSAVSQSIKVLEKK
                     LNQTLFIRSTKRVQLTPEGEILLKHIEPAMNLIKKGENQLLEANTLNGGQLRIGASDT
                     ICRYFLVPFLSHFHSLYPNIHIKVTNRTSIECARLLENGQVDFIITNYPNSALSNTQN
                     IKMLRPFHDVFAANEAFFPLKGRKMSLEELQTYPILMLDKKSTTSEFLHSMFQKHQLD
                     LVPEIELSSNDLLIDLAKIGLGIAFVPDFCIPSSEKDLFILNLEEELPERQLVVVHNE
                     NIPVSQAARQFMELLGAKENEKKGQL"
     gene            3842..4396
                     /locus_tag="ACZPCR_11010"
     CDS             3842..4396
                     /locus_tag="ACZPCR_11010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 domain-containing protein"
                     /protein_id="HIR1231428.1"
                     /translation="MERRTNEHEETREFDHTDFYQMYQDEMDCIVPCTAQEMEELSEE
                     LLNGSETARKRLVEGCLFLAAEIAEEYQNKGLSAGDLVQEANMALLILASEYEGGSFR
                     AQVEERIREALEEALELQDTECRIEEEMLARVNVLKDISASIAEELGREATVEELAAR
                     LKMTEEEIKDIMKLTLDAMSVSGE"
     gene            4407..5042
                     /locus_tag="ACZPCR_11015"
     CDS             4407..5042
                     /locus_tag="ACZPCR_11015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003510661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HIR1231429.1"
                     /translation="MKLYLIRHGQTLWNQEGKIQGKTDIPLNDEGRKQAGLLAEAMEN
                     RPVGAVYSSPLKRAFETASCVAEQKGLSVVSLDGLREVDFGLWEGMTWKEIEKNYHED
                     FVLWDKNPAEHTPTGGEKREDCAARCAKAMEQILAKTPAGQDAAVVAHGGILVFAALW
                     LTRKSQEKNEIIVKNASITTIEYDRESGTGTILCLNDVSHLGRHCSGEGII"
     gene            5189..8953
                     /locus_tag="ACZPCR_11020"
     CDS             5189..8953
                     /locus_tag="ACZPCR_11020"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HIR1231430.1"
                     /translation="MSVRRIFVEKREAFAVKAKELREEIVNYLGIQTITGVRVLIRYD
                     IENVSDAVYQEALATIFSEPPMDDVYEESFETAEGDLVFTVEYLPGQFDQRADSAEQC
                     VKLLSEEEEPVIRSATTYVVSGTLTEEEKAAVKSLCINPVDSRENNNPKPETLVTVFE
                     QPEDVKIFDGFMDMPEKELNELYSSLNLAMTFKDFLHIQNYFKNEEKRDPSVTEIRVL
                     DTYWSDHCRHTTFQTELKDVEFTKGDYNEPIENTYRQYLADREEVYAGRSDKYVCLMD
                     LALMAMKKLRKEGKLQDMEVSEEINACSIVVPVVIDGQEEEWLVNFKNETHNHPTEIE
                     PFGGAATCLGGAIRDPLSGRTYVYQAMRVTGAADPTRPMSETMHGKLPQRQIVTDAAH
                     GYSSYGNQIGLATGYVKELYHPNYAAKRMEIGAVMAAAPRKNVIRETSDPGDVIILMG
                     GRTGRDGIGGATGSSKVHTEESIEVCGAEVQKGNPPTERKLQRLFRRPEVSRLIKKCN
                     DFGAGGVSVAIGELAAGLEIDLDKVPKKYAGLDGTEIAISESQERMAVVVDKKDVDQM
                     MDYVAEENLEAVPVAVVTESPRLVMRWRGRTIVDISRAFLDTNGAHQEAAVTVEIPAK
                     EGNLFERKEIGDVKEQWLKLLSSLNVCSQKGLVEMFDASIGAGSTYMPYGGRYQLTET
                     QAMIAKLPVLKGKCDAVTMMSYGFDPYLSSWSPYHGAVYAVLDSVAKIVANGGDFRKI
                     RFTFQEYFKRMTEDRTRWGAPFCALLGAYSAQMGFGLPSIGGKDSMSGTFNDETHGEI
                     NVPPTLVSFAVDVSDKQHVVTPEFKKAGSKIVVLKIARDAYDLPVYSQVMDSYKKLYK
                     DMEAGNVISAYAVEAGGIAEAVSKMAFGNKLGVKIEHSVDPRDFFVPAWGDMVCEVPD
                     GKLGSLGITYTVIGEVTDKAAFEYGSVSISMDEALNAWTKTLEDVFPTESKVDQKPVR
                     TELYNTDKVYVCKHKVTQPTVFIPVFPGTNCEYDSTKAFERAGANVITKIFRNRDAAD
                     IRDSVEVYRKAIAQSQIVMFPGGFSGGDEPDGSAKFFATTFRNAVLKEELEKLVNERD
                     GLILGVCNGFQALIKLGLLPEGRITELKKDSPTLAMNTIGRHISKMVNLKVVSNKSPW
                     LREAELGGIYVNPISHGEGRFVASEEWLDKLYANGQVATQYADAEGNPTMDEMWNPNG
                     SAMAIEGITSEDGRIYGKMGHSERIGDGVFMNIYGDKDIKIFESGVKYFK"
BASE COUNT         2696 a         2041 c         2740 g         2303 t
ORIGIN      
        1 gcggattata ttaccaaccg ttgaggaggc taagaaattt gtggcggcag catcaagatg
       61 tgacttcgat attgatgtat tttataatcg cattgtcatt gatgcaaaat ctcttttagg
      121 agtgttaagc ctggatttaa cgagagttct caccgttgaa tacaatgggg agaatgaaga
      181 gtttgaagct tttctggctg agaaggctgc tgccgagaca gccgcttaat ggtatgtact
      241 tatttaaagg aaggaaactg cgaagaggcg gtttcctttt tttagttcat gggaacgtcc
      301 tgtgaaagga tatcctatga aaggaaagga atttcgcaga ggccgcgtgg gggaggaaaa
      361 agatggggat gatacatgag gcagatgaca gccgccgcag ggtgaaaata tctgtgcgaa
      421 atctggtgga atttgtgctg cgctccggcg atatcgacaa tcggagaacg gcaggagctc
      481 aaaaggaggc catgcaggag ggaacaagaa ttcatcgaaa gattcaaagg cagcaaggcc
      541 cctcctaccg ggctgaggtt tttctgagac accaggtgga ggaagaggga tttcttctta
      601 taatagaagg gagagccgac ggcattatag aggaaccctc cggcgtgacc attgacgaga
      661 ttaagggcgt gtacctggat gtaaacgaaa tgaaggagcc aaatcctgtc catttggccc
      721 aggccatgtg ctatgcctgg ttttacgtat cggaacacaa cctgcctgag gcggcggttc
      781 agatgaccta ctgcagtctg gagacagaag agatccgaag gttcaaaaca gtaaaaacag
      841 cccaggaact ggaaggctgg tttcagggac ttctccacga atacatgaaa tgggccagat
      901 atctgtacca taacgcagtc cggcgggacg aatctctgag ggagctgcag tttccctttg
      961 cctacagaaa tggccagaga gatttggcgg tatctgtgta ccggacagtc agcaggggaa
     1021 ggaaactgtt cattcaggcg cccacaggaa ttgggaagac tctttctgcc atgtttccaa
     1081 gcctgaaggc gataggagag ggatatgggg acaagctgtt ttatctgacg gctaagacga
     1141 tcacccgctc agtggcggag gagacgctgg aaattttgag gaacagaggc ctgtattttc
     1201 gttctgtcac tatcacggcc aaggaaaagc tctgctttct ggaaaagccg gagtgcaatc
     1261 cggacgcctg tccccatgca aaagggcatt tcgaccgggt caacgacgca gtctatacgg
     1321 ctgtccatca ggagttcggc attaccaggg aaacgatttt atcttatgca gaacagtttc
     1381 aggtctgtcc ctttgagctg tgccttgata tcagcagctt tgtggacgga attatctgcg
     1441 attacaatta tgtgtttgat ccggacgtac ggctgaaacg gtatttttca gagagccaga
     1501 gaggagatta tatttttttg atcgatgaag cccacaacct ggcagggcgg gccagggaaa
     1561 tgtacagcgc ttctattata aaggaagatt ttctggagat aaaaaagctg ataaaggaga
     1621 cctcaccccg gctgacacgt tatctgaacc gggtcaaccg gctgcttctg gagatgaagc
     1681 gggaatgtga ggggatcgaa atactctctg atgtggggcc tcttgtgatg gcgctgtcca
     1741 gtgctttttc tgaattagag aaattcttag atcaatatcg cgaattcaaa gacagagagg
     1801 cggcgctgga gctttatttt tctgtcagga gttttttgag tatctatgaa aggacagacg
     1861 agcactaccg gatctattcc agacttttgg aaaatggaaa tttctgtgtg aagcttctct
     1921 gtgtgaaccc aatccagaat ctggcagagt gcctgagcca ggggagagcg gctgtctttt
     1981 tttctgccac catgcttcct atccgttact acagagagct tctaagcaat gagccggagg
     2041 attacgccgt ttatgtgaat tcgccgtttc cggagaaaaa cagggcgatt cttgtctcct
     2101 ctgatctcag cagccggtat accagaagaa acagacggga gtttgaaaag gcggcggatt
     2161 atattgagga gattgcctcg gcaaagatgg gaaattatat ggtgttcttc ccctcttacc
     2221 agtatatgga agcggtaagg gagattcttc aggaaagaaa ctcagagctg tttctgctcg
     2281 ttcaggaaag ccgcatgacg gaagcggaca gagaagcgtt tctggcagag ttttctgtta
     2341 aacgagagga aagcctggcg gctctctgcg ttatgggagg cattttttcg gagggaattg
     2401 atttgacagg ggatcagctg ataggcgttc tgattatcgg gacagggctt cctcaggtga
     2461 atccggagca ggaaatttta aaacagtatt ttgcggaaaa tggggaagac ggttttgact
     2521 atgcctaccg ctatccaggt atgaacaagg tgctgcaggc agcggggcgg gtgatccgca
     2581 ccatggaaga ccggggaatc attgccctgt tagacgaccg ttttctgcag ccggaatatc
     2641 aggcgctgtt ccccagggaa tggagagaat actttatcgt tacaaggcag aatgtcaggc
     2701 aggccgtgga ggccttctgg gcttcgtcag aatccggcaa agaagaaaag aggcagtgat
     2761 tacagctgcc cctttttttc gttctccttt gcccctaaaa gctccataaa ctgtctggca
     2821 gcctgggaga cgggaatatt ttcattgtga accaccacca gctggcgttc cggcagttct
     2881 tcctccagat ttaagataaa cagatctttc tcggaggaag gaatgcagaa gtccgggaca
     2941 aaggcaatgc ccagaccgat tttagccaga tcgatcagaa ggtcattgct gctcagctcg
     3001 atttccggaa ccagatccag ctgatgcttc tgaaacatac tgtggagaaa ttcgctggtc
     3061 gtgctctttt tatctaacat cagaatcgga taggtctgaa gctcctccag actcatcttt
     3121 ctgcccttta atgggaaaaa cgcttcgttt gctgcgaaca cgtcgtggaa gggccgcagc
     3181 atcttgatat tctgggtgtt ggagagcgcg gaattcggat aattggtgat gataaaatcg
     3241 acctggccgt tttccagcag cctggcgcat tcaatcgagg tgcggtttgt caccttaata
     3301 tgaatattgg ggtagaggct gtgaaaatgg cttaaaaacg gcacgaggaa atagcggcag
     3361 atggtgtcgc tggcgccgat tctcagctgg cctccgttca gcgtgttggc ctccagcagc
     3421 tgattttctc cttttttaat cagattcatg gcaggctcga tgtgctttaa gagaatttct
     3481 ccctccggcg tcagctgcac ccgctttgtg cttctgataa acagagtctg gttcagcttt
     3541 ttttccagca ccttgataga ctggctgact gctgactggg agatgaaaag ctgcttcgag
     3601 gcctcggaaa agctcagcgt ggaggccaca tggtaaaata ccttgtataa ttcatagttt
     3661 atatccatca ttagatctcc ttataaaaga tactgcttat tttagcacag acggaggtat
     3721 tttgcaaatt tcttttcttc ctattatatc cagggcatgg tataatagga acacttgacg
     3781 aggtttttca cgagtctagt gggcatggta tactttatta taaaaacagg aggacatgac
     3841 gatggaacgc agaacaaatg agcatgaaga gacgagagaa tttgaccata cagattttta
     3901 ccagatgtac caggacgaga tggactgtat cgtgccctgc acggcccagg agatggagga
     3961 gctgtcggag gagcttttaa atggaagcga gacggcgaga aagcgcctgg tggagggatg
     4021 cctttttctg gctgccgaga ttgcagagga gtaccagaat aaaggacttt cagccgggga
     4081 tctggtgcag gaggccaata tggctcttct gattctggcc tctgagtacg agggaggcag
     4141 tttccgggct caggtggagg agcggatccg cgaggcgttg gaggaggctc tggagcttca
     4201 ggacacagaa tgccggattg aggaggaaat gttagccaga gtcaacgtgt taaaggatat
     4261 ttctgccagc atagcggagg agctgggacg ggaggccacg gtggaagaac tggcggcccg
     4321 cctgaagatg acggaagagg aaatcaagga tatcatgaag ctgacgctgg acgctatgag
     4381 tgtcagcggc gaataggagg aagggtatga agctgtatct gatccgccac ggacagactc
     4441 tgtggaacca ggaggggaag attcagggaa agacagatat tcctttaaat gacgaaggga
     4501 gaaagcaggc cggactgctg gctgaggcca tggagaaccg gccggtggga gctgtgtatt
     4561 ccagtcctct aaaaagagcc tttgagactg cctcctgcgt cgcagaacaa aagggactgt
     4621 ctgtcgtgtc tctggatgga ctcagagagg tggattttgg tctctgggag ggcatgacct
     4681 ggaaggagat agagaaaaac tatcatgagg attttgtcct ctgggataag aatcctgcag
     4741 agcacacgcc tacaggggga gagaaaagag aggactgcgc cgccagatgc gcgaaagcca
     4801 tggagcagat tttagccaag actccggcag gccaggacgc ggcggttgta gcccacggag
     4861 ggattcttgt ctttgccgcg ctgtggctga cgcgaaagag ccaggaaaaa aatgagatta
     4921 ttgttaaaaa tgcaagcatt acaaccattg aatacgacag agagtcaggg acgggaacga
     4981 ttctgtgcct gaatgatgta agccatctgg gccgccactg ctccggggaa ggaatcatat
     5041 aaggggtatt gattagcata tttgataata tctattaaat atattaattt tacttattta
     5101 tattttttgt ttatgatagg ttcaggaaag aaactatgaa ccataaggaa catatgtgat
     5161 agaaatgcga tctgtaagga ggaacgtcat gagcgtaagg cgtatttttg ttgagaagag
     5221 agaggcattt gctgtgaagg caaaggagct cagagaggag attgtaaatt atctgggcat
     5281 tcagaccatt acaggcgtca gagttctgat ccgctatgat attgagaacg tttctgacgc
     5341 tgtctaccag gaagctctgg ctacgatttt ttccgagcct ccgatggacg acgtgtatga
     5401 ggagagcttc gagacagcgg agggagatct ggtatttaca gtagagtacc ttccgggaca
     5461 gtttgatcag agagccgatt ctgccgagca gtgcgtgaag cttctcagcg aggaggagga
     5521 gccggtgatc cgttctgcta ctacgtatgt ggtatcagga acccttacag aggaggagaa
     5581 ggcagctgtc aaatctctct gcattaatcc ggtagattcc agagaaaata acaatccgaa
     5641 gccagagaca ctggtgacag tgtttgagca gccagaggat gtaaagattt ttgatggctt
     5701 tatggatatg ccggagaagg aactgaacga gctgtacagc tccttaaatc tggctatgac
     5761 tttcaaggat ttcctgcaca ttcagaatta ttttaagaat gaggagaaga gagatccgtc
     5821 tgtaacagaa atccgcgtac tcgatactta ctggtctgat cactgccgcc atacgacctt
     5881 ccagacagag cttaaagatg tagagtttac aaagggcgat tacaatgagc cgattgaaaa
     5941 cacttacaga cagtatctgg ctgaccgcga ggaggtttat gccggaagaa gcgataaata
     6001 tgtctgcctg atggatttag ccttaatggc aatgaagaag ctgagaaaag aaggaaagct
     6061 ccaggatatg gaggtttctg aggagatcaa cgcctgcagc atcgtagttc ccgttgtcat
     6121 cgacggacag gaagaggagt ggctggtaaa ctttaagaac gagactcaca accatccgac
     6181 tgagattgag cctttcggag gcgcagctac ctgtctggga ggagccatcc gcgatccgct
     6241 ttccggacgt acttacgtat atcaggccat gcgcgtgaca ggagcggcag atccgacccg
     6301 ccccatgtca gagactatgc acggaaagct gcctcagaga cagattgtaa cagacgcagc
     6361 ccacggctac agctcctacg gaaaccagat tggactggcc acaggatatg taaaggagct
     6421 ttaccatcca aactatgcgg ctaagagaat ggagatcgga gccgttatgg cagccgctcc
     6481 cagaaagaac gtaatccgcg agacctctga tccaggcgac gtaatcatcc tcatgggagg
     6541 aagaacggga cgcgacggta tcggcggagc taccggttcc tccaaggttc acacagagga
     6601 gtctatcgag gtgtgcggcg ctgaggttca gaagggaaat ccgcctacag agagaaagct
     6661 tcagagatta ttccgccgtc cggaggtgag ccgtctcatc aagaagtgca acgatttcgg
     6721 cgcaggcggc gtttccgttg ctatcggcga gctggcagca ggccttgaga ttgatctgga
     6781 caaggttccg aagaaatatg caggccttga cggcacagag attgccattt ctgagtccca
     6841 ggagagaatg gcggtagtag ttgacaaaaa agatgtggat cagatgatgg attatgtggc
     6901 agaggaaaat ctggaggcag ttccagttgc cgttgtcaca gaatctccaa gacttgttat
     6961 gcgctggaga ggcaggacca tcgtagatat aagccgtgct ttcttagata caaacggcgc
     7021 tcaccaggag gcagccgtaa cagtggagat tcctgcaaaa gagggcaatc tcttcgagag
     7081 aaaagagatt ggcgatgtga aggagcagtg gctgaagctg ttatccagct taaatgtgtg
     7141 ctcccagaag ggacttgtgg agatgtttga cgcctccatc ggagcgggaa gcacctacat
     7201 gccttacggc ggccgctatc agctgacaga gactcaggcc atgattgcca agctccctgt
     7261 attaaagggc aaatgtgacg ctgttaccat gatgagctac ggctttgatc cgtacctgtc
     7321 cagctggagc ccataccatg gagctgtcta cgcagtactt gattccgtag ccaagattgt
     7381 ggctaatgga ggtgatttca gaaagatccg ctttaccttc caggagtact ttaagaggat
     7441 gacagaggac agaacaagat ggggcgctcc gttctgtgca ctcttaggag cttacagcgc
     7501 tcagatgggc tttggacttc cttccattgg aggaaaggac agtatgtctg gaaccttcaa
     7561 cgatgagact catggagaaa tcaacgtacc gccgacactg gtatccttcg ctgtggacgt
     7621 ttctgacaag cagcatgtgg taacgcctga gttcaagaaa gcgggcagca agattgtcgt
     7681 attaaagatt gcaagagacg cttacgatct gccggtttac agccaggtga tggacagcta
     7741 caagaagctc tataaagata tggaggctgg aaacgtcatt tccgcatatg cagtagaggc
     7801 tggcggaatt gccgaggcag tgagcaagat ggccttcgga aacaagctgg gcgtgaagat
     7861 tgagcacagc gtagatccga gagacttctt cgttccggca tggggcgata tggtctgcga
     7921 ggtaccggac ggaaagctgg gaagccttgg aattacctat acagtaatcg gtgaggtgac
     7981 agataaggca gcctttgagt acggcagcgt atccatctcc atggatgagg ctttaaacgc
     8041 ctggacaaag acgctggagg acgtattccc gaccgagtcc aaggtagatc agaagccggt
     8101 gagaacagag ctttacaata cagacaaggt ttatgtatgt aagcacaaag taacccagcc
     8161 gacagtattc atccctgtat tcccgggaac caactgcgag tacgacagca ctaaggcctt
     8221 tgagcgggca ggcgccaacg ttatcacaaa gattttcaga aacagagacg cggcggacat
     8281 cagagattcg gtagaggttt acagaaaggc cattgcccag tcccagatcg tcatgttccc
     8341 aggcggcttc tccggcggag acgagccgga cggttctgcc aaattctttg ccacaacttt
     8401 cagaaacgca gttctgaagg aggagctgga gaagctggtt aacgagagag atggactgat
     8461 tctcggcgtg tgcaacggat ttcaggccct gatcaagctg ggactgctgc cggagggaag
     8521 aatcactgag cttaaaaagg attccccgac gctggctatg aacaccatcg gacgccatat
     8581 ttccaagatg gtcaatctga aggtagtttc caacaagtcc ccgtggcttc gcgaggcaga
     8641 gctgggcgga atctatgtga acccgatttc ccacggcgag ggacgcttcg tggcaagcga
     8701 agaatggctg gataagctct atgcaaacgg ccaggtagct acacagtacg cagacgcaga
     8761 gggcaatccg accatggacg agatgtggaa tccaaacggt tccgctatgg ctatcgaggg
     8821 aattaccagc gaggacggcc gtatctacgg aaagatgggc cattccgaga gaatcggaga
     8881 cggcgtattt atgaatatct acggagacaa agacattaaa atctttgaat ctggagtaaa
     8941 atacttcaag taaaacaggt cctgtgcagg tgaaaaataa gaacgtaaaa aagtgcagtt
     9001 aaaaatcgac tgcgcccgcg actgtagcag tagctgcaaa tgcgacgttc atttcaggga
     9061 atccggctgc acctgcagcc gtgactgcac tgcgaataaa aaagatcaac ttagacaatc
     9121 agtctgggct gatctttttc tgtatttcat tatcggtata tcggttgcgt ctgcggctaa
     9181 tttgccaaag cagtttcagg aatattctga agaaatctct aaagtgttca atggaaatgt
     9241 atcattcact gcgacagttg cctttaaagc ggattttgtc cgcttttttg tttttcatta
     9301 aaaagcaacc cacttctgtc atactaagta tagcaagcga aaaaagagaa caagcttatg
     9361 agatattata tctcagactg ccatttatcc gtggaaaacc atttacagtg gttccaaact
     9421 ccattaaaaa tggagtcgca gagtagtcag gaaatgaata gtgtactata gtgcaacgta
     9481 gtacgcgcaa cctgctatta ggcagagtat ttatggccac catgtatcca cacacctaaa
     9541 gatatgtggt tttacggctg gctatttata aaaaaaacat aaaatcgtaa aaaacaagtt
     9601 gataatttcc caaattctga gtataataaa aataccaaga aagaaatttc ttcctagaga
     9661 taggacacga agcataagga gtttgcttcc gttgcactgg caacgtaaaa actttgcatt
     9721 tactcttaag catagaggat aatcaagccg agcgggtgag aagcctgtga tttggtggca
//
LOCUS       DBMDUW010000075         9602 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_3376_length_9602_cov_5.532049, whole genome shotgun sequence.
ACCESSION   DBMDUW010000075 DBMDUW010000000
VERSION     DBMDUW010000075.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 9602)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 9602)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9602
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3376_length_9602_cov_5.532049"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            212..1081
                     /locus_tag="ACZPCR_11025"
     CDS             212..1081
                     /locus_tag="ACZPCR_11025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003509518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HIR1231431.1"
                     /translation="MENNIIDKIIQIKDVLPKKQRTLCNYLVINYVEAGMMTVAELAQ
                     KSGVGTTTVMRLIKTLGYENYSDFKHELLNLSLMRTSTSYRGVKQSFKSAAQSSESNL
                     LNHLWMETNHTIENIITPKNAQQIEKAVDLMLSASAVYFLGLRSSRAAAYYLEDTISR
                     FYPKTRQLSHEPDFLYDRILRMPADSALVVFSIWPCTKTTIEAADLAHQNGVPVILIT
                     NTLLNPIARYAEVVIDTNSVNSGCGNMAIMFAAEAVIAEMGRKTEPSSTEALETLERQ
                     LDPLDIFIRERTI"
     gene            1150..2001
                     /locus_tag="ACZPCR_11030"
     CDS             1150..2001
                     /locus_tag="ACZPCR_11030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6282 family protein"
                     /protein_id="HIR1231432.1"
                     /translation="MYKELAKELISGSYDLHTHTIPSAFPRALDDLELVREAEDVHMA
                     GVMIKAHYGCTAARAALINRVSGCHARAFGGLALNWPTGGLNPYSVENALRMGASVIW
                     MPTRDSRHCLSYGDMAGDFFSRPGITILDENGRLKPVVYEIMEIIKKYDSWLATGHLS
                     PEESVLLCREGRNAHVNMILTHPEWDRTKIPGSIQAELADLGVLIEKNWLNLAEGSVS
                     PEEMAQNIRLAGVHSVYLATDRGQYGAEHPAQAMLLFIETLLSLGFTPKEIRQMTKAT
                     PERIVKQ"
     gene            complement(2162..3637)
                     /gene="nhaC"
                     /locus_tag="ACZPCR_11035"
     CDS             complement(2162..3637)
                     /gene="nhaC"
                     /locus_tag="ACZPCR_11035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008395040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HIR1231433.1"
                     /translation="MSKKNEPNPKPKADVNDAGASGAEFRPSFGAAVICVVSLIVFMA
                     VSIFFFDQKMHVAMMASLGVTLLVLKIEKCPWSKIEKAIIRGGELMIPTAMILYSIGA
                     LMGAWIASGTVPMIIYWGLKIISPSMFLATACLACMLTSLATGSSWSAIGTAGVALMG
                     VGMGLGVNPAMTAGAIVSGAAFGDKMSPLSDTTNLAPAVAEGDVFDHIKAMFFTTTPS
                     IIIALAVFLVLGFKFSGTAESDTIQSILTALESNFNLNLLTLIPPVLVITLAILKKPA
                     FPILLISGGTAALIAMVVQGYSLGELFSIMEGGFVSETGNPDIDSLLSRGGLLNMNYT
                     CSLGIIAMVYGGILEHLGFLEVCLERMKFVSKSVGTLVCSTVVSCVLFNIITASQYMS
                     IILGGRLFIGEFKKKDMLPQTLSRCLEDGGTVTSLIVPWNVDGAFAGATLGVPVLSFL
                     PFAVFNWIVPIVSITFGFLGKFQWKTGEIKSTRTYRDSVES"
     gene            complement(3671..5290)
                     /locus_tag="ACZPCR_11040"
     CDS             complement(3671..5290)
                     /locus_tag="ACZPCR_11040"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HIR1231434.1"
                     /translation="MKLYQNGVILTMDAEGSRAGAMAVEGDRIVQVGEEEELRRAFPE
                     AEIADLGGKTVMPGFIESHVHLLNYAYSLTKIDCAPMKSLKELAEASREYIREKQIPP
                     GTWVLGRGWNQTFFEEKRNPTIADLDAVSTEHPIVFTRVCEHMVVANSMALSLAGITK
                     DSENPEGGEIERDENGNLTGLLKETARYLVYSIIPEKSVEEIKEMLVNAISIASSLGL
                     TTMHSDDFETFSDKDWRKVMRAYRELEQEGRLNVRIREQCLLPQIDRLKEFIREEIAK
                     RHDTPMVQAGPLKLLTDGSLGGRSAYLRAPYADAPDTRGIAVFTQEELDELVVTAHQA
                     KMGVVCHAIGDGAMEMCMDAFLKAQKERPDRDARFGILHLQITQPDLIRRFKDQNIIA
                     YMEPVCLNSDLHITESRVGAERLPSTYNYRTLCDMGVAYTMSSDCPVDSLNPFDSLFV
                     GVNRCDYHGYPEGGWMPEEKLTVDQMLRGFTINGAFASFEENVKGSLEPGKLADFVIL
                     SQDPTQCDPKKLRDIFVEETILGGRTVYRKS"
     gene            5568..7097
                     /locus_tag="ACZPCR_11045"
     CDS             5568..7097
                     /locus_tag="ACZPCR_11045"
                     /inference="COORDINATES: protein motif:HMM:NF012385.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 interaction domain-containing protein"
                     /protein_id="HIR1231435.1"
                     /translation="MITNALVQARQLYEDTDGVLVCDKYGYVEYLKWFHEGFLSDEAI
                     GMHVTEVYPELDNQTSSIMRVIESGVPRFDERQVIHNCKGELLDIVSSTIPLLAGSEV
                     VGAMTSTIFYDKYRAGKGLPKRRQGELYTLDDIISQDPIMIALKERCALIANNDSPVL
                     LYGETGTGKELFAQSLHTCSHRAKKPFISQNCAAIPESLLEGIFFGVEKGSFTGAENR
                     KGLFELADGGTLFLDEINSMDISMQAKLLKAIEEQQVRRIGSAKSTHFHTRIICAMNK
                     SPAEVLRAGLMRTDLFYRICVVRIDIPPLRDRKPDVMILTDYFINHFNRTMGKSIRGV
                     SALVKMTFQNYNWKGNVRELKNTLEYAFNLCQGNIINMGDLPDILQEDLEPQIFPQEN
                     SGCFPGPSLPAAPAPDGRVRKGKNDMEEARAGEGNAGRLAARTKKLSENREERTGERE
                     CLSGYFYDEHLSLTENTAAYEKEAIRRALERTDSITEAARLLQISRQTLSYKIEKYRL
                     N"
     gene            7235..8875
                     /locus_tag="ACZPCR_11050"
     CDS             7235..8875
                     /locus_tag="ACZPCR_11050"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF019581.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HIR1231436.1"
                     /translation="MPQTTLILKNACIYTMDGRVEEAVAISGDKIAKIGSNQEMEAWQ
                     GEHTQVIDLGGRTVVPGFNDTHTHLVGYGNSLRYVNLENCRSREEMCRRIKHFIEEKQ
                     IPAGEWVFGRGWNQNLFSDGAFPTKEDLDNVSSQHLILIIRTCGHVGIANTMALADAK
                     VTRETYLPGGQFDKGADGEPNGVIREAALEWFKKQRNPESARKELKEAIVRGGEEMLR
                     WGVTTVHTEDTYDLGYPGNFMDIYHAYQELAAEKKLPVRIYQKISLPTGKEIDEFLEG
                     CSLRTGMGHDFYHIGPMKQWADGTMGARTAGMKDPYSDAPGNTGIYYYTDQELYDNIR
                     KAHCDGMQVCIHTIGDGALEQVLNAYERVLHDFPRENHRHRLVHGQVGNLALYKKIAE
                     LGLNINIQPASTSTDIPIMEARLGSRAKYCHAWRTLTDLGVNLNASSDIPVETPNVFC
                     GIYAIVTRKCLEHPELAPWNPHEKVTVMEALRFYTINGAYAAFEENIKGSITEGKLAD
                     LVILDRDPCAVDPEELKEVQVDATILGGRLVYQREELR"
BASE COUNT         2512 a         2461 c         2342 g         2287 t
ORIGIN      
        1 ttaacaatct atatcttctt tttttgtgca tttttcctct tttaaggtta tttacattcg
       61 cttattacgg tgttatactc gctatatagt attataaaag aatatttatt cctttttgtg
      121 atgttttttc atttcattga ctatttttta gagaaatgat aaggtaatat cagcagtttt
      181 cttactgata acacatacaa agaggtctaa tatggaaaat aatattattg ataaaatcat
      241 ccagattaaa gatgttctgc ccaaaaaaca gaggactctc tgcaattatc tggtcatcaa
      301 ctatgtagag gccggaatga tgactgtggc ggagctggct cagaagtcag gcgtaggcac
      361 cactactgtg atgcggctta taaaaactct gggatatgaa aattattccg attttaaaca
      421 cgagcttctc aatctttctc tgatgagaac atccacctcc taccgcgggg tgaaacaaag
      481 ctttaaatct gccgctcaaa gctctgaatc caacctcctg aaccacctct ggatggaaac
      541 aaaccatacg attgaaaata tcattacgcc caaaaatgcc cagcagattg aaaaggctgt
      601 agatctgatg ctgtctgcat ctgccgtcta tttcctggga ctgcgctctt cccgggcggc
      661 agcatactat ctggaggata ccataagccg tttctatcca aagacaagac agttgagcca
      721 tgaacccgat tttctgtatg accgcatttt gagaatgcct gctgactctg ctctggtggt
      781 attttccatt tggccctgta ccaaaaccac gattgaggcg gctgatttgg cccaccagaa
      841 tggggttccc gtcattttaa ttactaatac tcttctgaat cccatcgcca gatatgcaga
      901 agttgtaatt gatacaaatt ctgttaacag cggatgcgga aatatggcga ttatgttcgc
      961 cgcagaagcc gttattgcag aaatgggacg aaaaacagag ccgtcttcta cagaagccct
     1021 ggaaactctg gagcgccagc tggatcccct ggacattttt ataagagaac ggactatttg
     1081 atctgtacct ttccctttca aaggatattt gaaatcgtat tcagtatctt ttggaaggga
     1141 gtttttataa tgtacaaaga actggcaaaa gaattgattt caggttccta cgatctgcac
     1201 acccatacga tcccgtctgc cttcccccgc gctttagatg atttagagct ggttcgggaa
     1261 gcggaagacg tccatatggc cggagtgatg attaaagccc actatggctg cacggctgca
     1321 cgcgccgctc tcatcaaccg agtcagcggc tgtcacgccc gcgcttttgg agggctggcg
     1381 ctcaactggc ctaccggagg attaaacccc tattctgttg aaaatgctct gcgcatggga
     1441 gcttccgtta tctggatgcc caccagagac tcccggcatt gtctgtctta tggggacatg
     1501 gccggagatt tcttctcccg tcctggcatc acaattctgg atgaaaacgg acgtttaaaa
     1561 cctgttgtct atgaaattat ggaaattata aaaaaatacg attcctggct ggccactgga
     1621 catttaagcc ctgaagaatc tgttctgctc tgccgggaag gaagaaacgc tcatgtaaat
     1681 atgattttaa cgcatcctga atgggatagg acaaaaatcc ccggatccat ccaggcggaa
     1741 ctggctgatt tgggggtttt aattgaaaaa aactggctga atctggcgga gggctccgtt
     1801 tctccagaag aaatggctca aaatatccgt ttagcaggcg ttcattctgt ctacctggct
     1861 accgaccgcg ggcagtacgg cgctgaacat cccgctcagg ctatgctcct gttcattgaa
     1921 acacttttaa gcctcggatt tacgccaaaa gaaatccgtc agatgacaaa agcaacgcca
     1981 gagagaatcg taaaacaata gttctcccaa aatagaagag ggaacatttc tgccatgtat
     2041 cttaccagag agggagaagt tttccagcga ctttcgctgg agcgcagaaa acttgctccc
     2101 tctctggcat ctatacatcg aagcgcagaa acattccctc ttctattcta atatacctct
     2161 cctatgactc aaccgaatct ctgtaggttc tggtcgattt aatctctcct gtcttccact
     2221 ggaatttgcc caggaagcca aaggttatgg acacaatcgg aacaatccag ttaaatacgg
     2281 caaacggcag gaaggagagc accggcacgc ccagcgtagc tcctgcgaag gcgccgtcca
     2341 cgttccacgg cacaatcagg gaggttacgg ttccgccgtc ctccagacac cgggacaacg
     2401 tctgcggaag catatccttc ttcttgaact ctccgataaa gaggcgtccg cccaggataa
     2461 tggacatgta ctggctggct gtgatgatat taaagagcac acagctgaca accgtggagc
     2521 agaccagcgt tcccactgac ttgctgacga acttcattct ctccagacat acctccagga
     2581 agcccagatg ctctaaaata ccgccgtata ccatagcgat aatacccaga gaacaggtgt
     2641 agttcatatt taacagtccg cctcgtgaga gaaggctgtc aatgtcagga tttcccgtct
     2701 cagatacgaa tccgccctcc atgatgctga acagctcgcc taaggaatat ccctggacaa
     2761 ccattgcaat cagagccgcc gtaccgccgg agatcagaag aatcgggaag gccggtttct
     2821 ttaagatggc cagagtgata actaaaaccg gaggaattaa cgtcagcaga ttcagattga
     2881 aattcgactc aagggcagtt aaaatgctct gaatggtatc actctccgca gtgccggaaa
     2941 acttgaagcc cagcaccagg aaaacggcta acgcgatgat aatactgggt gtcgttgtga
     3001 aaaacatggc cttaatgtgg tcaaatacgt cgccctcggc aacggccgga gccagattcg
     3061 tggtatcgga aagaggggac attttatcgc cgaaagcagc tccggaaacg atagctccgg
     3121 ctgtcatggc cggatttacg cccagtccca ttcccacgcc catcagagcc acgccggctg
     3181 ttccgatggc ggaccaggag gaaccggttg ccagtgaggt cagcatacag gccagacagg
     3241 cggtagccaa gaacatggat ggggaaataa ttttcagtcc ccagtagata atcataggca
     3301 ccgttccgct ggcaatccac gctcccatca gagctccgat gctgtagaga atcatggccg
     3361 tcggaatcat cagctcgccg ccgcgtataa tggccttctc aattttgctc cacggacatt
     3421 tctcaatttt cagcacaagc agcgttactc ccagagacgc catcatggcg acgtgcatct
     3481 tctggtcaaa gaagaaaatg gacactgcca tgaagacgat cagagacacg acgcagatca
     3541 cggctgcgcc gaaggacggt ctgaattccg ctccggaagc gcctgcatcg ttcacgtccg
     3601 ccttaggttt tgggttaggc tcgtttttct tactcataaa catcctcctt aataaatagc
     3661 ttttatcttt ttatgatttc cggtagactg tccgtcctcc cagaatcgtt tcctctacaa
     3721 aaatatcccg aagctttttc ggatcacact gggtaggatc ctgggacaag atcacgaaat
     3781 ccgccagctt tcccggctcc agggatccct tcacgttctc ctcaaaggaa gcgaaggctc
     3841 cgtttatggt aaagccccgc agcatctgat ctacggtcag cttttcctca ggcatccagc
     3901 ccccttccgg atatccgtgg taatcgcagc ggttgactcc cacgaacagg ctgtcaaagg
     3961 ggttcaggga atctaccggg cagtcggagc tcatggtata cgccactccc atatcgcaca
     4021 gcgttctgta attataagta gacggcagac gttctgctcc cacccggctc tctgtaatgt
     4081 gcagatcgct gtttaagcac actggctcca tgtaggcgat aatattctga tccttaaacc
     4141 gcctgatgag atccggctgg gtaatctgca gatgaagaat gccgaagcgg gcgtcgcggt
     4201 ccggcctttc cttctgggcc tttaagaaag cgtccatgca catctccatg gcgccgtctc
     4261 caatggcgtg gcacacaact cccatcttcg cctggtgggc cgtcacaacc agctcgtcaa
     4321 gctcttcctg ggtaaatacg gcgattcctc tggtatccgg cgcgtccgca tagggcgctc
     4381 tgaggtaggc gctccggccg cctaaagatc cgtctgtcag aagctttaac gggcccgcct
     4441 gcaccatagg cgtatcatgg cgctttgcaa tttcctccct gataaactcc ttcagcctgt
     4501 caatctgagg cagaagacac tgctcgcgga ttctgacgtt cagccgcccc tcctgctcca
     4561 gctcccggta agccctcatc acctttctcc agtccttatc agaaaaggtc tcgaaatcgt
     4621 cggagtgcat ggtggtaagc cccagggaag aggcgatgga aatggcgttt accagcattt
     4681 ccttaatctc ttccaccgac ttttccggta taatgctgta gaccaggtag cgggctgtct
     4741 ccttcaaaag tccggtcagg tttccattct cgtcccgctc aatttcgccg ccttccggat
     4801 tttcgctgtc cttcgtaatt cccgccaggg ataaagccat ggagttggcc accaccatgt
     4861 gctcgcagac tctcgtaaac acaatcggat gttccgtgct gacagcgtcc agatccgcaa
     4921 tcgtgggatt tctcttctcc tcgaaaaagg tctggttcca gcctcttcca agcacccagg
     4981 ttcccggcgg aatctgtttt tcccgtatgt actcccggct ggcctctgcc agctctttta
     5041 acgatttcat cggcgcgcag tcgatctttg taaggctgta ggcatagttg agcaggtgga
     5101 catggctttc aataaagccg ggcatcacgg tttttccgcc cagatcggcg atctcagcct
     5161 ctggaaacgc ccgtctcagc tcctcctctt cgcccacctg aacgatgcgg tccccctcca
     5221 ctgccatcgc tcccgcccgg ctgccctctg catccatggt gagaatgacg ccattttgat
     5281 agagtttcat gtattatcct ccattctgca aaatatagtt ttataacccg atgtctatga
     5341 ataaagcaac ttttatgcca cacctgagaa ggcctgtatt actgccaaat caggaaacga
     5401 tttccatttt tttctaacaa tatattagat tttctattat tattcttcgg aatacagaaa
     5461 attttcgctt aaatttttgc acaatcctgt agaaagcaaa aacatttgcg gcatcatggc
     5521 ttttatgcta cactgaaccc aaagaaatgt caggagaggg gaaaactatg attacaaatg
     5581 ctctagtcca ggccagacag ctgtacgagg acacagacgg ggtgctggtc tgcgacaaat
     5641 acggctatgt agaatatctg aaatggtttc acgagggttt tttatcggac gaagccatcg
     5701 gcatgcacgt gacggaggtg tacccggagc tggacaacca gaccagctct attatgcggg
     5761 tgattgaaag cggggttccc cgctttgacg aacggcaggt gatccacaac tgcaaggggg
     5821 agctgttgga catcgtatcg tccaccattc cgctcttagc cggaagcgag gtcgtggggg
     5881 ctatgacctc caccattttt tatgacaaat acagggccgg gaaggggctt cccaagcggc
     5941 gtcagggaga gctgtatact ctggacgaca ttatttccca ggaccccatt atgatcgccc
     6001 tgaaggagcg gtgcgccctg atcgccaaca atgattctcc cgtgcttctc tacggggaga
     6061 cgggaacggg aaaggagctg ttcgcccagt ctctgcacac ctgctcccac cgggccaaaa
     6121 agccttttat ctcccagaac tgcgcggcga tcccggaatc gcttctggaa ggtatcttct
     6181 tcggcgtgga aaaaggcagc ttcacaggag cggaaaacag aaaagggctg tttgaactgg
     6241 cagacggcgg aactctgttt ctcgatgaga tcaattccat ggatatttcc atgcaggcca
     6301 agcttctgaa ggccatagag gaacagcagg tccggagaat cggaagcgcg aaaagcaccc
     6361 atttccacac cagaattatc tgcgctatga acaaaagccc cgccgaggtg ctgcgggccg
     6421 ggctgatgcg cacggatctg ttctaccgaa tctgcgtggt gagaatcgac attccgcctc
     6481 tgcgggacag aaagccggac gtgatgatac tcaccgacta ttttatcaat catttcaacc
     6541 ggactatggg aaaatccatc cggggcgtca gcgcgctggt gaagatgacc tttcaaaact
     6601 ataactggaa gggaaacgta cgggagctga aaaataccct ggagtacgcc ttcaatctct
     6661 gccagggcaa tatcatcaac atgggcgatc tgcccgatat tctgcaggaa gatctggaac
     6721 ctcagatctt tcctcaggaa aattccggct gtttcccagg gccgtccctg ccggcagctc
     6781 cagcgccaga cggaagggtc aggaaaggga aaaacgacat ggaagaagcc agggccggag
     6841 aggggaacgc cggacgtctg gccgcacgta caaaaaagct ctccgaaaac agggaagaga
     6901 ggactggaga gagggaatgc ctttccggtt atttctatga tgaacatttg tccctcaccg
     6961 aaaacacggc cgcctacgaa aaagaagcca tccgccgggc cctcgaaaga actgacagca
     7021 tcacggaagc cgcccggctg ctccagattt cccggcagac gctttcctat aaaatcgaaa
     7081 aataccgcct gaattaatgc aaaatttttt gcgtttttta tggcataaaa tttgctctat
     7141 tacactggta tctattatta cctgtatctg ttaaacaccg gcatacggaa agacgcggac
     7201 ctgtacgccg gcacttcagg aaggaggaat ttttatgccg cagacaacct tgattcttaa
     7261 aaacgcctgc atttacacca tggacggccg tgtagaggaa gccgtcgcca tctccggcga
     7321 taaaatcgca aagatcggct ccaatcagga gatggaagca tggcagggag agcataccca
     7381 ggttatcgat ctggggggac gcaccgtcgt tccaggcttt aacgacaccc atacccatct
     7441 ggtgggttat ggcaattccc tgagatatgt aaatctggaa aactgccgtt cccgcgagga
     7501 aatgtgcagg cggatcaaac actttattga agaaaaacag atcccggcgg gagaatgggt
     7561 attcggccgg ggatggaacc agaacctgtt ttcagacggc gcgtttccaa ccaaagagga
     7621 tttggacaac gtatccagcc agcatctgat cctgattatc cgcacctgcg gccatgtggg
     7681 aatcgccaat accatggctc tggctgacgc aaaggtgaca agggaaacgt atcttcccgg
     7741 cggacagttt gacaaaggag cggacggaga gccaaatggc gtgatccggg aggcagctct
     7801 ggaatggttc aaaaaacaga gaaatccgga atctgccaga aaggagctga aggaagccat
     7861 tgtccgtggc ggagaggaaa tgctccgctg gggagtgaca acggtgcata cggaagatac
     7921 ctatgattta ggctatcccg gcaatttcat ggacatttat cacgcttacc aggagctggc
     7981 cgccgagaaa aagcttcccg ttcgcattta ccagaaaatc tcacttccta caggaaagga
     8041 gatcgatgaa ttcctggaag gatgttctct gcgcactgga atggggcatg atttctatca
     8101 catcggcccc atgaagcagt gggcggacgg aaccatgggc gcccgcaccg ccggaatgaa
     8161 ggatccgtat tctgacgcgc ccggcaatac cggaatctat tattatacgg atcaggagct
     8221 gtatgacaac atcagaaaag ctcactgcga cggtatgcag gtctgcattc acaccatcgg
     8281 cgacggagcc ttagagcagg tattaaacgc ctatgagcgc gttctgcatg atttccccag
     8341 ggaaaaccac cgtcaccgcc tggtccacgg acaggtagga aatctggcgc tctataagaa
     8401 aattgcagaa ttaggactga atatcaatat ccagcccgct tccacttcaa ccgatattcc
     8461 cattatggaa gcacgcctgg gcagccgggc gaaatactgc catgcatggc gcacgctgac
     8521 cgatctgggg gtaaatttaa acgccagctc cgatatcccg gtagaaacgc ctaacgtatt
     8581 ctgtggaatt tacgccattg tcaccagaaa atgcctggaa cacccggaac tggccccctg
     8641 gaacccccac gagaaggtaa cggtcatgga ggcgcttcgt ttctacacga tcaacggcgc
     8701 ttacgccgct tttgaagaaa atatcaaagg ttccattaca gagggaaaac tagccgatct
     8761 ggttatttta gaccgcgatc cctgcgccgt cgatccggag gagctgaagg aggtgcaggt
     8821 agacgccacg attctgggcg gcaggcttgt gtatcagagg gaagaactgc gctaggaaac
     8881 acgtttaaaa gcaccgaaaa cagatgcgcc aggaaaaatt ttcttgttcc actttaaagg
     8941 caccgaaaat ttttcctggc gtataggggg gagctggtat gaaagaaatt taatgctgtc
     9001 tgcaccagat atgtaagact cagcagtaac tattaaccgc aatgtgacac tgcttaggcc
     9061 caaaatgcag gctgggcgat aatggcgggg ctttcgcagg gagacccgta ctgatttctg
     9121 ccaccgggcg aaatgtttga gccgtaaggc gagttttcgc gaatggcaga tcatggatgc
     9181 acgaatcgag cagaaaacgt agctagctgc aaggcctgcc gttttggcct actgtgcaaa
     9241 taatttaaga aaaccgtatt cattcctgcg tttggtgtag aaatcaggcc ggttttcgtt
     9301 gtagtttcct ctttggcatg gtataataaa atgacaaaag catacatttc accacttcga
     9361 acctggttcc aggttcctat ttctctgatt cctatctttc agaatatcag aaaatctatg
     9421 ctttttccca aatttatatc agagcaggag attttcattc tggaagctcc tgcaaaagga
     9481 ggtcaaatga atcagaaaca gcacagcaga agtgaaaatt cggcaggctg gcagcaggta
     9541 cagtctcagc cctttgaagc atctcagcag gcagagcttc aaagaccagt taaccgcagc
     9601 ta
//
LOCUS       DBMDUW010000076         9472 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_3422_length_9472_cov_3.012272, whole genome shotgun sequence.
ACCESSION   DBMDUW010000076 DBMDUW010000000
VERSION     DBMDUW010000076.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 9472)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 9472)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9472
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3422_length_9472_cov_3.012272"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            131..1237
                     /locus_tag="ACZPCR_11055"
     CDS             131..1237
                     /locus_tag="ACZPCR_11055"
                     /inference="COORDINATES: protein motif:HMM:NF019149.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HIR1231437.1"
                     /translation="MNPEQAKVRRLMCEGIMARKGSTLIAKELNDAGYRNTVGKPWKP
                     MDIPKFVYDCKNVGTMIINKERHDFESKQTIKLPKEEWVYVENAFPPIVTQEEWDLIC
                     KIHEERVIATGSDRRGKKTSGYSFSGKLVCGICGAPYWRKQRVSKDEYWVCSTKQTKG
                     RRTRKRDSTMGKAGEINPLGCDNENISYNSLMEIMGVVSERLQANTDTIKHDMINWLT
                     KLRKQLLEANGGHTEADLQRELSRKSKLLDAYLDGILNKQEYQKKAEELDERIIQLKA
                     ETEKNKANSGDIAEIDKVLANIDEEVSRYVDGNEKLKVEYLLEHLEQVQIFPDKVIVI
                     VPILSEGIVVEKTQYVSREKRFRKEHADEHLERK"
     gene            1176..2621
                     /locus_tag="ACZPCR_11060"
     CDS             1176..2621
                     /locus_tag="ACZPCR_11060"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HIR1231438.1"
                     /translation="MYLGRNGSGKSTLMNILNGNEKIRRTGGYEGEILIDGKEIRIEN
                     RAQSEAQGIAMVHQELALFAGMTVGENIKINRENVKGRGLFVPELAYVDQKKNREDAA
                     RTLERIGTDLDPDSPIDSLALNQKQFVEIARELDNQNVRLLMLDEPTSSLNITETKGL
                     LACIREIAREGIAVLFISHRLDEIMEVCDRVSVLRDGELISTYKKEEFDAARFADDMV
                     GREIVKAARHETQSGGQVLFSYEGLPDNQTLDILEGEILGITGLAGQGQENLLDGLFG
                     MKKAEYQAVYRGKKLKPGDTENLIHHRIYYLSEDRGTASLLLDSPIWENMVFGTEKVH
                     PEFLRLRKCPALSFLNHKAVDSHARELIDRLNIVCRGPEQKVRELSGGNQQKVCVSRA
                     ITFQPELLLIGEPTRGIDVYSKELILQWLLKINKEYHTTLVVASGELEELLRICDRIA
                     VMHQGKVFKIFDNNSTSLEELTLALYGRELR"
     gene            2618..3661
                     /locus_tag="ACZPCR_11065"
     CDS             2618..3661
                     /locus_tag="ACZPCR_11065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HIR1231439.1"
                     /translation="MKTKYLNPPQVIMLAFMGILLLAAMGIDMDMAGIISDALVKWAM
                     NGVIVLSLIPMINVGAGRNFGMTIGLSAGLVGMIFALNARLTSWTGFFCSILAGMAVA
                     LVFGLIYAAVLNRLKLNEEIVGTFAGYSFIPIMNLFYTFVPVTNRQMLYPIGGQGLRP
                     KVNLENYFGQILDRLWQIEIGGVVIPLGLLLFFFGIGLLLWLFSKTRTGLIFTAIAEN
                     EKFARLTGIRVNRYRTIAIVMSTVIAAVGVVVYSQSYGILHLYDGPFMMSFPAVSAIV
                     IGGASPKKATVTNALIGTFLYQTTYLLSIPVANALLIPEMAEILRTIITSGIILYAFI
                     FERKDARHEVYKA"
     gene            3642..4685
                     /locus_tag="ACZPCR_11070"
     CDS             3642..4685
                     /locus_tag="ACZPCR_11070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HIR1231440.1"
                     /translation="MKYIKRNIVPIAVLALAVLSFQFAGISLSYLASEVYTRFIRNIL
                     FTLALILPVICGMGLNFAIVVGAISAQTAMVISVNLMLEGGPALLFVVGLSFILSVVF
                     GWMVAALLNRAKGKEMIVSIMVGQLSSVIYQFVFMVAYGMFFEPRNQEIILDRGIGVR
                     SMIDAKNISAVFKSVLPFEFDGKTYSLLPLIFIAAFSLLLFYIQRTRLGTLARAVGTD
                     LHTAEKLGIKSDRVRTICIIISTLFAAMSQILFVADFGTINVYTGHLGLDTFAAAAIL
                     VGGATIKKAKMRHCFLGVLLFHALFVTSPMAGQNLFNNPAVGEYFRSFVAYGVIVIAI
                     MLNLRTEKEKAEN"
     gene            4770..5990
                     /locus_tag="ACZPCR_11075"
     CDS             4770..5990
                     /locus_tag="ACZPCR_11075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002595515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HIR1231441.1"
                     /translation="MRKKLVSAFLAAALTVSALTGCSSQTGADAKGESTAAEQKTETE
                     ESKAGETAAEEGKEAASDEAYKIGIVTPTVTVSEDEFRGAQEMVEKYPDLVVHKTIPE
                     NFSTDKEGCISVITSLADDPEMKYVIFDCGMEGIIPAFQTIREKRPDIVTMVTSNDDP
                     KLLNEYVDISITTDWNRRGETIATKAHEMGAKTFIHYSFPTHMASESKVIRRDKMKET
                     CEKLGMEFVEITTPDPQTGNGRAPMLQFLREDLPRQIEKYGPDTNIFGTNCPMYDVIL
                     DEAFKLKFIVAEQCCPTPTQSYPTILNLEITEDDLGNYDKINEMITEKSKEAGMTGRL
                     SGWAMPSSVYIPKFKVELAKYMHDNNLKPEDVLSKEFLDDFSKEHMPVAADFAIAGEG
                     LDHYYMLILEDIYY"
     gene            6154..7578
                     /locus_tag="ACZPCR_11080"
     CDS             6154..7578
                     /locus_tag="ACZPCR_11080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006566590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1231442.1"
                     /translation="MTQTISQTEQGNPLGYEKLPVLLKSYAIPSIIAMLVSSLYNIVD
                     QIFIGQGVGYLGNAATNVSYPLTTICLAIALLIGIGSASCFSLELGAGREEQAARTVG
                     NAVSMMVFMGILYVVAVEWFLTPLLTVFGATQEIMPYAESYTRITAAGMPLLILTNGL
                     SNLARADGSPKYSMICMVVGAVINTILDPIFIFVLHQGVAGAAIATVVGQLVSCLMAL
                     YYLKKFRHVKLERRHFIPGFRVYGRIASLGMNGSLNQLALTFVQIVLNNSLTYYGARS
                     VYGSEIPLASCGIVMKTNAILLAVIIGIAQGAQPIIGFNYGAKQYERVRGVYRLAITW
                     NLVVSGIGFLLFQLFPRHIISIFGTGEPLYFEFAIRFLRIFLFMVLINGVQLLSSNFF
                     AAIGKPVKGVILSLTRQVFFLVPLLLILPLFFGIDGIMFAGPVADFAAFLVTMLLIRR
                     EMRHMKELQAGLETEQVQAAEIGR"
     gene            complement(7717..9120)
                     /gene="mgtE"
                     /locus_tag="ACZPCR_11085"
     CDS             complement(7717..9120)
                     /gene="mgtE"
                     /locus_tag="ACZPCR_11085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015560797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HIR1231443.1"
                     /translation="MRRHEFINEEIVQEIIQFIRSEKNREALLSHLDDYHDYDIAQAL
                     EELTPEERRELYEKMGAEWTAEIFSYYDEPETLMTELAPREAASVIEYMDSDDAAELL
                     DQLPDSFQDKIEENLSEETSGDIKLISSYEDDEIGSLISNNYISICHTLTVKEAMKEL
                     IRQSADNDNITTLYAVDEHERFYGAIDLKDLILAREYTPLESIIVNSYPFVHDHDDLE
                     ECMDWIRDYEEDSLPVLDQDDRLIGIITVQDIVDYMEEESKEVYNKLAGIAEGDGSED
                     MKETLAVSMKKRLPWLIALLFLGMFVSSVVGMFEGVVSKVAILVCFQSLILDMAGNVG
                     TQSLAVTIRVLMDEDITFKTRLALIWKEVKIGMANGGLLGIVSFLCIGVYVWLFKGNS
                     ILYGFAVSACVGISLLLAMAISSLAGTVIPLFFHKIKVDPAVASGPLITTVNDLVAVV
                     TYYGMAWLMLFHLFHLA"
BASE COUNT         2572 a         2018 c         2472 g         2410 t
ORIGIN      
        1 accgatgctc tgtccgtaaa ggagagacat ttcggggttc caggttgccg ccagacaggt
       61 cagggcaggg aaagccacgc agggtagtgg taatgtatat ggatgggata aaaaagatgg
      121 taagtattat ataaatccag aacaggctaa ggtaaggagg ctcatgtgtg agggaattat
      181 ggcaagaaaa ggctctaccc tcatagctaa ggagcttaat gatgctggat accgtaacac
      241 ggtagggaaa ccgtggaaac ctatggatat acctaaattt gtatatgatt gtaaaaatgt
      301 aggtaccatg attataaaca aagaaagaca cgattttgag agtaagcaaa ctataaaact
      361 ccctaaggag gagtgggtat atgtagaaaa cgctttccct ccgatagtca cacaggagga
      421 gtgggatcta atctgtaaga tccatgagga gagagtaata gccacaggat ccgacaggag
      481 aggcaagaaa accagcggat actcttttag tggtaagctg gtatgtggta tctgtggggc
      541 tccttactgg aggaaacaga gagtatctaa ggatgagtac tgggtatgca gtacaaagca
      601 gactaaaggt aggagaacca gaaaaagaga tagcacgatg gggaaagctg gagagataaa
      661 tcctttaggc tgtgataatg aaaatatctc ttataactcc ctcatggaga taatgggggt
      721 agtatcagag cgattacagg caaatacaga cacaataaag catgatatga taaattggct
      781 tactaagctc agaaaacagc tcctagaggc aaatggagga catacagagg cagatctaca
      841 gcgtgagctc tccagaaaaa gtaagctact ggatgcctac ttagatggga tcctaaataa
      901 acaggaatac cagaaaaaag cagaggagct agatgagagg atcatccagc tcaaagcaga
      961 aacagaaaag aataaggcta actctggaga tattgcagag atagataagg tacttgctaa
     1021 catagatgag gaggtatcca gatatgtaga cggtaatgag aaattaaaag tagaatacct
     1081 cttagagcac ttagagcagg tacagatatt cccagataag gttatagtta tagtaccgat
     1141 attgagcgag gggatagtag tagagaaaac tcagtatgta tctagggaga aacggttccg
     1201 gaaagagcac gctgatgaac atcttgaacg gaaatgaaaa aatacggaga accggcggat
     1261 acgagggtga gattctgatt gacggaaagg aaatcaggat agaaaacaga gctcagtcag
     1321 aggcacaggg aattgccatg gtgcatcagg aactggcgct gtttgcagga atgacggtcg
     1381 gagaaaatat aaaaattaac cgggaaaatg taaagggcag aggccttttt gtgccggagc
     1441 tggcttatgt agatcagaag aagaaccggg aggacgcggc ccggacgctg gagcggattg
     1501 gaacggatct ggatccggac agccccattg acagtctagc tttaaatcag aagcagtttg
     1561 tggagattgc cagggagctg gacaatcaga acgtgcgtct cctgatgttg gacgagccta
     1621 ccagctcctt aaatattacg gaaacgaaag gccttttggc ctgtatccgg gagattgcca
     1681 gggaaggaat cgcagtctta ttcatttccc accggctgga cgagattatg gaggtgtgcg
     1741 acagggtttc tgtactgagg gacggagaac tgatttctac ctataaaaaa gaagagtttg
     1801 acgcggccag atttgccgac gatatggtgg gccgcgagat tgtgaaggct gcgcgccatg
     1861 aaacccagtc aggcggtcag gtgctgttct cctatgaagg gcttccggac aatcagacgc
     1921 tggatatatt ggaaggcgag attctgggga tcaccggact ggccgggcag gggcaggaga
     1981 acctgttaga cggtctgttc ggcatgaaaa aagcagagta tcaggctgtc tacagaggaa
     2041 aaaagctgaa gcctggcgat acggaaaacc tgatccatca caggatttac tacctctccg
     2101 aagacagggg aacggccagc cttctcctgg acagtcccat atgggaaaat atggtgtttg
     2161 gaacagaaaa ggtccacccg gaatttctgc gtctccggaa atgtccggcg ctttcttttc
     2221 tgaatcataa ggcggttgat tcccacgcca gggaactgat cgatcgtttg aatattgtat
     2281 gcagaggtcc ggagcagaag gtgagagagc tttcaggagg aaatcagcag aaggtctgcg
     2341 tcagccgggc gattaccttc cagccggagc tgcttttaat cggagaaccc accaggggaa
     2401 tcgacgtcta ctccaaggaa ctgattcttc agtggctttt aaaaatcaac aaggagtacc
     2461 acacgacgct ggtggtggct tccggagaac tggaggagct tctgcggatc tgcgacagga
     2521 ttgctgtgat gcatcaggga aaggtattta agatatttga caataacagt acgagtctgg
     2581 aggaactgac tctggctctt tatgggaggg aactcaggtg aaaacaaaat atttgaaccc
     2641 cccgcaggtg attatgctgg cgtttatggg cattctgctt ctggcagcca tgggaattga
     2701 catggatatg gcgggaatta tcagcgacgc cctggtaaaa tgggccatga acggcgtgat
     2761 tgtcctgtct ctgattccta tgatcaatgt gggagcagga agaaatttcg gtatgaccat
     2821 cggactgtcg gcaggacttg taggcatgat ttttgctctg aacgcccgcc tgacttcgtg
     2881 gacaggcttt ttctgctcca tattggcggg aatggcggtc gcgcttgtat ttggcctgat
     2941 ctatgcggcg gttttaaaca gactgaagct gaacgaggag attgtgggaa cctttgcggg
     3001 ctattccttt attcctatta tgaacctgtt ttataccttt gtgcctgtga ccaaccgcca
     3061 gatgctgtat cctatcggcg gccagggact ccggccaaag gtcaatctgg aaaattattt
     3121 cggacagatt ttagaccggc tgtggcagat agaaatcggc ggcgttgtga ttccccttgg
     3181 acttctcctg tttttctttg gaatcggtct tctgctctgg cttttttcta aaacgaggac
     3241 aggcctgatt tttacggcta ttgcagaaaa tgagaagttt gccaggctga ccggtatcag
     3301 ggtaaacaga taccgcacca tcgccatcgt catgtccaca gtgattgcgg cagtgggagt
     3361 ggtggtgtac tcccagagct acggcattct gcatctgtat gacggcccgt ttatgatgag
     3421 ttttcccgct gtttcagcga tcgtgatcgg cggcgccagc ccgaaaaagg ctacagtgac
     3481 gaacgccctg atcggtacgt ttctgtacca gactacctac ctgctgtcca tccctgtggc
     3541 caacgcgctg ctgataccgg agatggcgga gattctgcgt accattatca caagcggcat
     3601 tatcttatat gcgtttattt ttgagaggaa ggatgcgaga catgaagtat ataaagcgta
     3661 atatcgttcc catcgctgtt ctggctctgg ccgtcctgtc ctttcagttt gcaggaatca
     3721 gcctgtccta tctggcgtca gaggtgtaca cgcggtttat ccgcaacatt ttatttacgc
     3781 tggccttgat tctgccggta atctgcggca tgggactgaa ttttgccatt gtagtaggcg
     3841 ctatttctgc ccagactgct atggttatct ctgtaaattt gatgctggag ggcggacccg
     3901 cgcttctctt tgtcgtcggc ctgagcttta tcctgtctgt tgtgtttgga tggatggtag
     3961 cggctctcct aaacagggcc aagggaaaag agatgattgt gtccatcatg gtgggacagt
     4021 taagctcagt catctaccag ttcgtgttta tggtggccta cggcatgttt tttgagccga
     4081 ggaaccagga aattatcctg gatcggggaa tcggcgtgcg gagcatgatt gacgccaaaa
     4141 atatcagcgc tgtttttaaa agcgtgctgc cctttgaatt tgacggaaag acgtattcgc
     4201 tgcttccgct gatctttatc gcggcatttt cccttctgct gttttacatt cagcgtacca
     4261 gactgggaac gctggccaga gcggtgggaa cggatctgca cacagcggaa aagctgggaa
     4321 ttaagagcga ccgggtgaga actatctgca ttattatctc aacgctgttt gcggccatga
     4381 gccagattct gtttgtggcg gattttggca ccattaacgt gtatacaggt catctggggc
     4441 tggatacttt cgcggcggcg gcgattctgg taggaggagc tactattaaa aaggcgaaga
     4501 tgcgccactg ttttttagga gtcctgctgt ttcacgcgct gtttgtaact tcaccgatgg
     4561 caggccagaa tctgtttaac aaccctgctg taggagagta tttccgatcc tttgtggcct
     4621 acggcgtcat tgtaatcgcc attatgctga atctcaggac agaaaaggag aaggctgaaa
     4681 attaaaatat gcaaggggtt tctgggaagc ggtttctgaa ggagagcgct tccatgaaat
     4741 aaataaaata ttacaaaatg gaggaagcta tgagaaagaa actggtaagt gcatttctgg
     4801 cagcagctct gacagtcagc gctttgacag gctgctcatc ccagacaggc gcagatgcaa
     4861 agggagagag cactgctgca gagcagaaga cagaaactga ggagagcaag gcaggagaga
     4921 cagcggcaga agagggaaaa gaggccgctt ctgacgaggc ttacaaaatc ggtattgtaa
     4981 cacctactgt tacagtcagc gaggatgagt tccgcggcgc tcaggagatg gtagagaaat
     5041 atccggattt agtcgttcat aaaaccattc cggagaactt ttccactgac aaagagggat
     5101 gtatttccgt tatcaccagc cttgctgatg atccggagat gaaatatgtg atttttgact
     5161 gcggtatgga gggaattatc ccggcattcc agacaatccg tgagaaacgt cctgacattg
     5221 taaccatggt tacaagcaac gatgatccaa agctgttaaa tgagtatgta gatatctcca
     5281 ttacaacaga ctggaatcgc cgcggcgaga caattgctac aaaggctcat gagatgggag
     5341 ctaagacttt tatccactac tccttcccga ctcatatggc ttctgagagc aaggtaatcc
     5401 gcagagacaa gatgaaagag acctgcgaga agctgggtat ggaattcgta gagattacaa
     5461 caccagatcc tcagacagga aacggaagag ctccgatgct tcagttcctc agagaggatc
     5521 ttccgcgcca gatcgaaaag tatggcccgg atacaaatat cttcggcaca aactgcccga
     5581 tgtacgatgt cattctggac gaggcattta agttaaaatt catcgtagca gagcagtgct
     5641 gcccgacacc aacccagtct tacccgacta ttctgaatct ggagattaca gaggatgatc
     5701 tgggaaatta cgacaagatc aacgagatga tcacagagaa gtccaaagag gctggtatga
     5761 caggaagact gtctggatgg gcaatgcctt cttccgttta cattcctaaa tttaaggtag
     5821 agcttgcaaa atatatgcat gacaataact taaagccaga ggatgtactc agcaaggaat
     5881 tcttagatga tttctccaag gagcatatgc cggtagcagc agacttcgcc attgcaggtg
     5941 agggactgga tcactactac atgctgattc tggaggatat ttattactag gatgtaatca
     6001 tatgggctgc tgctccatgg aactgtaatg ctccagggga cagcagctcc ttttttattt
     6061 ctaaaaactt ctgtacactt gaaactaccc atgataaaat attcatttag atataacaga
     6121 gcgaaatgat aaacggaaag aaggaactta ctaatgacac agacaatatc acagacagag
     6181 cagggaaatc ctctcggcta tgagaagctt cctgttcttt taaagagcta tgccatcccc
     6241 agcatcattg ccatgctggt cagctctctc tataatattg tagatcagat ttttattggc
     6301 cagggcgtag gatatctggg aaatgcagct acgaatgtgt cctacccgct gacaacaatc
     6361 tgtctggcca ttgccctgct tatcggaatc ggaagtgctt cctgtttttc tctggagctg
     6421 ggagcaggaa gagaagagca ggcagcccga accgtgggaa atgccgtttc catgatggtt
     6481 tttatgggta tcctttatgt agtggcagtg gaatggtttc tgactcctct tttgacagta
     6541 tttggagcta ctcaggagat tatgccgtat gcggagagct acacccgcat tacagcagcc
     6601 ggtatgcctc tgctgattct caccaatgga ctcagcaacc tggccagggc agatggaagt
     6661 ccgaaatatt ccatgatctg catggtagtg ggagctgtta ttaatacgat cctggatccc
     6721 atttttattt ttgtgcttca ccagggagta gcaggagctg ccattgccac agtagtagga
     6781 cagctggttt cctgcctgat ggctttgtat tatttaaaga aattccgtca tgtgaagctg
     6841 gaacgacgcc attttattcc cggctttagg gtgtatggaa ggattgcttc cctgggaatg
     6901 aatggaagcc tgaatcagct ggcgcttact tttgtacaga ttgtattaaa caattcactc
     6961 acttattatg gcgccagatc agtctatgga agtgagattc ctctggccag ctgtggaatt
     7021 gtaatgaaga caaatgccat tcttctggcc gttattatcg gaattgccca gggagcccag
     7081 cctattatag gatttaacta tggagcgaag cagtatgaga gagtgagagg tgtttaccgt
     7141 ctggccatca cctggaatct ggtggtttcc ggaatcggat tcctgttgtt tcagctgttt
     7201 ccaaggcaca ttatttctat tttcggaaca ggagagcctc tttactttga gtttgccatc
     7261 cgttttctga ggattttcct gtttatggtg cttataaacg gagtccagct gctttcctct
     7321 aacttttttg cagccattgg aaagccggtg aagggagtga ttttgtcgct gacaaggcag
     7381 gtgtttttcc tggttcccct gcttttgatt ctgccgctgt ttttcggtat cgacggaatc
     7441 atgtttgcag gacctgtggc agactttgcg gcctttctcg ttacgatgct tctgatccgg
     7501 cgggaaatgc gccatatgaa agaactgcag gctggacttg agacagaaca ggttcaggcg
     7561 gctgaaatag gaagatagag ctcaaagagc tttgagcgcc tgatttgaaa gaaaaggtaa
     7621 aataaagaga agaggagaat ctgtttctgc ttttaaatca gagcaaaaca gttctgcctc
     7681 ttctttttct gtgaaaacta tgttttagag tcctgatcag gccaggtgga acaggtgaaa
     7741 cagcatcagc caggccatgc cgtagtaggt gacaactgcc accagatcat tgaccgtggt
     7801 gatcagcggg ccggatgcaa ccgccggatc taccttgatt ttatggaaaa acagaggaat
     7861 cacagttcct gccaggctgg agatggccat agccagcagc agggagattc cgacgcaggc
     7921 ggaaactgca aagccgtaca ggatggaatt tcccttaaac agccatacgt aaacgccgat
     7981 gcagaggaag gatacgattc ccagcagacc tccgtttgcc ataccgattt ttacttcctt
     8041 ccagataagc gccagtcttg tcttaaaggt gatatcctcg tccatcagaa cgcggatggt
     8101 aactgccagg gactgggttc ccacatttcc ggccatgtca agaatcaggg actggaagca
     8161 tacaagaatt gcaacttttg acacaactcc ctcgaacatt cccacgacac ttgatacgaa
     8221 catgccgaga aacagaagcg caatcagcca aggaaggcgt tttttcatgc tgacggccag
     8281 agtttccttc atatcttcac tgccgtcgcc ttctgcgata ccggccagct tgttataaac
     8341 ctcttttgat tcctcttcca tatagtctac aatatcctgg acggtaataa ttccaatcag
     8401 acggtcatcc tggtccagaa cggggaggga atcttcctcg taatcgcgga tccagtccat
     8461 acactcctcc agatcgtcat gatcatgaac aaaaggatag gaattgacaa tgatgctctc
     8521 cagcggcgtg tattccctgg ctaggatcaa atctttcaaa tcaatggctc cataaaagcg
     8581 ttcatgctca tcgactgcat agagtgtggt aatattgtca ttgtcagcag actgacggat
     8641 gagctctttc atggcttcct tgacagtcag agtatggcag atggaaatat agttgttgct
     8701 gatcaggctt ccgatttcat catcctcgta ggaagaaatc agcttaatat ctccagaagt
     8761 ttcctcgctt aaattttcct cgattttatc ctggaaggaa tcaggcagct gatctaaaag
     8821 ctctgccgca tcgtcggagt ccatgtactc aataacgctt gcagcctctc tgggggccag
     8881 ctcggtcatc agggtttccg gctcgtcata gtaggagaaa atctctgctg tccactctgc
     8941 gcccattttt tcgtagagct cacgccgctc ctccggtgtc agctcttcta aagcctgggc
     9001 aatatcgtag tcatggtaat catccagatg ggagagcagt gcttcccggt ttttttcaga
     9061 tcttataaac tgaatgatct cctgaacaat ctcttcgtta ataaattcat gtcttctcat
     9121 gtcagtgtcc tcctattcag catatcgcag aatacgcgaa aaaccggctg aaaaaggacc
     9181 cgctgtggtc agatggacct gcacaggcgg atagtcagct ttgcgtattc taatttacag
     9241 gtatcagggt gaccgtctcc gtccatgcac tcacatcctt tcttcttatc ggcagcagat
     9301 cggctggata gtctcagccg gatgctgcaa aaaaatccat atcatcagcc tgagcgaatg
     9361 atatggatct ggaaatgcgt atcactatcc gttcaagctt tagcttcaca gggcctgaaa
     9421 attacattat tctgcgcctt aatccgacac agactgctaa cctgattaga ag
//
LOCUS       DBMDUW010000077         9258 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_3487_length_9258_cov_3.577591, whole genome shotgun sequence.
ACCESSION   DBMDUW010000077 DBMDUW010000000
VERSION     DBMDUW010000077.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 9258)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 9258)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9258
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3487_length_9258_cov_3.577591"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..214
                     /locus_tag="ACZPCR_11090"
     CDS             <1..214
                     /locus_tag="ACZPCR_11090"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231444.1"
                     /translation="EIIKAQLEKLDEKIVKIEKTLKGLKAERKKLEEELKSSELTAIA
                     EFISESGVTVEQLKSMIEKENLNAAE"
     gene            341..1822
                     /locus_tag="ACZPCR_11095"
     CDS             341..1822
                     /locus_tag="ACZPCR_11095"
                     /inference="COORDINATES: protein motif:HMM:NF012772.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HIR1231445.1"
                     /translation="MDIQKKKRVYQTRFFIFTAVSAGLLWFYIRSEREYQTGPHSIWQ
                     LLPYFWFGLTIAWAVLVFYYQKLTLKSQNTDALTGGPNERAFRMAVEKRMRAGGEAFV
                     FAVIDIKKFSRIENWYDHAVGDQVLKRVYEALRSCLKENEVLCRASADQYYLLLEETD
                     PELLLKRLLALDDSVYFLEDLPIKEKLFLSMGAYQTAGEQDTFAHALDCANYCRKESP
                     DCHDRNSHLEIYGYTFQDHRDRDRRYHEQAEEALKAGHFHMYLQPKYELEHESLAGAE
                     ALFRWIDPEKGMLPLGEFMPLFEKNGFVRQIDYFIFESALKLIQKWLDSGVKPVKISV
                     NLSKSHFSNREFFENKFLPIYEKYQVPKELLEFEISENTMLDGQGMLIGFVQKLKDMG
                     FSCSMDDFGSGYSSLNTLKSIPVSTVKLDGRMFEETEKERGKIVSKGMIRIARELQIE
                     VVAEGVETREYVDFLKEQKCDLVQGYYFGKPMPAEEFEKLMQG"
     gene            2024..2236
                     /locus_tag="ACZPCR_11100"
     CDS             2024..2236
                     /locus_tag="ACZPCR_11100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008689714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046914 - transition metal ion binding
                     [Evidence IEA];
                     GO_process: GO:0006811 - monoatomic ion transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FeoA family protein"
                     /protein_id="HIR1231446.1"
                     /translation="MNLWEAKEGEEYIIKEIATDDEELNAFLFSLGCYSGEPITVIAR
                     RKGGCVVSVKDGRYNMDTDLAQAISI"
     gene            2320..4317
                     /gene="feoB"
                     /locus_tag="ACZPCR_11105"
     CDS             2320..4317
                     /gene="feoB"
                     /locus_tag="ACZPCR_11105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009246904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transporter B"
                     /protein_id="HIR1231447.1"
                     /translation="MRIALTGNPNSGKTTMYNALTGRNERVGNWAGVTVEKKESPIKK
                     AYFDGEEELIAVDLPGAYSMSPFTSEESITSAYVKNENPDVIINIVDAANLSRSLFFT
                     TQLLELGIPVVVALNKSDITEKKKTEIDVKSLSQRLGCPVVQTISTSSGRDGLKEAVN
                     QAAALKGRGQTAPYHQEDIDLQDKAAVEAADRARFEFVNGIVKAVETRRVFTKDRNKQ
                     DRIDAVLTSKWIGIPVFAAVMFGVFYISQSTVGTWIADWLVGWIEAFQGWAAGLTEQA
                     NPFWQALLVDGIIGGVGAVVGFLPLVMVMYFLIALLEDCGYMARATVVLDPLFKRVGL
                     SGKSVIPMVIGTGCAIPGIMACRTIRNERERRATAMLTPFMPCGAKLPVIALFAGAFF
                     ADASWVGPAMYLAGILLIFLGALLVNKITGYKYRKSFFIIELPEYKIPSLKRAVLSML
                     SRGKAYIVKAGTIILVCNTAVQIMQSFNWQLQIVEEGMEHTSILASLAAPFAVLLIPL
                     GFGVWQLAAAAITGFIAKENVVGTLAVVYGLTNFIDTEELALVGGGNEVAMVMGLTKV
                     AALAYLTFNLFTPPCFAALGAMNSEMQNKKWLWGGIALQLCTGYTVAFFIYQIGSLIT
                     TGAVGAGFVPGLAAVAAFAAGLAVLIRKKEKAFGAEYRLHA"
     gene            complement(4477..4550)
                     /locus_tag="ACZPCR_11110"
     tRNA            complement(4477..4550)
                     /locus_tag="ACZPCR_11110"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4514..4516),aa:Met,seq:cat)
     gene            complement(4565..4637)
                     /locus_tag="ACZPCR_11115"
     tRNA            complement(4565..4637)
                     /locus_tag="ACZPCR_11115"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4602..4604),aa:Val,seq:tac)
     gene            4807..5760
                     /locus_tag="ACZPCR_11120"
     CDS             4807..5760
                     /locus_tag="ACZPCR_11120"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001727 - lipid kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol/lipid kinase family protein"
                     /protein_id="HIR1231448.1"
                     /translation="MYCFIINPCSGCGRGLRVWKKIEQQLMCEGAEYRAFMAEGPGQA
                     SKIAGELTKGRGTGQTIVVVGADDTFGEVLDGLNLGENVTLGYIPAGSRKDLARSLRL
                     PLNSRRCLRRIFSPRQYRCLDYGLLTYGEDSMRHRRFAVSAGMGLTAAACKSAPEGIS
                     AAEPGIFKNRFGAARRLFRRAQYLVGGIWQLIKAKPSKGYILLDRTRKVEFNHMYFVS
                     AHIHPSEGGGFYFAPEADPGDGKLEICVASHSSKLRLIPMLIRSRLPRFVKRKGVRVY
                     ECREARIHMDRPAPIHTDGEICRFQSDLEIQCIEKKIRVIV"
     gene            5812..6363
                     /gene="ispF"
                     /locus_tag="ACZPCR_11125"
     CDS             5812..6363
                     /gene="ispF"
                     /locus_tag="ACZPCR_11125"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013271993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008685 - 2-C-methyl-D-erythritol
                     2,4-cyclodiphosphate synthase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HIR1231449.1"
                     /translation="MRIGQGYDVHKLTEGRDLILGGVKIPYEKGLLGHSDADVLVHAV
                     MDALLGAAALGDIGQHFPDTDPAYKGASSIELLKQVGRILSEHNYLIENIDATVIAQR
                     PKLLPYRPQMAENIARALGLDPGRVSVKATTEEGLGFTGTGQGISAQAITLLTEVDNY
                     CYDREMTAQTGCGGCCPGGGCGR"
     gene            6432..7841
                     /gene="cysS"
                     /locus_tag="ACZPCR_11130"
     CDS             6432..7841
                     /gene="cysS"
                     /locus_tag="ACZPCR_11130"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007709018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HIR1231450.1"
                     /translation="MKIFNTLSRRKEEFVPLEEGKVKMYVCGPTVYNFIHIGNARPMI
                     VFDTVRRYFEYKGYDINYVSNFTDVDDKIIKKAIEEGVDAQTISERYIAECKKDMEMM
                     NVKPATVHPKATEEICGMQEMIETLIEKGHAYTAKDGTVYFRTKSFKGYGKLSHKNLE
                     DLQSGFREIKVTGEEDKEDPTDFVLWKPKKDGEPFWESPWCQGRPGWHIECSVMSKKY
                     LGESIDIHAGGEDLVFPHHENEIAQSEAANGKPFATYWMHNAFLNIDNKKMSKSLGNF
                     RTVREISEQYDLQVLRFFMLSAHYRSPLNFSAELMEASRNGLERILTGVERLNDLLSS
                     ASEKELSGEEKKNLETKAELVKKFEAAMDDDFNTADAISAVFELVKLSNSTISEESAK
                     AYLSELKKEIETLCGVLGIITEKKKEALDSEIEAMIEARQQARKSKNFALADEIRGKL
                     LDMGIVLEDTREGVKWKRV"
     gene            7826..8338
                     /locus_tag="ACZPCR_11135"
     CDS             7826..8338
                     /locus_tag="ACZPCR_11135"
                     /EC_number="3.1.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002593612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HIR1231451.1"
                     /translation="MEESLGCFKEALRLKEADPASYSPLVLAYLGDAVYELAIRTLVV
                     NEGNRQVNKMHKESASLVKAGTQMEFLLAIEDELTEEEKSVYRRGRNAKSVTMAKHAT
                     MKEYRTATGFEALIGYLYLQGRLERLAKLLGLGLDRLGKWKDGEGAKPLKNAEDSRAQ
                     EPENTEQAGE"
     gene            8343..9086
                     /gene="rlmB"
                     /locus_tag="ACZPCR_11140"
     CDS             8343..9086
                     /gene="rlmB"
                     /locus_tag="ACZPCR_11140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007867037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HIR1231452.1"
                     /translation="MRYEELTIEGRNAVLEAFRSGKTIDKLYVLDGCQDGPVKSITRE
                     ARKQDTIINYVTKERLDQLSETGKHQGVIAHAAAYKYAEVEDMLKAAQEKGEPPFLFI
                     LDGIEDPHNLGAIIRTANLAGAHGVIIPKRRAVGLTAVVAKTSAGALNYTPVAKVTNL
                     AATIEELKEKGLWFVCADMGGESMYRLNLKGPIGLVIGNEGEGVSRLVREKCDMIASI
                     PMKGDIDSLNASVAAGILAYEIVRQRVMG"
BASE COUNT         2497 a         1950 c         2721 g         2090 t
ORIGIN      
        1 cgaaattatt aaggcgcagt tagaaaaact ggacgagaag attgttaaga tagagaaaac
       61 actgaaaggc ttaaaggcag agaggaaaaa attagaggag gagttaaagt cctctgagct
      121 gacggcgatt gccgagttta tctcggaaag cggcgtgact gtagaacagt taaagagcat
      181 gattgagaag gaaaatctga acgcagctga gtaggcgcag gagaaacgaa atgatttaaa
      241 aatatccatt tgagtgcttt gccgccttaa atgggtattt tttatttcgc tggaattctt
      301 tcttacttgg gaaagaactt gcggcgacaa gggggggaag atggatattc aaaagaaaaa
      361 acgcgtttat cagacgcgct tcttcatttt tacagcagtc agtgcagggc ttttgtggtt
      421 ttacatccgg tcagagaggg agtaccagac agggccgcac agtatttggc agctgcttcc
      481 atatttctgg ttcggcttga ccattgcgtg ggcggttctg gtattttatt atcagaagct
      541 gacgctgaaa agccagaaca cagatgcttt aactggagga ccgaatgaga gagccttccg
      601 tatggccgtt gaaaagagaa tgcgggcggg cggtgaagcc tttgtttttg cagtgattga
      661 tattaagaag ttcagcagaa ttgaaaactg gtatgatcat gcggtaggcg atcaggtgtt
      721 gaagagagta tatgaagcgc tgcgctcctg cctgaaggaa aacgaggtgc tgtgcagagc
      781 cagcgcagat cagtattatc ttcttttgga ggagacggat ccggaattgt tgttaaaacg
      841 gctgctggcg ctggacgatt ccgtatattt tctggaggat ctgccgatta aggaaaaatt
      901 atttctgtct atgggagcgt accagactgc aggggagcag gatacctttg cccacgcgct
      961 ggattgcgcc aattactgcc ggaaggaaag ccctgactgc cacgatcgga acagccatct
     1021 ggaaatctac ggctatacgt tccaggacca ccgggacaga gaccgcagat atcacgaaca
     1081 ggcggaggag gctctgaagg caggacactt ccacatgtat cttcagccga aatacgagct
     1141 ggagcatgag agtctggctg gagcggaggc cctgttccgg tggattgatc cggagaaggg
     1201 aatgcttcct ctgggagaat ttatgcctct ttttgagaaa aatggctttg tgcgccaaat
     1261 tgactatttc attttcgaat ctgccctgaa gctgattcag aaatggctgg acagcggtgt
     1321 gaaaccggta aagatatcgg tcaacctgtc aaaatcccat ttcagcaacc gggagttttt
     1381 cgagaacaaa ttcctgccca tctatgaaaa gtatcaggtt cccaaggagc ttctggaatt
     1441 tgagatttcc gagaacacca tgttagacgg acaggggatg ctgatcggct ttgtccagaa
     1501 gttaaaggac atgggatttt cctgttccat ggacgacttt ggcagcggct attcgtcctt
     1561 aaataccctg aaaagtattc cagtttccac ggttaagctg gacggcagga tgtttgagga
     1621 aacagaaaag gaacggggaa agatagtgag caaaggcatg atccggattg ccagagaact
     1681 gcagattgag gtggtggcgg aaggcgtgga gaccagagag tatgtggatt tcttaaaaga
     1741 gcagaagtgc gatttggttc agggctacta ttttggaaaa ccaatgccag ccgaagaatt
     1801 tgagaagctg atgcagggct gaatggccgc tgtttatgaa acgaaggctc tgtgcataaa
     1861 aatgtgcaga gctttttctc tgcccaaaat cagtgcagac atatactgca aaaatgaaaa
     1921 acaggttgac aaacagaaaa gattagttta aactaactaa agtaagttat aactaaccga
     1981 agcgaataga ataaaaatag aaagaacgga gtggatcgca gatatgaacc tatgggaagc
     2041 gaaagaggga gaggaatata ttataaaaga gattgccaca gatgacgagg agctgaacgc
     2101 ttttttgttt tccctcgggt gctacagcgg agaaccgatt actgtaatcg cccgccgaaa
     2161 aggaggatgc gtggtatctg taaaagatgg cagatataac atggatactg atttagcgca
     2221 ggctatttca atctaggata gagtgatttc ggtcactatt ttttatgaac ataggttagt
     2281 ttgcgttaac caaaaccaca aaggaggagc agatgagtga tgagaattgc attgacagga
     2341 aatcccaata gcggaaagac gaccatgtac aacgcgctca cagggagaaa tgagcgcgtt
     2401 ggaaactggg ctggcgttac ggtagagaag aaggaaagcc cgattaaaaa agcttatttt
     2461 gacggggagg aggagctgat tgcggtagat ttgccgggag cttattctat gtcgcctttt
     2521 acttctgagg agagtattac cagcgcctat gtgaaaaatg aaaatcctga tgtgattatt
     2581 aatattgtgg atgcggcgaa tttaagcaga agcttatttt tcaccacaca gcttttggaa
     2641 ctggggattc cggtggtagt cgctctcaat aaaagcgata tcacagaaaa gaaaaagacg
     2701 gaaattgacg taaaaagtct gtcccagagg ctgggctgtc ctgttgtcca gaccatttcc
     2761 acatcttctg gccgggacgg cctgaaggag gcggttaatc aggcggctgc cttaaaaggg
     2821 cggggacaga cggctcctta ccaccaggag gacatcgatc tgcaggataa agcggcagtg
     2881 gaagcggcag accgggcgcg ctttgaattt gtaaacggaa ttgtgaaagc agtagaaacg
     2941 agaagggttt ttacaaagga tagaaataaa caggacagaa ttgacgctgt actcaccagc
     3001 aaatggattg gaattcctgt ttttgccgcc gtcatgttcg gggtatttta catatcacag
     3061 tctaccgtcg gaacgtggat tgcggactgg ctggtgggct ggattgaggc gttccagggc
     3121 tgggctgcag gcctgacaga acaggccaat ccattttggc aggcgctttt agtggacgga
     3181 atcatcggag gagtaggagc ggtagtcggc ttcctgcctc tggtaatggt tatgtatttc
     3241 ctgattgcgc ttttagagga ctgcggctat atggcccgcg ctacggttgt tctggatccg
     3301 ctttttaaac gggtgggcct ttctggaaaa tctgtgattc caatggtgat aggtactgga
     3361 tgcgcgattc cgggcattat ggcgtgccgg acgatccgca atgaaaggga gagacgggca
     3421 acagccatgc tgacgccgtt tatgccatgc ggagcaaaac ttccggtcat tgccctattt
     3481 gccggagcgt tctttgcaga cgcttcctgg gttggaccgg ccatgtatct ggctggcatt
     3541 ctgctgattt ttctgggagc tttgctggtc aataaaatta cgggatataa gtacaggaaa
     3601 tctttcttta tcattgagct gccggaatac aaaattccaa gcctgaagcg cgcggtgctt
     3661 tccatgctgt cccgcggcaa agcttatatt gtgaaggcgg gcacgattat tcttgtctgc
     3721 aatacagcag tacagattat gcagagcttc aactggcagc tccagatagt ggaggagggg
     3781 atggagcata cttccattct ggcgtccctt gccgctccat ttgcagtgct gctcattccc
     3841 ctgggatttg gagtatggca gcttgcggcg gcagcgatta caggctttat tgcgaaggaa
     3901 aatgtggtcg gcacactggc ggtcgtatac gggctgacta actttatcga cacagaggag
     3961 ctggctctgg tcggcggagg aaatgaagtg gcgatggtta tggggcttac gaaagtggcg
     4021 gccctcgctt atctgacatt taatctcttt acgccgccct gcttcgcggc gcttggagcc
     4081 atgaattctg aaatgcagaa taaaaaatgg ctgtggggcg gcatcgcact gcagctgtgc
     4141 accggctaca cggtcgcgtt tttcatctat cagataggtt cccttatcac aacaggagca
     4201 gttggagccg gctttgtgcc gggactggca gctgtggcgg cgttcgctgc gggattggcc
     4261 gtgttaatca ggaaaaagga aaaggcattt ggcgcagaat accgtctgca cgcataggca
     4321 taggatcaga aacagcctgc atctgggaag ggatgcaggc tgtttccttc tgaacagata
     4381 tgagccggcg caccaaaggc agtgcccctt gtgcgctggt gctgacagct gttttggaac
     4441 aacaaaaaaa cccttgaaca atcaagggtt tcaaagtagc ggaagggaga ttcgaactct
     4501 cgacactacg ggtatgaacc gtatgctcta gccaactgag ctattccgcc atattccata
     4561 taaatggggc ctatagggct cgaacctatg accctctgct tgtaaggcag atgctctccc
     4621 agctgagcta agaccccatt tcgctgtcgc tcatttgcga ctgcttagac agtataatat
     4681 actttccaga gaatgtcaat actttatttt aaatttttta atagaaattt tcttagattt
     4741 ttatttcata tatgttataa tatcgtcaga tattctgaac tgataaagaa atagacggag
     4801 gctgttatgt attgttttat cataaatccc tgctccggct gcggacgtgg tctcagggta
     4861 tggaaaaaaa tagaacagca gcttatgtgt gaaggggcag agtaccgggc atttatggcg
     4921 gaggggcccg gacaggcgtc gaaaatagcg ggggagctga caaagggaag aggaacagga
     4981 cagacaatag tagtagtggg ggcggacgat accttcggag aggtgctgga cggcctgaat
     5041 ctgggagaga acgtgacgtt aggttatatt ccggcaggca gcaggaagga tctggcgagg
     5101 agcctgcgtc ttcccctgaa ttccaggaga tgcctgcgca gaattttctc tcccagacag
     5161 tatcgctgcc tggattacgg gctgctcacc tatggagagg attcgatgcg ccaccgccgg
     5221 tttgcagtga gcgcaggcat ggggctgact gcagcggcgt gtaagagcgc gccggagggc
     5281 ataagtgctg cagagccggg gatttttaaa aaccggtttg gagctgcccg ccgtctgttc
     5341 aggagagctc aatatttagt gggaggaatc tggcagctta taaaggcgaa gccgtctaag
     5401 ggatatatcc tgttggacag aacgcggaag gtggagttta accacatgta ctttgtttcc
     5461 gcccacattc atccatcaga gggcggaggc ttttattttg cccctgaggc ggatccgggg
     5521 gacggaaaac tggagatttg cgtggcaagc cattcgtcca agctgcgcct gatccctatg
     5581 ctgatacgga gcaggcttcc gcgctttgtc aagagaaagg gagtccgcgt ctatgagtgc
     5641 agggaagcca ggatccacat ggatcgcccg gcgccgatcc acacagacgg ggagatctgc
     5701 cgcttccaga gcgatctgga gattcagtgt attgagaaaa aaataagagt gattgtataa
     5761 aacgcttaaa ataaagcgga tgtatcagta tagaaatcgg aggaaacaga tatgagaatc
     5821 ggacagggat atgatgtcca caaattaacg gagggccgcg acctgatttt aggcggcgtg
     5881 aagattccat atgaaaaggg gcttctgggc cattcggacg cggacgtgct ggttcatgcg
     5941 gtgatggacg cccttttggg ggccgccgcg ctgggagata tcggccagca ttttcccgat
     6001 acggatccgg cctataaagg cgcgtccagc attgaactgt taaaacaggt gggacgcatt
     6061 ctgtcagagc ataattatct gatagagaat atcgacgcca cagtgattgc ccagagaccg
     6121 aagcttctgc cctacaggcc gcagatggcg gagaatatcg cccgcgcact ggggcttgat
     6181 cctggcagag tcagcgtaaa ggccaccacg gaggaggggc ttggatttac cggcacaggc
     6241 cagggaattt ccgctcaggc cattacactg ttgacggaag tggacaacta ttgttatgat
     6301 agagaaatga cggcgcagac cgggtgcgga ggctgctgcc ccggcggggg ctgcggacgt
     6361 taaatacctt atccggctga tgcacggaaa agctgcgaat gaaacaagag attttgtaga
     6421 ggagaaacgc tatgaaaatt tttaatacgc tgtccagacg gaaggaagag tttgttccgt
     6481 tggaggaagg caaggtaaag atgtatgtgt gcggtccgac cgtatacaat tttatccaca
     6541 ttggaaatgc aagacctatg attgtctttg atacagtcag acggtatttt gagtacaaag
     6601 gctatgacat caactatgtt tccaatttca cagatgtaga cgacaagatt atcaagaagg
     6661 ccatcgagga gggcgtggac gcccagacca tttccgagcg ctatattgcc gagtgcaaaa
     6721 aggatatgga aatgatgaac gtaaagcctg ctaccgtaca tcccaaggca acggaggaaa
     6781 tctgcggaat gcaggagatg atcgagactc tgattgagaa ggggcatgcc tatacggcga
     6841 aggacggaac cgtctacttc cgcaccaagt ccttcaaggg atacggaaag ctgtcccaca
     6901 agaatctgga ggatctgcag tccggcttcc gcgagattaa ggtaacggga gaggaggaca
     6961 aggaggatcc gactgatttc gtgctctgga agccgaaaaa ggacggagag ccattctggg
     7021 agtcaccctg gtgccaggga cgtccgggct ggcatattga gtgctctgtt atgtccaaga
     7081 agtatctggg cgagtccatt gatatccacg caggcggaga agatctggta ttcccacacc
     7141 acgagaacga gatcgcccag agcgaggcgg ccaatggaaa gccgtttgcg acctactgga
     7201 tgcacaacgc atttttaaat attgacaata agaagatgtc taaatccctg ggcaacttcc
     7261 gcacagtccg ggagatttcc gagcagtatg atttacaggt gcttcgcttc ttcatgctga
     7321 gcgcccacta cagaagcccg ttaaacttca gcgcggagct gatggaggct tccagaaacg
     7381 gtctggagag aatcctcaca ggcgtagagc gcttaaacga tctgttatcc agcgcgtccg
     7441 agaaggagtt gtccggtgaa gagaagaaga acctggagac aaaggcggag ctggtgaaga
     7501 agttcgaggc cgccatggac gacgatttca atacagccga cgctatttcc gctgtgtttg
     7561 agctggtgaa gctgagcaac tctaccattt cagaggagag cgcaaaggct tatctgtcag
     7621 agctcaagaa agagatcgaa actctctgcg gcgttctggg aattatcaca gagaagaaga
     7681 aagaggccct ggacagcgag atcgaggcca tgattgaagc cagacagcag gccagaaagt
     7741 ctaagaattt cgcgctggca gacgagatcc gcggaaagct tctcgatatg ggaatcgtcc
     7801 tggaggacac cagagagggc gttaaatgga agagagttta ggctgtttta aggaggctct
     7861 gaggctcaag gaggcggatc ccgcctccta ttctcctctt gtgctggcat atctgggaga
     7921 cgcggtatat gagctggcga tccgcacgct ggtggtcaac gagggaaacc gccaggtgaa
     7981 taagatgcac aaagagagcg cttctctggt gaaggcgggg acccagatgg agtttctgct
     8041 tgccatagag gacgagctga cggaggaaga gaagtccgtc taccgccggg gcagaaacgc
     8101 caagtctgtg accatggcca agcatgccac catgaaggaa tacaggacgg ctacaggctt
     8161 cgaggcgctg atcggctatc tgtatctgca gggaaggctg gagcggctgg cgaagcttct
     8221 gggcctgggc ctggaccgcc tgggaaaatg gaaagacggg gaaggcgcga agcctttgaa
     8281 aaacgctgaa gacagccggg cacaggagcc ggaaaacaca gaacaggcag gagaataaga
     8341 aaatgagata cgaggaactt accatagagg gacgaaacgc cgtgctggag gctttccgct
     8401 ccggaaagac tatcgacaag ctgtacgtgc tggacggctg tcaggacggc ccggtgaaga
     8461 gcatcaccag agaggccaga aagcaggaca cgatcattaa ctatgtgacg aaggagcgcc
     8521 tggatcagct gtctgagacc ggaaaacatc agggagtcat cgcccatgcc gccgcctata
     8581 agtacgcgga ggtggaggat atgctgaagg ccgcccagga gaagggagag ccgccgtttc
     8641 tgtttattct ggacggcatt gaggatcccc acaatctggg ggcgattata agaactgcca
     8701 atctggcggg cgcccacggc gtgatcattc caaagagaag ggcagtgggt ctgactgccg
     8761 tagtggcgaa aacctctgcc ggagctttga attatacgcc ggtggccaag gtgacgaacc
     8821 ttgccgccac tatcgaggaa ctgaaggaaa aggggctttg gtttgtgtgc gccgatatgg
     8881 gcggcgagag catgtacaga ctgaacttaa aaggccctat tggccttgtc atcggaaacg
     8941 agggcgaggg cgtcagccgt ctggtgaggg aaaaatgcga tatgatcgcg tccattccca
     9001 tgaagggaga catcgactcc ctgaacgctt ctgtggcagc cgggatcctg gcctacgaga
     9061 tcgtgcgcca gagagtgatg ggataatacg aatatataat agagaagagg cggattttcc
     9121 aggcttgaga aagccaggga gaatccgcct ttttagctga aatttttaga agctgcagcg
     9181 ccatttccta tcataaggat aatggtttta atatgcgggt aacaggactt gaacctgcac
     9241 ggtctcccac cagaacct
//
LOCUS       DBMDUW010000078         9248 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_3491_length_9248_cov_3.231442, whole genome shotgun sequence.
ACCESSION   DBMDUW010000078 DBMDUW010000000
VERSION     DBMDUW010000078.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 9248)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 9248)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9248
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3491_length_9248_cov_3.231442"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            309..2075
                     /locus_tag="ACZPCR_11145"
     CDS             309..2075
                     /locus_tag="ACZPCR_11145"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231453.1"
                     /translation="MKRYRAVRGKEAPWQTKAVKSAVHLFRGTFDIEDSGTESSETEY
                     AEIENSEEEAQAAEKEQPEDTARICLPGFGLPVKNPAIREKTLLWKNLKRVQRENGIT
                     ESRPIREDRLDFCMEMPEGEGRSFVLFRTILELNQAYGLLKFIVAVPSVAERLKLAEA
                     ARKFSGCFLKLGYPGLSDCCFSCRGENLREVSTRLVESERLSICIMNIQTFNRGTNRL
                     RAADEYGQVLWEDIRAVRPVVILDEPGADSGVSELQESSGAFQALEGLNPLFTLRFQS
                     KAGSAENRIFSLTREAALRQGAVKTCFLKNPKSQEGEEGLAEEKIRLAVRLHIEKQLE
                     LLRAGRRVKCLTLFFTAASSHERERLLTLFEQAYQEILGEYDGQIRQLGEEALSVFCR
                     EPEKARKVFLGIDKSGRERELDGWEKKDAGSFRKRLLEDVNRGIGEILRESETLSSFE
                     RQEAFLFAHPALRRGCGSRNLFVICCLDSGVPEASLRKKAACGQWLSEDQEGNQFSGD
                     ETESLWVIGEGIPEDPYWSCGKETACSEPFQKALESLERIKKEPAFAAPSGLSRLTEE
                     ERNELLSCMDRAEELLKKAAIL"
     gene            2187..2966
                     /gene="udp"
                     /locus_tag="ACZPCR_11150"
     CDS             2187..2966
                     /gene="udp"
                     /locus_tag="ACZPCR_11150"
                     /EC_number="2.4.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007889718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine phosphorylase"
                     /protein_id="HIR1231454.1"
                     /translation="MQNYSGEVGLMYHLQIRKGDVGRYVILPGDPKRCQKIAQFFDDP
                     VLVADSREYVTYTGTLDGEKVSVTSTGIGGPSASIAMEELVQCGADTFVRVGTCGGID
                     LNVKGGDIVIATGAVRMEGTSKEYAPIEFPAVADLEVANALAAAAKKLNMPYHTGVVQ
                     CKDAFYGQHDPERMPVSYELLNKWEAWKRLGCKASEMESAALFIVAAHLGVRCGSDFL
                     VVGNQEREKLGMENQICHDTEAPIRVAVEAIRSLIKADREK"
     gene            3049..4251
                     /locus_tag="ACZPCR_11155"
     CDS             3049..4251
                     /locus_tag="ACZPCR_11155"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - metabolic compound salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HIR1231455.1"
                     /translation="MGQYKKYKRVFTIVLDSLGVGAMEDSAQYGDVGVDTLGHIAEYA
                     ESLEIPNLRKLGMANLHPMKQNAPVDRPMGKYMKMREKSCGKDTMTGHWEMMGLHITK
                     PFQTFTDTGFPKELIDELEKRTGRTIIGNKSASGTEILDELAEEEIATGHLIVYTSAD
                     SVLQICGNEETMGLETLYRYCEIARELTMRDEWKVGRVIARPYVGRKKGEFKRTANRH
                     DYALKPYGQTALNAMKDAGYDVISVGKIFDIFDGEGLTESNKSKSSVHGMEQTIEIAE
                     RDFTGLCFVNLVDFDALWGHRRDVKGYAEELEKFDEKLGELLPLLKDDDLLILTADHG
                     NDPTYTGTDHTREKVPFIAWSPSMACGGEMEENDTFAVVGATIADNFGVAMPEGTIGS
                     SRLEEIEK"
     gene            4276..4926
                     /gene="deoC"
                     /locus_tag="ACZPCR_11160"
     CDS             4276..4926
                     /gene="deoC"
                     /locus_tag="ACZPCR_11160"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006567558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HIR1231456.1"
                     /translation="MEKQEILKRLDHTLLQQTAVWEQIKVLCDEGMEYGTASVCIPPS
                     FVKRAKEYVGDRLAVCTVIGFPNGYMTTAAKVFETEDAVKNGADEIDMVINIGMVKEK
                     DYDGVLAEIRGIKEACRGKLLKVIIETCLLTEEEKVELCRVVTESGAEYIKTSTGFST
                     GGATFEDVALMRKHVGSGVKVKAAGGIASVSDAEKFIELGADRLGTSRLIKLLEAE"
     gene            5114..5497
                     /locus_tag="ACZPCR_11165"
     CDS             5114..5497
                     /locus_tag="ACZPCR_11165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HIR1231457.1"
                     /translation="MEWKITDDRPIWMQLSEQLSAQIAAGTYGPGERLPSVREFAAQA
                     GVNPNTMQRAMADLESQGLITTNRTAGRCVTQDMERIKQVRNSQAREQAIRFLEQMGS
                     LGYTREEIKHVLEELFDTMKEEGTV"
     gene            5494..6231
                     /locus_tag="ACZPCR_11170"
     CDS             5494..6231
                     /locus_tag="ACZPCR_11170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1231458.1"
                     /translation="MSREILVCKGLGKKFGTRYALKDVDLTIESGKIIGLLGPNGSGK
                     TTLMKLANGLLKPEEGWLSIDGNEPGVETKAVVSYLPDQTYFADWMRVSDLLNMFSDF
                     YRDFDRQRAAAMLKDLDISEKARMKSLSKGNKEKVQLILVMSRNARLYLLDEPIGGVD
                     PAAREYILQTILTNYSEDASVIISTHLIADVEKVLDEAVFLKEGRLVRHSSVDEIRET
                     EGKSVDHLFREIFAVQGSGNGSGDGDR"
     gene            6247..7068
                     /locus_tag="ACZPCR_11175"
     CDS             6247..7068
                     /locus_tag="ACZPCR_11175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231459.1"
                     /translation="MFGKLLKYEWKAMMKTMLPIYGATMVLAAVNGFLFQSILGGWMD
                     RSALFSTMQTTAITLYMLILMIMGVFTAVMIVQRFYKGLLRQEGYLMFALPVKTWKLI
                     FSKACVSFAVSVLSMIVGILSIGLFGGLDFFRALYELPILMWAFMQEGYEANPEAFAY
                     MVLFALEVLAGLAVAAFASIYELYFSMALGQLSRNHKVIWSVFWFMAVSTAMNFVAML
                     LVGNGMDLMDFAETAEDMTMRLHMAGLGMLAVQAVSLVLLMFGTGYVLDRKLNLE"
     gene            complement(7149..9035)
                     /locus_tag="ACZPCR_11180"
     CDS             complement(7149..9035)
                     /locus_tag="ACZPCR_11180"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: protein motif:HMM:TIGR00254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase domain-containing protein"
                     /protein_id="HIR1231460.1"
                     /translation="MEKSRISGMRSGSKPLIVITTAIILSIIIMISLFIIYFNKVYSS
                     VLEKDMEQIEWTSHYVTKLIHTEIQHSVDILQASEEIFHASEGTGQKGVQGSLQEIRE
                     GLHFEKIGVASLDGSSIDDTGVIRKLADPRLFESILNDQSYISNVLTASDDMVIAVPL
                     HHGGQVVGALWGYLSISSIAESIEMDKEMHRYFQIVDDNGNYIIHSGNVYAFAEDMNI
                     WEEMKRYTFADGVTVESIHQDVINGESGYFYFSFQNQGRYVTYEPLGINNWYVFSVVV
                     ESFLKDYAENIEHIFVWLLAGLSVCVVAVFLIIGHFIRRVMKTIQIQNQEIQVKNSLL
                     STILKKTQDIPFEINLEQNLLFLYHQHPNESGLDYQVISDFTPDYLLKAGLIREEGYD
                     SYKTFYETVMSGGTAEPIVLDIWLNHRWDCNKIHALTVDREHVIGFLEDYNEQMKSER
                     TIEAINLKNQIDPLTGLYNRETFIQKTEEILRLPDSNSPGVSALFLLDLDHFKEVNDQ
                     LGHMAGDQVLQETGLILKSVVRSTDLSGRLGGDEFVLFIQNAADHRGLERCAEKLVSA
                     LNRTFSSTEYSVTVSASIGIVPVQGGESFAQLYEAADKALYEVKRTRRNGYQFAASVP
                     KPVL"
BASE COUNT         2471 a         1937 c         2670 g         2170 t
ORIGIN      
        1 cttgaccgct tgaccaacag gccttctatt ttgtttttct gtcgctcgct gtcgacttag
       61 acagtatatc acacttccga aaaaatgcaa gcactttttt gattttttta aattttaaaa
      121 attttatttt tttcctaatt ttttaaaagg tgtaaaaagc gtggatacag atttcaattt
      181 ttccccggaa atggtataat tagtttcaaa cgcagctaaa atatttggcc tctgccatat
      241 cattcaatgg gatgccgcgc cggctcaggg aagatgctgt taagtgactg gggaagggag
      301 gagatagcat gaaacgatac agggcggtga gaggaaagga agccccctgg cagacaaagg
      361 cggtaaaatc ggcggttcat ctgttccggg gaacgtttga tatagaagat tcaggaacgg
      421 agtcttcaga aacagaatat gcagagatag aaaattcgga agaagaggcg caggcagcag
      481 aaaaagaaca gccggaggat accgccagga tctgccttcc gggatttgga cttccggtga
      541 aaaatcctgc cataagggag aaaacccttc tgtggaaaaa tctgaaacga gttcagcggg
      601 agaatggaat tactgagagc agaccgatta gggaggacag actggacttc tgcatggaga
      661 tgccggaggg agaaggacgc agctttgtgc tttttcggac gattttagag ctgaaccaag
      721 cttatggtct tctgaaattt attgtagcgg ttccctctgt ggcggagagg cttaaactgg
      781 cggaagcagc gagaaaattt tccggatgct ttttgaagct ggggtatccc ggcctttccg
      841 actgctgttt ttcctgccgg ggagagaatc tcagggaagt cagcacgcgg ttagtagagt
      901 cggagaggct ttccatctgc attatgaata ttcagacctt taacaggggg acgaaccggc
      961 tgagagcggc cgacgagtac ggacaggtgc tgtgggaaga tataagagcg gtaaggcctg
     1021 tggtgattct ggacgaacct ggagcggaca gcggagtttc ggagctgcag gaaagctccg
     1081 gagcattcca ggccttggaa ggattaaatc ccctgtttac cctgcgcttt cagtcaaagg
     1141 cgggatctgc ggaaaacagg attttcagtc tgacaaggga agctgcactg cggcagggag
     1201 cggtgaagac atgcttttta aagaacccca aatctcagga gggggaggag ggactggctg
     1261 aagagaagat ccgcctggcc gtaaggcttc atattgaaaa gcagctggag cttttaagag
     1321 cagggcggcg cgtaaaatgc ctgactttat tttttacagc ggcttccagc catgagagag
     1381 agcggctgct gacgcttttt gaacaggctt atcaggagat tctgggagag tacgacggcc
     1441 agatccgcca gctgggtgaa gaggcgcttt ctgtattctg ccgggagccg gaaaaggcga
     1501 ggaaggtatt tctggggata gataagagcg gacgtgagcg cgagctggac ggctgggaga
     1561 aaaaggacgc cggaagcttt cgaaaacgcc tgctggagga cgtgaaccgc ggaatcggag
     1621 aaattctgag agaaagcgaa acgctctctt cttttgaacg ccaggaagcg tttctcttcg
     1681 cccatccggc gctgcgaaga ggctgcggca gcagaaacct gtttgtgatt tgctgtctgg
     1741 attccggggt gccggaggcg tccctgagaa aaaaggcagc ctgcggacag tggctgtcag
     1801 aggatcagga ggggaatcag ttttccggtg atgagacaga gagtctctgg gtgattggag
     1861 agggaattcc ggaggatcct tactggagct gcgggaagga gactgcatgt tcagagccgt
     1921 ttcagaaggc ccttgaatcg ttagagagga taaagaagga gccggctttc gcagcgcctt
     1981 caggactttc gcggcttaca gaggaagaga gaaacgagct gttgtcctgt atggacagag
     2041 cggaggagct tctgaaaaag gctgcaatcc tctagaaaaa cgtgaaagag cagagaaaat
     2101 ccgggaaaga atgaacatgc aggcagaaat gcattgccaa acacaagtgt tttcatatac
     2161 aataggaaaa tcgaaaggag aagcgtatgc agaattattc aggtgaagtg ggtttaatgt
     2221 atcatttaca gatcagaaaa ggcgacgtgg gccggtatgt gatcctgccg ggagatccga
     2281 aacggtgcca gaagatcgcc cagttttttg acgatccggt gctggtggct gacagcaggg
     2341 agtatgtgac ctatactgga acgctggacg gggagaaggt aagcgtgact tccacgggaa
     2401 tcggcggccc ttccgcctcc attgccatgg aagagctggt tcagtgcgga gccgacacct
     2461 ttgtccgggt aggaacctgc ggaggaatcg atctgaatgt aaagggaggc gatattgtca
     2521 tcgctacagg cgcggtccgc atggagggaa ccagcaagga gtacgcgcct atcgaatttc
     2581 cggcagtggc ggatctggag gtggccaacg ctctggcagc agcggcaaag aaattgaata
     2641 tgccttatca cacaggcgta gtgcagtgta aggacgcctt ttacggacag cacgatccgg
     2701 agcggatgcc agtcagctac gagctgttaa ataagtggga agcctggaag cgcctgggct
     2761 gcaaagcttc tgagatggag tcggccgccc tctttattgt agccgctcat ctgggcgtgc
     2821 gctgcggttc tgatttcctg gtggtgggaa atcaggagag ggagaagctg gggatggaaa
     2881 atcagatctg ccacgatacg gaggcgccta tccgcgtggc ggtggaggcg atccgcagcc
     2941 tgattaaggc cgacagggag aaatagcaga aaaaggcaga tcagccgttc agagtatgaa
     3001 aaagccggaa aagacagaaa aaagagacag aaggaggcag aaattaaaat gggacagtat
     3061 aagaaataca agcgtgtttt tacaatcgta ttagattccc tgggagtagg agccatggag
     3121 gattccgccc agtatggaga cgtgggggtg gataccctgg gacatattgc ggagtatgca
     3181 gagagccttg agatccccaa tctcaggaag ctgggcatgg caaatctcca tccgatgaag
     3241 cagaacgcgc cggtggatcg ccctatggga aaatacatga aaatgaggga gaaaagctgc
     3301 gggaaggaca cgatgaccgg ccactgggag atgatgggac ttcacattac caagccgttt
     3361 cagaccttca cagacacagg attccccaaa gagctgatcg acgagctgga gaagcggacc
     3421 ggcaggacaa ttatcggaaa taagagcgcc agcggaacag agatcttaga cgagctggcg
     3481 gaggaggaga ttgccacagg ccatctgatc gtctatacat cggcagactc ggtgcttcag
     3541 atctgcggaa atgaggagac tatgggactg gagaccctgt accgctactg cgagattgcc
     3601 agagaactga ccatgcggga cgagtggaag gtgggacgcg tcattgcaag gccttatgtg
     3661 ggcaggaaaa agggcgagtt caagcgcacg gccaaccgcc atgactacgc tttaaagcct
     3721 tatggccaga cggcgttaaa cgccatgaag gacgctggat acgatgtgat ttcagtggga
     3781 aaaattttcg atatttttga cggagaggga ctgacggaat ccaacaagtc caagagctct
     3841 gtccacggca tggagcagac cattgagatt gcagagagag attttacagg cctctgcttc
     3901 gtaaacctgg tggatttcga cgctctgtgg ggccacagaa gagacgtgaa gggctacgca
     3961 gaggagcttg agaagttcga cgagaagctg ggagagctgc ttcctcttct gaaagatgac
     4021 gatctgctga ttctgacggc agatcacggc aatgatccga cttacacagg aacggatcac
     4081 accagagaaa aggttccctt tatcgcctgg tctccgtcca tggcctgcgg cggcgagatg
     4141 gaggagaacg atacctttgc agtggttgga gctaccattg cggacaactt cggcgtggcc
     4201 atgccggagg gaacgatcgg atcctccaga ctggaagaaa ttgagaaata acaggagaat
     4261 aatcaggaga aaaatatgga aaaacaggaa attttaaagc gtcttgatca cactctgctt
     4321 cagcagacag ctgtctggga gcagattaag gttctctgcg acgagggcat ggaatatgga
     4381 acagcgtctg tgtgcattcc gcccagcttc gtaaaaagag cgaaagagta tgtgggagac
     4441 agactggctg tctgcacggt tatcggcttt ccaaacggct atatgactac ggctgcgaag
     4501 gtttttgaga cagaggacgc agtgaaaaac ggagccgatg aaattgatat ggttatcaat
     4561 atcggcatgg taaaggaaaa agattatgac ggcgtcctgg ctgagatccg ggggatcaag
     4621 gaagcctgcc gcggaaagct tttaaaggtt attatcgaga cctgcctgct gactgaggag
     4681 gagaaggtgg aactgtgccg cgtggttaca gaatcaggag ctgagtacat taaaacctcc
     4741 acaggattct ccacaggcgg agctacgttt gaggatgtgg cccttatgag aaagcatgtg
     4801 ggaagcggag tgaaggtaaa ggcggcaggc ggaatcgcca gcgtttcaga cgcagagaag
     4861 tttattgagc tgggcgcaga ccgtctggga accagccgtc tgatcaagct gctggaggca
     4921 gaataacaga aaaaagggac tgacgggaaa gggaggaata ctccctttcc acgttttttc
     4981 ataatccggt tgacagccgg attattttgt tgtataactg tattaagcaa ttaatacaac
     5041 aatacaatga tacagatggc cggatacagc agacggagac ggactgcttt caggaagaaa
     5101 atgaggtgaa aaaatggaat ggaaaattac agacgacagg cctatctgga tgcagctttc
     5161 agaacagctt tctgcccaga tagcggcggg gacttacggg ccgggagaac ggctcccttc
     5221 agtccgggaa tttgcagccc aggcaggggt gaaccctaac accatgcaga gagcgatggc
     5281 tgatttggaa agccaggggc tgattactac aaacagaaca gcaggaaggt gtgtgacgca
     5341 ggatatggaa aggattaaac aggtcagaaa cagccaggcc agggagcagg ccatccgttt
     5401 tttagagcag atgggaagtc tgggatacac gagagaagag attaaacatg tactggaaga
     5461 attgtttgac acgatgaagg aggaggggac agtatgagca gggaaatttt agtttgcaaa
     5521 ggcttgggga aaaaatttgg aaccagatac gctctgaagg atgtggatct taccatagaa
     5581 agcggaaaga ttatcggact tttagggccc aacggttcgg gaaagacgac tcttatgaag
     5641 ctggccaacg gccttttaaa gccggaggag ggatggctgt ccattgacgg aaatgaacct
     5701 ggtgttgaga ccaaggcggt ggtttcttac ctgccggatc agacctactt tgccgactgg
     5761 atgcgggtat cggatctttt gaatatgttt tctgattttt acagagattt cgacagacag
     5821 agagcggccg ccatgctgaa ggatctggat atttccgaga aggccaggat gaagtccctc
     5881 tccaaaggaa acaaggagaa ggttcagctg attttggtga tgagccggaa tgccaggctg
     5941 tatcttttag atgagcccat aggaggcgta gatccggcgg ccagggagta cattctgcag
     6001 acgattctca ccaattattc agaggacgcg tccgtcatta tttccactca cctgattgcg
     6061 gacgtggaaa aggtgctgga tgaggctgtt tttctgaagg agggccgcct ggtccgtcac
     6121 agcagcgtag acgagataag agagacggaa ggaaaatcag ttgaccacct gttcagagag
     6181 attttcgccg tacagggaag cggaaacgga tctggcgatg gggacagata gaaaggaagg
     6241 cagtatatgt ttggaaagct tttaaaatac gaatggaagg ccatgatgaa aaccatgctc
     6301 cccatttacg gggctactat ggttctggcg gcggtgaacg gattcctgtt tcagagtatt
     6361 ctgggaggat ggatggaccg ttcggccctg ttttctacta tgcagacgac ggcgattacg
     6421 ctttatatgc tgattttgat gatcatggga gtgtttacgg cagttatgat tgtccagcgt
     6481 ttttacaagg ggctgctgag acaggagggg tatctcatgt ttgcgcttcc ggtaaagacg
     6541 tggaagctga tcttttccaa ggcctgcgtt tcctttgccg tttctgtcct gtccatgata
     6601 gtgggaatct tgtccatagg actgtttgga ggccttgatt tcttccgggc tctttacgag
     6661 cttcctatcc tgatgtgggc ttttatgcag gaagggtatg aagcgaatcc ggaggctttt
     6721 gcatacatgg tattgtttgc gctggaggta ttggctggac ttgccgtggc ggcgtttgct
     6781 tccatctacg agctgtattt ttccatggcc ctgggacagc tgtccaggaa tcacaaggta
     6841 atctggtcag tgttctggtt tatggcagtg agcacagcga tgaattttgt ggcaatgctt
     6901 ctcgtgggaa acgggatgga tctgatggat tttgcagaga cggcagagga tatgactatg
     6961 agacttcata tggcggggct tggaatgctg gccgttcagg ctgtcagcct ggtgcttctg
     7021 atgtttggaa cagggtatgt gctggaccga aaactgaatc tggaatagat agaagggcag
     7081 ccgggctttt ggcggcgggg aaggaagaga cttccctgcc gattttttat ataattaaaa
     7141 agcatggttt atagaacagg tttcggcaca gatgcggcaa actggtagcc gtttctccgg
     7201 gttctcttta cctcgtacag agccttgtct gccgcctcat agagctgggc aaaggattct
     7261 ccgccctgga cagggacgat tccgatggaa gcgctgacgg ttacagagta ttccgtgctg
     7321 gaaaaagtac ggttcagggc tgaaaccagc ttctctgcac agcgttccag gccacggtga
     7381 tccgccgcgt tctggataaa cagtacaaat tcatccccgc ccagacggcc cgacagatcg
     7441 gtgcttcgaa cgacagattt caggatcaat ccagtttcct gcagaacctg atctcccgcc
     7501 atatgtccca gctggtcgtt cacttcttta aaatggtcca gatccagaag aaacagagcg
     7561 ctgactcccg ggctgttgct gtcaggcaag cgcagaattt cctctgtctt ctggataaag
     7621 gtttctctgt tgtaaaggcc tgtcagcgga tcgatctgat ttttcagatt aatcgcttca
     7681 atcgtccgct cgctcttcat ctgttcgttg taatcctcca gaaatccgat gacgtgctct
     7741 ctgtcaactg taagagcgtg gatcttattg cagtcccatc tgtgattcag ccagatgtcc
     7801 agcacaatcg gttctgccgt tccgccgctc ataaccgttt cgtaaaaggt cttgtaggaa
     7861 tcatagccct cttctcgtat gaggcctgct ttcaggagat aatccggggt aaaatcagag
     7921 attacctggt aatccagtcc cgattcattg ggatgctggt ggtagagaaa aagcaggttc
     7981 tgctccaggt tgatctcaaa aggaatgtcc tgggttttct tcaaaatagt ggagagaagg
     8041 gaatttttca cctgaatctc ctgattctgt atctgaatcg ttttcattac ccggcggata
     8101 aaatggccga taatcagaaa aactgctacg acgcagacag aaaggcctgc cagaagccat
     8161 acaaaaatat gctcaatatt ttctgcataa tccttcagaa agctttccac taccacagaa
     8221 aaaacgtacc agttgttgat gccgagaggc tcgtaagtca catatctgcc ctgattttga
     8281 aaggaaaagt aaaaatatcc ggattcgccg ttgataacgt cctggtggat actttctacc
     8341 gtcacgccgt cggcaaaggt ataccgcttc atttcctccc agatgttcat atcctcggca
     8401 aaggcataga cgtttccaga gtggatgatg tagtttccgt tatcgtccac aatctggaaa
     8461 tagcggtgca tttctttgtc catctcgata ctttcagcaa tcgaagaaat ggacaggtag
     8521 ccccacagag ctcccacgac ctgtccgcca tgatgaaggg ggacggcgat taccatatcg
     8581 tcagaggcag tcagaacatt ggaaatatag ctttgatcgt tcagaatact ctcaaatagc
     8641 cggggatccg ccagctttct gataactcca gtatcatcta tgctggatcc gtccagactg
     8701 gcaactccta ttttttcgaa atgaagcccc tcccgtattt cctgcaggct gccttgtacc
     8761 cccttctgcc cggttccctc gcttgcgtga aatatttctt cgctggcctg cagaatatcg
     8821 acgctgtgct ggatttctgt atggatcagc ttcgtgacat agtgggaggt ccactcaatc
     8881 tgttccatat ctttttccag aacagagctg taaaccttat taaagtaaat gataaacagg
     8941 ctgatcataa taatgatgga aagaataatg gctgttgtaa tgactatcag cggcttgctt
     9001 ccagaacgca tgcctgatat gcgcgacttt tccatatagt aaattctccc tgtacagttt
     9061 tactgtgatt gtcagaatag ggtgacaaaa tacccattaa ttataattat acaataaagg
     9121 gatttatttg aatagtctta agataggaaa ttgtaggttt gtcaaacatt tgttacacgg
     9181 attgtaaata ttcctgaagt acctcattgg gtgatttcca tcccagtgga cgcatgggaa
     9241 agttgtta
//
LOCUS       DBMDUW010000079         7477 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_4286_length_7477_cov_3.897641, whole genome shotgun sequence.
ACCESSION   DBMDUW010000079 DBMDUW010000000
VERSION     DBMDUW010000079.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 7477)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 7477)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7477
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4286_length_7477_cov_3.897641"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..252)
                     /locus_tag="ACZPCR_11185"
     CDS             complement(<1..252)
                     /locus_tag="ACZPCR_11185"
                     /inference="COORDINATES: protein motif:HMM:NF025126.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HIR1231461.1"
                     /translation="MCQLPRLHKCTESKKYVKTVIRHIWEEYMEMAEDIGNKEIYEQR
                     KETSERIFGTVKEQQGFRYTQYIGKFRMNFSSFLGFWLKN"
     gene            complement(670..759)
                     /locus_tag="ACZPCR_11190"
     tRNA            complement(670..759)
                     /locus_tag="ACZPCR_11190"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(722..724),aa:Ser,seq:cga)
     gene            complement(928..2397)
                     /locus_tag="ACZPCR_11195"
     CDS             complement(928..2397)
                     /locus_tag="ACZPCR_11195"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HIR1231462.1"
                     /translation="MIGRKGAGKKHLRENSSSGSSCSLEKKEGKGRSRKQSFSDRRRQ
                     EKRRAGALLSALFLVCMTGVFGLGSFFSNPALLGLQTPEPISAEEEKENLAQAPQRRT
                     RTQEGEPDAIQEGMEEGMEPGMKTEPLPENPAIYLNDTLAGLTDSQLNRLGVFGTPQE
                     EPEIGQVENDLTTANGFETRDDQVVVQGDGVNLRAESQTESRIIVQLKTGDTLQRTGE
                     NGEWSRVVYEGTECYVSNQFVAVKQPEPEPDSTAGVRAAAASEDDGLVRAASEGEIQP
                     IGQGPVVVIDAGHQNKENIRKEPAGPESSRMSQKMEAGAVGSFLGVRECDVTLAIAEK
                     TKQVLTERGYQVIMTRESNDVNMSWAERARLAEKSGAGALIHIHAHSQESTSVTGVLA
                     SCQSSRNPYNGDLASESYALSSCIAGSVSQAAGAKNRGVKQTDTSSEINWSQVPVTSL
                     ETGFLSNQQEELLLSQEEYQSQIAVGIADGLDQFFAGRR"
     gene            complement(2394..3473)
                     /gene="mnmA"
                     /locus_tag="ACZPCR_11200"
     CDS             complement(2394..3473)
                     /gene="mnmA"
                     /locus_tag="ACZPCR_11200"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HIR1231463.1"
                     /translation="MEKRKVVVGMSGGVDSSVAAWLLKKQGYDVIGVTMQIWQDEDRQ
                     TEEENGGCCGLSAVDDARRVASKLEIPYYVMNFKKEFRKHVMDYFVDEYLNARTPNPC
                     IACNRYVKWEALLKRSLDIGADYIATGHYARIEQLPNSRFALRKSATAEKDQTYALYS
                     LTQEQLSHTLMPVGEFTKDEIRAMARELDLQTANKPDSQEICFIPDHDYAKFIAEDMD
                     KELPEGNFVDQNGRILGRHKGLIHYTIGQRKGLNLSMGRPVFVVELRPETNEVVIGDS
                     QDVFSKTLRCSRLNWMAVDGLHGREMRFTAKIRYGHKGALCTVRELGPDLVECEFDEP
                     QRAVTPGQAVVFYDGEYVAGGGTIL"
     gene            complement(3478..3915)
                     /gene="nifU"
                     /locus_tag="ACZPCR_11205"
     CDS             complement(3478..3915)
                     /gene="nifU"
                     /locus_tag="ACZPCR_11205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008391662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HIR1231464.1"
                     /translation="MYSEKVMDHFQNPRNVGEIENASGTGTVGNAKCGDIMRIYLDID
                     ENQIIRDVKFKTFGCGAAVATSSMATELVKGKSIQEAMQVTNKAVMEALDGLPPVKVH
                     CSLLAEEAIHAALWDYAEKNGIQIEGLEKPKSDISEEEEEEEY"
     gene            complement(4027..5211)
                     /gene="nifS"
                     /locus_tag="ACZPCR_11210"
     CDS             complement(4027..5211)
                     /gene="nifS"
                     /locus_tag="ACZPCR_11210"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006775481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HIR1231465.1"
                     /translation="MKQFIYLDNAATTKARPEVVEAMLPYFTEQYGNPSSVYDFSAGP
                     KKAIADARETIAKSLGAKTNEIYFTAGGTESDNWALVATAEAYQAKGNHIITSKIEHH
                     AILHTCQYLESRGFEVTYLDVDENGVVKLEELKKAIRPETILISIMFANNEIGTIQPI
                     KEIGAIAKEHGILFHTDAVQAFGHLPIQVDECHIDMLSASGHKLNGPRGIGFLYIRTG
                     VKSHSFIHGGAQERKRRGGTENTPGIVGLGKACEIAMATMEERTRRERELRDYLIDRV
                     LKEVPYTRLNGHPVDRLSNNANFAFQFIEGESLLIMLDMDGICGSSGSACTSGSLDPS
                     HVLLAIGLPHEIAHGSLRLTLNEEITKEQLDYTVESIKKIVERLRSMSPLYEDFVKHQ
                     GR"
     gene            5363..6910
                     /locus_tag="ACZPCR_11215"
     CDS             5363..6910
                     /locus_tag="ACZPCR_11215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006781992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative polysaccharide biosynthesis protein"
                     /protein_id="HIR1231466.1"
                     /translation="MKKNPLITGTILLTGAGFLSRILGFFYRIFLSRAIGAEGLGVYQ
                     MVFPIHSIAFALCCGAIQTSISRLVARNEQLGRAALRTGLFISLSISAVLTLLIWQAS
                     PWLARFVLLEPACGPLLPVMALSIPFSSIHACICGYYYGMKRTAVPALSQMAEQLVRM
                     GAVFLMVQVLTENGRPVTVSVAVWGMMIGEAASAVYSYLTYAASEMGKLKRQTGRQPE
                     NRQASFFQMAGPLMAMAVPLMGNRLILNCLQSLEAIFVPNRLIAFGLSHSDALSLYGV
                     LTGMALPFIFFPSAVTNSLAVVLLPTVAEAQAQDNSSRIEKTIAAALRYSLYMGIFCI
                     GLFTLLGPDLGMTVFRNQTAGQYIAVLAWLCPFMYISTTMGSILNGLGKTSSVFLHNA
                     VSMLVNLAFVVFGIPRMGMRAYFYGLLLSELLLALLHLRCLHKAVRVSIEPWEMIVKP
                     CLCLAAAAGLLKLCAPALASLKAAGMNEFLCLAGQGAVVSAGYGGLLWQMHRARRRQN
                     RSSRFDS"
     gene            complement(6998..7375)
                     /locus_tag="ACZPCR_11220"
     CDS             complement(6998..7375)
                     /locus_tag="ACZPCR_11220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HIR1231467.1"
                     /translation="MKQVISTEKAPAAIGPYSQAIEVNGMVYTSGQIPVNPATGEIAG
                     TIEGQARQVMENVKNLLAAAGATMDQVVKTTVFIKDMNDFGKINEIYAEYFKDACPAR
                     SCVEVARLPKDVLMEMEAVAAKQ"
BASE COUNT         1529 a         2162 c         1663 g         2123 t
ORIGIN      
        1 attcttcagc caaaatccca gaaaactcga aaagttcatc cggaattttc caatatactg
       61 ggtataacga aatccctgct gctcctttac tgttccaaaa atccgttcgc ttgtttcttt
      121 cctctgttca taaatctctt tgtttccgat atcttctgcc atttccatgt actcttccca
      181 aatatgacgt atcactgtct tcacatattt tttactttcc gtacatttat ggagtcttgg
      241 caattggcac acacttctcc gcggctttgg tattctttat atccatcccc gttcacagta
      301 cgatataata tccaattttc caggcataag taacaatcat aagcctcgtc atatatactc
      361 gtatttacga aaaaatcctt gagcatgggg cttttgtata gaaacaatgg tttaattcca
      421 ttcgtcaaca attcacggga aatcgcctga tttcgctcac tggcatccat tacgagcatc
      481 gcaggaccgt aattctttat cttatcaccc ttttccgtgg ttttcctttt tctatctttt
      541 cctaattttc aacttctttt tcctagtgca gtccccgaat agtcctcaaa aacaaaaaaa
      601 gacacccttt tccgggtgtc tcttcttttc cacaaacaag aaaaaccctt gatttacaag
      661 ggtttcaagc ggagacggtg ggattcgaac ccacgtgccg ggatgaaccg acaaacgcat
      721 ttcgagtgcg ccgcgttacg gcctcttcgc tacgtctcct gatgtggccg cctgttcttc
      781 caggcggcac tttttctatt atactagact tttcttcgtt tgtcacctgg ttttggacaa
      841 ttatttatct atcaaatata tgactcagat atatttctca atatatttta gatatacatt
      901 ttgtccacca ggccgcctgc cgttctctta acgcctgccg gcaaagaact gatccaggcc
      961 gtctgctatt cccactgcaa tctgagactg gtactcctcc tgcgagagca gaagctcctc
     1021 ctgctgattg ctgagaaagc ctgtttccag agatgtgacg ggaacctggc tccaattgat
     1081 ctcgctggaa gtatccgtct gtttcacgcc cctgttcttc gcacctgcag cctggctgac
     1141 gcttcccgct atgcagcttg acagagcata gctttcagaa gccaaatctc cgttgtaggg
     1201 atttctggag gactggcagg acgccaggac gcctgtaaca gaggtgcttt cctggctgtg
     1261 ggcatgaatg tggatcagcg cccctgctcc gctcttttct gccagcctgg ctctctctgc
     1321 ccagctcata ttcacatcgt tgctctccct ggtcatgatt acctggtagc ctctctctgt
     1381 cagaacctgc tttgtctttt ctgcaatggc cagcgtaacg tcgcactcgc ggactcccag
     1441 gaagcttccc actgctcccg cttccatttt ctggctcatt ctggaggact cagggcctgc
     1501 cggctctttc ctgatgttct ctttattctg gtggcctgcg tcaatcacta ccacaggtcc
     1561 ctggccaatt ggctggattt ctccctccga cgcagctctc accagtccgt cgtcctctga
     1621 cgctgcggca gcacgaactc cggccgtgct gtccggctcc ggttccggct gtttcactgc
     1681 cacaaactga tttgatacat agcactcggt tccctcatag acaacgcggc tccactctcc
     1741 gttctcgcct gttctctgca gtgtgtctcc tgtcttcagc tgaacgataa tccggctctc
     1801 tgtctggctt tcagcccgaa ggtttactcc gtctccctga acaaccacct ggtcatccct
     1861 ggtttcaaag ccattggcag tggtcagatc attttccacc tgtccgatct ccggctcctc
     1921 ctgcggcgtt ccgaaaacac ccagtctgtt taactggctg tcggtcagcc ctgcaagcgt
     1981 atcgtttaaa tagatcgccg gattctccgg aagaggctct gttttcattc ccggttccat
     2041 tccttcttcc atgccttcct ggatcgcgtc cggttctcct tcctgcgtcc gtgtccttct
     2101 ctgcggtgcc tgcgccagat tctccttctc ttcctcagcg gatataggct ctggcgtctg
     2161 aagtcccagc agagccggat tgctgaaaaa gcttcccagg ccgaaaactc cggtcataca
     2221 cacgagaaaa agagcggaga gcagagctcc cgcccggcgc ttctcctggc gccggcgatc
     2281 cgaaaaactc tgctttctgc ttctgccttt tccttccttt ttttccagac tgcaggatga
     2341 acctgaggaa ctattctctc tcaggtgttt cttccctgct ccttttctgc caatcacagt
     2401 atcgtacctc ccccggccac atactcgccg tcataaaata caacagcctg gcctggtgtt
     2461 accgccctct ggggctcgtc aaattcacat tccactaaat caggcccaag ctccctgact
     2521 gtgcagaggg ctcccttatg gccgtagcgg atcttagctg taaaacgcat ttcccggccg
     2581 tgcaggccgt ccactgccat ccagttcaga cggctgcagc gaagcgtctt tgaaaatacg
     2641 tcctggctgt ccccgattac cacttcgttg gtctccggcc tcagctccac cacaaacaca
     2701 gggcgtccca tagacaggtt cagccccttt ctctggccga tggtgtagtg aatcagcccc
     2761 ttatgacggc ctaatatacg tccgttctga tccacgaaat ttccctccgg aagctcttta
     2821 tccatatctt cagcaataaa cttcgcatag tcgtggtcag gaataaagca gatttcctgg
     2881 ctgtccggct tattggctgt ctgaagatcc agctccctgg ccatggcgcg gatctcgtcc
     2941 ttggtaaatt ctcccaccgg catcagggta tgggagagct gctcctgagt caggctgtaa
     3001 agagcatagg tctgatcctt ttctgctgtc gcagatttac gcagagcgaa gcggctgttt
     3061 ggaagctgct caatcctggc gtaatggcct gtggcaatgt agtcggctcc aatgtcaaga
     3121 cttctcttta acagcgcctc ccatttcaca taccggttgc aggcaataca gggattggga
     3181 gtccgggcgt tcaggtactc gtctacaaag taatccatga catgttttcg aaattctttt
     3241 ttaaagttca tcacatagta gggaatttca agctttgacg ccactcttct ggcgtcgtcc
     3301 accgcactta agccgcagca gcctccgttc tcctcctctg tctggcgatc ctcatcctgc
     3361 caaatctgca tggtcacgcc aatcacgtca tagccctgtt tttttaaaag ccaggcagcc
     3421 acggaggagt cgactcctcc ggacatgcct actactacct tcctcttttc catggaatta
     3481 atactcttct tcctcttctt cctcgctgat atcagacttg ggcttctcca gtccctcgat
     3541 ctgaattcca tttttctccg catagtccca gagagctgcg tgaatcgcct cctctgctaa
     3601 aagggaacag tgaaccttta ctggcggaag tccgtccagc gcctccataa cggccttatt
     3661 cgtcacctgc atggcctcct ggatagattt tccctttaca agctctgtag ccatactgct
     3721 ggtagccaca gctgctccgc agccaaaggt tttaaacttc acgtctctga taatctgatt
     3781 ctcgtcaatg tccaggtaaa ttctcatgat atcgccgcac ttagcgtttc ctacggtacc
     3841 tgttccgctg gcattctcta tctctcccac gtttctcggg ttctggaaat gatccattac
     3901 tttctctgaa tacatagcaa ttctcctatt ctgctttatc tatattaagt tctgatttat
     3961 gttccgcttt atcctctgcc gcagctgttt ttaaagatct ggaaacgtat cccagaggca
     4021 gactgcctat ctgccctggt gcttaacaaa gtcctcatag agcggggaca tggagcggag
     4081 tctctccaca atcttcttaa tgctctccac cgtgtagtct aactgctcct ttgtaatctc
     4141 ctcgtttaag gtaaggcgaa gagagccgtg ggcaatctcg tgaggcagtc cgatcgctaa
     4201 cagcacgtgg gacggatcaa gagatcccga ggtacatgcc gaaccgctgg atccgcagat
     4261 accgtccatg tcaagcataa ttaacaggga ttcgccctca ataaactgga aggcaaagtt
     4321 agcgttattg gagagacggt ccaccggatg gccgttgagc ctggtgtagg gaacctcctt
     4381 aaggacacgg tcaatgagat aatctctcag ctcccgctct cttctggtgc gctcctccat
     4441 ggtagccatg gcaatctcgc acgccttgcc aagtcccacg atgcccggag tgttctccgt
     4501 gccgccgcgg cgctttctct cctgggctcc tccatggata aaggaatgcg atttcacgcc
     4561 tgttctgata tagaggaagc cgattcccct ggggccgttc agcttgtggc cgctggcgct
     4621 gagcatgtca atgtggcact cgtccacctg aatcggcaga tggccaaagg cctgaaccgc
     4681 gtctgtgtgg aacaggattc catgctcctt cgcaatggcg ccgatctcct tgatgggctg
     4741 aatggttcca atctcattat tcgcaaacat gatggaaatt aaaatggtct ccggacggat
     4801 ggccttctta agctcctcta attttacaac gccgttctca tccacatcca ggtatgttac
     4861 ctcaaaccct ctgctctcca gatactggca ggtatgaaga atcgcgtgat gctctatttt
     4921 cgatgtaata atgtggtttc cctttgcctg gtaggcctct gccgtcgcta ctaaagccca
     4981 gttgtcagac tcagttcctc ctgctgtaaa gtaaatctca ttggtcttgg cgcctaaaga
     5041 cttcgcaatg gtctctctgg cgtctgcaat ggccttcttg ggacctgctg agaaatcata
     5101 tacagaagaa gggtttccat actgctctgt aaaatatgga agcatagcct ccactacctc
     5161 tgggcgcgcc ttggtggtcg ccgcattatc aagataaata aactgtttca ttttaaatcc
     5221 gcctttcgtt ttattttgta ggaataaagg taaaagcttc atctacgttt actattatat
     5281 aggaatttct gggaaacaca agtagtaata attcttattt ataaaaatat aataatatta
     5341 attccccgta ccgggtgttt ttatgaaaaa gaatcccctg attacaggaa ctattcttct
     5401 gacaggagcc ggatttctaa gccgcatcct gggatttttt taccgcattt ttctgtcccg
     5461 ggccattggg gcggagggac tgggcgtcta ccagatggta tttcccattc attctatcgc
     5521 ctttgccctc tgctgcggag ccatccagac ttccatctcc cgcctggtag ccagaaatga
     5581 gcagctggga agggccgccc tgcggacagg gcttttcatt tccctgtcca tctccgcagt
     5641 cctcactctt ctcatctggc aggcttcccc ctggctggcc cgcttcgtcc tcttagagcc
     5701 tgcctgcggc cctctgctcc ctgtcatggc tttgtccatc ccgttttctt ccattcacgc
     5761 ctgcatctgc ggctactatt atggtatgaa gcggaccgcc gttccggcac tgtcccagat
     5821 ggcagaacag cttgtccgca tgggagcggt ctttctcatg gttcaggtgc tgactgaaaa
     5881 cggccgccct gtcactgtct ccgtggctgt ctggggcatg atgatcggcg aagcggcttc
     5941 cgctgtctac agctatctga cctacgcggc ctcagagatg ggaaagctga agaggcagac
     6001 gggcagacag ccggaaaacc ggcaggcctc tttttttcag atggcggggc ctctcatggc
     6061 tatggccgtc cccctcatgg gaaaccggct gattttaaac tgcctgcaga gtctggaagc
     6121 catcttcgtg cctaaccggc tgattgcttt cggactgagc cattctgacg ccctgagcct
     6181 gtacggagtt ctgaccggca tggccctgcc ctttattttc tttccttccg ccgtcaccaa
     6241 ttccctggcc gtagtcctgc ttcccactgt ggcagaggcc caggctcagg acaacagcag
     6301 ccgcatcgaa aagaccatcg ccgctgcgct gcgctacagc ctctatatgg gaattttctg
     6361 catcggcctg ttcacgcttc tgggccctga tctgggaatg actgttttcc gcaatcagac
     6421 agccggacaa tatattgccg ttctggcatg gctctgccct tttatgtaca tttccaccac
     6481 tatgggaagc attttaaacg gcctcggaaa gacttcctcc gtttttctcc acaacgcagt
     6541 ctccatgctg gtcaatctgg ccttcgtggt attcggaatt ccccgcatgg gaatgagggc
     6601 ctatttttac ggacttctgc tcagcgagct gctgctggct cttctgcacc tgcgctgcct
     6661 gcataaagcg gtccgcgtct ccatagaacc atgggaaatg attgtaaagc cctgtctgtg
     6721 cctggccgcc gccgcaggac ttttaaagct ctgtgctccc gccctggcgt ctctcaaagc
     6781 ggcaggcatg aacgaattcc tgtgtctggc cggacagggc gccgtcgtca gcgccggata
     6841 tggcggcctg ctgtggcaga tgcacagagc acggcgcagg caaaaccgca gcagccgctt
     6901 tgacagctga aaggcagaaa acagacaaag cctccggaga gaatacgctc cgagggcttt
     6961 tcttggctgc agtcaattct gcagtccgcc ttatttttta ctgcttcgct gccaccgctt
     7021 ccatttccat cagtacgtcc ttaggaagtc tcgctacctc cacacaggat ctggccgggc
     7081 aggcgtcctt aaaatattcg gcgtaaatct cgttgatttt tccgaaatca ttcatatcct
     7141 taataaatac tgtggttttt accacctggt ccatcgtggc tcccgctgcg gccagaagat
     7201 tcttcacgtt ctccattacc tgtctggcct ggccttcgat tgtccctgca atctctcctg
     7261 tagccgggtt gacaggaatc tggccggaag tgtaaaccat tccgtttacc tcgatagcct
     7321 gggagtaggg tccgatagct gccggcgctt tctctgtgct gattacctgt ttcatagtta
     7381 tattcattcc tttcgcttcg ctcagacaca aaacgttatg aaaatgtttt cctgagctta
     7441 ttttttcttt ataattcttc ttatagggaa ctcggta
//
LOCUS       DBMDUW010000080         7375 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_4336_length_7375_cov_2.807396, whole genome shotgun sequence.
ACCESSION   DBMDUW010000080 DBMDUW010000000
VERSION     DBMDUW010000080.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 7375)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 7375)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7375
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4336_length_7375_cov_2.807396"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            141..386
                     /locus_tag="ACZPCR_11225"
     CDS             141..386
                     /locus_tag="ACZPCR_11225"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231468.1"
                     /translation="MFLRLLDEIPVKSIGIAGFDGYEYLGKGGNYAKKEMETDNVSQE
                     AVELNKEIAEMLVDYKKTRKRNHPIIFITPSRFSGIF"
     gene            816..1517
                     /gene="pyrH"
                     /locus_tag="ACZPCR_11230"
     CDS             816..1517
                     /gene="pyrH"
                     /locus_tag="ACZPCR_11230"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HIR1231469.1"
                     /translation="MEMKRVLLKLSGEALAGEKKTGFDEETVKEVARQVKLAVDAGIE
                     VGVVIGGGNFWRGRQSNAIDRTKADQIGMLATVMNCIYVSEIFRSTGMETEILTPFAV
                     GAMTKLFSKDRANKYFKQGKVVFFAGGTGHPYFSTDTGVALRAIEMEADCILLAKAID
                     GVYDSDPKLNPEAKKYDTISIQEVIDKQLAVVDLTASIMCMENHVPMAVFSLNEKDGI
                     ANAMQGKINGTVVTA"
     gene            1532..2086
                     /gene="frr"
                     /locus_tag="ACZPCR_11235"
     CDS             1532..2086
                     /gene="frr"
                     /locus_tag="ACZPCR_11235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HIR1231470.1"
                     /translation="MQEKMKVFEDKMEKSYDALLNEFSSIRAGRANPHVLDKLKVDYY
                     GAPTPLQQVANISVPEPRMIQIQPWEKSLVKAIEKAILTSDLGINPNNDGSVIRLIFP
                     ELTEERRKELAKDVKKKGEGAKVAVRNIRRDANDTFKKMEKANEISEDDLSDAEEKIQ
                     KLTDKMIDKIDKAVDTKTKEIMTV"
     gene            2142..2864
                     /locus_tag="ACZPCR_11240"
     CDS             2142..2864
                     /locus_tag="ACZPCR_11240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007711318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HIR1231471.1"
                     /translation="METDISKMAIPAHVALILDGNGRWAKKRGLPRTAGHKQGCVTVE
                     KTVEDAARLGIKYLTVYGFSTENWKRSVEEVSALMQLFRYYLKRLLKIAKANNVRVKM
                     IGDRTRFDSDIIEGIDRLEQETAANTGMTFVIAVNYGGRDEIRRAVSRMMKDAQAGVL
                     NPDQVTEETVASYLDTAGIPDPDLLIRTSGEIRLSNYLLWQLAYSEIYITDCLWPDFN
                     RDELVKAIAQYNTRERRFGGAK"
     gene            2884..3684
                     /locus_tag="ACZPCR_11245"
     CDS             2884..3684
                     /locus_tag="ACZPCR_11245"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HIR1231472.1"
                     /translation="MFTTRLISGIVLVILAILIVGTGGTLLFAVTAALSLIGMFELYR
                     VVQIEKKAPGFAGYAAGIFYYILLWFHKEEYIVLMAIMALMVLMAIYVVTFPHYKTEQ
                     VTVAFFGIFYLAVMLSYLYQVRAMADGRYLVWLIVLSSWGCDTFAYCAGMLFGKHKLT
                     PVLSPKKTVEGAVGGVLGAALLGLIFGAVFGGRMEEIVSPAVVCAIACAIAAVISQIG
                     DLAASAIKRNHDVKDYGHLIPGHGGVLDRFDSMIFTAPAIFFALTLLG"
     gene            3749..4894
                     /gene="dxr"
                     /locus_tag="ACZPCR_11250"
     CDS             3749..4894
                     /gene="dxr"
                     /locus_tag="ACZPCR_11250"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004844599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0030604 - 1-deoxy-D-xylulose-5-phosphate
                     reductoisomerase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HIR1231473.1"
                     /translation="MKKITILGSTGSIGTQTLEVARTNQDIEVTALAAGRNITLLEQQ
                     IREFRPKLAAVWDEEDAKTLRTAVKDLDVRVLSGMDGLIEVCTEPSAEIVVTAIVGMI
                     GIRPTIAAMEAGKDIALANKETLVTAGHIIMPLAERTGVKILPVDSEHSAIFQCLNGE
                     THNKIHKILLTASGGPFRGRTRQQMMDIQVEDALKHPNWTMGRKITIDSSTMVNKGLE
                     VMEAKWLFGVSMDQVQVVVQPQSVIHSMVEFEDGAVIAQLGTPDMKLPIQYALYYPER
                     RFLPGERLDFTKHGQITFEAPDYENFRGLALAREAGKRGGSLPTVFNAANELAVAAFL
                     DRKIGYLTITDMIEAAMNQHQVIENPSVEEILDTEQETCEFLRRHFL"
     gene            4925..6163
                     /gene="rseP"
                     /locus_tag="ACZPCR_11255"
     CDS             4925..6163
                     /gene="rseP"
                     /locus_tag="ACZPCR_11255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HIR1231474.1"
                     /translation="MLSLLAAILVFGLIILFHEFGHFLFAKLGGICVLEFSLGMGPRL
                     ISFKRGDTRYSLKLLPFGGSCMMLGEDEDPEDFEEKAEKDIRRKSGLLLDEDEEEEEE
                     AQNTLSSETGQDTCALEEEYGIPEEQGNEPPVRYAPDGTPVSGLAFHEAPILARFLTI
                     AAGPVFNFILALACGIAVVAYAGCQPPEIVQVQAGSPAAEAGLQTGDVITRMNGKRIH
                     LYQEVAMYNTFHPGETVNLEYRRGDETHKTAVTPAYSEETGGYLMGISGGIPRAPKSL
                     FETIQYSAYELRYMVDLTFQSLKMLVTGQVSRKDVAGPVGIVVMIDQTVEASSSYGIL
                     TVFINLANMCLILSANLGIMNLLPIPALDGGRLVFILIEAVRGKPVDPEKEGMIHMAG
                     MAVLMTLMVLILFNDIANLF"
     gene            6179..7255
                     /gene="ispG"
                     /locus_tag="ACZPCR_11260"
                     /gene_synonym="gcpE"
     CDS             6179..7255
                     /gene="ispG"
                     /locus_tag="ACZPCR_11260"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008398396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HIR1231475.1"
                     /translation="MTYRASTKPVQIGSRVIGGGNPVLIQSMCNTKTEDSASTIAQIL
                     ELERAGCDIIRVAVPTMEAAESLKTIKKAIHIPLVADIHFDYRLAIAAIECGTDKIRI
                     NPGNIGSEERVQAVVDKAKEYGVPIRVGVNSGSLEKHLIEKYGGVTAEGIVESALDKA
                     ALIERMGYDNLVLSIKSSDVMMCVKAHELIAKKTPYPLHVGITEAGTILSGNIKSAIG
                     LGLILNQGIGDTIRVSLTGNPVEEVKSAKLILKTLGLRTGGVEVVSCPTCGRTQIDLI
                     GLANQVETMVQEYPLDIKVAVMGCVVNGPGEAREADLGIAGGIGEGLLIKKGEVIRKV
                     PEAELLNALKAELDQMLKNAGEKE"
     gene            7252..>7375
                     /locus_tag="ACZPCR_11265"
     CDS             7252..>7375
                     /locus_tag="ACZPCR_11265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III N-terminal
                     domain-containing protein"
                     /protein_id="HIR1231476.1"
                     /translation="MKPFLDVFPDLHITDNLRELLELVEVERVTASRDRSSIRVY"
BASE COUNT         1908 a         1593 c         2162 g         1712 t
ORIGIN      
        1 tttacattgc cgcaggtaga tgaggcggaa gccggaaaat gtgcggataa agatgccgcc
       61 acgacttgct ttgtggatgg caatacgctt ttgatagatt gataaaatgc ggctggattc
      121 atgtagacaa ttcgaccctg atgtttctga ggctgttaga tgaaatacct gttaaatcaa
      181 tcggtatcgc aggatttgac ggatacgagt atttgggaaa gggaggaaac tatgccaaaa
      241 aagaaatgga gacagacaat gtgtcccagg aagcagtgga actaaataaa gaaatagcag
      301 aaatgctggt ggattataaa aaaactcgaa aacggaatca cccaattatt tttataactc
      361 cttccagatt cagcggtata ttttgaagag aatttttttc ttgatacttt cgtgaagcca
      421 tgttgaaact cacaatattt ttcagtccct tgcaggctac ggcacaaaac atggaagaat
      481 tcccaattcc caatttcgac gcgagatgca aagggatatc tgcaggacta ttggaaacag
      541 caccaacgaa caaaaggcag agatttttgt ggcctccagc ggaacggaat ctctgtctct
      601 gttccaaaag atacacagcc gaactgctac aattttttga agaagaataa aaatcccctc
      661 gcgcaaaccc gcattctgtg gtacaatagc cctaagcggg caggaggaga ggatctgcac
      721 gccgggcatt ctgccggata tttcatgtat ccgccagggt cccggctgtt ttttcggatt
      781 ccgccccatt acaagaaaac agggagatca gatttatgga aatgaaacgc gtattgctga
      841 aattaagcgg cgaagccctg gcaggagaga agaagacagg cttcgacgag gagactgtca
      901 aggaagttgc cagacaggtg aagctggctg tggacgcagg cattgaggtc ggtgtggtga
      961 ttggaggcgg aaacttctgg agaggccgtc agagcaacgc tatcgaccgt acgaaggcag
     1021 atcagattgg catgctggct acagtgatga actgcatcta tgtttctgag attttcagaa
     1081 gcacaggcat ggagactgag attctgacgc cgtttgccgt aggcgctatg accaagctct
     1141 tttccaagga cagagccaat aaatatttta agcagggcaa ggtagtattt ttcgcaggcg
     1201 gtacgggaca cccgtacttc tctacagata caggcgtcgc tttgagagct attgagatgg
     1261 aggctgactg cattctgtta gccaaagcca ttgacggcgt ttacgacagc gatccgaagc
     1321 tgaatccgga ggcgaagaag tacgacacca tttccattca ggaagtgatc gacaagcagc
     1381 tggctgtggt ggatctgacg gcttccatca tgtgtatgga gaatcatgtt cctatggcag
     1441 tattcagctt aaatgagaag gacggcattg ccaacgcgat gcaggggaaa ataaacggca
     1501 cagtagtgac cgcataacag gaggattttt tatgcaggag aaaatgaaag tatttgaaga
     1561 taagatggag aaatcctacg acgcgttatt aaacgagttc agctccatcc gtgcaggacg
     1621 cgcgaatccg catgtattag ataagctgaa ggtagattac tatggagcac cgactccgct
     1681 tcagcaggtt gccaacatct ctgttcctga gccgagaatg attcagatcc agccgtggga
     1741 gaagagcctt gtgaaggcga ttgagaaagc gattctcacc tctgacctgg gaatcaaccc
     1801 gaacaacgac ggttctgtaa tccgcctgat tttcccggag cttactgagg agcgcagaaa
     1861 agagctggct aaggacgtga agaagaaggg cgagggcgct aaggtagctg tgagaaatat
     1921 ccgccgcgac gccaacgata cctttaagaa gatggagaag gccaacgaga tttctgagga
     1981 cgatttatct gatgcagagg agaaaatcca gaagctgact gacaagatga tcgacaagat
     2041 tgacaaggct gtggatacca agacaaaaga gattatgaca gtataaaaaa cataccgggg
     2101 caggtactcc tgccccttgt ttttcgtggt gggaggatat gatggaaaca gatatttcta
     2161 agatggcaat tccggcccat gtggctctta ttctcgatgg aaacggcaga tgggctaaaa
     2221 agaggggact tcccagaacg gcaggccaca agcagggctg cgtcacagta gaaaaaacgg
     2281 tggaggatgc cgccagactg ggaatcaaat atttgacagt ttacggattt tccactgaaa
     2341 actggaagcg gtctgtggaa gaggtcagcg ctctcatgca gctgttccgc tactacttaa
     2401 agcgtctgtt gaagattgcc aaggccaaca acgtgcgggt taaaatgatt ggagacagaa
     2461 cgcgctttga cagcgatatt attgagggaa ttgaccgcct ggagcaggaa actgccgcca
     2521 acactggcat gaccttcgtc attgccgtca attacggagg ccgcgatgag atccgccggg
     2581 cagtcagccg catgatgaag gatgctcagg ccggcgttct caatccagat caggtgacgg
     2641 aggagacggt ggcttcctac ctggacacgg cggggattcc ggatccggat ctgttaatcc
     2701 gcaccagcgg tgagatccgt ctgtccaact atctgctctg gcagctggcc tacagcgaga
     2761 tctacattac agactgcctg tggcctgatt ttaacaggga tgagctggta aaggccattg
     2821 cccagtataa tacgagagag cggcggttcg gcggcgccaa ataacgaaag aggggataat
     2881 gtcatgttta caaccagact gatcagcgga attgtgcttg taattctggc aattttaatc
     2941 gtcggaaccg gcggaaccct tttatttgcc gtcacggcgg ctctgtctct gattggaatg
     3001 ttcgagctgt accgtgtggt gcagatagaa aagaaggcgc cgggattcgc cggatacgcc
     3061 gccgggattt tttattacat cctgctgtgg tttcacaaag aagagtatat tgtgctgatg
     3121 gctatcatgg cgcttatggt attgatggct atctatgtgg ttacatttcc acactataag
     3181 accgagcagg tgacagtggc gtttttcggt attttttatc tggctgtgat gctgtcctat
     3241 ttatatcagg tccgcgcaat ggccgacggc aggtatctgg tatggctgat tgttttaagc
     3301 tcctggggct gcgacacttt cgcctactgt gccggaatgc tgtttggaaa gcacaagctg
     3361 acgcctgtcc tgagtccgaa gaagacggtg gagggagccg taggaggtgt tttgggcgcg
     3421 gctctgctgg gcctgatttt cggcgctgta ttcggcggca gaatggaaga gatcgtgagt
     3481 cctgccgttg tctgcgccat tgcctgtgcc attgcggcgg tgatctcaca gattggggat
     3541 ctggcggctt ctgccattaa gagaaaccat gatgtgaagg attacggcca tctgattccg
     3601 ggccacggcg gagtgctgga tcgctttgac agcatgattt ttaccgcgcc ggctattttc
     3661 tttgccctga cgctgctggg ctaaagatgg aagcggcttt ggctgtgcgt tttctgatat
     3721 gctgacgcga aagagaacgg aggaagatat gaaaaaaatt acaattctgg gttccactgg
     3781 ttccatcggc acacaaaccc tggaagtggc gcggacgaat caggatatag aggtaacggc
     3841 tctggcagct ggaaggaata ttactctgtt agagcagcag attcgggagt tccgcccgaa
     3901 gcttgcggct gtatgggatg aggaggacgc gaaaacactg cggactgcgg taaaggatct
     3961 ggacgtccgg gtactgtctg gaatggatgg tctgattgag gtctgcacag agccgtctgc
     4021 tgagatcgtg gtgacggcga ttgtgggaat gatcggcatc cgtccgacca tcgccgctat
     4081 ggaggctgga aaggacattg ctctggccaa taaggagacg cttgtgacgg caggccatat
     4141 tattatgccg ttagctgagc ggacgggagt gaagatcctg ccggtagaca gcgagcacag
     4201 cgcgattttc cagtgcttaa acggagaaac tcataataaa atacataaga ttctgctgac
     4261 ggcttccggc gggcccttcc gaggaaggac gagacagcag atgatggaca ttcaggtgga
     4321 ggatgcgttg aagcatccca actggacgat gggcagaaag atcaccattg acagctccac
     4381 tatggtcaac aaaggcctgg aggtgatgga ggcgaaatgg ctgttcggcg tgtctatgga
     4441 tcaggttcag gtggtggttc agccgcagag cgtgattcac tctatggtgg agtttgagga
     4501 tggggctgtg atagcccagc tgggaacgcc tgatatgaag cttcccatcc agtacgccct
     4561 ctactatcct gagaggcggt ttctgccggg agagcggtta gatttcacaa aacatgggca
     4621 gattaccttt gaggcgcctg attatgagaa tttccgcggc ctggctctgg cgagagaggc
     4681 gggaaaacgt ggcggttccc ttccaactgt gttcaatgca gccaacgaac tggcggtagc
     4741 ggcgttttta gaccggaaaa tcggctatct gacgattaca gatatgattg aggccgctat
     4801 gaatcagcac caggtgattg agaatccttc tgtagaggaa attttagaca cagagcagga
     4861 aacctgcgaa tttttaagac gtcatttttt ataaaccata aaacaagaga gggcaggtgg
     4921 tagattgtta agtttgcttg cggcgattct ggtattcgga ctgattattt tattccatga
     4981 attcggccat tttctgtttg caaagctggg gggaatctgc gttctggagt tttcccttgg
     5041 aatggggcca aggcttatca gctttaagag aggggatacc agatattcgc tgaagcttct
     5101 gccattcggc ggttcctgca tgatgctggg agaggacgaa gatccggagg attttgagga
     5161 gaaggcagaa aaggatatcc gcagaaagag cgggctgctt ttggatgagg atgaggaaga
     5221 ggaagaggag gcacagaata cgctctcttc tgagacaggg caggatacat gcgctttaga
     5281 agaggaatat ggcataccgg aagagcaggg aaatgagccg cctgtccggt atgcgccgga
     5341 cggcacgccg gtgagcgggc tggcgttcca cgaagcgcct attctggccc gctttctcac
     5401 cattgcggcc ggccctgtat ttaactttat cctggctctc gcctgcggaa tcgccgtggt
     5461 agcctacgcc gggtgccagc ctcctgaaat cgtgcaggtg caggctggat cgcctgcagc
     5521 tgaggcaggt cttcagacgg gggacgttat taccagaatg aatggaaaac ggattcatct
     5581 ctaccaggag gtggccatgt ataatacctt tcatcccggt gagactgtga acctggaata
     5641 caggagaggg gacgaaactc acaaaacggc agtgactccg gcttactcgg aggagacagg
     5701 cggctatctg atgggcattt ccggcgggat tcccagagcg ccgaagtctc tgtttgagac
     5761 gattcagtac agcgcctatg aactgcgata tatggtggat ctgaccttcc agagcctgaa
     5821 aatgctcgtt accggccagg tgtccagaaa ggacgtggca ggtccggtgg gcattgtggt
     5881 catgattgat cagacggtag aggcaagcag cagctatgga attctgacgg tgttcataaa
     5941 tctggccaat atgtgcctga ttttaagcgc caacctgggt attatgaatc tgcttcccat
     6001 tcctgcactg gacggaggac gcctggtctt tatcctgatt gaggctgtcc gcggaaaacc
     6061 ggtggatccg gaaaaggaag gcatgatcca catggcaggc atggcggttc tcatgacgct
     6121 gatggttttg attttgttta acgatattgc aaatttgttc tgatcggagg aatctattat
     6181 gacatacaga gcttcaacga aaccagttca aatcggcagc cgcgttatcg gcggcggcaa
     6241 tccggttttg attcagtcta tgtgcaatac aaagactgag gacagcgcgt ccaccattgc
     6301 ccagattctg gagctggagc gggcaggctg cgatattatc cgggtggccg ttccgactat
     6361 ggaggcggct gaaagcctga aaaccattaa aaaggccatt cacatcccgc tggtggctga
     6421 tatccatttc gactaccgtc tggctatcgc ggcgattgag tgcggcaccg ataaaatcag
     6481 gattaatcct ggaaatatcg gttctgagga gagagtgcag gcggttgtgg acaaggcgaa
     6541 ggagtacggc gttcccatcc gggtaggcgt gaacagcggc tctctggaga agcatctgat
     6601 cgagaagtac ggcggtgtga cggcggaggg cattgtggag agcgctctgg acaaggccgc
     6661 cctgatcgag cgtatgggat acgacaatct ggtgctcagc attaagtctt ccgatgtgat
     6721 gatgtgcgta aaagctcatg agctaatcgc caaaaagact ccttacccgc ttcacgtagg
     6781 gatcacggaa gccggaacga ttctctccgg aaatatcaag tctgccatcg gcctgggcct
     6841 gattttaaac cagggcattg gagataccat ccgcgtctcc ctgacaggaa atccggtgga
     6901 ggaggtaaaa tctgccaaac tgattttaaa aacactggga cttcgcaccg gaggagtgga
     6961 ggtggtgtcc tgccctacct gcggacggac gcagatcgat ctcatcggtc tggccaacca
     7021 ggtggaaacc atggtgcagg aatatccgct ggatattaaa gtggctgtga tgggctgcgt
     7081 tgtcaacggc cctggagaag ccagagaggc ggatctgggc attgccggag gaatcggaga
     7141 aggacttctg atcaagaagg gagaggtgat ccgcaaggtt ccggaggcag agctgttaaa
     7201 cgcgctgaag gcagagcttg atcaaatgct taaaaacgca ggtgagaagg aatgaagcct
     7261 tttttagacg tatttcctga tttacatatt acagacaatc tgagagagct tttagaactg
     7321 gtagaggtgg aacgtgtcac cgcctccagg gacagaagct ctattcgcgt ttata
//
LOCUS       DBMDUW010000081         7361 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_4343_length_7361_cov_3.944766, whole genome shotgun sequence.
ACCESSION   DBMDUW010000081 DBMDUW010000000
VERSION     DBMDUW010000081.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 7361)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 7361)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7361
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4343_length_7361_cov_3.944766"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(184..1848)
                     /locus_tag="ACZPCR_11270"
     CDS             complement(184..1848)
                     /locus_tag="ACZPCR_11270"
                     /inference="COORDINATES: protein motif:HMM:TIGR04090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BsaA family SipW-dependent biofilm matrix
                     protein"
                     /protein_id="HIR1231477.1"
                     /translation="MRKGKHAVLGLAALISAAAIGGTWASWTQELKAGNEFMTGSYNT
                     SLDETFESPKNWKPGEKTEKAVQITNKGAVDAMAKVVISQSWESFPLTFQAQNGETEY
                     AAVPEFNKNNVVLLASGDADGKTEENRWGLQAVTQYSQAEGKWLLLNEIPEGEKGIFT
                     LYYMGIVKAGTSSPQFLDGVTMNPRITSGVVDKEYEPEYDSEGSPTGGIIQIATSSSS
                     NGTGYENGTYTMTIDATTVQATQGAAEEIFSAGAEDGDEAQTLDYLVKNIADDGVFEA
                     AEAKTLKFAETDGTMTYIPYRDGDGQAEEGNWFMSFTNMVPGGIYRDRLNIENDSDKT
                     WKLYMKALPREQSALQDELLEKISMKVWYTNADGEEKLLYTGNATGSTLLTQGDTAGG
                     TEGERAVYLGGYKGGQTGSIQVELQLDPTLILTEDPSITPELGESNLVNKYAGALSKI
                     DWQFMVTEVKDDGGNGGGNGGGGHSGGSGGGGGSTVTIGDNEVPLAPEAPLTDETIIE
                     DGPVPLAVLPKTGDETPIIPAVVTLLGSGVILLWMGASLRIKKEEQ"
     gene            complement(1945..2757)
                     /locus_tag="ACZPCR_11275"
     CDS             complement(1945..2757)
                     /locus_tag="ACZPCR_11275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BsaA family SipW-dependent biofilm matrix
                     protein"
                     /protein_id="HIR1231478.1"
                     /translation="MKKRAALGLAGLAAVAAIGGTWAYWNQNLSVDNEFKAGNFDSDI
                     VEEFKPEEDWLPGETVEKVVSVKNSGNVDMAVMTKITQKWDGERMVFEDAEGNEVYAA
                     EVHWGENVAVYEVSEAWPKREELGITKSVGSFDEADNMWVLTGVQEQEDDSLDLYFVY
                     SDIVEEEGETPALLTSVTMSPFIQSDATDKVYEADENGELKVVDAVSSGFHYEDAQYT
                     MTINAKTVQATFDAVKEVFGSALEIAENDKDWVIDDFLRANSIDKPAALEAE"
     gene            complement(2788..3288)
                     /locus_tag="ACZPCR_11280"
     CDS             complement(2788..3288)
                     /locus_tag="ACZPCR_11280"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009249218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HIR1231479.1"
                     /translation="MRLIKGFVNILTWIVYACIACYLLIAAPMLAGYHPVVVLSGSME
                     PTYHVGSVIYYKEADFADINVGDAITFQAGEDGMVTHRVVEKSELSQNFVTKGDANET
                     EDPNPVDYDEVIGKVWKVSIPYAGYFVNYSKNMGVIIVMAAIIVLGIALDMFFPDKKK
                     EEKTEA"
     gene            complement(3332..4201)
                     /locus_tag="ACZPCR_11285"
     CDS             complement(3332..4201)
                     /locus_tag="ACZPCR_11285"
                     /inference="COORDINATES: protein motif:HMM:TIGR04090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BsaA family SipW-dependent biofilm matrix
                     protein"
                     /protein_id="HIR1231480.1"
                     /translation="MNKKLTAIGGLAALAVVGGTWAFFTQDTTIHNKLTTDGMYGLNT
                     TEKFNPGSEWAPGTEVEKKITVKNTGTGAVLVRVKMDENWAYKAAPEQLFGEWASEKD
                     PLAFLEVSERLTNEDGNPLNDFSTVVHKNLDEANIQLDAVEKQDKWYLAEDGYWYFCD
                     KLEGGEATVNLLNSIKLDEKTDMGLIANKYYYIAVEKGADEPDFNADTWNEMKATTEE
                     EAQKELAEIAEGQTDKDFYMTLETKTDENAKGYSDAGYTLNITTEAVQATPDAVEAEW
                     TTAPAELMENILK"
     gene            complement(4245..5156)
                     /locus_tag="ACZPCR_11290"
     CDS             complement(4245..5156)
                     /locus_tag="ACZPCR_11290"
                     /inference="COORDINATES: protein motif:HMM:TIGR04090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BsaA family SipW-dependent biofilm matrix
                     protein"
                     /protein_id="HIR1231481.1"
                     /translation="MKKKHIAALAGLAAVFAVGGSLAYFNQNLEAVNALSVGKFDTTV
                     HEDFKPITDWEPGAEVKKEVRVVNDGNVPAVARVWFVETWTAADGRENSVTNRKTDEN
                     NELLPGESSEDEGNDLTDIYQEDSSDGEIAGDQTVVEKTFNLGKGWEYNQKDGCYYYT
                     SILEGETETPPLLEKIRLTENADMGRMVEKKFYATTEEQPDENSSDWIQFSPDAGGQE
                     VSEADLPDDIREEVKYFRSTIGLETDEDGNPMDSGYAKAEYTLSVIAQTVQATEDAVE
                     AEFGPMAVQAAKEGKWAWNFLGTLSAE"
     gene            complement(5214..5849)
                     /locus_tag="ACZPCR_11295"
     CDS             complement(5214..5849)
                     /locus_tag="ACZPCR_11295"
                     /inference="COORDINATES: protein motif:HMM:TIGR04088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SipW-dependent-type signal peptide-containing
                     protein"
                     /protein_id="HIR1231482.1"
                     /translation="MKLYKRLGIALIGGICAVSVSTTWAVYTDTNTIKNQLSTKHTAV
                     MLKEDFVQFSSFLPGETVTKKPYFENTGDRDMLLRIPKDLAETWRKTEENAEDQLDNE
                     KVIKNWSQYWVNEESSEWFAGEEYYYYNKILTKQGTENSKTNPIMDSLTLSTDVSNDG
                     HEADYSNAEYEITIEAEAVPADKTSAALWAEDLKDADLSVCEWNELLNTTE"
     gene            complement(5853..6551)
                     /locus_tag="ACZPCR_11300"
     CDS             complement(5853..6551)
                     /locus_tag="ACZPCR_11300"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231483.1"
                     /translation="MLKSGKKANAVKLSGIALLTVAVAGIGGTGAVVQHKLAVKNTLK
                     TPTVEVSIDDIVGETEGSKKQKVVSFENQGTADVFIRVAYAEQWEKENELLSSQNSDG
                     HDVAKKFKDTQLENSMENMFSEDEWTLGNDGWYYYRYVLEAANGSATDQTKPLLTAVD
                     FSNVSSQESEYSGAEYELHFQVEAVQSSDDYNLNIKAVDTVFGSGVRLENTQPANWET
                     NKYTSQLEWVEGGN"
     gene            complement(6544..>7361)
                     /locus_tag="ACZPCR_11305"
     CDS             complement(6544..>7361)
                     /locus_tag="ACZPCR_11305"
                     /inference="COORDINATES: protein motif:HMM:NF048838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF7604 domain-containing protein"
                     /protein_id="HIR1231484.1"
                     /translation="EVLLCRPGKEAFEEGVTYQVKVRIKPTQAAMDYYAQNGAYPNTP
                     DAGTGTHADKNELGFYSNTEATLSFSYNGVTYAGDNAFEYPHPVIQILPEGRFVVQKL
                     VEIDDNETPLAGSPDQEFIIQIQEQTADGTNGFKSSVALKDGEMTGTVITEGEKTFNV
                     HEIVPMEYEQSSIVVYENDGNGNPKPETAGVVAEDGNFKVLPGQDLIVRVTNTPVHKD
                     FFHDAFSVTNKTKGDTSTPFTNDLAEQAAKTASKLGLTKKKTELEQEEGDLIA"
BASE COUNT         1638 a         2013 c         1385 g         2325 t
ORIGIN      
        1 ctattctagc ataggagttc tttcatctaa agaactttcc tccccctgca tagcaggggg
       61 attattttta ctgtgacaca taagaaagga gccgcagttc cctcgtggaa ctgcggctcc
      121 tatttatatt actgcttttt ctactcttat gttccccttc ttatggaaaa ggacattcaa
      181 agcctactgc tcttcttttt ttattcgaag ggaagctccc atccagagga gaatcactcc
      241 gctgccgagg agtgtgacaa ctgccggaat aattggagtt tcgtctcctg tctttggaag
      301 tactgccaac ggtaccgggc cgtcctcgat gatagtctcg tctgtgagag gcgcctctgg
      361 agctaacgga acctcattat ctccaatcgt aactgtggag ccgccgccac cgccgcttcc
      421 gccgctatgg cctcctccgc catttccgcc gccgtttcct ccatcgtcct tgacctctgt
      481 caccataaac tgccagtcaa tcttcgaaag agcgcctgca tatttattta ccagattgct
      541 ctctcccagc tctggggtga tggacggatc ctcggttaat ataagagtcg gatccagctg
      601 aagctctacc tggatagaac ctgtctgacc gcccttatag ccgcccagat atacggctct
      661 ctcgccttct gtgccgccag ccgtatcgcc ctgtgtcaga agcgtggaac ctgtcgcatt
      721 gccggtgtag agaagcttct cctcgccgtc ggcattggta taccacacct tcatggaaat
      781 tttctccaga agttcgtcct gaagagcgct ctgctctctc ggaagagcct tcatataaag
      841 cttccatgtc ttgtcgctgt cgttttcaat gtttaaccga tcccggtaaa ttccgcctgg
      901 aaccatattg gtaaagctca tgaaccagtt gccttcctct gcctggccgt cgccgtcccg
      961 gtaaggaatg taggtcatag ttccgtcagt ttctgcaaat ttcagcgttt tcgcctctgc
     1021 agcttcaaat acgccgtcat ccgcgatgtt ctttaccaga tagtctaagg tctgcgcttc
     1081 gtctccgtcc tcagctcctg cgctgaaaat ctcctctgcc gccccctggg tagcctgaac
     1141 cgttgtggca tcaatggtca tggtgtaggt tccattctca tagcctgtgc cattggaact
     1201 gctggaggtt gcaatctgaa taatgccgcc tgtcgggctg ccttcgctgt catactccgg
     1261 ctcgtattcc ttatctacca cgccggatgt aatccgggga ttcatcgtca cgccgtccaa
     1321 aaactgcgga gagctggttc ctgctttcac aattcccata tagtagaggg taaaaattcc
     1381 tttctccccc tccggaatct catttaagag aagccatttt ccctctgcct gactgtactg
     1441 cgtcactgcc tgaaggcccc agcggttctc ctccgtcttc ccgtcggcgt cgccggaggc
     1501 taaaagcact acgttgtttt tgttgaattc aggaaccgcg gcatattctg tttcgccgtt
     1561 ctgggcctgg aacgtcagag gaaaggactc ccagctctga ctgatgacaa cctttgccat
     1621 ggcgtccaca gcgcctttat tcgtgatctg cactgctttc tctgtttttt cccctggctt
     1681 ccagtttttc ggagactcga aggtttcgtc cagagaagtg ttataactgc cagtcataaa
     1741 ttcatttccg gccttcagtt cctgagtcca gctcgcccat gtcccgccga tggcagccgc
     1801 cgaaatcaga gccgccagac ctaatactgc atgtttgcct ttcctcatat cgttctatct
     1861 cctgtccttg cctgtttctg ccaggcgggg gaagcactga actgatgatc agtttttccc
     1921 ctgcccggca gagccagacc gtttttattc tgcctctaat gctgctggct tatcaatact
     1981 gttggctctt aagaaatcat caattaccca gtctttatca ttctctgcaa tctcaagagc
     2041 tgaaccaaat acttctttaa cagcatcaaa ggttgcctga actgtcttag cattgatagt
     2101 catggtgtac tgagcgtcct catagtggaa accagatgaa actgcatcca ctactttcag
     2161 ctctccattc tcatctgcct cataaacctt atctgttgca tcagactgaa tgaacgggct
     2221 catggttaca gatgtgagaa gcgccggagt ctctccttct tcctctacaa tatcactgta
     2281 aacaaagtac agatccagag aatcatcttc ctgctcctga actcctgtta aaacccacat
     2341 attatctgct tcatcaaagg agcctacaga cttagtaatg cccagctctt cgcgtttcgg
     2401 ccaagcctca cttacttcat aaaccgctac attctctccc caatgaacct ctgccgcata
     2461 tacctcattg ccttctgcgt cttcgaaaac cattctctcg ccgtcccact tctgggtaat
     2521 cttagtcatt acggccatat ctacgtttcc ggagttcttt acagatacaa ccttctccac
     2581 tgtctcgcct gggagccagt cttcctccgg cttaaactcc tctacgatat cagaatcgaa
     2641 gtttcctgcc ttaaactcat tgtctacaga taaattctgg ttccagtatg cccatgttcc
     2701 gccaatggcc gctactgctg ccagtcctgc cagtcctaat gctgctctct ttttcatttc
     2761 ctgttcctct tccctttccg ttaatgccta ggcctctgtc ttttcctctt tcttcttatc
     2821 cgggaaaaac atatccaggg caattcccag tacgataatg gctgccatca caataatgac
     2881 gcccatattt ttactgtaat ttacaaaata acctgcgtat ggaatgctca ccttccacac
     2941 ctttccgata acctcatcgt agtccaccgg attcggatcc tccgtctcgt tggcgtctcc
     3001 ctttgtgaca aagttctggg aaagctcgct tttttctact acccggtgag tcaccatgcc
     3061 gtcctctcct gcctggaagg taatagcgtc tcctacgtta atgtcagcga aatctgcctc
     3121 cttataataa atgacgcttc ccacatgata ggtgggctcc atacttccgc tgagaaccac
     3181 gaccggatgg tatcccgcca gcatgggcgc cgctatcaga aggtagcagg caatgcaggc
     3241 gtatacaatc caggtcagaa tatttacaaa tcctttgatc agtctcatat gttaagtcct
     3301 gttatgtatg attttactta aaagccagac tctatttcag gatattttcc attaactctg
     3361 ccggagcggt tgtccactct gcttcaacag catctggagt agcctgaaca gcctctgttg
     3421 tgatgtttaa agtatatcct gcatcagaat agccctttgc attctcgtct gtctttgttt
     3481 caagagtcat atagaaatcc ttatctgtct gtccctctgc aatctctgct aattccttct
     3541 gagcctcttc ttcagttgta gccttcattt cgttccatgt atctgcatta aagtcgggct
     3601 cgtctgcacc cttctctact gcaatgtagt agtacttatt tgcaatcaga cccatatctg
     3661 ttttctcatc taacttaata gagttcagta aattaacggt tgcttctccg ccctccagct
     3721 tatcgcagaa ataccagtaa ccgtcttctg caagatacca tttatcctgt ttttctacag
     3781 cgtctaactg gatattagcc tcatccagat ttttgtgtac tactgttgaa aaatcattta
     3841 aaggatttcc atcttcattg gtaagtcttt cagatacttc taaaaatgcc agcggatcct
     3901 tttcagaagc ccactctcca aaaagctgct ctggagctgc tttatacgcc cagttctcat
     3961 ccatcttaac acgtactaaa actgcgcctg ttcctgtatt ctttacagtg atcttcttct
     4021 ctacctctgt tccaggagcc cattcagaac caggattgaa cttctctgtt gtatttaatc
     4081 cgtacatacc gtctgttgtc agtttgttat gaatggttgt atcctgtgta aagaatgccc
     4141 aggttccgcc aactactgct aaagctgcaa gtccgccgat tgctgttaat ttcttattca
     4201 tgtttctacc tcctaaaata tctcccttta ttcgctgtca acatttattc tgctgaaagt
     4261 gttcctaaaa aattccaagc ccattttcct tcttttgccg cctgaacagc catagggccg
     4321 aactctgctt cgacggcgtc ctctgttgcc tgcactgtct gggcaatgac agataaagta
     4381 tattctgcct tggcatatcc gctgtccatt ggatttccat cttcatctgt ttctaatccg
     4441 attgtagaac gaaaatactt aacttcttct cttatatcgt ccggtaaatc agcctcagaa
     4501 acttcctgtc cacccgcatc cggcgaaaac tgaatccaat cgctgctgtt ttcatctggc
     4561 tgctcttccg ttgtagcata aaactttttc tctaccatac ggcccatatc ggcattttca
     4621 gtcagacgta ttttttccaa aagcggagga gtttctgtct ctccctctaa gatactggtg
     4681 taataatagc acccgtcttt ctggttatac tcccagcctt ttcccagatt aaatgttttc
     4741 tctacaaccg tttgatctcc tgcgatttct ccatctgaag aatcttcctg ataaatatct
     4801 gttaaatcat ttccttcatc ttcagaactt tctcccggaa gaagctcgtt attctcatcc
     4861 gtttttctgt tagtaacaga attttcacgg ccgtctgccg ctgtccatgt ttctacaaac
     4921 cagacgcggg caactgccgg aacgtttcca tcattgacga ctcgaacctc ttttttaact
     4981 tctgctcctg gctcccagtc agtaatcggt ttgaaatctt catgtactgt cgtatcaaat
     5041 tttcctactg aaagggcgtt gactgcttcc agattctggt tgaagtatgc cagggagccg
     5101 ccaactgcaa atactgcagc gagtcctgcc agggcagcta tatgtttctt tttcatgatt
     5161 cacatcctcc tgtcactctc cccacctttt taagacgggg gattgatcaa cctttactct
     5221 gttgtattaa gcagttcgtt ccattcgcat acagataaat cagcgtcttt caggtcttcc
     5281 gcccataatg cagctgaagt tttatctgcc ggaacagcct ctgcttcgat ggttatctcg
     5341 tactctgcgt tgctgtaatc agcctcatgg ccatcatttg aaacatctgt ggaaagagtt
     5401 aacgaatcca taattggatt tgtttttgaa ttctctgtcc cttgttttgt caaaatcttg
     5461 ttgtagtaat agtattcttc gccagcaaac cactctgaag attcctcatt aacccaatac
     5521 tggctccaat tttttattac cttctcattg tccagctgat cttcagcgtt ttcttctgtc
     5581 ttcctccatg tttcagccaa gtctttcgga atgcggagaa gcatgtccct atctcccgta
     5641 ttctcgaaat acggcttctt cgttaccgtt tcacctggca ggaacgaact aaactgtaca
     5701 aaatcttctt tcagcataac tgccgtatgt tttgtggaaa gctgattttt aatggtattt
     5761 gtatctgtgt acacagccca tgtggtgctg acggacactg cgcaaattcc tccaatcagg
     5821 gcgataccta atcttttata taatttcata aattagttac ccccttccac ccactcaagc
     5881 tgagaagtat acttatttgt ttcccagttt gctggctgcg tattttcaag ccttactccg
     5941 cttccgaaaa cagtatctac agcttttatg ttcagattat aatcatcgct ggactgtact
     6001 gcttccacct gaaaatgaag ctcgtattct gcgccgctat actctgactc ctgagaagac
     6061 acattactga agtctactgc cgtaagcaat ggcttcgttt gatctgtagc gctgccattg
     6121 gccgcttcta acacatatct gtaatagtac cagccgtcgt ttcccagcgt ccattcatct
     6181 tcagaaaaca tattttccat tgaattttcc agctgcgtat ctttaaactt tttagcaacg
     6241 tcatgtccat cagaattctg gctggataac agctcgttct ccttctccca ctgctctgca
     6301 taagctactc tgataaatac gtctgcggtt ccctgatttt caaaagatac caccttttgt
     6361 ttcttagaac cttcagtctc tccaactata tcgtcaatac ttacttcaac agttggggtt
     6421 ttcagagtat tcttcactgc cagcttgtgc tggacaacag cccctgttcc tccaattccg
     6481 gctaccgcca ctgtcaggag agcgattcct gacagtttta ctgcatttgc cttttttcca
     6541 cttttaagca attaaatcac cctcctcctg ttcaagttct gttttcttct tagtcagtcc
     6601 cagcttggaa gctgtcttgg cagcctgctc ggctaaatca ttagtaaatg gtgtgcttgt
     6661 atctcccttt gtcttattgg ttacagaaaa agcgtcgtgg aagaagtctt tatgtaccgg
     6721 agtgttcgtt acacggacaa tcaaatcctg tcctggaaga actttaaagt ttccgtcctc
     6781 tgccactact ccggctgtct ccggcttcgg atttccattt ccatcgtttt catatacaac
     6841 gatagaactc tgctcatatt ccatcggcac aatctcgtga acattgaacg tcttctcgcc
     6901 ttctgtgata actgtaccag tcatctctcc gtcttttaaa gctacggaag atttaaagcc
     6961 gtttgttcca tctgcggtct gctcctgaat ctgaataatg aactcctgat ccggactgcc
     7021 tgcgagaggc gtttcattat catcaatctc aaccagcttc tgaactacga agcggccttc
     7081 tggcagtatc tggataactg ggtgaggata ctcaaacgca ttatcgccag cataagttac
     7141 accgttatag ctaaaggaaa gtgtcgcctc tgtatttgag tagaaaccaa gttcattctt
     7201 gtccgcatgt gtgcctgtac ctgcatctgg agtattcgga taagctccat tttgagcata
     7261 ataatccatt gccgcctgtg ttggcttaat ccgaaccttt acctggtagg taactccctc
     7321 ttcaaatgcc tcctttccgg gtctacagag cagcacttct g
//
LOCUS       DBMDUW010000082         7088 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_4511_length_7088_cov_2.765421, whole genome shotgun sequence.
ACCESSION   DBMDUW010000082 DBMDUW010000000
VERSION     DBMDUW010000082.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 7088)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 7088)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7088
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4511_length_7088_cov_2.765421"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..139)
                     /locus_tag="ACZPCR_11310"
     CDS             complement(<1..139)
                     /locus_tag="ACZPCR_11310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HIR1231485.1"
                     /translation="MNEIIKNIENAQLRTDVAEFHVGDTVKVYAKIKEGNRERVQVFE
                     GT"
     gene            complement(227..958)
                     /locus_tag="ACZPCR_11315"
     CDS             complement(227..958)
                     /locus_tag="ACZPCR_11315"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024811.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HIR1231486.1"
                     /translation="MSLDLFQTLADVNARIPEIWKEILGEQYTDRRARAGAEAIVSAY
                     PKVLKKSFSENGFCDMEEIYRRCAREALRITGFGNGSFSVTEEKMTQVILKNHSLAPL
                     YEDVVSVLRELKKRFRLVLSSDASPLMAEGVLKRLEEAGITFEKVFLSDELKAWKGGP
                     DRRFFSEVYRELKVKPEEILHIGDSVSDISGASKSGLHSCLISRDYRPYKGKAQPDYR
                     INGLSEIAKLLRKIPEKGLAEADNL"
     gene            complement(989..1720)
                     /gene="trmD"
                     /locus_tag="ACZPCR_11320"
                     /pseudo
     CDS             complement(989..1720)
                     /gene="trmD"
                     /locus_tag="ACZPCR_11320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583613.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
     gene            complement(1755..2267)
                     /gene="rimM"
                     /locus_tag="ACZPCR_11325"
     CDS             complement(1755..2267)
                     /gene="rimM"
                     /locus_tag="ACZPCR_11325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567739.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HIR1231487.1"
                     /translation="MEQFLRVGVITSPHGIRGEVKVFPTTDDINRFKKLKEVYLDTGK
                     ERLSLRVEQAKFFKGMAILKFREFNSINEVEPFRKKDLLVSREHAVQLAPNENFIVDL
                     IGLAVVTDEGEEFGTVKDILQTGANDVYVITGKDGKEYLFPSIKECILDVDLDKGQVL
                     VHILDGLLDL"
     gene            complement(2329..2556)
                     /locus_tag="ACZPCR_11330"
     CDS             complement(2329..2556)
                     /locus_tag="ACZPCR_11330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HIR1231488.1"
                     /translation="MKELVEVIAKALVDNPDEVAVTESVKDDEIVVELTVASSDMGKV
                     IGKQGRIAKAIRSVVKAAASKEDKKVIVEIQ"
     gene            complement(2641..2880)
                     /gene="rpsP"
                     /locus_tag="ACZPCR_11335"
     CDS             complement(2641..2880)
                     /gene="rpsP"
                     /locus_tag="ACZPCR_11335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008398347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HIR1231489.1"
                     /translation="MVKMRLKRMGQKKAPFYRIVVADSRSPRDGRFIEEVGYYDPNTE
                     PSTIKIDEEAAKKWLATGAQPTETVGKLLKIAGIQ"
     gene            complement(2969..4327)
                     /gene="ffh"
                     /locus_tag="ACZPCR_11340"
     CDS             complement(2969..4327)
                     /gene="ffh"
                     /locus_tag="ACZPCR_11340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HIR1231490.1"
                     /translation="MAFESLADKLQNVFKNLTGKGRLSEADVKAGLREVKMALLEADV
                     SFKVVKQFINSVQERAVGQDVLNGLNPGQMVIKIVNEELVKLMGSEMTEIALKPANEI
                     TVIMMAGLQGAGKTTTTAKIAGKLKAKGRKPLLAACDIYRPAAIDQLRINGEKQGVPV
                     FSMGTGHKPVNIAKAAIEHAAKNGDNVVILDTAGRLHIDEDMMNELVEIKEQIAVDQT
                     LLIVDAMTGQDAVNVAGMFNDKIGIDGVILTKMDGDTRGGAALSIKAVTGKPILYVGM
                     GEKLSDLEQFYPDRMVSRILGMGDIMSIIDKATAVIDEEKAKALSQKIKKAEFDYNDF
                     LDQMHQIKKMGGMASIMNMMPGMNQLKGVDLDGNEKMMDRVEAIILSMTKEERANPDL
                     LNPSRKKRIAKGAGVDIAEVNRIVKQFEQMKKMMKQLPGMMGGKRRGGLGGLMGKMKL
                     PF"
     gene            complement(4364..4705)
                     /gene="ylxM"
                     /locus_tag="ACZPCR_11345"
     CDS             complement(4364..4705)
                     /gene="ylxM"
                     /locus_tag="ACZPCR_11345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006780718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048500 - signal recognition particle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxM family DNA-binding protein"
                     /protein_id="HIR1231491.1"
                     /translation="MEKIVEQTLLYDFYGELLTDHQKEIYEDAVFNDLSLSEIANEQG
                     ISRQGVHDLIKRCDRTLNGYEKKLQLIHKFQQTRELVAEIHKLTKQFKETGDEAFIDR
                     IGEISSDIIKL"
     gene            complement(4787..6886)
                     /locus_tag="ACZPCR_11350"
     CDS             complement(4787..6886)
                     /locus_tag="ACZPCR_11350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009261881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231492.1"
                     /translation="MYRETELRALYDRLKAQYPQYQLDFSGDCLTIARLRSRAVINCE
                     GAKLYTGETLYDQFTSEEVNNPDDLYELIELFFLELQRSGMESGNETYRSAQKQAARG
                     TTRLMLSMSLFLTICLVSLLITRNRWWIAPILILPFVSFVPLALIHKRAFQTHWVCPT
                     CGEALPLDKQSRFPKMEYVFQCPCCGQILEQPSELEPVHPESTMPKKQLEPPCDLPKP
                     GKKWPCLLAGSITAALSLFLFPLLFVSDEPLDPLGVGIAAALLLLLIGLGMVLIFCRH
                     RELEAIRQPIVAVRERNIVTVFGMILWLLGFIMMLLSVIVSGTPPFEAVYTIVTASIG
                     LPFMVLGIWMLSAGRSRSLLIFQDNSVLYTSSFGKQKMFAPGQITAVQLTASRSIRLL
                     DSNGKNLVSVETNMKGIPRLAEWIECLDLAASLTHAMEKQAEQEAKAEGTVQWREEYR
                     TRWHAHMKAVRAGKWLVLLFFAAGTLAPLPLALFADIKFRAAMAIAAIAPIPFLVFCI
                     VFAPVLLFDDPPKNATPEWNTMHIKMPLIPSLLLALLYMGQVHYFWEGWVLQEVDDSW
                     FSLVRILVIGVFLTVMLLVRTPKRLRLGAGFFMGLIGFCTAFGFHYYINTALCGPARH
                     YPAVIADSHAGDPDDEEDHCTLTVIMDDGRKADLAVLREIYEQALRGEPFDLCHWESP
                     LGAAFLDIHAPKEDDEE"
BASE COUNT         1705 a         1893 c         1549 g         1941 t
ORIGIN      
        1 cagttccttc gaaaacctgg actctctcac ggtttccctc tttgatctta gcgtatacct
       61 taactgtatc gcctacgtgg aactcagcta cgtctgttct taactgtgcg ttctcaatgt
      121 tcttaataat ctcgttcatc taagtgaacc tcctttaaaa tctttgatgt tcttaataca
      181 tatcgtaaca gaggaccatc tctttatttc acaggtataa attctatcac aaattgtccg
      241 cttctgcaag acctttttca ggtatttttc gcagcagctt tgcaatctcg ctcagcccgt
      301 taattctgta atccggctgc gcctttccct tgtagggccg gtagtcccgg ctgatcaggc
      361 agctgtggag gccgcttttt gaggcgcctg aaatatcgct tacgctgtcc ccgatgtgga
      421 gaatttcctc cggcttcacc ttcagctctc tgtatacctc ggagaagaaa cgcctgtcag
      481 gccctccctt ccaggctttt aattcgtctg ataaaaagac tttctcaaag gtaatcccgg
      541 cctcctcaag ccgttttaga actccctcag ccataagggg gctggcgtcg ctggaaagca
      601 caaggcggaa gcgttttttc aactctctga gaacggagac cacatcctca taaagcggag
      661 ccagactgtg gtttttaagg ataacctggg tcatcttttc ctctgtcaca gaaaaggagc
      721 cgtttccaaa acctgtaatc cgaagggcct ctctggcgca gcggcggtaa atttcttcca
      781 tatcgcagaa gccgttctca gaaaacgatt tttttaaaac cttgggatag gcgcttacaa
      841 tggcttccgc ccctgccctg gcccggcggt ctgtgtactg ctcccccagg atttccttcc
      901 agatttccgg aattctggca ttgacgtctg caagggtctg aaacagatcc aggctgatta
      961 cctgatagga ggcccggcgc gccgtcctct gctcatgaaa gacagaatcg gcaaatttct
     1021 gttctgcgtc tgtcagacag gcgtccttca tcagatcagg ccgccgttca atggttctgc
     1081 ggatggactg ctctcttctc caggcgtcga ttttcctgtg atctccgttt aacagtacct
     1141 gagggacctg ccttccctga aaaacctcag gacgcgtata ctggggatac tctaacagat
     1201 tgtcgtggaa ggattcaaac tctgccgact cgtcgttatt taatactcct gggacaaggc
     1261 gggagatgca gtcgatcatg accatagcgg gaagttctcc tcctgtcagg acgtaatcgc
     1321 caatggacag atagtctgtg acaattaagt ccaaagcccg ctcgtcaatt ccctcatagt
     1381 ggccgcagag aaagaccaga tcctcctcct ttgccagatc ctctgcgatt ttctggctga
     1441 acacctttcc ctggggagtc atataaatta ccctgggccg ccttcccagg cgggcggcca
     1501 gatcctcgta ggcagaaacc acaggaccgg gctgcattac cattcctgca cctccgccgt
     1561 agggatagtc gtccacatga ttgtgcttat cctgggaaaa atcccggata ttcactgctt
     1621 ctgccgatat cagccctttt tctatggcgc ggccgataat gctgttattt aatccatcca
     1681 tgatcatctg cggaaataag gtcagtatat gataattcat cgcgtcctcc tgtttaaaaa
     1741 gacggcccgg gactttacag atccagaagg ccgtctaaaa tatgtaccag aacctgtcct
     1801 ttgtccagat ccacgtcaag aatgcactcc ttgatagatg ggaacagata ttcctttcca
     1861 tcctttcccg taatcacata gacgtcgttg gcgcctgtct gaagaatatc ctttaccgtt
     1921 ccgaactcct ctccctcgtc agtcaccaca gcaaggccga tgagatctac gataaagttt
     1981 tcattaggcg ctaactgaac cgcatgctct ctggatacga gaagatcttt tttgcggaat
     2041 ggctccacct cgttgatgct gttaaattcc ctgaatttta aaatcgccat gcccttgaaa
     2101 aatttcgcct gctccacgcg gagagaaagg cgctcttttc cggtgtccag atatacttcc
     2161 ttcagtttct taaagcggtt gatatcgtcg gttgtaggga acacctttac ctcgccgcgg
     2221 atgccgtgag gagaggtaat gacgcccacc cgtaaaaact gttccatagt cgtctccatt
     2281 ttctgaaata acaaaagccg tctaccatga aggccggcgg cttcttcgtt actgaatctc
     2341 tacaataact ttcttatctt cttttgatgc ggctgctttc acaacggagc ggatcgcttt
     2401 cgcaattctg ccctgttttc caatcacctt acccatatcg gaagaagcga ctgtcagctc
     2461 aactacaatc tcgtcatctt ttacagattc tgtaactgca acctcatctg ggttgtctac
     2521 cagcgctttt gcaatcactt ccactaattc tttcatacca ttcacctcgc agaccgcact
     2581 cggaactccg aagccggcct atgaaaaatg cctttaaaag gcatttttca tacaagctat
     2641 ttactggata ccagcgattt ttaaaagctt tccaacagtc tctgttggct gagcgcctgt
     2701 tgctaaccac ttcttagcag cttcctcatc gatcttgata gtgctcggct ctgtgttcgg
     2761 atcgtagtag cctacctctt cgatgaatct tccgtctctt ggggatctgg aatctgcaac
     2821 gacaattcta tagaaaggtg ctttcttctg acccattctt tttaatctca tctttaccat
     2881 tgtaatttac ctccttgtgt atttggaaac ttatatagaa aatgcatctg catttgctaa
     2941 ccttttcttt tcattcaaat atttgatttt agaagggaag cttcatcttt cccatcagtc
     3001 cgccaagtcc tccccggcgt tttccgccca tcatgcccgg cagctgcttc atcatctttt
     3061 tcatctgctc aaactgcttg acaatgcggt ttacttccgc gatatccacg cctgcccctt
     3121 tggcaattcg tttctttctg gaaggattca gcaaatcagg attggctcgc tcttctttcg
     3181 tcatggagag gataatcgcc tccacccggt ccatcatctt ttcattgccg tccagatcca
     3241 cgccctttaa ctggttcatg ccgggcatca tattcatgat gctggccatg ccgcccattt
     3301 ttttaatctg gtgcatctgg tctaagaagt cattgtaatc aaactctgcc ttcttaattt
     3361 tctgagagag agctttcgct ttctcttcgt caatcacagc agtggcctta tcaataatgg
     3421 acatgatatc gcccattccc aggattcggg aaaccatacg gtccggataa aactgctcta
     3481 aatcagagag cttctcgccc atacccacat agagaatcgg cttgcctgtt accgctttga
     3541 tagaaagagc tgctccgcct cgcgtatcgc cgtccatctt ggtcagaata acgccgtcga
     3601 tgccgatttt atcgttgaac atgcccgcga catttaccgc gtcctgtcca gtcatggcgt
     3661 ctacaatcaa aagcgtctga tccacagcaa tctgttcttt aatttccacc agctcgttca
     3721 tcatgtcctc gtcaatgtga agacggccgg cagtatcgag aatcaccaca ttgtcgccgt
     3781 ttttagccgc atgctcaatg gctgccttgg caatatttac cggcttatgg ccagttccca
     3841 tggaaaatac gggaacgccc tgcttttcac cgttgattct cagctggtcg atggctgccg
     3901 gacgatagat atcgcaggct gcaagcagag gctttctgcc tttggccttg agctttccgg
     3961 caatcttcgc tgtggtagtc gtcttacctg cgccctgaag accggccatc ataatgacgg
     4021 tgatttcatt ggcaggcttt aaggcaatct ccgtcatctc ggatcccatc agcttaacca
     4081 gctcttcatt tacaattttt attaccatct gtcccggatt cagaccattt aagacgtcct
     4141 gtcctaccgc cctctcctgc acagaattga taaactgttt tactacttta aagctgacgt
     4201 ccgcttccag caaagccatc ttgacttccc tgagcccggc ctttacatca gcctctgaca
     4261 gacggccttt tccagtcaga tttttaaata cgttctgcag tttgtctgca aggctctcaa
     4321 aagccatccg gaaaacctcc tgtcccgcca cagtgtcctg tggctacagc ttaataatgt
     4381 cactggaaat ctcgccaatg cggtcaataa aagcttcgtc ccctgtctcc ttaaactgtt
     4441 ttgtcagctt atggatttct gccaccagct ctctggtctg ctgaaatttg tgaatcagct
     4501 gaagcttttt ttcgtatccg ttcagagttc tgtcacaccg cttaatcaga tcatggacgc
     4561 cctggcggct gattccctgt tcattggcaa tctcgctgag agataagtcg ttaaacactg
     4621 cgtcttcgta gatttctttt tggtggtctg tcagcagctc gccatagaaa tcatagagaa
     4681 gtgtctgctc cacaattttt tccatttcca atcacctgca ttataatatc ataggcaggc
     4741 tggggtgtca agtatttttt ctttacacta tattttatat atttctttac tcttcatcgt
     4801 cttcttttgg agcatggata tccagaaacg ccgctcccag cgggctttcc cagtggcaga
     4861 gatcaaacgg ttcgccgcgc agggcctgtt catagatttc tctcagaacc gcaaggtcgg
     4921 ctttcctgcc gtcgtccatg ataacagtca gagtacagtg atcttcttca tcatctggat
     4981 cgccggcatg gctgtctgcg atgactgccg gataatgtct ggccgggccg cacagggctg
     5041 tattgatata ataatgaaag ccaaaggctg tgcagaagcc aatcagcccc atgaaaaaac
     5101 ctgctcccag acgcaggcgt tttggggtac gcacaagcag cataaccgtc agaaatacgc
     5161 cgataaccaa tatccgcacc aggctgaacc agctgtcgtc cacctcctga agaacccagc
     5221 cttcccagaa gtagtgaacc tgtcccatat agagaagagc tagaagcagc gaaggaatca
     5281 gaggcatttt tatgtgcatg gtgttccact caggcgtagc gtttttgggc ggatcgtcaa
     5341 aaagcaggac aggagcaaaa acgatgcaga acactaaaaa tggaatgggg gcaatggctg
     5401 caatcgccat tgcagcgcgg aattttatat cggcaaagag agccagaggc agcggagcaa
     5461 gcgtaccggc agcaaagaaa agcaaaacca gccattttcc tgcccggaca gccttcatat
     5521 gagcgtgcca acgggttctg tactcttccc gccactggac agttccctct gccttcgctt
     5581 cctgctctgc ctgcttttcc atggcatgag tcagagaggc tgcgagatct aaacactcaa
     5641 tccactctgc cagccgggga atgcctttca tatttgtttc caccgaaacc agatttttac
     5701 cattgctgtc cagcaggcgg atggaacggc tggcagtaag ctgcacagca gttatctggc
     5761 ctggcgcaaa cattttctgc tttccaaagc tgctggtata cagaacagaa ttatcctgga
     5821 atatcagcag gcttcggctg cgccctgctg acagcatcca gattccaagc accataaacg
     5881 gcaggccgat ggaggcagtg acaattgtat aaacggcctc gaacggaggt gttccagata
     5941 caataacgga aaggagcatc ataatgaaac cgagaagcca taaaatcatt ccaaaaaccg
     6001 tcacaatatt ccgttcccgt acggcgacga ttggctgccg tattgcttcc agctccctgt
     6061 ggcggcagaa aatcagtacc atccccagtc cgataagcag caaaagaagc gctgccgcta
     6121 ttccgactcc cagcggatcc agcggttcat ctgagacaaa caaaagcgga aaaaggaaca
     6181 gagacagagc ggctgtaata ctgccagcca gcagacaggg ccattttttt ccaggtttag
     6241 gcagatcaca gggcggctcc agctgctttt tcggcatagt gctttccgga tgaaccggtt
     6301 ccagttctga cggctgttcc agtatctggc cgcagcaggg acattgaaat acatactcca
     6361 ttttggggaa acggctttgc ttatctaagg gaagagcctc tccgcatgtc gggcagaccc
     6421 aatgggtttg aaacgcgcgc ttatggatca gagccagcgg cacaaaggac acaaacggga
     6481 gaatcaagat cggtgcaatc caccagcggt ttcgggtgat gagaagcgaa accaggcaga
     6541 tcgtaagaaa aaggctcata gaaagcatca ggcgcgtagt tccccgggct gcctgcttct
     6601 gagcagaacg ataggtttca ttcccgctct ccatgccaga acgctggagt tctaaaaaga
     6661 ataattcaat cagctcataa agatcatcgg gattgtttac ctcctcactg gtaaactgat
     6721 cgtacagcgt ctcacctgta tacagctttg ccccttcaca atttatcaca gctctgctgc
     6781 ggagtctggc gatcgtcaga caatcgcctg aaaagtccag ctgatactgt ggatactgtg
     6841 ctttcaggcg gtcataaagg gctctcagtt ccgtttcacg atacataggc aggttctcct
     6901 taaaatacag aatatgacag atattgtcta ttatacttga tttcgctaaa gaattaaaga
     6961 aatttttcag taaatacttg tcaagaaaac ttttttatgc tagaatacaa tcgttctgaa
     7021 tcatatgggg atatagctca gctgggagag cgcttgaatg gcattcaaga ggccgtgggt
     7081 tcgagtcc
//
LOCUS       DBMDUW010000083         6952 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_4604_length_6952_cov_2.698876, whole genome shotgun sequence.
ACCESSION   DBMDUW010000083 DBMDUW010000000
VERSION     DBMDUW010000083.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 6952)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 6952)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6952
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4604_length_6952_cov_2.698876"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..4409
                     /locus_tag="ACZPCR_11355"
     CDS             <1..4409
                     /locus_tag="ACZPCR_11355"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003499696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HIR1231493.1"
                     /translation="PRLIHKQNIYGLEKGIKDQLFPGKRVTIKIQEKFKLSEQYTPEK
                     LLMVYKDSILMELKNYSILLYNMFRKAECSFPKHDVMEMVLEDTMIARDKTAELKRVL
                     EKIFTERCGLPLEIDEEYRARQKKTLDPGYDAYLDAMAASGDGAEFPGAEGEDTPFYD
                     ASVYAPEAEAELAPGRLKAAVPAADGGKVQKTGRQDSGKKEAGKKEINKKEFGKKDFK
                     KREGGRFGGYRRSEDPDVLYGRGFDDETIEIHQIEGEIGEVAIRGKILTCENRELRSG
                     KQLFIFTITDFTDTIGVKIFAKEEAVDDLKAATAPGQFVRLKGVATIDRFDGELTLGS
                     VVGIKKCEDFTGKRMDNSPVKRVELHCHTKMSDMDGVSEVKDIIKRAKKWGMDAIAVT
                     DHGCVQAFPDANHAVEKGDGFKVLYGVEGYLVDDMKQLAENETGQSLDHTCVVFDIET
                     TGFSPIKNKIIEIGAVKVENGKITDKFSTFVNPEVPIPFEIEKLTSISDNMVLNAPTI
                     EQVLPKFLEFCGDAVMVAHNASFDMSFMKHNALLLGMTFEPAILDTVSMARFLLPNLH
                     RFKLDTVAKELKISLENHHRAVDDAGATAEIFVKFMEMLKQRGIENLTQLNEHSQMSV
                     ETIRKMPTNHIIILAKNDIGRINLYRLVSDSNLIYYAKRPRIPKSEIMKYREGLIIGS
                     ACEAGELYQALLRGVPEAEINKIAEFYDYLEIQPLGNNGFMLRDEKSVVKSEEDLKDL
                     NRKIVELGERFNKPVCATCDVHFLDPEDEVYRRIIMAGKGFKDCDDQPPLYFRTTEEM
                     LREFEYLGSDKAEEVVITNTRRIAAMCERIAPVRPDKCPPVIPNSDEMLRNICYNRAH
                     EMYGENLPKIVVERLERELNSIISNGFAVMYIIAQKLVWKSNEDGYLVGSRGSVGSSF
                     VATMSGITEVNPLSPHYYCTECHYYDFDSEEVKKFSGMAGCDMPDRLCPVCGKPLKKD
                     GFDIPFETFLGFKGDKEPDIDLNFSGEYQSRAHDYTEVIFGKGQTFRAGTIGTLADKT
                     AFGYVKKYYEERGERKRGCEINRIVTGCVGVRRTTGQHPGGIIVLPHGEEIYSFTPVQ
                     HPADDMGTKTITTHFDYHSIDHNLLKLDILGHDDPTMIRMLQDLTGLDPVRDIPLDSK
                     EVMSLFQSTEALGITPDDIGGCPLGALGVPEFGTDFAMQMLLDTKPKYFSDLVRIAGL
                     AHGTDVWLGNAQTLIQEGKATIQTAICTRDDIMVYLIGMGLEEGLSFTIMESVRKGKG
                     LKPEWEEEMTAHGVPDWYIWSCKKIKYMFPKAHAAAYVMMAWRIAYCKVFYPLAYYAA
                     FFSIRASGFSYELMCQGREKLEHHLADYRKRLDSLSKKEQDTLRDMRIVQEMYARGYE
                     FTPIDIYKASARNFQIIDGKLMPSLSSIDGLGEKAADGIVFAAEDGPFLSKEDFINRS
                     KVTKTVADLMADLGLLRGLPESNQLSLFDLAL"
     gene            4430..5644
                     /locus_tag="ACZPCR_11360"
     CDS             4430..5644
                     /locus_tag="ACZPCR_11360"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HIR1231494.1"
                     /translation="MKYDFETVLDRYDNGSVKWNLMKKKKPQVGRGVVPFSIADMEFK
                     NPPEIIEALKEYLDTAVLGYQTAEPSWYEAVTGWTKRRYGWETRPEWFYTTPGVVNAL
                     YHGVLAFTEPEDGVIVMPPVYYPFYKAVETNGRRTVRCPLKEGRELSYTIDFDRLEAL
                     ASDPKNTLLILCNPHNPVGRVWTRQELLMVSQICLRHHVFVISDEIHCDLIMPGHTFT
                     SFASLSEENAANTMTCIAPSKTFNLAGLEASCVILPDRERRHQLKAEMSRVSYEGRVN
                     ALGYKAMEAAYTRCDQWLSQAIQAIHSNHRLLTEFLKEHCPDVKAAPLEGTYLQWLDL
                     RALGWTPKEQESIMEEADLFFDEGGMFGPEGEGFERMNLACPQTVILDGLGRFSQVVN
                     RRKRGGGDDHRG"
     gene            5628..6533
                     /locus_tag="ACZPCR_11365"
     CDS             5628..6533
                     /locus_tag="ACZPCR_11365"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: protein motif:HMM:NF012301.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0071111 - cyclic-guanylate-specific
                     phosphodiesterase activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HIR1231495.1"
                     /translation="MIIEDNGSLNMADTLLVVDDVELNRAILAEIFQDSYQIEEAENG
                     RAALEKLISGRERFCGVLLDVMMPEMDGISLLKILQGSHMTEEIPVFLITSETSPALW
                     KEAYSLGIMDLIPKPVIPYIVRYRVDSVVRLFQAKRRLGSQVERQKDELLKKAEEMYR
                     LSIGMAESLANVIEFKSDESSSHIRRIHEITMALLQDTRLGNGLSRRDIEQIGLAAIM
                     HDVGKIAIPDHILNKPGRFTPDEFELMKSHTLKGVTGNLSMKPLYQLTSRQVELLRAG
                     QLEEARELMADIDRAYEETAGALKE"
     gene            6538..>6952
                     /locus_tag="ACZPCR_11370"
     CDS             6538..>6952
                     /locus_tag="ACZPCR_11370"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231496.1"
                     /translation="MVRQNSADRKGIRHGKKQRRIRETLLRIRKSLVLLVLFAAISTV
                     SFHVIQNNLLDHARVMGDGLALSYSVEEEKNITAYQVLMNMETNYLDQFLESKPSEEE
                     LKAWLSIFYKNTGEALGKNSILPYAVINGAIIPAIE"
BASE COUNT         1857 a         1590 c         1986 g         1519 t
ORIGIN      
        1 gtcccagact gattcacaag cagaatattt acgggctgga gaagggaatt aaggatcagc
       61 tgtttcccgg aaagagagtc acgatcaaaa ttcaggaaaa atttaaatta tccgaacagt
      121 atactcctga gaagcttctg atggtctaca aggacagtat tttgatggag cttaaaaatt
      181 acagcattct tctctacaac atgttccgca aagcggagtg cagttttccg aaacatgacg
      241 tgatggagat ggttttggaa gataccatga tcgccagaga caaaacggca gagctgaagc
      301 gggtgctgga gaagatcttt acggagcggt gcggactgcc tctggaaatt gacgaggagt
      361 accgggcccg ccagaagaaa accctggatc cgggctatga cgcctacctt gacgctatgg
      421 ctgcctctgg agacggggca gagtttccag gagcagaagg ggaggacacg cccttttacg
      481 atgcttccgt ctacgcgccc gaagcagagg cagaactggc gccaggccgg ctgaaagcgg
      541 cagttccagc ggcagatgga ggaaaagtcc agaaaacggg gcgtcaggat tctggtaaaa
      601 aggaagccgg caaaaaagag attaataaaa aagagttcgg taaaaaggat tttaagaaga
      661 gagaaggcgg ccgcttcgga ggataccgcc gttccgagga tccggacgtg ctctacggcc
      721 gcggctttga cgatgagacc atagaaattc atcagatcga gggagaaatc ggcgaggtgg
      781 caatccgcgg aaaaatcctg acctgcgaga acagagagct tcggagcgga aagcagctgt
      841 ttatctttac cattactgat tttactgaca ccatcggagt gaaaattttc gccaaagagg
      901 aggcggtgga cgatttaaag gcggccaccg ctccaggaca gttcgtccgc ctgaaaggag
      961 tagctactat cgaccggttc gacggggagc tgaccttagg atcggttgtg ggaatcaaga
     1021 agtgcgagga tttcacggga aagcgcatgg acaacagtcc ggtaaagcgt gtggagcttc
     1081 actgccatac aaagatgagc gatatggacg gcgtttccga agtgaaggat attatcaagc
     1141 gggcaaaaaa atggggcatg gacgccatcg cagtgacgga tcacggctgt gtccaggcct
     1201 ttcctgacgc caaccatgca gtggagaaag gagacggttt caaggttctc tatggagtgg
     1261 agggctatct ggtagacgat atgaagcagc tggcagagaa cgagacggga cagtccctgg
     1321 atcacacctg cgtggtcttc gatatcgaga ccaccggctt cagcccgatt aaaaataaaa
     1381 ttatcgaaat tggcgcagta aaagtggaaa acggaaaaat tacagacaaa ttttctacgt
     1441 tcgtcaatcc ggaagttccg attccttttg agattgagaa gctgacaagc atcagcgaca
     1501 acatggtttt aaatgcgccc actattgagc aggtgctgcc aaagtttctg gaattctgcg
     1561 gggacgctgt catggttgcc cacaacgctt ctttcgatat gagctttatg aagcataacg
     1621 ccctgctcct gggaatgacc tttgagcctg ccattctgga taccgtttcc atggcccggt
     1681 tcctgctccc caatcttcac cggtttaagc tggacacggt ggccaaggaa ttgaaaattt
     1741 cccttgaaaa tcaccaccgg gcagtggacg acgcgggagc tacggcagaa attttcgtga
     1801 aattcatgga aatgttaaag cagaggggca ttgaaaatct gacccagctg aacgaacata
     1861 gccaaatgag tgtggagacg atccggaaaa tgccgaccaa tcacattatt attctggcga
     1921 aaaacgacat tggccggatt aatttatacc gtcttgtgtc agactccaac ctgatttact
     1981 atgccaagag gccgagaatt cccaaaagcg aaatcatgaa atacagagaa ggcctgatta
     2041 tcggctctgc ctgcgaggcg ggagagcttt accaggctct tttaagaggc gtgccggagg
     2101 cggagattaa caaaattgcc gaattttacg actatctgga gatccagcct ctgggaaaca
     2161 acggcttcat gctgcgggat gaaaagagcg ttgtcaaatc ggaggaggat ttaaaggatc
     2221 tgaaccggaa gattgtagag ctgggagagc ggtttaacaa accggtctgc gccacctgcg
     2281 acgtgcattt tctggatccg gaggacgagg tttacaggcg gattatcatg gcaggaaagg
     2341 gctttaagga ctgcgacgat cagcctcctc tctatttccg cacgacagag gaaatgctcc
     2401 gcgagtttga gtacctggga agcgacaagg cggaggaggt cgtgatcacc aacaccagac
     2461 ggattgccgc catgtgcgag cggattgccc ctgtccggcc tgacaagtgt ccgccggtca
     2521 ttccaaattc cgacgagatg ctgagaaaca tctgctataa cagagcccac gaaatgtatg
     2581 gagaaaatct tccgaaaatc gtagtggagc gtctggagag agagttaaac tccatcatct
     2641 ccaacggctt tgcggtgatg tatattattg cccagaagct ggtgtggaaa tccaacgagg
     2701 acggttatct ggtaggttcc cgtggttccg tcggttcctc ctttgtggcc accatgtcgg
     2761 gaattacgga ggtcaatccg ttaagtcccc actattactg tacggagtgc cattactatg
     2821 atttcgactc ggaggaggtt aagaagttct ccggtatggc gggctgcgat atgccggatc
     2881 gcctgtgtcc tgtctgcgga aagccgctga aaaaggacgg ctttgatatt ccgtttgaga
     2941 ccttcctggg ctttaaggga gacaaggagc ctgatatcga cttaaacttc tcaggagagt
     3001 atcagagccg ggctcacgac tacacggagg tcattttcgg caaagggcag accttccggg
     3061 ccggaaccat cggtactctg gcagataaga cggccttcgg atatgtgaaa aaatactatg
     3121 aggagagggg agagcgcaag cggggctgcg agatcaaccg gattgtcaca ggctgcgtcg
     3181 gcgtcaggag aacgaccgga cagcatccgg gaggcattat cgtgctgccc cacggggagg
     3241 agatctattc ctttaccccg gtgcagcacc cggcggacga tatgggaacg aagactatta
     3301 ccacccattt cgattaccac tccattgacc acaacttgct gaagctggat attctgggac
     3361 acgatgatcc caccatgatt cgtatgctgc aggatttgac aggccttgat ccggtcaggg
     3421 atattcctct tgactccaag gaggttatga gtctgttcca gagtaccgag gcccttggca
     3481 ttacgccgga cgatatcggc ggctgtccgc tgggggcgct gggcgtgccg gagttcggta
     3541 cggactttgc catgcagatg cttttagaca ccaagcctaa atatttctcg gatctggtcc
     3601 gcattgccgg actggcccac ggcacggacg tatggctggg aaatgcccag actctgattc
     3661 aggaggggaa agctaccatt cagacggcga tctgtaccag agacgacatc atggtctacc
     3721 tgatcggtat gggactggag gagggacttt ccttcaccat catggagagc gtccgaaaag
     3781 gcaaggggct gaaaccggag tgggaggagg agatgacggc ccacggggtg ccggactggt
     3841 atatctggtc ctgcaaaaaa atcaagtaca tgttccccaa ggcccacgcg gccgcctacg
     3901 ttatgatggc gtggcgaatc gcctactgca aggtcttcta tcccctcgcc tactacgcgg
     3961 cctttttcag catccgcgcc agcggctttt cctatgagct gatgtgccag gggcgagaaa
     4021 agctggaaca ccatctggcc gactacagaa agcggctgga cagcctctcc aaaaaagagc
     4081 aggatacgct gcgggatatg agaattgtcc aggaaatgta cgccagggga tatgaattta
     4141 cgcctattga catttataag gccagcgcga gaaatttcca gattatagac ggaaagctga
     4201 tgccttcctt aagcagtatc gacggactgg gggagaaagc ggcggacggt attgtatttg
     4261 ccgctgagga cggtccgttc ctgtccaagg aagattttat caaccgttcc aaagtgacga
     4321 aaacagtggc ggatctgatg gcagatctgg ggctgctgcg gggactgccg gagagcaacc
     4381 agctgtcgct gtttgatctg gcgctgtaaa aaacaagggg gaaaaccata tgaaatacga
     4441 ttttgagacg gttctggacc ggtatgacaa cggatctgta aaatggaatc tgatgaaaaa
     4501 gaaaaagccg caggtgggaa ggggcgtggt ccccttttcc atcgcggata tggaattcaa
     4561 aaatccgccg gaaattatcg aggcgttaaa ggaatatctg gatactgcgg tgctgggata
     4621 tcagacggca gagccgtcct ggtatgaggc tgtaaccgga tggacgaagc gcagatatgg
     4681 atgggagaca agaccggagt ggttttatac gactcccggg gtggtgaacg ccctctacca
     4741 cggcgttctg gccttcacag agccggaaga cggcgtgatt gtcatgccgc ctgtgtatta
     4801 tccattttac aaagcggtag agacaaatgg gagaagaacc gtcagatgtc cgctgaagga
     4861 aggaagggag ctttcctaca ccatagactt tgacaggctg gaagctctgg cctctgatcc
     4921 aaaaaatact cttctgattc tctgcaatcc ccataacccg gtgggacgcg tgtggaccag
     4981 acaggagctt ttaatggtca gccagatctg cctgcgccac cacgtgtttg tgatttctga
     5041 cgaaattcac tgcgacctga ttatgccagg gcacaccttt acttcctttg cctctctgtc
     5101 agaggaaaat gccgccaaca ctatgacctg cattgctccc agcaagacct tcaatctggc
     5161 cgggctggag gcttcctgcg tgattctgcc ggatcgggag agacgccatc agctgaaggc
     5221 agagatgagc cgcgtctcct acgaggggcg ggtaaacgcc ctgggatata aggccatgga
     5281 agccgcctac accaggtgcg accagtggct ttcacaggcg atccaggcca ttcacagcaa
     5341 tcatcgtctg ctgacagaat ttctgaaaga gcactgcccg gatgtaaagg ctgctccttt
     5401 ggagggaacg tatcttcagt ggctggatct gcgggctctc ggctggacac ctaaggagca
     5461 ggagagcatc atggaggagg cagatctgtt ttttgacgaa ggcggtatgt tcggtcctga
     5521 gggagaggga ttcgagcgga tgaatctggc ctgcccgcag acggttattc tggacggact
     5581 cggccgcttc agccaggtgg taaacaggcg aaagagagga ggcggggatg atcatagagg
     5641 ataatggttc cttaaatatg gcggatacac ttctcgttgt agatgatgta gaattaaaca
     5701 gggccattct cgcagaaata tttcaggatt cttaccagat tgaagaggca gaaaacggca
     5761 gggctgccct tgaaaagctg ataagcggca gagagcggtt ctgcggcgtg cttttggatg
     5821 tgatgatgcc tgaaatggat ggtatcagcc ttttaaaaat tctgcagggc tcgcatatga
     5881 cagaagaaat ccctgttttt ctcattacct ctgagacaag ccccgctctg tggaaggaag
     5941 cctattcttt aggcattatg gatctgattc ccaaaccagt cattccctat atcgtcaggt
     6001 acagagtcga ttccgttgtc aggctgttcc aggccaaaag aaggctgggc agccaggtgg
     6061 agcgccagaa ggacgagctt cttaaaaaag cggaggagat gtaccggctc agcattggca
     6121 tggcagaatc tctggccaat gtcattgaat ttaaaagcga cgaatccagc tcccacatca
     6181 ggaggatcca tgaaattacc atggctcttc tgcaggatac acgtctggga aacggccttt
     6241 ccaggcgcga tattgaacag atcggcctgg cggccatcat gcacgacgtg gggaaaattg
     6301 ccattccgga tcatatttta aataagcctg gacggttcac gccggatgaa tttgagttga
     6361 tgaaatccca caccttaaag ggcgtaacag gaaacctttc aatgaaacct ctttatcagc
     6421 ttacaagcag gcaggtagag cttttaagag ccggacagct tgaggaagcc agagagctga
     6481 tggcagacat tgacagagct tatgaagaga cagccggggc cctgaaggag taaatacatg
     6541 gttagacaga acagtgcaga cagaaaagga atacgccatg gaaaaaagca gagaaggatc
     6601 agagaaactc tgctgcggat aaggaagagc ctggttctgc tggttctgtt cgcggcaatt
     6661 tctaccgtaa gctttcatgt gatacagaat aacctgttag atcatgccag agtgatggga
     6721 gacggtcttg ccctttctta ctcagtggag gaagaaaaga atattacagc atatcaggtg
     6781 ctgatgaata tggagaccaa ttacctggat cagtttttag aatcaaagcc aagcgaggag
     6841 gagttaaagg cctggctgtc catcttttac aaaaataccg gagaggccct cggtaaaaat
     6901 tcgattcttc cctacgcggt aatcaatggg gccattattc cagccatcga gg
//
LOCUS       DBMDUW010000084         6937 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_4617_length_6937_cov_4.268432, whole genome shotgun sequence.
ACCESSION   DBMDUW010000084 DBMDUW010000000
VERSION     DBMDUW010000084.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 6937)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 6937)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6937
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4617_length_6937_cov_4.268432"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..240
                     /locus_tag="ACZPCR_11375"
     CDS             <1..240
                     /locus_tag="ACZPCR_11375"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231497.1"
                     /translation="RYNGISAGDGIKIREQMFVRFCTFKPVCDILRCNARDAFRTVYS
                     CFFHIELQRHTELPKKQIVNKIRQGLILQKFDEIP"
     gene            317..2317
                     /gene="uvrB"
                     /locus_tag="ACZPCR_11380"
     CDS             317..2317
                     /gene="uvrB"
                     /locus_tag="ACZPCR_11380"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HIR1231498.1"
                     /translation="MQNEQKIFKLHSEYQPTGDQPQAIEQLVQGFKEGNQFQTLLGVT
                     GSGKTFTMANVIAELNKPTLVIAHNKTLAAQLYGEFKEYFPSNAVEYFVSYYDYYQPE
                     AYVPSTDTYIEKDSSINDEIDKLRHSATAALSERSDVIIVASVSCIYGLGSPIDYKEM
                     VISLRPGMIKDRDEVIHKLIDIQYTRNDMDFKRGSFRVRGDVLEIYPAYSGGDAYRVE
                     FFEDEVDRITEIDTLTGEIKAQLGHIAIFPASHYVIPKEKMELAAQNILEELKEQTAW
                     FKSEDKLLEAQRISERTNFDVEMMRETGFCSGIENYSRHLTGSAPGEPPCTLIDYFPD
                     DFLIIVDESHITLPQIRGMYAGDRSRKKTLVEYGFRLPSALDNRPLNFEEFEQKIDQM
                     LFVSATPSDYEAAHEMLRAEQIIRPTGLLDPPIEVRPVEGQIDDLIGEVNREVEKKGK
                     VLITTLTKRMAEDLTDYMREVGIRVKYLHSDIDTLERAEIIRDMRLDVFDVLVGINLL
                     REGLDIPEISLVAILDADKEGFLRSETSLIQTVGRAARNAEGHVLMYADSITDSMAAA
                     IEETKRRRKIQQAYNEEHNITPTTIKKAVRDLISISQAAESAAADRVKDPESMDEREL
                     KQLAKELTKKMHQAAAELNFEEAASLRDQMIEIKKLLLEMEE"
     gene            2326..2613
                     /locus_tag="ACZPCR_11385"
     CDS             2326..2613
                     /locus_tag="ACZPCR_11385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006782096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046914 - transition metal ion binding
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FeoA family protein"
                     /protein_id="HIR1231499.1"
                     /translation="MRLYEGEAGSVYMVEAVVQKKLGEEWTRRLKSLGVVKGTRLLLL
                     TKKKGGTAAVKIRGTRLALGRKLAEAIEILPLEEPAAEWKERRRQTVEESE"
     gene            2597..4462
                     /gene="feoB"
                     /locus_tag="ACZPCR_11390"
     CDS             2597..4462
                     /gene="feoB"
                     /locus_tag="ACZPCR_11390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HIR1231500.1"
                     /translation="MKSPNESRILTVGLVGNPNCGKTTLFNALTGFQLKTANWPGVTV
                     EKASGWLSFEGIQIHLIDLPGIYSLDCSSAEEREAWKWLQAGGADVIINVADSGLLER
                     SLALTLQLMELKTPMVLALNAFDRKALKTGGQVSGWKLEQLQNCLGVPCLPISARKET
                     GLRELLKETAAAADGRSGGQDARTSSAFRCRNDEERYRYIEEIRFKCHEKTEHAINRT
                     DQADRWLMHPTWGIPIFLFLMAFVFFLTFSVGNIPKRGVEQLLECVLAAADSILNRTG
                     TARWLKSLILDGIIPGVGSVLSFLPNMIILFFALSVLEDSGYMARAAYVMNETMRMAG
                     LSGKSFLPLMLGFGCTVPAVTAARIVDGEPERKRTILAAHFMSCPARMTVYVLFSQMF
                     FPEHAVLAASSLYLAGMGAAVLTAVLHWKISGENREDCFLIELPEYRLPCAKHTIFCV
                     REKTEEYLAKAGTTIVLSSVLLWFLLHTGFSGFVSDISCSFAASAGRLLAPLFSLAGL
                     GDWQTAVALLSGLSAKEAVVSSFSVLYGIQNVNSEGGMAWLYSSLSASGFGPVNAYAL
                     MVFCLLYTPCSAAVSAVRTETGDGKWTACMAVFQLALAFLAASAVYQTGCLLFPG"
     gene            4547..5323
                     /locus_tag="ACZPCR_11395"
     CDS             4547..5323
                     /locus_tag="ACZPCR_11395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HIR1231501.1"
                     /translation="MRDRTLVDMAAQAGEIMLVSGAEIYRVEDTVARILRASGASGAE
                     VVVMATGIFITLTSGEGEPLSVVRRVRGRSTNMNRICRVNDVSRNFCTGILSVEEAKD
                     ALQEIGRELQYSRKLRILGYTVTPAAFAVIFDGGILEIAAAAMVGMVMALFEILINRV
                     KLNDFCSTAAEAFLAGILSLVLRAVLLPACSLNADAVIISALMPIVPGVIFTSAIRDT
                     LNGDYASGIARILEAIVVALAVASGVGAAMMLGGMLGGAL"
     gene            5323..5748
                     /locus_tag="ACZPCR_11400"
     CDS             5323..5748
                     /locus_tag="ACZPCR_11400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HIR1231502.1"
                     /translation="MEIIWQTIAAFIAIVGFGLLLEVPQKHIIHAGIAGAVCWLSYLT
                     VLEMGYSLIAAAFWSSIFVALLSHSFARMFKAPVTVFLVSGILPTVPGASIYRSVYYL
                     IQGASSLSNVYFMETLQISGAMAMAIFIVDSIFRLMQKR"
     gene            complement(5708..6676)
                     /locus_tag="ACZPCR_11405"
     CDS             complement(5708..6676)
                     /locus_tag="ACZPCR_11405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008395388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5688 family protein"
                     /protein_id="HIR1231503.1"
                     /translation="MTYETFLSLILNETQNLAGKDVSVSVQKTVKNNGVFLDSLSIRK
                     AGSSIAPAICLDPYYEEAESGTPMEAIARQILELAAQQSMFPPRLDSWLRDFSQVKTQ
                     IAFRLVSARENETLLSSVPHVPFLDLALIFYVIVEQQRDGQTTLLIHHEHAKLWNTDA
                     GGLYQLACSNTPLLLPAKITPLEQIIASLSPDIPMFQTDEITPAGLNQEEGAFPLHVL
                     TNSAGLNGAACILYPRILKNFAELVKDDVYILPSSIHEVLLTPVSSSPSVQELNQIVS
                     EINELDVPAEDRLSNHIYCYSPLEDQIFIPSCPSSASASSGIWNPQ"
BASE COUNT         1749 a         1505 c         2011 g         1672 t
ORIGIN      
        1 agatataacg gaatttctgc cggagacggc ataaagataa gagaacaaat gtttgttcgc
       61 ttctgtactt ttaaacccgt ttgtgatata ctaaggtgca atgccagaga tgcttttcgt
      121 accgtttatt cctgtttttt ccatatagaa ttacagaggc atactgagtt gccaaaaaag
      181 caaattgtga acaaaattcg tcaagggctt attttgcaaa aatttgatga aattccttga
      241 cgaaaatgaa aagttccttg acgaatttgt ggcatatagg cgtctttttt tactatgaaa
      301 tcggaggtga gtatttgtgc aaaatgaaca aaaaatcttc aaactccact cagaatacca
      361 gcccaccggc gaccagcccc aggccatcga acaactggtg caggggttca aagaaggcaa
      421 tcaattccag actttactgg gtgttacggg ttccggaaag accttcacca tggccaacgt
      481 gattgctgag cttaacaagc cgactttggt aatagcgcac aataagacgt tagctgcaca
      541 gctctatggc gagtttaaag agtactttcc gagtaacgca gtggagtatt ttgtctccta
      601 ttacgattat tatcagccgg aggcatatgt gccgtctaca gacacatata ttgaaaagga
      661 ttcatccatc aatgatgaga tcgataagct gcgccactct gccacagcgg ccctttcaga
      721 gcgcagcgat gtgattatcg tggcttctgt atcctgcatt tatggactgg gaagccccat
      781 tgactataag gagatggtga tttctctccg gcccggcatg atcaaggaca gggacgaggt
      841 gatccataag ctgattgaca ttcagtatac gagaaatgat atggatttta agcgcggaag
      901 cttccgcgtc aggggagacg tgctggagat ttatcccgcc tattccggcg gggacgccta
      961 ccgggtggag ttttttgagg acgaggtgga tcggattacg gagattgaca ccctgaccgg
     1021 ggagattaag gcccagctgg gtcatatcgc catttttccg gcctcccact atgtgattcc
     1081 caaggagaaa atggagctgg cggctcagaa tattctggag gagctgaagg agcagacagc
     1141 ctggtttaaa agcgaggata agcttctgga ggcccagaga atctcagaga gaactaattt
     1201 tgacgtggag atgatgcgtg agacgggatt ttgctctgga attgagaact attcccgtca
     1261 tctgaccgga tcggcgcctg gggaaccgcc ctgtacgctg atcgactatt ttccggacga
     1321 ttttctgatt attgtagacg agtcccacat tacactgccc cagatccggg gaatgtacgc
     1381 gggagatcgt tccaggaaga agactctggt agagtacggc ttccgcctgc cctctgcgct
     1441 tgacaaccgt cctctgaatt ttgaggagtt tgagcagaag attgaccaga tgctctttgt
     1501 atcggccacg ccgtccgact acgaggcggc ccatgaaatg ctgcgggcag agcagattat
     1561 ccgcccgaca ggactcttag atccgcctat cgaggtgcgc ccggtggaag gccagattga
     1621 cgatctgatc ggggaggtca accgcgaagt ggagaagaag ggaaaggtgc tgattaccac
     1681 tctgacgaag cggatggcag aggatctgac agactacatg agggaggttg ggatccgcgt
     1741 aaaatacctt cactcagata tcgacactct ggaaagggct gagattatca gggatatgcg
     1801 tcttgacgtg ttcgacgtgc tggtaggcat taaccttttg agggagggac ttgacattcc
     1861 ggagatttct ctggtggcaa ttctcgacgc agacaaggaa ggcttcctcc gctcggagac
     1921 gtcgctgatc cagaccgtgg gaagagctgc cagaaacgcg gagggccatg tgttgatgta
     1981 cgcggacagc attaccgatt ccatggcggc ggccatcgag gagacaaaga gaagacggaa
     2041 aattcagcag gcctacaatg aggagcacaa cattacgcct acgacgatca agaaggcagt
     2101 ccgggacctg atcagtattt cccaggcagc ggaaagcgcc gcagcagaca gagtgaagga
     2161 tccggagtct atggacgaac gggaattaaa gcagctggcg aaggagttga caaagaagat
     2221 gcatcaggcc gccgcggagc tgaactttga ggaggctgct tccttgcggg atcagatgat
     2281 agagattaag aagcttctgt tagagatgga ggaataaaag ccgctatgag actgtatgag
     2341 ggggaagcgg ggagcgtcta tatggtagag gcagtcgttc agaagaaact gggagaggag
     2401 tggaccaggc gtctgaaatc tctgggagtg gtgaagggca caaggcttct gctcctgacg
     2461 aaaaagaaag gcggaacggc ggcagtcaaa atcaggggaa cccgtctggc tcttggaaga
     2521 aaactggcgg aagccattga gattctccct ctggaagagc cggcggcaga atggaaggaa
     2581 agaaggaggc agacggttga agagtccgaa tgaaagcaga atactgactg tggggctggt
     2641 cggaaatcca aactgcggga agacgacgtt atttaacgcg ctgacgggtt ttcagctgaa
     2701 aactgccaac tggccgggcg tgacagtgga gaaggcgtcc ggctggcttt catttgaagg
     2761 aattcagatt catctgatag atctgcctgg aatttacagt ctggactgca gcagcgcaga
     2821 ggagagagag gcctggaagt ggcttcaggc cggcggggca gacgtgatta tcaatgtggc
     2881 ggacagcggc cttctggaaa ggagtcttgc tctgacgctt cagctgatgg agctgaaaac
     2941 gcctatggtg ctggctttga atgcgtttga caggaaagcg ttaaagacag gaggccaggt
     3001 ttccggatgg aagctggaac agctgcaaaa ttgcctggga gtcccctgcc tgcctatatc
     3061 tgccagaaag gagacaggcc ttcgcgagct tttaaaagag actgccgcag cggcagacgg
     3121 gcgttccggc gggcaggacg ccaggacgtc ttctgcattt cggtgcagaa acgatgaaga
     3181 gagatatcga tatatagaag aaatacgttt taaatgccat gagaaaacag aacacgccat
     3241 caaccggacg gatcaggctg atcggtggct gatgcatccc acctggggaa tccctatttt
     3301 tctgtttctg atggcatttg tcttttttct taccttttca gtaggaaata ttcccaagcg
     3361 gggggtggag cagcttttag aatgcgtcct ggcggcagcg gattccattc tgaataggac
     3421 cggaacggcg agatggctga aatcgctgat tctggacgga atcattccgg gcgtgggaag
     3481 cgtactcagc tttcttccca acatgatcat tctgttcttt gcgctgtctg ttctggagga
     3541 cagcgggtat atggccagag ccgcctatgt gatgaacgaa acgatgagaa tggcgggact
     3601 gtcaggaaaa tcctttctgc ctctgatgct gggctttggc tgcacagttc cggctgtgac
     3661 agccgccaga attgtggacg gagaacctga aagaaagcgc acgattctgg ccgcccattt
     3721 tatgtcatgc ccggccagaa tgaccgtgta cgttttgttt tcccagatgt tttttcctga
     3781 acatgccgtt ttagcggcca gctccctgta cctggcggga atgggggcgg ctgtgttaac
     3841 tgcagttctc cactggaaga tatcggggga gaacagggag gactgttttt tgatagagct
     3901 cccagagtac agactgcctt gtgcaaagca cacgatattc tgcgtgaggg aaaagacaga
     3961 ggagtacctt gcgaaggcag ggacaacgat tgttttatct tccgtgcttc tctggttcct
     4021 tcttcacacc ggcttctccg gctttgtatc tgatatctcc tgcagcttcg cggcgtcagc
     4081 cggccgtttg cttgcgcctc ttttttccct ggccggtctg ggagactggc agacagccgt
     4141 cgccctgctg tcggggcttt ctgccaagga ggccgtagtg tccagttttt cagttcttta
     4201 cggaattcag aacgtcaatt cggaaggcgg catggcatgg ctttattcaa gcctttctgc
     4261 ttctggcttt ggacctgtaa acgcctatgc cctgatggta ttctgccttc tttacacgcc
     4321 ctgctccgcg gctgtgtctg cggtgaggac agaaacggga gatgggaaat ggactgcctg
     4381 catggcggta tttcagctgg cgcttgcatt tctggcggcg tcagctgtgt accagactgg
     4441 ctgcctgctg tttcctggat agaggaatca ggaaagacgc gccaaacagt tgacattttt
     4501 tctgtacatg atataattca gggacatttc aaaaggagcg tcaaagatga gagacagaac
     4561 attggtggat atggctgccc aggctggtga gatcatgctg gtcagcggag ctgagattta
     4621 ccgtgtagaa gacactgtcg cccggattct cagggcgtca ggtgcttccg gggcggaggt
     4681 ggttgtgatg gccacaggta tttttattac gctgacgtcg ggggagggag aacctctcag
     4741 cgtagtgcgc agagtcaggg gacggtcgac gaacatgaat cgaatctgca gggtaaacga
     4801 cgtatcaaga aacttctgta ccggtattct ctctgtggag gaggcaaagg acgccctgca
     4861 ggagataggg agggagcttc agtacagccg aaaactgaga atcctgggat ataccgttac
     4921 tccggctgcc tttgccgtaa tatttgacgg cggcattctg gaaatagcgg cggcagctat
     4981 ggtgggcatg gtgatggcct tgtttgagat tctgatcaac cgggtgaagc tgaacgattt
     5041 ctgctctact gcagcagaag cctttttggc cggcatcctg tctctggttt taagagctgt
     5101 tctgcttcct gcctgcagcc tgaatgcaga cgcggtgatt atcagcgccc tgatgcctat
     5161 cgttcccggc gttattttta cctcggccat cagagatacg ctgaacggag attacgcttc
     5221 cggaatcgcc aggatattag aggcgattgt ggtggctctg gcggtggcgt caggagtcgg
     5281 agcggccatg atgctgggcg gcatgctggg aggtgcgttg tgatggagat tatttggcag
     5341 acaatcgctg cgtttattgc tattgtgggc tttggactgc ttctggaggt tccccagaag
     5401 cacattatcc atgcgggaat cgcaggggcg gtgtgctggc tgtcctacct gactgtactg
     5461 gagatgggat attcgctgat agcggcggct ttctggtcca gcatctttgt ggccctttta
     5521 agccacagct ttgccagaat gttcaaagct cctgtgactg tttttctggt atcgggaatt
     5581 ctgcccacgg tgccgggcgc ttctatttac agaagcgttt actatctgat tcagggagcc
     5641 tcctctcttt caaacgtcta ttttatggag acgctgcaga tttccggcgc tatggccatg
     5701 gctattttta ttgtggattc catattccgc ttgatgcaga agcgctagaa gggcaggagg
     5761 gaataaaaat ctgatcctcc agaggactgt agcagtaaat atgattggac aggcgatcct
     5821 ccgcagggac gtccagttca ttgatctcag agacaatctg attcagctcc tggacagagg
     5881 gagaagagga gacgggagtt aacaaaactt cgtggatgct tgagggaagg atatatacgt
     5941 catccttcac aagctctgcg aagtttttta agatccgggg atagagaatg caggcggcgc
     6001 cgttcaggcc ggcagaattg gtgagaacat ggagcggaaa ggcgccttcc tcctgattta
     6061 agccggctgg ggtaatttca tcggtctgaa acatagggat atcgggagaa agagaggcaa
     6121 tgatctgctc taacggcgtg atcttagcgg gcagcagaag gggcgtattg gaacaggcca
     6181 gctgataaag cccgccggcg tcggtattcc acagctttgc gtgctcatgg tgaatcagga
     6241 gcgttgtctg gccgtccctc tgctgttcta caatgacata aaaaatcagg gccagatcga
     6301 gaaatggaac gtggggaacg gacgacagaa gggtttcatt ttccctggca gagacaaggc
     6361 ggaaggctat ctgtgtttta acctgggaaa agtcgcggag ccaggaatcc agtctgggcg
     6421 gaaacatgct ctgctgagct gccagctcca gaatctgccg ggcaattgcc tccataggag
     6481 tgccagactc agcttcctca tagtaaggat ccaggcagat ggccggagcg atggaggaac
     6541 cggcttttcg tatcgacaga ctgtccagga aaacgccgtt atttttgaca gttttctgga
     6601 cagatacaga aacgtccttt cctgccaggt tttgagtttc gttgagaatc agtgatagaa
     6661 atgtttcgta ggtcatatgt gcctccttta gtagaatata agaattgtga aatatgaaaa
     6721 tcatagacag caaggtatgc tgaaagaata gatgcagtct attatataga aatagagaag
     6781 tattttcaat taaaaaagta taaaataaca gaacaaaagc cactatttat gtgagattat
     6841 aagcgcataa aagaatataa gtcagaaatt atagaaaaat aataaaaata gtgttgacaa
     6901 aatggaagca ttaagctata ataaagacaa caaaaca
//
LOCUS       DBMDUW010000085         6856 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_4681_length_6856_cov_3.622946, whole genome shotgun sequence.
ACCESSION   DBMDUW010000085 DBMDUW010000000
VERSION     DBMDUW010000085.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 6856)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 6856)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6856
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4681_length_6856_cov_3.622946"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(1..72)
                     /locus_tag="ACZPCR_11410"
     tRNA            complement(1..72)
                     /locus_tag="ACZPCR_11410"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(37..39),aa:Glu,seq:ctc)
     gene            complement(287..2818)
                     /locus_tag="ACZPCR_11415"
     CDS             complement(287..2818)
                     /locus_tag="ACZPCR_11415"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008976141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0140358 - P-type transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HIR1231504.1"
                     /translation="MKQYVVTGMSCAACSARVEKAVSKVEGVTSCSVSLLTNSMGVEG
                     TAQPEDIIAAVEAAGYGASVKDGSGQKKDSAAGSAEEDMLADRETPVLKRRLTASLAF
                     LIVLMYVSMGHMMWGWPLPEVLAENHVAVGLVQLLLTGIVMVINQKFFINGFKSLWNK
                     APNMDTLVALGSGASFLYSVYALFAMTDAQMRGDMAGVMEYMHEFYFESVAMILTLIT
                     VGKMLEARSKGKTTDALKNLMKMTPKTAVVWRNGEETEISIDQVAEGDIFLVRPGGNI
                     PVDGVILEGTSAVDESALTGESIPVDKAAGDKVFAATLNQSGFIRCQASRVGEDTTFS
                     QIIQMVSDAAATKAPIAKAADRVSGIFVPAVIGISLVTAVGWMIAGQSFGFALARGIS
                     VLVISCPCALGLATPVAIMVGNGVGAKNGILFKTAAALEEAGRTEIIALDKTGTITMG
                     EPHVTDLLPAPGVTEDQLLSLAAALEKKSEHPLARSVMRKAEELGLEPEEAEEFEALV
                     GSGVSASLKGRKLLGGSLSFMSGRIEVPETARKQAESFAEQGKTPLLFAEDETFAGVI
                     AVADVIKEDSPQAVRELQRMGICVVMLTGDNEKTAQAIGRQAGVDEVIAGVLPDGKEA
                     VIRALKEKGKTAMVGDGINDAPALTRADLGIAIGAGTDVAIDAADVVLMKSRLSDVPA
                     AIRLSRGTLRNIHENLFWAFFYNAVGIPLAAGLFIPLLGWKLNPMFGAAAMSLSSFCV
                     VSNALRLNFLSIRDGSRDKKIKTKHHELEKESQKMEKTMNIEGMMCGHCEARIKKTLE
                     AIPGVEAAEVSHEKGTAVVKMASEVADEVLKKAVEDQDYQVTGIQ"
     gene            complement(2904..3719)
                     /gene="thiD"
                     /locus_tag="ACZPCR_11420"
     CDS             complement(2904..3719)
                     /gene="thiD"
                     /locus_tag="ACZPCR_11420"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009203319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HIR1231505.1"
                     /translation="MKTVLTIAGSDSSGGAGIQADLKTMIMNGVFGMSAVTALTAQNT
                     IGVSGILAVDGDFLRRQIDAVFEDIRPDAVKIGMAVSKELIQVAAERLLFYRADHVVV
                     DPVMISTSGSRLLQPDAVEELTRRLFPLAQLVTPNIPEAELLSGRTIADRNDMELAAE
                     HIGKAYGCAVLLKGGHSVQDADDLLYADGRTEWFAGKRIDTSNTHGTGCTLSSAIASN
                     LAKGFSLRESVKRSKEYLSGALSARMNLGAGSGPVDHGFCLNGYFSESAVLPV"
     gene            complement(3716..4027)
                     /locus_tag="ACZPCR_11425"
     CDS             complement(3716..4027)
                     /locus_tag="ACZPCR_11425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007592285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HIR1231506.1"
                     /translation="MSASIGIQVLPQVGSDEEVCRIVDEVIACIKSTGLRYEVGPLET
                     VIEGESFDQLMELAAECQKTAVRAGAPKVISYIKVIYKPEGEILTIDQKIGKYREEGN
                     Q"
     gene            complement(4024..4680)
                     /locus_tag="ACZPCR_11430"
     CDS             complement(4024..4680)
                     /locus_tag="ACZPCR_11430"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008395071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HIR1231507.1"
                     /translation="MNKKYAIFDLDGTLIDSMRWWKGLAEEFLRSRGVTEIPDGLTDQ
                     IQTMTVLESSRLFIRTFGISGTAESVAGEMNALMDRHYREDISLKPGVKACLDTLKKK
                     GVRMCVASAASAKLAEDCLKRLGTADYFEEFLSCEDVGAGKTRPDIYLRAAAGMGAAP
                     EDTAVYEDALYAAETAKKAGFYVIGVYDEGSCRTKEERKRLGDLADEMIECWEEEEKL
                     "
     gene            complement(4673..5332)
                     /gene="thiE"
                     /locus_tag="ACZPCR_11435"
     CDS             complement(4673..5332)
                     /gene="thiE"
                     /locus_tag="ACZPCR_11435"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HIR1231508.1"
                     /translation="MKFSKEQIRQAMLLYGITDRSWLKPGEKLSDVCREILEHGVTFL
                     QLREKELDQEAFLKEAEELKELCARFGVPFVVNDSVETAVQAGADGVHVGQSDIKGRN
                     IRAMIGPDRILGISAGTVEEARAAEKAGADYIGVGAVFGTSTKKDARNLSVEKLREIS
                     ASVSIPVVAIGGINRSNVGELSGSDVDGIAVISALFGAERPGEAAAELAELAKEIRDS
                     E"
     gene            complement(5319..6188)
                     /gene="thiM"
                     /locus_tag="ACZPCR_11440"
     CDS             complement(5319..6188)
                     /gene="thiM"
                     /locus_tag="ACZPCR_11440"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HIR1231509.1"
                     /translation="MEYGGKKEGAVMEDLTKRAWEIFRQVQEKRPLVQCITNFVTVND
                     CANMILAAGGSPSMAHDIREAAEAAAAASALVCNLGAIGDTDAMEAAGKAANLLGIPV
                     VFDPVAAGGTSLRRAEAARLMRAVHFSVIRGNASEIRFLAGEQSSGSGVDAGMFDEIT
                     EENLSAAIGIVKGLAEKTGSVIAVSGRLDLISDSRRTAVLRNGSPVMARITGSGCMLT
                     ALTGAFCGACQKDCFTAAFAASAVMGVCGELADAKRLERGTGNASFRNDLIDAVFTLT
                     EKQFREEINYEIF"
     gene            complement(6240..6770)
                     /gene="thiW"
                     /locus_tag="ACZPCR_11445"
     CDS             complement(6240..6770)
                     /gene="thiW"
                     /locus_tag="ACZPCR_11445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003508447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HIR1231510.1"
                     /translation="MNQHQTVKTETGAKSRTLKLVMTGMLACLAFVLNTFVYFPSMAP
                     FQHFVDVLAAVFLGPWYGCASAFLCGIMRMMSGRTIQAVTGAVFGPVLGGFLYRKTKN
                     IYLVFVGEVIGTGFLGAMASYPLMKLFYGLDAQSPFYYIPFYTPSAVTGAAMGLAVLL
                     MLKKGRLLERMERELE"
BASE COUNT         1467 a         2216 c         1469 g         1704 t
ORIGIN      
        1 tgacctgtcc gggaatcgaa cccgggttta cgccgtgaga gggcgtcgtc ttgaccgctt
       61 gaccaacagg ccttctattt tgtttttctg tcgctcgctg tcgacttaga tagtatatca
      121 tacttccgga aaaatgcaag cacttttttt aatttttttt aattttttca actttttgat
      181 ttctttttca tttcctcttg tttcatttca cacagcggag ctggccgcgt atcctcctgt
      241 cccataaacg ggcaaagagg ggagaacgct cccccctctc ctctctctac tgaattccag
      301 tcacctggta atcctgatct tccacggcct tcttcagcac ctcatccgct acctctgatg
      361 ccatcttcac tacggcagtc cctttctcat ggctgacctc cgctgcctcc actcccggaa
      421 tagcctccag agtcttctta attctggcct cgcagtgtcc gcacatcatt ccctcgatgt
      481 tcattgtctt ttccatcttt tgactctcct tttctaattc atgatgtttt gtttttattt
      541 ttttatccct cgatccatct ctgatggaaa ggaagtttaa acgaagcgca ttggatacca
      601 cgcagaagct ggaaaggctc atagcggcgg ctccaaacat gggatttaat ttccatccca
      661 gcagaggaat gaaaagccct gctgccagtg gaattcccac tgcattgtag aaaaatgccc
      721 agaacaggtt ttcgtggata ttcctcaaag ttccccggct gagacggatg gccgccggca
      781 cgtcgctcaa ccggcttttc atcagaacta cgtccgccgc gtcgatagcc acgtctgtcc
      841 ccgctccgat ggcgattccc agatccgctc tcgtcagagc cggcgcatcg ttaatgccgt
      901 ctcccaccat agccgttttt cccttttcct tcagggcgcg gattacagcc tcctttccgt
      961 ccggaagcac tcctgcaatc acctcgtcca cgccagcctg ccttccaatg gcctgagccg
     1021 tcttttcatt gtccccggtc agcataacca cgcagatacc catacgttgg agttccctca
     1081 cagcctgagg gctgtcctcc ttgatcacgt ctgccaccgc aatcacgcct gcaaacgtct
     1141 catcctccgc aaataaaagc ggcgttttgc cctgctccgc aaaagactct gcctgctttc
     1201 tcgctgtttc cgggacctca atccggccgc tcataaacga aagacttcct cccagaagct
     1261 ttctgccctt taatgaggcg gacacgccgc ttcccaccag ggcctcaaac tcctctgcct
     1321 cctccggttc cagtcccagt tcctccgctt tccgcatcac agacctggcc agagggtgct
     1381 cgcttttctt ttcaagggca gccgccagac ttaacagctg atcctctgtc actccgggag
     1441 caggcagcag atcggtcaca tggggctctc ccatagtgat ggttcccgtc ttatcgagag
     1501 cgataatctc tgtccttcca gcctcctcca gagcggcggc cgtcttaaac agaatcccgt
     1561 ttttcgctcc cacgccgtta cccaccataa tggctaccgg cgtggcaagt cctaacgcgc
     1621 aggggcagct gataacaagg acggaaattc cacgggccag tgcaaagcca aagctctgtc
     1681 ctgctatcat ccatcccaca gccgtcacaa gggaaattcc aataaccgcc ggcacgaaaa
     1741 tgcctgacac ccggtccgcc gccttggcga taggggcctt cgtggcagcc gcgtcgctga
     1801 ccatctggat aatctgggaa aaggtggtat cctcccccac tctggacgcc tggcagcgga
     1861 tgaagccgga ctggttcaga gtggccgcga acaccttgtc ccctgccgct ttatccacag
     1921 gaatgctctc tcccgtcagc gccgactcgt ccaccgcgct ggttccctcc aggatcactc
     1981 cgtccaccgg aatgtttccg cctgggcgga ccagaaaaat gtctccctct gccacctggt
     2041 caatggaaat ctccgtctcc tcgccgtttc gccacacgac agccgtcttc ggcgtcattt
     2101 tcatcagatt tttcagggcg tccgtagtct ttcccttgga gcgggcctct aacatttttc
     2161 cgacggtaat cagcgtcagg atcatggcta ccgactcaaa gtaaaactca tgcatgtatt
     2221 ccatgacccc agccatatcg ccccgcatct gggcgtccgt catggcaaac aaggcgtaca
     2281 cgctgtagag gaaggacgcg ccggagccca gagccaccag agtgtccata ttgggtgctt
     2341 tattccacag actcttaaag ccattgataa aaaatttctg gttaatcacc atgacaatgc
     2401 ctgtgagaag cagctgcaca agccctacag ccacatgatt ttcagcgaga acctccggaa
     2461 gaggccagcc ccacatcata tggcccatgg aaacgtacat aagcacaatc aaaaaagcca
     2521 gggaggctgt caggcgtctt ttcagaacgg gcgtttcccg atctgccagc atatcttcct
     2581 cagcgcttcc cgccgcactg tccttcttct gcccggatcc gtctttgaca gaagcgccgt
     2641 atcccgccgc ttccactgcc gcgataatat cttcaggctg agccgtgcct tccacgccca
     2701 tggaattagt cagaaggctg acagagcagg aggtaactcc ctccaccttt gacacagcct
     2761 tctctacccg ggcactgcag gccgcgcagc tcataccggt cacaacgtac tgtttcatct
     2821 atttacctcc ttttcctgat gctattatat accccatcag ggtattagtc aagaggcaga
     2881 taaaaaacag ggcgcggtac gcctcacacg ggaagaactg cgctttccga aaaatatccg
     2941 ttcaggcaga agccgtgatc tacagggccg cttcccgctc ccagattcat ccgggcagaa
     3001 agggcgccgg acagatattc cttggatctt ttcaccgatt ccctgaggga aaagcccttg
     3061 gccaggttgg aagcgatggc gcttgacagg gtgcagcccg ttccgtgggt attggatgtg
     3121 tcgatccgct ttccagcaaa ccactctgtc cttccgtctg catacagaag atcgtcggca
     3181 tcctggacgc tgtgtcctcc ctttaacagc accgcgcagc cgtacgcttt gccgatatgc
     3241 tccgccgcca gctccatgtc gtttctgtct gcaatggttc tccccgacag aagctccgcc
     3301 tcaggaatat tgggagtaac cagctgggcc aggggaaaca gcctgcgcgt aagctcttcc
     3361 acggcgtccg gctgaagcag cctggatcca ctggtggaaa tcataaccgg gtccactacc
     3421 acatgatccg ctctgtaaaa cagaaggcgc tctgcagcca cctggatcag ctctttggaa
     3481 acggccattc caatcttgac tgcgtccggg cggatgtcct caaacaccgc gtcaatctgc
     3541 cgtctcagaa agtctccgtc cactgccagg ataccagata cccctatcgt gttttgagct
     3601 gtcagggccg tgacggcgct cattccgaat acgccgttca taatcatggt ttttaagtct
     3661 gcctggattc cagctcctcc gctggagtcg cttcccgcaa tcgtcaatac cgttttcact
     3721 gattcccctc ctctctgtat tttccgattt tctgatcaat cgtcaaaatt tccccctccg
     3781 gcttataaat aaccttaata taggaaatca ctttcggcgc tccggcccgg actgccgttt
     3841 tctggcattc tgccgccagc tccatcagct ggtcaaagct ctctccttct atcaccgtct
     3901 ccaggggccc tacctcatag cgaaggcctg tgctcttaat acaggcaatc acttcgtcta
     3961 cgattctgca tacctcctcg tcgcttccca cctgcggaag cacctgaatt ccaatacttg
     4021 cgctcatagc ttttcctcct cttcccagca ttctatcatc tcgtccgcca aatctcccag
     4081 gcgtttccgt tcctcctttg ttctgcagct gccttcgtca tataccccta tcacataaaa
     4141 gcctgctttc tttgcagttt cagccgcata cagggcgtcc tcatagacag ccgtgtcctc
     4201 cggggccgcc cccattcccg ctgccgccct cagataaatg tcagggcgcg tcttgcctgc
     4261 gcccacgtcc tcgcaggaaa gaaattcctc aaaataatct gcagttccca gacgcttcag
     4321 acagtcctct gccagctttg ccgatgcggc ggaagccacg cacatcctga cgcctttctt
     4381 tttcagcgta tccaggcagg cttttactcc cggtttcaga gaaatatctt ctctgtaatg
     4441 gcgatccatc agggcgttca tttccccagc caccgattcc gctgtccctg aaattccaaa
     4501 cgtgcggata aacagtctgg aggattccag gaccgtcatc gtctgaatct gatctgtcag
     4561 accgtctgga atttctgtca ctcctctgct tcgcaaaaat tcttccgcca atcccttcca
     4621 ccatctcatg gaatcgatca gagtgccgtc taaatcgaaa atcgcatact ttttattcac
     4681 tgtctctgat ctcctttgcc agctctgcca attctgcagc cgcttctcct ggacgctccg
     4741 ctccaaaaag agccgatatg acagcgattc cgtctacatc actgcctgaa agctccccca
     4801 cgttggagcg gttaattcct ccaatggcaa ctaccgggat cgatacagaa gcagaaattt
     4861 cccgcagctt ctcaaccgaa aggtttctgg cgtctttttt cgtggaggtc ccaaacacag
     4921 ctcccacccc gatatagtcg gcccctgctt tttctgctgc tctggcctcc tccacagttc
     4981 cggcggaaat gcccagaatc cgatccggcc ctatcatggc cctgatattc cgccccttaa
     5041 tatctgactg tcccacatgg acgccgtcgg ccccggcctg aacagctgtc tccacgctgt
     5101 cgtttaccac aaacggaacg ccaaaccggg cgcacagctc ctttaactcc tccgcttcct
     5161 tcagaaatgc ctcctgatcc agctcctttt cccgaagctg gagaaaggtc actccatgtt
     5221 ctaaaatttc ccggcatacg tctgagagct tctcccctgg cttcagccag gagcggtccg
     5281 tgatcccata aagaagcatg gcctgcctga tctgttcctt agaaaatttc ataattaatt
     5341 tcctccctaa actgtttttc cgtcaaagta aagaccgcgt cgatcaaatc attgcgaaaa
     5401 gacgcgtttc ctgttccccg ttccagtctc ttcgcatccg ccagttcccc gcagactccc
     5461 ataacggcgg aggcggcaaa ggctgcggta aagcagtcct tctggcacgc cccgcagaaa
     5521 gcccccgtaa gagcggtcag catacaaccg cttcccgtga tacgcgccat cacgggactt
     5581 ccatttctca aaactgccgt ccgcctgctg tcagagatca gatcaagcct tcctgaaacg
     5641 gcaatcacgc tgcctgtttt ctctgccagc ccctttacta tcccgatagc ggcggacaga
     5701 ttctcctccg taatctcatc gaacattcct gcgtccacgc cgcttccaga tgactgttct
     5761 cctgccagaa aacggatctc cgacgcattt ccccggatca cagaaaaatg gacggctctc
     5821 ataagccttg ctgcctccgc ccggcgcagg ctggttcctc cggccgccac cgggtcgaat
     5881 accactggaa tccccagaag gttcgccgcc tttcccgcag cttccatagc gtccgtatct
     5941 cctatagccc ccagattgca gaccagcgcg gaggctgcag ctgccgcctc cgcagcctcc
     6001 ctgatatcgt gggccatgga gggagagcct ccggccgcca gaatcatatt ggcgcagtcg
     6061 ttgactgtga caaaattagt aatgcactgc actaaggggc gtttctcctg cacctgccta
     6121 aagatctccc atgcccgctt cgtcaaatcc tccataacag ctccttcctt ctttcctcca
     6181 tactccaatt ccgctttttt cttctgttcc gcttttcttt actctagttc tgctttcctt
     6241 tactccagtt ctctctccat ccgttccaac agtctgcctt ttttcagcat caaaagtacc
     6301 gccagcccca tagcggctcc cgtcaccgct gaaggtgtat aaaacggaat gtagtaaaaa
     6361 ggcgactggg cgtctaagcc gtaaaacagc ttcataagcg gataggaagc cattgctcct
     6421 aaaaagcccg ttccaatcac ctctcccaca aagaccagat aaatattttt tgtttttctg
     6481 tacaggaacc cgcccagcac agggccaaac acagcccctg tcactgcctg gatcgtccgg
     6541 cctgacatca tcctcataat accgcataaa aatgcgctgg cacacccata ccacggtccc
     6601 agaaagaccg cagccagcac atctacgaaa tgctggaatg gagccattga gggaaaatac
     6661 acaaaagtgt tcagcacaaa ggccagacag gccagcatgc ctgtcatcac cagtttaagc
     6721 gtcctgcttt ttgccccggt ttccgttttt actgtctgat gttgattcat aacgttctcc
     6781 ttttcccgga aaactctgtg gagtgcagat tcattaaaac acaaaaacgg agacgcctga
     6841 aaacgacgtc tccgaa
//
LOCUS       DBMDUW010000086         6663 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_4822_length_6663_cov_3.215635, whole genome shotgun sequence.
ACCESSION   DBMDUW010000086 DBMDUW010000000
VERSION     DBMDUW010000086.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 6663)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 6663)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6663
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4822_length_6663_cov_3.215635"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(276..3410)
                     /locus_tag="ACZPCR_11450"
     CDS             complement(276..3410)
                     /locus_tag="ACZPCR_11450"
                     /inference="COORDINATES: protein motif:HMM:NF016932.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="suppressor of fused domain protein"
                     /protein_id="HIR1231511.1"
                     /translation="MTLLEQCQRWNKNDEFQKIIDALEKIPAEERTPEEDSELARAYN
                     NLAQPGEKELFQKAIALLEPHEEYFAGDHSWNFRMGYAYYYLDQEGPALRYFEQALAA
                     RPGDEDTEELIEDCRSRLVLPRFDKNFRERTEEAWAAFAEIEKELRSIMDSDTMRERG
                     EELMEQCSTALELAFHFPAFELGFNGGKYELILSAEGVRSSLFPLVYFKRHAPEPVRE
                     HWNILVGRQPSKEFILRTGETEIQAEDVQTWARQEDGRIFLTLWCEKLIPLMREDESR
                     AWWILYTLVDQTLGEISSVALIGRLDITEQPPEEPSFLLSELPQTLLDMECSLWDDAE
                     SYLDSSYVGYEMKPVEDPEADWRFDVFSGSARLPVLINEYMSGESETADEYHMDGIAA
                     GFLYFPLEGFSGENRAEQILKFRDALQEAVRGQAGDDAADFLGGATGLYYGYLDFIAW
                     DLPAVLDAARDFFAGTELACGGFHVFRRGLGAVRLWEQEKEPQIDPETGSLLMAEDIE
                     NLEAFDDGISGYFGKMLQYLEDFVKRGVETGKFTERQARQDLQIALWYSFACSNLDEY
                     RYYYKAAQWMPDSEKNAKGCATWYYRYSVALTYCGRLEEALDYAEQGTKEEPDYPWIW
                     LQAGKLRAHFGDREGALEAAARGLLLEPGDYEFLTLKKEIEAGEPLERMEYHWINPGA
                     DQALQQGRDEDAENKRRSISCITVNQEGLERFWEIFGPKPKQYVPNAPYTQFPYTVKG
                     STIDLVFQMNEAGMSKLNADWLRQVKSWLSDGRWLERNHLDGRAAKLNAALVGLDCQI
                     GLFYQLCGAEEYFQIFLRPDGTKIEGSFWSSEEGRDTAFYTEEEMDVVERHISACFGT
                     IENVFHELVSPDIHVDVCMIPPEGERDYVTLVTMGMGARPMNVPGELAEYKLERAELA
                     IALPPDWKLDQESMKDEKWYWPVRLLKTLARLPITSDTWLGWGHTVDNKKPFAENTKL
                     CAAVLTEPKNIEENGFICQLPGDRPVNFYQVIPLYREELEYKIKQSAQELLEIMAEAG
                     FVAEPDRRNYAEEK"
     gene            complement(3464..4765)
                     /locus_tag="ACZPCR_11455"
     CDS             complement(3464..4765)
                     /locus_tag="ACZPCR_11455"
                     /inference="COORDINATES: protein motif:HMM:NF019284.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system YwqK family antitoxin"
                     /protein_id="HIR1231512.1"
                     /translation="MKYYMYAENQTVQTLREILEEEAQRNPMWTLQELFAMCRNLSFL
                     DDVPENADYFDEIYLIFAELFTEFNRYGQFDGGSWDLQNVRAFSADEESEKELISALD
                     ALYSGMIQGRKRVLTARWEKEGTWQEWRQHIGELRTETAAVWPTETGSGWTEETRTEE
                     PGNTKKSRGNRKKRAAVSAVVLAVLLSAAGWLAYKNINALYRFLPAVQGDECTSQNGV
                     LIREKDGKPFTGRIHSESGSTLSVYTYKDGRLDGLDVVYYNGAVKETGFWKEGKQDGL
                     FTLYTTEGVLVDYANFRDGERHGLTRQYDAKTGRMTCEGNFKNGQMEGTWTQYDPYTG
                     MAVIEQTYRDGALHGPAKQYYEDGQLHIDMTYENGIPQGPYKAYYPGGQIQVEDSLEN
                     GSYSSHVKMYEEDGTPIEITWGTSGSGIGDTKKEEVTITEE"
     gene            complement(5178..5315)
                     /locus_tag="ACZPCR_11460"
     CDS             complement(5178..5315)
                     /locus_tag="ACZPCR_11460"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231513.1"
                     /translation="MNGVVILVGLLLAAAILALFLEKNWFGLLLCVFALFLIFGTGRH
                     T"
     gene            complement(5505..6299)
                     /locus_tag="ACZPCR_11465"
     CDS             complement(5505..6299)
                     /locus_tag="ACZPCR_11465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002600173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialate O-acetylesterase"
                     /protein_id="HIR1231514.1"
                     /translation="MAGRGYLYEVTPIYNENIFMLRNGRWQMMTEPIHFDRSVAGAGP
                     AASFAQAWCSANKDEQIGLIPCAEGGTCIDEWDRKGPLFRHAVSEAKFAMETSELTAI
                     LWHQGESDSCGGRYKNYYQKLSTLVNSFRKELDVPEVPFIVGGLGDYLGKSGFGKSSV
                     EYNFINQELHKYAENNRNCYFVTGKELNPNPDGIHINAESQRRFGIRYFEAYRTKSNV
                     DRPLDNETELVKAYCEKEQTIAEKRYRALEQFTLGKGSMEEVMKFF"
BASE COUNT         1531 a         1978 c         1296 g         1858 t
ORIGIN      
        1 tctcaatata actacacaga tcccagaaag attttttgtc aaatttattc tcttcatgaa
       61 gaaaataaag gaaactttta tttgccgcgt ttatattatc atctattatc cccaccatct
      121 actcctttct gttgtccaga atcgattttt attttctctt ccacatcata gcgacagcgg
      181 cggtatttgc taaaagcata attatcacat atcctgttaa cacataaaac atagatggca
      241 cgacatctag taaagcgctc caatcctctc cctctttatt tttcttcagc atagtttcgt
      301 ctgtccggtt ctgccacaaa tccagcttcc gccatgattt ccaacagttc ctgcgcgctt
      361 tgttttatct tatattccaa ttcttcccgg taaaggggaa tgacctggta aaaattcacc
      421 ggtctgtctc cgggcagctg gcagatgaag ccgttttctt ctatattctt cggttctgtc
      481 aaaacggcgg cgcaaagctt cgtgttctct gcaaagggct ttttgttatc caccgtatgt
      541 ccccagccca gccaggtatc cgatgtaatc ggcaggcggg ccagcgtttt cagcagacgc
      601 actggccagt accatttctc gtccttcata gattcctgat ccagcttcca gtcaggcggc
      661 aaggcgatgg ccagctccgc acgttccagt ttatactccg ccaattcccc gggcacgttc
      721 atcggacggg cccccatgcc catcgtaacc agcgtgacat aatcccgctc cccttccgga
      781 ggaatcatac agacgtccac atggatatcc ggggatacca gctcatgaaa tacgttttca
      841 atggttccga agcaggccga aatatggcgc tctaccacat ccatctcctc ctctgtataa
      901 aacgccgtat ctcttccctc ctctgacgac cagaaggaac cctctatctt cgttccatcc
      961 gggcgcagga aaatctgaaa atactcctcc gccccgcaca gctggtagaa aaggccaatc
     1021 tggcagtcca ggcccaccag cgccgcattg agctttgccg ctctgccgtc cagatgattc
     1081 cgctccagcc accgcccgtc tgaaagccag ctttttacct gtctcagcca gtctgcattc
     1141 agcttggaca tacccgcctc gttcatctgg aagaccagat caatcgtact gcctttcacc
     1201 gtatagggaa attgggtata gggcgcgttg ggaacgtact gctttggctt cgggccgaat
     1261 atttcccaga aacgctccag tccctcctga tttacagtaa tacaggaaat ggatctccgt
     1321 ttattttctg cgtcctcatc ccttccctgc tgaagcgcct gatctgcgcc tggattgatc
     1381 cagtggtatt ccatccgctc cagcggctct ccggcctcaa tctctttctt taatgtcaga
     1441 aactcatagt cgcccggttc cagcaaaagg ccgcgggctg cagcctccag cgcgccttcc
     1501 ctgtccccaa aatgggctct gagctttccc gcctgcagcc agatccacgg gtaatccggt
     1561 tcttcctttg ttccctgctc cgcataatcc agagcctcct ccaggcgtcc gcagtacgtc
     1621 agcgccaccg aataccggta gtaccatgtg gcgcagcctt tggcgttttt ctcagaatcc
     1681 ggcatccact gggccgcctt gtaataatac cggtattcat ccagattgct gcaggcaaag
     1741 gaataccaca gggctatctg cagatcctgg cgggcctggc gctccgtaaa ttttcctgtc
     1801 tccacgcccc gtttcacaaa gtcctccaga tactgaagca ttttcccaaa atacccggaa
     1861 atgccgtcgt caaacgcttc caggttttct atatcctctg ccataagcag ggatccggtc
     1921 tccggatcga tctgcggttc tttctcctgt tcccacagcc gcactgctcc cagccccctg
     1981 cggaatacat ggaaaccgcc gcaggccagc tctgtcccgg caaaaaagtc cctggccgca
     2041 tccagcacag ccgggagatc ccaggcaata aagtccagat atccatagta caggccagtg
     2101 gctcctccca gaaaatcagc cgcgtcgtcc cccgcctggc ctctgaccgc ctcctgaagc
     2161 gcgtcccgga attttaaaat ctgttcagcc ctgttttccc ctgaaaagcc ttccagcgga
     2221 aaatataaaa atccggctgc aattccatcc atgtgatact cgtctgccgt ttcgctctcc
     2281 ccgctcatat attcgttaat aagcactggc agacgggcgg aaccggagaa gacgtcaaac
     2341 cgccagtcag cctccggatc ctccaccggc ttcatttcat agcccacata gctgctgtcc
     2401 aggtagctct ctgcatcgtc ccacagactg cactccatat ccaaaagcgt ctggggaagc
     2461 tcagaaagca ggaaggacgg ttcctccggc ggctgctctg ttatatctaa acggccaatc
     2521 agcgcgacag aagatatttc tcccagcgtc tggtcaacga gcgtgtacaa aatccaccac
     2581 gccctgctct catcctctct catcagcgga atcagctttt cgcaccagag cgtcagaaaa
     2641 atccggccgt cctcctgcct ggcccatgtc tgcacatcct ccgcctgaat ctctgtttct
     2701 cctgtccgga ggataaactc ctttgacggc tgacgcccca ccaaaatgtt ccagtgttcc
     2761 cggactggct ccggcgcatg gcgtttaaaa taaacgagag gaaacaggct ggatcggacg
     2821 ccctccgcgc tgagaatcag ctcatatttt cccccgttaa agcccagctc aaaggcagga
     2881 aaatggaagg ccagttccag ggcggtgctg cattgctcca tcagctcctc tccccgctcc
     2941 cgcattgtat cagagtccat aatactgcga agctccttct caatctctgc aaaggcggcc
     3001 caggcctcct ctgtcctctc cctgaaattt ttatcaaacc ggggcagaac cagacggctg
     3061 cggcagtctt caataagctc ctccgtgtcc tcatcccctg gacgagctgc cagcgcctgt
     3121 tcaaaataac gcagggcagg cccctcctga tccagatagt aataggcata tcccatccgg
     3181 aaattccagc tgtgatcgcc tgcaaagtat tcctcatgag gttccagcag ggcaatggcc
     3241 ttctgaaaca attccttttc cccaggctgc gctaaattgt tgtaagctct ggccagctcc
     3301 gaatcctcct ccggcgtgcg ctcctcagcc ggtatttttt ccagggcgtc tattattttc
     3361 tgaaattcgt cgtttttatt ccatctttgg cactgttcca gtaaagtcat atcgtctcct
     3421 cctccgctct gttttttcct gttttcctat tctctctgtc acattattct tctgtaatcg
     3481 taacttcctc cttctttgta tcgccaatcc cgctgccgga tgttccccat gttatctcta
     3541 taggcgttcc atcctcctca tacattttaa catggctgct gtaggatccg ttttccagac
     3601 tgtcctccac ctggatctgg cctccggggt aataggcttt ataaggccct tgcggaattc
     3661 cgttctcata agtcatatca atatgaagct ggccgtcctc ataatactgc tttgcaggtc
     3721 cgtgaagcgc accgtcccgg taggtctgct ctatcacagc catgccggta tatggatcgt
     3781 actgcgtcca ggttccttcc atctggccgt ttttaaaatt cccctcacag gtcattctcc
     3841 ctgtttttgc atcatactgg cgcgtcaggc cgtggcgttc cccatccctg aagtttgcat
     3901 aatccaccag aactccttct gtggtgtaga gagtaaagag gccgtcctgc ttcccctctt
     3961 tccagaaacc agtttccttt acagcgccat tataatagac gacgtccaga ccatccagcc
     4021 taccgtcctt ataagtgtaa acggacagcg tactcccact ttcagaatga atccgtccag
     4081 taaaaggctt tccatccttc tcacggatca gcactccgtt ctggctggta cattcatccc
     4141 cttggacggc aggaagaaaa cgataaagcg cgttgatatt tttataagcc agccagccgg
     4201 ctgccgacag caggacagcc agaacaacgg ctgatactgc cgctcttttc tttctgtttc
     4261 cccggctctt tttcgtattc ccaggttcct ccgtccttgt ttcctctgtc cagccagatc
     4321 ccgtttctgt gggccagaca gctgccgtct ctgtccgcag ctccccaata tgctgtctcc
     4381 attcctgcca ggttccttcc ttctcccacc tggcggttaa aactctcttc cgtccctgaa
     4441 tcattccgga ataaagcgca tccaacgcag aaatcagctc cttttccgac tcctcgtcag
     4501 cagaaaacgc ccgtacattc tgcaggtccc aggatccgcc gtcaaactgg ccataccggt
     4561 taaattccgt aaaaagctct gcaaatatca gatagatctc atcaaaataa tctgcatttt
     4621 ccggaacgtc atcgagaaaa gagagatttc tgcacatggc aaacagttcc tgaagcgtcc
     4681 acataggatt tctctgcgcc tcctcctcca aaatctccct cagcgtctgc acagtttgat
     4741 tctccgcata catatagtat ttcatctcca cacctccatt cgggaaataa gaaagaattc
     4801 tgctctgcag aattctccgc ctgcggaaca ttttttattt cataggacgc tctttcctat
     4861 gaaataaaaa accccgcgct gtactgccat cgcagcagct tagcgcaggg catgaaaagc
     4921 cgtgaaagga aaaccccatc catggccaga tgcggtctcc tcgcaaaatc atttattttt
     4981 atatcgaaac accgaaactg gcggtgcctc caccattgag ccatagacgg acctttctta
     5041 ccatgtggtt tacagcttgt atcaactgcc tttattatat catagattct tgtctaattc
     5101 acctgttttt ggctttggct gacaaaagac agcggtcttc tttccctgct tccatttccc
     5161 aaaatctgcg gtctctttta tgtatggcgt cctgtgccaa atatcaaaaa cagggcgaaa
     5221 acgcacagga gaaggccaaa ccagtttttc tccagaaaca aggctaaaat agcagctgcc
     5281 agcagaaggc cgacgagtat tacgactcca ttcataatcg ttatctccta tttttgtaat
     5341 ttcatcatgt tctgtccttt ctttttcgac agcagcgctg cccggctctc cgaaaagccg
     5401 gaatggcatt caatcacatc atgagaaagt atctcaaact ccgcagacaa gtccagcccc
     5461 ctataatcct cctccttgcc gttttcatca cctgcaaggc gtaatcagaa aaatttcatt
     5521 acttcttcca tggaaccttt tcctaacgta aattgctcta acgctctgta tcttttttcg
     5581 gcaatggttt gttctttttc acaatatgct tttactagct ctgtttcatt atctagtggc
     5641 ctgtccacat tcgatttggt gcgatatgcc tcgaaatatc tgattccaaa tcttctttgg
     5701 gactccgcat tgatgtggat tccgtctgga ttcgggttta attcttttcc agtcacaaaa
     5761 taacaatttc tattgttttc cgcatattta tgtaattctt ggttgatgaa attatactct
     5821 acgctgcttt tcccaaaccc tgacttgccc agataatctc ctaaaccgcc gacaataaac
     5881 gggacttccg gaacatccag ttcttttctg aacgaattaa ccagggtact aagtttctga
     5941 taataatttt tatatcttcc gccgcagctg tcgctttccc cctgatgcca taaaatggca
     6001 gtcagctcgc ttgtttccat agcaaacttt gcctcgctga ctgcatggcg aaacagaggt
     6061 cctttcctat cccattcatc aatacaagta cctccttccg cgcagggaat aagtccaatt
     6121 tgttcatctt tattagcact gcaccatgct tgagcaaacg atgctgccgg gccagcaccg
     6181 gccactgatc tgtcgaagtg gattggctca gtcatcatct gccatctgcc atttctgagc
     6241 ataaaaatgt tttcattgta aattggcgta acctcgtata aatacccacg ccctgccatg
     6301 tttgattgtc ctattaagta aaactgattt catgtttcaa tctcctgcca ttataattct
     6361 aatcttttat ccaccatgct tttgtgttat aatctaagct aaaactttcc tccacgaaca
     6421 ggaagagttc ttcctctggt ttcatcgatt ttattccaaa aatactgatc gccaatttgt
     6481 gcagtcacaa gcttcccttc tttcatctgt tattgtattc tgctcattgt ttaaaaccaa
     6541 tatgcttccc caaagagtca atttagaaaa ctgagctttt ccacatccac gttatcaaaa
     6601 gtcacattat aaataggctt tgcctctgta ccttgaagca ccaatgcagc tacattcacc
     6661 ttt
//
LOCUS       DBMDUW010000087         6318 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_5046_length_6318_cov_4.231301, whole genome shotgun sequence.
ACCESSION   DBMDUW010000087 DBMDUW010000000
VERSION     DBMDUW010000087.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 6318)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 6318)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6318
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5046_length_6318_cov_4.231301"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            42..218
                     /locus_tag="ACZPCR_11470"
     CDS             42..218
                     /locus_tag="ACZPCR_11470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231515.1"
                     /translation="MADRNSYNENSLKNRDDSQNRSQNKSQNSSKDCGRDSSRNSSRN
                     SSRNKADNCSRNND"
     gene            385..714
                     /locus_tag="ACZPCR_11475"
     CDS             385..714
                     /locus_tag="ACZPCR_11475"
                     /inference="COORDINATES: protein motif:HMM:NF012790.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HIR1231516.1"
                     /translation="MYQMIPVRRLDQFLDQGFSGTIIDLRSPEEYKRFHLKGAVNREL
                     EELLNQPEEIDRTLPVLFYCSRGSESLRAAVCFSRMGFRAFDVAGGIQYYCGHNGEKQ
                     AFGGFEK"
     gene            861..2033
                     /locus_tag="ACZPCR_11480"
     CDS             861..2033
                     /locus_tag="ACZPCR_11480"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009295746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="THUMP domain-containing class I SAM-dependent
                     RNA methyltransferase"
                     /protein_id="HIR1231517.1"
                     /translation="MERFELIAPCHFGLEAVLKKEITDLGYEITLVEDGRVTFEGDAE
                     AIARANVFLRTAERVLLKAGSFTAVTFDELFEKTRAIPWERYIPRDGKCWVTKASSIK
                     SKLFSPSDIQRIMKKAIARRLQEAYDLGQQPLSETGSEYPLRVFFFKDQVTVGIDTSG
                     DSLHKRGYRTLTSKAPITETLAAALILLTPWKKDRILVDPFCGSGTFPIEAAMIAANI
                     APGMNRSFLAEGWKNLVPRKHWYNAVDEAMEVMDDSVQVDIQGYDADGDIVRAARENA
                     ARAGVDHMIHFQQRPVAELSHPKKYGFIITNPPYGERIEEKKNLPELYRQIGERYREL
                     DAWSMYLITSYEDAERYIGRKADKNRKIYNGMMKTYFYQFLGPKPPRRRPEEKNEG"
     gene            2033..3766
                     /locus_tag="ACZPCR_11485"
     CDS             2033..3766
                     /locus_tag="ACZPCR_11485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009295747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lectin like domain-containing protein"
                     /protein_id="HIR1231518.1"
                     /translation="MRRRQFIALLAVLALSFCILKFGGRLAVEDVREGEMAGSYPAEW
                     YEMVSRETNEKGIQVVVDGKEKKLKTSVRMAEAGGFLIPVSELRELFSCTAHTYDDTI
                     LVMEKAGRRASIAIGEREMTLFRTSEDGQGEEKISLNAPLTVRQGQLFVPADTPARAF
                     GYETDWDAEQSVLSFTSQNPEEKVLPRSYDYRTVGRAPAVKNQGSLGTCWAFASLMAL
                     ESRLLPEQSFDFSEDHMSLRNSFQMDQNDGGDYTMSMAYLLSWQGPVLESEDPYGDSW
                     SPEGLSPALHLQEIQILPEKNYEAVKEAVYFTGGVQSSLYTSMADGEESSDYYNKEEG
                     AYCYTGDRRPNHDVVIIGWDDDYPKENFPVQPEGDGAFICANSWGGAFGEQGYFYVSY
                     YDTNIGIHNIVYSRADSSDYYDKIYQTDLCGWVGQLGYGKEDAFFANIYQAEEDEELW
                     AAGFYATDEDTQYEVYVVNNAAGSADFGRRRSVARGKLEHAGYYTIDFPKPAAVKAGE
                     RFAVIVSIRTPGSVHPVAIEYNAPDKKTKVDLSDGEGYISLRGTAWDRVETEQNCNVC
                     LKAYTRRPADR"
     gene            3875..4483
                     /locus_tag="ACZPCR_11490"
     CDS             3875..4483
                     /locus_tag="ACZPCR_11490"
                     /EC_number="3.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003501656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="XTP/dITP diphosphatase"
                     /protein_id="HIR1231519.1"
                     /translation="MAEKLIFATSNQGKLREIRSILGDLGLEVISMAQAGFHDEIEEN
                     GTTFAQNAAIKARAVWNQTGGLVLADDSGLVIDYLNGEPGVYSARYMGDAPYSEKNRA
                     LIQRMEQAEGEERSARFACVIAAVLPDGREIATEGFMEGRIAHEPAGEGGFGYDPILY
                     LPEYGKTSAELTMDEKNRISHRGKALELMKEKLKEVFGGTER"
     gene            4480..4974
                     /locus_tag="ACZPCR_11495"
     CDS             4480..4974
                     /locus_tag="ACZPCR_11495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HIR1231520.1"
                     /translation="MKVLIVSDTHRRNGNLQEVIERTAPFDMLIHLGDAEGSEDLITA
                     WCMEQNQDCQVHMVLGNNDFFSCLDREKEIAIGPHRAFLTHGHFYSVSVGTERLEEEA
                     GSRGVDIAMFGHTHKPYLETRNGLTVLNPGSLSFPRQEGRRPSYMIMEADDSGNVQYQ
                     TCYL"
     gene            5350..5424
                     /locus_tag="ACZPCR_11500"
     tRNA            5350..5424
                     /locus_tag="ACZPCR_11500"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5385..5387,aa:Pro,seq:tgg)
     gene            5433..5503
                     /locus_tag="ACZPCR_11505"
     tRNA            5433..5503
                     /locus_tag="ACZPCR_11505"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5465..5467,aa:Gly,seq:tcc)
     gene            5606..5679
                     /locus_tag="ACZPCR_11510"
     tRNA            5606..5679
                     /locus_tag="ACZPCR_11510"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5640..5642,aa:Arg,seq:tct)
     gene            5721..5794
                     /locus_tag="ACZPCR_11515"
     tRNA            5721..5794
                     /locus_tag="ACZPCR_11515"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5755..5757,aa:His,seq:gtg)
     gene            5813..5884
                     /locus_tag="ACZPCR_11520"
     tRNA            5813..5884
                     /locus_tag="ACZPCR_11520"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5845..5847,aa:Gln,seq:ttg)
     gene            5895..5967
                     /locus_tag="ACZPCR_11525"
     tRNA            5895..5967
                     /locus_tag="ACZPCR_11525"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5928..5930,aa:Lys,seq:ttt)
BASE COUNT         1793 a         1341 c         1793 g         1391 t
ORIGIN      
        1 tactgactgt gtaaccattg aaacgtcagg aggtaatgaa catggcagac agaaacagct
       61 ataacgaaaa cagcttaaag aacagagacg attctcagaa cagaagccag aataagtctc
      121 agaactcttc taaggactgc ggcagagaca gctccagaaa ttcttccaga aacagcagca
      181 ggaataaagc tgacaactgc agcagaaaca atgactaaaa aagcagaaca gacagaagaa
      241 aaataaaaca aaaacaggcg gggaatcgtt ttccgggctt ttatgagagg caggaggacg
      301 gttccccgtt tgctttgccc ggatggaaca ggctctgccc tgctggaata caataaaata
      361 agaaacaagc acaggagaac gattatgtat cagatgatac cggtgcggcg tctggatcag
      421 tttttggatc aggggttttc cggaaccatt atagatttgc gaagtcccga ggaatacaag
      481 cgctttcatc tgaaaggagc ggtgaaccgg gagctggaag agcttttaaa tcagccggag
      541 gagatagaca gaacgcttcc ggtgctgttt tactgctcca gaggaagcga gagtctgcgg
      601 gctgctgtgt gtttttcgcg gatgggcttc cgcgccttcg acgtggcggg aggaatccag
      661 tattattgcg gacacaatgg ggagaaacag gcttttgggg gctttgagaa gtaaaacact
      721 ggccctcagc cattgacagg agaaagtggt taaattagaa tagaaaatgc agatccctca
      781 tagaaaagta aagggattcg gtcacagggc ggccgcagca tgcggcctgc acagcataag
      841 aaagataaga ggaacgagga ttggaacgat ttgaactgat tgccccctgc cacttcggtc
      901 tggaggcagt tctgaaaaaa gaaattacag atttgggcta tgagatcact ctggtggagg
      961 acggccgcgt gaccttcgag ggagacgcgg aggccattgc cagggcgaat gtgttcttga
     1021 gaaccgcaga gagggttctt ttaaaggcag gcagctttac ggctgtgacc tttgacgagc
     1081 tgtttgaaaa gacaagagcg attccatggg agcgctacat tcccagggat ggaaaatgct
     1141 gggtgaccaa ggcttcttct attaaaagca agctgttcag cccgtcggac attcagagga
     1201 ttatgaaaaa ggccattgcg agacgtctcc aggaggctta tgatctgggg cagcagcctc
     1261 tttcggagac aggaagcgaa tacccgctgc gtgtgttttt ctttaaggat caggtgacgg
     1321 tgggcatcga taccagcgga gactcccttc ataagagagg atacagaacg ctgaccagca
     1381 aggctccgat tacagagact ctggccgcgg ccctgattct cttgactccc tggaagaagg
     1441 acaggattct ggtggatccc ttctgcggaa gcggaacctt ccctatcgag gcggccatga
     1501 ttgcggccaa tattgcgcca ggcatgaacc gttccttcct ggcggaggga tggaaaaacc
     1561 tggttccgag aaagcactgg tacaatgcgg tggacgaggc gatggaggtt atggacgaca
     1621 gcgtccaggt ggatatccag ggctatgacg cagacggaga tattgtccgg gcggccaggg
     1681 agaacgcagc cagagccggc gtggatcaca tgattcactt ccagcagagg ccggtggccg
     1741 agctgagcca tccgaaaaag tacggcttta ttatcacgaa cccgccctac ggcgagagaa
     1801 tcgaggagaa gaagaacctg ccggagctgt accgccagat tggagagcgt tacagggaac
     1861 tggacgcctg gtccatgtac ctgatcacct cctacgagga tgcagagcgt tatattggaa
     1921 gaaaagctga taaaaacagg aagatttata atggaatgat gaaaacgtat ttttatcagt
     1981 ttctggggcc gaagcctccc agaaggcggc cggaagaaaa gaatgaggga taatgaggcg
     2041 cagacagttt atagcgctgc tggcagttct ggctctctcc ttctgcatcc tgaaattcgg
     2101 cggccgtctg gctgtggagg acgtgcggga gggggagatg gctggaagct atccggcaga
     2161 gtggtatgag atggtatcca gggaaacgaa tgaaaaagga attcaggtag tggtggacgg
     2221 gaaagaaaaa aagctgaaga cgtctgtcag gatggcagaa gcaggcggtt ttctcattcc
     2281 tgtaagcgaa cttcgggaat tgttttcctg tacggcccat acatatgatg acacaattct
     2341 tgtaatggaa aaggccggac ggcgggccag cattgccata ggggagagag agatgactct
     2401 tttcaggacc agcgaggacg ggcaggggga ggagaagatt tcactgaacg ctcctctcac
     2461 agtcaggcag ggccagctgt tcgtgccggc tgatacgcct gcccgcgcct tcggctacga
     2521 gacagactgg gatgccgaac agtccgtcct ttcctttacc tcccagaatc cggaagaaaa
     2581 ggtccttccc agatcttatg attaccggac tgtggggaga gcgcctgcag tgaaaaatca
     2641 gggaagcctg ggaacctgct gggcgttcgc ctctctgatg gctttggaaa gccgccttct
     2701 tccggaacag tcttttgatt tttcggagga tcatatgtcc ctccgaaaca gctttcagat
     2761 ggaccaaaac gacggagggg actatacgat gtccatggcc tacctgcttt cctggcaggg
     2821 gccggtgctg gagagcgagg acccttatgg ggacagctgg tctccagagg ggctttcccc
     2881 ggctcttcac ctccaggaga tccagatcct tccggagaag aattatgagg cggtaaagga
     2941 agccgtttac tttaccggag gggttcaaag ctctctttac acctccatgg ctgacgggga
     3001 agagagctct gactactata ataaagaaga gggagcgtac tgttatacag gagacaggcg
     3061 tccgaaccac gatgtggtga ttattggctg ggacgacgat tatcctaagg aaaattttcc
     3121 ggttcagccg gaaggagacg gcgcctttat ctgtgcaaac agctggggcg gagccttcgg
     3181 agagcaggga tatttctacg tatcctatta tgataccaac attggaattc ataatattgt
     3241 atacagccgc gccgattcct ctgattacta tgacaaaatt taccagacgg atttgtgcgg
     3301 atgggtagga cagctgggct atggaaagga agacgctttt tttgccaata tctaccaggc
     3361 agaggaggac gaggagctgt gggcagccgg cttttacgct acggatgagg atacccagta
     3421 cgaggtgtat gtggtgaaca acgcggcggg aagtgcagac ttcggcagac gcagatccgt
     3481 ggccagagga aagttagaac atgcgggcta ttataccatt gattttccaa aaccagctgc
     3541 cgtgaaagcg ggagagaggt tcgctgtgat tgtgagcatc cggacgccag gatccgttca
     3601 tccggtcgcc atagagtata acgcgccgga caagaaaaca aaggtggact taagcgacgg
     3661 agaaggctac atcagcctgc ggggaacggc ctgggaccgc gtggaaacag aacagaactg
     3721 caacgtatgc ctgaaggcgt acacaagacg gcctgcagac aggtaaaagg cctgaagcac
     3781 aaaaagaaaa gaatgaaata tctgaatcca taaaaacagc tgacaggagc gcggaacgtg
     3841 ctggataaaa gaaacaggat acaggaggag aaacatggca gagaaattga tatttgcaac
     3901 atccaaccag ggaaagctga gggaaatccg cagtattctg ggcgatttag gcctggaggt
     3961 catttctatg gcccaggcag gatttcacga tgaaatagag gagaacggaa caacctttgc
     4021 acagaacgcg gctattaagg caagagctgt gtggaatcag acgggagggc ttgttctggc
     4081 agacgattct ggccttgtca ttgattatct gaatggagag ccgggagtat actctgcccg
     4141 ctatatgggg gacgctccct actcggagaa aaaccgcgcc ctgattcagc ggatggagca
     4201 ggcagaagga gaggagagaa gcgcccgctt tgcctgcgta atcgccgccg tactgccgga
     4261 tggcagggaa atcgccacag agggctttat ggaaggacga atcgctcatg agccggcggg
     4321 agaaggcgga ttcggctatg atccgattct gtatcttcca gagtatggaa agacctctgc
     4381 tgagcttact atggatgaga aaaaccgcat cagccatagg ggaaaggctc tggagctgat
     4441 gaaagagaaa ttaaaggaag tatttggggg aacagagaga tgaaggtttt gattgtgagt
     4501 gatacccacc gccgcaacgg aaatttacag gaggtgattg agcggaccgc gccgtttgac
     4561 atgctgatcc atctgggaga cgcggaggga agcgaggatc tgattacggc ctggtgcatg
     4621 gaacagaacc aggactgcca ggttcatatg gttttaggca acaacgactt tttctcctgc
     4681 ctggatcggg agaaggaaat tgccataggg ccgcaccggg catttctgac ccatggccat
     4741 ttttacagcg tgtctgtggg aacggagcgc ctggaagagg aggcaggatc ccgcggtgtg
     4801 gatatcgcca tgtttggaca cactcataag ccgtatctgg agacaagaaa cgggctgacg
     4861 gtactcaatc caggaagtct ttcctttccg cgccaggagg gcagaaggcc aagctacatg
     4921 attatggagg cggatgactc aggaaacgtc cagtaccaga cctgctatct ttaaaaaatt
     4981 caaaaaaaga cttcattctt ccagaggaga cacagcgtct cctctgaaat tttatggaga
     5041 gagggccggg agagaaaaaa atatgtttga gaaggtaaaa aagaaggaaa aaaatattta
     5101 ataacaaaaa ttcgaaacag acaaaaataa acaggtataa acaggtttgc acaaaaagaa
     5161 aacagacaaa aagaataaaa aaaatgaaaa attagacgaa aaaagttgta aaaaatgttg
     5221 acattggggt tgctatagta tataatagtc cttgcttgaa acgaagcgct tctgaaaaag
     5281 ccttccgaag agagcaaaag aaaaattgat aaagttttat gaaacaattc ataaagccct
     5341 atcagaaaac ggggtgtggc tcagcttggc tagagcgcct ggtttgggac caggaggtcg
     5401 caggttcgaa tcctgtcacc ccgactgaat atgcgggtgt agttcaatgg tagaacacca
     5461 gccttccaag ctggatacgt gggttcgatt cccatcaccc gctctgtaca gaagcgaaag
     5521 ctgatgtacc aggcagttgg cggtaagcct ctgcaggaaa aagtgaaatg tcaatttgtt
     5581 tggcagtctc cacaaaaaaa catatgagtc tgtagctcag ctggatagag caacggcctt
     5641 ctaagccgtg ggtcgggggt tcgaatccct tcaggctcgt tgaatccgaa aggattatat
     5701 cccttcggat tcgttttatg gtgggtatag cgcagttggt tagcgcgcca gattgtggct
     5761 ctggaggcct agggttcgaa tccctatacc caccctcccg aatgggtttt gttgggctat
     5821 cgccaagcgg taaggcacag gactttgact cctgcattcg ttggttcgaa tccaactagc
     5881 ccagtttata ttatggggta ttagctcagt cggtagagca cttgactttt aatcaagttg
     5941 tccggggttc gaatccccga tgcctcagtt attttatgaa agccggtttt ccttgaaaat
     6001 aaaggaaagt cggttttttt gtttgccggt ttacagggaa aatcccagac acccttgatt
     6061 tttattaaat cttatataca taagaatcta agtgtgataa acggttttct aaagcaatta
     6121 tttcatgagc aaaatgctca tatcgcttcg tggtttcaag acttttatgt cccatgataa
     6181 tacttaaatc aaatacattc gaattgccag accgtaacac gacatacgca tgaattgttt
     6241 tccttcctct ttttcaaaat atcttgtttt taaaaattta atacctgttc caaaaactct
     6301 gctgggttca tactgatt
//
LOCUS       DBMDUW010000088         5627 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_5678_length_5627_cov_3.768368, whole genome shotgun sequence.
ACCESSION   DBMDUW010000088 DBMDUW010000000
VERSION     DBMDUW010000088.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 5627)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 5627)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5627
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5678_length_5627_cov_3.768368"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            311..970
                     /locus_tag="ACZPCR_11530"
     CDS             311..970
                     /locus_tag="ACZPCR_11530"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: protein motif:HMM:NF009676.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HIR1231521.1"
                     /translation="MKILVTGFEPFGSHHSNPSWDAVEALPEEIEGVQIVKRKLPVSF
                     RRFSAPLEAAIEEERPDGLICVGLAGGEDKVSVERVGINLMEARIPDNDGFQPFDTPI
                     CPDGDTAYFSTLPVKRMAKAVESRGIACCMSYSAGTFVCNAALYTGLYLSSCRYRFMK
                     CCFIHVPYDETMEEALAGQPFMKRETLTEALTAAAGEAARALKAGKGSGDLHEAADTI
                     F"
     gene            1067..2239
                     /gene="iadA"
                     /locus_tag="ACZPCR_11535"
     CDS             1067..2239
                     /gene="iadA"
                     /locus_tag="ACZPCR_11535"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008798 - beta-aspartyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HIR1231522.1"
                     /translation="MILIKGVHVFAPQDMGMKDVLVGGTKILKIGDNLPAEEAYGVEV
                     IDGTGKILMPGLIDAHVHILGGGGEGGYRTRTPELMLSDALEGGVTTIVGCLGTDGTT
                     RTMTNLIAKARGLEEEGISTYIYTGSYQVPVRTLTGNVMDDLILIDKAVGTGEIAISD
                     HRSSQPSREEFAKIVADTRVGGILSGKAGLVNIHLGDGKEQLSYLRYVLTETQIPASN
                     MLPTHINRSRRLMEDGIDYAKNMGGYIDLTTSSDPDFLDPEEVKASTGLKMALDAGVP
                     ADHVTFSSDGQGSLPVFDKEGNFLHLGVGKVSSIYREMRDAVQKDGVSLTDALRAVTE
                     NPAFLLKLPDKGRIAENADADLVLADSETLEIDSVMARGQLMVSGRRVLKRGTFEY"
     gene            2257..3771
                     /gene="yfcC"
                     /locus_tag="ACZPCR_11540"
     CDS             2257..3771
                     /gene="yfcC"
                     /locus_tag="ACZPCR_11540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003506942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HIR1231523.1"
                     /translation="MEKQKKKFQMPHTYLIIFLVICAAALMTLFIPLGTYQEKEITYM
                     QDGEEKTKTVLDPDSFEYVLDENGNKVTKAAPLWGTEDFGGQGILNFVFEGMTVGDKN
                     GTAVGIIAFILVVGGSFGIVLRTGAVDAGIMRVIAITKGREILLIPILITLFSLGGAV
                     FGMGEEALPFVMILAPMFVAMGYDAVVGIVCSYVATQIGFGTSWMNPFSLAVAQGIAG
                     IPVMSGAAFRIALWVFFTGLTIVFTMRYASKIKKNPRLSVAYESDAYYRNEFSAEGRE
                     ELPFTLGHKLVLLTLLATIVWTIWGVLVKGYYIPEIASQFFVMGFVAGIIGVVFKLNG
                     MELNDIAKSFDKGAADLLGAALCVGMAQGIILVLGGTSATDGTVLNTILHTIGESMKG
                     LPPMISAWLMYVFQSVFNFFVVSGSGQAALTMPIMAPLADIVGVSRQTAVLAFQLGDA
                     FTNFIVPTSGCLLGALAAARMEWGQWARFQIKFQALLFVCASAAVIIAVMIGFA"
     gene            4249..5472
                     /gene="tyrS"
                     /locus_tag="ACZPCR_11545"
     CDS             4249..5472
                     /gene="tyrS"
                     /locus_tag="ACZPCR_11545"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002595262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HIR1231524.1"
                     /translation="MQIYEELVARGLIAQVTNEEEIKKMVNEGKATFYIGFDPTADSL
                     HVGHFMALCLMKRLQMAGNKPIALIGGGTGYIGDPSGRTDMRSMMTPEMIQHNCDCFK
                     KQMSRFIDFSDGKALMVNNADWLLGLNYVELLREVGPHFSVNRMLTAECYKQRMEKGL
                     SFLEFNYMIMQSYDFYMLFQKYGCNMQFGGDDQWSNMLGGTELIRRKLGKDAHAMTIT
                     LLLNSEGKKMGKTQSGAVWLDPNKTSPFEFYQYWRNVADADVLKCLRMLTFLPLEQID
                     EMDKWEGSQLNEAKEILAYELTALVHGGEEAQKAKEASKALFSSGNAANMPTAELSEE
                     DFTDGAIDILSVLQKSGLAPSRSEARRNVEQGGVAVDGTQVKDTKASFTKDQFAGDGI
                     VVKRGKKNFKRVVLK"
BASE COUNT         1427 a         1280 c         1652 g         1268 t
ORIGIN      
        1 acctgcacgg tctcccacca gaacctaaat ctggcgcgtc tgccaattcc gccatacccg
       61 caggactatt ttattatacg ggaggcagcg ggaaatgtca attcccatgc agagagtgag
      121 gaaggaaaaa tttacgctcc cggtcctctt atacagtctg ctcttacata tttataaaaa
      181 atccgtgaat aaatttgcga aaaccccatg acttttttct gcttctgtgt tagaatactc
      241 cgggattatc tgtaaacagg ctcctgcctc tggcttttga ggctggaacc tttcatacag
      301 ggaggaaaaa atgaagattt tggtgactgg atttgaaccc tttggttccc accactccaa
      361 tccgtcctgg gacgcagtgg aagccctgcc ggaggagata gagggagttc agattgtaaa
      421 gcgtaagctt cccgtctcat ttcggcgttt ttcagctcct cttgaggctg ccatagagga
      481 agaaagaccg gatggcctga tctgcgtggg gctggccggc ggggaggaca aggtgagcgt
      541 ggaaagggta gggattaatc tgatggaggc gagaatcccg gacaacgatg gttttcagcc
      601 cttcgatacg ccgatttgcc ctgacggcga tacggcctat ttttccacgc ttcctgtcaa
      661 gcgcatggcg aaggcggtgg agagccgcgg gattgcctgc tgtatgtcct actcggcggg
      721 aaccttcgtg tgcaacgcgg cgctgtatac gggactttat ctgtcctcgt gcagataccg
      781 tttcatgaaa tgctgcttta tccacgtgcc ctacgacgag accatggagg aagcgctggc
      841 aggacagcct tttatgaaga gagagacttt gacggaggct ctgactgcgg cggcagggga
      901 ggcggcccgg gcgctgaagg cagggaaggg aagcggcgat cttcacgagg ccgcagacac
      961 gattttttag cacatgggaa ctggcgcctg cgtttggagg catatggcct ctccatggaa
     1021 cgctgacagg atggttcaga ttcaaaaaca gaaaggaaac tgccatatga ttttgataaa
     1081 aggagttcat gtgtttgctc cgcaggatat gggaatgaaa gacgtgctgg tgggcggaac
     1141 aaagatttta aaaatcggag ataaccttcc ggcagaggag gcttacgggg tagaggtaat
     1201 tgacggaacg gggaaaattc tgatgcctgg cttgattgac gcccacgttc atatcctggg
     1261 cggaggagga gagggcggct acagaaccag gacgccggag ctgatgcttt ccgacgctct
     1321 ggaaggaggc gtgaccacca ttgtggggtg tctcggcaca gacggtacca ccagaaccat
     1381 gacgaatctt atcgccaagg ccagaggact ggaggaggag gggatctcca cgtatattta
     1441 tacgggttcc taccaggttc ctgtacggac gctgacagga aatgtcatgg atgatctgat
     1501 tctgattgac aaggcggtgg gcacagggga aattgccatt tcggatcacc gctcctccca
     1561 gccgtccaga gaggagtttg caaagattgt ggccgatacc agagtaggcg gcattctgtc
     1621 gggaaaggca gggcttgtga acattcacct gggagacggg aaggaacagc tttcctatct
     1681 gcggtatgtg ctcacagaga cgcagattcc ggcctccaat atgcttccga cgcacattaa
     1741 caggagcaga aggctgatgg aggacggcat tgactatgcg aaaaatatgg gaggctacat
     1801 tgacctgacc accagctcgg atccggattt cctggacccg gaggaggtga aggccagcac
     1861 agggcttaaa atggctctgg atgcaggcgt gcctgcggat catgtgacct tttcctctga
     1921 cggccaggga agtcttccag tttttgacaa ggagggaaac ttcctgcatc tgggagtggg
     1981 gaaggtttct tctatttaca gggagatgcg ggacgcggtt cagaaggacg gtgtctctct
     2041 cacggacgct ctgcgggctg tcacggaaaa tccggccttt ttgctgaagc ttcctgataa
     2101 ggggagaatt gccgagaacg cagatgcgga tctggtgctg gccgactctg agacgctgga
     2161 aattgacagc gttatggccc ggggccagct gatggtttca ggcaggcggg tgttaaagcg
     2221 ggggaccttt gaatattaaa aacaggagag tatgagatgg aaaaacagaa gaagaaattt
     2281 cagatgcctc acacgtatct tatcattttt ctggtaatct gcgcggcggc tctgatgacg
     2341 ctctttattc ctctgggaac ctaccaggaa aaagagatta cgtatatgca ggacggcgag
     2401 gagaagacga agaccgttct ggatccggac agctttgagt atgttctgga cgaaaacgga
     2461 aacaaggtga cgaaggcggc tcctctctgg ggaaccgagg acttcggcgg ccagggtatc
     2521 ttaaatttcg tgtttgaggg aatgaccgtg ggcgataaga acggcactgc agtgggcatc
     2581 atcgccttta ttctggtagt aggaggatcc tttggaatcg tccttcggac gggagccgtg
     2641 gacgctggaa ttatgagggt aatcgccatc acaaaagggc gggaaattct gctgattccc
     2701 attctgatca cactgttctc cctgggagga gcggtgttcg gcatgggcga ggaggccctt
     2761 ccctttgtca tgattctggc tcccatgttt gtggccatgg gatacgacgc ggtggtaggc
     2821 atcgtctgct cctatgtggc cacgcagatt ggctttggaa cctcctggat gaacccgttc
     2881 agcctggcag tggctcaggg aatcgccgga attccggtta tgtcgggagc agcgtttcga
     2941 atcgccctct gggtgttctt cacagggctg accattgtgt tcaccatgcg ctatgcgtct
     3001 aaaatcaaga aaaacccaag gctgtcagta gcctacgaat cggatgccta ctatagaaat
     3061 gagttcagcg cagagggcag agaggagctt cccttcaccc tgggccataa gctggtgctt
     3121 ttgacgctgc ttgccacgat tgtatggacc atctggggcg tgcttgtgaa gggctattac
     3181 attccggaga ttgcctctca gttctttgtg atgggctttg tggccggaat tatcggcgtg
     3241 gtcttcaagc tgaacgggat ggagttaaac gacatagcaa aatcctttga caagggagcg
     3301 gcagatctgc tgggggcggc tctctgcgtc ggcatggctc agggaattat tctggtgtta
     3361 ggcggcacca gcgccaccga cggaaccgtt ttaaacacga ttcttcacac catcggagag
     3421 agcatgaagg gactgccgcc aatgatttcc gcatggctta tgtacgtgtt ccagtctgtc
     3481 ttcaacttct ttgtggtttc cggatccggc caggcggctc ttaccatgcc gattatggct
     3541 ccgttagctg acattgtagg cgtttccaga cagactgcag ttctggcctt ccagctgggc
     3601 gacgcgttca ccaactttat cgtgccgacc tcaggatgcc ttttgggcgc gctggcagct
     3661 gccagaatgg agtggggaca gtgggccagg ttccagatta aattccaggc tctgttattt
     3721 gtctgcgctt ccgcggctgt gatcattgcg gttatgattg gctttgccta aattgcctaa
     3781 aattcctgat ttacaggctt gactttccta tggaaaccac gtacaatgag gaagtacaat
     3841 ctgatagatg gcagtgacgg gaaaaagtag ctgttttaca ccccagacag agagcagccg
     3901 gacggtgaga ggcgcctgga ggaagaatct gcgaatacat cccagagccc tgcaccgaag
     3961 gagagacttt tcgcaagaca gatttctgaa tgggaacgct gcacggaaga ctttttctgc
     4021 gtaggctgca gcgggattgc cgcacgttac agcggcagga gtataggaaa ctgtactcgt
     4081 tgaggaagag aggcgcgagc gtcttttcaa actaaggtgg taccacggaa atttaactcc
     4141 gtcctttgga tcaagcgatt caggggatgg agttttttta tttcatagga aaagcgtcct
     4201 atgaaatcaa tgaaattaag aaaacagctg caggaaagga gaaaaaacat gcagatttat
     4261 gaagaactgg ttgcccgcgg cctgattgcc caggtgacga acgaggaaga gattaaaaag
     4321 atggtaaacg agggaaaggc taccttctac attggctttg acccgacggc cgacagcctt
     4381 cacgtaggcc atttcatggc tctgtgcctg atgaagagac ttcagatggc cggaaacaag
     4441 cctatcgccc tgattggcgg aggaaccgga tacatcggcg atccgtccgg aagaacagac
     4501 atgagatcca tgatgactcc agagatgatc cagcacaact gcgactgttt taagaagcag
     4561 atgagccgtt tcatcgactt ctccgacgga aaggccctga tggtaaacaa cgcagactgg
     4621 cttctgggct taaattacgt agagctttta agagaggtgg gaccgcattt ctccgtaaac
     4681 cgtatgctga cagccgagtg ctataagcag agaatggaga agggattaag cttcctggag
     4741 tttaactaca tgatcatgca gagctacgac ttctacatgc tgttccagaa atacggctgc
     4801 aacatgcagt tcggaggaga cgatcagtgg agcaacatgt taggcggaac agagctgatc
     4861 agaagaaagc ttggcaagga cgcccacgcc atgaccatca ctcttctgtt aaactccgag
     4921 ggcaagaaga tgggcaagac tcagtccgga gccgtatggc tggatccgaa caagacctcc
     4981 ccgttcgagt tctaccagta ctggagaaac gtagcggacg ccgacgtatt aaaatgcctg
     5041 cgtatgctta ccttcctgcc gctggagcag atcgacgaga tggacaagtg ggaaggcagc
     5101 cagttaaacg aggcgaagga gattctggct tacgagctga ctgctcttgt ccacggcggg
     5161 gaggaggccc agaaggcaaa ggaagcttcc aaggccctgt tcagcagcgg aaatgcagct
     5221 aacatgccta cagcagagct ttccgaggaa gatttcacag acggagccat tgatattctc
     5281 tctgtcctcc agaaatcagg actggctcca tcccgctctg aggccagaag aaacgtagag
     5341 cagggcggag tggctgtaga cggaacacag gtaaaggata cgaaggcatc ctttacgaag
     5401 gatcagtttg caggcgacgg aatcgtggta aaacgcggta agaaaaactt caagagagta
     5461 gttctgaagt aggaatcaga aagcagaacg ctgcatggga gaaagataag acagaacggc
     5521 tggaaatgat atgctccctt tatgagagac agtgaaaaaa caaactgtca tcatgaaggg
     5581 agcaattcta tgtcacaaaa aggtaaacta aacacagaag aaaaagt
//
LOCUS       DBMDUW010000089         5338 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_5963_length_5338_cov_4.358793, whole genome shotgun sequence.
ACCESSION   DBMDUW010000089 DBMDUW010000000
VERSION     DBMDUW010000089.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 5338)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 5338)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5338
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5963_length_5338_cov_4.358793"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(203..1093)
                     /locus_tag="ACZPCR_11550"
     CDS             complement(203..1093)
                     /locus_tag="ACZPCR_11550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006773738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3881 family protein"
                     /protein_id="HIR1231525.1"
                     /translation="MHKYLRAAGFSMYQKNRDIKALLKCLSKEPKDSRCIQIDRDTDF
                     YELRAEIADGIGISMCGEMNEQNELEIEYYYPYLESSIETSTAECSIQRHTEKETYAG
                     LLDEYRVGISLIFYVTNGMEYRERILKRRKSTEVVSSNLAGFSVHGKILLPVKKTANQ
                     IAMAKVASRNRNNLLEAAKNGDPEAMESLTIEDIDLYSQASRRAAKEDLYTIIDTCFM
                     PSGIECDQYSIIGEIEEILLKKNRITGEELYDMKLECNDIHFRVCINKADLFGEPKVG
                     RRFKGKVWMQGRVFFDEALG"
     gene            complement(1174..1674)
                     /locus_tag="ACZPCR_11555"
     CDS             complement(1174..1674)
                     /locus_tag="ACZPCR_11555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006778086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4446 family protein"
                     /protein_id="HIR1231526.1"
                     /translation="MENSMLNNLLFDPAYLIIGLAALTLVLMILTLVCFSQYRKLYRR
                     YDMFMRGKDAETLEDIILDLMDEAAVRQATDKEGRDQLKSLSRQVRASYQKIGIVKYN
                     AFKGMGGNLSFVIALLDDNNSGFILNSVHSREGCYLYMKDVEKGSTDVLLGAEEKEAL
                     ERALGY"
     gene            complement(1698..2831)
                     /locus_tag="ACZPCR_11560"
     CDS             complement(1698..2831)
                     /locus_tag="ACZPCR_11560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003503719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HIR1231527.1"
                     /translation="MARRGLGKGLRAYFPDYQEENSHSELEHEVSEQDGSHGEDEHSV
                     DRKAKLEELDMVLPGSSRKAKADSDKKKAKKTGTAAGQKAAGKNTSKPSAKSGEKTEK
                     GKTAGAGQKEEGAREQLLNIAQIEPNQEQPRKHFNEEQLKELAESVKNYGILQPLLVQ
                     KKGDFFEIIAGERRWRAAKLAGLKEVPVLIRDYTKQQTVEIALIENVQRADLNPIEEA
                     KAYQMLVQEFGLKQEEVAERVSKNRATITNSMRLLKLDERVQNMLIENQLSGGHARAL
                     LALEDREQQYALAVKVRDNQLSVRETERLVKLAAAPKKEKKEQERDLSFIYRDLEEKL
                     KSIMGTKVTINKKDKNKGRIEIEYYSSAELERLIELLQSIHEA"
     gene            complement(2835..3602)
                     /locus_tag="ACZPCR_11565"
     CDS             complement(2835..3602)
                     /locus_tag="ACZPCR_11565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007862599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HIR1231528.1"
                     /translation="MGRVIAIANQKGGVGKTTTAINLSACLAEAGQKVLAIDFDPQGN
                     ATTGLGLEKEYMEETVYEMMLGECTLEDCLHQEVQENLDVLPSDSNLAGAEIELLDLD
                     KKEFILKEHLDAVRDNYDFIMIDCPPSLSLLTLNALTAADTVLVPIQCEYYALEGLSQ
                     VLRTIGLVKKTMNPGLELEGVVFTMYDARTNLSLEVVENVKSNLNETIYKTIIPRNVR
                     LAEAPSHGMPINLYDSKSTGAESYRLLAAEVISRGED"
     gene            4152..5102
                     /locus_tag="ACZPCR_11570"
     CDS             4152..5102
                     /locus_tag="ACZPCR_11570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007862601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HIR1231529.1"
                     /translation="MNTKNKILTLTTLTSAAAAFTALLNKYIKHSASSKNFLGSSQAH
                     IFKWRFGQVYYTKEGSGKPLLLIHDFHLAASGYEWHLAVKLLKKHYTVYTIDLLGFGR
                     SEKPNLTYTNYLYVQLLSDFIRTEIGHRTSAVTTGSSASIAVMACSINPDLFDKLAFI
                     NPDPFSVCSQFCGKNAKLYKFILDLPIIGTLLYHIASSRELLTQKFVQDFFSSPSALK
                     PAWIDAYYEAAHLGECPKAVFASAECCYTRCNIVPALRKIDNSIYILGGAQEPNIKRI
                     IQEYREINPAVEYALISRAKHLPQLEQPEQLVKQLLILLD"
BASE COUNT         1315 a         1444 c          980 g         1599 t
ORIGIN      
        1 aaaatccccc ctaaaagatc ccttattctt tgagagctta tcgctttcct ttgtaacctt
       61 ttttatcagc aggaatgcag gaaacggtgt gccttcccac atcccacgca aaaaacaacg
      121 ctgcctctca tctgatatat ttagaaaaag ccggaacagg tttgatcctc tgtcccggct
      181 tttccagatt tctattcatt ttttatccta acgcttcgtc aaagaatact cttccctgca
      241 tccagacttt tcccttaaaa cggcggccta ctttcggttc tccgaacaaa tctgccttat
      301 taatgcacac tcgaaaatga atgtcattgc actccagctt catgtcgtaa agctcttcgc
      361 ctgtaattcg gtttttcttg agaagaatct cttctatttc tccaataatc gaatactgat
      421 cgcattctat cccgcttggc ataaaacagg tatcaataat ggtatacaga tcctccttcg
      481 ctgcccttct ggaagcctga gaatataagt caatatcttc gattgtcaag gattccattg
      541 cctctggatc tccgtttttc gcagcttcca gcagattatt tcgatttctg gacgccacct
      601 tggccattgc aatctgattt gccgtttttt tcacaggaag caagattttt ccgtgaaccg
      661 aaaatcccgc taagttggac gataccacct ctgtgctttt tcttcgcttt aaaatccttt
      721 cgcgatattc catcccgttt gtcacataga aaatcagaga aatccctact cgatattcgt
      781 ctaaaagtcc cgcgtaggtc tccttctctg tgtgcctctg aatggagcat tcagctgtgg
      841 aggtctcaat actgctctcc aggtaaggat agtaatactc aatttccagt tcgttctgct
      901 cgttcatttc tccgcacatg gaaattccaa ttccatccgc aatttccgca cgaagctcat
      961 aaaagtccgt gtcccgatca atctgaatgc agcgggaatc cttcggctcc ttggacaggc
     1021 attttaaaag agccttaata tctcgatttt tctgatacat actgaagcca gcagcacgca
     1081 aatatttatg catcgtttct atctcctctt aacttatgct ccgcaatctc tggatagatt
     1141 ggaaccgcag cttttccctg gctgcttccg catttaatag cccagggctc tctccagagc
     1201 ctctttttcc tctgctccca gaagcacgtc cgtgctcccc ttctccacat ccttcatgta
     1261 gagataacag ccttcccggc tatgaacaga gttcaaaata aagccagaat tattgtcgtc
     1321 cagcagcgcg ataacgaagc tcagattgcc tcccatccct ttaaaggcat tatactttac
     1381 aattcctatt ttctggtagc tggctctcac ctgtctggac aaagatttca gctgatctct
     1441 gccctctttg tctgtggcct gtctgacagc cgcctcatcc atcagatcca gaataatgtc
     1501 ctccagggtc tctgcgtcct tgcctctcat gaacatatca tagcgccggt acaactttct
     1561 gtactgtgaa aaacatacca gcgtcagaat catcagaacc agggtaagcg ccgcaagacc
     1621 gataatcagg taggctggat caaaaagaag gttatttaac atactgtttt ccattgtctg
     1681 ctatcactcc tgactttcta agcttcgtga atcgactgaa gcagttcaat cagccgttcc
     1741 agttctgccg aagaataata ttcaatctct atcctgcctt tgttcttatc cttcttatta
     1801 atagtaactt ttgttcccat aatcgatttc agcttttcct ccaaatcccg gtaaataaag
     1861 ctcaaatccc gttcctgttc tttcttttct tttttaggcg ctgccgcaag ctttaccagg
     1921 cgctcggtct cccggacgct gagctggtta tctctaacct tgacggccaa agcatactgc
     1981 tgttccctgt cctcaagcgc cagcaaagct ctggcatggc cgccggaaag ctgattttca
     2041 atcagcatat tttgtacccg ctcatccagc tttaagagac gcatactgtt ggtaatggta
     2101 gctctgtttt ttgaaacccg ttcggccact tcctcctgct tcagcccaaa ttcctgaacc
     2161 agcatctggt aagctttcgc ctcctcgata gggttcaaat ctgcccgctg gacattttca
     2221 atcagagcaa tttccactgt ctgctgtttt gtatagtccc ggattaaaac aggaacctct
     2281 ttcaatcccg ccagtttagc ggcgcgccag cgccgctcgc cggcaataat ttcaaagaaa
     2341 tctccctttt tctgtaccag aagcggctga agaataccat aatttttcac tgactctgcc
     2401 agctctttca gctgctcctc attaaaatgc ttccgcggct gttcctgatt cggttcaatc
     2461 tgggcaatgt ttaaaagctg ctctctggct ccctcttctt tctgcccggc tcctgcagtt
     2521 ttccccttct ctgttttctc cccgctcttc gcactgggct tcgaagtatt ctttccagct
     2581 gccttctgcc ctgcggctgt tcccgttttt ttcgccttct ttttgtctga atctgctttc
     2641 gctttcctgg agcttccagg aagtaccata tccagctctt ccagttttgc ctttctgtct
     2701 acagaatgct cgtcttcccc atggctgcca tcctgctctg aaacttcgtg ttccagctca
     2761 gaatgggaat tttcttcctg atagtccggg aaataagctc tcagtccctt tccaagtcct
     2821 cttcttgcca ttctttaatc ttcccctctg ctgattactt ccgctgccag aagccgatag
     2881 ctttcagctc ctgttgactt actgtcatac aaattaattg gcatcccatg gctgggcgcc
     2941 tccgccagcc gcacatttct cggaataatc gttttataaa tcgtttcatt caggttgctc
     3001 ttaacatttt ccaccacttc cagagagagg ttggttctcg catcatacat agtaaataca
     3061 acgccttcca gctccagtcc cggattcatg gtttttttca ccaatccaat cgttctgagt
     3121 acctggctga gtccctccag cgcatagtac tcgcactgta tcggcaccaa tacggtatct
     3181 gctgccgtca gagcgtttaa tgtcaaaagg ctgagagacg gcgggcagtc gatcataata
     3241 aagtcgtaat tatcccgcac tgcatccaga tgctctttta atataaattc ctttttatcc
     3301 aaatctaaaa gctcaatttc agctcctgcc agattggaat cagatggaag cacatccaga
     3361 ttttcctgta cttcctggtg aagacaatcc tccagcgtac attcgcccag catcatttcg
     3421 tagactgtct cctccatata ttctttttcc aggcccagac cagttgtcgc atttccctgt
     3481 ggatcgaaat caatcgctaa aaccttctgt ccggcttcag ccaggcaggc cgataaattg
     3541 atcgctgtcg ttgtcttacc cacgccgccc ttctggttgg caatcgcaat cacacgtccc
     3601 atgatgactt cctttcctat aatcaatata aaatatggcc tgctgtttcc aacacggcca
     3661 agcattcatt tcattagtat aacacatctt tttgcctttt cctacaggaa atatccccaa
     3721 ttcctcataa atgtttcacg tgaaacttgt catccagctt ccgtattttt ttgttccaca
     3781 tttttttttc ggaaaataca gcgcaaatgc cagggcaata gaacctcgag actatcgcgt
     3841 ggttttccta atacaagccg acgcagcggc acaggtgaaa gcactggtaa aagactgcag
     3901 cggcagtcag gcggctgtca aatcaatata accattcgcc tggcacgctt ttttgtggta
     3961 taataagagc gcttagcgaa tataaaccgt gcctgtctgt caaaaggctc cgcgccgcgg
     4021 cgttaaattt ttcttaaatt aatcttgttt ttaacgggag gcattatatt ggactcatgt
     4081 ccgctatgcg gacatgagtc ccgcgatata aaaatacccc tttttcgcta tcattaaagg
     4141 aggctgacac cttgaacaca aaaaacaaaa ttctcacctt aactaccctg acctctgccg
     4201 ctgcggcttt tacagcgctg cttaacaaat atatcaagca ttctgcttca tccaaaaact
     4261 ttttaggcag ctcccaggcc catatcttta aatggagatt cggccaggta tactatacaa
     4321 aagaaggttc tggaaagccg cttctgctta tccacgattt ccacttagcc gccagcggct
     4381 atgagtggca tctggctgtg aaactattaa aaaaacatta tactgtatac actatagatt
     4441 tgctgggatt tggccgttct gaaaagccaa atctcactta cactaactat ctgtatgtgc
     4501 agcttctctc tgattttatt cggacagaaa ttggacaccg aaccagcgca gtgacaacag
     4561 gaagctctgc atccattgct gttatggcct gcagcatcaa tccggatctc ttcgataaac
     4621 tggcttttat taatccagat cctttttctg tctgcagcca attttgcgga aaaaatgcaa
     4681 agctttacaa gtttattctg gatcttccca ttataggcac gcttctatac catattgcct
     4741 ccagccggga attgctgacg cagaaatttg tacaggattt cttctcctct ccctcagcct
     4801 tgaagcctgc ctggatcgac gcctactacg aggcagcgca cctgggagaa tgccccaaag
     4861 ctgtcttcgc cagcgccgag tgctgctata cccgctgcaa cattgttcct gcgctgagaa
     4921 aaattgataa cagcatttat attttaggag gagcccagga gccaaatatc aaacgcatca
     4981 ttcaggagta ccgtgaaatc aatccagctg tcgagtacgc cctgatttcc agagcaaaac
     5041 acctcccaca attggaacag ccggaacagc tggtaaaaca gcttctcatt cttttggact
     5101 gactcagcga atgatgcgtt ctcagtgaac agtccctctt taaaaccgta ttctctcaga
     5161 atattgttcg ctgcacagca caagtttctc catcctgtaa gtctcttcat taaataaaaa
     5221 gcaggcagga aacgcaaagt gatatgctcc ctttatgaga gacagtgaaa aaacaaactg
     5281 tcatcatgaa gggagcaatt ctatgtcaca aaaaggtaaa ctaaacacag aagaaaaa
//
LOCUS       DBMDUW010000090         5326 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_5983_length_5326_cov_3.385837, whole genome shotgun sequence.
ACCESSION   DBMDUW010000090 DBMDUW010000000
VERSION     DBMDUW010000090.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 5326)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 5326)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5326
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5983_length_5326_cov_3.385837"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(19..411)
                     /locus_tag="ACZPCR_11575"
     CDS             complement(19..411)
                     /locus_tag="ACZPCR_11575"
                     /inference="COORDINATES: protein motif:HMM:NF013855.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family protein"
                     /protein_id="HIR1231530.1"
                     /translation="MKRKFSLEEILNVIKAYIETHGYPPTQRELAAKFCCSVSTINIY
                     LQEMLEDEKLETDHSIGACRAFQVAGMRMVDTRELEGAVKQLGDLLNHCRDMAAGKDA
                     DPIWGRDVEALEAVIGAVRITEERRKQE"
     gene            complement(395..601)
                     /locus_tag="ACZPCR_11580"
     CDS             complement(395..601)
                     /locus_tag="ACZPCR_11580"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231531.1"
                     /translation="MRQIYGKYYVEKETAGRFQILQETGRGYASIGCYFSPALAAEEI
                     ADQEHGEKWIRERIEEEMKGEAEV"
     gene            complement(610..1119)
                     /locus_tag="ACZPCR_11585"
     CDS             complement(610..1119)
                     /locus_tag="ACZPCR_11585"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231532.1"
                     /translation="MGRRKIPKSSREEINRISAEKQERILRHLSEAGALTIKKAAEDL
                     GLTHSDARNQFGNLRVKNAIDCVGRCKDGYLYTIHRDNAKSYREQLEEIQEDEAIWPE
                     TIARFRKRVAPGAVYYYRDEEGVRRRTKVTDTRCPHICLFDNGQAYSWADVIRCSRKG
                     THTLGEWPK"
     gene            complement(1076..1474)
                     /locus_tag="ACZPCR_11590"
     CDS             complement(1076..1474)
                     /locus_tag="ACZPCR_11590"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231533.1"
                     /translation="MSEARKKAVRARLRAGYTVEDFRKLFEMAEASSFLKGQNNRNWT
                     ATFDWLIADANMAKVLDGNYKDKPQSSAYSSAKDVETAAWNKHRDYYGRAKNRFHNCE
                     SHGYDYEDILDQMGGIYGQEKDTEEQPGGD"
     gene            complement(2104..2403)
                     /locus_tag="ACZPCR_11595"
     CDS             complement(2104..2403)
                     /locus_tag="ACZPCR_11595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009290776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase"
                     /protein_id="HIR1231534.1"
                     /translation="MKRLWSVFTDDMDHCYFTGSPYVERHHIFESRKGNKKKSEARGF
                     IIPLRPELHPNGASFQRTPENAGIDKMLKQMAQRYYESHYGSRDEFIKEFGRSYL"
     gene            complement(2400..2981)
                     /locus_tag="ACZPCR_11600"
     CDS             complement(2400..2981)
                     /locus_tag="ACZPCR_11600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231535.1"
                     /translation="MELKGQLKSISCDYFTGHTLITCETEAAAAPHLEKLQGVPLAIT
                     FKKFRKKRSLDANAYYWVLVAKLGDKLNLSKPHLHNILLRRYGQPEVIDGKMIYLVLP
                     DTDQGARKADEAETYHIKPTSEVKTGRNGERFRTYVMLRGSSTYNTEEMAHLIDGLVS
                     ECKEVGIETATPEELSRMLELYEANRKRKGKTE"
     gene            complement(2991..3812)
                     /locus_tag="ACZPCR_11605"
     CDS             complement(2991..3812)
                     /locus_tag="ACZPCR_11605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231536.1"
                     /translation="MEKKALEFRTLQAGEIDCRIATVTEKGVSLLLYKDARVDQNILD
                     ETVGPMNWQRAHSRDNANCTVSIWDGEKQQWISKEDTGTESYTEKEKGLASDSFKRAC
                     FNWGIGRELYTAPFIWIPAGNCRIQEKGDRSGKKWTCYDRFSVKEIGYDASRNICSLV
                     ILNDSQRGRLVFNLAHPETVDKMAPAPSRQEPEQPKEEPKVGKAHIQTLYNECGRTGL
                     HWRQITETYGVKEMKELTISQFQDAMEKFKRYPDKPDPNMHTEPPEQMEGLPWNE"
     gene            complement(3793..3987)
                     /locus_tag="ACZPCR_11610"
     CDS             complement(3793..3987)
                     /locus_tag="ACZPCR_11610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009242353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231537.1"
                     /translation="MYYKGMTGTPEEGHVVEGALAYDYALERCLKGTEEDREEFREML
                     VEWFYSGNWIEEEDDGEESA"
     gene            complement(3991..4164)
                     /locus_tag="ACZPCR_11615"
     CDS             complement(3991..4164)
                     /locus_tag="ACZPCR_11615"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231538.1"
                     /translation="MNRYRCSECGCYLDPGEGRLCEECLELKKSRALRRKQSLGVFQE
                     TENGQIRMRLKGA"
     gene            complement(4145..4336)
                     /locus_tag="ACZPCR_11620"
     CDS             complement(4145..4336)
                     /locus_tag="ACZPCR_11620"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231539.1"
                     /translation="MRNNNLMFAPENKGEEALMLMGRVEAVAAYIRKSQYIDREIIAD
                     MLGVVLEPAEEADHESVSL"
     gene            complement(4498..4671)
                     /locus_tag="ACZPCR_11625"
     CDS             complement(4498..4671)
                     /locus_tag="ACZPCR_11625"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231540.1"
                     /translation="MRKKDTVPEHPLRAAQRKNAALRDEVRFLHEALFFTEILAAGFF
                     GAFLAVLASVGWL"
     gene            complement(4668..4823)
                     /locus_tag="ACZPCR_11630"
     CDS             complement(4668..4823)
                     /locus_tag="ACZPCR_11630"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231541.1"
                     /translation="MKEATITNCIDIHGKEYRMEELSEEKRKQIAMLLSDRFMEMAGY
                     RRKVCDE"
     gene            5032..>5326
                     /locus_tag="ACZPCR_11635"
     CDS             5032..>5326
                     /locus_tag="ACZPCR_11635"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231542.1"
                     /translation="MSEIDKTIQAFTASQKMIERMTSNAFSPIVNQQSTLLNTATASI
                     RFSNTFSGQYTIPPGFFSDLEQYEKLSKAISSNIDLHRVTAQMANAFASPIEKI"
BASE COUNT         1079 a         1607 c         1062 g         1578 t
ORIGIN      
        1 cggattatct acttcctcct attcctgttt tcttcgttct tctgttatcc ttactgctcc
       61 tatcaccgcc tccagcgcct ccacgtccct gccccagatt ggatctgcgt ccttcccggc
      121 cgccatgtcc cggcagtggt tcagcaaatc acctaactgc tttacagcgc cctccagctc
      181 cctggtatcc accatgcgca tccctgcaac ctggaatgcc cggcaagctc ctatcgaatg
      241 atccgtctct aatttttcat cctccagcat ttcctgcagg tatatgttta ttgtcgacac
      301 agaacaacaa aattttgccg ccagttcccg ctgcgtcggc gggtagccgt gggtttctat
      361 gtatgccttt atcacattca aaatctcttc cagactaaac ttccgcttca cctttcattt
      421 cctcctcaat cctctcccgg atccatttct ccccgtgttc ctggtctgca atctcctccg
      481 ccgccagcgc cgggctgaaa taacagccaa tggatgcata gcccctcccc gtctcctgaa
      541 ggatctggaa ccggccagct gtctctttct caacataata tttcccgtaa atctgtctca
      601 tatttcctcc tacttcggcc attctcccag cgtgtgggtt cccttcctgc tgcaccgtat
      661 cacatccgcc cacgaatagg cctgcccgtt atcaaacagg cagatatggg ggcatctggt
      721 gtccgtcacc ttcgtcctcc ttcgcacgcc ttcctcgtcc cgatagtagt aaacggctcc
      781 cggagcaaca cgcttccgga accgcgctat ggtctccggc cagatagcct catcttcctg
      841 gatctcctcc agctgttccc ggtagctttt tgcattatcc ctgtgaatcg tgtacagata
      901 gccatcctta caccgtccca cgcagtcaat ggcgtttttg acgcgcaggt tcccaaattg
      961 gttcctggcg tcgctgtgag tcagtcccag gtcctctgcc gcctttttga tagtcagcgc
     1021 ccctgcttcg ctcagatgtc tgagaatcct ttcctgtttc tccgccgaga tgcggttaat
     1081 ctcctcccgg ctgctcttcg gtatctttct cctgcccata aatgcctccc atctgatcca
     1141 gaatatcctc gtagtcatat ccgtggcttt cgcagttgtg gaaacggttc tttgcccggc
     1201 catagtagtc cctgtgctta ttccaggcag cagtttccac gtcttttgcc gatgagtaag
     1261 cactgctttg aggcttgtct ttgtaattgc cgtccagaac cttggccata ttggcatccg
     1321 caatcagcca gtcgaaggtg gccgtccagt tccggttatt ttggcctttc aggaaactgc
     1381 tggcttcggc catctcaaac agcttcctaa aatcctccac ggtatagcca gcgcgcagtc
     1441 tggcacggac agccttcttt ctggcttccg acatctttac caggcgggga tacgacccgc
     1501 aaacggagtt gtataactct cgaatcgtgg caagctggtt agaaaaggcg tccgtctttt
     1561 ctggtagtac gtcagtacta ctcttttgtt gtttttgttt atttttatta tttattatgt
     1621 ctccgctttg tactacggaa tatacttcgg gttgtactac gggatatact tcgggttgta
     1681 ctttcaaatt gtaagtatat tccgtagtgt ttcttccgca taatgagata aggcgatacc
     1741 gccccgggat gccttttctc cctttctggt attctaccag ccctgcattc acaagccggt
     1801 ccctgctctc tgtcagggat gcttctcttg ctatctgcag ggacaccatc aagcggcggt
     1861 tatctacttg catccattcc ggccatccgg ctctgctgct caggtacaca agtttgtacc
     1921 acaaaagctg cgacagagtg gggagggaat gggtttcgag ccaccgctca aatccgttaa
     1981 tctctgctat ataattcaag gctctaccgc ctttcttttt aatgccgggg agatgaccgc
     2041 tccccggcag atgtatcacc aatggcattt gtttcgtgat atattactgc cataggaggt
     2101 ctgttacaaa taggagcggc cgaattcctt aatgaactcg tcccggctcc cgtaatgact
     2161 ctcatagtat ctctgagcca tctgctttaa catcttatct attcctgcat tctccggtgt
     2221 cctctggaag gaagcgccgt tgggatgcag ttccggccgc agagggatga taaagcccct
     2281 ggcttccgat ttcttcttat tccccttgcg gctttcaaaa atatgatgcc tctccacgta
     2341 agggctgcca gtgaaatagc agtgatccat atcgtccgta aatacgctcc aaagtctctt
     2401 cattccgttt ttcccttccg cttccggttc gcctcataga gttccagcat ccggctcaat
     2461 tcttccggag tggccgtctc aatgcctacc tccttgcact cggacaccaa tccgtcaatc
     2521 agatgcgcca tctcctccgt gttgtaggta ctggatccac ggagcatcac ataggtgcga
     2581 aaccgttccc cgtttcttcc tgtttttacc tctgacgtag gcttaatatg gtacgtctcc
     2641 gcctcatcag cctttctggc tccctgatcc gtgtccggaa gcaccaggta aatcatctta
     2701 ccgtcaatca cttccggctg gccgtaccgc cgaagcagga tattatgcag atgcggtttt
     2761 gacaggttca gcttatctcc cagttttgcg acaagcaccc agtaatacgc gttggcgtcc
     2821 aggctccgct tcttccgaaa ctttttaaat gtgatagcca gaggaacgcc ctgcagcttc
     2881 tccagatggg gagctgcagc cgcttccgtt tcacaggtaa tcagggtatg cccggtaaag
     2941 taatcacagg aaatgctttt caactgtcct ttcagttcca tccttttcac ctattcattc
     3001 cagggaagcc cttccatctg ctccggcggc tctgtgtgca tgttcggatc cggcttgtcc
     3061 ggataacgct taaatttctc catcgcatcc tggaactggg aaatggtcag ctccttcatc
     3121 tcttttactc cgtaggtctc tgtaatctgc ctccagtgca ggccggtccg gccgcattcg
     3181 ttatacaatg tctgaatatg ggcttttccc accttcggtt cttctttcgg ctgttctggt
     3241 tcctgacgcg aaggagccgg agccatcttg tccactgtct ccggatgagc caggttaaac
     3301 acgagcctcc ccctctggct gtcatttaaa atcaccagag agcagatatt cctggacgca
     3361 tcataaccga tttctttcac cgaaaaccga tcataacaag tccacttctt cccgctcctg
     3421 tctcccttct cctgaatccg gcagtttcca gccgggatcc aaataaatgg cgctgtatac
     3481 agttcccggc caatccccca gttaaagcag gcccgtttaa aggagtcgga ggcaagcccc
     3541 ttctcctttt ctgtatagct ttctgttcct gtgtcttctt tagaaatcca ctgctgcttc
     3601 tcgccatccc agatgctgac tgtgcagttg gcattgtctc tgctatgggc ccgctgccag
     3661 ttcatagggc ctacggtttc gtctaatatg ttctgatcca ctctggcgtc cttataaagc
     3721 agcagggaca ctcccttttc tgttaccgtg gcaatccggc agtcaatctc tcctgcctgc
     3781 agcgtgcgga attcaagcgc tttcttctcc atcgtcttcc tcctctatcc agttcccgga
     3841 ataaaaccat tccacaagca tctcgcggaa ctcttctcga tcttcctctg tccctttcaa
     3901 gcatcgttcc agtgcataat cataagccag ggctccctct accacatgcc cttcttccgg
     3961 tgtgcctgtc attcctttat agtacatgtc ttaggctcct tttaatctca tccttatctg
     4021 tccgttttcc gtctcctgga agacgcccag gctctgcttc ctccgcaaag cccggctttt
     4081 ctttaactcc aggcactcct cgcagagtct tccttcgccc ggatccaggt agcagccgca
     4141 ttcactacag cgataccgat tcatgatctg cctcctccgc aggctccaaa accacgccca
     4201 gcatatctgc aatgatttcc cgatctatgt actggctttt tctgatatag gccgccacag
     4261 cctccactct ccccatcagc ataagagcct cttcgccttt attttctggt gcaaacatta
     4321 aattattgtt tctcacttgc ttttcctcct tgatccggtt tataatttac ttgataatat
     4381 ttttctcatg ggcctgtccg gcggcaaccg gcgggccttt tcttttgaaa tccctacacg
     4441 ggtacatcct gctgtactcc agacaccggt tcctgtaccg gcaatccctg caatccacta
     4501 cagccacccg accgaagcca gaacggccag gaatgccccg aaaaagccgg ctgccagaat
     4561 ttctgtgaag aacagggcct cgtgaagaaa cctcacttca tcacgcagcg ccgcattttt
     4621 cctctgtgcc gcccggagcg ggtgctccgg gactgtatct ttctttctca ttcgtcacac
     4681 acctttcttc tgtatcctgc catctccata aagcgatccg acagcagcat ggctatctgc
     4741 tttcttttct cctctgacag ttcctccatc ctgtactctt ttccatgaat atcaatgcaa
     4801 tttgtaatgg ttgcttcttt catgctgttc tcctccttct ctgctaaatt ttatgcaaga
     4861 cgggttgtac aaattgaaat attgtagttt tctctcacct ccctacagta tctcctcgac
     4921 actctcatcg gaaatttctt ctcctgcacc ttgcttttct tatcccctcg ctttatactg
     4981 tgctcacagg ccccatcagg ccgagtacat taatgagagg attattacca tatgtccgaa
     5041 attgacaaaa cgatacaagc atttactgca agccaaaaaa tgattgaacg catgacctca
     5101 aatgcatttt ctcccatcgt aaatcagcaa agcacactat tgaatacagc tacagcatca
     5161 atccgttttt ctaatacatt ctctgggcaa tacacaatac cacctggatt tttttctgac
     5221 ttagagcaat atgaaaaatt gtccaaagca atatcttcca acattgattt gcatcgggtt
     5281 acagcacaga tggctaatgc atttgcttct cccatagaaa aaattt
//
LOCUS       DBMDUW010000091         5200 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_6129_length_5200_cov_3.222593, whole genome shotgun sequence.
ACCESSION   DBMDUW010000091 DBMDUW010000000
VERSION     DBMDUW010000091.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 5200)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 5200)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5200
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6129_length_5200_cov_3.222593"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            123..1031
                     /locus_tag="ACZPCR_11640"
     CDS             123..1031
                     /locus_tag="ACZPCR_11640"
                     /inference="COORDINATES: protein motif:HMM:NF015550.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0051276 - chromosome organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HIR1231543.1"
                     /translation="MARAPDPRAEQAEKLFREGKKLIEIAETLGVPEGTVRSWKNRYN
                     WDDKSNATLQNKKRNVAKKINTKNKAAEDAVNQVMENTDLTDKQRLFCVLYVRSFNAT
                     KAYQKAYRCSYETAMVEGWNTLRNPKIRDEISRLKQNRLNREMLDEHDIFQKYMDIAF
                     ADITDFVEFGREKVPVMGAFGPVEVKDPDTGEKVPLMQEINTIRFRDSSEVDGSLISE
                     VKQGKSGASVKLADRMKALEWLAAHMDLATEEQRAKISLMKLKAGGAEEEELPDDGFL
                     EALKGSAASDWEEMAGGTEHEKTSGI"
     gene            1009..2301
                     /locus_tag="ACZPCR_11645"
     CDS             1009..2301
                     /locus_tag="ACZPCR_11645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HIR1231544.1"
                     /translation="MKKRPVFKFQPFSRKQRMVLNWWTNKSPVKDYDGIIADGAIRSG
                     KTVSMSLSFVMWAMTSYNGQQFIMAGKTITSFRRNVLMGLMTMLRSRGYHCIHHLSGE
                     TPNMLEVSRKGRTNYFYIFGGKDEASQDLVQGVTAAGAFFDEVALMPESFVNQATGRC
                     SVEGAKLWFNCNPGAPLHWFKVRWIDELQKKRLLYLHFTMDDNLSLSEKTKEKYRNRY
                     VGVFFLRYIKGLWRVAEGLIYTAFTDENLYDEMSEKTRHLSSRVIAVDYGTTNPCVFL
                     DTYDDGQTIWVEREYRWDSRSEEAQRSGASQKTDKQYADDMAEFMGSRPEDQCPIIVD
                     PSAASFIQELRSRGWVVKPADNEVLDGIRKLSTMYARGAVKINRNQCKGLIAENQSYV
                     WDDKAAERGEEKPVKQQDHGPDALRYRINALPKWRIGA"
     gene            2303..2521
                     /locus_tag="ACZPCR_11650"
     CDS             2303..2521
                     /locus_tag="ACZPCR_11650"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231545.1"
                     /translation="MTKKKRTYQKKQGKITYYRCGDRECVEITPPIKTESMKLSPNIA
                     VQSDSEIDSSVLVEEIKKVLGQAIKEKR"
     gene            2525..3985
                     /locus_tag="ACZPCR_11655"
     CDS             2525..3985
                     /locus_tag="ACZPCR_11655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HIR1231546.1"
                     /translation="MARKRRTPRRAEKQNINTQAPVVTMDAFSNPAARIGWGTMDLMN
                     GTSYPMTRLTQNYELLTSMYRDNWIIQNIVATVPNDMIRKWYQVKSRITPKQLDQLIK
                     LERKTQLRKKLLLGMYWGRLYGGAVGVLLIKGQENMSEPLDFDLVMPGSFLGLQILDR
                     WSGVYPEGDLVQDPSDPDYGLPAFYTIRDDTTGHLAARVHHSRIVRFIGRELPWMEQV
                     AELYWGESEIEAIYNEVARRDNVASNIAALTFRANVNYMEAEGLDQLLGTANAEMQRR
                     FWNVMAAQAMMESNFGTRIINKGDAIHNTQYTFTGLPEVYDRVMMDVAGAARIPVTKL
                     FGRSPAGLNSTGESDMQNYYDYIDGLRENELRPVIERLLPVMALSAWGEVPDDLEIDF
                     PPMQTADAKEQAEITERNTNSILAAYQNDLIDAATAQQELQAMGEETGIFSRISDETI
                     EAARGQTYTKSRLMTDPMAGLEMARGLAGETGGEEW"
     gene            3989..>5200
                     /locus_tag="ACZPCR_11660"
     CDS             3989..>5200
                     /locus_tag="ACZPCR_11660"
                     /inference="COORDINATES: protein motif:HMM:NF017919.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor capsid protein"
                     /protein_id="HIR1231547.1"
                     /translation="MVQIRAIRPPKAKDLTLFLRTLFLRTERQIIDEITRKRAAGYVD
                     YAEVAALERVQRILQTMVDESWSYVPQMIEKIFYHSDKHAAGYANARALTASQTAVVQ
                     QLSNNLLGEILEASETAYQTAQEFFTIARLEADPYRKAALTQTVAQEALGTGWKQTSA
                     KMAAELRNQGLTGFVDKAGRKWTLSNYCNMATRTTARQAEVAAVLTADDYDLWQIVKI
                     GSTCPVCAPLEGRVYSKSGTNPDYPPLSLAFGKVDPDGGDDLTNTYLNIHPNCLHSLI
                     RYTMVGKTEKQIQRDKDFSDPKKNPLSRDPRTKKQIAAYREKERNRQKFLRDMKQHKE
                     YREILGNEIPKDFEKFQKMKYTEGERFELFRKKVENLEQARRFKEKLKNGSINTAVRN
                     VKQQEHIQGTKK"
BASE COUNT         1522 a         1036 c         1510 g         1132 t
ORIGIN      
        1 ttatagataa gattatatca gatttcccaa aagatggcga ttaaaagatt aataactaag
       61 aggtggatat agttgcctct ttttctatac gctaaaacga aacgaaggag aggtggtggt
      121 gtatggccag agcgccggat cccagagcag agcaggcgga aaagctgttc cgtgaaggaa
      181 agaaactgat agagattgcg gagactttgg gtgtcccaga ggggacggtt cgaagctgga
      241 aaaacaggta taactgggat gataaatcaa atgcaacgtt gcaaaacaag aaacgcaacg
      301 ttgcgaaaaa aataaataca aaaaataaag ctgctgagga tgcagttaat caggtaatgg
      361 aaaacactga tttaactgat aaacagcggc ttttttgtgt cctgtatgtt cgcagcttta
      421 atgctacaaa ggcgtatcag aaagcgtaca gatgcagtta tgaaaccgcg atggtggaag
      481 gctggaatac cctaagaaac cctaagatcc gagacgagat ttcccgcctg aagcagaacc
      541 gtctgaaccg ggaaatgctg gatgaacacg atatcttcca gaagtacatg gacattgcct
      601 ttgcggatat tacggacttc gtggagttcg gacgggaaaa agttccggtt atgggagcgt
      661 tcgggccggt agaggtaaag gatccagata caggtgaaaa agtgcctctg atgcaggaga
      721 ttaataccat ccggttccgg gattcctcag aggtggacgg ttccctgatt tctgaggtga
      781 aacagggaaa aagcggagcc agtgtaaaac tggcagaccg catgaaggct ctggagtggc
      841 tggcagctca tatggatctt gcgacggagg aacagagagc caaaatttcc ttgatgaagt
      901 taaaagcagg cggagctgag gaagaggagc ttccggatga tggtttcctg gaagcgctga
      961 aaggttctgc tgccagtgat tgggaagaga tggcaggggg aacggaacat gaaaaaacgt
     1021 ccggtattta agttccagcc tttttcgaga aagcagcgca tggtgctcaa ctggtggacg
     1081 aataagagcc ctgtgaaaga ctatgacggc atcattgcag acggggcgat ccgttccgga
     1141 aaaacggtat ccatgtccct gtcgtttgtg atgtgggcga tgactagcta taacggccag
     1201 cagtttatta tggctggaaa gactatcaca tccttccgca gaaatgtact tatgggactt
     1261 atgacgatgc ttagaagccg cggttatcac tgtattcacc atctgtcggg ggaaaccccg
     1321 aacatgctgg aagtgtcccg taaaggcaga accaactact tctacatatt cggaggaaag
     1381 gatgaggcct ctcaggacct ggtacagggt gtaacagctg ccggcgcatt cttcgatgag
     1441 gtggcattaa tgccggaaag ttttgtgaat caggccactg ggcgatgttc agtggaaggg
     1501 gcaaagctgt ggtttaactg caatccagga gcaccccttc attggtttaa ggttcgatgg
     1561 attgatgaac tgcagaagaa aagactttta tacctgcact tcacaatgga cgataaccta
     1621 agtttgtcgg agaaaacgaa agaaaagtac aggaaccggt atgtgggtgt attcttcctg
     1681 cgctacatta aaggattgtg gagagtggcg gaaggactga tttacactgc ctttacggat
     1741 gagaatttat atgacgaaat gagtgaaaag accaggcatt tgtcgtcccg tgtgattgct
     1801 gtggactatg gaaccacgaa tccctgcgtg tttctggata cttatgacga tggccagact
     1861 atctgggtgg aacgggagta ccgctgggac agccgttcag aggaggcgca gcgttcgggg
     1921 gcttcccaga aaacggacaa gcagtatgcg gacgatatgg cagagtttat gggcagcagg
     1981 ccagaagacc aatgtccgat cattgtggat ccgtcggcag cttcgttcat tcaggaactg
     2041 cgttcgcggg ggtgggtggt aaagccggcg gataatgagg ttctggatgg gatccgaaaa
     2101 ctgtctacga tgtacgcccg cggggcggtt aagataaaca ggaatcagtg caaaggcctg
     2161 attgctgaga atcagtctta tgtgtgggat gacaaggcgg ctgaacgggg agaggagaag
     2221 ccggtcaagc agcaggatca tggaccggat gctcttcgct accgaattaa tgcgctgccg
     2281 aaatggagga taggagcata acatgacaaa gaagaaaagg acatatcaga aaaaacaagg
     2341 aaagattaca tattatcgtt gtggtgacag agaatgcgtc gagataactc cacctataaa
     2401 aacagaaagt atgaaactga gtcctaatat tgctgtgcaa agcgattctg aaatcgattc
     2461 ttctgtactg gtcgaggaaa ttaaaaaagt gttaggacag gcaattaaag aaaagagata
     2521 aattatggca agaaaaagac gaaccccaag gcgggcagaa aaacagaata taaatacaca
     2581 ggcgcctgtc gttacgatgg acgccttttc taatcctgct gcccggattg gatgggggac
     2641 gatggacctg atgaacggca catcctatcc catgacccgg ctgacgcaga attatgagct
     2701 tcttaccagc atgtatcgtg ataactggat cattcaaaat atcgtggcaa cggttccaaa
     2761 cgatatgatc cgaaaatggt atcaggttaa aagcagaatt accccgaaac agttagacca
     2821 gctgataaag ctggaacgca aaacgcagct gagaaaaaaa ctgcttttag gtatgtactg
     2881 gggccggctg tatggcggcg ctgtaggagt gctgttaatc aaagggcagg aaaatatgag
     2941 tgaacctttg gactttgacc tggttatgcc gggcagcttc ctgggactgc agattctgga
     3001 tcgctggtct ggtgtttatc cggaggggga tctggtgcag gatccgtctg atccggatta
     3061 tggactgccg gccttttaca cgatccggga tgacacaacc gggcatctgg cggcaagagt
     3121 tcatcacagc cgcattgttc gattcattgg ccgggagctt ccctggatgg aacaggtggc
     3181 agagctttac tggggagagt cagagattga ggccatttat aacgaggtgg cgcgccggga
     3241 caacgtagct tccaatattg cagcactaac ctttcgtgct aatgtgaatt acatggaagc
     3301 ggaagggctt gatcaactgc ttggaacggc taacgcggag atgcagcgcc gtttctggaa
     3361 tgtgatggcc gcccaggcta tgatggagag caattttggc acgagaatta ttaacaaggg
     3421 ggatgcgatt cacaatactc agtatacgtt tacagggctt ccagaggttt atgaccgggt
     3481 gatgatggat gtggctggag ctgcccggat cccggtaacg aagctgtttg ggcgttcgcc
     3541 ggcagggctt aattccactg gggaaagtga catgcagaat tattacgatt acatcgacgg
     3601 cctgcgggag aacgagctga ggcctgtgat tgagcgcctt cttccagtga tggctctatc
     3661 tgcctgggga gaagttccgg atgacctgga gattgatttt ccgccgatgc agacagctga
     3721 tgcaaaggaa caggccgaaa ttacggagcg gaacacaaat tctatcctgg ctgcatacca
     3781 gaatgacctg attgacgccg ccactgccca gcaggagctt caggcgatgg gagaggaaac
     3841 aggaattttc agtcgaatct ccgatgaaac cattgaagca gccaggggac agacctatac
     3901 gaaaagcagg ctgatgacgg acccgatggc tggtctggaa atggccaggg gattggcagg
     3961 ggagactggc ggggaggaat ggtaaagtat ggtacagatt cgggcaatcc ggccaccgaa
     4021 agcgaaagac ctgactttgt ttttgcggac tcttttcttg aggacagagc ggcagattat
     4081 tgatgagatc acccgtaagc gggcggcagg gtatgtagac tatgcagaag tcgcggctct
     4141 ggaacgagtt cagaggatcc tacagacaat ggtagatgaa tcctggagct atgtgccgca
     4201 gatgatagaa aagatttttt accattctga taagcatgcc gccggatatg ccaatgccag
     4261 ggctctcaca gcatcgcaga cagcagtggt gcagcagctc tctaacaatc ttctggggga
     4321 gattctggag gcatcagaga cagcttatca aacggcgcag gagtttttta cgattgcaag
     4381 attggaggcg gatccgtaca gaaaggcagc gctgacgcaa acagtagctc aggaggcgtt
     4441 aggaaccggc tggaagcaga ccagcgcaaa gatggcggca gagcttagaa atcagggtct
     4501 cactggtttc gtagataagg caggaagaaa atggacgctg tctaattact gtaatatggc
     4561 cacgcgtacc acagccaggc aggcggaggt ggcggctgta ctgactgccg atgattacga
     4621 tttgtggcag attgtaaaaa tcgggagtac ctgtccggta tgcgctccgc tggaaggccg
     4681 ggtatactca aagagcggaa ctaatccaga ctatccgccg ctgtctctag cgtttgggaa
     4741 ggtggatccg gatggagggg acgacctgac gaatacttac ctaaatatcc atccaaactg
     4801 ccttcacagc ctgattcgct acactatggt tggaaagacg gaaaagcaga ttcagcggga
     4861 taaggatttc tccgatccga aaaagaatcc attaagccgg gatccgcgaa cgaaaaaaca
     4921 gattgcggcc taccgggaga aggaacggaa ccggcagaag tttctgaggg acatgaagca
     4981 gcataaagaa taccgcgaaa ttttaggaaa cgagataccg aaagattttg aaaagttcca
     5041 aaaaatgaag tatactgaag gtgaaaggtt tgagctattt agaaagaaag ttgaaaatct
     5101 ggagcaggcc cgaagattca aagaaaaatt aaaaaatggc tcaatcaaca cagctgtaag
     5161 aaatgtgaaa cagcaggaac atattcaggg aactaaaaag
//
LOCUS       DBMDUW010000092         5067 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_6312_length_5067_cov_5.461740, whole genome shotgun sequence.
ACCESSION   DBMDUW010000092 DBMDUW010000000
VERSION     DBMDUW010000092.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 5067)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 5067)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5067
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6312_length_5067_cov_5.461740"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..333
                     /locus_tag="ACZPCR_11665"
     CDS             <1..333
                     /locus_tag="ACZPCR_11665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008705918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231548.1"
                     /translation="FLLKSRAEVVAMSIFEYDEERERELIKKAEFESGKEEGIKAGIE
                     LGKAQGIELGKAQGIELGKIQGIAALIHAFRDLGASREAALLSLKKQFSLSEEEAERQ
                     LEQLWPMA"
     gene            687..1205
                     /locus_tag="ACZPCR_11670"
     CDS             687..1205
                     /locus_tag="ACZPCR_11670"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002589467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HIR1231549.1"
                     /translation="MQNPVITIEMESGDVIKAELYPEIAPNTVNNFISLVKKGFYDGL
                     IFHRVIRGFMIQGGCPDGNGTGGPGYSIKGEFARNGFKNDLKHTPGVLSMARAMHPDS
                     AGSQFFIMHETSPHLDGEYAAFGHVTEGMDVVNKIAECRTDWSDRPMKAQKMKKVTVE
                     TFGEDYPEPEKC"
     gene            1199..1909
                     /locus_tag="ACZPCR_11675"
     CDS             1199..1909
                     /locus_tag="ACZPCR_11675"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1231550.1"
                     /translation="MLIEREIEVNGSLFQAVISDDRQALQAAYAAGRAVVGLWQRKAE
                     KEREEGGAAERSETEEIPDLFPALYLVERLEDADEELLKKAVCRRFSMPWTIAETKRL
                     LIREFKASDALPDEEEEFRTPELLSSYIACQYRFYESGLWALVEKATGKIVGKAGITD
                     GELGYHIYKEYRRRGLAEEACRAIIRREKEEGRTCVRLQARADNMASRRLAEKLGFVQ
                     AEEEICSIGSCILYVLSI"
     gene            1983..2912
                     /gene="ispE"
                     /locus_tag="ACZPCR_11680"
     CDS             1983..2912
                     /gene="ispE"
                     /locus_tag="ACZPCR_11680"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HIR1231551.1"
                     /translation="MIKHLGLKAYGKVNLGLDVVRRREDGYHEVRMIMQTVGIYDRID
                     LMRREQPGIGIETNLYYLPDNENNLAYKAARLLMDEFDIKEGVNIRIKKFIPVAAGMA
                     GGSSDAAAVLFGVNKMFSLGLSMEELMKRGVRLGADVPYCLMRGTALSEGIGEILTPL
                     DPVPQCQVLIAKPSVSVSTKFVYENLHVNQLPKTAHPDIDRLMRAIEDRDLRGLAENM
                     GNILETVTIPAHPVIQDIKDKMMAMGAVGAMMSGSGPTVFGLFMSPARAEEAYEEMRY
                     GSAASMARQVYLTRFYNRNKDADIRQGNERNGK"
     gene            2902..3585
                     /locus_tag="ACZPCR_11685"
     CDS             2902..3585
                     /locus_tag="ACZPCR_11685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HIR1231552.1"
                     /translation="MGNNFQVNMNEYLPLRDVVFNTLRQAILKGELAPGERLMEIQLA
                     EKLGVSRTPIREAIRKLELEGLVLMIPRKGAEVARISEKSMRDVLEVRRSLEELAIEL
                     ACERMTEEDFKELDLAQNAFKKAVAGGTAMEIAETDEAYHDIIYNSTGNTRLVQILNN
                     LREQMYRYRLEYIKDEEKRQILLAEHRKIYRALCSRHVEEAKQAMREHIDNQEITVLK
                     NIKEQENDF"
     gene            3575..4795
                     /locus_tag="ACZPCR_11690"
     CDS             3575..4795
                     /locus_tag="ACZPCR_11690"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008396599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HIR1231553.1"
                     /translation="MTFKELYLSGQIEFDEIDRYISRWNRSDDERTLAKYLGLNAEEE
                     DVWIDDSDEALQDLLDSYERVKGTPVTLGRTGIIVNKNGFGALPIQRIGKEEAAVLLK
                     KAYDGGIRYFDTARAYSDSEEKIGYALKDVRSHIYIATKTMASTPEKFWEDLETSLRL
                     LQTDYIDVYQLHNPPVCPKPGDETGLYDAMLEAKKQGKIRFIGITNHRIDVAEEAVES
                     GLYDTLQFPFNYLSTERERALAEKCREKDMGFIAMKGLSGGLLTNSAAVYAYMARYEN
                     VLPIWGIQKEKELDEFLSYIDQPPVLDETLQKVIDSDIETLAGDFCRGCGYCMPCPVG
                     IEINNCARMSLLLRRSPSAGHLSPEGQAKMKKIEDCLHCGACKSKCPYGLDTPKLLEE
                     NYKDYMEVLARKEM"
BASE COUNT         1375 a         1095 c         1510 g         1087 t
ORIGIN      
        1 tttcttttaa aatcacgggc ggaggtagta gctatgagca tttttgaata tgatgaagaa
       61 cgggaacggg agctgattaa aaaggcggag tttgaatccg ggaaggaaga gggaatcaaa
      121 gctggaatcg aattaggtaa agcgcagggc attgaattag gcaaagctca gggcattgag
      181 ctgggtaaaa tccagggtat cgcagcctta attcacgctt tccgggatct gggcgcttcc
      241 agggaagctg ctcttctttc tctgaaaaag cagttttccc tctctgaaga ggaggctgaa
      301 aggcagctgg aacaactctg gcctatggca tagcagggct gttaaaggga tattccttct
      361 acgtggcccg ggttcgttcc tacgcctcgc agatggatat gaacgcagca gtcaaccgga
      421 cagtggaggc ctgaatcaga aaaccaggcc taatcagagt agaaaaggaa ttttccggta
      481 ccttttaatt ggaacgagga aaatttcttt tcttctctat gctgtctctc ttcagctttt
      541 gcagcttttg gtggtctttt gccggcctta catgttaatt cttgcaatcc gccgccacat
      601 ttgatacact tgtatcagac tggccgggac acggcctggt gccgtctgat gcaggcggcg
      661 caatgaatac tcaggaggat atcacgatgc agaatccagt tattaccatt gagatggaaa
      721 gcggggacgt aatcaaggca gagctctacc cggagattgc cccgaacaca gtaaataact
      781 ttatcagcct tgtaaagaag ggcttctatg acggacttat tttccaccgc gtgatccgcg
      841 gctttatgat ccagggcggc tgcccggatg gaaatggaac cggaggcccg ggctattcca
      901 tcaagggaga gtttgcccgc aacggcttta agaatgattt aaagcatact ccaggcgtgc
      961 tttctatggc cagagccatg catccagatt ccgcaggttc tcagttcttc attatgcacg
     1021 agacttctcc gcatttagac ggcgagtatg cggcgttcgg ccatgtgaca gagggcatgg
     1081 atgtggtcaa taagattgcc gagtgcagaa ccgactggag cgaccgcccc atgaaggctc
     1141 agaagatgaa gaaggtgaca gtggagacct tcggagagga ttatccagaa ccagaaaaat
     1201 gctgattgaa agagagatag aggtaaacgg ctctctgttt caggcagtca tatcagatga
     1261 cagacaggct ctccaggccg catacgcggc agggagagcc gttgtcggct tatggcagag
     1321 gaaagcggaa aaagagagag aagagggcgg ggcggcagaa agaagtgaaa cagaggagat
     1381 tcccgatctc tttcctgctc tctacttggt ggagaggctg gaggacgcgg acgaagaact
     1441 tctgaaaaag gccgtgtgcc gccggttttc catgccctgg acgattgcgg agacgaaacg
     1501 ccttctgatc cgggagttta aggccagcga cgcgctgcct gacgaggagg aggaatttcg
     1561 gacgccagag cttctgtcct cctacattgc ctgccagtac cggttttatg agagcgggct
     1621 gtgggcgctg gtagagaagg ccacagggaa gattgtggga aaggcgggaa tcacagacgg
     1681 ggagctggga tatcatattt acaaagagta cagaagaaga gggctggcag aggaggcgtg
     1741 ccgggccatt atccggcggg aaaaggaaga gggcagaacc tgtgtgagac tgcaggccag
     1801 agcggacaat atggcttcca gaagactggc agaaaagctg ggattcgtac aggcagaaga
     1861 ggagatttgc tcaattggtt cttgtatttt atatgtactg agtatataat atattgtata
     1921 caaaaaaata caaaaataca aaattcagca gcaagataca gcctgagctg agagggaggt
     1981 ctatgataaa gcatctggga ctgaaagctt acggaaaggt gaacctgggc cttgacgtag
     2041 tgaggagaag agaggacggt tatcacgaag tcaggatgat tatgcagaca gtggggattt
     2101 acgaccggat tgaccttatg agacgggaac agccgggaat cgggattgag acgaatctct
     2161 actatctgcc tgacaatgag aacaatctgg cctacaaggc cgccaggctt ttgatggatg
     2221 agtttgatat caaagagggc gtaaatatcc gcattaaaaa gtttatccct gtggcggcgg
     2281 ggatggccgg cggcagttca gacgcggcgg cagtcctctt tggagtcaac aagatgtttt
     2341 ccctgggtct ttccatggag gaactgatga agcgcggcgt aaggctgggg gccgacgtgc
     2401 cctactgcct tatgagggga accgcgcttt cagaggggat tggagagatt ctgacgccgc
     2461 ttgatccggt gcctcagtgc caggttctga ttgccaagcc gtctgtcagc gtttccacaa
     2521 aatttgttta tgaaaacctg catgtcaatc agctgccaaa gacggctcat ccggatattg
     2581 accgcctgat gcgggccatt gaggacaggg atctcagggg actggctgaa aatatgggga
     2641 atattttgga gacagtgacg attccggccc atccggtgat tcaggatatc aaggacaaga
     2701 tgatggccat gggcgcggtg ggagccatga tgagcggaag cggccctacg gtgttcgggc
     2761 ttttcatgag tccggccagg gcggaggagg catacgagga aatgcgctac ggatccgctg
     2821 cttctatggc cagacaggtc tacctgactc gattttataa cagaaacaaa gacgcagaca
     2881 taagacaggg gaatgaaaga aatgggaaat aattttcagg taaatatgaa cgagtatctt
     2941 ccgctcagag acgtggtttt caacacgctg cgccaggcga ttttaaaggg ggagctggct
     3001 cctggggaga ggctgatgga gattcagctg gcggagaagc tgggcgtcag ccgcacgcct
     3061 atccgggagg caatccgcaa gctggagctg gagggcctgg tgcttatgat tcccagaaaa
     3121 ggggcggagg ttgccagaat ttctgagaag agtatgcggg acgtgctgga ggtacgccgt
     3181 tctctggagg agctggccat tgagctggcc tgcgagagga tgacggaaga ggactttaag
     3241 gagcttgatc tggctcagaa cgcattcaaa aaggcagtgg ccgggggaac tgccatggag
     3301 atcgcggaga cagacgaggc ctaccacgat attatttaca acagtacagg aaacacaagg
     3361 ctggtgcaga tcctgaacaa tctgcgggag cagatgtacc gctaccgcct ggaatacatc
     3421 aaggacgaag aaaaacgcca gattctcttg gcggagcaca gaaagatcta cagggctctc
     3481 tgctcccgcc atgtggagga ggccaaacag gccatgcggg aacacattga caatcaggaa
     3541 atcaccgtac tgaagaatat aaaggagcag gagaatgact tttaaggaat tatacctgtc
     3601 agggcagatt gaatttgatg aaattgaccg ctacatcagc cgctggaacc gctctgacga
     3661 cgagagaacc cttgcaaaat atctgggact gaacgccgag gaggaggacg tctggattga
     3721 tgacagcgac gaggcgctgc aggatctgtt agattcctat gagagggtga agggaacacc
     3781 ggttaccctg ggaagaacgg gaattattgt caataagaac ggctttggcg cccttcccat
     3841 tcagcggatt ggaaaggaag aggccgctgt ccttcttaaa aaggcctatg acggcggaat
     3901 cagatatttc gacacggcca gggcctattc agacagcgag gaaaagattg gatatgcgct
     3961 gaaggacgtg agaagccata tttatattgc cacaaagact atggcctcca cgccggagaa
     4021 gttctgggag gatctggaga ccagcctgcg gcttctgcag acggattaca tagatgtgta
     4081 ccagctccac aatccgccgg tctgcccgaa accgggagat gagactgggc tgtacgacgc
     4141 catgctggag gcaaagaaac agggaaaaat ccggtttatc ggcattacta accaccggat
     4201 cgacgtggcg gaggaagcgg tggagtcagg gctctacgat acgcttcagt tcccgttcaa
     4261 ctacctgtct accgagaggg agagggccct ggcagagaaa tgccgggaaa aggatatggg
     4321 atttattgcc atgaagggcc tttccggcgg tctgctgacc aactcggccg ccgtctacgc
     4381 ctatatggcc cggtatgaga atgtgcttcc tatctggggg attcagaagg aaaaggagct
     4441 ggatgaattt ttaagctata ttgaccagcc tccggttctg gacgagacgc ttcagaaggt
     4501 gatagattca gatatcgaga ctctggcagg cgatttctgc cgcggatgcg gctactgtat
     4561 gccctgcccg gtgggaatcg agatcaataa ctgcgccaga atgtctctgc ttctgcgccg
     4621 ctctccgtct gccggccatc tgtcgccgga aggccaggcc aagatgaaga aaatcgagga
     4681 ctgcctccac tgcggagcat gtaagagcaa atgtccttac ggcctcgaca caccgaagct
     4741 tttagaggaa aattataaag attacatgga agtcctggca agaaaagaaa tgtaagtaaa
     4801 tgaaaaaata gaggggaaga gttccttcgg ctttcagccg aaccgcagga acccttcccc
     4861 tcttagttta ttcatgccgc atatctgtga atacgaaaca tcctgaaaac aaaatgtaaa
     4921 acttttataa attctgtttt cacatcttga caaggtgaca gggtgtcact ataataagtg
     4981 acagcttgtc actagagcgg caggcgttat gagaagatga tgtatgaaag tatgaaaaga
     5041 gcagggggag cgttatgccg tcagagc
//
LOCUS       DBMDUW010000093         5005 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_6387_length_5005_cov_2.840946, whole genome shotgun sequence.
ACCESSION   DBMDUW010000093 DBMDUW010000000
VERSION     DBMDUW010000093.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 5005)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 5005)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5005
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6387_length_5005_cov_2.840946"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            29..1063
                     /locus_tag="ACZPCR_11695"
     CDS             29..1063
                     /locus_tag="ACZPCR_11695"
                     /inference="COORDINATES: protein motif:HMM:NF012512.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-aminocyclopropane-1-carboxylate
                     deaminase/D-cysteine desulfhydrase"
                     /protein_id="HIR1231554.1"
                     /translation="MLLSGTTICSSERIREFTTPLHRLNNISNDLGVNLYIKRDDMTG
                     VNLFGGNKVRKLEFLIGYAKEHGYDTVFTFGATQSNHAMETASMCNAQGLKSILYLVD
                     LTEQKEERPKANLLLDMILGAEVHIIPANGREEAEADLEAEELCRKQVEQMEKEGHKC
                     FVIPEGGANYIGSTGFINGYAEMLEQMEQLNEKPDYIFHATGTGGTLAGLAAGRALLE
                     SDASIYSVTVSPKELSHLEKVANIANESLRYIGSDKTVLPSDMHYELSYYGEGYEKPT
                     KEATEAIQYLARKEGIIVDPVYTGKAFSGMLDCIRSGKIPQGSTVVFWHTGGATGIFA
                     EPEIVGEIWK"
     gene            complement(1070..2110)
                     /locus_tag="ACZPCR_11700"
     CDS             complement(1070..2110)
                     /locus_tag="ACZPCR_11700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HIR1231555.1"
                     /translation="MEQELTLFDKLYCCYYQAVRQVLEESACTPVSKKRMEEICETAA
                     FRESALSILPQLTDRDGAWSCLLSKTEDSLFSSALGDKALKAPLSCLQKAWIASICQD
                     PRFLLFFTEEERDFIKADIPALYQEEDFYYYDRFQNGDPYSSAMYRKHFRTVLTGLSE
                     KQLLKLSYKGKNQLLTDLKVLPVRLQYSPKDDKFRLLCIRLRKGRKGLPYTLNMGKIL
                     ACSLAGTWQTDVDRDSAPEPPFTSPSLAVFSQKAAEPAVIEIDGRRNSLERCMLKFAD
                     YEKHTVYDEERAVYTCSIYYDIQDETELLIDLLSFGPVIRVLEPERLVQEIRERVNRQ
                     HRRLFGEVREAF"
     gene            complement(2136..3500)
                     /locus_tag="ACZPCR_11705"
     CDS             complement(2136..3500)
                     /locus_tag="ACZPCR_11705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008397868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing transcriptional factor"
                     /protein_id="HIR1231556.1"
                     /translation="MAQFQELIKNFDRIRDYMRQFYVYGFKVRGEFTEKSTRTYDNER
                     RRIESWLSGCISSDYTAKGKQISISADSRSISSNPLYSAWKSKSFTDNDLLLHFFVLH
                     YLMQHRKAEQTAEGGQTEQAVSGTHPGMTAGELADQISADFGCFFDSQTVRLKLKEYE
                     NLGLLSSVRHQKSVYYKLAQPMLFEQPEFHGLYKRLLTAVSFFSEAAPFGFIGNTILE
                     REYQTNSCFCFKHYFMVHTLEDGILYPILQAIHRGGCLEFENHSQRSGNITFIQGFPL
                     QIFASTKTGRRYACIYAVKERRFLNLRLDCIASVKQLGESLEEAAHFRTLLDKNRSLC
                     FGVSFGQKTVRTEEICMKLFVDEEREEHILERLYREGKGGEVLRIRKNEYLYSGVFFD
                     VNEMLSWVKSFTGRIMDIQSSSESSVIKVISDWKSMYRMYGEENETPGNKADMPLDID
                     VEDV"
     gene            3675..4907
                     /locus_tag="ACZPCR_11710"
     CDS             3675..4907
                     /locus_tag="ACZPCR_11710"
                     /EC_number="6.5.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008452 - RNA ligase activity [Evidence
                     IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RtcB family protein"
                     /protein_id="HIR1231557.1"
                     /translation="MFVISDKAWKSPIKIWLEKREDLEESCFEQACHLAELPFLHKWV
                     CLMPDTHAGKGMPIGGVIAAKQVLIPNAVGVDIGCGMAWVGMNIKTEEIRGIVTGNGS
                     LIQGMVGDILRNIPVGFAHHKTAMPCYTLDRAFDEFDKYEQNGELLGQLDAGYFQVGT
                     LGGGNHFIELQEDEEGYLSVMIHSGSRHMGKSVCDYFHQKARELNSRWYSQVPDEYRL
                     AFLPLDTKEGQQYLNWMQLSMDFAMENRAKMMLAVKAILEKWIGRYTDLELSFTEEIN
                     CYHNYAALENHYGENVWVHRKGAVRAREGELALIPGAMGSNSYVVRGKGNAESFCSSS
                     HGAGRRYSRKGAMNAFTCEDVINDLKKQQVILGKKNKSDVAEESRFAYKDIDEVMKNQ
                     SDLVEPVKKLHTIGVVKG"
BASE COUNT         1398 a         1049 c         1290 g         1268 t
ORIGIN      
        1 acagacggtg gcttcggcgg catatacgat gctactatct ggcacgacaa tctgctcatc
       61 ggaacgaatc agggaattta ctacaccact tcacagatta aacaatatca gcaatgatct
      121 gggtgtcaat ttatacatta agagagatga tatgacaggt gtgaatctgt ttgggggaaa
      181 taaagtcaga aagctggaat ttttaattgg atatgcaaaa gagcatggat atgatacggt
      241 atttaccttt ggggcaactc agtcgaacca tgctatggaa actgcatcca tgtgcaatgc
      301 gcagggcctg aaaagtattt tatatctggt cgatctgaca gagcagaagg aagagagacc
      361 gaaagcgaac cttctgctgg atatgatatt aggagctgaa gtgcatatta taccggcaaa
      421 tggaagagaa gaagcagagg cggatctgga agcagaggag ttatgcagaa aacaggttga
      481 acagatggag aaggaaggcc ataaatgttt tgtaattcca gaaggtgggg ctaattacat
      541 tggaagtaca ggtttcatca atggatatgc ggagatgctg gaacagatgg aacagttaaa
      601 tgaaaagcct gattatattt ttcatgccac aggaacaggc ggaacactgg ctggcctggc
      661 agcaggacgt gctcttcttg aatcagacgc atccatttac agtgtaacag ttagtccgaa
      721 agaattgagt catttagaga aagtggcaaa catcgcaaat gaaagcctgc gttatattgg
      781 aagtgataaa actgttcttc catcagatat gcactatgaa ttgtcttact atggtgaagg
      841 atatgagaag cctaccaaag aagcgacaga ggcaatacag tatctggcaa gaaaagaagg
      901 tattattgta gatccggtat atacaggaaa agcattttca ggaatgctgg actgtatcag
      961 aagcggaaaa attccgcagg gaagtacagt tgtattttgg catactggag gagcaacagg
     1021 aatctttgca gagccggaaa ttgtagggga aatctggaaa tagggaagcc taaaaagctt
     1081 ccctcacctc cccaaacagc cgcctgtgct gcctgttcac tctctcacgg atctcctgca
     1141 ccagccgctc aggttccagc acgcggatga caggaccgaa ggacagcaga tcgatgagaa
     1201 gttctgtttc atcctgaata tcgtagtaga tggagcaggt gtagacggct ctctcctcat
     1261 cgtaaactgt atgcttttca tagtcggcaa attttaacat gcaccgttcc agagaatttc
     1321 ttctgccgtc gatttcaatg acagccggtt cagcagcttt ctgggagaat acagccaggg
     1381 agggcgatgt gaaaggcggt tcgggcgcgc tgtccctgtc cacgtctgtc tgccatgtgc
     1441 cagccaggct gcaggccaga attttcccca tgttaagcgt atagggaagt ccttttcgcc
     1501 ctttgcgaag ccttatacag agcagacgga atttgtcgtc tttaggagag tattggaggc
     1561 ggacaggaag gacttttaaa tcagtcagca gctgattttt tcctttgtag gacagcttca
     1621 aaagctgttt ttcggagagt cctgtaagga cagttcgaaa atgcttccga tacatggcac
     1681 tggaataagg atctccgttt tgaaaccggt cgtaataata gaaatcttcc tcctgataca
     1741 gagcagggat atctgccttt ataaaatcgc gctcttcttc agtgaagaac agaagaaacc
     1801 ggggatcctg gcagatagag gcgatccagg ccttctgaag acaggagaga ggcgctttca
     1861 gagccttatc ccccagagca gaggaaaaaa ggctgtcttc tgtttttgac agaaggcagc
     1921 tccaggctcc gtctctgtct gtcagctgcg gcagaataga cagggcgctt tccctgaagg
     1981 cagctgtttc gcagatttcc tccatcctct ttttgctgac aggagtgcag gccgactctt
     2041 ctaatacctg tctgactgcc tgataataac agcagtacaa tttatcaaac agtgttaatt
     2101 cctgttccat ggagaacctc ctcctatgcg ttttcttaaa catcttcgac atctatatct
     2161 aaaggcatat ctgccttatt tcctggagtt tcattttctt ccccatacat ccgatacatg
     2221 ctcttccagt cagaaattac cttgataaca gagctttcac tggaagactg aatatccata
     2281 atccgtccgg tgaaggattt cacccaggac agcatttcgt tcacatcgaa gaagacaccg
     2341 ctgtacagat attcattttt ccggatgcga agcacttctc cgccttttcc ttcccggtag
     2401 agccgttcta aaatatgttc ctccctttct tcgtctacaa aaagcttcat acagatttct
     2461 tccgtccgaa cggttttttg tccaaaggat acgccaaagc ataaagaacg gtttttgtct
     2521 aacagagttc ggaagtgagc cgcttcttcc aggctttcac ccagctgctt tacactggca
     2581 atgcagtcca gcctcagatt aaggaagcgc cgctccttga ccgcatagat gcaggcataa
     2641 cgccgccctg tttttgtgct ggcgaaaatc tgcagaggga agccctggat gaaggtaatg
     2701 tttccacttc tctggctgtg attttcaaac tccagacagc cgccgcggtg aattgcctga
     2761 agaatcgggt ataaaatgcc gtcttccagg gtgtgaacca tgaaatagtg cttaaaacag
     2821 aagcaggagt tcgtctgata ctcccgttcc agaatggtat ttccaataaa accgaaggga
     2881 gctgcctctg aaaagaagga gactgctgtg agaagccgct tgtagagtcc gtgaaactca
     2941 ggctgttcaa agagcatggg ctgagccagc ttataataga cagatttctg atgcctgaca
     3001 gaggacagaa gccccaggtt ttcatattcc ttcagtttca ggcggacggt ctggctgtca
     3061 aagaagcagc caaaatctgc tgaaatttga tcggccagct ctccggcagt catgcctggg
     3121 tgggtaccgg aaacagcctg ttctgtctgg ccgccttcag cggtttgttc tgcttttctg
     3181 tgctgcatca gataatggag aacaaaaaaa tgcagcagta gatcgttgtc tgtaaagctt
     3241 tttgatttcc aggcgctgta aagaggatta gaagagatgg aacggctgtc ggcgctgatg
     3301 gagatctgct ttccctttgc agtgtaatct gaggaaatgc agccggacag ccagctttca
     3361 atccttcgcc tctcattgtc ataggttctg gtactctttt ctgtaaattc gcctctcact
     3421 ttaaagccat agacataaaa ctgccgcata tagtcgcgga tccggtcaaa atttttaatc
     3481 agctcctgaa actgtgccat ggctatcctc ctctttgtcc tttatacact gacgctatag
     3541 gtaaattata gcaaggccgc aacttttttt aaatgatcaa tcaggaaaaa tttactagaa
     3601 taggcattgt aacagacaga tattatcaat tgcgccgccc cgcagagggc gcttggaaag
     3661 gaagtggaac aggtatgttt gttatatcag ataaagcatg gaaaagcccg atcaaaatct
     3721 ggctggaaaa gagagaggat ctggaggaaa gctgttttga gcaggcctgc catctggcag
     3781 aacttccctt ccttcacaaa tgggtatgtt tgatgccgga tactcatgca ggaaagggaa
     3841 tgcccattgg aggtgtgatt gcagcgaagc aggtgttgat tcccaatgca gttggagtgg
     3901 atattggctg cggtatggcc tgggtgggaa tgaatataaa aacggaagag attcgtggaa
     3961 ttgtcaccgg aaacggaagc ctgattcagg gaatggtagg ggatatttta agaaatatac
     4021 cggtgggctt tgcacatcac aagactgcca tgccctgcta taccttggac agagcctttg
     4081 atgaatttga caaatatgag cagaacgggg agctgttagg acagctggat gccggatatt
     4141 ttcaggtggg aaccctggga ggcggaaatc attttattga gcttcaggag gatgaggaag
     4201 gatatctgag cgtgatgatt cactccggca gccgccatat gggaaagtca gtctgcgatt
     4261 attttcacca gaaagccagg gaactgaaca gcaggtggta cagccaggtt cccgacgagt
     4321 accggctggc ctttctgccc ctggatacga aggaggggca gcagtattta aactggatgc
     4381 agctttccat ggatttcgcc atggaaaaca gggcgaaaat gatgctggct gtaaaggcaa
     4441 ttctggagaa gtggattggc aggtatactg atttagaact gagctttaca gaggagatca
     4501 actgttacca taattatgcg gctcttgaga accactatgg ggagaatgtg tgggttcacc
     4561 gaaaaggcgc tgtcagagcc agggaaggag agctggccct gattccggga gcgatgggtt
     4621 ccaacagcta tgtggtaaga ggaaagggaa atgcagagtc tttctgttcc tcctctcacg
     4681 gagccggacg ccggtattcc agaaagggag ccatgaatgc gtttacctgt gaagatgtga
     4741 taaacgatct gaagaagcag caggttattc tgggaaagaa aaataaatcc gatgtggcag
     4801 aggagagccg ttttgcctac aaggatattg atgaggtcat gaaaaatcag tccgatttag
     4861 tagagccggt aaaaaagctt cacacgattg gtgtggtaaa gggataattt ccagcagccg
     4921 attcctcgaa aatcggaaga ttttctgata ggagcaggtt tagggttcat acagacggac
     4981 tctgcctgcc gggtgcaaga agaaa
//
LOCUS       DBMDUW010000094         4991 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_6404_length_4991_cov_3.035583, whole genome shotgun sequence.
ACCESSION   DBMDUW010000094 DBMDUW010000000
VERSION     DBMDUW010000094.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 4991)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 4991)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4991
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6404_length_4991_cov_3.035583"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(97..981)
                     /locus_tag="ACZPCR_11715"
     CDS             complement(97..981)
                     /locus_tag="ACZPCR_11715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006778948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HIR1231558.1"
                     /translation="MELLQLRYFLVAAKYEHMTKAAEVLRIAQPALSQSIKRLEQELG
                     VPLFDREKRNIRLNDAGRFLEQKLLPIMAALEELPAEIKKRDLMNQRTIYLNLLAATR
                     LVTDCIIAYKELHPEVIFRLVQDPAREHDDICISTAFPGEFKHEEDHLLLRERFFMAV
                     PADSAYASLRSVSLSMLQDEGFISLSNNRPIRRICDRFCLEAGFAPHTVCETDNPESV
                     RNLIAAGLGVGFWPEYSWGLLSSPQICLLPIAPAECCRDIVIRFRPRSEEMKTTTNFF
                     CFLMDYTREKIGGSSMNL"
     gene            1268..1789
                     /locus_tag="ACZPCR_11720"
     CDS             1268..1789
                     /locus_tag="ACZPCR_11720"
                     /EC_number="2.7.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0050145 - nucleoside monophosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidylate kinase-like family protein"
                     /protein_id="HIR1231559.1"
                     /translation="MSRKTVCIEREYGSNGRKIAEWLSKKTGVPLYDKKALTQVAEEN
                     HLAPEGTAEDENKIPAMHREAIKFLADKGSCIFVGTCAAGVLQGRDKNVNVFVKADME
                     SKIRWAMDSEKIDRQTAEEKIATMDKERCRMRDIYSVTECGDKVDYDLIITSSRFGIE
                     GTADMIRSCMARF"
     gene            1965..3368
                     /locus_tag="ACZPCR_11725"
     CDS             1965..3368
                     /locus_tag="ACZPCR_11725"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003524369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HIR1231560.1"
                     /translation="MEYSRKFPEIEYAEIQAPTASFPKGPVDLTDATMEKRRRNILKR
                     MEEKNLDTLLIYADREHGGNFGYLTGFEPRFEEAALALHQDGTAVLLLGNENMKMAAY
                     SRILADTVHVPYFSLPNQPMGNQKPLWQLIEDAGIRRGSRVGAVGWKLFTSRLEDNTQ
                     LFDLPNFLLEALKKAVGETGAVVNATGLFIHPKTGARIHNNANEIAHYEYGAALASCC
                     MMRMLDQIEEGKTEIELASFLASGGQPVNVQTICATGDRFTNAVVAPRNKTVSLGDKF
                     SSTLGFRGGLTSRSGYIARTEEDLPEQVRDYLEAVAKPYYRAALVWYETMGLGLSAER
                     LYHLIEEVLPRNVYGWTLNPGHYVSDEEWMASPFYEGSETVIESGMMFQMDIIPSVPG
                     YGGVSAEDGIAVADERLRKELEDIYPEVWKRIEKRRAYMEKELGICLKPEILPLSDTE
                     GYLRPFLLNRKKAFRKK"
     gene            complement(3391..4077)
                     /locus_tag="ACZPCR_11730"
     CDS             complement(3391..4077)
                     /locus_tag="ACZPCR_11730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009429369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3D domain-containing protein"
                     /protein_id="HIR1231561.1"
                     /translation="MIFTLLAAFSSLASGSSAGHLDFFDESGISGWFYETGRPGETAS
                     FSIRLTNAVTGEIVQEIPMTSSLSRPDLESRTGSGSTPGFYTSIDWNALGGGLYTASI
                     ISGGKTVGNSLSHYSGSKNSESGLPEGVSSVQNLGSFRITGYCACRKCSAGWGGRTSS
                     GAMAVSRRTVAVDPRVIPMGSRLLINGQVYVAEDTGGGVKGNHIDVYCDSHAQAKSLP
                     FQSAQVFLLR"
     gene            complement(4312..4767)
                     /locus_tag="ACZPCR_11735"
     CDS             complement(4312..4767)
                     /locus_tag="ACZPCR_11735"
                     /inference="COORDINATES: protein motif:HMM:NF018437.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3D domain-containing protein"
                     /protein_id="HIR1231562.1"
                     /translation="MKRRLSHKVSAVIFCAVCSLSASFVSLADEAAEAAGPAAEVTAF
                     VEAETPDVIQEGEFLGDFEITAYCGCQKCSKGNILTYSGTTPEEGHTISADLDVFPIG
                     TRLVIDGTVYTVEDTGSGVDGNHLDIYFDSHEKALDYGRQTEEVYAAES"
BASE COUNT         1410 a         1054 c         1305 g         1222 t
ORIGIN      
        1 actataacag ctttcccatg cgtccactgg gatggaaatc acccaatcag gtacttcagg
       61 aatatttaca atccgtgtaa caaatgtttg acaaacctac aaattcatgg aactaccgcc
      121 aattttttct cttgtgtaat ccatgagaaa gcagaaaaaa ttggtggtcg ttttcatctc
      181 ctcgcttctg gggcggaagc ggatcacgat atctctgcag cattccgccg gcgcgatggg
      241 aaggaggcag atctgcggag aggagagaag cccccaggaa tactctggcc agaagcctac
      301 gccaaggcct gccgcgatca ggttccggac ggattcggga ttgtccgtct cacagacggt
      361 gtgaggggcg aaacctgctt ccaggcagaa gcgatcgcag atacgccgga tggggcggtt
      421 gttggagaga ctgataaagc cttcgtcctg aagcatggac aggctgacag aacgcaggga
      481 agcgtaggcg gaatctgccg gaacagccat aaaaaagcgt tctctcagga gcaggtgatc
      541 ttcctcatgc ttgaattccc ctggaaatgc tgtggagata cagatatcgt cgtgctctct
      601 ggccggatcc tggaccagac ggaagatgac ctccgggtga agctccttgt aggcgataat
      661 gcagtctgtc accagtctgg tggcagccag cagattcagg tagatagtgc gctggttcat
      721 cagatccctc tttttgatct cagccggcag ctcttccagg gcggccatga tcggcagcag
      781 cttctgctcc agaaagcggc cggcgtcatt taagcgtata ttcctctttt cccggtcaaa
      841 gagagggacg cctaattcct gctccagccg cttgatggac tgggagaggg ccggctgggc
      901 aatccttaga acttcagcag cctttgtcat gtgctcatat ttggcggcta cgagaaaata
      961 tcgaagctga agcagttcca taaaatcaaa atcccctttc agaaattgtt aaaaaataga
     1021 aaatcctgtt ctccgtatca gaggcagatt tcactgtttt ctcttaatat tatactgtaa
     1081 aattgggaaa aagaaagaga aatgaggcaa tttataacat gaatgttatg aatcaataaa
     1141 aataaagtat tggatatcgt taaaaaaata acgtataata agggcataga taaggagaac
     1201 ccgtgaacgt ggaacgggaa aaggtttcag cctaaatgag ataacaatgg ttcaggagga
     1261 ttagggtatg tcaagaaaaa cagtttgtat tgagagagag tatggaagca acggacgtaa
     1321 aattgcagag tggctgtcta aaaagacagg agtcccgctc tatgataaaa aggctctgac
     1381 acaggtggca gaggaaaatc atctggctcc ggagggaaca gcagaggatg aaaataaaat
     1441 tcctgctatg cacagagaag ccatcaaatt tctggctgac aagggatcct gcatttttgt
     1501 gggaacctgc gcagccggtg tacttcaggg aagagataag aatgttaacg tctttgtaaa
     1561 ggctgatatg gaaagtaaaa tccgctgggc catggacagt gaaaaaatcg accgccagac
     1621 agcagaggaa aagattgcca ctatggataa ggaaagatgc agaatgcgtg atatttattc
     1681 tgtaacagag tgcggagata aggtggatta cgatctgatt attacaagtt cacgctttgg
     1741 aatcgaggga actgcagata tgattcgctc ctgcatggct cggttctagg aattatcaag
     1801 cctccctttt tatattcact atatgtgttt taatgttcag ggcctcccca gagatcttgc
     1861 ttttctctgc gggaggtttc tgcttgatgt tgggaaaatg ctgttgtatg ataggggtat
     1921 tcaaaagaag tgcgcagggg atctgtgcag gaaaggaaca ggttatggaa tacagcagaa
     1981 aatttccaga gattgaatat gcggagattc aggctccaac ggcctctttc ccaaaggggc
     2041 cggtagactt gacagacgcg actatggaga agcgccgaag aaatatttta aagcggatgg
     2101 aggaaaaaaa tctggatact cttttgatct atgcggatcg ggagcatgga ggaaatttcg
     2161 gatatctgac gggatttgag ccgaggtttg aggaagccgc cctggccctt caccaggatg
     2221 gaacggcggt tctcctcctt ggaaatgaaa atatgaagat ggcggcttac agcaggattt
     2281 tggcagatac tgtgcacgtt ccttattttt cccttcccaa tcagcccatg ggaaatcaga
     2341 aacctctctg gcagctgata gaggatgcgg gaatcaggcg gggaagccgg gtgggagccg
     2401 tcggctggaa gcttttcacc agccgcctgg aggacaatac ccagctgttt gatctgccga
     2461 attttcttct ggaggccttg aaaaaggcgg tgggggagac gggagctgtg gtcaatgcca
     2521 cagggctttt tatccacccg aagacaggcg ccagaattca caataacgcc aatgagatcg
     2581 ctcattatga gtacggggcg gctctggcct cctgctgcat gatgagaatg ctggatcaga
     2641 tagaagaagg aaagacggag atcgagctgg cctcgtttct ggcgtctgga ggacagccgg
     2701 tcaatgtgca gaccatctgc gccacaggag atcgttttac caatgctgtc gttgctccca
     2761 ggaacaagac agtttctctg ggagataaat tttcgtctac tctgggcttc cggggaggcc
     2821 tgacttcccg ttccggctat attgccagga cagaggagga tttaccggag caggtccggg
     2881 actatctgga agcggtggca aagccttatt accgggcggc gttagtctgg tatgaaacca
     2941 tggggctggg gctttcagca gagcggctgt accatctgat agaggaggtt ctgcccagaa
     3001 atgtttacgg ctggacgctg aatccaggcc actatgtgtc ggatgaggag tggatggctt
     3061 ctccatttta tgagggctca gaaactgtaa tagaaagcgg aatgatgttt caaatggata
     3121 ttattccgtc tgtgccggga tatggcggcg tcagcgcaga ggatggaatt gctgtggcag
     3181 acgaaaggct tagaaaagag ctggaggata tatacccaga ggtttggaag aggatagaga
     3241 agcgcagggc ctatatggaa aaggagcttg gaatctgcct gaaaccggag attcttcctc
     3301 tttctgacac agaaggctac ctgcgtccct tccttttaaa taggaagaag gccttccgga
     3361 aaaaataaaa acgggagctg gtttttccct ttaccgcagc agaaagacct gggcgctctg
     3421 gaagggaaga cttttcgcct gggcgtggga atcgcagtaa acgtcaatgt gatttccctt
     3481 tacgcctcct cccgtatcct ccgccacgta cacctggccg ttaatgagaa gacggcttcc
     3541 catggggata actctgggat cgactgccac agttcttctg gagacagcca tggctccgga
     3601 gctggtccgt ccgccccatc ctgcgctgca tttgcggcag gcgcagtagc cggtaatacg
     3661 aaaagagccc agattctgta cagaagaaac tccttcaggg agaccacttt cgctgttctt
     3721 gcttccggaa tagtgggaga gagaattgcc cactgttttg cctccgctta tgatggatgc
     3781 tgtatagaga ccgccgccca gagcattcca gtcgatggaa gtgtaaaaac cgggagtgct
     3841 gccgcttccg gtccggcttt ccagatccgg ccgggagagg gaagaggtca tgggaatttc
     3901 ctgaacgatt tctcctgtaa cggcgtttgt cagacggatg gaaaaagagg ctgtttctcc
     3961 aggacgtcct gtttcataga accatcctga gataccagat tcatcgaaaa aatcgagatg
     4021 ccctgcgctg cttccggaag caagagaaga aaaagcggcg agcagtgtaa aaatcatagt
     4081 gaaaaaacat aattttagtg tctgtttcat aaaaaacctt tcttaaattt cagatataga
     4141 ataagatatt aaaaaagaca gctgaaatat tacaaaaatt aataaatgta acacttttgt
     4201 aataaatatg gccgtaagac agtattatac acagaatcta ggatttgtca ataaaaagac
     4261 gaaaaaaaag actgtacctc ataataagat gcagtctttt gtatcataat attatgactc
     4321 agcggcgtag acttcttctg tctgacgtcc atagtcaagg gctttttcat gtgaatcaaa
     4381 gtaaatgtca agatgatttc catctacgcc ggatccagtg tcttccaccg tgtaaacggt
     4441 tccgtcaatc accagacgcg ttccaatggg aaatacatct aaatcagctg agatggtgtg
     4501 tccctcctct ggtgtagttc cggaataggt gagaatattt cctttcgagc acttctgaca
     4561 tccgcagtag gcagtaattt caaaatcgcc taagaattct ccctcctgta taacatccgg
     4621 ggtttcagct tcgacaaagg cggtcacttc tgcagctggt ccggctgcct cggcggcttc
     4681 atcagccaag gaaacgaaag atgcgcttag ggaacagaca gcgcagaaaa taactgcaga
     4741 taccttgtga ctgagtcttc tcttcatata gttcctcaca atcagaattt ttttaaataa
     4801 agatgattta tatattaaaa tctatttatt attatattac aaaaatgtta aatgtcaagt
     4861 taaagatcag agagacagaa atgaaagcgc tgtgatattg ggagccctgc aaaaacctca
     4921 aaaaattttt caaaatcagt tgacaaactt ctatagaagt aatatagtat caactgtaga
     4981 tgttagcact c
//
LOCUS       DBMDUW010000095         4678 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_6842_length_4678_cov_3.078217, whole genome shotgun sequence.
ACCESSION   DBMDUW010000095 DBMDUW010000000
VERSION     DBMDUW010000095.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 4678)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 4678)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4678
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6842_length_4678_cov_3.078217"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(116..2527)
                     /gene="leuS"
                     /locus_tag="ACZPCR_11740"
     CDS             complement(116..2527)
                     /gene="leuS"
                     /locus_tag="ACZPCR_11740"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008398812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HIR1231563.1"
                     /translation="MAQYNHTAIEKKWRENWEKNPINVNDGKKEKYYCLDMFPYPSGS
                     GLHVGHWRGYVISDVWSRYQLLRGKYVIHPMGWDAFGLPAENYAIKMGVHPAKSTAEN
                     IKNIKRQIGEIAAIYDWDMEVNTTDPNFYKWTQWIFVQMFKKGLAYEKEFPINWCPSC
                     KTGLANEEVVNGCCERCGTAVTKKNLRQWMLKITAYAERLLNDLDKLDWPEKVKKMQS
                     EWIGKSYGAEVDFPVEGREDKITVYTTRPDTLHGATFMVLAPEHALAKSLATDETREA
                     VEKYIFDASMKSNVDRLQDKEKTGVFTGSYAVNPLNGAKVPIWLSDYVLADYGTGAIM
                     CVPAHDDRDFEFATKFGIPIIQVIAKDGKEIENMTEAYTEASGTMINSGEWNGMESSV
                     LKKEAPEMIEKMGIGRKTVNYKLRDWVFSRQRYWGEPIPIIHCPKCGNVPVPEDQLPL
                     TLPEVDSYQPTGTGESPLAVIDEWVNTTCPCCGAPAKRETNTMPQWAGSSWYFLRYVD
                     SKNNEALVSKEKADKYLPVDMYIGGVEHAVLHLLYSRFYTKFLHDIGVVDFDEPFKKL
                     FNQGMITGKNGIKMSKSKGNVVSPDDLVRDYGCDSLRLYELFVGPPELDAEWDDRGIE
                     GVSRFLNRFYNLVMTSKDKDIKETKEMVKLRHKLVYDIEQRFEQFSLNTVISGFMEYN
                     NKFIELAKKEGGIDKETLKTFVTLLAPFAPHLGEELWRELGGTDSVFHSTWPECDTEA
                     MKDDEIEIAVQINGKTRGVVALPADVDKETALAAGKEAVKDKLTGNIVKEIYVPGKII
                     NIVCK"
     misc_binding    complement(2651..2981)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(3108..4085)
                     /locus_tag="ACZPCR_11745"
     CDS             complement(3108..4085)
                     /locus_tag="ACZPCR_11745"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231564.1"
                     /translation="MKERKLKPGKETILICLGTANLVLVAGGLFFLAGENRSLLRQVQ
                     ELQVKVSQMEGSVTDTVRGISSEIQRGQERADSFVDQFQVTVTSKDSLRAEVHVTADL
                     KEYREGEEVYFIWEGAEETVSLPAVRTEGTQFQAETEVSALTESGILKIYKKSGEEIK
                     GEILEHVSVKDACFLQMDCSGFLGWSSGTGKTEVELSPDVSLFTVSVPEDVYLTRAEV
                     QIYIGNEMIQAQNLLETEKTSGAEGDTAWMEGTDSIYTASWNMKLSPETGDRIDLRIV
                     AEDSNGTVYSAVAARGIVQEENGLLSITEEPSDQTLHIEPEGEKAWQRQ"
BASE COUNT         1089 a         1271 c          975 g         1343 t
ORIGIN      
        1 cattaaaaaa gattcgtcaa ccttcggttt tcatccactg ttcccagcca gaaaaacaaa
       61 aatttaaaaa gagcctaaac cctttgattt ataagggaaa aggctctttt gattattatt
      121 tgcagacaat gtttataatt tttccaggaa catagatttc ttttacgata tttcctgtca
      181 gtttgtcttt tactgcttct tttcctgctg ccagagcggt ttctttatcc acgtcggccg
      241 gaagagctac cacgcctctc gtctttccgt tgatctgcac ggcaatctca atctcgtcat
      301 ccttcatggc ctctgtatcg cactctggcc atgtgctgtg gaatacgctg tctgtgccgc
      361 ccagctctct ccagagctcc tcgcccagat gcggggcaaa cggcgccagc agggtgacga
      421 aggtctttaa ggtctcctta tcgattccgc cttccttctt tgccagctca atgaacttgt
      481 tattgtactc catgaatccg gaaataacag tatttaagct gaactgctca aatctctgct
      541 cgatgtcgta aaccagcttg tggcgcagct tcaccatttc cttcgtctct ttgatatctt
      601 tatccttgct tgtcataacc aggttgtaga aacggttcag gaatctggaa acgccctcga
      661 ttcctctgtc gtcccactca gcgtctaact ccggcgggcc tacgaaaagc tcgtaaagtc
      721 tcaaggagtc gcagccgtaa tcgcgcacca gatcatccgg agaaactaca ttgcccttgg
      781 acttgctcat cttgattccg ttctttccgg taatcattcc ctggttgaac agcttcttga
      841 acggctcgtc aaagtcaacc acgccgatat cgtggaggaa cttggtatag aagcgggagt
      901 acagaaggtg aagcaccgcg tgctctacac cgccgatgta catatcaacc ggaaggtatt
      961 tgtctgcttt ctccttggaa acaagagctt cgttgttctt gctgtccacg tagcggagga
     1021 aataccagga agaaccagcc cactgaggca tggtgttggt ctctctctta gccggagcgc
     1081 cgcagcatgg gcaggttgtg ttcacccact cgtcgatgac agccagcgga gactcacctg
     1141 taccagttgg ctggtagctg tctacctccg gcagcgtcag cggaagctga tcctcaggaa
     1201 ccggcacgtt tccgcacttc ggacagtgga taatcggaat cggctcgccc cagtatctct
     1261 ggcgggagaa tacccagtcg cgcagcttgt agttgacagt cttgcggcca atacccattt
     1321 tttcaatcat ctcaggagct tccttcttca ggacagaaga ctccattccg ttccactcgc
     1381 cggaattgat catggttccg cttgcctctg tgtaggcctc tgtcatgttc tcaatctctt
     1441 ttccgtcctt ggcgataacc tggataatcg gaatgccgaa cttggtggca aactcaaagt
     1501 cgcggtcatc gtgagccgga acacacataa tagcgcctgt accgtaatct gccagtacat
     1561 agtcggacag ccagatcgga acctttgctc catttaacgg gttcactgcg taggaaccgg
     1621 taaatactcc cgtcttttcc ttatcctgaa gacgatctac attggacttc atggaagcgt
     1681 cgaaaatgta cttctctact gcttctctcg tctcatcggt agccaggctc ttagccagag
     1741 cgtgctccgg agccagtacc ataaaggtag cgccgtgaag agtatccggt ctggtggtgt
     1801 agacagtgat cttgtcctct ctgccctcta ccgggaaatc tacctctgcg ccgtaggatt
     1861 ttccaatcca ctcgctctgc atttttttaa ccttctctgg ccagtctaac ttgtccagat
     1921 catttaacag gcgctctgca taagcggtaa tcttaagcat ccactggcgg aggttcttct
     1981 tcgtaacggc agttccgcag cgctcgcagc agccgttgac aacctcctcg ttggcaaggc
     2041 ctgtcttaca ggacggacac cagttaatgg ggaactcctt ctcataggca aggcccttct
     2101 tgaacatctg cacgaaaatc cactgcgtcc acttgtagaa gttcggatct gttgtattga
     2161 cctccatatc ccagtcataa attgcggcaa tctcgccgat ctggcgctta atgttcttga
     2221 tgttctcagc tgtagattta gccggatgaa cgcccatctt gattgcatag ttctctgccg
     2281 gaagtccgaa cgcatcccag cccatgggat gaatgacata ttttcctctg agaagctggt
     2341 agcggctcca aacgtcagaa attacgtagc ctctccagtg gcctacgtga agaccgcttc
     2401 cagacggata tgggaacata tccagacagt aatatttttc tttttttcca tcattgacat
     2461 tgatcgggtt cttttcccag ttttcccgcc actttttctc aatggcggta tggttgtact
     2521 gtgccatttt catttcctcc ttttgttata tacgcagaat ctggagaaac gagttgctgc
     2581 ataaggaagc attctgcttt ccagaatttc tctgaaataa aaaatgccct gcctctctct
     2641 gctgattctg catagagacg caaggcttat cctctcgcgc ggtaccactc tatttcatgc
     2701 cgtgggcatg ctcttatggg ggaaactgcc tgactgctgt cctgaatcat acggccaggc
     2761 gcagactcaa acggcatttt ctcctcaccg cataacgggc ggcttccggc tctgcctact
     2821 caggagggct ccgattatat tcatataaaa atcaaatctg tcggccttcc cttcagcagg
     2881 ctgctccaag gcgagttcaa acgcgctccc caactgcctc gcaccacacg gcagctctct
     2941 gatggttcct gcactctact attcctcttc ccagcattta ctgatggttc ttaatttaac
     3001 atacttgcag acggctgtca aggttctgcc aggcgatttc caggcgattt tccaggcaat
     3061 ttccgctgca tttccacagc cgccttatgg agcttgcata tcaaatctca ctgcctctgc
     3121 catgccttct caccttccgg ctcgatgtga agtgtctggt cagaaggctc ctctgtgata
     3181 gaaagaaggc cgttttcctc ctgcacaatc cctcgggccg caacagccga atagacggtt
     3241 ccattggagt cctcagcgac aatgcgaaga tcgatccggt cccctgtctc cggactcagc
     3301 ttcatgttcc aggaagccgt atagatacta tccgtgcctt ccatccaggc agtatctccc
     3361 tctgctccgc ttgtcttctc tgtttccaga agattctgcg cctgtatcat ctcatttcca
     3421 atataaatct gaacctccgc cctggttaaa taaacgtctt ctggcacact gactgtaaac
     3481 agtgagacgt ccggagaaag ctccacttct gtctttcctg tcccgctgct ccagcccagg
     3541 aatccggaac aatccatctg aagaaaacag gcatccttca ccgacacgtg ttctaagatc
     3601 tctcccttta tttcttcccc gctcttttta taaattttaa ggattcccga ctctgtcagg
     3661 gccgatacct ccgtctctgc ctgaaactgc gtgccttccg tccggactgc cggaagactg
     3721 acggtttctt ccgccccctc ccatatgaaa taaacttcct ccccttcccg gtattccttc
     3781 aaatctgccg tcacatgaac ttctgctctc agactatcct tcgaggtgac tgtcacctga
     3841 aactgatcca caaagctgtc ggcccgttcc tgtcctctct gaatttctga ggaaatccca
     3901 cgaaccgtat cagttacact gccctccatc tggctgactt ttacctgcag ttcctgcacc
     3961 tggcgaagaa ggctcctgtt ctctccggcc agaaagaaaa gtccgcctgc cactaaaacc
     4021 aggttcgccg tcccaagaca aatcaaaatc gtttcttttc cgggctttaa ttttcgttct
     4081 ttcatctgat gccccctttc tttgggagat gtggcgcttc gtgttgtggg gttattgtac
     4141 tatgcccact aagctcgaaa agacctcgct aagtgggaca ggtatgtatt ctcactagac
     4201 tcgtgaaaaa cctcgtcaag tgttcatatt ataccatatc agcaggaaaa caagcggctg
     4261 cgaagcagac atttgttttc acctgatatg gtaacgacaa aatgttttag ctgccagaga
     4321 cggcggcaga tgtgcgcagc acagctgtat tttggagtta ttataccata tcaatgttca
     4381 gaatgtcttt acgatattct tacacatttt aatttctttt aaatcatttt aaaattataa
     4441 atttatgctt atcttcaaag tatcgaaata ccgcattaaa gttatcaagg caattttagg
     4501 acatcaatga taaagtttat tctaaactcc gtaagtaaaa tggtggggtt atagaattta
     4561 ttacctgtat aaataactag tagtttcaaa tgaaaaaaga catgacatta tatagataga
     4621 tatacctaaa cacattttca aaagtatttt ctatatcaat aatatttttc acattttc
//
LOCUS       DBMDUW010000096         4606 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_6964_length_4606_cov_3.363596, whole genome shotgun sequence.
ACCESSION   DBMDUW010000096 DBMDUW010000000
VERSION     DBMDUW010000096.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 4606)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 4606)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4606
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6964_length_4606_cov_3.363596"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..221
                     /locus_tag="ACZPCR_11750"
     CDS             <1..221
                     /locus_tag="ACZPCR_11750"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231565.1"
                     /translation="ISPNLKKIFEKGERGEVLTLLLADGRRVKCRFEMLTYANKSDTD
                     DTDVMVARIKYGDGIGELLAEEDIKEVF"
     gene            257..1474
                     /locus_tag="ACZPCR_11755"
     CDS             257..1474
                     /locus_tag="ACZPCR_11755"
                     /inference="COORDINATES: protein motif:HMM:NF021494.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2213 domain-containing protein"
                     /protein_id="HIR1231566.1"
                     /translation="MLSYYGYTISPNQIETGEGFLICRNVPIARTGTQEYMGREIGLT
                     GQNADKIITVRREPEEVFSSAALASFEGKPATNDHPPDLIGPDDVGLYEKGHAQNIRR
                     GVGDWADYIVADLHIHDRELIEAIQNGKREISCGYECDYVDNGDGTYSQKNIRGNHVA
                     VVERGRAGKRAAILDSIQTSAFTPERKERSMKHTFLQLFGLAAKDKTAEEIAKLAMDT
                     ADALDEEGSKPAEGTSGEEKQDPPSEGMDESLIDNIAEKVLARMEEKKAAEKQEEGKD
                     PFDEALEKLTEGETEPGGETGTEARVVPAEGADGGACSLDKALAAGILKTMRPAVAAI
                     QDEKQRMAVSDALLRCVTAQNQESDLSKILGAAQKNAQKAADSHPAMDLDQIQAAYDR
                     LNPHNPNYGKESR"
     gene            1475..1984
                     /locus_tag="ACZPCR_11760"
     CDS             1475..1984
                     /locus_tag="ACZPCR_11760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="structural cement protein Gp24"
                     /protein_id="HIR1231567.1"
                     /translation="MKGQVIGKTMTHGYAGSYSRQPDSVVNTRPAGGKEAIPFGLGVA
                     YDNDGCVVVMGTAGAKNSFVGVAVREVKSAWDYRNQNEGSYLPGDAVPVLMRGSVNVI
                     CQRSTPSLGGAVYIRTAVNESYPNCVIGGFEAENDEGKTTLLGNCQWGGQADENGVAE
                     LIILTRANA"
     gene            1995..3020
                     /locus_tag="ACZPCR_11765"
     CDS             1995..3020
                     /locus_tag="ACZPCR_11765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2184 domain-containing protein"
                     /protein_id="HIR1231568.1"
                     /translation="MAFKNVGTANLGMASSGQAKAFAMDAAGIASGQAFLTSELEKRD
                     MLVRTPLTSFTYSRDIPVRVGGGWTETVSAMQVGYGVTGGSGEGLITGASANGIPMVQ
                     ADFSKGLYKAHMIAAGTRVQWIDMQRGNMTGRNMDALLRDGLRMAYDKHMDENTYVGF
                     KTYGTTGLVNHPDAVITDAAASGAGSSTKFADKTPDQILADINTAILTAWAASEYDLD
                     AIPNHIIMPYEQYNYLATTKVTELAEKTILTFLLENNVAKQNGSDLFIGATSWCKGAA
                     ADGSSDRMVVYCNKERYLAMDELAPLTRAMTTPNTQQFCYDTAYAGNVSEVEVFYDQT
                     ILYVDKI"
     gene            3032..3370
                     /locus_tag="ACZPCR_11770"
     CDS             3032..3370
                     /locus_tag="ACZPCR_11770"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231569.1"
                     /translation="MFIVSKRNFLVRRADGSSYLVKKDFVGEIPQDVFDSTVIQGAIK
                     GGLAAVPSTRKDKDLYQAEQTAQEKEEECDLRPDTQAEKTPDEEGTSDGEHKSDKESE
                     PAEKQKRSRR"
     gene            3382..3915
                     /locus_tag="ACZPCR_11775"
     CDS             3382..3915
                     /locus_tag="ACZPCR_11775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4054 domain-containing protein"
                     /protein_id="HIR1231570.1"
                     /translation="MQPYGSFNPMAPYFQTARETAANIPQPGERGTYLKEMFQEDFPQ
                     FCQLYTQSGSDEEPVKLLLPETMLQTFIDQANDSVLPSRWGSLWRYAAGLYVAHFSAL
                     YLKTYAPGSRNAAQAAGKASQVGMVKEAAMGDTTLSYDNSAVTAGTEKWGTWNATQYG
                     QQLVTMARQVGMGGMLV"
     gene            3912..4310
                     /locus_tag="ACZPCR_11780"
     CDS             3912..4310
                     /locus_tag="ACZPCR_11780"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231571.1"
                     /translation="MIFDNPIFSDWYTDTVDVYRVVNVENGNITAQERKQVGKGIPCR
                     IYNSQKSSPSMRDTAAQVQASEKLACSLEEDIRAGDELLIVRGGALGMEGEPERYFAG
                     KPQKYYDPVGGAMTGLEHQEIGLFMQEIVR"
     gene            4390..>4606
                     /locus_tag="ACZPCR_11785"
     CDS             4390..>4606
                     /locus_tag="ACZPCR_11785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HIR1231572.1"
                     /translation="MMEVAEGATIEAVRVATEHTPPNGGAAIAGTNTRSGQMAQHWGT
                     DSITKPVYSGGSVRTVLANDMQYASYVN"
BASE COUNT         1315 a          943 c         1393 g          955 t
ORIGIN      
        1 agatatcgcc aaacttaaag aagatatttg aaaagggaga acgcggagag gtattaacgc
       61 tgctgttagc agatggcaga cgcgttaaat gcagatttga aatgctcaca tatgccaata
      121 aatccgatac agacgatacg gatgttatgg tcgcccgaat aaaatatgga gatggcattg
      181 gggaattact ggcagaagaa gatataaaag aagtttttta gtttcacttt gatgtcgcaa
      241 caaaaggagt tatattatgt tatcctacta tggttacacc ataagcccta accagataga
      301 aactggcgag ggctttttaa tttgcagaaa tgtccctatc gctcgaactg ggacgcagga
      361 atacatgggg cgggagattg ggctgacagg ccagaatgca gataagatta tcaccgtaag
      421 gcgggaaccg gaggaggtat tttcctctgc tgctcttgcg tcctttgagg ggaaaccggc
      481 gacaaacgac cacccgcctg acttgatagg accggacgat gtgggcctat atgaaaaagg
      541 ccatgcccaa aacatccgga gaggggtagg agattgggca gattatatag tggcggattt
      601 acatatccat gacagggagc tgattgaagc cattcagaat ggaaagaggg agatcagctg
      661 tggttatgag tgcgattatg tcgacaatgg agacggcact tacagccaga agaatatcag
      721 agggaatcat gtggcagtcg ttgaacgggg cagagccggg aaacgggctg ccattttaga
      781 ttcaatacaa acatcggcgt tcacgccaga aaggaaagag agaagtatga aacacacgtt
      841 tttacagttg tttgggcttg cggccaagga taagactgct gaggagattg caaagctggc
      901 tatggacaca gccgacgccc tggacgagga aggctctaag ccagcggaag gaacgtctgg
      961 ggaagaaaaa caggatcctc cgtcagaagg tatggatgag tcactcattg acaacatcgc
     1021 agaaaaggtt cttgccagaa tggaagaaaa aaaggctgct gaaaagcagg aggagggaaa
     1081 ggatcccttt gacgaggcgc ttgaaaagct gacagaagga gaaacagaac caggaggaga
     1141 aaccggtaca gaagcccgcg tagtgcctgc agagggggca gacggaggcg cttgcagtct
     1201 ggataaggct ctggcagcag ggattctgaa aacgatgcgt ccggcagtgg cggcgattca
     1261 ggacgaaaag cagagaatgg ctgtatcaga cgcactgctt cgctgcgtga cagcgcagaa
     1321 tcaggagagt gatctttcta agattctcgg tgcggctcag aaaaacgcgc agaaggcggc
     1381 ggacagccat cctgcaatgg atctggacca gattcaggct gcctatgacc gtttgaatcc
     1441 acacaaccct aattacggaa aggagagcag atagatgaag ggacaggtaa ttggaaagac
     1501 aatgacgcat ggatatgccg gcagttattc tcgccagcca gattcggtag tcaatacacg
     1561 gccagcagga ggaaaggaag ccattccgtt cggcttggga gtggcctatg acaatgacgg
     1621 ttgcgtggta gtgatgggaa ctgcaggcgc gaagaacagc tttgtgggcg tggcagtccg
     1681 tgaagtgaaa agcgcgtggg attaccggaa ccagaacgag ggttcttatc tgcccggcga
     1741 cgcagtccct gtgctgatgc gcggatcggt caacgtcatc tgccagagga gcacgccgtc
     1801 tctgggcgga gccgtgtata tccggactgc agtcaatgaa tcctatccaa actgtgtgat
     1861 tggaggattt gaggctgaaa acgacgaagg aaagactact ctgctcggga actgccagtg
     1921 gggcggccag gcagatgaaa acggcgtagc ggaattgatc attttaacga gagccaatgc
     1981 gtaggaggta agatatggca tttaaaaacg taggaacagc gaatttaggc atggcctcca
     2041 gcggccaggc aaaagcattt gcaatggatg cggcaggaat tgcgtctggc caggcctttc
     2101 tgacatctga gctggaaaag agagatatgt tagtacgtac tccgcttacc agttttacat
     2161 acagcagaga tattccggtc cgcgtcgggg gaggatggac tgagaccgtg tctgccatgc
     2221 aggtaggcta tggggtaacc ggaggttcgg gagagggtct tatcacagga gcttctgcaa
     2281 acggtattcc gatggtacag gcagattttt ccaagggact ttacaaggct catatgattg
     2341 ccgccggaac ccgtgtgcag tggattgata tgcagcgcgg aaacatgacc ggaaggaata
     2401 tggacgctct gctccgggat ggacttcgaa tggcctatga taagcatatg gacgagaata
     2461 cctatgtagg ctttaagact tatggaacaa ccggccttgt aaatcatccg gatgcggtga
     2521 ttacagacgc agccgcatct ggagcaggaa gcagtacaaa gtttgctgat aagacaccag
     2581 atcagatttt ggcggatatc aatacagcaa ttttgaccgc ttgggcggca tcagagtatg
     2641 acctggatgc aattccaaac cacattatca tgccgtatga gcagtacaat tatctggcta
     2701 ctacgaaggt aacggagctg gcagaaaaga cgattcttac cttccttctg gagaacaacg
     2761 tggccaagca gaatggatca gatctgttta tcggtgcaac atcctggtgc aaaggggccg
     2821 ctgcagacgg ttcttctgac cgaatggtgg tctactgcaa caaggagcgc tatctcgcaa
     2881 tggatgagct ggcgccgctt accagggcca tgacaacgcc caacactcag cagttctgct
     2941 atgatacggc ctatgcagga aacgtatctg aggtagaagt attttatgat cagacgattc
     3001 tgtatgtgga taaaatttaa aggagggtgc tatgtttatt gtatcaaaac gaaattttct
     3061 ggtgagacgg gcagatggct cgtcttattt agtgaagaag gattttgtgg gagagattcc
     3121 tcaggatgta tttgacagta cagttattca gggagcaatt aaaggtggcc ttgcggcagt
     3181 accttctaca agaaaagata aggacctgta tcaggcggag cagacggctc aggagaaaga
     3241 agaggaatgt gatcttcgtc cagatactca ggccgaaaag acgccagatg aggaagggac
     3301 atcagacgga gaacataaat cggacaagga gtctgaaccg gcagaaaagc agaaacgctc
     3361 cagaagatag gaggtgattc tatgcagcca tacggtagtt ttaatccgat ggctccatat
     3421 tttcagacag ccagagaaac agcggctaac ataccgcagc caggggagcg agggacgtat
     3481 ttgaaagaga tgttccaaga ggattttccg cagttttgcc agctctacac tcagagtgga
     3541 agtgatgagg aacctgtaaa acttttgctc ccggagacta tgcttcagac attcatagac
     3601 caggcaaacg acagcgtgct tccctccagg tggggaagcc tctggcgtta tgcagcagga
     3661 ctttatgtgg ctcatttttc tgcgctgtat ctgaaaacct acgcccctgg ctccagaaac
     3721 gccgcccagg cggctggaaa ggcgtcccag gtgggaatgg tcaaagaagc tgcaatgggg
     3781 gatactacgc tcagctacga caacagcgcc gtgacagccg gaacagagaa atggggaacc
     3841 tggaatgcaa cccagtatgg ccagcagctg gtgacaatgg cgaggcaggt aggaatggga
     3901 gggatgctgg tgtgatattt gataatccga ttttttcaga ttggtacacg gatacagtgg
     3961 atgtgtaccg ggtggtgaat gtggaaaatg gcaatattac cgctcaggaa agaaaacaag
     4021 taggaaaagg cattccctgt cgtatataca atagtcagaa aagcagtcct tccatgagag
     4081 acactgctgc tcaggttcag gcgtctgaga agctggcctg cagcctggag gaagatataa
     4141 gggcagggga tgaactgctg attgtacggg gcggtgcgct cggcatggag ggggagccgg
     4201 agcggtactt tgcaggaaag ccgcagaaat actatgatcc ggtgggcgga gccatgacag
     4261 gactggaaca tcaggagatc ggcctgttta tgcaggagat tgtgaggtga caggatgtca
     4321 agctttggca gccagataag aaagcgcttg gcggaactgc gcagggctgg ggaagatgtg
     4381 ccgaaaatta tgatggaggt ggcagagggg gccactatcg aggcagtgag ggtggcaact
     4441 gagcatacgc cgccaaacgg cggggcggcg attgccggta cgaataccag aagcggacag
     4501 atggcccagc actggggaac ggatagtatt acgaaaccag tgtattctgg tggcagcgtc
     4561 cgaacggttc tggcaaacga tatgcagtat gcgtcctacg tcaatg
//
LOCUS       DBMDUW010000097         4301 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_7499_length_4301_cov_3.386429, whole genome shotgun sequence.
ACCESSION   DBMDUW010000097 DBMDUW010000000
VERSION     DBMDUW010000097.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 4301)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 4301)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4301
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7499_length_4301_cov_3.386429"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..121
                     /locus_tag="ACZPCR_11790"
     CDS             <1..121
                     /locus_tag="ACZPCR_11790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HIR1231573.1"
                     /translation="HSPSVENIEVVRRGKVRRAKLNYLRDRVGKAAKVKELVK"
     gene            226..1140
                     /gene="ylqF"
                     /locus_tag="ACZPCR_11795"
     CDS             226..1140
                     /gene="ylqF"
                     /locus_tag="ACZPCR_11795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004841723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HIR1231574.1"
                     /translation="MNIQWYPGHMTKAKRAMKEDIKLIDLVIELVDARMPLGSRNPDI
                     DDLARGKGRMILLNKADLADERKNEQWTSWFKAQGFHVVKINARTGMGLKQITPLVQE
                     ACREKIERDRRRGIKNRPVRAMVVGIPNVGKSTFINSFAGKACAKTGNKPGVTKGNQW
                     IRLNKTLELLDTPGILWPKFEDQAIGMNLAFIGSINDEILDKTELAAELARFLIIHYR
                     GMMEERYQLEEGTDYEPYQVLEQIARIRACLLKGNELDIKKAANLFLDDFRSGKLGRI
                     SLEFPPSVPSEDSGRTAEADEEAQHENA"
     gene            1127..1789
                     /locus_tag="ACZPCR_11800"
     CDS             1127..1789
                     /locus_tag="ACZPCR_11800"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HIR1231575.1"
                     /translation="MRTLKGEKLEQELLRLEAMKEYEKKYGAGAVVCGIDEAGRGPLA
                     GPVVAGACILPADCQILYLNDSKKLSEKRREALFEEIKEKAVAFGVGIVSPAVIDEIN
                     ILQATYEAMRQAVNKLPVAPDIFLNDAVIIPGIEENRQVKIIKGDAKSVSIAAASILA
                     KVTRDHMMAEYDSLYPQYGFAKHKGYGTKAHLDAIREYGMCPIHRRSFLKKFEEREAV
                     ND"
     gene            1782..2138
                     /locus_tag="ACZPCR_11805"
     CDS             1782..2138
                     /locus_tag="ACZPCR_11805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HIR1231576.1"
                     /translation="MTDRASRRAVGTHYEEEAARYLEQQGYQILERNFFSRYGEIDLI
                     AKDEDTLVFVEVKYRSGASFGDPSEAVTAKKQERIRKTARYYLCARQLSEDTPCRFDV
                     AAVLGSQIRLIKHAFY"
     gene            2172..3029
                     /gene="pgeF"
                     /locus_tag="ACZPCR_11810"
     CDS             2172..3029
                     /gene="pgeF"
                     /locus_tag="ACZPCR_11810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002603972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HIR1231577.1"
                     /translation="MSEIKFKKRDERDVLAVKESAGVTYLSFPALENTGLVSHAFSTR
                     LGGVSKGDYATMNFSFTRGDNRDDVLENYARMARALGVEREKMVLTYQTHTVNVRQVT
                     EEDAGKGVVRERDYTDVDGLITDIPGITLVTFFADCVPLYFLDPVHRAIGLSHSGWRG
                     TVKGMGRVTAEAMRDAFGSRPEDLIACIGPSICADCYEVGPEVAEEFAQAFSQTCHSA
                     ILEKKPDGKYQLDLWRANQIVLEEAGLKPENTSVTNICTHCNPDLLFSHRRSAERRGN
                     LCAFLCLKP"
     gene            complement(3179..3382)
                     /locus_tag="ACZPCR_11815"
     CDS             complement(3179..3382)
                     /locus_tag="ACZPCR_11815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003690 - double-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HIR1231578.1"
                     /translation="MSTNNNTTNVPEAKEAMNRFKMEVAGELGVPLSNGYNGNLTSAQ
                     NGSVGGYMVKKMIEAQERQMAGK"
     gene            3682..4248
                     /gene="rsmD"
                     /locus_tag="ACZPCR_11820"
     CDS             3682..4248
                     /gene="rsmD"
                     /locus_tag="ACZPCR_11820"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016438552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HIR1231579.1"
                     /translation="MRVIAGSARRLLLKTPEGMETRPTTDRIKETLFNMIQDDLYHCQ
                     FLDLFSGSGAIGIEALSRGARQAVFVENHPDAVETIRSNLKTTRLEEQAIVMNCDVMT
                     ALKRLEERGFSFDFIFMDPPYNCFHEKRVLEYLAHSSLVTQDTVILVEASRETDASYL
                     SDLGFQLDRVKEYKTNKHLFISLSDCNS"
BASE COUNT         1123 a         1020 c         1141 g         1017 t
ORIGIN      
        1 acattctcct tccgttgaga acatcgaggt agtaagacgc ggtaaagtaa gaagagctaa
       61 gttaaactac ttaagagaca gagtcggcaa ggctgctaag gtaaaagagt tagttaaata
      121 attcttgcaa ttaaagggac aatgaaaatt gtccctttct ttactttata cggaaattta
      181 tatttaaaaa gaacaatttg aatcaaacgc agagaggaac gcactatgaa tatacaatgg
      241 tacccaggcc acatgacaaa ggccaagcgg gcaatgaagg aggatatcaa gctcatcgat
      301 ctggtgatcg agctggtgga cgcgagaatg cctctgggaa gccgaaaccc tgatattgac
      361 gatctggcca ggggaaaggg ccgcatgatt cttttaaaca aggcagatct ggcagacgag
      421 cggaagaacg agcagtggac gtcctggttt aaggcccagg gctttcatgt ggtgaagatt
      481 aacgcccgca cgggcatggg gttaaagcag attactcctc ttgttcagga ggcctgccgg
      541 gaaaagattg agcgggatcg gcgcagaggc atcaagaacc gtccggtccg cgctatggtc
      601 gtaggcatcc caaacgtagg aaaatccacc tttattaatt cctttgcagg aaaagcctgc
      661 gccaagacgg gcaacaagcc tggcgttacc aagggaaatc agtggatccg cctgaataag
      721 actctggagc ttttagatac tcctggaatc ctgtggccga aatttgagga tcaggccatc
      781 ggcatgaatc tggcttttat cggctccatc aacgatgaaa ttctcgataa gacagagctg
      841 gccgcagagc tagcgcgttt cctgataatc cattaccgcg gcatgatgga ggagcggtat
      901 cagctggaag aagggacaga ctatgagccc taccaggtgc tggagcagat tgccagaatc
      961 cgcgcctgcc tcttgaaggg aaacgagctg gacattaaaa aggctgccaa tctgttcctg
     1021 gatgatttca gaagcggcaa gcttggacgg atctccctgg agtttccgcc gtctgtcccc
     1081 tctgaagaca gtgggcgcac agcagaagca gacgaggagg cacagcatga gaacgcttaa
     1141 gggtgaaaag ctggaacagg agcttctccg cctggaagcc atgaaggaat atgaaaaaaa
     1201 atacggggca ggagccgttg tctgcggcat cgacgaggca ggcagaggcc ctctggccgg
     1261 tccggtggta gccggagcct gcattctgcc tgcggactgc cagattctct atctgaacga
     1321 ttccaaaaag ctgtcggaaa aacggcggga ggctctgttt gaagagatta aagaaaaggc
     1381 ggtcgccttt ggcgtaggaa tcgtgagtcc ggctgtcatt gatgagatta atattcttca
     1441 agccacctat gaggccatgc gccaggctgt aaacaagctg cctgtcgctc cagatatctt
     1501 tttaaacgac gcggtcatta tccctggaat tgaggagaac cggcaggtga agatcatcaa
     1561 gggcgatgcg aaaagcgttt ccatcgcggc ggccagcatt ctggccaagg tgacaaggga
     1621 tcacatgatg gcagagtacg acagcctcta tccccagtac ggctttgcaa agcacaaagg
     1681 ctatgggaca aaggctcatt tagacgccat ccgcgagtac ggcatgtgcc cgattcatag
     1741 aagaagcttt ctgaagaaat ttgaggagag ggaggctgtc aatgactgac agagccagca
     1801 ggagagcggt gggcacgcac tatgaagagg aagcggcccg atatctggaa cagcagggat
     1861 accagatttt agagcggaat ttcttcagcc gttatgggga aattgattta atcgcaaagg
     1921 atgaggatac ccttgtcttt gtggaggtca aataccgctc cggcgcgtct tttggcgatc
     1981 cgtcggaggc tgtgacggca aaaaagcagg agcggatccg aaaaacggcc cgctattatc
     2041 tctgcgcacg ccagctttcc gaggatactc cctgccgctt tgacgtggca gctgtgctgg
     2101 gatcccagat ccggctgatc aaacatgctt tttattagac tttttatcag atgaagttca
     2161 aggagaaaca gatgagcgaa atcaaattta aaaaacgaga tgagcgggat gtgctggctg
     2221 taaaggaaag cgccggcgtc acttacctga gcttcccggc tctggagaac accggcctgg
     2281 tatcccacgc cttttccacc cgtctgggag gcgtcagcaa gggagactac gccaccatga
     2341 atttttcctt tacaagaggc gacaaccggg acgacgtact ggaaaattat gcacgaatgg
     2401 cccgggctct cggcgtggag cgggagaaga tggttctcac ctatcagaca cacacggtca
     2461 atgtaagaca ggtaacagag gaggacgctg gaaaaggcgt ggtcagagag cgggattaca
     2521 cagatgtgga cggactgatt acagatattc caggcattac cctggtcacc ttttttgccg
     2581 actgcgtgcc tctctatttc ctggatcctg tccaccgggc catcgggctg tcccactccg
     2641 gatggcgcgg cacggtcaag ggaatgggcc gggtaactgc agaagccatg agagacgcct
     2701 tcggatcccg cccggaggat ctgattgcct gcatcggccc cagcatctgc gccgactgct
     2761 atgaagtggg tcctgaggtg gcagaggagt ttgcacaggc cttctctcaa acctgtcatt
     2821 ccgctatttt agaaaaaaag ccggacggaa agtaccagct ggatctgtgg agagccaacc
     2881 agattgtgct ggaggaggca gggcttaagc cagagaatac ctctgtcacc aatatctgca
     2941 ctcactgtaa tccggatctt ttattttccc accgaaggag cgcggagcgc agaggaaatc
     3001 tgtgcgcctt cctctgcctg aagccataag ccagatacga caaagagcat gcactgcgaa
     3061 agatatttcg tcttctgcag tccatgctct ctgcattttt gcattcaccc tgctaataca
     3121 gagtctgcgc tttctgaagt cctatctcct caggagacag cctctttttc agacaggcct
     3181 atttgccggc catctgtctc tcctgcgcct cgatcatctt ctttaccata tagcctccga
     3241 ctgatccatt ctgtgcagaa gttaagtttc cgttgtagcc gttgcttaac ggaacgccga
     3301 gttcacctgc gacctccatc ttaaagcggt tcattgcttc ctttgcctct ggtacatttg
     3361 ttgtgttgtt atttgtagac ataacaaacc ctccttttca tctgacgccc atgcagttat
     3421 tttcttttgt gtgtttcatg ggcttttgtt tttgctacat tcctagtatg tgtcaaatgg
     3481 tctgtaatac actggcatct tttgagcctt tttccaatgt ctgcctgcgg tttgaacgct
     3541 gcttttgaaa cgggcttttt ctcgaatctt ttaattttgc cttgtatatc aggccattac
     3601 atactataat atgctgtgac gagcgcgtgg attgaaattc tctcctgcgc gccgccaata
     3661 atcagacagc aggaaaaata gatgagagta atagccggca gcgccagaag gctgctttta
     3721 aagacaccgg aagggatgga aaccagaccg accacagacc ggattaagga aaccttattt
     3781 aatatgattc aggatgattt gtatcactgc cagttcctag acctgttttc agggagcggc
     3841 gccatcggaa tcgaggcctt aagccgcgga gccaggcagg ccgtatttgt ggagaaccat
     3901 cctgatgctg tagagaccat ccgcagcaac ctgaagacta cgcgtctgga ggaacaggcc
     3961 attgtcatga actgcgatgt aatgacagct ttaaaacgtc tggaggagcg aggattttcc
     4021 tttgatttta tttttatgga tcccccctat aactgttttc atgaaaaacg ggtcctggaa
     4081 tacctggccc attcttccct ggtaacgcag gacactgtga tcctcgtgga ggcttccagg
     4141 gagacagatg cctcctatct ttccgatctt ggttttcaac tggatcgggt aaaggagtat
     4201 aaaacaaaca agcatttatt tatcagtcta tctgactgca attcttaaac accaaaggag
     4261 aaaacagtac tatgaaaaca gccatttatc cgggaagctt c
//
LOCUS       DBMDUW010000098         4192 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_7719_length_4192_cov_3.219751, whole genome shotgun sequence.
ACCESSION   DBMDUW010000098 DBMDUW010000000
VERSION     DBMDUW010000098.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 4192)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 4192)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4192
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7719_length_4192_cov_3.219751"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     misc_binding    33..272
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            372..1391
                     /gene="pheS"
                     /locus_tag="ACZPCR_11825"
     CDS             372..1391
                     /gene="pheS"
                     /locus_tag="ACZPCR_11825"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007858698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HIR1231580.1"
                     /translation="MREQLEKIKAEALAKIEASDALEKLNDIRVAYLGKKGELTSVLK
                     SMKDVAPEERPKVGQMVNDARALIEAKLEETKNKLARLAREEQMKREVIDVTLPAKKN
                     HVGHSHPNTIALEEVERIFIGMGYEVVEGPEVEYDKYNFEKLNIPKGHPARDEQDTFY
                     INDSVVLRSQTSPVQVRTMETRKPPIRIIAPGRVFRSDEVDATHSPSFHQIEGLVIDK
                     NITFADLKGTLAEFARELFGEETKVKFRPHHFPFTEPSAEVDVSCFKCGGKGCRFCKG
                     SGWIEILGCGMVHPHVLEMCNIDPEEYSGFAFGVGLERIALLKYEIDDMRLLYENDVR
                     FLKQF"
     gene            1466..3913
                     /gene="pheT"
                     /locus_tag="ACZPCR_11830"
     CDS             1466..3913
                     /gene="pheT"
                     /locus_tag="ACZPCR_11830"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002575007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HIR1231581.1"
                     /translation="MNTALSWIKAYVPDLDVTAQEYTDAMTLTGTKVEGYECLDKNLE
                     KIVVGQILKIDRHPDADKLVICQVDLGGEVTQIVTGAPNVEVGQKVPVVLDGGKVAGD
                     HDGGRPEDGVKIKKGKLRGVESNGMMCSVEELGSSREMYPDAPELGIYVFPDDVEVGS
                     DAVEALGLRDVVFEYEITSNRVDCYSVIGIAREAAATFRKQFCEPEIKATGNSEDIHD
                     YLKVSVEDTKLCPRYCARMVKNIKLAPSPDWMRRRLAASGIRPINNIVDITNYVMEEY
                     GQPMHAYDYDQIAGKEIVVKCAKDGEVFQTLDGQERQLDSQILMINDGEKAVGIAGIM
                     GGENSKITDDVKTMVFEAACFDGTNIRLSAKRVGLRTDASGKFEKGLDPNTAELAINR
                     ACQLIEELGAGEVVGGMLDVYPVKKEGNRVAFEPEKINRLLGTDISKEDMISYLKSVE
                     LEYDEKTNEIVVPSWRQDVHRMADVSEEVARFYGYDVIPTALPTGEATAGKLSFKLRV
                     EEIARRIAEFCGFSQSMTYSFESPKVFDKLLLPEDSALRRVVSISNPLGEDFSVMRTT
                     PLNGMLNSLSTNYNRRNKDVRLYELATVYLPVSEEENAKYLEETGLPALPDERQQFTL
                     GMYGNGDFFTMKGVVEEFLEKVGMKKKPHYNPEAGKSFLHPGRQALISYNGTVIGYMG
                     EVHPDVADNYKLGEKTYVAVLDMPEITANATFDHKYEGIAKYPSVTRDLSMVMKKEIL
                     AGQIEDVIEQRGGKILESYKLFDVYEGSQITAGYKSVAYSITFRSKDHTLEEKEVTSA
                     MNKILNGLQGLGIELRS"
BASE COUNT         1205 a          916 c         1209 g          862 t
ORIGIN      
        1 aaaaacagtg cgtaaaatat taaacagtat aagaaaaggc agtgaaggtg taagtagaag
       61 cttattttcc gtccagagag aggagatcat cggctgagag tcttctccgg ttcagataag
      121 agttcgaaat tcccaccaga gccgcgcagc tgaacagcag gccgcaaagg ggagctaagt
      181 aagcggcgac gtttcgtaca cgttacgtat aagataagag cctgcagcag caggaatcag
      241 ggtggtaccg cggtttatat cccgtccctt cgcgtgcgaa ggggcgggat ttttgttttt
      301 tgtataagaa atatcaggaa ggctctttgg cacacgacgc gcagatacaa tcgatagaag
      361 aaggagatat tatgagagag cagttagaga aaatcaaggc tgaggccctt gcgaagatcg
      421 aagcctccga cgcgctggaa aagttaaacg atatccgcgt cgcatacctt ggaaaaaagg
      481 gcgagctgac cagcgtttta aagagcatga aggacgtagc tcctgaggag cgcccgaagg
      541 taggccagat ggtaaatgat gccagagctt taatcgaggc caagttagag gagaccaaga
      601 acaaactggc tcgtctggcc cgcgaggagc agatgaagag agaggtgatt gacgtaactc
      661 ttcctgctaa gaagaaccat gtaggccaca gccatccaaa taccatcgct ttagaggaag
      721 tagagagaat cttcatcgga atgggctacg aggtagtgga aggtcctgag gtggagtatg
      781 ataagtacaa ctttgagaaa ttaaacattc cgaagggaca tccggccaga gacgagcagg
      841 atactttcta catcaatgat tctgttgtcc tcagaagcca gacttccccg gttcaggtcc
      901 gcaccatgga gacaagaaag cctccgatcc gcattattgc gccgggccgt gtattccgtt
      961 ccgacgaggt agacgcaacc cactctccgt ccttccatca gattgaggga cttgtcattg
     1021 acaagaacat tacgtttgca gatctgaagg gaaccctggc cgagttcgcc agagagctgt
     1081 tcggagagga gacaaaggta aaattccgtc ctcaccattt cccgttcaca gagccgtctg
     1141 ctgaggtgga cgtaagctgc ttcaagtgcg gaggcaaggg ctgccgtttc tgtaagggat
     1201 ccggctggat tgagatttta ggctgcggca tggtacatcc ccacgtgctg gagatgtgca
     1261 acatcgatcc ggaggaatac tcaggattcg ctttcggtgt gggacttgag agaattgctc
     1321 tcttaaagta cgagattgac gatatgagac tgctgtatga aaacgacgtg cgctttttaa
     1381 agcagttcta agcgttttca aatcagacag gagtaaccga taaagggttc cgtagagaac
     1441 cgattagatt gcaaggagaa ataagatgaa cacagcatta tcatggataa aagcatatgt
     1501 tccggatctg gacgttacag cccaggagta caccgacgct atgacgctga caggaacaaa
     1561 ggtagagggc tacgagtgtc tggacaagaa tctggagaag atcgtggtag gacagatttt
     1621 aaagattgac cgccatccgg acgcagacaa gctggtgatc tgtcaggtag atctgggcgg
     1681 cgaagtaacc cagatcgtca caggagcgcc taacgtagag gtgggacaga aggttcccgt
     1741 ggttctggac ggcggaaagg tagccggaga tcatgacggc ggccgccctg aggacggagt
     1801 aaagattaaa aagggcaagc tgcgcggcgt agagtctaac ggcatgatgt gctccgtgga
     1861 ggagctggga tccagccgcg agatgtatcc ggacgctccg gagcttggaa tttacgtatt
     1921 cccggacgac gtagaggtgg gaagcgacgc agtggaagct ctgggcctca gagacgtagt
     1981 atttgaatac gagattacct ccaaccgcgt ggactgctac agcgtgatcg gaattgccag
     2041 agaggcagcc gctaccttca gaaagcagtt ttgcgagccg gagattaagg ctacaggaaa
     2101 cagcgaggat attcacgact acctgaaggt aagcgtggag gatacgaagc tgtgcccgcg
     2161 ctactgcgcc agaatggtaa agaacattaa gctggctccg tctccggact ggatgcgccg
     2221 ccgcctggct gccagcggta tccgtccgat taacaacatc gtagatatca caaactatgt
     2281 gatggaagag tacggacagc caatgcacgc ttacgattac gaccagattg ccggaaagga
     2341 gatcgtggta aaatgcgcta aggacggcga agtgttccag actctggacg gccaagagag
     2401 acagctggac agccagatcc tcatgatcaa cgacggagag aaggcagtgg gaatcgccgg
     2461 aatcatggga ggcgagaatt ccaagattac agacgacgtg aagaccatgg tattcgaggc
     2521 agcctgcttc gatggaacca atatccgcct ctctgccaag agagtgggac tgagaacaga
     2581 cgcttccgga aagtttgaga agggactgga tcccaacaca gccgagcttg ccatcaaccg
     2641 cgcctgccag ctgattgagg agctgggagc cggagaggtt gtaggaggca tgttagacgt
     2701 ttacccggta aagaaggaag gaaaccgcgt ggctttcgag ccggagaaga ttaaccgcct
     2761 tctgggaacc gatatttcca aggaagacat gatttcctac ttaaagagcg tagagctgga
     2821 atacgatgag aagacaaatg agatcgtggt tcccagctgg cgtcaggacg ttcacagaat
     2881 ggcagatgtg tctgaggagg ttgcccgttt ctacggttac gacgtgattc cgaccgccct
     2941 gcctacaggc gaggctactg ccggaaagct gtccttcaag ctgagagtag aggaaattgc
     3001 cagaagaatc gcagagttct gcggattctc tcagagcatg acctactcct tcgagagccc
     3061 gaaggtattt gataagcttc tgcttccgga ggattctgca cttcgcagag tggtttccat
     3121 ttccaacccg ctgggagagg atttcagcgt tatgagaacc actccgttaa acggaatgtt
     3181 aaactctctc tccacaaact acaaccggag aaataaggat gtaagactct acgagctggc
     3241 taccgtttac ctgcctgtaa gcgaggagga gaacgccaag tacctggagg agacaggact
     3301 tccggcgctt ccggacgagc gtcagcagtt cactctggga atgtacggaa acggcgattt
     3361 cttcaccatg aagggcgtag tagaggagtt cctggagaaa gtgggaatga agaaaaagcc
     3421 tcattacaat cctgaggcag gaaagagctt cctccatccg ggacgccagg ctctcatttc
     3481 ctacaacggc acagtgattg gatatatggg cgaggttcat cctgatgtgg cggacaacta
     3541 caagctgggc gagaagacct atgtggcagt tctcgatatg cctgagatca ctgcaaacgc
     3601 tacctttgac cacaagtacg aaggaattgc caagtatccg tccgtgacaa gagacctgag
     3661 catggtaatg aagaaagaga ttctggcagg acagattgag gacgtgattg aacagagagg
     3721 cggcaagatt ctggaaagct acaagctctt cgacgtatac gagggaagcc agatcacagc
     3781 aggctacaag tcagtggctt actccattac cttccgctcc aaagatcaca ccttggagga
     3841 gaaggaagta acctccgcta tgaacaagat tctgaacgga cttcagggac tgggaatcga
     3901 gctgagaagc taaaaattcc tgatgaaggg ataaaaataa acagaatgaa tgtaagataa
     3961 cctggcgtct ctgccagtct gagggaaagt accatcaggc tggcggaggc gctttttgtg
     4021 taacaggaag acgcccagga caaacgcatg agtaaataaa ttgtgaacaa atcccctttt
     4081 tctggtatga taaaaagaaa aagggggttt tgctatggat gaattgttag aatggatgga
     4141 ttatattgaa gataagcgtc agcagacgaa agtacggcat aagctgaagg ac
//
LOCUS       DBMDUW010000099         2899 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_11837_length_2899_cov_2.197999, whole genome shotgun sequence.
ACCESSION   DBMDUW010000099 DBMDUW010000000
VERSION     DBMDUW010000099.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 2899)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2899)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2899
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_11837_length_2899_cov_2.197999"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..469
                     /locus_tag="ACZPCR_11835"
     CDS             <1..469
                     /locus_tag="ACZPCR_11835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HIR1231582.1"
                     /translation="ATMFTKEEYLKKAHIVNTKMKEMLNHKSLRYNWHEADVTVLEGV
                     MARGDRKVAAVIEEAYKNGALYDSWSESFKNDVWMKAFETCGVDPEFYTLRERSLDEV
                     FPWDFIDAGVSKEFLQREWNQALHETVTPNCRQKCSACGALKYKGGVCYENKN"
     gene            453..1223
                     /locus_tag="ACZPCR_11840"
     CDS             453..1223
                     /locus_tag="ACZPCR_11840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03936 family radical SAM-associated protein"
                     /protein_id="HIR1231583.1"
                     /translation="MKIRIKFRKQGAVKFVGHLDIMRYFQKVMRRADVDIRYSEGFSP
                     HQIMSFAAPLGVGLTSNGEYVDIEVNSTESSQEMVSRINAANVEGITVTSYRKLPDSA
                     KNAMSLVAAADYTMWFKDGYEPEDEDGFWTGLSHFLEKPSISIVKKTKKGVKEIDLKP
                     YLYEIVIESPFKGSTWKEDSSDSPERQGAGRIFMKLSAGSSVNIRPEQVIGAYYEAMG
                     QEYPPFAFQIQREEVYGEQGSEDCRRFVSLEEYGETIK"
     gene            1204..2448
                     /locus_tag="ACZPCR_11845"
     CDS             1204..2448
                     /locus_tag="ACZPCR_11845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E/G"
                     /protein_id="HIR1231584.1"
                     /translation="MEKPLNKLLITRWRNQILTALTENGKCRSLNLEPAEKTGILGNI
                     YIGKVKNIVKNINSAFIDLGNGLTGYYSLTDNKTHLFTDAAAKTQDSHRPLRQGDEIL
                     VQVERDAVKTKDPVLTSNLNFTGKYLVLTQGKKQIGFSGKIRDKAWKQHMQNLLEKET
                     AGSFGLSFGLIVRTNAREAGEEEILQELELLARRRQTLLASASHRTCYSLLASSEPSY
                     ISSIRDAYTSELEAVVTDDKDCYEAVRQYLEENQPEDLEKLSFYEDPMLSLSKLYSLE
                     TALEQALGKHVWLKSGGYLVIEPTEALTVIDVNTGKYAGKKTQAETIFKINQEAAAET
                     ARQLRLRNLSGIIVVDFIDMETEEERLRLMSLLERELLKDPVKTVLVDMTRLGLVEIT
                     RKKVKRPLAEQVRAAGYPIKEC"
     gene            2599..>2899
                     /gene="rplU"
                     /locus_tag="ACZPCR_11850"
     CDS             2599..>2899
                     /gene="rplU"
                     /locus_tag="ACZPCR_11850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012742535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HIR1231585.1"
                     /translation="MYAIIATGGKQYKVAEGDIIKVERLGAGAGETVTFDQVLAVNNG
                     ELKIGCPTVDGATVSATVVKEGKGKKVIVYKYKSKTGYHKKNGHRQLFTQVKIEKI"
BASE COUNT          858 a          619 c          757 g          665 t
ORIGIN      
        1 ggcaaccatg ttcaccaaag aggagtacct gaaaaaggct catatcgtaa acacaaagat
       61 gaaagaaatg ctgaaccata agagcctccg ctataactgg catgaggctg atgttactgt
      121 gttggagggc gttatggccc gtggtgacag aaaagtagca gctgtcattg aggaagctta
      181 taaaaacggc gctctctatg actcctggtc tgaaagcttt aaaaacgacg tgtggatgaa
      241 agcctttgaa acctgcggcg tagatcctga attctacacc ctcagagagc gttctctgga
      301 cgaagtcttc ccatgggatt tcattgatgc cggtgtttcc aaggaattct tacaaagaga
      361 gtggaatcag gctctccatg aaactgtcac acctaactgc cgtcagaaat gttctgcctg
      421 cggcgcatta aaatataaag gaggcgtctg ctatgaaaat aagaattaaa ttccgaaagc
      481 agggcgctgt caaatttgtc ggccacctgg atattatgcg gtatttccag aaggtaatgc
      541 gccgggctga tgtagatatc cgctacagcg agggcttcag cccgcatcag attatgtcct
      601 ttgctgctcc gctgggagta ggacttacca gcaacggtga atatgtagat attgaggtaa
      661 acagcacaga atcctcccaa gaaatggtaa gccggatcaa cgcagctaat gtagagggga
      721 tcacagtcac ctcctaccga aagcttcctg actccgcaaa aaatgccatg tctctggtag
      781 ctgcagctga ctacacgatg tggtttaaag acggctatga accggaagat gaggacggtt
      841 tctggacagg gttgtcccat ttcctcgaaa agccttccat ttctatcgtc aaaaagacaa
      901 aaaagggcgt taaggaaata gatttaaaac cctatctcta tgaaattgtg attgagagtc
      961 cttttaaggg aagcacctgg aaggaagatt cttccgacag ccctgagcgt cagggagcag
     1021 gcagaatctt tatgaaactc tctgccggaa gctctgtcaa tatccggccg gagcaggtaa
     1081 tcggcgctta ctatgaagcg atgggccagg agtatccgcc ttttgccttc cagattcaga
     1141 gggaagaggt ttacggtgag cagggcagtg aagactgccg tcggttcgtg tcattggagg
     1201 aatatggaga aaccattaaa taagcttctg attaccagat ggagaaacca gattctgaca
     1261 gctctgacag agaacggaaa gtgccgttcc ctgaatctgg agccggccga aaaaacagga
     1321 attctgggta atatctatat cggcaaggta aaaaatattg taaaaaatat taattctgct
     1381 ttcattgatc tgggaaacgg cctgactggc tattacagtc tcacagacaa taaaacccat
     1441 ctgtttacag acgctgcagc caaaacgcag gacagtcatc gtccccttcg tcagggagat
     1501 gaaattctgg ttcaggtgga gcgggatgcc gtgaagacaa aggatccggt gctcacctca
     1561 aatctgaatt ttacaggaaa atatctggtt ttaacccagg ggaaaaagca gattggattt
     1621 tctggaaaaa tacgggataa ggcctggaag cagcacatgc agaatctgct ggagaaggag
     1681 acggcaggct catttggact ctcatttgga ctgattgtaa gaactaatgc cagagaagcg
     1741 ggagaggaag agattctgca ggagctggag cttctggcca gacgacgtca gacgcttctg
     1801 gcatctgcct cccaccgcac ctgttacagc cttctggcgt cctctgagcc atcctacatc
     1861 agcagtatcc gcgatgccta cacttctgag ctggaggctg ttgtgactga cgataaggac
     1921 tgctatgagg ctgtccggca gtatctggaa gaaaaccagc cagaggattt ggaaaaactt
     1981 tccttctatg aggatccgat gctgtctctt tccaagctct acagcctgga gactgccctg
     2041 gaacaggctc ttggaaaaca tgtgtggctg aaatccggcg gctatctggt cattgaacca
     2101 acggaggccc tgacggttat tgacgtcaat acaggcaaat atgccgggaa aaagacccag
     2161 gcagaaacca tctttaagat caaccaggag gctgccgcag aaactgcccg gcagctgagg
     2221 ctgcgaaatc tgtccggcat tattgtagta gatttcattg atatggaaac agaagaagag
     2281 aggctgaggc tgatgtctct gctggagcgg gagcttctta aggatccggt caaaacggtg
     2341 ctggtagaca tgacccgtct gggtctggtg gaaattacca gaaaaaaggt aaaacgtcct
     2401 ctggcagagc aggtacgggc agctggatat ccgataaaag aatgctaaaa aattataaaa
     2461 actcaaaact tttctctgta aaccagttga caagtccaga ggaaaatgct attatatcac
     2521 agtatgccgc acagtgaggt ttacaagtcc ggatttccgg cgccgaagct ggcgagtaat
     2581 gataagagga ggtgccatat gtacgcaatt attgcaacag gtggtaagca gtacaaagta
     2641 gccgagggcg atatcattaa agttgagaga cttggtgcag gtgctggtga gacagttacc
     2701 tttgatcagg ttcttgccgt aaacaacggt gagttaaaga tcggatgccc aaccgttgac
     2761 ggtgcaacag tttccgcaac tgtagtaaaa gagggtaaag gcaaaaaggt tatcgtttac
     2821 aagtacaaga gcaaaactgg ctatcacaag aagaacggtc acagacagct cttcacacag
     2881 gttaagattg aaaagatca
//
LOCUS       DBMDUW010000100         2891 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_11874_length_2891_cov_2.584588, whole genome shotgun sequence.
ACCESSION   DBMDUW010000100 DBMDUW010000000
VERSION     DBMDUW010000100.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 2891)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2891)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2891
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_11874_length_2891_cov_2.584588"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            308..838
                     /locus_tag="ACZPCR_11855"
     CDS             308..838
                     /locus_tag="ACZPCR_11855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003502439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006354 - DNA-templated transcription
                     elongation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0140673 - transcription elongation-coupled
                     chromatin remodeling [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination NusG
                     family protein"
                     /protein_id="HIR1231586.1"
                     /translation="MWYVIQTITGKEEELSRAVSAYLSPQICEDCFTVKRRFIRRLGG
                     EWVTVKEILFPSYLFLETAKPEQLFYELKKIPEYTRLLGDNEGSFIPLEAEEKDFLMK
                     ICRREGRDMVADLTDLYLDQNGEIQRAEGPLQFFLDKIVKLNLRKRFAVTELTIAGRK
                     QTAVFGVRLRREELQG"
     gene            879..2081
                     /locus_tag="ACZPCR_11860"
     CDS             879..2081
                     /locus_tag="ACZPCR_11860"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003502442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HIR1231587.1"
                     /translation="MKVPFSPPDITQEEINEAAEALKSGWITTGPRTKEFERQIAAYV
                     GTEKAVCLNSATACMELTLRLLGIGEGDEVITSAYTYTASASVVCHVGAKLKLVDTAP
                     GSYEMDYEQLEQAVTERTKAIIPVDLAGVICDYKRIFEIVEKKRKLFRGNNDIQNALG
                     RIAVIADAAHAFGASRDGKMCGQFADFTSFSFHAVKNLTTAEGGAVVWKEIPGIDSSW
                     IYNQYQLLSLHGQNKDALAKTKLGAWEYDIIGPYYKCNMTDIMAAIGLVQMKRYPGLL
                     KRRRDIIDRYEKGFADLPVETLKHDEGDCHSSRHLYLMRLTGKGVEERNQFIEKLAER
                     GIASNVHYKPLPMHTAYKKLGFDIENYPNAYHMYENEITLPLHTSLTDEQVDYVIHTV
                     RELLLMDR"
     gene            2210..2872
                     /locus_tag="ACZPCR_11865"
     CDS             2210..2872
                     /locus_tag="ACZPCR_11865"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009101 - glycoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HIR1231588.1"
                     /translation="MRTEAVRPYYDSLNRKKGQLFLKRVFDFTVSSLMLAALSPVLAV
                     LAILIRLDSEGPVFYRQERVTQYGRRFRIYKFRTMVQDADKKGSLVTTQGDARITRIG
                     KKLRGCRLDELPQLINIWKGEMSFVGTRPEVVKYVKQYTDEMYATLLLPAGVTSEASV
                     QFKDEDQRIAAGVEAGRIADEVYVEDVLGEKMEINLQELKAFSVAENIKTMIRTVFAM
                     MR"
BASE COUNT          899 a          533 c          796 g          663 t
ORIGIN      
        1 tttataggga gaaaatcaag gatatcaggg ggatttagag aaatttcata gataccggaa
       61 tatcaggaaa atcctaagaa aatctttccc atttctttcc taatgatcct tttcacagat
      121 attgaccgta ttttcaaata gtgttataat cgacaggaat atgatggaga aaatcgtgaa
      181 accttcgtaa agctaatggg gcatatgtaa ggaagaaacg aggttataga tgagagaagc
      241 gttcgggata aaaactattt tttattgcgg atatggcgaa gctataccca aaaacaggag
      301 aacagacatg tggtatgtga ttcagaccat cacagggaag gaagaagagc tgtccagagc
      361 tgtgagcgcc tatctctccc cacagatatg tgaagactgt tttacagtaa aaagaagatt
      421 tatcagacgc ctgggaggag aatgggtgac agtgaaggaa atactctttc cctcctattt
      481 atttttagag acagcaaaac cggagcagct cttttacgag ctgaagaaga taccggagta
      541 tacaaggctg ctgggcgaca acgaaggaag ctttattccg ctggaagcag aggaaaaaga
      601 ctttttaatg aaaatctgcc gcagagaggg cagagatatg gtcgcagacc tgacagacct
      661 gtatttagat cagaacgggg agatccagag agcagaagga cctctccaat tttttttaga
      721 caaaattgta aaattgaacc tgagaaagcg gtttgcagtg acagagctta ccatagcggg
      781 caggaaacag accgctgtgt tcggagtcag gttgaggaga gaggagcttc agggatgagg
      841 ctcttttttg tgtggagaaa acgaaggagg agaagaggat gaaggtacca ttttcaccgc
      901 ctgatattac acaggaggaa atcaatgagg ctgcagaagc cttaaaatct ggatggatta
      961 ccaccggccc cagaaccaag gagtttgagc ggcagattgc ggcctatgta ggaacggaga
     1021 aagcggtctg cttaaattca gctaccgcct gcatggaatt gacgctccgc ctgctgggaa
     1081 ttggagaggg agacgaggtt attacaagcg cctataccta tacggccagc gcaagcgtag
     1141 tctgccatgt gggggcgaaa ctgaagctgg ttgacactgc tccaggttcc tatgagatgg
     1201 attatgaaca gctggaacag gctgtgacag agaggacgaa ggccattatt ccagtggatt
     1261 tggcaggtgt gatctgcgat tacaagagaa tttttgagat agtggaaaaa aagagaaagc
     1321 tgtttcgtgg gaataacgat atccagaacg cgctgggaag gattgctgtt attgctgatg
     1381 ccgcccatgc gttcggagca tccagggatg gaaaaatgtg cggtcagttt gcggatttta
     1441 ccagcttttc tttccacgca gttaaaaacc tcacgacagc agagggcgga gccgtagtct
     1501 ggaaggagat tccaggcatt gacagcagct ggatttacaa tcagtaccag cttctttccc
     1561 tgcacggaca gaataaggat gccctggcta agacaaaact gggagcctgg gaatacgaca
     1621 ttataggccc ctattataag tgcaacatga cagacattat ggctgctatt ggtctggtgc
     1681 agatgaaacg gtatccagga cttttaaagc ggagaagaga tattatcgat cggtatgaga
     1741 agggctttgc ggatcttcca gtggagactc tgaaacacga tgagggggac tgtcattcca
     1801 gccgtcacct gtatttaatg aggctgacag gaaaaggtgt ggaggagagg aatcagttta
     1861 ttgagaagct ggcagagaga ggtatcgcct ccaatgtcca ctacaaacct cttcccatgc
     1921 acacggctta taaaaagctg ggatttgata ttgagaatta tcccaatgct taccatatgt
     1981 atgaaaatga aattaccctg ccgttacata ccagcctgac agatgaacag gtcgattatg
     2041 tcattcatac agtgcgggag cttctgctta tggacagata aaacgatagg aaaaaataca
     2101 tagaaaagga aacagggaga aaatgaccag gcagagcgat aaaaagaaaa agcagaagaa
     2161 tagaaaagag catattcttt ggagagaatg ggaggaactg ccagatttca tgaggacaga
     2221 ggcagtgaga ccctattatg acagcttaaa ccgtaaaaaa ggacagctgt ttctaaaacg
     2281 agtgtttgat tttacggtat catctctgat gctggcggcg ctttctcctg tgctggctgt
     2341 gctggctatt ctgatccgtc tggattcaga ggggccagtt ttttaccgcc aggaacgagt
     2401 cacccagtat ggaagaagat tccgtattta taaattccgc accatggtac aggatgcaga
     2461 taaaaaagga agcctggtga caactcaggg agacgccaga attacgcgga taggaaagaa
     2521 actgagaggc tgccgcctgg atgagcttcc ccagctcatc aatatctgga agggagaaat
     2581 gagctttgtg ggaacccgcc cggaggtagt gaagtatgtg aagcagtata ccgatgaaat
     2641 gtacgctacc ctgcttttac cagcaggcgt cacctcagag gccagcgtcc agtttaagga
     2701 cgaggatcag aggattgcag ccggtgtaga ggcaggcaga atcgcagacg aggtatatgt
     2761 ggaagacgtg ctgggggaga agatggaaat aaacctgcag gaactgaagg cgttttctgt
     2821 agcagagaat ataaagacga tgattcgaac ggtttttgct atgatgaggt aggggtataa
     2881 atatggaaaa a
//
LOCUS       DBMDUW010000101         2867 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_11991_length_2867_cov_2.292480, whole genome shotgun sequence.
ACCESSION   DBMDUW010000101 DBMDUW010000000
VERSION     DBMDUW010000101.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 2867)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2867)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2867
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_11991_length_2867_cov_2.292480"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            48..1352
                     /gene="brnQ"
                     /locus_tag="ACZPCR_11870"
     CDS             48..1352
                     /gene="brnQ"
                     /locus_tag="ACZPCR_11870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016439658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HIR1231589.1"
                     /translation="MLLVSFMLFSLFFGAGNLIFPPFLGQNAGAAAVPALLGFLLTAV
                     VLPVLGVIVVARFNGLDCLANQVGKKFSVVFTILIYLSIGPGLGIPRAASVPFEMAVA
                     PYLPAGSDIKLFMVLYSFVFFLLAFWLCMNPGKLVKRIGSFLTPSLLCLLSILFFSFL
                     FRGKIDVAAPQAAYEMPFFKGFSEGYQTMDTIAALNFGLVIAITLDSFGLKEKKDVMK
                     HTVYAGVFAGSILALVYIMLTYMGMCSSGVYAVQENGAWTLRHIVSQLFGEFGAIILA
                     AIFSLACLTTCVGLINSISQFFSKQFKFFGYRQWVIAITVFSFLVCNLGLNAILSLSI
                     PVLDAIYPVSIVLILMGLSHQVWASNRYVYPMVVTGVSCISVIYALDNAGVPLGFLSD
                     LCHSLPLYDAGFCWVSAALVMLILSFAVNAVMSSRSAACSES"
     gene            1466..>2867
                     /locus_tag="ACZPCR_11875"
     CDS             1466..>2867
                     /locus_tag="ACZPCR_11875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009262007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HIR1231590.1"
                     /translation="MRKLALSDEILLSVQQPARYIGGEVNMVKKDPAGKIRFAMAFPD
                     VYELGMSHLGIQILYDMFNKREDVYCERVYSPWMDLDQIMREKQIPLFALESQDPIKN
                     FDFLGITLQYEMCYTNVLQLLDLAQIPLHACDRTEEDPIVIGGGPCTYNPEPIAEFFD
                     LFYMGEGEVVYFELLDRYKENQAKGGSRREFLELAAEIPGIYVPAFYDVLYKEDGTIE
                     RMVPNNPHAKETVSKQLVMEMNDTYYPEQPVVPFIKATQDRVVLEIMRGCIRGCRFCQ
                     AGMVYRPVRERSLETLKALAYKMLKSTGHEEISLSSLSSSDHTQLEGLVNFLIDEFDG
                     KGVNVSLPSLRIDAFSLDVMSKVQDIKKSSLTFAPEAGSQRLRNVINKGLTEEDILHG
                     SSEAFKGGWNRVKLYFMLGLPTETVEDMEGIALLAEKVAEEYYKVPKEQRFGKVQVVS
                     STSFFVPKPFTPFQWAT"
BASE COUNT          697 a          631 c          701 g          838 t
ORIGIN      
        1 ttatttcttt tgaggaggag aagaaaatga atttgtcacg aagaaaaatg ttattggtaa
       61 gctttatgct gttctctctg ttctttggag caggcaacct gattttcccg ccgtttttag
      121 gccagaatgc aggggcagca gccgttccgg cccttctggg ctttttgctg acagctgtgg
      181 tgcttccggt tcttggcgtt attgttgtcg cacgttttaa cggcctggac tgtctggcca
      241 atcaggtagg aaagaaattt tccgttgtct ttaccatttt aatttatctt tctatcggac
      301 ctggactggg catcccaaga gccgcatccg taccatttga aatggcggta gccccctacc
      361 tgccggcggg atctgatatt aagcttttca tggttctgta ttcttttgta tttttcttgc
      421 tggctttctg gctgtgtatg aatcctggaa agctggtcaa acgaattgga agcttcttaa
      481 ctccaagcct gttatgtctg ctcagcatat tgtttttcag ctttcttttc aggggaaaaa
      541 tcgacgtggc agctcctcag gctgcatatg aaatgccgtt tttcaaaggc ttctcggaag
      601 gataccagac catggatacc atcgcggccc ttaactttgg actggtgatt gccattaccc
      661 ttgattcctt tggcttaaaa gaaaaaaagg atgttatgaa gcataccgtg tatgccggtg
      721 tctttgcagg ttctatcctg gcgcttgttt acatcatgct gacctatatg ggaatgtgca
      781 gttccggtgt gtacgctgtg caggaaaacg gtgcatggac tctgcgtcat attgtatccc
      841 agctttttgg tgaatttgga gctattattc tggcagctat tttctctctt gcctgcctta
      901 ccacctgcgt gggactgatc aattccatct cacagttctt ttcaaaacag tttaaatttt
      961 ttggatacag acagtgggtg attgccatta ccgttttctc gttcctggtc tgcaacctgg
     1021 gactgaatgc aatcttaagt ctttctattc ctgtactcga cgcgatttat cctgtatcta
     1081 tcgtgctgat tcttatgggc ctgtctcatc aggtatgggc gtcaaacaga tatgtctatc
     1141 ctatggttgt tacaggagtc agctgcatca gtgtgattta tgcactcgat aatgccggtg
     1201 ttcctctggg attcctctca gatttatgcc actctctgcc tttatacgat gccggcttct
     1261 gctgggtaag cgcagcgctt gttatgctga tactgagctt tgctgtaaac gcagtcatga
     1321 gcagccgttc agcagcctgc tcagaaagtt agaattaaat ctgcataggg gaaaagaggc
     1381 ttgcttcttt ttgaaatatc acctataatg attcggtatt atccatataa aaatcaattt
     1441 agaaatgcag gtaaaataaa agtttatgag aaaattagcg ttaagtgatg aaatactttt
     1501 aagcgttcag cagcctgccc gttacatcgg cggggaagtg aatatggtga aaaaggatcc
     1561 ggcaggaaag atccgctttg ccatggcttt cccggatgtc tacgagctgg gtatgtccca
     1621 tctgggaatc cagattctct acgatatgtt taacaaaaga gaggacgtct attgtgagcg
     1681 tgtctactcc ccgtggatgg atctggatca gattatgcgg gaaaaacaga ttccgctgtt
     1741 tgccctggag tctcaggatc ccattaagaa ctttgacttt ttgggtatca ctctccagta
     1801 tgaaatgtgc tataccaacg tgcttcagct tctggatctg gctcagattc ctctccacgc
     1861 ctgtgacagg acagaagagg atcctattgt aatcggaggc ggcccctgca cctacaatcc
     1921 agaacctatc gctgaattct tcgacctttt ctacatggga gagggagagg tagtttactt
     1981 tgagctttta gaccgataca aagaaaatca ggcgaaaggc ggcagcagga gagaattctt
     2041 agaactggca gcggaaattc caggcatcta tgtgcctgcc ttttacgatg tcctttataa
     2101 agaagatgga accattgagc ggatggttcc caacaatccc catgcaaaag aaacggtctc
     2161 caagcagctg gtaatggaaa tgaacgatac ctactatccg gaacagcctg tcgttccctt
     2221 catcaaggca acacaggaca gagtcgtgct ggaaattatg agaggctgca tccgcggctg
     2281 ccgtttctgc caggctggca tggtttaccg tcctgttcgt gagagaagtc tggaaacact
     2341 gaaggctctg gcttataaaa tgttaaagag tacaggacat gaagagatct ctttaagctc
     2401 tttaagctcc agcgatcaca cacagctgga gggactggtc aatttcctga ttgacgagtt
     2461 tgacggcaag ggcgtaaacg tctccctgcc ttccctgcgt attgacgcct tctctctgga
     2521 tgtaatgagc aaggtacagg atattaaaaa gagcagtctg acctttgcac cggaggccgg
     2581 ctcccagagg ctgagaaacg taattaacaa gggactgaca gaggaagaca ttctccatgg
     2641 ctcctccgaa gcgtttaaag gcggctggaa ccgggtcaag ctgtatttta tgctgggact
     2701 tcccactgag acagtggagg atatggaagg aatcgctctc ttagctgaaa aagtggcgga
     2761 agagtattac aaggttccca aggagcagcg tttcggtaag gttcaggtag tttccagtac
     2821 ctctttcttt gtgccgaagc catttacgcc tttccagtgg gcaacca
//
LOCUS       DBMDUW010000102         2804 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_12322_length_2804_cov_2.161672, whole genome shotgun sequence.
ACCESSION   DBMDUW010000102 DBMDUW010000000
VERSION     DBMDUW010000102.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 2804)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2804)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2804
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_12322_length_2804_cov_2.161672"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            278..754
                     /locus_tag="ACZPCR_11880"
     CDS             278..754
                     /locus_tag="ACZPCR_11880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005611260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HIR1231591.1"
                     /translation="MMLPRVFGESLFDDLFDDFWDFPSLDDKAMRKAERKLYGHHAAK
                     MMKTDVKEHDDHYEVNIDLPGFKKNEISLELKEGYLVINAAKGLDKDGENKKTGKFVR
                     RERYAGSMSRAFYVGENLKQEDIHAKYENGVLKLNIPKAEEAKKEAEANKYIAIEG"
     gene            1045..2247
                     /locus_tag="ACZPCR_11885"
     CDS             1045..2247
                     /locus_tag="ACZPCR_11885"
                     /inference="COORDINATES: protein motif:HMM:NF012692.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HIR1231592.1"
                     /translation="MDLLSQQTIKAENKKKLYQLISGNSGISRACLASVTSLSKTTVS
                     FLIEELIQEGRIVDQGSIESGRKGRRPNSLSVNSRDCVIVLNWRRHEIWLSLVSAAFE
                     IEAQERESAEPETLGAKALAEKILSFIRRYTEDRSVLGICITVPGMIDSARHQIISMV
                     LALSEEGLIDEIRRLIPEYPISVLNDTACMAYAEQAFGEMEEDSYLYVNINEGIGASL
                     VQNARILHGGTGMGTQLGHFSIDRNGKRCRCGNRGCLENRIGELALPERILENGLNIP
                     LPGKEEGSRILFRDIGQMAGEGNGEAEKLIKILASDLSFALGNFITVLHPDSVVIGGM
                     ARKLGETFLEEIISDLKETGFQFFLDSLDIRFAGLGEEAILTGAARYYIDTHYNFQED
                     LTGKLFLG"
     gene            2262..>2804
                     /locus_tag="ACZPCR_11890"
     CDS             2262..>2804
                     /locus_tag="ACZPCR_11890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007862971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HIR1231593.1"
                     /translation="MERVIAVNSNCYHGYGIFECLEGIHKAGFHYVELTATKGWTEHV
                     FPDQSFEFLTSVKDRMEELFLTPVALSGHCNLMDRERLQDFIMNIRLAGFFGCQYIVS
                     SVGEAHLADRTKTGAQEAAENIRELLPWLEQYDLMLVLETHGEHGTGKAVKEIADLVG
                     SERVRVALVVGAAWGALYRFF"
BASE COUNT          850 a          454 c          777 g          723 t
ORIGIN      
        1 agtgatactg gtaagtattt gtgtttcagc tgtgttgata tggaaattta aaaagaaaaa
       61 atggttataa ttcgctttca aaggaaaggc cataagtgat cacaaaaaat tcacaaaaaa
      121 aacagcgatc agtcttgaca actgttaata tgcgtgttat aacacggata gaacagaggg
      181 aaggagaaat aaggagaaat gaatagacaa agatttcgct tttctcctag acttctggtt
      241 aacaatttag ctttaacaca aaaaggagcg atgacttatg atgttgccta gagtttttgg
      301 tgaaagttta tttgatgatt tgtttgatga cttttgggat tttccgtcgc tggatgataa
      361 agcgatgcgt aaagcagagc gcaagctgta tggacatcat gcagcaaaaa tgatgaagac
      421 ggatgtgaag gaacatgatg accattatga ggtaaacatt gacctgcctg gtttcaagaa
      481 aaatgagatt tccctggagc tgaaagaggg ctatctggtg attaacgctg caaaggggct
      541 tgacaaagac ggagagaata aaaaaacagg taaatttgtc cgccgggagc gttatgcagg
      601 cagcatgagc agagctttct atgtgggaga gaatttaaag caggaagata ttcatgcgaa
      661 atatgaaaat ggtgtattga agttaaacat tccaaaggct gaggaggcaa agaaggaggc
      721 agaggcaaac aagtatattg ccatcgaggg ataaatagaa agaggataat aaaggctctg
      781 gagctgtttt tctgtaatgg gaaacagaat atccagggcc ttttttattt tatgtaaaat
      841 tttttattct tccagcttcg aatacaggaa aactggctat tttgacaaaa cctgtatgga
      901 tataaatgaa aatatataga aaactgctaa aaaataactt gcgccggaaa taaaaaagtg
      961 ttagtattta gttagtccac tggactaact aattaaacat atgtgttcac tggagataga
     1021 actaacagag aaaacaaggg ggggatggat ttgctcagtc agcagacaat caaggcggag
     1081 aataagaaaa agctgtatca gctgatctca gggaattccg ggatatccag agcctgtctt
     1141 gcctccgtga cgtctctcag caagacgacc gtatcttttt taatagagga actgatccag
     1201 gaaggcagaa ttgtcgatca gggcagcatt gaaagcggaa gaaaagggag acgccctaac
     1261 agcctgtctg tgaacagccg cgactgtgtg attgtattga actggagacg ccatgaaata
     1321 tggctttctc ttgtgtcagc tgcctttgaa atagaagctc aggagcgtga gagcgcagag
     1381 ccggagacac tgggagcgaa agccctggcg gagaagattt tatcttttat tagacgctat
     1441 acagaagaca gaagtgttct tggcatctgc attacagtac ctggaatgat tgacagcgcc
     1501 agacaccaga ttatttctat ggtattagcg ctttcagagg aaggactgat tgacgaaatc
     1561 aggaggctga ttccggagta tcctatttct gttctcaatg atacggcctg tatggcctat
     1621 gcagagcagg ccttcggaga gatggaagag gacagctatt tatatgtaaa tattaatgaa
     1681 ggaattggtg caagcctggt gcagaatgcc aggattcttc atggcggtac tggcatgggg
     1741 acccagctgg ggcatttttc cattgacaga aatggaaaga gatgccgctg tggaaacaga
     1801 ggatgcctgg aaaacaggat tggtgagctg gctctgccag agaggattct ggaaaacggt
     1861 cttaatattc ctcttccggg aaaagaggag ggaagcagga ttttattccg ggatatcggg
     1921 cagatggctg gtgaaggaaa tggggaggct gaaaagctga taaaaattct ggcatcagat
     1981 ttgagttttg cccttggaaa ttttattact gtgcttcatc ctgattctgt ggtgatcgga
     2041 ggaatggcca gaaagctggg agaaacattt ttagaggaga ttatttctga tttaaaagaa
     2101 acgggatttc agtttttcct ggatagtctg gatatccggt ttgcaggact gggtgaggaa
     2161 gcgattttga caggagcagc caggtattac attgatacgc attacaactt tcaggaggat
     2221 ctgacaggca aactgttttt agggtagaag gaggagaaga tatggaacgt gtgattgccg
     2281 ttaattcaaa ctgttaccat gggtatggga tttttgaatg tctggaggga atacacaagg
     2341 ctggttttca ctatgtggaa ctgacagcca ccaagggctg gactgagcat gtatttccgg
     2401 atcagagttt tgagtttctt acatcagtaa aggacaggat ggaggagctg tttttaacgc
     2461 ctgttgcact cagcggccac tgtaatctga tggaccggga gcgtcttcag gattttatca
     2521 tgaatatccg cctggcagga tttttcggct gccagtacat tgtgtcgtcc gtgggggagg
     2581 cgcacctggc agatcggaca aagaccgggg cacaggaagc agctgagaat atcagggagc
     2641 ttctgccgtg gctggagcag tatgatctga tgctggttct ggaaactcat ggagagcatg
     2701 gaacaggaaa agcagtaaaa gagattgcgg acctggtagg ctcagagaga gtcagagtgg
     2761 ctttggtggt gggggcggca tggggggcgc tttaccgttt cttt
//
LOCUS       DBMDUW010000103         2612 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_13445_length_2612_cov_2.928315, whole genome shotgun sequence.
ACCESSION   DBMDUW010000103 DBMDUW010000000
VERSION     DBMDUW010000103.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 2612)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2612)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2612
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_13445_length_2612_cov_2.928315"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..602)
                     /gene="nadD"
                     /locus_tag="ACZPCR_11895"
     CDS             complement(<1..602)
                     /gene="nadD"
                     /locus_tag="ACZPCR_11895"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD+ biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HIR1231594.1"
                     /translation="MKKIGIMGGTFDPIHSGHLMLGKQAYEEYDLDCVWYMPSRQPPH
                     KKDRHITSPADRLEMVRLAVESTPFFACSDFELCRTEGNTYTADTLLLLKQAYPDTEF
                     YFIVGADSIFDIEKWYHPEIVMKNAVILAADRACGHDDVPFSRQIEYLTKKYDARICR
                     LHSRRMDVSSQLLRQKIQNGEQVSGYIPDPVVQFIRERRL"
     gene            complement(634..927)
                     /gene="yhbY"
                     /locus_tag="ACZPCR_11900"
     CDS             complement(634..927)
                     /gene="yhbY"
                     /locus_tag="ACZPCR_11900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005332792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HIR1231595.1"
                     /translation="MTSKQRAYLKGLAMKIDPIFQIGKSSVTPELTAAVAEALEAREL
                     IKLSVLKNCLDDGNSIAAVLAERTHSQVVQVIGKKIVLYKPAKDEKKRKIVLP"
     gene            complement(941..2233)
                     /gene="obgE"
                     /locus_tag="ACZPCR_11905"
     CDS             complement(941..2233)
                     /gene="obgE"
                     /locus_tag="ACZPCR_11905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007864523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HIR1231596.1"
                     /translation="MFADSAKVFIRSGKGGDGHVSFRRELYVAAGGPDGGDGGKGGDV
                     IFEVEDGLNTLTDFRHVRKYAAQDGESGGKRRCHGADGDNIIIKVPEGTVIKDFESGK
                     VIADMSGSNRREVILKGGKGGLGNMHFATSTMQVPKYAQPGQPAQELWVQLELKVIAD
                     VGLVGFPNVGKSTLLSRVSNARPKIANYHFTTLNPHLGVVDLSEGQGFVMADIPGLIE
                     GASQGVGLGYAFLKHIERTKVLVHVVDAASTEGRDPVADIRAINEELRAYNPELLTRP
                     QVIAANKTDAIYFDPENGEENPVDRLKAEFEPEGIQVFAISAVSGQGVKELLYHINEL
                     LKTVDQTPVIFEKEFEYQYQGENLPYTVEQNEEGVFVVEGPKIEKMLGYTNLDSEKGF
                     QFFQRFLKDSGILEELERAGIEEGDTVRMYGLKFDYYK"
     gene            complement(2319..2609)
                     /gene="rpmA"
                     /locus_tag="ACZPCR_11910"
     CDS             complement(2319..2609)
                     /gene="rpmA"
                     /locus_tag="ACZPCR_11910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002567613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HIR1231597.1"
                     /translation="MFKMNLQLFAHKKGVGSTKNGRDSESKRLGAKRADGQFVLAGNI
                     LYRQRGTKIHPGINVGRGGDDTLFAMVDGVVRFERKGRDKKQVSVYPRAINE"
BASE COUNT          616 a          691 c          565 g          740 t
ORIGIN      
        1 tagagccgac gctctctgat aaactgcacc acaggatccg ggatatagcc ggagacctgc
       61 tctccgtttt gtattttctg tctcagaagc tgagacgata cgtccatccg cctggagtgc
      121 agccggcaga ttctggcgtc gtactttttt gtcagatatt caatctgacg gctgaaagga
      181 acatcgtcat ggccgcaggc gcggtcagcc gccagaataa cagcgttttt catcacaatt
      241 tcgggatgat accatttttc tatatcgaaa atagaatcag ctcctactat aaaataaaat
      301 tctgtgtcag gataagcctg ctttaacagg agcagcgtat cggcagtata ggtattcccc
      361 tccgttctgc acagctcaaa gtcagaacag gcaaaaaagg gcgtgctttc aacagccagg
      421 cgaaccatct ccaggcggtc agccggagat gtaatgtggc gatccttttt gtggggaggc
      481 tgcctggacg gcatatacca gacacagtcc agatcatact cctcataggc ctgttttccc
      541 agcatcagat ggccggagtg aatgggatca aaggttcctc ccataatacc gatttttttc
      601 atttctgcca gctcctttca gatattctga tgcctatggc agcacaattt ttctcttctt
      661 ttcatcctta gcaggcttgt agagaacgat tttctttccg attacctgga ctacctggga
      721 atgggttctc tcggctaata cggccgcaat ggaattgccg tcgtccagac agtttttcag
      781 aacgctcagc ttgatgagct ctctcgcctc cagggcctct gctactgcag cggtaagctc
      841 cggagttacg cttgactttc caatctggaa aatcggatct attttcatag caagcccttt
      901 taaataggct ctctgtttac ttgtcataat ttatcccctg ttatttgtaa tagtcaaatt
      961 tcaggccata catgcggacg gtatcgccct cttcaattcc ggccctttca agttcctcta
     1021 aaattccgga atccttcagg aagcgctgga agaactggaa gcccttctca gaatccaggt
     1081 tggtatagcc cagcattttt tcgatcttcg gtccctcaac cacaaagact ccctcttcgt
     1141 tctgttcaac cgtatatgga agattttctc cctgatactg gtattcaaat tctttctcaa
     1201 aaatgacagg agtctgatcg acggttttta aaagctcgtt gatatggtaa aggagctcct
     1261 ttacaccctg tccgctgact gcggaaatcg cgaatacctg aattccctcc ggctcaaatt
     1321 ctgccttcag gcgatccaca ggattttcct ctccgttttc cggatcaaag taaatcgcgt
     1381 ctgttttatt ggccgcgata acctgaggac gtgtcagcag ctcaggattg taagctctaa
     1441 gctcctcgtt gatagccctg atatcggcta ccggatcgcg tccttctgtg gatgcggcgt
     1501 ctaccacatg aaccagaact ttggttcttt caatgtgttt taagaaagcg tagccaaggc
     1561 ctacgccctg ggaagctccc tcgataagcc ctggaatatc ggccataaca aagccctgtc
     1621 cttcgcttaa atcgacaact ccgagatgtg gattcagagt tgtgaaatgg taattggcga
     1681 ttttaggtct cgcatttgat acacgggaaa gcagagtaga tttaccaaca tttggaaagc
     1741 ctacaaggcc tacatcagcg attaccttta attccagctg tacccaaagc tcctgagccg
     1801 gctgtcccgg ctgcgcgtac ttaggaacct gcatggtgga tgtggcaaag tgcatattac
     1861 ccagaccgcc ttttccgccc tttaagatta cctcacgtcg gttggagccg gacatatcgg
     1921 caatgacctt tcccgattca aagtctttga taactgttcc ttcaggaacc ttgataataa
     1981 tattgtcacc gtctgctccg tggcagcggc gctttccgcc ggattcgccg tcctgggccg
     2041 catatttgcg gacatggcga aagtctgtca gagtgttcag tccatcttct acttcaaaaa
     2101 taacgtctcc gccttttccg ccgtccccac cgtccggacc gccggcagct acgtagagtt
     2161 cacgtctgaa gctgacatgg ccgtctccgc cttttccgga tctgataaat acttttgcgc
     2221 tgtcggcaaa catagcaaca cctgtccctt tctctgtgat ctatcgtctg tctgtaacca
     2281 aaaacagccc catacgataa ggtatggagc tgcttgaatt attcgttaat tgctcttggg
     2341 taaacagaaa cctgcttttt gtctctgccc tttctctcaa atctaacaac gccgtcaacc
     2401 atagcgaata atgtatcatc tccaccgcgg cctacgttga tacctggatg aatctttgta
     2461 ccacgctgtc tgtaaagaat gttgccagct aatacaaact gtccgtctgc tctcttagct
     2521 cccagtctct tggactcgga atcacggccg ttctttgtgg aaccaacacc ttttttgtga
     2581 gcgaataact gaaggttcat tttaaacatc ac
//
LOCUS       DBMDUW010000104         2612 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_13447_length_2612_cov_1.870171, whole genome shotgun sequence.
ACCESSION   DBMDUW010000104 DBMDUW010000000
VERSION     DBMDUW010000104.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 2612)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2612)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2612
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_13447_length_2612_cov_1.870171"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..187)
                     /locus_tag="ACZPCR_11915"
     CDS             complement(<1..187)
                     /locus_tag="ACZPCR_11915"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007592792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1231598.1"
                     /translation="MCRNKEKKVSIIMPAYNAEKYIEEAIYSVLAQTHKEWELIIIDD
                     CSSDNTEQIVLKYVSKDT"
     gene            complement(174..1574)
                     /locus_tag="ACZPCR_11920"
     CDS             complement(174..1574)
                     /locus_tag="ACZPCR_11920"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HIR1231599.1"
                     /translation="MKNYEQYKRLMRGAFCLILLAVQAGMFWCVWKKEYSPLMESPYW
                     RKGHWLLLAVYIFLIFIFPKIYGGWKVGYLRVFNLLYSQFLGTLLANGTMYLIITLLT
                     KHFENPTMMAIMTLCQTAVMIVWGFFANRIYQKTYPPRKVLMVYGERPAAGLMQKLHT
                     REDRFEIGEMVHISEGVQKIEALIEDKTKGYGGVVICDIPSRERNQILKYCYGKGVRT
                     YTTPKISDVIVRSAESLHMFDTPLLMSRNTGLTVEQRAVKRAVDIIISLIAFIPAAPI
                     MALVALCIKLDDGGSVLYKQKRLTEGGKEFFVYKFRSMREDAEKDGVARLAGENDDRI
                     TRAGHIIRAIRFDELPQLINILRGDMSIVGPRPERPEIAEDYEKEIPEFAYRLKAKAG
                     LTGYAQVYGKYNTTAYDKLKLDLMYIQNYSLRLDFEIMFKTVQILFMKESTEGVEDGQ
                     VTAIGKQNRKESYVQK"
     gene            complement(1974..2504)
                     /locus_tag="ACZPCR_11925"
     CDS             complement(1974..2504)
                     /locus_tag="ACZPCR_11925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006354 - DNA-templated transcription
                     elongation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0140673 - transcription elongation-coupled
                     chromatin remodeling [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination NusG
                     family protein"
                     /protein_id="HIR1231600.1"
                     /translation="MSWYVLQCRVGQEREIIASLRQRLSSEALSAAFLFQSERLWRAG
                     GGVWKLITKDMFPGYVFMESENPEKLSRELEEYRGIVRILEEPGYLYSVYAEEEKRLL
                     ALCGPEHVLRLSYGYRENGVNCLIDGPLKGIESQIIKADWHRRFAQVEIPVSGKKTIV
                     WAGLGLPEERNLWRAG"
BASE COUNT          622 a          701 c          464 g          825 t
ORIGIN      
        1 ttgtatcttt gctgacatat tttaaaacaa tttgctctgt attatcagat gaacagtcgt
       61 caattataat aagctcccat tctttgtgcg tttgagctaa aacagaataa atggcttctt
      121 ctatgtattt ttctgcatta tacgctggca taataatgct gactttcttt tccttatttc
      181 tgcacataac tttctttcct gttttgcttc cctatcgccg tcacctgtcc gtcctccacg
      241 ccttccgtgc tctccttcat aaacaggatc tgcaccgttt tgaacatgat ctcgaagtcc
      301 aggcgcaggc tgtaattctg gatatacatc agatccagct tcagtttgtc gtaggccgtc
      361 gtgttgtatt taccgtacac ctgcgcgtag ccggtaagac ctgcttttgc cttcagacgg
      421 taggcaaact ctggtatttc cttttcgtaa tcttcagcga tctcaggccg ctctggtctg
      481 ggccctacaa tgctcatatc tccccgcaga atattaatca gctgaggaag ctcgtcaaag
      541 cggatagctc ggataatgtg ccctgcccgc gtaatgcgat cgtcattttc ccccgccagt
      601 ctggctacgc cgtccttctc tgcatcctct ctcatacttc gaaatttata aacaaaaaat
      661 tcttttccgc cttctgtcag acgtttctgc ttatagagca cacttccgcc atcatccagt
      721 ttaatgcaca gggctacaag cgccataatc ggagcagctg gaataaaggc aatcagagaa
      781 ataataatat ccaccgcccg tttgactgcc cgctgttcta cggtcagtcc cgtatttcgt
      841 gacatcaaaa gcggcgtgtc aaacatgtga aggctttccg cacttcttac aatgacgtca
      901 gaaattttcg gcgtggtata ggttctgact cctttgccgt aacagtattt taaaatctga
      961 tttcgttccc tgctgggaat atcgcagata acaactcctc catagccctt ggttttatcc
     1021 tctatcagag cttctatttt ctgaactcct tcagaaatat gtaccatttc tcctatttca
     1081 aagcgatcct ctctggtatg aagcttctgc ataaggcctg ctgccggacg ttctccatat
     1141 accatcagca ccttcctggg cggataagtc ttctggtaaa ttctgtttgc gaaaaatccc
     1201 cagacaatca taaccgccgt ctgacagaga gtcataatcg ccatcatagt cggattctca
     1261 aaatgcttcg tcagcagcgt aataataaga tacatggttc cgtttgccag aagcgttcct
     1321 aaaaactgcg aatacagaag attaaatacc ctcaggtatc ctaccttcca tccgccgtat
     1381 attttaggaa aaataaaaat aaggaaaata taaactgcca aaagcagcca gtgtcccttt
     1441 ctccaataag gactttccat caaagggctg tattcctttt tccacacaca ccaaaacata
     1501 ccagcctgaa cggccaggag aatcaggcag aacgctcctc tcatcagccg tttgtactgt
     1561 tcataattct tcatttgtat cttccatcct gatttttgca atatttctgt tatttctaat
     1621 tatgattaat ctttcaatct tctgcccgat cccctatttc ctggcatggc ccgggccgta
     1681 cagctgataa tagcagtctt tgcagagctg tcctgctcct tctatataaa agctgcgctc
     1741 tgaaatatcc atttctcttg gaatatctgt ctgttttccg caagaaacac aaatttcaaa
     1801 agctcctgat ccactggttt cttctatttc tctgttttct ttttcctgtt ctaatcgatt
     1861 cctgtccatg tgcttttcgg actgttttct ccagccgctt ctccttttca tactgatttt
     1921 cgttttacca tcttcccgcc gcaatatgtg gtttacgatt cctgactgct tctctatcct
     1981 gctctccaca ggttcctttc ttccggcaga cctaaaccgg cccaaacaat ggttttcttt
     2041 ccggatacag gaatttctac ctgggcaaat ctgcggtgcc agtctgcctt tatgatctgg
     2101 ctctctattc cctttaacgg gccgtctatc aggcagttca cgccgttttc cctgtatccg
     2161 taagaaaggc gaaggacatg ttccggcccg cacagtgcga gaaggcgttt ctcctcttct
     2221 gcatagacag aatataaata tcctggctcc tctaaaatcc ttacgattcc tcggtattct
     2281 tccagttctc ttgataattt ctccggattt tcactctcca taaagacata gcccggaaac
     2341 atatcctttg taatcagctt ccagactccc cctccagccc gccagaggcg ttcgctctga
     2401 aataaaaaag ctgctgataa tgcttcgctg gataggcgct gcctcaaaga ggcaattatt
     2461 tcccgttcct gtccaactct gcactgcagg acgtaccagc tcataagcca gccctcctcc
     2521 ttttatacat tttcctgtcg cttaatagat agttaagcga cactttttgc cagaggccct
     2581 tatccgttat ttcgttataa aaaatggaat ct
//
LOCUS       DBMDUW010000105         2597 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Otoolea sp. isolate MAG1246
            NODE_13543_length_2597_cov_2.887821, whole genome shotgun sequence.
ACCESSION   DBMDUW010000105 DBMDUW010000000
VERSION     DBMDUW010000105.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508345
            Sequence Read Archive: ERR10114003
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Otoolea sp. (human gut metagenome)
  ORGANISM  Otoolea sp.
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae; Otoolea.
REFERENCE   1  (bases 1 to 2597)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2597)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 3.6366x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:58:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,387
            CDSs (total)                      :: 2,332
            Genes (coding)                    :: 2,297
            CDSs (with protein)               :: 2,297
            Genes (RNA)                       :: 55
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 35
            CDSs (without protein)            :: 35
            Pseudo Genes (ambiguous residues) :: 0 of 35
            Pseudo Genes (frameshifted)       :: 7 of 35
            Pseudo Genes (incomplete)         :: 26 of 35
            Pseudo Genes (internal stop)      :: 6 of 35
            Pseudo Genes (multiple problems)  :: 3 of 35
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2597
                     /organism="Otoolea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_13543_length_2597_cov_2.887821"
                     /isolate="MAG1246"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:3032831"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(194..1135)
                     /locus_tag="ACZPCR_11930"
     CDS             complement(194..1135)
                     /locus_tag="ACZPCR_11930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1231601.1"
                     /translation="MCYPCNETSYSCGFPCPPSCIPSPVLPEHCSSPVAIGQTITGQP
                     GTAAAVHNSGTPCRPVLNFTIPQGGTGPEGPAGPQGPVGPEGPQGAAGADGAQGIQGP
                     MGPQGSQGPAGPTGPMGLTGPIGATGPTGPMGLTGPAGATGPAGPTGPMGLTGPAGAT
                     GPAGPTGPMGPAGSAPAAELLHSVHVPAQEPEDAGLPLIFNTNQVQAGTSITHTAGTG
                     VFSIVRSGIYQILYSVTATDAAAHKTVTVELRNTGVSIPGSRTSGSTPMSTGTASLSA
                     SIILNVTGTASISLVPVTADSTFTNASIQLIRLGNAV"
     gene            complement(1303..2331)
                     /locus_tag="ACZPCR_11935"
     CDS             complement(1303..2331)
                     /locus_tag="ACZPCR_11935"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003498941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HIR1231602.1"
                     /translation="MGFEYVSKLPTPDEIRAQFPLAPALAAEKAKKDEAIKDVFTGKS
                     DKFLVIIGPCSADREDSVCEYVSRLTKVQEKVKDKLILIPRIYTNKPRTTGDGYKGLL
                     HQPNPEQKPNLYEGLIAIRKLHMRVIEETGFSTADEMLYPENLTYLSDVMSYIAVGAR
                     SVENQQHRLVSSGIDVPVGMKNPTSGALSVMLNAVHAAQHGHEFIYRSWEVKTEGNPL
                     THCILRGAVNKHDQCLPNYHYEDLKLLHELYAERNLKNPACIVDANHSNSNKQYMEQI
                     RIVKEVLHSRRHSSDIRDFVKGVMIESYLEPGSQKVGEHCYGKSITDPCLGWDDSERL
                     LYEIAEGI"
BASE COUNT          624 a          611 c          725 g          637 t
ORIGIN      
        1 agtatacaaa cattttcggg agaaccgtgc tatactaaaa ccataataaa tgcacgatac
       61 aaaagtaata aaaacctttt aagctttttg aaattccgaa aatcctaacg aaagagtccc
      121 tgcaccgaaa ggtgcaggga ttttttcgtt cacagaaaag tgatgatttc tgctgaaacg
      181 caagttcgta tgatcagact gcatttccca gcctgataag ctggatggat gcgttggtaa
      241 aggtactgtc ggcagtgaca ggtaccaggg aaatggacgc cgtgccggtt acgttcagaa
      301 taatggacgc agacagggag gcagtgcctg tactcatagg cgtgcttccg gaagtgcggc
      361 tgcctggaat ggaaacgccg gtgtttcgaa gctccacagt cacagtcttg tgggcggccg
      421 catctgtggc tgtgaccgag tagaggatct ggtagatacc agatctgaca atggagaaga
      481 cgccagtacc tgcggtgtgg gtgatggagg ttccggcctg aacctggttt gtattaaaaa
      541 tcagaggcag tccggcgtcc tctggttcct gtgcaggaac atggacggag tgaagaagct
      601 ctgcggctgg agcagaaccg gcaggcccca tcggcccagt cggccccgca ggtccggtcg
      661 ctccagcagg tccggttaat cccatcggcc cggtcggtcc agcaggtccg gttgctccgg
      721 caggtccggt taatcccatt ggcccagttg gcccggtcgc tccgataggt ccggttaatc
      781 ccatcggccc agtcggcccg gcaggcccct ggcttccctg aggccccatc ggtccctgaa
      841 ttccctgtgc gccgtcagct ccggctgcgc cctgaggtcc ttctggccct acaggcccct
      901 gaggtccggc agggccttcc ggtccggtac cgccctgtgg aatcgtaaaa tttagaaccg
      961 ggcggcaggg ggtgccgctg ttgtgcacgg cggcggctgt tccaggctgc cccgtgatgg
     1021 tctggcctat ggcgacaggg gaagagcagt gttccggtaa aaccggggaa ggaatacagg
     1081 aaggcggaca tgggaagccg caggaataag aagtttcatt gcatggataa cacataagat
     1141 ttgtcctttt caggttgttt tactatacta tatgcaggga tgtacttttt gacagtccgg
     1201 tgaaataagg gagaaaaaga gctttcataa aacaaaaacc gcctttccgt cactggacgg
     1261 aaaagcggcc ttttgtagat attgaatgtt tgattcagat agttagattc cctcggcgat
     1321 ctcatagaga aggcgttcag aatcatccca tcccaggcag ggatctgtga tggattttcc
     1381 atagcagtgt tcgcccacct tctgggatcc cggctctaag tagctctcaa tcatcacgcc
     1441 cttcacaaag tcgcggatgt cagaggagtg gcggcgggaa tggagcacct ccttaacaat
     1501 acgaatctgc tccatatact gcttgttgga gttggagtgg ttcgcgtcca caatgcaggc
     1561 aggattcttc agatttctct ctgcatagag ctcgtggagc agcttcagat cctcgtaatg
     1621 gtagttgggc aggcactggt catgtttatt gacagcgccg cgcagaatgc agtgagtcag
     1681 aggatttccc tctgtcttta cctcccagct tctgtagata aactcgtggc cgtgctgggc
     1741 agcgtgaact gcgttgagca taacggagag agcgccgctg gtggggtttt tcatgcccac
     1801 gggcacgtca atgccgctgg atacaaggcg gtgctgctga ttctctacag agcgggcgcc
     1861 tacggcgatg taggacataa cgtcggaaag atacgttaag ttttccggat aaagcatctc
     1921 gtcagctgtg gagaagccgg tttcctcgat tacccgcatg tgaagctttc tgatggcaat
     1981 gaggccctca tagagattgg gcttctgctc cgggttgggc tgatggagca ggcccttgta
     2041 gccgtctcca gtagttctcg gcttattggt gtagattctg ggaatcagaa tcagcttgtc
     2101 ctttactttt tcctgcacct tggtcagacg ggacacgtac tcgcagacag agtcctcccg
     2161 atcagcggag caggggccga tgataacgag aaatttatcg ctttttcctg taaacacgtc
     2221 cttaatagcc tcgtcttttt ttgctttttc tgctgccaga gccggggcca gcggaaactg
     2281 cgccctgatc tcatctggag ttggaagctt gctgacatat tcaaatccca tggtataatc
     2341 ctcctgaaaa tagataaata ttcatgttta aatacgaatg tgtgtgtggc tacattataa
     2401 tatagaaatc acgcttcggc aaggtctgag agtgggaaaa tgcagaattt atgcataaat
     2461 ataaaaacaa tatgttttct atgcatggcg ccggaggata aattgacgga tatgacacaa
     2521 aattgtaaaa tttagttaac aaaatagggc aggaagcttg acggaagaga agattcatat
     2581 tagaatagga tggaata
//
